Question: What are The Ready Set and Cell?

<P0-S0> The retinoblastoma protein (protein name abbreviated pRb; gene name abbreviated RB or RB1) is a tumor suppressor protein that is dysfunctional in several major cancers. <P0-S1>  One function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide. <P0-S2>  When the cell is ready to divide, pRb is phosphorylated, becomes inactive and allows cell cycle progression. <P0-S3>  It is also a recruiter of several chromatin remodeling enzymes such as methylases and acetylases. <SEP> <P1-S0> Within the field of developmental biology one goal is to understand how a particular cell (or embryo) develops into the final cell type (or organism), essentially how a cell's fate is determined. <P1-S1>  Within an embryo, 4 processes play out at the cellular and tissue level to essentially create the final organism. <P1-S2>  These processes are cell proliferation, cell specialization, cell interaction and cell movement. <P1-S3>  Each cell in the embryo receives and gives cues to its neighboring cells and retains a cell memory of its own cell proliferation history. <P1-S4>  Almost all animals undergo a similar sequence of events during embryogenesis and have, at least at this developmental stage, the three germ layers and undergo gastrulation. <P1-S5>  While embryogenesis has been studied for more than a century, it was only recently (the past 15 years or so) that scientists discovered that a basic set of the same proteins and mRNAs are involved in all of embryogenesis. <P1-S6>  This is one of the reasons that model systems such as the fly ("Drosophila melanogaster"), the mouse (Muridae), and the leech ("Helobdella"), can all be used to study embryogenesis and developmental biology relevant to other animals, including humans. <P1-S7>  What continues to be discovered and investigated is how the basic set of proteins (and mRNAs) are expressed differentially between cells types, temporally and spatially; and whether this is responsible for the vast diversity of organisms produced. <P1-S8>  This leads to one of the key questions of developmental biology of how is cell fate determined. <SEP> <P2-S0>  He is the lead vocalist and sole member of the act, using a backup band while on tour. <P2-S1> Jordan Mark Witzigreuter (born November 14, 1989), known professionally as The Ready Set, is an American singer-songwriter from Fort Wayne, Indiana. <P2-S2>  Witzigreuter created The Ready Set in the basement of his childhood home in Fort Wayne, Indiana. <P2-S3>  He has released four studio albums "Tantrum Castle", "I'm Alive, I'm Dreaming," "The Bad & The Better", and "I Will Be Nothing Without Your Love," four extended plays and seven singles. <P2-S4>  Fall Out Boy bassist Pete Wentz signed The Ready Set to his label Decaydance Records, in 2009. <P2-S5>  He is currently with Hopeless Records. <SEP> <P3-S0>  The band formed in 1990 and split c.1995. <P3-S1> Cell were a New York-based band often tagged with the label of Grunge given the time frame of their existence, though college rock or alternative is arguably a more apt description. <P3-S2>  Championed by Sonic Youth's Thurston Moore, they released a 7 inch on his Ecstatic Peace label, and later signing to Geffen.