Original: Pelosi is Italian-American and was born Nancy Patricia D'Alesandro in Baltimore, Maryland, the youngest of six children of Anunciata M. ("Nancy") and Thomas D'Alesandro, Jr., who was a Democratic party U.S. Congressman from Maryland and a Mayor of Baltimore. Pelosi's brother, Thomas D'Alesandro III, also a Democrat, was mayor of Baltimore from 1967 to 1971, when he declined to run for a second term.
Simplified: Her brother, Thomas D'Alesandro III, also was Mayor of Baltimore.