Original: After Carl's best man and friend Randolph Dupree (Owen Wilson), loses his job and apartment, the couple allow him to move in but Dupree inevitably overstays his welcome.
Simplified: After Carl's best man and friend Randolph Dupree (usually just called "Dupree") (Owen Wilson), loses his job and apartment, the couple allow him to move in but Dupree inevitably overstays his welcome.