Original: Sickle-cell disease (SCD), or sickle-cell anemia (or anemia; SCA) or drepanocytosis, is an autosomal recessive genetic blood disorder, with overdominance, characterized by red blood cells that assume an abnormal, rigid, sickle shape.
Simplified: This is a life long disease and a life long blood disorder, sickle cell disease or sickle-cell anemia, characterized by red blood cells that have an abnormal, rigid, sickle shape.