Input (grade 11): It was discovered that beri beri could be prevented by regularly eating thiamine-rich soba.
Output (grade 12): At that time, the population of Edo (Tokyo) was considerably wealthier than the rural poor, were more susceptible to beri beri because of their high consumption of white rice which is low in thiamine. They are thought to have made up for this by regularly eating thiamine-rich soba.