Input (grade 13): After purging three planets of Phazon (including the Space Pirate homeworld), the Federation locates the source of Phazon, planet Phaaze, which is made entirely of Phazon.
Output (grade 12): Samus is infected by one of these and is almost killed, but someone gives her a shot of Metroid DNA that kills the X virus, but also makes her immune to being killed by them.