Alfonsina Orsini ( 1472 -- 7 February 1520 ) was the spouse of Piero di Lorenzo de ' Medici from 1488 and the mother of Lorenzo II de ' Medici .
Alfonsina Orsini ( 1472 -- 7 February 1520 ) was a Regent of Florence . 
 She was the spouse of Piero di Lorenzo de ' Medici from 1488 and the mother of Lorenzo II de ' Medici .