It is unknown whether THC - C4 is agonistic or antagonistic to cannabinoid receptors , the propyl anolog , THCV is known to be antagonistic , while THC is an agonist .
It is unknown whether THC - C4 is an agonist , partial agonist , or antagonist at the cannabinoid receptors . 
 The propyl anolog , THCV is a known antagonist while THC itself is an agonist .