Recent DNA evidence suggests that several haplotypes of Neanderthal origin are present among all non-African populations, and Neanderthals and other hominids, such as Denisova hominin may have contributed up to 6% of their genome to present-day humans.<ref name="10.1126/science.1209202"> Anatomically modern humans evolved from archaic Homo sapiens in the Middle Paleolithic , about 200,000 years ago.