Nutritionists are advising people to eat more fish, since the omega-3 fatty acids in fish help combat many diseases. If everyone took this advice, however, there would not be enough fish in oceans, rivers, and lakes to supply the demand; the oceans are already being overfished. The obvious method to ease the pressure on wild fish populations is for people to increase their consumption of farmed fish. Which of the following, if true, raises the most serious doubt concerning the prospects for success of the solution proposed above? ['The feed for farmed ocean fish is largely made from small wild-caught fish, including the young of many popular food species.', 'There are large expanses of ocean waters that do not contain enough nutrients to support substantial fish populations.', 'Some of the species that are now farmed extensively were not commonly eaten when they were only available in the wild.', 'Some fish farming, particularly of shrimp and other shellfish, takes place in enclosures in the Ocean.']