['There are many immunological changes in preeclampsia. For example, TLR-4 expression is increased in the placenta during preeclampsia. However, data on TLR expression in other tissues during preeclampsia are lacking. This study aimed to determine whether TLR mRNA expression in maternal neutrophils is altered in preeclampsia.', 'A case-control study using standard quantitative real-time PCR techniques was performed to assess TLR-2 and TLR-4 mRNA expression in 12 patients with mild preeclampsia and 18 normal pregnant controls at similar gestational ages.', 'Compared to normal pregnant controls, there was a significant decrease in TLR-2 and TLR-4 expression in women with mild preeclampsia.'] Is maternal neutrophil toll-like receptor mRNA expression down-regulated in preeclampsia?