['Structural imaging studies demonstrate brain tissue abnormalities in eating disorders, yet a quantitative analysis has not been done.', 'In global and regional meta-analyses of 9 voxel-based morphometry (VBM) studies, with a total of 228 eating disorder participants (currently ill with anorexia nervosa), and 240 age-matched healthy controls, we compare brain volumes using global and regional analyses.', 'Anorexia nervosa (AN) patients have global reductions in gray (effect size\u2009=\u2009-0.66) and white matter (effect size\u2009=\u2009-0.74) and increased cerebrospinal fluid (effect size\u2009=\u20090.98) and have regional decreases in left hypothalamus, left inferior parietal lobe, right lentiform nucleus and right caudate, and no significant increases. No significant difference in hemispheric lateralization was found.'] Is anorexia nervosa linked to reduced brain structure in reward and somatosensory regions : a meta-analysis of VBM studies?