['Coagulation disorders are frequently diagnosed, especially in hospitalized equidae, and result in increased morbidity and mortality. However, hemostatic reference intervals have not been established for donkeys yet.', 'To determine whether the most common coagulation parameters used in equine practice are different between healthy donkeys and horses.', 'Thirty-eight healthy donkeys and 29 healthy horses.', 'Blood samples were collected to assess both coagulation and fibrinolytic systems by determination of platelet count, fibrinogen concentration, clotting times (prothrombin time [PT] and activated partial thromboplastin time [aPTT]), fibrin degradation products (FDP) and D-Dimer concentrations.', 'PT and aPTT in donkeys were significantly (P < .05) shorter than those of horses. In contrast, FDP and D-Dimer concentrations were significantly (P < .05) higher in donkeys than in horses.'] Are coagulation profiles of healthy Andalusian donkeys different than those of healthy horses?