['It is known that use of hormone replacement therapy (HRT) by postmenopausal women increases the risk of breast cancer.', 'In this study, oestrogen receptor (ER)-alpha expression is examined using standard immunoperoxidase technique.', 'Normal breast samples of 11 Australian postmenopausal women have been included in the ER-alpha study; the result showed a strong correlation (r(2) = 0.80) between ER-alpha expression in normal breast epithelial cells and body mass index (BMI) in normal women who currently use HRT.'] Does hormone replacement therapy use dramatically increase breast oestrogen receptor expression in obese postmenopausal women?