['To study the value of the cervical length (CL) measurement at 11-14 weeks in predicting second trimester miscarriage occurring at 16-24 weeks.', 'Prospective study in routine obstetric population using transvaginal ultrasound examination to measure the length of the endocervical canal at 11-14 weeks.', 'The study group consisted of 2836 singleton pregnancies. Eleven (0.0038%) women miscarried between 16 and 24 weeks whereas 2825 delivered after 34 weeks. CL was significantly shorter (Mann-Whitney U test, p\u2009=\u20090.001), in women that had a second trimester miscarriage in comparison to those who delivered after 34 weeks (median CL 28\u2009mm versus 32\u2009mm, respectively). First trimester CL was predictive of a late miscarriage (OR\u2009=\u20090.7093304, R(2\u2009)=\u20090.1211, AUC\u2009=\u20090.7838, p\u2009<\u20090.001). The detection rate was 63.64% for 20% screen positive rate.'] Is first trimester cervical length associated with mid-trimester loss?