Hoping to rebound from their humiliating home loss to the Patriots, the Bills flew to Jacksonville Municipal Stadium for a Week 12 duel with the Jacksonville Jaguars.  For QB J. P. Losman, he was playing to keep his starting job. In the first quarter, Buffalo trailed early as Jaguars RB Fred Taylor got a 50-yard TD run, along with kicker Josh Scobee getting a 46-yard field goal.  In the second quarter, Jacksonville increased its lead with Scobee kicking a 33-yard field goal.  The Bills managed to get on the board with Losman's 10-yard TD pass to RB Anthony Thomas.  The Jaguars would end the half with Scobee getting a 22-yard field goal. In the third quarter, Jacksonville increased its lead with Scobee kicking a 23-yard field goal. Buffalo managed to respond with WR Roscoe Parrish getting a 24-yard TD run on a reverse.  However, in the fourth quarter, the Jaguars took control for the rest of the game as Scobee nailed a 20-yard field goal, QB David Garrard completing a 59-yard TD pass to WR Reggie Williams, and RB Maurice Jones-Drew getting a 17-yard TD run.. How many yards was the longest touchdown run?