['The purpose of the study was to determine whether exercise-induced increases in energy expenditure (EE) alter circulating leptin levels in obese individuals.', 'Participants were randomized to an exercise intervention group (n = 8) or nonexercising control (n = 7).', 'All data were collected on an outpatient basis at the exercise physiology laboratory at the University of Central Florida.', 'Fifteen healthy obese males (24.9 +/- 1.4 years old, body mass index 33.4 +/- 0.7 kg . m).', 'Members of the intervention group underwent a single exercise session of moderate intensity (58.4 +/- 1.3% of VO2max) for 60 minutes.', 'Postexercise, 24 hour postexercise, and 48 hour postexercise levels of leptin, insulin, and ghrelin.', 'The exercise session elicited an EE of 567 +/- 25 Kcal. No significant main effect or time-by-group interactions for leptin or ghrelin were observed immediately after the exercise bout or in the days following the intervention.'] Does moderate exercise-induced energy expenditure alter leptin levels in sedentary obese men?