As an edible sugar, fructose has been widely used in the food processing industry. Fructose stays in the blood after entering human cells, and its metabolic pathway in the human body is not related to insulin, and human intake does not cause blood sugar and insulin levels. Therefore, fructose has a smaller effect on glucose in patients with diabetes than glucose, and diabetes patients do not increase their blood glucose significantly after ingesting fructose. Therefore, fructose is a sugar that is good for health. If the following are true, which of the following can't weaken the above conclusion? ['In people with high fructose intake, the incidence of obesity and obesity-related diseases is significantly higher and average.', 'Fructose enters the body and is more easily converted into triglycerides than glucose, eventually producing more fat and accumulating in the internal organs.', 'Fructose is hydrolyzed from starch. Starch first breaks down into glucose and then transforms the mixture of fructose and glucose, so fructose does not come from fruits.', 'Long-term intake of large amounts of fructose can lead to increased insulin resistance, which is thought to reduce the sensitivity of insulin to changes in blood glucose, and in severe cases can lead to diabetes.']