The Colts suffered their first defeat of the season, 21-14, at the hand of the Dallas Cowboys and became the last team to lose during the 2006 NFL season. The game was full of turnovers, and neither team could take care of the scoring opportunities. Colts QB Peyton Manning threw two interceptions and one of those was returned for a touchdown by Cowboys OLB Kevin Burnett early in the second half. The first quarter was back-and-forth as each possession ended with turnover after turnover. After Cowboys QB Tony Romo was sacked by DE Dwight Freeney, Colts WR Marvin Harrison fumbled, and after the Cowboys punted, Manning was sacked by Jay Ratliff and Bradie James recovered the fumble. After a couple punts by both teams, Peyton Manning & Co. pushed the Cowboys deep in their own territory thanks to the great rushing by rookie RB Joseph Addai. The Colts reached the 4-yard line, and on third down, Manning attempted a pass to the endzone, but in a controversial situation, SS Roy Williams nudged TE Dallas Clark near the end zone, and while Clark fell down, Williams intercepted a Peyton Manning pass for the second time in his career, and gave the Cowboys the ball at their own 7-yard line. The Cowboys scored all of their points in the second half after a first half that was full of turnovers. Colts QB Peyton Manning went 20 of 39 for 254 passing yards with two touchdown passes and two interceptions, Cowboys QB Tony Romo was 19 of 23 with 226 passing yards and had one interception. Colts WR Reggie Wayne had 7 catches for 111 yards, and Cowboys RB Julius Jones rushed the football 22 times for 79 yards. Also of note, former Colts kicker Mike Vanderjagt missed two of his three field goals during the game.. How many games have the Colts lost?