['To study a potential association between male infertility and DMRT1 mutations.', 'Retrospective sequencing study.', 'University hospital.', '171 patients with cryptozoospermia (sperm concentration<0.1 million/mL, n=40) or nonobstructive azoospermia (n=131), and 215 normozoospermic controls.', 'Sequence analysis of DMRT1.', 'Identification of rare variants in DMRT1 that are associated with male infertility.', 'In total, we detected four putative pathogenic mutations in six patients (3.5%) and less frequently in two controls (0.9%).'] Are dMRT1 mutations rarely associated with male infertility?