['Recent studies have highlighted the influence of alpha1-adrenoceptor antagonists on ejaculatory function.', 'We evaluated the effect of a new, highly selective alpha1A-blocker, silodosin, on ejaculatory function of normal volunteers.', 'The study included 15 healthy male urologists who voluntarily participated in the study. They took 4 mg of silodosin or a placebo twice daily for 3 days in a randomized, double-blind crossover design.', 'We investigated the ejaculatory volume, sperm count in urine after ejaculation, and fructose concentration in seminal plasma before and after administration of the agents.', 'All volunteers on silodosin had a complete lack of ejaculation. Three days after completion of silodosin, the mean ejaculatory volume recovered to the baseline level. There was no sperm in urine after ejaculation under silodosin administration in any volunteer.'] Is inhibition of Seminal emission the main cause of anejaculation induced by a new highly selective alpha1A-blocker in normal volunteers?