['There are many possible predisposing factors for Achilles tendon disorders suggested in the literature but their pathogenetic relevance is not proven in most cases. The asymmetric mechanical load distribution within the Achilles tendon during locomotion is frequently addressed as a major risk factor for Achilles tendon disorders. The spatial orientation of the subtalar joint axis (STA) may influence the Achilles tendon loading possibly leading to overload injuries. Hypothesis There is a significant difference between the orientation of the STA in subjects with and without Achilles tendon pathologies.', '614 subtalar joint axes determined in 307 long-distance runners with and without Achilles tendon disorders were included. Achilles tendon disorders were defined as any Achilles tendon-related pain during or following running, existing for more than 2 weeks in the past. Motion analysis of the foot was performed using an ultrasonic pulse-echo-based measurement system. The orientation of the STA was expressed by two angles.', 'The mean inclination angle was 42 ± 16° and the mean deviation angle was 11 ± 2 3°. There was a significant difference (p=0.002) between the mean deviation angle measured in subjects with Achilles tendon pathologies (18 ± 23°) and those without (10 ± 23°).'] Is spatial orientation of the subtalar joint axis different in subjects with and without Achilles tendon disorders?