['To assess the association between the body fat distribution and axial bone mineral density (BMD) in postmenopausal women with or without hormone replacement therapy (HRT).', 'Cross-sectional population-based study.', 'University of Eastern Finland, Bone and Cartilage Research Unit, Kuopio, Finland.', '198 postmenopausal women, mean age 67.5 (1.9 SD), mean BMI 27.1 (3.9 SD).', 'Regional body composition and BMD assessed by dual X-ray absorptiometry (DXA, Prodigy).', 'Spinal and Femoral BMD.', 'Out of the body composition parameters, FM was the main determinant of postmenopausal bone mass. Only the lumbar spine (L2-L4) BMD, not the femoral neck BMD, was positively associated with the trunk FM. Positive trends for association were revealed between the spinal BMD and the trunk FM regardless of the use of HRT. Adjustments did not change the results.'] Is body fat distribution associated with lumbar spine bone density independently of body weight in postmenopausal women?