A research institution surveyed and analyzed 208 patients with symptoms such as heartache and arrhythmia, and reported their views on the condition through questionnaires when they started surgery. About 20% of them were very worried that the condition would worsen, and some people Even fear of death, others will not have so much worry. Later follow-up surveys showed that those who were seriously worried about preoperatively had a higher recurrence rate than other people in the first half of the year. Researchers believe that worrying is not conducive to the rehabilitation of heart disease. Which of the following, if true, would best support the above conclusion? ['Some studies show that worrying emotions can inhibit prefrontal cortex activity of the brain and make people more depressed.', 'Researchers find that those with serious concerns are more concerned about their health.', 'Those with serious concerns have chemicals in their blood that increase the risk of heart disease.', 'Worry is a potential threat to health, and people cause many diseases such as cancer, diabetes.']