['To assess the disinfection efficacy of multipurpose solutions (MPS) against different bacterial species adhered either to silicon hydrogel or to conventional hydrogel contact lenses (CLs). The influences of the MPS formulation and the chemical composition of the lens material were investigated.', "This investigation followed the standard 14729, which establishes the guidelines for assessing CL disinfecting solutions. Two commercially available (Opti-Free(®) Express(®) and Renu(®) Multiplus) solutions and one recalled solution (Complete(®) MoisturePlus™) were used in this study. After disinfection, the number of survivors was estimated by the colony forming units' method.", 'The lens material appears to influence disinfection. The conventional hydrogel polymacon exhibited the highest disinfection scores, a fact that should be related with the lack of electrostatic attraction towards the biocides and its hydrophilicity. The MPS formulation appears to have influence in disinfection efficacy as well. For most adhered bacteria, Opti-Free(®) was capable of reducing cell concentration in 4-log.'] Does lens material and formulation of multipurpose solutions affect contact lens disinfection?