['Hepatitis C virus (HCV) infection is widespread, abhorrently under-diagnosed, and radically under-treated. Globally, infection with HCV is a major cause of acute hepatitis and chronic liver disease. Therefore, novel HCV inhibitors are required for the treatment of the HCV infected patients.', 'This review gives the detailed knowledge of upcoming therapy such as NS5B polymerase inhibitors that are urgently needed.'] Do a review on an update of NS5B polymerase hepatitis C virus inhibitors?