['Two siblings from consanguineous parents of Turkish descent presented with isolated dilated cardiomyopathy, leading to early death in infancy. The diagnosis of mitogenic cardiomyopathy was made histologically.', 'Linkage analysis combined with exome sequencing identified a homozygous deleterious mutation in the ALMS1 gene as the cause of this phenotype.'] Does homozygous loss-of-function mutation in ALMS1 cause the lethal disorder mitogenic cardiomyopathy in two siblings?