Observations in laboratory experiments and clinical trials show that some commonly used antibacterial drugs should be taken on an empty stomach, because food can affect the absorption of the drug or significantly reduce the drug utilization rate after taking it after a meal. Which of the following options best support the above assertions:. ['Antibacterial drugs, not very irritating to the stomach and intestines, can be taken on an empty stomach.', 'Antibacterials suitable for fasting are only a small part of all antibacterials.', 'People want to increase the efficacy of drugs when they take them.', 'In the past, the use of antibacterial drugs was obviously unreasonable.']