['Four cardiac hormones, namely, vessel dilator, long-acting natriuretic peptide, atrial natriuretic peptide and kaliuretic peptide, have anticancer effects but whether they cause cell death of human cancer cells or normal cells is unknown.', 'These cardiac hormones were examined for their ability to cause cell death quantified by measurement of nuclear matrix proteins 41/7 which is a function of the number of dead or dying cells.', 'Each of these cardiac hormones caused cell death in up to 36% (p < 0.0001) of the pancreatic adenocarcinoma cells and up to 28% (p<0.0001) of the prostate cancer cells over a concentration range of 100 pmol/l to 10 μmol/l. There was no cell death of normal human prostate, kidney, or lung cells at the above concentrations.'] Do four cardiac hormones cause death of human cancer cells but not of healthy cells?