['Small animal model has not been available to study cardiac pathophysiology during hemorrhagic shock. The main purpose of this study, therefore, was to establish earlier differences in left ventricle functional disturbances during hypovolemia comparable in survival and nonsurvival animals. Ventricular pressure-volume relationships have become well established as the most rigorous and comprehensive venue to assess intact heart function.', 'Studies were performed in anesthetized hamsters subjected to a 40% of blood volume hemorrhage to induce the hypovolemic shock. A miniaturized conductance catheter was used to measure left ventricular pressure and volume. Derived from the pressure-volume measurements, cardiac performance was evaluated using systolic and diastolic function indices.', 'Thirteen animals were included; all animals survived the hemorrhage. Survival rate after 30 minutes of hypovolemic shock was 61.5%. End-systolic pressure was improved at the late stage of shock in the survival group, whereas no change of this index was found in the nonsurvival group. No significant differences in end-diastolic pressure and relaxation time constant were found between the nonsurvival and the survival groups. Fifteen minutes after the hemorrhage, the stroke work per stroke volume ratio significantly improved in the survival compared with nonsurvival, which also restored blood pressure.'] Does cardiac systolic function recovery after hemorrhage determine survivability during shock?