['After viewing dynamic noise surrounding a homogeneous grey patch (artificial scotoma), observers perceive a prolonged twinkling-noise after-image within the unstimulated area. It has been suggested that noise-stimulated neurons induce a long-range inhibition in neurons within the artificial scotoma, which generates a rebound signal perceived as twinkling noise following noise termination. We used this paradigm to test whether migraineurs have enhanced excitability or weakened inhibition.', 'Twinkling-noise duration was measured in 13 headache-free volunteers, 13 migraineurs with aura and 13 migraineurs without aura.', 'The durations of the after-image were significantly shorter for both migraine groups compared to controls.'] Are long-range inhibitory mechanisms in the visual system impaired in migraine sufferers?