['We aimed to further validate the vasoactive-ventilation-renal score as a predictor of outcome in patients recovering from surgery for congenital heart disease. We also sought to determine the optimal time point within the early recovery period at which the vasoactive-ventilation-renal score should be measured.', 'We prospectively reviewed consecutive patients recovering from cardiac surgery within our intensive care unit between January 2015 and June 2015. The vasoactive-ventilation-renal score was calculated at 6, 12, 24, and\xa048\xa0hours postoperatively as follows: vasoactive-ventilation-renal score = ventilation index + vasoactive-inotrope score\xa0+\xa0Δ creatinine [change in serum creatinine from baseline*10]. Primary outcome of interest was prolonged hospital length of stay, defined as length of stay in the upper 25%. Receiver operating characteristic curves were generated, and areas under the curve with 95% confidence intervals were calculated for all time points. Multivariable logistic regression modeling also was performed.', 'We reviewed 164 patients with a median age of 9.25\xa0months (interquartile range, 2.6-58\xa0months). Median length of stay was 8\xa0days (interquartile range, 5-17.5\xa0days). The area under the curve value for the vasoactive-ventilation-renal score as a predictor of prolonged length of stay (>17.5\xa0days) was greatest at 12\xa0hours postoperatively (area under the curve\xa0=\xa00.93; 95% confidence interval, 0.89-0.97). On multivariable regression analysis, after adjustment for potential confounders, the 12-hour vasoactive-ventilation-renal score remained a strong predictor of prolonged hospital length of stay (odds ratio, 1.15; 95% confidence interval, 1.10-1.20).'] Does vasoactive-ventilation-renal score reliably predict hospital length of stay after surgery for congenital heart disease?