['To determine if peroneal bypass is a suitable alternative to inframalleolar bypass in patients with ischemic pedal gangrene.', 'Review of a prospectively acquired vascular registry.', 'University practice limited to vascular surgery.', 'Patients with chronic lower-extremity ischemia and pedal gangrene evaluated between 1985 and 1995 in whom the only options for arterial reconstruction were bypass to the peroneal or an inframalleolar artery.', 'Peroneal or inframalleolar reverse vein bypass.', 'Time to healing and lifetable analyses of survival, primary patency, and limb salvage.', 'Eighty-three peroneal and 46 pedal bypasses were performed for ischemic foot gangrene. The groups were equivalent for sex, diabetes mellitus, heart disease, hypertension, renal failure, hypercoagulable states, previous ipsilateral bypass, smoking, and preoperative ankle-brachial indices. Patients with inframalleolar bypass were younger than patients with peroneal bypass (63.9 vs 71.6 years, P = .005) and had higher postoperative ankle-brachial indices (1.02 vs 0.91, P = .004). However, 3-year survival rates (69.1% inframalleolar vs 60.0% peroneal, P = .35), limb salvage rates at 2 years (70.3% vs 85.8%, P = .10), and time to wound healing (19.7 vs 21.6 weeks, P = .66) were equivalent.'] Is peroneal bypass equivalent to inframalleolar bypass for ischemic pedal gangrene?