['To specify indications to plasmapheresis (PA) and to assess its efficiency in patients with hypercoagulatory syndrome in hematogenic thrombophilia (HT).', '18 patients (11 males, 7 females, age 26-50 years) with various forms of HT received standard antiaggregation, anticoagulatory therapy plus therapeutic PA. By PA technique the patients were divided into two groups.', 'A positive trend in clinical, instrumental and laboratory indices was observed in all the patients.'] Do [ Plasmapheresis in combine therapy of hypercoagulation syndrome in hematogenic thrombophilia ]?