['To investigate whether apoptin is a apoptosis-inducing protein with a potential for bladder cancer therapy.', 'We constructed a PCDNA3/Apoptin eukaryotic expression vector, and transfected this vector into bladder cancer cell lines BIU-87 and EJ, then observed the results by RT-PCR, transmission electron microscopy, MTT assay and the flow cytometry (TUNEL method).', 'PCDNA3/Apoptin successfully induced a high level apoptosis in both bladder cancer cell lines, compared with the controls (p<0.05).'] Does apoptin induce apoptosis in human bladder cancer EJ and BIU-87 cells?