Following their close win against the Jets, the Colts returned home for a Week 5 matchup with AFC South rival Tennessee. Surprisingly, the Titans took the lead early as rookie QB Vince Young ran 19 yards for a touchdown in what would be the first quarter's only score. In the second quarter, Tennessee expanded its lead to 10-0 on a 22-yard Rob Bironas field goal. Indianapolis cut the deficit with six minutes left in the third quarter on QB Peyton Manning's 13-yard touchdown strike to WR Marvin Harrison. However, Tennessee countered on Rob Bironas' 47-yard field goal, which gave the Titans a 13-7 lead going into the fourth quarter. Showing the resolve that allowed them to come from behind in their two previous games, the Indianapolis offense delivered what turned out to be the game-clinching score with only five minutes left in the fourth quarter on a 2-yard touchdown pass from Peyton Manning to WR Reggie Wayne to give the Colts a 14-13 lead. That ended up being the final score after Vince Young could not convert on a hail mary pass in the end zone. With the win, the Colts stayed undefeated and expanded their lead in the AFC South to two games over second place Jacksonville. Peyton Manning finished the game 20 of 31 for 166 passing yards with 2 touchdown passes and one interception, and Vince Young finished with 63 passing yards on 10 of 21 pass attempts and threw one interception also. Tennessee running back Travis Henry had 123 rushing yards in the loss.. How many points did the Titans lead with in the fourth quarter?