['To describe two infants with cholestatic jaundice treated with ursodeoxycholic acid (UDCA).', 'Two infants with cystic fibrosis (CF)-associated hepatobiliary disease, manifesting as cholestatic jaundice and elevated liver enzymes within the first 6 weeks of life, had improved biochemical indices of liver function following treatment with UDCA 20-40 mg/kg/d.'] Does ursodeoxycholic acid improve cholestasis in infants with cystic fibrosis?