The Genoese occupation of Rhodes refers to the period between 1248 and late 1249/early 1250 during which the city of Rhodes and parts of the island were under Genoese control. The Genoese took possession of the city and island, a dependency of the Empire of Nicaea, in a surprise attack in 1248, and held it, with aid from the Principality of Achaea, against Nicaean attacks until 1250.. How many years did the Genoese occupation of Rhodes last?