['Calprotectin is a fecal marker of intra-intestinal inflammation derived from activated enteric neutrophils and macrophages. It is useful as a clinical marker in inflammatory bowel diseases; furthermore, it may have a role in public health epidemiology.', 'To describe the distribution of fecal calprotectin in Guatemalan preschool children sharing a common institutional diet; to relate it collectively to pediatric distributions in other geographic settings, and individually to concomitant indicators of intestinal infection or colonization and other descriptive features of the child.', 'Fecal samples were collected in 87 subjects, aged 2-7 years across 3 daycare centers sharing a common institutional menu, but from different ecological settings. Stools were examined, variously by routine light microscopy, quantitative egg counts, and a Giardia antigen test, for microbiological diagnosis, as well as an ELISA assay for fecal calprotectin (CalproLab).', "The median fecal calprotectin value was 58\u200amg/kg, with a mean of 98\u200a±\u200a136\u200amg/kg and a range from 10 to 950\u200amg/kg; 61% of values were above the manufacturer's cut-off for elevated concentration and 51% exceeded an age-adjusted criterion. There were no associations for sex, age, growth indicators, or fecal microbiological findings by microscopy or ELISA assays, alone or in combination. The central tendency (mean or median) and distribution were generally shifted to the right in relation to comparable reports from children across the world literature."] Are normative Fecal Calprotectin Concentrations in Guatemalan Preschoolers High Relative to Children Reported Elsewhere?