Doctors caution people that smoking and drinking are harmful to health, but some scholars have found from statistics that some people who never smoke and drink according to customs have a life expectancy that is 5-10 years shorter than those who often smoke and drink. Therefore, scholars speculate that smoking Although drinking may damage lung and liver functions, it does not necessarily affect life expectancy. Which of the following, if true, would best challenge the above view? ['Smoking and drinking can make the brain euphoric, relieve stress and feel happy.', 'The nations that have banned tobacco and alcohol according to customs have relatively simple diets and high calories.', 'Smoking and drinking are important causes of lung cancer and liver cancer, which are in the top two of the disease death spectrum.', 'Tobacco and alcohol can stimulate the brain to secrete dopamine, let the organs of the body enter a relaxed state, and promote body repair.']