['According to current guidelines, skin testing for hymenoptera venom allergy should be performed in a stepwise manner, maintaining 15- to 20-min intervals between the injections of venom. Given the long-winded procedure of sequential skin testing, we retrospectively explored the safety of simultaneous intradermal testing.', 'Four hundred and seventy-eight consecutive patients with a convincing history of an anaphylactic reaction after a hymenoptera sting were tested. All venom concentrations (0.02\xa0ml of 0.001, 0.01, 0.1, and 1.0\xa0μg/ml of honey bee and wasp venom) were administered simultaneously to the skin.', 'Four hundred and seventy-two (98.7%) patients tolerated the simultaneous intradermal test without any side-effects. Only three subjects (0.6%) had a presumed allergic reaction during the test; another three reactions were considered vasovagal.'] Is simultaneous intradermal testing with hymenoptera venoms safe and more efficient than sequential testing?