['To determine the association between sleep quality and lower urinary tract symptom (LUTS) severity in men working non-standard shifts, a population at risk for poor sleep quality.', 'Men who presented to a single andrology clinic between July and October 2014 and worked non-standard shifts completed the International Prostate Symptom Score (IPSS) and responded to questions regarding their work habits, sleep-quality, and physical/cognitive function. We assessed the relationship between age, sleep-quality, physical/cognitive function and severity of LUTS.', '228 men with a mean±SD age of 41.8±5.7 (range 21-76) years reported working non-standard shifts with the majority working these for more than 1 year (81%). Men with difficulties falling asleep reported more severe LUTS than men who did not have difficulty falling asleep (IPSS score 9 vs. 6, p<0.001). Men who reported difficulty staying asleep or falling back asleep after awakening also reported more severe LUTS (IPSS scores 6 vs. 13, p=0.004; 5 vs. 13, p<0.001, respectively). Men with a decreased sense of wellbeing or decreased physical/cognitive function also reported more severe LUTS (IPSS score 6 vs. 9, p<0.0010; 6 vs. 10, p=0.016, respectively). All findings were independent of subject age.'] Is impaired Sleep Quality Associated with More Significant Lower Urinary Tract Symptoms in Male Shift Workers?