['To identify a screening strategy for dry eye patients with a high likelihood of having Sjogren syndrome (SS) through the evaluation of the association of ocular surface tests with the extraocular signs used for the diagnosis of SS.', 'Multicenter cross-sectional study.', "The Sjogren's International Clinical Collaborative Alliance (SICCA) registry enrolled 3514 participants with SS or possible SS from 9 international academic sites. Ocular surface evaluation included Schirmer I testing, tear breakup time (TBUT), and staining of the cornea (0-6 points) and conjunctiva (0-6 points). Multivariate logistic regression analysis was performed to identify predictive factors for (1) histopathologic changes on labial salivary gland (LSG) biopsies (positive\xa0= focus score of ≥1 focus/4\xa0mm", 'The adjusted odds of having a positive LSG biopsy were significantly higher among those with an abnormal Schirmer I test (adjusted OR\xa0= 1.26, 95% CI 1.05-1.51, P\xa0= .014) and positive conjunctival staining\xa0(for each additional unit of staining 1.46; 95% CI 1.39-1.53, P < .001) or corneal staining (for each additional unit of staining 1.14; 95% CI 1.08-1.21, P\xa0< .001). The odds of having a positive serology were significantly higher among those with an abnormal Schirmer I test (adjusted OR\xa0= 1.3; 95% CI 1.09-1.54, P\xa0= .004) and conjunctival staining (adjusted OR\xa0=\xa01.51; 95% CI 1.43-1.58, P < .001).'] Does association of Dry Eye test With Extraocular Signs Among 3514 Participants in the Sjögren 's Syndrome International Registry?