['Macrophage M2b polarization conferred by self-DNA immunization initiates and propagates lupus nephritis.', 'Knockdown of DNA-dependent activator of interferon-regulatory factors (DAI) ameliorates SLE syndrome via blunting macrophage M2b polarization.'] Does dNA-dependent activator of interferon-regulatory factors ( DAI ) promote lupus nephritis by activating the calcium pathway?