['to evaluate the performance of Anyplex II HPV28 and HPV HR Detection assays against the EuroArray HPV, Cobas 4800 HPV (Cobas), HPV Amplicor (Amp), Linear Array HPV (LA) and Hybrid Capture 2 (HC2) in detection of high-risk HPV (HR-HPV) from liquid-based cervical cytology samples.', 'cervical specimens from 404 women undergoing management of high-grade cytological abnormality were evaluated by Anyplex II HPV28 and HPV HR Detection assays for detection of HR-HPV genotypes and prediction of histologically-confirmed cervical intraepithelial neoplasia grade 2 or higher (≥CIN2). The results were compared to EuroArray, HC2, Cobas, Amp, and LA.', 'specimens were evaluated from 404 women with an average age of 30\xa0years, including 336 with a histological diagnosis of\u2009≥\u2009CIN2 and 68 with\u2009≤\u2009CIN1. Concordance of HR-HPV detection between Anyplex II HPV28 and other genotyping assays was 94.79\xa0% (κ\u2009=\u20090.84; EuroArray) and 97.27\xa0% (κ\u2009=\u20090.91; LA); and between Anyplex II HPV HR and other HR-HPV detection assays was 86.35\xa0% (κ\u2009=\u20090.62; HC2), 96.03\xa0% (κ\u2009=\u20090.87; Cobas) and 96.77\xa0% (κ\u2009=\u20090.89; Amp). Using HR-HPV detection for prediction of\u2009≥\u2009CIN2 by Anyplex II HPV28 and HPV HR, sensitivity (90.18, 95\xa0% CI 86.48-93.14; 90.77, 95\xa0% CI 87.16-93.65) and specificity (both 67.16, 95\xa0% CI 54.60-78.15) were not significantly different to the other HPV assays tested, with one exception. Both Anyplex assays had significantly higher sensitivity than HC2 (p\u2009<\u20090.0001), with a specificity of 96\xa0% (p\u2009>\u20090.05) of HC2 in this high-risk population.'] Are anyplex II HPV28 detection and Anyplex II HPV HR detection assays highly concordant with other commercial assays for detection of high-risk HPV genotypes in women with high grade cervical abnormalities?