['Although a fragility fracture family history (FFFH+) has repeatedly been shown to be associated with lower bone mineral density (BMD), its relationship to human BMD ', 'Healthy premenopausal community women participated in prospective observational studies at two academic medical research centres: Vancouver, Canada (n\u2009=\u200966) and Munich, Germany (n\u2009=\u200920). The primary outcome was annual spinal BMD change, measured by quantitative computed tomography (QCT). The two studies employed similar methodologies for assessing QCT and FFFH.', 'Volunteer community participants had a mean age of 36.0 (SD, 6.9) years, body mass index 22.5 (2.4) and baseline QCT of 150.2 (22.5) mg/cm'] Is premenopausal Trabecular Bone Loss Associated with a Family History of Fragility Fracture?