Still on the hunt for their first win of the season the Bills played on home ground for an interconference duel with the Lions. In the 2nd quarter the Bills took the lead after RB Fred Jackson got a 1-yard TD run. In that quarter the Lions only came away with a 25-yard field goal by Dave Rayner. The Bills increased their lead in the third quarter with QB Ryan Fitzpatrick completing a 16-yard TD pass to Jackson. The Lions tried to come back in the 4th quarter with Rayner making a 45-yard field goal and with QB Shaun Hill throwing a 20-yard TD pass to WR Calvin Johnson. The two-point conversion attempt failed, giving the Bills their first victory of the season and eliminating their chances of a winless season.. In which quarters did only one team score?