['To demonstrate the effects of DHEAS/free testosterone (DHEAS/FT) ratio on metabolic parameters in women with and without polycystic ovary syndrome (PCOS).', 'The data of 91 women with PCOS and 66 women in the control group were collected retrospectively.', 'DHEAS/FT of the control group was higher than that of PCOS group (684.93\u2009±\u2009300.54 to 517.2\u2009±\u2009300.8, p\u2009<\u20090.001). DHEAS/FT correlated with BMI (r\u2009=\u2009-0.352, p\u2009=\u20090.001), WHR (r\u2009=\u2009-0.371, p\u2009=\u20090.0219), LDL (r\u2009=\u2009-0.227, p\u2009=\u20090.031), HOMA-IR (r\u2009=\u2009-0.36, p\u2009=\u20090.001) and FAI (r\u2009=\u2009-0.639, p\u2009=\u20090.001) negatively and with HDL (r\u2009=\u20090.344, p\u2009=\u20090.001) and SHBG (r\u2009=\u20090.646, p\u2009=\u20090.001) positively. In the control group, DHEAS/FT correlated with BMI (r\u2009=\u2009-0.334, p\u2009=\u20090.007), CRP (r\u2009=\u2009-0.297, p\u2009=\u20090.016) and FAI (r\u2009=\u2009-0.399, p\u2009=\u20090.01) negatively.'] Is high DHEAS/free testosterone ratio related to better metabolic parameters in women with PCOS?