Solving the problem of combining science and technology with the economy has always been the core of the reform of the science and technology system. Previous reforms have adopted a series of measures from the commercialization of technology, the operation mechanism of science and technology, the organizational structure, and the personnel system, mainly focusing on the micro-organizational level. To this day, we need to think more from the macro-management level. In other words, the reform has been changed to the government managers who promote the reform of the science and technology system. Does the concept of government science and technology resource allocation need to change? Do we need to change the mode of scientific and technological activity management? Does the organization that manages science and technology activities need to be adjusted? After answering these three questions, it is possible to solve the "two skins" problem of technology and economy. What does this text mean? ['Thinking about the reform of the science and technology system from the perspective of government management.', 'Immediate reform of the national science and technology system is imminent.', 'Clarifying government responsibilities is an important prerequisite for the reform of the scientific and technological system.', "The disjunction of technology and economy is a drawback of China's science and technology system."]