['Secondary analysis of Lumbar Epidural steroid injections for Spinal Stenosis randomized controlled trial data.', 'To re-evaluate whether outcomes for older adults receiving epidural steroid injections with or without corticosteroid improve after using patient-prioritized Roland-Morris Disability Questionnaire (RDQ) items.', 'Epidural corticosteroid injections are commonly used to treat lumbar spinal stenosis symptoms, despite limited evidence for their effectiveness in clinical trials. It is unclear whether evaluating patient-prioritized outcomes would alter results of a large clinical trial.', 'Outcomes from the LESS trial were re-analyzed using RDQ, Sickness Impact Profile- SIP weights assigned to the RDQ items, and patient-prioritized RDQ items. Differences between corticosteroid+lidocaine versus lidocaine-alone groups and 95% confidence intervals (CI) were calculated using analysis of covariance with adjustment for baseline values of the RDQ and recruitment site.', 'At 6 weeks, both the corticosteroid+lidocaine group and the lidocaine-alone group had improvement in the RDQ scores (RDQ, RDQ using SIP weights, patient-prioritized RDQ) as compared with baseline scores (corticosteroid+lidocaine: -4.2 points, -4.1 points, -4.2; lidocaine-alone: -3.1 points,-2.9 points, and -3.1 points, respectively). However, there was no significant between-group difference in the RDQ or patient-prioritized RDQ (average treatment effect -1.0 points, 95% CI -2.1 to 0.1, P\u200a=\u200a0.07; -1.0 points, 95% CI -2.0 to 0.1, P\u200a=\u200a0.08 respectively). While the between-group difference of RDQ using SIP weights was statistically significant (average treatment effect -1.1, 95% CI -2.2 to -0.1, P\u200a=\u200a0.04), this was not clinically important.'] Does patient Priority Weighting of the Roland Morris Disability Questionnaire Change Results of the Lumbar Epidural Steroid Injections for Spinal Stenosis Trial?