How can a person's anger be controlled? The amygdala of the brain is related to the generation of anger. The frontal part of the brain can send signals to help control anger. Serotonin is the "messenger" that transmits this signal. Serotonin is a tryptophan synthesis in the human body, and Tryptophan is one of eight essential amino acids that the body cannot synthesize and can only be obtained from food. From this we can infer:. ["The level of human serotonin can indicate the individual's ability to manage emotions.", 'Patients with anger and mania can be treated with intravenous serotonin instead of sedatives.', 'Long-term lack of tryptophan in the diet may lead to poor mood control and easy anger.', 'Blocking the nerve transmission between the amygdala and the frontal lobe, making anger uncontrollable.']