['Stem cells have multiple ways of differentiating and restoring healing. This feature may recommend their usage for decreasing the incidence of anastomotic fistulas in the colon in case of colorectal malignancy.', 'To determine whether stem cells are improving digestive healing, we performed a literature review using as Mesh terms: "anastomotic leak", "stem cells", and "colonic anastomoses", followed by an observational analysis on 3 experimental studies.', 'We found that stem cells increase bursting pressure by an elevated rate of angiogenesis. In addition, the hydroxyproline content of the anastomoses is significantly increased in the stem cell group. The results concerning microscopic characteristics of digestive healing varied markedly between studies.'] Do stem cells improve the quality of colonic anastomoses - A systematic review?