['Medical students pursue different career paths based on a variety of factors. We sought to examine the impact of innate manual dexterity, both perceived and objective, on the career interests of medical students.', 'Third-year medical students from the University of California, Irvine were recruited for this study. Subjects completed a pretest questionnaire followed by assessment of gross and fine motor dexterity using the Purdue Pegboard test. A total of 6 independent trials were performed, 3 for each hand. The scores were recorded as an integer value between 0 and 25. A statistical analysis was performed using student t tests, the Fischer exact test, or the χ(2) test, where appropriate.', 'A total of 100 students completed the questionnaire while 58 completed the dexterity testing. Students interested in a surgical field (SF) were similar in handedness, gender, video game exposure, and learning style as those interested in a nonsurgical field (NSF). In the SF group, "personal skill set" was reported as the most common factor influencing career selection, and "interest in disease process/patient population" was reported most commonly by NSF students (p = 0.015). Although a perceived innate manual dexterity was higher among SF students compared with NSF students (p = 0.032), no significant objective differences were found in right hand, left hand, or combined dexterity scores.'] Do medical students pursuing surgical fields have no greater innate motor dexterity than those pursuing nonsurgical fields?