Fresh off their victory over the Packers, the Bills flew out to the RCA Dome for a Week 10 matchup with the Indianapolis Colts. Much like they did in the season-opener against the Patriots, Buffalo got off to a fast start in the first quarter with kicker Rian Lindell making a 22-yard field goal for the only score of the period. In the second quarter, however, Indianapolis struck back with Peyton Manning completing a 1-yard pass to Reggie Wayne. The Colts would follow that up with kicker Adam Vinatieri kicking a 31-yard FG. The Bills defense did make a stand, though, as Terrence McGee returned a fumble 68 yards for a touchdown. In the third quarter, Indianapolis regained the lead with Joseph Addai completing a 5-yard run. Buffalo would respond with Lindell making a30-yard FG. In the fourth quarter, the Bills drew closer with Lindell's 43-yard FG and had a chance to take the lead late in the game, let alone win, but a 41-yard try went wide right, not only dropping the Bills to 3-6, but last place in the AFC East.. How many losses did the BIlls come into this game with?