['Chronic kidney disease stage V is associated with a metabolic acidosis, a disturbance also observed in heavy alcohol consumption. Carbohydrate-deficient transferrin is considered the most accurate biomarker for identifying chronic alcohol abuse. We tested whether increased CDT results occurred in patients on dialysis therapy.', 'One hundred twenty-two samples from HD patients were analyzed by three different analytical methods and the results were compared with those obtained in 48 healthy volunteers.', 'On the basis of the upper 97.5th percentile, positive CDT results were found in 25.4%, 9.8% and 12.3% of the HD patients with particle-enhanced immunonephelometry, capillary electrophoresis and HPLC, respectively. A significant correlation between CDT values and transferrin concentration was found for the particle-enhanced immunonephelometric test (r: -0.311; p: 0.0009).'] Does false positive carbohydrate-deficient transferrin result in chronic hemodialysis patients related to the analytical methodology?