['To determine the effects of co-ingesting caffeine (CAF) and carbohydrate (CHO) on high-intensity intermittent sprints (HIS) performance and physiological responses.', 'Twelve active males underwent 4 interventions at least 7\xa0days apart in a randomized, double-blind, placebo-controlled, balanced trial. A meal contained 65\xa0% CHO was provided 2\xa0h before the HIS test. Participants ingested the placebo (PLA) or CAF (6\xa0mg\xa0kg(-1) BW) 1\xa0h before taking an HIS test, and ingested a PLA or CHO solution (0.8\xa0g\xa0kg(-1)\xa0BW) before undergoing the testing protocol. The HIS protocol comprised ten sets of 5\xa0×\xa04-s sprints on a cycle ergometer with a 2-min recovery between each set.', 'There was no significant difference between peak power output and mean power output between trials (p\xa0>\xa00.05). Compared with PLA, CAF\xa0+\xa0CHO resulted in a 5.2\xa0% reduction in total work, corresponding to a 24.7-25.7\xa0% increase in fatigue at the end stage of the HIS. The administration of CAF\xa0+\xa0CHO supplementation also resulted in an 11.1\xa0% increase in blood lactate, and elevated blood glucose concentrations throughout HIS testing compared with PLA (p\xa0<\xa00.05). Cortisol concentrations also increased with CAF\xa0+\xa0CHO intake compared with PLA; however, there was no significant effect of CAF\xa0+\xa0CHO supplementation on testosterone concentrations.'] Does co-ingestion of caffeine and carbohydrate after meal improve performance at high-intensity intermittent sprints with short recovery times?