['To evaluate the long-term voice characteristics and quality of life of early glottic cancer patients after definitive treatment.', 'Case series with chart review in a tertiary care medical center in Taiwan.', 'Forty-two consecutive patients who received radiation therapy (RT) or transoral laser microsurgery (TLM) for early glottic cancer over 12 months were evaluated for voice laboratory data and quality-of-life measurements.', 'Twenty-four patients received RT, and 18 underwent TLM. There was no difference between the two groups on acoustic and aerodynamic voice measures except for modal fundamental frequency in males. In the Functional Assessment of Cancer Therapy-Head and Neck survey, the TLM group had better communication than the RT group, but there were no differences in voice quality and strength. There was also no significant difference in the Voice Handicap Index 10 evaluation.'] Does transoral laser microsurgery elevate fundamental frequency in early glottic cancer?