['Mucosal ulcers and perforations of the nasal septum are very rare and may have several underlying causes. Contact allergy to steroids has been suggested as a possible aetiological factor in patients who develop perforations during topical steroid use.', 'We have identified 13 subjects with perforations of their nasal septum and concomitant topical nasal steroid use. In order to evaluate whether these patients had developed contact allergy to steroids they underwent patch testing with an extended steroid series.', 'None of the subjects displayed any positive reaction to the steroids.'] Are nasal septal perforations during treatment with topical nasal glucocorticosteroids generally not associated with contact allergy to steroids?