['The insulin-like growth factor (IGF) system has been known to play a critical role in tumor development and progression in many human cancers. However, the role of the IGF system in small intestinal carcinoma (SIC) has not been studied yet.', 'We evaluated the expression of IGF1 and IGF1 receptor (IFG1R) in a total of 194 cases of SIC.', 'IGF1 expression was associated with well/moderate differentiation, better survival, lower pT, lower stage and no lymph node metastasis. IGF1R was more diffusely and strongly expressed in tumors with lower pT and lower stage.'] Is expression of insulin-like growth factor 1 and insulin-like growth factor 1 receptor associated with the favorable clinicopathologic parameters in small intestinal carcinomas?