['Presently used prediction equations for maximal oxygen uptake are mostly derived from studies of western populations. However, the interracial differences are quite large when prediction equations for the Western-white population are applied to Asian-Indians. The present study was aimed at the initial development of a prediction equation for the healthy sedentary Indian participants using symptom limited graded incremental exercise testing and to compare the new regression equation to other published data.', 'Participants were staff and caregivers of patients from different states of India. All participants completed a maximal graded exercise test on a motorized treadmill at Christian Medical College, Vellore, Tamil Nadu to determine maximal oxygen uptake (VO(2)max).', 'Predictive equations for both men and women were obtained from multiple linear regression analysis and significant correlations were found for weight and height. The correlation coefficients of the new regression equations with measured VO(2)max of study population were R(2) = .511 for men and R(2) = .656 for women. These were compared with other published equations with differences ranging from 7% to 50% for men and 10% to 36% for women.'] Is maximal oxygen uptake lower for a healthy Indian population compared to white populations?