['Tet methylcytosine dioxygenase converts 5-mC to 5-hmC in DNA.', 'Ascorbate significantly and specifically enhances Tet-mediated generation of 5-hmC.'] Does ascorbate induce ten-eleven translocation ( Tet ) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine?