['Pemphigus is an autoimmune disease characterized by bullae, in which its chronicity and clinical manifestations generate alterations in the quality of life. In Brazil, the disease prevails in the states of the Midwest and Southeast. The study aimed to evaluate the profile and quality of life of patients with pemphigus in a Brazilian city, for the purposes of physiotherapeutic intervention.', 'The medical records of 15 institutionalized patients were analyzed, though only 7 volunteers underwent the initial and final interviews using the quality of life questionnaire SF-36. Between data collections, physical therapy exercises were applied over a four-month period. After this predetermined period the data were compared and analyzed quantitatively using the Med Calc E and the Student t test.', 'The 15 patients in treatment had a mean age of 40 years-old; 53.3% were melanoderm; 80% were men; 60% had contact with rural areas and 80% were from the southern region. The 7 patients who participated in the intervention showed a tendency for improvement in the areas assessed by the SF-36, except for vitality and social aspects.'] Does [ Physiotherapy intervention promote better quality of life for individuals with pemphigus ]?