Psychologist: Substance abuse, in a sense, is both genetic and learned. Some families may have a predisposition to depression or anxiety, which is known to increase an individual' s use of substances. Children who have parents who abused substances are four times more likely than the average person to abuse substances. The latter, however, is up for debate on whether this statistic is due to genetic predisposition or learned behavior. Which of the following is most strongly supported by the statements above? ['The proof for the genetic factor in substance abuse lies in the fact that children with parents who abused substances are four times more likely to use substances themselves.', 'The proof for the environmental factor in substance abuse lies in the fact that children with parents who abused substances are four times more likely to use substances themselves.', 'The proof for the genetic factor in substance abuse lies in the fact that there may be indirect genes within families, such as depression or anxiety, that increase the potential use for substance abuse.', 'Substance abuse is a learned behavior only; there is no "addictive" gene, and ttherefore we cannot consider the issue of substance abuse genetic in any way.']