Researchers in China have conducted clinical and multiple tests on animals and found that the traditional Chinese medicine Dogwood has anti-transplant immune rejection and treatment of autoimmune diseases. The results of the paper. Somewhat unfortunately, it took 6 weeks from the time the magazine received the paper to its publication. If this paper can be published as early as possible, many of these patients will avoid the disease within 6 weeks. Which of the following would weaken the above argument most? ['Oral dogwood may cause digestive discomfort.', 'The above medical journals were not sent to relevant experts for review before publishing this paper.', 'Only when dogwood is administered orally for more than 2 months can it exert immunosuppressive effects.', 'Dogwood has anti-transplant immune rejection and treatment of autoimmune diseases needs further confirmation.']