['Oxidative stress occurs only when exercise is exhaustive and is independent of the absolute duration of exercise. In this study the effects of short duration (03:50 +/- 00:06 min) high-intensity exhaustive exercise on lipid peroxidation and antioxidant status were examined.', 'A total of thirty-seven male university students (23.9+/-0.6 years old) participated in this study. None was involved in a regular training program before the study. Intensities of exercises were determined according to the maximum slope and speed they could run in Bruce Test Protocol which is used for determining V.O2max of the participants. Just before and after the high intensity exhaustive running exercise test, venous blood was collected and centrifuged to separate the plasma.', 'Lipid hydroperoxides (LOOH) did not change, glutathione peroxidase (GPx) decreased (2%) and catalase (CAT) increased (13%) at the pre and post exhaustive exercise test. These changes were not statistically significant (P>0.05). On the other hand, lactate dehydrogenase (LDH) levels significantly increased (31%) (P< 0.001).'] Does short duration exhaustive running exercise modify lipid hydroperoxide , glutathione peroxidase and catalase?