['To compare endocrine profiles and IVF outcomes after using GnRH agonists (GnRHa) to trigger final oocyte maturation in women with polycystic ovary syndrome (PCOS) with other hyper-responders.', 'Retrospective cohort study.', 'Academic center.', 'Forty women with PCOS and 74 hyper-responders without PCOS.', 'GnRHa trigger.', 'Number of oocytes.', 'Serum E2, LH, and P levels on the day of GnRHa trigger and the day after trigger did not differ significantly between groups. There were no significant differences in total number of oocytes or percent mature oocytes obtained between groups after controlling for age, antral follicle count, and total days of stimulation. The overall rate of no retrieval of oocytes after trigger was low (2.6%). Fertilization, implantation, clinical pregnancy, and live-birth rates were similar in the two groups. No patients developed ovarian hyperstimulation syndrome (OHSS).'] Is use of gonadotropin-releasing hormone agonist trigger during in vitro fertilization associated with similar endocrine profiles and oocyte measures in women with and without polycystic ovary syndrome?