['To verify whether heparin could enhance the stimulating effect of Tpo on megakaryocytopoiesis.', 'Megakaryocytic leukemia cell line M07e, human cord blood CD34+ cells and BALB/c mice were used in this study. The effects of heparin and/or Tpo on megakaryocytopoiesis were studied by [3H]-TdR incorporation assay, CFU-MK plasmic semi-solid culture and in vivo experiment in BALB/c mice.', 'Heparin could enhance the stimulating effect of Tpo on stimulating the proliferation of M-07e, the growth of CFU-MK from human cord blood CD34+ cells and in vivo megakaryocytopoiesis in mice.'] Does [ Heparin enhance the stimulating effect of thrombopoietin on megakaryocytopoiesis ]?