['Allergic asthma is one of the most common chronic inflammatory diseases of airways. Severe asthma may lead to hospitalization and death. Sesame oil is a natural product with anti-inflammatory property. However, the effect of sesame oil on allergic asthma has never been studied.', 'We investigate the effect of sesame oil on pulmonary inflammation in allergic asthma model.', 'Allergic airway inflammation was induced by sensitizing with two doses of 10\u2009mg ovalbumin (OVA) and then challenged with 1% OVA nebulizer exposure (1\u2009h/day) for 3 days. Sesame oil (0.25, 0.5, or 1\u2009mL/kg/day) was given orally 30\u2009min before each challenge. Samples were collected 24\u2009h after the last challenge.', 'Data showed that sesame oil inhibited pulmonary edema and decreased interleukin (IL)-1 β and IL-6 levels in bronchoalveolar lavage fluid in OVA-treated mice. Sesame oil also decreased pulmonary nitrite level, inducible nitric oxide synthase expression, and neutrophil infiltration induced by OVA. Further, sesame oil decreased serum IgE level in OVA-treated mice.'] Does sesame oil attenuate ovalbumin-induced pulmonary edema and bronchial neutrophilic inflammation in mice?