['Recent studies indicated that soluble OX40 ligand (OX40L) levels were increased in acute coronary syndrome. But the association between sOX40L and carotid intima-media thickness (IMT) has not been evaluated.', 'We measured plasma soluble OX40L (sOX40L) and Interleukin-10 (IL-10) levels in 35 patients with stable angina pectoris, 30 patients with risk factors of coronary artery disease, and 20 age and sex-matched controls. Carotid (IMT) was measured by B-mode ultrasound.', 'Plasma sOX40L levels were positively correlated with Carotid IMT (r = 0.376, P = 0.001) and inversely correlated with IL-10 (P = -0.394, P = 0.000). Multivariate linear regression analysis revealed that sOX40L (p = 0.019) was an independent predictor for Carotid IMT progression after adjusting for the classical cardiovascular risk factors.'] Is increased soluble OX40L associated with carotid intima-media thickness?