['It has been argued that carotid intima-media thickness (IMT) could better reflect an adaptive response of the vessel wall rather than being a marker of atherosclerosis. We explore this hypothesis by analyzing the ARTICO data.', 'The ARTICO study was designed to evaluate the prognostic value of the pathological ankle-brachial index (ABI) for the emergence of new vascular events in patients who have suffered a noncardioembolic stroke. Collected variables were as follows: vascular risk factors, mean waist perimeter, quantification of carotid IMT, characteristics of carotid plaques, ABI, and presence of microalbuminuria.', "A total of 591 patients with a complete carotid evaluation were available. There was no correlation between ABI and IMT (Spearman's, p NS). Logistic regression revealed that pathological ABI correlated significantly only with internal carotid artery stenosis\u2009greater than or equal to\u200950% (OR [odds ratio] 2.80, 1.66-4.71, P\u2009<\u2009.01) and peripheral artery disease (OR 3.33, 1.63-6.78, P\u2009<\u2009.01). However, multivariate regression analysis demonstrated that carotid IMT was independently associated with age (OR 1.05, 95% confidence interval [CI] 1.02-1.09, P\u2009<\u2009.01), hypertension (OR 1.83, 95% CI 1.02-3.26, P\u2009=\u2009.04), waist circumference (OR 1.03, 95% CI 1.01-1.05, P\u2009<\u2009.01), and microalbuminuria (OR 2.02, 95% CI 1.22-3.35, P\u2009<\u2009.01)."] Is carotid Intima-Media Thickness Associated with Markers of Atherosclerosis in Stroke Patients?