Laboratory experiments and clinical trial observations show that some commonly used antibacterial drugs should be taken on an empty stomach, because after taking a meal, food may affect the absorption of the drug, or make the drug utilization rate significantly lower. Which of the following most support the above assertions:. ['antibacterial drugs, not irritating to the stomach and intestines, can be taken on an empty stomach.', 'antibacterials taken on an empty stomach are just a small part of all antibacterials.', 'people want to increase the efficacy of drugs when taking them.', 'In the past, the use of antibacterial drugs was obviously unreasonable.']