[': The objective of this study was to determine the safety and efficacy of botulinum toxin A in ameliorating refractory sialorrhea and improving quality of life in patients with amyotrophic lateral sclerosis.', ': Six patients with bulbar ALS received bilateral parotid gland injections of botulinum toxin A.', ': No adverse effects occurred. Tissue use decreased in 5 of 7 patients at a dose of 10 units and in 3 of 4 patients at a dose of 20 units. Self-reported quality of life did not change in most.'] Are parotid gland injections of botulinum toxin a effective in treating sialorrhea in amyotrophic lateral sclerosis?