['Ghrelin plays an important role in the growth processes in children, additionally, it regulates appetite. The aim of the study was to assess ghrelin and insulin-like growth factor type I (IGF-I) concentrations in children with idiopathic short stature (ISS), dependent on nutritional status.', 'The study group included 116 children, aged 10.6\u200a±\u200a3.5 years (mean\u200a±\u200aSD), with ISS [height below -2.0 standard deviation scores (SDS), maximal growth hormone (GH) secretion during two GH-stimulating tests - over 10\u200ang/ml]. In each child, fasting ghrelin, IGF-I, insulin-like growth factor binding protein 3 (IGFBP-3), glucose, insulin, lipids, leptin, adiponectin and resistin concentrations were assessed. The IGF-I/IGFBP-3 molar ratio was calculated to determine the IGF-I bioavailability. According to body mass index SDS calculated for height age (BMI SDS for HA), the children were divided into 3 groups: poorly nourished (thin), normal and obese. The control group consisted of 19 healthy children, aged 11.0\u200a±\u200a3.5 years, with normal body weight and height.', 'Ghrelin concentration was significantly higher in short, thin children than in short, obese children (1458.3\u200a±\u200a798.5 vs. 917.2\u200a±\u200a303.0\u200apg/ml; p\u200a<\u200a0.005). In turn, IGF-I/IGFBP-3 molar ratio was significantly lower in short, thin children than in short, obese children (0.16\u200a±\u200a0.06 vs. 0.28\u200a±\u200a0.15; p\u200a<\u200a0.005).'] Is nutritional Status in Short Stature Children Related to Both Ghrelin and Insulin-like Growth Factor I Concentrations?