Studies have shown that an increase in the amount of lipoprotein in the blood will enhance the absorption of excess cholesterol in human tissues. Some people can significantly increase the amount of lipoprotein in the blood through physical exercise and weight loss. Based on this text, what is the most appropriate conclusion we can draw? ['Some people have lowered cholesterol in their blood through physical exercise, these people must be fat.', 'People who do not exercise regularly, especially fat people, have the highest risk of high cholesterol in the blood.', 'Physical exercise and weight loss are the most effective ways to lower high cholesterol in the blood.', 'Some people lower cholesterol in their blood through physical exercise and weight loss.']