['Early-life immune deviation is suspected in the inception of atopic disease.', 'To investigate the association between cord blood chemokines and the subsequent development of atopic biomarkers and clinical end-points during the first 6\xa0years of life.', 'The Th1-associated chemokines CXCL10 and CXCL11 and the Th2-associated chemokines CCL17 and CCL22 were assessed in cord blood of asymptomatic at-risk newborn children from the Copenhagen Prospective Study on Asthma in Childhood (COPSAC(2000) ) birth cohort and associated with the longitudinal development of biomarkers and clinical end-points of asthma, eczema, and allergic rhinitis during the first 6\xa0years of life.', 'Cord blood CCL22 levels were significantly associated to total-IgE levels measured at four time-points during the first 6\xa0years of life; overall odds ratio, 1.54 [CI, 1.25-1.89; P\xa0<\xa00.0001]. CXCL10 and CXCL11 were not associated with development of any atopic disorders or biomarkers.'] Do cord blood Th2-related chemokine CCL22 levels associate with elevated total-IgE during preschool age?