Coming off their bye week, the Rams went home for a Week 10 duel with the undefeated New Orleans Saints. After a scoreless first quarter, Saints running back Reggie Bush got a 3-yard touchdown run to open the scoring, but the Rams would answer when quarterback Marc Bulger found wide receiver Donnie Avery on a 29-yard touchdown pass. Although New Orleans retook the lead with quarterback Drew Brees' 15-yard touchdown pass to Bush, St. Louis would close out the half with running back Steven Jackson's 2-yard touchdown run. The Saints would deliver a huge strike in the third quarter as wide receiver Courtney Roby returned the second half's opening kickoff 97 yards for a touchdown, yet the Rams would keep it close with kicker Josh Brown's 32-yard field goal. In the fourth quarter, New Orleans would increase their lead with Brees' 27-yard touchdown pass to wide receiver Robert Meachem. St. Louis tried to rally as Bulger completed a 19-yard touchdown pass to Avery (with a failed 2-point conversion), but the Saints' defense would prevent any further progress.. Which team allowed the most second half points?