All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders Mr. Ryan struck out 5,714 batters in his career. All-Time list All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders number 5 on this list All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders second highest total number 5 on this list most strikeouts All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All-Time list All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders strikeout record of 5,714 All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders All Time Strikeout Leaders second highest total All Time Strikeout Leaders All Time Strikeout Leaders all time