http://www.ncbi.nlm.nih.gov/pubmed/8614291 found in a 1996 study scientists subjected lab rats to pure nicotine Long-term effects of inhaled nicotine Citation received monumental doses of nicotine for two years a 1996 study found in a 1996 study http://www.ncbi.nlm.nih.gov/pubmed/8614291 http://www.ncbi.nlm.nih.gov/pubmed/8614291 http://www.ncbi.nlm.nih.gov/pubmed/8614291 Long-term effects of inhaled nicotine http://www.ncbi.nlm.nih.gov/pubmed/8614291 indicated Waldum et al study http://www.ncbi.nlm.nih.gov/pubmed/8614291 ex1 inhaling pure nicotine