peer-reviewed phase II phase II trial peer-reviewed confidence interval relative risk (RR) systematic review peer-reviewed systematic review cohort study systematic review meta-analysis peer-reviewed control randomised controlled trials (RCTs) peer-reviewed peer-reviewed peer-reviewed case-control study odds ratio peer-reviewed confidence interval phase III randomised controlled trials peer-reviewed peer-reviewed odds ratio cohort study confounders peer-reviewed peer-reviewed confidence interval cohort study prospective peer-reviewed confidence interval (CI) case-control study case-control study cohort study randomised controlled trial controls phase two trials cohort study blinding statistically significant case-control study peer-reviewed cross-sectional study cohort study cohort study peer reviewed prospective odds ratio peer-reviewed confounders case-control study control group confidence interval systematic review peer-reviewed observational studies prospective odds ratio peer-reviewed case-control study odds ratio [OR] the controls peer-reviewed odds ratio systematic review peer-reviewed case-control study time-trend study controls cohort studies confidence interval controls peer-reviewed peer-reviewed peer-reviewed randomised controlled trial odds ratio case series cohort study cohort study case-control study prospective cohort study case-control study confidence interval [CI] peer-reviewed confidence intervals confidence interval confidence interval peer-reviewed prospective case-control study peer-reviewed odds ratio Observational studies confidence interval (CI) controls peer-reviewed nested case control studies peer-reviewed peer-reviewed phase III randomised controlled trials control group peer-reviewed peer-reviewed peer-reviewed peer-reviewed peer-reviewed observational study narrative review peer-reviewed peer-reviewed phase I randomised controlled trial narrative review controls confidence interval controls peer-reviewed systematic review hazard ratio cohort study absolute risk peer-reviewed peer-reviewed systematic review peer-reviewed peer-reviewed non-randomised case-control study peer-reviewed peer-reviewed statistically significant cohort cohort studies peer-reviewed systematic review cross-sectional study case-crossover cross-sectional studies peer-reviewed systematic review randomised controlled trials prospective cross-sectional study peer-reviewed case-control confidence interval Phase III odds ratio cross-sectional study peer-reviewed confidence interval [CI] odds ratio confidence interval Phase III systematic review peer-reviewed narrative review peer-reviewed peer-reviewed cohort study peer-reviewed Phase III phase I peer-reviewed peer-reviewed cohort study case-control study prospective study confidence interval [CI] peer-reviewed peer-reviewed peer-reviewed systematic review cohort study odds ratio controls meta-analysis case-control study controls odds ratio peer-reviewed peer-reviewed peer-reviewed phase I peer-reviewed cohort studies controls peer-reviewed confounders peer-reviewed odds ratio peer-reviewed odds ratio [OR] confidence intervals peer-review odds ratio case-control study non-randomised peer-reviewed control group randomised controlled trials control cohort study randomised controlled trial systematic review case-control study phase II trial peer-reviewed peer-reviewed prospective cross-sectional study peer-reviewed phase II peer-reviewed prospective study randomised controlled trial systematic review systematic review peer-reviewed peer-reviewed peer-reviewed odds ratio statistically significant confidence interval case-control study confounders phase II trial prospective study confidence interval peer-reviewed controls confidence intervals hazard ratio phase III randomised controlled trials confidence interval peer-reviewed cohort studies controls peer-reviewed confounders retrospective study cross-sectional study peer-reviewed peer-reviewed confounders odds ratio peer-reviewed peer-reviewed control peer-reviewed case-control study peer-reviewed controls randomised controlled trial systematic review peer-reviewed controls peer-reviewed cross-sectional confidence interval [CI] peer-reviewed peer-reviewed randomised controlled trial case-control case-control study hazard ratio systematic review narrative review cross-sectional study statistically significant confidence interval Phase III double-blind Phase II confidence intervals case-crossover peer-reviewed case-control study randomised controlled trial peer-reviewed peer-reviewed controls peer-reviewed peer-reviewed confidence interval systematic review prospective study meta-analysis meta-analysis randomised controlled trials meta-analysis narrative review peer-reviewed randomised controlled trial confidence interval randomised controlled trial (RCT) (meta-analysis) peer-reviewed confounders confounding factors peer-reviewed peer-reviewed cohort study case-control study prospective peer-reviewed confidence intervals cohort study peer-reviewed control group narrative review peer-reviewed cross-sectional blinding systematic review cross-sectional study meta-analysis systematic review case-control study hazard ratio peer-reviewed odds ratio Phase III odds ratio peer-reviewed hazard ratio controls cohort study randomised controlled trial phase III randomised controlled trials case-crossover peer-reviewed peer-reviewed randomised controlled trials (RCTs) cross-sectional study odds ratio peer-reviewed confidence intervals case-control study cohort study peer-reviewed cohort analysis peer-reviewed cohort study randomised controlled trial confidence intervals confidence interval peer-reviewed randomised controlled trial peer-reviewed peer-reviewed controls peer-reviewed relative risks blinding non-randomised specificity randomised controlled trial odds ratio statistically significant peer-reviewed systematic review peer-reviewed peer-reviewed observational studies confidence intervals cohort study confidence interval peer-reviewed peer-reviewed cross-sectional retrospective study control group systematic review peer-reviewed prospective study case series phase III randomised controlled trials meta-analysis control confidence interval peer-reviewed case-control study cohort study systematic review non-randomised peer-reviewed controls meta-analyses relative risk (RR) peer-reviewed peer-reviewed odds ratio peer-reviewed control groups peer-reviewed systematic review peer-reviewed peer-reviewed relative risk (RR) relative risk (RR) peer-reviewed confidence interval odds ratio phase I peer-reviewed controls significant increase peer-reviewed control group peer-reviewed peer-reviewed peer-reviewed peer-reviewed peer-reviewed systematic review peer-reviewed confidence interval phase II cross-sectional study cross-sectional observational study observational studies peer-reviewed odds ratio cross-sectional study peer-reviewed peer-reviewed peer-reviewed confidence interval phase II trial peer reviewed control groups peer-reviewed confidence interval [CI] confounding retrospective study cross-sectional study peer-reviewed peer-reviewed cohort study odds ratio controls peer-reviewed peer-reviewed confidence interval [CI] randomised controlled trial non-randomised randomised controlled trial statistically significant confounders peer-reviewed peer-reviewed confidence interval peer-reviewed peer-reviewed peer-reviewed peer-reviewed odds ratio confidence interval peer-reviewed peer-reviewed meta-analysis phase 1 trial odds ratio peer-reviewed confidence interval [CI] confounders peer-reviewed confidence interval confidence interval cohort study confidence interval [CI] cross-sectional study peer-reviewed sensitivity peer-reviewed confidence interval phase II odds ratio confounding cohort study randomised controlled trials (RCTs) retrospective peer-reviewed prospective cohort study confidence interval peer-reviewed systematic review peer-reviewed randomised controlled trial case-crossover peer-reviewed meta-analysis odds ratio prospective cohort study non-randomised absolute risk confidence intervals case-crossover confidence interval odds ratio systematic review systematic review cohort study confidence intervals phase II trial systematic review phase II Phase III control group randomised controlled trial peer-reviewed controls case-control study confidence interval (CI) peer-reviewed prospective study confidence interval randomised controlled trials peer-reviewed confidence interval confounders cohort study confidence interval [CI] peer-reviewed peer-reviewed confidence intervals confidence interval cohort studies systematic review cross-sectional analysis confidence interval [CI] randomised controlled trial peer-reviewed confidence interval systematic review meta-analysis observational studies cohort study peer-reviewed peer-reviewed peer-reviewed peer-reviewed systematic review randomised controlled trial confidence interval confidence interval phase II trial odds ratio confounders case-control study cohort study peer-reviewed phase II trial confidence interval peer-reviewed systematic review peer-reviewed peer-reviewed peer-reviewed peer-reviewed non-randomised confidence interval peer-reviewed cohort study control groups peer-reviewed confidence interval odds ratios peer-reviewed confounders systematic review systematic review peer-reviewed peer-reviewed specificity cohort study confounders statistically significant randomised controlled trial Phase III confidence interval confidence interval [CI] cohort study randomised controlled trial phase II trial systematic review cross sectional study peer-reviewed confidence interval peer-reviewed confidence interval confidence interval peer-reviewed confidence intervals peer-reviewed case-control study confounders confidence intervals peer-reviewed case-control study peer-reviewed prospective odds ratio randomised controlled trials peer-review case-cohort study odds ratio randomised controlled trial observational studies randomised controlled trial odds ratio prospective peer-reviewed peer-reviewed cohort studies randomised controlled trial peer-reviewed randomised controlled trial odds ratio peer-reviewed cohort study confidence interval randomised controlled trial peer-reviewed confidence interval [CI] blinding phase II peer-reviewed peer-reviewed cohort study peer-reviewed randomised controlled trial systematic review systematic review peer-reviewed relative risk [RR] peer-reviewed phase II systematic review peer-reviewed peer-reviewed laboratory and animal research controls randomised controlled trial confidence interval peer-reviewed randomised controlled trials confounding factors odds ratio case-control studies systematic review peer-reviewed peer-reviewed peer-reviewed confidence intervals blinding double-blind confidence interval cross-sectional study case-control study confounding case-control study case-crossover peer-reviewed peer-reviewed case-crossover peer-reviewed peer-reviewed controls cross-sectional study prospective study confidence interval peer-reviewed cohort study phase 1 trial phase II peer-reviewed retrospective study odds ratio peer-reviewed peer-reviewed case-control study peer-reviewed controls odds ratio cross-sectional observational study randomised control trial confidence interval [CI] confidence interval statistically significant peer-reviewed cross-sectional studies cohort study prospective cohort study peer-reviewed confidence interval controls confidence interval [CI] case-control study non-randomised peer-reviewed case-control study peer-reviewed confidence interval peer-reviewed cohort study peer-reviewed peer-reviewed peer-reviewed peer-reviewed odds ratio phase I peer-reviewed cohort study peer-reviewed controls peer-reviewed cohort study retrospective studies control peer-reviewed cohort study peer-reviewed odds ratio randomised controlled trial control group systematic review retrospective studies cross-sectional studies cohort study peer-reviewed peer-reviewed confidence interval peer-reviewed systematic review odds ratio peer-reviewed peer-reviewed peer-reviewed confidence interval (CI) randomised controlled trial time-trend study peer-reviewed peer-reviewed case-control study peer-reviewed case-control study odds ratio [OR] peer-reviewed peer-reviewed case-control confounders peer-reviewed peer-reviewed absolute risk time-trend study peer-reviewed peer-reviewed peer-reviewed control systematic review prospective study peer-reviewed prospective study peer-reviewed phase I randomised controlled trial case-control study systematic review peer-reviewed systematic review case control studies confidence interval confidence interval odds ratio confidence interval statistically significant odds ratio double-blind confidence interval phase II confidence interval (CI) peer-reviewed peer-reviewed randomised controlled trials (RCTs) systematic review peer-reviewed peer-reviewed confidence interval [CI] peer-reviewed peer-reviewed peer-reviewed peer-reviewed confidence intervals odds ratio peer-reviewed odds ratio cohort study hazard ratio prospective randomised controlled trial controls confidence interval [CI] peer-reviewed case-control study meta-analysis confidence interval non-randomised peer-reviewed confidence intervals peer-reviewed controls systematic review peer-reviewed confidence interval confounders peer-reviewed confidence interval peer-review control group peer-reviewed confidence interval [CI] peer-reviewed peer-reviewed phase II peer-reviewed confidence interval odds ratio odds ratio peer-reviewed peer-reviewed controls cohort study narrative review controls confidence interval Phase III randomised controlled trial confidence interval control group retrospective study confidence interval peer review confidence intervals cohort studies peer-reviewed confidence interval case-control study case-crossover case-control study time-trend study peer-reviewed cross-sectional study cohort study peer-reviewed confidence interval meta-analysis peer-reviewed confounders odds ratio peer-reviewed peer-reviewed confounders confidence interval peer-reviewed systematic review confidence interval peer-reviewed peer-reviewed phase I peer-reviewed confidence intervals controls confidence interval peer-reviewed peer-reviewed prospective confidence interval systematic review confidence interval systematic review observational study peer-reviewed confidence interval peer-reviewed cross-sectional study Confidence interval control group peer-reviewed case-control study peer-reviewed cohort studies case-crossover peer-reviewed peer-reviewed cohort study systematic review systematic review cohort study case-crossover confounders meta-analysis peer-reviewed prospective odds ratio case-control study confidence interval odds ratio statistically significant observational studies peer-reviewed collecting data prospectively peer-reviewed cohort studies peer-reviewed randomised controlled clinical trial confidence interval peer-reviewed confounding variables controls peer-reviewed peer-reviewed peer-reviewed cross-sectional study confounders peer-reviewed case-control study confounders peer-reviewed confidence interval controls control groups peer-reviewed randomised controlled trial odds ratio confidence interval confidence interval meta-analysis phase II trial non-randomised phase I odds ratio peer-reviewed peer-reviewed control peer-reviewed systematic review systematic review time-trend study case-crossover cohort study non-randomised time-trend study randomised controlled trial controls confounders peer-reviewed peer-reviewed peer-reviewed narrative review peer-reviewed systematic review randomised controlled trial case-control study odds ratio phase 3 peer-reviewed peer-reviewed peer-reviewed confidence interval confidence interval confidence interval retrospective studies confidence interval peer-reviewed observational studies prospective study statistically significant statistically significant peer-reviewed systematic review prospective cohort study phase II peer-reviewed Phase III peer-reviewed non-randomised trial retrospective study peer-reviewed systematic review peer-reviewed case-control observational studies cohort study