The model ascribes them to a multitude of factors, including strong nominal US demand, heightened investor risk aversion as well as the prospect of higher US inflation and tighter monetary conditions. Portfolio flows to EMEs have declined significantly in the course of 2018, largely as a result of increased investor sensitivity towards EME asset markets and rising protectionist pressures. After a spell of strong and stable foreign purchases of debt and equity instruments issued by sovereigns and corporates in EMEs throughout 2017, aggregate portfolio flows to EMEs have dipped notably since February 2018. Global investors started to reassess the potential negative effects of a tighter US monetary policy and a stronger dollar on financial conditions in EMEs and the downside risks to global growth stemming from mounting protectionist pressures. EMEs appear to be particularly exposed to these risks. Several EMEs borrow heavily in international markets and are affected by the tightening of US dollar funding conditions. Moreover, EMEs are generally more open to trade than advanced economies, relying on policies geared towards free trade to support economic growth. This box aims to disentangle the role of these global factors in driving the recent slowdown in portfolio flows to EMEs from country-specific vulnerabilities, which may have exacerbated the impact of global risks. The intensification of trade tensions this year has raised concerns about the potential adverse impact on global growth and asset prices. So far, the isolated effects of introducing tariffs on selected goods on asset prices have been adverse mainly for specific companies that rely heavily on international trade. At the same time, global financial markets have overall been fairly resilient to the announcements and implementation of tariff measures. This special feature finds that an escalation of trade tensions could trigger a global repricing in asset markets. For the euro area, asset prices would be strongly affected in the event of a full-blown global trade war, in which all countries impose tariffs on each other, while the impact of a regionally contained trade dispute escalation would be rather subdued. By extending a standard set of financial stability indicators with indicators capturing spillover and contagion risks, this special feature proposes a financial stability risk index (FSRI) that has predictive power for the near-term risk of deep recessions. It is shown that the empirical performance of the index benefits from combining a large set of macro-financial indicators and, notably, that the information content of the spillover and contagion risk indicators is important. This special feature presents a tractable, transparent and broad-based cyclical systemic risk indicator (CSRI) that captures risks stemming from domestic credit, real estate markets, asset prices, external imbalances and cross-country spillovers. The CSRI increases on average several years before the onset of systemic financial crises and its level is highly correlated with measures of crisis severity. Model estimates suggest that high values of the CSRI contain information about large declines in real GDP growth three to four years down the road, as it precedes shifts in the entire distribution of future real GDP growth and especially of its left tail. Given its timely signals, the CSRI is a useful analytical tool for macroprudential policymakers to complement other existing analytical tools. The cost of subordinated bank debt in the euro area is low and may be susceptible to repricing. Euro area bank bond yields and spreads have narrowed significantly since mid-2016, reaching levels last observed prior to the global financial crisis. The reductions have been particularly noticeable in the markets for subordinated bonds.57 Against this background, this box first evaluates whether there are indications that the prices of these bonds may be vulnerable to a correction. It then assesses the potential financial implications stemming from a spread reversal in euro area subordinated bank bonds. The box focuses in particular on the holders of these instruments and examines the sectors that may be particularly vulnerable to a turnaround in this market. The market for NPLs in Europe has become more active in recent years. The total amount and volume of transactions has continuously increased in the last three years, although part of the increase in volumes can be attributed to just a few large transactions. Italy and Spain account for the majority of the market turnover. However, the geographical scope of NPL markets in the euro area has also widened, with transactions starting in Greece in 2017 and in Cyprus in 2018. At the same time, market activity in more mature NPL markets, such as Ireland, has weakened against the backdrop of a diminishing supply of NPLs. Improving operating efficiency is key if euro area banks are to raise their profitability to sustainable levels. The FSR has been consistently reporting on the basis of accounting indicators, such as the cost-to-income ratio (CIR) and the cost-to-assets ratio, that, on aggregate, euro area banks’ cost efficiency has deteriorated somewhat since 2010. While the improving cyclical environment is supporting bank profitability, raising it to levels that can ensure banks are able to provide financing to the real economy in a sustainable manner would benefit from improving their cost efficiency. The market for leveraged loans is significant and recent developments may be generating financial stability risks.25 In both Europe and the United States, the markets for leveraged loans issued by non-financial corporates are about five times larger than high-yield bond markets. In 2017 US leveraged loan issuance rose well above its pre-crisis levels, with gross issuance, depending on methodology and data source, estimated at between €500 billion and €1 trillion, while EU issuance, estimated at between €120 billion and €320 billion, is around the previous highs recorded in 2007 and 2014. This box assesses potential financial stability concerns related to the rapidly growing market for crypto-assets. Crypto-assets (e.g.