 Prior research lacks the investigation of how machine learning can be applied to a big-data platform to ensure an informed  and judicious prescribing of opioids .
<clarity>  Prior research lacks the investigation of how machine learning can be applied to a big-data platform to ensure an informed  and judicious prescribing of opioids .
 Little is known about how machine learning can be applied to a big-data platform to ensure an informed and judicious prescribing of opioids .