 Endeavoring toward a transferable, predictive coarse-grained explicit-chain model for biomolecular LLPS, we used the N-terminal intrinsically disordered region (IDR) of the DEAD-box helicase Ddx4  as a test case to conduct extensive multiple-chain simulations to assess the roles of electrostatic, hydrophobic, cation-\pi, and aromatic interactions in sequence-specific phase behaviors.
<meaning-changed>  Endeavoring toward a transferable, predictive coarse-grained explicit-chain model for biomolecular LLPS, we used the N-terminal intrinsically disordered region (IDR) of the DEAD-box helicase Ddx4  as a test case to conduct extensive multiple-chain simulations to assess the roles of electrostatic, hydrophobic, cation-\pi, and aromatic interactions in sequence-specific phase behaviors.
 Endeavoring toward a transferable, predictive coarse-grained explicit-chain model for biomolecular condensates underlain by liquid-liquid phase separation (LLPS), we conducted multiple-chain simulations of the N-terminal intrinsically disordered region (IDR) of the DEAD-box helicase Ddx4 as a test case to conduct extensive multiple-chain simulations to assess the roles of electrostatic, hydrophobic, cation-\pi, and aromatic interactions in sequence-specific phase behaviors.