 These backbones maintain all relevant information while displaying a substantially decreased number of interconnections and, hence, they become a useful tool to extract main metabolic highways and so to unveil important biological information.
<clarity>  These backbones maintain all relevant information while displaying a substantially decreased number of interconnections and, hence, they become a useful tool to extract main metabolic highways and so to unveil important biological information.
 These backbones maintain all relevant information while displaying a substantially decreased number of interconnections and, hence, they become a useful tool to extract relevant metabolic routes which unveil important biological information.