 At the same time, a comparative analysis of  E. coli backbones in different media leads to the identification of pathways sensitive to environmental changes.
<meaning-changed>  At the same time, a comparative analysis of  E. coli backbones in different media leads to the identification of pathways sensitive to environmental changes.
 At the same time, a comparative analysis of the backbone of E. coli backbones in different media leads to the identification of pathways sensitive to environmental changes.