 For genotyping of microorganisms for medical diagnosis, or other purposes, scientists may use a wide variety of DNA profiling techniques, such as PCR, PFGE and MLST . A complication of this broad variety of pre-WGS techniques is the difficulty to standardize between techniques, laboratories and microorganisms, which may be overcome using the complete DNA code of the genome generated by WGS techniques. For straight forward diagnostic identificationthe WGS information of a microbiological sample is fed into a global genomic database and compared using BLAST procedures to the genomes already present in the database.
<clarity>  For genotyping of microorganisms for medical diagnosis, or other purposes, scientists may use a wide variety of DNA profiling techniques, such as PCR, PFGE and MLST . A complication of this broad variety of pre-WGS techniques is the difficulty to standardize between techniques, laboratories and microorganisms, which may be overcome using the complete DNA code of the genome generated by WGS techniques. For straight forward diagnostic identificationthe WGS information of a microbiological sample is fed into a global genomic database and compared using BLAST procedures to the genomes already present in the database.
 For genotyping of microorganisms for medical diagnosis, or other purposes, scientists may use a wide variety of DNA profiling techniques, such as PCR, PFGE and MLST . A complication of this broad variety of pre-WGS techniques is the difficulty to standardize between techniques, laboratories and microorganisms, which may be overcome using the complete DNA code of the genome generated by whole genome sequencing. For straightforward diagnostic identification, the whole genome sequencing information of a microbiological sample is fed into a global genomic database and compared using BLAST procedures to the genomes already present in the database.