 We illustrate their use in a cost-effectiveness analysis of a treatment using a previously published testbed cSTM. Both time-independent cSTM where transition probabilities are constant over time  and time-dependent cSTM where transition probabilities vary over time are represented.
<clarity>  We illustrate their use in a cost-effectiveness analysis of a treatment using a previously published testbed cSTM. Both time-independent cSTM where transition probabilities are constant over time  and time-dependent cSTM where transition probabilities vary over time are represented.
 We illustrate their use in a cost-effectiveness analysis. With this example, we illustrate both time-independent cSTM where transition probabilities are constant over time and time-dependent cSTM where transition probabilities vary over time are represented.