 Among the 6\% of European coeliacs that do not have DQ2.5 (cis or trans) or DQ8 (encoded by the haplotype DQA1*03:DQB1*0302), 4\% have the DQ2.2 isoform, and the remaining 2\% lack DQ2 or DQ8. 250px|Illustration of deamidated α-2 gliadin's 33mer, amino acids 56–88, showing the overlapping of three varieties of T-cell epitope Membrane leaking permits peptides of gliadin that stimulate two levels of  immune response: the innate response, and the adaptive (T-helper cell mediated ) response.
<fluency>  Among the 6\% of European coeliacs that do not have DQ2.5 (cis or trans) or DQ8 (encoded by the haplotype DQA1*03:DQB1*0302), 4\% have the DQ2.2 isoform, and the remaining 2\% lack DQ2 or DQ8. 250px|Illustration of deamidated α-2 gliadin's 33mer, amino acids 56–88, showing the overlapping of three varieties of T-cell epitope Membrane leaking permits peptides of gliadin that stimulate two levels of  immune response: the innate response, and the adaptive (T-helper cell mediated ) response.
 Among the 6\% of European coeliacs that do not have DQ2.5 (cis or trans) or DQ8 (encoded by the haplotype DQA1*03:DQB1*0302), 4\% have the DQ2.2 isoform, and the remaining 2\% lack DQ2 or DQ8. 250px|Illustration of deamidated α-2 gliadin's 33mer, amino acids 56–88, showing the overlapping of three varieties of T-cell epitope Membrane leaking permits peptides of gliadin that stimulate two levels of immune response: the innate response, and the adaptive (T-helper cell-mediated ) response.