 The approach precludes the need for expert knowledge in proposing candidate reactions, such that the inference is autonomous and applicable to new systemsfor which there is no existing empirical knowledge to propose reaction pathways .
<meaning-changed>  The approach precludes the need for expert knowledge in proposing candidate reactions, such that the inference is autonomous and applicable to new systemsfor which there is no existing empirical knowledge to propose reaction pathways .
 The approach precludes the need for expert knowledge in proposing candidate networks and addresses the curse of dimensionality in complex systems .