 SARS-Cov-2 degrades ACE2 and thus worsens lung injury, causes vasoconstriction, thrombotic problems, and exacerbated inflammatory response .
<meaning-changed>  SARS-Cov-2 degrades ACE2 and thus worsens lung injury, causes vasoconstriction, thrombotic problems, and exacerbated inflammatory response .
 Moreover, many manifestations of severe CoViD-19, such as severe lung injury, causes vasoconstriction, thrombotic problems, and exacerbated inflammatory response .