 We have recently shown that spark termination emerges as collective behavior (synchronized closings) of Ca release channels (RyRs) that is identical to synchronization of spin orientation in ferromagnets described by a phase transition in Ising model . Objective: We employed the Ising approach to investigate and classify mechanisms of spark termination failure and Ca leak. Methods and Results: The key parametersdetermining whether spark termination succeeds or fails are SR Ca and RyR opening/closing rates. They define analogues of magnetic field h and the inverse temperature (\beta) in Ising model\beta*\beta* \beta*  . Sparks terminate via a phase transition known as "hpolarity reversal" and the leak emerges when hfails to change its sign.
<clarity>  We have recently shown that spark termination emerges as collective behavior (synchronized closings) of Ca release channels (RyRs) that is identical to synchronization of spin orientation in ferromagnets described by a phase transition in Ising model . Objective: We employed the Ising approach to investigate and classify mechanisms of spark termination failure and Ca leak. Methods and Results: The key parametersdetermining whether spark termination succeeds or fails are SR Ca and RyR opening/closing rates. They define analogues of magnetic field h and the inverse temperature (\beta) in Ising model\beta*\beta* \beta*  . Sparks terminate via a phase transition known as "hpolarity reversal" and the leak emerges when hfails to change its sign.
 We have recently shown that spark termination emerges as collective behavior (synchronized closings) of Ca release unit (CRU) reveal sharp transitions resulting in Ca leak. The emergence of leak is closely mapped mathematically to the Ising model from statistical mechanics. The system steady-state behavior is determined by two aggregate parameters: the analogues of magnetic field h and the inverse temperature (\beta) in Ising model\beta*\beta* \beta* . Sparks terminate via a phase transition known as "hpolarity reversal" and the leak emerges when hfails to change its sign.