 We also discovered that women are at a 60\% risk increase of DDI when compared to men , while only having a 6\% co-administration risk increase. Analysis of the DDI co-occurrence network reveals which DDI pairs are most associated with the observed greater DDI risk for females, demonstrating that contraception and hormone therapy are not the main culprits of the gender disparity, which is maximized after the reproductive years .
<meaning-changed>  We also discovered that women are at a 60\% risk increase of DDI when compared to men , while only having a 6\% co-administration risk increase. Analysis of the DDI co-occurrence network reveals which DDI pairs are most associated with the observed greater DDI risk for females, demonstrating that contraception and hormone therapy are not the main culprits of the gender disparity, which is maximized after the reproductive years .
 We also discovered that women are at a 60\% risk increase of DDI when compared to men ; the increase becomes 90\% when only major DDI are considered .