 As an application of our methods , we analyze the large-scale regulatory network of E. colinumerically: We identify the most determinative nodes and show that a small set of those reduces the overall uncertainty of network states significantly.
<fluency>  As an application of our methods , we analyze the large-scale regulatory network of E. colinumerically: We identify the most determinative nodes and show that a small set of those reduces the overall uncertainty of network states significantly.
 As an application of our methods , we analyze the large-scale regulatory network of E. colinumerically: We identify the most determinative nodes and show that a small subset of those reduces the overall uncertainty of network states significantly.