Uruguay faced Portugal in the second match of the Last 16 at  . Portuguese captain Cristiano Ronaldo had an attempt for a goal in the 6th minute from 's assist, but it was saved. A minute later, Uruguayan striker  scored a header from  's assist, giving the South Americans an early lead. Just before the half-time whistle, Cavani had an opportunity to double the lead from 's assist but missed it. The first half ended with Uruguay leading 1–0. Ten minutes into the second half,  equalised for Portugal, scoring a header from 's assist. In the 62nd minute, Cavani scored a goal from 's assist, restoring Uruguay's one-goal advantage. Cavani was later substituted off in the 74th minute due to injury.  's attempt for an equaliser in the injury time was saved and Uruguay won the match 2–1.
Uruguay faced Portugal in the second match of the Last 16 at Sochi . Portuguese captain Cristiano Ronaldo had an attempt for a goal in the 6th minute from 's assist, but it was saved. A minute later, Uruguayan striker Edinson Cavani scored a header from Luis Suárez 's assist, giving the South Americans an early lead. Just before the half-time whistle, Cavani had an opportunity to double the lead from 's assist but missed it. The first half ended with Uruguay leading 1–0. Ten minutes into the second half, Pepe equalised for Portugal, scoring a header from 's assist. In the 62nd minute, Cavani scored a goal from 's assist, restoring Uruguay's one-goal advantage. Cavani was later substituted off in the 74th minute due to injury. Ricardo Quaresma 's attempt for an equaliser in the injury time was saved and Uruguay won the match 2–1.
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Sochi
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Edinson Cavani
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Luis Suárez
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Pepe
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Ricardo Quaresma