Role in SARS-CoV-2 infection (COVID-19) The host-cell-expressed basigin (CD147) may bind spike protein of SARS-CoV-2 and possibly be involved in host cell invasion. Subsequently, meplazumab, a humanized anti-CD147 antibody, was tested in patients with SARS-CoV-2 pneumonia. However, some of these claims have been challenged by another group of scientists who found no  role for basigin in either binding the viral spike protein or promoting lung cell infection.
Role in SARS-CoV-2 infection (COVID-19) The host-cell-expressed basigin (CD147) may bind spike protein of SARS-CoV-2 and possibly be involved in host cell invasion. Subsequently, meplazumab, a humanized anti-CD147 antibody, was tested in patients with SARS-CoV-2 pneumonia. Some of these claims have been challenged by another group of scientists who found no evidence of a direct role for basigin in either binding the viral spike protein or promoting lung cell infection.
R
However, some
Some
A
evidence of a direct