The occurrence of sleep passed through the evolutionary sieve and is widespread in animal species. Sleep is known to be beneficial to cognitive and mnemonic tasks, while chronic sleep deprivation is detrimental. Despite the importance of the phenomenon, a theoretical and computational approach demonstrating the underlying mechanisms is still lacking. In this paper, we show interesting effects of deep-sleep-like slow oscillation activity on a simplified thalamo-cortical model which is trained to encode, retrieve and classify images of handwritten digits. If spike-timing-dependent-plasticity (STDP) is active during slow oscillations, a differential homeostatic process is observed . It is characterized by both a specific  enhancement of connections among groups of neurons associated to instances of the same class (digit) and a simultaneous down-regulation of stronger synapses created by the training. This is reflected in a URLanization of post-sleep internal representations. Such effects favour higher performance in retrieval and classification tasks and create hierarchies of categories in integrated representations. The model leverages on the coincidence of top-down contextual information with bottom-up sensory flow during the training phase and on the integration of top-down predictions and bottom-up thalamo-cortical pathways during deep-sleep-like slow oscillations. Also, such mechanism hints at possible applications to artificial learning systems.
The occurrence of sleep passed through the evolutionary sieve and is widespread in animal species. Sleep is known to be beneficial to cognitive and mnemonic tasks, while chronic sleep deprivation is detrimental. Despite the importance of the phenomenon, a theoretical and computational approach demonstrating the underlying mechanisms is still lacking. In this paper, we show interesting effects of deep-sleep-like slow oscillation activity on a simplified thalamo-cortical model which is trained to encode, retrieve and classify images of handwritten digits. During slow oscillations, spike-timing-dependent-plasticity (STDP) produces a differential homeostatic process . It is characterized by both a specific unsupervised enhancement of connections among groups of neurons associated to instances of the same class (digit) and a simultaneous down-regulation of stronger synapses created by the training. This is reflected in a URLanization of post-sleep internal representations. Such effects favour higher performances in retrieval and classification tasks and create hierarchies of categories in integrated representations. The model leverages on the interaction between of top-down cortico-thalamic predictions and bottom-up thalamo-cortical projections during deep-sleep-like slow oscillations. Such mechanism hints at possible applications to artificial learning systems.
R
If
During slow oscillations,
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is active during slow oscillations,
produces
D
is observed
A
unsupervised
R
performance
performances
R
coincidence
interaction between
R
contextual information with bottom-up sensory flow during the training phase and on the integration of top-down
cortico-thalamic
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pathways
projections
R
Also, such
Such