The continuous research of new diagnostical methods , early, low invasive and much efficient is orienting the technological research toward the use of bio-integrated devices and in particular sensors, able to use the excellent ability of proteins to selectively react to a specific stimulus, in a fast, reproducible and reversible way. To explore these specific features, a theoretical/computational model called INPA (impedance network protein analogue) is used . The specific characteristic of this approach is to give in a glance a description of the protein not lingering on the complex details of its biochemialc nature but instead privileging its activity .
The need of new diagnostic methods satisfying, as an early detection, a low invasive procedure and a cost-efficient value, is orienting the technological research toward the use of bio-integrated devices , in particular bio-sensors. The set of know-why necessary to achieve this goal is wide, from biochemistry to electronics and is summarized in an emerging branch of electronics, calledproteotronics. Proteotronics is here here applied to state a comparative analysis of the electrical responses coming from type-1 and type-2 opsins. In particular, the procedure is used as an early investigation of a recently discovered family of opsins, the proteorhodopsins activated by blue light, BPRs. The results reveal some interesting and unexpected similarities between proteins of the two families, suggesting the global electrical response are not strictly linked to the class identity .
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continuous research of new diagnostical methods , early, low invasive and much efficient
need of new diagnostic methods satisfying, as an early detection, a low invasive procedure and a cost-efficient value,
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and in particular sensors, able to use the excellent ability of proteins to selectively react to a specific stimulus, in a fast, reproducible and reversible way. To explore these specific features, a theoretical/computational model called INPA (impedance network protein analogue) is used . The specific characteristic of this approach is to give in a glance a description of the protein not lingering on the complex details of its biochemialc nature but instead privileging its activity
, in particular bio-sensors. The set of know-why necessary to achieve this goal is wide, from biochemistry to electronics and is summarized in an emerging branch of electronics, called
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proteotronics
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. Proteotronics is here here applied to state a comparative analysis of the electrical responses coming from type-1 and type-2 opsins. In particular, the procedure is used as an early investigation of a recently discovered family of opsins, the proteorhodopsins activated by blue light, BPRs. The results reveal some interesting and unexpected similarities between proteins of the two families, suggesting the global electrical response are not strictly linked to the class identity