Enterovirus D68 (EV-D68) is a member of the Picornaviridae family, an enterovirus. First isolated in California in 1962 and once considered rare, it has been on a worldwide upswing in the 21st century. It is suspected of causing a polio-like disorder called acute flaccid myelitis  . Acute flaccid myelitis The virus is one cause of acute flaccid myelitis  a rare muscle weakness, usually due to polio , since two California children  who tested positive for the virus  had paralysis of one or more limbs reaching peak severity within 48 hours of onset. "Recovery of motor function was poor at 6-month follow-up." As of October 2014, the CDC was investigating 10 cases of paralysis and/or cranial dysfunction in Colorado and other reports around the country, coinciding with the increase in enterovirus D68 activity. As of October 2014 it was believed that the actual number of cases might be 100 or more. As of 2018 the link of EV-D68 and the paralysis is strong, meeting six Bradford Hill criteria fully and two partially.Peter Dockrill. We May Finally Know The Cause of Polio-Like Illness Paralysing Children Around The World 23 January 2018, Sciencealert The CDC recently issued a statement on 17 October 2018 claiming "Right now, we know that poliovirus is not the cause of these AFM cases. CDC has tested every stool specimen from the AFM patients, none of the specimens have tested positive for the poliovirus." In 2019, the CDC has published that AFM is caused by Enterovirus D68.
Enterovirus D68 (EV-D68) is a member of the Picornaviridae family, an enterovirus. First isolated in California in 1962 and once considered rare, it has been on a worldwide upswing in the 21st century. It is suspected of causing a polio-like disorder called acute flaccid myelitis (AFM) . Acute flaccid myelitis The virus is one cause of acute flaccid myelitis , a rare muscle weakness, usually due to polio . In 2014, the cases of two California children were described who tested positive for the virus and had paralysis of one or more limbs reaching peak severity within 48 hours of onset. "Recovery of motor function was poor at 6-month follow-up." As of October 2014, the CDC was investigating 10 cases of paralysis and/or cranial dysfunction in Colorado and other reports around the country, coinciding with the increase in enterovirus D68 activity. As of October 2014 it was believed that the actual number of cases might be 100 or more. As of 2018 the link of EV-D68 and the paralysis is strong, meeting six Bradford Hill criteria fully and two partially.Peter Dockrill. We May Finally Know The Cause of Polio-Like Illness Paralysing Children Around The World 23 January 2018, Sciencealert The CDC recently issued a statement on 17 October 2018 claiming "Right now, we know that poliovirus is not the cause of these AFM cases. CDC has tested every stool specimen from the AFM patients, none of the specimens have tested positive for the poliovirus." In 2019, the CDC has published that AFM is caused by Enterovirus D68.
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