Proline and its higher homolog pipecolic acid affect the secondary structure of protein. D-alpha-amino acid - L-alpha-amino acid sequence can induce beta hairpin. It suggested that acyclic secondary amino acids are more flexible than cyclic secondary amino acids in protein by Replacement of Pipecolic Acid by N-Methyl-L-alanine in Efrapeptin C.
Proline and its higher homolog pipecolic acid affect the secondary structure of protein. D-alpha-amino acid - L-alpha-amino acid sequence can induce beta hairpin. It suggested that acyclic secondary amino acids are more flexible than cyclic secondary amino acids in protein by replacement of pipecolic acid by N-methyl-L-alanine in efrapeptin C.
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Replacement of Pipecolic Acid by N-Methyl-L-alanine in Efrapeptin
replacement of pipecolic acid by N-methyl-L-alanine in efrapeptin