Potassium Spatial Buffering Glial cells, once believed to have a passive role in CNS, are active regulators of numerous functions in the brain, including clearance of the neurotransmitter from the synapses, guidance during neuronal migration, control of neuronal synaptic transmission, and maintaining ideal ionic environment for active communications between neurons in central nervous system.Kozoriz, M. G., D. C. Bates, et al. (2006). "Passing potassium with and without gap junctions." Journal of Neuroscience 26(31): 8023-8024. Kir Channel The high permeability of glial cell membranes to potassium ions is a result of expression of high densities of potassium-selective channels with high open-probability at resting membrane potentials. Kir channels, potassium inward-rectifying channels, allow passage of potassium ions inward much more readily than outward. They also display a variable conductance that positively correlates with extracellular potassium concentration: the higher the potassium concentration outside the cell, the higher the conductance. Panglial Syncytium Notes See also%DIFDELCMD < %DIFDELCMD < %%% External resources
Potassium spatial buffering Glial cells, once believed to have a passive role in CNS, are active regulators of numerous functions in the brain, including clearance of the neurotransmitter from the synapses, guidance during neuronal migration, control of neuronal synaptic transmission, and maintaining ideal ionic environment for active communications between neurons in central nervous system.Kozoriz, M. G., D. C. Bates, et al. (2006). "Passing potassium with and without gap junctions." Journal of Neuroscience 26(31): 8023-8024. Kir channel The high permeability of glial cell membranes to potassium ions is a result of expression of high densities of potassium-selective channels with high open-probability at resting membrane potentials. Kir channels, potassium inward-rectifying channels, allow passage of potassium ions inward much more readily than outward. They also display a variable conductance that positively correlates with extracellular potassium concentration: the higher the potassium concentration outside the cell, the higher the conductance. Panglial syncytium %DIFDELCMD < %DIFDELCMD < %%% References
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Spatial Buffering
spatial buffering
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Channel
channel
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Syncytium
syncytium
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Notes
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See also
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External resources
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