alt= Informationsgrafik Rapid Transfer Port| mini|Alpha-Port-Transferschleuse: Informationsgrafik zum Rapid Transfer Port (RTP) A Rapid Transfer Port (RTP for short, also alpha-beta port system) is a transfer system that allows material to be rapidly transferred into and out of an isolator without contamination. mini|verweis=Special:FilePath/Edelstahl-Beta-Behälter.jpg|alt=Beta Container 316L|Beta-Transfer-Container aus Edelstahl The alpha port is integrated into the isolator, the mobile unit of the transfer system, the beta port (a stainless steel, plastic or aluminum container) can be docked.  It is possible to open the door of the alpha port from the inside via glove intervention and thus to introduce material into the beta container. Undocking of the beta container can only be done when the door of the alpha port is closed. The hermetic seal is not broken during the process. Types  Rapid Transfer Ports are used for contamination-free material transfer into and out of barrier systems such as RABS or isolators. They are considered the safest method for bidirectional transfer in aseptic or toxic work areas without restriction or violation of sterility. The basic design of RTP systems is often the same regardless of the manufacturer. Major differences can only be found in the degree of customization and in additional applications, such as whether solid or liquid substances are introduced. The alpha flange with door is permanently integrated into the isolator wall or embedded into the floor of the containment. alt=Schnittmodell eines Liquid-Beta-Transfer-Containers|mini|Schnittmodell eines Liquid-Beta-Transfer-Containers The alpha flange consists of a stainless steel flange and a door made mainly of plastic, which is attached to a hinge. Both parts are closed with a latch and fitted with a seal. In addition, the alpha flange is equipped with a mechanical safety mechanism that prevents the door from opening in the absence of a container. Beta port  The second main component is the beta assembly, consisting of a canister with the beta flange and the beta door, which is sealed to the flange with a gasket. A 60° rotation docks the beta transfer container to the alpha port. alt=Schnittmodell eines Alpha-Port|mini|Schnittmodell eines Alpha-Ports Once the alpha and beta components are connected, they form a closed unit. The leak tightness is ensured by the lip seals of the newly created unit, which can be opened without interrupting the sterility containment.  When the alpha and beta ports are connected by bayonet catches, the interlock is released, and the door can be opened inside the isolator. This allows rapid transfer of material between the container and containment without compromising cleanroom integrity. mini|Alpha-Ports an einem Isolator|alternativtext= A safety system prevents inappropriate use of the transfer lock and ensures a high level of personal and product protection. The door of the alpha port can only be opened when the beta port is correctly docked.  Stainless steel beta containers can be sterilized in an autoclave with a sterile filter connected. The air is replaced by saturated steam, cooled and then extracted from the container as condensate. Containers made of PE cannot be autoclaved and are usually sterilized with gas or by gamma irradiation.  Drawer systems installed in the beta container allow the container to be loaded and unloaded safely. Instruments and components such as Petri dishes, vials or stoppers can thus be transferred as required for the process. mini|alt=Transfer von Stopfen und Verschlüssen von pharmazeutischen Primärverpackungen|Transfer von Stopfen und Verschlüssen von pharmazeutischen Primärverpackungen The RTP was developed for aseptic transfer. To maintain cleanroom status, the tightness of isolators and RABS systems is part of the GMP requirements. Transfer systems are critical points in terms of tightness and must therefore withstand tightness tests in the test procedure, in addition to other critical parameters. alt=Einbringen von Petrischalen mittels eines Rail Schienensystems|mini|Einbringen von Petrischalen mittels eines Rail-Schienensystems
alt= Information graphic explaining a Rapid Transfer Port| Information graphic explaining a Rapid Transfer Port A Rapid Transfer Port (RTP for short, also alpha-beta port system) is a transfer system that allows material to be rapidly transferred into and out of an isolator without contamination. The alpha port is integrated into the isolator, the mobile unit of the transfer system, the beta port (a stainless steel, plastic or aluminum container) can be docked. alt=Stainless steel beta container |Stainless steel beta container It is possible to open the door of the alpha port from the inside via glove intervention and thus to introduce material into the beta container. Undocking of the beta container can only be done when the door of the alpha port is closed. The hermetic seal is not broken during the process. Types alt=Cutaway view of a liquid beta transfer container|Cutaway view of a liquid beta transfer container Rapid Transfer Ports are used for contamination-free material transfer into and out of barrier systems such as RABS or isolators. They are considered the safest method for bidirectional transfer in aseptic or toxic work areas without restriction or violation of sterility. The basic design of RTP systems is often the same regardless of the manufacturer. Major differences can only be found in the degree of customization and in additional applications, such as whether solid or liquid substances are introduced. The alpha flange with door is permanently integrated into the isolator wall or embedded into the floor of the containment. The alpha flange consists of a stainless steel flange and a door made mainly of plastic, which is attached to a hinge. Both parts are closed with a latch and fitted with a seal. In addition, the alpha flange is equipped with a mechanical safety mechanism that prevents the door from opening in the absence of a container. Beta port alt=Cutaway View of an Alpha Port|Cutaway View of an Alpha Port The second main component is the beta assembly, consisting of a canister with the beta flange and the beta door, which is sealed to the flange with a gasket. A 60° rotation docks the beta transfer container to the alpha port. Once the alpha and beta components are connected, they form a closed unit. The leak tightness is ensured by the lip seals of the newly created unit, which can be opened without interrupting the sterility containment. alt=Alpha ports on an isolator|Alpha ports on an isolator When the alpha and beta ports are connected by bayonet catches, the interlock is released, and the door can be opened inside the isolator. This allows rapid transfer of material between the container and containment without compromising cleanroom integrity. A safety system prevents inappropriate use of the transfer lock and ensures a high level of personal and product protection. The door of the alpha port can only be opened when the beta port is correctly docked. alt=Transfer of stoppers and closures from pharmaceutical primary packaging|Transfer of stoppers and closures from pharmaceutical primary packaging Stainless steel beta containers can be sterilized in an autoclave with a sterile filter connected. The air is replaced by saturated steam, cooled and then extracted from the container as condensate. Containers made of PE cannot be autoclaved and are usually sterilized with gas or by gamma irradiation. alt=Insertion of Petri dishes by means of a drawer system|Insertion of Petri dishes by means of a drawer system Drawer systems installed in the beta container allow the container to be loaded and unloaded safely. Instruments and components such as Petri dishes, vials or stoppers can thus be transferred as required for the process. The RTP was developed for aseptic transfer. To maintain cleanroom status, the tightness of isolators and RABS systems is part of the GMP requirements. Transfer systems are critical points in terms of tightness and must therefore withstand tightness tests in the test procedure, in addition to other critical parameters. 
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mini|Alpha-Port-Transferschleuse: Informationsgrafik zum
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mini|verweis=Special:FilePath/Edelstahl-Beta-Behälter.jpg|alt=Beta Container 316L|Beta-Transfer-Container aus Edelstahl
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alt=Stainless steel beta container |Stainless steel beta container
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alt=Cutaway view of a liquid beta transfer container|Cutaway view of a liquid beta transfer container
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alt=Schnittmodell eines Liquid-Beta-Transfer-Containers|mini|Schnittmodell eines Liquid-Beta-Transfer-Containers
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alt=Cutaway View of an Alpha Port|Cutaway View of an Alpha Port
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alt=Schnittmodell eines Alpha-Port|mini|Schnittmodell eines Alpha-Ports
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alt=Alpha ports on an isolator|Alpha ports on an isolator
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mini|Alpha-Ports an einem Isolator|alternativtext=
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alt=Transfer of stoppers and closures from pharmaceutical primary packaging|Transfer of stoppers and closures from pharmaceutical primary packaging
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alt=Insertion of Petri dishes by means of a drawer system|Insertion of Petri dishes by means of a drawer system
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mini|alt=Transfer von Stopfen und Verschlüssen von pharmazeutischen Primärverpackungen|Transfer von Stopfen und Verschlüssen von pharmazeutischen Primärverpackungen
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alt=Einbringen von Petrischalen mittels eines Rail Schienensystems|mini|Einbringen von Petrischalen mittels eines Rail-Schienensystems