Limiting factors The factors affecting V̇O2 are often divided into supply and demand. Supply is the transport of oxygen from the lungs to the mitochondria ( including lung diffusion, stroke volume , blood volume, and capillary density of the skeletal muscle) while demand is the rate at which the mitochondria can reduce oxygen in the process of oxidative phosphorylation. Of these, the supply factor is often considered to be the limitingone . However, it has also been argued that while trained subjects are probably supply limited, untrained subjects can indeed have a demand limitation. Factors that affect V̇O2 max are age, sex, fitness and training, altitude, among others . V̇O2 max can be a poor predictor of performance in runners due to variations in running economy and fatigue resistance during prolonged exercise. Cardiac output, pulmonary diffusion capacity, oxygen carrying capacity, and the peripheral limitations of muscle diffusion capacity, mitochondrial enzymes, and capillary density are all examples of V̇O2 max determinants. The body works as a system. If one of these factors is sub-par, then the whole system loses its normal capacity to function properly .
Limiting factors The factors affecting V̇O2 may be separated into supply and demand. Supply is the transport of oxygen from the lungs to the mitochondria ( combining pulmonary function, cardiac output , blood volume, and capillary density of the skeletal muscle) while demand is the rate at which the mitochondria can reduce oxygen in the process of oxidative phosphorylation. Of these, the supply factors may be more limiting . However, it has also been argued that while trained subjects are probably supply limited, untrained subjects can indeed have a demand limitation. General characteristics that affect V̇O2 max include age, sex, fitness and training, and altitude . V̇O2 max can be a poor predictor of performance in runners due to variations in running economy and fatigue resistance during prolonged exercise. The body works as a system. If one of these factors is sub-par, then the whole system 's normal capacity is reduced .
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including lung diffusion, stroke volume
combining pulmonary function, cardiac output
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factor is often considered to be the limitingone
factors may be more limiting
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Factors
General characteristics
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include
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altitude, among others
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Cardiac output, pulmonary diffusion capacity, oxygen carrying capacity, and the peripheral limitations of muscle diffusion capacity, mitochondrial enzymes, and capillary density are all examples of V̇O2 max determinants.
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loses its normal capacity to function properly
's normal capacity is reduced