wanglab/gogpt-training-data huggingface dataset:
Protein: Regulator of G-protein signaling 9-binding protein (RGS9-anchoring protein) (Q8MJG0)
Organism: Bos taurus (Bovine)
Function: Regulator of G protein-coupled receptor (GPCR) signaling in phototransduction. Participates in the recovery phase of visual transduction via its interaction with RGS9-1 isoform. Acts as a membrane-anchor that mediates the targeting of RGS9-1 to the photoreceptor outer segment, where phototransduction takes place. Enhances the ability of RGS9-1 to stimulate G protein GTPase activity, allowing the visual signal to be terminated on the physiologically time scale. It also controls the proteolytic stability of RGS9-1, probably by protecting it from degradation (By similarity).
Subcellular location: Membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}.
Interaction partners:
- Regulator of G-protein signaling 9
- Regulator of G protein signaling 11
- Guanine nucleotide-binding protein subunit beta-5
- Regulator of G-protein signaling 7-binding protein
- Regulator of G-protein signaling 7
- Protein kinase C alpha type
- Regulator of G protein signaling 6
- Rhodopsin
- Rod outer segment membrane protein 1
Sequence:
MAKEECKALLDALNKATACYHHLVLTIGGSADSQNLREELQKTRQKAQELAVAIRLRLTAPLRDRSLGAEERAEFERLWVAFSGCLDLLEADMRRALALSTEFPLQEPRRPLVRTGVEGGATGVAARALSVRSLRHEAHRDFDVEDLHQLEREILQVGEMIQDMEMKVNVPRWTVQARQAAGAELLSSASAGVSSVGGVSVEQRTGPCDLSKAKAATIFSAVLLAAVALAVCVAKLS
Protein: Protein Turandot C (Q8IN43)
Organism: Drosophila melanogaster (Fruit fly)
Function: A humoral factor that may play a role in stress tolerance.
Subcellular location: Secreted {ECO:0000269|PubMed:11409894, ECO:0000305}.
Interaction partners:
- Protein Turandot M
- Protein Turandot X
Sequence:
MNASISLLCLALLLISPFCLGYSDEERESDSLRVAEIIRTSNDAESKINRTQELLDIFRRLTPTLSPEQREKIERSIQEHTDEILIDGVPSQGGRKTKYVGKILSPVAQGLAVGFFEELGGSLSRLFTG
Protein: Citrate synthase (F8VTT8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MALLTAAARLLGTKNASCLVLAARHASASSTNLKDILADLIPKEQARIKTFRQQHGKTVVGQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKAKGGEEPLPEGLFWLLVTGHIPTEEQLIYEDSMDLIAKLPCV
Protein: Sensory/regulatory protein RpfC (EC 2.7.13.3) (P0C0F6)
Organism: Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
Function: Hybrid sensor kinase that regulates diverse biological functions through two distinct molecular mechanisms (By similarity). At low cell density, the extracellular concentration of the diffusible signaling factor (DSF) is below a threshold, and unphosphorylated RpfC is involved in the negative regulation of DSF synthesis, via direct interaction with the DSF synthase RpfF. Interaction prevents synthesis of DSF, which remains at a basal level. This activity does not involve the phosphorelay mechanism and is not dependent on RpfG. Is also member of the two-component regulatory system RpfG/RpfC, which is involved in the perception and response to DSF, which is essential for cell-cell signaling (By similarity). At high cell density, the level of extracellular DSF increases and binding of DSF to the sensor region of RpfC causes autophosphorylation of RpfC, which results in the release of RpfF and the activation of RpfG via a four-step phosphorelay (By similarity). Activation of RpfG leads to the positive regulation of biofilm dispersal and the production of virulence factors (By similarity).
Subcellular location: Cell inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes at the cell poles. {ECO:0000250|UniProtKB:P0C0F7}.
Interaction partners:
- Response regulator
- RpfF protein
- Long-chain-fatty-acid--CoA ligase
- Sensory/regulatory protein RpfC
- histidine kinase
- Chemotaxis protein CheA
- histidine kinase
- histidine kinase
- histidine kinase
- histidine kinase
Sequence:
MKSPLPWLKRRLSGRADSEHAQNLIRIIITTLFISYLGWRYQHTHGDTLMATWLILVGELLVSLGLMVAILLRPQVSHTRRLIGMLLDYTCTGAIMAIQGEPASPLYAVCMWVTIGNGLRYGSNYLRAATAMGSLCFLGAILISPYWKANPYLSWGLLLGLIAVPLYFDSLLRAMTRAVREARHANQAKSRFLANMSHEFRTPLNGLSGMTEVLATTRLDAEQKECLNTIQASARSLLSLVEEVLDISAIEAGKIRIDRRDFSLREMIGSVNLILQPQARGRRLEYGTQVADDVPDLLKGDTAHLRQVLLNLVGNAVKFTEHGHVLLRVTRVSGSAEDAVRLRFDVEDTGIGVPMDMRPRLFEAFEQADVGLSRRYEGTGLGTTIAKGLVEAMGGSIGFKENQPSGSVFWFELPMAIGEPLKSSTVRVPTGALVDAPEELESSNIIAFSNPFLRHRARVRSMRMLVADDHEANRMVLQRLLEKAGHKVLCVNGAEQVLDAMAEEDYDAVIVDLHMPGMNGLDMLKQLRVMQASGMRYTPVVVLSADVTPEAIRACEQAGARAFLAKPVVAAKLLDTLADLAVSTRQLATPATTVQVATSFEGVLDSSVLDELAALGMGEEFERQFVRQCLDDAQNCVGDIERDGTCSDWEQLRESAHALRGVASNLGLAQVASSGGELMRMADWQLQAEWRLRLSTLREQLKAGKDALDARVQGVKDGECSPRSNE
Protein: Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ER-Golgi intermediate compartment 32 kDa protein) (ERGIC-32) (Q969X5)
Organism: Homo sapiens (Human)
Function: Possible role in transport between endoplasmic reticulum and Golgi.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:15308636}; Multi-pass membrane protein {ECO:0000269|PubMed:15308636}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:15308636}; Multi-pass membrane protein {ECO:0000269|PubMed:15308636}. Golgi apparatus membrane {ECO:0000269|PubMed:15308636}; Multi-pass membrane protein {ECO:0000269|PubMed:15308636}. Note=Cycles between the endoplasmic reticulum and the Golgi.
Interaction partners:
- Surfeit locus protein 4
- 5-taurinomethyluridine-[tRNA] synthase subunit GTPB3, mitochondrial
- Protein ERGIC-53
- Surfeit locus protein 2
Sequence:
MPFDFRRFDIYRKVPKDLTQPTYTGAIISICCCLFILFLFLSELTGFITTEVVNELYVDDPDKDSGGKIDVSLNISLPNLHCELVGLDIQDEMGRHEVGHIDNSMKIPLNNGAGCRFEGQFSINKVPGNFHVSTHSATAQPQNPDMTHVIHKLSFGDTLQVQNIHGAFNALGGADRLTSNPLASHDYILKIVPTVYEDKSGKQRYSYQYTVANKEYVAYSHTGRIIPAIWFRYDLSPITVKYTERRQPLYRFITTICAIIGGTFTVAGILDSCIFTASEAWKKIQLGKMH
Protein: RNA-binding protein MIP6 (MEX67-interacting protein 6) (P38760)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Eukaryotic initiation factor 4F subunit p150
- Eukaryotic initiation factor 4F subunit p130
- Protein PES4
- Eukaryotic peptide chain release factor GTP-binding subunit
- PAB1-binding protein 1
- ATP-dependent helicase NAM7
- Uncharacterized protein YER187W
Sequence:
MPNSHGNVLNNISLNSKQNPRSISKSCPNDKDARQKSFKTISAQALVRVQGAGYKLGDVKLKDAEVKEKNSLKKYDCKNATQEKKEQEQVFEKTVAKGSVQKYITKTSKTNSLFIGNLKSTVTEEMLRKIFKRYQSFESAKVCRDFLTKKSLGYGYLNFKDKNDAESARKEFNYTVFFGQEVKIMPSMKNTLFRKNIGTNVFFSNLPLENPQLTTRSFYLIMIEYGNVLSCLLERRKNIGFVYFDNDISARNVIKKYNNQEFFGNKIICGLHFDKEVRTRPEFTKRKKMIGSDIVIEDELLASNNLSDNARSKTILVKNLPSDTTQEEVLDYFSTIGPIKSVFISEKQANTPHKAFVTYKNEEESKKAQKCLNKTIFKNHTIWVGPGKDKPVHNQIGTNKKTKVYLKNLSFNCNKEFISQLCLQEKIRFSEIKITNYNSLNWTFCGHVECFSRSDAERLFNILDRRLIGSSLVEASWSKNNDNILNEIDYDDGNNNENYKKLINISSMMRFRTQELSAHQKGLTSQFQQVVSPFSSYSNSYTNMNSLVATPMKPHPAFNLITNTVDEKLHQPKRTKQENAEILESLKKIINRNLQRISISGLNKEENLRSISEFIFDVFWEHDSERLSHFLLMTNTSLESQKILQKQVTRAAESLGFTV
Protein: Nucleotidyl transferase AbiEii/AbiGii toxin family protein (P71626)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- AbiEi antitoxin C-terminal domain-containing protein
- AbiEi antitoxin C-terminal domain-containing protein
- Nucleotidyl transferase AbiEii/AbiGii toxin family protein
- Uncharacterized protein
- Nucleotidyl transferase AbiEii/AbiGii toxin family protein
Sequence:
MAGLTRALVARHALGRAEAYDAALLDVAQDHLLYLLSQTVQFGDNRLVFKGGTSLRKCRLGNVGRFSTDLDFSAPDDEVVLEVCELIDGARVGGFEFGVQSTRGDGRHWQLRVRHTELGEPRIVASVEFARRPLALPSELLAFIQLPIHKAYGFGLPTLPVVAEAEACAEKLARYRRVALARDLYDLNHFASRTIDEPLVRRLWVLKVWGDVVDDRRGTRPLRVEDVLAARSEHDFQPDSIGVLTRPVAMAAWEARVRKRFAFLTDLDADEQRWAACDERHRREVENALAVLRS
Protein: Ninein-like protein (Q9Y2I6)
Organism: Homo sapiens (Human)
Function: Involved in the microtubule organization in interphase cells. Overexpression induces the fragmentation of the Golgi, and causes lysosomes to disperse toward the cell periphery; it also interferes with mitotic spindle assembly. May play a role in ovarian carcinogenesis.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:16254247, ECO:0000269|PubMed:26485514}. Cytoplasm {ECO:0000269|PubMed:16254247}. Note=In interphase cells, NINL is transported to the centrosomes by the dynein-dynactin motor complex (PubMed:16254247). During centrosome maturation, PLK1 directly phosphorylates NINL resulting in its release into the cytoplasm (PubMed:16254247).
Interaction partners:
- Serine/threonine-protein kinase PLK1
- Lebercilin
- Dynactin subunit 1
- Usherin
- Tubulin gamma-1 chain
- [F-actin]-monooxygenase MICAL3
- BICD family-like cargo adapter 1
- Cytoplasmic dynein 1 heavy chain 1
- Gamma-tubulin complex component 4
- Protein Hook homolog 3
Sequence:
MDEEENHYVSQLREVYSSCDTTGTGFLDRQELTQLCLKLHLEQQLPVLLQTLLGNDHFARVNFEEFKEGFVAVLSSNAGVRPSDEDSSSLESAASSAIPPKYVNGSKWYGRRSRPELCDAATEARRVPEQQTQASLKSHLWRSASLESVESPKSDEEAESTKEAQNELFEAQGQLQTWDSEDFGSPQKSCSPSFDTPESQIRGVWEELGVGSSGHLSEQELAVVCQSVGLQGLEKEELEDLFNKLDQDGDGKVSLEEFQLGLFSHEPALLLESSTRVKPSKAWSHYQVPEESGCHTTTTSSLVSLCSSLRLFSSIDDGSGFAFPDQVLAMWTQEGIQNGREILQSLDFSVDEKVNLLELTWALDNELMTVDSAVQQAALACYHQELSYQQGQVEQLARERDKARQDLERAEKRNLEFVKEMDDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAERELFWEQAHRQRAALEWDVGRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKDLEFVLKDKLEPQSAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRHSPSWSPDGRRRQLPGLGPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYEREIAALKRNFEKERKDMEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGPEPEQMGLAPCCTQALCGLALRHHSHLQQIRREAEAELSGELSGLGALPARRDLTLELEEPPQGPLPRGSQRSEQLELERALKLQPCASEKRAQMCVSLALEEEELELARGKRVDGPSLEAEMQALPKDGLVAGSGQEGTRGLLPLRPGCGERPLAWLAPGDGRESEEAAGAGPRRRQAQDTEATQSPAPAPAPASHGPSERWSRMQPCGVDGDIVPKEPEPFGASAAGLEQPGARELPLLGTERDASQTQPRMWEPPLRPAASCRGQAERLQAIQEERARSWSRGTQEQASEQQARAEGALEPGCHKHSVEVARRGSLPSHLQLADPQGSWQEQLAAPEEGETKIALEREKDDMETKLLHLEDVVRALEKHVDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRIAPAALSV
Protein: Carnosine synthase 1 (EC 6.3.2.11) (ATP-grasp domain-containing protein 1) (Q6ZPS2)
Organism: Mus musculus (Mouse)
Function: Catalyzes the synthesis of carnosine and homocarnosine. Carnosine is synthesized more efficiently than homocarnosine.
Interaction partners:
- Carnosine N-methyltransferase
- Beta-Ala-His dipeptidase
- Cytosolic non-specific dipeptidase
- Acidic amino acid decarboxylase GADL1
- Aldehyde dehydrogenase family 3 member B2
- 4-trimethylaminobutyraldehyde dehydrogenase
- Histidine decarboxylase
- Beta-ureidopropionase
- Alpha-aminoadipic semialdehyde dehydrogenase
- Histidine ammonia-lyase
Sequence:
MLLCLSPAWLMKVATPGQEGEAVLLVSKAVSFYPGGLTFLDDFVPPRHATYFLAGLGPESGRGKEAAELARNLTCPTGTSSELSQLLENRLLMRWLLSQQSGVAVPATLAFTYRPPGLLRGGDASPGLRLVELSGKEGQETLVKEEVEAFVHSEALGDASQVAVRLSGCRWRGQQALPLHLRVEPSTVVNTVLGLLEKLEEEESVLVEAMCPPVRLPLPGGPAPGPELAVRICAVVCRIQGDRPLLSKVVCGVGRGDRPVRHHYTLPRTLRVALAQCGLEEEAQVALLEQGIKEAAEGALAAVLALEAGLSVEQRGGRQVHTDFLGVDLVLTVIGRTLTPVVLKLNSGLCLEACGALEGLWAVPRLRRSAEEAAAAPLVETMLRRSGRHLMDGKQLLVIGAGGVSKKFVWEAARDYGLTLHLVESDPNHFASQLVQTFIHFDVTEHRRDEENALLLAELVRARNLKLDGCFSFWDDCLVLTALLCRELGLPCSPPAAMCLAKQKSRTQLHLLRCQGPPWPSTSLHAVACCPLENEADVERAIYQVPLPGVMKLEFGSGAVGVQLVKDGPQCREHFSRILHDLQGEADHPGIGLGWGNAMLLMEFVEGTEHDVDLVVFGGRLLAAFVSDNGPTRLPGFTETAACMPTGLAPEQEAQVVQAAFRCCLGCGLLDGVFNVELKMTGAGPRLIEINPRMGGFYLRDWILELYGVDLLLASTMVACGLQPALPAHPRARGYLVGIMCLVSQHLQLLSSPSSRETLQTLHDQGQLRLNLLEEALIPGQYEEPYCNVACAGPSPAEACHRLLGICQGLGIDRPNYPVAHFLSHFK
Protein: Thyrotropin-releasing hormone receptor (Thyroliberin receptor) (Q9VDC4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Ecdysis triggering hormone
- Cardioactive peptide
- G protein alpha s subunit subunit alpha)
- CNMamide receptor
Sequence:
MLPQIPSYIRTTAMFFCIVIMLLGVVGNVMVPIVIVKTKDMRNSTNIFLTNLSIADLLVLLVCTPTVLVEVNTRPETWVLGHEMCKAVPFVELTVAHASVLTILAISFERYYAICEPLKAGYVCTKGRAILICVLAWGIAALFTSPILWVAEYKLAEYIDGSSVAVCLTQAISDWTLAFFLMTISVFFVVPFVTLVVLYGIIARNLVSNRAAMLRARPTKPELSLKARKQVVLMLGAVVLSFFVCLLPFRVLTLWIILSTDQTLHDLGLVRYYSLLYFCRIMLYLNSAMNPILYNLMSTKFRRGFKRLCQDAGRLLLELVTLGRRKEDSSRGRRGTLSLGMGTNTNTNTNSSNATGATSSSILSRSSNRRCSEDISRTRLKIEMQMPCGSDLEAMAMLQHSTLGKGIARRVSDSRLMPLRNHQPRRHKPQISFDEESLEENKRSEAKIPTKCREKLPGIAREIVNLTENTL
Protein: Anon2D7 (O16054)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MMNLHVAATTTPLPLLMSTSGAMYTAAKAKSSPAVGHRLIDDSSSQQQPSFMSFKLNHDRSLPDTDSTDVDVEDQEADLDGEEHDDHEAEGEEEHDEHDNFEEHARELSNDNDGDIKEHVFPLSDNELHPEVHSIEEVQQQLQQEDADADSAPAPAAAEDNESSQHDAEADGEHEQDGAEGETDLENESPVELIKANEPLAMPSSTESPAAAIEERIKQIAQDFQKMASSQELQPKEELTPQSSLSLNDLIRTLRPNEQQIIPQIDSDYSNAMRVLGKPMAANN
Protein: PPIase cyclophilin-type domain-containing protein (Q57YM9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSGKHLLHREPLGTPHRGIALAHNSNPVVFLEIQFPKSEKVTVAGVQQQSQPVRLLFELFFDLAPTLATNMYGLCIGSCTRLVNHRVQAAGYKDTVLHDAFVGQYVVGGDVMGAAGSGFFSALGERQGPLQVPQNELESLSKMAPERCRQQLGIYLQYWNHTQQPEGGAPSTAKVASTFRIDTVARGAAAKMSDDGVLIGRLVARDAEQRAVAERQLAELARSVYHARRVGSPQEQSQLFPVITLCGEM
Protein: Cytoglobin (Histoglobin) (HGb) (Nitric oxygen dioxygenase CYGB) (NOD) (EC 1.14.12.-) (Nitrite reductase CYGB) (EC 1.7.-.-) (Pseudoperoxidase CYGB) (EC 1.11.1.-) (Stellate cell activation-associated protein) (Superoxide dismutase CYGB) (EC 1.15.1.1) (Q8WWM9)
Organism: Homo sapiens (Human)
Function: May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14660570, ECO:0000269|PubMed:34930834}. Nucleus {ECO:0000269|PubMed:14660570}.
Interaction partners:
- Neuroglobin
- Inactive rhomboid protein 2
- Androglobin
- Erythropoietin
- Alanine aminotransferase 1
Sequence:
MEKVPGEMEIERRERSEELSEAERKAVQAMWARLYANCEDVGVAILVRFFVNFPSAKQYFSQFKHMEDPLEMERSPQLRKHACRVMGALNTVVENLHDPDKVSSVLALVGKAHALKHKVEPVYFKILSGVILEVVAEEFASDFPPETQRAWAKLRGLIYSHVTAAYKEVGWVQQVPNATTPPATLPSSGP
Protein: Heat stress transcription factor A-7b (AtHsfA7b) (AtHsf-10) (Q9M1V5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).
Subcellular location: Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}.
Interaction partners:
- Uncharacterized protein
- Dehydration-responsive element-binding protein 2A
- Pentatricopeptide repeat-containing protein At3g04760
- Probable acyl-activating enzyme 8
Sequence:
MDPSSSSRARSMPPPVPMEGLQEAGPSPFLTKTFEMVGDPNTNHIVSWNRGGISFVVWDPHSFSATILPLYFKHNNFSSFVRQLNTYGFRKIEAERWEFMNEGFLMGQRDLLKSIKRRTSSSSPPSLNYSQSQPEAHDPGVELPQLREERHVLMMEISTLRQEEQRARGYVQAMEQRINGAEKKQRHMMSFLRRAVENPSLLQQIFEQKRDREEAAMIDQAGLIKMEEVEHLSELEALALEMQGYGRQRTDGVERELDDGFWEELLMNNENSDEEEANVKQD
Protein: UBX domain-containing protein 4 (UBX domain-containing protein 2) (Q9Y114)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004406}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004406}.
Interaction partners:
- UBX domain-containing protein 6
- Transitional endoplasmic reticulum ATPase TER94
- Uncharacterized protein
- GH01724p
- GM09977p
- Uncharacterized protein, isoform A
- Small VCP interacting protein, isoform A
- GH28815p
- LD25466p
- AAA+ ATPase domain-containing protein
Sequence:
MNWHKGNIAEAVAASKAKGAVFVVFIEGQDEMTRKLERFVDDSQVRSRLETSDFVAIKVQGNSSAYGQFMSLYKIVPIPSLFFIGKTGTPLEIATGVTASVDELTEKIDKVLILAGKRTEPVAASSSSCAKTLDPNEVRSFAGADGSSSTGESQVVQTASENFRDPETTSVSNSPTGGVEEAKTNPPNSPVAASLASIPAAVSTSSLEGKSGSEAEAASPTALAAEKRAAASKVEGSATTSGAAARNFATNNLIPAVPLMTPAVPVPTQRPLEAQDNTESEERLAEVRNILEQKRKERVEEEKRMEKENELRRRRDGREAQSQQARAKEQELKNMQEQIKRERQEELAARERIRAQIAADRAEQAQRFNTPDISSTTNSVAATAASNVITTDASVSSVDETRLQIRLPGGIQRTKSFPAGEVLATVRVYVRNEMLAASDVRDFTLATSYPRREFQTEDEVKTLNELNLVPNAVVLVLTKEQVNRVVQSGGSLMTMLGTVIWALLTPAAKAFDYINKMGLRPLTQKLSVFMANFRWPGQRAGLEVYQGDAAARRNMDMFSLRPTPAPGYEYDGASTEQTGGSAERPTPQNQPGPGNTPPAHNTSQASASQSQQFQQRPGGYQPPKYGDSNIRRLQDTKKDEKDKDKATYNGNSTQQQ
Protein: Oxytocin receptor (OT-R) (P70536)
Organism: Rattus norvegicus (Rat)
Function: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Oxytocin-neurophysin 1
- Guanine nucleotide-binding protein G
- Voltage-dependent L-type calcium channel subunit alpha-1S
- Voltage-dependent L-type calcium channel subunit alpha-1C
- Guanine nucleotide-binding protein G
- Voltage-dependent calcium channel gamma-4 subunit
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Voltage-dependent calcium channel gamma-3 subunit
Sequence:
MEGTPAANWSVELDLGSGVPPGEEGNRTAGPPQRNEALARVEVAVLCLILFLALSGNACVLLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLGTWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAAEGNDAAGGAGRAALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDVNAPKEASAFIIAMLLASLNSCCNPWIYMLFTGHLFHELVQRFFCCSARYLKGSRPGETSVSKKSNSSTFVLSRRSSSQRSCSQPSSA
Protein: 5-hydroxytryptamine (Serotonin) receptor 2B, isoform E (A0A0B4KFU6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- G protein alpha s subunit subunit alpha)
- Tryptophan 5-hydroxylase 2
Sequence:
MEEDVYASLGAYNDSGGDDWSSSEHLVLWEEDETQRTTANATSRHNQLHVARWNATGNATISATFEDVPFDANNYWALLALVLVLGTAAGNILVCLAIAWERRLQNVTNYFLMSLAITDLMVAVLVMPLGILTLVKGYFPLGSEHCLTWICLDVLFCTASIMHLCTISVDRYLSLRYPMRFGRNKTRRRVTLKIVFVWLLSIAMSLPLSLMYSKNHASVLVNGTCQIPDPVYKLVGSIVCFYIPLGVMLLTYCLTVRLLARQRQNLGGGQQTAAATPGWASGWLGQAPALERRCTWRRLLKPGPGNASSVLHAHSANSTDTDLSTLDNHELWLPDSSIKEPTPTTMTALHQFGAEMLKLSRGLESVASSSTTGSPTKSEFSLSNHLQLQYPSSPQRYAATHQQSHHHNHQQHPAGVYHQQASPKGRHGTTVLGLSTTTLGIERESTRNSLASSRMGGEQSDGTLSQLSQRLRAYKKRRRASSAVPGREKRAGHEDADEDVETPTSTLRRHKRHNSLPKNALYPRHTTVQESLDDDDDEEEESAQQKDQQTKSKICHSDTELDPPQKAKQCHIAGQNHQSDYLQLPSVCTCPYFGDRPLQNCVKSAEVKIISSAFRVTTTTTAVSSSPSEMELLMCSSGNKKSLTSSVSAGITGGPAGAAPATVGSTLSPHSAHNQGSSLTVQSDGSGYLAAPGTPCPGRRKLSISKTASVVTWDSSRHRRRGSSFGGVRTSLLLTPTKTATTSNSSTPLRRSATLRSHQNMNYQGAGECGGKTRTTTSSPCMLQRQQTVRSHHSRNSSVISRNSSRHGRIIRLEQKATKVLGVVFFTFVILWSPFFVLNLLPTVCAECEERISHWVFDVVTWLGYASSMVNPIFYTIFNKVFRQAFKKVLLCRYSSTSAWRPSRXQTPVKPGKLKTNTHKCASVDFQDSTAPVRGVLKRSVAVASDI
Protein: Uncharacterized protein (Q385K5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MTEVFRVQLVSLYRSPEVVGCTAEPVLHTELVIQGQGTTHEGHQENERGIIMGSVGLLAKHHYVAIDVVSHFEEGQPLRIEDSLKSIRARPPPYIHVEGGGRLFLLHPIEHNRYLLSVTVPKTVWRWFGPTALHVLLSTAVRGYEIGTDVAAVASVPTYYPLHNRISENATAVQDALRTRMQQVVEFTAHLTECISQGTVSSPTISQVSAQVVASVNKMCSCSPSALRHSNQFRVMMQKLVWSATNFSEYTSMNGAIASGGLCDGYKRLVVTASAVWHRGEPVFSCGSCEDFQMYLLPAALTTYMCRCLGEGAQQTITIKCFAMHARTGADCLRVPGYLKPMSQPHHVGATVCLSFASAGGWCIALQMEVALNDFTGAPMSHIVSGVIKLISTTLEVPQFTKLMANKSAETLHCAPSASLFTAAASGVMESVRQIGIYQHYCSNGAYAINILQNTCIYHYCKGDTSHPGETAECRNPWPESLDAAALELVQLTSFSLRYGSGRASRNGSALCAAPRSSSPFTILRTNGAVVAMLVVPLLFPDAAVALLVLELAPSGSTAPAIRAFASWLAAKVM
Protein: Bifunctional protein PutA [Includes: Proline dehydrogenase (EC 1.5.5.2) (Proline oxidase); Delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase) (EC 1.2.1.88) (L-glutamate gamma-semialdehyde dehydrogenase)] (Q9I5F6)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Sodium/proline symporter
- Pyrroline-5-carboxylate reductase
- Glutamate dehydrogenase
- NAD-specific glutamate dehydrogenase
- Glutamate 5-kinase
- Gamma-glutamyl phosphate reductase
- Ornithine cyclodeaminase
- Glutaminase-asparaginase
- Glutamate synthase large chain
- Probable glutamine synthetase
Sequence:
MFKASHVLQGEDQTRSAAEFFPVISANYAVDEEAYLGELLQLADPGPDGIEAIRRNARALIETVRSRDNAVDTLDALLRQYSLDTQEGLMLMCLAEALLRVPDAATADALIRDKLSAADWQRHLGQSDNVLVNFAAWGLVMTGKVVNIDERTDGRAPSVISRLVQRSGEPVIRAAMNQAMKLMGKQFVLGRTISEALKNGRPCREQGYTYSFDMLGEAALTAADAEKYMADYRQAIDTVGAEPQVGPGPRPSISIKLSALHPRYEVAQRERVLSELFANVLELAVRARKLNVGITIDAEEADRLELSLELYEKLMRDPAIAGWGEFGLVIQAYSKRCLPVLVWLTLLGRELGARIPLRLVKGAYWDSEIKQCQVQGADGYPVYTRKEGTDTSYLACARYLLSEHTRGVIYPQFASHNAHTVTAILALADEARAAGGEERDFEFQRLHGMGDALYDTVIEKYRRNVRIYAPVGAHKDLLPYLVRRLLENGANSSFVHKLVDPRVPVETLIQHPVTQLRQFKTLANDRIPLPQAIFGAGRKNSQGINMNIQNQWNELELAYKPHLTRQWQAAPIVNGEKLSGPAHEVRCPYDLERLVGSVQYASAEQAGKALDVLQAAWPRWSATPVDERAGILERLADLLEAQRGELMALCTLEAGKSLQDGIDEIREAVDFCRYYAQQARQRLVREELRGPTGERNELFYEGRGIFACVSPWNFPLAIFLGQISAALVAGNTVLAKPAEQTSLIAARTVELMFEAGLPKDVIALLPGDGATLGGVFCRDARVAGVAFTGSTDTARIINRQLAEKPGAIATLIAETGGQNAMIVDSTALPEQVIKDAVQSAFTSAGQRCSALRVMYVQQDIAERVIELLKGAMAELKVGPTEVRVSDVGPVIDAEAKAGLEQHIAALKAAGKLIAETKVPGNLNGHFVAPVAFEISGIDELKKENFGPVLHVVRYAAQDLEKVVQAINATGFGLTMGVHSRNEETARRIEELARVGNLYINRNQIGAVVGVQPFGGHGLSGTGPKAGGPNYLLRFVSERTTSVNTTAVGGNASLLSLADAE
Protein: Telomerase reverse transcriptase (AtTERT) (EC 2.7.7.49) (Q9SPU7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Required to prevent genome instability induced by breakage-fusion-bridge (BFB) cycles. Can extend completely non-telomeric sequences using RNA template in vitro.
Subcellular location: Nucleus {ECO:0000269|PubMed:18212040}. Chromosome, telomere {ECO:0000250}.
Interaction partners:
- Protection of telomeres protein 1b
- H/ACA ribonucleoprotein complex subunit 4
- ATP-dependent DNA helicase 2 subunit KU70
- Protection of telomeres protein 1c
- H/ACA ribonucleoprotein complex subunit 3-like protein
- Protection of telomeres protein 1a
- ATP-dependent DNA helicase 2 subunit KU80
- Putative H/ACA ribonucleoprotein complex subunit 1-like protein 1
- Nonsense-mediated mRNA decay factor SMG7-like
- Nonsense-mediated mRNA decay factor SMG7
Sequence:
MPRKPRHRVPEILWRLFGNRARNLNDAIVDLIPNRNIQPEQCRCRGQGCLGCSSDKPAFLLRSDDPIHYRKLLHRCFVVLHEQTPPLLDFSPTSWWSQREIVERIIEMMQSGCDCQNVICARYDKYDQSSPILELLTSSSWEFLLKRVGHDVMVYLLQQTSIFLPLLGKKHQQVSGPPLCIKHKRTLSVHENKRKRDDNVQPPTKRQWLSSAVDDCPKDDSATITPIVGEDVDQHREKKTTKRSRIYLKRRRKQRKVNFKKVDCNAPCITPSTNGKVSTGNDEMNLHIGINGSLTDFVKQAKQVKRNKNFKFGLSETYSVIPPNHILKTLRPNCSDSKLLMNHIFGEVNVWSTTPSHGKGNCPSGSICLYHSLLKSLKNLIGKTKSSHLKMLLDKHCPVLLLQEDALKSGTTSQSSRRQKADKLPHGSSSSQTGKPKCPSVEERKLYCTNDQVVSFIWAICRYIVPESLLGTTHQMRVLRKNIAWFVSRRRNEKCTVNQFLHKVKPSDFPFFARKELCCMVNGHELQSESIRSTQQMLCTKWISWLFLEIVKKLVHFNFYATESQGGRLNIYYYRKRSWERLISKEISKALDGYVLVDDAEAESSRKKLSKFRFLPKANGVRMVLDFSSSSRSQSLRDTHAVLKDIQLKEPDVLGSSVFDHDDFYRNLCPYLIHLRSQSGELPPLYFVVADVFKAFDSVDQGKLLHVIQSFLKDEYILNRCRLVCCGKRSNWVNKILVSSDKNSNFSRFTSTVPYNALQSIVVDKGENHRVRKKDLMVWIGNMLKNNMLQLDKSFYVQIAGIPQGHRLSSLLCCFYYGHLERTLIYPFLEEASKDVSSKECSREEELIIPTSYKLLRFIDDYLFVSTSRDQASSFYHRLKHGFKDYNCFMNETKFCINFEDKEEHRCSSNRMFVGDNGVPFVRWTGLLINSRTFEVQVDYTRYLSGHISSTFSVAWQNKPVRNLRQKLCYFLVPKCHPILFDSNINSGEIVRLNIYQIFLLAAMKFHCYVYEVSRFWKLHPQTLFKFITISVRYMFRLINRRVRRINTGSSFRPVLKLYKEEVIWLGLDAYIQVLKKKNSRYRMLLIYLKSALSKHSLSQQLSSELRYATDRSNSSSLWKLNY
Protein: Gamma-sarcoglycan (F1Q504)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane, sarcolemma {ECO:0000256|ARBA:ARBA00004274}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004274}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- Alpha-sarcoglycan
- Sarcospan
- Dystroglycan 1
- Dystrophin
- Delta-sarcoglycan)
- Beta-sarcoglycan
- Ribitol-5-phosphate transferase
- Dysferlin
- Syntrophin alpha 1.
- Epsilon-sarcoglycan
Sequence:
MVREQYVTTTEESGVLSPVSEYIYMIGIYGWRKRCLYLFVLLLLIILVVNFALTIWILRVMWFNAEGMGYLQVHEDGLRLEGESDFLFPVYAQEIDSREDSALLIQSSENVTLNARNANGDVTGSVSVGPSQAEGFSKYFNISSNHDENLFYADGSGAIVGKGKLRVTGPEGALFEHSVRTPMVKAVLNKELKLESPTRSLSMDAPKGVHVKALAGNVDVTAHFDILLHSAEGLLILDAETVRLPKLPVGEAGTSGDSQGMYNMYEVCVCPSGKLFFSTAGVSSTCSESQDC