wanglab/gogpt-training-data huggingface dataset:
Protein: Double-stranded RNA-specific editase 1 (EC 3.5.4.37) (RNA-editing deaminase 1) (RNA-editing enzyme 1) (dsRNA adenosine deaminase) (Q91ZS8)
Organism: Mus musculus (Mouse)
Function: Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins; pre-mRNA splicing by altering splice site recognition sequences; RNA stability by changing sequences involved in nuclease recognition; genetic stability in the case of RNA virus genomes by changing sequences during viral RNA replication; and RNA structure-dependent activities such as microRNA production or targeting or protein-RNA interactions. Can edit both viral and cellular RNAs and can edit RNAs at multiple sites (hyper-editing) or at specific sites (site-specific editing). Its cellular RNA substrates include: bladder cancer-associated protein (BLCAP), neurotransmitter receptors for glutamate (GRIA2 and GRIK2) and serotonin (HTR2C), GABA receptor (GABRA3) and potassium voltage-gated channel (KCNA1). Site-specific RNA editing of transcripts encoding these proteins results in amino acid substitutions which consequently alter their functional activities. Edits GRIA2 at both the Q/R and R/G sites efficiently but converts the adenosine in hotspot1 much less efficiently. Can inhibit cell proliferation and migration and can stimulate exocytosis.
Subcellular location: Nucleus {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}. Note=Shuttles between nucleoli and the nucleoplasm. {ECO:0000250}.
Interaction partners:
- Adenosine deaminase
- Glutamate receptor 2
Sequence:
MDIEDEENMSSSSTDIKENRNLDNMPPKDSSTPGPGEGIPLSNGGGGSTSRKRPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYMLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKSEPPFYVGSNGDDSFSSSGDVSLSASPVPASLTQPPLPIPPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALATVFNLHLDQTPSRQPVLSEGLQLHLPQVLADAVSRLVLGKFSDLTDNFSSPHARRKVLSGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYAQLELYLNNKEDQKKSIFQKSERGGFRLKDTVQFHLYISTSPCGDARIFSPHEPVLEGMTPDSHQLTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISNIEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDATIEVINATTGKDELGRPSRLCKHALYCRWMRVHGKVPPHLLRTKITKPTTYHESKLAAREYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSFTP
Protein: Universal stress protein Rv3134c (USP Rv3134c) (P9WFD3)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- DNA-binding transcriptional activator DevR/DosR
- Oxygen sensor histidine kinase response regulator DevS/DosS
- Probable membrane protein Rv1733c
- Uncharacterized protein Rv1738
- Dormancy associated translation inhibitor
- Putative NAD
- Alpha-crystallin
- Putative NAD
- Uncharacterized protein Rv3127
- Uncharacterized protein Rv0080
Sequence:
MSDPRPARAVVVGIDGSRAATHAALWAVDEAVNRDIPLRLVYVIDPSQLSAAGEGGGQSAARAALHDASRKVEATGQPVKIETEVLCGRPLTKLMQESRSAAMLCVGSVGLDHVRGRRGSVAATLAGSALCPVAVIHPSPAEPATTSQVSAVVAEVDNGVVLRHAFEEARLRGVPLRAVAVHAAETPDDVEQGSRLAHVHLSRRLAHWTRLYPEVRVDRAIAGGSACRHLAANAKPGQLFVADSHSAHELCGAYQPGCAVLTVRSANL
Protein: Zinc finger protein 12 (Gonadotropin-inducible ovary transcription repressor 3) (GIOT-3) (Zinc finger protein 325) (Zinc finger protein KOX3) (P17014)
Organism: Homo sapiens (Human)
Function: Transcriptional repressor which suppresses activation protein 1 (AP-1)- and serum response element (SRE)-mediated transcriptional activity.
Subcellular location: Nucleus {ECO:0000269|PubMed:16806083}.
Interaction partners:
- RB-associated KRAB zinc finger protein
Sequence:
MNKSLGPVSFKDVAVDFTQEEWQQLDPEQKITYRDVMLENYSNLVSVGYHIIKPDVISKLEQGEEPWIVEGEFLLQSYPDEVWQTDDLIERIQEEENKPSRQTVFIETLIEERGNVPGKTFDVETNPVPSRKIAYKNSLCDSCEKCLTSVSEYISSDGSYARMKADECSGCGKSLLHIKLEKTHPGDQAYEFNQNGEPYTLNEESLYQKIRILEKPFEYIECQKAFQKDTVFVNHMEEKPYKWNGSEIAFLQMSDLTVHQTSHMEMKPYECSECGKSFCKKSKFIIHQRTHTGEKPYECNQCGKSFCQKGTLTVHQRTHTGEKPYECNECGKNFYQKLHLIQHQRTHSGEKPYECSYCGKSFCQKTHLTQHQRTHSGERPYVCHDCGKTFSQKSALNDHQKIHTGVKLYKCSECGKCFCRKSTLTTHLRTHTGEKPYECNECGKFFSRLSYLTVHYRTHSGEKPYECNECGKTFYLNSALMRHQRVHTGEKPYECNECGKLFSQLSYLTIHHRTHSGVKPYECSECGKTFYQNSALCRHRRIHKGEKPYECYICGKFFSQMSYLTIHHRIHSGEKPYECSECGKTFCQNSALNRHQRTHTGEKAYECYECGKCFSQMSYLTIHHRIHSGEKPFECNECGKAFSRMSYLTVHYRTHSGEKPYECTECGKKFYHKSAFNSHQRIHRRGNMNVIDVGRLL
Protein: Microtubule-associated tumor suppressor 1 homolog (AT2 receptor-binding protein) (Angiotensin-II type 2 receptor-interacting protein) (Coiled-coiled tumor suppressor gene 1 protein) (Mitochondrial tumor suppressor 1 homolog) (Q5HZI1)
Organism: Mus musculus (Mouse)
Function: Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation.
Subcellular location: Mitochondrion {ECO:0000250}. Golgi apparatus. Cell membrane. Nucleus. Note=In neurons, translocates into the nucleus after treatment with angiotensin-II.
Interaction partners:
Sequence:
MNDDNSDRTEDGSRYVFIRDKNSNPSEYYQTSLSAQCPSVSHGDWNSDNPDAMVVDYEMDPAVDSSESVSLSHQCVEELAYPEPSSDFMGKHEFTMYSELTCQSPALVNTGKPQDLHSNCDSLEAIQDEKFDPLKPCECRSDDDYACGDSPEVLELKQTYGMKVDTANYTFIARHDIEQGQPLHAPGGLQTTVRDRNALSSCGRTPPHSSKMYVRGVNYNRENFENLQATPSKTLNTTFTVISDVLMQTDSPDVGVQGQNSLGNVTKEYTDGTRRGLIGEKEIQAVTLVSDGMEVPNGSASQEFYCVSEDDPNSETHSHGPYAQQEMGQNLRGTLPNCHVDGECPVLVPAFEKSKTRVLGSECKVTVTEDPHIDSHDNDSDIQSSTEELTLRSVSGQRGSPYEMGWGENGGAICTDKAGCMSTPVEQPPNLSFRLEPAEVKKYNNVENGPRDAKRAPNLKGEPTNMPKPNLGKSATKTNTTVGSKVRKTEIISYPTPNFKNIKAKVISRSVLQPKDTSIMKDTPSPQVTGGSSPSPGPSKHLTMMNKAPRSDFKASKKAEIPINKTHKQQFNKLITSQAAQVTTHSKNASLGVPRTTSATKSNQENVDKTGSPHAGSETGSVAAFFQKIKGILPVKMKSSECLEVTYVSHIDQISPEKGEQDGEAPMEKQELGKQATNEIFESKSLLVGSAPKTSTTPGRSSSKPDSRSLRKTPGLKAKVGPTAACLRRKSESRTLGSDRALSPQRIRRVSGSGGHAAINKYEEKPPKQAFQNGSGPLYLKPLVPRAHSHLLKTSPKGPSRKSLFTAFNSVEKGRQKNPRSLCIQTQTAPDVLSSERTLELAQYKTKCESQSGFILHLRQLLSRGNTKFEALTVVIQHLLSEREEALKQHKTLSQELVSLRGELVAASSACEKLEKARADLQTAYQEFVQKLNQQHQTDRTELENRLKDLYTAECEKLQSIYIEEAEKYKTQLQEQFDNLNAAHETTKLEIEASHSEKVELLKKTYETSLSEIKKSHEMEKKSLEDLLNEKQESLEKQINDLKSENDALNERLKSEEQKQLSREKANSKNPQVMYLEQELESLKAVLEIKNEKLHQQDMKLMKMEKLVDNNTALVDKLKRFQQENEELKARMDKHMAISRQLSTEQAALQESLEKESKVNKRLSMENEELLWKLHNGDLCSPKRSPTSSAIPFQSPRNSGSFSSPSISPR
Protein: Serine/threonine-protein kinase nekl-2 (EC 2.7.11.1) (Never in mitosis A kinase-like 2) (NimA-kinase-like 2) (O01775)
Organism: Caenorhabditis elegans
Function: Probable serine/threonine-protein kinase required for the completion of molting. May play a role in endocytosis in the hypodermis syncytium.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:25523392}. Note=In hyp7 syncytium, localizes in puncta and small tubules near the plasma membrane apical region. Does not co-localize with nekl-3. {ECO:0000269|PubMed:25523392}.
Interaction partners:
- SAM domain-containing protein
- ANK_REP_REGION domain-containing protein
- ANK_REP_REGION domain-containing protein
- JmjC domain-containing protein
- Probable [pyruvate dehydrogenase
Sequence:
MDNYEKVRVVGRGAFGVCWLCRGKNDASHQKVIIKLINTHGMTEKEENSIQSEVNLLKKVQHPLIIGYIDSFIMDNQLGIVMQYAEGGTLERLINDQRAIKDSNMREYFPEKTVLDYFTQILIALNHMHQKNIVHRDLKPQNILMNRRKTVLKLSDFGISKELGTKSAASTVIGTPNYLSPEICESRPYNQKSDMWSLGCVLYELLQLERAFDGENLPAIVMKITRSKQNPLGDHVSNDVKMLVENLLKTHTDKRPDVSQLLSDPLVLPYLISIHCDLGRIEPPPTDKRKPSASLSSRLRTYPTQSTLRPYSLSSNAPTTHLTQLTPMPSHIDSGFFSSGRTSNQRTQSRSQVHSKY
Protein: CAAX prenyl protease (EC 3.4.24.84) (Q7JV41)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|RuleBase:RU366005}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU366005}.
Interaction partners:
- CAAX prenyl protease 2
- AT13932p
- LD06095p
Sequence:
MAFYDTWPKVDPIIVLVVLCLIVLVDRIWEMILTKRQQLVCLNAIMVPEELRGIIPPEIYHRARIYELHKTELQIWKYLIDLIITLCELILGFYPFLWSLSAKTLQKITSQEIWITLIFVFYLTIYICIRFLPVLIYDKCLLELRYGMSGKFPWYLYCCIGAMSILLSQLVLFPLAAAIVFSVKFIGYYFFLWFWLFWATFTLLLVFFLPYCCIPCIGRQVVLPEGTALYMEVKRVCDVVGFPMKRVFIIKTRTMQYSNAYFYGSCCLKRIVIFDTLLLNKGKEPNEIHPYEVGRGLTNIQVAGVVCHELGHWKHGHFYKATIIMKIHFFITMGLFGLFFHSPQLYMAVGFEPGVMPIIVGFIIVLKFALTPYLTLANVLMLWNLRRFEYAADKFAHRMGYSIQLRMALVKIYADHMSFPVYDQCYARWHHTHPTILQRLAYQQKLDVKAMNAGTY
Protein: PadR family transcriptional regulator (A7MXA8)
Organism: Vibrio campbellii (strain ATCC BAA-1116)
Interaction partners:
Sequence:
MKNANESVDSLFTSLLTIWIEDMSLPHVILTVLSTRDATGYDITKEFSASIGYFWKASHQQVYRELNKMAEKELVTCVLEPQEGKPDRKVYSITDAGRSALGEWFDQPTAHPTVRDEFSAKLMACAVQPAAPFRDQLSELVEESRKLVAHYKEIEAAYYATPSTLDKQARLERLTLRRNLMLREAWINWAEEVLTELEVIG
Protein: Kinesin-like protein (A0A0G2JUD6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MINKSEKPESCDNVKVVVRCRPLNEREKSMCYRQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAVPGLRGVIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGVDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEVSGSDISGSEEDDNEEGELGEDGEKRKKRRDQAGKKKVSPDKMMEMQAKIDEERKALETKLDMEEEERNKARAELERREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRKELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIPQDYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKERDPFEVDLSHVYLAYTEESLRQSLMKLERPRTSKGKARPKTGRRKRSAKPETVIDSLLQ
Protein: Uncharacterized membrane protein C6F6.13c (O14244)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MPISSPGTRCSSDLKDPTLQQYSAESVSTEQSLGTFEESKGSITENYVQDSSVDEHDDGNWQPMEVISLEPTHLINDIDDDNEIIEEKKETEKVEESELEPRYTRVFRDEDDDQKHQLDSEAIKLLDIADHGNEEISMDSQLEITGNILSETEKMAYAGVCRLLILKMVDKIACFTTLPWYRGECKAALEDTIMWADKTTSCIYEHLGVTVEEQKMIENLHKHSVQIDDLSKILVSAHRAQTVSSLDAVLVDEVESSDSLSSLGKEKPVQIDVRWTVLCDLFLVLISKSLYDCRSRSLLMAVGEVLDINEFDVAKFEKHIVETIQIDDTGELEAGSSANTEAVMKLRRKVSRRKKYILMGLAGIGGGLVIGLSSGLLAPIISAGIGAAFTTVGLSGVATSGFLAGGGSAALITAGGAISGAHIGTTGMAHRKADVKTFEFRPLHAQRRANVIVTVSGWMLSKEDDVRLSFATLDPIVGDIYSVFWEPEMLASAGQTMNILATEVVTQSLQQVLGSTVLVSLMGALQWPLILTKLGYLIDNPWNNSLDRAKATGQLLADMLCYRSLGVRPVTLVGYSLGARVIYYCLRELEKKKEFSIIENVYLFGTPVIFKRTSWLKAASVVSGRFVNGYKKNDWILGYLFRATSGGIGRVAGLRQIDCIPGIENIDVTNLVSGHLAYRESMPILLAAVGFEVLDEEVDLVSEPIPEPLRERQSQLLYEIEAEECQNKQKELIEKSLMQKGRSLSPKKSNAFFDSKKIREELKKVKKKYGSSFNSRWY
Protein: Sterol 4-C-methyltransferase strm-1 (STRM-1) (EC 2.1.1.-) (Sterol A-ring methylase-1) (Q9TYP1)
Organism: Caenorhabditis elegans
Function: Catalyzes the methyl transfer from S-adenosyl-methionine to the C-4 of the A-ring sterols such as lathosterone (5alpha-cholest-7-en-3-one) thereby rendering them unsuitable as ligand precursors. May irreversibly shunt sterols away from hormone dafachronic acid production. Dafachronic acids act as ligands and bind directly to the nuclear hormone receptor (NHR) daf-12 suppressing dauer formation and inducing reproductive growth. By reducing the biosynthesis of dafachronic acids, this methyltransferase can regulate dauer larva formation.
Interaction partners:
- Sigma non-opioid intracellular receptor 1
- 7-dehydrocholesterol reductase
- 3beta-hydroxysteroid dehydrogenase/Delta
- 3beta-hydroxysteroid dehydrogenase dhs-16
- NADPH--cytochrome P450 reductase
- Winged helix-turn-helix domain-containing protein
- Fatty acid hydroxylase domain-containing protein
- 3-ketosteroid oxygenase
- Fatty acid hydroxylase domain-containing protein
- Cholesterol 7-desaturase
Sequence:
MSINMNANFLKLLTHFRRHDLTNFKSEHDTLYEKALETGDHLEVTSHYYSVMSTVIDEYFGGNFHFVPPKFEGQKLEEALKSLHCHIAEKLELSENVHCLDIGCGIGGVMLDIADFGAKLTGVTIAPNEAEIGNEKFANMGISDRCKIVAADCQKMPFEDSTFDVAYAIYSLKYIPNLDKVMKEIQRVLKPGGKFIVYDLIKTNDYDKDNKEHYKTLHHLEYACGMPSLHTQSEVEAAAEKWEMPVVERENLEETYGNRAFHYCFSASPMFMWLVSSPVIDHTIRMAEILRILPAGFKQFNRTFLCGTVNSIVGGGRMGILSGADILLFEKKKI
Protein: ER-derived vesicles protein 41 (O94283)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi. Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}. Golgi apparatus membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}. Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}. Note=Recycles between endoplasmic reticulum and Golgi. Resides in the endoplasmic and Golgi compartments, and then packaged into endoplasmic reticulum derived vesicles (By similarity). {ECO:0000250}.
Interaction partners:
- Uncharacterized protein C24B11.08c
- Uncharacterized derlin-like protein C1687.17c
- tRNA modification GTPase mss1
- Putative ERAD-associated E3 ubiquitin-protein ligase component
- Uncharacterized Sel1-like repeat-containing protein C1B3.10c
Sequence:
MLRSRVPANIRAFDAFPKFSKEYRRQSSSRGGFFTILLSVLIVVLVFSQCVQYIRGIREQELFIYDSVSELMDLNIDITIAMPCSNLRIDVVDRTKDLVLATEALTLEEAFIKDMPTSSTIYKNDRYAGLRWARTEKFRKKNNAEPGSGTACRIYGQLVVNRVNGQLHITAPGWGYGRSNIPFHSLNFTHYIEELSFGEYYPALVNALDGHYGHANDHPFAFQYYLSVLPTSYKSSFRSFETNQYSLTENSVVRQLGFGSLPPGIFIDYDLEPLAVRVVDKHPNVASTLLRILAISGGLITVASWIERVYSSRAHRSTSEADMLGLLGKSETE
Protein: AT-hook motif nuclear-localized protein 25 (AT-hook protein of GA feedback 1) (Q6DBQ1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs) (By similarity). Binds the DNA sequence GNFEI (GA-negative feedback element I) in the GA3OX1 promoter. Binding to GNFEI sequence is required for GA-negative feedback regulation of GA3OX1.
Subcellular location: Nucleus {ECO:0000269|PubMed:17277098}.
Interaction partners:
Sequence:
MSSYMHPLLGQELHLQRPEDSRTPPDQNNMELNRSEADEAKAETTPTGGATSSATASGSSSGRRPRGRPAGSKNKPKPPTIITRDSPNVLRSHVLEVTSGSDISEAVSTYATRRGCGVCIISGTGAVTNVTIRQPAAPAGGGVITLHGRFDILSLTGTALPPPAPPGAGGLTVYLAGGQGQVVGGNVAGSLIASGPVVLMAASFANAVYDRLPIEEEETPPPRTTGVQQQQPEASQSSEVTGSGAQACESNLQGGNGGGGVAFYNLGMNMNNFQFSGGDIYGMSGGSGGGGGGATRPAF
Protein: Dynein cytoplasmic 1 intermediate chain 1 (F1SF88)
Organism: Sus scrofa (Pig)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSIGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTSGGEESSSLMFDSNHPVSCFRLESDAVHCKRGVSFSGGGDHTVLLHTCQSYLNEDEEDEEMVEPKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEGRIWIYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELTA
Protein: NAD/NADP-dependent indole-3-acetaldehyde reductase (EC 1.1.1.190) (EC 1.1.1.191) (AKR3C2) (O13848)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Uncharacterized oxidoreductase C215.11c
- Zinc-type alcohol dehydrogenase-like protein C16A3.02c
- Zinc-type alcohol dehydrogenase-like protein C2E1P3.01
- Uncharacterized protein C27E2.11c
- C-1-tetrahydrofolate synthase, cytoplasmic
- Large ribosomal subunit protein uL10
Sequence:
MLIAAMGPKIPVPAYGVGTALFKKEKGEINRTIVDSVKNALAAGFIHIDCAEVYGNEEEVGVALKEANVPRSKLFITSKVMHNVDNIPEALNESLRKLGTDYLDLYLLHSPIPFYEKKIPISEGWKAMETALGTGLVHSVGVSNFRIPDLEELLKTSTITPRVNQIEFHPQVYKAAKPLVEFCQSKGIIVEGYGPLSPLVRDAQGPVAEFTKSLESKYHVSDTQILLKWAYSKGVIPITTTSKIERMKECLNFDSFTLDKADIDELGTLGVQHHKRTFMKHMDE
Protein: Clc-like protein (Q21731)
Organism: Caenorhabditis elegans
Interaction partners:
- LRRCT domain-containing protein
- Menorin
- Neuroglian
- Leukocyte cell-derived chemotaxin-2 homolog
- DH domain-containing protein
- Actin-4
- Furin-like protease kpc-1
Sequence:
MPLIMYKFLLVTSIFLIVSGLILTAFSLFSPLWEVVDFPRSHLSHHHGLWWDCIVHHETLIPLHEDQAELRGDRCDSKMDSSVQASLRVALEKGDEEARELLLHRFLPHHKGVIFFAVFTFVFGLISILIGSCSPCFPPNALLYVVGVFMTGACSLLADIIYIFAFNQKPIFTKEQSEPHQEVLSRRERGSIGPIYKRLGIATYMHMFGSMLLIAAFIFSIFCAYFLITSKHAHDVCCTSRKEYREQTKWKNNGLILKTGRVNHQSHRPFVVIDDDSSM
Protein: Mimecan (Osteoglycin) (D3ZVB7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Interaction partners:
- Osteomodulin
- Lumican
- Fibromodulin
- Prolargin
- Keratocan
- Adhesion G protein-coupled receptor L1
- Adhesion G protein-coupled receptor L3
- Adhesion G protein-coupled receptor L2
Sequence:
MKTVHPTLLLLLFVPLTQQTPQTQLDSHVNSKYGTDNSEETKFIQDYEDKYLDGKNIKEKETMIIPDEKSLQLQKDEVIPSVPTKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADMPNLRRLDFTGNLIEDIEDGTFSKLSLLEELTLAENQLLRLPVLPPKLTLLNAKYNKIKSKGIKANTFKKLNKLSFLYLDHNDLESVPPNLPESLRVIHLQFNSISSITDDTFCKANDTRYIRERMEEIRLEGNPIALGKHPNSFICLKRLPTGSYF
Protein: GDSL esterase/lipase At1g09390 (EC 3.1.1.-) (Extracellular lipase At1g09390) (O80522)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- GDSL esterase/lipase At5g62930
- At1g62510
- Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein
- CHY-type/CTCHY-type/RING-type Zinc finger protein
- At2g10940/F15K19.1
- Non-specific lipid transfer protein GPI-anchored 31
- Protein PHLOEM PROTEIN 2-LIKE A9
- At2g45180
- Protein PHLOEM PROTEIN 2-LIKE A1
- Non-specific lipid-transfer protein 10
Sequence:
MATLSLHSHSFLLVLLPFILILRQNLAVAGGCQVPPVIFNFGDSNSDTGGLVAGLGYSIGLPNGRSFFQRSTGRLSDGRLVIDFLCQSLNTSLLNPYLDSLVGSKFQNGANFAIVGSSTLPRYVPFALNIQLMQFLHFKSRALELASISDPLKEMMIGESGFRNALYMIDIGQNDIADSFSKGLSYSRVVKLIPNVISEIKSAIKILYDEGGRKFWVHNTGPLGCLPQKLSMVHSKGFDKHGCLATYNAAAKLFNEGLDHMCRDLRTELKEANIVYVDIYAIKYDLIANSNNYGFEKPLMACCGYGGPPYNYNVNITCGNGGSKSCDEGSRFISWDGIHYTETANAIVAMKVLSMQHSTPPTPFHFFCGG
Protein: Fibronectin type-III domain-containing protein (Q3UVK9)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MRPLPLWLPSLLLCGLGAAASSPDSFSQLAAPLNPRLHLYNDEQILTWEPSPSSNDPRPVVYQVEYSFIDGSWHRLLEPNCTDITETKCDLTGGGRLKLFPHPFTVFLRVRAKRGNLTSKWVGLEPFQHYENVTVGPPKNISVTPGKGSLVIHFSPPFDVFHGATFQYLVHYWEKSETQQEQVEGPFKSNSIVLGNLKPYRVYCLQTEAQLILKNKKIRSHGLLSNVSCHETTANASARLQQVILIPLGIFALLLGLTGACFTLFLKYQIRVKYWFQAPPNIPEQIEEYLKDPDQFILEVLDKDGSPKEDSWDSVSIISSPEKERDDVLQTP
Protein: Tumor necrosis factor receptor superfamily member 4 (MRC OX40) (OX40 antigen) (OX40L receptor) (CD antigen CD134) (P15725)
Organism: Rattus norvegicus (Rat)
Function: Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity (By similarity).
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- Tumor necrosis factor ligand superfamily member 4
- CD70 antigen
- T-lymphocyte activation antigen CD80
- T-lymphocyte activation antigen CD86
- ICOS ligand
- TNF receptor superfamily member 9
- CD40 ligand
- Inducible T-cell costimulator
- CD27 antigen
- TNF superfamily member 9
Sequence:
MYVWVQQPTAFLLLGLSLGVTVKLNCVKDTYPSGHKCCRECQPGHGMVSRCDHTRDTVCHPCEPGFYNEAVNYDTCKQCTQCNHRSGSELKQNCTPTEDTVCQCRPGTQPRQDSSHKLGVDCVPCPPGHFSPGSNQACKPWTNCTLSGKQIRHPASNSLDTVCEDRSLLATLLWETQRTTFRPTTVPSTTVWPRTSQLPSTPTLVAPEGPAFAVILGLGLGLLAPLTVLLALYLLRKAWRSPNTPKPCWGNSFRTPIQEEQTDTHFTLAKI
Protein: Microfibrillar-associated protein 1 (Spliceosome B complex protein MFAP1) (P55081)
Organism: Homo sapiens (Human)
Function: Involved in pre-mRNA splicing as a component of the spliceosome.
Subcellular location: Nucleus {ECO:0000269|PubMed:28781166}.
Interaction partners:
- Splicing factor 3B subunit 1
- Splicing factor 3A subunit 3
- 116 kDa U5 small nuclear ribonucleoprotein component
- Small nuclear ribonucleoprotein Sm D1
- Small nuclear ribonucleoprotein Sm D2
- Splicing factor 3B subunit 4
- Small nuclear ribonucleoprotein G
- Pre-mRNA-processing-splicing factor 8
- U2 small nuclear ribonucleoprotein A'
- Splicing factor 3A subunit 1
Sequence:
MSVPSALMKQPPIQSTAGAVPVRNEKGEISMEKVKVKRYVSGKRPDYAPMESSDEEDEEFQFIKKAKEQEAEPEEQEEDSSSDPRLRRLQNRISEDVEERLARHRKIVEPEVVGESDSEVEGDAWRMEREDSSEEEEEEIDDEEIERRRGMMRQRAQERKNEEMEVMEVEDEGRSGEESESESEYEEYTDSEDEMEPRLKPVFIRKKDRVTVQEREAEALKQKELEQEAKRMAEERRKYTLKIVEEETKKELEENKRSLAALDALNTDDENDEEEYEAWKVRELKRIKRDREDREALEKEKAEIERMRNLTEEERRAELRANGKVITNKAVKGKYKFLQKYYHRGAFFMDEDEEVYKRDFSAPTLEDHFNKTILPKVMQVKNFGRSGRTKYTHLVDQDTTSFDSAWGQESAQNTKFFKQKAAGVRDVFERPSAKKRKTT
Protein: Cytochrome (Q5A6K0)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Dit1p
- Uncharacterized protein
- Cytochrome b5 heme-binding domain-containing protein
Sequence:
MFKNEDVFAKSGNHVKIPNSVLATYTGDNIISAHGELWKLYRDVVAQSIQFPDLKPISKNTQKLLRFLDNEMGSANQATISVTDILQKYSLANVCESVLGVNFNVLDDKQSLMHEKIKYVKSQIFNPIFLNFPYFDNFPIPSRLKARREVIGFRKWYGQSLIEKYNLQLPNSAATKLVDSLIKEKLTEKQFLDNAIILMIAGHENPLLLMLSLLYVVSKYPQVQELIRNETETTKPYLHSVIYETLRMYPPLGLIINRCTTRITKLGNIVIPKNVYCGYNNFGTGRDRNVWGSDADIFKPERWGLEIDEINKKFTLAKRSAELPAFHGRKRACLGEKYALFEVKQFLLAILGEYKVSLDPNWKEQLTPAGPISPLRLKLNFEKLTVS
Protein: Two-component response regulator ARR16 (Q9SHC2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Type-A response regulators seem to act as negative regulators of the cytokinin signaling.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Putative two-component response regulator ARR19
- Two-component response regulator ARR18
- Putative two-component response regulator-like APRR6
- Putative two-component response regulator-like APRR4
- Two-component response regulator ARR14
- Auxin-responsive GH3 family protein
- Auxin-responsive GH3 family protein
- Auxin-responsive GH3 family protein
- Auxin-responsive GH3 family protein
- Auxin-responsive GH3 family protein
Sequence:
MNSSGGSCSSLMDVVAYDHHLHHGHDEELHVLAVDDNLIDRKLVERLLKISCCKVTTAENALRALEYLGLGDQNQHIDALTCNVMKVSLIITDYCMPGMTGFELLKKVKESSNLREVPVVIMSSENIPTRINKCLASGAQMFMQKPLKLADVEKLKCHLMNCRS
Protein: Nuclear pore complex protein Nup88 (88 kDa nucleoporin) (Nucleoporin Nup84) (Nucleoporin Nup88) (O08658)
Organism: Rattus norvegicus (Rat)
Function: Component of nuclear pore complex.
Subcellular location: Nucleus, nuclear pore complex {ECO:0000250|UniProtKB:Q99567}.
Interaction partners:
- Nuclear pore complex protein Nup214
- Nuclear pore complex protein Nup214
- E3 SUMO-protein ligase RanBP2
- Nuclear pore complex protein Nup98-Nup96
- Nuclear pore complex protein Nup155
- Nuclear pore complex protein Nup93
- Nucleoporin NUP35
- Nucleoporin 205
- Nuclear pore complex protein Nup107
- Nuclear pore complex protein Nup85
Sequence:
MAAAAGPVGDGELWQSWLPNHVVFLRLREGLKNQSPAEADKPATSTSPSCPPLPPHLPTRNLVFGLGGELFLWDAEGSAFLVVRLRGPSGGSVEPPLSQYQRLLCINPPLFEIHQVLLSPTQHHVALIGTKGLMALELPQRWGKDSEFEGGKATVNCSTIPIAERFFTSSTSLTLKHAAWYPSEMLDPHIVLLTSDNVIRIYSLREPQTPTKVIVLSEAEEESLILNKGRAYTASLGETAVAFDFGPLVTVSKNMFEQKDREAVAYPLYILYENGETFLTYVSLLHSPGNIGKLLGPLPMHPAAEDNYGYDACAILCLPCVPNILVIATESGMLYHCVVLEGEEDDDQTLEKSWDPRADLIPSLYVFECVELELALKLASAEDDPFASDFSCPIKLHRDPKCPSRYHCSHEAGVHSVGLTWIHKLHKFLGSDEEDKDSLQELTAEQKCFVEHILCTKPLPCRQPAPIRGFWIVPDILGPTMICITSTYECLIRPLLSTVHPASPPLLCTREDAGVAESPLRILAEAPDSFEKHIKRILQRSAANPALLKSSEKDLAPPPEECLQLISRATQVFREQYILKQDLAKEEIQRRVKLLCDQKRKQLEDLNYCREERKSLREMAERLADKYEEAKEKQEDIMNRMKKVLHSFHTQLPVLSDSERDMKKELQLIPDQLRHLGNAIKQVTMKKDYQQRKMEKVLSPQKPTITLSAYQRKCIQSILKEEGEHIREMVKQINDIRNHVNF
Protein: Growth hormone receptor (Q0R5T3)
Organism: Bos taurus (Bovine)
Interaction partners:
Sequence:
EGKLEEVNTILAIHDNYKHEFYNDDSWVEFIELDIDDPDEKTEGSDTDRLLSNDHEKSLNIFGAKDDDSGRTSCYEPDILEADFHVSDMCDGTSEVAQPQRLKGEADISCLDQKNQNNSPSNDAAPASQQPSVILVEENKPRPLLIGGTESTHQAVHTQLSNPSSLANIDFYAQVSDITPAGNVVLSPGQKNKTGNPQCDTHPEVVTPCQANFIVDNAYFCEVDAKKYIALAPHVEAESHVEPGFNQEDIYITTESLTTTAGRSGTAEHVPSSEIPVPDYTSIHIVQSPQGLVLNATALP