wanglab/gogpt-training-data huggingface dataset:
Protein: Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive (EC 2.5.1.54) (3-deoxy-D-arabino-heptulosonate 7-phosphate synthase) (DAHP synthase) (Phospho-2-keto-3-deoxyheptonate aldolase) (P00887)
Organism: Escherichia coli (strain K12)
Function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).
Interaction partners:
- 3-dehydroquinate synthase
- Bifunctional chorismate mutase/prephenate dehydratase
- Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive
- Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive
- Shikimate kinase 2
- T-protein
- Trp operon repressor
- Phosphoenolpyruvate synthase
- 3-phosphoshikimate 1-carboxyvinyltransferase
- Anthranilate synthase component 1
Sequence:
MNRTDELRTARIESLVTPAELALRYPVTPGVATHVTDSRRRIEKILNGEDKRLLVIIGPCSIHDLTAAMEYATRLQSLRNQYQSRLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNHGLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGAIGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHIIMRGGKKPNYHADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRRQLEVCEDICQQIRNGSTAIAGIMAESFLREGTQKIVGSQPLTYGQSITDPCLGWEDTERLVEKLASAVDTRF
Protein: Lymphocyte enhancer binding factor 1 (Lymphoid enhancer-binding factor 1) (Q9W7C0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Catenin beta-1
- Catenin, beta 2.
- Transducin-like enhancer protein 3-A
- Mitogen-activated protein kinase
- Mitogen-activated protein kinase
- Mothers against decapentaplegic homolog.
- Axin-2
- C-terminal-binding protein 1
- C-terminal-binding protein 1
- Mothers against decapentaplegic homolog.
Sequence:
MPQLSGGGGGGDPELCATDEMIPFKDEGDPHKEQIFAEISHSEEEGDLAEIKSSLVNETEISPNSNSHDAARQSQITPDSYHEKHRDHPDDGKLQDLYSKGHPYPSYPGYIMMTNMNNEPYMNNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFAPGPHSGHHPQDVNPKQAGMPRHHPGPDIPNFYPLSPGGVGQMTPPLGWFSHHMVPGPPGPHATGIPHPAIVNPQVKQEHDTDLMHMKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKIQEPASGTGQRMKTAYI
Protein: DDB1- and CUL4-associated factor homolog 1 (Protein DDB1-CUL4 ASSOCIATED FACTOR 1) (Protein DCAF1) (Q9M086)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the CUL4-RBX1-DDB1-DCAF1 E3 ubiquitin-protein ligase complex, DCAF1 may function as the substrate recognition module within this complex. Appears to be required for plant embryogenesis and to affect several other developmental processes including leaf, shoot, and flower development.
Subcellular location: Nucleus {ECO:0000269|PubMed:18552200}.
Interaction partners:
- Cullin-4
- DNA damage-binding protein 1a
- DNA damage-binding protein 1b
- DET1- and DDB1-associated protein 1
- Cullin-like protein 5
- Putative cullin-like protein 4
- AT5g40270/MSN9_170
- HD domain-containing metal-dependent phosphohydrolase family protein
- RING-box protein 1a
- THO complex subunit 6
Sequence:
MDGQEHAEVPNSMVEDDQSVVAAEAIAELANSTGEPNPEEGEEQSVEDELIAKAQKLMEDITSVANNPNPNILHALSQLLESQESLFLEENGHFSNARGSHNSGKLCILIRENDEFFELISSTFLSENSYSTAVKAASARLLMNCSLTWMYPHVFDDAVTENFKNWVMEEAVKFPGEDSAKKEASDFEMLKTYSTGLLALSLASRGQIVEDVLTSGLSAKLMHYLRVRVLKEPSTSRIHTTETKHVSLKTKEEGRSRVRKIVDTVEGDHVLETDSGREMGQTDVQPDGEFEIDGRDVFNVSGVVDCKIKPGDDNSVRDDPSRHRLNRSKSRGRGRVHEGAPDTEVLLASPRLGRLLVRDRDLSKISDGRNAEDVTVCLGKMKSGIMEIEREDNDECFQGCIIGTKNITDLVKRAVGAAETEARAAHAPDDAAKAAGDAAAELVKTAALEEFKSSGSEEAAVSAATRAAITVIDAAEVSRNPTCVTSDQTTDVSEVSLPDIESLAQLQEKYCIQCLEILGEYVEVLGPVLHEKGVDVCIVLLERTSQLDDRSTVSPLLPDVMKLICALAAHRKFAAMFVERRGILKLLAVPRVSETFYGLSSCLYTIGSLQGIMERVCALPLVVIHQVVKLAIELLDCSQDQARKNSALFFAAAFVFRAILDAFDAQDSLQKLLAILKDAASVRTGANTDRSAPEVMTSSEKQMAFHTCFALRQYFRAHLLLLVDSIRPSRISRGGVPSSMKPNIRAAYKPLDISNEAVDAIFLQLQKDRRLGPTFVKAQWPAVNNFLASSGHVTMLELCQTPPVDRYLHDLLQYAFGVLHIVTSIPDGRKAIAHATLSNNRAGIAVILDAANISNSIVDPEIIQPALNVLINLVCPPPSLSNKPPLAQNHQPVPGQATTRPSTDVAVGTQSTGNAPQTPVAPASSGLVGDRRIFLGAGTGSAGLAAKLEQVYRQAREAVRGNDGIKILLKLLQPRIYVNPPATPDCLRALACRVLLGLARDDTIAQILTKLEVGKSLSELIRDSGGQSSGTDQGRWQAELAQVALELIGIVTNSGHATTLTASDAATPTLRRIERAAIAAATPITYDSKELLLLIHEHLQASGLGDTASALLKEAQLTPLPSSASPSSIAYSTTQEMSTPLAQEQWPSGRANSGFFTSKPKVCAHDEDPNSRSNAALSAKKKHLASSTLEMPTPVAQQQWPSGRANCGFCPSIPKINARDEDPSSRGNAAPSAKKKQLTFSPSFSSQSRKQSFSHDALPQSTQRINCCSNSDPALADTSETAAELVLKNDLDADAQFKTPISFPRKRKLSELRDSSVPGKRIDLGERRNSTFADGSGLQTPASALDANQSGSSRLGQMTPASQLRLPSDPQPSNPERLSLDSLVVQYLKHQHRQCLAPITTLPPVSLLHPHVCPEPKRLLEAPLNMTGRLGTRELQSFYSGVHGNRRDRQFVFSRFKSWRSFRDETALFTCIALLGGTNHIAVGSHAGEIKIFEASSGSMLESVSGHQAPVTLVQPYVSRDTQLLLSSSSSDVQLWDASSITGGPRHSFDGCKAAKFSNSGLQFAALSCEASRKDVLLYDVQTCSPCQKLTDTVTSSRSNPYSLVHFSPCDTLILWNGVLWDRRIPEKVRRFDQFTDYGGGGFHPSRNEVIINSEIWDMRTFKLLRSVPSLDQTAITFNSRGDVIYAMLRRNIEDVMSAVHTRRVKHPLFAAFRTLDAINYSDIATIPVDRCLLDFATEPTDSFLGLITMEDQEDMFSSARMYEIGRRRPTDDDSDPDDDDETEDEDEDDEEEDDLDRILGLAGDNSDSGDDDLSSEDNEDSVSDFDEEADILIDGDFMEELIEGENEDDGNGEDEDDDDDGEMQDFMSSGEEDDYRDNIRSS
Protein: RHOMBOID-like protein 12, mitochondrial (AtRBL12) (EC 3.4.21.-) (Presenilins-associated rhomboid-like protein) (Q9FZ81)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable rhomboid-type serine protease that catalyzes intramembrane proteolysis. Unable to cleave either of the yeast Pcp1 substrates in yeast cells.
Subcellular location: Mitochondrion membrane {ECO:0000269|PubMed:18543065, ECO:0000269|PubMed:22738221}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Large ribosomal subunit protein uL18y
- At1g43860
- Translation elongation factor EF1B/ribosomal protein S6 family protein
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Large ribosomal subunit protein eL42z/eL42y
- Large ribosomal subunit protein uL5c
- Large ribosomal subunit protein bL28c
- Large ribosomal subunit protein uL24c
- Large ribosomal subunit protein eL38z/eL38y
- Small ribosomal subunit protein eS30z/eS30y/eS30x
Sequence:
MKAIFNRRVVVDSSSRLTKLLANPTTHSHLNRQTFTSLYKPNQSRHFRTHYLPSSPSSPPVSRFDPSQLWRSEKIRGFFASALGNKAVKLGNLVESRVGFIGSQFPKKGFEFQRFSGFQRRGWKHWLQGLSDRDVVLGLVIANAGVFVMWRVFNQQFMMNNFMISLDNFKSGRLHTLITSAFSHIDIGHIVSNMIGLYFFGTSIARNFGPQFLLKLYLAGALGGSVFYLIHHAYMAATSPKGQGAFVRDPSRTPGLGASGAVNAIMLLDIFLHPRATLYLEFFIPVPAMLLGIFLIGKDILRITEGNSNISGSAHLGGAAVAAIAWARIRKGRFRF
Protein: 5-hydroxyisourate hydrolase (HIU hydrolase) (HIUHase) (EC 3.5.2.17) (U6C7K1)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
Sequence:
THVLNTGMGVPGAHMALSLHRMDPSTSLWNLLTTGTTNDDGRCPGLITRETFTPAVYKIRFETGQYWGSLGETSFYPYVEIVFTITDHSQKFHVPLLCSRFSY
Protein: Solute carrier family 22 member 16 (Carnitine transporter 2) (CT2) (Fly-like putative transporter 2) (FLIPT2) (Flipt 2) (Organic cation transporter OKB1) (Organic cation/carnitine transporter 6) (Q86VW1)
Organism: Homo sapiens (Human)
Function: High affinity carnitine transporter; the uptake is partially sodium-ion dependent. Thought to mediate the L-carnitine secretion mechanism from testis epididymal epithelium into the lumen which is involved in the maturation of spermatozoa. Also transports organic cations such as tetraethylammonium (TEA) and doxorubicin. The uptake of TEA is inhibited by various organic cations. The uptake of doxorubicin is sodium-independent.
Subcellular location: Cell membrane {ECO:0000269|PubMed:12089149, ECO:0000269|PubMed:20037140}; Multi-pass membrane protein {ECO:0000305}. Note=Detected in the plasma membrane of Sertoli cells and in the luminal membrane of epithelial cells in the epididymis. {ECO:0000269|PubMed:12089149}.
Interaction partners:
- Acyl-coenzyme A synthetase ACSM1, mitochondrial
Sequence:
MGSRHFEGIYDHVGHFGRFQRVLYFICAFQNISCGIHYLASVFMGVTPHHVCRPPGNVSQVVFHNHSNWSLEDTGALLSSGQKDYVTVQLQNGEIWELSRCSRNKRENTSSLGYEYTGSKKEFPCVDGYIYDQNTWKSTAVTQWNLVCDRKWLAMLIQPLFMFGVLLGSVTFGYFSDRLGRRVVLWATSSSMFLFGIAAAFAVDYYTFMAARFFLAMVASGYLVVGFVYVMEFIGMKSRTWASVHLHSFFAVGTLLVALTGYLVRTWWLYQMILSTVTVPFILCCWVLPETPFWLLSEGRYEEAQKIVDIMAKWNRASSCKLSELLSLDLQGPVSNSPTEVQKHNLSYLFYNWSITKRTLTVWLIWFTGSLGFYSFSLNSVNLGGNEYLNLFLLGVVEIPAYTFVCIAMDKVGRRTVLAYSLFCSALACGVVMVIPQKHYILGVVTAMVGKFAIGAAFGLIYLYTAELYPTIVRSLAVGSGSMVCRLASILAPFSVDLSSIWIFIPQLFVGTMALLSGVLTLKLPETLGKRLATTWEEAAKLESENESKSSKLLLTTNNSGLEKTEAITPRDSGLGE
Protein: Glycophorin-E (P15421)
Organism: Homo sapiens (Human)
Function: This protein is a minor sialoglycoprotein in human erythrocyte membranes.
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- Glycophorin-C
- Glycophorin-B
- Band 3 anion transport protein
- Kell blood group glycoprotein
- Alpha-hemoglobin-stabilizing protein
- FRAS1-related extracellular matrix protein 3
Sequence:
MYGKIIFVLLLSGIVSISASSTTGVAMHTSTSSSVTKSYISSQTNGITLINWWAMARVIFEVMLVVVGMIILISYCIR
Protein: Probable receptor-like protein kinase At2g39360 (EC 2.7.11.-) (O80623)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000305|PubMed:17644812}; Single-pass type I membrane protein {ECO:0000305|PubMed:17644812}.
Interaction partners:
- Cyclase-associated protein 1
- GPI-anchored protein LLG3
- GPI-anchored protein LLG2
Sequence:
MINLKLFLELKLCFLITLLCSSHISSVSDTFFINCGSPTNVTVNNRTFVSDNNLVQGFSVGTTDSNSGDESTLFQTARVFSDESSSTYRFPIEEHGWFLIRIYFLPLVSASQDLTTARFSVSAQNFTLIREYKPSTTSVVREYILNVTTDSLLLQFLPRTGSVSFINALEVLRLPETLIPEDAKLIGTQKDLKLSSHAMETVSRVNMGNLSVSRDQDKLWRQWDSDSAYKAHFGTPVMNLKAVNFSAGGITDDIAPVYVYGTATRLNSDLDPNTNANLTWTFKVEPGFDYFVRFHFCNIIVDPFGFERQIRFDIFVNSEKVRTIDMTEVLNGTFGAPFFVDAVMRKAKSREGFLNLSIGLVMDVSSYPVSFINGFEISKLSNDKRSLDAFDAILPDGSSSNKSSNTSVGLIAGLSAALCVALVFGVVVSWWCIRKRRRRNRQMQTVHSRGDDHQIKKNETGESLIFSSSKIGYRYPLALIKEATDDFDESLVIGVGGFGKVYKGVLRDKTEVAVKRGAPQSRQGLAEFKTEVEMLTQFRHRHLVSLIGYCDENSEMIIVYEYMEKGTLKDHLYDLDDKPRLSWRQRLEICVGAARGLHYLHTGSTRAIIHRDVKSANILLDDNFMAKVADFGLSKTGPDLDQTHVSTAVKGSFGYLDPEYLTRQQLTEKSDVYSFGVVMLEVVCGRPVIDPSLPREKVNLIEWAMKLVKKGKLEDIIDPFLVGKVKLEEVKKYCEVTEKCLSQNGIERPAMGDLLWNLEFMLQVQAKDEKAAMVDDKPEASVVGSTMQFSVNGVGDIAGVSMSKVFAQMVREETR
Protein: Nickel import ATP-binding protein NikD (EC 7.2.2.11) (P33593)
Organism: Escherichia coli (strain K12)
Function: Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_01711}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01711}.
Interaction partners:
- Nickel-binding periplasmic protein
- Nickel import ATP-binding protein NikE
- Nickel transport system permease protein NikB
- Nickel transport system permease protein NikC
- Probable D,D-dipeptide transport system permease protein DdpC
- Glutathione transport system permease protein GsiD
- Dipeptide transport system permease protein DppC
- Oligopeptide transport system permease protein OppC
- Uncharacterized ABC transporter ATP-binding protein YdcT
- Arginine transport ATP-binding protein ArtP
Sequence:
MPQQIELRNIALQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAATLGILPAGVRQTAGEILADGKPVSPCALRGIKIATIMQNPRSAFNPLHTMHTHARETCLALGKPADDATLTAAIEAVGLENAARVLKLYPFEMSGGMLQRMMIAMAVLCESPFIIADEPTTDLDVVAQARILDLLESIMQKQAPGMLLVTHDMGVVARLADDVAVMSDGKIVEQGDVETLFNAPKHTVTRSLVSAHLALYGMELAS
Protein: 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) (2-keto-3-deoxygluconokinase) (3-deoxy-2-oxo-D-gluconate kinase) (KDG kinase) (P37647)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG).
Interaction partners:
- KHG/KDPG aldolase
- Mannonate dehydratase
- Altronate dehydratase
- 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
- Phosphogluconate dehydratase
- Uronate isomerase
- D-mannonate oxidoreductase
- Starvation-sensing protein RspA
- 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
- Altronate oxidoreductase
Sequence:
MSKKIAVIGECMIELSEKGADVKRGFGGDTLNTSVYIARQVDPAALTVHYVTALGTDSFSQQMLDAWHGENVDTSLTQRMENRLPGLYYIETDSTGERTFYYWRNEAAAKFWLESEQSAAICEELANFDYLYLSGISLAILSPTSREKLLSLLRECRANGGKVIFDNNYRPRLWASKEETQQVYQQMLECTDIAFLTLDDEDALWGQQPVEDVIARTHNAGVKEVVVKRGADSCLVSIAGEGLVDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLTGGSAEDAAKRGHLTASTVIQYRGAIIPREAMPA
Protein: Uncharacterized protein (Q57ZX9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000256|ARBA:ARBA00004120}.
Interaction partners:
- Intraflagellar transport protein 122 homolog
- Intraflagellar transport protein 140
- WD repeat-containing protein 19
- Uncharacterized protein
- Intraflagellar transport protein 80
- IFT80/172/WDR35 TPR domain-containing protein
- Intraflagellar transport protein IFT88, putative
- Intraflagellar transport protein A1
- Intraflagellar transport protein 56 homolog
- Intraflagellar transport protein 57/55
Sequence:
MHLYLTKRVAIPSTVAVTAVAWNEEQGWLAVGGKGGLLKVLKIDGGGSQRGGLAMNQTLEGHETDVSVVAWNHQYRKLTSSDAGGQIIVWMLHKGMWLEEMINNRNKSTVRDLAWSVDGTKVCIVYEDGAVILGGVDGNRLWGKDLKCELTNVTWSPDDRYILFGTKSGDVQMHDSATGHLVNQVAITHQANKVPLAGLEWSSAWVDRPEPLPSLAVCYKNGRIHLLRGITDHEARVVEAGINVTGIAWNPQGTMLAVCGVPATGGASGDGGTSAQGGATGGDAGADGSASSVLTLIYNGDGVHMRTLRMNGKFCGGITWEGDGLRVAVAVDAAMYFANVRCDYKYAYFHKTVVFAYNRPDRTDSSVMFWNTRNNERVIRHIRGLLHIHACRNACLIVNAPGEERCCIVQLVNAIGCPIESRMLDMEPIVSGLNSSHVVVADEENIYIWQFRDPSVVVDALDPVSVQMSRRETHDRVVHVDDFVRADTPSALTTQTALTNDLICTVCLSEDFLFVARESGLLQLYRFNPLQLVGKAVLPCRPQSIAVNCNSTRLVLIDVVGVMRMFHIDPTTMSLAPSKLVPQPGFERKDVWNVQWAQDDPEMLAVMERSRLHIYHGTESEEPITCSTHICKFRSLKVRSLLLDELKQDPERPRREYVIDHDTRALRDAREVMQTASTRDALRYMDEHSHPKLWSLFAEHALAQLDFDSAELAFIRCGDYPAIQFVKRIKTLDDPQKQRAEIHTYYHRFDQAEKIYKDIDRKDLALELRYRLGDWFRVVQLVQEGGGDESHMRRAWENIGDFYADRQKWTKAAQYYSQSQQLHKLAHILFLQEDYDLLVQLIQNAEHDRELLLKLGEMLLSVGLGEEALRAYLAAGEPRLAVESCTQLNQWDCVMAVAEEYKLTDVSKQLGRHATRLVDSGRLSEAIGLYRKAGQHDEAARLLAGLGQRAATTNPLSAKKFYVLSALEVEKYRKKKMTLSGNGTAAVEALLDVEQSGKGQERAFDAAWRGAEAYHFFLLCQQHILNRNLVYALNVAMRLMDYDDIISPVDSYSLIALTAYLAKNYSICSKAFTRLEAAEQMDEQSQSEGGEARGAVQLQMMDMIADLDVSCRTKVGHGVGPAGGGAGGVSGTTRLDGTTTSLQLTNPSKGAVSAIQMTYPTVTLTEPRRRFADLASKIFTQHKPEDNFIDRVKCHKCEAHNKEWASACVRCQQPFHVCIYSGRSITSEEFWQCSVCHHRLLDVETDRFRNCPLCHTPLRH
Protein: Probable adenylyltransferase/sulfurtransferase MoeZ [Includes: Sulfur carrier protein CysO adenylyltransferase (EC 2.7.7.-); Sulfur carrier protein CysO sulfurtransferase (EC 2.8.1.-)] (P9WMN7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps: first, ATP-dependent activation of CysO as acyl-adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO-thiocarboxylate (CysO-COSH) (Probable). The sulfur source is unknown.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Sulfur carrier protein CysO
- Molybdopterin synthase catalytic subunit 1
- Molybdopterin synthase sulfur carrier subunit
- Molybdopterin synthase sulfur carrier subunit
- IscS-like cysteine desulfurase
- O-phosphoserine sulfhydrylase
- Probable adenylyltransferase/sulfurtransferase MoeZ
- Molybdopterin synthase catalytic subunit 2
- Thiazole synthase
- Molybdopterin synthase catalytic subunit 1
Sequence:
MSTSLPPLVEPASALSREEVARYSRHLIIPDLGVDGQKRLKNARVLVIGAGGLGAPTLLYLAAAGVGTIGIVDFDVVDESNLQRQVIHGVADVGRSKAQSARDSIVAINPLIRVRLHELRLAPSNAVDLFKQYDLILDGTDNFATRYLVNDAAVLAGKPYVWGSIYRFEGQASVFWEDAPDGLGVNYRDLYPEPPPPGMVPSCAEGGVLGIICASVASVMGTEAIKLITGIGETLLGRLLVYDALEMSYRTITIRKDPSTPKITELVDYEQFCGVVADDAAQAAKGSTITPRELRDWLDSGRKLALIDVRDPVEWDIVHIDGAQLIPKSLINSGEGLAKLPQDRTAVLYCKTGVRSAEALAAVKKAGFSDAVHLQGGIVAWAKQMQPDMVMY
Protein: Bromodomain PHD finger transcription factor (E9PE19)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
XGGGGGGHLARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNVIAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQCTLMAEMHVVLLKAVLREEDTSNTTFGPADLKDSVNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPYQEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIIEEDTENENEKKIWYYSTKVQLAELIDCLDKDYWEAELCKILEEMREEIHRHMDITEDLTNKARGSNKSFLAAANEEILESIRAKKGDIDNVKSPEETEKDKNETENDSKDAEKNREEFEDQSLEKDSDDKTPDDDPEQGKSEEPTEVGDKGNSVSANLGDNTTNATSEETSPSEGRSPVGCLSETPDSSNMAEKKVASELPQDVPEEPNKTCESSNTSATTTSIQPNLENSNSSSELNSSQSESAKAADDPENGERESHTPVSIQEEIVGDFKSEKSNGELSESPGAGKGASGSTRIITRLRNPDSKLSQLKSQQVAAAAHEANKLFKEGKEVLVVNSQGEISRLSTKKEVIMKGNINNYFKLGQEGKYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTLRLTITQLENNIPSSFLHPNWASHRANWIKAVQMCSKPREFALALAILECAVKPVVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQEEEETMQQATWVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISKTHVYRFVPKLPGNTNVNYRKSLEGTKNNMDENMDESDKRKCSRSPKKIKIEPDSEKDEVKGSDAAKGADQNEMDISKITEKKDQDVKELLDSDSDKPCKEEPMEVDDDMKTESHVNCQESSQVDVVNVSEGFHLRTSYKKKTKSSKLDGLLERRIKQFTLEEKQRLEKIKLEGGIKGIGKTSTNSSKNLSESPVITKAKEGCQSDSMRQEQSPNANNDQPEDLIQGCSESDSSVLRMSDPSHTTNKLYPKDRVLDDVSIRSPETKCPKQNSIENDIEEKVSDLASRGQEPSKSKTKGNDFFIDDSKLASADDIGTLICKNKKPLIQEESDTIVSSSKSALHSSVPKSTNDRDATPLSRAMDFEGKLGCDSESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLEPLKCELVSGESTGNCEDRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIKLKNTTDKKNNENRESEKKGQRTSTFQINGKDNKPKIYLKGECLKEISESRVVSGNVEPKVNNINKIIPENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVEDMEIETSEVKKVTSSPITSEEESNLSNDFIDENGLPINKNENVNGESKRKTVITEVTTMTSTVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSIFVLPNDDLKKLARKGGIREVPYFNYNAKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLLWASLRWDDMAAKAPPGGGTTRTETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDLCTNWYHGECVGITEKEAKKMDVYICNDCKRAQEGSSEELYCICRTPYDESQFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQSTAS
Protein: glutaminase (EC 3.5.1.2) (A0A1D8PCS7)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- pyridoxal 5'-phosphate synthase
- pyridoxal 5'-phosphate synthase
- Isoamyl acetate-hydrolyzing esterase
- Pyridoxamine 5'-phosphate oxidase Alr4036 family FMN-binding domain-containing protein
- pyridoxal kinase
- pyridoxal kinase
- Ribose-5-phosphate isomerase
- Ribokinase
- Transaldolase
- 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase
Sequence:
MTIDRSVTIGVLALQGAFREHIAYFKHLIESNPDEYAVYDFDIKEVRTKEDLELCDSLVIPGGESSSMSYIAERTELLPHLYKFVSDESKSVWGTCAGLIFLSKQLINGIENQRVLGALDIEVSRNAFGRQIDSFEQSLDFSSFIPGCTDFPTVFIRAPVVTKILNQKDSLKEGVIRSNNSYQNQAPVKVLYSLKNYDGKDHELIVAVQQGHILGTSFHPELAEDYRFHKWFLDEFVIKKSKQYIDRII
Protein: Tumor protein p63-regulated gene 1-like protein (Mossy fiber terminal-associated vertebrate-specific presynaptic protein) (Protein FAM79A) (Q5T0D9)
Organism: Homo sapiens (Human)
Function: Presynaptic protein involved in the synaptic transmission tuning. Regulates synaptic release probability by decreasing the calcium sensitivity of release.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:A8WCF8}; Peripheral membrane protein {ECO:0000250|UniProtKB:A8WCF8}. Presynaptic active zone {ECO:0000250|UniProtKB:A8WCF8}.
Interaction partners:
Sequence:
MLQLRDSVDSAGTSPTAVLAAGEEVGAGGGPGGGRPGAGTPLRQTLWPLSIHDPTRRARVKEYFVFRPGSIEQAVEEIRVVVRPVEDGEIQGVWLLTEVDHWNNEKERLVLVTEQSLLICKYDFISLQCQQVVRIALNAVDTISYGEFQFPPKSLNKREGFGIRIQWDKQSRPSFINRWNPWSTNVPYATFTEHPMAGADEKTASLCQLESFKALLIQAVKKAQKESPLPGQANGVLILERPLLIETYVGLMSFINNEAKLGYSMTRGKIGF
Protein: Aldose reductase A (ARA) (EC 1.1.1.21) (Aldehyde reductase A) (AlrA) (Q6IMN8)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. Probably affects several metabolic pathways in addition to converting glucose to sorbitol. Affects group size.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14551196}.
Interaction partners:
- Aldehyde dehydrogenase
- Aldehyde dehydrogenase
- Putative aldehyde dehydrogenase family 7 member A1 homolog
- Dihydropteridine reductase
- dihydrofolate reductase
- Sepiapterin reductase
- Probable glycerol kinase
- Aldose reductase C
- Beta-galactosidase 1
- Probable alpha-galactosidase
Sequence:
MEPSFKLSSGHKIPLVGFGTWKAETTLVGKAVEVALDAGYRHIDCAAVYLNEKEVGEAFTKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVAFEYTSNDIQTSGSTQEFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKPAANQVELHPFLSQPELKKFCDKHNIHLTAYSPLGNGAFVDNEEVGAIAKKYNKTIPNVLCKWAIQKNFSVIPKSSTPSRVAENFDLFNFEIEEADMLFLDKMDKNLRTCDPAKFWGVPLFN
Protein: Protein WWC2 (BH-3-only member B) (WW domain-containing protein 2) (Q6AWC2)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:24682284}.
Interaction partners:
- Serine/threonine-protein kinase LATS1
Sequence:
MPRRAGSGQLPLPRGWEEARDYDGKVFYIDHNTRRTSWIDPRDRLTKPLSFADCVGDELPWGWEAGFDPQIGVYYIDHINKTTQIEDPRKQWRGEQEKMLKDYLSVAQDALRTQKELYHVKEQRLALALDEYVRLNDAYKEKSSSHTSLFSGSSSSTKYDPDILKAEISTTRLRVKKLKRELSQMKQELLYKEQGFETLQQIDKKMSGGQSGYELSEAKAILTELKSIRKAISSGEKEKQDLMQSLAKLQERFHLDQNIGRSEPDLRCSPVNSHLCLSRQTLDAGSQTSISGDIGVRSRSNLAEKVRLSLQYEEAKRSMANLKIELSKLDSEAWPGALDIEKEKLMLINEKEELLKELQFVTPQKRTQDELERLEAERQRLEEELLSVRGTPSRALAERLRLEERRKELLQKLEETTKLTTYLHSQLKSLSASTLSMSSGSSLGSLASSRGSLNTSSRGSLNSLSSTELYYSSQSDQIDVDYQYKLDFLLQEKSGYIPSGPITTIHENEVVKSPSQPGQSGLCGVAAAATGHTPPLAEAPKSVASLSSRSSLSSLSPPGSPLVLEGTFPMSSSHDASLHQFTADFEDCELSSHFADISLIENQILLDSDSGGASQSLSEDKDLNECAREPLYEGTADVEKSLPKRRVIHLLGEKTTCVSAAVSDESVAGDSGVYEAFVKQPSEMEDVTYSEEDVAIVETAQVQIGLRYNAKSSSFMVIIAQLRNLHAFLIPHTSKVYFRVAVLPSSTDVSCLFRTKVHPPTESILFNDVFRVAISQTALQQKTLRVDLCSVSKHRREECLAGTQISLADLPFSSEVFTLWYNLLPSKQMPCKKNEENEDSVFQPNQPLVDSIDLDAVSALLARTSAELLAVEQELAQEEEEESGQEEPRGPDGDWLTMLREASDEIVAEKEAEVKLPEDSSCTEDLSSCTSVPEMNEDGNRKESNCAKDLRSQPPTRIPTLVDKETNTDEAANDNMAVRPKERSSLSSRQHPFVRSSVIVRSQTFSPGERNQYICRLNRSDSDSSTLAKKSLFVRNSTERRSLRVKRTVCQSVLRRTTQECPVRTSLDLELDLQASLTRQSRLNDELQALRDLRQKLEELKAQGETDLPPGVLEDERFQRLLKQAEKQAEQSKEEQKQGLNAEKLMRQVSKDVCRLREQSQKVPRQVQSFREKIAYFTRAKISIPSLPADDV
Protein: AN1-type domain-containing protein (Q19723)
Organism: Caenorhabditis elegans
Interaction partners:
- FYVE-type domain-containing protein
Sequence:
MENEQQQAQTAPSCRAGCGFFGASATEGYCSQCFKNTLKRQQDTVRLTSPVVSPSSMAATSSALKSEPSSVDMCMKAAVSVSDETAKMDCEDIINVCDQINDDSVTVAESTAPTTITVDVPVPVKKANRCHMCKKRVGLTGFSCRCGGLYCGDHRYDQAHNCQFDYKTMERETIRKNNPVVVSDKVQRI