wanglab/gogpt-training-data huggingface dataset:
Protein: Interleukin-18 receptor accessory protein (IL-18 receptor accessory protein) (IL-18RAcP) (EC 3.2.2.6) (Accessory protein-like) (AcPL) (CD218 antigen-like family member B) (IL-1R accessory protein-like) (IL-1RAcPL) (Interleukin-18 receptor accessory protein-like) (Interleukin-18 receptor beta) (IL-18R-beta) (IL-18Rbeta) (CD antigen CD218b) (Q9Z2B1)
Organism: Mus musculus (Mouse)
Function: Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:O95256}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Interleukin-18 receptor 1
- Interleukin-18
Sequence:
MLCLGWVFLWFVAGEKTTGFNHSACATKKLLWTYSARGAENFVLFCDLQELQEQKFSHASQLSPTQSPAHKPCSGSQKDLSDVQWYMQPRSGSPLEEISRNSPHMQSEGMLHILAPQTNSIWSYICRPRIRSPQDMACCIKTVLEVKPQRNVSCGNTAQDEQVLLLGSTGSIHCPSLSCQSDVQSPEMTWYKDGRLLPEHKKNPIEMADIYVFNQGLYVCDYTQSDNVSSWTVRAVVKVRTIGKDINVKPEILDPITDTLDVELGKPLTLPCRVQFGFQRLSKPVIKWYVKESTQEWEMSVFEEKRIQSTFKNEVIERTIFLREVTQRDLSRKFVCFAQNSIGNTTRTIRLRKKEEVVFVYILLGTALMLVGVLVAAAFLYWYWIEVVLLCRTYKNKDETLGDKKEFDAFVSYSNWSSPETDAVGSLSEEHLALNLFPEVLEDTYGYRLCLLDRDVTPGGVYADDIVSIIKKSRRGIFILSPSYLNGPRVFELQAAVNLALVDQTLKLILIKFCSFQEPESLPYLVKKALRVLPTVTWKGLKSVHASSRFWTQIRYHMPVKNSNRFMFNGLRIFLKGFSPEKDLVTQKPLEGMPKSGNDHGAQNLLLYSDQKRC
Protein: TIA1 cytotoxic granule-associated RNA binding protein (A0A8I6ASW3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDQTAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQVLVHLHMDSHKLNGVMSGQPKLLAFEKTVKYFNIKLLQCKIISMCLLVTSVQKSQLKTSKQLLHHLEEFRK
Protein: Pcdha6 protein (Protocadherin alpha 6) (B9EKB6)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Interaction partners:
Sequence:
MDFTTEGRLGTRCMLLSLLLLAAWEAGSGQLHYSVPEEAKHGTFVGRIAQDLGLELTELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVEVEVRDINDNPPVFSVKEQRMLIYESRLPDSLFPLEGASDADVGLNSMLTYKLSPSEYFGLDVKSNSDGNKQIRLLLKKSLDREDAPEHKLLLTATDGGKPELTGSVQLLVTVLDVNDNAPTFQHPEYEVRILENSDNGTTVIRLNASDKDEGTNSAISYSFNRLVPPKTLEQFSIDADTGEIITQGNLDFEQVDVYKIHVDATDKGHPPMVGHCTVLVKVLDENDNVPQITLTSLSLPVREDAALSTVIALISVSDLDSGSNGQVTCSLSPHVPFKLVSTFKNYYSLVLDSALDRETTADYQVVVTARDGGSPSLWTTASVSVEVADVNDNAPSFAQPDYTVFVKENNPPGAHIFTVSAMDADAQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLQFQVSARDAGVPALGSNVTLQVFVLDENDNAPTLLGPWTPGSGGVVSELVSPSVGAGQVVTKVRAVDADSGYNAWLSYELHPLAGGTRSLFRVGLYTGEISTTRALEEADAPRHRLLVLVKDHGEPALIATATVLVSLVENSQTPKASSRAQGATGQEVSLVNVNVYLIIAICAVSSLLVLTLMVYTALRCSVPPTEGVCGAGKPVLVCSSAVGSWSYSQQRRQKVCSGEGPPKTDLMAFSPSLPPCPVVGEHQDLNDDHCSRPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPEPKKQTQVSFLPRRKGEASQPRQ
Protein: Rcorf28 (A8VZX9)
Organism: Rhizobium rhizogenes (Agrobacterium rhizogenes)
Interaction partners:
Sequence:
MPTDDIVMSDPGMAAVDTSVPTRFQTDLRQFSNLLDESNIVEWVVNHAANRNACFGQDQLKISAARALTHYKRPVQEIDLLFQQVVASDKLTRLDSPDGQPLYTSTELRAAEQNTVRHVTNLSAEESFGVPGTIVDMVADRGIFTPELRGALHYLSRRNRASTMVGVAGSAKTSVLGALNEAVDRFNEEALPTEKIKLIAFVPTNRAAQELREKGLRDVATTFKAKDRTIGKNTIVVIDEMSMAKTQEIAQLIETVANATSYHPTERPKLICVGDDRQLPPVGPGDLLPIIMEQAGCYELVQPLRQLDARSRIETEKLGRDIRRDAKSAVGHYLTALEQMGLVHFVYAPPSGSNVRASDQITDRMLEEMNRVCDRYPVYDRLVMAHSNRSVNRANIALHQRFVDKSGLQDQQMSVWSSVIDSGSSESGIDEGSSRRVQQRINLVLGDRIIFSENRLQADIRNGTFATVVGLNSTEASRAENGTSAGVRITARLDGSGRTVTWTDSEFKGFTYGYAATIYKSQGATVDHAILLCDGALSDKLTYVGLTRHRSRLDVIASPLVANNVEALSAKLTQQSAPNNSIQFPALEPAAFQERSSVSNAHLLRPLDQMEISPTTPLSFQGRQESSFGENQLHEPSTSDVEMPESADLYPSAIDFEVFQSSVITTEEQMQPEFCGSESTANTSAHESHQVTIATVTNLGIAIEKRKRAAAKEEIDSRKKMARHSVSSAEEVEDITSLFERLKLATSVTNTVQPTYADVDHIIGTDGRVGPIPHREDDPGSNWELSSTNAPSNVSEKRSTKDSGEKNMASNDQKMQGADSAGSERHFSQTSIVEALQAGDHKKLVETLAATGSLVEKADAGSALKAMADAYERDIKADPEKVRMLYANRRVDVDALAKEIEKQGLASGRLSGDPVSFKAFNNKDIRFRVGDRLSVTSSYRNLIAGEAGRIEKIEGKSVTFKPDGSSQSKTFEASTGEPGDRGVKGYKIEGPMTVIGSAYELTRHDDGKRVDQIYLLNDAAHGINANSALLSKADERTQLFTSLKDTADRDILARQLGKPGSELYQDKFPALPDYTAAIDRIAKRQEVVAARGEEKTSAPIDLAPQTPPDAADAAVNNQKRIVEALQAGDHKKLVETLAATGSLVENTNLVSTLKAIAQTYERDISADPEKVRALYANKRDHVDLLAEEIEKQGLASGRLSGDPVSFKAFNNKDIRFRVGDRLSVTSSYRNLIAGEAGRIEKIEGKSVTFKPDGSSQSKTFEASTGEPGDRGVKGYKIEGPTTIIGSAYEIRNHDDGRRVDQVYVLHSAIFGSNAASALLSKADERTQVFTVQSDTADRHILASQLSKPGSELYQDKFPVSPDYAAAIDRIAKREELRAGRGEESPTVQMEPVNQTPYEAGHWTPDSQKSVVEALQAGDHKKLVETLAATGSLVEKADAGSALKAMADAYERDIKADPEKVRMLYANRRVDVDALAKEIEKQGLASGRLSGDPVSFKAFNNKDIRFRVGDRLSVTSSYRNLIAGEAGRIEKIEGKSVTFKPDGSSQSKTFEASTGEPGDRGVKGYKIEGPMTVIGSAYELTRHDDGKRVDQIYLLNDAAHGINANSALLSRADERTQLFTSLKDTADRDILARQLGKPGSELYQDKFPALPDYTAAIDRIAKRQEVVAARGEVKPIERTEAPEIPQVQATIVGETSIIRLPDRIKTNREKPQELDVVSKEGHETTGSLRQSVQESNAAPKQTSPKAANDVDRLTRDFDERIRVRGDGRGL
Protein: Keratin, type II cytoskeletal 78 (Cytokeratin-78) (CK-78) (Keratin-5b) (Keratin-78) (K78) (Type-II keratin Kb40) (Q8N1N4)
Organism: Homo sapiens (Human)
Interaction partners:
- Keratinocyte proline-rich protein
- Cornulin
Sequence:
MSLSPCRAQRGFSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEWSGGPGLSLCPPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRMSGECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIILGSGKDPVLDSCSVSGSSAGSSCHTILKKTVESSLKTSITY
Protein: Netrin-1 (F1QUK5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Neogenin
- Unc-5 netrin receptor B.
- Neogenin 1b
- Netrin receptor UNC5
- Slit homolog 1b
- Si:ch73-72b7.1.
- Draxin
- Unc-5 netrin receptor C.
- Slit homolog 1a
- Cell adhesion molecule DSCAM
Sequence:
MIRILVTCVSMVSITSMVSGARGGYGMSMFAAQSSPPDPCYDENGNPRRCIPDFVNSAFGKDVRVSSTCGSPPSRYCVVTEKGEERSRDCNICDATDPKKTHPPAYLTDLNNPHNLTCWQSENYVQYPQNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIFKSMDYGKTWVPFQFYSTQCKKMYNKPSKAAITKQNEQEAICTDSHTDMQPLTGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIKVTFNRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHASKCVKDREGNLVCECKHNTAGPECDRCKPFHYDRPWQRATAREANECVACHCNLHARRCRFNMELYKLSGRRSGGVCLNCRHNTAGRHCHYCKEGYYRDMSKAISHRRACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIAPCIKIPVAAPTSSYSSPDGPTDCDSHCKAPKGKMKVTMKKYCKKDFAVQVHVLKGDKAGEWWKFTINIISVYKQGGHRIRRGDQLLWVRAKDVACKCPKIKPGRKYLLMGSDEEEDSRGQSGVVADRGSLLIPWKDLWARRLRKFQQRDKRGKC
Protein: Transmembrane protein 107 (Q6UX40)
Organism: Homo sapiens (Human)
Function: Plays a role in cilia formation and embryonic patterning. Requires for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with GLI2 and GLI3 to pattern ventral and intermediate neuronal cell types (By similarity). During ciliogenesis regulates the ciliary transition zone localization of some MKS complex proteins.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cell projection, cilium {ECO:0000269|PubMed:26595381}. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme. {ECO:0000269|PubMed:26595381}.
Interaction partners:
- Transmembrane protein 216
- Transmembrane protein 231
- B9 domain-containing protein 1
- B9 domain-containing protein 2
- Coiled-coil and C2 domain-containing protein 2A
- Transmembrane protein 17
- Centrosomal protein of 290 kDa
- Tectonic-1
- Tectonic-2
- Meckelin
Sequence:
MGRVSGLVPSRFLTLLAHLVVVITLFWSRDSNIQACLPLTFTPEEYDKQDIQLVAALSVTLGLFAVELAGFLSGVSMFNSTQSLISIGAHCSASVALSFFIFERWECTTYWYIFVFCSALPAVTEMALFVTVFGLKKKPF
Protein: Regulator of microtubule dynamics protein 3 (RMD-3) (mRMD-3) (Protein FAM82A2) (Protein FAM82C) (Q3UJU9)
Organism: Mus musculus (Mouse)
Function: Involved in cellular calcium homeostasis regulation (By similarity). May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis (By similarity).
Subcellular location: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q96TC7}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q96TC7}. Cytoplasm {ECO:0000250|UniProtKB:Q96TC7}. Nucleus {ECO:0000250|UniProtKB:Q96TC7}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q96TC7}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250|UniProtKB:Q96TC7}. Note=In interphase localizes in the cytoplasm, and during mitosis localizes to the spindle microtubules and spindle poles. {ECO:0000250|UniProtKB:Q96TC7}.
Interaction partners:
- Vesicle-associated membrane protein-associated protein B
- Oxysterol-binding protein-related protein 5
- Oxysterol-binding protein-related protein 8
- Mitofusin-2
Sequence:
MSRLGALGGSRAGLGLLLGTAAGLGFLCVLYSQRWKRTQRHGRSHSLPNSLDYAQASERGRQVTQFRAIPGEAGDAAILPSLSQEGQEKVLDRLDFVLTSLMALRREVEELQRSLQGLAGEIVGEVRSHIEENQRVARRRRFPFARERSDSTGSSSVYFTASSGAALTDAESEGGYTTANAESDYERDSDKESGDAEDEVSCETVRMGRKDSLDLDVEAASSPAAAALEEDDSSGREDVQLVLLQADELHQGSKQDKREGFQLLLNNKLAYGSRQDFLWRLARAYSDMSDLTEEESGKKSYALNGKEEAEAALKKGDESAACHLWYAVLCGQLAEHEGISKRIQSGFSFKEHVDKAIELQPEDPRGHFLLGRWCYQVSHLNWLEKKTATALFESPLSATVQDALQSFLKAEELQPGFSKAGRVYISKCYRELGKNSEARKWMKLAQELPDVTNEDSAFQKDLEELEVILG
Protein: Nuclear receptor-binding protein (HLS7-interacting protein kinase) (MLF1 adapter molecule) (Q99J45)
Organism: Mus musculus (Mouse)
Function: May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases.
Subcellular location: Cytoplasm, cell cortex {ECO:0000269|PubMed:12176995}. Endomembrane system {ECO:0000269|PubMed:12176995}. Cell projection, lamellipodium {ECO:0000269|PubMed:12176995}. Note=Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia.
Interaction partners:
- TSC22 domain family protein 2
- TSC22 domain family protein 4
- TSC22 domain family protein 1
Sequence:
MSEGESQTVVSSGSDPKVESSSLAPGLTSVSPPVTSTTSAASPEEEEESEDESEILEESPCGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADVKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHNGLIKIGSVAPDTINNHVKTCREEQKNLHFFAPEYGEVTNVTTAVDIYSFGMCALEMAVLEIQGNGESSYVPQEAISSAIQLLEDSLQREFIQKCLQSEPARRPTARELLFHPALFEVPSLKLLAAHCIVGHQHMIPENALEEITKNMDTSAVLAEIPAGPGREPVQTLYSQSPALELDKFLEDVRNGIYPLTAFGLPRPQQPQQEEVTSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCDLMPNESIPDLAAELVQLGFISEADQSRLTSLLEETLNKFNFTRNSTLNTATVTVSS
Protein: Negative elongation factor complex member A (F7FPZ3)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MASMRESDTGLWLHNKLGATDELWAPPSIASLLTAAVIDNIRLCFHRLSSAVKLKLLLGTLHLPRRTVDEMKGALMDIIQLATLDSDPWVLMVADILKSFPDTGSLNLDLEEQNPNVQDILGELREKVSECEASAMLPLECQYLNKNALTTLAGPLTPPVKHFQLKRKPKSATLRAELLQKSTETAQQLKRSAGVPFHAKGRGLLRKMDTTTPFRSPTTPSVFSPSGNRTPIPPSRTPLQKERGVKLLDISELNTVGAGREAKRRRKTLDTEVVEKPTKEETVVENATPDYAAGLVSTQKLGSLNSEPTLPSTSYLPSTPSVVPASSYIPSSETPPAPPSREASRPPEEPSAPSPTLPTQFKQRAPMYNSGLSPATPTPAAPASPLTPTAPPAVTPTAQTPPVAMVAPQTQAPAPVQQQPKKNLSLTREQMFAAQEMFKTANKVTRPEKALILGFMAGSRENPCPEQGDVIQIKLSEHTEDLPKADGQGSTTMLVDTVFEMNYATGQWTRFKKYKPMTNVS
Protein: Leucine-rich repeat protein (C6S3E1)
Organism: Plasmodium falciparum (isolate 3D7)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MASYNVLGELTTFNEDETIITHQYSRIKKIENIEKCKKLKTLKLISNCIEKLENLENNVQLEHLELYENMIKKIENISMLINLKVLDLSFNKIKIIENLETLVNLEELYLSSNKISKIENLQNCKKLRLLELGYNKIRMIENIEHLTNLEELWLGKNKIEQINLPYLPKLKKLSVQHNRLTDICEKSIKNILCVEELYISYNKINHIIDTFKDLKHLKVFDLSYNEINNISICSYLKSLEELWLNNNNIDNLEMIKKLSTIENLKTLYLEKNKIQDNLKENYRKTIIHILPQLKQLDALPIPSSPTLQK
Protein: G-type lectin S-receptor-like serine/threonine-protein kinase SD2-5 (EC 2.7.11.1) (S-domain-2 (SD2) receptor kinase 5) (SD2-5) (Q8RWZ5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Kunitz trypsin inhibitor 3
- Probable calcium-binding protein CML22
- phosphoglucomutase
Sequence:
MRGVFIVIVTCLVFLPDPLRAGVASIGSITPGFGGSQMNYINNDGIFLESNNSAFGFGFVTTQDSVTLFTLSIIHKSSTKLIWSANRASPVSNSDKFVFDDNGNVVMEGTEVWRLDNSGKNASRIELRDSGNLVVVSVDGTSIWESFDHPTDTLITNQAFKEGMKLTSSPSSSNMTYALEIKSGDMVLSVNSLTPQVYWSMANARERIINKDGGVVTSSSLLGNSWRFFDQKQVLLWQFVFSDNKDDNTTWIAVLGNNGVISFSNLGSGASAADSSTKIPSDLCGTPEPCGPYYVCSGSKVCGCVSGLSRARSDCKTGITSPCKKTKDNATLPLQLVSAGDGVDYFALGYAPPFSKKTDLDSCKEFCHNNCSCLGLFFQNSSGNCFLFDYIGSFKTSGNGGSGFVSYIKIASTGSGGGDNGEDDGKHFPYVVIIVVVTVFIIAVLIFVAFRIHKRKKMILEAPQESSEEDNFLENLSGMPIRFAYKDLQSATNNFSVKLGQGGFGSVYEGTLPDGSRLAVKKLEGIGQGKKEFRAEVSIIGSIHHLHLVRLRGFCAEGAHRLLAYEFLSKGSLERWIFRKKDGDVLLDWDTRFNIALGTAKGLAYLHEDCDARIVHCDIKPENILLDDNFNAKVSDFGLAKLMTREQSHVFTTMRGTRGYLAPEWITNYAISEKSDVYSYGMVLLELIGGRKNYDPSETSEKCHFPSFAFKKMEEGKLMDIVDGKMKNVDVTDERVQRAMKTALWCIQEDMQTRPSMSKVVQMLEGVFPVVQPPSSSTMGSRLYSSFFKSISEDGGATTSSGPSDCNSENYLSAVRLSGPR
Protein: Myosin heavy chain, cardiac muscle isoform (P29616)
Organism: Gallus gallus (Chicken)
Function: Muscle contraction.
Subcellular location: Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Interaction partners:
Sequence:
KIKPLLKSAETEKEMANMKEEFLKLKEALEKSEARRKELEEKQVSLVQEKNDLLLQLQAEQDTLADAEERCDLLIKSKIQLEAKVKELTERVEDEEEMNSELTSKKRKLEDECSELKKDIDDLEITLAKVEKEKHATENKVKNLTEEMATLDENISKLTKEKKSLQEAHQQVLDDLQAEEDKVNTLSKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESVMDLENDKLQMEEKLKKKEFEMSQLNSKIEDEQAIVMQLQKKIKELQARIEELEEELEAERAARAKVEKQRSDLARELEELSERLEGAGGATAAQLEMNKKREAEFLKLARDLEEATLHYEATAAALRKKHADRRGEMGEQLDNLQRVKQKLEKEKSELKMEVDDLTANMEQTVKGKANAEKLWGTYEDHLNETKTKLDEMTRLMNDLTTQKTKLQSENGEFVRQLEEKESLISQLSRGKTSFTQQIEELRRQLEEETKSKNALAHALQAARHDCDLLREQYEEEQEAKAELQRALSKGNAEVAQWRTKYETDAIQRTEELEDAKKKLLARLQEAEEAIEAANAKCSSLEKAKHRLQNEQEDMMIDLEKANSAAASLDKKQRGFDKIINDWKQKYEESQAELEASQKEARSLSTELFKLKNAYEETLDHLETLKRENKNLQEEISDLTNQISEGNKNLHEIEKVKKQVEQEKSEVQLALEEAEGALEHEESKTLRFQLELSQLKADFERKLAEKDEEMQNIRRNQQRTIDSLQSTLDSEARSRNEAIRLKKKMEGDLNEMEIQLSHANRHAAEATKSARGLQTQIKELQVQLDDLGHLNEDLKEQLAVSDRRNNLLQSELDELRALLDQTERARKLAEHELLEATERVNLLHTQNTSLINQKKKLEGDISQMQNEVEESIQECRNAEQKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQKRLDEAEQIALKGGKKQIQKLESRVRELENELENELRRNSDAQKGARKFERRIKELTYQSEEDKKNLARMQDLIDKLQLKVKSYKHQAEEAEAQANLYLSKYRKQQHDLDDAEERAEIAESQVDKLRSKSRDIGMKKVDAEE
Protein: B30.2/SPRY domain-containing protein (Q55AQ4)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Retinoblastoma-binding-like protein E
- Histone-lysine N-methyltransferase set1
- Anaphase-promoting complex subunit 4-like WD40 domain-containing protein
- Carbohydrate binding domain-containing protein
- FHA domain-containing protein
- Histone H4
- Histone H3.3 type c
- Histone H3.3 type a
- Histone H3.3 type b
- CCHC-type domain-containing protein
Sequence:
MDSSLSNNNNHSYNNYNNNNTYPMINEKPHQNQQQRQNNENTEHHLINQFDNKNSASLLNQSGNYQNSMNNNNNNNNQQSYKRQHSDTSDSDLTSSSSMSSSGSGSSSESDSDTHSSSSSLSDSDSDDDRYNTNKNIQNNNNNNNNNNYNNNNNINNIINNNSNTNNSNINNNINNNNNNNNINNNINNNTNNSNTNNSNTGNSNINSSNTNNSNINNSNTNNSNINNSNTSNSNTNSNINSSNTNNSNTINNNTNNSNINNNNTNNSNINSSNSSNTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNNSNSSNNNINNSNINNSNINNSNINNNNINNINNNVSNTNNSNTNNSNIKNTNNNNTNINDHNNTTINNNNNNNNVSSSSNSSKRKNSENISKSMQTHVDTPPLQNEVRLPIIGKKPIFEFPYNISSLTWDIDHLNNLENIYCYCGKDKYKTMIRCDLCKQVFHIECIQLLEGSQQLHGDWVYRFTCSVCNEDSETFERFSKNWVDILEITLFNLTQSKIEQLEKLERKSNGNGGGGSPPITFNDLKSSINANSSMDEINFNNLKSNSINQLKKGVYFHLEEEIIPFIEKNWNLLCSDKKKKAQWQKQLMPALNSGRIFKSGFINYRKNGMWALGTDQLLLKDNSMFKDKVLAPLHRNRKKKKTSEEERDKYITKLLLVPTKEGTYIPTIEYDTLCIAKTNSAPQIILRDNTFLSVTSHEGYRMARSSFPCVYGEWYYEIEVLEPSKIDHSQQQQQQLLQQQQQQQQNSPSHSYQSQAQYYQQLQQQYQLQQQQLQQKQQQQEQKPYACRLGWSSPKGDCQANVGYDYFSYSYRSTQGDIFHNARSKPYGETYKQGDVIGFYINLPLEEDDINKEKIKEFPNINQLDIYEMISNDLSLPSDQPLTPLKGSFIQFFKNGLSPGPAFTNIGKSFYYPAASLYMGATVKFNFGPDFKYPPPSHLNPKPFCLINNNNNK
Protein: Datilografo, isoform A (Datilografo, isoform C) (GH02610p) (Q7KQN5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Protein lin-28 homolog
Sequence:
MKLRCFNQAQTSHSWHPRSVFRVVSSCPPDRKKRPSPASWQICIGHLLTNYLGMFKMDSADFWQQARAPFGLQTALHQYSSPPNQQPISHHALHHSVPQENEQLAGVQPEGPAAGSGVVGNNSSMAISGTNSTVGSKAESSHIPQQHSEQQSYGSDSFRGTQSPQLSSHHLLFNAAAAAAAAVHLKSTAMQNNLSPIGDQVQNNLRNYGQGSLNALCGIKPKQEMDAKTPLQPLDECPHPLVQAQAQSQYGGDYYDVADPQAREISEGRALIIGLGAPSTVSTDDAQSSAPSHQLAGTGRALQTHQCKPMSPGTVGSSNLGAGRRSAPTTISKTFSQGQQSPQHSTTPSGGSTTPDIKYNNDKMANEIQLQLSRSSSAAAISERTLEECWSTLQRLFMHKSAMQQIQQQIPRVGLGTHGVTGSANLGGSITPSSDTKPHQCQQCMKSFSSNHQLVQHIRVHTGEKPYKCSYCDRRFKQLSHVQQHTRLHTGERPYKCHLPDCGRAFIQLSNLQQHLRNHDAQVERAKNRPFHCNICGKGFATESSLRTHTSKELQLHLGVLQQHAALIGGPNATSCPVCHKLFLGTEALVDHMKHVHKEKSPPPGGSASSQFSELNQIVTGNGNGTGSSNEQIATQCTTESNSHQATVGSSLIDSFLGKRRTANHPCPVCGKHYVNEGSLRKHLACHAENSQLTNSLRMWPCSVCQAVFTHENGLLTHMESMRMDPKHQFAAQYVLSRAAAEQRERESLLAVTLAASSGASTRIGIADAGNVLPTGAHNSDGSNSKCPSPSANSECSSNGRLSSSTTSDQDQDIDHGLSENENSNQNNIGSSTNNNNNCTSNNNASSHKMAELRLPGTGQYTMDAELHVANRMSLMAAAAAAVAASRPQDGVDTSAVPSAAVQAAVVNLAAAMRMNNSSNGATPYQQHHADHTQAHQTHILQHAHPHHHQQQQAPQHQQQQLSHLLVHTHPSNSNSRSQSSPNINVPSLQNESTAASIAMNMNVHMMRGSLDPDPSLGGMHGIEVLHQHQQQHHHHHHHHTSNYPQHAVTPTNQHTHPHPQTHQTAHHHTSPETALRMHQAEAILRSHTEAAFRLATGSGPDTGVKCEADQNQLNSNNAGNAGGNSGGNSQQHRFHASSNHQENQRPSDS
Protein: Glutamate racemase (EC 5.1.1.3) (Q3XZW8)
Organism: Enterococcus faecium (strain ATCC BAA-472 / TX0016 / DO)
Interaction partners:
Sequence:
MKKRMIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARCPYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILPGTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEYHSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGEVSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK
Protein: Ubiquitin-activating enzyme E1, putative (EC 6.3.2.19) (Q57XC5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Ubiquitin-conjugating enzyme E2, putative
- Polyubiquitin, putative
- Ubiquitin-activating enzyme E1, putative
- Ubiquitin-conjugating enzyme E2, putative
- Ubiquitin-conjugating enzyme E2, putative
- E2 ubiquitin-conjugating enzyme
- Ubiquitin-conjugating enzyme E2, putative
- Ubiquitin-ribosomal protein eL40 fusion protein
- Ubiquitin-like protein, putative
- Ubiquitin/ribosomal protein S27a, putative
Sequence:
MTSEEQRRQLYNRQEYVVGTETQAKYGCTDVLVVGACGLGAEIIKNLTLTGVRSIKVLDNGLATLQDLGTNFFLTPADMGKPRAEVVAARAQELNRFVSVTAVDVPLHEVIPAVHVVVFVNQRTTLLLAENAMARKHNVKFVACESRGVAGCVFVDAGPSFTVLDPDGEETVVCVVTNISRDGVVSLHEDKKHECEVGGRVFLTGLVSPESLNSTVDPFALHNGRATTECAQGDNSPTGASSSLRLFEVSEVVSPFHLRLKDFGAIVGDSPIETGYACYLHTTKRKVLVGFKDLQLSVMQPEFVTLFDSEKKMMAPMTLHALFRAVHSHGKLPTTPIEVRDVLKAAEAYFSSGNDQVHNGFDVETAESILSVMHGRLNPMDCFIGGLASQEVLKVCSGKFTPLRQWLYYDARELLVARGEMSETGCVSTAPGGSRYDGQIAVLGSSFQSFLSRQRVFIVGAGALGCELIKNVACMGFGAVSITDMDTIEMSNLSRQFLFRNSHIGQQKSKVAGEAARAINGDLKVSAYLEKVAQETENVFDEKFWESHSLVLNALDNVESRKYVDARCLFFRKPLFESGTLGPKCNVQCVIPYCTESYSSSYDPPEKSIPLCTLKNFPNVIEHTIQWARDNFDAVFFSTPSDVNGYLEDPTTFASNLERDPGTKSIVLKAVRDALVQWPKDAADCVRMARSLFHEYFNSSFRQLLHNLPLDKRNDNGDLFWSGAKKPPKPQEFSVDSELNVSFVYHCAKLLAQVYNLSAFTLSVKEVAELAMQVAVPGFVPREARFETNEAENKEGAAAQLVGDLTMQDLPPVSQFNSRRMNPLVFEKDDPNNSHMDYITACSNLRATAYSIPPADVHYTKRIAGRIIPAMVTTTALVTGLVGIEALKYLLLAHRENGAQGLAKANPITEKVQEEYLSLYRNAFVNVALPFMAFSDPIAAPAKTVPMPDGSSVRWGIWDRIDINEGRDITVKELVSILEKRHQLEIFIIALPCGKMVYSQFGNVKDRDKPVSVVVREKTKGEEKDELSCICFVATGSIGDNDVDIPLIYYRYKDF
Protein: Uroporphyrinogen decarboxylase (UPD) (URO-D) (EC 4.1.1.37) (P06132)
Organism: Homo sapiens (Human)
Function: Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway. Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme. In vitro also decarboxylates pentacarboxylate porphyrinogen I.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P70697}.
Interaction partners:
- Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial
- Protoporphyrinogen oxidase
- Uroporphyrinogen-III synthase
- Porphobilinogen deaminase
- Delta-aminolevulinic acid dehydratase
- Ferrochelatase, mitochondrial
- Hereditary hemochromatosis protein
- 5-aminolevulinate synthase, non-specific, mitochondrial
- Molybdenum cofactor biosynthesis protein 1
- 5-aminolevulinate synthase, erythroid-specific, mitochondrial
Sequence:
MEANGLGPQGFPELKNDTFLRAAWGEETDYTPVWCMRQAGRYLPEFRETRAAQDFFSTCRSPEACCELTLQPLRRFPLDAAIIFSDILVVPQALGMEVTMVPGKGPSFPEPLREEQDLERLRDPEVVASELGYVFQAITLTRQRLAGRVPLIGFAGAPWTLMTYMVEGGGSSTMAQAKRWLYQRPQASHQLLRILTDALVPYLVGQVVAGAQALQLFESHAGHLGPQLFNKFALPYIRDVAKQVKARLREAGLAPVPMIIFAKDGHFALEELAQAGYEVVGLDWTVAPKKARECVGKTVTLQGNLDPCALYASEEEIGQLVKQMLDDFGPHRYIANLGHGLYPDMDPEHVGAFVDAVHKHSRLLRQN
Protein: Ribosomal RNA-processing protein 43 (Q381C6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
- Exosome component CSL4
- Ribosomal RNA processing protein 4
- Ribosomal RNA processing protein 45
- Exosome complex exonuclease RRP40
- RNasePH-like protein exosome-associated protein 1 Rrp42 homologue
- Elongation factor 1-alpha, putative
- ATP-dependent DEAD/H RNA helicase, putative
- Ribosomal RNA processing protein 6
- Exosome-associated protein 4
- CCHC-type domain-containing protein
Sequence:
MSLPPATGAVELASFQQHVHQFLVQNKRLDGRPLDALREPHILRDSKGGDGLLASTLYTDNTGMCLNCTVSGVFGPPPSDQPDEGRLTVDVAAPFFQSHSTDQVAAALREVARFVRSTIISCMDLTELNIINGEACWVLQVELVILNADGGLRAAALHAVVAAIHNMLLPRSRLPNGDEVESRRLRFHTIPVAVTIGVYKLGASGVRFLMDTNAAEESVVDGLLTVVLSDENGIITFVQSGSYSISSLLLTGAVNEFALRSAALRAAILKPSVAAAKINGSKNSVTDPHPLKEG
Protein: Late transcription elongation factor OPG110 (Viral late gene transcription factor 4) (VLTF-4) (P07242)
Organism: Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
Function: Involved in the co-transcriptional or post-transcriptional endoribonucleolytic cleavage that generates sequence-homogeneous 3' ends during late transcription. Involved in postreplicative transcription elongation on intermediate and late genes. Also involved in DNA replication and in multiple steps of virion morphogenesis. Required both for inclusion of virosoplasm into crescents as well as for maturation of immature virions (IV) into mature virions (MV).
Subcellular location: Virion. Host cytoplasm {ECO:0000269|PubMed:25855734}. Note=Early during viral infection, diffusely localizes within the cytoplasm. Following DNA replication, localizes specifically to virus factories. {ECO:0000269|PubMed:25855734}.
Interaction partners:
Sequence:
MAWSITNKADTSSFTKMAEIRAHLKNSAENKDKNEDIFPEDVIIPSTKPKTKRATTPRKPAATKRSTKKEEVEEEVVIEEYHQTTEKNSPSPGVSDIVESVAAVELDDSDGDDEPMVQVEAGKVNHSARSDLSDLKVATDNIVKDLKKIITRISAVSTVLEDVQAAGISRQFTSMTKAITTLSDLVTEGKSKVVRKKVKTCKK
Protein: aspartate transaminase (EC 2.6.1.1) (A1ZAA5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Glutamate dehydrogenase, mitochondrial
- Malate dehydrogenase
- Malate dehydrogenase, mitochondrial
- Aspartate aminotransferase
- alanine transaminase
- Malate dehydrogenase
- Malate dehydrogenase
- Tyrosine aminotransferase
- 4-hydroxyphenylpyruvate dioxygenase
- Protein henna
Sequence:
MFIILKRLNYPGLLQNFQLSTMSIYADVPKGPAIEVFALTQAFKDDSNPNKVNLSVGAYRTDAGVPWVLPVVRKTEISIASDEQVNHEYLPVTGLETFTNAATELVLGADSPAIKENRAFGVQTISGTGALRVAADFLHTQLNRNVVYYSNPTWENHHKIFCDAGFTTVKSYRYWDQNKRELDFKNMLADLNDAPPGAVIILHACAHNPTGIDPTQEQWTELADLMEKKKLFPLFDSAYQGFASGDPDRDAWAARYFVQRGFELFICQSFAKNFGLYCERTGNLAVVQKNGATKAAVHSQLTLLIRGQYSNPPAYGARIVSKVLNTPELRKEWMASIQAMSSRIREMRTALRDKLVALGTPGTWDHIVNQIGMFSYTGLNESHVRVLIDQYHIYLLKTGRISMSGLNKGNVEYVAKAIHAAVTGSGESASCPCENKL
Protein: Man1-Src1p-carboxy-terminal domain protein (F4KHI7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus inner membrane {ECO:0000256|ARBA:ARBA00004540}.
Interaction partners:
Sequence:
MDSIPRKRPKSETRTGRTPKSSSSSSPIRSMLEPPQSLFPSKGEFFTLLKVLLVACAVAFTCNFLSKSLSSNPSKSFCDSNFNPIDSDLDICEPCPINGECYQGKLQCNLGYKNQRNLCVEDGEINESTKKLVGYFERKVCESYAHNECYGTGTIWVPENDVWTELRSNSFLSNLDESAYNFLKGKAVEGVTELLEKRTNSNGIDELKCPESVAKSYKPLTCRLHQWILRHILIISSSCAMLVGSAMLRRRIQRKQCFSRRVEELYDQVCDFLEENAVASNSAETSNCEPWVIASWLRDYLLLPRERRDPLLWTKVEELIKEDSRIDRYEKLLKGEKKVVWEWQVEGSLSLSKLKKQRETQKKVRKSIDSSTSLQEYYNRRIAETSS