wanglab/gogpt-training-data huggingface dataset:
Protein: Actin-like protein MamK (EC 3.6.1.-) (Magnetosome cytoskeleton protein MamK) (Q2W8Q6)
Organism: Paramagnetospirillum magneticum (strain ATCC 700264 / AMB-1) (Magnetospirillum magneticum)
Function: Protein with ATPase activity which forms dynamic cytoplasmic filaments (probably with paralog MamK-like) that organize magnetosomes into long chains running parallel to the long axis of the cell (Probable). Turnover of MamK filaments is probably promoted by MamK-like, which provides a monomer pool. Forms twisted filaments in the presence of ATP or GTP. Serves to close gaps between magnetosomes in the chain. Interaction with MCP10 is involved in controlling the response to magnetic fields, possibly by controlling flagellar rotation. Expression in E.coli yields a filament in the cell's longitudinal axis; the protein nucleates at several sites and one extremity of the filament is located at the cell pole.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16373532, ECO:0000305|PubMed:20471399}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:16373532, ECO:0000269|PubMed:17085581, ECO:0000269|PubMed:20471399, ECO:0000269|PubMed:21883528, ECO:0000269|PubMed:24957623, ECO:0000269|PubMed:27481925}. Magnetosome membrane {ECO:0000305|PubMed:16303747}; Peripheral membrane protein {ECO:0000305}. Note=Tagged protein forms straight lines extending along most of the cell associated with its inner curvature, in the correct position to be filaments that are seen associated with magnetosomes (PubMed:16373532, PubMed:17085581, PubMed:20471399, PubMed:21883528, PubMed:27481925). Colocalizes in filaments with paralog MamK-like (PubMed:24957623). {ECO:0000269|PubMed:16373532, ECO:0000269|PubMed:17085581, ECO:0000269|PubMed:20471399, ECO:0000269|PubMed:21883528, ECO:0000269|PubMed:24957623, ECO:0000269|PubMed:27481925}.
Interaction partners:
- Cell shape-determining protein MreC
- Magnetosome protein MamH
- Probable membrane transporter protein MamO
- Magnetosome formation protease MamE
- Magnetosome-associated protein MamJ
- Magnetosome protein MamM
- Magnetosome protein MamL
- Magnetosome protein MamI
- Magnetosome protein MamN
- Cytoskeleton protein RodZ-like C-terminal domain-containing protein
Sequence:
MSEGEGQAKNRLFLGIDLGTSHTAVMSSRGKKFLLKSVVGYPKDVIGLKLLGRPYVVGDEAFEMRSYLDIRYPLQDGVLSEISDRDIEVARHLLTHVVKSAEPGPNDEICAVIGVPARASAANKALLLKMAQEVVHTALVVSEPFMVGYGLDKLINTIIVDIGAGTTDICALKGTVPGPEDQVTLTKAGNYVDERLQNAILERHPELQMNVNVACAVKEQFSFVGTPTEVASFEFRAAGKPVRADVTEPVKIACEALMPDIIESIETLLRSFQPEYQATVLQNIVFAGGGSRIRGLAAYVKEKLRPFGDANVTCVKDPTFDGCRGALRLAEELPPQYWRQLGDVSGS
Protein: OSJNBa0065O17.4 protein (Q7XPS7)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MASAPPVQEEPLQPGTNHFRSLLAAAVRSISWSYAIFWSISTSCPGVLTWNDGFYNGVVKTRKISNSADLTAGQLVVQRSEQLRELYYSLLSGECDHRARRPIAALSPEDLADTEWYYVVCMTYSFQPGQGLPGKSYASNASVWLRNAQSADSKTFLRSLLAKTIICIPFTSGVLELGTTDPTFIIAYACHNMEQVLEDPKLVNRIVAYFQELQFPICLEVLMSTSPSPNETEDADIVSEGLITHNAIEEGQMVVSDECVSNANRDPITMEIDELYSIYEDLDLDMDLDLDTVRFLEDNGWPVNPSSFQLVPASSTEAVAAAAAANDVDGVANSQVSCFMAWKSAKSNEMAVPVVTGIESQKLLKKVVDCGARMSTGRGSRAALTQESGIKNHVISERRRREKLNEMFLILKSIVPSIHKVDKASILEETIAYLKVLEKRVKELESSSEPSHQRATETGQQRRCEITGKELVSEIGVSGGGDAGREHHHVNVTVTDKVVLLEVQCRWKELVMTRVFDAIKSLCLDVLSVQASAPDGLLGLKIQAKFACSGSVAPGMISEALQKAIGG
Protein: Mediator of RNA polymerase II transcription subunit 13 (Mediator complex subunit 13) (Protein SCA1) (Suppressor of RNA polymerase B SSN2) (P38931)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II RPB1 at serines 2 and 5.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 12
- RNA polymerase II holoenzyme cyclin-like subunit
- Meiotic mRNA stability protein kinase SSN3
- Mediator of RNA polymerase II transcription subunit 16
- Mediator of RNA polymerase II transcription subunit 5
- Mediator of RNA polymerase II transcription subunit 2
- Mediator of RNA polymerase II transcription subunit 19
- Mediator of RNA polymerase II transcription subunit 17
- Mediator of RNA polymerase II transcription subunit 21
- Mediator of RNA polymerase II transcription subunit 7
Sequence:
MSSDASTYRLEDVLSSFYRVEKIKKINYHQYISKAQNDQWSIQMEFMLRKQDPKTLVALLSRDLWCFSINDDPVPTPPAIEHKPVSPDKIGTFTADYSKPNLPPHYALFLKALRRKIYINLALGSHNKLIQFGNACISLSGVPNYLVQLEPHLFVNGDLTVSLCAKNMGLVPMKEENLEESFLSKHALYLAPSGIRMHLAPASKQGYLITPPKHTELLLTTLSVSHGINLQNKKNLKWVAVVPDLGHLNGHTPTIASYLTPLLEAKKLVWPLHLIFAQPVADIENSTSGDPSEFHCLQDALDAIDDFIQLKQTAAYRTPGSSGVLSSNIAGTNPLSSDGAYTEQFQHYKNNSISSQPASYHSVQETNKISPKDFSPNFTGIDKLMLSPSDQFAPAFLNTPNNNINENELFNDRKQTTVSNDLENSPLKTELEANGRSLEKVNNSVSKTGSVDTLHNKEGTLEQREQNENLPSDKSDSMVDKELFGEDEDEDLFGDSNKSNSTNESNKSISDEITEDMFEMSDEEENNNNKSINKNNKEMHTDLGKDIPFFPSSEKPNIRTMSGTTKRLNGKRKYLDIPIDEMTLPTSPLYMDPGAPLPVETPRDRRKSVFAPLNFNPIIENNVDNKYKSGGKFSFSPLQKEEALNFDISMADLSSSEEEEDEEENGSSDEDLKSLNVRDDMKPSDNISTNTNIHEPQYINYSSIPSLQDSIIKQENFNSVNDANITSNKEGFNSIWKIPQNDIPQTESPLKTVDSSIQPIESNIKMTLEDNNVTSNPSEFTPNMVNSEISNLPKDKSGIPEFTPADPNLSFESSSSLPFLLRHMPLASIPDIFITPTPVVTISEKEQDILDLIAEQVVTDYNILGNLGIPKIAYRGVKDCQEGLITTTMLQLFSTFDRLNGNDTISKFYNMKQPYVFVKKHHELIKVKHDSQPFIKFLNFRPPNGIKNFKSLLLSSSFKEDCLSFAPTLSQTYINQELGFCELLKLTNEDPPGLMYLKAFDKNKLLLLAAQIVSYCSNNKNSIKNVPPILIILPLDNATLTELVDKANIFQVIKNEVCAKMPNIELYLKVIPMDFIRNVLVTVDQYVNVAISIYNMLPPKSVKFTHIAHTLPEKVNFRTMQQQQMQQQQQQQQQQQNNSTGSSSIIYYDSYIHLAYSRSVDKEWVFAALSDSYGQGSMTKTWYVGNSRGKFDDACNQIWNIALNLASKKFGKICLILTRLNGILPDDELMNWRRLSGRNIHLAVVCVDDNSKISFIDEDKLYPSFKPIYKDTRFGGRMDMTRLYDYEIRDIDQDIHGIVFQHPFPLAHSQHRCAIRSGALIKFKKCDGDTVWDKFAVNLLNCPHSDSTQLLETILEEFRNLAALNVWYGLSDGEDGHIPWHILAVKKMMNTLVHTRVKIANTSAATVHTATSSSIILSDK
Protein: GH04238p (Q9W1H6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDTLLIAILAIGLLHRDALCYPTRDESEDKIIVLQNEEMEPTILDCDYEVEESPKFITVKWYRDDKSIYQWIFGTPPYAIPEFRNEIDSTYESSTEPSKQYSSLALINPTIATTGDYKCVVQTSLNTFSSHQRVQVIDLRNYTLELSHKTIHNETQLNCTVTNVYPRPTITIISNDMDVVKREPMVYENEEGYFDGSAVVAAYDTDDDPDAYQCVVSFEGYGKNLTTVATSAAAGRSHVDFSLWLFCFLYYLLCKLKVLA
Protein: Nucleoporin nup124 (Nuclear pore protein nup124) (Q09904)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Nucleoporins may be involved in both binding and translocation of the proteins during nucleocytoplasmic transport. In S.pombe it is required for the nuclear localization of retrotransposon tf1.
Subcellular location: Nucleus, nuclear pore complex {ECO:0000269|PubMed:10409764}.
Interaction partners:
- Importin subunit beta-1
- Importin subunit alpha-2
- Nucleoporin nup107
- Nucleoporin nup186
- Nucleoporin nup146
- mRNA export factor mex67
- Nucleoporin nup44
- Nucleoporin nup85
- GTP-binding nuclear protein spi1
- Nucleoporin nup132
Sequence:
MPPVSKNTRTSSKTVKKPYDPPQGSSRPFFTVLKRAFSSVLHPFTSGLDEKASGTASKDRKSGRAGTKSLLTPELTPHYLGKSPRIIRVSNRSHVRTIDGIEEKVHTNTFEPRKPKQKQDYTNSPTLFKRHDELSLKSLNSLHPSSALSKKLGSTSQHQIATPKSSASLLNILRSLHDEQKNTLNISSVKQDRITEANPTCEKRKPSRSPSPMLSKKKSVARASENEPSAKQNKSFSGNDSHKSLTDIRDKENGETEVSAKNHVPHRSSRRRRRHQRLIPIIYETLEQMDLRKPVLVNAEVQTDSNPGNTMFIDKQDIYHRLSTPTSRKRQTLEKGHIKAFSAVDEDLDEIFACEDDVHYTALPKQNPKSERILEPIIASPKDNTSDKGLLTKSAPTFEELQASITPKPVKTSPNDTALTLANAEDNKTFEHQPLSKDTEAPKSQFSSSPTKESTTRKSEVEPPSPSKEIKSSHFSVPEFKFEPKTEATTDKKLNVPKFEFKPTATADVQTNRLKENEPKPTFFAQLPSKTQETPSITENKPSFFSQLSPKREETEKKDNAPSAPASTSGFSFGGFAPKTLEEKEETKAPTFNFSLNNASSTQDTTKPTLQFNFGSSFGKPTSNIFNDKKTSENGLASSTVASESKPSAPESKPSSGFGNTAGSSPFSFNLTKESKEVPPTNSFSFAKKGKDEANDSLSAKASTPFSFAKPNTENVTTTAPQFSFNFTKPNTDAKTNLLPEKTFNEEAVKQKETEKEVPPTGPKASEIKDSVSSNNAVPSSTFNFVSPFAAVSEKTNENNIPNDTTKTNGNATKRTLEQTEDAKPFAFSFGSTTEQANKKASTSNETTKPQLDTSSKTDGVTANAPFSFASAFNAPKPSTNTADGKDSASNLTTPSPAFSFGNNSGVKASSNNNPSTNSSTAPFSFGTSNKPAFSFGSATSKTTSEGTAPAASASAPAPTTSAFSFGASNSSMNKEENTPMAKDAGDTAPASGFKSGFSFGANNSPQPASMFGTSTPAPSSAFAFGNQSGTNPAAPAGFGGITNTATNNPPSTGFTFTPSNAGSTAAPMFGAGNTPNPSGSINNASQAFAFGSGEPSNPASNPPSTGFSFGAATPSAFNASASQSPAPNGIQFNLGSSNSQTNAPPGRKIAVPRSRRKR
Protein: Prostate tumor-overexpressed gene 1 protein (M0QY25)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU369088}. Nucleus {ECO:0000256|RuleBase:RU369088}. Cell membrane {ECO:0000256|RuleBase:RU369088}. Cytoplasm, perinuclear region {ECO:0000256|RuleBase:RU369088}. Note=Translocates from the cytoplasm to the nucleus at the onset of S-phase. Also localizes to lipid rafts. {ECO:0000256|RuleBase:RU369088}.
Interaction partners:
Sequence:
MRSPAVPTPARGQLGVAFVLLPPHSEGARVFGALGPIGPSSPGLTLGGLAVSEHRLSNKLLAWSGVLEWQEKRRPYSDSTAKLKRTLPCQAYVNQGENLETDQWPQKLIMQLIPQQLLTTLGPLFRNSQLAQFHFTNRDCDSLKGLCRIMGNGFAGCMLFPHISPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVSAIRQVITTRKQAVGPGGVNSGPVQIVNNKFLAWSGVMEWQEPRPEPNSRSKRWLPSHVYVNQGEILRTEQWPRKLYMQLIPQQLLTTLVPLFRNSRLVQFHFTKDLETLKSLCRIMDNGFAGCVHFSYKASCEIRVLMLLYSSEKKIFIGLIPHDQGNFVNGIRRVIANQQQVLQRNLEQEQQQRGMGG
Protein: Putative solute carrier family 19 member 4 (Folate transporter-like protein C2orf83) (Solute carrier family 19 member 4, pseudogene) (Q53S99)
Organism: Homo sapiens (Human)
Interaction partners:
- Homeobox protein notochord
- Leucine-rich repeat and death domain-containing protein 1
Sequence:
MEDYALTFGINPFIALMIQPIVTMTVVDNQGLGLPVDIQHKAKPSPKASQMLPPDLGPPSFQNLLSPSEKLEPWDPGMRKLTVQTCGLTFIHPAGHGLCHPTAEASAETLSSTALNRPSVREGACNEKSTENKKPQDSVLWSHSRWFQGN
Protein: Methyl-accepting chemotaxis protein Aer (Aerotaxis receptor Aer) (Q9I3F6)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Chemotactic transducer for aerotaxis.
Subcellular location: Cell inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Probable purine-binding chemotaxis protein
- Chemotaxis protein CheA
- Chemotaxis protein methyltransferase 1
- Chemotaxis protein CheA
- Chemotaxis protein CheW
- Protein-glutamate methylesterase/protein-glutamine glutaminase 1
- Probable chemotaxis protein
- Protein-glutamate methylesterase/protein-glutamine glutaminase 2
- Chemotaxis protein methyltransferase 2
- Chemotaxis protein CheA
Sequence:
MRNNQPITQHERVYPAEQRLITTTNLKGIITYCNEAFIDISGFSREELMSAPHNLIRHPDVPPAVFAHMWTTLKAGRPWMGIVKNRCKNGDHYWVSAYVTPIYDQGAVVGYESVRVKPTAEQIQRAEALYRRLGAGKPAIPRRDRWLPVLLDWLPFILISQIGFLIGIWLNSWWGFILAGLLAVPLGLAGLRWQKRGLKRLMRLAEQTTSDPLIAQMYTDSRGDQARLEMAILSQDARLKTCLTRLQDTAEYLTEQARQADTLAHHSSAGLEQQRAETEQVATAVNEMAATTQEVANNVQLTADATQKANELTSRGRDIAAETRNAIQRLSESVGETGAAVSRLAQDSNEIGGVVDVIKGIADQTNLLALNAAIEAARAGDQGRGFAVVADEVRSLAQRTAASTEQIHHLIAKLQNTANDAVHTMESGLQQAEAGVQRVLEADSALVGISEAVSNITEMTTQIAAAAEEQSAVAEEINRNISTIAALAEQTSDEALRTAKLSEELTTTAQSQYSLVERFNR
Protein: Tubulin alpha chain (Q4GYY5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Nucleoside diphosphate kinase-like domain-containing protein
- Tubulin beta chain
- ODAD1 central coiled coil region domain-containing protein
- Cilia- and flagella-associated protein 45
- Zeta tubulin
- Epsilon tubulin
- TOG domain-containing protein
- Cytoplasmic dynein 2 heavy chain 1
- Dynein heavy chain, cytosolic, putative
- Cytoplasmic dynein 2 heavy chain 1
Sequence:
MREAICIHIGQAGCQVGNACWELFCLEHGIQPDGAMPSDKTIGVEDDAFNTFFSETGAGKHVPRAVFLDLEPTVVDEVRTGTYRQLFHPEQLISGKEDAANNYARGHYTIGKEIVDLCLDRIRKLADNCTGLQGFLVYHAVGGGTGSGLGALLLERLSVDYGKKSKLGYTVYPSPQVSTAVVEPYNSVLSTHSLLEHTDVAAMLDNEAIYDLTRRNLDIERPTYTNLNRLIGQVVSSLTASLRFDGALNVDLTEFQTNLVPYPRIHFVLTSYAPVISAEKAYHEQLSVSEISNAVFEPASMMTKCDPRHGKYMACCLMYRGDVVPKDVNAAVATIKTKRTIQFVDWSPTGFKCGINYQPPTVVPGGDLAKVQRAVCMIANSTAIAEVFARIDHKFDLMYSKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGAESADMDGEEDVEEY
Protein: V-set and immunoglobulin domain-containing protein 1 (Cell surface A33 antigen) (Glycoprotein A34) (Q86XK7)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MVFAFWKVFLILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEMEPISIYFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHPEVGIIVGALIGSLVGAAIIISVVCFARNKAKAKAKERNSKTIAELEPMTKINPRGESEAMPREDATQLEVTLPSSIHETGPDTIQEPDYEPKPTQEPAPEPAPGSEPMAVPDLDIELELEPETQSELEPEPEPEPESEPGVVVEPLSEDEKGVVKA
Protein: Pentatricopeptide repeat-containing protein At4g39620, chloroplastic (Protein EMBRYO DEFECTIVE 2453) (Q9SV96)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Essential for embryo development.
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Interaction partners:
- Protein FLOWERING LOCUS T
Sequence:
MDYLLTSPSSLRFSDFISSIPKETDHKWLRFSVNLGDARRSTRTRITCGAISSRRKLAERESAERENRVLVRSLMSRISDREPLVKTLDKYVKVVRCDHCFLLFEELGKSDKWLQCLEVFRWMQKQRWYIPDNGVYSKLISVMGKKGQTRMAMWLFSEMKNSGCRPDASVYNALITAHLHTRDKAKALEKVRGYLDKMKGIERCQPNVVTYNILLRAFAQSGKVDQVNALFKDLDMSPVSPDVYTFNGVMDAYGKNGMIKEMEAVLTRMRSNECKPDIITFNVLIDSYGKKQEFEKMEQTFKSLMRSKEKPTLPTFNSMIINYGKARMIDKAEWVFKKMNDMNYIPSFITYECMIMMYGYCGSVSRAREIFEEVGESDRVLKASTLNAMLEVYCRNGLYIEADKLFHNASAFRVHPDASTYKFLYKAYTKADMKEQVQILMKKMEKDGIVPNKRFFLEALEVFGSRLPGSGSENRKSTRSSRSRDSPKGRGGNQLTEFQDKDNKHVFRAVQDCRKNYLENLSGHDKGSRDESRKPSQEKQPLFASDQNNMMIKEKKELFTRVL
Protein: Zinc finger CW-type PWWP domain protein 2 (Q504Y3)
Organism: Homo sapiens (Human)
Function: Histone methylation reader which binds to non-methylated (H3K4me0), monomethylated (H3K4me1), dimethylated (H3K4me2) and trimethylated (H3K4me3) 'Lys-4' on histone H3. The order of binding preference is H3K4me3 > H3K4me2 > H3K4me1 > H3K4me0.
Interaction partners:
- Histone H3.3C
- Histone H3.2
- Histone H3-7
- Histone H3.1t
- Histone H3.1
- Histone H3.3
- Abnormal spindle-like microcephaly-associated protein
- Dual specificity protein kinase TTK
- Kinetochore protein NDC80 homolog
Sequence:
MDKEKLDVKIEYCNYAMDSSVENMYVNKVWVQCENENCLKWRLLSSEDSAKVDHDEPWYCFMNTDSRYNNCSISEEDFPEESQLHQCGFKIVYSQLPLGSLVLVKLQNWPSWPGILCPDRFKGKYVTYDPDGNVEEYHIEFLGDPHSRSWIKATFVGHYSITLKPEKCKNKKKWYKSALQEACLLYGYSHEQRLEMCCLSKLQDKSETHDKVAALVKKRKQTSKNNIEKKKPKFRKRKRKAILKCSFENVYSDDALSKENRVVCETEVLLKELEQMLQQALQPTATPDESEEGHGEEINMGEKLSKCSPEAPAGSLFENHYEEDYLVIDGIKLKAGECIEDITNKFKEIDALMSEF
Protein: Probable N-acetylmuramidase (EC 3.2.1.17) (Autolysin) (Lysozyme) (Peptidoglycan hydrolase) (A2RHZ5)
Organism: Lactococcus lactis subsp. cremoris (strain MG1363)
Function: Hydrolyzes the cell wall of L.lactis and M.lysodeikticus. Required for cell separation during growth.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Secreted 45 kDa protein
- Serine protease Do-like HtrA
- Endolysin
- Putative penicillin-binding protein 1a
- Gamma-glutamyl-diamino acid-endopeptidase
- Immunogenic secreted protein homolog
- Putative polysaccharide deacetylase
- Endo-1,4-beta-xylanase D
- ABC transporter nucleoside-binding protein BmpA
- Possible surface protein
Sequence:
MPVSRVKVKNRHLKKKTKKPLAFYKPATKFAGAVLIAGTLTTTHELLLQQTSPMVQAATNSSEVFIESIAASAKPVADANGLYPSVMIAQAILESNWGSSQLSRAPYYNLFGIQGTYQGKSVVFKTQEYLNGKWVTKDMPFRVYPSFNQSFQDNAYVLKTTNFGNGPYYAKAWRANAATYQDATAALTGRYATDPSYGASLNRIISQYNLTRFDGASSAGNTNSGGSTTTITNNNSGTNSSSTTYTVKSGDTLWGISQRYGISVAQIQSANNLKSTIIYIGQKLVLTGSASSTNSGGSNNSASTTPTTSVTPAKPTSQTTVKVKSGDTLWALSVKYKTSIAQLKSWNHLSSDTIYIGQNLIVSQSAAASNPSTGSGSTATNNSNSTSSNSNASIHKVVKGDTLWGLSQKSGSPIASIKAWNHLSSDTILIGQYLRIK
Protein: Putative syntaxin-2 (Q20574)
Organism: Caenorhabditis elegans
Function: Potentially involved in docking of synaptic vesicles at presynaptic active zones.
Subcellular location: Membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}.
Interaction partners:
- Synaptobrevin-1
- Putative syntaxin-4
- Syntaxin-1A homolog
- Alpha-soluble NSF attachment protein
- V-SNARE coiled-coil homology domain-containing protein
- Charged multivesicular body protein 4b
- Synaptosomal-associated protein
- Lethal giant larvae homologue 2 domain-containing protein
- Vesicle-trafficking protein SEC22b
- t-SNARE coiled-coil homology domain-containing protein
Sequence:
MRDRLNEFQSRVTDRFDEVELSPARPPSAAEYVDRRFEEVRNAIASVRGEIEKLRRDQQHVLALTIADPRDKNILENQIGTIRRRTGDLRKLVRQAEDDFLEFTKQVQSVTEKRMRQNQLELLKDNLNKLINLFNETHQDYKSRVSVRVRRQLQTVGQDLTDEDINRIMENSGSEQLFFREVNPLSVSGQAAYEDVKKRHGEIKDLENNIAMLEEIFLDLQHLTEAQDEMVTNIDNNVENGLEQVKQGSANVKTAVEYKKSAMRKKICVAAILITILLILIIVAIILAVVLSRGNNNNK
Protein: SET domain-containing protein (Q5AWX2)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
Sequence:
MPIAVQDPTPATPTTVPGKADAKSHPQPTHPGLLHVQRSAQAFGSSAISEVSLPAGALFAKITTATPATKAYTSVQVSRDAHIELNSDLVYCNHSCDPTLNFDMGKMEVRVVDNRPLKKGDQLTFFYPSSEWEMDQPFQCTCGAGEKCKGFIKGAKGLGRDGLKGYWLNAHIEELVQEEEQKKNADGQ
Protein: Sesquiterpene synthase 14b (ShTPS14b) ((+)-thujopsene synthase TPS14b) (EC 4.2.3.79) ((E)-alpha-bisabolene synthase TPS14b) (EC 4.2.3.-) ((E)-beta-farnesene synthase TPS14b) (EC 4.2.3.47) ((E)-gamma-bisabolene synthase TPS14b) (EC 4.2.3.59) ((Z)-beta-farnesene synthase TPS14b) (EC 4.2.3.-) (Alpha-acoradiene synthase TPS14b) (EC 4.2.3.-) (Alpha-cederene synthase TPS14b) (EC 4.2.3.-) (Beta-acoradiene synthase TPS14b) (EC 4.2.3.-) (Beta-bisabolene synthase TPS14b) (EC 4.2.3.-) (Beta-myrcene synthase TPS14b) (EC 4.2.3.15) (Limonene synthase TPS14b) (EC 4.2.3.-) (Terpinolene synthase TPS14b) (EC 4.2.3.113) (G8H5N1)
Organism: Solanum habrochaites (Wild tomato) (Lycopersicon hirsutum)
Function: Sesquiterpene synthase involved in the biosynthesis of volatile compounds. Mediates the conversion of (2E,6E)-farnesyl diphosphate ((EE)-FPP) into (+)-thujopsene, beta-bisabolene, alpha-cederene, beta-acoradiene, (E)-gamma-bisabolene, (Z)-alpha-bisabolene, (Z)-beta-farnesene and (E)-beta-farnesene, and of (2Z,6Z)-farnesyl diphosphate ((ZZ)-FPP) into (E)-gamma-bisabolene, (E)-alpha-bisabolene, (E)-beta-farnesene, (Z)-beta-farnesene, beta-bisabolene, beta-acoradiene and alpha-acoradiene. Can act with a low efficiency as a monoterpene synthase with geranyl diphosphate (GPP) as substrate, thus producing beta-myrcene, limonene and terpinolene.
Interaction partners:
Sequence:
MNQLAMVNTTITRPLANYHSSVWGNYFLSYTPQLTEISSQEKRELEELKEKVRQMLVETPDNSTQKLVLIDTIQRLGVAYHFENHIKISIQNIFDEFEKNKNKDNDDDLCVVALRFRLVRGQRHYMSSDVFTRFTNDDGKFKETLTKDVQGLLNLYEATHLRVHGEEILEEALSFTVTHLKSMSPKLDNSLKAQVSEALFQPIHTNIPRVVARKYIRIYENIESHDDLLLKFAKLDFHILQKMHQRELSELTRWWKDLDHSNKYPYARDKLVECYFWAIGVYFGPQYKRARRTLTKLIVIITITDDLYDAYATYDELVPYTNAVERCEISAMHSISPYMRPLYQVFLDYFDEMEEELTKDGKAHYVYYAKIETNKWIKSYLKEAEWLKNDIIPKCEEYKRNATITISNQMNLITCLIVAGEFISKETFEWMINESLIAPASSLINRLKDDIIGHEHEQQREHGASFIECYVKEYRASKQEAYVEARRQITNAWKDINTDYLHATQVPTFVLEPALNLSRLVDILQEDDFTDSQNFLKDTITLLFVDSVNSTSCG
Protein: Tetraspanin-4 (Tspan-4) (Novel antigen 2) (NAG-2) (Transmembrane 4 superfamily member 7) (O14817)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000269|PubMed:25342562, ECO:0000269|PubMed:34439793}; Multi-pass membrane protein.
Interaction partners:
- Growth/differentiation factor 15
Sequence:
MARACLQAVKYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCCLEFSESCGLHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILGLTFAMTMYCQVVKADTYCA
Protein: Synaptogyrin 3 (A0A8I6AUM8)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MSPFPTLSYGGRASGKDQGGGAGLRPWRMDLVGGAGSAPPRAPPPQPTRAPGRRRQRQQHPQHQQPQHQPWEVSGRAGRWDKRTEGTGPAMEGASFGAGRAGAAFDPVSFAQRPQTLLRVVSWVFSIAVFGPIVNEGYVNSDSGPELRCVFNGNAGACRFGVVLGLGAFIACVAFLLLDVRFQQISSVRDRRRAVLLDLGFSGVWSFLWFVGFCFLTNQWQRTAPGPGTAQAGDAARAAIAFSFFSILSWIWSWEASHGCRSQCVQTAVPAVWLCLAGVPAAH
Protein: Histone H2A type 2-B (H2A-clustered histone 21) (Q8IUE6)
Organism: Homo sapiens (Human)
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular location: Nucleus. Chromosome.
Interaction partners:
- Histone H4
- Histone H2B type 1-O
- Histone H3.2
- Histone H2B type 1-M
- Histone H2A type 2-A
- Histone H3.3
- Histone H2A type 2-C
- Histone H1.0
- Histone H2A type 1
- Actin-like protein 6A
Sequence:
MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTESHKPGKNK
Protein: Protein DMP9 (AtDMP9) (Protein DUO1-ACTIVATED UNKNOWN 2) (Q9FK96)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in membrane remodeling.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:20712629}; Multi-pass membrane protein {ECO:0000255}. Vacuole membrane {ECO:0000269|PubMed:20712629}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Protein GAMETE EXPRESSED 2
- Transcription factor DUO1
- Protein RALF-like 4
- Protein HAPLESS 2
- Oligopeptide transporter 8
- At4g35700
- Zinc finger protein ZAT3
- Zinc finger protein ZAT2
- P-loop containing nucleoside triphosphate hydrolases superfamily protein
- At1g10770
Sequence:
MEKTEESVGIRVYTATPPQKPSPSPPSRSPKPVLISSLPSLPSGAAAGGGRGRKRRMVAQGVQKTVSKTSMLVNFLPTGTLLMFEMVLPSIYRDGDCNGINTLMIHLLLLLCAMSCFFFHFTDSFKASDGKIYYGFVTPRGLAVFMKPPPPEFGGGDVIAEAEIPVTDDRYKLTVNDFVHAVMSVLVFMAIAFSDRRVTGCLFPGKEKEMDQVMESFPIMVGIVCSALFLVFPTTRYGVGCMTG
Protein: Apurinic-apyrimidinic endonuclease 1 (AP endonuclease 1) (EC 3.1.21.-) (P50525)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: DNA repair enzyme that cleaves apurinic/apyrimidinic (AP) sites and removes 3'-blocking groups present at single strand breaks of damaged DNA. Provides back-up AP endonuclease (APE) activity to apn2 together with uve1.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- DNA-
- Endonuclease III homolog lyase)
- Uracil-DNA glycosylase
- Flap endonuclease 1
- DNA repair protein rad16
- UV-damage endonuclease
- Adenine DNA glycosylase
- Mating-type switching protein swi10
- DNA polymerase zeta catalytic subunit
- Probable tyrosyl-DNA phosphodiesterase
Sequence:
MCAINKAYLLTKFYISANSCAFFVKSQRKWTSPDLSEDVAQKFLETASEMKFDASKQVLVHGSYLINMANADEQKREQAFNCFVDDLKRCERLGVGLYNFHPGSTASCTKEEGINNLAECINRAHEETKSVIIVTENMAGQGNCLGGTFDDFAALKSKIKNLDRWRVCLDTCHTFAAGYDIRTEESYKKVIDEFDEKVGAKYVSGWHLNDSKAPLGSNRDLHENIGLGFLGLEPFRLIMNDSRWDGIPLVLETPAKSPEQWKKEVELLRFMVGKSSDDVELMKESARLSNLGAASRKEHLNKFEKKEAKKDRKKKSKDGDQTTLLLRKKQKLGNAEVKSLDE
Protein: Transcription factor GTE1 (Bromodomain-containing protein GTE1) (Protein GLOBAL TRANSCRIPTION FACTOR GROUP E1) (Protein IMBIBITION-INDUCIBLE 1) (Q84XV2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription activator that plays a role in the promotion of seed germination by both negatively and positively regulating the abscisic acid (ABA) and phytochrome A (phyA) transduction pathways, respectively.
Subcellular location: Nucleus {ECO:0000269|PubMed:12969431}.
Interaction partners:
- At1g61215
- Vacuolar-sorting receptor 5
- TRF-like 10
- Protein SABRE
- RAF-like serine/threonine-protein kinase 24
- Histone H4
- Lectin-domain containing receptor kinase VI.4
Sequence:
MSVHVKEEPVLVPNCDVENTELAVFNGNGESELENFGTCVDEITDRVNQLEQKVVEVEHFYSTKDGAAQTNTSKSNSGGKKIAISQPNNSKGNSAGKEKSKGKHVSSPDLMRQFATMFRQIAQHKWAWPFLEPVDVKGLGLHDYYKVIEKPMDLGTIKKKMESSEYSNVREIYADVRLVFKNAMRYNEEKEDVYVMAESLLEKFEEKWLLIMPKLVEEEKKQVDEEAEKHANKQLTMEAAQAEMARDLSNELYEIDLQLEKLRESVVQRCRKLSTQEKKGLSAALGRLSPEDLSKALKMVSESNPSFPAGAPEVELDIDVQTDVTLWRLKVFVQEALKAANKSSGGTNAQNNNNTGTGEINKNNAKRRREISDAINKASIKRAKKA