wanglab/gogpt-training-data huggingface dataset:
Protein: Prostaglandin D2 receptor (PGD receptor) (PGD2 receptor) (Prostanoid DP receptor) (Q13258)
Organism: Homo sapiens (Human)
Function: Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity). Involved in PLA2G3-dependent maturation of mast cells. PLA2G3 is secreted by immature mast cells and acts on nearby fibroblasts upstream to PTDGS to synthesize PGD2, which in turn promotes mast cell maturation and degranulation via PTGDR (By similarity).
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Prostaglandin D2 receptor 2
- Prostaglandin-H2 D-isomerase
- Histone-lysine N-methyltransferase EZH2
- Sister chromatid cohesion protein PDS5 homolog B
- WD repeat-containing protein 5
- Hematopoietic prostaglandin D synthase
Sequence:
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
Protein: Allergin-1 (Allergy inhibitory receptor 1) (Mast cell antigen 32) (MCA-32) (Mast cell immunoglobulin-like receptor 1) (Q7Z6M3)
Organism: Homo sapiens (Human)
Function: Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:20526344}; Single-pass type I membrane protein {ECO:0000269|PubMed:20526344}.
Interaction partners:
Sequence:
MWSHLNRLLFWSIFSSVTCRKAVLDCEAMKTNEFPSPCLDSKTKVVMKGQNVSMFCSHKNKSLQITYSLFRRKTHLGTQDGKGEPAIFNLSITEAHESGPYKCKAQVTSCSKYSRDFSFTIVDPVTSPVLNIMVIQTETDRHITLHCLSVNGSLPINYTFFENHVAISPAISKYDREPAEFNLTKKNPGEEEEYRCEAKNRLPNYATYSHPVTMPSTGGDSCPFCLKLLLPGLLLLLVVIILILAFWVLPKYKTRKAMRNNVPRDRGDTAMEVGIYANILEKQAKEESVPEVGSRPCVSTAQDEAKHSQELQYATPVFQEVAPREQEACDSYKSGYVYSELNF
Protein: Sin3A, isoform J (A0A126GUN9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00810}.
Interaction partners:
Sequence:
MMKRTRVDEVQFGTRPVPQTSGGVGVGVVGVTGGGPTSGGGGTATVGVNTTGVTIGTVVPSAHNATISGIGSIHHRILTPQHGGAQTIAYLPSTTPTATNLKTTTSIVDSTTAGGPVGAGAQVAVGVGSAAGGGGVVVSTGSTGTQTLQYTTSYSVASIQAGGTLKANTADGANTVQIHVTGGGAANNPASAQTVSSSSQTGTIRQRTISGTQTVATAVGNLATISQQQPVQQSPLGKAQTPPSSVVANSIPVGGTTPPQGQSGNATPRLKVEDALSYLDQVKYQYADQPQIYNNFLDIMKEFKSHCIDTPGVIERVSTLFKGHTELIYGFNMFLPPGYKIEIHSDALGCSVPVVSMPSPPGAPTSTGTVHMLTGNSSMSGAGHIAIKTTNAATLTPAAGAGAAAAAAAVAQIQSAGAVNLMTHGGASLTQTTIHALQQATPPQSQSPGGGHVHVSVTNSTAANAVVPGQPGISVSAHNVPQNYSRDRERATITPTGQVAGAAANVNASASIVVGGPPTPNSLSELSPHGGAGGGPGAGAAQHNLHHIQQAHQSILLGETGQQNQPVEFNHAITYVNKIKNRFQNQPAKYKKFLEILHDYQREQKVMKEGSLNQGKMLTEQEVYTQVAKLFGQDEDLLREFGQFLPDATNHQSGQYMSKSASVHNDHGKRPTATLSGGAHITMSSASPAPSGSPLHLGATTLPQIDKSAHAAAIGNLSAVNTSVSIKTYNNNQQQQNHVIGSGLNATRNDILFEKDYHAGLQQQAHQRGAGVGGHHHLAGTAAGANIGRPGVGASVMVSYDKEHRNNHHVQKYVGHAPNQNLTHGHNAKKSPSYGIPSVIGSMPHISDNSLDRSSPGISYATPPLPSGPHGQHNSGSATRRPGDDSLVGHYASGAPPAKRPKPYCRDVSFSEASSKCTISDAAFFDKVRKALRSPEVYDNFLRCLTLFNQEIVSKTELLGLVSPFLMKFPDLLRWFTDFLGPPSGQPAGGLIDGMPLAATQRQGGGSSNSSHDRGTSHQSAAEYVQDVDLSSCKRLGASYCALPQSTVPKKCSGRTALCREVLNDKWVSFPTWASEDSTFVTSRKTQFEETIYRTEDERFELDLVIEVNSATIRVLENLQKKMSRMSTEELSKFHLDDHLGGTSQTIHQRAIHRIYGDKSGEIITGMKKNPFVAVPIVLKRLKVKEEEWREAQKTFNKQWREQNEKYYLKSLDHQAINFKPNDMKALRSKSLFNEIETLYDERHDQEDDAMEPFGPHLVLPYKDKTILDDAANLLIHHVKRQTGIQKQEKQKIKQIIRQFVPDLFFAPRQPLSDDERDDAFPFLVDDNTKMDVDSPLGRTESSTRNAKSTPSESASPARSNASTSSVTPAGIKKETDDSKATTGSFAPASSATASSATPVDDATPSTSSAAAAASAASSSTVSGTEGKPKDDPLSSHKEEGAGSTSSGVATSPRQAQDTAGAGVDVEIKLEHPADFSNPKLLPPHAHGQREDESYTLFFANNNWYLFLRLHAILCDRLHVMYERARLLAIEEERCRVNRRESTATALRLKPKPEIQVEDYYPTFLDMLKNVLDGNMDSNTFEDTMREMFGIYAYISFTLDKVVSNAVRQLQYCVTERAALDCVELFATEQRRGCTGGFCRDAHKTFDREMSYQRKAESILNEENCFKVYIYKIDCRVTIELLDSEPEEVDKPAALKAQKFSKYVERLANPALGGGGNTGRSDSALGNDSVVDGSDIKTEADEDTAERHQTITCRTNEETEPKVHTLIKCSIPSTNMNMHKNRHYVK
Protein: unspecific monooxygenase (EC 1.14.14.1) (Q5GLZ0)
Organism: Mus musculus (Mouse)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004586}. Microsome membrane {ECO:0000256|ARBA:ARBA00004524}.
Interaction partners:
- Cytochrome P450 1A2
- Cytochrome P450 2U1
- Cytochrome P450 2E1
- Epoxide hydrolase 1
- Arachidonate 12-lipoxygenase, 12R-type
- Polyunsaturated fatty acid lipoxygenase ALOX15
- Polyunsaturated fatty acid lipoxygenase ALOX8
- Polyunsaturated fatty acid 5-lipoxygenase
- Cytochrome P450 7A1
- Cytochrome P450 4A12B
Sequence:
MVLGVFLGLLLTCLLLLSLWKQNSQRRNLPPGPTPLPIIGNILQLDLKDISKSLRNFSKVYGPVFTLYLGKKPAVVLHGYKAVKEALIDHGEEFAGRGTFPVADKFIRRCGVVFSSGRTWKEMRRFSLMTLRNFGMGKRSIEDRVQEEARCLVDELRKTKGVPCDPTFILGCAPCNVICSIVFQNRFDYKDQEFLTFIDILNENVEILSSPWIQVCNNFPAIIDYLPGRHRKLLKNFDFAKHYFLAKVIQHKESLDINNPRDFIDCFLIKMEQEKHNPKTEFTCENLIFTASDLFAAGTETTSTTLRYSLLLLLKYPEVTAKVQAEIDCVIGRHRSPCMQDRHSMPYTDAVLHEIQRYIDLLPTSLPHAVTRDVKFREYLIPKGTTVIASLTSVLYDDKEFLNPERFDPSHFLDESGKFKKSDYFFPFSTGKRICVGEGLARTELFLFLTTILQNFNLKSPVDLKDLDTTPVANGFVSVPPKFQICFISI
Protein: NFKB inhibitor interacting Ras like 1 (NFKB inhibitor interacting Ras-like 1, isoform CRA_a) (G5E9P3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLYDTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEATIVVLGNKIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLPGRKNKGNSNSEN
Protein: Prosaposin (Sulfated glycoprotein 1) (SGP-1) [Cleaved into: Saposin-A; Saposin-B-Val; Saposin-B; Saposin-C; Saposin-D] (Q61207)
Organism: Mus musculus (Mouse)
Function: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling.
Subcellular location: [Prosaposin]: Secreted {ECO:0000269|PubMed:23690594}. Note=Secreted as a fully glycosylated 70 kDa protein composed of complex glycans. {ECO:0000269|PubMed:23690594}.; SUBCELLULAR LOCATION: Lysosome {ECO:0000250|UniProtKB:P07602}.
Interaction partners:
- Prosaposin receptor GPR37
- Lysosomal acid glucosylceramidase
- G-protein coupled receptor 37-like 1
- Galactocerebrosidase
- Progranulin
- Proactivator polypeptide-like 1
- Lysosome-associated membrane glycoprotein 1
- Cathepsin D
- Acid ceramidase
- Sortilin
Sequence:
MYALALFASLLATALTSPVQDPKTCSGGSAVLCRDVKTAVDCGAVKHCQQMVWSKPTAKSLPCDICKTVVTEAGNLLKDNATQEEILHYLEKTCEWIHDSSLSASCKEVVDSYLPVILDMIKGEMSNPGEVCSALNLCQSLQEYLAEQNQKQLESNKIPEVDMARVVAPFMSNIPLLLYPQDHPRSQPQPKANEDVCQDCMKLVSDVQTAVKTNSSFIQGFVDHVKEDCDRLGPGVSDICKNYVDQYSEVCVQMLMHMQDQQPKEICVLAGFCNEVKRVPMKTLVPATETIKNILPALEMMDPYEQNLVQAHNVILCQTCQFVMNKFSELIVNNATEELLVKGLSNACALLPDPARTKCQEVVGTFGPSLLDIFIHEVNPSSLCGVIGLCAARPELVEALEQPAPAIVSALLKEPTPPKQPAQPKQSALPAHVPPQKNGGFCEVCKKLVLYLEHNLEKNSTKEEILAALEKGCSFLPDPYQKQCDDFVAEYEPLLLEILVEVMDPGFVCSKIGVCPSAYKLLLGTEKCVWGPSYWCQNMETAARCNAVDHCKRHVWN
Protein: Protein IFH1 (Ribosomal RNA-processing protein 3) (P39520)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Controls the pre-rRNA processing machinery in conjunction with FHL1. Could convert FHL1 from a repressor to an activator.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Pre-rRNA-processing protein FHL1
- U3 small nucleolar RNA-associated protein 22
- DNA-binding protein RAP1
- Ribosomal RNA-processing protein 7
- Transcription factor SFP1
- ARS-binding factor 1
- Casein kinase II subunit beta'
- High mobility group protein 1
- Transcriptional regulatory protein TOD6
- Casein kinase II subunit beta
Sequence:
MAGKKSPRKSTINHSTHSGKLPANIKRLIKKGESDTKSRQSPPTLSTTRPRRFSLIYSSESSLSDVSDSDKNKSTNPHKIKRKAKNISNNSQGKKSKLIQRQIDNDDEGTESSDYQAVTDGEESENEEEESEEEEEDDDEDDDDDDDDGSDSDSDSETSSDDENIDFVKLTAQRKKRAMKALSAMNTNSNTLYSSRENSNKNKSVKLSPKKENEEEQKEEKEKEKEEQQKQQESNKKEVNGSGTTTTQQALSFKFKKEDDGISFGNGNEGYNEDIGEEVLDLKNKENNGNEEDKLDSKVMLGNNDELRFPNISESDESEYDIDQDAYFDVINNEDSHGEIGTDLETGEDDLPILEEEEQNIVSELQNDDELSFDGSIHEEGSDPVEDAENKFLQNEYNQENGYDEEDDEEDEIMSDFDMPFYEDPKFANLYYYGDGSEPKLSLSTSLPLMLNDEKLSKLKKKEAKKREQEERKQRRKLYKKTQKPSTRTTSNVDNDEYIFNVFFQSDDENSGHKSKKGRHKSGKSHIEHKNKGSNLIKSNDDLEPSTHSTVLNSGKYDSSDDEYDNILLDVAHMPSDDECSESETSHDADTDEELRALDSDSLDIGTELDDDYEDDDDDSSVTNVFIDIDDLDPDSFYFHYDSDGSSSLISSNSDKENSDGSKDCKHDLLETVVYVDDESTDEDDNLPPPSSRSKNIGSKAKEIVSSNVVGLRPPKLGTWETDNKPFSIIDGLSTKSLYALIQEHQQLREQHQRAQTPDVKREGSSNGNNGDELTLNELLNMSELEDDSPSHTDDMENNYNDAINSKSTNGHAADWYEVPKVPLSAFRNKGINAYEEDEYMIPANSNRKVPIGYIGNERTRKKIDKMKELQRKKTEKKRQLKKKKKLLKIRKQRQKAIKEQETMNLQLGINGHEIIGNNNSHSDINTGTDFTTNENTPMNELPSHAPEDASLIPHNSDLAVDSNTRKNSTKSVGLDEIHEILGKDENDLLSVGDINGYDAQEGHVIEDTDADILASLTAPVQFDNTLSHENSNSMWRRRQSMVEAAAENLRFTKNGLFSESALADIEGIMGNDVNHSFEFNDVLQ
Protein: Stathmin (Q6PBU3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MTLAAYRDKVKELPLVSLLCSCINSNRAENPTYKAEDAVDLNWCVIKEMEVIELNKRTSGQAFEVILKPPSFDVAPELNTSIPQRKDPSLEEIQKKLEAAEERRKFQEAEMLKHLAEKREHEREVIQKAFEENNNFIKNAKEKLEQRMEANKENREALLAAMLERLQEKDKHAEEVRKNKELKEEACR
Protein: AT3g53990 (AT3g53990/F5K20_290) (Adenine nucleotide alpha hydrolases-like superfamily protein) (Q9M328)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Transducin/WD40 repeat-like superfamily protein
- UDP-sugar pyrophosphorylase
- Adenine nucleotide alpha hydrolases-like superfamily protein
- HSP20-like chaperones superfamily protein
- Protein BOBBER 2
- Jacalin-related lectin 36
- Tetratricopeptide repeat protein SKI3
- Vesicle-associated protein 4-1
- Small nuclear ribonucleoprotein SmD1b
- Pentatricopeptide repeat-containing protein At2g20710
Sequence:
MPKDRNIGIAMDFSESSKNALKWAIENLADKGDTIYIIHTLPLSGDESRNSLWFKSGSPLIPLAEFREPEIMEKYGVKTDIACLDMLDTGSRQKEVHVVTKLYWGDAREKLVDAVKDLKLDSIVMGSRGLSALQRIIMGSVSSFVIQHAPCPVTVVKDNE
Protein: 1,3-beta-glucan synthase (EC 2.4.1.34) (1,3-beta-D-glucan-UDP glucosyltransferase) (G5EB86)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Glycogen [starch] synthase
- Alpha,alpha-trehalose-phosphate synthase
- Synthase subunit of trehalose-6-phosphate synthase/phosphatase complex
- Probable glucan endo-1,3-beta-glucosidase eglC
- Glucan 1,3-beta-glucosidase D
- Probable glucan 1,3-beta-glucosidase A
- glucan 1,3-beta-glucosidase
- Rhamnogalacturonase A/B/Epimerase-like pectate lyase domain-containing protein
- Large subunit of trehalose 6-phosphate synthase
- glycogenin glucosyltransferase
Sequence:
MSGYPQGSGYQHGNYDDGYDHQGHGDAYYQDDHHAQAGYYDNQDYGDGYYDRGGYGDHGYQHDGYYDAGHHDDYYGDQYYAQGGQGRGRHGRDSEEESETFSDFTMRSETARAADMDYYGRGDERYNSYTDSQYGHGGYGYRPPSSQVSYGGNRSSGASTPVYGMDYGNGLPAGQRSREPYPAWASDGQVPVSKEEIEDIFIDLVNKFGFQRDSMRNMYDHLMTQLDSRASRMTPNQALLSLHADYIGGDNANYRRWYFAAHLDLDDAVGFANMKLGKADRKTRKARKAAKKKAQENPEDVEGTLEALEGDNSLEAAEYRWKTRMNRMSQHERVRQLALYLLCWGEANQVRFLPEALCFIFKCADDFYNSPECQNRVEPVEEFTYLNEIITPLYQYCRDQGYEILDGKYVRRERDHNQIIGYDDMNQLFWYPEGIERIVLEDKTRLVDIPTAERWTKLKEVNWKKVFFKTYKETRSWFHLVTNFNRIWVIHLGAFWFFTAYNAPTIYTKNYRQQLNNKPPGAYYWSAVGFGGALVSFIQIMATIFEWMYVPRRWAGAQHLTKRLLFLLLVFVINLAPGVVVFGFSSVLPGKVPLVVGIVHFFIALATFFFFSIMPLGGLFGSYLKKHGRQYVASQTFTASFPRLKGNDMWMSYGLWVCVFGAKLAESYFFLTLSIKDPIRYLSPYHVHQCAGVKYIGDKICYYQPQILLGLMFFMDLTLFFLDSYLWYIICNTIFSVARSFYLGVSIWSPWRNIFSRLPKRIYSKVLATTDMEIKYKPKVLISQVWNAIIISMYREHLLAIDHVQKLLYHQVPSEQEGKRTLRAPTFFVSQEDQSFKTEFFPRGSEAERRISFFAQSLSTPMPEPLPVDNMPTFTVLIPHYSEKILLSLREIIREDEPYSRVTLLEYLKQLHPHEWDCFVKDTKILADETSQFNGDYEKNEKDAAKSKIDDLPFYCIGFKSAAPEYTLRTRIWSSLRSQTLYRTVSGMMNYSRAIKLLYRVENPEVVQMFGGNSEKLEHELERMARRKFKICVSMQRYAKFTKEERENTEFLLRAYPDLQIAYLDEEPPANEGEEPRLYSALIDGHCELLENGMRKPKFRIQLSGNPILGDGKSDNQNHSIIFYRGEYIQVIDANQDNYLEECLKIRSVLAEFEELTTDNVSPYTPGVASSSEAPVAILGAREYIFSENIGVLGDVAAGKEQTFGTLFARTLAQIGGKLHYGHPDFLNGIFMTTRGGISKAQKGLHLNEDIYAGMNAMVRGGRIKHCEYFQCGKGRDLGFGSILNFTTKIGTGMGEQMLSREYYYLGTQLPLDRFLSFYYAHPGFHINNMFIMLSVQMFMIVLINLGALKHETINCNYNSDLPITDPLMPTFCAPLTPIINWVNRCVISIFIVFFISFVPLAVQELTERGLWRMATRLAKHFGSFSFMFEVFVCQIYSNAVHQNLSFGGARYIATGRGFATARIPFGVLYSRFAGPSIYTGFRLLIMLLFSTSTTWTASLIWFWVSLLALCISPFLFNPHQFAWNDFFIDYRDYIRWLSRGNSRSHASSWIGFCRLSRTRITGYKRKLLGVPSEKGSGDVPRARITNIFFSEIVAPLVLVAVTLVPYLYINSRTGVSADVDGGNDPHDAILRIAIVAFGPIGINAGVAAVFFGMACCMGPILSMCCKKFGAVLAAIAHAIAVIILLVIFEVMFFLEHWSWPRCVMGMIAMAAIQRFVYKLIIALALTREFKHDQSNIAWWTGKWYNMGWHSLSQPGREFLCKITELGYFSADFVIGHLLLFIMLPALCVPYIDKFHSVILFWLRPSRQIRPPIYSLKQSKLRKRRVVRFAILYFAMLILFLVLLIAPLIARNQDLNLKMSGILLELMQPLDSNNNDTMTSYTGSGVPKGMEPIASPSSYLTNLNN
Protein: Bile salt hydrolase/transferase (BSH/T) (Bile acid amine N-acyltransferase) (EC 2.3.1.-) (Bile salt hydrolase) (BSH) (Chenodeoxycholoyltaurine hydrolase) (EC 3.5.1.74) (Choloylglycine hydrolase) (EC 3.5.1.24) (Conjugated bile acid hydrolase) (EC 3.5.1.-) (Q9KK62)
Organism: Bifidobacterium longum
Function: Bile salt hydrolase that catalyzes the deconjugation of glycine- and taurine-linked bile salts, which occurs naturally in the intestines of humans, releasing amino acid residues and deconjugated bile salts (bile acids). Can hydrolyze the amid bond in all six major human bile salts, namely glycocholate (GCA), glycodeoxycholate (GDCA), glycochenodeoxycholate (GCDCA), taurocholate (TCA), taurodeoxycholate (TDCA) and taurochenodeoxycholate (TCDCA). Shows a slight preference for glycine-conjugated bile acids as substrates. Is totally inactive toward penicillin V.
Interaction partners:
Sequence:
MCTGVRFSDDEGNTYFGRNLDWSFSYGETILVTPRGYHYDTVFGAGGKAKPNAVIGVGVVMADRPMYFDCANEHGLAIAGLNFPGYASFVHEPVEGTENVATFEFPLWVARNFDSVDEVEETLRNVTLVSQIVPGQQESLLHWFIGDGKRSIVVEQMADGMHVHHDDVDVLTNQPTFDFHMENLRNYMCVSNEMAEPTSWGKASLTAWGAGVGMHGIPGDVSSPSRFVRVAYTNAHYPQQNDEAANVSRLFHTLGSVQMVDGMAKMGDGQFERTLFTSGYSSKTNTYYMNTYDDPAIRSYAMADYDMDSSELISVAR
Protein: Uncharacterized protein (Q38BC1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MCYIILILPPWVSAPQPRHVPRVLCCICYTLLLLPRRIYVISFFLSLFCCRCVRALNMGSSGYDTSYKSSLSSAPSSVGSRTSRQISEGATSVFSGETSSVSGHDPVFRNVKRNPNLQFLKPDDSVIHVSPSARNVVRYVASNYDSFPDGHYRVVDYFRVAVEMFLQQVRLEYEKQAVQAVKNGVKKPRYTWGNKSGLAISYATSCDMLKLLYDVISEENRPKWDEVVKQFIYFLISESGIPGGVFSEQTYHTKFLDWRKGGTRYQNLSMASNVRFPSASHRRQGVENYLRSGSWLSMKTTEVTVLANTDGTSRGESMGGVTDSTPSCSNSHASSMCYPPATRIQQRINMEHPVVPAMAKQVDDFSPRRTRWREKLTQIMGSPSARGLGEDRSNMVLTFVRLCQVCDSAEQAESLTDIIVESDESIQRSFEGNGGIAVLRRFVGEPKWGCQFKFLFGLVEKLLRMRLMSWGTESRQSWLRDLNGRGRRNLDWLRNIEVIPKGEREKWTNLVRELEARYVLMPSHRDLEQPARVKRPPTGREGLEQKVASSDGHSVKPQLCVSNSRCRRLPTEFLTLPDPEAEGDVNNFMDRKAKYCEDGQAEWRKALRKAAGVDLGGVSVPIWYDPYQLLDTSQCSSA
Protein: AT11715p (Q8MR83)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSSSSTSSPTDNSSHGSVALSSALNPSLNPVSGTNTSSQKPFSLSERLNFEIYRYSSYSPNYLPENVLVDCPNDQTSRWSAYTNSPPQFLTLKLRRPAIVKKIKFGKFEKSHVCNIKKFRVYGGLDDEHMVLLLEGGLKNDNVPEVFNLRCLTEDGSENLPILYLKIVPLLSWGPSFNFSIWYVELHGQDDPMYTSARMKNYNSLREVEIIKLCLKHFRQQGYLSAFGALQEQTNVQLEHPLISELHKCLVLQGDFEKAERFIVECIDEGLMDEYLHKQDYKHSWHMKHTESDIKPGNRGGHQLVVDAKRRLIYLYGGWDGYQDLSDLWVFNIEDDQWTLLCERSELSNGPTPRSCHKMVFDPISENVFMLGRYLDNSIRTSDYIKSDFYLYDTRAGNWMQICDDTSQVGGPQLVYDHQMCMDTDKRTIYVFGGKILTPRSVNATGAIEPEYSGLFSYHIATNTWAQILVDCHHASASLADVMSIKSRITHCMVFHNKHRKLYIYGGQRGKEDLDEFLSYDVDTQAISVLNKEHPHHGTTAGNEAKFEPSSGYTLRATIDCERDEIYIFSSLSKVKDRRDIQHIDASNSFWVYSLRNHKWSRIYYCRHSGQDANSINNMNILGASKGDGTLEPCPRYAHQLVYDDVTNTHYLFGGNPGICQQQQLRLDDFWLLCLEKPKREEILKHCRFLVRKLRYEEMTRQDPLKAMQYLRHHIADVIDHSDAEQLNNFHKLASLLFKNHDGNLDRECNTPALCADADDLETDSDVSAKIKEELADGPATENLSLESNESMISSGISETASSPSSSSCTKRARADCTPELKNKRAFLFNKLVQLMPPSMVQPERNLSDFVVM
Protein: Agglutinin beta-1 chain (Jacalin beta-1 chain) (P18671)
Organism: Artocarpus integer (Jack fruit) (Artocarpus integrifolia)
Function: D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum.
Interaction partners:
Sequence:
NEQSGKSQTVIVGSWGAKVS
Protein: Tyrosine kinase-like protein (EC 2.7.10.2) (Q8IDK6)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Gametocyte-specific protein
- non-specific serine/threonine protein kinase
Sequence:
MSEHSSGVSRKLFCNSDKLFYDNFRNLDDRLNLNNNFNENRYEEIYNKKYLRNNRRFKTEPPKHLYENESEQSYSSLFHNILRSISKNIRNDEKEESSDNNNCDDDNDNNNDDDDNNNQSDSIPNNSENFNYDDNSCCEISPYDEISKKTKRVHNKIHKNEDGEYYKNVLYNNNNLSKENQINNICSSINKTQRTLKRIDTNINETLNNVKYIKMVNSDIISDVFLKNNVKSLIVYDTGGIDIELIENENPEFLYHTYTGNRISNIYYEYDDCIKNKDTYKNEEKKKKKNTFNSSLLYRENYIFKKEHELNYCYKNKDDNKKKIKNNPSEKNQIMNYSSDICSNSDSKKLFTKNKKQENVINKNIYYNNPSDYNILNNEVNYNKNTVHNTNLSKDTCEHTYKNVSNKYDIQDHNTNSSAEKYYNMNYKSSLLNKNDKYIENTSSERNKGYRSYSSMSSMLSLNAYEKENRKKYYYIGETINNIRNGWGMLIYNDRVIFEGEYKMNNAIGYFIKYNEYSTEIGYRSPISVKSVIIMSDNDNFIVQNRSENLDTSKNKEQKSGNNSWNVYKYDNDNSDHNDDSDDNGDSDDNGDSDYNNENIYNNENILNNENIYNNENILNNENILNNENILNNENIYNNENIYNNENIYNNENIHNNENIHNNENIHNNENIHNNENIHNNENIHNNENIYNHHSNDSSGENIRDSFSKNNIKNISKDTYKINNNENINNLDKNVPIYDNSSNSINNCSYYINSKYANKSSSNKGNKMISKHSTLKNSSCINNDIKNIKFSENPEENAKELKKFNNLTSYVRRNSKHKTSPARSINYLKPPVMNLIRNNIYFNRNTLGKNDKTTFCTSNIHSSNKKMREHKTTHFLSPMNIIVTSLDTDDEDNISDDNGKTDVISSCTQYEEERKKDEQNIKTEEVQYIETYMKDNDTRVLYELKINKNDDILSNHKTNESIFEKKDFKKYEEIYNNDYDHQNIIKTVCSKNDNNIDNVKNMKSVDIYDTNKKNYNRNYMNNLDNANNFDEPTNNTFEKYVKKNEGEELIFNDDQNKLHIDTFEKYKYLICENINNDKFVIKNNQITTFEKFLKNQQNFEINNKWRDTLNKIKSQNNSMRQFMQPKINNYNLCKYYVCSNNIEQIKKGALWNNTRLMGDIIKTKRENNNILNGDILNGDIINGDILNNDILNKDILNNDSLNNDSLNNDSLNNDSLNNDILNNDIPNSDVSSNVHNISSEYLNNNDKENMKFCKWGRNIFARRLRGATFPETHDDRQKHCFLFIDDYLTSNENKFDIINQNVKLRASDYNKWSVNMLYNFLKMIGLKKEAYLFKINKIRGYHILKLTDKELKKLNINNSYVRKFVLSVFRFLTNSIDNADPLSLNYNSNKKFSFNNIENICNTHITILNKIGGGSYAQVFRAKYKTIHVACKIFLYKPKDLAEESYCESYISTPRSSHRYIFPKINKNINGEDYKNTDMNNEKRKDQNIFTDNFHMDESSSMQHVPHVDDINYIEQEDNIENNTKYKNKKNNNDINNSSDTLQRNKKIKKMANLEIFRYFPTPVKYRNYEAKILYSLRECKHVIKLIGVCSLREGEESLILQHCPGGSLEKYIYKDEKKKNSPYAKSLTRPKLVKIFQQVAEGMYNIHTNQCFHRDLKLSNILLDENQNAVISDFGLSTNFSSNDSPTAYAIYGNIFYAAPEVLKGEGFFKESDVWSFAVSLWEALTKKIAYDGISASEVFCKISSGELFLPIPKDIPMELSELLKSMLEYDFTKRPLFNVIAKKLEQIRIQAEDKLHLDIMSFFDG
Protein: Ras-related protein RABA1i (AtRABA1i) (Q9S810)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Intracellular vesicle trafficking and protein transport.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN1
- Kinesin-like protein KIN-14E
- Sugar transport protein 9
- Sugar transport protein 2
Sequence:
MGAYRAEDDYDYLFKVVLTGDSGVGKSNLLSRFTRNDFSHDSRATIGVEFATRSIQCDDKIVKAQIWDTAGQERYRAITSAYYRGAVGALLVYDVTRHVTFENVERWLKELRDHTDANIVIMLVGNKADLRHLRAISTEEAKAFAERENTFFMETSALEAVNVDNAFTEVLTQIYRVVSKKALEAGDDPTTALPKGQMINVGGRDDISAVKKPGCCSA
Protein: Tetraspanin-2A (O46101)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required for assembly of smooth septate junctions (sSJs), together with Ssk and mesh. Important for barrier function of the midgut epithelium.
Subcellular location: Apicolateral cell membrane {ECO:0000269|PubMed:26848177}; Multi-pass membrane protein {ECO:0000255}. Cell junction, septate junction {ECO:0000269|PubMed:26848177}.
Interaction partners:
- Protein snakeskin
- Tetraspanin
- AT03047p
- LP01634p
- Tetraspanin
- RE03883p
- IP10114p
Sequence:
MGIGYGASDEQLEKQIGCVKYTLFCFNIVAWMISTALFALTVWLRAEPGFNDWLRILEAQSFYIGVYVLIGISIVMMAVSFLGCLSALMENTLALFVFVGTQVFGFIAIVAGSAVLLQFSTINSSLQPLLNVSLRGFVATSEYTYSNYVLTMIQENIGCCGATGPWDYLDLRQPLPSSCRDTVSGNAFFNGCVDELTWFFEGKTGWIVALAMTLGLLNVICAVMSFVLVQAVKKEEEQASNYRR
Protein: FI01544p (Rab1) (O18332)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Rab GDP dissociation inhibitor
- Trafficking protein particle complex subunit
- General vesicular transport factor p115
- Trafficking protein particle complex subunit
- Trafficking protein particle complex subunit
- Trafficking protein particle complex subunit 5
- Probable trafficking protein particle complex subunit 2
- FI18195p1
- Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
- RE60063p
Sequence:
MSSVNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDHTTAAEYAAQLGIPFLETSAKSATNVEQAFMTMAAEIKNRVGPPSSATDNASKVKIDQGRPVENTKSGCC
Protein: 30S ribosomal protein S8, putative (Q388R7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
- Uncharacterized protein
- Small ribosomal subunit protein mS41
- Enoyl-CoA hydratase/isomerase domain-containing protein
- Ribosomal protein S9
- Uncharacterized protein
- Uncharacterized protein
- Pentacotripeptide-repeat region of PRORP domain-containing protein
- Opioid growth factor receptor
- LysM domain-containing protein
Sequence:
MLRQSLLSLAKVYGAVPPLGAAQGHRLLHGKREREGSLFAVANDVKRDERLLRQQLNALLEEERMPMQARLQRSEAVSSHEAVPQTPLVDLPGVERRRDLPADPITRLFFQHKGDHALYYGTYDKPSVQDDDRVQIEKRVPRRREENLYTPIYDFCHRIREATEQRKRFVVVPSTIETRGCARVMHDHGLVAGFRDFHNDRAFAVELKYFQGDSTINVIEPCSYDGRTEFEWSPKMMRRLLNTHGIHNRLVVYICRTADNRIIDHIHAVKENIGGRGLMMVH
Protein: Calsequestrin-1 (Calmitine) (Calsequestrin, skeletal muscle isoform) (O09165)
Organism: Mus musculus (Mouse)
Function: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca(2+) ions (By similarity). Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction. Negatively regulates store-operated Ca(2+) entry (SOCE) activity (By similarity).
Subcellular location: Endoplasmic reticulum {ECO:0000250|UniProtKB:P31415}. Sarcoplasmic reticulum {ECO:0000250|UniProtKB:P31415}. Sarcoplasmic reticulum lumen {ECO:0000269|PubMed:22049211, ECO:0000269|PubMed:7945294}. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side {ECO:0000250|UniProtKB:P07221}. Mitochondrion matrix {ECO:0000269|PubMed:7945294}. Note=This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of fast skeletal muscle cells (PubMed:22049211). Preferentially forms linear and round aggregates in the endoplasmic reticulum (ER) of resting cells. In a minority of cells, homogeneously detected in the ER lumen. Colocalizes with STIM1 at endoplasmic reticulum in response to a depletion of intracellular calcium (By similarity). {ECO:0000250|UniProtKB:P31415, ECO:0000269|PubMed:22049211}.
Interaction partners:
- Triadin
- Aspartyl/asparaginyl beta-hydroxylase
- Ryanodine receptor 1
- Ryanodine receptor 2
- Ryanodine receptor 3
- Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
- Calsequestrin-2
- Sarcalumenin
- Voltage-dependent L-type calcium channel subunit alpha-1S
- Alpha-actinin-3
Sequence:
MRATDRMGARAVSELRLALLFVLVLGTPRLGVQGEDGLDFPEYDGVDRVINVNAKNYKNVFKKYEVLALLYHEPPEDDKASQRQFEMEELILELAAQVLEDKGVGFGLVDSEKDAAVAKKLGLTEEDSVYVFKGDEVIEYDGEFSADTLVEFLLDVLEDPVELIEGERELQAFENIEDEIKLIGYFKSKDSEHYKAYEDAAEEFHPYIPFFATFDSKVAKKLTLKLNEIDFYEAFMEEPMTIPDKPNSEEEIVSFVEEHRRSTLRKLKPESMYETWEDDLDGIHIVAFAEEADPDGYEFLETLKAVAQDNTENPDLSIIWIDPDDFPLLVPYWEKTFDIDLSAPQIGVVNVTDADSIWMEMDNEEDLPSADELEDWLEDVLEGEINTEDDDDDDDDDDDDDDDDD