wanglab/gogpt-training-data huggingface dataset:
Protein: CENP-meta, isoform F (EC 5.6.1.3) (M9PFL9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MSAKNASSIQVCIKVRPCEPGLTSLWQVKERRSIHLADSHAEPYVFDYVFDEGASNQEVFDRMAKHIVHACMQGFNGTIFAYGQTSSGKTYTMMGDEQNPGVMVLAAKEIFQQISSETERDFLLRVGYIEIYNEKIYDLLNKKNQDLKIHESGNGIVNVNCEECIITSEVDLLRLLCLGNKERTVGETNMNERSSRSHAIFKIIIESRKSDHSDDDAVIQSVLNLVDLAGSERADQTGARGARLKEGGHINKSLLFLSNVIKSLSENADNRFTNYRDSKLTRILQASLGGNAFTSIICTIKPSIMEESQSTLSFATRAKKIRIKPQVNEMVSDATMMKRLEREIKVLKDKLAEEERKNENQQKVEHLERQIKHDMHKIICGHSLSDKGQQKRRRTWCPTASGSHLELAETGTTEDRIDQFPKVSHLPKPVFFHTSNAGKRWDNIPKTINILGSLDIGTESNSISEEFLPAECIDFGSPRPDVLKPMLTIRQLPDLPLTPKGPLTYDALEKEVTSLRADNEAANSKISELEEKLSTLKQTMRIMEVENQVAVGLEFEFEAHKKSSKLRVDDLLSALLEKESTIESLQKSLDNLTRDVLRNSKEGHMLSIAPEQEDIAGDSICNKCEELEKLIADLESKKNSCECDQLRLEIVSVRDKLESVESAFNLASSEIIQKATDCERLSKELSTSQNAFGQLQERYDALDQQWQAQQAGITTLHEKHEHVQEKYQKLQEEYEQLESRARSASSAEFQRLQNDNTKFQADIASLNERLEEAQNMLTEVQNSESTVEKLRIQNHELTAKIKELETNFEEMQREYDCLSNQLMESVQENDALREEIKQRPTSHVEESMRSSGISSDFDEQKQDINLLHQFVQLSESVQQIELQHHSGISRLFRANQMKLDQSEPGLKLCLESAEYIEEDNRQSDATEPICLKGFLKRHRFQIKRLSQEHVDMGEEKRLLDIISQLEQEIEEKSALMEATEATINEMREQMTNLESALLEKSVIINKVEDYQRQIESLEKQNAEMTMVYEELQDRVTRESSMSESLLRVPPDEDTLPGCPTSPSRREQEVATLKTSITELQSQVSDLKAELENHLRQIQLKDGNIARLQTDFEEMSERCLSMEVRLAELDEDTKQKQELLDRQAQKLSDDLCLIDQLQKKNAQLVEQYHKATESLSLADAKPDQILLSSQYDSQIEKLNQLLNAAKDELHDVRRIKDDEISALRMEFLLQIETNEKENQAKFYAELQETKDRYESNVAELKEKLLQVEETLSSVTVRCQAELEALKSAHKENISQAVEERNNLIVQHQAEMETIRETLKNKLAEASTQQSKMEDAFRAEINEVRATLMEQLNQTKEDRDKGASKLEEVKKTLEQMINGGRVMSDTIAELEKTKAEQDLAVNKLTKDNIELEKQCSKTQEQLQMESLTRDQISFEIEAHIKKLELIVASSKKRIIELEEKCDQQVLELDKCRLEKLSLESEIQKANSEHSCTMEKLQELQAEMKVLSNRNEKEKCDFETKLETFTFKITDLEEVLKEAQHKVILYDDLVSQHERLKICLAEANELSSNLQKKVMSLHTELIDSQKGISSRDVEINELREELKAAMDAKATASAEQMTLVTQLKDVEERMANQAEKFTREAANLKGSINELLLKLNSMQETKDMLESGNEELKEQLRNSQNLRNMLDEESKMCISLKEKLVKLEDAKTSLEQQLRDNKSEIYQRHTELTKEVELGRNRIGELTKKCEELCSDLENSDQIRLDLQETKEQLKKTLENNLGWQQKVDEVTRECEKLRFDMQSKEVQNESKVQELISECEELRSTLKSKEASFQSEKESMDRTISSLLEDKRNLEEKLCSANDIVAKLETEIAALRPRKSLDRNPVPRKSITFESEIRKNRRISVHDERRQSYWNDVREFGIMTDPVDNNCNCAELNSKLQDCQRELFIRESQVTALKMELDHHPLKDENAQLTKRVIEEQDKAKVEQKRLKMKLQDLNARINDLTTASAKEPESNQMAQAAKPATVAAQTQTESDLETILEKTNVKYQEAVRMLRYRYHLIQELKEKLRQNENSDTSNITSLSAGQTSALKCESQKKEILAIKYKYEAAKRILAIRNDDLDALREKLAKYETTTSDK
Protein: Amyloid beta precursor protein binding family B member 1 (V9GY97)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQEESQLTWTGFAHGEGFEDGEFWKDEPSDEAPMELGLKEPEEGTLTFPAQSLSPEPLPQEEEKLPPRNTNPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMSGGWGEGKDLLLQLEDETLKLVEPQSQALLHAQPIISIRVWGVGRDSGRDFAYVARDKLTQMLKCHVFRCEAPAKNIATSLHEICSKIMAERRNARCLVNGLSLDHSK
Protein: Sodium/glucose cotransporter 2 (Na(+)/glucose cotransporter 2) (Low affinity sodium-glucose cotransporter) (Solute carrier family 5 member 2) (P31639)
Organism: Homo sapiens (Human)
Function: Electrogenic Na(+)-coupled sugar simporter that actively transports D-glucose at the plasma membrane, with a Na(+) to sugar coupling ratio of 1:1. Transporter activity is driven by a transmembrane Na(+) electrochemical gradient set by the Na(+)/K(+) pump. Has a primary role in D-glucose reabsorption from glomerular filtrate across the brush border of the early proximal tubules of the kidney (By similarity).
Subcellular location: Apical cell membrane {ECO:0000305|PubMed:34880493, ECO:0000305|PubMed:37217492, ECO:0000305|PubMed:38057552}; Multi-pass membrane protein {ECO:0000269|PubMed:34880493, ECO:0000269|PubMed:37217492, ECO:0000269|PubMed:38057552}.
Interaction partners:
- PDZK1-interacting protein 1
- Dipeptidyl peptidase 4
- Glucagon-like peptide 1 receptor
- Adenylate cyclase type 7
- Insulin
- Pro-glucagon
- Sodium-dependent noradrenaline transporter
- Solute carrier family 2, facilitated glucose transporter member 2
- Sucrase-isomaltase, intestinal
- Renin
Sequence:
MEEHTEAGSAPEMGAQKALIDNPADILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGRSMVWWPVGASLFASNIGSGHFVGLAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQYLRKRFGGRRIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALMYTDTVQTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSLTVSEDPAVGNISSFCYRPRPDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKSLTHIKAGCILCGYLKLTPMFLMVMPGMISRILYPDEVACVVPEVCRRVCGTEVGCSNIAYPRLVVKLMPNGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGRLWVVFIVVVSVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFWGLIGGLLMGLARLIPEFSFGSGSCVQPSACPAFLCGVHYLYFAIVLFFCSGLLTLTVSLCTAPIPRKHLHRLVFSLRHSKEEREDLDADEQQGSSLPVQNGCPESAMEMNEPQAPAPSLFRQCLLWFCGMSRGGVGSPPPLTQEEAAAAARRLEDISEDPSWARVVNLNALLMMAVAVFLWGFYA
Protein: Sodium/potassium-transporting ATPase subunit beta-1-interacting protein (Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein) (dNKAIN) (A6MHQ4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Induces a small but significant sodium conductance when expressed in Xenopus oocytes.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MGSCSCTRRHFLLSICFLQVITIIERQVFDFLGYMWAPILVNFFHILFIIFGFYGAYHFRVKYIITYLIWNFLWIGWNTFLICFYLNVGQLNRDSDLLNLGTGSVSWFEANGYGCKPTYNMAADDTFRPQRPERVEGCLLDYPLVEITHSGVQCALALLGILGAILISCIFLDEDDRFDFMNGDAKSPQHTVVHPMYVSYTSIPTTSASATMQSNKHLQLQHQQPQQNSLKLYHHQQQQQPKLHHFNKNYQLSGSNNNTLNNNLHQRAPALLPPNTTNNRSASFQTQSHPSNNHVTQRTGGEGSNCSSLRRHRQHHSKALVSPSPMSPQTTPSLSYASLQNSSPYLAGNSLSNSNYSIFQSPDSLQGSSHFARIHHKPKPPKSDYPVSGEFNPGGNISSPVRPLDRLSRSLEDDEDNFSLQKFAPGEHGVTYVPFQSPTPNSLFLGENNNSQPHLVFHTNSRSSPNNNAYPYDQSGLPSSLRMGSNSNARRPTHIPLPTVPMHNCQEVENDEDADGESEQDHDQMLTPPPPPLVRPHIHQRLGQAPYLDLSPEVAERYAIPSKLGPSLPIQVPLPVPHGSPMVRRSNRRPRPSNPVNFCDQIRATPPGYVVRAQSDDRLMEQVEADAAPHVNRRSGRGGSGQKTRPRSFCNSIVGVQG
Protein: PapD-like superfamily protein (F4JJI7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MTMTEEKPTSDGKGGWGFFKIPFRNSSGHRNAASSAATSPFPSGASSSSTSSHLHNHHQHHHQHHHQHHHQLGYNGPHGDGSGQNQHPTPSPSVSSVAKSFLPTKRRLKLDPSEKLYFPWFVSEDLRSIDTSLKFLSFNEPGKQVRSAIKIKNTSKSHVAFKFQTTAPKSCFMRPPGAILAPGETIIATVFKFVEPPENNEKPMDQRSRVKFKIMSLKVKGPMDYVPELFDEQKDDVSKEQILRVIFLDPERSNPALEKLKRQLAEADAAVEARKKPPEETGPKMIGEGLVIDEWKERRERYLAQQQGEGADSV
Protein: Myosin regulatory light polypeptide 9 (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9) (Q5E9E2)
Organism: Bos taurus (Bovine)
Function: Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity). In myoblasts, may regulate PIEZO1-dependent cortical actomyosin assembly involved in myotube formation (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9CQ19}. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q9CQ19}. Note=Colocalizes with F-actin, MYH9 and PIEZO1 at the actomyosin cortex in myoblasts. {ECO:0000250|UniProtKB:Q9CQ19}.
Interaction partners:
- Myosin-10
- Myosin-9
- Myosin light chain kinase, smooth muscle
- Myosin-11
- Myosin light polypeptide 6
- Myosin light chain 6B
- Myosin light chain kinase 3
- Myosin light chain kinase 2, skeletal/cardiac muscle
- Rho-associated protein kinase 2
- Serine/threonine-protein phosphatase PP1-beta catalytic subunit
Sequence:
MSSKRAKTKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD
Protein: Solanesyl-diphosphate synthase 1, mitochondrial (OsSPS1) (EC 2.5.1.84) (All-trans-nonaprenyl-diphosphate synthase 1 (geranyl-diphosphate specific)) (Q653T6)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Involved in the supply of solanesyl diphosphate for ubiquinone-9 (UQ-9) biosynthesis in mitochondria. Farnesyl diphosphate is the preferred substrate.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:20421194}.
Interaction partners:
- Diphosphomevalonate decarboxylase
- Farnesyl diphosphate synthase)
- Os05g0543400 protein
- 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, chloroplastic
- isopentenyl-diphosphate Delta-isomerase
- isopentenyl-diphosphate Delta-isomerase
- Solanesyl-diphosphate synthase 2, chloroplastic
- Probable solanesyl-diphosphate synthase 3, chloroplastic
- Os04g0657100 protein
- Isopentenyl phosphate kinase
Sequence:
MSWRWALARRVAALGATSGGGDGATAQAQRLFSSAAALLGRHPPPPSPPHYQIRSKVVGCRGATFVSSRWLHDAQYQVRQDGLSRSEEQQDPFELVADELSLLANRLRSMVAAEVPKLASAAEYFFKVGAEGKRFRPTVLLLMASALKFPLSDSTEVGVLTILANKLRTRQQNIAEITEMIHVASLLHDDVLDDADTRRGVSSLNCIMGNKLSVLAGDFLLSRACVALAALGNTEVVSLMATAVEHLVTGETMQISTSREQRRSMDYYLQKTYYKTASLISNSCKAVAILAGHTADVSMLAYEYGRNLGLAFQLIDDVLDFTGTSASLGKGSLTDIRHGIITAPMLYAMEEFPQLHEVVDRGFDNPANVELALDYLQKSRGIEKTKELAREHANRAIKAIEALPDSDDEDVLTSRRALIDITERVITRTK
Protein: Tubulin alpha-3 chain (EC 3.6.5.-) (P06605)
Organism: Drosophila melanogaster (Fruit fly)
Function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
Subcellular location: Cytoplasm, cytoskeleton.
Interaction partners:
- Tubulin beta-2 chain
- Tubulin beta chain
- Tubulin beta-3 chain
- beta-Tubulin at 65B
- Tubulin alpha-1 chain
- Serine/threonine-protein kinase CG17528
- non-specific serine/threonine protein kinase
- Tubulin beta chain
- Echinoderm microtubule-associated protein-like CG42247
- Protein mini spindles
Sequence:
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTVGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAVYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPVISAEKAYHEQLSVAEITNACFEPANQMVKVDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGMDSGDGEGEGAEEY
Protein: Small ribosomal subunit protein mS41 (Function required for yeast viability protein 4) (Protein FYV4, mitochondrial) (P38783)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane. mS41 is involved in telomere length regulation and required for survival upon exposure to K1 killer toxin.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095}. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1. {ECO:0000269|PubMed:25609543}.
Interaction partners:
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein mS43
- Small ribosomal subunit protein mS47
- Small ribosomal subunit protein mS27
- Small ribosomal subunit protein mS37
- Small ribosomal subunit protein uS2m
- Small ribosomal subunit protein mS23
- Small ribosomal subunit protein mS42
- Small ribosomal subunit protein bS21m
- Small ribosomal subunit protein bS1m
Sequence:
MIPSRISHKFPLFLRSSLAAPKAAYRFSSTIPKPSDQVPDVDAFLNKIGRNCNELKDTFENNWNNLFQWDSKILKEKGVNIQQRKYILKQVHNYRNNRPIHEIKLGKKSFFGGERKRKAFTAKWKAENKQ
Protein: Fucose-1-phosphate guanylyltransferase (EC 2.7.7.30) (GDP-L-fucose diphosphorylase) (GDP-L-fucose pyrophosphorylase) (G5E8F4)
Organism: Mus musculus (Mouse)
Function: Catalyzes the formation of GDP-L-fucose from GTP and L-fucose-1-phosphate. Functions as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids (Probable).
Subcellular location: Cytoplasm {ECO:0000305|PubMed:14686921}.
Interaction partners:
- GDP-L-fucose synthase
- L-fucose kinase
- Serine/threonine-protein kinase TNNI3K
- GDP-mannose 4,6 dehydratase
- Leucine-rich repeat and IQ domain-containing protein 3
Sequence:
MASLREATLRKLRRFSELRGKPVAAGEFWDVVAITAADEKQELAYKQQLSEKLKKRELPLGVQYHVFPDPAGTKIGNGGSTLCSLECLESLCGDKWNSLKVLLIHSGGYSQRLPNASALGKIFTALPLGEPIYQMLELKLAMYVDFPSNMRPGVLVTCADDIELYSVGDSEYIAFDQPGFTALAHPSSLAVGTTHGVFVLHSDSSLQHGDLEYRQCYQFLHKPTIENMHRFNAVHRQRSFGQQNLSGGDTDCLPLHTEYVYTDSLFYMDHKSAKKLLDFYKSEGPLNCEIDAYGDFLQALGPGATAEYTRNTSHVTKEESQLLDMRQKIFHLLKGTPLNVVVLNNSRFYHIGTLQEYLLHFTSDSALKTELGLQSIAFSVSPSVPERSSGTACVIHSIVDSGCCVAPGSVVEYSRLGPEVSIGENCIISSSVIAKTVVPAYSFLCSLSVKINGHLKYSTMVFGMQDNLKNSVKTLEDIKALQFFGVCFLSCLDIWNLKATEKLFSGNKMNLSLWTACIFPVCSSLSESATASLGMLSAVRNHSPFNLSDFNLLSIQEMLVYKDVQDMLAYREHIFLEISSNKNQSDLEKS
Protein: Gll0198 protein (Q7NP59)
Organism: Gloeobacter violaceus (strain ATCC 29082 / PCC 7421)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Integrase/recombinase
- Xer protein
Sequence:
MLMTVFSSAPELALLGSTFAQVDPSNLSVSDSLTYGQFNLVYNAFSFAIAAMFASALFFFSAQALVGQRYRLALLVSAIVVSIAGYHYFRIFNSWDAAYVLENGVYSLTSEKFNDAYRYVDWLLTVPLLLVETVAVLTLPAKEARPLLIKLTVASVLMIATGYPGEISDDITTRIIWGTVSTIPFAYILYVLWVELSRSLVRQPAAVQTLVRNMRWLLLLSWGVYPIAYLLPMLGVSGTSAAVGVQVGYTIADVLAKPVFGLLVFAIALVKTKADQESSEPHAAIGAAANKSGGSLIS
Protein: Retromer subunit (A0A1D8PJS7)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Vacuolar protein sorting-associated protein 29
- Vacuolar protein sorting-associated protein 35
- Sorting nexin-3
- Sorting nexin 1
- Vacuolar protein sorting-associated protein 17
- Type I sorting receptor
- Oxidant-induced cell-cycle arrest protein 5
Sequence:
MSIFFKAPLDIEIRLDNEDTRKHVEVKTPQGRVEKLPIYKDGESVKGVVTLRTKEGRKLEHLGVRVQLLGSIETNTDGISSSEFLTLATELAAPAQLSHPESYPFEFKNVEKQYESYRGKNVRLRYYIKVTVLRKSSSEIIREKELWVYHYTTAVPKPVTGLSSSSTADSKLGAKKANEDTLQKPATPSSNDDASANTSKGSTISKRNESHSVKMDVGIENCLHIEFEYSRSRFSLTDAIIGKIYFLLVRLKIKHMELSLIRRETVGAPPNQVTDSETVVRFEIMDGAPVKGETIPIRLFLSGFDLVPTYRDVNKKFSTRTYLSLVLIDEDARRYFKQSEIILYRDQ
Protein: Protein kinase, putative (Q586Q3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Cell division control protein, putative
- Cell-division control protein 2 homolog 6, putative
- cyclin-dependent kinase
- cyclin-dependent kinase
- cyclin-dependent kinase
- Protein kinase, putative
- Protein kinase, putative
Sequence:
MAELLRKKIEALKSRKAAAEEPVVTPQSSSTTAALAPSSSLPSPSTTVTAAAPAQVKSTCSVPLANLPPAFVSPYTAVVKYRDTVKDPLCAQFTTSVAVELFKTFIQQRHRGNVSVQAQKRARSEDFGATERPVRSKEDNDSAKNEEEVQQQREEGYQHQHHNNSSGEGESLSGVGSGGDGINKNIVHFTHPPLCTVVSYFLPYLEARCFTHSDVKDREGKTTWASEAPDAPSLLQGYVTSLHKNVKSSVKAIRVSGKTRPPCRSVNEYVPVGQIAHGVYGVVYRATEANGSSSSGGGRGRKFALKQVKQRWLEESEVGFPPYLLREFDLLLRLRHPNIVCGREVVLLDKKSNSSKASKQQEVKPATGTTGREVSNEVGRHNHRTDNVQKTNEEPTASGNDDGLPSSCNQGGDKKEEEPPQIKTKLSADKMKDVYLVMEYCPYDLKAFIYHRKGVAALLHLSSANKHPDAPRCFLSRVKCVMQQLFTGVAFLHDHRILHRDIKTSNILISSTGEVKLCDFGLGRHYREGQELTANVVTLMYRAPELHFGITDYSYKMDMWSLGCIMAEIFLKEPLFRAEEESRHFAVICDVIGIPTEETFSGLYKMHEVTRLMRSLKRYNRENTLQQIFSRSNHSGAATLPPSGMDLLNRILRWNPIDRLSAREALEHKFFHEDPLPCMPEELLAPLPTTVAAEQMVGVPSQREGGAAVVAGKSSSETNCAIPQALESCEGGDNEETCGFGETVRSNAESPTADVLRARASNIDEEVEVEVRRR
Protein: 14-3-3-like protein GF14-C (G-box factor 14-3-3 homolog C) (Q6ZKC0)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes.
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- Protein HEADING DATE 3A
- HECT-type E3 ubiquitin transferase
- Os03g0311300 protein
- Os12g0463700 protein
- Arsenate reductase 2.2
- F-box domain containing protein, expressed
- Arsenate reductase 2.1
- F-box domain containing protein
- Os05g0483801 protein
Sequence:
MSREENVYMAKLAEQAERYEEMVEYMEKVAKTVDVEELTVEERNLLSVAYKNVIGARRASWRIVSSIEQKEEGRGNEEHVTLIKEYRGKIEAELSKICDGILKLLDSHLVPSSTAAESKVFYLKMKGDYHRYLAEFKTGAERKEAAESTMVAYKAAQDIALADLAPTHPIRLGLALNFSVFYYEILNSPDKACNLAKQAFDEAISELDTLGEESYKDSTLIMQLLRDNLTLWTSDLTEDGGDEVKEASKGDACEGQ
Protein: Voltage-gated potassium channel regulatory subunit KCNG1 (Potassium voltage-gated channel subfamily G member 1) (Voltage-gated potassium channel subunit Kv6.1) (kH2) (Q9UIX4)
Organism: Homo sapiens (Human)
Function: Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q14721}; Multi-pass membrane protein {ECO:0000305}. Note=Colocalizes with KCNB1 at the plasma membrane. {ECO:0000250|UniProtKB:Q14721}.
Interaction partners:
- Ubiquitin-like protein FUBI
- Heterogeneous nuclear ribonucleoprotein K
- Fragile X messenger ribonucleoprotein 1
- RNA-binding protein FXR2
- Poly
- RNA-binding protein FXR1
- Poly
- Voltage-gated potassium channel subunit beta-3
- Small ribosomal subunit protein uS13
- Vitamin K-dependent gamma-carboxylase
Sequence:
MTLLPGDNSDYDYSALSCTSDASFHPAFLPQRQAIKGAFYRRAQRLRPQDEPRQGCQPEDRRRRIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVEREEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVMFRRAQFLIKTKSQLSVSQDSDILFGSASSDTRDNN
Protein: 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase (EC 4.1.2.55) (F9VPG1)
Organism: Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii)
Function: Involved in the degradation of glucose and galactose via the Entner-Doudoroff pathway. Catalyzes the reversible cleavage of 2-keto-3-deoxy-6-phosphogluconate (KDPG) and 2-keto-3-deoxygluconate (KDG) forming pyruvate and glyceraldehyde 3-phosphate or glyceraldehyde, respectively. It is also able to catalyze the reversible cleavage of 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) and 2-keto-3-deoxygalactonate (KDGal).
Interaction partners:
- 2-dehydro-3-deoxygluconokinase
- Non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase
- gluconate dehydratase
- gluconate dehydratase
- Indolepyruvate--methylviologen oxidoreductase subunit a
- Indolepyruvate--methylviologen oxidoreductase subunit b
- Indolepyruvate--methylviologen oxidoreductase subunit c
- Phosphoglucosamine/phosphogalactosamine mutase
- Triosephosphate isomerase
- Pyruvate kinase
Sequence:
MDIVTPILTPFTKEGKIDVEKLKAHAKFLIDNGIDLLFVNGTTGLGPALSKEEKLTTLKTIYDVTNKVIFQVGSLNINDVIDLVKASKDFDIVGIASYPPFYFPRLPEKFLLKYFTTIANYSPHSLYIYNYPLATGYDISAKIVYQMKDLITGLKDTNQDLSHSLEYKILMPNLKVYNGSDSLVFYSLTSLDGSVTAASNYLPHVMKKMKEHITSGQVSKAIELQKLINKALDISRKYGQLSAIYYLVKEFLGYDVGYPRGPIFPLEEDEVKALLSEIQPVKKEIERAVS
Protein: E3 ubiquitin-protein ligase sina (EC 2.3.2.27) (RING-type E3 ubiquitin transferase sina) (Seven in absentia protein) (P21461)
Organism: Drosophila melanogaster (Fruit fly)
Function: E3 ubiquitin-protein ligase that is required for specification of R7 photoreceptor cell fate in the eye by mediating the ubiquitination and subsequent proteasomal degradation of Tramtrack (ttk). E3 Ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Acts via the formation of a complex with ebi and phyl that ubiquitinates the transcription repressor ttk, a general inhibitor of photoreceptor differentiation, in a subset of photoreceptor cells in the eye, leading to the differentiation of cells into neurons. Also involved in external sensory organ development.
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- GEO06356p1
- BIP1 protein
- Protein tramtrack, alpha isoform
- AT16033p
- Protein phyllopod
- Calcyclin-binding protein
- Ubiquitin-conjugating enzyme E2-17 kDa
- F-box-like/WD repeat-containing protein ebi
- Armadillo segment polarity protein
- Ubiquitin carboxyl-terminal hydrolase
Sequence:
MSNKINPKRREPTAAAAGAGATGVATNTSTSTGSSSAGNTSSANTSSSSSSSLSSAGGGDAGMSADLTSLFECPVCFDYVLPPILQCSSGHLVCVSCRSKLTCCPTCRGPLANIRNLAMEKVASNVKFPCKHSGYGCTASLVYTEKTEHEETCECRPYLCPCPGASCKWQGPLDLVMQHLMMSHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGHHFMLVLEKQEKYDGHQQFFAIVQLIGSRKEAENFVYRLELNGNRRRLTWEAMPRSIHEGVASAIHNSDCLVFDTSIAQLFADNGNLGINVTISLV
Protein: Bardet-Biedl syndrome 1 (Bbs1 protein) (A4QP86)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSSVPQELKDTSVASSKWLDAHYDPVANLYTFSSCIALSDLHGDGENKLVVGDLGTGLCNMKLKVYRGTGLLSESTLLDLPTGLVSFLMDLHEPRTPAIAVASGPFIYVYKNMRPYFKFTLPSLDINPLEQDVWCQAKEDMIDPMTLKEMLEGLRDKSEIPLSVRSLRFLMLEPHEMENFVHLHKELPIRRQTVITCIGTLKKNMADEDAVSCLVIGTENGDVYILDPEAFTILYKMSLPSTPTLMDVTGQFDVEFRITVACRNGNIYILRRDSPKPKYCIELSSHPVGLVRMGKNVVVGCTHETLHGYTQKGKKLWTAYLPAPVTTMALMDLPTRGFQAVLVGLANCEVHMYRDKNLIGTIKTPDVVTSICFGRYGREDGTLIMTTKGGGLIVKILKRTAVFDDRDSTPGPPIAQSIRLNVPKKTKLYVDQTLRERENAIAMHRAFQMDLSRLRLAAARAYVKALESSLTPMSASLTEPLKMNAVVQGLGPSFKLTLNIQNTAASRPVMNLAISFLYDESLYSMRTAFFKIPLLVPGLNYPIDTFVECLSDKGVSDIIKVFVLREGKSAPLLTAHINMPVSEGLALN
Protein: F-actin-capping protein subunit alpha (Q9W2N0)
Organism: Drosophila melanogaster (Fruit fly)
Function: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:A0PFK5}.
Interaction partners:
- F-actin-capping protein subunit beta
- Dynactin subunit 2
- Leucine-rich repeat, isoform F
- Actin-related protein 10, isoform A
- Actin-related protein 1
- Dynactin subunit 4
- CIN85 and CD2AP related, isoform J
- Adenylyl cyclase-associated protein
- 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial
- WASH complex subunit 4
Sequence:
MEQTPITDAEKVRIVSDFILHAPPGEFNEVFNDVRELLKNDTLLKDGASHAFAQYNKDQLTPVRIEGTDHNAIISEHNDLGNGRFYDPRTKQAFKYDHLRKEASDYQDVEADATAEPWRAALDLETLAYTASHYRHGVSSVFGKAQGNQITLTICIEDHQFQPKNYWNGRWRSQWHVTFQAGSGTAELKGVLKVQVHYYEDGNVQLVSSKECRESVVVSNEQQVAKEVIRLIEDAENEYQLAISENYQTMSDTTFKAMRRQLPITRTKIDWSKIVSYSIGKELKTQ
Protein: Fast skeletal muscle troponin T (Fast troponin T isoform a) (Troponin T type 3A (skeletal, fast)) (Troponin T3a, skeletal, fast) (Q9I8U9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Troponin C, skeletal muscle
- Fast muscle troponin I, tandem duplicate 4)
- Troponin C, slow skeletal and cardiac muscles
- Fast skeletal muscle myosin light polypeptide 3
- Troponin I type 1b
- Myosin, light chain 1, alkali; skeletal, fast
- Myosin regulatory light chain 2, skeletal muscle isoform A
- Troponin I type 2b
- Troponin C, slow skeletal and cardiac muscles
- Troponin I type 1a
Sequence:
MSDTEDIEQHFEEEKPKFKPTAPKIPDGEKVDFDDIQKKRHNKDTLELQCLIDAHFEHRQKEEEELIALRERIEKRRSERAEQQRIRTEQEKERHARREEERLRKEEADAKKKAEEDAKKKSALSSMGSNYSSYLQKADSKKGGKKQTEREKKKKILAERRKQLNIDHLNEDKLRDKAQELYEWIKTLESEKFEHMERLKRQKYEVTTLRRRVEELSKFSKKGAAARRRK
Protein: LIM domain-containing protein D (Q9BIW4)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Binds to F-actin and may modulate the chemotactic response during early development and contribute to the maintenance of the strength of the actin cytoskeleton.
Subcellular location: Cell projection, pseudopodium {ECO:0000269|PubMed:12374734}. Cytoplasm, cell cortex {ECO:0000269|PubMed:12374734}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12374734}.
Interaction partners:
- Paxillin-B
- SAP DNA-binding domain-containing protein
- Calponin-homology
- Ankyrin repeat-containing protein
- Phospholipase D B
- LIM domain-containing protein C
- Uncharacterized protein
- Calcium-regulated actin-bundling protein
- LMBR1 domain-containing protein 2 homolog B
Sequence:
MSNLGKCTRCQKTVYSQEGFIAVKVPFHRSCFKCEVCNWQLVLTNYKSINGKVYCANHYPVGGLSVTPEKTHTTSDDLVMKNALNAPRVETVNEQLRGGNEKPQTSTDDLVTKNALNAPKSNLVNNQVRGTSDSAPLTSADDLVTRNALKAPKSDLVNNQVRGTSEMGPQAGIDIVTANALKAPKLETMSGYQKSVQN