wanglab/gogpt-training-data huggingface dataset:
Protein: Ephrin receptor 1 (EC 2.7.10.1) (Tyrosine-protein kinase Eph receptor) (Variable abnormal protein 1) (O61460)
Organism: Caenorhabditis elegans
Function: Receptor for members of the ephrin family (By similarity). Receptor for major sperm proteins (MSPs), that functions as sperm-sensing checkpoint which inhibits oocyte meiotic maturation and ovulation when sperm are not available for fertilization. Specifically, functions to negatively regulates oocyte maturation and MAPK activation in the absence of MSPs. Required for the MSP-mediated increase in the basal sheath cell contraction rate in somatic cells. Phosphorylates phosphatase daf-18/PTEN which probably promotes daf-18 degradation. By inactivating daf-18, regulates positively insulin-like daf-2 signaling cascade. Involved in interactions between neuronal substrate cells and a migrating epithelial sheet in head epidermis morphogenesis. Also required for cell movements following gastrulation and during ventral closure of the epidermis. Might play a role in spermatheca morphogenesis. Involved in axon guidance of SDQL neurons during neurogenesis.
Subcellular location: Cell membrane {ECO:0000269|PubMed:12533508, ECO:0000269|PubMed:19853560}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Ephrin RBD domain-containing protein
- Ephrin RBD domain-containing protein
- Ephrin RBD domain-containing protein
- Ephrin-4
- Protein sax-3
- Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18
- Major sperm protein
- Netrin unc-6
- PID domain-containing protein
- Semaphorin-2A
Sequence:
MRLYNSRILNPHQSIFILVLQCLITIVTSHQEVLFDLSKVGSDLKWDQVSLRHDRDDVWMEETWRNPAATDEKHANQRAYVTCNYDMINPSNWLFSHFIEVKTARRIYIELLFNTRDCDAYLNPKSCKETFSVYLKQFKTSRPGSTKIEKERFSEDIDNWKNIGRLARSNSNMTTETLGMEIDSDTKTIRIAFEEQGICLSLLNVKIYYRICDEFTDQLVYFRPQVTGPKETDMVRMNGSCIPNASKKIPGVDLIGLCMSTGSGIKTSGECVCDSGYSQIADSNGARCESCPTNTYKPKGQSLCKSCPSNSISSEAASSCRCLNGYFRAEDELISMPCTQPPSRPIKLVANAITATSTRLSWNEPSSLGGRPEIWYEVKCSGRGECGTVVMTPGDKKLSTRSVQINGLRPSSDYTFLVFAKNKVSAQFPEFSEKNAVIDIRTRSEEEDVPPVSHLRVDASQSDGITIAWSVSDSDVSDFEVEVRPAIVKKRTFETRHVNMTYTTFIGLNPETVYQFRVRIRDDLRWSQPISYQLGRGLMSSPSSNEVEESQFLNQTGSALLIIIALILIVIAVALCMIVVQKKSKNRKQMSDLDVLDTYKQDSMTPDYHTTSRHHHHQGNLPATLHEQLRSTTKLNAPLIPSFGSPISQPPPYYGGVHPNSGKYKTYVDPTTYEDPYQALIEFTFDISPNDVFITQVIGGGEFGDVCLGGLSKNSPAAAKWSVSNTTMGRGGGGGGYESEPYETVAIKTLKSGSSAKAKAEFLTEATIMGQFSHPNVIRLIGVVTSAEPVMIVAEYMANGSLDQFLRNTDQRGEKVHWEKITEMLYGIASGMKYLTDMGYVHRVSFLRDLAARNVLLDMELRCKIADFGLSRGVRSEGSSVEPEYTTNGGKIPVRWTAPEAITHRKFTPSSDVWSFGVVIWEVCSFGERPYWDWTNQKVISEVMIGYRLPPPMDCPMGLYRIAQWCWKMERHERPTFTQLLATFHKYILQPTLIEHDPGELPRRVQSQSALNTYGSVNVGVVPTPPSSAAPMPSLDDFLRQIGLNHVYGQLVSNNIHSVSDLANTSHLDLLAYGLMSAECSTVRDGLNGRISGSPPGSSGTIHATTRGTRTTRPPREEGFFV
Protein: J domain-containing protein (Q9TZK8)
Organism: Caenorhabditis elegans
Interaction partners:
- Guanyl-specific ribonuclease pgl-1
- Serine/threonine protein phosphatase 2A regulatory subunit
- Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1
- Protein meg-2
- Protein meg-1
- Guanyl-specific ribonuclease pgl-3
- NFX1-type zinc finger-containing protein 1 homolog
- F-box domain-containing protein
- MUTator
- ATP-dependent RNA helicase glh-4
Sequence:
MSSSKLSSCDLPNSRGNREGHRSHSRSNLESASKNMGHHISIEELFYSFVKQDGVQSTSRGYGGRSHHGSVSFNGNPSMNGDQLNHSINQSMNAARANRNVFNSSSIPPTAPVFSADFRQNSQTRNNSSWNQRNLSVSTYQYNTQQSNTGHSRSRPNGQLGRSFSDGSNNHGHAGNVSFSGSSVPAGFQKQETKAYQQLHGNKSFNAQAGVQAPGDHKDKRYGGMFGNELINSINSSFGQQHDVFKPRNLNQSFSGFTINEALTRKHHQEGSRNDRRRSHGSTNVQDRAFYNTDDNELSDDVFIEDSNGVANGPKSVTNKSQQQSRGTKDAGSQVAEKLNSSRGAAQRNLKSNVFSKDGTELSVEQLLEIVSMKIGQHLHSASSSHGECSNLNRTLPARSDLNCSIGEDFDSSFLDVNNRTLPENLSKKTSVQKHRRGSSRSASRLASLDVTLETVEEDVEPTPSPHPSSPPKISRRKWTGTFDANVEEMRRLLHGDPGKPKSTKRAFSSKDQRTPSLSIITSPKALIGEKCLTASNKSSKIDKSLGMIDSKLTKSPMYSATVSGKEATSGNRIARKLTPGLDGLKSSHCTGNPVSIDCNGCPTPKRSGINCDNRMAEVNNQAGRWSSEATSQPAPLPCKSANPTEDSSQDAPPTSPPPRISDSLTAFLEAQQDFNDYIDAHYKEKTQLLKVNLNIHGMSPERWLYLNYFCTETIPRLDGPYADDPRVPPVRNIFRRWFLRFAEACLGNPNDLAVQKDIALEFVQARLDDTSSSTDSTNMLYMLWKECIGQKNIISIADACLLVYLRKSDPVRYLNAKREWLESIFDPPRDQ
Protein: Cytochrome P450 like protein (Cytochrome P450, family 77, subfamily B, polypeptide 1) (F25C20.25 protein) (Putative cytochrome P450) (Q9SAB7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein HOTHEAD
- Cytochrome P450 704B1
- Fatty alcohol:caffeoyl-CoA acyltransferase
- Omega-hydroxypalmitate O-feruloyl transferase
- F21B7.2
- ABC transporter B family member 1
- Auxin transporter protein 1
- ABC transporter B family member 19
- Cytochrome P450 86B1
- Cytochrome P450 86A4
Sequence:
MDLTDVIIFLFALYFINLWWRRYFSAGSSQCSLNIPPGPKGWPLVGNLLQVIFQRRHFVFLMRDLRKKYGPIFTMQMGQRTMIIITDEKLIHEALVQRGPTFASRPPDSPIRLMFSVGKCAINSAEYGSLWRTLRRNFVTELVTAPRVKQCSWIRSWAMQNHMKRIKTENVEKGFVEVMSQCRLTICSILICLCFGAKISEEKIKNIENVLKDVMLITSPTLPDFLPVFTPLFRRQVREARELRKTQLECLVPLIRNRRKFVDAKENPNEEMVSPIGAAYVDSLFRLNLIERGGELGDEEIVTLCSEIVSAGTDTSATTLEWALFHLVTDQNIQEKLYEEVVGVVGKNGVVEEDDVAKMPYLEAIVKETLRRHPPGHFLLSHAAVKDTELGGYDIPAGAYVEIYTAWVTENPDIWSDPGKFRPERFLTGGDGVDADWTGTRGVTMLPFGAGRRICPAWSLGILHINLMLARMIHSFKWIPVPDSPPDPTETYAFTVVMKNSLKAQIRSRT
Protein: Alkanal monooxygenase beta chain (EC 1.14.14.3) (Bacterial luciferase beta chain) (P19908)
Organism: Aliivibrio fischeri (Vibrio fischeri)
Function: Light-emitting reaction in luminous bacteria. The specific role of the beta subunit is unknown, but it is absolutely required for bioluminescence activity.
Interaction partners:
Sequence:
MKFGLFFLNFQKDGITSEETLDNMVKTVTLIDSTKYHFNTAFVNEHHFSKNGIVGAPITAAGFLLGLTNKLHIGSLNQVITTHHPVRVAEEASLLDQMSEGRFILGFSDCESDFEMEFFRRHISSRQQQFEACYEIINDALTTGYCHPQNDFYDFPKVSINPHCYSENGPKQYVSATSKEVVMWAAKKALPLTFKWEDNLETKERYAILYNKTAQQYGIDISDVDHQLTVIANLNADRSTAQEEVREYLKDYITETYPQMDRDEKINCIIEENAVGSHDDYYESTKLAVEKTGSKNILLSFESMSDIKDVKDIIDMLNQKIEMNLP
Protein: Carbohydrate sulfotransferase 11 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 1) (Chondroitin 4-sulfotransferase 1) (C4S-1) (C4ST-1) (C4ST1) (Q9NPF2)
Organism: Homo sapiens (Human)
Function: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Interaction partners:
- Carbohydrate sulfotransferase 12
- Carbohydrate sulfotransferase 13
- Carbohydrate sulfotransferase 3
- Carbohydrate sulfotransferase 15
Sequence:
MKPALLEVMRMNRICRMVLATCLGSFILVIFYFQSMLHPVMRRNPFGVDICCRKGSRSPLQELYNPIQLELSNTAVLHQMRRDQVTDTCRANSATSRKRRVLTPNDLKHLVVDEDHELIYCYVPKVACTNWKRLMMVLTGRGKYSDPMEIPANEAHVSANLKTLNQYSIPEINHRLKSYMKFLFVREPFERLVSAYRNKFTQKYNISFHKRYGTKIIKRQRKNATQEALRKGDDVKFEEFVAYLIDPHTQREEPFNEHWQTVYSLCHPCHIHYDLVGKYETLEEDSNYVLQLAGVGSYLKFPTYAKSTRTTDEMTTEFFQNISSEHQTQLYEVYKLDFLMFNYSVPSYLKLE
Protein: Glucose-1-phosphate adenylyltransferase large subunit 1, chloroplastic (EC 2.7.7.27) (ADP-glucose pyrophosphorylase) (ADP-glucose synthase) (AGPase S) (Alpha-D-glucose-1-phosphate adenyl transferase) (P55229)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Granule-bound starch synthase 1, chloroplastic/amyloplastic
- Phosphoglucomutase, chloroplastic
- Probable phosphoglucomutase, cytoplasmic 1
- Probable phosphoglucomutase, cytoplasmic 2
- Probable starch synthase 4, chloroplastic/amyloplastic
- Sucrose synthase 3
- Sucrose synthase 1
- Sucrose synthase 6
- Sucrose synthase 5
- Sucrose synthase 2
Sequence:
MVVSADCRISLSAPSCIRSSSTGLTRHIKLGSFCNGELMGKKLNLSQLPNIRLRSSTNFSQKRILMSLNSVAGESKVQELETEKRDPRTVASIILGGGAGTRLFPLTKRRAKPAVPIGGAYRLIDVPMSNCINSGINKVYILTQYNSASLNRHLARAYNSNGLGFGDGYVEVLAATQTPGESGKRWFQGTADAVRQFHWLFEDARSKDIEDVLILSGDHLYRMDYMDFIQDHRQSGADISISCIPIDDRRASDFGLMKIDDKGRVISFSEKPKGDDLKAMAVDTTILGLSKEEAEKKPYIASMGVYVFKKEILLNLLRWRFPTANDFGSEIIPFSAKEFYVNAYLFNDYWEDIGTIRSFFEANLALTEHPGAFSFYDAAKPIYTSRRNLPPSKIDNSKLIDSIISHGSFLTNCLIEHSIVGIRSRVGSNVQLKDTVMLGADYYETEAEVAALLAEGNVPIGIGENTKIQECIIDKNARVGKNVIIANSEGIQEADRSSDGFYIRSGITVILKNSVIKDGVVI
Protein: 3-succinoylsemialdehyde-pyridine dehydrogenase (SAPD) (EC 1.2.1.83) (H8ZPX2)
Organism: Pseudomonas sp
Function: Catalyzes the dehydrogenation of 3-succinoylsemialdehyde-pyridine to 3-succinoyl-pyridine in the nicotine degradation pathway.
Interaction partners:
Sequence:
MRDYREFYIDGQWVRPKGAREAEVINPATEKIVGLISLGTEEHVDLAVRAARRAFDGWSRTSKDQRLELLEQVCRAFESKLDEIAKAITEEMGAPLVQLALPLQAPAGLGHFLTAASILRDYDFEESLGTTRVVREPAGVCGLITPWNWPLNQIAAKVAPALAAGCTMVLKPSEIAPFSAYLLARIFDEVGVPPGVFNLVNGDGPGVGAPLAAHPEVDLVSFTGSTRAGTLVSTAAAPTVKRVALELGGKSANIILDDADLETAVKHGVRTMMLNTGQSCNAPSRMLVPLSKLDEVEHLAEHFCKEIVVGDPMHSDTNIGPLASGMQYEKVQDCIRQGVAEGAKLICGGLGRPDGLESGYFAQPTIFSAVNKQMYIAREEIFGPVLCIMPYGDENEAIQIANDSCYGLSGYVSSGSLERARNVAKQLRTGAVHLNGAALDFTAPFGGYKQSGNGREWGKYGFEEFLEIKAVMGYEGS
Protein: Glutathione peroxidase (Q6ESJ0)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
- Glutathione hydrolase
- Glutathione synthetase
- Glutathione reductase
- Probable glutathione S-transferase DHAR1, cytosolic
- Os01g0151400 protein
- Os01g0151500 protein
- Glutathione reductase, cytosolic
- Probable glutathione S-transferase DHAR2, chloroplastic
- Os11g0125601 protein
- Glutathione S-transferase 3, mitochondrial
Sequence:
MPSRTAPFISRLRLLRTAAALSPFSSSAPPRHSPRILRAIPVGAPHPPRVSAAVSPLVRPVAAGFALFSMATAASSAASVHDFTVKDASGKDVDLSTFKGKVLLIVNVASQCGLTNSNYTELSQLYEKYKDQGFEILAFPCNQFGGQEPGTNEEIVQFACTRFKAEYPIFDKVDVNGDNTAPIYKFLKSSKGGLFGDNIKWNFSKFLVDKEGRVVERYAPTTSPLSMEKDIKKLLGSS
Protein: LD11117p (Lipophorin receptor 2, isoform E) (Q7YU01)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- Terribly reduced optic lobes, isoform AT
Sequence:
MATTCMPHFTEYFQTTTQSELTTNESANSRSSSSSSGCREPSKTSGFFYSASTHYQSKVQQLISFSFTSSFHLLFITCILSISKFCNAAAVNAAHVTAATPTASEIMHNLSGSALLERLKASTLGPTLDQLKHLAPAAANSISPGTGSGMGIGMGHFGSSINSVLNGNPLKFLNVSGKIGTPLDISLGLSNYCDEKQFQCSTGECIPIRFVCDGSSDCPDHSDERLEECKFTESTCSQEQFRCGNGKCIPRRWVCDRENDCADGSDESTSQCRSHTCSPEEFACKSGEGECIPLSWMCDQNKDCRDGSDEAQCNRTCRSDEFTCGNGRCIQNRFKCDDDDDCGDGSDEKNCGEKAKCGSNFFACKSGPCIPNQWVCDGDSDCRNGEDEMQNCTVSLLNFCQAGEFQCSDRITCLHKSWVCDGEADCPDGEDESQSNCLKVSCRPDQFQCNDQSCIAGHLTCNGKRDCADGSDEIMCDISATPRTCNATTEFDCGGGLCIPNAKVCNRRKDCPNGEDEPAGKCGINECSSKNGGCMHQCVNLEVGYRCECHDGYKLGADQHTCVDIDECETPGICSQVCVNEIGAFKCECEAGYMRLLKNHTRCKASEGHASLLLARRHDIRKIALDRPEMTSIVNSTKAATALDFVFRTGMIFWSDVATQSIYKAPIDEGNDRTVVLTKSSVTSDGLAVDWIYNHVYFTDTHKCTIELTNFEGSMGKVLVKDSLDIPRSIALDPIEGWMYWSDWGASPRIERAGMDGTHRTAIITYDVKWPNGITLDLVQKRLYWVDGKLNTISSSNYDGSQRHQVLYSGEYLRHPFSITTFEDYVYWTDWDKQAVFKANKFNGMDVEPVTATHMLEHPMVVHVYHPYRQPDGVNHCQSVNGHCSHLCLPAPRINERSPRISCACPTGLKLMPDGLMCVEDLGIPTVRPTAPMHRTIEQSSNSTTKLPQDGYSETPVETKTGNNRTDTSNQVHKSDAESENDYVEIALHVIASLAGTALVASVIYVVYRRCTRAVNSMNFENPVYHKTTEDHFSLEKNGTPHIYAAANDEEAVNPLFKSGTECV
Protein: Thiamine-binding periplasmic protein (P31550)
Organism: Escherichia coli (strain K12)
Function: Part of the ABC transporter complex ThiBPQ involved in thiamine import. Binds thiamine, thiamine phosphate and thiamine diphosphate with high affinity.
Subcellular location: Periplasm {ECO:0000269|PubMed:12182833}.
Interaction partners:
- Thiamine transport system permease protein ThiP
- Thiamine import ATP-binding protein ThiQ
- Hydroxyethylthiazole kinase
- HTH-type transcriptional regulator SgrR
Sequence:
MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAFEADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVAADAVNVPGGWNNDTFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRTSTPGLGLLLWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTSPAYHILEEKKDNYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIPTGNWMYPVANVTLPAGFEKLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR
Protein: Subtilisin-like protease SBT3.15 (EC 3.4.21.-) (Subtilase subfamily 3 member 15) (AtSBT3.15) (F4JJL8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Secreted {ECO:0000250|UniProtKB:Q84WS0}.
Interaction partners:
Sequence:
MENSFLSSKLVFLLAIALVLFLNTELSFLTAEGASDSNSKVYIVYLGQREHDDPELLTASHHQMLESLLQSKEDAHNSMIYSYQHGFSGFAALLTSSQAKKISEHPEVIHVIPNRILKLKTTRIWDHLGLSPIPTSFSSSSSAKAKGLLHNTSMGSEAIIGVVDSGIWPESKVFNDQGLGPIPKRWRGKCRSGEKFNATMHCNKKLIGAKYYQSGLLAMNGGKFNRIIIRDFKSNRDATGHGTHTATIAGGSFVPNASFYGLARGTVRGGAPRARIASYKACWNVVGWGGICSSADMWKAYDDAIHDQVDVLSVSIGASIPEDSERVDFIAAFHAVAKGITVVAAAGNDGSGAQTICNVAPWLLTVAATTLDRSFPTKITLGNNQTFFVSNLAESLFTGPEISTGLAFLDDDVDVKGKTILEFDSTHPSSIAGRGVVAVILAKKPDDRPAPDNSYIFTDYEIGTHILQYIRTTRSPTVRISAATTLTGQPATPKVAAFSSRGPNSVSPAILKPDIAAPGVSILAAVSPLDPGAFNGFKLHSGTSMSTPVVSGIIVLLKSLHPKWSPAAMRSALVTTAWRTSPSGEPIFAQGSNKKLADPFDYGGGLVNPEKAAKPGLVYDMGIKDYINYMCSAGYNDSSISRVLGKKTKCPIPKPSMLDINLPSITIPNLEKEVTLTRTVTNVGPIKSVYRAVIESPLGITLTVNPTILVFKSAAKRVLTFSVKAKTSHKVNSGYFFGSLTWTDGVHDVTIPVSVKTTISM
Protein: Hepatitis A virus cellular receptor 1 (Kidney injury molecule 1) (Zgc:92647) (Q6DH50)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MTDLHSWFLSSWILCCLTICRCSDIIVQSFEGDNVTLPCKYDSRYHGKCEICWMRGDIPSRGCGEEIIASDGDKVSTRNSDRYDLAGPIQHGDVSLTIFNIDKTDSGKYGCRVHVPGWFNDEKYYVHLIVDDDNKTRKEISSTISPSYAPRSSTAGMWLSNTTSVEPSVSVVYHESSSAESKDNVTVSAVLVPVLLLLLALIAIAAAFMWKQKKKTRASLEVRQNSEISVIYSNSGSSVGLYNREMAVENVYQIQAESEYEQWH
Protein: histone deacetylase (EC 3.5.1.98) (Q5ADP0)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Transcriptional regulator
- Transcriptional regulatory protein SDS3
- Chromatin modification-related protein EAF3
- Histone deacetylase
- Ume1p
- Transcription regulator
- PHD-type domain-containing protein
- 4-nitrophenylphosphatase
- Histone acetyltransferase type B subunit 2
- Zinc finger PHD-type domain-containing protein
Sequence:
MYTELPFDELKVDPNQKKRIAYFYDADIGNYAYGAGHPMKPHRIRMAHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDFISRVNPDNLDLFTKEQIKFNVGDDCPVFDGLFEYCGISGGGSMEGAARLNRGKCDIAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVEEAFYTTDRVMTCSFHKYGEFFPGTGELRDIGVGKGKYHSVNVPLRDGIDDATYKSVFEPVISKIIEWYQPSAIVLQCGGDSLSGDRLGCFNLSMNGHANCINYVKSFNIPMMVVGGGGYTMRNVARTWAYESGLLNNVKLPDELPYNEYYEYYGPDYKLDVRSSNMFNQNSPEFLDKILTNIIANLENTKHAPSVQMNEVPNDPEDLGDVEEDTAMAIDTKGGSEMSRDAQIQPDNEFYEDDEKDKGEKAIIDNKHEDQDSMQVDKSEEPVVEQKDKPQDENNVTGDNIEEDQPQEVNPIEEQPSVEKSVVVVEDKLEEVKPVEQKVEEPKEVVDKPEDKHEDKPAETLTETTTESKPEDQPMEDAAKLTEEELKEIEELNKSS
Protein: Arylacetamide deacetylase (EC 3.1.1.3) (50 kDa microsomal esterase/N-deacetylase) (Q7M370)
Organism: Oryctolagus cuniculus (Rabbit)
Function: Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly. Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity (By similarity).
Subcellular location: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Microsome membrane; Single-pass type II membrane protein.
Interaction partners:
- B1 bradykinin receptor
- B2 bradykinin receptor
- Carboxylic ester hydrolase
Sequence:
GVKTVLLLIVGVLGAYYVYTPLPDNIEEPWRLLWVNAHMKTLTNLALFAEYLGSNIFMNTVKFLTSFQEVPPTSDENVTVTETTFNNVPVRVYVPKRKSKTLRRGLFYIHGGGWCVGSAALSGYDLLSRRTADRLDVVVVSTNYRLAPEYHFPIQFEDVYDALKWFLRQDVLEKYGVDPERVGVSGDSAGGNLAAAVAQQLIKDPDVKIKLKTQSLIYPALQTLDMDLPSYRENAQFPILSKSFMVRLWSEYFTSDRSLEKAMLLNQHVPVESSHLFKFTNWSSLLPEKFKKGHVYNTPTYGSSELARKYPGFLDVRAAPLLADDAQLRGFPLTYVITCQYDVLRDDGVMYVTRLRNAGVQVTHNHIEDGFHGALSYNGFKTGYRVEKQYFEWLRENV
Protein: Amidase enhancer (Q55763)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Interaction partners:
Sequence:
MFISPPRNLLKVAVQRVGGLVIALGLVAGGALPSFAKDVLLQVGVVQRFGDEDRDQLTISGVGNDDLTFTAVNNQGEKVTLQGKQGTIAISRRAVPRKLAEVLVLGDHATFETAEDDALRWQAQGIAVEVTQPGRWQVWAKRDVYDSPLVRRWLLADLKKQGHQLPYLESVLLDSKPQAMVVINGQSYPADRVTVTAAKNQIQVTEGEKKFVYGGWLQLQPNSYGNYTLVNHVPLETYLRGVVPHEIGPGAPPTAAKAQTIIARTYALQNRRRFAADGYELCATTHCQVYYGLSGTTPRADEAIKETAGQVLTYNNQLVDALYSSTAGGVTAKFSDVWNGEERPYLQAVIDSAQPIWNLSTQSLADEATFRKFINLQEGFNETGRKFLRWRYPATLAELNQDLKKYLTNRRHPLADFTTIYDMKVTRRSPSGRILLLEVLTDKGVVELAKNEARSAFGPPRSTLFYLEPTYDANQRLQSVFFVGGGFGHGVGMSQFGSYKLSQLGWSAEQILAFYYPGTQIRQLNEQILGQTPRP
Protein: Pyridoxal 5'-phosphate synthase subunit PdxT (EC 4.3.3.6) (Pdx2) (Pyridoxal 5'-phosphate synthase glutaminase subunit) (EC 3.5.1.2) (P37528)
Organism: Bacillus subtilis (strain 168)
Function: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
Interaction partners:
- Pyridoxal 5'-phosphate synthase subunit PdxS
- Pyridoxine kinase
- GMP synthase
- Transaldolase
- Ribokinase
- Ribose-phosphate pyrophosphokinase
- Transketolase
- Phosphopentomutase
- Phosphoglucomutase
- Putative sugar phosphate isomerase YwlF
Sequence:
MLTIGVLGLQGAVREHIHAIEACGAAGLVVKRPEQLNEVDGLILPGGESTTMRRLIDTYQFMEPLREFAAQGKPMFGTCAGLIILAKEIAGSDNPHLGLLNVVVERNSFGRQVDSFEADLTIKGLDEPFTGVFIRAPHILEAGENVEVLSEHNGRIVAAKQGQFLGCSFHPELTEDHRVTQLFVEMVEEYKQKALV
Protein: rRNA-processing protein FYV7 (Function required for yeast viability protein 7) (Q12247)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in the processing of the 20S pre-rRNA. Required for survival upon K1 Killer toxin exposure.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Probable ATP-dependent RNA helicase DHR2
- Nucleolar protein 16
- rRNA biogenesis protein RRP36
- Nucleolar protein 6
- rRNA-processing protein EFG1
- KRR1 small subunit processome component
- rRNA-processing protein CGR1
- 60S ribosomal subunit assembly/export protein LOC1
- Probable ATP-dependent RNA helicase DHR1
- rRNA biogenesis protein RRP5
Sequence:
MGTAKQNQNRKKFTREYKVKEIQRSITKKTRLRKEYLKALKDEGYAVPEKEPKTVAKESVRKIKEARAIEGKKKLDEKKEIKKQRKRMQKDELNKQRNEQLERIRVSKEKFQRREDRKKKLTQRTRTGQPLMGPKIEDLLDKIKTDDTYTS
Protein: Protein farnesyltransferase subunit beta (FTase-beta) (PFTase beta) (EC 2.5.1.58) (CAAX farnesyltransferase subunit beta) (Ras proteins prenyltransferase subunit beta) (G4MY67)
Organism: Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Magnaporthe oryzae)
Function: Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The beta subunit is responsible for peptide-binding.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:31250536}.
Interaction partners:
- Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
- intramembrane prenyl-peptidase Rce1
- CAAX prenyl protease
- Farnesyl pyrophosphate synthase
- Alkyl transferase
- Hexaprenyl pyrophosphate synthase
- ditrans,polycis-polyprenyl diphosphate synthase [
- Geranylgeranyl pyrophosphate synthetase
- Geranylgeranyl pyrophosphate synthase
- Squalene synthase
Sequence:
MRHHTKNLRRRAIFLRTTPRGNMDSSSSVATSTSSSSNHRLVRSSEGSPSAGGDDIEEVIMTPGIATGRVQPAVSVAIPDLFTQLPPVKDDLATSTSKTQDETVAICLPYLAGSDANADVEHNAHGVPHIDRKKHVRFLRNMLRQLPAPFIAADASRPWFLYWSLNAMAILGENVKEDYAESLADTARSMQNESGGFSGGHGQTSHLATTYAVVLALAVVGDEEGLSLIDRRALWKWLCDLKEADGGFRMSLGGEEDVRGAYCAAVIISLLNLPLDLCKDSEAYIRDPTANLFTGLGDYVRKCQTFEGGISGQPDAEAHGAYAFCALGCLSLLGTPSETIPKYLNIERLISWLSSRQYAPEGGFSGRTNKLVDGCYSHWVGGCWPLIEACLNGPVKVSSLDVEPQPLFSREGLMRYILCCCQEQGKRGGLRDKPGKPSDAYHSCYVLSGLSSAQNRWQLVVGDDDMPAWMVSPFPNEEEIFDEKDRVGTVHPVYVIPEDKVAKVQTFFASRDGF
Protein: Dynamin-binding protein (Scaffold protein Tuba) (E7F1U2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton (By similarity). Plays a central role in renal ciliogenesis and kidney development.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q6XZF7}. Golgi apparatus, Golgi stack {ECO:0000250|UniProtKB:Q6TXD4}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q6TXD4}. Synapse {ECO:0000250|UniProtKB:M0R4F8}. Cell junction {ECO:0000250|UniProtKB:Q6XZF7}.
Interaction partners:
- S phase cyclin A-associated protein in the endoplasmic reticulum
- isoleucine--tRNA ligase
Sequence:
MEAGSVVRAVFEFLPSVSEELPLFTGDVIEVLSVVDEFWLLGNKDGVTGQFPTTFVESVTIPGTKAGENLYVCINDFNSAEAGNLPLKRGDVVAAESSMDSVWMRGHNAWGSRGLFPVSCIKELELSGRSRQLSERSAAVQASELPPHALGQARALMNLHAQLDEELDFREGDVITIIGLPEPGWFQGELDNRTGLFPEGFVELLGPLRSPLEEPEPQTLEQYPDYSNEDEERRAEEEKDEEPPEMEIQQCQEDEEEEEGAIYGIALYEFRALEPGELDFDVGDRIRILASMDDGWLEGQIHSRRGVFPHRFVKIEGQLQTVPQTETLINEISVPKREEECYTPDYTSAEEDHTVPEYGQELSIQQDHTVWDLDYFERREEEQKENNGHNVHSDQSSQERRMTQNQSQVQPQERRRDRPPPPQTQPNRGSSSAHRSVQINRRSSPNMGRPQLPPRPSLHALSNRKYSTGSHASLRQPPPAPITMNQSLNPPNKTSPNSTWTRNNGKYASYNSRNPLSSKSSGEKNRQKKLTRHASVNDADIISGGSSEQQAWPQVQGSNGFPTSQTMGTLALSAKDLEAKLSQQLIEFEKSLPSHSNEATEQSRWEEVSGRLGNKVSRHFSIMDYSDENDIIRGSSHSSIERLLPSTSSPSGSASSSLERRKNLRPPPPRPRVLRPPAPTNTHWSQTNGRITPQPYRPARPAPRPPPPCPHTNAVTPPTTSNPFYNSPDEEEIVEEMEEPEDVLEAEKEMEREQEQYRLLLRLEEVEREIDMYSNTAQELQAMLDEEQDETSRQQALENLEFCSYTMETLTLEQQQLQEMTLLASQPKSLESSPASAANSEDPELRMLEKRTKVIEELLQTEHDYIKDLQMCVKEIIQPLQKKQVQGIDFDGLFGNISSVIDLSRRLNKTLQDTDSIGQVFLSYKDQLEDVYKIYCQNHDDAISLLETYEKDENIQKHVLECLEKLRGIYREWGKTNYINLGSFLIKPVQRVMRYPLLLMELLNTTPESHHDRQQLSEAVMSIKEINVNINEYKRRKDLVVKYRKGDEDRLIDKISKLSMHSIIKKSNRVSSHLKHLTGISPQIKDEAFDDAEKRFRLQERLIKSFIRNISLYLQHIRESASVKVLAAISFCDIYTERQQQMDPERFQRAHRCISDKQFTEFKERTEALVITPLTQLLNMFTGPHKLIQKRRDKLLDYDNCKERAERLKDKRVQEELQTARNNYEALNAQLLDELPKFHRAAEDLFTSCVRGFVQAQRDFISLTLGELTPLLQLSGLGGTEGNLVSLFQEEHTRVLDLLQSFSFFPENLPTTVRKTFEKKTLEKQYTKKPQAPPNYVLQTDEHRAGLLVRYGPENLYQAERNFNAAQDLDVSVLEGDIVGVIKQQDPMGSQNRWLIDNGVTKGFVYSSFLKPYNPRRSQSDVSIESQSSNESGYGGSSPMFSRQNSNSTLTFNQETSTVSFTTATTQNQSNTRPNNESTPRKIRETSSNQRDSLEPGFRNSPNHKEVSETAIRNSREYSEPSHRSSTNHRDSVDSDQNTPTNSRDRLDLSETDSSSSRNSRYEPSSRYQDSKASYGSHQRQNGDYSGQQRRPQYTPEEYIEPEPEPEIDGHQIYYALYSFSARCANELSISANQRVRILEFQDMNGNQEWWLGEAGGRRGYVPSNYIRKSEYT
Protein: FBD domain-containing protein (Q9N2V7)
Organism: Caenorhabditis elegans
Interaction partners:
- N-terminal acetyltransferase B complex subunit NAA25 homolog
- C2H2-type domain-containing protein
- F-box domain-containing protein
- Sun domain-containing protein 1
Sequence:
MVPKRVLLSDIDFYRNFLFLIFNHFNFEMASSVTTSLNFSNLESPKSNSSSLFEDSLFSSFRWKRTPERAPSNNELVEHGDLENFEYSEPFVIKFHNICKGGGERVNGQPKMDVACQLDDFIEVPIKDAENCLECMTDDRILLDSVEIEVKICTTTCKLAIESILEKYAERRERCKSIVMVKRLVFFIYDLTYAKELAPILARIAPRACIVNLGIPKTKTFPLPPPIECRYVAEFIADFLRGRNAWQTIRVLRVFYFVSLDLNLQKILKKCVCLRHLTLSNVEDVGVFELDTVNSVLLDSCDFSITMMDEVFAEKHPRLFPNATNFGFHRSPISLCLKALKEWSRDRIADTRKTLCFYQPERDFRKFLFEASKLFEVVDDDNELEGEVQIKGQSGGCPLITVFNKDRVYKARI