wanglab/gogpt-training-data huggingface dataset:
Protein: Periplasmic beta-glucosidase (EC 3.2.1.21) (Beta-D-glucoside glucohydrolase) (Cellobiase) (Gentiobiase) (P33363)
Organism: Escherichia coli (strain K12)
Subcellular location: Periplasm.
Interaction partners:
- 6-phospho-beta-glucosidase BglB
- 6-phospho-beta-glucosidase AscB
- 6-phospho-beta-glucosidase BglA
- Endoglucanase
- 6-phospho-beta-glucosidase
- Maltodextrin glucosidase
- PTS system N,N'-diacetylchitobiose-specific EIIC component
Sequence:
MKWLCSVGIAVSLALQPALADDLFGNHPLTPEARDAFVTELLKKMTVDEKIGQLRLISVGPDNPKEAIREMIKDGQVGAIFNTVTRQDIRAMQDQVMELSRLKIPLFFAYDVLHGQRTVFPISLGLASSFNLDAVKTVGRVSAYEAADDGLNMTWAPMVDVSRDPRWGRASEGFGEDTYLTSTMGKTMVEAMQGKSPADRYSVMTSVKHFAAYGAVEGGKEYNTVDMSPQRLFNDYMPPYKAGLDAGSGAVMVALNSLNGTPATSDSWLLKDVLRDQWGFKGITVSDHGAIKELIKHGTAADPEDAVRVALKSGINMSMSDEYYSKYLPGLIKSGKVTMAELDDAARHVLNVKYDMGLFNDPYSHLGPKESDPVDTNAESRLHRKEAREVARESLVLLKNRLETLPLKKSATIAVVGPLADSKRDVMGSWSAAGVADQSVTVLTGIKNAVGENGKVLYAKGANVTSDKGIIDFLNQYEEAVKVDPRSPQEMIDEAVQTAKQSDVVVAVVGEAQGMAHEASSRTDITIPQSQRDLIAALKATGKPLVLVLMNGRPLALVKEDQQADAILETWFAGTEGGNAIADVLFGDYNPSGKLPMSFPRSVGQIPVYYSHLNTGRPYNADKPNKYTSRYFDEANGALYPFGYGLSYTTFTVSDVKLSAPTMKRDGKVTASVQVTNTGKREGATVVQMYLQDVTASMSRPVKQLKGFEKITLKPGETQTVSFPIDIEALKFWNQQMKYDAEPGKFNVFIGTDSARVKKGEFELL
Protein: Sterol regulatory element-binding protein cleavage-activating protein (E9QEH6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000256|ARBA:ARBA00004557}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004557}. Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}. Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004653}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004653}.
Interaction partners:
- Sterol regulatory element-binding protein 2
- Sterol regulatory element-binding transcription factor 1.
- Insulin-induced gene 1 protein
- Insulin-induced gene protein
- Membrane-bound transcription factor site-1 protease
- Membrane-bound transcription factor peptidase, site 2.
Sequence:
MTVRERLRQNISAAFYRHGLLCASYPVPIILFTSASILTCCYPLLKLPLPGTGPVEFTTGVRDYSIPSHESQGDLSERPDWYRGPPVAYIQQVLVKAAVSPWGNSLVPVDVFRSPLGRVFSLLDEIRNHVYTDRSLEALCLQVTDLLPGLRRMQAVLPEHGCLLVSPGNYWQNRRDLFDADPDLLKTVHQHEPKGLHTSATLRDLLFGVPGKQTGVSLYSKKRVVTYTVTIALSSYDARFVGSLRARLKQLHPSANCTLREDHMVHVHFKEEIGIAELIPLVTTYIILFAYIYFSTRKIDMVRSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLSNESWSIMKNMATELCIILIGYFTFVPAIQEFCLFAVVGLVSDFFLQMFFFTTVLSIDIRRMELADLNRRLPAEAGMPPPKPGTLRPRETPPPPRPSPHTITLQTPAFRNLRLPKRLRVVYFLARTRLAQRIIMVGTVIWIGILVYTDPAGLRTFLAAQVSEQSPLGEAGLPPHLGVAPVFPGGHPTSTLSVLPAPEPTPLPENQSQGHRAARPGVAPVSSPQITWGSEDEELWRRLSFRHWPSLFSYYNITLAKRYISILPVIPVTLHLSPQEAIDTRHPQDTQHAPPPPPSIKTSDLQTDLTLYKVAALGLFAGVLLVLLLFCLYRVLCPRNYGQNGVPHGRRRRGDLPCDEYGYSPPISEISPLLLRGHSMDIECLASDGMLLASCCLAGQIRVWDAQTGDCLTVIPNKGLRRSSSNGCWEHRDGWDHISAFEVEGIATDFREPGGAMGGPDVDIFAIRRRTTPARPALFGDQPDLTPLIDTNFGALPPSQALSGSGFDFGSLVEKAYQEHEPSPVLVFPPSPPASQQRRRSLGDQPVLPPELPPQSSADWDSSVWAMELRGNLIATGRSTGKLELWDAVEGSLRCSNEDGVSGITALAFLNNRIVAARLNGSLDFFTVEINKPLGLLQYRGPPGRGSLPPSPCYSSEDVISCHLTRSVQCAHQKPITVLKAAAGRVVTGSQDHTVRVYRLEDSCCLFTLQGHSGGITAIYIDQTMVLASGGQDGAICVWDVLTGSRVSHVYGHRGDVTSLVCTTSCIISSGLDDLICIWDRSTGIKLYSIQQEVGCGASLGVISENLLVTGGQGCVSFWDLNYGDLLQTVYLGPSSEGQSVRQLLVLDNAAIICDFGSELSLVYVPSVLEKLD
Protein: Serine hydroxymethyltransferase (EC 2.1.2.1) (Q7SXN1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSQRNGHTEKTWESHNKMMLEPLSTNDPEVFDIIKKEKKRQTYGLELIASENFTSRAVLEALGSCMNNKYSEGYPGQRYYGGTEHVDELERLCQDRALKVYGLDPEKWGVNVQPYSGSRANFAVYTAIVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPETGYIDYNRLEENARLFHPRLIIAGTSCYSRNLDYSRLRKIADENGAYLLADMAHISGLVAAGVVPSPFEYCDVVSTTTHKTLRGCRAGVIFFRKGVRSVDAKTGKETMYNLESLINQAVFPGLQGGPHNHAIAGVAVALKQALTPEFKTYQLQVLANCKALASALMDKGYKVVTGGSDNHLILVDLRSNGTDGGRAEKVLEACAIACNKNTCPGDKSALRPSGLRLGSPALTSRGLLEEHFHKVAEFIHQGIVLTLEIQKNMNPKATLKEFKEELSQNEKYQLKTKEIRKEVEDFAGKFPMPGLPEL
Protein: Uncharacterized protein (Q382Q5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MTILSLHGRNGADAQKWFESGLLPFPGGQKSFEMVSVMPALVYHHCMLYWAKLGCAALLQEGSVEMTGKAGSETLMFVVRNICCIQIAESPRCLPNWRLLDRVLDELLKRLDFVANCEDGVWSFASTTMRRMQCYLRSNIIRYLEVRDRPLEGQCGLLRYRGAFDCAINGVNSSGASGMGGCQTTDEVHVEVLSAETLRSAVQVMCGCDGVKVPCGDSSGGVKDGADALADLELEEFFCRYFLCSAPAAFDQPTKPTVRE
Protein: Slit homolog 3 (Drosophila) (Slit homolog 3 protein precursor) (F1RCV3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Roundabout, axon guidance receptor, homolog 1
- Roundabout, axon guidance receptor, homolog 2
- Roundabout, axon guidance receptor, homolog 2
- Roundabout homolog 4 isoform X1)
- Netrin g1a.
Sequence:
MMRWVKYWGTVAVLCGLLSCAVNGCPHKCSCSGSHVDCQGQAFKTVPRGIPRNAERLDLDRNNITRITKVDFSGLKNLRVLHLENNQISVIERGAFEGLKQLERIRLNRNRLQVLPELLFQSTTKLSRLDLSENQIQAVPRKAFRGITTVKNLQLDSNHISCIEDGAFRALRDLEILTLNNNNITLIPLSSFNHMPKLRTLRLHSNNLHCDCHLSWLSDWLRQRRGLAPFTQCMAPAHMRGLNVPDVQKREFVCTGPVETEPRSCAPQVTICPAACTCNNNIVDCRRKGLTEIPANLPEGIVEIRLEQNMIKNIPAGAFSTYKKLKRIDLSKNQISEIAEDAFSGLRSLTSLVLYGNKIAEIPKGLFDGLVSLQLLLLNANKINCLRVNTFKDLQNLNLLSLYDNKLQTISKGLFAPLRAIKTLHLAQNPFMCDCHLKWLADYLFDNPIETSGARCSHPRRLANKRISQVKGKKFRCTGAEDYRSRLSGECFQDLVCPERCRCEGTVVDCSNLKLTKIPPHLPEHTTDLRLNDNEISILEATGAFKKLPNLRKINLSNNKLRDIREGAFDGAGGVLELLLTGNKLQSVSGRMFKGLIGLKTLMLRSNQISCVDNATFTGLSSVRLLSLYDNRISTIAPGAFNTLHSLSTINLLSNPYVCDCHLAWLGLWLKKTRVVSGNPRCQKPAFLKEIPIQDVAMPDFSCDGAEENVCLPSAPRCPESCTCSETVVRCSNRGLRSLPKTIPKDTTELYLEGNLLTSVPKELPNLKQLTLLDLSNNSISHLAPLTFSNMTQLATLILSYNQIRCVPVHAFDGLRSLRLLTLHGNDLSTVPEGAFNHLTSLSHLALGANPLYCDCELRWLSQWVKAGFKEPGIARCTGPPDMADRLLLTTPLNRFQCKGPADLNLMSKCAPCLATPCQNNGTCVSDVTGSYHCTCPFGYKGRNCEIPINACISLPCTNGGTCHLTPGLDGQYSCVCPPGYEGQQCELNPDDCEDNDCENNSTCVDGINNYTCVCPPNYKGDLCEEVVDPCLPGFDLCQHDSKCVPLSKGYRCECLPGYVGQQCEQDYNDCLENKCQHGAECVDAINGYTCVCKEGFSGLFCENHPPMVLLQNTSPCDQSDCQNGSECLVMEGEPVCRCLPGYFGTKCQKMVTLHFLGKEAYVELSGTRIRPPMHISFQVATDKDNGILLYKEDHDPLALELYQGHIRLIYDISKYPPTTVYSVESVNDGLFHTVEVLIQNQTLSLVVDKGTPKSLGKLPRPPAVDHNTQLYIGGVPSLIGTSGLRPGPFQSFNGCLHDVRLNGELQDLGAGLAGIEGVLFGCHSCSVCDQGACRQRGDEGVTCDCPTGHSGPLCEQMSSQDPCESSRCVHGECVAKGSSYSCLCVDGYSGQFCDRQDESSACKGLHCVYGECRLTESGEPACHCQPGYSGPTCETELTCEGEAVRDYLYRQMAHKICTSTSRVQRLECRHSCSSGLCCAPTKSRRRKLSFKCPDGSSFSEEMEITVECGCTKCSS
Protein: Uncharacterized protein C1orf198 (Q9H425)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:22361696}.
Interaction partners:
- Cytochrome c oxidase subunit 5A, mitochondrial
- Cytochrome c oxidase subunit 7C, mitochondrial
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Cytochrome b-c1 complex subunit 8
- Cytochrome b-c1 complex subunit 7
- Cytochrome c1, heme protein, mitochondrial
- Cytochrome b-c1 complex subunit 9
- Cytochrome c oxidase subunit 3
- Cytochrome c oxidase subunit 2
- Cytochrome b-c1 complex subunit 2, mitochondrial
Sequence:
MASMAAAIAASRSAVMSGNRPLDDRERKRFTYFSSLSPMARKIMQDKEKIREKYGPEWARLPPAQQDEIIDRCLVGPRAPAPRDPGDSEELTRFPGLRGPTGQKVVRFGDEDLTWQDEHSAPFSWETKSQMEFSISALSIQEPSNGTAASEPRPLSKASQGSQALKSSQGSRSSSLDALGPTRKEEEASFWKINAERSRGEGPEAEFQSLTPSQIKSMEKGEKVLPPCYRQEPAPKDREAKVERPSTLRQEQRPLPNVSTERERPQPVQAFSSALHEAAPSQLEGKLPSPDVRQDDGEDTLFSEPKFAQVSSSNVVLKTGFDFLDNW
Protein: ATP-dependent RNA helicase DHX30 (EC 3.6.4.13) (DEAH box protein 30) (Q99PU8)
Organism: Mus musculus (Mouse)
Function: RNA-dependent helicase. Plays an important role in the assembly of the mitochondrial large ribosomal subunit (By similarity). Required for optimal function of the zinc-finger antiviral protein ZC3HAV1 (By similarity). Associates with mitochondrial DNA (By similarity). Involved in nervous system development and differentiation through its involvement in the up-regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:25219788}. Mitochondrion {ECO:0000250|UniProtKB:Q7L2E3}. Mitochondrion matrix, mitochondrion nucleoid {ECO:0000250|UniProtKB:Q7L2E3}. Note=Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids. Relocalizes to stress granules upon heat stress. {ECO:0000250|UniProtKB:Q7L2E3}.
Interaction partners:
- Probable ATP-dependent RNA helicase DDX28
- DNA-directed RNA polymerase, mitochondrial
- Small ribosomal subunit protein mS39
- G-rich sequence factor 1
- FAST kinase domain-containing protein 2
- FAST kinase domain-containing protein 3
Sequence:
MVTPVCNSSTWQPKDSSFLSWPEMFSLDSFRKDRTQHRQRQCKLPPPRLPPMCVNPAPGGTITRASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEGYGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPTMPPTSWRQLNPENIRPGGPAGLSRSLGREEEEDEEEELEEGTIDVTEFLSMTQQDSHNPLRDSRGGSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLATLTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIEAFLSHYPVDSSWISPELRLQSDDILPLGKDSGPLSDPITGKPYMPLSEAEEVRLSQSLLELWRRRGPIWQEAPQLPVDPHRDTILSAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPARGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYPHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPLGVRKIVLATNIAETSITVNDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRTSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLPSAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLREFRRALGRMVERSLRSELAALPLSVQQEHGQLLALLAELLRGPCGSFDMRKTADD
Protein: Toll/interleukin-1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (Adaptor protein Wyatt) (MyD88 adapter-like protein) (Q99JY1)
Organism: Mus musculus (Mouse)
Function: Adapter involved in the TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response (By similarity). Positively regulates the production of TNF-alpha and interleukin-6 (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Membrane {ECO:0000250}. Note=Colocalizes with DAB2IP at the plasma membrane. {ECO:0000250}.
Interaction partners:
- TNF receptor-associated factor 6
- Toll-like receptor 4
- Myeloid differentiation primary response protein MyD88
- Toll-like receptor 2
- Interleukin-1 receptor-associated kinase 1
- Interleukin-1 receptor-associated kinase 4
- Toll-like receptor 6
- Toll-like receptor 9
- Lymphocyte antigen 96
- Toll-like receptor 3
Sequence:
MASSSSVPASSTPSKKPRDKIADWFRQALLKKPKKMPISQESHLYDGSQTATQDGLSPSSCSSPPSHSSPESRSSPSSCSSGMSPTSPPTHVDSSSSSSGRWSKDYDVCVCHSEEDLEAAQELVSYLEGSQASLRCFLQLRDAAPGGAIVSELCQALSRSHCRALLITPGFLRDPWCKYQMLQALTEAPASEGCTIPLLSGLSRAAYPPELRFMYYVDGRGKDGGFYQVKEAVIHYLETLS
Protein: NF-kappa-B-activating protein (NFKB activating protein) (dNKAP) (Q9VB74)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000269|PubMed:38059855}.
Interaction partners:
- CBF1-interacting co-repressor CIR N-terminal domain-containing protein
- FI16123p1
- Pre-mRNA-processing factor 19
- Pre-mRNA-splicing factor 38
- Uncharacterized protein, isoform B
- LD03179p
- GEO11163p1
Sequence:
MRSRSRSRSRQRERRRSDSRARSRSERRTYQKPQHRRSVSRERKRERDRELHRERTSNRSSRRSREKDAVPRRRRTRSSPSRSSSSSSSDRSSSSRSPSRSRKSRPKSVERWPNDRYHENNDRRQNPFRGRAPEGSFINDPAEPSFRSQHRGRGSSNHQFKGDSKAVNARRNQRVLIGEEGVPEVWGKSPSRPETDDVELVKGSYIGPKKKKKKGKRKHKKSEKKSKKKSKKSKKKKSKQESSSSSSSSSSEDSSDESSSSSSSSSSDSEDESEEEDVWLEKTADGIKKPKKKKSSTSKKDKKSKKKKKKRKSEAEKSKKSSSSSASKSKNKESASHNDEDVGPSLRPGGSLNQKDFGKALLPGEGAAMAAYIAEGKRIPRRGEIGLTSDEIANFESVGYVMSGSRHRRMEAVRIRKENQLYSADEKRALAMFSKEERQKRENKILSQFKDMIHSKLQAKDKK
Protein: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (EC 1.2.1.12) (Peptidyl-cysteine S-nitrosylase GAPDH) (EC 2.6.99.-) (P16858)
Organism: Mus musculus (Mouse)
Function: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton (By similarity). Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. Also plays a role in innate immunity by promoting TNF-induced NF-kappa-B activation and type I interferon production, via interaction with TRAF2 and TRAF3, respectively (By similarity). Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity).
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P04797}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P04797}. Nucleus {ECO:0000250|UniProtKB:P04797}. Note=Translocates to the nucleus following S-nitrosylation and interaction with SIAH1, which contains a nuclear localization signal. Colocalizes with CHP1 to small punctate structures along the microtubules tracks. {ECO:0000250|UniProtKB:P04797}.
Interaction partners:
- Large ribosomal subunit protein uL13
- Bifunctional glutamate/proline--tRNA ligase
- Triosephosphate isomerase
- Heterogeneous nuclear ribonucleoprotein Q
- Heat shock cognate 71 kDa protein
- Phosphoglycerate kinase 1
- Fructose-bisphosphate aldolase A
- Phosphoglycerate kinase 2
- Glucose-6-phosphate isomerase
- Fructose-bisphosphate aldolase
Sequence:
MVKVGVNGFGRIGRLVTRAAICSGKVEIVAINDPFIDLNYMVYMFQYDSTHGKFNGTVKAENGKLVINGKPITIFQERDPTNIKWGEAGAEYVVESTGVFTTMEKAGAHLKGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIVSNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGAAQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTPNVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEDQVVSCDFNSNSHSSTFDAGAGIALNDNFVKLISWYDNEYGYSNRVVDLMAYMASKE
Protein: Phosphotyrosine protein phosphatase I domain-containing protein (Q38FI3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Acyl carrier protein
- Small ribosomal subunit protein mS29
- [acyl-carrier-protein] S-malonyltransferase
- Rhodanese domain-containing protein
- Metallo-beta-lactamase domain-containing protein
- Uncharacterized protein
- tRNA pseudouridine synthase A-like protein
- Translation initiation factor IF-2
- DNA photolyase, putative
- 30S Ribosomal protein S17, putative
Sequence:
MSTSSRGILIAGLTNRARTQMAEGILRRLTAGTIFIKSGGVHHESTIHPLAVKVMKDIGIDISKQSVTSLEAARRQQNTYDVYISIDCSYERRTLDKSQPPRAEVRRRESFTVEYGDDGSGPRGGDDPVRYDPLLVPRTPSHWSVGVDATDVRRRWQIWSPRDPSIFHETSTRKFQDHLYEGEPLFMQLRQCPWRTQAKVSERWEMDEVAIRYPVERHSAHELRFVQAREQLLQRSFDLLTKLEKHYGERLLLDRALLEEFIS
Protein: Fat storage-inducing transmembrane protein 1 (Fat-inducing protein 1) (Q91V79)
Organism: Mus musculus (Mouse)
Function: Plays an important role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis (By similarity). Directly binds to diacylglycerol (DAGs) and triacylglycerol (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000255|HAMAP-Rule:MF_03229, ECO:0000269|PubMed:18160536, ECO:0000269|PubMed:22106267}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_03229}.
Interaction partners:
Sequence:
MERGPTVGAGLGAGTRVRALLGCLVKVLLWVASALLYFGSEQAARLLGSPCLRRLYHAWLAAVVIFGPLLQFHVNSRTIFASHGNFFNIKFVNSAWGWTCTFLGGFVLLVVFLATRRVAVTARHLSRLVVGAAVWRGAGRAFLLIEDLTGSCFEPLPQGLLLHELPDRKSCLAAGHQWRGYTVSSHTFLLTFCCLLMAEEAAVFAKYLAHGLPAGAPLRLVFLLNVLLLGLWNFLLLCTVIYFHQYTHKVVGAAVGTFAWYLTYGSWYHQPWSPGIPGHGLFPRSRSMRKHN
Protein: Multivesicular body sorting factor 12 (12 kDa multivesicular body sorting factor) (ESCRT-I complex subunit MVB12) (P42939)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Appears to be involved in cargo sorting and release of the ESCRT-I complex from the MVBs.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17135292}. Endosome {ECO:0000269|PubMed:17135292}. Late endosome membrane {ECO:0000305|PubMed:17135292}; Peripheral membrane protein {ECO:0000305|PubMed:17135292}.
Interaction partners:
- Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease
- Protein SRN2
- Vacuolar protein sorting-associated protein 28
- Vacuolar protein-sorting-associated protein 36
- Vacuolar protein-sorting-associated protein 25
- Vacuolar protein sorting-associated protein 20
- Vacuolar-sorting protein SNF8
- Vacuolar protein-sorting-associated protein 24
- DOA4-independent degradation protein 4
- Vacuolar-sorting protein SNF7
Sequence:
MNNNVEELLRRIPLYNKYGKDFPQETVTRFQMPEFKLPALQPTRDLLCPWYEECDNITKVCQLHDSSNKKFDQWYKEQYLSKKPPGIVGNTLLSPSRKDNS
Protein: Zinc finger protein swm (Protein second mitotic wave missing) (Q9VIV2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Negatively regulates Hedgehog (hh) protein signal in wing development. Regulates neural-specific glycosylation by binding to FucTA mRNA and facilitating its nuclear export in neural cells.
Subcellular location: Nucleus {ECO:0000269|PubMed:18245841}.
Interaction partners:
- Polyadenylate-binding protein 2
- Probable ATP-dependent RNA helicase pitchoune
- Zinc finger CCCH domain-containing protein 3
- LD11307p
Sequence:
MILENSDKLKDWLSVVLEPLCDADSSALARYVIALLKKDKSDKDLKRIMIEQLDVFLSEETTRFVERLFDAIASEEYLTVPAAPLITASSASTAELTVDQELALVIDGPQDDIEAVLVADSPPPPPKDNVIKPDSNQVKLEQASQDAREAEALAFISQEAGIAMHVPTDAKPAFDHKTKDSHNQQSASNYQHHHVRSASPPGRSSGVSGSGGGGPGGAGLAAGYADKENQPRDSRRRRASLRSRSRSRSRSNERAFRRSRSRDRRVNEREKTQRQFRNKSPPGSQTDNRHHGRRNFDRRRIGGNADDRPRFGNNKSRRSHSRSMSPERNARRNQNSPDRVQTAQANLIPAPVAPPAPVEHPASHPRQRCRDFDEKGYCVRGETCPWDHGVNPVVFEGINNTSLMMSMREYNPDAPEIWARSGGPPPGAGQGPVPPPTQPGQTTINPFSGNVRPTTLMSGSGPSPMGVPNPADYARNPGAPPQAAMMPFPFNPTAVTTPLQRQLIPIPVVDGAPTGGVAEVGKRRFELEDTVAIADVPTKRKVPINSRLGPRVNPNMQQHNSSLELRKVPRGLNTIAHLNNHFAKFGKIVNIQVSYEGDPEAAIVTFSTHAEANVAYRSTEAVLNNRFIKVFWHNDSSGADVGQMNQMGGGGGGGGRKNASQYHLHNVPAVPTPNADGAKISNANPLTEAGAGNIGTPATEQANTAAPASMRLKLNTTTAGGSAGGAAGAGAPGSGRPLNPAANAASIRKKQEEQQKAVHQLANGLRKRKQELLQSYMKQMKTALELVERMDQQDPQRAPTLQTIKVLQMTIDKLRKEIKADQDQLQAQMQQQQQQQQPPVKKTKEQQKKELLDMELELIAQQQEGNDTTAIQKRLEELQRNLGVGSAANNKSTHYAPASGAPGGGAGRKRPNLPEGPTRVDRRPKAIVVTGFAAEEADFVLGHFKNFGEISKHDVDREIPQLILSYATRLNAEQAVLRGKMYKDKRLQISWAPVVTPAPAPMAAPVEKSAAPGDMSVSLENPKQLIQSVSESESLLGSDTLPELRLEDEEEDEESEDRSWRR
Protein: N-acetyldiaminopimelate deacetylase (EC 3.5.1.47) (D5E0A1)
Organism: Priestia megaterium (strain ATCC 12872 / QMB1551) (Bacillus megaterium)
Function: Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
Interaction partners:
- Diaminopimelate epimerase
- Aminotransferase
- Putative dipeptidase
- 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase
Sequence:
MAENEFVKIRRELHKIPELGFQEVKTQRFLLDYINTLPQERLEVKTWKTGLFVKVHGTNPTKTIGYRADIDGLPITEETNYSFQSQHEGLMHACGHDMHMAIGLGVLTYFAQHEIKDNVLFIFQPAEEGPGGAQPMLQSDIMKEWLPDFIFALHVAPEYPVGSIALKEGLLFANTSELFIDLKGKGGHAAYPHTTNDMVVAACQLVSQLQTIVARNVDPLDSAVITVGKIQGGTVQNIIAERARIEGTIRTLSPESMTRVKERIEAIVKGVEVGYQCETAIDYGCMYHQVYNHHEVTREFMEFAKEQTDVDVIECKEAMTGEDFGYMLKDIPGFMFWLGVQSEYGLHHAKLQPHEGAIDIAISLITKYFEHKGNQ
Protein: Shewanella-like protein phosphatase 2 (AtSLP2) (EC 3.1.-.-) (Q944L7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Shows phosphatase activity, hydrolyzing the artificial substrate para-nitrophenylphosphate (pNPP) in vitro.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:21976480}.
Interaction partners:
- AT5g11000/T30N20_270
- PP2A regulatory subunit TAP46
- Mitochondrial intermembrane space import and assembly protein 40 homolog
- Exocyst subunit Exo70 family protein
- Serine/threonine-protein phosphatase 4 regulatory subunit-like protein
- At4g26810
- At3g03590
- SWIB/MDM2 domain superfamily protein
- AGAMOUS-like 67
Sequence:
MSSRENPSGICKSIPKLISSFVDTFVDYSVSGIFLPQDPSSQNEILQTRFEKPERLVAIGDLHGDLEKSREAFKIAGLIDSSDRWTGGSTMVVQVGDVLDRGGEELKILYFLEKLKREAERAGGKILTMNGNHEIMNIEGDFRYVTKKGLEEFQIWADWYCLGNKMKTLCSGLDKPKDPYEGIPMSFPRMRADCFEGIRARIAALRPDGPIAKRFLTKNQTVAVVGDSVFVHGGLLAEHIEYGLERINEEVRGWINGFKGGRYAPAYCRGGNSVVWLRKFSEEMAHKCDCAALEHALSTIPGVKRMIMGHTIQDAGINGVCNDKAIRIDVGMSKGCADGLPEVLEIRRDSGVRIVTSNPLYKENLYSHVAPDSKTGLGLLVPVPKQVEVKA
Protein: Dizzy isoform BII (PDZ domain-containing guanine nucleotide exchange factor, isoform B) (PDZ domain-containing guanine nucleotide exchange factor, isoform D) (B7Z025)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDPYHHIRHHYPPTSIAGTGVVVGSSTTINRPELHQKCNRGSHSSDTSSAYSGSDTMASNYASSLEAEEIDLSGLVESVVDSDEEDLAESMDSLTVRDAVRDCLEKDPAERSEEDVEVLLEFTQGLKAFTNITLAVRRALCSVMVFAVVDKAGTVVMSDGEELDSWSVLINGAVEIEHANGSREELQMGDSFGILPTMDKLYHRGVMRTKCDDCQFVCITQTDYYRIQHQGEENTRRHEDENGFVVMVTELRSIGGAGTDSAGSGGSATGASASLNMKRGHVVIRGTPERLLQQLVEENSMTDPTYVEDFLLTHRIFIQNPQEVTSKLLHWFDLEQVDAHKTQELRDRVTRVVLLWVNNHFTDFEADYEMMEFLEVFEALLERKKLLSQLRLLHIACAAKARMRSCTLTRSSRDEPLNFRIVGGYELRGVAIATGNAAVGIYISHVEPGSKAQDVGLKRGDQIHEVNGQSLDHVTSKRALEILTGTTHLSISVKSNLLGFKEIMQALEHGGGTAGSGSISAGSGSFKSVRSPRRICANDIAKLHGRSDSTTDELSSVSASNRAHMVRLSSVDMLLDQPDCAPPQTPPVSGSGNMASNFMQQLLQSVNNSSAKKSGGNSNSDQQDTKGGFMTLAPKRRLQKALAKMNLLNKQNHGSSLNDSSDTLLNDPKSKLSAVSSCSSSTQSSINGCTVSGGGRLYQSQSNPDLTSLNYDGGSDAGGNGGGRLQVNYLNAHIHRPSAASTLTTNSTQSHLLPDYPDHVLKVYKADQTCKYVLIYKETTAHEVVMLTLQEFGIHDPSSNFSLCEVSVGDGGMVKQRRLPDQLQNLAERISFAARYYLKLNDSTEPLVPDELALELVRESNVHFLHLNAYELAIQLTLQDFANFRQIESTEYVDELFELRSRYGVPMLSKFAELVNREMFWVVSEICAEHNIVRRMKIVKQFIKIARHCKECRNFNSMFAIVSGLGHGAVSRLRQTWEKLPSKYQRLFNDLQDLMDPSRNMSKYRQLVSAELLAQHPIIPFYPIVKKDLTFIHLGNDTRVDGLINFEKLRMLAKEVRLLTHMCSSPYDLLSILELKGQSPSNALFSLNQMSASQSNAAAGTVIAANAGQATIKRRKKSTAAPNPKKMFEEAQMVRRVKAYLNSLKILSDEDLLHKFSLECEPAHGSTYSGSISHGNTSHRSGGGGSISGGAGGSSGGGGGGSSSLNAGDQLSIYSHTSSSSAPNSSLSLRKRHPSSPTLSTTSSTSSTSDHQRRQMHNNGPKFGTASPQAVKKMLSLSESSKIRPHQPFVPRHGSTMAGVIPPLHHMHAAHGFSTPSPGGVVTSPATSAVANVQCTPSPSPCSHRRLASGGNIIPSRAIHERSHSDTPAPPPPLPSVDLSLESSSVTTFRDLPLRKSVTSGSISSCDSGYVHQQQHYHLQYQQQQQQNSSQHEPSPPVYTAADCRLLQQISNNAVTRNLNSPCQSTNTPPSTPTPPPNQPTATIQLSAPPTAAAYMHARSQHQQLQQQQQSLAMPPPPPPPYNVPPLGSIYSHHQGTAGSRHLNHMHGGPPNFMDSTKCTICPMPPMNQ
Protein: LD05335p (Zinc transporter 41F, isoform A) (Zinc transporter 41F, isoform B) (Zinc transporter 41F, isoform C) (Zinc transporter 41F, isoform D) (Q8T0G1)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- IP18018p
- Proton-coupled zinc antiporter SLC30A9, mitochondrial
- FI23527p1
- Zinc/iron regulated transporter-related protein 42C.2
- P-type Cu
- FI24038p1
Sequence:
MPKYQKLDNTLLPNAHDDDSEGGFPGYFDDNHQSLGIQQDPDTRDDRLSDYQDRYYSVNNNSVNREVVTIGSNVVRVPEEQTWEVPLLGDCGDSARNQSSETEFDMQRECCNHQPGFRANSKSKSAQEAKYKIMLAVALCCVFMIIEFLGGYVAGSLAIMTDAAHLASDCISFVIGLVAIWIGGRPPDERMSFGYKRFEVIGALASILGIWFVTTLLVVVAIERIFSQDFELNADMMMLISGIGIVINIVMMFVLHGSWFVNGNGHGHSHSHSHSHSHSHGNGHEPNDSLSQTRSNSNFLTTIGSQSASTADEEDSIRKEINSNEHKIVITNGKKPTLTGTSNMELAHEDKNLNLRAAMIHVIGDLVQSIGVFLAAVLIKVCPGAKYADPLCTLIFSIIVIMTTLRLFRESLGIIVNAVPQNLNMRTLHLELGSIEGVRSLHHLNVWQQTSQQRVLMVHLVTDSRADGNEVLQAATALVSSPRYNIKHSTIQLEPTTE
Protein: MinK-related peptide, potassium channel accessory subunit protein 4 (P34394)
Organism: Caenorhabditis elegans
Interaction partners:
- BTB domain-containing protein
- MAM domain-containing protein
- BTB domain-containing protein
- MPS-3
- MiRP K channel accessory Subunit
Sequence:
MTFPKENINNYASSSFNYKYLIEEFLQWSSSCNRISYPTKYFDFLLVIIMTFVFLCLVYLLIWIEVLLNSSRPDPKHRVYYPRTNFWQRTD