wanglab/gogpt-training-data huggingface dataset:
Protein: C3H1-type domain-containing protein (Q57ZJ1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPGCLSALASHVESASVVSTKSKRKRKSKKKALYDQYLADSGSEDSSELSKNVNGTPSKYEYEEFEPGMDINILIQQTIQNVVQSVCLEDCDGLSQFGDNDLICFSAAVKHNSSILSLQIRYLDVSDVSLVPLCRALECHPSIRALDLSGTRGGRPSVKAVFQLVCTNPNILFVRLDDTMVSPHDAEDIRVATLYNALACPDPTNNPFYLGLLRKISDIEEEKQKYKEQLSEQLWLFSSRPQNNLNSGKEKKVGFSEKVSESRIGADVCAQFMSGRCAYGSRCRYIHPDKTTALRNAIALSKYKMAQMIDDDAKSVKSSATSLGQTGRGRLQSRLRPTNFTMNKVHCAVATVHEGSVEQCSAGSNEEAADVALRLSIWTFALVTAVCSVVLIVVY
Protein: DNA-directed RNA polymerase, RBP11-like protein (F4J5R0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MNAPERYERFVVPEGTKKVSYDRDTKIINAASFTVEREDHTIGNIVRMQLHRDENVLFAGYQLPHPLKYKIIVRDPKDWFRNLKVVYGCLETVNISWFKLLVLTIHTTSQSSPMQAYNQAINDLDKELDYLKNQFEAEVAKFSNQF
Protein: Dipeptide transport system permease protein DppB (P0AEF8)
Organism: Escherichia coli (strain K12)
Function: Part of the ABC transporter DppABCDF involved in dipeptide transport. Responsible for the translocation of the substrate across the membrane (Probable).
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Dipeptide-binding protein
- Dipeptide transport system permease protein DppC
- Dipeptide transport ATP-binding protein DppD
- Dipeptide transport ATP-binding protein DppF
- Oligopeptide transport system permease protein OppC
- Nickel transport system permease protein NikC
- Glutathione transport system permease protein GsiD
- Probable D,D-dipeptide transport system permease protein DdpC
- Probable ABC transporter periplasmic-binding protein SapA
- Oligopeptide transport ATP-binding protein OppD
Sequence:
MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGISPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISMKSRIPVWEEFVPRFQATLELGVCAMIFATAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHWNLTPVSGRVSDMVFLDDSNPLTGFMLIDTAIWGEDGNFIDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPRIRHKK
Protein: Riboflavin kinase (EC 2.7.1.26) (ATP:riboflavin 5'-phosphotransferase) (Flavokinase) (KOI-4) (Q8CFV9)
Organism: Mus musculus (Mouse)
Function: Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- FAD synthase
- Tartrate-resistant acid phosphatase type 5
- Flavin reductase
- Lysosomal acid phosphatase
- Ectonucleotide pyrophosphatase/phosphodiesterase family member 3
- Tumor necrosis factor receptor superfamily member 1A
- Ectonucleotide pyrophosphatase/phosphodiesterase family member 1
- NADPH oxidase 1
- Tumor necrosis factor receptor type 1-associated DEATH domain protein
- Cytochrome b-245 light chain
Sequence:
MRSLPFFCRGQVVRGFGRGSKQLGIPTANFPEQVVDNLPADVSTGIYYGWASVGSGDVHKMVVSIGWNPYYKNVKKSMETHIIHTFKEDFYGEILNVAIVGYLRPEKNFDSLESLISAIQGDIEEAKKQLDLPEHLKLKDDNFFQVSKGKIMNGH
Protein: Stress-induced protein KIN1 (P18612)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein COLD-REGULATED 15A, chloroplastic
- Dehydrin ERD10
- Low-temperature-induced 78 kDa protein
- Late embryogenesis abundant protein
- Transmembrane protein
- Protein ORGAN SIZE RELATED 1
- CAP superfamily protein
- Dehydrin Rab18
- Protein COLD-REGULATED 15B, chloroplastic
Sequence:
MSETNKNAFQAGQTAGKAEEKSNVLLDKAKDAAAGAGAGAQQAGKSVSDAAAGGVNFVKDKTGLNK
Protein: GTP:AMP phosphotransferase AK3, mitochondrial (EC 2.7.4.10) (Adenylate kinase 3) (AK 3) (F1R4S7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Mitochondrion matrix {ECO:0000256|ARBA:ARBA00004305, ECO:0000256|HAMAP-Rule:MF_03169}.
Interaction partners:
- Adenine phosphoribosyltransferase.
- Ribonucleoside-diphosphate reductase large subunit
- Adenylate kinase 9
- Nucleoside diphosphate kinase.
- Adenylosuccinate lyase
- Phosphodiesterase.
- Nucleoside diphosphate kinase
- Nucleoside diphosphate kinase 3
- Nucleoside diphosphate kinase
- Adenosine kinase
Sequence:
MGLQSVFRAVIMGAPGSGKGTVSSRIAQSFGLKHLSSGDMLRANIEAKTDLGLLMKSCIDQGQLVPDDVISRLILSSLRGLEKTSWLLDGFPRTVAQAEALDCVYDVDSVINLDVPFQTIRERLTSRWVHLPSGRVYNIDFNPPKKPGLDDVTGEPLVQRDDDSPETVSRRLKDYERQTQPVLEYYRSKGVLETFSGTETNKIWPHVHTFLSRKIPGHKQAMGKA
Protein: Protein ELC (AtELC) (ESCRT-I complex subunit VPS23 homolog 1) (Protein VACUOLAR PROTEIN SORTING 23A) (Vacuolar protein-sorting-associated protein 23 homolog 1) (Q9LHG8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). May control nuclear division through the microtubule cytoskeleton.
Subcellular location: Early endosome {ECO:0000269|PubMed:17090720}. Late endosome {ECO:0000269|PubMed:17090720}. Prevacuolar compartment {ECO:0000269|PubMed:25438943}.
Interaction partners:
- Vacuolar protein sorting-associated protein 28 homolog 1
- Vacuolar protein-sorting-associated protein 37 homolog 1
- Vacuolar protein-sorting-associated protein 37 homolog 2
- Vacuolar protein sorting-associated protein 28 homolog 2
- Vacuolar protein sorting-associated protein 36
- Protein FREE1
- Vacuolar protein sorting-associated protein 32 homolog 1
- Vacuolar protein sorting-associated protein 24 homolog 1
- Putative vacuolar protein sorting-associated protein 24 homolog 2
- Vacuolar protein sorting-associated protein 32 homolog 2
Sequence:
MVPPPSNPQQVQQFLSSALSQRGPSSVPYEESNKWLIRQHLLNLISSYPSLEPKTASFMHNDGRSVNLLQADGTIPMPFHGVTYNIPVIIWLLESYPRHPPCVYVNPTADMIIKRPHAHVTPSGLVSLPYLQNWVYPSSNLVDLVSDLSAAFARDPPLYSRRRPQPPPPSPPTVYDSSLSRPPSADQSLPRPFPPSPYGGGVSRVQVQHVHHQQQSDDAAEVFKRNAINKMVEMVHSDLVSMRRAREAEAEELLSLQAGLKRREDELNIGLKEMVEEKETLEQQLQIISMNTDILDSWVRENQGKTKNLVDLDVDNAFECGDTLSKQMLECTALDLAIEDAIYSLDKSFQDGVVPFDQYLRNVRLLSREQFFHRATGSKVRAAQMEVQVAAIAGRLHS
Protein: Protein RETICULATA-RELATED 5, chloroplastic (Q9SIY5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May play a role in leaf development.
Subcellular location: Plastid, chloroplast membrane {ECO:0000250|UniProtKB:Q9C9Z2}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MKPTTNGGLLASQSSSSFSFPRFRGQLPIIFSANNNQKKKNLPNPNVVTLCLHSHSNVSSSQIAVTRRAILVAPPLLAAAASLFLSISSAASAETSAESVALPPVATAPPPPPVEKEEAITSRIYDASVLGEPMAVGKDKKRVWEKLLNARIVYLGEAEQVPTRDDKVLELEIVRNLRKRCIESDRQLSLALEAFPLDLQEQLNQYMDKRMDGEVLKSYVSHWPVQRWQEYEPLLSYCRDNGVKLIACGTPLKVLRTVQAEGIRGLSESERKLYTPPAGSGFISGFTSFSRSSSLNMNPLTQIVPFGPSSYLSAQARVVEDHTMSQVIVQAVADGGGTGMLVVVTGANHVEYGSRGTGLPARISRKIPKKSQLVVLLDPERQFLRKEGESPVADFLWYSAARPCSRNCFDRAEIARVMNAAGRRRDALPQDIQKGLDLGLVSPEILQNFFDLEQYPLISELTQRFQGFRERLLADPKFLNRLAIEEAISITTTLVAQYEKRKENFFEELDYVITDSVRASVVDFFTVWLPAPTLSFISYADETIGPNSIDALRGLLGSIPDNAFQKSLGGQEWTLSLRIASVIIGGLKLAGVGVVSSFAAVGSSNALYAIRKFIKPELGVGEQAKRSPMLKTALVYGGYLGTSSNIRYQIIAGLIEHRISDELSSQPLLVNMISFVVRVANSYFGTQQWIDLARSTGLQTQKSVTTSNQIPEVASQSTVEYSTTEEASMDDLKNQ
Protein: Regulatory-associated protein of TOR 2 (Protein RAPTOR 1A) (AtRaptor1a) (Protein RAPTOR 2) (Q9LZW9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable component of the plant TOR kinase pathway.
Interaction partners:
- Serine/threonine-protein kinase TOR
- Target of rapamycin complex subunit LST8-1
- Non-functional target of rapamycin complex subunit LST8-2
- PP2A regulatory subunit TAP46
- Probable ethanolamine kinase
- Serine/threonine-protein kinase AtPK1/AtPK6
- Peptidyl-prolyl cis-trans isomerase FKBP12
- Autophagy-related protein 11
- Autophagy-related protein 101
- Uncharacterized protein
Sequence:
MALGDLMVSRLSQSSVTVVTNHLYDDDDNCASSAHDDSRVSIIASPRVASSSYENLSAATSMAYLPQTLVLCDLRHDDASDIVQPPRWRLKERMKTGCVALVMCLHITVDPPDVIKISPCARLECWIDPFSMFPPRRALEAIGQNLSIQYERWLARARYKVELDPTKDDVRKLCLSCRKYAKTERVLFHYNGHGVPKPTPNGEIWVYNKNFTQYIPLPVSELDSWLKTPTIYVFDCSAARVILNAFAEGESSGPPKDCILLAACDVHETLPQSVEFPADVFTSCLTTPINIALKWFCRRSLLKEFIDESLIDRIPGRQNDRKTLLGELNWIFTAVTDTIAWNVLPRELFQRLFRQDLLVASLFRNFLLAERIMRSGNCTPISHPMLPPTHQHHMWDAWDMAAEICLSQLPQFFLDPNTEFQPSSFFTEQLTAFEVWLDHGSEHKKPPEQLPIVLQVLLSQCHRYRALVLLGRFLDMGPWAVDLALSVGIYPCVVKLLQTTTIELRQILVFIWTKILALDKSCQVDLVKDRGHIYFIRFLDSSDAFPEQRAMAAFILAVIVDGYKRGQESCLEANLIAVCLGHLEATQLCDPPPEPLFLQWLCLCLGKLWEDYLEAQIMGREANASENLIAGHTNLLQVRAAAVFALGTLLDVGFDSGKGVCDEEFDDDENIVEDIIIKSLLDVVSDGSPLVRTEVAVALARFAFGHKQHLKSVADSYWKPQNSLRTSLPSMAKFHDSGTSIVASSDMGSLTRASPDSQPVAREGRISSSLQEPFSGLMQGSPLADDSSLHSDVGIIHDGVSNGVVHQPRPLDNAIYSQSVLAMFTLAKDPSPRIASLGRRVLSVIGIEQIVAKPSKSNGRPGEAASASHTPLAGLVRSSSWFDMHTGHLPLTFRTPPVSPPQTSYLTGLRRVCSLELRPHLLGSPDSGLADPILGVSGSERSLLPQSTIYNWSCGHFSKPLLGGADANEEIAAQREEKKKFSLEHIAKCQHSSISGLSNIPIANWDTKFETGTKTALLHPFSPIVVAADENERIRVWNYEEATLLNGFDNNDFPDKGISNLCLVNELDDSLLLVASCNVPTLSRASFAIRIWKDYATKGRQKLVTGFSSIQGQKPGASGLNAVVDWQQQSGYLYVSGESLSIMVWDLDKEQLVKSMPFESGCSVTALSASQVHGSQLAAGFADGSVRLYDVRTPDFLVCATRPHQRVEKVVGLSFQPGLDPAKIVSASQAGDIQFLDLRRPKETYLTIDAHRGSLTALGVHRHAPIIASGSAKQLIKVFSLKGEQLGIIKYHTSFMGQQIGPVSCLAFHPYQMLLAAGAAGSFVSLYTHHNTQLPR
Protein: E3 ubiquitin-protein ligase (EC 2.3.2.26) (K7WBL1)
Organism: Artemia sinica
Interaction partners:
Sequence:
MTQGVHPNIYQLKVTVEYVNLNQEHVSKKPNAYVEIVVDKKHTRKTESVKGDHNPRWNETLTILVTPYSKIHMRLLHHSLFRRDTLIGETDLDLYPLLQSKDGKLSLLQKCFNLEGSSMSRNSRTTFGNLFVVLDGINIDMSLVPEPPRYSQNSNSGGEIVRRNSLPNRPIPNGTASGEGSIQVRTHRSRRSDATASAVQAAVGPSLSAPSHSVGDVNRAGPSSQSPANRPVLLTAPPSIVNPNSSEPVGNGVIPLPNMAVASSTTAITSSVAAGDSNPISPPSEEPLPQGWEMRYDKYGRKYYVDHSTRTTTWERPQPLPPGWEMRFDNRGRAYYVDHNTRSTTWQRPTTQRLQDFQHWQGQRGHIVTQGNQRFLYPQGSGAAEDEDPLPEGWEKRTETNGRVYFVNHKNRTTQWEDPRTQGQIQEEALPDGWEMRLTEDGVRYFVDHVSKNTTFEDPRPNAARGLKGAYGVPQAYERSFRWKLSQFRYLCTSNALPSHIKLTVSRQTLFEDSFHQIMRLPAYELRRRLYIIFRGEEGLDYGGVAREWFLLLSHEVLNPMYCLFEYANKSNYSLQINPASHVNPDHLHYFKFIGRFIAMALYHGKFIYSGFTLPFYKRMLNKKLNVKDVESIDPEFHNSIVWIRENNIEEVGLELYFSADFEVLGQVSQHNIKEDGDQIRVTEENKEEYVMLLTEWRMTRGIEDQTRALLDGFSEVVPLEWLKYFDERELELMLVGMQEIDVEDWQKHTVYRHYTRNSKQVQWFWQFMKAMDNEKRARLLQFVCGTCRVPVGGFAELMGSNGPQRFCIERVGKETWLPKSHTCFNRLDLPPYRSYEQLVEKLTYAIEETEGFGQE
Protein: Taurine import ATP-binding protein TauB (EC 7.6.2.7) (Q47538)
Organism: Escherichia coli (strain K12)
Function: Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_01714}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01714}.
Interaction partners:
- Taurine transport system permease protein TauC
- Taurine-binding periplasmic protein
- Alpha-ketoglutarate-dependent taurine dioxygenase
- Putative aliphatic sulfonates transport permease protein SsuC
- Nickel import ATP-binding protein NikD
- Probable D,D-dipeptide transport ATP-binding protein DdpD
- Putrescine export system ATP-binding protein SapD
- Putative aliphatic sulfonates-binding protein
- Molybdenum transport system permease protein ModB
- Aliphatic sulfonates import ATP-binding protein SsuB
Sequence:
MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSIQLAGKRIEGPGAERGVVFQNEGLLPWRNVQDNVAFGLQLAGIEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTRDQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSSGPGRVLERLPLNFARRFVAGESSRSIKSDPQFIAMREYVLSRVFEQREAFS
Protein: Phloretin hydrolase (EC 3.7.1.4) (Q715L4)
Organism: Eubacterium ramulus
Function: Catalyzes the hydrolytic C-C cleavage of phloretin to phloroglucinol and 3-(4-hydroxyphenyl)propionic acid during flavonoid degradation. Also hydrolyzes other C-acylated phenols.
Subcellular location: Cytoplasm {ECO:0000305|PubMed:15466559}.
Interaction partners:
- NADPH-dependent FMN reductase
- Flavodoxin family protein
Sequence:
MEEDFNMSTPGVKVGVXEEEKKLSYYKYYEQDLAPVPAEKIAILQGGPIAPEKCIPFDERNKFLKGEDDEYANIGFGVAADGTALVCNTTYMPGVTGEMLDWWFPWHSVGSDLRYKIWDPEDHYFARAYPASYVVDPNVPMNQKTWGVDHYIMEDVGPGPEFLKLCFKRPADFGYDESIIGTEKCESLVCAIGESSCAAAMTHKWHPYKDGVLFESRFWIGYRIDEEGNIVKAIPEGVSIPPFVPQGLFAHNIKEFTNLAAILPTLYAEEKDTF
Protein: Tyrosine kinase Ret isoform 1 (Tyrosine kinase Ret isoform 2) (Q9BHA9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MESTTIVFVTLLTIITQRKHCAAVDVYFPTTSVKFNLPINEESESIFSKIPLAQFQVLRMEDNRLASDYLYSLEQNPLLRINSSPGEIYMRTDYRSPNSSATFLVTAFPRDQPDHELLNVSHLSLEVTPQPLEEYCSELEHICFWSSAQYTIAESHGPYRRKDFFEPVLIGALNSRAAKYLCPHVSLEYSLNAGSSHFVLKQNRLYTRQTLDHDELNGLNAKAGQLQARITCTVKLSSRDQRKFSRILDIKLLDRNDNGPKLQESSSKFDFYLEQPYFQADEEAGKNVIYVDKDTLEANAHLVYAVHNDSHGLFRPDCHAYEADHTGRPHTIVSCQLRFSRNGVFRETPYCVSLEARDLTIVSRVDAMSATANVCYHINLSKLHESEQELPQALPLRARQHRIFESEEFNGDSAGRSLSPPTVDYDKDVSVYRSAASNFRVVQPDSFLDLMRLRSIRFDIVEDKLGAFGITSTSGIVFVKNPQVLEEAPETIYFLNVTWIDQQRLSHVRVINVHLVHGRPENTSCELKVKSRSQTCAQIKYQSQCVRYCGLATGGGSCQWRGSNSAMFGTRYGSCVPESRYCPDHVCDPLEELNPMACPQDCTPAGRIVGPHSSNENKRGIYSASGTCICEDNGKCSCAPLDEEPKMKKPRKRKNETEAEPLLGVRRGTPPNQPLQDPMLLGVLNAAGFECDRSCMFFVITCPLLFVLLLLCLLIAQRKMLQRRLGKQSMTTSSKQALPESGGGDFALMPLQSGFRFESGDAKWEFPREKLQLDTVLGEGEFGQVLKGFATEIAGLPGITTVAVKMLKKGSNSVEYMALLSEFQLLQEVSHPNVIKLLGACTSSEAPLLIIEYARYGSLRSYLRLSRKIECAGVDFADGVEPVNVKMVLTFAWQICKGMAYLSELKLVHRDLAARNVLLADGKICKISDFGLTRDVYEDDAYLKRSRDRVPVKWMAPESLADHVYTSKSDVWSFGVLCWELITLGASPYPGIAPQNLWSLLKTGYRMDRPENCSEAVYSIVRTCWADEPNGRPSFKFLASEFEKLLGNNAKYIDLETNAVSNPLYCGDDSALITTELGEPESLQHLWSPPKIAYDIHDQATSYDQSEEEMPVTSTAPPGYDLPRPLLDATANGQVLRYENDLRFPLNIRKSSCTPSYSNMTSEPPATTSLPHYSVPVKRGRSYLDMTNKSLIPDNLDSREFEKHLSKTISFRFSSLLNLSETKEVSPGWQAEDAV
Protein: glutathione transferase (EC 2.5.1.18) (C8BLR1)
Organism: Meleagris gallopavo (Wild turkey)
Interaction partners:
Sequence:
MSGKPVLHYPNSRGRMESVRWLLAAAGVEFEEKFLEKKEDLQKLQSDGSLLFQQVPMVEIDGMKLVQTRAILNYIAGKYNLYGKDVKERALIDMYVEGMADLYELIMMNVVQPADKKEEHLANALDKATNRYFPVFEKILNHGHDFLVGNKLSRADVSLLETILVVEERKPDALAKFPLLQSFKARISNTPNIKKFLQPGSQRKPPLQEKDIPSLMAIFH
Protein: U1 small nuclear ribonucleoprotein 70 kDa (A0A8I6G5W4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKDERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDGAPDDGPPGELGPEGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDREHKRGERGSERGRDEARGGGGSGQDNGLEGLGSDGRDMYMEAEGGDGYMAPENGYLMEAAPE
Protein: Translation initiation factor IF-2, mitochondrial (IF-2(Mt)) (IF-2Mt) (IF2(mt)) (Q91YJ5)
Organism: Mus musculus (Mouse)
Function: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity).
Subcellular location: Mitochondrion {ECO:0000250}.
Interaction partners:
- Ubiquitin-like protein FUBI
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS19
- Large ribosomal subunit protein uL18
- Elongation factor Ts, mitochondrial
- Small ribosomal subunit protein uS17
- Large ribosomal subunit protein uL23
- Large ribosomal subunit protein uL5
- Small ribosomal subunit protein uS9m
- Large ribosomal subunit protein bL9m
Sequence:
MNQKLLKLENLLRFHTICRQVHSPSQRRLLAWCRHGFAPASSVWRDLLGARSWQTDMLIGSALHQHRLLVTKKEKRPPRSQLSPVKTKKEVEVWVGMTVEDLASAMAKDIDCVYEALLNTAIDVDSLEANSHLDEVWIKEVIKKAGMKLKWSKLKQERIRENKDAVRRPGTDPALLKPRSPVVTVMGHVDHGKTTLLDKLRETQVAAMEVGGITQHIGAFLVSLPSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAEVPIILAINKCDKTDADPEKVKKELLAYDVVCEEYGGDVQAVHVSALTGDNLMALAEATIALAEILELKADPTGPVEGTVIESFTDKGRGPVTTAIIQRGTLRKGSILVAGKSWAKVRLIFDENGKILNEAYPSMPVGIIGWRDLPSAGDEILEVESEPRAREVIEWRKSEQKEEKGKDDLKIMEEKRREHQEAHRKAREKYGSLHWKERSYIKFLERKQQRPLKPKEKVERQSNVLPIIIKGDVDGSVEAILNLLDTYDASHECELELVHFGLGDISENDVTFAETFDGVIYGFNVEAGSAIQQSAAQKGVKIKLHKIIYHLIEDLQEELSSRLPHTLEEYPIGEASILATFTVTEGKKKIPVAGCRVQKGQLERHKKFKLIRNGQVIWKGSLTSLKHHKDDISVIKTGMDCGLSLDEEKVEFKPGDQVICYEENKVPTKTSWDPGF
Protein: ATP-dependent 6-phosphofructokinase (ATP-PFK) (Phosphofructokinase) (EC 2.7.1.11) (Phosphohexokinase) (Q5AK53)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03184}.
Interaction partners:
- ATP-dependent 6-phosphofructokinase
- Glucose-6-phosphate isomerase
- Hexokinase-2
- Fructose-bisphosphate aldolase
- Phosphotransferase
- Phosphotransferase
- N-acetylglucosamine kinase 1
- Pyruvate kinase
- fructose-bisphosphatase
- Transketolase
Sequence:
MPSSSDAINRISYISLVTSDNDKFNQTFQFYSQLGFRLTKSFSKVSSYGSGLGANHPEFQLGVSHDSLKEVWLESYPLQNVDSNGNLRPWQEMEVYDGDNCERLNESTVIKVRLLGETPLKSISQKQFVFFTTQLNKIEKILTDANVKYGKVVDNVILAEDPLSNIISFSNTQNELCKTRFQSPEEYVEKTTAEILAKRKKSQLGSKFGSFEEISPSEVGGGNGLRKKKIGVMTSGGDAPGMNPAVRAVVRAGIYYGCDVYAVYEGYEGLVKGGDLLKKMEWSDVRSYMSLGGTSIGTARCKEFRERAGRLQGAYNMIKNGIDALVVCGGDGSLTGADLFRSEWPSLVKELVDTGKLTKEEVSPYEHLTIVGLVGSIDNDMSGTDVTIGAFSALERITEMVDYIGATAASHSRAFVVEVMGRHCGWLALLSGLATGADFVFIPERPPKAGLWKEQLKEVCLRHREYGRRKTTVIVAEGAIDDELNPITSEEVKQVLADLGLDTRNTILGHVQRGGTAVAFDRRLATLQGVEAVKAVLEMTPDTPSPMIGILKHKIVRIPLVDAVKQTKAVAEAISNKDFDKAMSLRDNSFYDDYRYFRDISIYDDGSKQLSEDKRLNIAIVHVGAASAGLNAATRAVALYSLSRGHKLYAVQDGFAGLVKGDLKNLTWMDVEGWHSLGGSEIGTNRSLPSQNIGKVAYNLQKFNIQGLLIVGGFEAFTSLHELSEQKANYPIFEIPMVVVPATVSNNVPGTEYSLGADTCLNQLVSYCDAVQQSASSTRRRVFVVEVQGGHSGYVASYCGLITGALATYTPESNINLRELQGDIDLLQKVFATDRGEDHNGTLIVRNEQASAVYSTQLIADILKENANKRFETRTAIPGHVQQGFTPSANDRVMAVKFSLKAMEFIETRNGCYGKHDRKFSDEEISEHSQVVIGIHGDVVKFTCIKHLYDNEANVALRKGKTVHWTDMIDVANILNGKSLLKKQERY
Protein: E3 ubiquitin-protein ligase Os04g0590900 (EC 2.3.2.27) (RING-H2 finger protein Os04g0590900) (RING-type E3 ubiquitin transferase Os04g0590900) (Q7XLY8)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Possesses E3 ubiquitin-protein ligase in vitro.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MASSAPAWVPYEPTRDCSQGLCSMYCPQWCYFIFPPPPPFDVAGTSADDSSGPVFSPLVIAIIGVLASAFLLVSYYTFISKYCGTVSSLRGRVFGSSSGGAAYGGGAGSGGRHGHGQSRSHESWNVSPPSGLDETLINKITVCKYRRGDGFVHTTDCSVCLGEFSDGESLRLLPRCSHAFHQQCIDTWLKSHSNCPLCRANITFVTVGLASPEPEGCAPGETGGDNTHEVVVVMDGLENLCEEQQEAVSRASTADDDHDAKDVAEGMEEANGAAEIREEGSPPKRGASSFDLHRDNRMCIADVLQESMEDELTAARESGLLAGGAGTSRRCHGENSKGRGGRSRRALQLQDAMEALPGKRLPSGGRSCFSSKSGRGKDSDHPM
Protein: Translation initiation factor eIF2 assembly protein (Cell division cycle protein 123 homolog) (Protein D123) (HT-1080) (PZ32) (O75794)
Organism: Homo sapiens (Human)
Function: Required for S phase entry of the cell cycle.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q62834}.
Interaction partners:
- Eukaryotic translation initiation factor 2 subunit 3
- Calcium/calmodulin-dependent protein kinase type 1D
- Eukaryotic translation initiation factor 2 subunit 2
- Juxtaposed with another zinc finger protein 1
- Threonylcarbamoyladenosine tRNA methylthiotransferase
- ADP-sugar pyrophosphatase
- Proton-coupled zinc antiporter SLC30A8
- A disintegrin and metalloproteinase with thrombospondin motifs 9
- Tetraspanin-8
- Hematopoietically-expressed homeobox protein HHEX
Sequence:
MKKEHVLHCQFSAWYPFFRGVTIKSVILPLPQNVKDYLLDDGTLVVSGRDDPPTHSQPDSDDEAEEIQWSDDENTATLTAPEFPEFATKVQEAINSLGGSVFPKLNWSAPRDAYWIAMNSSLKCKTLSDIFLLFKSSDFITRDFTQPFIHCTDDSPDPCIEYELVLRKWCELIPGAEFRCFVKENKLIGISQRDYTQYYDHISKQKEEIRRCIQDFFKKHIQYKFLDEDFVFDIYRDSRGKVWLIDFNPFGEVTDSLLFTWEELISENNLNGDFSEVDAQEQDSPAFRCTNSEVTVQPSPYLSYRLPKDFVDLSTGEDAHKLIDFLKLKRNQQEDD
Protein: Nuclear protein localization protein 4 homolog 1 (H2KYU6)
Organism: Caenorhabditis elegans
Function: In association with ufd-1 and ATPase cdc-48.1 and/or cdc-48.2, involved in the cytoplasmic elimination of misfolded proteins exported from the ER. This pathway, known as ERAD, prevents the activation of the unfolded protein response (UPR) caused by the accumulation of misfolded proteins in the ER. During S phase and in association with ufd-1, cdc-48.1 and/or cdc-48.2 and ubxn-3, ensures the degradation of DNA licensing factor cdt-1 after the initiation of DNA replication and thus the disassembly of the DNA replication CGM helicase complex by promoting the dissociation from chromatin of several of its components including cdc-45 and sld-5. Regulates ubxn-3 nuclear localization during S phase.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18728180}. Nucleus {ECO:0000269|PubMed:18728180}. Note=Localizes to the cytoplasm during mitosis. Nuclear localization upon nuclear membrane re-assembly is cdc-48-dependent. {ECO:0000269|PubMed:18728180}.
Interaction partners:
- Ubiquitin fusion degradation protein 1 homolog
- Transitional endoplasmic reticulum ATPase homolog 1
- Transitional endoplasmic reticulum ATPase homolog 2
- Nuclear protein localization protein 4 homolog 2
- ATPase family protein 2 homolog
- Ubiquitin fusion degradation protein 3 homolog
- Ubiquitin conjugation factor E4 ufd-2
- Derlin-2
- Derlin-1
- Ubiquitin-ribosomal protein eL40 fusion protein
Sequence:
MVLEVPQTERVNDVDVFLSTQDGQIQRPKGPNCRHPVRQKCTNCLPVDPFDEEYLKEKDIKHMSFHAHVRKLLGSQGKGTTLKKPLENFRCSLKPNCDAHKPFPKGICTKCKPQVVTLNRQKFRHVDNIQIENQELVNQFLDYWRLSGHQRVGFLIGQYQPHLEVPLGIKATVAAIYEPPQHCREDGIEFLEDKNQKTIDNLLEMLGLQRVGWIFTDCWTANSAEGTVHYTRHKDSFFLSAEECITAAMLQNQHPNITEYSMDRHYGSKFVTVVASGDESMHVNFHGYQVSNQCAAMVEADILCPTLYTPELAYVRETPLSEEHYITDVQFSMKNEYGAEVMKNGRPLPVEYLLVDVPAGMPKEPHYTFHVGTSNKSKSAKFNVENRQAIGQLQGGANLIQYSSEFSKNQFLEQATNFHFLLYLVTNDQVQISDEWMKRLCDAVKAQDRGTAMEWAQECEDWHQLMALAHANGGSGNDVSDIPVIPNGDPFSGSSSGGSGGAVWNCGHCTFQNEAARQDCSMCGLPAAD
Protein: Small ribosomal subunit protein uS7m (28S ribosomal protein S7, mitochondrial) (MRP-S7) (S7mt) (Q9VKX4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q3T040}.
Interaction partners:
- Small ribosomal subunit protein uS15m
- Small ribosomal subunit protein bS6m
- Small ribosomal subunit protein mS29
- Small ribosomal subunit protein uS12m
- 28S ribosomal protein S14
- Small ribosomal subunit protein uS2m
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein uS5m
- Mitochondrial ribosomal protein S11
Sequence:
MSLLGRIAEKTSRLSCLRLMSVYPTHYVEPIVQKYKQLEQKNDLSKLYHVPIKAAVNKSSDTIFHDDTKHKMINYITKKGNSALARTLLSKTLELIKRTQTEHMNLAKGEKTTINTNPETLLKQAVENCRPLLQVTAIKRGGVTYQVPVPITTKRSYFLAMKWLLEAAREKERKVSLPEKLAWEILDAAHGQGRVIKRKDDLHRLCESNRAYAHYRWS