wanglab/gogpt-training-data huggingface dataset:
Protein: Vacuolar protein sorting-associated protein 35C (Vesicle protein sorting 35C) (A8R7K9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport. Also involved in the efficient sorting of seed storage proteins (By similarity). The VPS29-VPS26-VPS35 subcomplex may be involved in recycling of specific cargos from endosome to the plasma membrane.
Subcellular location: Cytoplasm. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Prevacuolar compartment membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Interaction partners:
- Vacuolar protein sorting-associated protein 29
- Vacuolar protein sorting-associated protein 26A
- Vacuolar protein sorting-associated protein 26B
- Sorting nexin 2B
- Sorting nexin 2A
- Sorting nexin 1
- Vacuolar protein sorting-associated protein 35B
- Vacuolar protein sorting-associated protein 35A
- Uncharacterized protein At5g48340
- DCD
Sequence:
MIADDDEKWLAAAIAAVKQNAFYMQRAIDSNNLKDALKFSAQMLSELRTSKLSPHKYYELYMRVFNELGTLEIFFKEETGRGCSIAELYELVQHAGNILPRLYLLCTIGSVYIKSKDVTATDILKDLVEMCRAVQHPLRGLFLRSYLAQVTRDKLPSIGSDLEGDGDAHMNALEFVLQNFTEMNKLWVRMQHQGPSREKEKREKERNELRDLVGKNLHVLSQLEGVDLGIYRDTVLPRILEQVVNCKDELAQCYLMDCIIQVFPDDFHLQTLDVLLGACPQLQPSVDIKTVLSGLMERLSNYAASSVEALPNFLQVEAFSKLNYAIGKVVEAQADLPAAASVTLYLFLLKFTLHVYSDRLDYVDQVLGSCVTQLSATGKLCDDKAAKQIVAFLSAPLEKYNNVVTILKLTNYPLVMEYLDRETNKAMAIILVQSVFKNNTHIATADEVDALFELAKGLMKDFDGTIDDEIDEEDFQEEQNLVARLVNKLYIDDPEEMSKIIFTVRKHIVAGGPKRLPLTIPPLVFSALKLIRRLRGGDENPFGDDASATPKRILQLLSETVEVLSDVSAPDLALRLYLQCAQAANNCELETVAYEFFTKAYLLYEEEISDSKAQVTALRLIIGTLQRMRVFNVENRDTLTHKATGYSARLLRKPDQCRAVYECAHLFWADECENLKDGERVVLCLKRAQRIADAVQQMANASRGTSSTGSVSLYVELLNKYLYFLEKGNQQVTGDTIKSLAELIKSETKKVESGAEPFINSTLRYIEFQRQQEDGGMNEKYEKIKMEWFE
Protein: Probable sodium/metabolite cotransporter BASS6, chloroplastic (Bile acid transporter 4) (Bile acid-sodium symporter family protein 6) (Q8VYY4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May function as sodium-coupled metabolite transporter across the chloroplast envelope.
Subcellular location: Membrane {ECO:0000305|PubMed:19542295}; Multi-pass membrane protein {ECO:0000305|PubMed:19542295}. Plastid, chloroplast envelope {ECO:0000305|PubMed:19542295}.
Interaction partners:
- Plastidal glycolate/glycerate translocator 1, chloroplastic
- Nucleobase-ascorbate transporter 8
- Polyketide cyclase / dehydrase and lipid transport protein
- Amino acid transporter AVT6D
- Polyadenylate-binding protein-interacting protein 9
Sequence:
MSVITTPIETLHLKSTLRLLPRAVYRSQRIQVFPPNIFSNTSLSSPLRIDPISQVGGSRNLWRRYASDNFSEMGLDPGADPFKVIEKPSIVDRMKKANSILPHVVLASTILALIYPPSFTWFTSRYFVPALGFLMFAVGINSNEKDFLEAFKRPKAILLGYVGQYLVKPVLGFIFGLAAVSLFQLPTPIGAGIMLVSCVSGAQLSNYATFLTDPALAPLSIVMTSLSTATAVLVTPMLSLLLIGKKLPVDVKGMISSILQVVIAPIAAGLLLNKLFPKVSNAIRPFLPILSVLDTACCVGAPLALNINSVMSPFGATILLLVTMFHLSAFLAGYFLTGSVFRNAPDAKAMQRTLSYETGMQSSLLALALATKFFQDPLVGIPPAISTVVMSLMGFTLVLIWSKEKSNTF
Protein: Large ribosomal subunit protein uL6x (60S ribosomal protein L9-2) (Q9SZX9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Large ribosomal subunit protein eL32z
- Large ribosomal subunit protein uL23y
- Large ribosomal subunit protein uL4y
- Large ribosomal subunit protein eL8y
- Large ribosomal subunit protein uL18y
- Large ribosomal subunit protein uL4z
- Large ribosomal subunit protein uL23z
- Large ribosomal subunit protein eL31z
- Large ribosomal subunit protein uL22y
- Large ribosomal subunit protein uL22z
Sequence:
MKTILSSETMDIPDGVAIKVNAKVIEVEGPRGKLTRDFKHLNLDFQLIKDQVTGKRQLKIDSWFGSRKTSASIRTALSHVDNLIAGVTQGFLYRMRFVYAHFPINASIDGNNKSIEIRNFLGEKKVRKVEMLDGVKIVRSEKVKDEIILEGNDIELVSRSCALINQKCHVKKKDIRKFLDGIYVSEKGKIAVEE
Protein: Zinc finger protein HVO_2753 (Small CPxCG-related zinc finger protein) (Zinc finger mu-protein HVO_2753) (Zn-ribbon RNA-binding protein) (D4GWB3)
Organism: Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)
Function: Zinc-binding protein. Binds 1 zinc ion. Required for swarming. Involved in biofilm formation.
Interaction partners:
- Elongation factor 1-beta
- Small ribosomal subunit protein eS17
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein eS27
- Small ribosomal subunit protein uS17
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein eS19
- Small ribosomal subunit protein uS2
- Small ribosomal subunit protein uS8
- Small ribosomal subunit protein uS5
Sequence:
MSESEQRHAHQCVSCGINIAGMSAATFKCPDCGQEISRCSKCRKQSNLYECPDCGFMGP
Protein: Dihydroxyacetone phosphate acyltransferase (DAP-AT) (DHAP-AT) (EC 2.3.1.42) (Acyl-CoA:dihydroxyacetonephosphateacyltransferase) (Glycerone-phosphate O-acyltransferase) (Q9ES71)
Organism: Rattus norvegicus (Rat)
Function: Dihydroxyacetonephosphate acyltransferase involved in plasmalogen biosynthesis.
Subcellular location: Peroxisome membrane {ECO:0000269|PubMed:9459311}; Peripheral membrane protein {ECO:0000269|PubMed:9459311}; Matrix side {ECO:0000269|PubMed:9459311}. Note=Exclusively localized to the lumenal side of the peroxisomal membrane. {ECO:0000269|PubMed:9459311}.
Interaction partners:
- Alkyldihydroxyacetonephosphate synthase, peroxisomal
- Glycerol-3-phosphate dehydrogenase [NAD
- Glycerol-3-phosphate dehydrogenase [NAD
- Glycerol-3-phosphate dehydrogenase, mitochondrial
- 1-acylglycerol-3-phosphate O-acyltransferase 3
- 1-acyl-sn-glycerol-3-phosphate acyltransferase
- 1-acyl-sn-glycerol-3-phosphate acyltransferase
- 1-acyl-sn-glycerol-3-phosphate acyltransferase delta
- 1-acylglycerol-3-phosphate O-acyltransferase 5
- Diacylglycerol kinase
Sequence:
MDVPSSSSSRFSVGSASPSSVLLYAKDLKKWDEFEDLLEERRQVSDFKFAMKCYTPPLYRGITPCKPSDIKSIVLNSEEINYVIKQLSRESLTGVDVLREEANEILEEMSHKLRIGAIRFFAFVLSKVFKQIFSKVCVNEEGIQKLQRAIQEHPVILLPSHRSYIDFLMLSFVLYNYDLPVPVIAAGMDFLGMRVVSELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRSGYAPVEFFLEGTRSRAAKTLTPKFGLLNIVMEPFFKREVFDTYFVPISISYDKILEESLYAYELLGIPKPKESTTGLLKARRILSENFGSIHVYFGDPVSLRSLAAGRLSRNTYNLVPRCIPQKQPEDVQAFVTEVAYKMQLLQIENLALSPWLLVVAILLQNQLCMDFDALVEKTLWLKGLTQVFGGFLLWPDNKLPEEVVQSSILLHSNLATLVKDQVVLKVDSESSQMVNGLVPQHIAFLMCSAYRNQLLNVFARPSLVAVALHMTPGLRKEDVFSCFSFLRNVFSDEFIFLPGNTLRDFEEGCYLLCKTEVMQMTGKDIILTDKGNAVLQFLTGLFKPFVESYQILSKCLLHEEDYFSEKEYLVTARKFTRQLLDQDASQCYDALSSELQKNALAAFVRLGVVEKNKVDSKYVYYVNGPATSKLEEMLGCKKPIGKPATAKL
Protein: Apolipoprotein C-III (Apo-CIII) (ApoC-III) (Apolipoprotein C3) (P33622)
Organism: Mus musculus (Mouse)
Function: Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners.
Subcellular location: Secreted {ECO:0000250|UniProtKB:P02656}.
Interaction partners:
- Apolipoprotein A-I
- Apolipoprotein C-II
- Apolipoprotein A-II
- Apolipoprotein B-100
- Apolipoprotein C-I
- Apolipoprotein E
- Apolipoprotein A-IV
- Apolipoprotein A-V
- Lipoprotein lipase
- Toll-like receptor 2
Sequence:
MQPRTLLTVALLALLASARAEEVEGSLLLGSVQGYMEQASKTVQDALSSVQESDIAVVARGWMDNHFRFLKGYWSKFTDKFTGFWDSNPEDQPTPAIES
Protein: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 (3-beta-hydroxysteroid dehydrogenase) (Q7ZZC3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MALSGEVCVVTGACGFLGEKLVRLLLEEENLSEIRLLDRNIRSELIQTLEDGRGETKVSVIEGDIRDRELLRRACKGATLVFHTASLIDYNGAVEYSELHAVNVKATRLLLETCIQQSVSSFIYTSSIEVACPNRSGEPIINGHEDTPYSSYPISNYSKTKQEAEQICLQANGELLRDGGHLATCALRPMFIYGPGCRFTLNKLRDAIRSGNVQHRLSQQSAKVNPVYVGNAALAHLQAGRALRDPEKRAVVGGNFYYVSDDTPHISYCDLTHALMSPLGFSIQNKPILPIFLLYLLAFFMEILQAVLRPVLRFTPPLNRQLVTMVNTPFSFSYQKACREFGYSPRYDWEEARRSTTDWLASVLPAERRLANKT
Protein: Protein Abitram (Actin-binding transcription modulator) (Protein Simiate) (Q80ZQ9)
Organism: Mus musculus (Mouse)
Function: Actin-binding protein that regulates actin polymerization, filopodia dynamics and increases the branching of proximal dendrites of developing neurons.
Subcellular location: Nucleus speckle {ECO:0000269|PubMed:24349419}. Cell projection, lamellipodium {ECO:0000269|PubMed:24782708}. Nucleus {ECO:0000269|PubMed:24782708}. Cell projection, growth cone {ECO:0000269|PubMed:24782708}. Cell projection, dendrite {ECO:0000269|PubMed:24782708}. Note=Localizes to somata and dendrites in cortical neurons. Colocalizes with G- and F-actin in growth cones and proximal dendrites (PubMed:24782708). Colocalizes in the nucleus with PTK2 (PubMed:24782708). {ECO:0000269|PubMed:24782708}.
Interaction partners:
- tRNA pseudouridine synthase Pus10
Sequence:
MEELRCPEAKLAPPEVVIATEAPPPSLVDRYFTRWYKADVKGKPCEDHCILQHSNRICVITLAGSHPVLQSGKAIQRISYQISNNCSRLENKVSGKFKRGAQFLTELAPLCKIYCSDGEEYTISSCVRGRLMEVNENILHQPSLLQEKPSTEGYIAVVLPKFEESKSVTEGLLTQQQYEEVVVKRTNATATTP
Protein: Neuroendocrine convertase 2 (NEC 2) (EC 3.4.21.94) (KEX2-like endoprotease 2) (Prohormone convertase 2) (Proprotein convertase 2) (PC2) (P16519)
Organism: Homo sapiens (Human)
Function: Serine endopeptidase which is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells.
Subcellular location: Cytoplasmic vesicle, secretory vesicle. Secreted {ECO:0000269|PubMed:28719828}. Note=Localized in the secretion granules.
Interaction partners:
- Neuroendocrine protein 7B2
- Insulin
- Carboxypeptidase E
- Thrombomodulin
- Pro-glucagon
- Secretogranin-1
- Somatostatin
Sequence:
MKGGCVSQWKAAAGFLFCVMVFASAERPVFTNHFLVELHKGGEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEWTLMLHGTQSAPYIDQVVRDYQSKLAMSKKEELEEELDEAVERSLKSILNKN
Protein: Inactive phospholipase C-like protein 1 (PLC-L1) (Phospholipase C-related but catalytically inactive protein) (PRIP) (Q3USB7)
Organism: Mus musculus (Mouse)
Function: Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor. Acts as an inhibitor of PPP1C (By similarity). Involved in the assembly and/or the trafficking of gamma-2 subunit-containing GABA A receptors.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Gamma-aminobutyric acid receptor subunit gamma-2
- Gamma-aminobutyric acid receptor subunit gamma-1
- Gamma-aminobutyric acid receptor subunit alpha-1
- Gamma-aminobutyric acid receptor subunit alpha-6
- Gamma-aminobutyric acid receptor subunit alpha-2
- Gamma-aminobutyric acid receptor subunit epsilon
- Gamma-aminobutyric acid receptor subunit delta
- Gamma-aminobutyric acid receptor subunit alpha-5
- Gamma-aminobutyric acid receptor subunit alpha-3
- Gamma-aminobutyric acid receptor subunit beta-1
Sequence:
MAEGAASREAPAPLDVAGGEDDPRAGADAASGDAPPPALGGRMRDRRSGVALPGAAGVPADSEAGLLEAARATPRRSSIIKDPSNQKCGGRKKTVSFSSMPSEKKISSAHDCISFMQAGCELKKVRPNSRIYNRFFTLDTDLQALRWEPSKKDLEKAKLDISAIKEIRLGKNTETFRNNGLADQICEDCAFSILHGENYESLDLVANSADVANIWVSGLRYLVSRSKQPLDFIEGNQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPTLKESKIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELCTRPEVYFLLVQISKNKEYLDANDLMLFLEAEQGVTHITEDMCLDIIRRYELSEDGRQKGFLAIDGFTQYLLSPECDIFDPEQKKVAQDMTQPLSHYYINASHNTYLIEDQFRGPADINGYVRALKMGCRSIELDVSDGPDNEPILCNRNNMAMHLSFRSVLEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMKKVFGEKLYTEAPLSSESYLPSPEKLKNMIIVKGKKLPSESDLLEGEVTDEDEEAEMSRRMSGDYNGEQKHIWLCRELSDLVSICKSVQHRDFELSMKTQNYWEMCSFSETEASRIANEYPEDFVNYNKKFLSRVYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPSIMRDEVSYFSANTKGIVPGVSPLVLHIKIISGQNFPKPKGACAKGDVIDPYVCVEIHGIPADCCEQRTKTVQQNSDNPIFDETFEFQVNLPELTMVRFVILDDDYIGDEFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHVTLFVHIAITNRSGGGKPQKRSLSVRMGKKVREYTMLRNIGLKTIDDIFKIAVHPLREAIDMRENMQNAIVSVKELCGLPPIASLKQCLLTLSSRLITSDSTPSVSLVMKDCFPYLEPLGAIPDVQKRMLAAYDLMIQESRVLIEMADTVQEKIVQCQKAGMEFHEELHNLGAKEGLKGRKLNKAIESFAWNITVLKGQGDLLKNAKNEAVENIKQIQLACLSCGLSKGPGGGSEAKGKRSLEAIEEKESSEENGKL
Protein: Enhancer of mRNA-decapping protein 3 (Q9VVI2)
Organism: Drosophila melanogaster (Fruit fly)
Function: In the process of mRNA degradation, may play a role in mRNA decapping.
Subcellular location: Cytoplasm, P-body {ECO:0000269|PubMed:17923697}. Note=Processing bodies (PB).
Interaction partners:
- m7GpppN-mRNA hydrolase
- ATP-dependent RNA helicase me31b
- Decapping protein 1, isoform A
- Enhancer of mRNA-decapping protein 4 homolog
- Protein associated with topo II related - 1, isoform A
- 5'-3' exoribonuclease 1
- U6 snRNA-associated Sm-like protein LSm1
- Trailer hitch, isoform H
- RNA helicase
- Small ribosomal subunit protein eS28
Sequence:
MGPTDQDWIGCAVSIACDEVLGVFQGLIKQISAEEITIVRAFRNGVPLRKQNAEVVLKCTDIRSIDLIEPAKQDLDGHTAPPPVVNKPTPVKLPHFSNILGKQQQLQLQQQQQQLQLQQQQKQQFQEQEREQDLPSTPRSRANDNGRVAAGGASSSSGPRGNFNSALSDKMHQLKLIETNGSNGTLRTPQTSRASSAQQQPQISTTPNSVAAFFGNMIPPKVEVKLGSYVSNTRESYCSSSGDSGEATGLSLGSSKPIDIVSNGDGFYKQTAASSYGNTNGNVRRNGNANNNGNGTGNGSYTNGNGNGNGKNKRNRVRRESSMRQQQVQLTFGSEADDPLIHEDFDFEGNLALFDKQAIWDDIESTTQKPDVVRHIVNNHHHKPEQKYRHDENILASKPLQLRQIESMFGGSQDFVTDDGLIIPTIPAYVRNKIEISADKAGLSLQRQIDILARGASDLAITLLGGARRLTPANNHQWPKIAIICDGGKNMRTINIGAATGRQLASHGLTVLLYVEQAKLLEQNSSSPEISLFKATDNVIVHSVDALPTPDLVILSTNTANLSDAIRKWLSVNRASVLAIDPPPCGINEVAIKYSILPILPLNGISTATTSSSSSAAATPTPIASTSAAASATKSAASTNNCGKLYLCNLGIPDKFYRDCGIKYKSPYGHKYVIPIHSKD
Protein: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (A0A8J8YH81)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR038126}.
Interaction partners:
Sequence:
MMMMALSKTFGQKPVKFQLEDDGEFYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIVASSHAHLSVLLHVDNRRAELTCMYPFRGPPCAWGLPDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYLREQKAKRNSQWVPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLCFDDHDPAVIHENASQPEVLVPIRLDMEIDGQKLRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLTFVPAIASAIRQQIESYPTDSILEDQSDQRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQKTYAFSENPLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW
Protein: Protein LSM14 homolog A-A (RNA-associated protein 55A-A) (RAP55A-A) (xRAP55) (xRAP55A) (A0A8M2)
Organism: Xenopus laevis (African clawed frog)
Function: RNA-binding component of messenger ribonucleoprotein complexes (mRNPs), storage particles that mask maternal mRNAs from the translational apparatus during oocyte maturation. Acts as a repressor of mRNA translation. Probably involved in the storage of translationally inactive mRNAs in the cytoplasm in order to prevent their degradation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17074753}. Cytoplasm, P-body {ECO:0000250|UniProtKB:Q8ND56}. Cytoplasm, Stress granule {ECO:0000250|UniProtKB:Q8ND56}. Note=Localizes to cytoplasmic particles in stage VI oocytes and eggs. {ECO:0000269|PubMed:17074753}.
Interaction partners:
Sequence:
MSGGTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRPIPPRDEIFEYIIFRGSDIKDLTVCEPPKPQCSLPQDPAIVQSSLGSSSASSFQSVSSYGPFGRMPAYSQFNTGPLVGPQFGAVGVGSSLTSFGAETTSSTSLPPSSAVGTSFTQEARTLKTQSSQGQSSSPLDSLRKSPNIEQAVQTAAAPHAPSTATVGRRSPVLSRPVPSSIQKTAESPEQRKGELHKMQRPDIDQLKNDKNDPSKRQPVLSALQPRRGRGGNRGGRGRFGVRRDGPMKFEKDFDFESANAQFNKEEIDREFHNKLKIKDDKPEKPVNGEDKTDSVVDTQNSEGNAEEEEVLAGGVCYYDKTKSFFDNISCDDNRDRRQTWAEERRINVETFGLPLRSNRGRGGFRGRGGGMGFRGGRGRGGERRGAPGGGGFGPARGFRGGFRGGRGGREFADYEYRKDNKVAA
Protein: Neurogenin-1 (NGN-1) (Neurogenic differentiation factor 3) (NeuroD3) (Neurogenin-related protein 1) (O42606)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Transcriptional regulator. Activates transcription by binding to the E box-containing promoter (By similarity). Mediates neuronal differentiation. Required for the development of Rohon-Beard spinal sensory neurons and dorsal root ganglion neurons, but not for primary motoneurons or autonomic neurons. Required for development of all cranial ganglia but not associated glial cells. Regulates epiphysial neurogenesis, acting partially redundantly with ascl1a and downstream of flh. Required for the development of basal forebrain dopaminergic neurons; involved in the specification of dopaminergic progenitor cells. May be involved in maintaining rhombomere boundaries in the hindbrain.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- ELAV-like protein
- Achaete-scute homolog 1a
- Paired box protein Pax-6
- Neurogenic locus notch homolog protein 1
- Delta-like protein A
- Hairy-related 6.
- Transcription factor Sox-2
- Transcription factor HES-5
- Transcription factor SOX-10
- Insulin gene enhancer protein isl-1
Sequence:
MEIVYSDMETSSCDYSFSHTDDEDSRSSLHPASPASSCGKPPASPAGLQQKKRRRGRARNETTVHVVKKNRRLKANDRERNRMHNLNDALDALRSVLPAFPDDTKLTKIETLRFAHNYIWALSETIRIADQKQGKSRDGPLLLPGLSCMADAPSPGSDSCSWPSGASSSSSSPSYCNSDPGSPAAMDDFGYLQTDVVYSYRNFVPSIY
Protein: Mcf.2 transforming sequence (Q8C067)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MAEANPPRGKMRFRRNAASFPGSLHLVLVLRPTSFLQRTFTDIGFRFSQEDFMLKLPVVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSEWIIFRNAIEKFAVTVKEMAQMLQSFGTELAETELPQDILSIEEILAGRAERYHLLKNDLTAVTKEGKVLLMNLQVPATEETVSSSLECTQHINGDWQTIKKLLAQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDFQEAVTQVEFLLSQQRELGDITGNLAQVKQRLKKLEILDDKSQELLTKARIVILRGHKLASNHHYALDLICQRCNELRYLSDILVNEIRTKRVQLSRTFKVHRLLQQARQCCDQGECLLASQGMDKFQTKEDAQKALQDVDNFLQMAMPFINYDIESLQYEFDVLLSPELKAQMQNIQLKLENIRSAFQNQQAGCKSLKEVPEGAFQNLVPASENVMRSRMIFFSPKHVKKSWRQIHAQSNVKVEAVEDSQEKNSDQSPKLDNSLDILKNHVLNELIQTERAYVRELFTVLLGYRSEMDNPQMFDLMPPLLRNKKDVLFGNMAEIYEFHNNIFMSRLEDCSDAPERVGPCFLERKDDFQMYAKYCQNKPRSELIWRKYSECAFFQECQRKLKHRLGLDSYLLKPVQRITKYQLLLKELLKYSKEGEGTTKLKEALDSMLELLKSVNDSMHQTAINGYVGNINELGKMVLQGSFNVWLGHRKGATKMKDFARFKPMQRHLFLYEKAVMFCKRRFESGEGADRYPSYSFKHCLKMEDVGITEHVKGDNRKFEIRYSEKEEIYIVQAPNVDVKMLWLKEIRKILVQQKELMTAKTQQDQALDQDQLFPQQQNAELCKSSPFCVCEETLFNATEAGAEVEQAGALIKVREAAVLAQAEASSAAWNGMLPSAEGAAAIAEHSYNYFSSNNDHGEDRTQMRHMSEVTF
Protein: Mitochondrial transcription termination factor family protein (F4JSY9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MEVTNTSSIMWFFRDKGFDDPSIDKMLRKCKQLEKAQSDVASENWDYLSNIVGIQERKLPYIVSRCPKILTLRLDERLIPMVECLSSLGRNPREVASAITKFPPILSHSVEEKLCPLLAFFQALGVPETQLGKMILFNPRLISYSIDTKLTVIVSFLASLGLDQDGMIGKVLVKNPFLMGYSVDKRLRPTTEFLKSSVGLSEDGIKSVVMNFPQLLCRDVNKILKPNYDYLKECGFGDSQIATMVTGYPQILIKSVKNSLQPRIRFLVQVMGRGMDEVASYPEFFHHGLKKKVESRFKLVKKNNIDCSLREMLDCNTKKFHEKFGFSEVFNCNQNGMYMLLDKTEYAAMQSSCLSEVWVGKKPLVIPQIWRPLVKGHI
Protein: Bub3 interacting GLEBS and zinc finger domain protein, isoform A (GH18623p) (Q9VJI6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MGRKKKKASKPWCWYCNREFDDEKILVQHQKAKHFKCHICHKKLYTGPGLSIHCMQVHKETVDKVPNSLPNRSNIEVEIFGMDGIPAEDLRDHERQKNGGKSDSDDDEPVAKKKVEYAMSVPPPMMMPPNMMPPHMLGQYGMGMMQHMPPLPPYPVPMMPHMMPPRPLFPAAMATTSAAAAAAAAHHHHAAAMAQQKPTFPAYSNATISAPPTTNHAGGASSAPPSGPPDAQQHQQRPPAPPAASGTSAAAVTTKIMHPQEDLSLEELRARQPKIQARLAAALASLANPQSRKSPSNNGGPSTSIPTTPPPPSLAGISPTGSNSSSGMANSIVVSAAMSKAQEVSSYHSYRNHSQYK
Protein: Phosphoprotein phosphatase (Q99YM9)
Organism: Streptococcus pyogenes serotype M1
Interaction partners:
Sequence:
MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAGNIASEMTVTDLGREWVKTDFTELSQIRDWLFETIQSENQRIYDLGQSEDFKGMGTTVEAVALVESSAIYAHIGDSRIGLVHDGHYTLLTSDHSLVNELVKAGQITEEEAASHPQRNIITQSIGQASPVEPDLGVRVLEPGDYLVINSDGLTNMISNDEIVTILGSKVSLDEKNQEMIDLANLRGGLDNITIALVHNESEDVE
Protein: YTH domain-containing family protein (Q9VBZ5)
Organism: Drosophila melanogaster (Fruit fly)
Function: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA processing and stability. Together with Fmr1, regulates axonal growth in the mushroom bodies and neuromuscular junctions by repressing the translation of several mRNAs, such as those of chic and futsch.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:27919077, ECO:0000269|PubMed:27919081, ECO:0000269|PubMed:28675155}.
Interaction partners:
- N
- N
- Pre-mRNA-splicing regulator female-lethal
- poly
Sequence:
MSGVDQMKIPGNTAKSVEERNIPWSQQVDEASYENLSSPTHDEVSGNDNSMQFQYPPFNFKENCNTPWNNMNKGRKANANHDSYRRHGHSIPNNTRRDEHQVNPWNSRKPAAQSFRNENDQPSTKLDNRTSDEAQNQEVVAAPKKTTWASIASQPAKLTSRAASTTSNSKKKGPGMPPPPMVPGKHNLDVNVWDLPNNKPPPVPSPPSPIDLGYSDLSSDFSISSNTAPPLGARAEKVHKDTENFLKYEHKGLGNNNNFSRAKVSPTGPVRRNLGPQQPVHHAAPRPATNAGPFGPPNARRHDGGPHPSRNSERSGNYSSFRGSEFESASKFEYRDENQSRPVEATSATEELPVDSQLVLDELKDKNNYNPKVLDLKKAGSARFFVIKSYSEDDIHRSIKYEIWCSTDHGNKRLDDAFKERHEEGGNIMLFFSVNGSGHFCGMAQMMTPVDYNSTSSVWSQDKWRGKFKVKWIYVKDVPNGTLRHIRLENNENKSVTNSRDTQEVPNDKGIEVLQILHSYNHSTSIFDDFFHYEKKQEEEVSSKRPPMHGPDGNNHAPAPLARSFNRQADDKDRDRDGRGGMSQKHFNSGGGAGFRNPGHRGGAGSGGSHNNYSEYRRGFDIHKSSSDYQFKDRDGPDFDRENDFGSHYGSNNRKNEYKHNNTNKARLKTRDRDFSTEQIKIGVRFKDTDKDKMRSNEYS
Protein: Inner membrane protein YqjA (P0AA63)
Organism: Escherichia coli (strain K12)
Function: May be a membrane transporter required for proton motive force (PMF)-dependent drug efflux. Required, with YghB, for the proper export of certain periplasmic amidases and, possibly, other Tat substrates. May play a role in determining membrane lipid composition.
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- Modulator protein MzrA
- TVP38/TMEM64 family inner membrane protein YdjZ
- TVP38/TMEM64 family membrane protein YdjX
- Inner membrane protein YqaA
- Inner membrane protein YebE
Sequence:
MELLTQLLQALWAQDFETLANPSMIGMLYFVLFVILFLENGLLPAAFLPGDSLLVLVGVLIAKGAMGYPQTILLLTVAASLGCWVSYIQGRWLGNTRTVQNWLSHLPAHYHQRAHHLFHKHGLSALLIGRFIAFVRTLLPTIAGLSGLNNARFQFFNWMSGLLWVLILTTLGYMLGKTPVFLKYEDQLMSCLMLLPVVLLVFGLAGSLVVLWKKKYGNRG
Protein: Flavin-containing monooxygenase FMO GS-OX-like 2 (EC 1.8.-.-) (Flavin-monooxygenase glucosinolate S-oxygenase-like 2) (Q9FWW9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the conversion of methylthioalkyl glucosinolates of any chain length into methylsulfinylalkyl glucosinolates.
Interaction partners:
Sequence:
MATSHPDPTTSRHVAVIGAGAAGLVAARELRREGHSVVVLERGSQIGGVWAYTSQVEPDPLSLDPTRPVVHSSLYRSLRTNIPRECMGFTDFPFATRPHDGSRDPRRHPAHTEVLAYLRDFAKEFDIEEMVRFETEVVKAEQVAAEGEERGKWRVESRSSDGVVDEIYDAVVVCNGHYTEPRHALITGIDSWPGKQIHSHNYRVPDQFKDQVVIVIGSSASGVDICRDIAQVAKEVHVSSRSTSPDTYEKLTGYENLWLHSTIQIAREDGSVVFENGKTIYADTIMHCTGYKYYFPFLDTKGEVTVDDNRVGPLYKHVFPPALAPSLSFIGLPWQITPFPMFELQSKWVAAVLSGRVSLPSQDEMMEDTKAFYDKLEASGIPKRYTHLMPDDSQFEYDNWLADQCEYPRIEKWREQMFYIGFKRIYAQSSTYRDNWDDDHLIVEAYDDFVKFMSSYQELLPMLKT