Protein: Intermembrane lipid transfer protein VPS13 (Vacuolar protein sorting-associated protein 13) (G0S3B8)
Organism: Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) (Thermochaetoides thermophila)
Function: Mediates the transfer of lipids between membranes at organelle contact sites (By similarity). Binds phospholipids, including phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA), and phosphatidylserine (PS). May play a role in mitochondrial lipid homeostasis, Golgi vesicle transport, reticulophagy, actin cytoskeleton organization and formation of the prospore membrane (By similarity).
Subcellular location: Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MLEGLVAGLLNRFLGMYVKNFDPKQLKWEVWNGKVRLDNLELQREALDQLKLPINVIKGHLGHLVLHIPWKTLASEQVKINIEDVFLLASPKEEAEYDEDEEARRRHRLKMEKLDSAELLKERSQEGLSEEEQKRTQTFAQALVTKIVDNLQITIRNIHIRYEDAISAPGHPFALGITLEEFSAVSTDSDWTPAFITSIQSAHKLATLESLAIYWDTDAKLIGPGREPHEHSDQIPHDEMLKFFREMIAKGEADLSSEHQFILKPVSGQAKIEIDKTGSHTVPRYKANLLFDEIGVVLDDQQYRDALMMVDLFHYFIRHQEYKKFQPKGVTPKEDPRAWFRFAGNAVLSKIHERNRRWSWDYFRERRDDRRRYIELFKKTKQNIQLTPEEREDLDKLEWKLSYEDLRFWRSLARNQLKKENAEALKNKPPPQPQQQQGWLSWVWGSKPVQPQQEEQQGDENTRITEAQRKELYEVIQWDEKAALAAEIDVPRDSVRLLIETSLSTGSFTLRQNPHGDARDLISLHFDLFRAKGLTRPDSFLIDISLGGFRVNDNTTPDSLYKEIVRVKDAPNTEGQKRYSIADLELTVDEEAFFELQVEQHPLDGQGDVAVTMKLKPLEIIWNPNVVVGIADFFRPPERHMESINALLETANATVEGLRAQTRAGLQFALEEHKTVNAKLDLQAPLIILPESITTPNSTCLIVDAGHISVNSELVDKETMKQVQSTQDRPCTEEDLRRLEELMYDRFLVKLTSTQVLIGPSVEITKQQLVQRDEKRQLHIVDQINLDFVVAMSILPKAPNLTKLKISGHLPVLQVNASDSKYKHLMRIIEVAIPKLYDVEPVLAPSGSHPTIRPRLASDASTRSRRASFRKASTQFLQFVSQQQEIVLDESDSDDDSEKFEDAKDTSVDEQLRIQQRIFDFKFTVDQLRGSLYRSDPEGKHPDQLLVELVAENFGVEYHLRPYDMSAMVSLGSVTMDDFVENPPAEFKSIVSSGDIEDRKQARDLVRVKFVRVKKESPEFMSVYDGIETNVDVAISTINLVVTRKTLLTLLDFILVTFSNPQPAAPVATRMAVTDQESETNIIVQPPPIESGPIRVKVDLKSIRMILNNDGIRLATLSFNHADVGVYILGRYMRVSAKLGDLSLVDDVNLGVSEDSSLRQLVTIQGNELADFRYEYFDPDKPEKNPGYDSSIYLRAGSVKVNFIEEPFRKIVDFLVKFGKMQAIYNAARMAAANQAQQLQQSQSRIKFDIVVKTPIVVFPRVVMSPKPKRDVITAYLGEIYAQNAFVPLDDSEKADMAMKLTTGIRNIRLTSHFHYSEGRDEVLELIDHVDLGFTIIYAEHKEGIKRPDLEIEGSMSDFNLRITPYQLSALLAISQSVPTVFAADVEQHTADAERDVDVATLERARTMPSYSGASEEKVIDMAPELGTHGEAWTKLDLVFTVNTIGLELINAEEDYPVGDLEAASLSRFSLNSSRLKTRMDSNGSLEAEFVIQAFTIYDTRHRETNKFRRIMTSGNSNVDQLMASITMTGGKDRNIIAMVAIDSPRFIFALDYLFAIQKFITIGTTLPEAPIPEKSPMETPEETSDADSVRVGSSGRHSESSAGSGQQLVPVGSQQQQPVLAASEQATTSIAFRVNIVDAQVILIANPLSSSSEAMVLGTKQVVLSQQHSLTFQISECGMFLCRMDRFDDSRLRIIDDFSVKVAVDMSKPNITQVHADIEPLILRLSLRDILLVMQTIAKASELSGGTPSETASKTVAERKAQQLRAAGLKHRTASGKGTSTLATRTRHASQSAASHSGKTTTLVMQEVAKQTQRFEELILTVEGTRMVLLGDVHELPIIDMSVKTFTIHAENWTSNLKAETAFDMYMNVYNFAKSAWEPLIEPWQVGFGITREAKTGVLSVDVTSKKTFDVTITAATIALLSQSFAFFSKEQDVLTKPRGVEAPYRIRNYTGFDVIISTKRQIPGASPTTEQQLPTMTLRLEDGQEAPWSFEEWEKMRESLMTESSTANSISVQLVGSGFQEVKSIRLTREGEFLFGLKPKTQQVLHKLLVEIKLGKDNIKYVTLRSPLLVENDTGIVVELGVYDAHEGHLLKIERINPGESKPAPVGAAYFKSLLVRPDPGFKYGWSSDTLWWRDLLKRPTKTLVCKSEQYGGEVFYFRLHARWDQANPLTRNYPYMRLKLTAPLTIENLLPYDFKYKIYDRVNKQEWNNFLRKGGSIPVHMVDLSHTFLLGIEMQDTPFQASEFVVINTGNADDFKKDSHLVVKDNAGMPLNLRLHYFRIPDGGGSFKVTVYSPYVILNKTGLDVSVRSKGFMQSARAAAGQTLIDVGGDGQKKARPLMFSFHNDDHRNRALLKAGDSEWSKPQSFDAIGSTTEVVLQTANRNAEIHLGVTVDSGQGKYKMVKVVTLAPRYVIHNKLGEDINIREPSSSFWIPLKHGAHRPLHWLQRGAVKQLCLCYPGVDNQWTAPFNISDLGITHLKIARAGQRQRLIRVEILMEDATIFLNLSMEQRNWPFSMRNESDTEFTFYQVNPTIEEDASEDRSGWRPVRYRLPPRSIMPYAWDFPAAKHKEICICAYNKERHVKLQEIGNLMPMKLALPNGESKTIDINVTADGPTQTLILSNYRQSKSLYRQRSNAGSISGREGFEAKEFDTGTTFRATLRLSGIGVSIINTQLKELAYITLRDVQLRYSDSALYQTFSLAVKWIQIDNQLYGGIFPMILYPSVVPKRAQEIDAHPSLHAMVTRVKDESYGVEYIKYATVLLQEMTVELDEDFIYAVLEFSKIPGASWESTQEEDRLCDDSVDVPQPKQQQAGRDIYFEVLNIQPMQLDLSFVRTERVNVEDKTSSRNPVMFFFNVMTMAIGNINDAPVRFNALMLENVRVSIPVLIQNISNHYSQEALYQIHKILGSADFLGNPVGLFNNISSGFADIFYEPYQGLIMSDRPEDFGLGLARGAGSFFKKSVYGFTDSFSKVTGSFAKGLAAATMDKQFQDRRRITRARNRPKHALFGVTAGANSLISSVASGVGGLARKPLEGAEQEGALGFFKGIGKGVVGLATKPAIGVLDFASNISEGVRNTTTVFSSSEASELDRVRLPRHIAADGIVRPYSQREALGQSWLKQVDNGKYFDEAYIGHLELPTEDMVVMVTYARILLIRSRRLQTEWDVPLKDVQTIAKERTGLSLTLRGGTNGPFIPVAQESGRAFLYRMVAVAVEEFNRRFRGLE