wanglab/gogpt-training-data huggingface dataset:
Protein: Pseudouridine synthase 1 (G8JLB3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAGNAEPPPAGAACPQDRRSCSGRAGGDRVWEDGEHPAKKLKSGGDEERREKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDARTYCYLLPTFAFAHKDRDVQDETYRLSAETLQQVNRLLACYKGTHNFHNFTSQKGPQDPSACRYILEMYCEEPFVREGLEFAVIRVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGTEKVDVPKAPGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQEEGKVAAFKEEHIYPTIIGTERDERSMAQWLSTLPIHNFSATALTAGGTGAK
Protein: Larval cuticle protein 2 (Larval cuticle protein II) (P07187)
Organism: Drosophila melanogaster (Fruit fly)
Function: Component of the larval cuticle.
Interaction partners:
- Larval cuticle protein 3
- Larval cuticle protein 4
- Larval cuticle protein 9
- Uncharacterized protein
Sequence:
MFKFVMILAVVGVATALAPVSRSDDVHADVLSRSDDVRADGFDSSLHTSNGIEQAASGDAHGNIHGNFGWISPEGEHVEVKYVANENGYQPSGAWIPTPPPIPEAIARAVAWLESHPPAPEHPRHH
Protein: Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase (EC 2.4.3.8) (Alpha-2,8-sialyltransferase 8A) (Ganglioside GD3 synthase) (XlGD3 synthase) (Sialyltransferase 8A) (SIAT8-A) (Sialyltransferase St8Sia I) (ST8SiaI) (Q6ZXA0)
Organism: Xenopus laevis (African clawed frog)
Function: Catalyzes the addition of sialic acid in alpha 2,8-linkage to the sialic acid moiety of the ganglioside GM3 to form ganglioside GD3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid. Glycosphingolipids are required for convergence extension movements during early development. Can catalyze the addition of a second alpha-2,8- sialic acid to GD3 to form GT3 (By similarity). Can use GM1b, GD1a and GT1b as acceptor substrates to synthesize GD1c, GT1a and GQ1b respectively (By similarity).
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:17333390, ECO:0000269|PubMed:18095347}; Single-pass type II membrane protein {ECO:0000269|PubMed:17333390, ECO:0000269|PubMed:18095347}. Note=PubMed:18095347 report localization in the endoplasmic reticulum. {ECO:0000269|PubMed:17333390, ECO:0000269|PubMed:18095347}.
Interaction partners:
Sequence:
MWGRWRGAGGRRGVAQPVIPQMKLLGGRVPLGASALGLLIVCWFYIFPGGERLPGHKEMIRQVLQFGPRWGRNRSSGDSFRKLLQDCCDPPRLFSMTKANTALGENLWYDGEFFQSLTIDNTTRSLFPQDTPIKLPLKRCSVVGNGGILKNSRCGEQIDEADFVMRCNLPPLSREYTDDVGTKTQLVTVNPSIIDKRFQNLLWSRKSFVESVSVYKQSYVYMPAFSTKRGTDPSLRVYYTLEDFGTNQTVLFANPNFLRNVGKFWKSKGVHSKRLSTGLFMVSAALSLCEEVTIYGFWPFQMDLGGRHISHHYYDNMLPLSGVHAMPEEFLQLWHLHKSGVLQMQLDQCKKDVSSKKPH
Protein: Expressed protein (RNA-binding ASCH domain protein) (Q9SK61)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein-tyrosine-phosphatase PTP1
- MACPF domain-containing protein At4g24290
- MACPF domain-containing protein CAD1
- Protein SIEVE ELEMENT OCCLUSION B
- Protein SIEVE ELEMENT OCCLUSION A
- Phosphoinositide phosphatase SAC7
- Phosphoinositide phosphatase SAC6
- Phosphoinositide phosphatase SAC8
- AP-2 complex subunit sigma
- Clathrin heavy chain 2
Sequence:
MSRGNYKNPCLTMHQPWASLLVHGIKRIEGRSWPSPIRGRLWIHAASKVPDEATIKAMEEFYQQIYAVDGITDIQFPQHYPVSRLIGCVEVVGCVTSDELQNWDALPQGVRLEGQTNFCWLCEKPQKLIIPFEMRGYQGVYNLENKIYVAAARGLMPSQNSFKVKFPLPDPKDPFSLKPGSIPCTMQEKKELDSKQVTSLTAAIKQVTSLTAAIAGAKAAATQFSKKGQSLQTNNIFDYTTRSKSKVIEDEAAESLDNPVLGSGGTSDRTYRTRSKNRGTQMGEEVCSESSNSSSKVESSQRSAVTKSEDRNTRIGERRFDPGSARIMAAAIRNLKPPS
Protein: Ras-related protein Rab (Q6FGU7)
Organism: Homo sapiens (Human)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00046278}; Lipid-anchor {ECO:0000256|ARBA:ARBA00046278}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00046278}. Membrane {ECO:0000256|RuleBase:RU367128}; Lipid-anchor {ECO:0000256|RuleBase:RU367128}.
Interaction partners:
Sequence:
MGSRDHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVGVDFALKVLQWSDYEIVRLQLWDIAGQERFTSMTRLYYRDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPNGEPVPCLLLANKCDLSPWAVSRDQIDRFSKENGFTGWTETSVKENKNINEAMRVLIEKMMRNSTEDIMSLSTQGDYINLQTKSSSWSCC
Protein: Catenin alpha-1 (Alpha E-catenin) (Q9PVF8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell junction, adherens junction {ECO:0000269|PubMed:10456847, ECO:0000269|PubMed:20736288}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P26231}. Cell membrane {ECO:0000250|UniProtKB:P26231}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000250|UniProtKB:P26231}. Cell junction {ECO:0000269|PubMed:10456847, ECO:0000269|PubMed:16319113, ECO:0000269|PubMed:27612508}. Cytoplasm {ECO:0000269|PubMed:10456847}. Nucleus {ECO:0000269|PubMed:20736288}. Note=Localized in the ooplasm during the initial stages of oogenesis. {ECO:0000269|PubMed:10456847}.
Interaction partners:
- Catenin beta-1
- Catenin, beta 2.
- Vinculin b.
- Vinculin a.
- Afadin, adherens junction formation factor a.
- Junction plakoglobin a.
- Tight junction protein 1a
- Actinin, alpha 4.
- Actin, cytoplasmic 1
- Catenin
Sequence:
MTSINTANINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNSSNKGPSNKKKGRSKKAHVLAASVDEATQNFLEKGEKIAKESQFLKEELTAAVEDVRKQGESMKMASGEFAEDPCSSVKRGNMVRAARALLSAVTHLLVLADMADVYQLLLQLKLVEENLMKVRNAGTEQDLGIQYKALKPEVDKLNMMAAKRQQELKDVHHKDQMAAARGVLQRNVPMLYTASRACLQHPDVAAYKANRDLIYKQLQHAVSGISNAAQATSSEDSSFSQTAGGGELAYALNNFDKQIIVDPLSFSEERFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNSVRQALQDLLSEYMGNAGRKEKSDALNTAIDRMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMAASQLETLCPQVINAALALAAKPNSKVAQDNMDLFKDQWEKQVRVLTDAVDDITSIDDFLCVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRGRAARVVHVVTSEMDNYMPGVYTEKVLEATKLLTETVMPRFTEQVEAAVEALSANNGQPVDENEFIDASRLVYDGVRDIRKAVLMIRTPEELDDSDFETEDFDSRSRTSVQTEDDQLIAGQSARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRAIADQCPDSACKQDLLAYLQRIALFCHQLNICSKVKAEVQNLGGELVVSGLDSAMSLIQAAKNLMNSVVSTVKASYVASTKYQKSQDMQSLNMPAISWKMKAPEKKPLVKREKLDDGQTNKVKRSSQKKHINPVQALSEFKAMDSI
Protein: Profilin-1A (Acidic profilin IA) (Profilin IA) (P68696)
Organism: Acanthamoeba castellanii (Amoeba)
Function: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Subcellular location: Cytoplasm, cytoskeleton.
Interaction partners:
Sequence:
MSWQTYVDTNLVGTGAVTQAAILGLDGNTWATSAGFAVTPAQGQTLASAFNNADPIRASGFDLAGVHYVTLRADDRSIYGKKGSAGVITVKTSKSILVGVYNEKIQPGTAANVVEKLADYLIGQGF
Protein: ribonuclease III (EC 3.1.26.3) (Q2Q3W0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
PRGYQLRLVDHLTKSNGIVYLPTGSGKTFVAILVLKRFSQDFDKPIESGGKRALFMCNTVELARQQAMAVRRCTNFKVGFYVGEQGVDDWTRGMWSDEIKKNQVLVGTAQVFLDMVTQTYVALSSLSVVIIDECHHGTGHHPFREFMRLFTIANQTKLPRVVGLTGVLIKGNEITNVATKLKELEITYRGNIITVSDTKEMENVMLYATKPTEVMVSFPHQEQVLTVTRLISAEIEKFYVSLDLMNIGVQPIRRSKSLQCLRDPSKKSFVKQLFNDFLYQMKEYGIYAASIAIISLIVEFDIKRRQAETLSVKLMHRTALTLCEKIRHLLVQKLQDMTYDDDDDNVNTEEVIMNFSTPKVQRFLMSLKVSFADKDPKDICCLVFVERRYTCKCIYGLLLNYIQSTPELRNVLTPQFMVGRNNISPDFESVLERKWQKSAIQQFRDGNANLMICSSVLEEGIDVQACNHVFILDPVKTFNMYVQSKGRARTTEAKFVLFTADKEREKTIQQIYQYRKAHNDIAEYLKDRVLEKTEPELYEIKGHFQDDIDPFTNENGAVLLPNNALAILHRYCQTIPTDAFGFVIPWFHVLQEDERDRIFGVSAKGKHVISINMPVNCMLRDTIYSDPMDNVKTAKISAAFKACKVLYSLGELNERFVPKTLKERVASIADVHFEHWNKYGDSVTATVNKADKSKDRTYKTECPLEFYDALPRVGEICYAYEIFLEPQFESCEYTEHMYLNLQTPRNYAILLRNKLPRLAEMPLFSNQGKLHVRVANAPLEVIIQNSEQLELLHQFHGMVFRDILKIWHPFFVLDRRSKENSYLVVPLILGAGEQKCFDWELMTNFRRLPQSHGSNVQQREQQPAPRPEDFEGKIVTQWYANYDKPMLVTKVHRELTPLSYMEKNQQDKTYYEFTMSKYGNRIGDVVHKDKFMIEVRDLTEQLTFYVHNRGKFNAKSKAKMKVILIPELCFNFNFPGDLWLKLIFLPSILNRMYFLLHAEALRKRFNTYLNLHLLPFNGTDYMPRPLEIDYSLKRNVDPLGNVIPTEDIEEPKSLLEPMPTKSIEASVANLEITEFENPWQKYMEPVDLSRNLLSTYPVELDYYYHFSVGNVCEMNEMDFEDKEYWAKNQFHMPTGNIYGNRTPAKTNANVPALMPSKPTVRGKVKPLLILQKTVSKEHITPAEQGEFLAAITASSAADVFDMERLEILGDSFLKLSATLYLASKYSDWNEGTLTEVKSKLVSNRNLLFCLIDADIPKTLNTIQFTPRYTWLPPGISLPHNVLALWRENPEFAKIIGPHNLRDLALGDEESLVKGNCSDINYNRFVEGCRANGQSFYAGADFSSEVNFCVGLVTIPNKVIADTLEALLGVIVKNYGLQHAFKMLEYFKICRADIDKPLTQLLNLELGGKKMRANVNTTEIDGFLINHYYLEKNLGYTFKDRRYLLQALTHPSYPTNRITGSYQELEFIGDAILDFLISAYIFENNTKMNPGALTDLRSALVNNTTLACICVRHRLHFFILAENAKLSEIISKFVNFQESQGHRVTNYVRILLEEADVQPTPLDLDDELDMTELPHANKCISQEAEKGVPPKGEFNMSTNVDVPKALGDVLEALIAAVYLDCRDLQRTWEVIFNLFEPELQEFTRKVPINHIRQLVEHKHAKPVFSSPIVEGETVMVSCQFTCMEKTIKVYGFGSNKDQAKLSAAKHALQQLSKCDA
Protein: Cullin-associated NEDD8-dissociated protein 1, C-terminal part (Cullin-associated and neddylation-dissociated protein 1, C-terminal part) (Q5BAH2)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor when interacting with candA-N (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:21119001}.
Interaction partners:
- Cullin-associated NEDD8-dissociated protein 1, N-terminal part
- RING-box protein 1
- Ubiquitin ligase subunit CulD, putative
- JmjC domain-containing histone demethylation protein 1
- Cullin-1
- SCF ubiquitin ligase subunit CulC, putative
- DNA damage-binding protein 1
- Ubiquitin-like domain-containing protein
- SCF E3 ubiquitin ligase complex F-box protein grrA
- E3 ubiquitin ligase complex SCF subunit sconC
Sequence:
MSSDAMSDYSHDDEHDPQTDELRETALVTLEALISSCSSQMQSYLPNTINSALRFLKYDPNVADMGEDEEMSGTQDDGSEDDVTEEPDLEDDDFEDFEEEGGYSDIDDMSWKVRRCAAKLLYAVISTYGRGRALDDTSLYQQIAPAIVARFNKEREESVKLELVSTMDALVRKTAEGSMIMTSSGFLESVGSGSKISRKRRRQDSDASMIDFEPSMGTSSAAGTPLAAPSSPQSGPQSELANALPVIVRSLVTMWKQASIHLKQAIIILLKSLALVRYGGLADHLQQIEDPIADVLKSSLSGAPSASIGISASAGTLQIETLSLISAISETHASDALLPFLIALIPGVIVAVNDKNYKVSSEALAAVEQIVKALTPPRVTTASQDLIFQLEKLYDVSHSRITDTSADLEVRQRAIHVLGVLLARTSDEQGSAFLSFEKRSKGLVTLVDRLKNETTRLSAVRAIDDVAVLCSRKDDVDSNWVREVTAELGAQLRKSDRVLRSASLETLRSLSMNPNTRAHYDGETMKNLEECLIPLISVEDVHLLAPSLIIIAKLVPGNAQLLVNDGLVSAICSIVRTSLAGTVLKALLLLVKVIGEEGSGLTLMQNLLQDVGVNGDTSVVGRSIGTLLVHGGSNVGVRMEDFLSELQKTQDPQRQCLALAILGESALRLGASCSLTPNVFIPHFNSKSEKVRLASATALGNAAAGNVKAYLPTILGGLEKSDPQSYLLLHSVKELLQHPEMVRRDVAPSALKLWQALLVVSKEEDNRAMGAECVGRLALLDPPAYIPQFQEYLANGDAGIRSIVVSAFRFTLSDSRDVFNDVLRPLIVPLLVNMLSDRDLGNHRLALTTLNSAIHNKLALILPHLGELLPAVLGDTQIKPELIREVQMGPFKHKVDDGLELRKSAYETVYAALDTSFSLSHITELYSRILAGIDDEQDIRTICNLMTSKLITLAPEETQRHLDALSERYTAILNFKPKENAVKQEIEKAQEASTGVLKITRELSKAFPNAETMGDHHKWKAYMEMVRAQFGTQLSNLESEF
Protein: ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1) (Protein hennin) (Q640N2)
Organism: Mus musculus (Mouse)
Function: Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic interneurons in the developing cerebral cortex.
Subcellular location: Cell projection, cilium membrane {ECO:0000269|PubMed:17488627, ECO:0000269|PubMed:20231383, ECO:0000269|PubMed:21976698, ECO:0000269|PubMed:23153492, ECO:0000269|PubMed:23817546, ECO:0000269|PubMed:24120134, ECO:0000269|PubMed:24339792, ECO:0000269|PubMed:26582389}; Lipid-anchor {ECO:0000269|PubMed:17488627, ECO:0000269|PubMed:20231383, ECO:0000269|PubMed:21976698, ECO:0000269|PubMed:23153492, ECO:0000269|PubMed:23817546, ECO:0000269|PubMed:24120134, ECO:0000269|PubMed:24339792}. Cell projection, cilium {ECO:0000269|PubMed:25138100}. Note=Associates with the cilium membrane via palmitoylation. Localizes to proximal ciliary membranes, to an inversin-like subciliary membrane compartment, excluding the transition zone.
Interaction partners:
- Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
- Phosphatidylinositol polyphosphate 5-phosphatase type IV
- Intraflagellar transport protein 88 homolog
- Pericentrin
- Centrosomal protein of 164 kDa
- Kinesin-like protein KIF3A
- Meckelin
- Jouberin
- Centrosomal protein of 290 kDa
- G-protein coupled receptor 161
Sequence:
MFSLMANCCNLFKRWREPVRKVTLVMVGLDNAGKTATAKGIQGEHPEDVAPTVGFSKIDLRQGKFQVTIFDLGGGKRIRGIWKNYYAESYGVIFVVDSSDEERMEETKETMSEVLRHPRISGKPILVLANKQDKEGALGEADVIECLSLEKLVNEHKCLCQIEPCSAVLGYGKKIDKSIKKGLYWLLHIIAKDFDALSERIQKDTTEQRALEEQEKRERAERVRKLREEREREQTELDGTSGLAEIDSGPVLANPFQPIAAVIIENEKKQEKEKKKQTVEKDSDVGLLEHKVEPEQAAPQSEADCCLQNPDERVVDSYREALSQQLDSEDEQDQRGSESGENSKKKTKKLRMKRSHRVEPVNTDESTPKSPTPPQPPPPVGWGTPKVTRLPKLEPLGETRHNDFYGKPLPPLAVRQRPNGDAQDTIS
Protein: Histone deacetylase 10, chloroplastic (OsHDAC10) (EC 3.5.1.-) (N-acetylserotonin deacetylase) (Q2QWU2)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Involved in the regulation of melatonin biosynthesis by catalyzing the deacetylation of N-acetylserotonin to produce serotonin. N-acetylserotonin is methylated by acetylserotonin O-methyltransferase (ASMT) to produce melatonin (N-acetyl-5-methoxytryptamine) (Probable). Deacetylates melatonin to produce 5-methoxytryptamine. In vitro, deacetylates N-acetyltyramine and N-acetyltryptamine to produce tyramine and tryptamine, respectively.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:19505461, ECO:0000269|PubMed:29247559}. Mitochondrion {ECO:0000269|PubMed:19505461}.
Interaction partners:
- Os09g0544500 protein
- ARID transcription factor
- Histone H4
- Histone H4
- Lectin
- Os04g0339800 protein
- Os02g0708600 protein
- Os02g0708500 protein
- NAD-dependent protein deacylase
- NAD-dependent protein deacetylase SRT1
Sequence:
MEQLWVPSLPILGGRILPMLRHYCGFGSHHPLTWRSLQITGRKQKHNGCWIAYCLPSHNGTSISDTNGVRKDLALPDNLLRDAHILYCTSPAMGHNKEAHPETNKRVPAIVDALEKLELTSKHRGSQVLEIQDFQPASLDDIALVHSRSYITGLEKAMSRASDEGLIFIEGTGPTYATQTTFQECLLSAGAGITLVDSVVAASKLGPKPPLGFALVRPPGHHAVPEGPMGFCVFGNIAVAARYAQNQHGLKRVMIIDFDVHHGNGTCDAFYEDPDIFFLSTHQLGSYPGTGKIHQVGQGNGEGTTLNLPLPGGSGDYAMRCAFDEVIAPAAQRFKPDIILVSAGYDAHALDPLAGLQFTTGTFYMLAARIREVAAELCGGRCVFFLEGGYNLESLSSSVADTFRAFLGEPSLAARFDDPAMLYEEPTRKIREAIDKAKHLHSL
Protein: N-acetyldiaminopimelate deacetylase (EC 3.5.1.47) (O34916)
Organism: Bacillus subtilis (strain 168)
Function: Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
Interaction partners:
- Diaminopimelate epimerase
- 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase
- Putative dipeptidase YtjP
- Probable N-acetyl-LL-diaminopimelate aminotransferase
- 4-hydroxy-tetrahydrodipicolinate reductase
- Diaminopimelate decarboxylase
Sequence:
MKIEELIAIRRDLHRIPELGFQEFKTQQYLLNVLEQYPQDRIEIEKWRTGLFVKVNGTAPEKMLAYRADIDALSIEEQTGLPFASEHHGNMHACGHDLHMTIALGIIDHFVHHPVKHDLLFLFQPAEEGPGGAEPMLESDVLKKWQPDFITALHIAPELPVGTIATKSGLLFANTSELVIDLEGKGGHAAYPHLAEDMVVAASTLVTQLQTIISRNTDPLDSAVITVGTITGGSAQNIIAETAHLEGTIRTLSEESMKQVKERIEDVVKGIEIGFRCKGKVTYPSVYHQVYNTSGLTEEFMSFVAEHQLATVIEAKEAMTGEDFGYMLKKYPGFMFWLGADSEHGLHHAKLNPDENAIETAVHVMTGYFSVYAN
Protein: Uncharacterized HTH-type transcriptional regulator YdjF (P77721)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Uncharacterized protein YdjI
- Uncharacterized sugar kinase YdjH
- Inner membrane metabolite transport protein YdjE
- Putative metabolite transport protein YdjK
- Uncharacterized zinc-type alcohol dehydrogenase-like protein YdjJ
- Uncharacterized zinc-type alcohol dehydrogenase-like protein YdjL
- NADH-specific methylglyoxal reductase
Sequence:
MAAKDRIQAIKQMVANDKKVTVSNLSGIFQVTEETIRRDLEKLEDEGFLTRTYGGAVLNTAMLTENIHFYKRASSFYEEKQLIARKALPFIDNKTTMAADSSSTVMELLKLLQDRSGLTLLTNSAEAIHVLAQSEIKVVSTGGELNKNTLSLQGRITKEIIRRYHVDIMVMSCKGLDINSGALDSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFVQLADFSHINYIITDKSPGAEWIAFCKDNNIQLVW
Protein: Homeobox protein engrailed-2b (Homeobox protein en-2b) (Zf-En-1) (P31533)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus.
Interaction partners:
Sequence:
MEENDHSNRDVERQDSGDESNRAILPLLQAPGNVLPHRITNFYIDNILRPDFGRRKEGSRRDEINIVERENRCPSAPGSGQVAPVSGEGTSSPRAVNASKKTDISTDESLKSRAETGDQCLSSDSDCSQRCAAQAKQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKTPTKEDKRPRTAFTAEQLQRLKNEFQNNRYLTEQRRQALAQELGLNESQIKIWFQNKRAKIKKATGNKNTLAVHLMAQGLYNHATVTKDDKSDSD
Protein: Amino acid transporter (Q9Z1J7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Melanosome {ECO:0000256|ARBA:ARBA00004223}. Membrane {ECO:0000256|RuleBase:RU361216}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU361216}.
Interaction partners:
Sequence:
MAVDPPKADPKGVVAVDPTANCGSGLKSREDQGAKAGGCCSSRDQVCRCLRANLLVLLTVAAAVAGVVLGLGVSAAGGAEALGHARFTAFAFPGELLLRLLEMIILPLVVCSLIGGAASLDPSALGRLGAWALLFFLVTTLLSSALGVALALALKPGAAFAAINSSVVDSSVHRAPTKEVLDSFLELLRNMFPSNLVSASAAFRIPCGACPQRSNATMDQPHCEMKMNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNDATMVLVSWIMWYAPIGILFLVAGKIVEMKDIRQLFIGLGKYIVCCLLGHAIHGLLVLPLIYFLFTRKNPYRFLWGIVTPLATAFGTSSSSATLPLMMKCVEEKNGVAKHISRFILPIGATVNMDGAALFQCVAAVFIAQLNGMSLDFVKIITILVTATASSVGAAGIPAGGVLTLAIILEAISLPVKDISLILAVDWLVDRSCTVLNVEGDAFGAGLLQSYVDRTKMPSSEPELIQVKNDVSLKPLPLATEEGNPLLKQCREPSGDSSATCEKESVM
Protein: Probable assembly chaperone of rpl4 (Q1MTN8)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Acts as a chaperone for the L4 ribosomal subunit encoded by rpl4A and rpl4B, required for hierarchical ribosome assembly. Shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q03771}. Nucleus {ECO:0000250|UniProtKB:Q03771}. Nucleus, nucleolus {ECO:0000269|PubMed:16823372}. Note=Distributed throughout the cell but is enriched in the nucleus. {ECO:0000250|UniProtKB:Q03771}.
Interaction partners:
- Ribosome assembly protein rrb1
- Ankyrin repeat-containing protein P16F5.05c
- Pre-rRNA-processing protein tsr2
- Phosphoglycerate kinase
- Triosephosphate isomerase
- mRNA 3'-end-processing protein rna14
- Large ribosomal subunit protein uL4B
- Large ribosomal subunit protein uL4A
- tRNA
- Glucose-6-phosphate isomerase
Sequence:
MSVTDAELLEIREKLVKDETSEALILAKKAADKSPKEDGRAFELLGEVYAELADVKKARSAFKEAVSRSKNLTNDQGYEKYLWLAQINDNGSKALKLYQKGVTILERLLIDKGEDADLKKKIQGAYCSIAELFMTDLCMQPDAEENCELYTKLALQIDATNAEALQTLASMRISQQKIEEAKDALSKCLQSISRAATEDSVDLPTYAVRTSIVRLLIEVEMHEEAHQLLVYLQKEDDQILDIWYLLGWNCYVEAQNLQEQGNGSEEEIKELLMNAKFYFISALGVYQKIGWDDEGIKSHIQELLEILNGLGVPNMDEENEEAEWETSENEEEMDED
Protein: Vtg2 protein (A8WGJ1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MMEATQSLVFVEFEKAPVVPVKADYMPRGSLQYEFATEILQTPIQLTKISNAPAQIKEVLKHLVENNVAMVRDDAPLKFVQLVQFLRAATLKDTEAIWAQFKDKPVYRRWLLDTLPAVATPVVLKFIKEKFLAGEFTLTEFIPTLVVALQMVPADLETIQWTASLALHEKIATIPALREVVMLGYGSMIAKYCVAVPTCPAELLRPIHEIATEAISKNDIPEITLALKVLGNAGHPSSLKPIMKLLPVLKTTASALPIGVQVDAILALRSIAKKEPKLVQPVALQLVLERALHPELRMVACILLFETKPSVAAMSSSRWSKTLTKMEAFRKFHKDQYKTHHGDSKSSRSTGSSLEQIQKQSRYLGNTVPPVFAIIARAVRVDRKLLGYQFVAFFDKPSSRVQLIASSIAENDNFKFCADGVLLSKHKVTSKVTWGAECKEYAVTTKAEAGLLGEFPAFRLEWEWERLPIIFTTYAKKLSKHIPMAALQAGFNVERAKNSEKELELTVALPSKRTLNVIVRVPEMTMSRMDIPLPVTVPINPDGTFDVHFYEDIYFRAQNYIYDYTTAQCSMMQDTISTFNNKTYKNEMPISCYQVLAQDCTSELKFVALLKKDEESEKTHLNVKLVDIDIDLYTLGTDAKVKINGLEVPISSLPYQHPSGSIQIREKADGLSLYAPSLGLHEVYFANGDWKIQVADWMKGQTCGLCGKADGEIKQEYTTPSGYLTESSVSFAHSWVLPAESCRNASQCRMKLESVKFEKQVILNGQESKCYSVEPVLRCLPGCAPVRTTPVTVGYHCMSTASNLNMLAGIYEKSVDLRETTDAHVVCRCTEQCA
Protein: PDZ and LIM domain protein 2 (Q6AYD6)
Organism: Rattus norvegicus (Rat)
Function: Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15505042}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:15505042}. Note=Localizes at the cytoskeleton. Colocalizes with beta-1 integrin (ITGB1) and alpha-actinin but not with paxillin (PXN).
Interaction partners:
- Alpha-actinin-1
- Unconventional myosin-VI
Sequence:
MALTVNVVGPAPWGFRISGGRDFHTPIIVTKVTERGKAEAADLRPGDIIVAINGESAESMLHAEAQSKIRQSASPLRLQLDRSQTASPGQINGEGSLDMLATRFQGSLRTHHNSQSSQRSACFSPASLSPRPDSPFSTPPPTSPIALSGENVIGCSFQSLTHSPGLAATHHLTYPGQPTSQQAGHSSPSDSTVRVLLHSPGRPSSPRLSSLDLEEDSEVFKMLQENRQGRAAPRQSSSFRLLQEALEAEERGGTPAFVPSSLSPKASLPTSRALATPPKLHTCEKCSVNISNQAVRIQEGRYRHPGCYTCADCGLNLKMRGHFWVGNELYCEKHARQRYSMPGTLSSQA
Protein: L,D-transpeptidase 2 (LDT 2) (EC 2.3.2.-) (Ldt(Mt2)) (O53223)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Function: Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection.
Subcellular location: Cell membrane {ECO:0000255|PROSITE-ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
Interaction partners:
Sequence:
MPKVGIAAQAGRTRVRRAWLTALMMTAVMIGAVACGSGRGPAPIKVIADKGTPFADLLVPKLTASVTDGAVGVTVDAPVSVTAADGVLAAVTMVNDNGRPVAGRLSPDGLRWSTTEQLGYNRRYTLNATALGLGGAATRQLTFQTSSPAHLTMPYVMPGDGEVVGVGEPVAIRFDENIADRGAAEKAIKITTNPPVEGAFYWLNNREVRWRPEHFWKPGTAVDVAVNTYGVDLGEGMFGEDNVQTHFTIGDEVIATADDNTKILTVRVNGEVVKSMPTSMGKDSTPTANGIYIVGSRYKHIIMDSSTYGVPVNSPNGYRTDVDWATQISYSGVFVHSAPWSVGAQGHTNTSHGCLNVSPSNAQWFYDHVKRGDIVEVVNTVGGTLPGIDGLGDWNIPWDQWRAGNAKA
Protein: Tumor necrosis factor receptor type 1-associated DEATH domain protein (D3ZZC5)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- TNF receptor-associated factor
- FAS-associated death domain protein
- Tumor necrosis factor receptor superfamily member 1A
- Caspase-8
- Receptor-interacting serine/threonine-protein kinase 1
- Tumor necrosis factor
- TNF receptor-associated factor
- Receptor-interacting serine/threonine-protein kinase 3
- TNF receptor-associated factor.
- TNF receptor-associated factor
Sequence:
MAADQNGHEEWVGSAYLFLESSMDKVVLSEAYTDPKKKVAIYKALQAALSESGDSPDVLQILKIHCSDPQLIVQLRFCGRLLCGRFLQAYREGALRTALQRCMAAALAQEAVRLQLELRAGAEQLDSWLTDEERCLNYILAQKPDRLRDEELAELEDEFCKLTCDSTGQGGATQVAPAGSKSLVSSPAEEKPLPAAGQTFLFHGQLIVNRPLNLQDQQTFARSVGLKWRRVGRSLQRSCRALRDPALDSLAYEYERDGLYEQAFQLLRRFIQAEGRRATLQRLVEALEENELTSLAEDLLGQAEPEGGQA
Protein: BCL2/adenovirus E1B 19kDa interacting protein 3-like (BNIP3L protein) (Q6IBV1)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion membrane {ECO:0000256|ARBA:ARBA00004325}.
Interaction partners:
Sequence:
MSSHLVEPPPPLHNNNNNCEENEQSLPPPAGLNSSWVELPMNSSNGNDNGNGKNGGLEHVPSSSSIHNGDMEKILLDAQHESGQSSSRGSSHCDSPSPQEDGQIMFDVEMHTSRDHSSQSEEEVVEGEKEVEALKKSADWVSDWSSRPENIPPKEFHFRHPKRSVSLSMRKSGAMKKGGIFSAEFLKVFIPSLFLSHVLALGLGIYIGKRLSTPSASTY