wanglab/gogpt-training-data huggingface dataset:
Protein: CS domain-containing protein (Q38BY3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Heat shock protein, mitochondrial, putative
- Heat shock protein 83
- Lipophosphoglycan biosynthetic protein, putative
- Serine/threonine-protein phosphatase
- Serine/threonine-protein phosphatase T
- Activator of Hsp90 ATPase AHSA1-like N-terminal domain-containing protein
Sequence:
MTNQSDAIFPNILWAQRAELVLITIPLQDATNVVVEIKEGRVLHFEAEAGGEKYRCDVELFREVVSEESRHAAQPRQIDIQLRKKAPLTESGEEEFAQSRSWLRLTRDKSKNSHIQVDWSRWRDEDEDEDETGGLGMDYNDLMSRMMTQKGLGEDDCMDCGNHTDEDGVGPGADKANHSDSDDYDDLPPLEP
Protein: Poly(A)-specific ribonuclease PARN-like (EC 3.1.13.4) (Polyadenylate-specific ribonuclease-like protein) (Q8W4C3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: 3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs (By similarity).
Subcellular location: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
Interaction partners:
- Poly
- Uncharacterized CRM domain-containing protein At3g25440
- Exosome complex component RRP4 homolog
- mRNA-decapping enzyme subunit 2
- Pentatricopeptide repeat-containing protein At2g33680
- Pentatricopeptide repeat-containing protein At1g32415
- AT3g56680/T8M16_10
- Polyribonucleotide nucleotidyltransferase 2, mitochondrial
- Putative defensin-like protein 148
- Tetratricopeptide repeat protein SKI3
Sequence:
MQRRFLSSISATAGNTKTLNQGRWSVKQVKKSNFHVTLDEIRTSIDSSDFIALSLQNTGSYAAAWHRVSAIDTPQTSYLKAKYAAERYQILQFALCPFSLQGSKLTVHPYNFHLFPRDELKCGMPSYSFSCQASRLTAMAREGFDFNICIYEGISYLSRAQESASKFLSENPILADSVTVSSSPATVADTVFVGRIRSRVKNWRQSCIDSGSKTGDDDLVSSLRRLVLGSEQYGSRLCLTIDVCSERQVQLILEMLTEFSDDVVPLLVASKSRGTQAVRTVFMSSKEDKDLFKRELKDLEKEENRRVRGFREVVDFISSSQKPVVSQNYLSDFTSIHAKFLGPLPSNVDDFSSSLSSAFPNVVDLSQFMKEISPLSNISNLPAAMSSLNRFFAPVDVEVANQGCPVKLDEGHQSHGQNAVMISQLFAKLCTIQKSDLSTIQSNEDFQALASDEHANSVTSCSKNAGDENVKVWSKNSRRVSSENLVFIWGLGKKMTAAKLKNVLQKSHPVFAREFDVKYIDRSSAILVFWESGPSETFLSAVNNEEQLDGSLREMVAEGLRGAGYETYKRACRLGFWEADLAESLDKALESSDTDPDSDTKPSEIDWSNELAINFDEL
Protein: Nuclear receptor subfamily 0 group B member 1 (Nuclear receptor DAX-1) (Q61066)
Organism: Mus musculus (Mouse)
Function: Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P51843}. Cytoplasm {ECO:0000250|UniProtKB:P51843}. Note=Shuttles between the cytoplasm and nucleus. Homodimers exits in the cytoplasm and in the nucleus. {ECO:0000250|UniProtKB:P51843}.
Interaction partners:
- Steroidogenic factor 1
- Homeobox protein NANOG
- Steroid hormone receptor ERR2
- Nuclear receptor subfamily 5 group A member 2
- Sal-like protein 4
- Transcription factor CP2-like protein 1
- Nuclear receptor corepressor 2
- POU domain, class 5, transcription factor 1
- Nuclear receptor corepressor 1
- Wilms tumor protein homolog
Sequence:
MAGEDHPWQGSILYNLLMSAKQKHASQEEREVRLGAQCWGCACGAQPVLGGERLSGGQARSLLYRCCFCGENHPRQGGILYSMLTNARQPSVATQAPRARFGAPCWGCACGSAEPLVGREGLPAGQAPSLLYRCCFCGEEHPRQGSILYSLLTSAQQTHVSREAPEAHRRGEWWQLSYCTQSVGGPEGLQSTQAMAFLYRSYVCGEEQPQQISVASGTPVSADQTPATPQEQPRAPWWDASPGVQRLITLKDPQVVCEAASAGLLKTLRFVKYLPCFQILPLDQQLVLVRSCWAPLLMLELAQDHLHFEMMEIPETNTTQEMLTTRRQETEGPEPAEPQATEQPQMVSAEAGHLLPAAAVQAIKSFFFKCWSLNIDTKEYAYLKGTVLFNPDLPGLQCVKYIEGLQWRTQQILTEHIRMMQREYQIRSAELNSALFLLRFINSDVVTELFFRPIIGAVSMDDMMLEMLCAKL
Protein: Biglycan (Bone/cartilage proteoglycan I) (PG-S1) (Q9GKQ6)
Organism: Sus scrofa (Pig)
Function: May be involved in collagen fiber assembly.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Interaction partners:
- Aggrecan core protein
- Collagen type I alpha 1 chain
- Decorin
- Toll-like receptor 2
- Collagen type I alpha 2 chain
- Ribonuclease pancreatic
- Fibromodulin
- Ameloblastin
- Elastin
- Neurotrophic factor BDNF precursor form
Sequence:
MWPLWLLASLLALSQALPFEQKAFWDFTLDDGLPMLNDEEASGADSTSGIPDLDALPPTFSAMCPFGCHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISRSTRRPSAPDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDLKLLQVVYLHTNNITKVGVNDFCPVGFGVKRAYYNGISLFNN
Protein: Leucine-rich repeat transmembrane protein FLRT1 (Fibronectin-like domain-containing leucine-rich transmembrane protein 1) (Q9NZU1)
Organism: Homo sapiens (Human)
Function: Plays a role in fibroblast growth factor-mediated signaling cascades that lead to the activation of MAP kinases. Promotes neurite outgrowth via FGFR1-mediated activation of downstream MAP kinases. Promotes an increase both in neurite number and in neurite length. May play a role in cell-cell adhesion and cell guidance via its interaction with ADGRL1/LPHN1 and ADGRL3.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q6RKD8}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q6RKD8}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q6RKD8}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q6RKD8}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q6RKD8}. Cell junction, focal adhesion {ECO:0000250|UniProtKB:Q6RKD8}. Secreted {ECO:0000250|UniProtKB:Q6RKD8}. Cell projection, neuron projection {ECO:0000250|UniProtKB:Q6RKD8}. Cell junction {ECO:0000250|UniProtKB:Q6RKD8}. Note=In addition to its location at the cell membrane, colocalizes with FGFR1 in punctate perinuclear cytoplasmic vesicles. Detected along neurites and at contacts between neurite termini and other cells. Proteolytic cleavage gives rise to a shedded ectodomain. {ECO:0000250|UniProtKB:Q6RKD8}.
Interaction partners:
- Netrin receptor UNC5A
- Adhesion G protein-coupled receptor L1
- Adhesion G protein-coupled receptor L2
- Adhesion G protein-coupled receptor L3
- Fibronectin
- Fibroblast growth factor receptor 1
Sequence:
MVVAHPTATATTTPTATVTATVVMTTATMDLRDWLFLCYGLIAFLTEVIDSTTCPSVCRCDNGFIYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKARAAVVNVRGLMCQGPEKVRGMAIKDITSEMDECFETGPQGGVANAAAKTTASNHASATTPQGSLFTLKAKRPGLRLPDSNIDYPMATGDGAKTLAIHVKALTADSIRITWKATLPASSFRLSWLRLGHSPAVGSITETLVQGDKTEYLLTALEPKSTYIICMVTMETSNAYVADETPVCAKAETADSYGPTTTLNQEQNAGPMASLPLAGIIGGAVALVFLFLVLGAICWYVHQAGELLTRERAYNRGSRKKDDYMESGTKKDNSILEIRGPGLQMLPINPYRAKEEYVVHTIFPSNGSSLCKATHTIGYGTTRGYRDGGIPDIDYSYT
Protein: Serine/threonine-protein kinase stt7, chloroplastic (EC 2.7.11.1) (Q84V18)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Function: Serine/threonine protein kinase required for state transition by phosphorylating light-harvesting complex II outer antennae (LCHII). State transition plays a central role in response to environmental changes and allows to adjust to changing light conditions via the redistribution of light excitation energy between photosystem II (PSII) and photosystem I (PSI).
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000269|PubMed:12624266}.
Interaction partners:
Sequence:
MALAQRQVSCRIERSTGASTSQPVGSCLLVQRRPGQRRGVPARATPEFIDALSALVPNLPLEQIAAPCQVMKCGDIVYRSTLDPSLYNEAGFDEKTVALLAPVLAYLFLPPGVLPGAIDYYIRAPLKRKQTKAIDKNDIVLGKRLGTGGFGTVFKGELKEEGGVKTSIIIKKAKEFGEAEVWMNERMSRVAGHHVAEFVTAFDESLNVPLPAAAGKRAAPVQPTSPLDANSIWLVWVYEGDNTLSSLMERREWPYNLEPLLFGRELRAPRGPVRELVTIKEAFRQLVQAVAACHSVGIVHRDIKPANCIVSERDKKIKLIDLGAAADLRIGINYVPNEYLLDPRYAPPQQYIMSTQTPKPPPKPVAAFLSPILWTMEKPDRFDMYSCGITLLQMVFGHLRNDNALIAFNKRLQELKWDLPAWRREEEAKLPSAKGALAESLEAGFEALDADGGAGWDLLMRLLAYKPTDRPSAAAVLAHPWLTSAPGRTASLQHSLSGSFEATVSTAAAATSTALTAAGKSLGQAAKDAGLASMEEAILKVNQGALTEAQLMEELGLQEPAPVAPREGSQTIAWWQERQNELKARLVERREAMSESDPYGAAPSAMQVGSAINNARGGKGAKPTTPVKPTGPMAAAGAAAAAAAAAARVEAKVKVPNILGVKKPASGGGSNGRANGNGNGKAAPAKAANGNGSGNGNTNGNGNGAKQQLFGGLLGRKQQPVEEVQEEPEEEVEPEQETASKKERAFNLLGVFRR
Protein: Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H (EC 3.4.22.16); Cathepsin H heavy chain; Cathepsin H light chain] (P00786)
Organism: Rattus norvegicus (Rat)
Function: Important for the overall degradation of proteins in lysosomes.
Subcellular location: Lysosome.
Interaction partners:
- Apoptosis regulator Bcl-2
- BH3-interacting domain death agonist
- Bcl-2-like protein 1
- Napsin A aspartic peptidase, isoform CRA_a
- Pulmonary surfactant-associated protein B
- Surfactant protein C
Sequence:
MWTALPLLCAGAWLLSAGATAELTVNAIEKFHFTSWMKQHQKTYSSREYSHRLQVFANNWRKIQAHNQRNHTFKMGLNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPSSMDWRKKGNVVSPVKNQGACGSCWTFSTTGALESAVAIASGKMMTLAEQQLVDCAQNFNNHGCQGGLPSQAFEYILYNKGIMGEDSYPYIGKNGQCKFNPEKAVAFVKNVVNITLNDEAAMVEAVALYNPVSFAFEVTEDFMMYKSGVYSSNSCHKTPDKVNHAVLAVGYGEQNGLLYWIVKNSWGSNWGNNGYFLIERGKNMCGLAACASYPIPQV
Protein: Homeobox protein HMX3 (Homeobox protein H6 family member 3) (Homeobox protein Nkx-5.1) (Q504H8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Interaction partners:
- POU domain, class 3, transcription factor 3-B
Sequence:
MPETTQDTCASAKDSPFFIKNLLNSDSKPSKPKPILAPTKAGLDGSFSLSQVGEINFPRFELPTQRFALPAYLERASAWWYPYTLSASAHLHRTEAAQKARDSSPTTGTDRDSPELVLKSDPDAKDDEDDNKSGDEIVLEEGDTEDGKKEGGIDDWKKSDDGADKKPCRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLSHAAAQRIVRVPILYHENSASESTNTAGNVPVSQPLLTFPHPVYYSHPIVTSVPLLRPV
Protein: Probable glycerol-3-phosphate dehydrogenase 2 (EC 1.1.1.8) (P34517)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Dihydroxyacetone phosphate acyltransferase
- Probable glycerol-3-phosphate acyltransferase, mitochondrial
- Phospholipid/glycerol acyltransferase domain-containing protein
- Phospholipid/glycerol acyltransferase domain-containing protein
- Glycerol-3-phosphate dehydrogenase [NAD
- Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-2
- Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-1
- Phospholipid/glycerol acyltransferase domain-containing protein
- Phospholipid/glycerol acyltransferase domain-containing protein
- Phospholipid/glycerol acyltransferase domain-containing protein
Sequence:
MSSSRIPQCENSSRLSLSSIFRYFGTTSTIATMSPKKVTIIGSGNWGSAIARIVGSTTKSFPDEFDPTVRMWVFEEIVNGEKLSEVINNRHENIKYLPGKVLPNNVVAVTDLVESCEGSNVLVFVVPHQFVKGICEKLVGKIPADTQAISLIKGISFDKTNQGVSTEKRGGLKLISEEIKEILKIEVSVLMGANLAPEVANDNFCEATIGCKRKAEDGPLLKKLFHTDNFRINVVEDAHTVELCGALKNVVACAAGFTDGLGYGDNTKAAVIRLGLMETTKFVEHYYPGSNLQTFFESCGIADLITTCYGGRNRKVCEAFVKTGKSMAEVEKELLNGQSAQGPLTAEEVYLMMHKTGLDAKFPLFTAVHKICAGEMKPAELVDCLRNHPEHM
Protein: Partner and localizer of BRCA2 (Q3U0P1)
Organism: Mus musculus (Mouse)
Function: Plays a critical role in homologous recombination repair (HRR) through its ability to recruit BRCA2 and RAD51 to DNA breaks. Strongly stimulates the DNA strand-invasion activity of RAD51, stabilizes the nucleoprotein filament against a disruptive BRC3-BRC4 polypeptide and helps RAD51 to overcome the suppressive effect of replication protein A (RPA). Functionally cooperates with RAD51AP1 in promoting of D-loop formation by RAD51. Serves as the molecular scaffold in the formation of the BRCA1-PALB2-BRCA2 complex which is essential for homologous recombination. Via its WD repeats is proposed to scaffold a HR complex containing RAD51C and BRCA2 which is thought to play a role in HR-mediated DNA repair. Essential partner of BRCA2 that promotes the localization and stability of BRCA2. Also enables its recombinational repair and checkpoint functions of BRCA2. May act by promoting stable association of BRCA2 with nuclear structures, allowing BRCA2 to escape the effects of proteasome-mediated degradation. Binds DNA with high affinity for D loop, which comprises single-stranded, double-stranded and branched DNA structures. May play a role in the extension step after strand invasion at replication-dependent DNA double-strand breaks; together with BRCA2 is involved in both POLH localization at collapsed replication forks and DNA polymerization activity (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q86YC2}. Note=Colocalizes with BRCA2 in nuclear foci. {ECO:0000250|UniProtKB:Q86YC2}.
Interaction partners:
- Breast cancer type 1 susceptibility protein homolog
- Breast cancer type 2 susceptibility protein homolog
- DNA repair protein RAD51 homolog 3
- DNA repair protein RAD51 homolog 1
- Fanconi anemia group J protein homolog
- Kelch-like ECH-associated protein 1
- Fanconi anemia group D2 protein homolog
- BRCA1-associated RING domain protein 1
- Large ribosomal subunit protein bL21m
- E3 ubiquitin-protein ligase RNF168
Sequence:
MEELSGKPLSYAEKEKLKEKLAFLKKEYSRTLARLQRAKRAEKAKNSKKAIEDGVPQPEASSQLSHSESINKGFPCDTLQSNHLDEETGENISQILDVEPQSFNCKQGKEVLHTPRAGDIQGQLLHSTSSPDGKKEQNTLPGTTKTPWEKSSVSQEKEDYFDTNSLALLGKHRKGQESISRKNSRTPVSEKTHLLSLRSQIPDPPALVTGIGEGILIPPSGKSERGIDTLVRGNTVSAEAAVPSCTASNSNHSQHLEHTPPKSGCKITTQGPASSTNLVAQDQKMTIFTVNSVVYKAVRAHGQLPGSPNSCSVNDLTHSNLPANSTPNSKSLKSPSNTVDERNEPLQEDEILGPSKNFNLAAVSPPSTESQIHSCTMLEGLLFPAEYYVRTTRRMSDCQRKIALEAVIQSHLGVKKKELKKKTKATKAVVLSSEDTDQSESGMLDTSTGQSSSGSLSQKLLSPAEVSSPPGPAGKATTPPPGRGHRGKRKSARTSTLGHCQLLFPPCAALAVNRSKGKFTKHKCQNRGVVIHDFELPDEDFGLLKLEKLKSCSEKLIESPDSKNCGERLPREGNHAALEELQRDSETEGLEEELTVPPGEAYRPGPTLRRQPGSKDLSSSIVLFTPADTAAPNDSGRPPPSLCSPAFPILGMTPALGSQAAGETLSTEAAQPCSTSQPPLLGDTNSLVNNSKQCNSSACSPKPDTNLQASGRQGQPACDSDSGPQATPLPVESFTFRENQLCGNACLELHEHSTEQTETADRPACDNLNPGNLQLVSELKNPSSSCSVDVSAMWWERAGAKEPCIVTACEDVVSLWKPLNSLQWEKVHTWHFTEVPVLQIVPVPDVYNLICVALGSLEIREIRALLCSSGDDSEKQVLLKSGDIKAMLGLTKRRLVSSTGTFCNQQIQIMTFADDGSSKDEQLLMPPDETVLTFAEVQGTQEALLGTTTVNSIVIWNLKTGQLLKKMHIDDSYQASVCHGAYSEKGLLFVVVSQPCAKESQALGSPVFQLLVINPKTAQSVGVLLCSLPQGQAGRFLEGDVKDHVAAAVLTSGTIAIWDLLLGHCTALLPPVSDQSWSLVKWSGTDSHLLAGQKDGNIFIYRYF
Protein: Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Zgc:158179 protein) (A4IFW3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MSSARARFFFIIFIFIQSAAGFRVQLQDGVRMLMSLDDGDIGPGVSEYAVRVSGEPLTHTLLFQQAADAHTLPEPLLFNASYHGLLYSISLMTDGRTHTTRSIITQPLPLDSVEMWDYAPSPETAVVFQIRSPDRNIFTRVNISYTEGHQRRYMLYKDFLHGKTVFKHWLSGVCYSNITFQLISEASVNRSALLSRSDITHNPQQHRTVPNPPLNVSLKILHLSGRGPPGPVLTGAILKNSHNASVVRRERDLPEYEEQEPTSDTLNTESNLTHTQLNQSESENESESEPVTAEPTLNSSTQSLWAWQTVSPAPTEEEEEGFVNALVPEYEDSNEPGSALGIPLEPAVMPAVMPTPLAPVLLQLRWSPPAPHTAYDAFNIYIYRNGNSTETATVDENTHEFLAELSESGTYRIHVTTLSSAGDCEARESSANTAFTFYLSPSGEWMEQPQERPQAVSVKMLDSSTAAVSWAPSTHTYNGSLISVQSLTCLRPSISQRMELNYCSEENITSDIISSLTPGAQYRVVVYHTNGPLVSPASEPVIIDIEPTGVRDLVVYPLSPSAVILSWQRPYNVAFRKYVLQTFFFNSATQTAQWSTYYEIAATASVIASVRVTDLLPAWFYNFRVTMVTWGDPPLSCCDTSTVSFITAPEAPHISSVEFSHGSVFVRWTYGDLFTDLTHSRMLHWQVVAEGKKSARRRFSVDVTRSVMKASLALPAGDIYNLTVTACTERSCNTSAPHIMKLDPAPPRSLYAVNASDTSVTLIWAEEGVVDHYLITCRALGAHAEQKKVREPLVTSAHVLTVSGLQASTTYNCSVRSSSYSSSSDPVHITVSTTVREMNPSVAAISALAVLSVLLISLLVLFLLVLRKKHMELSRECGAETFVNFASFERDGKLPYNWRRSLFAFLTLLPSCLWTDYLLAFYINPWSKTALKKRKLTSPVQLSDFEAYLKDMGKDSAYKFSLQFEELKSVGLDLSHEAADLPINRPKNRYTNILPYDFSRVKLISLHNDEGSDYINANYIPGYNSPREYIATQGPLPDTRNDFWKMVLQQKVHIIVMLTQCNERRRVKCDHYWPFSDEPVAYGEISVEMLAETDSPEWTIRSFRLAYADETQDVLHFNYTSWPDHGVPTVNAIESILQFVQIVRQQVNRSKGPIVVHCSAGVGRTGTFISLDRLMQHIQEHEYVDVLGLVSDMRSHRLSMVQTEEQYVFIHQCVLLMWKKKKQQSHTSDVIYENVSKS
Protein: PTPRF interacting protein alpha 1 (D3ZZ81)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MMCEVMPTISEAEGPPGGGGSHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNSQKKALTEGMLDGNHEQENAPSTNGKRSSDGSLSHEDLAKVLELQEVIDRQAREQSQMKERLASLSSHAAELEEDLDTARKDLIKSEEMNTKLQREVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVENAKKQLEETQHDKDQLVLNIEALKAELEQMRLRGSSLHHGRPHLGSVPDFRFSVADGHVDAYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDVDVSDGEDDRDTLLSSVDLLSPSGQADAQTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDNLGRFRSMSSIPPYPASSLAGSSPPGSGRSTPRRVPHSPAREVDRLGVMTLLPASREEVRDDKTTIKCETSPPSSPRPLRLDRLHKGALHTVSHEDIRDLRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGPLGKESPGQAGVSETENSSQDALGLSKLGGQAEKNRKLQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQNETRDVLVWSNDRVIRWILSIGLKEFANNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLLVTGTDRRFDEDDDKSFRRAPSWRKKFRPKDIRGLASGSAETLPANFRVTSSMSSPSMQPKKVQMDVYPHYFYR
Protein: Uncharacterized protein (F4IS02)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MENVVVVRDGDEELSLFLEMRRREKLQGVSSLSQPGANSVEKTSTKSLELLKTSCVKLRRSSVEKFLDSENDKSDYEWLLAAPEITLLGGKENSMVKLKEPKAKSTALKQREPLTRSVKVSKPTPRTVSSKQANTAAEVKPSIKPSRQATPTSRATLPSTRLTNSAQKSNSESITTSIKSNTRASAFPRSSSVGKSVSSAKCTTPKIPETRARPVSTSRSRVYSSGDRSTGRSKISNDVNPVLMGTQMVERVVNMRKLPPPKHDDNTTLGFGRTLSRSSLDMALRHMNIRHSVSKNLRVTVSASTNSMDKNESS
Protein: Fatty-acid-binding protein 1 (AtFAP1) (Chalcone-flavanone isomerase family protein 1) (Q9M1X2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Fatty-acid-binding protein. Interacts preferentially with saturated fatty acid. May be involved in alpha-linolenic (C18:3) metabolism.
Subcellular location: Plastid, chloroplast stroma {ECO:0000269|PubMed:22622584}.
Interaction partners:
- Fatty-acid-binding protein 3, chloroplastic
- Probable chalcone--flavanone isomerase 3
- AT3g52230/F4F15_340
- Sequence-specific DNA binding transcription factor
- YlmG homolog protein 1-2, chloroplastic
- Protein KINASE OF THE OUTER CHLOROPLAST MEMBRANE 1
- UDP-glycosyltransferase 91A1
- Alpha/beta-Hydrolases superfamily protein
- Protein RER1B
- Tetratricopeptide repeat
Sequence:
MVSFRFPFSFSQPPRATTSFSGFSISAVAVSVTVGAAAAGAAIAASRNPSHPILEWAFSSHRSSLSPWGSITLADESVVEPKTGFSFPASIGDSRRLLGVGLRKKSLLGLKNIDVYAFGVYADCDDVKKLVGDKYANLPASEIRGNKSFMDDLMEADIKMTIRLQIVYGKLNIRSVRNAFQESVGNRLKKFGGSDNDELLQSFTSLFKDEYKIPRNSTIDLTKDPGHVLSVAIEGNHVGSVKSHLLCRSILDLYIGEEPFDKNAREDFLDNAASLAFDN
Protein: Exosome complex component rrp4 (Ribosomal RNA-processing protein 4) (Q09704)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and in RNA surveillance pathways, preventing translation of aberrant mRNAs. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. rrp4 as peripheral part of the Exo-9 complex is thought to stabilize the hexameric ring of RNase PH-domain subunits (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Exosome complex component rrp42
- Exosome complex exonuclease dis3
- Exosome complex component rrp45
- Exosome complex component rrp46
- Exosome complex component mtr3
- Exosome complex component csl4
- Exosome complex component ski6
- Exosome complex component rrp40
- Exosome complex protein C1739.07
- Exosome complex component rrp43
Sequence:
MVTILKPEEFYVSSEADIVNDVSMTEMEDEIMEDEQMGLVDGEDVLEEFDKSIHQNLVTPGQLVTDDPQFMRGHGTYFEDGGIYASVAGSVQRVNKLISVKPLRSKYVPEIGDLIIGKIAEVQPKRWKVDIGAKQNAVLMLSSINLPGGIQRRKLETDELQMRSFFQEGDLLVAEVQQYFSDGSVSIHTRSLKYGKLRNGVFLKVPPALVVRSKSHAYALAGGVDIILSVNGYVWVSKHNENQHSSVSITRLEEEASESIYSNENDEIDGYTRLNISRVSICIKGLASRSLPLTQASITNFYESSLVFSNLQDLTVPKNMDQIAMEAMQ
Protein: Treacle ribosome biogenesis factor 1 (A0A3B3IS06)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESP
Protein: Sodium/hydrogen exchanger 1 (Na(+)/H(+) exchanger 1) (NHE-1) (Q68KI4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts in low affinity electroneutral exchange of protons for cations such as Na(+) or K(+) across membranes. Can also exchange Li(+) and Cs(+) with a lower affinity. Involved in vacuolar ion compartmentalization necessary for cell volume regulation and cytoplasmic Na(+) detoxification. Required during leaves expansion, probably to stimulate epidermal cell expansion. Confers competence to grow in high salinity conditions.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:10455050}; Multi-pass membrane protein {ECO:0000269|PubMed:10455050}. Endoplasmic reticulum membrane {ECO:0000305|PubMed:10455050}; Multi-pass membrane protein {ECO:0000305|PubMed:10455050}. Golgi apparatus membrane {ECO:0000305|PubMed:10455050}; Multi-pass membrane protein {ECO:0000305|PubMed:10455050}. Note=Tonoplast. Possibly also present in endoplasmic reticulum (ER) and Golgi apparatus.
Interaction partners:
- Sodium transporter HKT1
- Calcineurin B-like protein 4
- CBL-interacting serine/threonine-protein kinase 24
- Probable calcium-binding protein CML18
- Pyrophosphate-energized vacuolar membrane proton pump 1
- Delta-1-pyrroline-5-carboxylate synthase A
- Calcineurin B-like protein 10
- Cation/H
- Vacuolar cation/proton exchanger 1
- K
Sequence:
MLDSLVSKLPSLSTSDHASVVALNLFVALLCACIVLGHLLEENRWMNESITALLIGLGTGVTILLISKGKSSHLLVFSEDLFFIYLLPPIIFNAGFQVKKKQFFRNFVTIMLFGAVGTIISCTIISLGVTQFFKKLDIGTFDLGDYLAIGAIFAATDSVCTLQVLNQDETPLLYSLVFGEGVVNDATSVVVFNAIQSFDLTHLNHEAAFHLLGNFLYLFLLSTLLGAATGLISAYVIKKLYFGRHSTDREVALMMLMAYLSYMLAELFDLSGILTVFFCGIVMSHYTWHNVTESSRITTKHTFATLSFLAETFIFLYVGMDALDIDKWRSVSDTPGTSIAVSSILMGLVMVGRAAFVFPLSFLSNLAKKNQSEKINFNMQVVIWWSGLMRGAVSMALAYNKFTRAGHTDVRGNAIMITSTITVCLFSTVVFGMLTKPLISYLLPHQNATTSMLSDDNTPKSIHIPLLDQDSFIEPSGNHNVPRPDSIRGFLTRPTRTVHYYWRQFDDSFMRPVFGGRGFVPFVPGSPTERNPPDLSKA