wanglab/gogpt-training-data huggingface dataset:
Protein: Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein) (Q96Q42)
Organism: Homo sapiens (Human)
Function: May act as a GTPase regulator. Controls survival and growth of spinal motoneurons (By similarity).
Interaction partners:
- Ras-related protein Rab-5A
- Serine/threonine-protein kinase Nek1
- Probable helicase senataxin
- Superoxide dismutase
- GTPase-activating protein and VPS9 domain-containing protein 1
- Vesicle-associated membrane protein-associated protein B/C
- Polyphosphoinositide phosphatase
- TAR DNA-binding protein 43
- RNA-binding protein FUS
- Guanine nucleotide exchange factor C9orf72
Sequence:
MDSKKRSSTEAEGSKERGLVHIWQAGSFPITPERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSFGTLPWRSGPVEICPSSPILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAVRILQLACGEEHTLALSISREIWAWGTGCQLGLITTAFPVTKPQKVEHLAGRVVLQVACGAFHSLALVQCLPSQDLKPVPERCNQCSQLLITMTDKEDHVIISDSHCCPLGVTLTESQAENHASTALSPSTETLDRQEEVFENTLVANDQSVATELNAVSAQITSSDAMSSQQNVMGTTEISSARNIPSYPDTQAVNEYLRKLSDHSVREDSEHGEKPVPSQPLLEEAIPNLHSPPTTSTSALNSLVVSCASAVGVRVAATYEAGALSLKKVMNFYSTTPCETGAQAGSSAIGPEGLKDSREEQVKQESMQGKKSSSLVDIREEETEGGSRRLSLPGLLSQVSPRLLRKAARVKTRTVVLTPTYSGEADALLPSLRTEVWTWGKGKEGQLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTTVPRLAKISSENGVWSIAAGRDYSLFLVDTEDFQPGLYYSGRQDPTEGDNLPENHSGSKTPVLLSCSKLGYISRVTAGKDSYLALVDKNIMGYIASLHELATTERRFYSKLSDIKSQILRPLLSLENLGTTTTVQLLQEVASRFSKLCYLIGQHGASLSSFLHGVKEARSLVILKHSSLFLDSYTEYCTSITNFLVMGGFQLLAKPAIDFLNKNQELLQDLSEVNDENTQLMEILNTLFFLPIRRLHNYAKVLLKLATCFEVASPEYQKLQDSSSCYECLALHLGRKRKEAEYTLGFWKTFPGKMTDSLRKPERRLLCESSNRALSLQHAGRFSVNWFILFNDALVHAQFSTHHVFPLATLWAEPLSEEAGGVNGLKITTPEEQFTLISSTPQEKTKWLRAISQAVDQALRGMSDLPPYGSGSSVQRQEPPISRSAKYTFYKDPRLKDATYDGRWLSGKPHGRGVLKWPDGKMYSGMFRNGLEDGYGEYRIPNKAMNKEDHYVGHWKEGKMCGQGVYSYASGEVFEGCFQDNMRHGHGLLRSGKLTSSSPSMFIGQWVMDKKAGYGVFDDITRGEKYMGMWQDDVCQGNGVVVTQFGLYYEGNFHLNKMMGNGVLLSEDDTIYEGEFSDDWTLSGKGTLTMPNGDYIEGYFSGEWGSGIKITGTYFKPSLYESDKDRPKVFRKLGNLAVPADEKWKAVFDECWRQLGCEGPGQGEVWKAWDNIAVALTTSRRQHRDSPEILSRSQTQTLESLEFIPQHVGAFSVEKYDDIRKYLIKACDTPLHPLGRLVETLVAVYRMTYVGVGANRRLLQEAVKEIKSYLKRIFQLVRFLFPELPEEGSTIPLSAPLPTERKSFCTGKSDSRSESPEPGYVVTSSGLLLPVLLPRLYPPLFMLYALDNDREEDIYWECVLRLNKQPDIALLGFLGVQRKFWPATLSILGESKKVLPTTKDACFASAVECLQQISTTFTPSDKLKVIQQTFEEISQSVLASLHEDFLWSMDDLFPVFLYVVLRARIRNLGSEVHLIEDLMDPYLQHGEQGIMFTTLKACYYQIQREKLN
Protein: Homeobox protein MSH-C (Q01703)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Involved in the development of the inner ear.
Subcellular location: Nucleus.
Interaction partners:
Sequence:
MAPLSSMMNSLQGPLSQEGKLQERKSDKEDAQSNDKAAVKGCKGKALSLPFSVESLISDRTSSRTLYTSSEAGIISPTSGADERLKLSPMALYADRKIPVESVSNLSDCKRGDMEELSDKGQSGWFQTTSYTSPPRHSSPPPCTLRKHKNNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSNSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKLATKPLLPAFAFPFPLGTHVGSPPLYGPSSSFPRPALPVPGLFGGPVTYGMYYLS
Protein: Diacylglycerol kinase (DAG kinase) (EC 2.7.1.107) (Q7JNZ1)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MAAEGHNVDANLVDMRPNHGHYFVKKTFGKPAYCHHCCDKIWGMLTTGYSCEMCNFVCHEKCLRTVVSYCSSVALQLIKNPVAHTWSAPCLIKRKYCCVCRKRTDDALSVECEVCEYYVHVDCSDLAVSDCKEAATYVANMESANTVQYHHMREGNLPKESKCIVCRKTCFSTECLAGMRCEWCGQTAHAVCYRQMDKECDFGVLRKIMLPPMCLTIPRTELPMEQLLNISSHDQPQSLSSPSKIQADDVSTSGEDVKEREDFEIIRVFDGNNSYRSQISRNIVVAKHVSVQQVRDAALRRFHINDTPERYYITQVVGEVEEEILEDPVPLRNVKRPEGKRAQIFIRYYDDPDKDEVKVYGGWLRKVPVTFCAISVSKDTVVQDLVTDALYHFGLDGSCWNRYNLIEVSLDRGVAERTCNPQENVLQLVRNLRKDSLRRYHVVRFYVQEKEDPHDHAVFVGNLPVSLAQRQYERILLKLLGAKEKPFTAIGPIYFEYGSLIITFNTPKAATAAVQKLQSAIYEEKKLIVLCLPNVQPQMIPKDVEPLLVLVNVKSGGCQGTELIQSFRKLLNPFQVFDVLNGGPLVGLYVFRNIPKYKILACGGDGTIGWVLQCLDIAKQDAACFSPPCGIVPLGTGNDLARVLRWGGGYTGEENPMDILKDVIEADTVKLDRWAVVFHEEERNQPTSSGNQTEMNEQTMNNPEDQTSMIIMNNYFGIGIDADVCLKFHNKRDANPEKFQSRLFNKTQYAKIGLQKMFFERTCKDLWKRIELEVDGRIIELPNIEGIVVLNLLSWGSGANPWGTSKEEGNFSKPTHYDGLLEVVGISDVSRLGLIQSKLAAGIRIAQGGSIRITTHEEWPVQVDGEPHIQPPGTITILKSALKAQMLKKAKKSRRGGATNATSLTHPHPETSESMSGPLGVPSTLGDPNHGKTTPDNTAADSDEEGDAFL
Protein: Exonuclease 1 (hExo1) (EC 3.1.-.-) (Exonuclease I) (hExoI) (Q9UQ84)
Organism: Homo sapiens (Human)
Function: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.
Subcellular location: Nucleus {ECO:0000269|PubMed:11429708, ECO:0000269|PubMed:14676842, ECO:0000269|PubMed:17426132}. Note=Colocalizes with PCNA to discrete nuclear foci in S-phase.
Interaction partners:
- DNA mismatch repair protein Msh2
- DNA mismatch repair protein Mlh1
- RecQ-like DNA helicase BLM
- Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN
- DNA replication ATP-dependent helicase/nuclease DNA2
- DNA repair protein RAD51 homolog 1
- DNA mismatch repair protein Msh6
- Mismatch repair endonuclease PMS2
- DNA endonuclease RBBP8
- DNA mismatch repair protein Mlh3
Sequence:
MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFTRSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITEDSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCDYLSSLRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNAYEDDVDPETLSYAGQYVDDSIALQIALGNKDINTFEQIDDYNPDTAMPAHSRSHSWDDKTCQKSANVSSIWHRNYSPRPESGTVSDAPQLKENPSTVGVERVISTKGLNLPRKSSIVKRPRSAELSEDDLLSQYSLSFTKKTKKNSSEGNKSLSFSEVFVPDLVNGPTNKKSVSTPPRTRNKFATFLQRKNEESGAVVVPGTRSRFFCSSDSTDCVSNKVSIQPLDETAVTDKENNLHESEYGDQEGKRLVDTDVARNSSDDIPNNHIPGDHIPDKATVFTDEESYSFESSKFTRTISPPTLGTLRSCFSWSGGLGDFSRTPSPSPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESSDDESHPLREEACSSQSQESGEFSLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTSKLRLSHFSKKDTPLRNKVPGLYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHNAENKPGLQIKLNELWKNFGFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRVQRAIFQ
Protein: rRNA-processing protein EFG1 (Exit from G1 protein 1) (Q3E705)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in rRNA processing. Required growth at elevated temperatures, resistance to hydroxyurea and for cell cycle progression.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Essential nuclear protein 1
- ATP-dependent RNA helicase FAL1
- Nucleolar protein 9
- Protein SOK2
- KRR1 small subunit processome component
- U3 small nucleolar RNA-associated protein 7
- Nucleolar complex protein 14
- Protein LTV1
- Dimethyladenosine transferase
- Bud site selection protein 22
Sequence:
MAKLQRKRSKALGSSLEMSQIMDAGTNKIKRRIRDLERLLKKKKDILPSTVIIEKERNLQALRLELQNNELKNKIKANAKKYHMVRFFEKKKALRKYNRLLKKIKESGADDKDLQQKLRATKIELCYVINFPKTEKYIALYPNDTPSTDPKGVELTNLRREQFLKLVAERMDANTLNVSFEEILKGKKLDEDSIGLTLSPDKDHEDGSQVSPTQDRKELDQVVGEDEKDDFFE
Protein: 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4) (P07639)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00110}.
Interaction partners:
- Quinate/shikimate dehydrogenase
- Shikimate kinase 2
- Shikimate kinase 1
- 3-phosphoshikimate 1-carboxyvinyltransferase
- Chorismate synthase
- Shikimate dehydrogenase
- 3-dehydroquinate dehydratase
- Phospho-2-dehydro-3-deoxyheptonate aldolase, Tyr-sensitive
- Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive
- Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive
Sequence:
MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLKRAGLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNAIADCQSA
Protein: Arrestin domain-containing protein C (Q55CH0)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Arrestin domain-containing protein A
- Arrestin domain-containing protein D
Sequence:
MTQRSLKINIIEGKDLKGLDSGGVSDCYVKFKCGPISAKTEVIKKSTSPIWNYMINIGNVEENTLLQFECFDWERIGNNRTMGKTQAFVSDLSSGAKRNLMDQWLRLDTKGFIRISYEFTPPYPLETESTNSPNLSVVGNGSSSSSSLMYNPTPVYFKPIFLPTIPSETINNNKSTTCHFLIPGSVYQTRPFVCGEFVNCSLVLNVFEARIVVRSLNLSFSGSITYKGKKQRKLVNDYRDLLLGFTGGVPVPNNNGNNNLTSNKVVLERGKHVFPFQFFIDKTCKSTVNLTDYKVNYYLSFHADIVNQPDISASQEIKVVNLEDTVYKQTISPINAQTSKSPLTGGNISISCKSVKNSFYPGEEIELEVEVNNSSKKKIKNVDIQLNKVEYDGTDVTGTSYQLLTMTKKFYPKIKQNTACKQMVVIELPSTTQCVGLIHSIAETKMIRVEYHLLVNLDIPSCVDLRLKLPITIVQPDPKFETLPNPLTEIGNLPRYVKDWSIKNFHSWVLFKKQCPDVMALNPEFYQYNLSGSDLMQLPTETLYSIFKGAGPRTQELVNDLQSQIFEIKLVRNFLKELQLSNLIDYFEKQTITWDILLQLNYNEIFSITDITIGDAKRIFLKIQQIQSERQKQQEQQEQQVVSNLEAVSLQKSE
Protein: LD10950p (Q86NT0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MLLKFTKTSGAGPSAVPLLTTAPATVTSSASMQATTTSYAARGTGMRMTMSTNSTMSARIHRKGFRIPSKRQPGKGLPGKLHTITRTGPGKMVPGKRIPQRPHPPPCDNSNDSGLGFDQHTELRSSAGAGGVTDPAANGGSGSNSGQRSSLLVNSALTNTVAAAAAAAAAAVASNTLQQHQQHHQQQQQQQQQQQQQQQQQQQQQQQQQHSPQQHLIRAIPVSRFISARNVTRVANKRQPTTPLNSVASSNDGQVQLEILSQPEQQHRARYQTEGSRGAVKDRSGNGFPIVRLTGYDKVAVLQVFIGTDIGRVAPHMFYQACKVAGKNSTQCNEKKVDGTMVIEIDFKPETDMTITCDCVGILKERNVDVEHRFPEHLAQKNKKKSTRCRMVFRTQLTRDDGTTETLQVCSNPIICTQPPGVPEICKKSLNSCPVDGGLELFIIGKNFLKDTHVVFQETYDSVNGDDPATEIAVRQQLIGGTAALWEQSVLPDKEYLHQTHLICTVPPYLHQNILKPVQVQVSIVSSGKKSEPHTFTYTAKGQYTTLAAASTLSNTIHAQDVSGFMDTTSASNASGSSGWSAAGGSGNNTSTGDNVEAKHEIDSGMMPPPITTQIPMGVRRSSLPSVTPMITDQQLVHLNAVAASAEALKTELDDSNSHSPLTGESTPDSPNAALQYHRFARKPSLDTIMYDQSNSLPGFPTVVAPATAAAVAAAVDIDPTAVAVAVELAVKNEIVKHVVQQHQQMQEQMHEQQQQQQQQQQQQQQQQQQQPQQQQQQQVHKFIDELTKSTSVVSSNGTTEPALFTTSAVIDHALTDILQASLALRRPMWCWKGVCP
Protein: Tryptophan N-monooxygenase 2 (EC 1.14.14.156) (Cytochrome P450 79B3) (Tryptophan N-hydroxylase 2) (Q501D8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Converts tryptophan to indole-3-acetaldoxime, a precursor for tryptophan derived glucosinolates and indole-3-acetic acid (IAA).
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- L-tryptophan--pyruvate aminotransferase 1
- Cytochrome P450 83B1
- Tryptophan aminotransferase-related protein 2
- Tryptophan N-monooxygenase 1
- Tryptophan synthase beta chain 1, chloroplastic
- Tryptophan aminotransferase-related protein 1
- Indoleacetaldoxime dehydratase
- Cytochrome P450 71A12
- S-alkyl-thiohydroximate lyase SUR1
- Cytochrome P450 71A18
Sequence:
MDTLASNSSDLTTKSSLGMSSFTNMYLLTTLQALAALCFLMILNKIKSSSRNKKLHPLPPGPTGFPIVGMIPAMLKNRPVFRWLHSLMKELNTEIACVRLGNTHVIPVTCPKIAREIFKQQDALFASRPLTYAQKILSNGYKTCVITPFGEQFKKMRKVIMTEIVCPARHRWLHDNRAEETDHLTAWLYNMVKNSEPVDLRFVTRHYCGNAIKRLMFGTRTFSEKTEADGGPTLEDIEHMDAMFEGLGFTFAFCISDYLPMLTGLDLNGHEKIMRESSAIMDKYHDPIIDERIKMWREGKRTQIEDFLDIFISIKDEAGQPLLTADEIKPTIKELVMAAPDNPSNAVEWAIAEMINKPEILHKAMEEIDRVVGKERFVQESDIPKLNYVKAIIREAFRLHPVAAFNLPHVALSDTTVAGYHIPKGSQVLLSRYGLGRNPKVWSDPLSFKPERHLNECSEVTLTENDLRFISFSTGKRGCAAPALGTAITTMMLARLLQGFKWKLAGSETRVELMESSHDMFLSKPLVLVGELRLSEDLYPMVK
Protein: Ras homolog family member T1 (A0A0H2UHC7)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MAAACPGTAVPVWLSEEDLSCIICQGLLDWPTTLPCGHSFCLQCLKDLWVSKRAGVDSCPWACPICRKGPSAKPVLHKNPLLQDLVDKYRQAALELEAGPEPAPVPRSLCTPTPPQVTVQKSTTQVVQELTELVGQLVDIVKSLQTQRPSLASGLDNALGILHMDSSSEEEYPLDSPKLVTFSASQKKIQEILRDLEKIQETLQGSVTGNEAPKKQVEEMASSVGLLPDQRYPVSRKASQFSLWAISPTFDLRSLSCNLEVSNNCRMVTVSRALQPYHWSSERFSISQVLCSQAFSSGQKYWEVDTRNCSHWAVGVASWGMKRDKMLGRTMDSWCIEWRGPSQFSAWAMMKKTDLSSGPPEVVGVWLDLELGKLAFYSVADQERPLYECEVSSSSPLHPAFWLYGLTPGNYLEILQIYKIVHEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEETVCLQGRCSIHESVDVPKALVPRRTPSSSPPPPASAEPEEAELACPGSEAERQRRSRCRRSWRPRFRRRGLRADIIGKHSRVGKTSLIMSLVSEEFPEEVNM
Protein: Kelch-like protein 41 (Kel-like protein 23) (Kelch repeat and BTB domain-containing protein 10) (Kelch-related protein 1) (Sarcosin) (Q9ER30)
Organism: Rattus norvegicus (Rat)
Function: Involved in skeletal muscle development and differentiation. Regulates proliferation and differentiation of myoblasts and plays a role in myofibril assembly by promoting lateral fusion of adjacent thin fibrils into mature, wide myofibrils. Required for pseudopod elongation in transformed cells.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10713668}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10713668}. Cell projection, pseudopodium {ECO:0000269|PubMed:10713668}. Cell projection, ruffle {ECO:0000269|PubMed:10713668}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000250|UniProtKB:A2AUC9}. Sarcoplasmic reticulum membrane {ECO:0000250|UniProtKB:O60662}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O60662}. Note=Predominantly cytoplasmic but can colocalize with F-actin at the membrane ruffle-like structures at the tips of transformation-specific pseudopodia.
Interaction partners:
- Cullin-3
- E3 ubiquitin-protein ligase RBX1
- Nebulin
- BBSome complex member BBS1
- Bardet-Biedl syndrome 9
- Kelch-like family member 40
- Kelch-like family member 9
- Leiomodin-3
- Katanin p60 ATPase-containing subunit A1
- Kelch-like protein 21
Sequence:
MDSQRELAEELRLYQSTLLQDGLKDLLEEKKFIDCTLKAGDKSFPCHRLILSACSPYFREYFLSEIEEEKKKEMALDNVDPAILDLIIKYLYSASIDLNDGNVQDIFALSSRFQIPSVFTVCVSYLQKRLAPGNCLAILRLGLLLDCPRLAISAREFVSDRFVQICKEEDFMQLSPQELISVISNDSLNVEKEEVVFEAVMKWVRTDKENRAKNLSEVFDCIRFRLMAEKYFKDHVEKDDIIKSNPEVQKKIKVLKDAFAGKLPEPSKSAEKGGTGEVNGDVGDEDLLPGYLNDIPRHGMFVKDLILLVNDTAAVAYDPMENECYLTALAEQIPRNHSSIVTQQNQVYVVGGLYVDEENKDQPLQSYFFQLDNVSSEWVGLPPLPSARCLFGLGEVDDKIYVVAGKDLQTEASLDSVLCYDPVAAKWSEVKNLPIKVYGHNVISHNGMIYCLGGKTDDKKCTNRVFIYNPKKGDWKDLAPMKTPRSMFGVAIHKGKIVIAGGVTEDGLSASVEAFDLKTNKWEVMTEFPQERSSISLVSLAGSLYAIGGFAMIQLESKEFAPTEVNDIWKYEDDKKEWAGMLKEIRYASGASCLATRLNLFKLSKL
Protein: UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (UGPase) (Q16851)
Organism: Homo sapiens (Human)
Function: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:31820119, ECO:0000269|PubMed:8354390}.
Interaction partners:
- UDP-glucose 4-epimerase
- Glycogen phosphorylase, liver form
- Phosphoglucomutase-1
- Glycogen phosphorylase, brain form
- Glycogen phosphorylase, muscle form
- Galactose-1-phosphate uridylyltransferase
- UDP-glucose 6-dehydrogenase
- Phosphopentomutase
- Glycogen [starch] synthase, muscle
- Glycogen [starch] synthase, liver
Sequence:
MSRFVQDLSKAMSQDGASQFQEVIRQELELSVKKELEKILTTASSHEFEHTKKDLDGFRKLFHRFLQEKGPSVDWGKIQRPPEDSIQPYEKIKARGLPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIYTFNQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKRCEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTLDGGLNVIQLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSSFTKVQDYLRRFESIPDMLELDHLTVSGDVTFGKNVSLKGTVIIIANHGDRIDIPPGAVLENKIVSGNLRILDH
Protein: Aminopeptidase 2, mitochondrial (AP-II) (Aminopeptidase II) (EC 3.4.11.-) (YscII) (P32454)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in the cellular supply of leucine from externally offered leucine-containing dipeptide substrates.
Subcellular location: Periplasm. Cytoplasm. Mitochondrion.
Interaction partners:
- DNA-
- Cysteine proteinase 1, mitochondrial
- Intermediate cleaving peptidase 55
- Vacuolar aminopeptidase 1
- Aminopeptidase Y
Sequence:
MPIVRWLLLKSAVRGSSLIGKAHPCLRSIAAHPRYLSNVYSPPAGVSRSLRINVMWKQSKLTPPRFVKIMNRRPLFTETSHACAKCQKTSQLLNKTPNREILPDNVVPLHYDLTVEPDFKTFKFEGSVKIELKINNPAIDTVTLNTVDTDIHSAKIGDVTSSEIISEEEQQVTTFAFPKGTMSSFKGNAFLDIKFTGILNDNMAGFYRAKYEDKLTGETKYMATTQMEPTDARRAFPCFDEPNLKASFAITLVSDPSLTHLSNMDVKNEYVKDGKKVTLFNTTPKMSTYLVAFIVAELKYVESKNFRIPVRVYATPGNEKHGQFAADLTAKTLAFFEKTFGIQYPLPKMDNVAVHEFSAGAMENWGLVTYRVVDLLLDKDNSTLDRIQRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNEFQPEWKVWEQYVTDTLQHALSLDSLRSSHPIEVPVKKADEINQIFDAISYSKGASLLRMISKWLGEETFIKGVSQYLNKFKYGNAKTEDLWDALADASGKDVRSVMNIWTKKVGFPVISVSEDGNGKITFRQNRYLSTADVKPDEDKTIYPVFLALKTKNGVDSSVVLSERSKTIELEDPTFFKVNSEQSGIYITSYTDERWAKLGQQADLLSVEDRVGLVADVKTLSASGYTSTTNFLNLVSKWNNEKSFVVWDQIINSISSMKSTWLFEPKETQDALDNFTKQLISGMTHHLGWEFKSSDSFSTQRLKVTMFGAACAARDADVEKAALKMFTDYCSGNKEAIPALIKPIVFNTVARVGGAENYEKVYKIYLDPISNDEKLAALRSLGRFKEPKLLERTLGYLFDGTVLNQDIYIPMQGMRAHQEGVEALWNWVKKNWDELVKRLPPGLSMLGSVVTLGTSGFTSMQKIDEIKKFFATKSTKGFDQSLAQSLDTITSKAQWVNRDRDVVNKYLKENGYY
Protein: Basic leucine zipper 34 (AtbZIP34) (bZIP protein 34) (F4IN23)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional activator involved in the sporophytic control of cell wall patterning and gametophytic control of pollen development. May play a role in the control of metabolic pathways regulating cellular transport and lipid metabolism.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:17719007}.
Interaction partners:
- Basic leucine zipper 9
- Basic leucine zipper 19
- Basic leucine zipper 8
- Basic-leucine zipper
- Basic leucine zipper 1
- TRF-like 8
- Basic leucine zipper 43
- Transcription factor TGA10
Sequence:
MAQLPPKIPNMTQHWPDFSSQKLSPFSTPTATAVATATTTVQNPSWVDEFLDFSASRRGNHRRSISDSIAFLEAPTVSIEDHQFDRFDDEQFMSMFTDDDNLHSNPSHINNKNNNVGPTGSSSNTSTPSNSFNDDNKELPPSDHNMNNNINNNYNDEVQSQCKMEPEDGTASNNNSGDSSGNRILDPKRVKRILANRQSAQRSRVRKLQYISELERSVTSLQAEVSVLSPRVAFLDHQRLLLNVDNSALKQRIAALSQDKLFKDAHQEALKREIERLRQVYNQQSLTNVENANHLSATGAGATPAVDIKSSVETEQLLNVS
Protein: 60 kDa heat shock protein, mitochondrial (E7EXB4)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDR
Protein: N-succinylarginine dihydrolase (EC 3.5.3.23) (P76216)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
Interaction partners:
- N-succinylglutamate 5-semialdehyde dehydrogenase
- Succinylglutamate desuccinylase
- Succinylornithine transaminase
- Arginine N-succinyltransferase
Sequence:
MNAWEVNFDGLVGLTHHYAGLSFGNEASTRHRFQVSNPRLAAKQGLLKMKALADAGFPQAVIPPHERPFIPVLRQLGFSGSDEQVLEKVARQAPHWLSSVSSASPMWVANAATIAPSADTLDGKVHLTVANLNNKFHRSLEAPVTESLLKAIFNDEEKFSVHSALPQVALLGDEGAANHNRLGGHYGEPGMQLFVYGREEGNDTRPSRYPARQTREASEAVARLNQVNPQQVIFAQQNPDVIDQGVFHNDVIAVSNRQVLFCHQQAFARQSQLLANLRARVNGFMAIEVPATQVSVSDTVSTYLFNSQLLSRDDGSMMLVLPQECREHAGVWGYLNELLAADNPISELKVFDLRESMANGGGPACLRLRVVLTEEERRAVNPAVMMNDTLFNALNDWVDRYYRDRLTAADLADPQLLREGREALDVLSQLLNLGSVYPFQREGGGNG
Protein: ATP-dependent protease subunit HslV (EC 3.4.25.2) (P43772)
Organism: Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00248}.
Interaction partners:
- ATP-dependent protease ATPase subunit HslU
- Chaperone protein DnaJ
- Chaperonin GroEL
- ATP-dependent Clp protease proteolytic subunit
- Protein GrpE
- Chaperone protein HtpG
- ATP-dependent Clp protease ATP-binding subunit ClpX
- Co-chaperonin GroES
- Lon protease
- Uncharacterized protein HI_1159
Sequence:
MTTIVSVRRNGQVVVGGDGQVSLGNTVMKGNARKVRRLYNGKVLAGFAGGTADAFTLFELFERKLEMHQGHLLKSAVELAKDWRTDRALRKLEAMLIVADEKESLIITGIGDVVQPEEDQILAIGSGGNYALSAARALVENTELSAHEIVEKSLRIAGDICVFTNTNFTIEELPN
Protein: Mediator of RNA polymerase II transcription subunit 33B (Protein REDUCED EPIDERMAL FLUORESCENCE 4) (AtREF4) (F4IN69)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Involved in the repression of phenylpropanoid biosynthesis. May compete with MED33B for common binding partners or for occupancy in Mediator.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 33A
- Mediator of RNA polymerase II transcription subunit 20a
- Mediator of RNA polymerase II transcription subunit 32
- Mediator of RNA polymerase II transcription subunit 8
- Mediator of RNA polymerase II transcription subunit 14
- Mediator of RNA polymerase II transcription subunit 23
- Mediator of RNA polymerase II transcription subunit 18
- Mediator of RNA polymerase II transcription subunit 16
- Mediator of RNA polymerase II transcription subunit 17
- Mediator of RNA polymerase II transcription subunit 15a
Sequence:
MAPSEFQPSLWESVTSLIRSAQEKNVDPLHWALQLRLTLASAGISLPSPDLAQFLVTHIFWENHSPLSWKLLEKAISVNIVPPLLVLALLSPRVIPNRKLHPAAYRLYMELLKRHAFSFMPLIRAPGYHKTMNSIDDILHLSETFGVQDQEPGSILLAFVFSIVWELLDASLDEEGLLELTSNKRSKWPSSPHDMDLDGLENSVKRNENHDALEKANTEMAIELIQEFLQNKVTSRILHLASQNMESKTIPRGEFHAIVSSGSKLALTSDSALWLPIDLFFEDIMDGTQAAAASAVENLTGLVKALQAANSTSWHDAFLALWLAALRLVQRENLCLRYCFFMHMLEILSEERDPIEGPVPRTDTFLCVLLSVTPLAVANIIEEEESQWIDQTSSSPSNQWKEKKGKCRQGLINSLQQLGDYESLLTPPRSVQSVANQAAAKAIMFISGITNSNGSYENTSMSESASGCCKVRFSLFTLKMFVVMGVYLLCNISCWSLVMKGSPLTPSLTNSLITTPASSLAEIEKMYEVATTGSEDEKIAVASILCGASLFRGWSIQEHVIIFIVTLLSPPAPADLSGSYSHLINSAPFLNVLLVGISPIDCVHIFSLHGVVPLLAGALMPICEAFGSGVPNITWTLPTGELISSHAVFSTAFTLLLRLWRFDHPPLDYVLGDVPPVGPQPSPEYLLLVRNCRLECFGKSPKDRMARRRFSKVIDISVDPIFMDSFPRLKQWYRQHQECMASILSELKTGSPVHHIVDSLLSMMFKKANKGGSQSLTPSSGSSSLSTSGGDDSSDQLKLPAWDILEAAPFVLDAALTACAHGSLSPRELATGLKILADFLPATLGTMVSYFSSEVTRGLWKPVSMNGTDWPSPAANLASVEQQIEKILAATGVDVPRLPADGISAATLPLPLAALVSLTITYKLDKATERFLVLVGPALDSLAAACPWPCMPIVTSLWTQKVKRWSDFLIFSASRTVFHHNRDAVIQLLRSCFTCTLGLTPTSQLCSYGGVGALLGHGFGSRYSGGISTAAPGILYIKVHRSIRDVMFLTEEILSLLMFSVKSIATRELPAGQAEKLKKTKDGSRYGIGQVSLSLAMRRVKLAASLGASLVWISGGLNLVQALIKETLPSWFISVHGEEDELGGMVPMLRGYALAYFAILSSAFAWGVDSSYPASKRRPRVLWLHLEFMVSALEGKISLGCDWATWQAYVTGFVSLMVQCTPAWVLEVDVEVIKRLSKSLRQWNEQDLALALLCAGGLGTMGAATELIVETCHQH
Protein: FZR1 protein (Fizzy and cell division cycle 20 related 1) (Fizzy-related protein homolog isoform 2) (Q5H7B9)
Organism: Sus scrofa (Pig)
Interaction partners:
- Anaphase-promoting complex subunit 4
- Anaphase-promoting complex subunit 5
- Cell division cycle protein 27 homolog
- Cell division cycle protein 23 homolog
- Anaphase-promoting complex subunit 7
- Anaphase-promoting complex subunit 2
- Serine/threonine-protein kinase PLK
- Mitotic spindle assembly checkpoint protein MAD2A
- Cell division cycle 16
- Serine/threonine-protein kinase Nek2
Sequence:
MDQDYERRLLRQIIIQNENTMPCVAEMRRTLTPANSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPERKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESVSVLNLFTRIR