wanglab/gogpt-training-data huggingface dataset:
Protein: Eyes absent homolog (EC 3.1.3.48) (A0A8I6B402)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEDTQDLNEQSVKKTCPESDVSEPQNSRSMEMQDLASPHALVGGSDTPGSSKLDKSGLSSTSVTTNGTGVSLLAVKTEPLHSSETTTTTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPAYDLGVMLPAIKTESGLPQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTSSSTSTYQLQESLQGLTSQPGEFDTVQSPSTPIKDLDDRTCRSSGSKSRGRGRKNNPSPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHATASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCVNVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIVSRFGTNITYVVIGDGRDEEHAANQHNMPFWRISSHSDLLALHQALELEYL
Protein: Vacuolar protein sorting-associated protein 52 homolog (SAC2 suppressor of actin mutations 2-like protein) (Q8N1B4)
Organism: Homo sapiens (Human)
Function: Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:15878329, ECO:0000269|PubMed:18367545}; Peripheral membrane protein. Endosome membrane {ECO:0000269|PubMed:18367545}; Peripheral membrane protein. Recycling endosome {ECO:0000269|PubMed:25799061}. Note=Localizes to the trans-Golgi network as part of the GARP complex, while it localizes to recycling endosomes as part of the EARP complex (PubMed:25799061). {ECO:0000269|PubMed:25799061}.
Interaction partners:
- Vacuolar protein sorting-associated protein 51 homolog
- Vacuolar protein sorting-associated protein 54
- Vacuolar protein sorting-associated protein 53 homolog
- Syndetin
- Conserved oligomeric Golgi complex subunit 3
- Conserved oligomeric Golgi complex subunit 6
- Syntaxin-16
- Ras-related protein Rab-6A
- Vesicle-associated membrane protein 4
- Syntaxin-6
Sequence:
MAAAATMAAAARELVLRAGTSDMEEEEGPLAGGPGLQEPLQLGELDITSDEFILDEVDVHIQANLEDELVKEALKTGVDLRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSSISSEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLVVPSALVTAILEAPVTEPRFLEQLQELDAKAAAVREQEARGTAACADVRGVLDRLRVKAVTKIREFILQKIYSFRKPMTNYQIPQTALLKYRFFYQFLLGNERATAKEIRDEYVETLSKIYLSYYRSYLGRLMKVQYEEVAEKDDLMGVEDTAKKGFFSKPSLRSRNTIFTLGTRGSVISPTELEAPILVPHTAQRGEQRYPFEALFRSQHYALLDNSCREYLFICEFFVVSGPAAHDLFHAVMGRTLSMTLKHLDSYLADCYDAIAVFLCIHIVLRFRNIAAKRDVPALDRYWEQVLALLWPRFELILEMNVQSVRSTDPQRLGGLDTRPHYITRRYAEFSSALVSINQTIPNERTMQLLGQLQVEVENFVLRVAAEFSSRKEQLVFLINNYDMMLGVLMERAADDSKEVESFQQLLNARTQEFIEELLSPPFGGLVAFVKEAEALIERGQAERLRGEEARVTQLIRGFGSSWKSSVESLSQDVMRSFTNFRNGTSIIQGALTQLIQLYHRFHRVLSQPQLRALPARAELINIHHLMVELKKHKPNF
Protein: Augmin complex subunit dgt4 (Dim gamma-tubulin 4) (Q9W4M8)
Organism: Drosophila melanogaster (Fruit fly)
Function: As part of the augmin complex, plays a role in centrosome-independent generation of spindle microtubules. The complex is required for mitotic spindle assembly through its involvement in localizing gamma-tubulin to spindle microtubules.
Subcellular location: Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:17412918, ECO:0000269|PubMed:18443220}.
Interaction partners:
- Augmin complex subunit msd1
- Augmin complex subunit dgt2
- Augmin complex subunit dgt5
- Augmin complex subunit dgt3
- Augmin complex subunit msd5
- Augmin complex subunit dgt6
- Augmin complex subunit wac
Sequence:
METPPTPTTTTPPSLTTEGTMDDIQYLLHLEAMRRFQEDSRNVKRQVEEQVRIWLDAKCEYQRDFGRLARLLKCGALQAAVDAHRVSDVNQVDQAAKDIASLRSKLGSDLRPAILDSNDVKQCLEHLNTTHKPRLNLCRQQREFAQNQEALRSLRTAVDGLENGMEMGMIQAMDRLVEDLLPPRETNN
Protein: Transcription factor otaR1 (Ochratoxin A biosynthesis cluster protein R1) (A0A1R3RGK4)
Organism: Aspergillus carbonarius (strain ITEM 5010)
Function: Transcription factor; part of the gene cluster that mediates the biosynthesis of ochratoxin A (OTA), a mycotoxin demonstrated to have nephrotoxic, immunotoxic, genotoxic, neurotoxic, and teratogenic properties. Positively regulates the expression of the cluster genes otaA, otaB, otaC and otaD, and the subsequent production of OTA.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
Interaction partners:
- BZIP domain-containing protein
- RING-type domain-containing protein
- Kinetochore protein SPC25
- Kinetochore protein NDC80
Sequence:
MEPALISPELLDGSSLLPHSSADESSSTGLSLGSLLSSSNDLSSETSMPQFEQLERMLGSPTIANHVDFTTQSTDLGFLSDPNITLSSIELTELFSIPSDNASLMPEPSRQPSPLKAPDLQTTPPATGLIDSEANPTSVPLGNSVEQSADVKQLRKKYHEKYKERNRVAAGKSRQKQVDLIELLQAEQREEERRRKALERELSQIHKELLDLKQELQHHIRIANCMTMMSHGAHMQTLGLLAQDMLR
Protein: Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PP2A-beta) (EC 3.1.3.16) (Q0P594)
Organism: Bos taurus (Bovine)
Function: Catalytic subunit of protein phosphatase 2A (PP2A), a serine/threonine phosphatase involved in the regulation of a wide variety of enzymes, signal transduction pathways, and cellular events. PP2A can modulate the activity of phosphorylase B kinase, casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P62714}. Nucleus {ECO:0000250|UniProtKB:P62714}. Chromosome, centromere {ECO:0000250|UniProtKB:P62714}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250|UniProtKB:P62714}. Note=In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles. {ECO:0000250|UniProtKB:P62714}.
Interaction partners:
- Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
- Protein phosphatase 2 scaffold subunit Abeta
- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B
- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B
- IGBP1 protein
- IGBP1 protein
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit
- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit
Sequence:
MDDKAFTKDLDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL
Protein: Carboxypeptidase N subunit 2 (Carboxypeptidase N 83 kDa chain) (Carboxypeptidase N large subunit) (Carboxypeptidase N polypeptide 2) (Carboxypeptidase N regulatory subunit) (Q9DBB9)
Organism: Mus musculus (Mouse)
Function: The 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation. Under some circumstances it may be an allosteric modifier of the catalytic subunit (By similarity).
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Carboxypeptidase N catalytic chain
Sequence:
MFPGAWLCWVSLLLLARLTQPCPVGCDCFGREVFCSDEQLADIPPDIPPHITDIVFVETAFTTVRTRAFSGSPNLTKVVFLNTQVRHLEPDAFGGLPRLQDLEITGSPVSNLSAHIFSNLSSLEKLTLDFDRLAGLPEDLFCHMDILESLQLQGNQLRTLPGRLFQSLRDLRTLNLAQNLLTQLPKGAFQSLTGLQMLKLSNNMLARLPEGALGSLSSLQELFLDGNAITELSPHLFSQLFSLEMLWLQHNAICHLPVSLFSSLHNLTFLSLKDNALRTLPEGLFAHNQGLLHLSLSYNQLETIPEGAFTNLSRLVSLTLSHNAITDLPEHVFRNLEQLVKLSLDSNNLTALHPALFHNLSRLQLLNLSRNQLTTLPGGIFDTNYDLFNLALLGNPWQCDCHLSYLTSWLRLYNNQISNTHTFCAGPAYLKGQLVPNLKQEQLICPVNPGHLSFRALGLDEGEPAGSWDLTVEGRAAHSQCAYSNPEGTVLLACEESRCRWLNIQLSSRDGSDSAAMVYNSSQEWGLRSSCGLLRVTVSIEAPAAGP
Protein: Retinol-binding protein 4 (Plasma retinol-binding protein) (PRBP) (RBP) (P04916)
Organism: Rattus norvegicus (Rat)
Function: Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane (By similarity).
Subcellular location: Secreted {ECO:0000269|PubMed:4708098}.
Interaction partners:
- Transthyretin
- Receptor for retinol uptake STRA6
- 30 kDa adipocyte complement-related protein
Sequence:
MEWVWALVLLAALGGGSAERDCRVSSFRVKENFDKARFSGLWYAIAKKDPEGLFLQDNIIAEFSVDEKGHMSATAKGRVRLLSNWEVCADMVGTFTDTEDPAKFKMKYWGVASFLQRGNDDHWIIDTDYDTFALQYSCRLQNLDGTCADSYSFVFSRDPNGLTPETRRLVRQRQEELCLERQYRWIEHNGYCQSRPSRNSL
Protein: Uncharacterized protein (O53630)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Uncharacterized protein
- Probable conserved transmembrane protein
Sequence:
MVPVETLHSGDPITDVNGGGQRYIVLESKTVGDSCVVLELESRVNHQLQVIEKSFPAGYHVGRAHHRIL
Protein: Probable LRR receptor-like serine/threonine-protein kinase At1g63430 (EC 2.7.11.1) (C0LGH8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
- Probable galacturonosyltransferase 10
- Putative disease resistance protein At1g50180
- Cyclic nucleotide-gated ion channel 11
Sequence:
MRSKYFCSLALVLGLFFVSCDGFASNEVQALRRFKEAIYEDPLLVMSNWNDPNSDPCDWTGIYCSPSKDHVIKINISASSIKGFLAPELGQITYLQELILHGNILIGTIPKEIGNLKNLKILDLGNNHLMGPIPAEIGSLSGIMIINLQSNGLTGKLPAELGNLKYLRELHIDRNRLQGSLLVAGASGYQSKVYSSNSSANIAGLCKSLKVADFSYNFFVGNIPKCLENLPRTSFQGNCMQNKDLKHRSSSQCANAQLVKTHGSPSAAPKHQSAQMVAKHHRASKPKWLLALEIVTGSMVGLLLLVALFSAVHRWNNRSTLIIPWKKSSSEKEKFTVYVDSEMLKDVSRLTRQELEVACEDFSNIIGLSADSQIYKGTLKGGSEIAVISLCVKEEDWTGYLELYFQREVADLARLNHENTAKLLGYCKEISPFTRMLVFEYASNGTLYEHLHYGEAALVSWARRMKIVIGIARGLKYLHMELDPPFTISELSSNAIYLTEDFTPKLVDFECWKTILARSEKNLRNISSQGSICVLPNGMESRYLDVSGNIYAFGILLLEIVSGRPPYCKDKGFLIEWAKEFLEAPEAMSGLVDPELKHFNQEDLETVCEVASQCLNRDPTNNNNNHNKPSVQELCETLESRISLSISAELRSSSLAWAELALDS
Protein: Dynein regulatory complex subunit 4 (Growth arrest-specific protein 11) (GAS-11) (Growth arrest-specific protein 8) (GAS-8) (Q60779)
Organism: Mus musculus (Mouse)
Function: Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays an important role in the assembly of the N-DRC linker (By similarity). Plays dual roles at both the primary (or non-motile) cilia to regulate hedgehog signaling and in motile cilia to coordinate cilia movement. Required for proper motile cilia functioning. Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity in a GRK2-dependent manner. May play a role in the spermatozoa motility.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11751847, ECO:0000269|PubMed:21659505}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:17366626}. Cell projection, cilium, flagellum {ECO:0000269|PubMed:11751847, ECO:0000269|PubMed:31961863}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:11751847, ECO:0000269|PubMed:26387594, ECO:0000269|PubMed:27472056}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:16643277, ECO:0000269|PubMed:21659505}. Golgi apparatus {ECO:0000269|PubMed:18396146}. Cell projection, cilium {ECO:0000269|PubMed:27472056}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q7XJ96}. Note=Associates with microtubules (PubMed:17366626). Localized to the cytoplasm of round spermatids, the tails of elongating spermatids, and mature spermatid tail bundles protruding into the lumen, and in the flagellum of epididymal spermatozoa (PubMed:11751847). {ECO:0000269|PubMed:11751847, ECO:0000269|PubMed:17366626}.
Interaction partners:
- Dynein regulatory complex subunit 2
- Axonemal dynein light intermediate polypeptide 1
- Dynein regulatory complex protein 1
- Dynein axonemal intermediate chain 2
- Dynein regulatory complex subunit 5
- Dynein regulatory complex subunit 3
- Dynein regulatory complex subunit 7
- Protein smoothened
- Radial spoke head protein 4 homolog A
- Coiled-coil domain-containing protein 39
Sequence:
MAPKKKGKKGKAKGTAIVDGVAPEDMTKEQVEEHVARIREELDREREERNYFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAEERHQVEIKVYKQKVKHLLYEHQNNLAEVKAEGTVVMKLAQKEHRTQEGALRKDMRVLKVELKEQELANEVVIKNLCLKQAEEITKMRNDFERQVREIEAKYDKKMKMLRDELDLRRKTEIHEVEERKNGQISTLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEEHMEREMAEVTLQNRRLADPLQKAKDEMNEMQKRLGNHERDKQILVCTKARLKVAERELKDLKWEHEVLEQRFIKVQQEREELYRKFADAIQEVQQKTGFKNLLLERKLQALNAAVEKREVQFNEVLAASNLDPTALTLVSRKLEDVLESKNTTIKDLQYELARVCKAHNDLLRTYEAKLLAFGIPLDNVGFKPLETAVIGQTLGQGPAGLVGAPT
Protein: Sugar transport protein 2 (Hexose transporter 2) (Q9LNV3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mediates an active uptake of hexoses, probably by sugar/hydrogen symport. Can transport glucose, 3-O-methylglucose, xylose, mannose, fructose and galactose.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- At1g27000/T7N9_6)
- F3F20.10 protein
- MOB kinase activator-like 1A
- GDP-mannose transporter GONST1
- GDP-mannose transporter GONST2
- Ras-related protein RABA1i
- AT1G67850 protein
Sequence:
MAVGSMNVEEGTKAFPAKLTGQVFLCCVIAAVGGLMFGYDIGISGGVTSMDTFLLDFFPHVYEKKHRVHENNYCKFDDQLLQLFTSSLYLAGIFASFISSYVSRAFGRKPTIMLASIFFLVGAILNLSAQELGMLIGGRILLGFGIGFGNQTVPLFISEIAPARYRGGLNVMFQFLITIGILAASYVNYLTSTLKNGWRYSLGGAAVPALILLIGSFFIHETPASLIERGKDEKGKQVLRKIRGIEDIELEFNEIKYATEVATKVKSPFKELFTKSENRPPLVCGTLLQFFQQFTGINVVMFYAPVLFQTMGSGDNASLISTVVTNGVNAIATVISLLVVDFAGRRCLLMEGALQMTATQMTIGGILLAHLKLVGPITGHAVPLIVLILICVYVSGFAWSWGPLGWLVPSEIYPLEVRNAGYFCAVAMNMVCTFIIGQFFLSALCRFRSLLFFFFGIMNIIMGLFVVFFLPETKGVPIEEMAEKRWKTHPRWKKYFKD
Protein: Transcriptional repressor RHIT (Repressor of heat-inducible transcription) (RhitH) (Zinc finger protein 205) (Zinc finger protein 210) (O95201)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Olfactory receptor 1F1
- Pyrin
Sequence:
MSADGGGIQDTQDKETPPEVPDRGHPHQEMPSKLGEAVPSGDTQESLHIKMEPEEPHSEGASQEDGAQGAWGWAPLSHGSKEKALFLPGGALPSPRIPVLSREGRTRDRQMAAALLTAWSQMPVTFEDVALYLSREEWGRLDHTQQNFYRDVLQKKNGLSLGFPFSRPFWAPQAHGKGEASGSSRQAGDEKEWRGACTGAVEVGQRVQTSSVAALGNVKPFRTRAGRVQWGVPQCAQEAACGRSSGPAKDSGQPAEPDRTPDAAPPDPSPTEPQEYRVPEKPNEEEKGAPESGEEGLAPDSEVGRKSYRCEQCGKGFSWHSHLVTHRRTHTGEKPYACTDCGKRFGRSSHLIQHQIIHTGEKPYTCPACRKSFSHHSTLIQHQRIHTGEKPYVCDRCAKRFTRRSDLVTHQGTHTGAKPHKCPICAKCFTQSSALVTHQRTHTGVKPYPCPECGKCFSQRSNLIAHNRTHTGEKPYHCLDCGKSFSHSSHLTAHQRTHRGVRPYACPLCGKSFSRRSNLHRHEKIHTTGPKALAMLMLGAAAAGALATPPPAPT
Protein: UDP-galactose/UDP-N-acetylglucosamine transporter srf-3 (Surface antigenicity abnormal 3) (Q93890)
Organism: Caenorhabditis elegans
Function: Acts as a transporter of both UDP-galactose and UDP-N-acetylglucosamine into the Golgi lumen. Apparently transports UDP-galactose and UDP-N-acetylglucosamine simultaneously, and independently, by an unknown mechanism. Functions redundantly with nucleotide sugar transporter nstp-4. May be involved in gonadal development.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:15123614}; Multi-pass membrane protein {ECO:0000269|PubMed:15123614}.
Interaction partners:
- JC8.12-like protein
- N-acetylgalactosaminide beta-1,3-galactosyltransferase
- Hexosyltransferase
- Hexosyltransferase
- UDP-sugar transporter sqv-7
- Glycosyltransferase family 92 protein
- Alpha-1,3/1,6-mannosyltransferase ALG2
- Acyltransferase
Sequence:
MMGRNDDAFHPLLHSTPESSVKIPVPLVSVGRESSQSKGNMKTAILIWLTLQNSIHTLLIRYSRAREVDAMFVSTVAVWLTEVIKCFICLFLVAQEETPRRFIHALRTQILEQPYDTLKVCIPAMIYIVQNNLFYVAASHLDAATFMITSQLKIFTAAIFTVIILRRSLNRTQWFALAVLFVGVSLVQLQGTKAKESSGESPFVGFVAVVVACCLSGFAGIYFEKILKGSAPVSLWMRNVQMAVFSIPASFSAIYMQDSKTVNEYGLLYGFDSIVWLTVLWYGVGGLSVAVCIKYADNIAKNFATSVAIILSTIGSIFLFDFIPSFTFLLGASLVIFSIFLYSSHQSMVAALGRLRGEIPSTKEAFCL
Protein: DNA-binding transcriptional repressor ScoC (HTH-type transcriptional regulator Hpr) (Protease production regulatory protein Hpr) (P11065)
Organism: Bacillus subtilis (strain 168)
Function: Negative regulator of protease production and sporulation. Acts by binding directly to the promoter of protease genes (aprE and nprE), and by repressing oligopeptide permease operons (appABCDF and oppABCDF), thereby preventing uptake of oligopeptides required for initiation of sporulation. Acts with SinR as a corepressor of epr expression. Binds to non-m6A-5-methylated 5'-GACGAG-3' sites, tested with scpA; when the target is methylated by DnmA, this repressor no longer binds and transcription is up-regulated.
Interaction partners:
- Catabolite control protein A
- HPr kinase/phosphorylase
- HPr-like protein Crh
- Phosphocarrier protein HPr
- Transcription antiterminator LicT
- Mannitol-specific phosphotransferase enzyme IIA component
- Transition state regulatory protein AbrB
- Global transcriptional regulator CodY
- Phosphoenolpyruvate-protein phosphotransferase
- HTH-type transcriptional regulator SinR
Sequence:
MNRVEPPYDVKEALVFTQKMAQLSKALWKSIEKDWQQWLKPYDLNINEHHILWIAYQLNGASISEIAKFGVMHVSTAFNFSKKLEERGYLRFSKRLNDKRNTYVQLTEEGTEVFWSLLEEFDPTRNAVFKGSQPLYHLFGKFPEVAEMMCMIRHIYGDDFMEIFETSLTNIDNDFESVNGKLKKKAKDSAADEPAEELEPVNS
Protein: E3 ubiquitin-protein ligase RDUF2 (EC 2.3.2.27) (RING and DUF1117 domain-containing protein 2) (AtRDUF2) (RING-type E3 ubiquitin transferase RDUF2) (Q940T5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: E3 ubiquitin-protein ligase involved in the positive regulation of abscisic acid-dependent drought stress responses. Possesses E3 ubiquitin ligase activity in vitro.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9SNB6}.
Interaction partners:
- NEP1-interacting protein-like 1
- Elongation factor G, putative
- AT3g59080/F17J16_130
- Eukaryotic aspartyl protease family protein
- Aspartic proteinase Asp1
- Aspartic proteinase Asp1
- At3g50050
- Eukaryotic aspartyl protease family protein
- Eukaryotic aspartyl protease family protein
- Eukaryotic aspartyl protease family protein
Sequence:
MPSTPTTPTTTTPITASYWCYSCTRFVSVWADQGTTTVGSVACPHCDGGFIEQINDSSSAATELTIPASTEVRSINNNRRSVIRRRRSGRRPSFNPVIVLQGGAGEREEGEEGDAARDRRAFEFYYDDGSGSGLRPLPDSVSEILMGSGFERLLEQLSQIEASATGIGRSGNPPASKSAIESLPRVEISDCHIGSEANCAVCTEIFETETEAREMPCKHLFHDDCIVPWLSIRNSCPVCRFELPSEPNRRSNNNEEDNAVGMTIWRLPGGGFAVGRFNAAMRDGERVLPVVLTEMDGGGIGNSQDGPRRISWVRSHGTLESDSNGTGSGSGSGGRLRRMVRGMVSLMRRVRPNRSSSSSSAAISTSSDNLDLNIEVESRVLDRSNSVMRRYFRRNRSNRDSSSSVLH
Protein: CIN85 and CD2AP related, isoform E (A0A0B4KI32)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPGGWWQGTLKASGVTGMFPDNFVRVLESGVSSNGNGTTGSGDHIEVGTAVQLRDKSATSNRRCKVIYSYTQVNDDELTLAVGDVIEFLGEVEEGWWRGRLRSKVGVFPSNFVQHIEPSPVLASKRPPTIGATVTTSALTSKAANVANVAATATVPTGGAVPPASTSISTSTTKQATKSRATAAAAASAPAEPAAIVSGSGAAAGGGAAAAVPMLPPKPQREFCRVEFPYAPQNDDELELKVDDIIAVISTELPDKGWWKGEIRGKVGVFPDNFVKMLAPSEVAPINEPPSATQITQNQRKVSNTASTTSHMTTTNSSNSSTTSVTTQQQKEQIGGSSSTTSKVYIKKTGSSSNSTTSSTTTASSSAGRKESFGSRDSLNDILSETGLPTGNVAAQRKSLENKNLDLTKPPGVGASVSIGQQRSSTSSATTSSATTVATGLTSSSVSKSMENMLDEKVKSPPPPVLSKKPSVPLKKTPTGGVPMTGNLLGGKKKNTEGKLTTAVSHDLADGLAASKMLSGANQLPESGAAGNVVIRRAATIAVEDTDFDRVERASILTDMRQGRVKAPKRRPPSAAINVLGESNNNSVYVNGSGMSGSGGAGSASELSEDGGAGGKTSDDNSTGEEPQLAKPKPREWEKKKAPWMEELKASQVTRKKTSPSVEPRGASVAERTSKLFAAEQAVSSNSSSITTKVQSSAVTSSMFVENSTTSSSVITSSSHTTTNDAIMSRSLSAAKVQTASSDEETRATRPNSLAIRNQRSVSPLVKSSNASSSQSQEEKPTSQLNNHQDASSSRVAQLEQRVDKLEGLVLNQQRTIEELVNALKSEAERVKILRSELDKYAQCVTQV
Protein: Pre-mRNA-splicing factor PRP11 (Q07350)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: mRNA splicing factors, PRP9, PRP11, and PRP21, are necessary for addition of the U2 snRNP to the pre-mRNA in an early step of spliceosome assembly.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Protein HSH49
- U2 small nuclear ribonucleoprotein A'
- Small nuclear ribonucleoprotein Sm D3
- Cold sensitive U2 snRNA suppressor 1
- Pre-mRNA-processing ATP-dependent RNA helicase PRP5
- Pre-mRNA-processing factor 19
- RDS3 complex subunit 10
- Pre-mRNA-splicing factor PRP9
- Pre-mRNA-splicing helicase BRR2
- U2 small nuclear ribonucleoprotein B''
Sequence:
MNYLEGVGSKKGGGGIASESQFNLQRRKEVESLLSKGENVPYTFQDEKDDQVRSNPYIYKNHSGKLVCKLCNTMHMSWSSVERHLGGKKHGLNVLRRGISIEKSSLGREGQTTHDFRQQQKIIEAKQSLKNNGTIPVCKIATVKNPKNGSVGLAIQVNYSSEVKENSVDSDDKAKVPPLIRIVSGLELSDTKQKGKKFLVIAYEPFENIAIELPPNEILFSENNDMDNNNDGVDELNKKCTFWDAISKLYYVQFFFKQAEQEQADV
Protein: ALBINO3-like protein 2, chloroplastic (Ath5) (Q8L718)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probably required for the insertion of integral membrane proteins into the chloroplast thylakoid membranes.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Large ribosomal subunit protein mL45
- AT2G34250 protein
- F9K20.24 protein
- SecY protein transport family protein
Sequence:
MAVWRSCLRASSSRHRLSSLFFSHHLKPSSFISHSPPLFSPSPSPSPTCFSPLHRLLSSGPEFPIGSQEIIPTDDSSLPVLAVVDFLEGFHEFTGLPWWMIIASSTVAVRLALLPLLILQLKKLKTISELLPKLPMPIPETPTLKGSIDQFSHFLKESRAIGCPSFLWFFPYLSVQLPCFFLLMASIRKMSLDGHPGFDSGGVLWFQNLSDLPGGSFGPVFPILIATFHYINIQISFDTSTIRQTTGLTGLLMRYYKLYLEILSVPLFFVGYAIPQGSLVYWVTNSSVNIFQQLSLKHPTVGAKLGLLSQGATPGMGHSMEISESVIKYVDSDSKEQTLSLQTLTPEELLSLSVQVLSKGDKETSIQLLRLALEKDPGYVRGLVLMGQALLQKTQLSEATEYLELAISKLLDEDPSDAEDVELLMLASQWAGAAYVQQGKLKSGIIHLERVAKLREPGDPKSKEHYFEALLLLSSALYKEGQSDEAAKILRVVVDHNPAYKPLLEQCEDENELVSDLVSRRKDHF
Protein: Biliverdin reductase B (A0A8I6AHQ8)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MAVKKIAIFGATGRTGLTTLAQAVQAGYEVTVLVRDSSRLPSEGPQPAHVVVGDVLQAGDVDKTVAGQDAVIVLLGTGNDLSTEPPLCPRPLPAPRPPAPPPPPAPPLPPLPPPPPPPASDSHSLSPLRSYYSNVRGHPEHCGSHEGTWSGQAFLLWDPSKVPPRLQDVTDDHIRMHKILEESGLKYVAVMPPHIGDQPLTGAYTVTLDGRGPSRVISKHDLGHFMLRCLTTHEYDGQKTYPSHQYD
Protein: Nuclear receptor ROR-alpha A (Retinoid-related orphan receptor alpha 2) (Retinoid-related orphan receptor-alpha A) (F1QLY4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) (By similarity). Required for proper cerebellum development.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P35398, ECO:0000255|PROSITE-ProRule:PRU00407}.
Interaction partners:
Sequence:
MMYFVISAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNAAYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRLQQQQRDHQQQPGEAEPLTPTYGLSTNGLTELHDDLSGYMNGHTPDGTKPDSGVSSFYLDIQPSPDQSGLDINGIKPEPICDFTPGSGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHMETCQYLREELQQMTWQAFLQEEVENYQSKPREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFVRMCRAFDPQNNTVYFDGKYAGPDVFKSLGCDDLISSVFEFGKNLCSMHLSEDEIALFSAFVLMSADRSWLQEKVKVEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCSRHTEKLTAFKAIYPDIVRAHFPPLYKELFGSDFEQSMPVDG
Protein: G protein-coupled receptor EGL-6 isoform b (G-protein coupled receptors family 1 profile domain-containing protein) (G5EFX1)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
- FMRF-Like Peptide
- FMRF-Like Peptide
- Inward rectifier potassium channel irk-1
- Probable G-protein coupled receptor egl-47
- Neuropeptide receptor 3
- G-protein coupled receptors family 1 profile domain-containing protein
- G-protein coupled receptors family 1 profile domain-containing protein
- FMRFamide-like neuropeptides 1
Sequence:
MGKWTELGLSGRENATNVSSRAITDKSFLQYYDEIHIPLSISICIFGAASNVFNIIVLTRKRMRTPINILLTGLSIAQWLLATNYFLYLLLEYYRYQCVQLLWSEAFTRYRFFNVNLNTVFHTIAFTTTIVVAVFRYCALKFPIQANRFIYKCQPAIAANVIIWIIIPIISLPLFFISEVKIVARDHVAYDLQCEMEGPLYDLSYQESPLLVSAVFWAFGIVFKLLPSLILSILLIALIRSLKSVERRRKNWKRTQGANICTNSERKAKRKLTTRPRTTRMLVIILLLCVMVELPMGILNLCVAIYGEEFGNRYYDPVGNLMEMLTLLYSSVSFVLYCTMSNEYLSTFRALFFPWTRKNSLRGTRRSWNHRHDDETKSPRTFLINRTAPSSYVGS