wanglab/gogpt-training-data huggingface dataset:
Protein: MEFV innate immunity regulator, pyrin (F8W6Z2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARPVKMATLLVTYYGEEYAVQLTLQVLRAINQRLLAEELHRAAIQDMGSCYVAQVGLELLISNNPPIFASETAGITGRPPDTAASPRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASGSRSPGCPRCQDSHERKSPGSLSPQPLPQCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKTVPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQGPD
Protein: VWFA domain-containing protein (Q57X62)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- poly
- Flap endonuclease 1
- KU80 protein
- DNA-repair protein, putative
Sequence:
MNCEHVAYTTCASNGCGVLTANTFTPLTLVACSVEVEVHGNSARLNVRYEYNNYTGKDQRVIAAYPLPMWWDLMSCRADYAKDSVVGVHCVTIPLNVEVSDAAATSFPILPGPKPDGVVAIVAAQRLPWMIGLGSSVLIGATYAVPLNALCKAGEFRMVLPMELFPDAPPPPPSTMEYESLFAMKWPSKLPKGLTIDVKCKTFTPLAGTVELRPTGGNVCDPVPAQVEIVGDSGFRLHYEGPLAARVRGGFELFCPLFRTIEPLRFFVEVDNGREVCDDDRYALTLVLTPVVAEQLSATVNAELIFVVDSHSNYASACMSQALRVALYGAPDKAPVNIILITEENDICLCPGGSTQVNQLDIDGLAAFVAQTRPQRPSVGVSHLNRVMRSLVNSESTGPCGPVPRGFVRHIIVLSDEGTKSHAVEAISLAAHHQHNMRFSAVGLITAGGANAAALQLLAQEGGGVYYDATDAEELQAVLAQVVSLVAVPTVTDVELRFREPEVRVESKQLRAIPQGLQQFVQCFVPASLENFHVVVIGRIGSASVEYTGQGSLTEVFLTACSEPQNAFSVGMLHLSAAASRIRYLVEGRSSFTLNKSEVQEVGRYSETYMLPSPFTEMKQIRPSVGGGARSQTIPGAADTPIVAAARYVPRHWLYAQFLQRLSCRRLAEGLIDCRPQQLRQKIRQLEGATTNGDAPIVQQHSSASTLGKPRTTKEFIRHILMDIVDSVLATSLCVRRIAALQAPDGSFSLDSRLAVCVGLPCDRMKLDSLIVEDNAGEEHCEAQDVCKDKERLWATSLVVVSIEKQPSGIVTLAYRKAMSFIENNDPKGGFINRAREVFAGV
Protein: Catechol O-methyltransferase domain-containing protein 1 (EC 2.1.1.-) (Q86VU5)
Organism: Homo sapiens (Human)
Function: Putative O-methyltransferase.
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MTQPVPRLSVPAALALGSAALGAAFATGLFLGRRCPPWRGRREQCLLPPEDSRLWQYLLSRSMREHPALRSLRLLTLEQPQGDSMMTCEQAQLLANLARLIQAKKALDLGTFTGYSALALALALPADGRVVTCEVDAQPPELGRPLWRQAEAEHKIDLRLKPALETLDELLAAGEAGTFDVAVVDADKENCSAYYERCLQLLRPGGILAVLRVLWRGKVLQPPKGDVAAECVRNLNERIRRDVRVYISLLPLGDGLTLAFKI
Protein: SOS Ras/Rac guanine nucleotide exchange factor 1 (A0A8I6B4D6)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MWRFVFKGQCSTHLIVHTSWEFVKGFTIATSTGSEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPAERIHHLLREVLGYKIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDVEDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSSYDVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYARDVLRPGFHERFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQLEEKSEDQEDKECMKQAITALLNVQSGMEKICSKNLAKRRLSESACRFYSQQMKGKQLAIKKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRLPGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDGNSVIFSAKSAEEKNNWMAALISLQYRSTLERMLDVTMLQEEKEEHMRLPSADVYRFAEPDSEENILFEENVQPKAGIPIIKAGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLNLLIERFEIPEPEPTEADRIAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDVDLLQRMEEFIGTVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQNSPPTVEWHISRPGHIETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLRRHGKELINFSKRRRVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRNPKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAPNSPRTPLTPPPASSASSNTDVCSVFDSDHSASPFHSRSASVSSISLSKGTEEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQLIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS
Protein: Adenosine kinase (AK) (EC 2.7.1.20) (Adenosine 5'-phosphotransferase) (A0A5F9ZH31)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU368116}.
Interaction partners:
Sequence:
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKAAEAHVDAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKARVCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGNETEAATFAREQGFEKVKSLLLLSWIKTRKKLLIPMELEMHLLEVFCLNWSLTSL
Protein: Conserved hypthetical protein (Q8GGP1)
Organism: Streptomyces atroolivaceus
Interaction partners:
Sequence:
MTITSSLDVRPEIKQAVTVRPGMCGPGSLFVGQLGDWTWETVSAQCDTDVFAARDASGNPTYLAFYYFRVRGGRELHPGSLTFGDRLTVTSGCYDQGTESVLTLHRIDRAGSDDAQRPLDLHEFYERPRDGSLYVENFNRWVTRSAPGSNEDLVKSSPPGFRNDGLPQLPAAYSPRAVYREARTAHTFRALDEPGFRLLPDTVEVEHPVDIVRDVNGVGLLYFASYFSMVDKAALALWRRLGRSDRAFLRRVVVDQQMCYLGNADLDSVLTLGARVRVSTETPGEELVDVVISDRDSGRVIAVSTLHTQHDAHDPKGEA
Protein: Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (Q18445)
Organism: Caenorhabditis elegans
Interaction partners:
- Uncharacterized protein T27F2.1
- Pre-mRNA-splicing factor syf-2
- Cell division cycle 5-like protein
- Tr-type G domain-containing protein
- Pre-mRNA-processing factor 17
- Pre-mRNA-splicing factor 8 homolog
- Probable ATP-dependent RNA helicase DHX35 homolog
- Pre-mRNA-processing factor 19
- Peptidyl-prolyl cis-trans isomerase 10
- Intron-binding protein aquarius
Sequence:
MPAPINDQAPYVILDTTMGKIALELYWNHAPRTCQNFSQLAKRNYYNGTIFHRIIADFMIQGGDPTGTGRGGASIYGDKFSDEIDERLKHTGAGILSMANAGPNTNGSQFFITLAPTQHLDGKHTIFGRVAAGMKVIANMGRVDTDNHDRPKIEIRILKAYPSESSVLS
Protein: Phosphotransferase (EC 2.7.1.-) (Q6FXT8)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- ATP-dependent 6-phosphofructokinase
- ATP-dependent 6-phosphofructokinase
- Glucose-6-phosphate isomerase
- phosphoglucomutase
- phosphoglucomutase
- phosphopentomutase
- Phosphomannomutase
- 6-phosphofructokinase
- Mannose-6-phosphate isomerase
- Glucosamine 6-phosphate N-acetyltransferase
Sequence:
MVHLGPKKPPTRKGSMVDMPQQLLDQIKVFEEMYTVDGETLRKVTKHFITELDKGLSKKGGNIPMIPGWVMEYPSGKEKGDYLAIDLGGTNLRVVLVKLGGDRTFDTTQSKYKLPEAMRTTKNHEELWSFIADSLQAFLEDQFPEGVKGKLPLGFTFSYPASQDRINQGVLQRWTKGFDIPNVEGHDVVPMLQKQIEKRNLPIDIVALINDTTGTLVASLYTDGETKMGVIFGTGVNGAYYDVVSDIPKLEGKLADDIPNDSPMAINCEYGSFDNEHVVLPRNKYDLIIDEESPRPGQQAFEKMSSGYYLGEMLRLALLDLYDQGLILKGQDISKLKKPYVMDTSYPSKIEDDPFENLEDTDELLQKNLGIQTTVQERKLIRRLCELIGTRSARLSVCGIAAICQKRGYETAHIAADGSVFKMYPGFKEKAAQGLADIYGWEHKDPKDCPIVIVDAEDGSGAGAAIIAALAEKRIAEGKSLGVLGA
Protein: Threonylcarbamoyladenosine tRNA methylthiotransferase (EC 2.8.4.5) (tRNA-t(6)A37 methylthiotransferase) (Q584Z1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Exosome complex exonuclease RRP40
Sequence:
MKRNSAREGDIEDFFCNSSLSAPRGNCAQNVNSRRRRVVREDYGPGIPGNATIFVHTFGCGHNVSDGEYMAGQLVESGYNVTDEFGQADAYLLNSCTVKNPSEEHFVSMMNRVRDTGKPLIVAGCVPQADPTNKQWGDVSVVGVRSIDCVSYVVQEALQGNCVRLLGETEDQRQSNESNELPALDLPKVRRNKYIEIIPISVGCLNNCTYCKTKQARGDLRSYPVEVIVDRVREVVRDGVKEIRLTSEDSGAYGIDIGTDVVYLLRAVAVELEGTDVMLRVGMSNPPYLLRHVDGFATVLKHPNVYEFVHIPVQSGSDSILQTMLREYTVEEFFMCIDSIRAAVPKATVATDIICAFPGEGESEWQETMELCKRAKFEVINITRFYPRRNTPAAAMKQIPTDVAKHRTTELTNFFNSYRTFDSMVGEVHNVTLLETAHDKHHLVGHTKNYVQVLVDPAQARMGESVVVVITSATKYSVMGRVLRSRWERLSADAVGFATAPFRTRKGRIASALLMATAVGTVLLYWSSTRRRRCK
Protein: ATPase Get3 (EC 3.6.4.-) (Arsenical pump-driving ATPase) (Arsenite-stimulated ATPase) (Guided entry of tail-anchored proteins factor 3, ATPase) (G3V9T7)
Organism: Rattus norvegicus (Rat)
Function: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors GET1/WRB and CAMLG/GET2, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the GET1-CAMLG receptor, and returning it to the cytosol to initiate a new round of targeting.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:O43681, ECO:0000255|HAMAP-Rule:MF_03112}. Endoplasmic reticulum {ECO:0000250|UniProtKB:O43681, ECO:0000255|HAMAP-Rule:MF_03112}. Nucleus, nucleolus {ECO:0000250|UniProtKB:O43681, ECO:0000255|HAMAP-Rule:MF_03112}.
Interaction partners:
- Guided entry of tail-anchored proteins factor 1
- Guided entry of tail-anchored proteins factor 4
- Guided entry of tail-anchored proteins factor CAMLG
- Low molecular weight phosphotyrosine protein phosphatase
- Syntaxin-5
- Small glutamine-rich tetratricopeptide repeat-containing protein alpha
- OCA2 melanosomal transmembrane protein
- RAD23 homolog A, nucleotide excision repair protein.
- Peroxisomal ATPase PEX6
- UV excision repair protein RAD23 homolog B
Sequence:
MAAGVAGWGVEAEEFEDAPDVEPLEPTLSNIIEQRSLKWIFVGGKGGVGKTTCSCSLAVQLSKGRESVLIISTDPAHNISDAFDQKFSKVPTKVKGYDNLFAMEIDPSLGVAELPDEFFEEDNMLSMGKKMMQEAMSAFPGIDEAMSYAEVMRLVKGMNFSVVVFDTAPTGHTLRLLNFPTIVERGLGRLMQIKNQISPFISQMCNMLGLGDMNADQLASKLEETLPVIRSVSEQFKDPEQTTFICVCIAEFLSLYETERLIQELAKCKIDTHNIIVNQLVFPDPEKPCKMCEARHKIQAKYLDQMEDLYEDFHIVKLPLLPHEVRGADKVNTFSALLLEPYKPPSTQ
Protein: Putative metacaspase (E9AEY0)
Organism: Leishmania major
Interaction partners:
Sequence:
MADLFDIWGIGAVASLIPMLANGLLLVDRPKRVDINAGRRLIHTVRPIIPYRAPVPYTGGRVRALFIGINYTGMRNALRGCVNDVSSMLGTLQQISFPISECCILVDDPSFPGFCGMPTRDNIIKHMLWLTGDVRPGDVLFFHFSGHGGQAKATRDSEEKYDQCLIPLDHVKNGSILDDDLFLMLVAPLPSGVRMTCVFDCCHSASMLDLPFSYVAPRVGGGGACEYMQQVRRGNFSNGDVVMFSGCTDRGTSADVQNGGHANGAATLAFTWSLLNTHGLSYLNILLKTREELRKKGRVQVPQLTSSKPIDLYKPFSLFGMITVNASMMHCVPQQYQQRPQSLPPQVMPPATGYPVHVPPPPQGYYPPPQSPGWGLGYPVQGIPVQQATLGVSRCPPSQYLPAPPPAVYAPPPPGQRGPPQPPPAQYTFSPLPPG
Protein: Expp1 protein (Q94AI8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- 2-
- 2-
- Ribosomal protein S5/Elongation factor G/III/V family protein
- Elongation factor 2
Sequence:
MARFFLLCCLFAAVLTSSLTEAGDNNQVYSPCSDSTVAIGDGFTFGIAFAAKDSFFSTNRSKSVQYSPCDHRHLSLNGNSEVAVFRPKVDEITLLTINTSSSSSFRPDASKGYMVAFAGAKYAARSLPIMVADSNHIVTSFTLVLEFQKGRLENMFWKKDGCSKCSGDSKFVCLNKEECAIKPQNCKNQGGQVDCSLGIQLAFSGTDKHYTALNSWYEVANLKQYSLYGLYSNLKDSLTNPFKNIF
Protein: DNA damage-binding protein 1 (UV-damaged DNA-binding protein 1) (OsUV-DDB1) (Q6L4S0)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Required for DNA repair. Binds to DDB2 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex). The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair (Probable). May function as the substrate recognition module for a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Os04g0691200 protein
- Os01g0580300 protein
- Os03g0786800 protein
- Os03g0699100 protein
- Expressed protein
- COP9 signalosome complex subunit 5
- Os03g0187300 protein
- Os02g0307200 protein
- Os01g0857900 protein
- COP9 signalosome complex subunit 1, putative, expressed
Sequence:
MSVWNYVVTAHKPTSVTHSCVGNFTGPNQLNLIVAKCTRIEIHLLTPQGLQPMIDVPIYGRIATLELFRPHNETQDFLFIATERYKFCVLQWDGEKSELLTRAMGDVSDRIGRPTDNGQIGIIDPDCRLIGLHLYDGLFKVIPFDNKGQLKEAFNIRLEELQVLDIKFLYGCVKPTIVVLYQDNKDARHVKTYEVALKDKDFVEGPWSQNNLDNGAGLLIPVPAPLGGVIIIGEETIVYCNANSTFRAIPIKQSIIRAYGRVDPDGSRYLLGDNAGILHLLVLTHERERVTGLKIEYLGETSIASSISYLDNGVVYVGSRFGDSQLVKLNLQADPNGSYVEVLERYVNLGPIVDFCVVDLDRQGQGQVVTCSGAFKDGSLRVVRNGIGINEQASVELQGIKGLWSLKSSFNDPYDMYLVVSFISETRFLAMNMEDELEETEIEGFDAQTQTLFCQNAINDLLIQVTANSVRLVSCTSRELVDQWNAPEGFSVNVASANASQVLLATGGGHLVYLEIKDSKLVEVKHIQLEHEISCVDLNPIGENPQYSSLAAVGMWTDISVRILSLPDLELIRKENLGGEIVPRSVLLCTLEGVSYLLCALGDGHLFSFLLNASTGELTDRKKVSLGTQPISLRTFSSKGTTHVFASSDRPTVIYSSNKKLLYSNVNLKEVNHMCPFNTAAIPDSLAIAKEGELSIGTIDDIQKLHIRTIPLNEQARRICHQEQSRTLAFCSFKHNQTSIEESETHFVRLLDHQTFEFLSIYQLDQYEHGCSIISCSFSDDNNVYYCVGTAYVLPEENEPSKGRILVFAVEDGRLQLIVEKETKGAVYSLNAFNGKLLAAINQKIQLYKWMLREDGSHELQSECGHHGHILALYTQTRGDFIVVGDLMKSISLLVYKHEESAIEELARDYNANWMSAVEMLDDEIYIGAENNYNIFTVRKNSDAATDEERGRLEVVGEYHLGEFVNRLRHGSLVMRLPDSEMGQIPTVIFGTINGVIGIIASLPHEQYVFLEKLQSTLVKFIKGVGNLSHEQWRSFHNDKKTSEARNFLDGDLIESFLDLSRNKMEEVAKGMGVPVEELSKRVEELTRLH
Protein: Quaternary amine transport ATP-binding protein (EC 7.6.2.9) (F9UNY1)
Organism: Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1) (Lactobacillus plantarum)
Subcellular location: Cell inner membrane {ECO:0000256|RuleBase:RU369116}; Peripheral membrane protein {ECO:0000256|RuleBase:RU369116}.
Interaction partners:
- Glycine betaine/carnitine/choline ABC transporter, substrate binding protein
- Glycine betaine/carnitine/choline ABC transporter, permease protein
- Glycine betaine/carnitine/choline ABC transporter, permease protein
- Glycine betaine/carnitine/choline ABC transporter, substrate binding and permease protein
- ABC-type quaternary amine transporter
- Multidrug ABC transporter, ATP-binding protein
- Oligopeptide ABC transporter, permease protein
- ATP synthase subunit delta
- Cyclopropane-fatty-acyl-phospholipid synthase
Sequence:
MFLTMEHLNKTYPGGKVAVEDFNLEIEKGEFVCFIGTSGSGKTTTMRMINRMLSQTSGTIKLNGKDISQIDPVKLRRQIGYVIQNIGLMPHMTIRDNITLVPRLLKWPQDKMNERAKKMIKLVELPEDYLDRYPSELSGGQQQRIGVVRALAADQDLVLMDEPFGALDPITRESLQDLVKDLQERLGKTFVFVTHDMDEALKLATRIVIMDGGDIMQVDTPDGILRHPANEFVENLIGKDRLIQARPSITTVGQVMLKDPIATTPGKSLTVALRQMHDKRVDSLLVTDEAGILKGVIGIEDVDYNFNSATSVGDIMKTDLFYVQSNSLIRDTVERILKRGLKNIPVVDEQHRLVGIVTRATLVDIVYDALWGDEDEDEAENNIHHGEDDAPAEGGEQA
Protein: Mitochondrial import inner membrane translocase subunit TIM9 (Q6FRT3)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Function: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Intermembrane side {ECO:0000250}.
Interaction partners:
- Mitochondrial import inner membrane translocase subunit
- Mitochondrial import inner membrane translocase subunit TIM22
- Mitochondrial import inner membrane translocase subunit
- Candida glabrata strain CBS138 chromosome J complete sequence
- Candida glabrata strain CBS138 chromosome L complete sequence
- Mitochondrial import inner membrane translocase subunit TIM54
- Mitochondrial import inner membrane translocase subunit TIM8
- Mitochondrial import inner membrane translocase subunit TIM13
- Succinate dehydrogenase cytochrome b small subunit
- Mitochondrial import inner membrane translocase subunit TIM23
Sequence:
MDQLNAKEQQEFQKLVEQKQMKDFMRLYSGLVERCFTDCVNDFTSSKLTSKEESCILKCSEKFLKHSERVGQRFQEQNAALGQGLGR
Protein: SWI/SNF chromatin-remodeling complex subunit sol1 (SWI/SNF complex subunit sol1) (Switch one-like protein) (Transcription regulatory protein sol1) (O74365)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00355, ECO:0000269|PubMed:16823372}.
Interaction partners:
- SWI/SNF chromatin-remodeling complex subunit snf5
- SWI/SNF and RSC complexes subunit arp9
- SWI/SNF chromatin-remodeling complex subunit snf22
- SWI/SNF global transcription activator complex subunit snf59
- SWI/SNF and RSC complexes subunit ssr3
- SWI/SNF and RSC complexes subunit ssr2
- SWI/SNF and RSC complexes subunit ssr1
- SWI/SNF chromatin-remodeling complex subunit snf30
- SWI/SNF and RSC complexes subunit arp42
- Transcription initiation factor TFIID subunit 14
Sequence:
MNNQGFVPASDYPTAVSYPTQGQSYNTQEEQPAYPQRFSTSQGMYAAEYGNANMMNTSENEPNNLAHSQPFRQSPSTQRNLPNQSFDFASNGAWNGSGSVKYSSPMMPSSRIPFQQEKEAAMQQQQQQQQQQQLYQRQMQSREALLSQQIPPNQIGINAHPAVRQTPQPAPSPNTPSGNANQLTPAYAASFDKFMVSLISFMEKRGTPIKSYPQINNTPINLMMLYALVMRAGGSRQVSAHNFWPKISASLGFPSPDAISLLIQYYNSYLLPYEEAWLAAQQQQKSLQQAKANHSANVQSRPKNYPQKPVQTTPEAVHANGSMHGSLHSKSPSPAFTANRFSPAAPTTVSSERNAPPYPSAPTRPTPPTVQTSSSAAPVDSAEPVAYQPIKKPIDPMLGYPLNVAATYRLDESLLRLQMPSIVDLGTVNIQALCMSLQSTLEKEITYAMNVLLILTNDQKWMFPLSECQDVVDALIDVATQCLDNLLSVLPNEDLMEIADKRPSYRQLLYNCCVEISQFSREDFSNSLSENKTKDSINAIDVHNSEQNLLAVFVIFRNLSHFEANQNVLVQNPDFFPLLIRVVKSLNFHATSLLRSSRNTLDLHKDVLIVLCQLSQNFILPNVDVARHVLLFILSFSPFNRKKSKTILNDTLPTSIPSYTPATHPYAGPAINAYAKLLAKDANNKTNFQAIFDNNPKFLDSLFLLLASVVPKFNRHCLKICERRLPLLQQSFFCLAATVSYVKQSEQAANWCNIGEGFFVSMLRLLILLSGHPSLNPPSRVASQYPTTNPFRYVIQSGISTVRRLLSLVEAGNISLSSFPKSETLLAVLLAPTTETSFLKEISNLLDRTGDSDASLENTDDKSGI
Protein: Post-transcriptional regulator MKT1L (Inactive endonuclease MKT1L) (Q38C92)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Involved in post-transcriptional regulation of gene expression.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:32532821}.
Interaction partners:
Sequence:
MRKAGANRNNERQGRNLGQQGPQMSPPGPSMMYPHHHQHQHHHQHQHQHQHQHQHPHQHPHQHHHHHPHHNGVYGNAYDNIRQPQMPPHSFGQGVSGSPWNSPPQQTPMYNQGYNQMSPGTGGGYGDMGGMYRDVHGGQYPSSPSHMGGGANIPYGRNPAMHNGLPAGAPLPGGYGALPHQGAHTPMGFGRGGQPLMEHMQPSGMYGAPMMRHDGYPDTRVSPPAQVGYGAGAPVGPPPPPPMPAGPPYGGVLPGAGVGPGGPMNASRPPAGIGGGGGGGGNAGYLEMRARGMGPQMPASNASRPPRIGTPDPGMMPPNRMNQSPMMGQGLPPQVGNFMPLPGVSPSPHAMIPTTPSMGDTFPGDDANMSGSTEALYDFLHDRGLVSVDNISKFFPEGYGKDDPALKVAVDGNFCLTSLRDELRKRDSLWFLHSTLPEELLMLVQQHVEWMRNMKLEPIWVFNGLSVSGDVETFLTTEAELRARDAVWSKLEDGEIPDEVEIQEAFDQPLGEDVQMAVARYLKEELGVMAVTAPFLNWAQMVAFHKEGIADLLMGPPEMLLLPYDEMKVIVQIDVSNSSVNYLDRDRVLRALFPNHVTETNTRVAGDRLMDLGLITATHAALSSARVTLNLSMQEVYEELSTPTPKFRSIKDFINAHACSQETGKKAGLSIKHSKGRGYLRYSAVFSTKSRDTPLVYLVRVLDPDLTNADMPTNLAGVLGHLVPLSLFYMQFSGLLSVRIMTAITQSYLRDECPVSDTKDYHTTLGLLMTMRSQVIGQILKRIAHPPPIKRTECLSWVRWFQPILAPMDRPRDLIDLDEWEISDSDQLKKLDEDCLADYSIASVLSVTADASRPAVEESNRPAGRVPIRYNSKRETFLAILLKSFDFLGYFSHSTAPNDAVDGMEMECCGMDGHDRGGSVPAAYHEKDLSSMKRSEASDINFMADEGLKDYPSVYFPIYLRATIKANPLDVQASFVLLTELVRVRIINSNPCRYINPANQQVEISMDDQDTNSDSRVLLASRIACLVKLPYRRASENLPFVWAPVYSRHLCAFTVMVRAMCRCLRELVEVITSTVFLSGNSSCSLQDFAEFASILPFGDVPSTIGGLLLHYVLVFPSDYQANLTSREERIEYLQGKFRDIPDLADHLHLVMSFTLQALYLINAYMLNDKETIVAKDQLTGTIVEDTIEMMWQKWRDHIDDNPPGDIHNLYPPRHQEPIPH
Protein: Uncharacterized protein C11C11.05 (Q10196)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Protein big1
- Protein rot1
Sequence:
MKTTMLMLVLLVCSYIHYVCAQIRFVTPATTDSMDFTAISFSWEESNTGIPLEDITNTVFYICSGSMDAPQPCAVLYTSPSPSSISQAGPFAISQVFGPAGRLYFLWAQSTYAGGIVNDYTDFFTVNGLTGTFDNYEIYASLMALGVYPYVPTLTGFSTFLGVWPTGTMRDWYLSQTTGVLRTGPIQNRPDSTFTAATTDIQPLWETSSYSVFTTFAGPPIATSTVFASPTYMYTLYANYASTASKPTIIATPTAGLRRRDSWAQAAPKRGMRLGEHKRGLLYS
Protein: BmRelish1 (A7BJ65)
Organism: Bombyx mori (Silk moth)
Interaction partners:
Sequence:
MSTTASDQDSDSSSRSPQSYYSYCSPSQQVPQLTPDLNNLIYLDNGSKRNRPFLRIIEQPQDYFRFRYASEMAGTHGCLLGKSSSTNKNKVHPTVELVNYTGQAVIKCQLAQHKTPEEHPHKLFEEEQDNDDREVSCIVPKQGIYKVGFGGMGIIHTAKKNVPGLLFQKYAEKCKNISNKELKIQCENMAKSIDLNIVRLKFSAHDISTDREICKPVFSEPIHSLKSAASNDLKICRISRCSGRPVGGEDVYIFVEKVNKKNIQIRFFELDENGHRVWTANGSFMPGDVHHQYAIIFRTPAYKDTKISKNVNVYIELARPSDGRTSEPKEFKYIAEPIYSNSKKRRMNASCSTSPASSGSLKSISDLPALVTLNNNFNDENNIEMPKTELPAAAAAAPSLGLCDLADALMGSESAVDLHSVAGNAMWSPSAPVETMSVEQFPNLQLNSTEFEKIITNALPPEERNDFTEYALSSYESFDDIDDDPNGWKFIRTLQMMQTDSARSRQQTPQTSKPALKTVEPQESSDRTELNVPSDAKDANEYSAYYNAQDGLEVKQLLRELTQIIRNKKVHKKQELKDKLKRLFDIRLSNGDTYLHMILCSNQSSIANMVTIIDSVKMTHLLDYRNLKLQTLLHTAIANDLSHYVTLLVSKGSSVSLQDVAGDTAFHYAAKSHKCLEPLLAAVKKHNIPFDLNTYNYEKQAPLHLARTGQNARHLLESGADHRVRDMHGRTPLHLAAYDSRLALVAALLDYIPSKEIDATDESGNTALQIVCGGPLRQNSVEIVKLLLAKKADPNFHGAQKESAWKMSADKPELRALLLEAIAFEDGFENNSVKSELDDEIKSEPDDEIKSEPEDDYDSADEGEETSGSTALDGMGQYLGEVSSLLDRSGSWQELAGRLRLDSLLSLYCAQPSPTHTLLLHLKVYLVYCMALQQPSL
Protein: Calcium-transporting ATPase (EC 7.2.2.10) (Q95XP5)
Organism: Caenorhabditis elegans
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane {ECO:0000256|RuleBase:RU361146}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU361146}.
Interaction partners:
- Plasma membrane calcium-transporting ATPase mca-1
- Calcium-transporting ATPase
- Calcium-transporting ATPase
- Calcium-transporting ATPase
Sequence:
MPEYGASLEELRALMEYRSAEAKEKIETDYGGTTGLCERLKTDPNNGLPNNEEELERRRNVFGANEIPPHPPKCFLQLVWEALQDVTLVILLVSAIVSLALSFYRPPGEDTAGSDDSEHDAGWIEGVAILISVIVVVLVTALNDYTKERQFRGLQAKIETEHRFFVLRGGQSVQVVVNELVVGDIAQIKYGDLIPSDGIIIQSNDLKMDESSLTGESDQIRKSPEHDPIILSGTHVMEGSGKMLVTAVGVNSQTGIIMTLLGAAKTVAEEERKTAKREGGDGASGAEEGTAQALLDSKGDEAMANGKAVAAAESDGKKERSVLQAKLTRLAIQIGYAGSFVAGCTVLILIIRFCISRYAIDGKSFSLADFQHFINFLIIGVTVLVVAVPEGLPLAVTLSLAYSVKKMMLDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSFVNDVHYKDTPKIESLDQNTAKLMMDCISINSSYSSQVIPPKQLGEQATQLGNKTECGMLGFVLALGKSYQEIRDRHPEETIPKVYTFNSVRKSMSTVINLPDGGYRVFSKGASEIVTKRCKYFLGKNGTLTKFSSKDAENLVRDVIEPMASDGLRTICVAYKDYVPSSKKTADNQIAYSSEPDWENEEMIVGDMTAIAVLGIQDPVRPEVPAAITRCQEAGITVRMVTGDNINTARSIATACGILKPGEDFIALEGKEFNARIRDENGEVSQEKLDLIWPKLRVLARAQPSDKYVLVKGIIDSRVTDSREVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSIAKFLQFQLTVNVVAVVVAFVGACAIQDTPLKAVQMLWVNLIMDTLASLALATEMPTEELLKRKPYGRTSPLISRTMCKNILGHAVYQLVILFTLIFYGEVCFNIPSGRWAPLHSPPSKHFTIVFNTFVMMTLFNEINARKIHGERNIFKGLFSNPIYYVIWIATMISQVVIIQFGGRWFSTSALNTTEWLWCLAFGVGTLLWGQIVTSIPTGSLPANMTIGSGEAPTNDPLMPDYEDSDTHEKRSGQILWVRGLTRLQTQLRVVKAFRSSLEEFDERRSIASTHSVQSMRGGFWSGGGRHTTTAASPEPAGQRIAMAAITHRQSPQPYPYYHHQQPRTPSPQPHIVVENGTSSGNNGQAATAAAAAPKAETNGKTEKVPLVQQWSPDTNSSYTQTQRSINKSMSLDTPVSVAHV
Protein: Kinesin-like protein KIF2A (Kinesin-2) (P28740)
Organism: Mus musculus (Mouse)
Function: Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:9774330}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:9774330}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:9774330}. Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Lysosome {ECO:0000269|PubMed:9774330}. Note=Localized to the spindle microtubules and spindle poles from prophase to metaphase. Efficient targeting to spindle microtubules and spindle poles requires the kinase activity of PLK1. Recruited to mitotic spindles by interaction with PSRC1 (By similarity). Associated with lysosomes in NIH3T3 cells. {ECO:0000250}.
Interaction partners:
- Centrosomal protein of 170 kDa
- Serine/threonine-protein kinase PLK1
- Centromere-associated protein E
- Kinesin-like protein KIF18A
- Cell division cycle protein 20 homolog
- Ninein
- Dynactin subunit 1
- Kinesin-associated protein 3
- Kinesin-like protein KIF2C
- Kinesin-like protein KIF2B
Sequence:
MATANFGKIQIGIYVEIKRSDGRIHQAMVTSLNEDNESVTVEWIENGDTKGKEIDLESIFSLNPDLVPDEDIEPSPELPPPSSSSKVNKIVKNRRTVAAVKNDPPPRDNRVVGSARARPSQLPEQSSSAQQNGSVSDISPVQAAKKEFGPPSRRKSNCVKEVEKLQEKREKRRLQQQELREKRAQDVDATNPNYEIMCMIRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKETQMKDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKTHTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEGAEINKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRVKELTVNPAAAGDVHPIMHHPPSQIDDLETQWGVGSSPQRDDLKLLCEQNEEEVSPQLFTFHEAVSQMVEMEEQVVEDHRAVFQESIRWIEDEKALLEMTEEVDYDVDSYATQLEAILEQKIDILTELRDKVKSFRAALQEEEQASKQINPKRPRAL