wanglab/gogpt-training-data huggingface dataset:
Protein: GRUNGE (Q9NHX6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAASTQGEIRVGPGHQVNDVYAKLPDYNPISSFPIDKETDERELEESRWSPGVVADGDLLMFLRAARSMAAFQGMCDGGLEDGCLAASRDDTPINALDVLHDSGYDPGKALQALVKCPVSKGIDKKWTEGETKKFIKGLRQFGKNFFRIHKDLLPHKDTPELVEFYYLWKKTPGANNNRPHRRRRQSALRRNRVTRANNSNSNTPPKKEDTPEPQTATTATAAATAASETASRSSPAVSKEENSSLTEDDASECDSDSSLTHKRDESPSRMRTRNKQQNNNSSTSSGNNTAGNGGGNATSISSGSTGGGAAGGNSSSKDQSANAVANGKRPKRGSETPDVSGGASVDSPKTPTKAVAESSANKRKGGKQDTPNKKKRTEQESNEPSAHEENAIKEKRKRPDSPVESMNSDSRPDSVLDDGESNTTDTTTAEQQSTKDSKETVSCKEEREMVTNDLEAKAEEKAIKAEALAEDSKDSAIKNMDEETNIQAPSSADTSLVDGPNPNALPSPVAAPITMKVPTIATVEALNASVDRKEAIEKMESCDSDPEMLKKLATIKQEVSPQQQQHMQQQSQQQMQQQLAPVGIPQPPSCPPSESVYIKKEPMEDSMDATCNQNSNEPQDLKVKIEIKNEDALKHSAGGLPPSGPCAPPSALHPLSGAPVESGQEPLHLQHMPHGQVTTQPPPGYLIDGQLKYGPSGQGVPPQPPQLHSDAAGGVSGAPPGAPTTPQKYPPEMEMKFAPQDLKYPPPPPLDALKYSQEMQAAAAAAAAAGKYDMKYMMEQQGKYNVELSAAHQPPSKPGYQDSLKIPDIKPGFGHLPHNVGSPLDAAHKYGPPPTSQESQQQQPQPPAHQVPPGATPPPGIAMPKPHYQHDVQTPPLGRPFEPTGLMLKYGDPLAAKCGPPQDLKYPMPPVSQAGPADVKPYGGENLIKSSPYGPPPESPIDASARSTPGQDSQGSNSNSQPPSMPPQPQQFQSPHPSPHMPSPAGGGLPPGMHPQNLIHGPPPGAAGGSGPQPPPPPTSLHQPTPTSAGPPSLQHGLHPGHQHSQLSVASSIPPSSIGIPPTLSTMAPSHMHPHLHPHAHLQGLHRPHDLPPSMHPHAPMPLSLQGHPQHGHGLPPSHTSQQQQQQQQQQQPGGPAGTVRTSSPAQQPPRSMHDPQSSREPPTSQPSTTMAGSSGPGGPPPQQSPHAHRTSPLPGLAGSGPPPPGLIGHPMAIHPHLAHLPPGHPAHAALAHPGHHLLSHSIAGLGPGGGPIALLAGPGGLGGIPESALSRRTPPSHLPHSHASSAPLTAHSVASMTSTSMSLTTSTVPSSAFSRASPSVQISSSGGGPSGPGSVGPGGMPNSSAAAAAAAAAHRAASPASSVSSLSRQSPLHPVPQSPLSHHPSSSALSAAAAAVAERDRHALMRQQSPHMTPPPVSNASLMASPLSKMYAPQPGQRGLGTSPPPHLRPGASPPVIRHPQMPLPLPLIAPGGGIPQIGVHPGQSPYPHPLLHPSVFYSPHHHPFNSPYGYAPYGPGFPAYMKPPPQPGQLDPAAVMAAHHAGLQGPPPQQMRQDEQNAAAAAAQAAAEKQHQAAAAAAAQQHKAPQQQQPGGMPPNKPPTPKTPQGPGGGMPPGMGGPGTPTGLPPGAYPGSHMPGYPQGPPHGSPFAPQDGQPHGLKPTSHMDALRAHAHSANSAGMGGGHHPTEPLPIDIEPDPEPEIPSPTHNIPRGPSPEAKPDDTECHRSQSAIFVRHIDRGDYNSCTRTDLIFKPVADSKLARKREERDRKLAEKERERRQQQQQQQQQQQQQQAAAAQQAAQQAKMKAELKPPYADTPALRQLSEYARPHVAFRELEEIKNAQAAAASQSRLDPHWMEYYRRGIHPSQFPLYANPAISQMERERLGIPPPHHVGLDPGEHMVRMPQPPEAGFQLPPNVGQYPRPNMLIPREPHSDVLLRMSYADQLQAAEFQRQSLHDQYFRQRPR
Protein: Uncharacterized protein YggR (P52052)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Putative type II secretion system protein F
- Protein transport protein HofC homolog
- Prepilin peptidase PppA
- DNA utilization protein HofQ
- Pyruvate kinase II
Sequence:
MNMEEIVALSVKHNVSDLHLCSAWPARWRIRGRMEAAPFDTPDVEELLREWLDDDQRAILLENGQLDFAVSLAENQRLRGSAFAQRHGISLALRLLPSHCPQLEQLGAPTVLPELLKSENGLILVTGATGSGKSTTLAAMVGYLNQHADAHILTLEDPVEYLYASQRCLIQQREIGLHCMTFASGLRAALREDPDVILLGELRDSETIRLALTAAETGHLVLATLHTRGAAQAVERLVDSFPAQEKDPVRNQLAGSLRAVLSQKLEVDKQEGRVALFELLINTPAVGNLIREGKTHQLPHVIQTGQQVGMITFQQSYQHRVGEGRL
Protein: T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (Chaperonin containing TCP1 subunit 3) (P48605)
Organism: Drosophila melanogaster (Fruit fly)
Function: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
Subcellular location: Cytoplasm.
Interaction partners:
- T-complex protein 1 subunit delta
- T-complex protein 1 subunit theta
- T-complex protein 1 subunit alpha
- T-complex protein 1 subunit beta
- T-complex protein 1 subunit epsilon
- T-complex protein 1 subunit eta
- Chaperonin containing TCP1 subunit 6
- Heat shock protein 83
- Phosducin-like protein 2
- Vig2, isoform B
Sequence:
MFGGQQPILVLSQNTKRESGRKVQLENIQAGKAIADVIRTCLGPQAMLKMLMDPMGGIVMTNDGNAILREITVQHPAAKSMIEIARTQDEEVGDGTTSVIVLAGEMLAAAEPFLQQQIHPTVIIRAYREALEDIVGHLQSQLSIQLDVKDKAKMADVVKACVGTKFIGKWSDLAVKIALDAVETVTLSENGRLEVDIKRYAKVEKIPGGAIEESCVLKGVMINKDVTHPKMRRLIENPRIVLLDCSLEYKKGESQTNVEIIGEQDFTRMLQIEEEFVQRICADIIAVKPDLVFTEKGVSDLAQHYLLKAGITAIRRLRKTDNLRIARACGATIVNRTEELTEKDVGTGAGLFEVKKIGDEYFTFVTECKEPKACTILLRGASKDILNETERNLQDALHVARNLVLEPRLVAGGGAVEMAASQLLTRKQVKGPYTAVAHALEIIPRTLAQNCGANTIRALTALRAKHASHTGDGVCAWGIDGESGEIVDMNVKNIWEPLAVKLQTYKTAVETAILLLRIDDIVSGSKKRGGNEPTNPAAMAQGQE
Protein: Homoserine dehydrogenase (HDH) (EC 1.1.1.3) (Q5AIA2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Homoserine kinase
- Threonine synthase
- Aspartate-semialdehyde dehydrogenase
- Aspartokinase
- Homoserine O-acetyltransferase
- Acetolactate synthase regulatory subunit
- 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
- Branched-chain-amino-acid aminotransferase
- Branched-chain-amino-acid aminotransferase
- S-adenosylmethionine-homocysteine S-methyltransferase
Sequence:
MSKSVNVAIIGSGVVGSSYLSQLNNLKSNIAFNVIYLAKTSEEALYSKDYSPVDLSTYETAPTQPTLSLDDLVKFIKGAKKPTVLVDNTSSPAIANYYPTFIKEGISIATPNKKAFSSDLKEWKEILQTAELPGAGLVYHECTVGAALPIISPLKDLIATGDKVDKIEGIFSGTLSYIFNEFSKTEKSDVKFSDVVKKAKELGYTEPDPRDDLNGLDVARKVTILARISGLEVEGPTSFPVESLIPKELECVESVAEFMEKLPNYDADIQKVKDEAFAENKVLRFVGKVDLNTNKVSVEIGKYGFDHPFASLKGSDNVVSIKTGRYPNPLIVQGAGAGAEITAHGVLADTIKIAERIAN
Protein: Guanylate cyclase activator 2B [Cleaved into: Uroguanylin (UGN)] (P70668)
Organism: Rattus norvegicus (Rat)
Function: Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport.
Subcellular location: Secreted.
Interaction partners:
- Guanylyl cyclase C
- Guanylin
- Guanylate cyclase 2D
- Na
Sequence:
MSGSQLWAAVLLLLVLQSAQGVYIKYHGFQVQLESVKKLNELEEKQMSDPQQQKSGLLPDVCYNPALPLDLQPVCASQEAASTFKALRTIATDECELCINVACTGC
Protein: G-box-binding factor 2 (bZIP transcription factor 54) (AtbZIP54) (P42775)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds to the G-box motif (5'-CCACGTGG-3') of the rbcS-1A gene promoter. G-box and G-box-like motifs are cis-acting elements defined in promoters of certain plant genes which are regulated by such diverse stimuli as light-induction or hormone control. GBF2 is found to bind asymmetrically to the G-box.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:1373374}.
Interaction partners:
- AT1G01800 protein
- Peptidyl-prolyl cis-trans isomerase CYP23
- Choline transporter-like protein
- Chromatin modification-related protein EAF1 A
- ABSCISIC ACID-INSENSITIVE 5-like protein 8
- La-related protein 1C
- Kinase with adenine nucleotide alpha hydrolases-like domain-containing protein
- Ubinuclein-1
- bZIP transcription factor 18
- At4g37190
Sequence:
MGSNEEGNPTNNSDKPSQAAAPEQSNVHVYHHDWAAMQAYYGPRVGIPQYYNSNLAPGHAPPPYMWASPSPMMAPYGAPYPPFCPPGGVYAHPGVQMGSQPQGPVSQSASGVTTPLTIDAPANSAGNSDHGFMKKLKEFDGLAMSISNNKVGSAEHSSSEHRSSQSSENDGSSNGSDGNTTGGEQSRRKRRQQRSPSTGERPSSQNSLPLRGENEKPDVTMGTPVMPTAMSFQNSAGMNGVPQPWNEKEVKREKRKQSNRESARRSRLRKQAETEQLSVKVDALVAENMSLRSKLGQLNNESEKLRLENEAILDQLKAQATGKTENLISRVDKNNSVSGSKTVQHQLLNASPITDPVAAS
Protein: Pentatricopeptide repeat-containing protein At3g13150 (Q9LK58)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At2g20720
- Pentatricopeptide repeat
- Endoplasmic reticulum transmembrane protein
- Vacuolar protein sorting-associated 9A-like protein
- Pentatricopeptide repeat-containing protein At1g02370
- H/ACA ribonucleoprotein complex non-core subunit NAF1
- Transcription factor EMB1444
- Pentatricopeptide repeat-containing protein At1g06270
- At5g17180
- Endoplasmic reticulum transmembrane protein
Sequence:
MSKVGSSLYSRLHGIFKESSIATAKSAKPRSQTKSTKFPSKLKASTASVGDGGQSSNDAKDSKNSKLTQKVEKFKRSCESESFRQVHGLYSAFIRRLREAKKFSTIDEVLQYQKKFDDIKSEDFVIRIMLLYGYSGMAEHAHKLFDEMPELNCERTVKSFNALLSAYVNSKKLDEAMKTFKELPEKLGITPDLVTYNTMIKALCRKGSMDDILSIFEELEKNGFEPDLISFNTLLEEFYRRELFVEGDRIWDLMKSKNLSPNIRSYNSRVRGLTRNKKFTDALNLIDVMKTEGISPDVHTYNALITAYRVDNNLEEVMKCYNEMKEKGLTPDTVTYCMLIPLLCKKGDLDRAVEVSEEAIKHKLLSRPNMYKPVVERLMGAGKIDEATQLVKNGKLQSYFRYLPDLSAGKKKTTSSPVSSSAKTTSTPVSSSPDTSSFLLSLSLAADSSSSDSDSSSPDSSSSVSSSPDSSSSVSSSPDSYSSFSSSPDSSSSVSSSLFSSSRENSSSPDYSNSVSSSLDYSGSVSSSSDYSSSVFPSANSSSSSSGLLDD
Protein: Sulfite reductase [ferredoxin], chloroplastic (GmSiR) (EC 1.8.7.1) (Nucleoid DNA-compacting protein of 68 kDa) (Q9AWB2)
Organism: Glycine max (Soybean) (Glycine hispida)
Function: Essential protein with sulfite reductase activity required in assimilatory sulfate reduction pathway during both primary and secondary metabolism and thus involved in development and growth.
Subcellular location: Plastid, chloroplast stroma, chloroplast nucleoid. Plastid, chloroplast stroma. Plastid stroma {ECO:0000250}.
Interaction partners:
- adenylyl-sulfate reductase
- adenylyl-sulfate reductase
- adenylyl-sulfate reductase
- sulfate adenylyltransferase
- uroporphyrinogen-III C-methyltransferase
- uroporphyrinogen-III C-methyltransferase
- FAD synthase
- FAD synthase
- Adenylyl-sulfate kinase
- Adenylyl-sulfate kinase
Sequence:
MTTSFGPATTSAPLKDHKVQIPSFHGLRSSSASALPRNALSLPSSTRSLSLIRAVSTPAQSETATVKRSKVEIFKEQSNFIRYPLNEDILTDAPNISEAATQLIKFHGSYQQYNREERGSRSYSFMIRTKNPCGKVSNQLYLTMDDLADQFGIGTLRLTTRQTFQLHGVLKKDLKTVMGTIIRNMGSTLGACGDLNRNVLAPAAPLARKDYLFAQQTAENIAALLAPQSGFYYDIWVDGEKILTSEPPEVVQARNDNSHGTNFPDSPEPIYGTQFLPRKFKIAVTVPTDNSVDILTNDIGVVVVTDDDGEPQGFNIYVGGGMGRTHRLETTFPRLAEPIGYVPKEDILYAVKAIVVTQRENGRRDDRKYSRLKYLISSWGIEKFRSVVEQYYGKKFEPFRALPEWEFKSYLGWHEQGDGKLFYGLHVDNGRIGGNMKKTLREVIEKYNLNVRITPNQNIILTDVRAAWKRPITTTLAQAGLLQPRFVDPLNITAMACPAFPLCPLAITEAERGIPNILKRIRDVFDKVGLKYSESVVVRITGCPNGCARPYMAELGLVGDGPNSYQIWLGGTP
Protein: At2g30880/F7F1.9 (Pleckstrin homology (PH) domain-containing protein) (Q8VYJ6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Root phototropism protein 2
- U-box domain-containing protein 20
- Protein RESTRICTED TEV MOVEMENT 3
- KH domain-containing protein At2g38610
- Brefeldin A-inhibited guanine nucleotide-exchange protein 5
- Serine/threonine-protein phosphatase BSL3
Sequence:
MASNGASPRIVDATENSLDKIKRQLASGSGRNLLQGPLFKRSETLRKWNERWVILDPTTGKMEYKTRRNEPTIKGTILFDENSTISISPVNFQGLPKYNGCCIYIGTPQKKDYFLCAETPGAAKAWVTTLHATQLVLKAHKEAVESLSGSGSATLGTVATVVAAANSTALECSREIQAAMQISLRNALKITPNKPIDGPLDDLTIMKETLRVKDEELHNLARELRSRDSMIKEIADKLSETAEAAVAAASAAHTMDEQRKIVCVEFERLTTDSQRQQEATKLKLKELEEKTFTLSKEKDQLVKERDAALQEAHMWRSELGKARERVVILEGAVVRAEEKVRVAEASGEAKSKEASQREATAWTEKQELLAYVNMLQTQLQRQQLETKQVCEEKTESTNGEASLPMTKETEKNVDKACLSISRTASIPGENVVHMSEEQVVNAQPPVGENEWNDIQATEARVSDVREISAETERDRRNSLDIPVVSPEPNVPRNDPPSESFHHQP
Protein: NK2 homeobox 4a isoform 1 (Zgc:171531 protein) (A8KB41)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MSLSPKHTTPFSVTDILSPIEETYKKFSGMESTGNLTSPLGAYRQPQVSQTGMQQHSMGHNATVATTYHMPHSVSQFSHSAMGGYCNGSIANMGDLPSYQETMRNSAAATGWYGANPDPRYSTISRFMGPSTGMNMTGMGTLTGMADTTKSIPPLHAAPRRKRRVLFSQAQVCELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGNLCQQQQSPRRVAVPVLVKDGKPCQNGSNTPTPNQQQMQQQQNGGGVVLPTSSNSMNQHQSQQVNALVQAQDLEEMSPSPPSLHSQMNSMGQIDTSVDYTNNMVTSNLLYGRTW
Protein: chitinase (EC 3.2.1.14) (Q7SYA8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MTGLIFLAGISLALCQCGLASQLACYFANWSQYRPDVGKYMPSNVDPHLCTHLIYAFSVINIKNKLATSEWNDETLYQSFNALKQSNPNLKTLLAVGTLNLGSTQFSRMVSTPQKRQTFIESSIKFLRTHGFDGLDLDWEYPGSGESPPEDKHRFTLLCKELLKAYQAESKATRRPRLMLTAAVAARKGIIDAGYEIAEVSKYLDFINIMTYDFHGSWENVTGHNSPLYRDSRDTGDQIYYNTDFAMTYWRDQGAPVEKLRMGFAAYGRTFCLSSAVNGLGAPVSGPASAGTYTREAGYWSYYEICTFLQRASVEQIADQKVPYATEGLNWVGFDDQKSYETKVDYLKEKGFGGAFVWSLDLDDFSGQFCGQGKYPLIGHLHTLLNISNTEFRHLPKTIKSGGASATGNIVTTTPIVKTVTSGSDFCAGGLVGIFANPDNPMTFIQCANGRTFIQNCPAKTVFDPDCSCCNWPKN
Protein: GAD67 (Glutamate decarboxylase 1 (EC 4.1.1.15)) (Glutamate decarboxylase 1b isoform X1) (Q7ZUS3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MASSAPSSSAGDMDPNTANLRQPATTSDAWYGVAHGCTRKLGMKICGFLQKNNSLDEKSRMVGSFKESAKNQMSCDNNERFTRDETDFSNLFARDLLPAKNGEEPTIQFLLEVVEILTNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDQPESLEQILVDCRDTLKYGVRTGHPRFFNQLSSGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQLTLKKMREIIGWPNGDGDALFSPGGAISNMYSVMVARYKYFPEVKTKGMSAAPRLVLFTSEHSHYSIKKAGAVLGFGKENVILLKTDERGRVIPADLEAKVIDAKQKGYVPLFVNATAGTTVYGAFDPINDIADICEKYNLWLHVDGAWGGGLLMSRKHRHKLSGIERANSVTWNPHKMMGVPLQCSAILVREKGILQGCNSMCAGYLFQPDKQYDVTYDTGDKAIQCGRHVDIFKFWLMWKAKGTIGFEQHIDRCLELSEYLYNKIKNREGYEMVFEGQPQHTNVCFWYIPPSLRGMPNGDERREKLHRVAPKIKAMMMECGTTMVGYQPQGDKVNFFRMVVSNHAVTKSDIDFLIDEIERLGQDL
Protein: S-adenosylmethionine decarboxylase proenzyme 1 (AdoMetDC 1) (SAMDC 1) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase 1 alpha chain; S-adenosylmethionine decarboxylase 1 beta chain] (P0DMN7)
Organism: Mus musculus (Mouse)
Function: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
Interaction partners:
- Spermidine synthase
- Spermine synthase
- S-adenosylmethionine synthase isoform type-2
- S-adenosylmethionine synthase isoform type-1
- Ornithine decarboxylase
- Methionine adenosyltransferase 2 subunit beta
- DNA
- Gene model 853
- DNA
- DNA
Sequence:
MEAAHFFEGTEKLLEVWFSRQQSDASQGSGDLRTIPRSEWDVLLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFPESRVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATLFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLSSPQKIDGFKRLDCQSAMFNDYNFVFTSFAKKQQQQQS
Protein: Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein (FAU ubiquitin like and ribosomal protein S30 fusion) [Cleaved into: Ubiquitin-like protein FUBI; Small ribosomal subunit protein eS30 (40S ribosomal protein S30)] (P62861)
Organism: Homo sapiens (Human)
Function: May have pro-apoptotic activity.
Subcellular location: [Small ribosomal subunit protein eS30]: Cytoplasm {ECO:0000269|PubMed:23636399}. Nucleus {ECO:0000269|PubMed:34318747}.
Interaction partners:
Sequence:
MQLFVRAQELHTFEVTGQETVAQIKAHVASLEGIAPEDQVVLLAGAPLEDEATLGQCGVEALTTLEVAGRMLGGKVHGSLARAGKVRGQTPKVAKQEKKKKKTGRAKRRMQYNRRFVNVVPTFGKKKGPNANS
Protein: Baccharis oxide synthase (StrBOS) (EC 5.4.99.51) (B9X0J1)
Organism: Stevia rebaudiana (Stevia) (Eupatorium rebaudianum)
Function: Oxidosqualene cyclase converting (3S)-2,3-epoxy-2,3-dihydrosqualene to baccharis oxide, a triterpene with a 3,10-oxide bridge in the A-ring. Also mediates conversion of other triterpenoids at a much lower level.
Interaction partners:
Sequence:
MWRLKIADGNNNPYLYSTNNFVGRQTWEFDPNYGTQEERDEVEQARQHFWNNRHQFKATGDVLWRMQFIREKRFKQTIPQVKIEDGEEISYDKVTATLRRSVHLLAALQADDGHWPAENTGPMFFIQPLVICLYITGHLDRVFPKEHKKEILRYLYTQQNEDGGWGLHIEGQSIMFGTIMSYVCMRLLGEGPDGGLNGACTKARKWILDHGSVLASPSWGKIYLTILGVHEWEGCNPLPPEFWILPSIFPMHPAKMWCYCRLIYMPMSYLYGRRFVGPITPLVLQLREELYSQSYNDIKWKSTRHLVVKEDLHYPHPWLQDLMWDGLYIFTEPLLTRWPFSKLREKALKTTINHIHYEDENSRYITIGAVEKSLCMLACWDEDPDGVCFKKHLARIPDYIWVSEDGLKMQSFGSQLWDASLAIQALLATDLNHDIEPILRKGHDFIKASQVKDNPSGDFKSMYRHITKGSWTFSDQDHGWQTSDCTTEGLKCCLLLSKMSAEIVGEKMQPEQFYDAVNLILSLQCKNGGEAGWEPAGESNWLEFLNPSELFEDIVLEHDSVECTATGMQALVIFKKLYPKHRREEIEKFLKDACGYLEKVQMQDGSWYGEWGICFTYGTCFALGGMEAIGKTYENCEAIRRAVNFLLTTQRNDGGWGESYRSSPKKKYVPLEGNRSNLVQTACALMGLIRSKQEERDPTPLHRAAKLLINSQMENGDFPQEETGGVFKKNCLLHYPMYRNIYTLWALGEYRKKVLPQPTKV
Protein: Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33) (Q86T24)
Organism: Homo sapiens (Human)
Function: Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. May contribute to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2. Represses expression of MMP7 in conjunction with transcriptional corepressors CBFA2T3, CBFA2T2 and RUNX1T1.
Subcellular location: Nucleus {ECO:0000269|PubMed:15781635, ECO:0000269|PubMed:16354688}. Cytoplasm {ECO:0000269|PubMed:15781635}. Note=Also cytoplasmic in cells grown at high densities.
Interaction partners:
- Catenin delta-1
- Nuclear receptor corepressor 1
- Catenin delta-2
- 43 kDa receptor-associated protein of the synapse
- Transcriptional repressor CTCF
- Methyl-CpG-binding domain protein 4
- Catenin beta-1
- Nuclear receptor corepressor 2
Sequence:
MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTYFHQLFSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAELGVPLSQVKSISGTAQDGNTEPLPPDSGDKNLVIQKSKDEAQDNGATIMPIITESFSLSAEDYEMKKIIVTDSDDDDDDVIFCSEILPTKETLPSNNTVAQVQSNPGPVAISDVAPSASNNSPPLTNITPTQKLPTPVNQATLSQTQGSEKLLVSSAPTHLTPNIILLNQTPLSTPPNVSSSLPNHMPSSINLLVQNQQTPNSAILTGNKANEEEEEEIIDDDDDTISSSPDSAVSNTSLVPQADTSQNTSFDGSLIQKMQIPTLLQEPLSNSLKISDIITRNTNDPGVGSKHLMEGQKIITLDTATEIEGLSTGCKVYANIGEDTYDIVIPVKDDPDEGEARLENEIPKTSGSEMANKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYPCRYCEKVFPLAEYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQDPSGDSKLYRLHPCRSLQIRQYAYLSDRSSTIPAMKDDGIGYKVDTGKEPPVGTTTSTQNKPMTWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY
Protein: LP04985p (Mitochondrial ribosomal protein L20) (Q9VU36)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Large ribosomal subunit protein uL13m
- Small ribosomal subunit protein bS16m
- Large ribosomal subunit protein uL5
- 40S ribosomal protein S15
- Elongation factor Ts, mitochondrial
- Large ribosomal subunit protein bL21m
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS17
- FI01658p
- GM03767p
Sequence:
MVFLNLPLLVRSRGPDEFWRKRRIFKLAAHYRSRTRNVYSFAIRSVHRALAYATKGRKLKKLDMAQLWSTRVEAGCQQYGVGLETFKEGLARSDILLNKKVLSDLAIWEPRSFEALVKISRERAAVEGMPDIKRRSAFNQVYGLSNLKLD
Protein: Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.-) (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase B) (GlcNAc-T Vb) (GNT-Vb) (hGnTVb) (Mannoside acetylglucosaminyltransferase 5B) (N-acetylglucosaminyl-transferase Vb) (N-acetylglucosaminyltransferase IX) (GNT-IX) (Q3V5L5)
Organism: Homo sapiens (Human)
Function: Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAc-beta1,2-Man-alpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAc-beta1,2-Man-alpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway.
Subcellular location: Golgi apparatus membrane {ECO:0000250|UniProtKB:Q765H6}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q765H6}.
Interaction partners:
- Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
- Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
- Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1
- Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C
- Beta-1,4-galactosyltransferase 2
- Beta-1,4-galactosyltransferase 3
- Beta-1,4-galactosyltransferase 1
- Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D
- Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A
- Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
Sequence:
MITVNPDGKIMVRRCLVTLRPFRLFVLGIGFFTLCFLMTSLGGQFSARRLGDSPFTIRTEVMGGPESRGVLRKMSDLLELMVKRMDALARLENSSELHRAGGDLHFPADRMPPGAGLMERIQAIAQNVSDIAVKVDQILRHSLLLHSKVSEGRRDQCEAPSDPKFPDCSGKVEWMRARWTSDPCYAFFGVDGTECSFLIYLSEVEWFCPPLPWRNQTAAQRAPKPLPKVQAVFRSNLSHLLDLMGSGKESLIFMKKRTKRLTAQWALAAQRLAQKLGATQRDQKQILVHIGFLTEESGDVFSPRVLKGGPLGEMVQWADILTALYVLGHGLRVTVSLKELQSNLGVPPGRGSCPLTMPLPFDLIYTDYHGLQQMKRHMGLSFKKYRCRIRVIDTFGTEPAYNHEEYATLHGYRTNWGYWNLNPKQFMTMFPHTPDNSFMGFVSEELNETEKRLIKGGKASNMAVVYGKEASIWKLQGKEKFLGILNKYMEIHGTVYYESQRPPEVPAFVKNHGLLPQPEFQQLLRKAKLFIGFGFPYEGPAPLEAIANGCIFLQSRFSPPHSSLNHEFFRGKPTSREVFSQHPYAENFIGKPHVWTVDYNNSEEFEAAIKAIMRTQVDPYLPYEYTCEGMLERIHAYIQHQDFCRAPDPALPEAHAPQSPFVLAPNATHLEWARNTSLAPGAWPPAHALRAWLAVPGRACTDTCLDHGLICEPSFFPFLNSQDAFLKLQVPCDSTESEMNHLYPAFAQPGQECYLQKEPLLFSCAGSNTKYRRLCPCRDFRKGQVALCQGCL
Protein: Protein disulfide-isomerase (EC 5.3.4.1) (Q95T75)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum lumen {ECO:0000256|ARBA:ARBA00004319}.
Interaction partners:
Sequence:
MRAQVGPASKTVRTVAELKKFLDTKDTTLFGYFSDSDSKLAKIFLKFADKNREKYRFGHSSEKEVLDKQGETDKIVLIRAPHLSNKFESSSIKFEGSSESDLSTFVKENFHGLVGHRTQDSVKDFQNPLITAYYSVDYQKNPKGTNYWRNRVLKVAKEFVGQINFAIASKDDFQHELNEYGYDFVGDKPVVLARDEKNLKYALKDEFSVENLQDFVEKLLANELEPYIKSEPIPESNDAPVKVAVAKNFDDLVINNGKDTLIEFYAPWCGHCKKLSPIYEELAEKLQDEDVAIVKMDATANDVPPEFNVRGFPTLFWLPKDAKNKPVSYNGGREVDDFLKYIAKEATTELKGFDRSGKPKKTEL
Protein: Small ribosomal subunit protein uS13A (40S ribosomal protein S18-A) (P0CT66)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS14
- Small ribosomal subunit protein eS7
- Elongation factor 3
- mRNA export factor elf1
- Small ribosomal subunit protein eS27
- Small ribosomal subunit protein eS21
Sequence:
MSLVVPDNFQHILRLLNTNVDGKVKVMFAMTQIKGVGRRYANIVCKKADIDMSKRAGELTTEELERIVTIIQNPSQFKIPSWFLNRQKDINDGKSFQLLANNVDSKLREDLERLKKIQTHRGLRHALDLRVRGQHTKTTGRRGKTVGVSKKK
Protein: Mitochondrial ribosomal protein S34 (C9JJ19)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MARKKVRPRLIAELARRVRALREQLNRPRDSQLYAVDYETLTRPFSGRRLPVRAWADVRRESRLLQLLGRLPLFGLGRLVTRKSWLWQHDEPCYWRLTRVRPDYTAQNLDHGKAWGILTFKDASFSSSGKTESEAREIEHVMYHDWRLVPKHEEEAFTAFTPAPEDSLASVPYPPLLRAMIIAERQKNGDTSTEEPMLNVQRIRMEPWDYPAKQEDKGRAKGTPV
Protein: Assembly factor cbp4 (Cytochrome b mRNA-processing protein 4) (Q9USV6)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Interaction partners:
- CBP3-like protein
- Cytochrome b-c1 complex subunit 9
- Cytochrome b-c1 complex subunit 8
- Cytochrome b-c1 complex subunit 7
- Cytochrome b
Sequence:
MNRVVKSIVYGVGIVGFGYMTMKLTTPSPERVVNSLPPDLRASYEMNKKDRSQAEGVLRMIEDAKRNPKNLV
Protein: Uncharacterized family 31 glucosidase C1039.11c (EC 3.2.1.-) (Q9URX4)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Spore wall {ECO:0000269|PubMed:10759889}. Note=Spore rim.
Interaction partners:
- Alpha-glucosidase
- Putative beta-glucosidase
- Probable glucoamylase
- Hexokinase-1
- Alpha-galactosidase mel1
- Hexokinase-2
- Putative invertase
- Invertase
- Glucan 1,3-beta-glucosidase
- Uncharacterized family 31 glucosidase C30D11.01c
Sequence:
MFIHRMKSNLASLFLSFFLLLACEFTFSYADFSTTTSDATHPSATATEDIFSTPAVPSLGLAQNPSVYEPYRGDKCGGYNAIQVSEYEKGVLAILQLNGDPCYAYGTDYPFLALNVSFDSIDRLHVSIQDLYGAQFQFSKRTDVWDAPLYHFQPQFGDRTYNFSFNSQPFEFWVTRVSDGEVLFDTRGHKLIFEDQYIELTTNMVDDYNVYGLAETVHGLRLGNNLTRTFWANGNPTPLDRNAYGTHPFYLEHRYTPSENLNSDGQPSYTSSTHGVLMLTANGMEVLLRPNYLQYRIIGGIVDLYIYVGGTKNPKDTVSQFVQSVGTPAMQQHWTFGFHICRWGYKNVFDLVEVKENFKNFEIPVDTFWSDIDYMYEYRDFTVESNAFPKDKMMEFFNSLQQSNQHYVPIIDAAIYAANPINRSDDVYYPYYEGVRRDIFLRNPDRSLYVGNVWPGFTTFPDFTNPETTNYWTECLMNLSAAFGYNSSFPLPYSGLWIDMNEPTSFCIGSCGTDKLDQNPVHPAFILEGEPNNMVYMYPEGFEHTNASEHASAYQASVSQYYATATSTVESVKATSTPLNVRPKYNINYPPYALNTEQGEGDLSNLGVSVNATYHDGTVRYNLFNTYGYDQSRVTYDSLTSIEPNVRPFILSRSTFVGSGKYAAHWLGDNYSLWSNMIFSIPGALTFNMVGLPMVGADVCGFMGNTDEELCSRWMALGAFLPFYRNHNSLGSISQEPYRWESVAESSRCAMNIRYSLLPYWYTLMYEASSQGLPLIRPLFFEFPNEPSLANADRQFMVGSALLVTPVLEPNVDYVRGVFPGDNSTIWYDWYDHKVIYRQHNENITLSAPLTHINVAIRGGNIIPMQKPSLTTHETKQNPYDLLVALDSDRKACGSLYVDDGVSIQQESTLFVKFVANGDSLSIESYGDLQVHEPLSKITIIGLPCAPIGVYFEGVQVESFSYLEDTKELVLTNLEAFTSTGAFSNNWTISWNLPV