wanglab/gogpt-training-data huggingface dataset:
Protein: Hemoglobin subunit delta (Delta-globin) (Hemoglobin delta chain) (P02042)
Organism: Homo sapiens (Human)
Function: Involved in oxygen transport from the lung to the various peripheral tissues.
Interaction partners:
- Hemoglobin subunit alpha
- Alpha-hemoglobin-stabilizing protein
- Hemoglobin subunit theta-1
- Hemoglobin subunit zeta
- Hemoglobin subunit mu
- Hemoglobin subunit beta
- Hemoglobin subunit gamma 1
- Hemoglobin subunit gamma-2
- 5-aminolevulinate synthase, erythroid-specific, mitochondrial
- Protein 4.2
Sequence:
MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFGKEFTPQMQAAYQKVVAGVANALAHKYH
Protein: Pentatricopeptide repeat-containing protein At2g33680 (P93005)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Putative defensin-like protein 148
- Putative F-box protein At2g33655
- Poly
- 187-kDa microtubule-associated protein AIR9
- Poly
Sequence:
MHPSTFQTELNPHTSTLLKKLTHHSQQRNLVAGRAVHGQIIRTGASTCIQHANVLVNFYAKCGKLAKAHSIFNAIICKDVVSWNSLITGYSQNGGISSSYTVMQLFREMRAQDILPNAYTLAGIFKAESSLQSSTVGRQAHALVVKMSSFGDIYVDTSLVGMYCKAGLVEDGLKVFAYMPERNTYTWSTMVSGYATRGRVEEAIKVFNLFLREKEEGSDSDYVFTAVLSSLAATIYVGLGRQIHCITIKNGLLGFVALSNALVTMYSKCESLNEACKMFDSSGDRNSITWSAMVTGYSQNGESLEAVKLFSRMFSAGIKPSEYTIVGVLNACSDICYLEEGKQLHSFLLKLGFERHLFATTALVDMYAKAGCLADARKGFDCLQERDVALWTSLISGYVQNSDNEEALILYRRMKTAGIIPNDPTMASVLKACSSLATLELGKQVHGHTIKHGFGLEVPIGSALSTMYSKCGSLEDGNLVFRRTPNKDVVSWNAMISGLSHNGQGDEALELFEEMLAEGMEPDDVTFVNIISACSHKGFVERGWFYFNMMSDQIGLDPKVDHYACMVDLLSRAGQLKEAKEFIESANIDHGLCLWRILLSACKNHGKCELGVYAGEKLMALGSRESSTYVQLSGIYTALGRMRDVERVWKHMRANGVSKEVGCSWIELKNQYHVFVVGDTMHPMIEETKDLVCLVSRQMIEEGFVTVLDSSFVEEEEGTQLSTSFII
Protein: NAC domain-containing protein 79 (ANAC79) (ANAC80) (AtNAC79) (AtNAC80) (Q9FLR3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00353}.
Interaction partners:
- Jasmonate-induced oxygenase 1
Sequence:
METFGVFHKEDDEQMDLPPGFRFHPTDEELITHYLHKKVLDLGFSAKAIGEVDLNKAEPWELPYKAKIGEKEWYFFCVRDRKYPTGLRTNRATQAGYWKATGKDKEIFRGKSLVGMKKTLVFYRGRAPKGQKTNWVMHEYRLDGKLSAHNLPKTAKNEWVICRVFHKTAGGKKIPISTLIRIGSYGTGSSLPPLTDSSPYNDKTKTEPVYVPCFSNQAETRGTILNCFSNPSLSSIQPDFLQMIPLYQPQSLNISESSNPVLTQEQSVLQAMMENNRRQNFKTLSISQETGVSNTDNSSVFEFGRKRFDHQEVPSPSSGPVDLEPFWNY
Protein: Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.4.19.12) (Deubiquitinating enzyme 21) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (B2GUX4)
Organism: Rattus norvegicus (Rat)
Function: Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination. Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates. Deubiquitinates BAZ2A/TIP5 leading to its stabilization.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9UK80}. Nucleus {ECO:0000250|UniProtKB:Q9UK80}.
Interaction partners:
- Receptor-interacting serine/threonine-protein kinase 1
- Polyubiquitin-C
- Ubiquitin-ribosomal protein eL40 fusion protein
- GATA-binding protein 3.
- Ubiquitin-ribosomal protein eS31 fusion protein
- Interleukin-33
Sequence:
MPQASEHRLGRTREPPVNVQPRVGAKIPFPPRARSKERRNPVPGPNSMLRPLPPRPGPPDERLKKLDLGRGRTSGSRPRGPLRADHGVPLPGSPPPTVALPLPSRTNLTRSKSVSSGDLRPMGIALGGHRGTGELGAALSRLALRPEPPTLRRSTSLRRLGGFPGPPTLLSIRTEPPPSHGSFHMISARPSEPFYSDDKMAHHTLLLGSGHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGGGRAQELTEAFADVIGALWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPILASGPVPSPPRRGGALHEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSTSRGSIKKSSVGVDFPLQRLSLGDFASDKVGSPVYQLYALCNHSGSVHYGHYTALCRCQTGWHVYNDSRVSPVSENQVASSEGYVLFYQLMQEPPRCL
Protein: Damage response protein 1 (Q12091)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Lanosterol 14-alpha demethylase CYP51
- Cytochrome b5
Sequence:
MSFIKNLLFGGVKTSEDPTGLTGNGASNTNDSNKGSEPVVAGNFFPRTLSKFNGHDDEKIFIAIRGKVYDCTRGRQFYGPSGPYTNFAGHDASRGLALNSFDLDVIKDWDQPIDPLDDLTKEQIDALDEWQEHFENKYPCIGTLIPEPGVNV
Protein: Transcription factor 12 (H0YNQ5)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYY
Protein: Sec24d protein (Q8R0M3)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000256|ARBA:ARBA00004299}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004299}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004299}. Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004397}.
Interaction partners:
Sequence:
KKLVNTDKEKILFQPQTAVYESLAKDCVANSCSVTLFLFPSQFVDVASLGLVPLLTGGTLYKYNVFQIHSDSQRFLTDLRNDIEKKIGFDAIMRVRTSTGFRATDFFGGIFMNNTTDVEMAAIDCDKAVTVEFKHDDKLSEDVGALIQCAVLYTTISGQRRLRIHNLALNCSTQLADLYKSCETDALINFFAKSAFKAVLNQPLKAIREILVNQTAHMLACYRKHCASPSAASQLILPDSMKVLPVYMNSLLKNCVLLSRSEISPDERAYQRQLVMTMGVADSQLFFYPLLLPIHTLDVKSAALPPAVRCSESRLSEEGIFLLANGLNMFLWFGVGSPPELIQGIFNVPSFAHINTDMTSLPEVGSPHSQQLRMIMNNIQQKKPYSMKLIVVKQREQREMAFRQFLVEDKGLYGGSSYVDFLCCVHKEICQLLN
Protein: Hydroxycarboxylic acid receptor 1-4 (Oxoeicosanoid receptor 1) (F1QUW3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Hydroxycarboxylic acid receptor 1-3
Sequence:
MSNITSCMEPHSFISSILKPIFILELILGLPGNVFALWILFFKSPWKACNVYFFSLVIADLLLLTGMPFRIDYFFRGEDWIFGESICRLVLYVISVNSSASVAFMTILAVDRFFRILYPHHRICRMNVKQGLMLSSMTWVIVLLLRLPSALSPVLTSHKNSSKLTCHSFLSWTSPSVQMRIYNSVQLIEVLVAFTLVVFCLVRVFSNTNIRQSKGPHRRVKRAVRLLFIFVIIFVLCFLPTVIFGNFLQVFPCSESLIVCLHASLALSYMNSALDPVIYCHINAWFRDTLKGKSNSLGMTKFKMSAKTNKKP
Protein: Midkine (MK) (Q9W767)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU369117}.
Interaction partners:
- Tyrosine-protein kinase receptor
- ALK tyrosine kinase receptor
Sequence:
MRGLFSTLLVVLVALMIVTSEAGKNKKEKNKGGKGGADCAEWLYGSCVANNGDCGQGMREGTCNEQTRKVKCRVPCNWKKEFGADCKYKFGNWGECDAATSTKSRTGTLQKALFNVECQQTVSVTKPCTTKVKNKPKGKKGKGKGN
Protein: Protein IVY1 (Interaction with VPS33 and YPT7 protein 1) (Q04934)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May be required for vacuolar fusion. Overexpression leads to fragmentation of vacuoles, missorting of the vacuolar enzyme carboxypeptidase Y (CPY) to the exterior of the cell and accumulation of multivesicular bodies inside the cell.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:12553664}; Peripheral membrane protein {ECO:0000269|PubMed:12553664}. Note=Binds to various phospholipids.
Interaction partners:
- Ypt/Rab-type GTPase YPT7
- Vacuolar protein sorting-associated protein 33
- V-type proton ATPase subunit a, vacuolar isoform
- GTP-binding protein GTR2
- T-complex protein 1 subunit eta
- GTP-binding protein GTR1
Sequence:
MPDNNTEQLQGSPSSDQRLRVDWDNGNHFDVSPDRYAPHLSEFYPIVNSKRPVASSAGSENNDHLDDMNHLRSSKVYSKARRASSITSGTSTINDLQTLITKRDVKETQEALSTLLRNSNAYSDSLLKTSQNGAEIAHSLENIAKLKGCNDETAEKLLSASGLFYLLSNHQLIMSKYFNDLLGDNLIDDIDEFELQTKIMENKFKAQSKEQSLKLKLQERHNFDISKRKIRNLISYRESLSSLQARLDQLETLKHDFYMDSYELVENTCNKVLSKVATVSRAQVEISENIARKGWSGGGLDELLCDADDPFSKKADGPYGTIGGDGETAGEAYNSDEETGGNDVVLNELLEGTSQPSTSKTSLPKSKGSSTVSTPNHSQSSSNKDGVRNNGGGKNGEDEDTDNLMGTENSFSLPPTRNSAEETTQTFKQLSIKEDNDNHSSDTDGMQDQSSNI
Protein: 4-dimethylallyltryptophan N-methyltransferase (EC 2.1.1.261) (4-dimethylallyltryptophan methyltransferase) (B6D5I7)
Organism: Aspergillus fumigatus (Neosartorya fumigata)
Function: Methyltransferase that mediates the second step of biosynthesis of ergot alkaloid biosynthesis. Catalyzes the N-methylation of 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of 4-dimethylallyl-L-abrine. Ergot alkaloids, which are produced by endophyte fungi, can enhance plant host fitness, but also cause livestock toxicosis to host plants.
Interaction partners:
Sequence:
MTISAPPIIDIRQAGLESSIPDQVVEGLTKEVKTLPALLFYSTKGIQHWNRHSHAADFYPRHEELCILKAEASKMAASIAQDSLVIDMGSASMDKVILLLEALEEQKKSITYCALDLSYSELASNFQAIPVDRFHYVRFAALHGTFDDGLHWLQNAPDIRNRPRCILLFGLTIGNFSRDNAASFLRNIAQSALSTSPTQSSIIVSLDSCKLPTKILRAYTADGVVPFALASLSYANSLFHPKGDRKIFNEEDWYFHSEWNHALGRHEASLITQSKDIQLGAPLETVIVRRDEKIRFGCSYKYDKAERDQLFHSAGLEDAAVWTAPDCDVAFYQLRLRLN
Protein: Menin (O00255)
Organism: Homo sapiens (Human)
Function: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.
Subcellular location: Nucleus {ECO:0000269|PubMed:12874027}. Note=Concentrated in nuclear body-like structures. Relocates to the nuclear matrix upon gamma irradiation.
Interaction partners:
- Histone-lysine N-methyltransferase 2A
- Transcription factor JunD
- PC4 and SFRS1-interacting protein
- Retinoblastoma-binding protein 5
- WD repeat-containing protein 5
- Set1/Ash2 histone methyltransferase complex subunit ASH2
- Mothers against decapentaplegic homolog 3
- Catenin beta-1
- Histone-lysine N-methyltransferase 2B
- Histone-lysine N-methyltransferase 2D
Sequence:
MGLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGEERPGEQSQGTQSQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVRIVSREAEAAEAEEPWGEEAREGRRRGPRRESKPEEPPPPKKPALDKGLGTGQGAVSGPPRKPPGTVAGTARGPEGGSTAQVPAPTASPPPEGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL
Protein: Laminin subunit gamma-1 (Laminin B2 chain) (Laminin-1 subunit gamma) (Laminin-10 subunit gamma) (Laminin-11 subunit gamma) (Laminin-2 subunit gamma) (Laminin-3 subunit gamma) (Laminin-4 subunit gamma) (Laminin-6 subunit gamma) (Laminin-7 subunit gamma) (Laminin-8 subunit gamma) (Laminin-9 subunit gamma) (S-laminin subunit gamma) (S-LAM gamma) (P11047)
Organism: Homo sapiens (Human)
Function: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane.
Interaction partners:
- Laminin subunit alpha-5
- Laminin subunit beta-1
- Nidogen-1
- Nidogen-2
- Integrin beta-1
- Laminin subunit alpha-2
- Laminin subunit alpha-4
- Integrin alpha-6
- Laminin subunit beta-2
- Laminin subunit alpha-1
Sequence:
MRGSHRAAPALRPRGRLWPVLAVLAAAAAAGCAQAAMDECTDEGGRPQRCMPEFVNAAFNVTVVATNTCGTPPEEYCVQTGVTGVTKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQSQTMLAGVQYPSSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFSTLEGRPSAYNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGSLSTQCDSYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTNAVGYSVYSISSTFQIDEDGWRAEQRDGSEASLEWSSERQDIAVISDSYFPRYFIAPAKFLGKQVLSYGQNLSFSFRVDRRDTRLSAEDLVLEGAGLRVSVPLIAQGNSYPSETTVKYVFRLHEATDYPWRPALTPFEFQKLLNNLTSIKIRGTYSERSAGYLDDVTLASARPGPGVPATWVESCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCPCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGFGPEGCKPCDCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPACYRLVKDKVADHRVKLQELESLIANLGTGDEMVTDQAFEDRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAEQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTGDPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLENEANNIKMEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKKGRDTLQEANDILNNLKDFDRRVNDNKTAAEEALRKIPAINQTITEANEKTREAQQALGSAAADATEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMASQAAQEAEINARKAKNSVTSLLSIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEMKVSDLDRKVSDLENEAKKQEAAIMDYNRDIEEIMKDIRNLEDIRKTLPSGCFNTPSIEKP
Protein: Homer protein homolog 2 (Homer-2) (Cupidin) (VASP/Ena-related gene up-regulated during seizure and LTP 2) (Vesl-2) (Q9QWW1)
Organism: Mus musculus (Mouse)
Function: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2 (By similarity). Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses (By similarity) Required for normal hearing. Negatively regulates T cell activation by inhibiting the calcineurin-NFAT pathway. Acts by competing with calcineurin/PPP3CA for NFAT protein binding, hence preventing NFAT activation by PPP3CA (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9NSB8}. Cell membrane {ECO:0000250|UniProtKB:O88801}. Postsynaptic density. Synapse. Cell projection, stereocilium {ECO:0000269|PubMed:25816005}. Note=Postsynaptic density of neuronal cells. The stabilization and clustering of the metabotropic glutamate receptors appears to be mediated by isoform 1 and isoform 2 at the cell surface.
Interaction partners:
- Metabotropic glutamate receptor 1
- Homer protein homolog 1
- Drebrin
- Metabotropic glutamate receptor 5
Sequence:
MGEQPIFTTRAHVFQIDPSTKKNWVPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINSTITPNMTFTKTSQKFGQWADSRANTVFGLGFSSELQLTKFAEKFQEVREAARLARDKSQEKTETSSNHSQESGCETPSSTQASSVNGTDDEKASHASPADTHLKSENDKLKIALTQSAANVKKWEMELQTLRESNARLTTALQESAASVEQWKRQFSICRDENDRLRSKIEELEEQCSEINREKEKNTQLKRRIEELESEVRDKEMELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKGELKSFLEVLDGKIDDLHDFRRGLSKLGTDN
Protein: Para-nitrophenol 4-monooxygenase (EC 1.14.13.167) (C1I201)
Organism: Pseudomonas sp. (strain WBC-3)
Function: Involved in the degradation of para-nitrophenol (4-NP). Catalyzes oxidation of 4-nitrophenol (4-NP) at position 4 with concomitant removal of the nitro group as nitrite and production of para-benzoquinone.
Interaction partners:
Sequence:
METLDGVVVVGGGPVGLLTALKLGKAGIKVVVLEAEPGVSPSPRAVAYMPPTAAALDRFGLLQDIRKRAVMCPDFAYRHGNGELIAKMDWSVLSQDTQYPYMLLLGQNHVSNVIFQHLRELPNVEIRWNHRVEEVDQDDAYVTIETSSPGGTSRLRARWLAATDGARSTVRQKIGLTFDGITWDERLVATNVFYDFSLHGYSRANFVHDPVDWAVVVQLDKTGLWRVCYGEDASLSDAEVRRRLPERFKRLLPGAPTPDQYRVDHLNPYRVHQRCAAEFRRGRVVLAGDAAHATNPMGGLGLSGGVLDAEHLAEALIAVIKNGASTKTLDEYSIDRRKVFLEFTSPTATANFTWMKESDPAQRIRDDAMFKEAGTDRAVMRQFLLDLEKLNGRRVIEKKLKAA
Protein: Mannose-specific lectin (Agglutinin) (B2KNH9)
Organism: Dendrobium findlayanum (Findlay's orchid)
Function: Mannose-specific lectin. Shows agglutinating activity towards chicken erythrocytes. Has antifungal activity against A.alternata and Collectotrichum species.
Subcellular location: Secreted {ECO:0000250|UniProtKB:P30617}.
Interaction partners:
Sequence:
MAFSISSTMIFLLSLALFSTLVSADNHLLPGERLNPGNFLKQDRYMLIMQEDCNLVLYNLNKPEWATKTANQGSRCFVTLQSDGNFVIYDEHEQEGRNEAIWASKTDGENGNYVIILQKDGNLVLYSKPIFATGTNRFGSTAVVVAKRNRKAHFGVEQNIIEVTTNL
Protein: Glutathione S-transferase (EC 2.5.1.18) (GST class-sigma) (adGST) (P83246)
Organism: Asaphis dichotoma
Function: Has a strong specific activity toward 1-chloro-2,4-dinitrobenzene and ethacrynic acid.
Interaction partners:
Sequence:
PSYKLHYFDLRAAGE
Protein: SH3 domain-containing YSC84-like protein 1 (Q96HL8)
Organism: Homo sapiens (Human)
Interaction partners:
- Actin nucleation-promoting factor WASL
- Mevalonate kinase
- SH3 domain-containing protein 19
- Actin nucleation-promoting factor WAS
Sequence:
MNNPIPSNLKSEAKKAAKILREFTEITSRNGPDKIIPAHVIAKAKGLAILSVIKAGFLVTARGGSGIVVARLPDGKWSAPSAIGIAGLGGGFEIGIEVSDLVIILNYDRAVEAFAKGGNLTLGGNLTVAVGPLGRNLEGNVALRSSAAVFTYCKSRGLFAGVSLEGSCLIERKETNRKFYCQDIRAYDILFGDTPRPAQAEDLYEILDSFTEKYENEGQRINARKAAREQRKSSAKELPPKPLSRPQQSSAPVQLNSGSQSNRNEYKLYPGLSSYHERVGNLNQPIEVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEGKLRGQTGIFPANYVTMN
Protein: Peroxiredoxin PRX1, mitochondrial (Prx) (EC 1.11.1.25) (EC 1.11.1.27) (1-Cys PRX) (Glutaredoxin-dependent peroxiredoxin) (Glutathione-dependent peroxiredoxin) (Mitochondrial thiol peroxidase) (mTPx) (Thioredoxin peroxidase) (P34227)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Involved in mitochondrial protection of cadmium-induced oxidative stress.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:10821871, ECO:0000269|PubMed:14576278}.
Interaction partners:
- Glutathione reductase
- Glutathione S-transferase 1
- Peroxiredoxin AHP1
- Glutathione peroxidase-like peroxiredoxin HYR1
- Thioredoxin-2
- Sulfiredoxin
- Transcriptional regulator URE2
- Glutathione hydrolase proenzyme
- Glutathione peroxidase-like peroxiredoxin 1
- Peroxiredoxin DOT5
Sequence:
MFSRICSAQLKRTAWTLPKQAHLQSQTIKTFATAPILCKQFKQSDQPRLRINSDAPNFDADTTVGKINFYDYLGDSWGVLFSHPADFTPVCTTEVSAFAKLKPEFDKRNVKLIGLSVEDVESHEKWIQDIKEIAKVKNVGFPIIGDTFRNVAFLYDMVDAEGFKNINDGSLKTVRSVFVIDPKKKIRLIFTYPSTVGRNTSEVLRVIDALQLTDKEGVVTPINWQPADDVIIPPSVSNDEAKAKFGQFNEIKPYLRFTKSK
Protein: TANK protein (Q6NW12)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKSQLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQPQDKVISGIAREKLPKVRRQEVSSPRKETSARSLGSPLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATETQCSVPIQCTDKTDKQEALFKPQAKDDINRGAPSITSVTPRGLCRDEEDTSFESLSKFNVKFPPMDNDSTFLHSTPERPGILSPATSEVVCQEKFNMEFRDNPGNFVKTEETLFEIQGIDPIASAIQNLKTTDKTKPSNLVNTCIRTTLDRAACLPPGDHNALYVNSFPLLDPSDAPFPSLDSPGKAIRGPQQPIWKPFPNQDSDSVVLSGTDSELHIPRVCEFCQAVFPPSITSRGDFLRHLNSHFNGET
Protein: Mitochondrial ribosomal protein L2 (C9IY40)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MALCALTRALRSLNLAPPTVAAPAPSLFPAAQMMNNGLLQQPSALMLLPCRPVLTSVALNANFVSWKSRTKYTITPVKMRKSGGRDHTGRIRVHGIGGGHKQRYRMIDFLRFRPEETKSGPFEEKVIQVRYDPCRSADIALVAGGSRKRWIIATENMQAGDTILNSNHIGRMAVAAREGDAHPLGALPVGTLINNVESEPGRGAQYIRAAGAGNVRSNSRPSIQR
Protein: Ornithine decarboxylase antizyme 2 (AZ2) (ODC-Az 2) (Seizure-related protein 15) (O08608)
Organism: Mus musculus (Mouse)
Function: Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimers. Does not target the ODC monomers for degradation, which allows a protein synthesis-independent restoration of ODC activity. Involved in the translocation of AZIN2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol.
Subcellular location: Nucleus {ECO:0000269|PubMed:19725046}.
Interaction partners:
- Antizyme inhibitor 1
- Ornithine decarboxylase
- Antizyme inhibitor 2
- Gene model 853
- Spermidine synthase
- S-adenosylmethionine decarboxylase proenzyme 1
Sequence:
MINTQDSSILPLSKCPQLQCCRHIVPGPLWCSDAPHPLSKIPGGRGGGRDPSLSALIYKDEKLTVTQDLPVNDGKPHIVHFQYEVTEVKVSSWDAVLSSQSLFVEIPDGLLADGSKEGLLALLEFAEEKMKVNYVFICFRKGREDRAPLLKTFSFLGFEIVRPGHPCVPSRPDVMFMVYPLDQNLSDED
Protein: Heat shock 70 kDa protein (P25840)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Interaction partners:
Sequence:
MGKEAPAIGIDLGTTYSCVGVWQNDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPRHTVFDAKRLIGRKFSDPIVQADIKLWPFQVRAGAHDVPEIVVSYKNEEKVFKAEEISSMVLIKMKETAQASLGADREVKKAVVTVPAYFNDSQRQATKDAGMIAGLEVLRIINEPTAAAISYGLDKKDSGLGERNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDERLVNHFANEFQRKYKKDLKTSPRALRRLRTACERAKRTLSSAAQTTIELDSLFEGVDFATSITRARFEELCMDLFRKCMDPVEKCLHDAKMDKMTVHDVVLVGGSTRIPKVQQLLQDFFNGKELNKSINPDEAVAYGAAVQAAILTGEGGEKVQDLLLLDVTPLSLGLETAGGVMTVLIPRNTTIPTKKEQVFSTYSDNQPGVLIQVYEGERARTKDNNLLGKFELTGIPPAPRGVPQINVIFDIDANGILNVSAEDKTTGNKNKITITNDKGRLSKDEIERMVQEAEKYKADDEQLKKVEAKNSLENYAYNMRNTIREDKVASQLSASDKESMEKALTAAMDWLEANQMAEVEEFEHHLKELEGLCNPIITRLYQGGAGAGGMPGGGAGAGAAPSGGSGAGPKIEEVD
Protein: Large ribosomal subunit protein eL32y (60S ribosomal protein L32-2) (Q9FHG2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Large ribosomal subunit protein uL18y
- Large ribosomal subunit protein eL42z/eL42y
- Large ribosomal subunit protein eL38z/eL38y
- Small ribosomal subunit protein uS9x
- Large ribosomal subunit protein uL18z
- Large ribosomal subunit protein eL21x/eL21w
- Large ribosomal subunit protein uL6x
- Large ribosomal subunit protein eL24z
- Large ribosomal subunit protein uL6z/uL6y
- Large ribosomal subunit protein eL29y
Sequence:
MAVPLLTKKVVKKRSAKFIRPQSDRRITVKESWRRPKGIDSRVRRKFKGVTLMPNVGYGSDKKTRHYLPNGFKKFIVHNTSELELLMMHNRTYCAEIAHNISTKKRKAIVERASQLDVVVSNKLGRLRSQEDE
Protein: LP10272p (Tetraspan membrane protein in hair cell stereocilia, isoform A) (Tetraspan membrane protein in hair cell stereocilia, isoform B) (Q9W068)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Cadherin-99C
Sequence:
MGTKIEYVDTTHLYASKYIRNSKAIGVLWAIFTICYAIIGIVAFVTPEWIGDPDNDGAGRLGLWQQCQRDEIFDNCRRRWESIFEVPTFSFQLATFFMLGAIALALLTIFFLVCLLFMKSTRVFHLCGWMQIISAICMIVACAAFPFGWNSDDFRKICGPEANRFELGLCGIRWAYPLAIIGCIDGVVLATLAFILATRHVRLQPDPIYQNSLYKGEINNAYLTDAISLAGSRKSNPRITGLNLQPILLVAPPNEDSISQFSRYH
Protein: Paralemmin-1 (Paralemmin) (Q920Q0)
Organism: Rattus norvegicus (Rat)
Function: Involved in plasma membrane dynamics and cell process formation. Necessary for axonal and dendritic filopodia induction, for dendritic spine maturation and synapse formation in a palmitoylation-dependent manner (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:16847661}; Lipid-anchor {ECO:0000269|PubMed:16847661}; Cytoplasmic side {ECO:0000269|PubMed:16847661}. Cell projection, filopodium membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Cell projection, axon {ECO:0000269|PubMed:16847661}. Cell projection, dendrite {ECO:0000269|PubMed:16847661}. Cell projection, dendritic spine {ECO:0000269|PubMed:16847661}. Basolateral cell membrane {ECO:0000269|PubMed:16847661}; Lipid-anchor {ECO:0000269|PubMed:16847661}. Apicolateral cell membrane {ECO:0000269|PubMed:16847661}; Lipid-anchor {ECO:0000269|PubMed:16847661}. Note=Translocation to the plasma membrane is enhanced upon stimulation of neuronal activity. {ECO:0000250}.
Interaction partners:
Sequence:
MEVLATDTVSQQERLQAIAEKRRKQAEIESKRRQLEDDRRQLQYLKSKALRERWLLEGTPSSASEGDEDMRKQMQEDEQKARSLEESITRLEKEIDVLEFGESAPAAPKENSAAPSPIRPHSTSPAKEEQKSETMVNAQQTPLGTPKENRKSTPVRSPGGSTMMKAAMYSVEITVEKDKVTGETRVLSSTTLLPRDPLPQGVKVYEDETKVVHAVDGLSENGIQPLSSSEVDELIHKADEVTLSEAGSTTGPAEPRGLAEDVTRTTPSRREITGVEAQPGEATSGPPGIQPGQEPPVTMVFMGYQNVEDEAETKKVLGLQDTIKAELVVIEDSVTPREPAPLNGSAAELPATKEENQTGPTTTPSDTQDLDMKKPRCRCCSVM