Protein: Dystrophin-1 (Q9TW65)
Organism: Caenorhabditis elegans
Function: Plays a role in cholinergic transmission and as a functional partner of dystrobrevin (dyb-1), necessary for muscle maintenance. Required for neuronal positioning.
Subcellular location: Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton.
Interaction partners:
- Syntrophin-1
- Dystrobrevin-1
- Dystrophin-like protein 1
- PDZ domain-containing protein
- Alpha-catulin
- Dystroglycan-type cadherin-like domain-containing protein
- Dystroglycan 1
- Sarcoglycan complex subunit protein
- Tropomyosin isoforms a/b/d/f
- Beta-sarcoglycan
Sequence:
MLFSGASTAKPKKDEKKDKKSDRDPKNELQEWVFVRWANHLLGTERLTDYKSLQDGSNAIFVYQAIIGQTMAVLGNPSDDWPNVLQNIGDSKTNPQEVMEGQQKAVLSAWWQLVQFFWKNNAPVQLREEKLSEAIKQWCIEVMKSYEEIDVYDFTSSFRDGHAFNYLIHSYDRKLINLTKTAEMSAIDRIENAFAVAEKTWNVPRLLNPKDLHSDQLDSHSVLCYLMSLYLAMISTSKIETELEAQQIQQQKVAALLASHKMLSSQPSTSSSSALQIPPQTPPTAHHQAMLDRGKSFEQSAEGEVRSRKSSSSSQKSGKSKKARREEQLAEFKSCIEQVLTWLLEAEDELTTLTQMPRVELASVRSQFSDFESFMSSLTDSQDTVGRVLLRGQMLSNKSESEEEKESIGANLHLVNTRWEALREQAMQEQAVLQQQIHLLQQSELDTISQWLDAAELEIESFGPLAADSSQALRQIELHTKFQQKLNDFQETIDKLESFVAVVDEENDASVATLEDALSAVSVRWGHVCEWAEKRATKLDGLADLLDKTNEVFENLSGWLAERENELMTGLKSAHHLENEEQVAQQVRRLQKTEEQLEQEHASFVRLSQLSCELVGRLDDSNGAAANAVRLSLDSITQRWDNLVARIEEHGKTLVKSGKADVKQVQESQNEQKEQPASSEGLSTDTEGEEQKNQLVDKFLLHISKLSHELEPLQDWSEKFEVSRKKDDIRKMMNTCQEKLIQIKEQEARVNRLQLELEHLHVAKLNARQLKRANDAFEQFAKGWARIVTKISEAMNVLTGQEAGGNGNGSEEAAVAAKIEQWIEAVDKVINELSQLPVNERRSRIDKLEQQLQVQDKNVGFIEKDLLKKAILKKGLEIAGKRLAALKVEEKPVEKEEQLVLSNSEEPEAEKHVTFVQETTEKPAPLQEPTSEAQLLEELDGPWSRVGDVVAIEHDLLRAKRAVDTARNSQMSNETVEKAETRKAEMEEKRRVTMSARSKFRMAEETLEEIERNLDRLQVSDLEIADLVRGLEQEAAKLGERVSQRKEAERTAEKILSMDDDEISQEIVIKTKDSTEKLIKRWNQLELDLEENLRKAKRDQDVFIQKRLREGEEALNEIKTAIEGKRESLDAETAAENLDHLESSLDNISSLFGEIGSLPMDDNSREKLSKLAKAKDQITARANEALAALTRTVSECEDFEKQIMLFQNWSARIGFLLQARKSADISAFDIPHEYHEDLGNEAELIPKLSREFEEWTVKLNEMNSTATEKDDSARMREQLNHANETMAELKRKFNEFKRPKGFEEKLEKVITTLSNVEMGLDDTTGIDGSECGGALMEVRALVRMLDGAQEKWKDLAENREQLVKDRVLDEETSKETLQKLQYAKTKSKELYERSSTCIERLEDCVEMYQRLKMESDEIERFLEEMEGKLDQYAASDRPEEAEIVNELISEWNRNEAAMKNAEHLQRQLNERAIKIPDDVLSLKRLRADALKNRLNSWCRTIQEMSEDDESALLEIDELHQNLEKELKLVSDKEPSKIAEKLRFLRADRDRLSSRTRKLAAKNPRLAATSSDVLAGLNQKWKELEVKASAEKAPAPELRDARLSSPSEQPFDKRVQELCDLFENLEAQLDFNGSPVSMVTEYQKRVENLDEYLDEYRPALDDTIEEGRKIAETGRLELQTHSAIEKLDELTNRIEQVEVELDKHRDKVPSLVEQHEQLKKDIDSFLLVLDVFTDRNLDDVDIAKSTRKELAERDSHIVSLTSRATAIHCALPGKGPQLHDVTLDKLRDRIEKLEARLSATEKKPVETVKSTIPDRPEVPEEPEKSSPDRTSRSSLQLAMEAYGTATEDDSVISEAVTVGQKSVDQVDPVEQLEPVEPVEPKLEVKQLKDEATEEEEKRTIILPDETEKVIETIPAARPSAGPSEGTVAEVSTSEILKARPAQESIERTVREVPVDEYEETANISSGDELQDHKISSAVPDSESEIASMFEVLDSIEDSHTNFEEFPFDYLDSADDDLKKTLLKLESCEKTLAKNEMTINIAQAENARERITMLRQMALQRKDKLPKFNEEWNAMQELIQLADALVDEAERYESDQIPQMDRKSAPNVLGELRKRVANAEGPVIDLVKKLSQLVPRMQEDSPKSQDIRQKVYGIEDRFRRVGQAEGAAISKALSSALTEPELKLELDEVVRWCEMAEKEAAQNVNSLDGDGLEKLDGRLAQFTKELQERKDDMVQLEMAKNMIIPSLKGDAHHDLRRNFSDTAKRVAMVRDELSDAHKWVATSRDTCDTFWADIDSLEQLARDVVRRANGIRMAVIYTPSRENVEGVLRDVQRLKMSIGDVKKRVQTANLPPAIKLAGKNAKRVVQVLTETATTIADCHDIPTYLIDEMNDSGGDTTESRSTVVEMTSVHTKQSSSSSSNKTPSAGGESDDAHTLNGDDEQSEEDQKIYSRESSSTLPRGVSSLGSTGSSGVLDPVAVQLTHTRHWLHDVERDASITVDLAQWQPARELWQSIQGIIDEIRLRSVHVTGAHDASPNRQVRQQAAQLLTEMRRTIENCEKRCLILNQISDIARQNEASRNEMELWLKSASDVIGERRVEELSEEVVRQELQVLERVVEQLTERKDKMAEINSQANKIVDTYTKDEAHNLSHLLSRLNMSWTKFNDNIRIRRAVLEASLRSRRDFHSALSEFEKWLSRQEDNCSKLSADTSNHQAIKDTSKRKNWTQSFKTLNAELNAHEDVMKSVEKMGKMLAESLESGNEKVELLKRVGETTRRWTALRKTTNEIGERLEKAEQEWEKLSDGLADLLSWVEAKKQAIMDEQPTGGSLSAVMQQASFVKGLQREIESKTANYKSTVEEAHSFLMQHDLRPKLHSPHVLDDDYEKEELANLEQRRRGLEINANCERLKKNWAELGIEVESWDKLVQHAMQRLQELERNLAECQLHLTSSENEIETMKAVEKIHLEDLKIAREETDQISKRIDEVRLFVDDVNDAAARLLAEDLKLDEHAKGQIEHVNKRYSTLKRAIRIRQAAVRNAASDFGPTSEHFLNQSVTLPWQRAISKSNLLPYYIEQTSEKTQWEHPVWVEIVKELSQFNRVKFLAYRTAMKLRALQKRLCLDLVDLTLLEKAFVRLKGLSAEECPGLEGMVCALLPMYEALHAKYPNQVQSVSLAVDICINFLLNLFDQSRDGIMRVLSFKIAMIVFSNIPLEEKYRYLFKLVSQDGHATQKQIALLLYDLIHIPRLVGESAAFGGTNVEPSVRSCFETVRLAPTISEGAFIDWVKKEPQSIVWLAVMHRLVISESTKHASKCNVCKMFPIIGIRYRCLTCFNCDLCQNCFFSQRTAKSHRTNHPMQEYCEKTTSSDDARDFAKMIRNKFRASKRQKGYLPIDVAEEGIPLTCPPAKVTNQATEQMNADTSQMTAHLAKLSAEHGGGAEHMEPVQSPLQIINQVEQLQRDEMDQMLHRLQFENKQLRKELEWKRGAASTMEIDRSSKRHQERHQSESRGGTLPLRNGRSVVSLKSTQSQNDVMDEAKALRLHKQRLEHRSRILEQQNEQLEMQLQRLKKVIDAQKQQAPLSTNSLLRGSHHQPWSPERARSGSASTLDRGLIVSSRHQEQAEAAGGGAEDSSDEAGGAGGGPRGSSVGQMQNLMTACDDLGKAMESLVVSVVYDSDDEEND