Protein: Polyketide synthase RzxE (Q4KCD4)
Organism: Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- AMP-binding enzyme
- Non-ribosomal peptide synthetase PvdD
- Non-ribosomal peptide synthetase OfaB
- Non-ribosomal peptide synthetase PvdJ
- Non-ribosomal peptide synthetase OfaC
- Non-ribosomal peptide synthetase OfaA
- L-cysteine--[L-cysteinyl-carrier protein] ligase
- L-cysteine--[L-cysteinyl-carrier protein] ligase
- [acyl-carrier-protein] S-malonyltransferase
- Non-ribosomal peptide synthetase PvdL
Sequence:
MDSKIRVLHGKIQRQEISVEQAALEFERLRAQALQEPAPRRIEAPPANAELSAAAVYHYDEPCLRDHQFNHQQILLGLTYASLALEHGLGQLSEGQALQLQRLTFAAPMALAAGEQLEVAIRAGQPGFEAVCRRTPLEPWQVVASGELLAVAASSLPMSSPSVPPAELRAGMTAVELESIYRISEQLHIGQSYRTLQALYMQANGREAVSRVLLKDERHYALHPLLINSAFMTLIPLLAAEQLASHYIPLGIKSLTFHRRQAPASGWIHARLLKNSGELLLFDADLYSDDGALIAQFKGCSIKRLRSAGLVAPEAPHRTGSAAAVEDYLLAQLHGIGASRVGKQQRLRNLMDLGLESVQLVQLAQCIASAAQIELEATVFFEYPSLAELATFLWQEHPTAFIRLLGEQSGATVQVVEEWPAQPVTGPEVISQTQTTPQAGKLPQSDIAIIGLHGQFAEAGDLDQFWGNLWQDLELIKPVPADHWDIEPWFDADPEAQDRTYSRWGSFIADVDKFDAGFFNLSRREAQWMDPQVRLLLQSAYTCAEHAGVIAGLRGSNTGVFIGSCFNEYIDKISELGLPMDPYIATGSGTIAANRISFWFDFKGPSLMFNTACSSSLVALHAACMALRNGECGMALVGGSNLLLSSWHYRYFSAIRALSPTGRCHTFDARADGYVPGECVATLLLKPLAQALADGDPIQGVIKGSAALHGGYTPSLTAPSVAGEENVIVQAWQNAAIDPRTLSYIEAHGTGTRLGDPIEINALKRAFARYTNDRGFCHIGSVKANIGHTEGAAGIAGVLKVLLQMKHKKLPALGHFQQHNPHIKLEDSPLLIDTQGCDWPEQATPRRAGVSSFGFSGTNAHAVLEEYREQRTFATHQGQTVLVPLSARNEQRLQQQVARLLDYLKQHSPDLAALAYTLQTGREAMAARAIFSVDSHERLQQQLQAWIDGQRADPPAVPLMTCAQALAAADLKQLAALWLAGADTENGIDWAQLYGSGRRPARIGLPGYAFAKDRYWLEAPTPSGATATLETSLLTCSEQWQDVEEPCGGAGIKRLICLLAEPGLRRQLADEVQALSPDTELLFVAPGPLNERDQEGHYRVAVHHPHLLQQGLQQVLGSAVATRVLYLWGMDDRRWISDSSPIVALLKAMAVTAAPVARLLLAGRASNGLERCHLESWIGIERSLGSLMACAVEVAIDEAIDVHGAGADERRWLQRLWRQLSGQPTGSRLYRDTRSQRPVLIAAPVEAAAEPLALDQLNTLLITGGLGELGLLLAGELSNRARLRTDGQLQLLLNGRSPLSATTRARIDALSHEHCRVFHVQADCADRPALTAALAPVLAQSGPIDGLIHAAGLQASGSVLASSPEAFAAVLNAKIGATQVLDQVLAEQPLALICHFSSSSALLGDMGACSYAMANRFQQAYARYVQRGRARRVVAINWPLWREGGMALGERESTEFYLKSSGQRMLESAEGLALLRQIVGSDIPQVLVLAGQPARLQQLLEGINQPTAKATAGQPATVLPRAPAHSRPELKGLSLEQSLAWDLRELASRPLQAERQSLEEECNLADFGFDSISLAEYAGLLNRHFGLTLTPEVFFSHSTLAKLAAHLLAQHRQAVEACYLHPVTRDPQAEPEAQPETQPEAQPEAQPAPLTSSASASAPATEAMAIIGISGRFPGARTTDELWQVLAEGRDMVSEIPPERYDWREHYGDPRENPTKTRCIWMGSVPGIDEFDPLFFEISPREATHLDPRQRLLLQESWNVLEDAGIGPRQLATQRVGMFVGVEEGDFQRLAGEESLTSSHNGILASRLAYFLNLTGPTMAINTACSSALVALHQAASSLRNQECEMAIAAGVNLIFSADAFIGMTQAGMLSPDGKCFAFDHRANGMVPGEAVCCVLLKPLARAEADGDRIYGTLRASGLNYDGKTNGITAPSGVSQQRLLEEVYRRAGIDTQAVDYIVTHGTGTQLGDPVEINALNDAFGGNSPGHCALTSTKTNLGHTFAASGLVSVISLLQALRHETIPASLHCEQENHYIQWQQSPFYVNKANKPWPQAGRDRERLGAVSAFGMSGTNAHVVVQSYSQRADDAALRRPCYVLVLSAKTAEALEEKAAQLNVALEQGGYRDAQMPAISHTLLEGRHHFRYRLALVAADLEETRYGLQRYLAGEKRPNLFAGEVERDFAPRKTVVRYIEQLLDDSLTCHDDELRELLSGLADCYRQGYEIDGRRLFAAPPTRVSLPGYPFARERYWPQARPRSAAAAGQAKEHLHPLLQRNVSTLARQCFVSRFSGRERFLADHRMGDQQIFPGAAYLEMAREAIVRASERPMQQVTLRNLVWLRPLAFAQGAGAGEVELFCELTLSSGDSLSFRIYSLDGTVQQLHAQGDALLADVAPPMPAALDLSQLAAECNLGERSHDALYRDFESMDVHYGSSFRAAGQILIGQNRVLGQLSGAALDPQMDGVPLPPGILDSALHIAATLGAGQQAAAAALPFALESLRLYGSLEQSLRLAPLTVIASRRAMPDGAAVDKVDLQICNHAGACLLHLEGFSSRRTSVEAAAVSTLAPRASGEVLGRLIRTPYWQPLDNPGQALPSDARPQLLLLGLPDAVVADVRRQFGPQVSVLPGAPGASGAAHYQTAALALLECLQQRRAGTGDYLQLYVGQGQDDLRLTALDALLSTAMIENCELKARLVAVDPDMGDAAMSQVIARQSRFHCGQRVRVFASGSLYAHQWRELAVQPAHSDEPGAFRDGGVYAITGGGGGLGLVFARQIASSCRNPVLYLAGRSQPSAAAQGMFEQLQALGARVVYRSLDVSDAAAVSQWIDGIYAEQGQLHGLIHSAGVIRDSLIMHKSASDFAQVLAAKVTGIENLDQAIGERPLDFMLCCSSQAAMGNLGQADYASANAWMDAYMHYRQNLAADGKRKGRSLSINWPLWRDGGMGLAPVIEQQLREQLGIVPMPQAEGLDSLHQLLTQSVHPQAWVVYGQLSRLAGIGLTPAVPAQAALEPAPQPASGASQLSDSELRTYIAAFVTRIIAKVTQIDEAKIHPAEKFEVYGFDSIMAVGVTNELEKHLGSLPKTLLFEHVNIAGMVEHFAVKYRQRFAALLADEEQPLPVAGPAAPSAQPLAGKRFAVASSTATSPAPEPVEDSDLSQYVAVIGLGGYYPGADSIDQLWQNLANGVDCMSEFPAERWDHRKLYYKNREVLGKSTCLNGSFIKDVDKFDYSYFKMPKVYADHMSPEVRLFLQTAVHTFEDAGYSRETLQSRYGGNVGVLLGAMSNDYHYYGFEHNLSGGSIASGSGMATIPMTVSYFYGLTGPSLFIDTMCSSSSTCIHSAFQMLRHDETMMVLAGGLNLMYHPYTVVNTSQGNFTSITSQSVNSYGVGADGTVIGEGVGAVLLKRLDRAIADRDQIYGVIKGSAITNAGERNGFNVPNPDLQTLAIRQAMEQAKVHPASISYVEGHGSGTRLGDPIEVLGLKNAFAVDTDEKQFCYLGSIKSNIGHLLAASGVAGLTKTLLQLKHGHIAPSIHSGLLNQDIDFADTPFMVPQQLTQWHRPERMIQGELQRFPRRAGLTSIAAGGMNAHLIVEEYPQPADAAGQIAEEHLAFVFSVHKLSLLVENLSRLRDWLASSDASLAQIAYTLQVGKNNLRNRLVIRCDSRQALLEALTACIDGQYGGDTFYRFQETDAAQLPEGDGPLTSRMKQWLGGDNQVDWASLYQRQPQRISLPAYAFEKNRCWYTEPDYESAIINPLMFTGKLHPLVAENCSTTQPGALFRTDFVPAQLLDYLYQAPGGQRISAFNFADVALAMPALVSRFAGCTLSVSCAFEHFIADWASVSGLAYRLLEIDEGQLELEFDVQRPGQPSLNLGFALINPLTGNEPALAQSLLDAASELLNQTQADGSLSDADISRRLAQAGYDFSPYLDHQGRGAISRSGLLLEGRPPINRHNHHADNLQLSPYLATTLDKALYLLLEELGLPQARVIVRNIEQLCCYEPPAGPFSVVLTQIGLSGDALGFSVLVLDQQARICLKADRVSLHLGEQERAHVHRDHPWLAGALADDAGVPVAPRPQPVATTPPAQDGQAEAASGTRILAFIQHQLQHKLGFAPQEIGESAQVHDLGLDSIMVMQLTDSLNKHFGTRLMPDLFYEKQQLGELAAKLQAVQEPLH