wanglab/gogpt-training-data huggingface dataset:
Protein: Candida glabrata strain CBS138 chromosome A complete sequence (Q6FY19)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- Candida glabrata strain CBS138 chromosome L complete sequence
- Candida glabrata strain CBS138 chromosome B complete sequence
- alpha-1,2-Mannosidase
- Nucleoporin NSP1
Sequence:
MSKWQKRHIVLAVLVLVVFLRVHGNLRGLSGQFRAKYPKNYLVSNGDTSGLNLKQLKFNSNDLRSDLSKAFPYDPSKPIPRRVWQTWKVPIDSPEFPGDLKPYVSRWESNSYEVDEDEIYSQENEQNYYLLPDDQIESILESFYGEVPIIVQAYKLMPSNILKADFLRYLLLYARGGIYSDIDTFPLKDFRDWPSMNQEDMKKLKKAKIIPYKNFDKTMINGMNFIDPGLVVGIEADPDRPDWADWYSRRVQFCQWTIQSKPGHPVLRELILNITATTIYSSAKTPAHLKSLIDNSADEKDFNINYRHRRRFDKEYDHSQKKQRKNVDGTDIMNWTGPGIFSDSILNYLTNIIRKNRNILLLNSNLDSKQKEIPSSAAGSQEEEEEEDLTYSTKKFYNEISTSLLSSAKMPWEFFSLITEPLLVDDIMVLPITSFSPDVMQMQAESSQHELALVKHMFHGSWKEEADGH
Protein: histone acetyltransferase (EC 2.3.1.48) (Q5ACY2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Histone H4
- Histone acetyltransferase
- Chromatin modification-related protein EAF6
- Chromatin modification-related protein EAF3
- Enhancer of polycomb-like protein 1
- RuvB-like helicase 1
- SWR1-complex protein 4
- Histone acetyltransferase GCN5
- NAD-dependent histone deacetylase SIR2
- Actin-related protein 4
Sequence:
MSVTTTTNIIKASPKRKTKTDTKDQDNSYYGQLNKRNINKVTFGKYEFPTWYGNAAYFYPHDLSHSSLGYEYANKVASEGSIARKIHKKDIFDENLHEFWLDHLFVCEYCFKYTSNETILNQHVTACTYNRKRPSKGKLLYHDQANGYIIREVRGFQDPLFCQNLCLFGKLFLDDKSVYYNIDHFDFYIVFGKDDSSYIPMGFFSKEVLSYDNDNNLACICVFPPFQRRHLGSLLIEFSYQLAAVTPGQLKSSGPEFPLSPYGKVTYLRFWSKRLATKIHELQGSFTLSHLSKETGFRKEDILLTLEYMQILVTDDLGNVTLSLERLENWCSQNKVVPGVDINILNSECLIL
Protein: Bromodomain containing 8 (H7C179)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
GKHKLLSTGPTEPWSIREKLCLASSVMRSGDQNWVSVSRAIKPFAEPGRPPDWFSQKHCASQYSELLETTETPKRKRGEKGEVVETVEDVIVRKLTAERVEELKKVIKETQERYRRLKRDAELIQAGHMDSRLDELCNDIATKKKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPTVMVRSPIDSASPGGDYPLGDLTPTTMEEATSGVTPGTLPSTPVTSFPGIPDTLPPGSAPLEAPMTPVTDDSPQKKMLGQKATPPPSPLLSELLKKGSLLPTSPRLVNESEMAVASGHLNSTGVLLEVGGVLPMIHGGEIQQTPNTVAASPAASVSQPDNCVPMEAVGDPHTVTVSMDSSEISMIINSIKEECFRSGVAEAPVGSKAPSIDGKEELDLAEKMDIAVSYTGEELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHPIQQERDKPVPLPAPEMTVKQERLDFEETENKGIHELVDIREPSAEIKVEPAEPEPVISGAEIVAGVVPATSMEPPELRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSPSHGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDASEKDGGTRGRRCAIEADMKMKK
Protein: Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12) (A0A1D8PIP6)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Deubiquitination module subunit
- SGF29 C-terminal domain-containing protein
- Transcription and mRNA export factor SUS1
- SAGA histone acetyltransferase complex subunit
- Histone acetyltransferase GCN5
- Histone acetyltransferase
- Transcription initiation factor TFIID subunit 10
- Histone acetyltransferase
- Protein SPT3
- Transcription initiation factor TFIID subunit 9
Sequence:
MPSDETISKSNGNIHIATNNINGVGPTTTTDQLDISDQSSTLLHNKINFVRELTPRPDNYSSINSCNHIESVLGTKAKNTVFETYRQAVLISQPIINNNNNNNNNNNNNNNNNTNNNNYKSIYKLKKDGSIIPIEKLINSKNLVLKCHQCHLNNFGNSMICLQCPHVGCCFNDYNHSYSHYKSTKHMFSIDSSCGLLYCFKCNDFINHPELEKIRLQIVLGEHDEEKKKKKKKTTTTTTVDDDDDDDDDFIKQNYVDPGQIAIKGLKGFVNLGATCFMSSILQTLIHNPLIKYQFFNNDLHYFNCEKFHNQFINQGNIDENNACITCSIDNIFQSFYTSTTNEGFGMTNLLTTAWYKQKSLAGFEEQDAHEFWQFLLNEFHMDYQRIINNLNSNSNSNSNSNQDNNEKNTHSSNDDSVVNSCGCIMHSTFSFELQSCIKCDSCDSITETVDPMIDLSLEVNFTNLYQSLQSFTRDEKLDDYNCKNCNNSNNNKSTTTTSAIKKLRLKTLPQILSIQLKRFRHDILGSFQATKIQSHINFPLFLNVTEYSVIKDTDYIYQLFAVVCHQGSINTGHYTVFIKNNSNWYKFDDSVVTMVSQDVVINSEAYLLYYIV
Protein: T. brucei spp.-specific protein (Q57WD4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MKCWSPHSVRKNLAKHLRDLKEDSDAPPALRCLAAESSWDSIDAFGDTCNEGSGATWGYSELEFSGGEIDEAIREEVSSRQSSLTPVGTKRELCIGDSAEEVSGFIRTLSSGSPVGRSVKGGGGRKVSCTPKGRFMNHDGARALSVLLPLTGLRHHPTFPVDPSLSCSQVRKSGGNKFKSAPLLLCDNKQRKPISSRQPKGSFRNHRAHLHQPLASLQPESFFASYPCGRLHHLVRNPKVKQFVAYRSGNGNSDVSNFALDATVTRRSRRQRVNEHLFVDGEVKPHPRSRTHSKHLSESLLTPTASAPILELLAPRKTPHRNAGEGVRGGTLSVRSQFDYCFSPGGTSRSSNNNRIIRQGSAEWFERASGGQNSQSNLYWRHATRVRAALTMRGMGDGGDAGAALSQECGSPVSSLWASTTFTIDMRPSLCDAPLDILMTSSATTGSPYTTIG
Protein: Heterogeneous nuclear ribonucleoprotein C (G3V576)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MASNVTNKTDPRSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHKGFAFVQYVNERNARAAVAGEDGRMIAGQVLDINLAAEPKVNRGKAGVKRSAAEMYGSVTEHPSPSPLLSSSFDLDYDFQRDYYDRMYSYPARVPPPPPIARAVVPSKRQRVSGNTSRRGKSGFNSKSGQRGSSKSGKLKGDDLQAIKKELTQIKQKVDSLLENLEKIEKEQSKQAAGVDQG
Protein: Protein FAM83D (Spindle protein CHICA) (Q9H4H8)
Organism: Homo sapiens (Human)
Function: Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC. May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade. May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18445686}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:18445686}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:15561729, ECO:0000269|PubMed:18485706}. Note=Primarily cytoplasmic during interphase, but at prophase, associates with spindle microtubules, with a clear concentration toward the spindle poles. It persists on spindle microtubules through metaphase and anaphase. {ECO:0000269|PubMed:18485706}.
Interaction partners:
- Hyaluronan mediated motility receptor
- Kinesin-like protein KIF20A
- Casein kinase I isoform alpha
- Targeting protein for Xklp2
- Dynein light chain 1, cytoplasmic
- Chromosome-associated kinesin KIF4A
- Aurora kinase A
- Serine/threonine-protein kinase Nek2
- Disks large-associated protein 5
- Cyclin-dependent kinase 1
Sequence:
MALLSEGLDEVPAACLSPCGPPNPTELFSESRRLALEELVAGGPEAFAAFLRRERLARFLNPDEVHAILRAAERPGEEGAAAAAAAEDSFGSSHDCSSGTYFPEQSDLEPPLLELGWPAFYQGAYRGATRVETHFQPRGAGEGGPYGCKDALRQQLRSAREVIAVVMDVFTDIDIFRDLQEICRKQGVAVYILLDQALLSQFLDMCMDLKVHPEQEKLMTVRTITGNIYYARSGTKIIGKVHEKFTLIDGIRVATGSYSFTWTDGKLNSSNLVILSGQVVEHFDLEFRILYAQSKPISPKLLSHFQSSNKFDHLTNRKPQSKELTLGNLLRMRLARLSSTPRKADLDPEMPAEGKAERKPHDCESSTVSEEDYFSSHRDELQSRKAIDAATQTEPGEEMPGLSVSEVGTQTSITTACAGTQTAVITRIASSQTTIWSRSTTTQTDMDENILFPRGTQSTEGSPVSKMSVSRSSSLKSSSSVSSQGSVASSTGSPASIRTTDFHNPGYPKYLGTPHLELYLSDSLRNLNKERQFHFAGIRSRLNHMLAMLSRRTLFTENHLGLHSGNFSRVNLLAVRDVALYPSYQ
Protein: Putative HNH nuclease YajD (EC 3.1.-.-) (P0AAQ2)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Ribosomal silencing factor RsfS
- Protein YchN
Sequence:
MAIIPKNYARLESGYREKALKIYPWVCGRCSREFVYSNLRELTVHHIDHDHTNNPEDGSNWELLCLYCHDHEHSKYTEADQYGTTVIAGEDAQKDVGEAKYNPFADLKAMMNKKK
Protein: Sm protein F (F4JPK5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR006609}.
Interaction partners:
Sequence:
MAFVCMCVLQTIPVNPKPFLNNLTGKTVIVKLKWGMEYKGFLASVDSYMNLQLGNTEEYIDGQLTGNLGEILIRCNNVLYVRGVPEDEELEDADQD
Protein: Synaptotagmin-like protein 2 (Breast cancer-associated antigen SGA-72M) (Exophilin-4) (Q9HCH5)
Organism: Homo sapiens (Human)
Function: Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine (PS) and phosphatidylinositol-4,5-bisphosphate (PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca(2+) while binding to PIP2 is Ca(2+) insensitive.
Subcellular location: [Isoform 1]: Cytoplasm {ECO:0000269|PubMed:18812475}. Cell membrane {ECO:0000269|PubMed:18266782, ECO:0000269|PubMed:18812475}. Note=Recruited on vesicular structures in cytotoxic T-lymphocytes (CTL) by RAB27A. {ECO:0000269|PubMed:18812475}.; SUBCELLULAR LOCATION: [Isoform 4]: Cell membrane {ECO:0000269|PubMed:17182843}. Note=In the pancreatic alpha cells distributed in both peripheral and anterior regions. Localizes on the glucagon granules in the cell periphery. {ECO:0000269|PubMed:17182843}.
Interaction partners:
- Ras-related protein Rab-27A
- Ras-related protein Rab-27B
- Melanophilin
- Unconventional myosin-Va
Sequence:
MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEPEEDAAPASPSSSVVNPASSVIDMSQENTRKPNVSPEKRKNPFNSSKLPEGHSSQQTKNEQSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLPGLSNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIVSPGLTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLESDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPINGLHSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEPEPSQVPGGSSRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK
Protein: Uncharacterized protein (Q387Q1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSLPIMSVVRMAVQELPLLSFAPTSLVSDGCVFLPTLSDCSAFAGCSITSATLQCDGTLLIKVVPAILRLIPLKGISSSHGYSSLAAGGSHSEAVALLKGLPTVRLQAVSPVFPLFTPGGCVEYFSATSQQTTAAVPVLTNTIREHLRRLRAYVPQHLDELVPSAPSKVSSWFVVSYPGADAVPEPCLFVLPDVLVVRTVMSQVGSRKIPPHHKRSVAVMGQSGVAKLLEELKWSGCAVRVVDDANHVCVLPPTLTAASQMKQVTH
Protein: RH40737p (RH63541p) (Q9VZJ8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Uncharacterized protein, isoform B
- Sorbitol dehydrogenase
- Methanethiol oxidase
Sequence:
MSSGPFFVGVDVGTGSARAALVACDGRVLEQAVQTIQTWNPEPGYYNQSSDNIWQSICQVVKKVIGGVDKSKVKGIGFDATCSLVVLGPQGSPLTVSKSGEAEQNIILWMDHRAEQETQEINAFKHSLLKYVGGQVSLEMEVPKLLWLKRNLSQTFGNIWRVFDLPDFLTWRATGVDTRSLCSVVCKWNYDAANGSWNKEFLKQADLEELTQNNFEKLGSDVQPPGRTVGKGLTAKAAGELGLSAGTVVSTSLIDAHAGALGMFGCRSKESKGADDVQGKMALIAGTSTCHMSITRKACFAQGVWGPYQDAIIPGYFLNEGGQSIAGHLLDHVLKSHESYAELKSQLGEDKFIYQHLNKLLPELAAARGLSQVGCLTQDVHVWPDLHGNRSPIADPTLRGVITGLDMTRGTESLAIKYLAFVQALAYGTRHIIENLYQYGRAPFQTLLFCGGLAKNPLYVQCHADICNLPALIPDEQEMVLVGAAALGAAASGHFDSLESASKSMGGTGQLVKPNAETLEFHNRKYKVFLQLLENQRQYRRIMQADTK
Protein: P-loop containing nucleoside triphosphate hydrolases superfamily protein (F4I5Z7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MLSKVSPSGELLNRWRRIEEDEEENDDSDPSAVRRLNQRKEQWFTDAFTLLISLPKDTHIWCGHGDIMGPLIETFYNYFKDDRVDSPLKVLWKRISEEMRLCAQCICQHHQTQEMYEKEYECSSVGPLLVVLRKLDEERVTRHLQEINLKIEKGTYDPDHHHAEVVSVMYEVLMFPFFFDDMSLCTEFEKFIESIDNIHELAFAENQEFPGVYALLFLNRRVRVIGYRLARAMGKLRSATQLERLQPLLKKFIGILEMEGLPSASQEPRPRIYLDRSSIWLGMTSLLEFLEGPAFEEGILEPYPIFVDTVLNHISGDSPEFSLAVNCLKELFKTLGMSLEALRDGEHEKQRRHFLYFLLHQVPVSSNFSLLARRIGHKIALLIVLRGYKMNPPCPPFECAHMWGPSLVSSYKDSSLHISLRQPAIDLVQAILVSDATALLASLLRNNTGKFMGYEIQYDDDDMESEKNDEMTVDIETWLSSSAVEIKGTLGWKVATGSDDGGPGKESKNSVTVSKMCLTLIRTLKRLTTCYLVQIGDECRKQWTWVPEMGETFILSLSDPDDNVRQFGKSMLEHVSNTRGLSCGLKFLCSQTSHLLFVSSGVRHVLQQVHLSSVLQSFQILHHFFFLLFKLLKEEEVAITDVVKSSAGGFLRQPNFNALPVSEGRNPLSSTPELLKFQYLLAEVAWGIIRKCLVEGKTFIHQSLCQMTCVRLLEILPVVLGKLRVSREESCDTRGTLKDASDLKWLPDLIDWGRSQLKVVVAYWKRALVALLDILQGSNSDACSSAVQAIRHVLSSDDVDIEQLAEQISRLVPKANEYQILKPVDVVGKLQDNMMDLTVDETEKESLKNLPSLHKSHQPDINKTLLPIKNISQISSLKKSTSSIDASKLSALVLSERDVTVSSSNIVRDLPTTNAEPSKAAGMSREAEKRQNVEDPVSSGIRPNLKKATDELGPRGTSKEAQKSAISNAKGMDLRKVVNETEVDPLDLALKSLKRQSLPLAKSGPIVPKRQVIQLCAPVNKKSDRWQRQEAGFKRFRPPKLEDWFRKILQMDYYAIVGLASTKKDESQNVGKFREVPVRFGSPEQYIQIFQPLVLEEFKAQLQSSFQEISSLEEIYYGVISVLSIERVDDFHFVRFMQDENDGSNSKSFSENDLVLFTKEHPENSNVGVNMMGKVEGREWDDKKRTSILNVRLYLQNASSRLNQARRNLLERSQWHASRILNITSQIREFQALSCIKDIPVLPLILSPMNDSNYDSEVKRSDLRSLPHSLQQILKSSFNESQLQAISVAIGSSNLMKAFDISLIQGPPGTGKTRTIVAIISGLLASASHKTSDRGNSEPGHSSSTSRQGMNPSVAVARAWQDAALAKQLNDNSETNRKIAEKNGRGRVLICAQSNAAVDELVSRISSLGIYGRDGKMFKPYLVRVGNAKTVHSNSMPFFLDTLVDQRLAEERMRINESKSNKGADSSALLRSNLEKVVDQITHFEAKRANINQESLDAKDKPENEHHNKDDDGKLMSDAELGIRLRRLYEQKRKIYKDLSAVQAQERKANYEMRTLKQKLRKSILKEAQIVVTTLSGCGGDLYSVCAESLAAHKFGSPSEDNLFDAVVIDEAAQALEPATLIPLQLLKSRGTKCIMVGDPKQLPATVLSNVASKFLYECSMFERLQRAGYPILMLTQQYRMHPEICRFPSMHFYDNKLLNGVDMSSKSAPFHENHHLGPYVFYDIVDGQEHRSGDSSSVCNEQEAEAAVQLLRFFKKRYPSEFVAGRIGIITPYKRQLAVLRSRFTGAFGAQVTADMEMNTVDGFQGKEVDILVLSTVRATHSAPDGVNQSRIGFVADVRRMNVALTRAKLSLWVLGNTRTLQRDHNWGALVKDAKEREVIIPVKRPYNYMFGENVMEQNHSENLPKNFPKPDKQHSRRKEQRAETSSDRKLRKTDGDVVPISSKGSESKHTRRNAKEEASSQREKLVASCEKVTSEETLRRSHEKKEKMKGREKSSNPEITDANSSKNENSNEWKKSKKASSKLDSSKRANPTDKIGQQDRQINKGNASNQGGVEDMISKRKQQREAVAAILNSSLIPSHKPKPPKRPLSPGSTAGSHTRPPKAIKESTKNNS
Protein: Guanylate cyclase soluble subunit beta-1 (EC 4.6.1.2) (Guanylate cyclase soluble subunit beta-3) (Soluble guanylate cyclase small subunit) (Q24086)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MYGFVNYALELLVLKHFGEEIWEKIKKKAMVSMEGQFLVRQIYDDEITYNLIGAAVEILNIPADDILELFGKTFFEFCQDSGYDKILQVLGATPRDFLQNLDALHDHLGTLYPGMRAPSFRCTEKDGELLLHYYSERPGLEHIVIGIVKAVASKLHGVEVEIDIVKRKGEPIDEAEKERAIARENQQLLEDAVATTTTGSATVVLAPSSDAERNNNHNGSNGSNNNGMANNGNTVNVNNNNDGQQIASETDPSIALSTCPIAQDSFDCDGDKEQKCLRLLKNKSDDIERYDHVQFLIREINVAAKSQVDAKKDEVPDDMEFLCEAPLISPATFCKVFPFHLMFDRQMKIVQAGKAVSRVIPRVAEENCSLIEVVEAIRPHLQLNFENILSHINTIYVLQTRQGAMSSRHEQRFLRLKGQMMYIPETDRILFQCYPSVMNLDDLTKKGLYISDVPLHDAARDLVLLSEKFEAEYKLTKNLEMLTDKLQQTFRDLESEKQKTDRLLYSVLPKSVANELRHQRPVPPKRYDSVTLMFSGIVGFGQYCAANTDPDGAMKIVKMLNELYTVFDALTDSKRNLNVYKVETVGDKYMAVSGLPDHCEDHAKCMARVALDMMDMAKNVKMGSNPVQITIGIHSGEVVTGVIGNRVPRYCLFGNTVNLTSRTETTGVPGRINVSEETYRLLCMAINQDDSFHLEYRGPVIMKGKPTPMDCWFLTRATSSILGGTSSTGSGGGGGNGSLDSPLLQPATPTAGGPRPFP
Protein: ShKT domain-containing protein (Q9XVB1)
Organism: Caenorhabditis elegans
Interaction partners:
- Nose resistant-to-fluoxetine protein N-terminal domain-containing protein
Sequence:
MICYAVFLIFLAQFANAQDKPCIDDPNVKCEDFKDDCATEKMIPLLKESCPVTCKLCPPTEAPTTLAPCFDDKDTDCASFKQFCSNSKYIPMLKSFCPVTCNMCPGATTVMPTPNPNCQDNGPNCAGWVKNGYCNKCFYKCSEREKYCAKSCGFCTPGTCKDCNSLETLFSFGANKLL
Protein: Uncharacterized protein (Q23482)
Organism: Caenorhabditis elegans
Interaction partners:
- Protein lin-52
- Protein lin-9
- Protein lin-54
- Probable histone-binding protein lin-53
- Transcription factor dpl-1
- Retinoblastoma-like protein homolog lin-35
- E2F/DP family winged-helix DNA-binding domain-containing protein
- Nicalin
- PAT complex subunit CCDC47
- Calcium load-activated calcium channel homolog
Sequence:
MSEIDPLAEFLLPEDGDRNARQNDPLISGGPLPLESPSRKLTSLLSYDPTVPESPDMKFARKRLGNLLTTIKHHPSEIIGVLPEDYTRADEEPGRQGRPPGRPRKMPRHESSTSLMESPRKTMTRDSKIMFELRGKPFEMIAGRFEEEYSLGRAWVKGHMNNEYEPIKAQRTDYAPNLAVDYLACREIHRMPRPDKSIPELPIVPSRIDEFDATVDPRYETDLKNEYIRHWKQVKKGWCAHQRRRTAPHARSIALINKIYQPGESKTVEQALGLI
Protein: Low molecular weight antigen MTB12 (CFP-2) (Low molecular weight protein antigen 2) (P9WIN7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: May play a role in the development of protective immune responses.
Subcellular location: Secreted.
Interaction partners:
Sequence:
MKMVKSIAAGLTAAAAIGAAAAGVTSIMAGGPVVYQMQPVVFGAPLPLDPASAPDVPTAAQLTSLLNSLADPNVSFANKGSLVEGGIGGTEARIADHKLKKAAEHGDLPLSFSVTNIQPAAAGSATADVSVSGPKLSSPVTQNVTFVNQGGWMLSRASAMELLQAAGN
Protein: Etoposide-induced protein 2.4 (EI24) (Q57WB7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MSSGVPVSSQWPPVRGGLIILRAAFSGARQSLDVVKFLSYVGSSAEVSRNLRSCTLVNFLFFFGIWISSIVFSPLWSLAVTLMRGRSTLAGDPDAITNSASLSNVNRVAGGATGVVTILWTCVFYFVWVFPMYGITLLFGIRWYNALYAAANSEKRRRALLMAAARSPGRPVVPVRGAAAGAGPKPTASSLSFSDVVVSLTETLFKVVATSLCTVVMTVVGTILPVPLGACVDVAMRSWLHAFYVFDYRVSSQYVTDRVTQRRNYVGLSSAIEFFEANWAYFLGFGASRCLVTGVLDLTGIVTSWFAKEAAVSVLFGAHVVLSVEAKLPPRAPFSIPMFTPFFILCDKIIRAVVHVAQ
Protein: Cytochrome c oxidase, cbb3-type, CcoO subunit (Q9I3G4)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Cbb3-type cytochrome c oxidase subunit
- cytochrome-c oxidase
- cytochrome-c oxidase
- cytochrome-c oxidase
- Cbb3-type cytochrome c oxidase subunit
- cytochrome-c oxidase
- Cytochrome c oxidase, cbb3-type, CcoQ subunit
- Probable ferredoxin
- Cytochrome c oxidase, cbb3-type, CcoO subunit
- Probable iron-sulfur protein
Sequence:
MKNHEILEKNVGLLAIFMVIAVSIGGLTQIVPLFFQDVTNTPVEGMKPRTALELEGRDIYIREGCVGCHSQMVRPFRAETERYGHYSVAGESVWDHPFLWGSKRTGPDLARVGGRYSDDWHRAHLYNPRNVVPESKMPAYPWLVENKLDGKDTATKMEVLRKLGVPYTDEDIAGAREAVKGKTEMDALVAFLQGLGTSIKSKR
Protein: Dipeptidyl peptidase 3 (EC 3.4.14.4) (Dipeptidyl aminopeptidase III) (Dipeptidyl peptidase III) (G3V180)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MGEPEAGSEFANGAAAAAGPMADTQYILPNDIGVSSLDCREAFRLLSPTERLYAYHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKEKLERVILGSEAAQQHPEEVRGLWQTCGELMFSLEPRLRHLGLGKEGITTYFSGNCTMEDAKLAQDFLDSQNLSAYNTRLFKEVDGEGKPYYEVRLASVLGSEPSLDSEVTSKLKSYEFRGSPFQVTRGDYAPILQKVVEQLEKAKAYAANSHQGQMLAQYIESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAVVNKAMSAKFERLVASAEQLLKELPWPPTFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAYATQREKLTFLEEDDKDLYILWKGPSFDVQVGLHELLGHGSGKLFVQDEKGAFNFDQETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLHPQVLEIFGFEGADAEDVIYVNWLNMVRAGLLALEFYTPEAFNWRQAHMQARFVILRVLLEAGEGLVTITPTTGSDGRPDARVRLDRSKIRSVGKPALERFLRRLQVLKSTGDVAGGRALYEGYATVTDAPPECFLTLRDTVLLRKESRKLIVQPNTRLEGSDVQLLEYEASAAGLIRSFSERFPEDGPELEEILTQLATADARFWKGPSEAPSGQA
Protein: Actin-related protein 2-B (Actin-like protein 2-B) (Q56A35)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (By similarity). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (By similarity). Seems to contact the pointed end of the daughter actin filament (By similarity). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (By similarity). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q7ZTP2}. Cell projection {ECO:0000250|UniProtKB:Q7ZTP2}. Nucleus {ECO:0000250|UniProtKB:Q7ZTP2}.
Interaction partners:
- WASP actin nucleation-promoting factor b.
- Actin nucleation-promoting factor WAS
- Arp2/3 complex 34 kDa subunit
- Actin-related protein 2/3 complex subunit 3
- Actin-related protein 3B
- Actin-related protein 3
- Hematopoietic cell-specific Lyn substrate 1
- Actin-related protein 2/3 complex subunit
- Actin, cytoplasmic 2
- Actin, cytoplasmic 1
Sequence:
MDSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIIRSTAKVGNIEIKDLMVGDEASELRSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNINSRDCKILLTEPPMNPTKNREKIIEVMFETYQFTGVYIAIQAVLTLYAQGLLTGVVVDSGDGVTHICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVRMMKENLCYVGYNIEQEQKLALETTVLVESYTLPDGRVIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQAADIDTRAEFYKHIVLSGGSTMYPGLPSRLERELKQLYLERVLKGDVDKLSKFKIRIEDPPRRKHMVFLGGAVLADIMKDKDNFWLTREEYQEKGVRVLEKLGVTVR
Protein: Zinc cluster transcription factor CZF1 (Q5A0W9)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Transcriptional regulator of the switch between 2 heritable states, the white and opaque states. These 2 cell types differ in many characteristics, including cell structure, mating competence, and virulence. Each state is heritable for many generations, and switching between states occurs stochastically, at low frequency. Contributes to formation of the opaque state, but is not necessary for heritability of the opaque state. Plays a role in cell adhesion and pseudohyphal growth. Involved in acquisition of drug resistance and acts as a repressor of beta-glucan synthesis, thus negatively regulating cell wall integrity. Plays a role in adherence, invasion and damage to oral epithelial cells.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
Interaction partners:
- Nucleoporin NSP1
- Enhanced filamentous growth protein 1
- White-opaque regulator 1
- White-opaque regulator 3
- Wor4p
- Nucleoporin
- GTP-binding nuclear protein
- Transcriptional regulator of filamentous growth FLO8
- Transcriptional repressor TUP1
- Pre-mRNA-processing factor 17
Sequence:
MSSIPNINWNDPNNGKSNTSRQSQPQPQLPSNVSPPNSRAVPTSGSIGGPQYGSSQFSNEYSRNPNTIGGPPFPLQSNQRGYMPNTGYPVQQTAQQRSGDKLQQVHSQQQQQQQQPLYQQYPPQSVGYLAGDVYNPQHQEYVQMNQLPNQHYNLQQRQQAQGQQLKSQLNEQNAMMSASTQQYPVQDFTNPYPNAQNPAEQQQQQQPLRTQSQQWDGYQSQPLYSAAGNTIPSSIQQQIPPQNLSPSEQQQVKQQQPSPPEQGTKKKPGRKPKLRKLSESSSETPQVPKTASSSSSSPTAVNSGKPITKRSRMGCLTCRQRKKRCCETRPRCTECTRLRLNCTWPKPGTEHKNKPKDQKDDENTIEHAEFGRIKVLRGIVEYRSK
Protein: Reticulophagy regulator 3 (Q9CQV4)
Organism: Mus musculus (Mouse)
Function: Endoplasmic reticulum (ER)-anchored autophagy regulator which exists in an inactive state under basal conditions but is activated following cellular stress. When activated, induces ER fragmentation and mediates ER delivery into lysosomes through sequestration into autophagosomes via interaction with ATG8 family proteins. Promotes ER membrane curvature and ER tubulation required for subsequent ER fragmentation and engulfment into autophagosomes (By similarity). Required for collagen quality control in a LIR motif-dependent manner. Mediates NRF1-enhanced neurite outgrowth (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q86VR2}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes preferentially to endoplasmic reticulum tubules and sheet edges. {ECO:0000250|UniProtKB:Q86VR2}.
Interaction partners:
- 60S ribosomal export protein NMD3
- Gamma-aminobutyric acid receptor-associated protein
- Proliferation-associated protein 2G4
- Eukaryotic translation initiation factor 6
Sequence:
MEEAEGVAAAPGPASGLAFRGRRAMSGSWERDQQVEAAQRTLVEVLGPYEPLLSRVQAALVWERPARSALWCLGLNAAFWFFALTSLRFVFLLAFSLMIIVCIDQWKNKIWPEINVPRPDALDNESWGFVHPRLLSVPELCHHVAEVWVSGTIFIRNLLLFKKQNPGKFCLLSCGVLTFLAMLGRYIPGLLLSYLMLVIIMMWPLAVYHRLWDRAYVRLKPVLQRLDFSVRGYMMSKQRERQLRRRALHSERATDSHSDSEEELAAFCPQLDDSTVARELAITDSEHSDAEVSCTENGTFNLSRGQTPLTEGSEDLDGHSDPEESFARDLPDFPSINVDPAGLDDEDDTSIGMPSLMYRSPPGAGDTQVLPASRNEAALPELLLSSLPGGSNLTSNLASLVSQGMIQLALSEASQTDPSGPPPRRATRGFLRAPSSDLDTDAEGDDFELLDQSELNQLDPASSRSH