wanglab/gogpt-training-data huggingface dataset:
Protein: Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) (P36421)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalyzes the attachment of L-tyrosine to tRNA(Tyr) in a two-step reaction: L-tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). The specificity determinants on tRNA(Tyr) are the base pair C1-G72, the discriminator residue A73, and the three anticodon bases G34, U35 and A36. Also involved in nuclear tRNA export. Also attaches D-Tyr to tRNA(Tyr), this reaction is about 150-fold less efficient than attachment of L-Tyr.
Subcellular location: Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, only a small fraction (about 1.5%) found in the nucleus.
Interaction partners:
- U3 small nucleolar RNA-associated protein 8
- Tryptophan--tRNA ligase, cytoplasmic
- Methionine--tRNA ligase, mitochondrial
- Leucine--tRNA ligase, cytoplasmic
- tRNA-aminoacylation cofactor ARC1
- Isoleucine--tRNA ligase, cytoplasmic
- Tryptophan--tRNA ligase, mitochondrial
- Leucine--tRNA ligase, mitochondrial
- Putative proline--tRNA ligase YHR020W
- Cysteine--tRNA ligase
Sequence:
MSSAATVDPNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPMTKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLLEEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEFQEASEKGYPVATPQKSKKAKKPKNKGTKYPGATKTNEIATKLEETKL
Protein: Large ribosomal subunit protein uL22 (60S ribosomal protein L17) (Q54NG2)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Small ribosomal subunit protein eS7
- Large ribosomal subunit protein eL15
- Small ribosomal subunit protein eS26
- Small ribosomal subunit protein eS10
- Small ribosomal subunit protein eS4
- Small ribosomal subunit protein eS24
- Large ribosomal subunit protein eL27
- Small ribosomal subunit protein uS13
- Large ribosomal subunit protein eL38
- Large ribosomal subunit protein eL43
Sequence:
MTKPVYSKTPSNPEKSCKSRGSNLRIHFKNTRESAMAIKGMLLTRAKAYLNNVLAHRECIPFRRFKGGVGRTGQAKIFGTSQGRWPKKSVEHILSLLQNAEANAEAKGLNVEKLKIAHVQVQRAQQQRRRTYRAHGRINPYMCSPSTVEFILTEVEKAVPKPAEESAQKKKSVATQEISA
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q5B1Q1)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Cell morphogenesis protein
- Tyrosine-protein phosphatase cdcA
- Cell wall biogenesis protein phosphatase Ssd1, putative
- C2H2 transcription factor
- Protein kinase regulator
- non-specific serine/threonine protein kinase
Sequence:
MDAQNGVYGQGYFMPNNYPAQAAYAQPHYGQPNLQSPQPAYQSRMGYNVSPNDGTNGLIQQFSNQDLNSNRTGFFNRSASPAQRPRTAGNTAPGQQQQPGHLAPPVPRSPRLPPENEELQRYPERFSENVHKRGKAAKELVNVFFHENIERARDRNMRSAELDKMMRDPNISQDAKVKEAEMVGKKESTFLRFLRTPETPANFQTIKIIGKGAFGEVKLVQRKSDNKIYALKSLIKSEMFKKDQLAHVRAERDILADSKDNPWLVKLHASFQDPAYLYLLMEFLPGGDLMTMLIKYEIFSEDITRFYMAEIVMAIEAVHKLGFLHRDIKPDNILLDRGGHVKLTDFGLSTGGKKTHDNSYYQNLLKNSTSKDKNRNSGYFNDAINLTVSNRGQINTWRKSRRAMAYSTVGTPDYIAPEIFNGQGYTYLCDWWSVGAIMFECLVGWPPFCAEDTTDTYRKIVNWRECLYFPEELTLSRESEGLIRSFLCDAEHRIGNEGGQYGGATQIKNHPFFRGVVWDQLRKIRAPFEPRLTSNIDVSYFPIDEIPQEDTSAIHRAQARAMPDEQNAEMSLPFIGYTYKAFNAFQAS
Protein: Ligand-dependent nuclear receptor-interacting factor 1 (Q8CDD9)
Organism: Mus musculus (Mouse)
Function: Together with SMCHD1, involved in chromosome X inactivation in females by promoting the compaction of heterochromatin. Also able to repress the ligand-induced transcriptional activity of retinoic acid receptor alpha (RARA), possibly through direct recruitment of histone deacetylases.
Subcellular location: Chromosome {ECO:0000269|PubMed:26391951}. Nucleus matrix {ECO:0000250|UniProtKB:Q5T3J3}. Note=Localizes to Barr body; recruited by SMCHD1. {ECO:0000250|UniProtKB:Q5T3J3}.
Interaction partners:
- Structural maintenance of chromosomes flexible hinge domain-containing protein 1
Sequence:
MSNSLQSVILKTAEEKSGSRCISGCMYQVVPTIGSDGKKLLQLLPISKSSGNLIPVVQSPVMSHGLKANTEKPVQVTFQTQISSSSTSASVQLPVFQPANTTKCFFTGAIDTTGKDRVTSVRTGNFTPPVSNIQNHGVKIHKLTRQTFTIPPSTQNDSSHFIFNTPSLLPNVNSSILPSGNHLKIPAHAEVKSVLASSLPPLVQQKILGTATTSTSGTVEASQIPTVVYVHPVNSVKFVVTKKTQTIYPKPVTFNTLQIPPNVATETQLKGGQHPQAAPVNSIFQEYLQPGIPCIIPVKSSNNVATKVLNTFVGRKNLGDNTIDTPLLNTNSSGRTHSVSEPIKDNALIMFNGKVWLNEKGTCGLPSKIDQQNSVSSDIPLKDSSQLVSSSIVTEISREILNSVLVKSKSFQLKTKSLSNSQLASMANLRAEKNEKVERPSFSVTNPHTMNQSTHCLKQSKTVFINPVFPDGFRTGQNAPRKGNLVQNIEKICSSVDAATVTSQQCVFRDQESQTQYEMASIVKKEIQEKGNNKKYSQGSHTNIKASCLKNDAEFKKLFGLTKDLRVCLTRIPDHLSSGKSFNSFNSLMKSSSYKDANIVVKKEEKKQSFSKKRKAETMKMGNTKKIKIENADDTVMSIMNGTDVASSQPLSSILPTSDISQHNIVTSHSTTREDKRTEAEHCSHEKQEKGTLSSSTSFEQSTFLNKNFMEDIFPVTPPELEETIRDEKIRRLKQILREKEAALEELRKKMYQKQ
Protein: Flagellar biosynthesis protein FlhA (P35620)
Organism: Bacillus subtilis (strain 168)
Function: Involved in the export of flagellum proteins.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Flagellar biosynthesis protein FlhF
- Flagellar secretion chaperone FliS
- Flagellar biosynthetic protein FliP
- Flagellar biosynthetic protein FliQ
- Flagellar M-ring protein
- Flagellar biosynthetic protein FlhB
- Flagellar biosynthetic protein FliR
- Flagellar motor switch protein FliM
- Flagellar motor switch protein FliG
- Flagellum-specific ATP synthase
Sequence:
MSTRDLSVLISVVLIVAMLVIPFPPWLLSILIIINISLALIVLLTTMNMQEALQFSIFPSLLLLLTLFRLGLNVSTTRSILSHGEGGKVVETFGNFVVGGNVLVGLVVFIILIIIQFIVITKGAERVSEVAARFTLDAMPGKQMSIDADLNAGMITEQEAKHRREKVAREADFYGAMDGASKFVKGDAIAGIIIVMINIIFGIVIGMLQQGMSIQEAASHFTMLTVGDGIVSQIPALLISTATGIVVTRAASEGNLGHDITGQLFAYPKLLYVAAATIMLLGIFTPIGILLTGPLAGLLAFGAYTLSKSGKEKEEVDEILEEEAEVDELKSPESVVQLLHIDPIEFEFGYGLIPLADANQGGDLLDRIVMIRRQLALELGLVIPVVRIRDNIALQPNEYRLKIKGNEVAKGELLLDHYLAMSPTPEDDLIEGIETVEPSFGLPAKWISEAVKDEADMLGYTVVDPASVVSTHITEKIKQHAHELIGRQETKQLIDHLKESYPVLVEEVTPNPLSVGDIQKVLAKLLKEKVSIRNLVTIFETLADYGKLTTDSDLLTEYTRQALAKQITAQFAKENEVLKVVTCSGRVEKAIADGVQQTEHGNYLSLEPDISESIVRSVAKEAEQLSLRQETAILLCSPPVRMYVKQLLERYFPDLPVLSYNELEANVEVQSIGVVDI
Protein: Probable outer membrane usher protein ElfC (P75857)
Organism: Escherichia coli (strain K12)
Function: Part of the elfADCG-ycbUVF fimbrial operon, which promotes adhesion of bacteria to different abiotic surfaces. Could be involved in the export and assembly of the ElfA fimbrial subunits across the outer membrane.
Subcellular location: Cell outer membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Probable fimbrial chaperone protein ElfD
- Uncharacterized fimbrial chaperone YcbF
- Uncharacterized fimbrial-like protein YcbU
- Probable fimbrial chaperone YraI
- Chaperone protein FimC
- Probable fimbrial chaperone SfmC
- Uncharacterized fimbrial-like protein ElfG
- Probable fimbrial chaperone YfcS
- Probable fimbrial chaperone YadV
- Uncharacterized fimbrial chaperone YqiH
Sequence:
MYRTHRQHSLLSSGGVPSFIGGLVVFVSAAFNAQAETWFDPAFFKDDPSMVADLSRFEKGQKITPGVYRVDIVLNQTIVDTRNVNFVEITPEKGIAACLTTESLDAMGVNTDAFPAFKQLDKQACVPLAEIIPDASVTFNVNKLRLEISVPQIAIKSNARGYVPPERWDEGINALLLGYSFSGANSIHSSADSDSGDSYFLNLNSGVNLGPWRLRNNSTWSRSSGQTAEWKNLSSYLQRAVIPLKGELTVGDDYTAGDFFDSVSFRGVQLASDDNMLPDSLKGFAPVVRGIAKSNAQITIKQNGYTIYQTYVSPGAFEISDLYSTSSSGDLLVEIKEADGSVNSYSVPFSSVPLLQRQGRIKYAVTLAKYRTNSNEQQESKFAQATLQWGGPWGTTWYGGGQYAEYYRAAMFGLGFNLGDFGAISFDATQAKSTLADQSEHKGQSYRFLYAKTLNHLGTNFQLMGYRYSTSGFYTLSDTMYKHMDGYEFNDGDDEDTPMWSRYYNLFYTKRGKLQVNISQQLGEYGSFYLSGSQQTYWHTDQQDRLLQFGYNTQIKDLSLGISWNYSKSRGQPDADQVFALNFSLPLNLLLPRSNDSYTRKKNYAWMTSNTSIDNEGHTTQNLGLTETLLDDGNLSYSVQQGYNSEGKTANGSASMDYKGAFADARVGYNYSDNGSQQQLNYALSGSLVAHSQGITLGQSLGETNVLIAAPGAENTRVANSTGLKTDWRGYTVVPYATSYRENRIALDAASLKRNVDLENAVVNVVPTKGALVLAEFNAHAGARVLMKTSKQGIPLRFGAIATLDGVQANSGIIDDDGSLYMAGLPAKGTISVRWGEAPDQICHINYELTEQQINSAITRMDAICR
Protein: DnaJ homolog subfamily B member 13 (Testis and spermatogenesis cell-related protein 6) (Testis spermatocyte apoptosis-related gene 6 protein) (Testis spermatogenesis apoptosis-related gene 3 protein) (Testis spermatogenesis apoptosis-related gene 6 protein) (Q80Y75)
Organism: Mus musculus (Mouse)
Function: Plays a role in the formation of the central complex of ciliary and flagellar axonemes.
Subcellular location: Cell projection, cilium, flagellum {ECO:0000269|PubMed:29298896}. Cell projection, cilium {ECO:0000269|PubMed:19919626}. Note=Localizes both to epithelial motile cilium and the sperm flagellum (By similarity). In spermatids, rapidly enriched in the coupling apparatus with the elongation of the spermatid. Tightly attached to the implantation fossa during the maturation of the spermatid. In mature spermatzoa evenly distributed along the flagellum at the radial spoke of the axoneme (PubMed:19919626, PubMed:29298896). {ECO:0000250|UniProtKB:P59910, ECO:0000269|PubMed:19919626, ECO:0000269|PubMed:29298896}.
Interaction partners:
Sequence:
MGLDYYAVLQVTRNSEDAQIKKAYRKLALKNHPLKSSEPGAPEIFKQIAEAYDVLSDPVKRGIYDKFGEEGLKGGIPLEFGSQTPWTTGYVFHGNPDKVFHEFFGGDNPFSEFFDAEGNDIDLNFGGLWGRGVQKQDPPIERDLYLSLEDLFFGCTKKIKISRRVLNEDRYSSTIKDKILTIDVRPGWRQGTRITFEKEGDQGPNIIPADIIFIVKEKLHPRFRREHDNLFFVYPIPLGKALTCCTVEVKTLDDRLLNIPINDIVHPKYFKIVPGEGMPLPENPSKKGDLFIFFDIQFPTRLTPQKKQMLRQALLT
Protein: Phosphatidate cytidylyltransferase (EC 2.7.7.41) (Q7SXP9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MAELRQRGATDKELKHQHSEDKGSETEGKERDGASDSETKPEVPVSADDTPEVLNKALSGLSSRWKNWWVRGILTLAMISFFFFIIYLGPMVLMMIVLCVQIKCFQEIITIGYSVYHSYDLPWFRTLSWYFLLCVNYFFYGETVTDYFFTLVQREEPLRILSKYHRFISFALYLTGFCMFVLSLVKKHYRLQFYMFGWTHVTLLIVVTQSHLIIHNLFEGMIWFIVPISCVICNDIMAYMFGFFFGRTPLIKLSPKKTWEGFIGGFFSTIVFGILLSYVMAGYSYFVCPVEFNNDSNRFTVDCQPSELFQLQDYSLPSVLQSITGWTTVKLYPFQIHSIALSSFASIMGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVNVYIASFIRGPNPSKVIQQLLALRPDQQLHIFNSLKAHLTEKGLLPALEEAA
Protein: Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM-protein 1) (SLIM) (SLIM-1) (Q13642)
Organism: Homo sapiens (Human)
Function: May have an involvement in muscle development or hypertrophy.
Subcellular location: [Isoform 1]: Cytoplasm.; SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm. Nucleus.; SUBCELLULAR LOCATION: [Isoform 2]: Nucleus. Cytoplasm, cytosol. Note=Predominantly nuclear in myoblasts but is cytosolic in differentiated myotubes.
Interaction partners:
- Recombining binding protein suppressor of hairless
- Signal transducer and activator of transcription 5B
- Signal transducer and activator of transcription 2
- Signal transducer and activator of transcription 6
- Signal transducer and activator of transcription 4
- Signal transducer and activator of transcription 3
- Signal transducer and activator of transcription 5A
- Signal transducer and activator of transcription 1-alpha/beta
- Inositol polyphosphate-5-phosphatase A
- Titin
Sequence:
MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVSHPVSKARKPPVCHGKRLPLTLFPSANLRGRHPGGERTCPSWVVVLYRKNRSLAAPRGPGLVKAPVWWPMKDNPGTTTASTAKNAP
Protein: Beta-mannosidase (EC 3.2.1.25) (Lysosomal beta A mannosidase) (Mannanase) (Mannase) (Q8K2I4)
Organism: Mus musculus (Mouse)
Function: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
Subcellular location: Lysosome {ECO:0000305|PubMed:16377659}.
Interaction partners:
- Alpha-mannosidase 2C1
- Lysosomal alpha-mannosidase
Sequence:
MHLHLLLILALFRAGCVVAGPSYSLSGSWRVSNGNGSLELPATVPGYVHSALHQHGLIQDPYYRFNDLNYRWISLDNWTYSTEFKIPFNLSEWQKVKLIFDGVDTVAEILFNNVTIGKTDNMFTGYSFDITNVVKDVNSLKLQFRSAVQYAECQSKAHTSYRVPPECPPVEQKGECHVNFIRKAQCSFSWDWGPSFPSQGIWKDVRIEAYNIAHLDYLTFLPVYDNASQAWNIEIKASFDVASSKSVGGQVTVAIPQLKTQQTNDIELQQEQRIVKLLVKIRKDVAVETWWPRGHGNQTGYNMTILFALDGGLKIEKAAKVYFRTVQLIEEGIKGSPGLSFYFKINGLPIFLKGSNWIPADSFQDKVTSDRLQLLFQSVVDANMNTLRVWGGGIYEQDEFYALCDELGIMVWQDFMFASALYPTEPGFLASVRKEVTYQVRRLKSHPSIIIWSGNNENEVALSVNWFHVNPRDMKTYIDDYVTLYVKNIRKIVLSEDKSRPFIASSPTNGMKTMEEGWISYDPYSIQYGDIHFYNYADDCWNWKIFPKARLVSEYGYQSWPSFSTLEKVSSQEDWAYNSRFSLHRQHHEDGNHQMLHQVKMHFKLPQGTDPLRTFKDTIYLTQVMQAQCIKTETEFYLRSRSEIVDGKGHTMGALYWQLNDIWQAPSWASLEYGGKWKMLHYFARRFFAPLLPVGFEDEGVFYVYGVSDLHKDHHTQLTVRLHHWSSPKPLCSLVNSSIVVKAGEAVVLFQMPVSELLKRCRGCTRETCVVSFYFSTDKELFSPTNYHFLSSLKDAKGLLEANITVNISQKGNVFVFDLETSAVAPFVWLDVGSIPGRFSDNGFLMIRKKLSVLFYPWKPTSKSELQQAFSVTSLTDTY
Protein: LD04071p (Rho GTPase activating protein at 71E, isoform A) (Q9VUR5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSSWAERVHRRAADLGNVVTSCGHPATAPAYPYRLEKVKFGVPLEEVCKHNNNIPGPLLVLILKLNKESPNRRDVFRAPGHQGAMKKLIHFLQAGRLVNVDNYSVFTIASVLKKFLRKIPNGIFGRSGEMELFAINDLQNEAEQTERLHRLFGSLPKYTQHLLVLLFGTFRVIASNAAHASTGMTSEALGVSVAPSFFQSCVSDGKTARMEDVLKFKVSTKIMQNIIDKFATHDIFGRDNYEYYARVTGRILKVQDEWICSFQYPPPPRGKLAQQKYALQHSLEAEKTWLQCQCERWGLLAQEESRSTPALLTSSSSALENSVLSLGVSPEHSFIESCARLSVSLEGPGIYAMTSSPLPAKRNGNGNGNATDYDYDDYADDDEDNDELDGVHDFGAELEISSIAPPQGSRGIYRHKQRAQQQPHHYQQQQQQQQVPPQHQRDYDEDDDDDEDEMTFIKRRYRQNKKKPAPPSSSHHQRRLRTGTKSLDGGGERRTGSGAAGGSGGGASGSAVGNPTPPKLKQRTCSRCNRGIRHSSSCSSNSAGATGSNSGGGGNGGSGAGNGGGAEGGMTMEELRAVNRYAESTKSLSYLPQVRDDFLLGSRISV
Protein: Ent-copalyl diphosphate synthase 3 (IeCPS3) (EC 5.5.1.13) (A0A3G1QTU5)
Organism: Isodon eriocalyx (Plectranthus eriocalyx)
Function: Involved in the biosynthesis of ent-kaurene diterpenoids natural products such as oridonin, miltiradiene, eriocalyxin B and nezukol, known to exhibit antitumor, anti-inflammatory and antibacterial activities, and in the production of gibberellins phytohormones. Catalyzes the conversion of (2E,6E,10E)-geranylgeranyl diphosphate (GGPP) to ent-copalyl diphosphate (ent-CPP).
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
Sequence:
FRSTAAGRCLPVTCCVFPRHFRVSSSSILPSNAKVVGGCKKNRQIAVEAAQSLEVDSQQPMNQEEVSEKMRQLREKIRWMLQNMDDGEISVSPYDTAWVAMVEDIGGGGGPQFPTSLEWISNNQLDDGSWGDLRFLIYDRILNTLACVAVLTQWKMHLHKCQKGLRFIRENIDNLENGNDEMMPVGFEVAFPSLIQTAKKVGIKIPTDSPFMKNIYAKRDLKLRKIPMDILHTKPTTLLHSLEGMEGLDWEKLLNLRTDDGSFLMSPSSTAYVFRHTKDELCHQYLLKSVNKFNGGVPNVYPVDMFEHLWCVDRLQRLGISRYFQVEIQECLDYVYKYWTNKGICWARNTNVQDVDDTAMGFRLLRLHGYDVSTDAFKQFEKAGEFCSFPGQSTDALTGMYNLYRASQTMFNGEHILADAKEYSTNFLHKKRLANAIVDKWIITKDLPGEVGYALDVPFYASLPRLEARFFLEQYGGDDDVWIGKTLYRMLYVNCDTHLELAKLDYEKCQAVHQLEWESIQKWYRDWNLVEFGLSERSLLLAYYIAASTVFEPERSRERLAWAITAILVKTIASQRQLPLETKGESLGSILENEDGGRLIEFLINTIHQLSSEIVVAEGRDITQQLSNTWQKWLKTCKEGGDDDLGEAEARLIVHTLHLSSGLDESSFSHPKYHQLLEATSKVCGQLRLFQSRKQVDVDLATGTTFQIEAGMQELVKLVFTNSSEDLDSLTKQSFFSIARSFYYTAYCDEGAINSHIDKVLFEKID
Protein: Mitochondrial import receptor subunit tom40 (Protein MOM38) (Translocase of outer membrane 40 kDa subunit) (P24391)
Organism: Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Function: Channel-forming protein essential for import of protein precursors into mitochondria.
Subcellular location: Mitochondrion outer membrane; Multi-pass membrane protein.
Interaction partners:
- TOM7
- Mitochondrial import receptor subunit tom20
- Mitochondrial import receptor subunit tom22
- Mitochondrial import receptor subunit tom70
- Mitochondrial outer membrane beta-barrel protein Tob55
- Mitochondrial outer membrane protein porin
- Topogenesis of outer membrane beta barrel protein 37
- Mitochondrial distribution and morphology protein 10
- Mitochondrial outer membrane protein
- Mitochondrial import inner membrane translocase subunit tim50
Sequence:
MASFSTESPLAMLRDNAIYSSLSDAFNAFQERRKQFGLSNPGTIETIAREVQRDTLLTNYMFSGLRADVTKAFSLAPLFQVSHQFAMGERLNPYAFAALYGTNQIFAQGNLDNEGALSTRFNYRWGDRTITKTQFSIGGGQDMAQFEHEHLGDDFSASLKAINPSFLDGGLTGIFVGDYLQAVTPRLGLGLQAVWQRQGLTQGPDTAISYFARYKAGDWVASAQLQAQGALNTSFWKKLTDRVQAGVDMTLSVAPSQSMMGGLTKEGITTFGAKYDFRMSTFRAQIDSKGKLSCLLEKRLGAAPVTLTFAADVDHVTQQAKLGMSVSIEASDVDLQEQQEGAQSLNIPF
Protein: M-phase inducer phosphatase (EC 3.1.3.48) (B5LY73)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MDIDMVPGDVSPVYDPFSTGPESALGAPRFTLPELGARGSPCMKSLASPGPMAVLSPVTNLALNMNNLAVLGGQCETPKRKKNLPLLKIPSFASDASSDAGLGLECPSPLDSLDAEQKFEKAMQDATRAVNEKMPIRRIHSLPLQFLGHSPNLRRKNSSPRYGVWTHSHDSANKENMAEENFEFKKPSMPALRCRTRSTGGSKDAFACRPNSAPALMLSPPPTNQPDSPNEISPFILRRPSLSCLQDDDDDDGFLEGLDDVENDSEVPLGMDSLLTAPLVAKQIPETDSPVIRCRPRGLFRSPSMPCAVGRIPLKRPERPQDENTPVRVKRRRSLAGTQVSTTEQEDVVHQVQRSKSFNHSQIERMLDTDPSNVIGDFTKAPALPTVQGKHQELKYITPEIMVKAMSGQFQDLVERLFVIDCRYPYEYEGGHIKGALNLHQEDQIEDYFLRSPILPDCPKKRVLLIFHCEFSSERGPRMCRYVRERDRFVNEYPNLHYPELYILKGGYKEFFQIHKAICEPQMYRPMLHEEFKEDLRKFRLKSRTWAGERSKRDMYSRLKKL
Protein: Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (G3V9S3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|PIRNR:PIRNR000933}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Adenomatous polyposis coli protein
- Pleckstrin homology domain-containing A2.
- Pleckstrin homology domain containing A1
- Rap guanine nucleotide exchange factor 2
Sequence:
MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQEVFRRVSIADPAALGFIISPWSLLLLPSGSVSFTDENVCSQDLRAFTAPEVLQSHSLTSLSDVEKVHIYSLGMTLYWGADHEVPQSQPIKLGDHLNSILLGMCEDVLYARVSVRTVLDACSAHIRNSNCAPSFSYVKQLVKLVLGNISGTDPLSHSSEEKPDRSQAIRDRLRGKGLPIGRSSTSDALDTHKAPLSQQTFLNKGLSKSMGFLSVRDTQEEEDYSKEIPSDNNSRHEDSEPFSSPYQFKTSSPHIDVLSKKKTWASSMDLLCAADRDLSGEIGRYQHCDPETGTGRTSITSRKKEGRYSDGSIALDVFGPQKAEPVIHSRELPASSAVSSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHSDLFSTSSESPSIISSDSDFRQVRKSEASKRFESSSGLPGVDDTVQSRPSRQYETSLEGSLINQEMMLRRQEEEMMQLQARMALRQSRLSLYPGDTIKTSMLDISRDPLREMALETAMTQRKLRNFFGPEFVKTTVEPFASLDLPRSILLQTKKGKSEEQRKKVNIMLLSGQRLELTCDTKTVCRDVFDMVVAHIGLVEHHLFALATLKENEYFFVDPDLKLTKVAPEGWKEEPKRKGKAAVDFTLFFRIKFFMDDVSLIQHSLTCHQYYLQLRKDLLEERIHCDDEASLLLASLALQAEYGDYQPEVHGLSYFRLEHYLPARVMEKLDMSYIKEELPKLHNTYAGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRALVLRFPWRETKKISFSKKKITLQNTSDGIKHAFQTDSSKACQYLLQLCSSQHKFQLQMRARQSNQDAQDLERASFRSLNLQAESVRGFNVGRAISTGSLASSTFNKLAVRPLSVQAEILKRLSCSEWSLYQPLQNSSKEKNDKASWEEKPRGMSKSYHDLSQASLCPHRKQVINMESLPQAFAELVGKPLYPMARSDTESLAGLPQLNNSKSVASLNRSPERRSHESDSSVEDPGQAYVVGMSLPSSGKSSSQVPFKDNDSLHKRWSTVSSPEREITLVNLKKDLKHGLGFQIVGGGKMGRLDLGVFISAVTPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAVDILQNAPEDVTLVISQPKEKPTKVPSTPVHFANGMKNYTKKPSSMQDSAMDPSEDQPWPRGPLRHVPESPFGLSSGLREGSLSSQDSRTESASLSQSHVNGFFTSHLGDRGWQEPQHSSPSPPVTSKITEKTFSDSYRSPARRQGTCDVTELPGCADSDIDDPTYSSSQDRQAPKQEPSSPLKASDKMSFAAFPGPSPEPGDAFEVELAKTDGSLGISVTVLFDKGGVNTSVRHGGIYVKAVIPNGAAETDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQSPTSRERDPASPRCPTPDQDAQSQAPEKMEKQTAHVKDYSFVTEDNTFEVKLFKNSSGLGFSFSREDNLTPELINGSIVRVKKLFPGQPAAESGKINVGDVILKVNGAPLKGLSQQDVISALRGTAPEVSLLLCRPAPGVLPEVNTALLTPLHSPAHAFLNSRKEHSQPSPLSVEQCASSDENGLSGQSKRQCKPPSRRESYSDHSDSGEEESVRAAAKMPNVIPLSAFAPEALRSQGEPASTMFYLPRKIPGKPESESSRLPHPLDVSPGQIRQPPAECAPSDSPGKHLTHLASQLHKEENMTALKNDLGNHLEDSELEVELLITLVKSEKGSLGFTVTKGSQSIGCYVHDVIQDPAKGDGRLRPGDRLVKVNDADVTNMTHTDAVNLLRAAPKTVRLVIGRILELPRMPVFPHLLPDITVTCHGEELGFSLSGGRGSPHGVVYISDINPRSAAAVDCSLQLLDIIHYVNGVSTHGMTLEEANRALDLSLPSVVLKVTRDGCPVVPCSTRSAISALRPLEANGLSSMEPYGQPALTPKKSFSKVNGDGASGAMCPGGKGLSSPRKKSADLMEARESDSRDDDVYDDPQEAEVIQSLLDVVDEEAQNLLNQTKASRRACSPDPLRTNGEASEDGEDTDCDGSPLPEDVPESVNGGGGKACFASLIQASQEEKPVKEEATQESRESTTETTDREDSSKDPLFLTNEELAALPVVRVPPSGKYTGTQLQATIRTLQGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDTTRVPLGDEGGYINASFIRIPVGTQEFVYIACQGPLPTTVGDFWQMVWEQNSTVIAMMTQEVEGEKIKCQRYWPSILGTTTMANERLRLALLRMQQLKGFVVRVMALEDIQTGEVRHISHLNFTAWPDHDTPSHPEDLLTFISYMRHIRRSGPVITHCSAGIGRSGTLICIDVVLGLISQDLEFDISDLVRCMRLQRHGMVQTEGQYVFCYQVVLYVLTHLQAEEQKAQPGLPQ
Protein: Cullin (Q5AJB7)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- SCF ubiquitin ligase complex subunit
- E3 ubiquitin ligase complex SCF subunit
- SCF ubiquitin ligase complex subunit
- Ubiquitin-binding SDF ubiquitin ligase complex subunit
- Defective in cullin neddylation protein 1
- SCF ubiquitin ligase complex subunit
- COP9 signalosome complex subunit 5
- NEDD8 family protein
- Protein phosphatase PP2A regulatory subunit B
- Cullin-associated NEDD8-dissociated protein 1
Sequence:
MSSTLPPFSDLNATWTFIQPGLEYILGAHGEQGVTATVYMNCYTAVYNYCVNKSRRGTTPVSISNNSDNNSYSLAGAEIYKKLEEYLTEFIKNLKRLPNESFLEFYVRKWTRFTIGAVYMNNVFDYMNRYWVQKERSDGRKDVYDVNTLSFIKWKDEMFKPNSKLLIEQILTCIQQQRDNMIVDTNLISSAIKSLVFLSIDIQDLKKPNLIIYVNSFEIPFLEATMEYYAKESAAFLASHNVIDYMKKCETRIGEEVSRSNNYLEERTKKPLLEVLNAALIEKHANEMYDQFLVLLEQNQIDHIQRMYKLLARVQKTLDPLANTLELYIKKEAAAALEEIQTQAENSEAKKKIVEPKVYVHTLISIYNRFNDIVVRAFSKDTKFIKSLDNACRHFVNNNPIATPKPRSPCRTPELLARYADGFLKSNSKDNEMNADNLMIVFKFIAERDSFEEHYRRLLAKRLVNGTSKSEEMEESVIHRLQEENSIEYTSKMTKMFTDIKASDDLKIKFKDGMNVLFDFSPMVLARSTWPFHSSQDYNDLKLAPELKVTIDSFKAMYLQQGKGKQIEWLWNHGRAELKAHLTKGKGGKPFNFIVSQIQLMVLLAYNYSKTYTLDDLVKIVGIKKELLQNHVTPFVKYKLLKEEGDQLVIVDHYPSKKNKVSFIGAITKTKEEDVEEITKEVQQSRTIFLEASIVRIMKSKKSMAPNNLLNEVVVQAGNRFNAKNIDVKRAIDSLIDKEYLKRNGDDYEYIS
Protein: Uncharacterized protein (Q57WU0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MNTTGEPAKAAAPPAVRRRGRGTFNRPLRAEEPTAPNATASHAGDNVSVITTVTTAVLPASTGPSTRVPEEDLAAEYGGQKRDIPLNIRENFGVHEEEQVVDTVRQLLFRGEKRRRYCVIVGNLQNPDRPITLKLFGHKGLKPFKLQNKLIRLVNISVSRPRLIKQTDASKEEQEVWSGGGSDDEVIADAQADTVTKTENDFDNQGSCDHGQQQKWRKEEQEGTPKRDYESEIQRAHERRNPGGDGGVKDGEESQPTIRMSGSEVEKNGSGDMDVKANERPPSQSGEGRDQGWEEKTMDTETRDVDDYANEDVVLPLTVEIRDSTATNIGQPSSIANSPVLTAARFDTLYGYFFREFQHLLQLEDVRMHQVSINLSLGAVYCCLAREGSYITPLKYATFSEFVQRMNEESMQLYFLKDAPICVSRAVDRECGALQSEAAFSLVKIYFFSNERQSRTVARAMWDAHENRFVLLDMENMGVTFTWTVFSVDETDIQNNRKKHQGEGVSNDSGIPDGDSATETDKPMRKKTVAFPFELELRAYRRWKQHTEHPVAPIAEAILDKLSLAEHNLIQYGSTIGYENMDLSKVCDADAESEDFNVESIIVEHTSRVKPRGTDLTVDSTSSLWIENFAAARALRERMAKGLVGNEERSNVKTRHGERSGRKGAPVPNVKPVTPASRLTFFRSRGSTVHWKLRPGYSTEENLSPLSEALHFVQQVLKTANEIEGRSARGGVAPEPL
Protein: Transcription factor GATA-5 (GATA-binding factor 5) (P97489)
Organism: Mus musculus (Mouse)
Function: Transcription factor required during cardiovascular development (By similarity). Plays an important role in the transcriptional program(s) that underlies smooth muscle cell diversity. Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer (By similarity).
Subcellular location: Nucleus.
Interaction partners:
- Homeobox protein Nkx-2.5
- Zinc finger protein ZFPM2
Sequence:
MYQSLALAQSPGQGTYADSGAFLHSSGTGSPVFVAPTRMPSMLPYLPSCEPGSQAPALAAHSSWTQAVAADSSAFGSGSPHPPAAHPPGATTFPFAHSPPGSGSGGSAGVRDGGAFQGALLAREQYPTPLGRPMGASYPTTYPAYMSSDVAPSWTSGAFDSSILHGLQARPGGLPGRRTSFVPDFLEEFPGEGRECVNCGALSTPLWRRDGTGHYLCNACGLYHKMNGVNRPLVRPQKRLSSSRRSGLCCSNCHTATTTLWRRNSEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKNPAKIKGSSGSTANTTASSPTLLNSESSATTLKAESSLASPVCAGPTITSQASSPADESLASSHLEFKFEPEDFAFTSSSMSPQAGLSGVLRQETWCALALA
Protein: Kruppel-like transcription factor (Q9WTQ3)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MVDHLLPVDETFSSPKCPVGYLGDRLASRQPYHMLPSPISEDDSDVSSPCSCASPDSQAFCSCYSAGPGPEAQGSILDFLLSRATLGSGGASGGVGDGSGPVTWGSWRRASVPVKEEHLCFPEFLSGDPDDVSRPFQPTLEEIEEFLEENMEAEVKEAPESSSRDLEACSQLSAGSHRSHLHPESGGRECRIPPPGGTSGGGTQGAGEGSAHDGPMPVLLQIQPVAVKQEAGAGPASPGQAPESVKVAQLLVNIQGQTFALLPQVVPSSNLNLSSKFVRIAPVPIAAKPIGSGSLGPGPAGLLVGQKFPKNPAAELLKMHKCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHIKVHRFPRSSRAVRAIN
Protein: Thioredoxin-like protein (Q8SZ87)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR017199}.
Interaction partners:
- U5 small nuclear ribonucleoprotein 200 kDa helicase
- Pre-mRNA-processing factor 6
- RE11167p
- U4/U6 small nuclear ribonucleoprotein Prp31
- 116 kDa U5 small nuclear ribonucleoprotein component
- Probable ATP-dependent RNA helicase DDX23
- Pre-mRNA-processing-splicing factor 8
- LD40504p
- Small nuclear ribonucleoprotein Sm D3
- U5 small nuclear ribonucleoprotein 40 kDa protein
Sequence:
MSYMLPHLHNGWQVDQAILSEEDRVVVIRFGHDWDPACMKMDEVMYSIAEKVKNFAVIYLVDITEVPDFNKMYELYDPCTVMFFFRNKHIMIDLGTGNNNKINWPLEDKQEMIDIVETVYRGARKGRGLVVSPKDYSTKYRY