wanglab/gogpt-training-data huggingface dataset:
Protein: WD repeat-containing protein 82 (Q9VLN1)
Organism: Drosophila melanogaster (Fruit fly)
Function: Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3. Together with su(sable), part of a transcription termination checkpoint that promotes transcription termination of aberrant RNAs and their subsequent degradation by the nuclear exosome.
Subcellular location: Nucleus {ECO:0000269|PubMed:21694722}.
Interaction partners:
- Histone-lysine N-methyltransferase SETD1
- Retinoblastoma-binding protein 5 homolog
- Set1/Ash2 histone methyltransferase complex subunit ASH2
- RNA polymerase II subunit A C-terminal domain phosphatase SSU72
- CXXC-type zinc finger protein 1
- LD24014p
- Protein dpy-30 homolog
- Cleavage and polyadenylation specificity factor subunit 4
- Cleavage and polyadenylation specificity factor 73
- Probable cleavage and polyadenylation specificity factor subunit 2
Sequence:
MKIKLIDSVVRSFKVAKIFRENTDKINAIDFAPNGEHLISCSEDDQIVIYDCEKGTQSRTVNSKKYGVDLIHFTHANNTAIHSSTKVDDTIRYLSLHDNKYLRYFPGHTKKVISLCISPVEDTFLSGSLDKTLRLWDLRSPNCQGLMHLSGRPIAAYDPEGLIFAAGVNSESIKLYDLRSFDKGPFVTFKLNQEKECDWTGLKFSRDGKTILISTNGSVIRLVDAFHGTPLQTFTGYPNNKGIPIEASFSPDSQFIFSGSTDGRVHIWNADTGNKVSVLNGDHPGPVQCVQFNPKYMMLASACTNMAFWLPTSEEGL
Protein: Larval serum protein 2 (LSP-2) (Hexamerin-2) (Q24388)
Organism: Drosophila melanogaster (Fruit fly)
Function: Larval storage protein (LSP) which may serve as a store of amino acids for synthesis of adult proteins.
Subcellular location: Secreted, extracellular space.
Interaction partners:
- Larval serum protein 1 beta chain
- Larval serum protein 1 alpha chain
- Larval serum protein 1 gamma chain
- General odorant-binding protein 99b
- Fat body protein 2
Sequence:
MKSFTVIALAAVALLATLGQAKHLDSKVADKDFLMKQKFMYQILQHIYQDDVFTTPFGGSYVEYKPWEHVADYVHPEMLEHFFELWQHQPFTDDMVWSVMYDKHEEYVVGLVRLFYFAKNWETFQHVVYWARQHVNKQLFVYAVTIASLFRDDMQGVVLPAHYEIHPWSYFDSQALEWAEHYKMHGFHHVKQMDNIYNVVIRTNYSNVHGSLNYDHDLAYYLEDVGFNAFYYYFNLDYPFWTKGGEEHVLNKDRRGELYLYVHWQLLARWYLERLSHDLGEVPAFNMYVPTESGYASNLRTYYGVPQWHRENHHSFYHEHNYEHIEHVEMYTQRVMDWIHKNEKFDVETINVLGNIIQGNADSVDKKFYGSLDKLYRFIVNEGHHYGHGDESFPGLFMHYDTSMRDPIFYEVYKTIVSHYWHLMETYPEYHKKDYAFEGVHIDAVHMPESLTTYFEHFDSDISNAVNVEPAVEGSADPLYTFGRNSHYKGSSYVIKARQQRLNHKPFEFTLDVTSDKAQDAVVKVFIGPKYDEHGHEIPLEHNYQNFFELEHFKVHLEAGVNHIKRASGDFSFWVNDRTTYLELYQKLMDATNSDYKFKLDQSEAHCGVPNRMMLPRGKKGGQVFQFFYMVYPYHQPEVAQFTGYDPVVSCGVGHGSRYVDALPFGFPFNRPVKHDYYFDVHNFKFVDVKIFHRDEHTNVV
Protein: Tachykinin-related peptide 6 (TKRP-6) (P86581)
Organism: Oncopeltus fasciatus (Large milkweed bug)
Subcellular location: Secreted {ECO:0000269|PubMed:19084564, ECO:0000305}.
Interaction partners:
Sequence:
APSMGFMGMR
Protein: Actin-interacting protein 1 (AIP1) (Protein flare) (Q9VU68)
Organism: Drosophila melanogaster (Fruit fly)
Function: Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. Together with GMF, promotes Arp2/3-nucleated actin filament array disassembly. Essential for organismal and cell viability. Required for the development of normal wing cell planar polarity. In egg chambers and together with GMF, plays an important role in directional migration of border cell clusters.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:17565945}. Note=At the cell periphery of wing cells.
Interaction partners:
- Multiple wing hairs, isoform C
- Cofilin/actin-depolymerizing factor homolog
- IP04855p
- Adenylyl cyclase-associated protein
- F-actin-capping protein subunit beta
- Actin-related protein 3
- Profilin
- Glia maturation factor
- Filamin-A
- Actin, indirect flight muscle
Sequence:
MAQPQPPAYENKNIYATLPRTQRGQPIVLGADPKGKNFLYTNGNSVIIRNIENPAIADVYTEHSCAVNVAKYSPSGFYIASGDASGKIRIWDTVNKEHLLKNEFQPIAGPIKDISWSPDNQRIVAVGEGRERFGHVFMSETGTSVGEISGQSKSINSADFRPARPFRIVTGSEDNTIAVFEGPPFKFKMTKQDHSRFVQAVRYSPDGKFFASAGFDGKVFLYDGTSSELVGEFGSPAHKGGVYALAWKPDSTQLLTCSGDKTCRLWTVESRELVSEFVMGTTVDDQQVSCLWQGDNLITVSLSGVITYLNVADPSKPLRVVKGHNKPITVLGLSDDRSTIYTGSHDGVVTNWNSGSGTNDRITGTGHGNQINGIAAWGDFVYTCGIDDSLRQFSVEGNSYTDYVVKLNCQPRGLAILRNENIIALACIKELTLVQDQKKIFSLPIKYEASSIAVNADTSDVAVGGDDQKLHIYTLKGGVLEPKVELDHLGAVTDVSYSPDLKYLVACDAHRKVVLYSVEEYKPAHNKEWGFHSARVNTVAWSPNSLLVASGSLDTTIIIWSVANPAKHTIIKNAHPQSQITRLVWLDNNTVISTGQDCNTKVWHVENI
Protein: ESAT-6-like protein EsxL (P9WNJ5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Induces apoptosis of host cells. Is immunogenic with highly specific seroreactivity towards TB patients' serum.
Subcellular location: Secreted {ECO:0000269|PubMed:17443846}. Note=Probably secreted via the ESX-5 / type VII secretion system (T7SS) (Probable). Secretion may depend on complex formation with EsxK (Probable). {ECO:0000305|PubMed:19876390, ECO:0000305|PubMed:27751956}.
Interaction partners:
- ESAT-6-like protein EsxK
- ESAT-6-like protein EsxJ
- PPE family protein PPE18
- 6 kDa early secretory antigenic target
- ESAT-6-like protein EsxP
- ESAT-6-like protein EsxN
- ESAT-6-like protein EsxO
- ESAT-6-like protein EsxB
- ESAT-6-like protein EsxW
- ESAT-6-like protein EsxI
Sequence:
MTINYQFGDVDAHGAMIRAQAGLLEAEHQAIIRDVLTASDFWGGAGSAACQGFITQLGRNFQVIYEQANAHGQKVQAAGNNMAQTDSAVGSSWA
Protein: Cystathionine beta-synthase (EC 4.2.1.22) (Beta-thionase) (Serine sulfhydrase) (Q91WT9)
Organism: Mus musculus (Mouse)
Function: Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (By similarity). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P35520}. Nucleus {ECO:0000250|UniProtKB:P35520}.
Interaction partners:
- Cystathionine gamma-lyase
- Betaine--homocysteine S-methyltransferase 1
- Methionine synthase
- Adenosylhomocysteinase
- Serine hydroxymethyltransferase, cytosolic
- Serine hydroxymethyltransferase, mitochondrial
- S-methylmethionine--homocysteine S-methyltransferase BHMT2
- Phosphoserine phosphatase
- Probable cysteine--tRNA ligase, mitochondrial
- Putative adenosylhomocysteinase 3
Sequence:
MPSGTSQCEDGSAGGFQHLDMHSEKRQLEKGPSGDKDRVWIRPDTPSRCTWQLGRAMADSPHYHTVLTKSPKILPDILRKIGNTPMVRINKISKNAGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERAGNLKPGDTIIEPTSGNTGIGLALAAAVKGYRCIIVMPEKMSMEKVDVLRALGAEIVRTPTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDDTAEEILQQCDGKLDMLVASAGTGGTITGIARKLKEKCPGCKIIGVDPEGSILAEPEELNQTEQTAYEVEGIGYDFIPTVLDRAVVDKWFKSNDEDSFAFARMLIAQEGLLCGGSSGSAMAVAVKAARELQEGQRCVVILPDSVRNYMSKFLSDKWMLQKGFMKEELSVKRPWWWRLRVQELSLSAPLTVLPTVTCEDTIAILREKGFDQAPVVNESGAILGMVTLGNMLSSLLAGKVRPSDEVCKVLYKQFKPIHLTDTLGTLSHILEMDHFALVVHEQIQSRDQAWSGVVGGPTDCSNGMSSKQQMVFGVVTAIDLLNFVAAREQTQT
Protein: Lipoyl synthase (EC 2.8.1.8) (Lip-syn) (LS) (Lipoate synthase) (Lipoic acid synthase) (Sulfur insertion protein LipA) (O32129)
Organism: Bacillus subtilis (strain 168)
Function: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00206}.
Interaction partners:
- Lipoate-protein ligase LplJ
- Octanoyltransferase LipM
- Glycine cleavage system H protein
- Octanoyl-[GcvH]:protein N-octanoyltransferase
- Biotin synthase
Sequence:
MAKKDEHLRKPEWLKIKLNTNENYTGLKKLMRENNLHTVCEEAKCPNIHECWAVRRTATFMILGSVCTRACRFCAVKTGLPTELDLQEPERVADSVALMNLKHAVITAVARDDQKDGGAGIFAETVRAIRRKSPFTTIEVLPSDMGGNYDNLKTLMDTRPDILNHNIETVRRLTPRVRARATYDRSLEFLRRAKEMQPDIPTKSSIMIGLGETKEEIIEVMDDLLANNVDIMAIGQYLQPTKKHLKVQKYYHPDEFAELKEIAMQKGFSHCEAGPLVRSSYHADEQVNEASKKRQAQA
Protein: T-box transcription factor T-A (Brachyury protein homolog-A) (No tail protein A-A) (No tail protein-A) (Protein T homolog-A) (T-box protein ZfT-A) (Zf-T-A) (Q07998)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Involved in the transcriptional regulation of genes required for mesoderm differentiation, including itself. Indispensable for the formation of the notochord and the tail structure. Functions together with tbx16/spadetail in development of trunk and tail mesoderm. Functions by itself early in development to repress medial floor plate and promote notochord fate but at later times, functions together with tbx16/spadetail to promote medial floor plate formation. Acts in a parallel pathway to, but cooperates with, non-canonical wnt-signaling during tail formation. Required for the morphogenesis of Kupffer's vesicle and regulates left-right asymmetry.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201, ECO:0000269|PubMed:1295726, ECO:0000269|PubMed:7600949}.
Interaction partners:
- Homeobox protein goosecoid
- Notochord homeobox.
- Forkhead box protein A2
- Homeobox protein MIXL1
- SRY-box containing gene 17
- Chordin
- Bone morphogenetic protein 4.
- Nanog
- POU domain, class 5, transcription factor 1
- Fibroblast growth factor 8
Sequence:
MSASSPDQRLDHLLSAVESEFQKGSEKGDASERDIKLSLEDAELWTKFKELTNEMIVTKTGRRMFPVLRASVTGLDPNAMYSVLLDFVAADNNRWKYVNGEWVPGGKPEPQSPSCVYIHPDSPNFGAHWMKAPVSFSKVKLSNKLNGGGQIMLNSLHKYEPRIHIVKVGGIQKMISSQSFPETQFIAVTAYQNEEITALKIKHNPFAKAFLDAKERSDHKEVPDHSTDNQQSGYSQLGGWFLPSNGPMGPSSSPPQFNGAPVHSSGSYCERYSSLRNHRAAPYPSHYSHRSTTTNNYMDNSSGSLASHDSWSALQIPNSSGMGTLAHTTNTTSNTSQYPSLWSVAGTTLTPSGSASGSITGGLTSQFLRGSSMSYSGLTSSLPVSSPSSMYDPGLSEVGVGDAQFESSIARLTASWAPVAQSY
Protein: Ribonuclease homolog (EC 3.1.27.-) (RSFR) (P30374)
Organism: Gallus gallus (Chicken)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Heterochromatin-associated protein MENT
- Lysozyme g
- Transmembrane protein 140.
- Uncharacterized protein.
Sequence:
MAMSSLWWTAILLLALTVSMCYGVPTYQDFLYKHMDFPKTSFPSNAAYCNVMMVRRGMTAHGRCKSFNTFVHTDPRNLNTLCINQPDQALRTTRRHFRITDCKLIRSHPTCRYSGNQFNRRVRVGCRGGLPVHLDGTSP
Protein: Transcription factor EB (B0QYS6)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MTASSGWEPAPAATMASRIGLRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSSAGNSAPNSPMAMLHIGSNPERELDDVIDNIMRLDDVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSSSCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDVRWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPTTSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSPFHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPLLSTMSPEASKASSRRSSFSMEEGDVL
Protein: TBC1 domain family member 23 (Q9VPW9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Golgi apparatus, trans-Golgi network {ECO:0000256|ARBA:ARBA00004601}.
Interaction partners:
- Cell division cycle 16
- LD02690p
Sequence:
MEENMWIIELESALLDDCTVNDIYGICQGKALPEALRPDVWQVCLDVRHKSDQMSLFNEIYDLPFQSQLREDCQRHVDRMGNDEEDKVSVVSDLESIITFYCKNRNLQYEPDNGWIELLLPLFALKLNRSDTFNLFESIRDTYIPKGCRPKGNVFHVFRLLLLYHDPELCTLLDTKKITPDLYSLTWFQSLFASCSSLSVIIAMWDLYFQNADPFMVFFLALIILINGREQILQMRSSSKEEIIKFLSLMPCALEFDDVPDFCSLAQYYALKTPTSFKTDYLKALYGKQNDTPRSQEEANKVSQALCLPVSVYELVENSATEFPVPDAVRFFLVDCRPAEQYNAGHLSTAFHLDCNLMLQEPVAFATAVQGLLTAQRQAIEANSNAGGEHLCFMGSGRVEEDQYTHMVVASFLQKNTHYVSLLTGGYASIHDYFGDQMADCLEDHNARKCLVCQQHNAQQTKSAPLKTSTPSSTDLFSKFSAAMKSKSAEVKGKLLDIIVNPSANGGATASGTNGVPSAPVQERHVSAKERNGKRYRNVAPVFSIDDENEDALDGAGERDDAPLTSDGKEIVNLNQYFKTADIINAFKCQEVHMSGYMYDSHLIITPGQLVVLRELGRGQAQIMVRRPLASIVKITAKKRHRDLITFKYGFPDGDGLLITDMDRFLIPNAAEVTALISRLIVQVLDDAK
Protein: Ciliary neurotrophic factor receptor subunit alpha (CNTF receptor subunit alpha) (CNTFR-alpha) (P26992)
Organism: Homo sapiens (Human)
Function: Binds to CNTF. The alpha subunit provides the receptor specificity. Receptor for heterodimeric neurotropic cytokine composed of CLCF1/CLC and CRLF1/CLF-1. Acts as a receptor for the neuroprotective peptide humanin as part of a complex with IL6ST/GP130 and IL27RA/WSX1.
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor.
Interaction partners:
- Ciliary neurotrophic factor
- Leukemia inhibitory factor receptor
- Interleukin-27 receptor subunit alpha
- Cardiotrophin-like cytokine factor 1
- Interleukin-6 receptor subunit beta
- Cardiotrophin-1
- Leukemia inhibitory factor
- Interleukin-11
- Interleukin-6 receptor subunit alpha
- Interleukin-6
Sequence:
MAAPVPWACCAVLAAAAAVVYAQRHSPQEAPHVQYERLGSDVTLPCGTANWDAAVTWRVNGTDLAPDLLNGSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMVCEKDPALKNRCHIRYMHLFSTIKYKVSISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKDNEIGTWSDWSVAAHATPWTEEPRHLTTEAQAAETTTSTTSSLAPPPTTKICDPGELGSGGGPSAPFLVSVPITLALAAAAATASSLLI
Protein: Mitogen-activated protein kinase (EC 2.7.11.24) (Q8X1A2)
Organism: Gibberella zeae (Wheat head blight fungus) (Fusarium graminearum)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSRANPPNAAGSRKISFNVSEQYDIQDVVGEGAYGVVCSAIHKPSGQKVAIKKITPFDHSMFCLRTLREMKLLRYFNHENIISILDIQKPRSYESFQEVYLIQELMETDMHRVIRTQDLSDDHCQYFIYQTLRALKAMHSANVLHRDLKPSNLLLNANCDLKVCDFGLARSAASQEDNSGFMTEYVATRWYRAPEIMLTFKEYTKAIDVWSVGCILAEMLSGKPLFPGKDYHHQLTLILDVLGTPTMEDYYGIKSRRAREYIRSLPFKKKVPFRTLFPKTSDLALDLLEKLLAFNPVKRITVEEALKHPYLEPYHDPEDEPTAPPIPEEFFDFDKHKDNLSKEQLKQLIYQVIMW
Protein: Uncharacterized protein (Q57V24)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPGRRGKQRVKRKKSKRQRPSGMERVLIESIHVRKHKERDILKHHIPPSVKPRVKKVSLDATLPMFNAISKNANRSTSSVTMAKGTKSNGTVVGC
Protein: methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) (B2R7W0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSALAARLLQPAHSCSLRLRPFHLAAVRNEAVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVGINSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVGRMCLDQYSMLPATPWGVWEIIKRTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGAHERPGGDATVTISHRYTPKEQLKKHTILADIVISAAGIPNLITADMIKEGAAVIDVGINRVHDPVTAKPKLVGDVDFEGVRQKAGYITPVPGGVGPMTVAMLMKNTIIAAKKVLRLEEREVLKSKELGVATN
Protein: Integrator complex subunit 10 (Int10) (Q9NVR2)
Organism: Homo sapiens (Human)
Function: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex.
Subcellular location: Nucleus {ECO:0000269|PubMed:16239144, ECO:0000269|PubMed:23904267, ECO:0000269|PubMed:39032490}.
Interaction partners:
- Integrator complex subunit 6
- Integrator complex subunit 3
- Integrator complex subunit 5
- Integrator complex subunit 1
- Integrator complex subunit 11
- Integrator complex subunit 9
- Integrator complex subunit 14
- Integrator complex subunit 7
- Integrator complex subunit 4
- Integrator complex subunit 13
Sequence:
MSAQGDCEFLVQRARELVPQDLWAAKAWLITARSLYPADFNIQYEMYTIERNAERTATAGRLLYDMFVNFPDQPVVWREISIITSALRNDSQDKQTQFLRSLFETLPGRVQCEMLLKVTEQCFNTLERSEMLLLLLRRFPETVVQHGVGLGEALLEAETIEEQESPVNCFRKLFVCDVLPLIINNHDVRLPANLLYKYLNKAAEFYINYVTRSTQIENQHQGAQDTSDLMSPSKRSSQKYIIEGLTEKSSQIVDPWERLFKILNVVGMRCEWQMDKGRRSYGDILHRMKDLCRYMNNFDSEAHAKYKNQVVYSTMLVFFKNAFQYVNSIQPSLFQGPNAPSQVPLVLLEDVSNVYGDVEIDRNKHIHKKRKLAEGREKTMSSDDEDCSAKGRNRHIVVNKAELANSTEVLESFKLARESWELLYSLEFLDKEFTRICLAWKTDTWLWLRIFLTDMIIYQGQYKKAIASLHHLAALQGSISQPQITGQGTLEHQRALIQLATCHFALGEYRMTCEKVLDLMCYMVLPIQDGGKSQEEPSKVKPKFRKGSDLKLLPCTSKAIMPYCLHLMLACFKLRAFTDNRDDMALGHVIVLLQQEWPRGENLFLKAVNKICQQGNFQYENFFNYVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIKHHTVTRGITKGVKEDFRLAMERQVSRCGENLMVVLHRFCINEKILLLQTLT
Protein: Protein disulfide-isomerase 5-2 (AtPDIL5-2) (Protein disulfide-isomerase 7-1) (AtPDIL7-1) (Protein disulfide-isomerase 8) (PDI8) (Q94F09)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as a protein-folding catalyst that interacts with nascent polypeptides to catalyze the formation, isomerization, and reduction or oxidation of disulfide bonds.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Endoplasmic reticulum oxidoreductin-1
- Protein disulfide-isomerase 5-1
- Endoplasmic reticulum oxidoreductin-2
- Heat shock 70 kDa protein BIP3
- Calreticulin-3
- Heat shock 70 kDa protein BIP1
- Heat shock 70 kDa protein BIP2
- Calreticulin-1
- Calreticulin-2
Sequence:
MRSLKLLLCWISFLTLSISISASSDDQFTLDGTVLELTDSNFDSAISTFDCIFVDFYAPWCGHCKRLNPELDAAAPILAKLKQPIVIAKLNADKYSRLARKIEIDAFPTLMLYNHGVPMEYYGPRKADLLVRYLKKFVAPDVAVLESDSTVKEFVEDAGTFFPVFIGFGLNESIISGLGRKYKKKAWFAVSKEVSEDTMVSYDFDKAPALVANHPTYNEHSVFYGPFEDGFLEEFVKQSFLPLILPINHDTLKLLKDDERKIVLTIVEDETHESLEKLYKALRAAAHANRDLVFGYVGVKQFEEFVDSFHVDKKTNLPKIVVWDGDEEYDQVTGIETITQEEDHLTQVSRFLEGYREGRTEKKKINGPSFMGFINSMIGIRSVYILVFLVAVIMMLRSLGQVEEPTGVRTATAVRERVDQATTVPEDESSEHKPSDKKED
Protein: ATPase expression protein 2, mitochondrial (P22136)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for translation of the mitochondrial OLI1 transcript coding for the mitochondrial ATP synthase subunit 9.
Subcellular location: Mitochondrion.
Interaction partners:
- ATP synthase subunit 9, mitochondrial
- ATPase expression protein 1, mitochondrial
- Mitochondrial RNA-splicing protein MRS1
Sequence:
MWINRLVKHPSYSVLRFYTKRLCTVSVKSLREFGVLPNSTICHSVYPRRTYVMGRAVINDILIKKSYSTHTVCAIDRSKDENNGSAYDKFEAKGIPIDVHTLKRIISSSGMDESEFSKSISYLFAKTVDPEPKDVLSLEDLSFLLSKLYTQRFQIRRICRDINAKYSEFWFKLFSLYAEKVDAKRNQVNLRNTKLDACEIFDANLMIKNFIELGQLGKAQKILSFILDRNPDILLSPKNADISTIVHFLQLRCGALAPYWKIPDNSEQKQGFLRKMVRLGAKNTSIRLSSTYKAMDHQTLLKIADLALQEKKLLNSEDLLSTLIQSFGHLGQTQILERCIEHIWQISPQEFPSHVVIKHRGCYPSSKILVSILVSFYFNDHDLHRGLSILDSFIKHYPDVKLDALFWRRLFQLSHFAWTPANDKKATSVVRCWHLMKQWYASKRLRPSVDYETLRQLYDIMKKTGNFPLGIDVLRSFKPGIERTRAENAGKVNNIIIKYQKCIIKELVNRGRFSAVREFIDSYGFDRKMTKDLNIFCANRMFLRSKKMKNKIENKKEREKVRLDSFDDDEDDGMIIGSLW
Protein: Uncharacterized HTH-type transcriptional regulator YqhC (Q46855)
Organism: Escherichia coli (strain K12)
Interaction partners:
- NADPH-dependent aldehyde reductase YqhD
- Methylglyoxal reductase DkgA
- Arabinose operon regulatory protein
Sequence:
MLQNCAQSNCRIIPKKLRDMKREEICRLLADKVNKLKNKENSLSGLLPDVRLLYGETPFARTPVMYEPGIIILFSGHKIGYINERVFRYDANEYLLLTVPLPFECETYATSEVPLAGLRLNVDILQLQELLMDIGEDEHFQPSMAASGINSATLSEEILCAAERLLDVMERPLDARILGKQIIREILYYVLTGPCGGALLALVSRQTHFSLISRVLKRIENKYTENLSVEQLAAEANMSVSAFHHNFKSVTSTSPLQYLKNYRLHKARMMIIHDGMKASAAAMRVGYESASQFSREFKRYFGVTPGEDAARMRAMQGN
Protein: Histone deacetylase/AcuC/AphA family protein (Q7MMB6)
Organism: Vibrio vulnificus (strain YJ016)
Interaction partners:
- Chaperone protein HtpG
- RNA polymerase-associated protein RapA
- Uncharacterized protein
- DNA topoisomerase 3
- NAD-dependent protein deacylase
- AnkB protein
Sequence:
MMSIPLIYHPIYSRLPLPEGHRYPIMKYHHLYQAVCRYQQQHLEWQQAFAFYQPEALSIEAIKQVHQQEYVDLLTTGLLPAAKMRRIGFPWSEQLIERTLTSTAGTVLTAEKALQHGVAIHLSGGYHHAHFDYGSGFCLFNDLVMAAHKALEHASVDKVLIIDSDVHHGDGTATLCQRRDDIVTLSFHCDKNFPARKPDSDLDIGLPRECGDEAFLAAFKEVVPMAIRLHQPDLIIYDAGVDIHHEDELGYLNVSTDALYQRDAFLFGQAKASAIPVAAVVGGGYRTDHEALVPLHLQLLNAAFDVYRSTPD
Protein: Cytosol aminopeptidase (EC 3.4.11.1) (Leucine aminopeptidase) (LAP) (EC 3.4.11.10) (Leucyl aminopeptidase) (O68822)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Aminopeptidase N
- Glutathione synthetase
- DNA polymerase III subunit chi
- Probable gamma-glutamyltranspeptidase
- Glutamate--cysteine ligase
- Glutathione hydrolase proenzyme
- Glutathione hydrolase proenzyme
- Putative glutamate--cysteine ligase 2
- Serine hydroxymethyltransferase 3
- Cysteine synthase
Sequence:
MEFLVKSVRPETLKTATLVLAVGEGRKLGASAKAVDDATGGAISAVLKRGDLAGKVGQTLLLQSLPNLKAERVLLVGAGKERELGDRQYRKLASAVLSTLKGLAGADAALALGDLAVKGRDAHAKARLLVETLADGLYVFDRYKSQKAEPLKLKKLTLLADKADSAAVEQGSKEAQAIANGMALTRDLGNLPPNVCHPTFLGEQAKGLAKEFKGLKVEVLDEKKLRELGMGSFLAVAQGSDQPPRLIVLQYNGAKKDQAPHVLVGKGITFDTGGISLKPGLGMDEMKFDMCGAASVFGTFRAVLELQLPINLVGLLACAENMPSGGATRPGDIVTTMSGQTVEILNTDAEGRLVLCDALTYAERFKPQSVIDIATLTGACIVALGSNTSGLMGNNEALVRQLLKAGEFADDRAWQLPLFDEYQEQLDSPFADIANIGGPKAGTITAGCFLSRFAKKYHWAHLDIAGTAWISGGKDKGATGRPVPLLTQYLLERAK
Protein: Tehao, isoform A (Tehao, isoform B) (Q9VJX9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- Protein toll
Sequence:
MLTYLPVVWLFFALLVLRSATGQIIPLPTFCLGLSPQCTCAAEGNVVRFHCPDEYAMLLEVSEPGASLYMSYYASTELQWLPRFNISSLVKIEFDAYIFWPEKFLSDLLKTLGVQTVKTIIFRDRTLETVVTRDVLNSGNGYMETSQPENITTWHFGSVPGLKKFKFFSHVPELQESIFHGFDTLRDLHLSVNVTTLPGNMLSTVNGTLKTLTIESPGIVSFGNPLLRELQQLRNLSLALIHPFHERDKQLQPHFFGSMTNLEEVRLASATSSVNRSMFKGTNKLQLIKMNGNDDLMELPGEIFLDQVNLKTLDLSCNAIVTLHEDVFKGLGNLTLLDLSKNRLTNLSSTIFAPLTSLNVLRLNKNSLTAMSPSVFQDVVSLNYIEMVNTQFYGATLLMNYEAVVCTNDEACQYKSAEWQCDPRCICWVQRSVGSLIVDCRGTSLEELPDLPRTTLLSTVLKVGNNSLTSLPTVSEHSGYANVSGLFLSDNNLTSLGSGDQLPDNLTHLDVRGNQIQSLSDEFLLFLQEPNNTMTLSLSGNPITCGCESLSLLFFVRTNPQRVRDIADIVCTKQKKSFQQMEAFELCPSYVLLISCVVGGLVIVICLLTVFYLMFQQELKIWLYNNNLCLWWVSEEELDKDKTYDAFISYSHKDEELISKLLPKLESGPHPFRLCLHDRDWLVGDCIPEQIVRTVDDSKRVIIVLSQHFIDSVWARMEFRIAYQATLQDKRKRIIIILYRELEHMNGIDSELRAYLKLNTYLKWGDPLFWSKLYYAMPHNRRVLKGQKKHAGPLI
Protein: Cullin 2 (A0A0G2K761)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Elongin-C
- von Hippel-Lindau disease tumor suppressor
- Elongin-B
- E3 ubiquitin-protein ligase RBX1
- Elongin-B
- Hypoxia-inducible factor 1-alpha
- Ubiquitin-like protein NEDD8
- Leucine-rich repeat protein 1
- Protein zer-1 homolog
- Endothelial PAS domain-containing protein 1
Sequence:
MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYAETKIFLENHVRHLYKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQYIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQNILIRMLLREIKNDRGGEDPNQKVIHGVINSFVHVEQYKKKFPLKFYQGIFVSPFLTETGEYYKQEASNLLQESNCSQYMEKVLGRLKDEEIRCRKYLHPSSYTKVIHECQQRMVADHLQFLHSECHSIIRHERKNDMANMYVLLRAVSSGLPHMIEELQRHIHDEGLRATSNLTQEHMPTLFVESVLEVHGKFVQLINTVLNGDQHFMSALDKALTSVVNYREPKSVCKAPELLAKYCDNLLKKSAKGMTENEVEDKLTSFITVFKYIDDKDVFQKFYARMLAKRLIHGLSMSMDSEEAMINKLKQACGYEFTSKLHRMYTDMSVSADLNNKFNNFIRNQDTVIDLGISFQIYVLQAGAWPLTQAPSSTFAIPQELEKSVQMFELFYSQHFSGRKLTWLHYLCTGEVKMNYLGKPYVAMVTTYQMAVLLAFNNSETVSYKELQDSTQMNEKELTKTIKSLLDVKMINHDSEKEDIDAESSFSLNMSFSSKRTKFKITTSMQKDTPQVISQSRARFNPSISMIKKCIEVLIDKQYIERSQASADEYSYVA