wanglab/gogpt-training-data huggingface dataset:
Protein: Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (SERCA1) (SR Ca(2+)-ATPase 1) (EC 7.2.2.10) (Calcium pump 1) (Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase) (O14983)
Organism: Homo sapiens (Human)
Function: Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen (By similarity). Contributes to calcium sequestration involved in muscular excitation/contraction.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P04191}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P04191}. Sarcoplasmic reticulum membrane {ECO:0000250|UniProtKB:P04191}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P04191}.
Interaction partners:
- Sarcolipin
- Phospholamban
- Sarcoplasmic reticulum histidine-rich calcium-binding protein
- Ryanodine receptor 1
- Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
- Sarcoplasmic/endoplasmic reticulum calcium ATPase 3
- Histone acetyltransferase KAT5
- Nuclear receptor ROR-alpha
- Myosin regulatory light chain 11
- Myosin-2
Sequence:
MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGPVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMVLKISLPVIGLDEILKFVARNYLEDPEDERRK
Protein: Nucleoprotein (EC 3.1.13.-) (Nucleocapsid protein) (Protein N) (P13699)
Organism: Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) (LASV)
Function: Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation. Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
Subcellular location: Virion {ECO:0000255|HAMAP-Rule:MF_04085}. Host cytoplasm {ECO:0000255|HAMAP-Rule:MF_04085}.
Interaction partners:
Sequence:
MSASKEIKSFLWTQSLRRELSGYCSNIKLQVVKDAQALLHGLDFSEVSNVQRLMRKERRDDNDLKRLRDLNQAVNNLVELKSTQQKSILRVGTLTSDDLLILAADLEKLKSKVIRTERPLSAGVYMGNLSSQQLDQRRALLNMIGMSGGNQGARAGRDGVVRVWDVKNAELLNNQFGTMPSLTLACLTKQGQVDLNDAVQALTDLGLIYTAKYPNTSDLDRLTQSHPILNMIDTKKSSLNISGYNFSLGAAVKAGACMLDGGNMLETIKVSPQTMDGILKSILKVKKALGMFISDTPGERNPYENILYKICLSGDGWPYIASRTSITGRAWENTVVDLESDGKPQKADSNNSSKSLQSAGFTAGLTYSQLMTLKDAMLQLDPNAKTWMDIEGRPEDPVEIALYQPSSGCYIHFFREPTDLKQFKQDAKYSHGIDVTDLFATQPGLTSAVIDALPRNMVITCQGSDDIRKLLESQGRKDIKLIDIALSKTDSRKYENAVWDQYKDLCHMHTGVVVEKKKRGGKEEITPHCALMDCIMFDAAVSGGLNTSVLRAVLPRDMVFRTSTPRVVL
Protein: Pfmc-2TM Maurer's cleft two transmembrane protein (O97307)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MFHYIYKIYIFTIILCASNLFNNNVVEIGTYKLSYHNGGIQFRILAQKNTNKKSNGNTLTNILLKDKGGKGSKKKNPDDQISSLVSLVDNMNITQEKKDKIKNLSLKYINSRDVKEKNESINELQKYSNNEECKEYMDSYLMHLRMQNDIKCLKRKNLWNNIWINSITLTLIIIMIACVFSVEITSSSALYPAFILLIFIIYIYARYFPEMKIGYKGIKEACKYYFNKKSK
Protein: HIG1 domain-containing protein (Q5AJA1)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
- Cytochrome b-c1 complex subunit 8, mitochondrial
- Cytochrome c oxidase subunit
- Cytochrome c oxidase subunit
- Cytochrome c oxidase subunit 4, mitochondrial
- Cytochrome b-c1 complex reductase subunit, mitochondrial
- Cytochrome c oxidase subunit 1
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Rnr22p
- coproporphyrinogen oxidase
- Cytochrome c oxidase subunit 3
Sequence:
MKLITENEKNDHKSHIMKEGSKGFLIGSVIGLGLIRYFKFKQPLKYNSFNWTVKACLYTMPTLGFTAFLTDNGGTQFFKSRYRSTHLQQEKQVKSQQLDNLSMSEKIIYRLNEHKYKLVVGAWAGFLFGAWKIINKDLLLTKTQKLIHARVYAQAFTIGVLLSTLYLNMKEVELNNKLPQLPQSWERVLQDKGEL
Protein: Cystatin-B (CPI-B) (Liver thiol proteinase inhibitor) (Stefin-B) (P04080)
Organism: Homo sapiens (Human)
Function: This is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11139332}. Nucleus {ECO:0000269|PubMed:11139332}.
Interaction partners:
- Procathepsin L
- Cathepsin B
- Cathepsin S
- Ribosomal RNA processing protein 1 homolog B
- Cystatin-C
- E3 ubiquitin-protein ligase NHLRC1
- Ribosomal RNA processing protein 1 homolog A
- Prickle-like protein 1
- Trafficking protein particle complex subunit 10
- Apolipoprotein D
Sequence:
MMCGAPSATQPATAETQHIADQVRSQLEEKENKKFPVFKAVSFKSQVVAGTNYFIKVHVGDEDFVHLRVFQSLPHENKPLTLSNYQTNKAKHDELTYF
Protein: V-type proton ATPase subunit f (V-ATPase subunit f) (Q8NIQ1)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Accessory component of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P0C5R9}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- V-type proton ATPase subunit e
Sequence:
MKPLVSPGLAKACTGLSLIGIVFLLVLSYLFSIEAETLMHDLVGSGLTGKQVAKTCLGAVVIYAVFFLFCGSQVIVSRYQKPVRI
Protein: Eukaryotic translation initiation factor 2A (eIF-2A) (Q19052)
Organism: Caenorhabditis elegans
Function: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.
Interaction partners:
- Eukaryotic translation initiation factor 3 subunit B
- Eukaryotic translation initiation factor 2-alpha kinase gcn-2
- Eukaryotic translation initiation factor 5B
- BZIP domain-containing protein.
- Small ribosomal subunit protein uS19
Sequence:
MGDNLVYAVRSSEGFYLKRGLGKDAVTVFEQNKTSRDVACNVFAYSNNGQLFAYCDNQVTRVFEIATNKEILCVELKRTRKILFSPKDNFLLTFEPWAVYGPKTAENQKPEPNVRVYSLADGKHVSTFSAPKEASWEPQFSDDESLAARMVGSEVFFYTNMSFDRYDHKLVEKGATNFALSPGPAPNHVAVYVPAVGSTPARVRVHRVSESFPVVGNRTFFKSDKAVMTWNQRGQSLLILASVEVDKTNQSYYGEQSLYLINIQSGESVVVPLEKKGPIYAAKWNPNGREFAVCYGYMPAKVTFYNPRGVPIFDTIEGPRNDVFYNAFGNIVLICGFGNIAKGKMEFWDVETKKEIISIEVPNTTLFDWAPDGQHFVTCTTAPRLRIDNSYRFWHYTGRMLAETHFESPKELWEVRWRPMTGYNKFAIKELTKTDKMAAGLPIRKKDASHPLNNVPAGAVRQAGAYIPPHLRKPLGGGGSAGPPSAAAPTPGNQNQRPAQPRANGNGNAPQPFRPQQSEQERKAFQLKKKVEEIKVLKQRVANGDQLQPNQMEKIQRENEYLSELSKLTI
Protein: Leucine-responsive regulatory protein (Q9HTP6)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Probable transcriptional regulator
- Putative Fis-like DNA-binding protein
- RNA polymerase sigma factor RpoS
Sequence:
MRTQHQSKRELDKIDRNILRILQEEGRISFTELGERVGLSTTPCTERVRRLEREGLIMGYHARLNPQHLKASLLVFVEISLDYKSGDTFEEFRRAVLKLPHVLECHLVSGHFDYLVKARISEMASYRKLLGDILLKLPHVRESKSYIVMEEVKESLDLPVPD
Protein: Mitochondrial pyruvate carrier (Q38FF5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004448, ECO:0000256|RuleBase:RU363100}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004448, ECO:0000256|RuleBase:RU363100}.
Interaction partners:
- Mitochondrial pyruvate carrier
Sequence:
MVSATAVRRFGYVGAAANWLIPLAAIVNLPTRKPSEIDPLMTGVLGTYSAVFVRWSIAISPPNYPLFLCHATNCVVQAATLVRKAV
Protein: Colony stimulating factor 2 receptor subunit alpha (A0A0G2KAL6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MSIIPLPQLLALLCCCGLAAATQGPTDPSTPPNLGLAHFHNLTFDPGTWTLSWACGGHDGAVMSCTVIDQEAGIRRRVRSRGCRCRFQPMELHRGVDLEVAGDKGHAQVHQTLRFENEGAPGSGAENLTCEILAAHFLCCYWAVGPAAPDDIRYSLRVLNATGHEVASCSAAPGTPPTRCQADDLTHLPRLAYIVVTGQSRTGLVRFLDAVVNTKGIERLGPPDNVSASCNFSHCTITWAPPPTWAPMTEQDFRFEIEWKSCPPLSSSTQKAEPSSIAQKVVIAGREDNAFAFPSPAPRGRLWVRVRAGDTRSDRWSDWSPALELGSEATTPPRALVLAASSCAALLCALALGAACRRLALSRRLLPPIPGIRDRVSDDERVNSETLRKDLLRP
Protein: Protein yippee-like 3 (P61236)
Organism: Homo sapiens (Human)
Function: Involved in proliferation and apoptosis in myeloid precursor cells.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:15556292}.
Interaction partners:
Sequence:
MVRISKPKTFQAYLDDCHRRYSCAHCRAHLANHDDLISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIHCENCKTTLGWKYEQAFESSQKYKEGKYIIELNHMIKDNGWD
Protein: Bridge-like lipid transfer protein family member 3A (ICBP90-binding protein 1) (UHRF1-binding protein 1) (Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1) (Q6BDS2)
Organism: Homo sapiens (Human)
Function: Tube-forming lipid transport protein which probably mediates the transfer of lipids between membranes at organelle contact sites. May be involved in the retrograde traffic of vesicle clusters in the endocytic pathway to the Golgi complex.
Subcellular location: Late endosome {ECO:0000269|PubMed:35499567}.
Interaction partners:
Sequence:
MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGQLTNLELDEEVLQNVLELPTWLAITRVYCNRASIRIQWTKLKTHPICLCLDKVEVEMKTCEDPRPPNGQSPIALASGQSEYGFAEKVVEGMFIIVNSITIKIHSKAFHASFELWQLQGYSVNPNWQQSDLRLTRITDPCRGEVLTFKEITWQTLRIEADATDNGDQDPVTTPLRLITNQGRIQIALKRRTKDCNVISSKLMFLLDDLLWVLTDSQLKAMMKYAESLSEAMEKSAHQRKSLAPEPVQITPPAPSAQQSWAQAFGGSQGNSNSSSSRLSQYFEKFDVKESSYHLLISRLDLHICDDSQSREPGVSANRLMGGAMQLTFRKMAFDYYPFHWAGDSCKHWVRHCEAMETRGQWAQKLVMEFQSKMEKWHEETGLKPPWHLGVDSLFRRKADSLSSPRKNPLERSPSQGRQPAFQPPAWNRLRSSCMVVRVDDLDIHQVSTAGQPSKKPSTLLSCSRKLHNLPTQVSAIHIEFTEYYFPDNQELPVPCPNLYIQLNGLTFTMDPVSLLWGNLFCLDLYRSLEQFKAIYKLEDSSQKDEHLDIRLDAFWLKVSFPLEKRERAELHRPQALVFSASGMIATNTRHAPHCSCSDLQSLFRGFAAAEFFHSNYDHFPKVPGGFSLLHMLFLHHAFQMDSCLPQPNTLPPQRPKASWDLWSVHFTQISLDFEGTENFKGHTLNFVAPFPLSIWACLPLRWQQAQARKLLLASEGRLKPSASFGSPVQSEALAPDSMSHPRSKTEHDLKSLSGLTEVMEILKEGSSGMDNKGPLTELEDVADVHMLVHSPAHVRVRLDHYQYLALLRLKEVLQRLQEQLTKDTESMTGSPLQNQTACIGVLFPSAEVALLMHPAPGAVDADSAGSDSTSLVDSELSPSEDRELKSDASSDQGPASPEKVLEESSIENQDVSQERPHSNGELQDSGPLAQQLAGKGHEAVESLQAKKLSRTQASSSPAALKPPAGRETAVNGQGELIPLKNIEGELSSAIHMTKDATKEALHATMDLTKEAVSLTKDAFSLGRDRMTSTMHKMLSLPPAKEPMAKTDEGVAAPVSGGAARLRFFSMKRTVSQQSFDGVSLDSSGPEDRISVDSDGSDSFVMLLESESGPESVPPGSLSNVSDNAGVQGSPLVNNYGQGSPAANSSVSPSGEDLIFHPVSVLVLKVNEVSFGIEVRGEDLTVALQAEELTLQQLGTVGLWQFLHGQCPGTCFQESSTLKTGHIRPAVGLRFEVGPGAAVHSPLASQNGFLHLLLHGCDLELLTSVLSGLGPFLEDEEIPVVVPMQIELLNSSITLKDDIPPIYPTSPGPIPITLAMEHVVLKRSDDGVFHIGAAAQDKPSAEVLKSEKRQPPKEQVFLVPTGEVFEQQVKELPILQKELIETKQALANANQDKEKLLQEIRKYNPFFEL
Protein: Protein CADMIUM TOLERANCE 3 (Cd tolerant 3) (OsCDT3) (A2WLC1)
Organism: Oryza sativa subsp. indica (Rice)
Function: Confers resistance to heavy metal ions (e.g. aluminium) by chelating them at the plasma membrane of root cells, thus stopping their entry and reducing their accumulation (By similarity). Binds to and confers tolerance to aluminium (Al) (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q5VRD7}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q5VRD7}.
Interaction partners:
Sequence:
MYNPPAAQEMSYSDHVKKRHEDKGCLYACLFTLCCCFCCYETCECCLECLCCC
Protein: FAD-binding PCMH-type domain-containing protein (C8VCU1)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
Sequence:
MALFLTGYLLLTFTLTLSFSTLRVWAAGRWPDVVAQELGPQLSSLASIITEPGAVESDFERWSAYSAPQPGVVVSVATEEDVAKTVKFCVSNSIRFLAQNGGHGWADTFDLGPNRRGLLIDITQLNTVVFNANRTQVTLGGGVSIGEAVAAAVEHDTLIPTGNCNCVGTLGAILGGGYGNLLGMVGFGVDNVLELKVVLADGEVHTVTPGRQGKDHDLFWALRGAGPNYGIVTSATLKAYPVDSATNITAWMGQLVFSGEQVEAVVQAIEELTLTPEMNIFLYYMTVNGTQRFIATPFYYGDEGEARGRAAFASLLDIGPIEDQTAEVPYARWNDGSDGFCTSGGYKPAYSAALQTQNSVVIMEAYSLDRARALPDDSAAFPGRSRVNFQAVAIPWYYDQGLENSAIAWGETMRALWWETDGLDDPAVYVNFAHGDENLTTIYGENVGQLRAIKARVDPENVFNQWFNLGTGRP
Protein: Olfactomedin-like domain-containing protein (G5EGP1)
Organism: Caenorhabditis elegans
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MVATPEEPSLTRWTLSRRLIVAGEIGNVFLIGVLYLHAYIWLNTLHCEISSFKNPTSPPLSPARVKRENKKMPVDLEDYTIIIGQDTIIPRNVLDRSCSQVHQYCSEKSQRLTGFPGVRGSPGDQGPVGPPGRRGPMGIVGPIGLVGEHGILGEPGRDGKCNCPFPDLYVQRVPIPGPPVIKIEEKMVPVPVVVVKEIEVTKFVPFEPTPPGFGPPDGWAPGMPKPGRTRKLPRYSTVRPPPTPKRKTTQSPIHVVPTEKNITMDDWNAEMNISTPKPYMGPPTLGYNRKECILAAVGIPVLHAESQYGRVGSWMRDALPNSMKTAKRRWVTDGFASPVLYEYEDERQLLDKVQKIKYYVDYLASGTGNVVYNGSYYYHKHGTTSLVRYELETGVQVEAELDPEMSHIDCGRLPDHTFEECNATDRHVWLYDRPHNYVDFAVDENGLWAIYAGADSETMRMAKIEPSLFVVNIWNVEVNTTEIADSFIMCGVWYGLKSANNLQTQITHAYDLFRNDTIPGQVEWYNPYQGLTMLHYNPLDARLYFFDNSSLLSVNVRIEEDLPEYIDD
Protein: Actin-like protein 9 (Q8CG27)
Organism: Mus musculus (Mouse)
Function: Testis-specic protein that plays an important role in fusion of proacrosomal vesicles and perinuclear theca formation.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q8TC94}. Cytoplasm, cytoskeleton, perinuclear theca {ECO:0000250|UniProtKB:Q8TC94}. Note=Localizes predominantly in the equatorial segment of the sperm head and neck regions, with some localization in the acrosomal segment of the head. Colocalizes in the acrosomal and equatorial segments of sperm with ACTL7A. Colocalizes with PLCZ1 in the equatorial segment of the head of capacitated sperm. {ECO:0000250|UniProtKB:Q8TC94}.
Interaction partners:
- Dynactin subunit 2
Sequence:
MDVNGHPKFQPSPETDGPLPLTSSTLMVSKSLQQDSLSMVGDRLPPKTGAVVIDMGTGTCKVGFAGQSQPTYTVATILGCQPKKQATKDQSELETFIGEAARSRPELRLVKPIRNGIVVDWEAAELIWRHILEHDLQVATHEHPLLFSDPPFSPATNREKLVEVAFESLHSPALYVASQSVLSVYAHGRVNGLVVDTGHGVSYTVPVVQGYNLPHAIQRLDLAGNHLTAFLAEMLLGSGFSLQQEDLDLVENIKHHYCYLAPDFQKEQARPDEECKQSLKLPDGRTVTLGKELFQCPELLFHPPEIPGLSPIGLPAMAEQSLLKVPQELRPHVARNVILCGGSSLFTGLEGRFRAELLHSLSPEDHVVVMAHPNRNLSVWIGGSILASLHAFQSCWVLREQYEERGPQVVYRKCY
Protein: Fibrinogen C domain-containing protein 1 (Q8N539)
Organism: Homo sapiens (Human)
Function: Acetyl group-binding receptor which shows a high-affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated counterparts. Can facilitate the endocytosis of acetylated components.
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MVNDRWKTMGGAAQLEDRPRDKPQRPSCGYVLCTVLLALAVLLAVAVTGAVLFLNHAHAPGTAPPPVVSTGAASANSALVTVERADSSHLSILIDPRCPDLTDSFARLESAQASVLQALTEHQAQPRLVGDQEQELLDTLADQLPRLLARASELQTECMGLRKGHGTLGQGLSALQSEQGRLIQLLSESQGHMAHLVNSVSDILDALQRDRGLGRPRNKADLQRAPARGTRPRGCATGSRPRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR
Protein: Increased recombination centers protein 15 (Q02733)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
- Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
- Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
- Succinate--CoA ligase subunit beta, mitochondrial
- 2-oxoglutarate dehydrogenase, mitochondrial
- Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial
- Pyruvate dehydrogenase complex protein X component, mitochondrial
- Succinate--CoA ligase subunit alpha, mitochondrial
- Isocitrate dehydrogenase subunit 1, mitochondrial
- Isocitrate dehydrogenase subunit 2, mitochondrial
Sequence:
MGGEDEILSTMEDFAAVYDVLVIGCGPGGFTAAMQASQAGLLTACVDQRASLGGAYLVDGAVPSKTLLYESYLYRLLQQQELIEQRGTRLFPAKFDMQAAQSALKHNIEELGNVYKRELSKNNVTVYKGTAAFKDPHHVEIAQRGMKPFIVEAKYIVVATGSAVIQCPGVAIDNDKIISSDKALSLDYIPSRFTIMGGGTIGLEIACIFNNLGSRVTIVESQSEICQNMDNELASATKTLLQCQGIAFLLDTRVQLAEADAAGQLNITLLNKVSKKTYVHHCDVLMVSIGRRPLLKGLDISSIGLDERDFVENVDVQTQSLLKYPHIKPIGDVTLGPMLALKAEEQAIRAIQSIGCTGSDGTSNCGFPPNVLYCQPQIGWVGYTEEGLAKARIPYQKGRVLFSQNVRYNTLLPREENTTVSPFIKVLIDSRDMKILGVHMINDDANELLSQASMAVSLGLTAHDVCKVPFPHPSLSESFKQAVQLAMANGTSPGVHVRE
Protein: Netrin receptor UNC5C (Protein unc-5 homolog 3) (cUNC-5H3) (Protein unc-5 homolog C) (Q7T2Z5)
Organism: Gallus gallus (Chicken)
Function: Receptor for netrin required for axon guidance (By similarity). Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (By similarity). Involved in dorsal root ganglion axon projection towards the spinal cord.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:O08747}; Single-pass type I membrane protein {ECO:0000255}. Cell surface {ECO:0000250|UniProtKB:O95185}. Synapse, synaptosome {ECO:0000250|UniProtKB:Q761X5}. Cell projection, axon {ECO:0000250|UniProtKB:O08747}. Cell projection, dendrite {ECO:0000250|UniProtKB:O08747}. Cell projection, growth cone {ECO:0000250|UniProtKB:O08747}. Cell projection, lamellipodium {ECO:0000250|UniProtKB:O08747}. Cell projection, filopodium {ECO:0000250|UniProtKB:O08747}.
Interaction partners:
- Adhesion G protein-coupled receptor L2
- Adhesion G protein-coupled receptor L3
- Netrin-3
- Netrin-1
- Neogenin
- Fibronectin leucine rich transmembrane protein 2
- Netrin 4.
- Netrin-4
- Cell adhesion molecule DSCAM
Sequence:
MGKGLEGTAARCGLGMGYLLHSVVLPALAVLGASRPGSAAQDDDFFHELPETFPSDPPEPLPHFLIEPEEAYIVKNKPVNLYCKASPATQIYFKCNSEWVHQKDHVVDERVDETSGLIVCEVSIEISRQQVEELFGPEDYWCQCVAWSSAGTTKSRKAYVRIAYLRKTFEQEPLGKEVSLEQEVLLQCRPPEGIPVAEVEWLKNEEVIDPVEDRNFYITIDHNLIIKQARLSDTANYTCVAKNIVAKRKSTTATVIVYVNGGWSTWTEWSACNSRCGRGFQKRTRTCTNPAPLNGGAFCEGQNVQKIACTTLCPVDGKWTSWSKWSTCGTECTHWRRRECTAPAPKNGGKDCEGLVLQSKNCTDGLCMQAAPDSDDVALYVGIVIAVIVCLAISVVVALFVYRKNHRDFESDIIDSSALNGGFQPVNIKAARQDLLAVPPDLTSAAAMYRGPVYALHDVSDKIPMTNSPILDPLPNLKIKVYNTSGAVTPQDELSDFSSKLSPQITQSLLENETLNVKNQSLARQTDPSCTAFGTFNSLGGHLVIPNSGVSLLIPAGAVPQGRVYEMYVTVHRKEGMRPPVEDSQTLLTPVVSCGPPGALLTRPVVLTMHHCAEPNMDDWQIQLKHQAGQGPWEDVVVVGEENFTTPCYIQLDPEACHILTETLSTYALVGQSITKAAAKRLKLAIFGPLSCSSLEYSIRVYCLDDTQDALKEVLQLERQMGGQLLEEPKTLHFKGSTHNLRLSIHDIAHSLWKSKLPAKYQEIPFYHIWSGCQRNLHCTFTLERFSLNTLELVCKLCVRQVEGEGQIFQLNCSVSEEPTGIDYPIMDSAGSITTIVGPNAFSIPLPIRQKLCSSLDAPQTRGHDWRMLAHKLKLDRYLNYFATKSSPTGVILDLWEAQNFPDGNLSMLAAVLEEMGRHETVVSLAAEGNY
Protein: Mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Glucosidase I) (Q4WDB9)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004648, ECO:0000256|RuleBase:RU368089}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004648, ECO:0000256|RuleBase:RU368089}.
Interaction partners:
- Oligosaccharyl transferase subunit
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3
- alpha-glucosidase
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2
- Oligosaccharyltransferase subunit ribophorin II, putative
- Calnexin homolog
- Geranylgeranyl diphosphate synthase
Sequence:
MHFPNLRFLLAPFLYNVVVSGWQASAADDLSVLATETAKANNDSLLWGPYKSNLYFGVRPRIANSLSAGLMWAKVDNYATAQASFRHTCEQNEGMAGYGWDEYDIRKGGRQTIHDTGNSLDLTIDFIKVPGGQHGGSWAARVRGIPREDGSPDQPTSIVFYATLEGLGNLGVATESGPIGYQGDVKLMGYTTELGDFSIDVTAGPETNEHPEHGHPSYEDKPLDRTLVSSSTIAPENLWQVKPIFFAQLKSEVNEMIQRFGQENPPPPAQVFTIKNAPGDGNIHLIQKVFKGAFEFDILFNSGSSPDPVTSDKLTEVISSASQSFSERFNKVLLPQSPFQTAEYSEFSKAMLSNLVGGIGFFHGDDIVDRSAAPEYDEENEGFWEETAEARARAQPVHEGPKDLFTCVPSRPFFPRGFLWDEGFHLIPVIDWDTDLALEIVKSWLNLMDEDGWIAREQILGAEARSKVPPEFTVQYPHYANPPTLFMVLEAFLDKLEASKGAYSQNSGGQEALDSLRMTYLQKPELGEAFIRSIYPLLKRHYFWYRTTQKGDIKSYDREAFSTKEAYRWRGRSVQHILTSGLDDYPRPQPPHPGELHVDLISWMGMMTRAMRRIAEFVGETEDVEEFRGYETAIERNIDDLHWDEEAQTYCDATIDEFEESVHVCHKGYISLFPFLTGMLGPDSPRLKAVLDLIRDPDELWSDYGIRSLSKKDEFYGTAENYWRSPIWMPINYLVVKNLYDIAMTSGPHQEQAREMYSSLRKNLVENVFRQWKETGFAWEQYNPETGKGQRTQHFTGWTSMVVKIMSMPDLPANKQIGHDEL
Protein: LD37276p (Uncharacterized protein, isoform A) (Uncharacterized protein, isoform B) (Uncharacterized protein, isoform C) (Q9I7H8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPYEKFNKKRRQWEDSGVLELIKLWKVCAYELRTIKRNGHLYVAMAKQLTSLGVPVTALEVHFKVNNLTQRYRQEQKTFETTGIISTWKFYSQVDDVFKSLAAHTGYKDKRMTSASNTSSLPSTSESPVWKNPMSQQEFNSNNTEGFYKTEYGMHRHFMDHSQPPPNAGSVDNFMASSAAVAAVAAAASARLADNNMDQQMNTAAGGSGGSGGGGGNTNGGVANYQKIKKSHEDYDKFVDIVKNIVDTHKSTPDKVDTFGDFIKSYMKRWPERLQDEAINHITNYVIVKNMEHSMVSSHNPEGVNNRQ
Protein: Protein VCF2 (VCP nuclear cofactor family member 2) (Q5XKR9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGGCPVRKRRRNGSKEGNHHSTQPKRNKRNPIFQDSQDTEFSWSDNERSSSRINIPERASGPEGNLNQIVTEPDANFPQFLHEGLSKPVYVINWFMSFGPEIKLNTSQQGRNQAV
Protein: Small ribosomal subunit protein uS17y (40S ribosomal protein S11-2) (O65569)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Small ribosomal subunit protein eS30z/eS30y/eS30x
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Small ribosomal subunit protein eS24y
- Small ribosomal subunit protein eS6z
- Small ribosomal subunit protein eS8z
- Small ribosomal subunit protein eS19z
- Small ribosomal subunit protein eS10z
- Small ribosomal subunit protein eS26z
- Small ribosomal subunit protein eS17z
- Small ribosomal subunit protein eS24z
Sequence:
MAEQTEKAFLKQPKVFLSSKKSGKGKRPGKGGNRFWKNIGLGFKTPREAIEGTYIDQKCPFTGTVSIRGRILSGTCHSAKMQRTIIVRRDYLHFVKKYRRYEKRHSNIPAHVSPCFRVKEGDRVTIGQCRPLSKTVRFNVLKVIPAGSSSIGKKAFTGM