wanglab/gogpt-training-data huggingface dataset:
Protein: Rho-GAP domain-containing protein (Q19370)
Organism: Caenorhabditis elegans
Interaction partners:
- Ras-related protein ced-10
- Tyrosine-protein kinase abl-1
- Phosphatidylinositol-3,5-bisphosphate 3-phosphatase mtm-1
- SH3 domain-containing protein
- CRIB domain-containing protein
- Cell division control protein 42 homolog
- tRNA-intron lyase
- CHp/Wrch Rho-like protein homolog
- CED-5
- Tat-binding homolog 7
Sequence:
MTTSSSEGGAGGQHEETSMTLTSSTSADRRCSQDVRKHSQHKQEKAIVHDLECAAKEFRTKMSDQLKCLGDRTDVQMSSLSELQDYFRKRGEIESEYACKLEKLSKSIAQKHKSERSRREGWPQHTSSTVWHTLVEQTKEEYKKRQSLGELYGKQMTASIETRCEDLAKISKRCREIGSYSHNELNRVLTELQTAMKTYQLCYAEMCGIERKKRSAEEDVKRYEDSNPGKYEGSRRHRSLVKYFKRREEKFEVVRLKCTKARNEYLLCVKAANAALHRFFAQDLSYLIDCMDLGMDFWLRALLEKVIDERKKITQHEMDSLASLSTLRSSVDVKADKQKFFEANHQLFMLPKQFEFRPQLGDDIMEVSAEQSLSSDLLQRQLQIEKRLEGLQFEVDEVWKSLEASEKQLLQLYNTQFDGEAGKWRNDLHVTYQYYLKKFEHFLLNGNLMERLEARSASIGEALGKHGISLKSASVGSASERNGSFTTENGGSQNHHLLEERRSKARRIGGIVTKSPDDRPRPKLFGGSLDEYVEATGEEIPLLVQSAIAYLSRYSLRNQGLFRVSGSQSEINRFREAYERGEDLFQYLDDGSDANSAAGVLKLYFRELREPIFPIFMFEQFCDCAKSESPTEFVRRARELVSKLPVSHVLLLRFLFAFLSHLCEFADENMMEPHNLAICFGPTLLPIPEGKDQVFYHNYVNELVRNLIIHADDVFPRDLAGPVYDKYAMQRYMDGNFIEENDLISEDDEAHEKLSLPPSRHMMIDSTYESADRILLSSPILSQANTSTPNGISPSNGAESSTHNEIDYAPIASSRSSNRSKASGSIDLAMRSEMPHRIANELNNIFKNSSLSSEGSKGISVLRHSHVEPSWTDNREHLNMRSMSTDPDEEREYVSPPPPLLSTKYVSAASCSISPAPRTIDIKERKDSRDLLYAPITRATTVPANSGSNTEMNSTGVRPIGKSSLRDQLQLMRKENSTEMKPSTSLNGSTKKLDSETTILDARSTDKSTESSRRTSLEDDKSPEPFAQPDIINSARPRGKSPTLDDILNSLKVATSISP
Protein: Apolipoprotein D (Apo-D) (ApoD) (P23593)
Organism: Rattus norvegicus (Rat)
Function: APOD occurs in the macromolecular complex with lecithin-transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.
Subcellular location: Secreted.
Interaction partners:
- Apolipoprotein A-II
- Clusterin
- Apolipoprotein C-I
- Apolipoprotein E
- Apolipoprotein A-IV
- Apolipoprotein F
- Apolipoprotein M
- Apolipoprotein C-III
- Beta-2-glycoprotein 1
Sequence:
MATMLLLLATLAGLFTTTEGQSFHLGKCPSPPVQENFDVKKYLGRWYEIEKIPVSFEKGNCIQANYSLMENGNIKVLNKELRPDGTLNQVEGEAKQSNMSEPAKLEVQFFSLMPPAPYWILATDYESYALVYSCTTFFWFFHVDYVWILGRNPYLPPETITYLKYILTSNDIDIAKITTKDQANCPDFL
Protein: Glycerate kinase (EC 2.7.1.31) (Q8QZY2)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q8IVS8}.
Interaction partners:
- Glyoxylate reductase/hydroxypyruvate reductase
- 4-trimethylaminobutyraldehyde dehydrogenase
- Phosphoglycerate mutase 1
- Bisphosphoglycerate mutase
- Aldehyde dehydrogenase X, mitochondrial
- Aldehyde dehydrogenase, mitochondrial
- Aldehyde dehydrogenase family 3 member A2
- Alpha-aminoadipic semialdehyde dehydrogenase
- Phosphoglycerate mutase 2
- Pyruvate kinase PKLR
Sequence:
MAAALQVLPCLLRAPSRPLLWGPPVARMTSGMALAEQARQLFDSAVGAVQPGPMLQRTLSLDPSGRQLKVRDRTFQLRENLYLVGFGKAVLGMAAAAEELLAQHLVQGVISVPKGIRAAMEHAGKKEMLLKPHSRVQVFEGAEDNLPDRDALRAALTIQQLAEGLTADDLLLVLISGGGSALLPAPIPPVTLEEKQMLTKLLAARGATIQELNTIRKALSQLKGGGLAQAAYPAQVISLILSDVIGDPLEVIASGPTVASAHSVQDCLHILNHYGLRAALPRSVKTVLSRADSDPHGPHTCGHVLNVIIGSNSLALAEAQRQAEVLGYHAMVLSTAMQGDVKRVARFYGLLARVAAAHLTPSLAERPLEEEAELHQLAAELQLPDLQLEEALEAVAKAKGPVCLLAGGEPTVQLQGSGKGGRNQELALHVGVELGRQPLGPIDVLFLSGGTDGQDGPTKVAGAWVMSDLISQASAESLDIATSLTNNDSYTFFCRFRGGTHLLHTGLTGTNVMDVHLLILHPQ
Protein: LP05465p (Q8MS81)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSHIQCLWVCLGFFMLLVDFIQPIGLNVCNRSQVVTYKRYVERSRVIPYQHRSFWSGWQTKYRTEYYTDEETAYRTVMRPSCCEGYEGSVENCKPVCRQQCPQHGFCSSPNTCSCNAGYGGIDCHPVCPTVCGKNEFCDRPGVCSCQNGYKRTSPSDNCLPVCEKECGHHSFCSEPGKCECEPGYEKVGNGTVFPDGYKNNSNGNCSPICPKDCGQNSRCVRPGVCECENGYAGDDGGTNCRPVCSTCPENGLCLSPGVCVCKPGYVMRNDLCQPHCEKCSDNAHCVAPNQCECFPGYESSGADKKCVPKCSKGCTNGFCFAPETCVCSIGYQMGPNQVCEPKCSLNCVHGKCTSPETCTCDPGYRFKDNSHHECDPICDSGCSNGHCVAPNFCICHDGYQLNSTNPVTSMCQPICKGCQFGDCVAPNVCECNVGYENINGLCELQTTTDSYEYSTTTVELQSSTVDPQLQTSTSEVPHSNCTAGCMCWIEYDGMGTFNTQVCQDLC
Protein: Translocase of outer mitochondrial membrane 5 (F8W8Z9)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004572}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004572}.
Interaction partners:
Sequence:
MFRIEGLAPKLDPEEMKRKMREDVISSIRNFLIYVALLRVSECLPGCDCETSGELTDGHPLTLRGHRGLRTELNGSGEQGGSIYLKEIGQHMKTGHHI
Protein: Leucine-rich repeat LGI family member 4 (LGI1-like protein 3) (Leucine-rich glioma-inactivated protein 4) (Q8N135)
Organism: Homo sapiens (Human)
Function: Component of Schwann cell signaling pathway(s) that controls axon segregation and myelin formation (By similarity).
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Disintegrin and metalloproteinase domain-containing protein 22
- Disintegrin and metalloproteinase domain-containing protein 23
- Disintegrin and metalloproteinase domain-containing protein 11
Sequence:
MGGAGILLLLLAGAGVVVAWRPPKGKCPLRCSCSKDSALCEGSPDLPVSFSPTLLSLSLVRTGVTQLKAGSFLRIPSLHLLLFTSNSFSVIEDDAFAGLSHLQYLFIEDNEIGSISKNALRGLRSLTHLSLANNHLETLPRFLFRGLDTLTHVDLRGNPFQCDCRVLWLLQWMPTVNASVGTGACAGPASLSHMQLHHLDPKTFKCRAIELSWFQTVGESALSVEPFSYQGEPHIVLAQPFAGRCLILSWDYSLQRFRPEEELPAASVVSCKPLVLGPSLFVLAARLWGGSQLWARPSPGLRLAPTQTLAPRRLLRPNDAELLWLEGQPCFVVADASKAGSTTLLCRDGPGFYPHQSLHAWHRDTDAEALELDGRPHLLLASASQRPVLFHWTGGRFERRTDIPEAEDVYATRHFQAGGDVFLCLTRYIGDSMVMRWDGSMFRLLQQLPSRGAHVFQPLLIARDQLAILGSDFAFSQVLRLEPDKGLLEPLQELGPPALVAPRAFAHITMAGRRFLFAACFKGPTQIYQHHEIDLSA
Protein: Alcohol-sensitive RING finger protein 1 (Q06834)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for tolerance to alcohol.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15117954}. Nucleus {ECO:0000269|PubMed:15117954}. Note=Predominantly cytoplasmic. Accumulates in the nucleus specifically upon alcohol stress. Shuttles between the nucleus and the cytoplasm in a XPO1-dependent manner.
Interaction partners:
- Kexin
- DNA-directed RNA polymerase II subunit RPB1
- DNA-directed RNA polymerase II subunit RPB3
- Ubiquitin-conjugating enzyme E2 1
- DNA-directed RNA polymerase II subunit RPB4
- DNA-directed RNA polymerase II subunit RPB2
- DNA-directed RNA polymerase II subunit RPB11
- DNA-directed RNA polymerases I, II, and III subunit RPABC2
- Ubiquitin-ribosomal protein eS31 fusion protein
- DNA-directed RNA polymerase II subunit RPB9
Sequence:
MEECPICLADDQEGEQFGCLNVCGHKFHLNCIREWHKYSINLKCPICRVESTHLEVGEGQHALSINLKMGFMIKNAIDYVGAETTNERNEDDTGEQDQEIEFLSERLRGTLVMDTIKIIQCSICGDTDVSRLSLYCQDCEAIYHETCLRGLACEVGDRNTWQECTDCRSNALLELRMGAISSQLASYDSRNSMIFAGELRDKHSVKTQQMYEQIRNAKHKIQMHVRRALDRYPLPLLRFKDAYKHVNKQVSRKLYRLSDNKYLPDQYDYDSLARTGVHTELLIYCHDE
Protein: Probable CAAX prenyl protease 1 (EC 3.4.24.84) (Prenyl protein-specific endoprotease 1) (PPSEP 1) (Q10071)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Proteolytically removes the C-terminal three residues of farnesylated proteins.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Probable CAAX prenyl protease 2
- Protein farnesyltransferase subunit beta
- Protein-S-isoprenylcysteine O-methyltransferase
- Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit wbp1
Sequence:
MSPGLCFLKEISVIQATPKPTTRSFANCCKMGILQHLMHILDIPGFPWKIVIAGFSIGKYAWDLYLRRRQVPYLLREKPPAILAEHVDEKKYQKALSYARDKSWFSTIVSTFTLAVDLLIIKYDGLSYLWNITKFPWMDKLAASSSRFSLSTSITHSCVFMFGLTLFSRLIQIPFNLYSTFVIEEKYGFNKSTLKIFVIDLLKELSLGGLLMSVVVGVFVKILTKFGDNFIMYAWGAYIVFGLILQTIAPSLIMPLFYKFTPLENGSLRTQIEELAASINFPLKKLYVIDASRRSTHSNAFFYGLPWNKGIVLFDTLVKNHTEPELIAILGHELGHWYMSHNLINTIIDYGMSLFHLFLFAAFIRNNSLYTSFNFITEKPVIVGLLLFSDALGPLSSILTFASNKVSRLCEYQADAFAKQLGYAKDLGDGLIRIHDDNLSPLEFDSLYTSYYHSHPILVDRLNAIDYTTLKKNN
Protein: Integrin subunit alpha 6 (A0A8I6AJE9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
Interaction partners:
Sequence:
MAVAGQLCLLYLSAGLLARLSTAFNLDTREDNVIRKSGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQKANRTGGLYSCDITSRGPCTRIVFDNDADPMSESKEDQWMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETDHDESLVPVPANSYLGLLFLTSLSYTDPDQFVYKTRPPRERPDTSPDVMMNSYLGFSLDSGKGIVSKDDITFVSGAPRANHSGAVVLLKRDMKSAHLLLEYIFDGEGLASSFGYDVAVVDLNADGWQDIVIGAPQYFDRDGEVGGAVYVYINQQGRWSNVKPVRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSPTGIITKPTQVLEGTTPFFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINILKTITVTPSRIDLRQKSMCGSPSGICLKVKACFEYTAKPSGYNPPISILGILEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLNRQKQRACMEETLWLQENIRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSNEAKTVQTDVHFLKEGCGDDNVCNSNLKLEYKFGTREGNQDKFSYLPIQKGIPELVLKDQKDIALEITVTNGPSDPRNPRKDGDDAHEAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSSVTFYLILSTTEVTFDTTDLDINLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLKNLGTATLNIQWPKEISNGKWLLYLMKVESKGLEQVVCEPHNEINFLKLKESHNSRKKRELPEKQIDDSRKFSLFSERKYQTLNCSVNVRCVNIRCPLRGLDSKASLVLRSRLWNSTFLEEYSKLNYLDILVRASIDVTAAAQNIKLPHAGTQVRVTVFPSKTVAQYSGIAWWIILLAVLAGILMLALLVFLLWKCGFFKRSRYDDSVPRYHAVRIRKEEREINDEKHTDNPEKKWPPKWNENESYS
Protein: Zinc finger protein 414 (Q96IQ9)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MEEKPSGPIPDMLATAEPSSSETDKEVLSPAVPAAAPSSSMSEEPGPEQAATPPVWERGGAGGMQQGSSPAPDSCQPGPGPSPGLTSIVSGTSEDLRPPRRRPPPGKQIPCSSPGCCLSFPSVRDLAQHLRTHCPPTQSLEGKLFRCSALSCTETFPSMQELVAHSKLHYKPNRYFKCENCLLRFRTHRSLFKHLHVCAEHAQSPAPPPPPALDREPPAPERPPEVDPASAPGLPFPLLEPFTTPAPAPTGPFLPYLNPAPFGLSPPRLRPFLAAAPGPPASSAAVWKKSQGAGSSPRRPQGGSDAPSGACR
Protein: Mitochondrial import receptor subunit TOM20 homolog (Mitochondrial 20 kDa outer membrane protein) (Outer mitochondrial membrane receptor Tom20) (Q62760)
Organism: Rattus norvegicus (Rat)
Function: Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (By similarity). Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases.
Subcellular location: Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q15388}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Mitochondrial import receptor subunit TOM22 homolog
- Mitochondrial import receptor subunit TOM70
- Mitochondrial import receptor subunit TOM40 homolog
- Mitochondrial import receptor subunit TOM7 homolog
- Translocase of outer mitochondrial membrane 5
- Translocase of outer mitochondrial membrane 6.
- Serine/threonine-protein kinase PINK1, mitochondrial
- Alpha-synuclein
- Mitochondrial import receptor subunit TOM40B
- Non-selective voltage-gated ion channel VDAC1
Sequence:
MVGRNSAIAAGVCGALFIGYCIYFDRKRRSDPNFKNRLRERRKKQKLAKERAGLSKLPDLKDAEAVQKFFLEEIQLGEELLAQGDYEKGVDHLTNAIAVCGQPQQLLQVLQQTLPPPVFQMLLTKLPTISQRIVSAQSLAEDDVE
Protein: Acid-activated urea channel (Urease accessory protein UreI) (P56874)
Organism: Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99)
Function: Functions as a specific, H(+)-activated urea channel that increases the rate of urea entry into the cytoplasm, resulting in activation of cytoplasmic urease at acidic medium pH. Is essential for H.pylori gastric survival and colonization. Is necessary for the adaptation of urease activity to the extracellular pH, as in the presence of urea, UreI rapidly enhances the production of ammonia in the extracellular medium when the pH of the medium was decreased to pH5 or below (By similarity).
Subcellular location: Cell inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MLGLVLLYVGIVLISNGICGLTKVDPKSTAVMNFFVGGLSIVCNVVVITYSALHPTAPVEGAEDIVQVSHHLTSFYGPATGLLFGFTYLYAAINHTFGLDWRPYSWYSLFVAINTVPAAILSHYSDMLDDHKVLGITEGDWWAIIWLAWGVLWLTAFIENILKIPLGKFTPWLAIIEGILTAWIPAWLLFIQHWV
Protein: Troponin I, slow skeletal muscle (A0A060VX54)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
- Troponin C, slow skeletal and cardiac muscles
- Troponin C, slow skeletal and cardiac muscles
- Troponin C, slow skeletal and cardiac muscles
- Troponin C, slow skeletal and cardiac muscles
- Troponin T type 2b
- Uncharacterized protein
- Uncharacterized protein
- Troponin T, slow skeletal muscle
- Troponin T2e, cardiac
- Troponin T2e, cardiac
Sequence:
MGDISTIGLQVQMVSLVKFFRNIGLIFGNLHCQDARASVSRKSKISASRKLMLKSLMVAKAKEEIEQEIVDKEEEKERYLAERAPTLQTGGMSFAELQELCRELHAKVDVVDEERYDIEAKVMHNTREIKDLNIKVLDLRGKFKRPSLRRVRVSADAILRSLLGSKHKVSMDLRANLKSVKKEDTEKEKTVEVSDWRKNVEAMSGMEGRKKMFDAAKGTPQ
Protein: RNA polymerase sigma factor (O51712)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Interaction partners:
- DNA-directed RNA polymerase subunit alpha
- DNA-directed RNA polymerase, omega subunit
- Borrelia oxidative stress regulator protein BosR
- DNA-directed RNA polymerase subunit beta'
- Transcription factor, putative
- RNA polymerase sigma-54 factor
- Translational regulator CsrA
- Glycerol uptake facilitator
- Glycerol kinase
- Divergent polysaccharide deacetylase superfamily
Sequence:
MNIFSNEDLNIYLKSVREHKLITHEEEIKLAGQIQRGNAKAKNKMINANLRLVLKIIKRYAGKGLKIEDLIQEGNLGLIRAAEKYDPNKNTKFSTYASFWIKQSLQRALNTKTRLVKVPYRKENLILQINKYLTEEEKSPKKEEIMKRFNLSPAQYIKIIPYLEKEYSLDKEIEGSENSTLLNLYEDNSFNPEITLEQDSTLKHLNYILETKLNEKERYIIKKRYNLDNSPKKSTLKDISTELGISSETVRQIEKRVLKKLKEEIN
Protein: EGF-like domain-containing protein (H1ZUX1)
Organism: Caenorhabditis elegans
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MEAGGTPSKVPVLAVGTYHRKEAAPILAAAAMLDNSKATTSTAQPSIMSTLTKDKHKEPAPPLPHPSECGQPCVSGQSQMFQHRTTNAQGPPPNRPMPRPPAGMPMMTSSHEHDYTNDYEDPEEMARSRGEGFSNHLLIKTTPPPQPHPNFNSYEMSMSQQRRSQQHQQPMAPPLSDCWGSGVHDSGVLHKNADGAYYIPSGSLRTTSSTLSPASGQRYLDQPHTSGGAPNPTYSDASTTLLKYPLAAGTNQNRRRQQVGTMNNGDPVAGGPMALSKKKKKFDDDSDTCSRWPSKWNILLAAALLVALFVICILLFRAPNYVYTQPAPSSDATSSAAAAASRYQDLGLRALPPAISLGERVDVEFFPKSMATTELTVTKPSRIRFNATVGSGAQLVLLMSAGVHPSLSLHDALFPIRADRIRDSKSPTHIVEEFGSRSRRSLGASSSRHRNIEILSPRSATFEQFVLEGRHYLTFINERSRVEPISFVAEELQRPTTPPKTSSSGTSGAKEHPLASVLVCESNCNQRGECVHGKCHCAPGFTGRTCDEAVCPVVCSGNGVFSGGICVCKSGFKGKECEMRHNWCEVADCNGRGRCDTDGRCRCNPGWTGEACELRACPHASCHDRGVCVNGTCYCMDGWRGNDCSVFADAIVHVPQAQSPPRRGQEPTESSKTRKAQVKPTPTSEKKKESRELQKPIIATVQVPTESSHPCSAHGQLIDDICQCESGWDSVDCSQQACQCVNGDCLDDGSCQCWKGWRGSNCTDKKCAIGCEDRGKCASDGSCKCSSGWNGENCAIDGCPNQCSGKGECGMDRRSSEWSCRCQAGSTGVDCSVSVEMHCDDGLDNDSDGLIDCDDPECCSSSSCSSESVCSTAASPIEVLMRMPPIFNANFAQRVGFLIMEKSVQSYTDSSQFNENLISVIRGRVMWGGSPTGSDDLSTYSNKSTVPLVGVRVSDAAHPLYGFTLTREDGYFDLTVNGARSVTLQFLRTQFQSVKKSVFVSPRQIIHIDDIVLYRQSGGSPPAISMAPARAKCSPTLRRIPDVVLISNWQYTSDGIETDETSDSSRIVVDSRSIFESLPIQGTDVRLVYDSARSPAAPSTMLIGLLYDRVDKELRKVHINIRIAGRRFDRVLAPRTNLTYVFAWDKMNAYRQSESGLVPVTVRVGYEYQGCDRTSERVWQTRRSQMMGATARKMIGTMWTLDIHHHLDIVNNVVEMGNGGYRLITESEPRVSTFAGLDGVKRDVECLKCEGKVDSISLFRPTTVVYAQDGSLIIGDHNMIRRVSQDGQVSTILTLGLADTSHSYYIAVSPVDGTIAISLPLHKQVWRISSLEPQDSRNNYDVLAGDGTVCASAVDSCGDGALAQNAQLIFPKGISFDKMGNLYLADSRRIRVIDTTGHIRSIGETTPDQHPIRTCAQITKLVDLQMEWPTSLTIDPITGSVLVLDTNVVYEIDVVHDVVTIALGSPTTCDLANATSSASAKSLDHRRHLIQNARDITVGTDGAIYVVESDGRRLNQVRKLSSDRSTFSILTGGKSPCSCDVAACGCDDAVSLRDVAASQAHLSSPYAVCVSPSGDVIIADSGNSKIKKVSARMAKYDGRSRTYEVTDAERQEKYTFNRHGQHSSTVSLITGRTFFNFSYQVDSPISMISEIRAASGVVLRVLKRNDSLFDLETTLGQRTTLTMSAYDGTLEQVSKRDSATSRDATKLFYKKGLLTSRIDVATAVGFEYDEYGRAIGLKRDREYWRLGEETISMGSVNTEVLLNGQRFQQVRLGEGNLAVHSTNGATTRLISLRNEGYSLASPLGTSTLYDKSSSIPDSNGEPLISRRRTKVPAIGNPQRRELTTRWDWRHVARRGDDSDGSLGRRKVAEINGVNMFSMEYDVKSNQDTLRLGSTTDDAQALLFIDYTSSGRIRRISAPEDSQMAEMNITWDGAGRKSEVTWGSWKIRLTYDNSNRLTEHAIDGARVPIKMSYAGASRRPNEIQHDGAKWNIQYDNYDRIKEVISKSQEATSFSSIALGGDEWVLKRRTSLNSKPSLVRLSREGKVLESTTPDENHYWLERKDPITGRTTEILNDEETTVVTCWSPEGAPMCSRSRNLQENTTMQGHLVARKSVTIMTPTSSEPSITSSFTYEYDDMLRVTTIQPVIEQSVLESIQLSYDERRGHVAAINGFKWARDASTSRCQGHGLMYETSKANDHRQVVERKLIFGDARASIKIIRDKAGRASESHLEISSSGTQRNQKITRTFDAAGRVASVEQNDQEPVRIIWNSDARVEKINDRVVEWNRGGALKTFQDISYQVDSIGWVVKRDNTTVFGYDGKGRLVSARSSQLRINIFYDREDRVVQIQNSKDFIHFYYGYIDTPKLVSHFSKNGKISTLFYDDDSVPFAMQSDDGTRYALLTDETSTIKAIIGDSNVLRIIDRSVFGALLPSSSSSHPFLPIGYLGGIEISEISVSILNNGRPLDLYSERYMSISPEAVVRLELNEKFSNSIDLMALEIDRQPFRVENVPEDFETWFSLAGLSPNLLPSAHLGLPASSAIVHRLLSSFPRKLRPLTHLTTVLPTRLASDISLTSPTSETSWSIDDVGFSNLLILNEDATTGEVMVEMLSDLKSEEREVISKLFDGVKSLDFATWGLVPTRHLWRAPNSKLELSSTSFSHFTMAVNKDSVELRNGKSKIVVHFSENKAEIVKKIVEELKTRENIAVWRAERKRAEAGEKTWRQWSDRETRELTSKGSVSGYDIEMKPAHQSGLLASVHSWKFRKSE
Protein: AT25231p (Striatin interacting protein, isoform B) (Q8IRD5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Connector of kinase to AP-1, isoform E
- FGFR1 oncogene partner 2 homolog
- CTTNBP2 N-terminal-like protein
- MOB kinase activator-like 4
- Cerebral cavernous malformation 3
- Sarcolemmal membrane-associated protein
- Serine/threonine-protein phosphatase PP2A
- Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit
- non-specific serine/threonine protein kinase
- SD05789p2
Sequence:
MAWKQKNKLLFDTCKNQLSCGAVNARSSMMQSIQSRINVLNTIAASSKRIERASVDTDTHDADANCDGPDLDFVYADVDGYQNEIAELYSYTEFSEFQMNVKAFEDQMELYDLPPNWQKQDSASQRGIVMKLVDQLEVSDRSFRMQAARCILYLAQGCWAEVQSDEEQHQITRDNVLVLYQLGVFASFIDLLNMEIESACSPDIVAVKITNVTLVDSTDIRVILSVLYIITETIRDEKEKGSEDYRELADSFVQEINSPLPDGELLAVKLLGMITRFCSGAAPQFPMKKVVLLLWKVSLLGLGGMDVLKNLKNEYRLKVGLEPITEDTLEVTKCMRASSPPATATDILENQYPKRNFKRSLMKQRFLDEPEQIDMEMGGNEGQNNANNGSGNGGNGEEELSQYYRPYDDPSSSASTTSTANPNNQPSLTQPPAAVPPVQITARLPWTPKVRQKDIDQFLDISRNKFIGYSLIGDHESLAGLPQPIHEGFKTLQRHMYMSLADVQIKKEEDIARNPISTHEDEIKLTPAEVLYQAILPNLPQYMIALLKVLLAASPTSKSKTESINIMADVLPRKMPLTATQSTKLTVDIGRHKEIIVKAVSAIILLYLKHFKINHVYQFEFMSQHLVFANCIPLVLKFFNQTITEYVNTKNSIPLLDFPSCVIGEQPDLSGDSFVYGGEMSDKSYSWRNVFSCINLLRILNKLIKWKHSRVMMLVVFKSAPILKKTLKVRHAMMQLYVLKLLKMQTKYLGRQWRKSNMKTMSAIYAKVRHRLNDDWAFGNDLESRPWDFQAEECTLRACVDRFNLRRYPEATQKCGNNGTAAQNAENAQQSNMMAGNNGCGNNGDANGYGNNGGGGNGGHNQQQQLNDYGVEGGFPSDEILTHSDFAFFGHSGWWDRKVELTDYFKANYAVWLEEEVYNSQTDWDAL
Protein: Adenine phosphoribosyltransferase 4 (AtAPT4) (EC 2.4.2.7) (Q9SU38)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. May contribute to the recycling of adenine into adenylate nucleotides and the inactivation of cytokinins by phosphoribosylation. Possesses low activity toward adenine, but can efficiently convert cytokinins from free bases (active form) to the corresponding nucleotides (inactive form).
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- Adenosine kinase 1
- AMP deaminase
- GMP synthase
- Adenosine kinase 2
- Guanylate kinase 2
- Guanylate kinase 1
- Guanylate kinase 3, chloroplastic
- Inosine triphosphate pyrophosphatase
- Adenylosuccinate lyase
- Adenylosuccinate lyase
Sequence:
MSENEVKDPRIDGIKTKIRVVPDFPKKGIMFQDITTLLLDPKAFKDTIDLFVERYRDMNISVVAGIEARGFIFGSPIALAIGAKFVPLRKPKKLPGQIIFEEYELEYGSDRLEMHVEAVDSGDRALVVDDLIATGGTLCAAMNLLKRVGAEVIECACVIELPELKGRERLEGKPLYVLVEYR
Protein: Protein NIM1-INTERACTING 1 (Protein NIMIN-1) (Q9FNZ5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000269|PubMed:11442055}.
Interaction partners:
- Regulatory protein NPR1
- Protein NIM1-INTERACTING 2
- Protein NIM1-INTERACTING 3
- Regulatory protein NPR3
- Transcription factor TGA2
- Transcription factor TGA5
- Transcription factor TGA6
- Probable WRKY transcription factor 38
- Probable WRKY transcription factor 70
- Isochorismate synthase 1, chloroplastic
Sequence:
MYPKQFSLYNYSLETMSKDENVESKETIRVDKRVREDEEEEEEKKIDTFFKLIKHYQEARKRRREELAENSGVVRRKSNGGERSGIVVPAFQPEDFSQCRTGLKPPLMFVSDHKEENTKVEQEEDQTEERNEDKALDLNLAL
Protein: ARM repeat superfamily protein (O49433)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Integrator complex subunit
- Protein SIEL
- Embryo defective 2739
- Cleavage and polyadenylation specificity factor subunit 3-II
- DNA-directed RNA polymerase II subunit 4
- DNA-directed RNA polymerases II, IV and V subunit 11
- DNA cross-link repair protein SNM1
- Cleavage and polyadenylation specificity factor subunit 3-I
- Nucleic acid-binding, OB-fold-like protein
- DNA-directed RNA polymerases II and V subunit 6B
Sequence:
MEKVSAACAMEWSIKLEKSLRSKNSVKAVEAILETGGKLEQWSKEPESAIAVYNLFGLVPEEDKLFSNTILLRLVDAFCVGDKLIKLAVVRVFMSMFKLSRGKNVNESASWFLSKGRVHNHLELLTRVKNVYDKGDTESKALALILFGCWRDFASEFAPVRYLVFSSMVSPHDLEGRSALFAAACFCEVADDFALVVLGMLNDMVKFPDITPKTRLAAVRVFAKMGCSHTIANRAFKICMKLMLDSPKEDNLVPFLVSLTKLASRSTHLASELAEVIIPFLGEDKTSHARAAVLRCLHFLIERGMCFSLAHERDIASVSSLLKQEELSSDMQVKALQIFQKIVVYKLCMTDASELLQLIAITENASHSQIFSSSCLAISVLVSIWTEIVRTAEKRSIEISSTSLPMQLVVLIMDRVALLGRLCSDLFRAGYAVVSEVQDLLKVLHLLVGKHSELRLLVLEKVRLFLTYIVSLNDGLRKADGAHELLFGVINYKDKRGVVMRSEFLASIHKFLIVFLENLEGDDNLLSEIYEKVKHITEFVSSCSFIDFHTQMIFTLLLHSPILWGFSVNDDTGNSGVSLVADIVNYGIVSLDCSNQILMERNYWPAYRAGVYAARLGAWVTSAMIFDQLKTNVQSDINCCWLKSLTYLSHAEGKFQLLLTPSDSVKLVNWLKNNGYLPELSKDASGEFAHCLALREAYMNLQSSLGMLGNIIASSGVFCFQTWFLVLKTRVLETVLELVECLGLLNQDLRNKNQVEEILLTGCDSLQQLPRISIQLQKLAKEFDMLATCFIDIDDSSSSIITTISLSCSVLAFAAGIVLFLPGFSFQEALVPFTSQSGLCSRLVEDLVRRLWKVDPNVCEKLNILVNTNESLNCFHLQSRNQVLRVCGKVKMLLSICRDALSCTYGLQNQSMSMHKEEIMSEITKSCRHLLSQAIMKWMQIPFGIPKYFFNIRPCVGAELFALSSESSKRIPDTVSVEQGFQLSLDLCLQLKNIKQRQVPVRLNKLYCLLYTKLAYHSPTQHGENNRNQMSYSPWRDEDLIEMSNKLFHHAIKSGKKPDVSGRFDWAKSGVSTVVQFEPNERGQGFSSCLLDVSRFPVGSYQIKWLSCCVDQHGSYWNLLPLNGKPVFTVKKAS
Protein: Casparian strip membrane protein 3 (AtCASP3) (Q9ZQI2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Regulates membrane-cell wall junctions and localized cell wall deposition. Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion.
Subcellular location: Cell membrane {ECO:0000269|PubMed:21593871}; Multi-pass membrane protein {ECO:0000269|PubMed:21593871}. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain.
Interaction partners:
- CASP-like protein 4C1
- Dirigent protein 10
- LRR receptor-like serine/threonine-protein kinase GSO1
- Uclacyanin 1
- Transcription factor MYB36
Sequence:
MDIEKAGSRREEEEPIVQRPKLDKGKGKAHVFAPPMNYNRIMDKHKQEKMSPAGWKRGVAIFDFVLRLIAAITAMAAAAKMATTEETLPFFTQFLQFQADYTDLPTMSSFVIVNSIVGGYLTLSLPFSIVCILRPLAVPPRLFLILCDTVMMGLTLMAASASAAIVYLAHNGNSSSNWLPVCQQFGDFCQGTSGAVVASFIAATLLMFLVILSAFALKRTT