wanglab/gogpt-training-data huggingface dataset:
Protein: Myofilin, isoform O (A0A0B4KG65)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MFKNHLEMIGRNESPSKKAKFWQSYIRSLKGSEDIRAHEAPRASRPYSSYLDSPSYRSIYDEPATANERVQSSGYRYLPVSRDTYGYSPRAIYDHHYSRTTNYDAEKAWNDHLKRMQEIERRYPSRYGLYLRDKPLTPNSLVPLEYEPEDKLLAELNKARRSASPFRPARTTRAGSEPYVPPPSYWNREGSVPRGGPSVFDRATSLAPFTRPSFRASSLEPLDELFERLPIFHPRNRFRDLLSPSPNLPISSIVRDPFWWDVDDLVPFRATSVPRASSPVARDSYLSPVKNRYLWSKHPARPLTPHRSIL
Protein: Peroxidase mlt-7 (EC 1.11.1.7) (Molting defective protein 7) (MoLT-7) [Cleaved into: Peroxidase mlt-7 light chain; Peroxidase mlt-7 heavy chain] (Q23490)
Organism: Caenorhabditis elegans
Function: Plays an essential role in cuticle biogenesis. Required in combination with bli-3 for correct formation of cross-links in cuticle collagens.
Interaction partners:
- Dual oxidase maturation factor 1
- Tetraspanin-15
Sequence:
MRRLHRNLSLLFLICILNEYRIESQTLSPPITDRFKCLTNGCCDHHEWCRFWASIGECNANKDWMTENCQLACGTCTAPAAPLLPVTTTASSFNGGGFVQTTTQSSGPTTTITIPPSSLTSVTSCERVKDSIAQASELMSISRLINPVEDNFGRNMLSIDDITRSVPTGCVPQLSDVGVDCRKSLCYHLMYRTLDGTCNNLEKPMQGAAFRRFNRHFPAQYDDGKGEPISSLNQSRPSAREANRVMLSSAQSVVHDKFNNMMMQWGQFMSHDMSKTTLQPSANCKTCDPVPSKCMPIPIGEKDPNLGFKSKQCLKVSRSAPICRVEPREQLNENTAYIDGSMIYGSSLKDLHKFRDGRTGFLRVTRFNNQNVLPFDQSKCANKDKCTASFTAGDIRANLFIGLSSLHIMFAREHNRIAQKLTELNPTWSGDRVFQEARKIVGAQIQNVLYKEYLPKLLGVSFDKVIGPYKGYDTNVDATIANEFTTSAFRFGHGMIEEFYKRVDLSGNNITHGGFFFGDGVFKSGKILFEGGVDPIIRGFMTTAVKRPHRMTPAITEKMFGSTDLGSLNIQRGRDHGIPSYNKMRQFCGLKSANTFDDFADMILDRNLRAGLARNYNTTNDVDFYVGSMLEDPVIGGLVGTTLSCAIGEQFKRARDGDRFYFENPGIFTRSQMEEIKKSSLSRIICDNADNFELVSQDAFLLPGSNLTPCSKIPKMDLSKWRAL
Protein: Epimerase family protein SDR39U1 homolog, chloroplastic (EC 1.1.1.-) (Protein GIANT CHLOROPLAST 1) (Protein SulA homolog) (AtSulA) (Q9SJU9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Putative NADP-dependent oxidoreductase that acts as positive regulator of chloroplast division. May play a role at an early stage of the division process.
Subcellular location: Plastid, chloroplast inner membrane; Peripheral membrane protein; Stromal side {ECO:0000269|PubMed:15120068}. Plastid, chloroplast {ECO:0000269|PubMed:15208387}.
Interaction partners:
- Golgin candidate 1
- Cell division protein FtsZ homolog 2-1, chloroplastic
- Cell division protein FtsZ homolog 1, chloroplastic
- Protein CLMP1
- Probable histone H2A.2
- Protein C2-DOMAIN ABA-RELATED 8
- Acid phosphatase/vanadium-dependent haloperoxidase-related protein
Sequence:
MELLCSPTSLSSSFALSSALLVPRSFSMPGTRRFMVLCSSQKESQMTVSVTGATGFIGRRLVQRLRADNHAIRVLTRSKSKAEQIFPAKDFPGIVIAEESEWKNCVQGSTAVVNLAGLPISTRWSPEIKKEIKGSRIRVTSKVVDLINNSPAEARPTVLVSATAVGYYGTSETGVFDENSPSGKDYLAEVCREWEGTALKANKDVRVALIRIGVVLGKDGGALAMMIPFFQMFAGGPLGSGQQWFSWIHVDDLVNLIYEALTNPSYKGVINGTAPNPVRLGEMCQQLGSVLSRPSWLPVPDFALKALLGEGATVVLEGQKVLPVRAKELGFEFKYKYVKDALRAIMQ
Protein: Bagpipe homeobox transcription factor Bapx1 (Homeobox protein Nkx-3.2) (NK3 homeobox 2) (Q803Z6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
- Paired box protein Pax-9
- Heart- and neural crest derivatives-expressed protein 2
- Endothelin 1.
- Growth differentiation factor 5
Sequence:
MAVRSNSLMPFSIQAILNRKEESRHLNELDVCFSKSACWKIFDEMDAPERSDETEHKNYDSDSGLSEDNDAKAQIDAKPEKDADLADETDQESAAKGLSDCVSDCNTAEEKSGDAPKQRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRRQMAADLLASAPAAKKVAVKVLVRDDRRQYSPGELLRPPLLSLQPSYYYPYTYCLPAWSLSSACSGNQ
Protein: Chitinase 12 (EC 3.2.1.14) (Q8MLW8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- N-acetyl-D-glucosamine kinase
- beta-N-acetylhexosaminidase
- beta-N-acetylhexosaminidase
Sequence:
MTSFQYVFMIMIFLICGCIAKEYNVFCQYDLGSYYYKGRSQFFEWHLDSRLCTHLVLGSGIGVDGDSGELRITDKILLLEKDKLSSVKTMKWDSIKKVMFTIGGWEEDSSSFSRMVASPKKRDNFYSSMLEFMFRWGFDGVQIDWRYPTLLGGHPDDRQNFVILLEELGLIFRKNQLILMVAVLGRRDNRILESYNIPEIVNHSDFIHLMMHDEQDPYHLRLAYNAPLVGYEGSVTDSIMHWKRNGGAPEKLILGIPLFVRSFTMDRNQSTVGSACKGPGRQTKQSHRPGFMTYNEWCVQQSKWSRMFDQLAKVPYATRGDQWVSYENPRSIWAKMHLLQEHKLGGAMAWTIDVDDFRGRCGEQHGLLRVIFSALGDKNGLTTEKPTTEASGLCPHDGFSRDGWDCRLYHECRDGERIYYECLEGQYFDENQIVCRPAAEVKCDQNFVIWRPGMPVYSYDNMPLNLKIVE
Protein: UPF0758 protein SP_1088 (Q97QW0)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Interaction partners:
Sequence:
MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASVFEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEMESILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILHYAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFSYREKTDLI
Protein: Lambda-carrageenase (EC 3.2.1.162) (Q05JY7)
Organism: Pseudoalteromonas sp
Function: Hydrolyzes lambda-carrageenan with inversion of anomeric configuration. Does not hydrolyze iota- and kappa-carrageenans, agarose or porphyran.
Subcellular location: Secreted {ECO:0000269|PubMed:16926183}.
Interaction partners:
Sequence:
MKIKILSAMIASSLLIGCVIPTVKASQSAIKSIETNRTITKVRTGMLSGGSSIITTSYEGTVAAYKFNGEKLWENELSGFMNHDIWVQDINGDGLVEIFAANADGNVYCINSDGSLKWTFGLNEVPMNSVTVISDADEKYVVAGGYDKNLYYISANGELLKTIESSAYSEEGVFGDGVKPEARTHTVNFVRPVKSSDGTEKLVVLGTNNSLQSSGRFYIFEPFADLPSEKSRISIKKGIGDLRTVDFDNDGNDELTLGNSAQIGDAAISVMNLDDLSQKKSQINDIARRIDRFGYRVAQTEVVMNEGTPTYLTLFGSRILLTPESFDVNDSEILANKYSYYDIWKDKSSNKLVLASAQSGGSQVHIIDTSNPSWKSAYEELEPQGKLAAIQENTREVERQLSNFQKPTRERAPLPVYFISESRNEIPATIERSESLYDSPVFLNYSTLPNVENWDRSEVLADNPKYRDKRDRRKNYTLSSEEMFNKLSAGYESSDGISQWAGHGNDPYMISLATMKRIISSGDGKKTVNIYPEIEGHGDAFNKVLNDHFYPLAEFSSENNANLFMRNKHTFWQSTIYAPEWSELRSGRLADAFVPAMEETTDKSMEMSVAGRMGLWAAGSVDNWGERYARDNPSFDRLRQHSHQMVPNHALRQIIYKIASGARYINNFGFNQEYMSLAWELIGKGALYVPKREELLSLSPVHISMKEPDPIYRETSNNVKWTTFYDEEKDSIPYVFSRLNGTWPGAKTLPWDYSNYAADTKERRLDFIPKFPKGLVLITPVQQGKFKDEGTVRGTLADNMHPIYKDIMKEYITDGKNYYNANGEQVMAADSVRYRQIKNKIEEKSNLLPMTVSGEAAWVVAQSARKHLRLTLVDSGYLNPSNKVAKVKFNSVTPVAIVDVLSGETFSPDSNGVVEIPVLAGAFRFIDVKITEDLRNMQSSTL
Protein: Histone acetyltransferase esa1 (EC 2.3.1.48) (Protein 2-hydroxyisobutyryltransferase esa1) (EC 2.3.1.-) (Protein acetyltransferase esa1) (EC 2.3.1.-) (Protein crotonyltransferase esa1) (EC 2.3.1.-) (C8VBH4)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z (By similarity). Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, and histone H2A to form H2AK4ac and H2AK7ac (By similarity). The NuA4 complex is involved in the DNA damage response and is required for chromosome segregation. The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) through homologous recombination (By similarity). Recruitment to promoters depends on H3K4me. Also acetylates non-histone proteins (By similarity). In addition to protein acetyltransferase, can use different acyl-CoA substrates, such as 2-hydroxyisobutanoyl-CoA (2-hydroxyisobutyryl-CoA) or (2E)-butenoyl-CoA (crotonyl-CoA), and is able to mediate protein 2-hydroxyisobutyrylation and crotonylation, respectively (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:O94446}. Chromosome {ECO:0000250|UniProtKB:O94446}. Note=Following DNA damage, localizes to sites of DNA damage, such as double stand breaks (DSBs). {ECO:0000250|UniProtKB:O94446}.
Interaction partners:
- Enhancer of polycomb-like protein 1
- Chromatin modification-related protein EAF6
- Chromatin modification-related protein
- Actin-related protein 4
- Chromatin modification-related protein eaf1
- 3'-5' exonuclease/helicase
- SWR1-complex protein 4
- RuvB-like helicase 1
- Protein AF-9 homolog
- Chromatin modification-related protein eaf3
Sequence:
MGVRDSHGEAAGTPDPVEKGIATLNTIRIGVKAMVHKDGALRKAEILSIKQRKDGLAFYVHYVDFNKRLDEWVASSRLDLSQEVEWPQPEKPEKKKSGPAKAPSKNKRVRAGSRDVSATPDTLTGKNTNVGKAQRPSKAGGKENRGDETPADLSMLASEAVSADGTPKAVSEDIDMMDASFTDAKEIKEEERALGLMSREEEIEKLRTSGSMTQNPTEVHRVRNLDRLQMGKYDIEPWYFSPYPASFSDAEVVYIDEFCLSYFDNKRAFERHRTKCTLTHPPGNEIYRDDNISFFEVDGRRQRTWCRNLCLLSKLFLDHKTLYYDVDPFLFYCMCTRDETGCHLVGYFSKEKESGEGYNLACILTLPQYQRRGYGRLLISFSYELSKREGKVGSPEKPLSDLGLLGYRQYWRETLVEILLDSGRETVSENELAMLTSMTEKDVHETLVTFKMLRYNKGQWIIVLTDEVIEERNKRLEKEKIKGSRKIDPARLQWKPPVFTASSRTWNW
Protein: Phenylcoumaran benzylic ether reductase PT1 (PCBER-Pt1) (EC 1.23.1.-) (PtPCBER) (Q9LL41)
Organism: Pinus taeda (Loblolly pine)
Function: Oxidoreductase involved in lignan biosynthesis. Catalyzes the NADPH-dependent reduction of phenylcoumaran benzylic ethers. Converts dehydrodiconiferyl alcohol (DDC) to isodihydrodehydrodiconiferyl alcohol (IDDDC), and dihydrodehydrodiconiferyl alcohol (DDDC) to tetrahydrodehydrodiconiferyl alcohol (TDDC).
Interaction partners:
Sequence:
MGSRSRILLIGATGYIGRHVAKASLDLGHPTFLLVRESTASSNSEKAQLLESFKASGANIVHGSIDDHASLVEAVKNVDVVISTVGSLQIESQVNIIKAIKEVGTVKRFFPSEFGNDVDNVHAVEPAKSVFEVKAKVRRAIEAEGIPYTYVSSNCFAGYFLRSLAQAGLTAPPRDKVVILGDGNARVVFVKEEDIGTFTIKAVDDPRTLNKTLYLRLPANTLSLNELVALWEKKIDKTLEKAYVPEEEVLKLIADTPFPANISIAISHSIFVKGDQTNFEIGPAGVEASQLYPDVKYTTVDEYLSNFV
Protein: Armadillo repeat-containing protein wrm-1 (Worm armadillo protein 1) (Q10953)
Organism: Caenorhabditis elegans
Function: Antagonistic role in the Wnt signaling pathway that operates in embryogenesis. When located at the cortex it has been shown to inhibit Wnt signaling during asymmetric cell division but when relocated to the nucleus it shows positive regulation. Has a role in blastomere signaling during endoderm specification. Component of the beta-catenin-lit-1 complex which promotes phosphorylation, down-regulation and subcellular relocation of pop-1. Within the complex, activates lit-1-dependent kinase activity. Can substitute for bar-1 indicating functional redundancy. Appears to have a role in centrosome positioning and can activation transcription in yeast. Involved in the development of distal tip cells (DTC) by regulating the asymmetric distribution of cye-1 and cki-1 between the daughters of Z1.a and Z4.p cells.
Subcellular location: Cytoplasm, cell cortex {ECO:0000269|PubMed:16077003, ECO:0000269|PubMed:17276345, ECO:0000269|PubMed:25569233}. Nucleus {ECO:0000269|PubMed:16077003, ECO:0000269|PubMed:17276345}. Note=Located in the anterior cell cortex before and during asymmetric cell division. After division, located preferentially in the nucleus of the posterior daughter cell. {ECO:0000269|PubMed:16077003, ECO:0000269|PubMed:17276345, ECO:0000269|PubMed:25569233}.
Interaction partners:
- Protein pop-1
- Serine/threonine kinase NLK
- Casein kinase I isoform alpha
- Beta-catenin-like protein hmp-2
- Axin-like protein pry-1
- Adenomatous polyposis coli protein-related protein 1
- Glycogen synthase kinase-3
- Beta-catenin homolog sys-1
- F-box/WD repeat-containing protein lin-23
- Beta-catenin/armadillo-related protein 1
Sequence:
MDVDCAETFSQPCTPLNFNPMTPSTSRVSTPVRPSSTMSARQYSGSPFKAQPQNMEPSNSRVQELREAAVGKRSYTNAWMQGTYAPPQMAGQQQRFSRPPSVIGSTMSHMTNMSEMTAYSYGGLSMLSVNTEMGEFNNFVNQAPYQRALTRVSQVSENQDPTNRQYPMTAPEIIENLESTELINQAAAIRALEPIVKAGGMLQTWGPKGAEPIIRALFQVLIPRPVENENVIRKAFEILHHSILLSNKEIRRIDRMFFRLNAALMDPNGPPVFNVPKPYSIYEIVMTRAIQLDTKFESSAMVLLVHLCCKPHFMKIFFGEDETQQSPAHRRLHKIVIEFAIGNLRRPETKSKNKGLCVSIIKNLSNKNATIKDMSERLGVVSLFHQIMQNEVIHEDLLWSTMQALTVFCGDVKNGTHFVQMGGAQVLCGLLSHGSTRLLHELLKCLRRVSDLPAIQEQDMKESIHCIVQLIGCSDVTIVELATGTLRNIGLHNKMNKAFMVQDGVTSHAIAVLRTSEQFTYQPHANIDLYRKQILSIYENCLSVLNNVTSMAPQDIKESAVSACRMISENADSAYVLLHYFNVGNRKCRKLAVTVMKRVIETVPAFADPFVDLLGTTNEPLPILLLQRAFQSLDEWRKTSVEMMNCDGRSAEQRRELDDRRKDHEDIVKRSVGLLTNLCSQANPRFFHSLKLVLTNGTLNPFQWLTHEMSDGILQEWLAFILSICSRDESLQTFMMYRFLEQAKMTEAFFAELKARRQNSNIQTMLSKIIDLGRHQQRIVSQQHQQHQMQHHRQLM
Protein: Zinc finger CCCH domain-containing protein 16 (AtC3H16) (Q9FWS3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus envelope {ECO:0000269|PubMed:21189294}. Nucleus, nuclear pore complex {ECO:0000305|PubMed:21189294}.
Interaction partners:
- Protein EXPORTIN 1B
- Protein EXPORTIN 1A
- Pyridoxine/pyridoxamine 5'-phosphate oxidase 1, chloroplastic
- mRNA-decapping enzyme-like protein
- Calmodulin-binding transcription activator 3
- Ankyrin repeat-containing protein BDA1
- Calmodulin-binding transcription activator 2
- Calmodulin-binding transcription activator 1
- Calmodulin-binding transcription activator 5
- Ankyrin
Sequence:
MRKELCRNFQRGSCRYGENCRFLHPQQAKPNNPFGFGTQNQQQQQQQQQQNSSNPFGFGVQSGGSSRPNQFQNTWSRTASTPTGGGAAASTQQTGKQTQPADHKCTDPAACKRVMQDDFKNERPMWKLTCYGHWKYFPCDVTGDISYEELRAVAYEEAKRGIPLQSIVERERNLQNSKIAEFENFLRNPYKGSVTANQSPFAATTPSIFPQSSQINSPSPAFSGFNQQTAFSNTNAGGLSSSGPPNAFASFNQQTTFPNTNAGGVSSSGPPNPFASFTQQSNNQQTAFSNTNAGGLSSSGPPNAFASFNKQPNAFSVNTPQPVPSGPSGFQTNPSTTFKPASFGPGPGFATTPQNNNIFGQSTPTPATNTSQNNQTAFNFNVPVASFTAPAINTTNTSSGTELQIGGDPVDSSIWLKEKWNPGEIPEQAPPDAFV
Protein: Axoneme central apparatus protein, putative importin alpha-1 subunit, putative (Q4GYV5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Importin beta-1 subunit, putative
- Importin-alpha re-exporter protein, putative
- HYDIN/VesB/CFA65-like Ig-like domain-containing protein
- RanBD1 domain-containing protein
- Ran-binding protein 1, putative
- Ribosomal RNA-processing protein 8
- SUMO1/Ulp2, putative
- Dynein arm light chain, axonemal, putative
- Uncharacterized protein
- GTP-binding nuclear protein
Sequence:
MPNRQIIQVFEEYQRARVKFVQTVADFASKPQHIDALQQAGVMQLLRPLLLDNVPSIQQSAALALGRLANYNEELAESVVSGDILAQLVYSLGDQSRFYKKSAAFVLRSVARHNAQLAQAVVGSQAVEALVGCLEDFDPTVKESAVWALGYVARHNAHLAQEVVDKGAIPPLVLCVQEPELSLKRTAASTLADIAKHLPELAQAVVDQDAVTHLAPLIGSNDGKLKRQVCQCLAQIAKHSVELAELVVEGEIFPRIFSLLKDSDETVRKNASTCIREVAKHTPELAQLIVNAGGVGALVDYTNESTGSARLPGIMTLGYISAFSETLALAVIVSCGIEPLSNALEKEQEDHIKSAAAWSLGQIGRHSADHAKAVADCNVLPKLLDLYLHPSSSDDLRMKSKRALKNIIQRCVQLPALEPLLHPEAPKNVLKYVCGQFAKVLPTDIAAKREFVANRGLATVQRIQPEPGSKLAEYIQSINNCYPPEIVQYYSPQYAQTFLEKIENYHVQQVQQH
Protein: Uncharacterized WD repeat-containing protein sll1491 (P74598)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Interaction partners:
- WD repeat-containing protein slr1409
- Serine/threonine-protein kinase C
- Serine/threonine-protein kinase F
- PatA subfamily
- 3-chlorobenzoate-3,4-dioxygenase
- Serine/threonine-protein kinase B
- Uncharacterized isomerase slr1019
Sequence:
MNNYFPRLKQFSAPATFFLTVACLVYPGENAHANASTPNPYTVAQTTASPSVAVENLSGFQGIITALNITPDGKYLAVATADNQITLIDLANQEVVYSQRSPVNNFADLAISADGQWLAIAADNNVDVRRVRDGMRVETLVGHTDKVSGVAFSPDGETIVSVSGGDRTIRIWERASGNLIQTLADNLGPTTSVVFTPDGSQFITGAIGQDRTIKFWDANTFELLGTSPQQPGFINGLAVTPDGRKLVGAVRNFVKAWNLADAKELFSVRGPSLEINTIAVSPNNRWVATANKEGTIMIFDLANGKQVTTLRGHQGWVLSLAFSPDGNTLYSGAEDKTVKIWDLSALAR
Protein: NUDIX hydrolase, conserved (Q57Z14)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- 5'-3' exoribonuclease 2
Sequence:
MYRKNVCVVIFNEDLNFLACQRIHEDKFQFVQGGVEEGDADIIRAAYREVHEEVGLFPEDLRLIGEIMPPSGDPHEFRYILHEGANLRHFGYVGQQQRLFLFYTPSSTIQRVRLVPPKGSVAKQEFSHVEWLPIDEIIERCPKEKQHIFVAVSKVAIPMAKAFLKTRSSI
Protein: Adhesion protein (O07257)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Subcellular location: Cell envelope {ECO:0000256|ARBA:ARBA00004196}.
Interaction partners:
- Possible conserved integral membrane protein
- Large ribosomal subunit protein bL28B
- Zinc chaperone Rv0106
- Small ribosomal subunit protein bS18B
- Small ribosomal subunit protein uS14A
- Probable transcriptional regulatory protein
- Divalent metal cation transporter MntH
- Uncharacterized PPE family protein PPE3
- Large ribosomal subunit protein bL33A
Sequence:
MATPVILVTGHEGTAAVTADLLGLLTDHGTATLRSVAPGSVRRADPRPRCHRREQRRRHRASMKSAIHPDHHPRRLPRCPVLRRDQVVLEMIVITMVGRPSGPGERKWDVWGSVARAVTGGHVPVKSILTGAHADPHSYQASPADAAAIVDAELVIYNGGGYDPWVDQVLAGHPGVQAVDAYSLLGAVGDDDAPNEHVFYDPNVAKAVAATIADRLADLDPSNSGNYRANAAEFSRGADAIAISEHAIATTYPDAAVIATEPVVHYLLAAAGLKNRTPATFIAANENGNDPTPADMAAVLDMIAGREVAALLVNPQTPTAATDELQVAARRAGVPITELTETLPSGTDRDQFCAADRPDRRGRSLRADHADRGLSARGHRVGDLLPTALVCHRRSGGRGRPRRASARPGNCVRRTDGRGSRPGCPDRRGTPRDVFADHPRRGGRPGRGCPGRRDRDLGGLRRGFRRRRHPAVAGAWSPGVGVRGHHLVCDLPDLLVAPAAPLTSRSRFRPL
Protein: AT4g29790/F27B13_30 (Serine/arginine repetitive matrix protein) (Q9SZQ2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Transcriptional regulator of RNA polII, SAGA, subunit
- Transcriptional regulator of RNA polII, SAGA, subunit
- SAGA-associated factor 29 homolog B
- SAGA-associated factor 29 homolog A
- Transcriptional adapter ADA2a
- Transcriptional adapter ADA2b
- Transcription initiation factor TFIID subunit 6b
- ARM repeat superfamily protein
- SAGA-associated factor 11
Sequence:
MSAPGKFDYSSGGPERPLYRSNLAAQMERSSSFRETMEHPVSSSHPSMLRSTSPIAQTDVTNFFQCLRFDPKVVAADHKSIRQGDFKRHVNIALGIQGDESPSTPLKGKLIPSPIPEEIKRLKAGLRENNVKARERLKIFNEASSVFNKFFPSVPTKKRSRPEGFSNDRSGDRLALGPGMGKMGIQGQTLPGCFELDQQKLDERPKSGALNKRTRTSMMDVRSNAIVRQSAGVDRDKDTMRLANHNAVQGEDRSSIGIDGWEKSKMKKKRSGIKTDGPSSLASNKAVDGYRDLKQGIPKLAVDSRSRLNGDSNMLRHGAVNGAVPYGRSDSLSQQTGLAARSLLSRDSDHNPLYNEKRERATGSDKERVNLRAVNKSNIHDESNSSSPTSNLKISASVRGPRSGSGLPPKLSPVVHNTPSPSDWDIAGCTNKPPLLSGVPNRKRMTSNRSSSPPVTQWASQRPQKISRVARRTNLVPIVSSNDDIPSSDNMSDVGCSETSFGFYRRSPAASPQMKMKGENSLSTTALSGSEEFSPPEIKSKDKGKQSDEVNGKTSQNVPKVSIPGLQSRKNKLASGEELGDGVRRQGRTGRGFASTRSVNPMGVMKHGTAKQLRSARNGSDKNESRAGRPPTRKLSDRKAYKRQKNTATNATTLDFLDDGHEELLAAVNSAINFAQNFPSSFWKQMERYFCFISDAHINFMKQQGELSFMGTTPGGTSSDFDSHEIFPEELASSKVDSKAAPLYQRLLSALISEDSASVNEDLQFDGFGADVESEFSVLNHMMEFNGYRSDRLEFDELEDDVSVIPLKGVNSSAHHVNGRLSDHLSIDFSDIQYETLGIDEKIYMEAQSIGICLDPMPSISNVEDEGIVDDIKTLEEAICEVVSKKKDMLNRLLKPALEMKERQEKEFERLGYEKLIEMAYEKSKASRRHHSASGKSSATKISKQAAFAFVKRTLERCRQFEETGKSCFSESTFKNIIIAGLTQFEDNPTDKEDILSASTLMGSQPSSSLALPMTQSTENHANSSENALREGRDEMMWSNRMKKRELLLDDVGGKPLSSSTKGKRSERDRDGKGQASSSRGGSTNKIGRPALVNAKGERKSKTKPRQKTTPMFSSSSTCVNIVEQTRTSLSKTTNSNNSEYSNLETLDESEPLDLSHLQIPDGLGGPDDFDTQAGDLSSWLNIDDDALPDTDDLLGLQIPMDDLSDLNMMV
Protein: Cysteine-rich protective antigen (Inactive sialidase CyRPA) (Q8IFM8)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Essential for the invasion of host erythrocytes by blood stage merozoites. Required for the assembly of the PfRH5 adhesion complex (or invasion complex) composed of CyRPA, RH5 and RIPR at the interface between the merozoite and the host erythrocyte membranes. This facilitates the binding of RH5 to host receptor BSG/basigin, which leads to the establishment of a tight junction between the merozoite and host erythrocyte membranes and allows Ca(2+) release into the erythrocyte.
Subcellular location: Secreted {ECO:0000269|PubMed:25583518}. Cytoplasmic vesicle, secretory vesicle, microneme lumen {ECO:0000269|PubMed:25583518}. Cell membrane {ECO:0000269|PubMed:22593616, ECO:0000269|PubMed:25583518}; Peripheral membrane protein {ECO:0000269|PubMed:22593616, ECO:0000269|PubMed:25583518}; Extracellular side {ECO:0000269|PubMed:22593616, ECO:0000269|PubMed:25583518}. Host cell membrane {ECO:0000269|PubMed:25583518, ECO:0000269|PubMed:27374406, ECO:0000269|PubMed:30542156}. Note=In late schizonts, colocalizes with RIPR in the microneme lumen (PubMed:22593616, PubMed:25583518, PubMed:27374406). During merozoite invasion of host erythrocytes, secreted at the merozoite apical surface where it colocalizes with RIPR and RH5 at the interface between the merozoite and the erythrocyte (PubMed:25583518, PubMed:27374406). {ECO:0000269|PubMed:22593616, ECO:0000269|PubMed:25583518, ECO:0000269|PubMed:27374406}.
Interaction partners:
- Reticulocyte-binding protein homolog 5
- Rh5-interacting protein
Sequence:
MIIPFHKKFISFFQIVLVVLLLCRSINCDSRHVFIRTELSFIKNNVPCIRDMFFIYKRELYNICLDDLKGEEDETHIYVQKKVKDSWITLNDLFKETDLTGRPHIFAYVDVEEIIILLCEDEEFSNRKKDMTCHRFYSNDGKEYNNSEITISDYILKDKLLSSYVSLPLKIENREYFLICGVSPYKFKDDNKKDDILCMASHDKGETWGTKIVIKYDNYKLGVQYFFLRPYISKNDLSFHFYVGDNINNVKNVNFIECTHEKDLEFVCSNRDFLKDNKVLQDVSTLNDEYIVSYGNDNNFAECYIFFNNENSILIKPEKYGNTTAGCYGGTFVKIDENRTLFIYSSSQGIYNIHTIYYANYE
Protein: Transmembrane protein (Q38DZ0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- MICOS complex subunit MIC10
- Mitochondrial fission process protein 1
- Thioredoxin domain-containing protein
- Rhodanese domain-containing protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
Sequence:
MLHSSRIVLVALVKKQATTPTVKSDGAHAPSTERTGERVAVYTPTASEAPELLLPYVEPKPFVSTKRLKAFVASMFVGATTIGTAYYLLSKSISTSLEDGNKNLYLQRIIESNRVALQPRPNIVPEFTAPSSFAELQKKMQQHELELDRKRARILDETVMLHAEAGFRMKLWWNTCLAHIQEAGDKLAFLLQERRERAALAHIRESLDEKGYELVKLRCGKTHIW
Protein: LexA repressor 1 (EC 3.4.21.88) (P0A153)
Organism: Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)
Function: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
Interaction partners:
- Protein RecA
- Cell division inhibitor SulA
- DNA polymerase IV
- DNA linked enzyme involved in DNA repair
- DNA repair protein RecN
- Error-prone DNA polymerase
- UvrABC system protein A
- Translesion DNA synthesis-associated protein ImuA
Sequence:
MLKLTPRQAEILAFIKRCLEDNGFPPTRAEIAQELGFKSPNAAEEHLKALARKGAIEMTPGASRGIRIPGLEAKAEEAGLPIIGRVAAGAPILAEQHIEQSCNINPAFFHPQADYLLRVHGMSMKDVGIFDGDLLAVHTCREARNGQIVVARIGDEVTVKRFKREGSKVWLLAENPEFAPIEVDLKEQELVIEGLSVGVIRR
Protein: Allograft inflammatory factor 1-like (D3ZRD9)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell projection, ruffle membrane {ECO:0000256|ARBA:ARBA00004599}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004599}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004599}.
Interaction partners:
Sequence:
MSVALSNRFQGGKAFGLLKARQEKRLEEINREFLCDQKYSDEENLPEKLAAFKEKYMEFDLNNEGEIDLMSLKRMMEKLGVPKTHLEMKKMISEVTGGVSDTISYRDFVNMMLGKRSAVLKLKSQREQPKASWPTSRKRHCQPALKTHPDLLGCHPCPCLSLLLSAIVTQCDMSHALCPRGLTFFFFFISLCKHLLPDLMRLGILSLRPLHSLQPCPLYTKGLTSNQKLERAGRLQTSFPMFEEGPVQVCSSFKVSKLNSGCRFGSGGPLPFSNSQKIQGFLVS
Protein: Muscarinic acetylcholine receptor (Q801M4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|RuleBase:RU361191}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU361191}. Postsynaptic cell membrane {ECO:0000256|RuleBase:RU361191}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU361191}.
Interaction partners:
Sequence:
MDTINFTFWNASDGNETMETADESPYKTVEVVFIVLVAGSLSLVTVIGNILVMLSIKVNRSLQTVNNYFLFSLACADLIIGLCSMNLYTVYIVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLSYPVNRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGGRTVPEKECYIQFFSNAAVTFGTAIAAFYLPVIIMMVLYWQVSRASKSRVKKDNRKPSGGNLDVASSNQIRENSANKPTNNNLTAEETDRGQTQLTDDTINQHDAKLQNGKAPSTASGEAEEAGQANCIPAEEKESSNDSTSGSGAVTNQKEEAAPPSSAAANDSQTSTRHRAKAGGSKLTCIKIITKSPKGDCYAPSNATVEIVPAVERQNHVARKIVKMTKQPPKKKKAPSSREKKVTRTIMAILVAFVATWTPYNVMVLINAFCSSCIPNTVWTIGYWLCYINSTINPACYALCNITFKKTFKQLLLCQYKNIRSTR
Protein: Alternative oxidase, mitochondrial (EC 1.-.-.-) (Q26710)
Organism: Trypanosoma brucei brucei
Function: Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.
Subcellular location: Mitochondrion inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Mitochondrial, possibly in the inner surface of the inner mitochondrial membrane.
Interaction partners:
Sequence:
MFRNHASRITAAAAPWVLRTACRQKSDAKTPVWGHTQLNRLSFLETVPVVPLRVSDESSEDRPTWSLPDIENVAITHKKPNGLVDTLAYRSVRTCRWLFDTFSLYRFGSITESKVISRCLFLETVAGVPGMVGGMLRHLSSLRYMTRDKGWINTLLVEAENERMHLMTFIELRQPGLPLRVSIIITQAIMYLFLLVAYVISPRFVHRFVGYLEEEAVITYTGVMRAIDEGRLRPTKNDVPEVARVYWNLSKNATFRDLINVIRADEAEHRVVNHTFADMHEKRLQNSVNPFVVLKKNPEEMYSNQPSGKTRTDFGSEGAKTASNVNKHV