wanglab/gogpt-training-data huggingface dataset:
Protein: V-type proton ATPase subunit E (V-ATPase subunit E) (Q95X44)
Organism: Caenorhabditis elegans
Function: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Regulates pH homeostasis in the intestine. Probably by regulating cytoplasmic pH, required for cell survival in the intestine and hypodermis. Involved in receptor-mediated endocytosis. Involved in embryogenesis and larval development.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12853134}. Apical cell membrane {ECO:0000269|PubMed:12853134, ECO:0000269|PubMed:16785323}; Peripheral membrane protein {ECO:0000305}. Note=Localizes in clusters in the cytoplasm of the excretory canal (PubMed:12853134). Colocalizes with vha-5 to stacked sheets of the apical cell membrane of syncytial hypodermal cells (PubMed:12853134, PubMed:16785323). {ECO:0000269|PubMed:12853134, ECO:0000269|PubMed:16785323}.
Interaction partners:
- V-type proton ATPase catalytic subunit A
- V-type proton ATPase subunit D
- Probable V-type proton ATPase subunit F
- Probable V-type proton ATPase subunit G
- V-type proton ATPase subunit B 1
- V-type proton ATPase subunit C
- Probable V-type proton ATPase subunit H 2
- V-type proton ATPase subunit
- V-type proton ATPase subunit B 2
- V-type proton ATPase 16 kDa proteolipid subunit c 2
Sequence:
MGISDNDVQKQLRHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQQQRQKIMEFFEKKEKQVELQRKIQASNSLNAGRLRCLKAREDHIGAVLDEARSNLSRISGDAARYPAILKGLVMQGLLQLLEKEVVLRCREKDLRLVEQLLPECLDGLQKEWGSTTKVVLDKQNFLPSESAGGVELSARAGKIKVSSTLESRLELIANQIVPQVRTALFGPNPNRSFFD
Protein: At1g51400/F5D21_10 (F11M15.26 protein) (Photosystem II 5 kD protein) (Q9SYE2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Expressed protein
- Photosystem I reaction center subunit IV B, chloroplastic
- Secreted protein
- Chlorophyll a-b binding protein 3, chloroplastic
- F-box protein At5g07610
- F-box/LRR-repeat protein At3g59210
- F-box/kelch-repeat protein At3g13680
- Putative F-box/FBD/LRR-repeat protein At5g56810
- Putative RING zinc finger protein
- E3 ubiquitin-protein ligase ATL41
Sequence:
MASMTMTSSFLPTVSNLPANISSNSRRSLTVVKASGSENTTSLENKKQEQSMKMRRDLVFTAAAAAVCSLAKVAMADDEPKRGTEAAKKKYAPVCVTMPTAKICRN
Protein: Carboxylesterase 1C (EC 3.1.1.1) (Liver carboxylesterase N) (Lung surfactant convertase) (PES-N) (P23953)
Organism: Mus musculus (Mouse)
Function: Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant.
Subcellular location: Endoplasmic reticulum lumen. Note=Microsomal membrane, lumen of endoplasmic reticulum.
Interaction partners:
- UDP-glucuronosyltransferase
- UDP-glucuronosyltransferase
- Estradiol 17 beta-dehydrogenase 5
- Retinol dehydrogenase 7
- UDP-glucuronosyltransferase 2B17
- Alanine--glyoxylate aminotransferase
- Histidine-rich glycoprotein
- Cytochrome P450 2E1
- Beta-glucuronidase
- Apolipoprotein A-V
Sequence:
MWLHALVWASLAVCPILGHSLLPPVVDTTQGKVLGKYISLEGFEQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNATSYPPMCSQDAGWAKILSDMFSTEKEILPLKISEDCLYLNIYSPADLTKSSQLPVMVWIHGGGLVIGGASPYNGLALSAHENVVVVTIQYRLGIWGLFSTGDEHSPGNWAHLDQLAALRWVQDNIANFGGNPDSVTIFGESSGGISVSVLVLSPLGKDLFHRAISESGVVINTNVGKKNIQAVNEIIATLSQCNDTSSAAMVQCLRQKTESELLEISGKLVQYNISLSTMIDGVVLPKAPEEILAEKSFNTVPYIVGFNKQEFGWIIPMMLQNLLPEGKMNEETASLLLRRFHSELNISESMIPAVIEQYLRGVDDPAKKSELILDMFGDIFFGIPAVLLSRSLRDAGVSTYMYEFRYRPSFVSDKRPQTVEGDHGDEIFFVFGAPLLKEGASEEETNLSKMVMKFWANFARNGNPNGEGLPHWPEYDEQEGYLQIGATTQQAQRLKAEEVAFWTELLAKNPPETDPTEHTEHK
Protein: Antitoxin VapB33 (O50456)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC33.
Interaction partners:
- Ribonuclease VapC33
Sequence:
MRTTLTLDDDVVRLVEDAVHRERRPMKQVINDALRRALAPPVKRQEQYRLEPHESAVRSGLDLAGFNKLADELEDEALLDATRRAR
Protein: At2g26500 (Cytochrome b6f complex subunit (PetM)) (Expressed protein) (O48717)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
- Cytochrome b6-f complex iron-sulfur subunit, chloroplastic
- Cytochrome f
- Cytochrome b6-f complex subunit 6
- Cytochrome b6-f complex subunit 5
- Cytochrome b6-f complex subunit 8
- Cytochrome b
- Plastocyanin major isoform, chloroplastic
- Cytochrome b6-f complex subunit 4
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Cytochrome b6
Sequence:
MATAAAPAVISWTRSGIVSKSGQTQKKSEMKVSYITGLNSYGGLKAQNNKVVSMGSPLCTEQCFANVVMSLKGRRGNGGALSTTCNAVGEIFKIAAIMNALTLVGVAVGFVLLRIETSVEEAEAE
Protein: Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b) (Q62141)
Organism: Mus musculus (Mouse)
Function: Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00810, ECO:0000269|PubMed:20170641, ECO:0000269|PubMed:7889570}.
Interaction partners:
- Histone deacetylase 1
- Sin3 histone deacetylase corepressor complex component SDS3
- Histone deacetylase complex subunit SAP30
- Histone-binding protein RBBP7
- Histone deacetylase 2
- Histone-binding protein RBBP4
- Histone deacetylase complex subunit SAP18
- Paired amphipathic helix protein Sin3a
- PHD finger protein 12
- AT-rich interactive domain-containing protein 4A
Sequence:
MAHAGSGGSAGRGFGGSRWGRSGSGGHEKLPVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLSSQDNSHSHGDCGEDFKQMSYKEDRGQVPLESDSVEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLHTKGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKRSLFTGNGSCEMNSGQKNEEKSLEHNKKRSRPSLLRPVSAPAKKKMKLRGTKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFAQFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKEVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPEDQEKLRLDDCLGGTSEVIQRRAIHRIYGDKAPEVIESLKRNPATAVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIRQLLHRFLPSLFFSQQCPGTSDDSADERDRDRDSAEPERRRPTDEKPPADASPEPPKVLDDVYSLFFANNNWYFFLRLHQTLCARLLKIYRQAQKQLLEHRREQEREQLLCEGRREKAADPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYIGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEQQRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQRRGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGSEGASSSSTEGFLLKPVFLQRNLKKFRRWQCEQVRAMRGEAKSSWKRLMGVESACDVDCRFRLGTHKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHRHFEEWHGRWLEDNVTVAAAGLVQDWLMGEEEEDMVPCKTLCETAHVHGLPVTRYRVQYSRRPASP
Protein: Protein transport protein Sec23A (SEC23-related protein A) (Q7SZE5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex.
Subcellular location: Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000250|UniProtKB:Q15436}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q15436}; Cytoplasmic side {ECO:0000250|UniProtKB:Q15436}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q15436}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q15436}; Cytoplasmic side {ECO:0000250|UniProtKB:Q15436}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q15436}. Note=Enriched at endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). {ECO:0000250|UniProtKB:Q15436}.
Interaction partners:
- Protein SEC13 homolog
- small monomeric GTPase
- Protein transport protein Sec31A
- Protein transport protein Sec31A
- Vesicle-trafficking protein SEC22b-B
- SEC16 homolog B, endoplasmic reticulum export factor.
- Protein transport protein Sec24D
- Protein transport protein Sec24A isoform X2
- Protein transport protein Sec24C
- small monomeric GTPase
Sequence:
MATFQEFIQQNEDRDGVRFSWNVWPSSRLEATRMVVPVASLFTPLKERPDLPPIQYEPVLCSRATCRAVLNPLCQVDYRAKLWACNFCYQRNQFPPTYAGISEVNQPAELLPQFSTIEYVVQRGPQMPLNFLYVVDTCMEDDDLQALKESLQMSLSLLPPTALVGLITFGRMVQVHELGCEGISKSYVFRGTKDLNAKQLQEMLGLTKPAAAQAGRGPQQPQVPPSNRFLQPVQKIDMNLTDLLGELQRDPWPVTQGKRPLRSLGVALSIAVGLLECTFPNTGARIMAFIGGPATQGPGMVVGDELKTPIRSWHDIEKDNAKFMKKATKHYEALANRAAANGHIIDIYACALDQTGLLEMKCCTNYTGGYMVMADSFNTSLFKQTFQRVFTKDVQGCFKMALAGTLEIKTSREIKISGAIGPCVSLNAKGPCVSENEMGTGGTSQWKICGLDPNTTLGFYFEVVNQHNAPIPQGGRGAIQYVTQYQHSSGQRRIRVTTIARNWADAQSQIQSIAASFDQEAAAILMARLAVYKAETEEGPDVLRWLDRQLIRLCQKFGDYHKEDPNSFRFSETFSLYPQFMFHLRRSPFLQVFNNSPDESTYYRHQFMRQDLTQSLIMVQPILYAYSFNGPPEPVLLDSSSILPDRILLMDTFFQILIYHGETVSQWRKAGYQDMPEYENFRHLLQAPVDDAQELLHTRFPMPRYIDTEHGGSQARFLLSKVNPSQTHNNMYAWGQESGAPILTDDVSLQVFMDHLKKLAVSSAA
Protein: Cardiolipin synthase (CMP-forming) (CLS) (EC 2.7.8.41) (Q5U2V5)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q9UJA2}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9UJA2}.
Interaction partners:
- Phosphatidate cytidylyltransferase 2
- Tafazzin family protein
- CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
- Phosphatidate cytidylyltransferase 1
- Lysocardiolipin acyltransferase 1
- Lysophosphatidylcholine acyltransferase 2
- CDP-diacylglycerol--inositol 3-phosphatidyltransferase
- Lysophosphatidylcholine acyltransferase 1
- Lysophosphatidylglycerol acyltransferase 1
- Lysophosphatidylcholine acyltransferase 4
Sequence:
MLAWRVARGAWGSLRVAVRPPGARLGRGGSRRALLPPAACCLGCLAERWRLRPAAFALRLPGTSPRTHCSGAGKAAPEPAAGGDAAAQAPSARWVRASATSSYENPWTIPNLLSMTRIGLAPVLGYLILEEDFNVALGVFALAGLTDLLDGFIARNWANQKSALGSALDPLADKVLISILYISLTYADLIPVPLTYMIISRDVMLIAAVFYVRYRTLPTPRTLAKYFNPCYATARLKPTFISKVNTAVQLILVAASLAAPVFNYADSIYLQILWCCTAFTTAASAYSYYHYGRKTVQVIKGK
Protein: Mannosyl-oligosaccharide glucosidase GCS1 (EC 3.2.1.106) (Alpha-glucosidase 1) (Glucosidase 1) (Protein KNOPF) (Protein MUNCHKIN) (F4HTM3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor. Required for the accumulation of seed storage proteins, the formation of protein bodies, cell differentiation, cellulose biosynthesis and organization (in cell walls), cell shape determination and organization (e.g. epidermal cells), and embryo development. Involved in root development.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:17138701, ECO:0000269|PubMed:19995436}; Single-pass type II membrane protein {ECO:0000269|PubMed:17138701, ECO:0000269|PubMed:19995436}.
Interaction partners:
- Probable glucan 1,3-alpha-glucosidase
- Alpha-glucosidase 2
- Calnexin homolog 2
- Calnexin homolog 1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A
- Dolichol-phosphate mannosyltransferase subunit 1
- Mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS1
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1A
- UDP-glucose:glycoprotein glucosyltransferase
Sequence:
MTGASRRSARGRIKSSSLSPGSDEGSAYPPSIRRGKGKELVSIGAFKTNLKILVGLIILGIIVIYFVINRLVRHGLLFDESQKPRVITPFPAPKVMDLSMFQGEHKESLYWGTYRPHVYFGVRARTPLSLVAGLMWLGVKDEMYVMRHFCENSDDLSTFGWREHNGRDYGRQELVENDMVIETSFVKSKGDGLGYGGDWAVRIDVKNKGLNDDVKRSAHLFFYLADEGGNVLNLGQDGLDFQGSSLLVSGSREDVGDWQIHLKSQNQLETHYSGFKTPHIYNLSDLVQQNLALQARKFGRLQLSDTSEDSSNIYIFQISGRLPFTIDIPFISGIKGESSNVEKRLTSLTGLPLSDLLKKKHQEFDAKFNECFKLSEKHDSETLGVGRTAIANMLGGIGYFYGQSKIYVPKSTQPGSRDNFLLYWPAELYTAVPSRPFFPRGFLWDEGFHQLLIWRWDIRITLDIVGHWLDLLNIDGWIPREQILGAEALSKVPEEFVVQYPSNGNPPTLFLVIRDLIDAIRMEKFVASEKDEVLSFLERASVRLDAWFQWFNTSQKGKEIGSYFWHGRDNTTTQELNPKTLSSGLDDYPRASHPSEDERHVDLRCWMYLAADCMHSITELLGKEDKLSKENYNSTVKLLSNFNLLNQMHYDSDYGAYFDFGNHTEKVKLIWKEVIQENGQLSRQLVRKTFGKPKLKLVPHLGYVSFFPFMSRIIPPDSPILEKQLDLISNRSILWSDYGLVSLAKTSSMYMKRNTEHDAPYWRGPIWMNMNYMILSSLYHYSIVDGPYREKSKAIYTELRSNLIRNVVRNYYETGYIWEQYDQVKGTGKGTRLFTGWSALTLLIMSEDYPIF
Protein: Tigger transposable element-derived protein 5 (Q53EQ6)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MYPAGPPAGPVPRRGRRPLPGPPAPAPAPVPAARPPPPAPGPRPRVAVKMAFRKAYSIKDKLQAIERVKGGERQASVCRDFGVPGGTLRGWLKDEPKLRWFLEQLGGEVGTQRKKMRLANEEEIDRAVYAWFLALRQHGVPLSGPLIQAQAEAFARQIYGPECTFKASHGWFWRWQKRHGISSQRFYGEAGPPAPSPAPGPPVKEEPALPSGAGPLPDRAPAPPPPAEGGYGDEQIYSASVTGLYWKLLPEQAAPPGAGDPGAGGCGRRWRGDRVTVLLAANLTGSHKLKPLVIGRLPDPPSLRHHNQDKFPASYRYSPDAWLSRPLLRGWFFEEFVPGVKRYLRRSCLQQKAVLLVAHPPCPSPAASMPALDSEDAPVRCRPEPLGPPEELQTPDGAVRVLFLSKGSSRAHIPAPLEQGVVAAFKQLYKRELLRLAVSCASGSPLDFMRSFMLKDMLYLAGLSWDLVQAGSIERCWLLGLRAAFEPRPGEDSAGQPAQAEEAAEHSRVLSDLTHLAALAYKCLAPEEVAEWLHLDDDGGPPEGCREEVGPALPPAAPPAPASLPSAMGGGEDEEEATDYGGTSVPTAGEAVRGLETALRWLENQDPREVGPLRLVQLRSLISMARRLGGIGHTPAGPYDGV
Protein: Middle T antigen (MT) (MT-AG) (P0DOJ9)
Organism: Mus musculus polyomavirus 1 (MPyV)
Function: Plays a role in transformation by modulating the activities of cellular proteins involved in control of cell proliferation and by acting as a functional homolog of an activated tyrosine kinase-associated growth-factor receptor. Recruits upon association with host Ppp2/PP2A the Src tyrosine kinase components Src, Yes and Fyn, thereby activating their kinase activity. Activation of Shc1, Pclg1 and p85 mediate signal transduction pathways leading to cell cycle progression and cell division. MT also plays a role in regulation of early and late gene expression and in viral DNA replication.
Subcellular location: Host membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MDRVLSRADKERLLELLKLPRQLWGDFGRMQQAYKQQSLLLHPDKGGSHALMQELNSLWGTFKTEVYNLRMNLGGTGFQVRRLHADGWNLSTKDTFGDRYYQRFCRMPLTCLVNVKYSSCSCILCLLRKQHRELKDKCDARCLVLGECFCLECYMQWFGTPTRDVLNLYADFIASMPIDWLDLDVHSVYNPKRRSEELRRAATVHYTMTTGHSAMEASTSQGNGMISSESGTPATSRRLRLPSLLSNPTYSVMRSHSYPPTRVLQQIHPHILLEEDEILVLLSPMTAYPRTPPELLYPESDQDQLEPLEEEEEEYMPMEDLYLDILPEEQVPQLIPPPIIPRAGLSPWEGLILRDLQRAHFDPILDASQRMRATHRAALRAHSMQRHLRRLGRTLLLVTFLAALLGICLMLFILIKRSRHF
Protein: Nuclear factor of activated T-cells 5, tonicity-responsive (Nuclear factor of activated T-cells 5a) (Q6PD88)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MPSDFISLLSADIDPSSPKSLYSKESVYDLLPAELQLPSLVQQENSSMSQKSGGEAGPPPAAAAAALPTDAAAPCAAASSPGALSSTLPSCPSMLSATSAPEQTPEPQPERMEPASDAAQSQATPSKRRTVLSISPPPEDLLDDSRMSCQDDTLPNLDSEQSSTIWLEDSVSNFSMGSSSSYNDNTEVPRKSRKRTPRQRPGSKPAAREEAGMDVFDADSAKAPHFVLSQLGSDAKVTPKASSLEVSNNQKGGVLSIQYPPKSEGKELKILVQPETQHRARYLTEGSRGSVKDRTQQGFPTIKLDGVSDPVVLQVFVANDAGRVKPHGFYQACRVTGRNTTACKEVDIEGTTVIEVNLEPTNSMTLPVDCVGILKLRNADVEARIGVAGSKKKSTRARLAFRVNIPRPDGSILTLQTLSSPILCTQPAGVPEILKKSLHSGSVAGGEEVFIIGKNFLKGTKVLFQENSSDESGWQAEAEIDMELFHQNHLVVKVPPYHDQTVANPVSVGIAVVTNAGRTHDLQTFTYTPLTEKVEIPVKSELPATVKACTFEEQIKAMQTETSCLNNVIMLPMVKREEPMEVSCNATPSDIFKPVETLSSTQQILEISTVLPSATKSFPSPVALQPVDSQQAPAQIFTTQETLATIQKQDIPSPASFQVSLSEDTTVLQPVPPQVPQQSLRETPETLSPEDSSADGAGMVLVGIDRNPPSQRQQVQALLPQDGVAQLELAVRELQAQQQLNSVLYSPTPSAESLQQHVQENMNSLRLGGNETTLTNQQQQQQEQNILENLQQQQQKALVDLQHQQTVLENLQQHQKVLENLQQHAMGNIQQQQTHKVLENLQHQQQHQRVLENIQQQSSIVTLQHQKVLDNLQQQQQHQINLETLQHQEVLESLKQQLQSELMQTQIPMQCTPSFTNDQQSSTQASTLPQSSDGFLQNPPQQQAALFQQTGGIMTIQTSGFLQQPSAQPSPPQPLFQSHNPLTETQDTQAVLFGATKPPQVQAALFPSTMTMLTSSNLPTEQQPPSASLFIAQSVLPASDNTQNQPPQQITFLTPMQTSGAEPQTVSLFQGQTQLSTPMEQQQSPQQQQMPTSQQAPLFSNITTISPNQAQQPTQTGILFCTTTINPHDLPQALLFSGQNQASLGTDRLPENIFQEQQPMQVVPSSENVSSNNPSNQPAVPAAQAAQNPSIIFTQTGVVNVAQQDSAEPMSFQDQSTGVNESSASLPSTRTELFQDQQPMQVVPSAASVTPVSPSDQPSVNIYLPPSAISALQGGVSAQDLPPAAAAATMFSGQTGVSGLQNAAPTAPPQPSSQLFQTAIGGTLSQPGPPGPAGLFLFEIPSDCGTLINSPGPPLSDQLVTLGHPGADQNQTQLQTNAQIQTLLDPSSNLEDKIDQLLESFQEQGKSLPQDFLDH
Protein: LRR receptor-like serine/threonine-protein kinase HSL2 (EC 2.7.11.1) (Protein HAESA-LIKE2) (C0LGX3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Receptor-like serine/threonine-kinase acting on substrates that controls floral organ abscission. Regulated by the 'INFLORESCENCE DEFICIENT IN ABSCISSION' (IDA) family of ligands.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- Protein IDA-LIKE 1
- ADP-ribosylation factor GTPase-activating protein AGD5
- Protein IDA
- ADP-ribosylation factor GTPase-activating protein
- Polygalacturonase ADPG2
- Protein CLAVATA 3
- Homeobox protein knotted-1-like 6
- Homeobox protein knotted-1-like 2
- Homeobox protein knotted-1-like 1
- Protein IDA-LIKE 4
Sequence:
MLTNTNLFFFLSLLLLSCFLQVSSNGDAEILSRVKKTRLFDPDGNLQDWVITGDNRSPCNWTGITCHIRKGSSLAVTTIDLSGYNISGGFPYGFCRIRTLINITLSQNNLNGTIDSAPLSLCSKLQNLILNQNNFSGKLPEFSPEFRKLRVLELESNLFTGEIPQSYGRLTALQVLNLNGNPLSGIVPAFLGYLTELTRLDLAYISFDPSPIPSTLGNLSNLTDLRLTHSNLVGEIPDSIMNLVLLENLDLAMNSLTGEIPESIGRLESVYQIELYDNRLSGKLPESIGNLTELRNFDVSQNNLTGELPEKIAALQLISFNLNDNFFTGGLPDVVALNPNLVEFKIFNNSFTGTLPRNLGKFSEISEFDVSTNRFSGELPPYLCYRRKLQKIITFSNQLSGEIPESYGDCHSLNYIRMADNKLSGEVPARFWELPLTRLELANNNQLQGSIPPSISKARHLSQLEISANNFSGVIPVKLCDLRDLRVIDLSRNSFLGSIPSCINKLKNLERVEMQENMLDGEIPSSVSSCTELTELNLSNNRLRGGIPPELGDLPVLNYLDLSNNQLTGEIPAELLRLKLNQFNVSDNKLYGKIPSGFQQDIFRPSFLGNPNLCAPNLDPIRPCRSKRETRYILPISILCIVALTGALVWLFIKTKPLFKRKPKRTNKITIFQRVGFTEEDIYPQLTEDNIIGSGGSGLVYRVKLKSGQTLAVKKLWGETGQKTESESVFRSEVETLGRVRHGNIVKLLMCCNGEEFRFLVYEFMENGSLGDVLHSEKEHRAVSPLDWTTRFSIAVGAAQGLSYLHHDSVPPIVHRDVKSNNILLDHEMKPRVADFGLAKPLKREDNDGVSDVSMSCVAGSYGYIAPEYGYTSKVNEKSDVYSFGVVLLELITGKRPNDSSFGENKDIVKFAMEAALCYPSPSAEDGAMNQDSLGNYRDLSKLVDPKMKLSTREYEEIEKVLDVALLCTSSFPINRPTMRKVVELLKEKKSLE
Protein: Odorant receptor 85c (Q9VHQ6)
Organism: Drosophila melanogaster (Fruit fly)
Function: Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates. The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration. May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability.
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Odorant receptor 67b
- Odorant receptor 74a
- Odorant receptor 30a
- Odorant receptor 35a
- Odorant receptor 42a
- Odorant receptor 83a
- Odorant receptor 47a
Sequence:
MKFMKYAVFFYTSVGIEPYTIDSRSKKASLWSHLLFWANVINLSVIVFGEILYLGVAYSDGKFIDAVTVLSYIGFVIVGMSKMFFIWWKKTDLSDLVKELEHIYPNGKAEEEMYRLDRYLRSCSRISITYALLYSVLIWTFNLFSIMQFLVYEKLLKIRVVGQTLPYLMYFPWNWHENWTYYVLLFCQNFAGHTSASGQISTDLLLCAVATQVVMHFDYLARVVEKQVLDRDWSENSRFLAKTVQYHQRILRLMDVLNDIFGIPLLLNFMVSTFVICFVGFQMTVGVPPDIMIKLFLFLFSSLSQVYLICHYGQLIADASSSLSISAYKQNWQNADIRYRRALVFFIARPQRTTYLKATIFMNITRATMTDLLQVSYKFFALLRTMYIK
Protein: protein-serine/threonine phosphatase (EC 3.1.3.16) (F4K802)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MNRLGHKSVVYHGDLRLGELDVNHVSSSHEFRFPNDEIRIHHLSPAGERCPPLAILQTIASFAVRCKLESSAPVKSQELMHLHAVCFHELKTAVVMLGDEEIHLVAMPSKEKKFPCFWCFSVPSGLYDSCLRMLNTRCLSIVFDLDETLIVANTMKSFEDRIEALKSWISREMDPVRINGMSAELKRYMDDRMLLKQYIDNDYAFDNGVLLKAQPEEVRPTSDGQEKVCRPVIRLPEKNTVLTRIKPEIRDTSVLVKLRPAWEELRSYLTAKTRKRFEVYVCTMAERDYALEMWRLLDPEAHLISLKELRDRIVCVKPDAKKSLLSVFNGGICHPKMAMVIDDRMKVWEDKDQPRVHVVSAYLPYYAPQAETALVVPHLCVARNVACNVRGYFFKEFDESLMSSISLVYYEDDVENLPPSPDVSNYVVIEDPGFASNGNINAPPINEGMCGGEVERRLNQAAAADHSTLPATSNAEQKPETPKPQIAVIPNNASTATAAALLPSHKPSLLGAPRRDGFTFSDGGRPLMMRPGVDIRNQNFNQPPILAKIPMQPPSSSMHSPGGWLVDDENRPSFPGRPSGLYPSQFPHGTPGSAPVGPFAHPSHLRSEEVAMDDDLKRQNPSRQTTEGGISQNHLVSNGREHHTDGGKSNGGQSHLFVSALQEIGRRCGSKVEFRTVISTNKELQFSVEVLFTGEKIGIGMAKTKKDAHQQAAENALRSLAEKYVAHVAPLARETEKGPENDNGFLWESSEDVSNKGLEEEAPKENISELVLRK
Protein: L-arabinitol 4-dehydrogenase (LAD) (EC 1.1.1.12) (B6HI95)
Organism: Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) (Penicillium chrysogenum)
Function: Catalyzes the NAD-dependent oxidation of L-arabinitol to L-xylulose in the fungal L-arabinose catabolic pathway. L-arabinose catabolism is important for using plant material as a carbon source. NADP cannot act as a cosubstrate.
Interaction partners:
- D-xylose reductase [NAD
- Phosphotransferase
- Phosphotransferase
- Mannitol 2-dehydrogenase
- Phosphotransferase
- Pc22g22030 protein
- Pc16g10410 protein
- fructan beta-fructosidase
- Pc22g01350 protein
- Pc21g18520 protein
Sequence:
MASATVTKTNIGVYTNPKHDLWIADSSPTAEDINAGKGLKAGEVTIEVRSTGICGSDVHFWHAGCIGPMIVTGDHVLGHESAGQVLAVAPDVTHLKVGDRVAVEPNVICNACEPCLTGRYNGCVNVAFLSTPPVDGLLRRYVNHPAVWCHKIGDMSYEDGAMLEPLSVTLAAIERSGLRLGDPLLITGAGPIGLISLLSARAAGACPIVITDIDEGRLAFAKSLVPEVRTYKVEIGKSAEECADGIINALNDGQGSGPDALRPKLALECTGVESSVNSAIWSVKFGGKVFVIGVGKNEMTIPFMRLSTQEIDLQYQYRYCNTWPRAIRLIQNGVIDLSKLVTHRYSLENALQAFETASNPKTGAIKVQIMSSEEDVKAATAGQKY
Protein: Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2) (P48768)
Organism: Rattus norvegicus (Rat)
Function: Mediates the electrogenic exchange of Ca(2+) against Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to cellular Ca(2+) homeostasis in excitable cells (By similarity). Contributes to the rapid decrease of cytoplasmic Ca(2+) levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory (By similarity). Plays a role in regulating urinary Ca(2+) and Na(+) excretion (By similarity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:16914199, ECO:0000269|PubMed:8021246, ECO:0000269|PubMed:9486131}; Multi-pass membrane protein {ECO:0000305}. Basolateral cell membrane {ECO:0000250|UniProtKB:Q8K596}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8K596}. Perikaryon {ECO:0000269|PubMed:16914199}. Cell projection, dendrite {ECO:0000269|PubMed:16914199}. Cell projection, dendritic spine {ECO:0000269|PubMed:16914199}.
Interaction partners:
- Sodium/calcium exchanger 3
- Sodium/calcium exchanger 1
- cAMP-dependent protein kinase catalytic subunit alpha
- cAMP-dependent protein kinase catalytic subunit beta
- cGMP-dependent protein kinase 2
- Mitochondrial sodium/calcium exchanger protein
Sequence:
MAPLALVGVALLLGAPHCLGEATPTPSLPPPPANDSDASPGGCQGSYRCQPGVLLPVWEPDDPSLGDKAARAVVYFVAMVYMFLGLSIIADRFMASIEVITSKEKEITITKANGETSVGTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFQAGELGPGTIVGSAAFNMFVVIAVCVYVIPAGESRKIKHLRVFFVTASWSIFAYVWLYLILAVFSPGVVQVWEALLTLVFFPVCVVFAWMADKRLLFYKYVYKRYRTDPRSGIIIGAEGDPPKSIELDGTFVGTEVPGELGALGTGPAEARELDASRREVIQILKDLKQKHPDKDLEQLVGIAKYYALLHQQKSRAFYRIQATRLMTGAGNVLRRHAADAARRPGANDGAPDDEDDGASRIFFEPSLYHCLENCGSVLLSVACQGGEGNSTFYVDYRTEDGSAKAGSDYEYSEGTLVFKPGETQKELRIGIIDDDIFEEDEHFFVRLLNLRVGDAQGMFEPDGGGRPKGRLVAPLLATVTILDDDHAGIFSFQDRLLHVSECMGTVDVRVVRSSGARGTVRLPYRTVDGTARGGGVHYEDACGELEFGDDETMKTLQVKIVDDEEYEKKDNFFIELGQPQWLKRGISALLLNQGDGDRKLTAEEEEAQRIAEMGKPVLGENCRLEVIIEESYDFKNTVDKLIKKTNLALVIGTHSWREQFLEAVTVSAGDEEEDEDGSREERLPSCFDYVMHFLTVFWKVLFACLPPTEYCHGWACFGVCILVIGLLTALIGDLASHFGCTVGLKDSVNAVVFVALGTSIPDTFASKVAALQDQCADASIGNVTGSNAVNVFLGLGVAWSVAAVYWAVQGRPFEVRTGTLAFSVTLFTVFAFVGIAVLLYRRRPHIGGELGGPRGPKLATTALFLGLWFLYILFASLEAYCHIRGF