wanglab/gogpt-training-data huggingface dataset:
Protein: RAN binding protein 2 (D4A054)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MRRSKAEVERYIASVQGSAPSPREKSMKGFYFAKLYYEAKEYDLAKKYISTYINVQERDPKAHRFLGLLYEIEENTDKAVECYKRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWVERAAKLFPGSPAIYKLKEQLLDCKGEDGWNKLFDLIQSELYARPDDVHVNIRLVELYRSNKRLKDAVAHCHEADRNMALRSSLEWNSCVVQTLKEYLESLQCLDSDKSTWRATNKDLLLAYSNLMLLTLSTRDVQESRELLESFDSALQSVKSSVGGNDELSATFLETKGHFYMHVGSLLLKMGQQSDIQWRALSELAALCYLIAFQVPRPKVKLIKGETGQNLLEMMAHDRLSQSGHMLLNLSRGKQDFLKEVVESFANKSGQSALCDALFSSQSSKDRSFLGNDDIGNLDGQVPDLDDLARYDTGAVRAHSGSLQHLTWLGLQWNSLPTLPAIRKWLKQLFHHLPQETSRLETNAPESICILDLEVFLLGVIYTSHLQLREKSNSHHTSYQPLCLPLPVCRQLCTERQKSWWDASLICHGTHICKPGTSAKLRLLVQREINSLRGQEKHGLQPALLVHWAQSLQKTGSSLNSFYDQREYIGRSVHYWRKVLPLLKMIRKKNSIPEPIDPLFKHFHSVDIQVSEIGEYEEDAHITFAILDAVNGNIEDAMTAFESIKNVVSYWNLALIFHRKAEDIENDALSPEEQEECKNYLRKTRDYLIKILDDSDSNISVVQKLPVPLESVKEMLNSVMQELEDYSEGGTLYKNGCFRSADSELKHSTPSPTKYSLSPSKSYKYSPKTPPRWAEDQNSLLKMICQQVEAIKKEMQELKLNSNNSASPHRWPAEHYRQDPVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTKGPVYGMNRLPPQQHIYAYSQQMHTPPVQSSSSCMFSQEMYGPPLRFESPATGILSPRGDDYFNYNVQQTSTNPPLPEPGYFTKPPLVAHASRSGESKVIEFGKSNFVQPMQGEVIRPPLATPAHTTQPTPFKFNSNFKSNDGDFTFSSPQVVTQSPSTAYSNSESLLGLLTSDKPLQGDGYSGLKPISAQTGGSRNTFSFGSKSTLTENMGPNQQKNFGFRRSDDMFTFHGPGKSIFTTPTSELANKSHETDGGSAHGDEEDDGPHFEPVVPLPDKIEVKTGEEDEEEFFCNRAKLFRFDGESKEWKERGIGNVKILRHKTSGKIRLLMRREQVLKICANHYISPDMKLTPNAGSDRSFVWHALDYADELPKPEQLAIRFKTPEEAALFKCKFEEAQNILKALGTNASTAANHTLRIVKEPATQDNKDICKSDGGNLNFEFQIVKKEGPFWNCNSCSFKNAATATKCVSCQNTKPTNGKELLGSPLVENGFASKTGPENVQDRFALMTPNKEGHWDCSVCLVRNEPTVSRCIACQNTKSANKNGSSFAQTSFKFGQGDLSKSADSDFRSVFSKKEGQWDCSICLVRNEASSTKCVACQNPAKQAPKEGQWDCSLCSVRNEANAVKCVACQNPVKPSSSTTVTVLPSFKFGTSEMTKPPRSGFEGMFAKKEGQWDCSLCFVRNEASASQCIACQNPNKQNQPTSAVSAPASSETSKSPKCGFEGLFTRKEGEWECTVCSVQNESSSLKCVSCDASKPTHKPIAEAPSAFTVGSKSQLNESAGSQVGTEFKSNFPEKNFKVGISEQKFKFGHVDQEKTPSFTFQGSSNTEFKSIKDGFSFCIPVSADGFKFGIQEKGNQEKKSEKHLENDPGFQAHDTSGQKNGSGVVFGQTSSTFTFADLAKSTSREGFQFGKKDPNFKGFSGAGEKLFSSQSGKVAEKANTSDLEKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEDEKVLYSQRVKLFRFDAEISQWKERGLGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWLASDFSDGDAKLEQLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEMKSGLKDFKTFLTNDQAKVTEEENTSSGADASSASDTTVKQNPDNTGPALEWDNYDLREDALDDSVSSSSVHASPLASSPVRKNLFRFGESTTGFNFSFKSALSPSKSPAKLNQSGTSVGTDEESDVTQEEERDGQYFEPVVPLPDLIEVSSGEENEQVVFSHRAKLYRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMTLQTMKGTERVWVWTACDFADGERKIEHLAVRFKLQDVADSFKKIFDEAKTAQEKDCLITPHVSHLSTPRESPCGKIAIAVLEETTRERTDLTQGDEVVDTTSEAGETSSTSETTPKAVVSPPKFVFGSESVKSIFSSEKSKPFAFGNSSATGSLFGFSFNAPLKNSNSEISSIVQSGSEGKVDPDKGELPPNSDIKQSSDGKVKNLIAFSKETSSTFKTPEKAREKNKPEDPPSDTDILIVYELTPTPEQKALAEKLLLPSTFFCYKNRPGYVSEEEEDDEDFEMAVKKLNGKLYVDDSEKPLEENLADNDKECVIVWEKKPTVEERAKADTLKLPPTFFCGVCSDTDEDNGNGEDFQSELRKVQEAQKSQSEKVTNTVGIEQTGETEATNPDGSKSEEPDSDTKHSSSSPVPGTMDKPVDLSTKKETDMEFPSQGESKTVLFGFGSGTGLSFADLASSNSGDFAFGPKDKNFQWANTGAAVFGTQSTSKDGDDEDGSDEDVVHNEDIHFEPIVSLPEVEVKSGEEDEEVLFKERAKLYRWDRDVSQWKERGIGDIKILWHSVKNYYRILMRRDQVFKVCANHVITKAMELKPLNFSNNALVWTASDYADGEAKIEQLAVRFKTKEITECFKKKIEECQQNIMKLQNGQVSLAAELSKETNPVVFFDVCVDGEPLGRIIMELFSNIVPQTAENFRALCTGEKGFGFKNSIFHRVVPDFICQGGDITKYNGTGGQSIYGDKFDDENFDLKHTGPGLLSMANCGQNTNSSQFFITLKKAEHLDFKHVVFGFVKDGMDTVRKIESFGSPKGSVSRRICITECGQL
Protein: C-C motif chemokine 2 (Immediate-early serum-responsive protein JE) (Monocyte chemoattractant protein 1) (Monocyte chemotactic protein 1) (MCP-1) (Small-inducible cytokine A2) (P14844)
Organism: Rattus norvegicus (Rat)
Function: Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity). Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity). Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-dependent phosphorylation of GRIN2B/NMDAR2B (By similarity).
Subcellular location: Secreted {ECO:0000269|PubMed:23955712}.
Interaction partners:
- Macrophage inflammatory protein-1 alpha receptor
- C-C motif chemokine 7
- C-C chemokine receptor type 5
- C-C chemokine receptor type 3
- C-X-C chemokine receptor type 3
- C-X-C chemokine receptor type 4
- CX3C chemokine receptor 1
- C-X-C chemokine receptor type 2
- C-X-C motif chemokine
- C-C motif chemokine 6
Sequence:
MQVSVTLLGLLFTVAACSIHVLSQPDAVNAPLTCCYSFTGKMIPMSRLENYKRITSSRCPKEAVVFVTKLKREICADPNKEWVQKYIRKLDQNQVRSETTVFYKIASTLRTSAPLNVNLTHKSEANASTLFSTTTSSTSVEVTSMTEN
Protein: Opacity protein opA68 (opA27.5) (Q04881)
Organism: Neisseria gonorrhoeae
Function: Implicated in a number of adherence functions. OPA proteins are implicated in pathogenesis and are subject to phase variation.
Subcellular location: Cell outer membrane.
Interaction partners:
Sequence:
AGEGNGRGPYVQADLAYAYEHITHDYPKPTDPSKGKLSTVSDYFRNIRTHSIHPRVSVGYDFGGWRIAADYARYRKWNDSKYSVSIKNLQRRTSNGNRRDRKTENQENGSFHAVSSLGLSAVYDFKLNDKFKPYIGARVAYGHVRHSIDSTKKITQFLTTAGARGTVSTVHPPYKSTQDAHHQSDSIRRVGLGVIAGVGFGITPKLTLDAGYRYHNWGRLENTRFKTHEASLGVRYRF
Protein: FI21118p1 (Q9VPY4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Uncharacterized protein, isoform F
- ATP-dependent RNA helicase DHX15 homolog
- Uncharacterized protein, isoform D
- ATP-dependent RNA helicase
- Nucleolar protein 6
- RE67794p
- Nucleolar protein 14 homolog
- Bystin
- Nucleolar MIF4G domain-containing protein 1 homolog
- rRNA biogenesis protein RRP36
Sequence:
MDSSSRRSFSGGSENEGGRGSDYYRSRPGSRYSRSRSRSRERNRSHGGIRHRNSRSRSRDRDRSPVFRNDQHRGGRGGAGNGDPDLYHSLINDDYRDQDERNYNSRSNFENRQFRRHDSFDRRHRDRDGESDRELNDYEYEQRSRDLDSRDRSSTDRDWYHNRSRSREHSRPWNRNNNHDDRSRSNERNTRHRDHRMYNGGGSNHNRDRDRDRDREQDRERDRDRDRDRERRGSSDYDSDEGHMRRNKYRSTTEALNIIIIFGLTKEMTRADIMSELIKVNMEPACIRIIRKQGTDSSRGIAFVEFNTVEEAKQWMDITQGVLKLNDERVSMRYSHKRIQDWNCNKCGVCNFKFRFYCFVCKTSREDSETTFSSGSEGVDEVSTILTKKIMLRNLDALTNEEAVLTALQLHLKDLSKTVSKVLISRDSLTQASRGICYLHFDTLVDSMNVHNALTALDPPLTLDDRVVAITYCIDLEEQQALPKNPKELAVKDSTVNSGNISAVSPSGLGGNYTLADVPRLAEYSASLYASNPAEHAYYVQYYTEYYTADINKNNRDSHLTEANSGAAVALSAIQRKQKKMSSIETTITAAATAAAQAAAQVKATLAAQVASAPKGNDGKIYPTPDVTQYQYDETSGYYYDSTTGLYYNAHSQYYYNNETGAYLYWDQRRSTYVLATPASTQAALQEVLADAEQKGEEESKKAKEKEGGNKHDKVKVAKKIVKDMEKWAKQLNQKKDYTAVATPQPILANEVATTSRGNQGGYADVGFSILEKKERGKLNDYAPNPTVGPMNKLVNAYGGTSDSEEDNAASSQNTQSSAVVSGGGGAEESDYVDFHKLTCLLCKRAFQSLEILQKHLKMSTLHKENLAKLNQNTSSSIEEALAYRDRAKERRLKYGESDPPPPNRSRERFEQEIKTLQSRQKQSTSATPAMPISSSNVGSRLLQKMGWSEGQGLGRKNQGRTQIIEADGRSNYVGLGNKSGQMIPGNDYKSYIKKMMKQRYENA
Protein: Uncharacterized WD repeat-containing protein C3D6.12 (P87177)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Probable U3 small nucleolar RNA-associated protein 13
- Periodic tryptophan protein 2 homolog
- Probable U3 small nucleolar RNA-associated protein 18
- U3 small nucleolar RNA-associated protein 21 homolog
- Probable U3 small nucleolar RNA-associated protein 7
- Ribosome biogenesis protein bms1
- U3 small nucleolar RNA-associated protein 6
- U3 small nucleolar RNA-associated protein 20
- U3 small nucleolar RNA-associated protein 15
- U3 small nucleolar RNA-associated protein 10
Sequence:
MVKSYTRYEPTEFFGVIASSGCNILGQPSSSAKSVGRAIVGGLESVLEWDLKTGQLLSKWKDSDCSAKVTCIANFDEMYAVGYADGSIRLWKDGELLITLNGHKSAVTTMDFDKMGTRLASGSMDTDIIVWDIVAETGLFRLRGHKDQITKLLFITPPSKNTAEETVVDTDIDSGDMDVDSKSSDSFLLSVGKDSFMKLWDLSIQHCVETHVDHQGEIWAMCVSPDAKRCLTAGTGSDVKVWEISFPDDNNFTPTTKAFQQLGTFTRQSRDRPITLAYDVSNRYVVFQAHDRLLEVFRLRSSAELEKILNRRRRRKKSEDVSITLKDEYEPFALIRTTARASSVAWIPGNRTPTLVTSLQNNSIEVYALDVKSEGSAAPLTERASRISAIEIPGHRADVRTLALSANHDVILSGANGSLKLWNKKTTSCIRTIECGYVLAASFINNDKCIVSAYKSGELEVYDIASSSLIERIQAHDGAIWDLAVGHDGTYFATASADHTVKLWSLKSSFDFVPGTTRKVTTLKLEQTRQIDFTDDVLAVKISPDGRFVAASLLDNTVKVYYLDSLKFFLNLYGHKLPVLSMDISYDSKLLVTCSADKNVKIWGLDFGDCHKSIFAHQDSIMEVTFQPDTYNFFTCSKDREVRYWDGKSFDLILKLRGHHSEVWALAVGPTFVVSGSHDHSIRLWEQGDDLVFLEEERERELEEQYESTLVSSYENAEADGEVKDGDVAAVTKQTIESLKDGEKILEAITIGIEDLDQEIQYRLDLLKSPGKARGPRNPILAHLGVSAEEYVLNTFKKIRSSHLDDALLVLPFEHVLSLFRFIDIWASRKWSIPLVSRIIFFLLRTYHRQLTTTVKMRPLLNNIRSSLRGSLQEERSLIGYNAAGLSYLRHEWELTHNTSLEDIDSTSLEVDGKKRAFSNIV
Protein: Tsr1p (Q5A346)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
- Serine/threonine-protein kinase RIO2
- 20S-pre-rRNA D-site endonuclease NOB1
- Ltv1p
- SnoRNA-binding rRNA-processing protein
- mRNA-binding protein
- rRNA adenine N
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein eS6
- Small ribosomal subunit protein eS7
- Small ribosomal subunit protein uS4
Sequence:
MANSHRNTLKHDHKPFKSKHATKGQIKARIKGKVEKSSNSSGGSKSSKVVSKLERKNLSKQQRDNKILETKLTKKLFEGNSGAEKIVTIITLTNDLSAVDIANRLFNEQEDTSNESITRFDFGYPSVTNINIAKFKTNLKVIIPKQNNMISILDAAQVSDFVLLGISATEEIGENSFGETVLRALIAQGISTTIGVLPNIVSAYPKRNLQLDVKQSLQSFYHHFFPSRDGSSNRGSGTDSGGNKLYSLELDSDNSNCLRIICQKFPQSITWRDSRGWLVADKVEIFNPNGMPVENQQQMMVVEGMVRGVGFNVNRLVHLPGLGDFQLHKLEKLARKARGNSSRNHRGGMDIDTGNDGDAEETFLPNEQQESLDELNPDEGIDMGTMEDDDDFLNNDNFGVRSEGKIYFDNGNSNGTSSSSTGKKLVPRGTSEYQGRWFVDDVLDEDASDLEEQREGEGEEEEDANIVDDDMMVEDNMEADDITDSIHDSEMMHVDLSPEEESRQLEEYRSLAKDDLEFPDEIELHPNESAIERLKGFRGVKSLGNCDWDYDEYDPEAPSILKRLFQVSNYKATKNKVNKQFIKQTEITAGNRVRLYIIIPPGASNNVSSVIGSCSSVPFPVYELLEHEHKLGVCNFSFEAWQDYEKPIINKEQIIVQYGPRRQIIQPLYNQANNNPNNVHKLENFVHHNQGGGGAIIATAITPVLFTNSPTLFFKIHPDADDSSNSNGGSVEFVGKGTYLGSDAKRIMVQRVVLTGHPIKIHKRVVTIRYMFFNREDINYFKAVSLFTKNSGRVGFIKESLGTHGYFKANFDGKLTSQDVVAMSLYKRSWPEVSTAWNKFNY
Protein: Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va) (Q4VBU7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004443, ECO:0000256|RuleBase:RU368103}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004443, ECO:0000256|RuleBase:RU368103}; Matrix side {ECO:0000256|ARBA:ARBA00004443, ECO:0000256|RuleBase:RU368103}.
Interaction partners:
- Cytochrome c oxidase subunit 7C, mitochondrial
- Cytochrome c oxidase subunit 6C
- Cytochrome b-c1 complex subunit 8
- Zgc:86599.
- Cytochrome c oxidase subunit
- Cytochrome c oxidase subunit 4
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Cytochrome c oxidase subunit 2
- Cytochrome c oxidase subunit 3
- Cytochrome b-c1 complex subunit 7
Sequence:
MFRAALRLSFSGARSLARSRPQYTASVAARSYSHGKQETDEEFDARWVTYFSKPDIDAWELRKGMNTLIGYDLVPEPKILDAALRACRRLDDLASAIRILEAVKDKAGPHKEIYPYVIQELRPTLDELGIATPEELGIDKA
Protein: POU domain, class 6, transcription factor 1 (Brain-specific homeobox/POU domain protein 5) (Brain-5) (Brn-5) (mPOU homeobox protein) (Q14863)
Organism: Homo sapiens (Human)
Function: Transcription factor that binds preferentially to a variant of the octamer motif (5'-ATGATAAT-3').
Subcellular location: Nucleus.
Interaction partners:
Sequence:
MPGISSQILTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTVSQLVSKPHTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSKLNVFQIP
Protein: High-affinity nitrate transporter 2.1 (AtNRT2:1) (Protein ACH1) (Protein LATERAL ROOT INITIATION 1) (O82811)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in nitrate transport, but does not seem to be able to mediate transport by its own. Acts as a dual component transporter with NTR3.1. Acts as a repressor of lateral root initiation under high sucrose/low nitrate conditions.
Subcellular location: Cell membrane {ECO:0000269|PubMed:17573350, ECO:0000269|PubMed:17583518, ECO:0000269|PubMed:19704673, ECO:0000269|PubMed:20561257}; Multi-pass membrane protein {ECO:0000269|PubMed:17573350, ECO:0000269|PubMed:17583518, ECO:0000269|PubMed:19704673, ECO:0000269|PubMed:20561257}.
Interaction partners:
- Nitrate reductase 1
- Nitrate reductase 2
- Ferredoxin--nitrite reductase, chloroplastic
- High-affinity nitrate transporter 3.1
- Protein NRT1/ PTR FAMILY 6.3
- Protein NLP7
- CBL-interacting serine/threonine-protein kinase 23
- Protein NRT1/ PTR FAMILY 7.3
- Protein NRT1/ PTR FAMILY 4.6
- Ammonium transporter 2
Sequence:
MGDSTGEPGSSMHGVTGREQSFAFSVQSPIVHTDKTAKFDLPVDTEHKATVFKLFSFAKPHMRTFHLSWISFSTCFVSTFAAAPLVPIIRENLNLTKQDIGNAGVASVSGSIFSRLVMGAVCDLLGPRYGCAFLVMLSAPTVFSMSFVSDAAGFITVRFMIGFCLATFVSCQYWMSTMFNSQIIGLVNGTAAGWGNMGGGITQLLMPIVYEIIRRCGSTAFTAWRIAFFVPGWLHIIMGILVLNLGQDLPDGNRATLEKAGEVAKDKFGKILWYAVTNYRTWIFVLLYGYSMGVELSTDNVIAEYFFDRFHLKLHTAGLIAACFGMANFFARPAGGYASDFAAKYFGMRGRLWTLWIIQTAGGLFCVWLGRANTLVTAVVAMVLFSMGAQAACGATFAIVPFVSRRALGIISGLTGAGGNFGSGLTQLLFFSTSHFTTEQGLTWMGVMIVACTLPVTLVHFPQWGSMFLPPSTDPVKGTEAHYYGSEWNEQEKQKNMHQGSLRFAENAKSEGGRRVRSAATPPENTPNNV
Protein: Zinc finger protein 423 (F5H7S1)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTYCSRLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTRHPQLSEKADLQCIHCPEVFVDENTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSNHSVSPDPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRGQKKMRDDGQGWTKVVYSCPYCSKRDFNSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTLYNLNEHVRKLHKNHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPSDGNNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSAKLESPVVQPTQSFMEVYSCPYCTNSPIFGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSASANSISNGEYPCNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYVCESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCTACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHSKKYNCKFCSKAFHAIILLEKHLREKHCVFDAATENGTANGVPPMATKKAEPADLQGMLLKNPEAPNSHEASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCNVCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRICKMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAASSPNGQGLQKLYKCALCLKEFRSKQDLVKLDVNGLPYGLCAGCMARSANGQVGGLAPPEPADRPCAGLRCPECSVKFESAEDLESHMQVDHRDLTPETSGPRKGTQTSPVPRKKTYQCIKCQMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPVCFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNHTMSQHAQ
Protein: Antimicrobial peptide GP-19 (B3A0L2)
Organism: Xenorhabdus budapestensis
Function: Has antimicrobial activity against P.wickerhamii and against Gram-positive bacteria B.subtilis and B.megaterium as well as Gram-negative bacteria X.campestris and P.solanacearum. The synthetic peptide partially inihibts growth of fungi P.capsici, V.dahliae, F.graminearum and F.omysporum.
Subcellular location: Secreted {ECO:0000269|PubMed:22497806}.
Interaction partners:
Sequence:
GPVGLLSSPGSLPPVGGAP
Protein: LD38742p (Spt7) (Q9VX12)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Protein will decrease acetylation
- SAGA-associated factor 29kDa
- SAGA complex subunit Spt20
- SAGA factor-like TAF6
- Transcriptional adapter 1-2
- Transcriptional adapter 2b
- SAGA complex subunit Spt3
- Transcriptional adaptor 3, isoform C
- SAGA-associated factor 11 homolog
- tRNA
Sequence:
MQTEHWGSLPAEDDGGQLTPDKYVPTAAKKLKLDEIRQRGDPQPQEKHHKLELRSALVTQTIEVMKQTEVLQSLIETYSNKNGSSNYLLNPCLMIPEVDFPPENAAELVGSQKFQKPIWFTPTVDTAYSRGDPEAYPEIPSSACRQAMRKVMCGMLRLAGFTDCSESAVQLLTDATEEFLRSFIGEYRGYYDSQPRLQNSTVLQLVPLERAHFAQTGTSLTQVHNYYKHKVLARNRAEIAEFNSVLQEYDKLMKESQSSMQKQHNEFNGHDFLNILDNSATGSSQSIGGMAMGDMLQDLGGSTGSSGTVSSQQMLYGLLDGQISSNTSNMTGTSGNGSTGGNGNGNGATISNFHATFET
Protein: Transcription factor MYB60 (Myb domain protein 60) (VvMYB60) (B3VTV7)
Organism: Vitis vinifera (Grape)
Function: Transcription factor involved in the regulation of gene (e.g. drought-regulated and flavonoid biosynthetic genes) expression and stomatal movements leading to negative regulation of responses to drought and responses to other physiological stimuli (e.g. light).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
Interaction partners:
Sequence:
MGRPPCCDKVGIKKGPWTPEEDIILVSYIQEHGPGNWRSVPTNTGLLRCSKSCRLRWTNYLRPGIKRGNFTPHEEGMIIHLQALLGNKWAAIASYLPQRTDNDIKNYWNTHLKKKIKKFQSALSPHMASDSTTSTCTNHQFVPRSYAGDDHHRRGSSFEVINGHSSAHPSLNSPISTYASSTENISRLLEGWMRSSPKATKEKLHQNSSLEEGSIDMTGNSMAVAAVTSVQCYRPKLEQGGGELVANDEFESILEYENLNDDHHQTTDATIPSDDHDHDHEMKMDHDQKKHNPPLSFLEKWLLDESAAQGEEMMDQLSPIF
Protein: U-box domain-containing protein 10 (EC 2.3.2.27) (Plant U-box protein 10) (RING-type E3 ubiquitin transferase PUB10) (Q9C9A6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Functions as an E3 ubiquitin ligase.
Interaction partners:
- Transcription factor MYC2
- ARM repeat superfamily protein
- ARM repeat superfamily protein
- ARM repeat superfamily protein
- ARM repeat superfamily protein
- SCY1-like protein 2 B
- SCY1-like protein 2 A
- Ubiquitin C-terminal hydrolase 13
- Ubiquitin C-terminal hydrolase 12
- Protein ROH1D
Sequence:
MAGGAITPDSLIGLIAEINEIPGNFGLFKKDCSDLARRVGLLTHLIEEIRDSSPPSESDASSSLNSHECDWWSDLVVGLQAAKRLLSSATSFQARESSDGAAKRISFQFQCVTWKLEKALGDLTYDRYDISDEVREQVELARLQLRRAMQRYGSLNSKKFSSGLSEPMEKDASSNRKVIEKLESIPETVHSLSDEKKFESPPPWKSSSVSLAFFLSKDGDDERLEKAVTENSDDSQKSDNLTIPEDFLCPISLELMKDPAIVSTGQTYERSFIQRWIDCGNLSCPKTQQKLENFTLTPNYVLRSLISQWCTKHNIEQPGGYMNGRTKNSDGSFRDLSGDMSAIRALVCKLSSQSIEDRRTAVSEIRSLSKRSTDNRILIAEAGAIPVLVKLLTSDGDTETQENAVTCILNLSIYEHNKELIMLAGAVTSIVLVLRAGSMEARENAAATLFSLSLADENKIIIGASGAIMALVDLLQYGSVRGKKDAATALFNLCIYQGNKGRAVRAGIVKPLVKMLTDSSSERMADEALTILSVLASNQVAKTAILRANAIPPLIDCLQKDQPRNRENAAAILLCLCKRDTEKLISIGRLGAVVPLMELSRDGTERAKRKANSLLELLRKSSRKLGSL
Protein: Calsequestrin-2 (Calsequestrin, cardiac muscle isoform) (P51868)
Organism: Rattus norvegicus (Rat)
Function: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2; this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats (By similarity).
Subcellular location: Sarcoplasmic reticulum lumen {ECO:0000250|UniProtKB:O09161}. Note=This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of cardiac and slow skeletal muscle cells. {ECO:0000250|UniProtKB:O09161}.
Interaction partners:
- Triadin
- Ryanodine receptor 2
- Inositol 1,4,5-trisphosphate/ryanodine receptor domain-containing protein
- Junctophilin-2
- Calsequestrin-1
- Ryanodine receptor 1
- Junctophilin
- Junctophilin
- Voltage-dependent L-type calcium channel subunit alpha-1C
- Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
Sequence:
MKRIYLLVVGLYLLSFSRAEEGLNFPTYDGKDRVVSLSEKNLKQVLKRYDLLCLYYHEPVSSDKVAQKQFQLKEIVLELVAQVLEHKNIGFVMVDSRKEAKLAKRLGFSEEGSLYVLKGGRTIEFDGEFAADVLVEFLLDLIEDPVEIVNNKLEVQAFERIEDQIKLLGFFKNEDSEYYKAFQEAAEHFQPYIKFFATFDKGVAKKLSLKMNEVGFYEPFMDEPSVIPNKPYTEEELVEFVKEHQRPTLRPLRPEDMFETWEDDLNGIHIVAFAEKSDPDGYEFLEILKQVARDNTDNPDLSILWIDPDDFPLLVAYWEKTFKIDLFKPQIGVVNVTDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDNEDEDDDGDNDNDDDDDDDDNSDEDNDDSDDDDDDDE
Protein: Chromo domain-containing protein (Q54RN0)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- RNA helicase
- Origin recognition complex subunit 2
- DNA
- Histone H3.3 type a
- Histone H3.3 type c
- Histone H3.3 type b
Sequence:
MGKRDKRIIEEPEEPEEAGDVFEVEKILDKRVQHGRIQYSIRWKGFTADYDTWEDEDNVAGCPELVKEFESSREQEKKKSRKRKNVIVNDDQTAVESSSPPPTTKPSSSSSSTKTTKAATSTTTNTSTQQKTNHLIDDEEYIKNEYIKFGVPYIEGIGFENGHCVEEIIGCKPFGQDNTLFFFVKWRGQEKLSWVLNEILKHKEPLQLIEFYENRLKFGYKGQQS
Protein: AP-2 complex subunit alpha-2 (Adaptor protein complex AP-2 subunit alpha-2) (Adaptor-related protein complex 2 subunit alpha-2) (Alpha-adaptin 2) (Clathrin assembly protein complex 2 alpha-C large chain) (At-aC-Ad) (At-alphaC-Ad) (Q8LPK4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Subunit of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The complex binds polyphosphoinositides.
Subcellular location: Membrane, coated pit {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles in the plasma membrane. {ECO:0000250}.
Interaction partners:
- AP-2 complex subunit mu
- AP-2 complex subunit sigma
- Beta-adaptin-like protein B
- Clathrin heavy chain 1
- Calcium sensing receptor, chloroplastic
- Beta-adaptin-like protein C
- AP-5 complex subunit mu
- Clathrin heavy chain 2
- Beta-adaptin-like protein A
- Clathrin interactor EPSIN 2
Sequence:
MTGMRGLSVFISDVRNCQNKEAERLRVDKELGNIRTCFKNEKVLTPYKKKKYVWKMLYIHMLGYDVDFGHMEAVSLISAPKYPEKQVGYIVTSCLLNENHDFLKLAINTVRNDIIGRNETFQCLALTLVGNIGGRDFAESLAPDVQKLLISSSCRPLVRKKAALCLLRLFRKNPDAVNVDGWADRMAQLLDERDLGVLTSSTSLLVALVSNNHEAYSSCLPKCVKILERLARNQDVPQEYTYYGIPSPWLQVKAMRALQYFPTIEDPSTRKALFEVLQRILMGTDVVKNVNKNNASHAVLFEALSLVMHLDAEKEMMSQCVALLGKFISVREPNIRYLGLENMTRMLMVTDVQDIIKKHQSQIITSLKDPDISIRRRALDLLYGMCDVSNAKDIVEELLQYLSTAEFSMREELSLKAAILAEKFAPDLSWYVDVILQLIDKAGDFVSDDIWFRVVQFVTNNEDLQPYAASKAREYMDKIAIHETMVKVSAYILGEYGHLLARQPGCSASELFSILHEKLPTVSTPTIPILLSTYAKLLMHAQPPDPELQKKVWAVFKKYESCIDVEIQQRAVEYFELSKKGPAFMDVLAEMPKFPERQSSLIKKAENVEDTADQSAIKLRAQQQPSNAIVLADPQPVNGAPPPLKVPILSGSTDPESVARSLSHPNGTLSNIDPQTPSPDLLSDLLGPLAIEAPPGAVSYEQHGPVGAEGVPDEIDGSAIVPVEEQTNTVELIGNIAERFHALCLKDSGVLYEDPHIQIGIKAEWRGHHGRLVLFMGNKNTSPLTSVQALILPPAHLRLDLSPVPDTIPPRAQVQSPLEVMNIRPSRDVAVLDFSYKFGTNVVSAKLRIPATLNKFLQPLQLTSEEFFPQWRAISGPPLKLQEVVRGVRPLALPEMANLFNSFHVTICPGLDPNPNNLVASTTFYSETTGAMLCLARIETDPADRTQLRLTVGSGDPTLTFELKEFIKEQLITIPMGSRALVPAAGPAPSPAVQPPSPAALADDPGAMLAGLL
Protein: Nuclear envelope integral membrane protein 1 (O14524)
Organism: Homo sapiens (Human)
Function: Together with EMD, contributes to nuclear envelope stiffness in germ cells. Required for female fertility (By similarity).
Subcellular location: Nucleus inner membrane {ECO:0000250|UniProtKB:Q6ZQE4}; Multi-pass membrane protein {ECO:0000255}; Nucleoplasmic side {ECO:0000250|UniProtKB:B9X187}. Nucleus envelope {ECO:0000250|UniProtKB:Q6ZQE4}. Note=Colocalizes with lamins and RAN-GTP at the nuclear envelope. {ECO:0000250|UniProtKB:Q6ZQE4}.
Interaction partners:
- Ran GTPase-activating protein 1
- E3 SUMO-protein ligase RanBP2
- SUMO-conjugating enzyme UBC9
- RANBP2-like and GRIP domain-containing protein 2
- GTP-binding nuclear protein Ran
Sequence:
MAGGMKVAVSPAVGPGPWGSGVGGGGTVRLLLILSGCLVYGTAETDVNVVMLQESQVCEKRASQQFCYTNVLIPKWHDIWTRIQIRVNSSRLVRVTQVENEEKLKELEQFSIWNFFSSFLKEKLNDTYVNVGLYSTKTCLKVEIIEKDTKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTGMTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQEIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPHIALAIIIIALCTKNLEHPIQWLYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALEELREFCNSPDCSAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIYEEASSEEEDSYSRCPAITQNNFLT
Protein: Dynein assembly factor with WD repeat domains 1 (D3Z7A5)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm, cytoskeleton, flagellum basal body {ECO:0000250|UniProtKB:Q3Y8L7}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q3Y8L7}. Note=Expression is concentrated at the flagellum basal body but is also detected along the length of the flagellum. {ECO:0000250|UniProtKB:Q3Y8L7}.
Interaction partners:
Sequence:
MKLKSLLLRYYPPGIMLEYEKGGELKTKSIDLLELSPSTDVNTLVGEIQQAEPLITASRTKQVRLLVQRLQEKLRQHSDHNFYLFKVLRAHILPLTNVALNKAGSCFITGSYDRTCKVWDTASGEELHTLEGHKNVVYAIAFNNPYGDKIATGSFDKTCKLWSAETGKCYHTFRGHTAEIVCLSFNPQSTVVATGSMDTTAKLWDIQNGEEVVTLTGHLAEIISLSFDTSGDRIITGSFDHTVVVWDASTGRKVHTLIGHCAEISSALFNWDCSLILTGSMDKTCMLWDATSGKYVATLTGHDDEILDSCFDYTGKLIATASADGTARVYNATTRKCVTKLEGHEGEISKISFNPQGNRLLTGSSDKTARIWDVQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNSCRIWR