wanglab/gogpt-training-data huggingface dataset:
Protein: Pipsqueak, isoform A (A1Z8A4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00320}.
Interaction partners:
Sequence:
MAAVRGHQYFSLRWNNYQNTMTSVFQQLREDLSFVDVTLSCEHGSLKAHKVVLSACSTYFQKLLLENPCKHPTIILPADIIFTDLKTIIDFVYRGEIDVTESELQGLLRTAEQLKIKGLCETAENADDLNDAATATITVSENIQQAVVGNIVNAAIVPGAPSPSLEQQQQHHQQQQQQQAQEQHQQQQVHAQQQQQQQQQINAALLTQHGVSSGSVSLSGQLLSSSASGSSGSLAGGQQASQTPSGLQPTPRKSRLKRSKSPDLSSGGGAGSSGGSSSGSTQQQPQPAHHHHPQTILIQGQNPNSIVSLQQTADGNYIPVSGSGDDSDAEDHEHEHNHGHGHGHGGHTHGHGHSHEHSHDHEHEHKPNKICKTEHSVASPASNSSSASNNAAGVSGVTSTGQAIVTQIVVARDGKDTKNMTSLGMGMNGGLLGVPMGFLDFTPEPPAPSATPVTVTEHVDLSCNPSTDTRDLSNTTEPLDIDNHLAQQIHRLDQSPMHSISHHHTGDESNSNLVQHIKSEVIEAKHLAAQHHALSQAQQQHAHHQAHQQHQQHQQQQHQQQQQHLHAQQLLAQSQLQQQQQQQQQQQQHHQQQQQQAAAAAAAAGVHGQHGGHVTHADIGGATVMEIDPSQIKHEPGMIITPEIVNMMSSGHMDMYNSDTSEDSMMIANGSPHDQKEPHYTNLDQQHGLGGSVCGPGPGGAGGGGGMSGGAGSGSGEKDALKNQNMSLTKASAIYGIPSTTLWQRAHRMGIETPKKEGGTKSWNEDALQNALEALRSGQISANKASKAFGIPSSTLYKIARREGIRLAAPFNAAPTTWTPEDLERALEAIRAGNTSVQKASAEFGIPTGTLYGRCKREGIELSRSNPTPWSEDAMNEALNSVRVGQMSINQAAIHYNLPYSSLYGRFKRGKYDVVANTSGVALLNTSGNTTGSIEIIEHSQENSLHMLQQQFPYSPSPHPPTPQHHSTPQHHSSAQQGPPTPQHMQQHVVHMQQQQQQQQQQSPHPGHHPQHMQQDVVTSSSQVVHSQQQQQLQQIYQHHGTPERS
Protein: Tat pathway signal protein (O25542)
Organism: Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Interaction partners:
- Catalase
Sequence:
MKRRDFIKTTTLGATGAVLGAQILQAEESKGSVAKYKIEAQYSIDFDSAEHTSLFIPMPSVVASNVHLQGNHASYKSMLNFGVPYLQVDFLKSTQKKQVHLSYEIASYQLNERLFETSDFVAMGRYERDDASVANIANQLKGTTPKESVRNFYAFIKHEMPKRQKALEGKENLPKRESLPWFATISKESMFVSLCHACGIKSAEVQGLKLGQNSVVKNAPRVEVYLKDSFLAFDFQNNHKEVFIPLNRHKDMQLDSALLATFGDAFALVDGRDLGNYESKLFEKRVSYTIV
Protein: Ras-related protein RABA1b (AtRABA1b) (Ras-related protein Rab11) (AtRab11) (Q39222)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Intracellular vesicle trafficking and protein transport.
Subcellular location: Cell membrane {ECO:0000269|PubMed:15060130}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Trafficking protein particle complex II-specific subunit 120 homolog
- Exocyst complex component SEC6
- Exocyst complex component SEC8
- ARF guanine-nucleotide exchange factor GNL1
- ADP-ribosylation factor GTPase-activating protein AGD3
- V-type proton ATPase subunit a1
- ADP-ribosylation factor 1
- Kinesin-like protein KIN-14E
- Geranylgeranyl transferase type-2 subunit beta 1
- Vacuolar protein sorting-associated protein 9A
Sequence:
MAGYRVEDDYDYLFKVVLIGDSGVGKSNLLSRFTKNEFNLESKSTIGVEFATRTLKVDGKVVKAQIWDTAGQERYRAITSAYYRGAVGALLVYDVTRRATFENVDRWLKELKNHTDPNIVVMLVGNKSDLRHLLAVPTEDGKSYAEQESLCFMETSALEATNVEDAFAEVLTQIYRITSKKQVEAGEDGNASVPKGEKIEVKNDVSALKKLGCCSN
Protein: Chromosome associated protein H2, isoform E (Q8INL2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Condensin-2 complex subunit
- Structural maintenance of chromosomes protein
- Structural maintenance of chromosomes protein
- Chromosome associated protein G, isoform F
- Condensin complex subunit 2
- Condensin complex subunit 1
Sequence:
MERILPEEAEAAYLSEAREQILEIAKNRPGTQVAKCIRAYDEQQDLASLVVLLEELSKNTDYSTDLRISLGYYIEELLRHCLGRNDVSRRSAIVAAGSALQYCGKIYGDRVEYLCQVVEHQIEALLTSELQKETPSGSAAPEKNERRPEETRKRHPKKLTNKEVDPYLLTLEPKRFKTMSDDKRFNAAGFVKCTRNRTIEYLYQDHTPPNLWKHAPIVDPHNPYDQDEKKQYKMFTYHVEHRYNTLLPDIPFERLNLIKEYVHTNQVNTTEILNEHMTTKEYLDEYIALENQMLAARYGAIVTRRRRLVDSARFMEDNLDEGLAKKMCMDKNLPMDTNETVLIDQSLVDENSRSLTTAESTMGISQAENSTLKSSEVEATLSVSHIENSLSDSQEENPPLSSTLAINESSVLDSTRVDPIKDLTLDELLLIDSGISMEELSDIQMHTAGQSFDDEGVVLSDLEDQRQLSPMLQMVSPSMEAKTLNIIEMDADLIMNVPREVSYPILLNVMGLPIKRLRRKCIFKLPPEFDLFRQARLPIKREGQQKSPTTPRTVLQIGREAPQNEREPGSPCSLEFDEDLNFLGFRQRRPTFDSGFDIEEPRVSSCVSTIGEVKTELEDEIEANTNNLTDASASDALNENVNDTKESGLGDSLAQELNASTEPNAENNTANSSQLEVTATESSGTLSGLETTVDLGMESALVSSVLDLSTEPSAMDSNIINVTQPDNSDLEISTVQDQDTLHDEADANDLSAETPNPIADSAVDDCSLIRDWHRRLAPALEAAHERQNFNIKDLGTEILDICKAGNRTATLADVMADKDPSIMCRYMLASLVLTNHGNVSLDFENRDKSKPIDMSQFRMHLKSMKRMEINPEDDVGNINAAQSKSTPRSKQLNDSAHKPRTSTTASAPTKRKSAENSLSEVFAKTVRLIQPIPKMWPTPSDADSGISSMGSSLASTARLK
Protein: Zinc finger CCCH-type containing 12D (B7ZBA4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEHPSKMEFFQKLGYDREDVLRVLGKLGEGALVNDVLQELIRTGSRPGALEHPAAPRLVPRGSCGVPDSAQRGPGTALEEDFRTLASSLRPIVIDGSNVAMSHGNKETFSCRGIKLAVDWFRDRGHTYIKVFVPSWRKDPPRADTPIRGIGMGNEWRSILLGAAARE
Protein: Penta-EF hand domain-containing protein 2 (Apoptosis-linked gene 2 protein homolog B) (Dd-ALG-2b) (DdPEF-2) (Q95YL4)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11481037, ECO:0000269|PubMed:11927596}. Membrane {ECO:0000269|PubMed:11481037, ECO:0000269|PubMed:11927596}; Peripheral membrane protein. Note=Membrane-associated in the presence of Ca(2+). {ECO:0000269|PubMed:11481037}.
Interaction partners:
- Putative calpain-like cysteine protease A
- Uncharacterized protein
- ESCRT-I complex subunit tsg101
Sequence:
MYGYGYTPAVVAPTVMSFSFVPPQAFQQCWFYSLYTQIQQAQLYEMQSWFMRVDANRSGTISSGELQYLNIGGTPLGIETATKLIKVFDHNKNGQIDFYEYAALHQFINNLYRCFVANDRNFSGTIDANEIYNALITSGFQLPFPTVNYLFLKLSPSGYGLLFTQFLNLCATVALTRSLFEWNDPMRTGVVHLNLAQLYDIIALV
Protein: Peripherin-2 (Retinal degeneration slow protein) (Tetraspanin-22) (Tspan-22) (P23942)
Organism: Homo sapiens (Human)
Function: Essential for retina photoreceptor outer segment disk morphogenesis, may also play a role with ROM1 in the maintenance of outer segment disk structure (By similarity). Required for the maintenance of retinal outer nuclear layer thickness (By similarity). Required for the correct development and organization of the photoreceptor inner segment (By similarity).
Subcellular location: Membrane {ECO:0000250|UniProtKB:P17810}; Multi-pass membrane protein {ECO:0000255}. Cell projection, cilium, photoreceptor outer segment {ECO:0000250|UniProtKB:P15499}. Photoreceptor inner segment {ECO:0000250|UniProtKB:P15499}.
Interaction partners:
- Rod outer segment membrane protein 1
- Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
- Rhodopsin
- Retinal guanylyl cyclase 1
- Protein RD3
- Retinal-specific phospholipid-transporting ATPase ABCA4
- Interphotoreceptor matrix proteoglycan 1
- Bestrophin-1
- Very long chain fatty acid elongase 4
- Cyclic nucleotide-gated channel beta-1
Sequence:
MALLKVKFDQKKRVKLAQGLWLMNWFSVLAGIIIFSLGLFLKIELRKRSDVMNNSESHFVPNSLIGMGVLSCVFNSLAGKICYDALDPAKYARWKPWLKPYLAICVLFNIILFLVALCCFLLRGSLENTLGQGLKNGMKYYRDTDTPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEIQWISNRYLDFSSKEVKDRIKSNVDGRYLVDGVPFSCCNPSSPRPCIQYQITNNSAHYSYDHQTEELNLWVRGCRAALLSYYSSLMNSMGVVTLLIWLFEVTITIGLRYLQTSLDGVSNPEESESESQGWLLERSVPETWKAFLESVKKLGKGNQVEAEGADAGQAPEAG
Protein: BOS complex subunit TMEM147 (Protein NIFIE 14) (Transmembrane protein 147) (Q9BVK8)
Organism: Homo sapiens (Human)
Function: Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes. The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions. Also acts as a negative regulator of CHRM3 function, most likely by interfering with its trafficking to the cell membrane. Negatively regulates CHRM3-mediated calcium mobilization and activation of RPS6KA1/p90RSK activity. Regulates LBR localization to the nucleus inner membrane.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:20538592, ECO:0000269|PubMed:21056967, ECO:0000269|PubMed:32694168, ECO:0000269|PubMed:36044892, ECO:0000269|PubMed:36261522}; Multi-pass membrane protein {ECO:0000255}. Nucleus membrane {ECO:0000269|PubMed:32694168}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:I6VSD2}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- BOS complex subunit NCLN
- BOS complex subunit NOMO2
- PAT complex subunit CCDC47
- Calcium load-activated calcium channel
- Protein transport protein Sec61 subunit alpha isoform 1
- Protein transport protein Sec61 subunit beta
- Large ribosomal subunit protein eL32
- Large ribosomal subunit protein eL22
- Large ribosomal subunit protein eL38
- Large ribosomal subunit protein uL2
Sequence:
MTLFHFGNCFALAYFPYFITYKCSGLSEYNAFWKCVQAGVTYLFVQLCKMLFLATFFPTWEGGIYDFIGEFMKASVDVADLIGLNLVMSRNAGKGEYKIMVAALGWATAELIMSRCIPLWVGARGIEFDWKYIQMSIDSNISLVHYIVASAQVWMITRYDLYHTFRPAVLLLMFLSVYKAFVMETFVHLCSLGSWAALLARAVVTGLLALSTLALYVAVVNVHS
Protein: LIM domain-containing protein (Q8INQ9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Ras suppressor protein 1
- Integrin linked kinase, isoform A
- GH23568p
- Rhea, isoform B
- Vinculin
- Paxillin, isoform F
- Unc-112-related protein
- Integrin beta-PS
- Fermitin 2
- Dreadlocks, isoform B
Sequence:
MMYSKAEVVQAANMSLGAMHCTRCADGFEPTEKIVNSNGELWHTQCFVCAQCFRPFQDGIFYEFEGRKYCERDFHVLFAPCCNKCGEFVIGRVIKAMSASWHPQCFRCQLCAKELADCGFIKNQNRALCHECNAKVKAEITGRYVCQKCHGLIDEEPLRFRGEVYHGYHFSCTACGTELDSTAREVKSRPGLAANDMNELYCLRCHDKMGIPICGACRRPIEERVVTALGKHWHVEHFVCAKCEKPFLGHRHYEKRGLAYCETHYHQLFGNLCFVCNQVIGGDVFTALNKAWCVHHFACSVCDTKMTQKSKFYEYDEKPVCKKCYDRFPNELRRRLRTAHEMTMKKNT
Protein: Zinc finger protein 41 (P51814)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- tRNA
- Serine/threonine-protein kinase A-Raf
- Zinc finger protein 385B
- Zinc finger protein 510
- Transcription intermediary factor 1-beta
- Zinc finger protein 75D
Sequence:
MAANGDSPPWSPALAAEGRGSSCEVRRERTPEARIHSVKRYPDLSPGPKGRSSADHAALNSIVSLQASVSFEDVTVDFSKEEWQHLDPAQRRLYWDVTLENYSHLLSVGYQIPKSEAAFKLEQGEGPWMLEGEAPHQSCSGEAIGKMQQQGIPGGIFFHCERFDQPIGEDSLCSILEELWQDNDQLEQRQENQNNLLSHVKVLIKERGYEHKNIEKIIHVTTKLVPSIKRLHNCDTILKHTLNSHNHNRNSATKNLGKIFGNGNNFPHSPSSTKNENAKTGANSCEHDHYEKHLSHKQAPTHHQKIHPEEKLYVCTECVMGFTQKSHLFEHQRIHAGEKSRECDKSNKVFPQKPQVDVHPSVYTGEKPYLCTQCGKVFTLKSNLITHQKIHTGQKPYKCSECGKAFFQRSDLFRHLRIHTGEKPYECSECGKGFSQNSDLSIHQKTHTGEKHYECNECGKAFTRKSALRMHQRIHTGEKPYVCADCGKAFIQKSHFNTHQRIHTGEKPYECSDCGKSFTKKSQLHVHQRIHTGEKPYICTECGKVFTHRTNLTTHQKTHTGEKPYMCAECGKAFTDQSNLIKHQKTHTGEKPYKCNGCGKAFIWKSRLKIHQKSHIGERHYECKDCGKAFIQKSTLSVHQRIHTGEKPYVCPECGKAFIQKSHFIAHHRIHTGEKPYECSDCGKCFTKKSQLRVHQKIHTGEKPNICAECGKAFTDRSNLITHQKIHTREKPYECGDCGKTFTWKSRLNIHQKSHTGERHYECSKCGKAFIQKATLSMHQIIHTGKKPYACTECQKAFTDRSNLIKHQKMHSGEKRYKASD
Protein: T-complex protein 1 subunit zeta (TCP-1-zeta) (CCT-zeta) (O94515)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- T-complex protein 1 subunit epsilon
- T-complex protein 1 subunit delta
- Probable T-complex protein 1 subunit beta
- T-complex protein 1 subunit alpha
- T-complex protein 1 subunit gamma
- Probable T-complex protein 1 subunit theta
- Probable T-complex protein 1 subunit eta
- Ribosome-associated molecular chaperone sks2
- Phosducin-like protein C2A9.09
- Probable prefoldin subunit 5
Sequence:
MLSLLNPKAESIQRAQALQVNISAAIGLQDVLKSNLGPTGTTKMLVDGAGAIKLTKDGKVLLTEMQIQNPTASCIAKAATAQDDATGDGTTSVCLLVGELLKQAELYIREGLHPSLISDGFNLAKNEALTFLDSFKTDFEVDREVLLNVAKTSLSTKISSKVVESLAPAVVDAILTIRRPDEPIDLHMVEIMKMQNRSASDTQLIRGLLLDHGARHPDMPKQVKNAYILILNVSLEYEKSEINSGFFYSTSEQRERLVESERKFVDNKLRKIVELKKEVCERDPTANFVIINQKGIDPLSLDVLAKNGIMALRRAKRRNMERLQLACGGVAQNSVDDLNPEVLGWAGSVYERTLGEEKYTFVEDVKDPKSATILIHGPNTYTIQQIQDATRDGLRAVKNAVEDNCLIVGAGAFEVACAAHLRNKFAAKEVKGKAKMGVYAYADALLIIPKTLAANSSYDTQDAIVALQEEASEGYKVGLDLKTGMPFDPEVEGIYDNYRVIRHMLHSATVIASNLISVDQILRAGRSSLKEGPPQ
Protein: Glucocorticoid receptor (Nuclear receptor subfamily 3 group C member 1) (Q6RKQ3)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm, cytoskeleton, spindle {ECO:0000256|ARBA:ARBA00004186}. Mitochondrion {ECO:0000256|ARBA:ARBA00004173}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU004334}.
Interaction partners:
Sequence:
MDSLIGDSDPNLFPMSMRTETAFSRDQNPMDMDQEGYIGKDQKLFSDNTLDLLQDFELTGSPSDFYVGDDAFLSSLADDTLLGDESQDRGVSNSTSKPAATMTNSGSFSGSNTTTLNGSSLLACQDESNSSTSMTTTATFPMVKMEKESGFIQLCTPGVIKQENTSAMRSSSCQMSGSTGGSTSSSPSELSSSSPSPISICGVSTSGGQSYHFGGNSSINTTLASTTSGASQQKDQKPSVFSLYPPLVTVGEAWNNISYGDGASGMQGLSSPTSAFSSSYASSTSKLGGGAASCTTQGKAGTTHKVCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGTGARGQHNYLCAGRNDCIIDKIRRKNCPACRFRKCLLAGMNLEARKTKKLNRLKGVQQPTTAELTPRPLPEARSLVPKSMPQLTPTMLSLLKAIEPDTIYSGYDGTLPDTSTRIMTTLNRLGGRQVVSAVKWAKALPGFRNLHLDDQMTLLQCSWLFLMSFGLGWRSYQQCDGNMLCFAPDLVINQDRMKLPYMADQCEQMLKISSEFVRLQVSHDEYLCMKVLLLLSTVPKDGLKSQAVFDEIRMSYIKELGKAIVKREENSSQNWQRFYQLTKLLDSMHEMVGGLLDFCFYTFVNKSLSVEFPEMLAEIISNQLPKFKAGSVKPLLFHQK
Protein: rRNA-processing protein fyv7 (O14276)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in the processing of the 20S pre-rRNA.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Nucleolar protein 16
- Ribosomal RNA-processing protein 1 homolog
- Splicing factor YJU2
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1
- Potassium transport protein 2
- Uncharacterized hydrolase C215.10
- rRNA biogenesis protein rrp36
- DNA-directed RNA polymerase I subunit rpa14
Sequence:
MANHSSSSSDQGTKKKGFKFRQLPEHAYQGKAKRIKQDLILKAKTKKHFYKNVRPEEYIKKGSGERKRKFSKKSHLQELYERSEEKRRIQQEKEDAKVQKRLEIEKKQKDREQTRNMLSKKTKRGQPIMRNQINHLLAKVKQTS
Protein: (thale cress) hypothetical protein (A0A178WDD2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MEFSTSKRPATTATAAESVHFRLLCPATRTGAIIGKGGSVIRHLQSVTGSKIRVIDDIPVPSEERVVLIIAPSGKKKDESNVCDSENPGSEEPKQEKGSECAGTSGGDDEEAPSSAQMALLRVFERIVFGDDAATVDGDELDKGESEGLCRMIVRGNQVDYLMSKGGKMIQKIREDSGAIVRISSTDQIPPCAFPGDVVIQMNGKFSSVKKALLLVTNCLQESGAPPTWDECPFPQPGYPPEYHSMEYHPQWDHPPPNPMPEDVGPFNRPVVEEEVAFRLLCPADKVGSLIGKGGAVVRALQNESGASIKVSDPTHDSEERIIVISARENLERRHSLAQDGVMRVHNRIVEIGFEPSAAVVARLLVHSPYIGRLLGKGGHLISEMRRATGASIRVFAKDQATKYESQHDEIVQVIGNLKTVQDALFQILCRLREAMFPGRLPFQGMGGPPPPFMGPYPEPPPPFGPRQYPASPDRYHSPVGPFHERHCHGPGFDRPPGPGFDRPPSPMSWTPQPGIDGHPGGMVPPDVNHGFALRNEPIGSENPVMTSANVEIVIPQAYLGHVYGENCSNLNYIKQVSGANVVVHDPKAGTTEGLVVVSGTSDQAHFAQSLLHAFILCGQS
Protein: NCK adaptor protein 1 (C9JVV5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAEEVVVVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERKNSARKASIVKNLKDTLGIGKVKRKPSVPDSASPADDSFVDPGERLYDLNMPAYVKFNYMAEREDELSLIK
Protein: ATP sulfurylase/APS kinase isoform SK2 (EC 2.7.1.25, EC 2.7.7.4) (Q9UIR2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVMESGDWLVGGDLQVLEKIRWNDGLDQYRLTPLELKQKCKEMNADAVFAFQLRNPVHNGHALLMQDTRRRLLERGYKHPVLLLHPLGGWTKDDDVPLDWRMKQHAAVLEEGVLDPKSTIVAIFPSPMLYAGPTEVQWHCRSRMIAGANFYIVGRDPAGMPHPETKKDLYEPTHGGKVLSMAPGLTSVEIIPFRVAAYNKAKKAMDFYDPASSLLPPCNRHNEFDFISGTRMRKLAREGENPPDGFMAPKAWKVLTDYYRSLEKN
Protein: Sporulation-specific protein 5 (Meiotic RNA-binding protein 1) (Meiotically up-regulated gene 12 protein) (Q2L4W6)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: RNA-binding protein which plays a role in sporulation. Regulates the progression of meiosis I and may function in the vicinity of the Mei2 dot.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372, ECO:0000269|PubMed:16896214}.
Interaction partners:
- Meiosis-specific transcription factor mei4
- Meiotic recombination protein rec8
- RNA binding exosome specificity factor Mmi1
- Cell cycle protein kinase spo4
- Meiosis protein mei2
- Sporulation-specific protein 6
- NURS complex subunit red1
Sequence:
MNGIITPQKQKQLMSSPSRDPLSTTELSTPTSQTTVDVNDTKKSEGLDSTIILLTPGTSPNATPGSSELGLSKKPNSIKNNTYSTAAQAAYLNRRAADQSTVMTTDPISYANNNINNGTLPQQNAYYANSYYPSYYAQSQAISNNRPGVSGFRPAFNSVAPCYGSQWQTHQSVHPYHVNNTHQYLKPYVQNVYPQMPSLNQPGLHIVNQPTYLAPVPSATVPTNSVSLSMPSFSQGQKNIPAAINQEMSVGTTKENTNYLSQLVGLHPAIPPAIPSMFPMSHDNKKSNMESTSRTRNVYIRGLPPNTSDENLLLYTNRFGKVSSSKAIIDMETNLCKGYGFACFEEEKSALICISAMTLCGYQCSFAKESFSARLQSLQDTESTNLYISNLPLHWNESDISTLFKPSKIISNRVLRDSKEQSRGVGFARMQDRKTAEDIINKFNNFVLDPALPPLQIRFADSTDQKKFKGQTQKRRLWRAREYSVLTKGMTANNAFSKVEEFANNSMPSKVGMYVPLESNTVYQHSPTYDTYGWQSMYPSYSVYPSNYENSRSTTPYHAHPATSAAN
Protein: Peroxisome proliferator-activated receptor delta (PPAR-delta) (NUCI) (Nuclear hormone receptor 1) (NUC1) (Nuclear receptor subfamily 1 group C member 2) (Peroxisome proliferator-activated receptor beta) (PPAR-beta) (Q03181)
Organism: Homo sapiens (Human)
Function: Ligand-activated transcription factor key mediator of energy metabolism in adipose tissues. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.
Subcellular location: Nucleus {ECO:0000269|PubMed:35675826}.
Interaction partners:
- Retinoic acid receptor RXR-alpha
- Fatty acid-binding protein 5
- Nuclear receptor corepressor 1
- Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
- Retinoic acid receptor RXR-beta
- Nuclear receptor corepressor 2
- Retinoic acid receptor RXR-gamma
- Peroxisome proliferator-activated receptor alpha
- Nuclear receptor coactivator 1
- Platelet glycoprotein 4
Sequence:
MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY
Protein: GDSL esterase/lipase At5g55050 (EC 3.1.1.-) (Extracellular lipase At5g55050) (Q9FIA1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Dirigent protein 21
- Putative F-box protein At2g33655
- Lecithin-cholesterol acyltransferase-like 1
- Protein PHOTOPERIODIC CONTROL OF HYPOCOTYL 1
- glucan endo-1,3-beta-D-glucosidase
- Ureide permease 2
- F-box protein At1g11270
Sequence:
MPTNNTPFLTIFLLFLGLLRFDSFPGLEAATGKLASIPGLYVFGDSLVDAGNNNYLPISISKANYPHNGVDFPNKKPTGRFCNGKNAADAIAEKFGLPLPPPYLSLRGLLKREKRKSAAVTGVNFASGGAGIFNSSDQKLGQAIPLSKQVNNWLSIHEEVMKLEPSAAQLHLSKSLFTVVIGSNDLFDYFGSFKLRRQSNPQQYTQLMADKLKEQLKRIHDSGARRFLIIGVAQIGCTPGKRAKNSTLHECDEGANMWCSLYNEALVKMLQQLKQELQGSITYTYFDNYKSLHDIISNPARYGFADVTSACCGNGELNADLPCLPLAKLCSDRTKHLFWDRYGHPTEAAARTIVDLMLTDDTHYSSPITLTQLVST
Protein: Interleukin-18 (IL-18) (Q8QFQ8)
Organism: Gallus gallus (Chicken)
Function: Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q14116}. Secreted {ECO:0000250|UniProtKB:Q14116}. Note=The precursor is cytosolic. In response to inflammasome-activating signals, cleaved and secreted. Mature form is secreted and released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. In contrast, the precursor form is not released, due to the presence of an acidic region that is proteolytically removed by CASP1 during maturation. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10. {ECO:0000250|UniProtKB:Q14116}.
Interaction partners:
- Uncharacterized protein
- Interleukin 18 receptor accessory protein.
- Interleukin-1
- Interleukin-6
- Interleukin-10
- Uncharacterized protein.
- Transcription factor Jun
- Transcription factor p65
- Nuclear factor NF-kappa-B p105 subunit
- Interferon gamma
Sequence:
MSCEEIAVCAVRLRENLCLYFEELECDAFCKDKTIKRFFRNVNSQLLVVRPDLNVAAFEDVTDQEVKSGSGMYFDIHCYKTTAPSARMPVAFSVQVEDKSYYMCCEKEHGKMVVRFREGEVPKDIPGESNIIFFKKTFTSCSSKAFKFEYSLEQGMFLAFEEEDSLRKLILKKLPREDEVDETTKFVTSHNERHNL
Protein: Protocadherin 1 (Q2TJH4)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MGPLRPSPGPGGQRLLLPPLLLALLLLLAPSASHTTQVVYKVPEEQPPNTLIGSLAADYGLPDVGHLYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQIPGNPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSDQGANA
Protein: Vesicular glutamate transporter, isoform A (Vesicular glutamate transporter, isoform B) (Q9VQC0)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Synaptotagmin 1
- Ras-related protein Rab-3
- Glutamate decarboxylase
- Vesicular inhibitory amino acid transporter
- Bruchpilot, isoform J
- Glutamate receptor IIC
- Vesicular acetylcholine transporter
- GH10249p
- Neuronal synaptobrevin, isoform J
- MIP05841p)
Sequence:
MKGLTAFKEKATGVFGGLKPNMEKFEISQSYHGGHGGYEEMEGGDREGRGPGGGHAYDDDDDRPDSPASFEEIERPPLRKIDKYCKAECPCMPARYTIATMACVGFMIAFGMRCNMSAAKLKGEHNGTVFMNWTVAVESHVDSSFFWGYLVTQIPGGFIASKFPANKIFGLSIVSSATLHLFVPFAMTLMHGHVVICVRVLQGLFEGVTYPACHGIWRFWAPPMERSRLATLAFSGSYAGVVVGLPLSGLLADAVGYQAPFYAYGVFGIIWYMFWIWLCFENPRKHPAISIPELKYIEKSLGESAHPTMPSLKTTPWREMMRSMPVYAIIVANFCRSWNFYLLVLFQSSFLKHKFGFKVEEAGFVGSLPHLIMTTIVPFGGMLADHLRKNGILSTTNVRKLFNCGGFGMEGLFFLFVAHSSTATGAMFALTCGVAFSGFAISGYNVNHLDIAPRYASILMGLSNGIGTLAGIIVPYALDGLIQANPTGCWTTVFTLAACVHLVGCTFYGIFASGELQPWAEPPAEEQKVWAPPPGAITNTDPSQAGMLGDYMKETSFGAPEYTEQSQMQQSTAISYGATGHVANNPFAMASGAPPIAEEDAPPTYGDVTNPGQYGYTQGQMPSYDPQGYQQQ
Protein: PH-sensitive chloride channel 1, isoform N (M9PI70)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MGCVFEAAKEQPHKPRSRQLRRNQCRGKAEKAAAGTRGKVAVRGNNDKPAEDIKIKDNYQQNHKTQTETQTEVAAVVAIATDAGAETETETEAEAQKEPATGPEHLKAAAQVLLTIRQARQENNKHSSSQVAETHKDEGEDALARQGSIVDTAAGRIGIDIAATTIQVAERHEDGQHWQQHNVRRRRRQPDPAAHPASITKLSAISLHFHALAALAKTLQKHEDLSPVQDRQPLAYRAWQEHPYAETQMPATMSAAIIANVGATAAATSAAAFQYLGQHYKHYSQSISFYAASSVLLMLCYLTTASTAAATQSETGALDKHPIHGIDWSKFDESSSDKEILDLLLEKKRYDKRLLPPVNDEDFCCGLQSPDMATNQNARRPHNRGTLTVNVNVLLLSLASPDESSLKYEVEFLLNQQWNDPRLQYGNKSHYDFLNALHHHDSIWTPDTYFIMHGDFKDPIIPMHFALRIFRNGTITYAMRRHLILSCQGSLHIFPFDDPKCSFSMESISYEEAQIKYVWKNDEDTLRKSPSLTTLNAYLIKNQTTACDQNSWRGNYSCLQVELTFTRDRAYYFTTVFIPGIILVTSSFITFWLEWNAVPARVMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRKRPLHNVVYRPGENPVTQRLPAVLSRIGVILASPLASAAATPAMSMMGGATPMSSGTPAASSSVATPGTPRITDPEEFFGGGMRWQEAHGGIIGAAVQNLRARSIKRKAARSPSTSISPHPSGRPTEHIYEEPGGSTSGVTSTKVKFKDELKEEQPEEAESSTKLRRSVATSTPALVVRIEAEIDPEAEDKPIQDMEMTERQLSLPLKPPRRKASRSNSPASVYSDAFENVEATPGEKRQNAGAPNEIVACTTCGGSNSPCTHSANNGCATETCFVQVRKKEPPHPIRVAKTIDVIARITFPTAYAIFLIFFFVHYKGFS
Protein: Mce-family protein Mce3D (O53970)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Mce-family protein Mce3F
- Mce-family protein Mce3A
- Conserved hypothetical integral membrane protein YrbE3B
- Probable conserved Mce associated membrane protein
- Conserved hypothetical integral membrane protein YrbE3A
- Possible Mce-family lipoprotein LprM
- Mce-family protein Mce3C
- Mce-family protein Mce3B
- Probable conserved membrane protein
- Outer membrane protein Rv1973
Sequence:
MTTKLRRARSVLATALVLVAGVILAMRTADAAARTTVVAYFDNSNGVFAGDDVLIRGVPVGKIVKIEPQPLRAKISFWFDRKYRVPADAAAAILSPQLVTGRAIQLTPPYAGGPTMADGTVIPQERTVVPVEWDDLRAQLQRLTALLQPTRPGGVSTLGALINTAADNLRGQGATIRDTIIKLSQAISALGDHSKDIFSTVTNLSTLVTALHDSADLLERLNHNLAAVTSLLADGPDKIGQAAEDLNAVVADVGSFAAEHREAIGTASDKLASITTALVDSLDDIKQTLHISPTVLQNFNNIFEPANGALTGALAGNNMANPIAFLCGAIQAASRLGGEQAAKLCVQYLAPIVKNRQYNYPPLGANLFVGAQARPNEVTYSEDWLRPDYVAPVADTPPDPAAAVTVDPATGLRGMMMPPGGGS