wanglab/gogpt-training-data huggingface dataset:
Protein: cDNA FLJ12737 fis, clone NT2RP2000337 (Q9H9I0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MDQCYFENSLSTECIIRSASRSDGCQMPKLFCQNLPPPLPPKKYAITSVPQSEKSESTPGVKLTEVFKATSHLPKHSLSTASEPSLEVSTHMNDERHKETFQVRECFGNTPNCPSSSSTNDFQANSGAIDAFCQPELDSISTCPNETVSLTTYFSVDSCMTDTYRLKYHQRPKLSFPESSGFCNNSLS
Protein: Nucleophosmin/nucleoplasmin 2 (A0A8I5YBJ6)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSRHSTSSMTETTAKNMLWGSELTQEKQTCTFRAQGERKDSCKLLLSTICLGEKAKEEVNRVEILPQEDRKSPITVATLKASVLPMVTVTGIELSPPVTFRLRAGSGPVFLSGQECYETSDMAWEDDEEEEEEEEEDEDEDEDADLSLEEIPIKQVKRAAPQRPTSIAKVGETALLPTLSLFLSRPSPQDKSPWKKGKSTPKPKRSTSKK
Protein: Proteasome subunit beta type-5 (EC 3.4.25.1) (A0A140VJS7)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP
Protein: ATP synthase subunit C lysine N-methyltransferase (EC 2.1.1.-) (Q9XX11)
Organism: Caenorhabditis elegans
Function: Mitochondrial protein-lysine N-methyltransferase that trimethylates ATP synthase subunit C. Trimethylation is required for proper incorporation of the C subunit into the ATP synthase complex and mitochondrial respiration.
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q6P4H8}.
Interaction partners:
- Xenotropic and polytropic retrovirus receptor 1 homolog
Sequence:
MGMNTGLVIAGVAGATALAISAAAIPFVAPALRRVCIPYVPATTEQLANVSRALSLATSSNSNKKGTLIDLGSGDGRVVLQCAREGFNSTGVELNSILVAYSKYRSIREGLGKETRFMRKNIFKTDLNPYQTAVIFGAESLMGDLVPKLSEMRSNTNLLACRFPLPENDAWKLEHQIGEGIDAVWVYKRN
Protein: Light-harvesting complex stress-related protein 3.1, chloroplastic (Chlorophyll a-b binding protein LHCSR3.1) (P0DO19)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Function: Required for non-photochemical quenching (NPQ), a mechanism that converts and dissipates the harmful excess absorbed light energy into heat and protect the photosynthetic apparatus from photo-oxidative damage. NPQ includes dissipating excess light energy to heat (qE) and the reversible coupling of LHCII to photosystems (state transitions or qT), which are considered separate NPQ mechanisms. Is responsible for most of the excess light energy to heat dissipation (qE), also known as energy-dependent chlorophyll fluorescence quenching activity of chlorophyll excited states. Involved in a de-coupling and re-coupling of energy transfer to photosystem II (PSII) during qT. Binds chlorophyll a and b. Is able to sense luminal acidification of the thylakoid membranes, which occurs along with elevated electron flow caused by excess light. Establishes interactions with photosystem II (PSII) antenna components upon lumen acidification, and protonation of lumen-exposed, negatively charged residues both in LHCSR3 and in PSII antenna components. Mediates excitation energy transfer from light-harvesting complex II (LHCII) to photosystem I (PSI), rather than photosystem II (PSII), at low pH, which mimics the acidified lumen of the thylakoid membranes in high light-exposed chloroplasts. Activates PSI-dependent fluorescence quenching in addition to dissipating excitation energy in LHCII to avoid photooxidative stress under excess light. Contributes with PGRL1 to the regulation of electron flow upstream of photosystem I (PSI), and limits the accumulation of electrons on the PSI acceptor side, thus avoiding PSI photoinhibition.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Photosystem II protein PSBS1
- Photosystem II protein PSBS2
- Chlorophyll a-b binding protein
- Uncharacterized protein
- Phototropin
- Chlorophyll a-b binding protein
- Photosystem I P700 chlorophyll a apoprotein A1
Sequence:
MLANVVSRKASGLRQTPARATVAVKSVSGRRTTAAEPQTAAPVAAEDVFAYTKNLPGVTAPFEGVFDPAGFLATASIKDVRRWRESEITHGRVAMLAALGFVVGEQLQDFPLFFNWDGRVSGPAIYHFQQIGQGFWEPLLIAIGVAESYRVAVGWATPTGTGFNSLKDDYEPGDLGFDPLGLKPTDPEELKVMQTKELNNGRLAMIAIAAFVAQELVEQTEIFEHLALRFEKEAILELDDIERDLGLPVTPLPDNLKSL
Protein: Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (P62046)
Organism: Mus musculus (Mouse)
Function: Acts as a negative regulator of GTPase CDC42 by sequestering CDC42-guanine exchange factor DOCK8. Probably by preventing CDC42 activation, negatively regulates CD4(+) T-cell migration in response to chemokine stimulation.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q9Y2L9}.
Interaction partners:
- Dedicator of cytokinesis protein 8
- Dedicator of cytokinesis protein 6
Sequence:
MATPGSEPQAFAPALSVTALHPHLHQHHQHHQHHQHHGGTGGTGFNLPLNRGLERALEEAANSGGLNLSARKLKEFPRTTAPGHDLSDTVRADLSKNRLVEVPMELCQFVSLEILNLYHNCIRVIPEAIVNLQMLTHLNLSRNQLSALPACLCGLPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRELNVRRNYLKVLPPELVDLPLVKFDFSCNKVLVIPVCFREMKQLQVLLLENNPLQSPPAQICTKGKVHIFKYLSIQACQIKTSDSLYLPTIERPHLHQHVEDSKKDSDSGVGSDNGDKRLSATEPSDEDTVSLNAPMSNIVEEDQTIKEDACHRLTPTKGEFQPKPSILGDSGISGQEREQLAGRADARHSGLMNYIKDQAEDCEELLRIEEDAHWHMEELLNSSKDRELDIAMIEQLREAELLQDPNGLSADIIERSILNLFPMDSGEASEFPDPSLNGQLQLETSPDREVQNDLMLQSNGSQYSPNEIRENSPSVSPTANITAPFGLKPRSGSWCPEEVQGSLQAESSPRRPQLLSRHVFLRPQRNLESIDPQFTIRRKMEQMREEKELVEQLRESIEMRLKVTLHEDLGAALMDGVVLCHLANHVRPRSVASIHVPSPAVPKLSMAKCRRNVENFLEACRKLGVPEEKLCLPHHILEEKGLVKVGTTVQALLDVTVTKALFT
Protein: L-type lectin-domain containing receptor kinase S.6 (LecRK-S.6) (EC 2.7.11.1) (Q9FHX3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in resistance response to the pathogenic oomycetes Phytophthora infestans and Phytophthora capsici and to the pathogenic bacteria Pseudomonas syringae.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9LSR8}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MNHHHYSLVIFHLILFLSLDFPTLSHRFSPPLQNLTLYGDAFFRDRTISLTQQQPCFPSVTTPPSKPSSSGIGRALYVYPIKFLEPSTNTTASFSCRFSFSIIASPSCPFGDGFAFLITSNADSFVFSNGFLGLPNPDDSFIAVEFDTRFDPVHGDINDNHVGIDVSSIFSVSSVDAISKGFDLKSGKKMMAWIEYSDVLKLIRVWVGYSRVKPTSPVLSTQIDLSGKVKEYMHVGFSASNAGIGSALHIVERWKFRTFGSHSDAIQEEEEEKDEECLVCSGEVSENPKEIHRKGFNFRVTVVGLKIPVWSLLPGLAAIVILVAFIVFSLICGKKRISEEADSNSGLVRMPGRLSLAEIKSATSGFNENAIVGQGASATVYRGSIPSIGSVAVKRFDREHWPQCNRNPFTTEFTTMTGYLRHKNLVQFQGWCSEGTETALVFEYLPNGSLSEFLHKKPSSDPSEEIIVLSWKQRVNIILGVASALTYLHEECERQIIHRDVKTCNIMLDAEFNAKLGDFGLAEIYEHSALLAGRAATLPAGTMGYLAPEYVYTGVPSEKTDVYSFGVVVLEVCTGRRPVGDDGAVLVDLMWSHWETGKVLDGADIMLREEFDAEEMERVLMVGMVCAHPDSEKRPRVKDAVRIIRGEAPLPVLPARRPLLRIRPANEAEEMIVDGLVGEDLPWMTPKSHFS
Protein: Large ribosomal subunit protein uL24m (39S ribosomal protein L24, mitochondrial) (L24mt) (MRP-L24) (Q96A35)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:25278503, ECO:0000269|PubMed:25838379, ECO:0000269|PubMed:28892042}.
Interaction partners:
- Large ribosomal subunit protein uL13m
- Large ribosomal subunit protein bL21m
- Large ribosomal subunit protein bL17m
- Large ribosomal subunit protein uL29m
- Large ribosomal subunit protein bL9m
- Large ribosomal subunit protein uL11m
- Large ribosomal subunit protein uL4m
- Large ribosomal subunit protein bL19m
- Ubiquitin-like protein FUBI
- Large ribosomal subunit protein uL3m
Sequence:
MRLSALLALASKVTLPPHYRYGMSPPGSVADKRKNPPWIRRRPVVVEPISDEDWYLFCGDTVEILEGKDAGKQGKVVQVIRQRNWVVVGGLNTHYRYIGKTMDYRGTMIPSEAPLLHRQVKLVDPMDRKPTEIEWRFTEAGERVRVSTRSGRIIPKPEFPRADGIVPETWIDGPKDTSVEDALERTYVPCLKTLQEEVMEAMGIKETRKYKKVYWY
Protein: cAMP-dependent protein kinase regulatory subunit (P30625)
Organism: Caenorhabditis elegans
Function: Controls the rhythmic contraction of enteric muscles probably by regulating G-protein coupled receptor aex-2-mediated calcium influx in GABAergic DVB neurons.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:2303451}.
Interaction partners:
- cAMP-dependent protein kinase catalytic subunit
- cAMP-dependent protein kinase, catalytic subunit-like
- Regulator of G-protein signaling rgs-5
- Serine/threonine-protein kinase sgk-1
- Non-specific serine/threonine protein kinase
- Ribosomal protein S6 kinase beta
- Probable 3',5'-cyclic-AMP phosphodiesterase pde-4
- Serine/threonine-protein kinase akt-2
- Protein kinase domain-containing protein
- Guanine nucleotide-binding protein G
Sequence:
MSGGNEEDQLAQCQAYVQRHNIQQLVKEAIVVLCIHKPDNPVLFLKDHFEKLNEQRAQEGGNPDAADDDDIIVEPPKRSGGRRTGISAEPIKEDDTEYKKVVIPKDDATRRSLESAMRKNLLFAHLEEDEQKTMYDAMFPVEKSAGETIIEQGEEGDNFYVIDKGTVDVYVNHEYVLTINEGGSFGELALIYGTPRAATVIAKTDVKLWAIDRLTYRRILMGSVTKKRKMYDEFLSKVQILADLDQWERANVADALERCDFEPGTHVVEQGQPGDEFFIILEGEANVLQKRSDDAPFDVVGHLGMSDYFGEIALLLDRPRAATVVAKTHLKCIKLDRNRFERVMGPVREILKRDVSNYNSYVKLMT
Protein: Tumor necrosis factor alpha-induced protein 8-like protein 2 (TIPE2) (TNF alpha-induced protein 8-like protein 2) (TNFAIP8-like protein 2) (Q9D8Y7)
Organism: Mus musculus (Mouse)
Function: Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q6P589}. Nucleus {ECO:0000250|UniProtKB:Q6P589}. Lysosome {ECO:0000250|UniProtKB:Q6P589}.
Interaction partners:
- Caspase-8
Sequence:
MESFSSKSLALQAEKKLLSKMAGRSVAHLFIDETSSEVLDELYRVSKEYTHSRPKAQRVIKDLIKVAVKVAVLHRSGCFGPGELALATRFRQKLRQGAMTALSFGEVDFTFEAAVLAGLLVECRDILLELVEHHLTPKSHDRIRHVFDHYSDPDLLAALYGPDFTQHLGKICDGLRKLLDEGKL
Protein: DNA polymerase (EC 2.7.7.7) (Q585S7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU000442}.
Interaction partners:
- Proliferating cell nuclear antigen
- DNA polymerase delta subunit 2, putative
- Flap endonuclease 1
- DNA polymerase alpha subunit B
- DNA primase large subunit
- DNA polymerase epsilon catalytic subunit
- DNA primase
- DNA polymerase
- DNA polymerase II subunit 2
- DNA replication licensing factor MCM5
Sequence:
MTDSPDLSRPPVPPDYLQSDLLFQLLDCCQTQGSPHGIVSTVKHEDVPIVRIYGVTKEGHSVLVHCYNFEPHLWIRAPNRWLDVYSKTFVQELNASLDPLTHVSNTVVRIERHKRRSLMYYNPDGECDYLKVIVQLPQHIPRLRTLLSSGVMCVGAWEGLRAFPTFESNVIFPLRFMVDGNIGGCNWITVPAGQFHLFSPRTSTCQIEVCCSHEVLQSHEAVGDYLLIAPFRILSIDIECEGRKGLFPEAERDPVIQIANHCVNYGKEEDALTRTIFTLKSCGAIAGANVCSFETEEEMLVQWARFVKRIDPDFLTGYNICNFDFPYLLSRGITLKVNDSFFYWGRQLNERTVHREKKFLSRQLGNREYTELTMEGRVVMDVMAVIQRDYKLRAYSLNAVSQHFLGEQKEDVHHSIISDLQQGNDETRRRLAVYCLKDAYLPVKLLERLMVVVNNVEMARVTGVPIGWLLERGQQIKVFSMLLRKARARNFVVPTVETTGAEQRRYEGATVIEPKKGHYIEPIVTLDFASLYPSIIIAHNLCYSTLLPGHEVNNYESGMKEDTPTEHKFIRKEVFPGVLPEVLRDLLAARRQARALMKDVSQDSLEYKVLNGRQLALKVSANSVYGFTGAQVGRLPCLELSATVTSYGRRMIEETKQFVEKKYVGAEVIYGDTDSVMIRCVINADESDTNKLQQAMDFGKEAAEAVSSTFPDPIRLEFEKVYYPFLLMNKKRYAGLLWTNTVRYDKLDAKGIETVRRDSCPLVASVISGVLNRMLIQRSVESAVEFVKGTIRDLLHNRLDISQLVITKSFSKSESEYAGAQAHIALVERMRRRDPASAPNVGDRVAYVIVRAAKGAKAYERSEDPIYVLENNIPIDTQHYLEHQLGPPLLRVFEGVLQDPSVLTKGDHTRYVSVSAPNRNAGGLMKFVKFQLQCISCRSVIQEGALCDACSVMGPDIYGKIVAKRNHYEAVYSQVWTQCQQCQGSLNQEVICTSRDCPVFYLRKKVQKDVHEQQTLLDRFGVVDDW
Protein: Mitochondrial inner membrane protease ATP23 (EC 3.4.24.-) (Q9SRP6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:28936218}; Peripheral membrane protein {ECO:0000250|UniProtKB:P53722}; Intermembrane side {ECO:0000250|UniProtKB:P53722}. Note=Associates loosely with the inner membrane. {ECO:0000250|UniProtKB:P53722}.
Interaction partners:
- Mitochondrial metalloendopeptidase OMA1
- Mitochondrial ATP-independent inner membrane protease subunit 1a
- Mitochondrial inner membrane protease subunit 2
- Mitochondrial ATP-independent inner membrane protease subunit 2
- Peptidase S24/S26A/S26B/S26C family protein
- Mitochondrial ATP-independent inner membrane protease subunit 1b
- Mitochondrial intermediate peptidase, mitochondrial
- Probable thylakoidal processing peptidase 2, chloroplastic
- Intermediate cleaving peptidase 55, mitochondrial
- Organellar oligopeptidase A, chloroplastic/mitochondrial
Sequence:
MEDAAAPNSGSEFNPGARRGKSIDECQDMIRRSFRNPIVKFLMEQMEKSGCRVGDNFVKAVVCTGPVAGGYTKGRGITVCSNYLTIQDEVNQVVIHELIHAYDECRAKNLDWTNCAHHACSEIRAGHLSGDCHFKRELLRGFIKLRGHEQECIKRRVLKSLRGNPYCSEVAAKDAMEAVWDTCYNDTKPFDRAP
Protein: Speckle targeted PIP5K1A-regulated poly(A) polymerase (EC 2.7.7.19) (EC 2.7.7.52) (RNA-binding motif protein 21) (U6 snRNA-specific terminal uridylyltransferase 1) (F5H0R1)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus speckle {ECO:0000256|ARBA:ARBA00004324}. Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
Sequence:
MSLPIGSAEVASERVELWRSGFRWWQRCLCFCRYRRVAMAAVDSDVESLPRGGFRCCLCHVTTANRPSLDAHLGGRKHRHLVELRAARKAQGLRSVFVSGFPRDVDSAQLSEYFLAFGPVASVVMDKDKGVFAIVEMGDVGAREAVLSQSQHSLGGHRLRVRPREQKEFQSPASKSPKGAAPDSHQLAKALAEAADVGAQMIKLVGLRELSEAERQLRSLVVALMQEVFTEFFPGCVVHPFGSSINSFDVHGCDLDLFLDLGDLEEPQPVPKAPESPSLDSALASPLDPQALACTPASPPDSQPPASPQDSEALDFETPSSSLAPQTPDSALASETLASPQSLPPASPLLEDREEGDLGKASELAETPKEEKAEGAAMLELVGSILRGCVPGVYRVQTVPSARRPVVKFCHRPSGLHGDVSLSNRLALHNSRFLSLCSELDGRVRPLVYTLRCWAQGRGLSGSGPLLSNYALTLLVIYFLQTRDPPVLPTVSQLTQKAGEGEQVEVDGWDCSFPRDASRLEPSINVEPLSSLLAQFFSCVSCWDLRGSLLSLREGQALPVAGGLPSNLWEGLRLGPLNLQDPFDLSHNVAANVTSRVAGRLQNCCRAAANYCRSLQYQRRSSRGRDWGLLPLLQPSSPSSLLSATPIPLPLAPFTQLTAALVQVFREALGCHIEQATKRTRSEGGGTGESSQGGTSKRLKVDGQKNCCEEGKEEQQGCAGDGGEDRVEEMVIEVGEMVQDWAMQSPGQPGDLPLTTGKHGAPGEEGQPSHAALAERGPKGHEAAQEWSQGEAGKGASLPSSASWRCALWHRVWQGRRRARRRLQQQTKEGAGGGAGTRAGWLATEAQVTQELKGLSGGEERPETEPLLSFVASVSPADRMLTVTPLQDPQGLFPDLHHFLQVFLPQAIRHLK
Protein: Protein eiger [Cleaved into: Protein eiger, membrane form; Protein eiger, soluble form] (Q8MUJ1)
Organism: Drosophila melanogaster (Fruit fly)
Function: Cytokine which acts as a ligand for wgn. Also acts as a ligand for grnd. Induces apoptosis by triggering JNK signaling. Required for JNK-dependent non-autonomous apoptosis through release from apoptotic cells and activation of apoptosis in neighboring cells. Required for JNK-independent damage-induced apoptosis in the embryonic central nervous system through regulation of the pro-apoptotic gene hid. Involved in the innate immune response to extracellular pathogens. Plays a role in the melanization immune response through its involvement in the rupture of crystal cells and subsequent release of prophenoloxidase. Following UV-induced epidermal damage, released from apoptotic epidermal cells, binds to the wgn receptor on nociceptive sensory neurons and plays a role in development of thermal allodynia, a responsiveness to subthreshold thermal stimuli which are not normally perceived as noxious. Involved in glial cell division induced by neuronal programmed cell death and injury. Has tumor suppressor activity and eliminates oncogenic cells from epithelia, thereby maintaining epithelial integrity.
Subcellular location: [Protein eiger, membrane form]: Cell membrane {ECO:0000269|PubMed:12065414, ECO:0000269|PubMed:19289090, ECO:0000269|PubMed:25754009}; Single-pass type II membrane protein {ECO:0000255}.; SUBCELLULAR LOCATION: [Protein eiger, soluble form]: Secreted {ECO:0000269|PubMed:12894227}.
Interaction partners:
- Tumor necrosis factor receptor superfamily member wgn
- Tumor necrosis factor receptor superfamily member grnd
- Stress-activated protein kinase JNK
- Mitogen-activated protein kinase kinase kinase 7
- protein-tyrosine-phosphatase
- Caspase Dronc
- Death-associated inhibitor of apoptosis 1
- Protein lap4
- Cell death protein rpr
- GH01161p
Sequence:
MTAETLKPFITPTSANDDGFPAKATSTATAQRRTRQLIPLVLGFIGLGLVVAILALTIWQTTRVSHLDKELKSLKRVVDNLQQRLGINYLDEFDEFQKEYENALIDYPKKVDGLTDEEDDDDGDGLDSIADDEDDDVSYSSVDDVGADYEDYTDMLNKLNNAHTGTTPTSETTAEGEGETDSASSASNDDNVFDDFTSYNAHKKKQERKSRSIADVRNEEQNIQGNHTELQEKSSNEATSKESPAPLHHRRRMHSRHRHLLVRKGESLLSARSEDSRPAAHFHLSSRRRHQGSMGYHGDMYIGNDNERNSYQGHFQTRDGVLTVTNTGLYYVYAQICYNNSHDQNGFIVFQGDTPFLQCLNTVPTNMPHKVHTCHTSGLIHLERNERIHLKDIHNDRNAVLREGNNRSYFGIFKV
Protein: LIM domain only 1 (A9ED79)
Organism: Sus scrofa (Pig)
Interaction partners:
Sequence:
MMVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQLDYEEGQLTGAFEPQAQ
Protein: 20-hydroxyecdysone protein (20-HE) (P29681)
Organism: Drosophila melanogaster (Fruit fly)
Function: Probably has an essential role in embryogenesis, induces morphogenesis of imaginal disks, and may participate in multimolecular aggregates.
Subcellular location: Secreted. Note=Secreted from the apical cell surface.
Interaction partners:
- Serpin 100A
- Serpin 43Aa
- GH22837p
Sequence:
MKPVALILVFLAISQARVLNLPKEAIDIPVAIVEDKEPPVALSLVKEEVKAEEVKPEEVKPIAQEEKAKDLKEEVKPEIKPEIKEQPKPDIKDEIKEDLKADIKEELKEKIEEQINELPNAKPLELKEKSLEAEEKPQEIKEEVQQPEIKKEATEIKEEPAQNILKSLPAEETVVVPAEELSPNPVEQEQSENQDAAHPQVRQATQATPTQQSTTQGNFVQQLIQNSPIGQFLNQFQPQPAAAAAPAAAQVQADDAAAAAPATPAPTVPGFLNPQAAITSAQQAVQNAAQSAVNATTQAFQGIQQFASNLGNQFQNTLSSLTGQQQQAVSTTPRPPGPIQQFVNNVFGGNNNATAAAPPAQQSGNPLQGIINFLGGNRPQNAPAAAPATQATEKPAVDDKIDPANDEVGEFVPESDNELRASGENIDDSFEDAGVPSNEVIVVNDDAGEEGNAVQNHPVATDAVAL
Protein: Di-N-acetylchitobiase (EC 3.2.1.-) (Q01460)
Organism: Rattus norvegicus (Rat)
Function: Involved in the degradation of asparagine-linked glycoproteins. Hydrolyze of N-acetyl-beta-D-glucosamine (1-4)N-acetylglucosamine chitobiose core from the reducing end of the bond, it requires prior cleavage by glycosylasparaginase.
Subcellular location: Lysosome.
Interaction partners:
- Cytochrome c oxidase subunit 3
- Cytochrome c oxidase subunit 2
Sequence:
MALSDLLELTLLLLLPLLERLSAEDCPCSEASLCRPIRHHRDFEVFVFDVGQKTWKSYDWSQITTVAVFGKYDSELMCYAHSKGARVVLKGDVALKDIINPTFRASWIAQKVALAKAQHMDGINIDIEQEVDCSSPEYEALTALVRETTEGFHREIEGSQVTFDVAWSPKGIDKRCYNYTGIADACDFLFVMSYDEQSQIWSECIAAANAPYNQTLTGYGDYLRMGISPRKLVMGIPWYGYDYICLNLSKDDVCAIAKVPFRGAPCSDAAGHQVPYRVIMKQVNSSVSGSQWNQDQQAPYYNYKDPTGRLHQVWYDNPRSISLKAAFVKHYGLRGIGMWNANCLDYSDDALAREQTEEMWGALRPRL
Protein: Collagen alpha-1(XXII) chain precursor (Collagen type XXII alpha 1 chain) (M5BFV8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Interaction partners:
Sequence:
MEFRFGLRISLVLTVLALTLYGGGVEGQRAGCKNVHYDLVFILDTSSSVGKENFEKIRQWVANLVESFDVGVDKTRVAVVRYSDRPTVEFNLARYKTLEEVKRAAGNIRYLGGNTKTGDAISFTTTNIFTERAGARPAAKGIQKVAILLTDGQSQDFVLEPSVAAAAAGIRLFAVGIGEALKEELEEIAAEPKSAHVFHVTDFDAIDKIRGRLRRRLCENVLCPNMKVQAGRFRPNSTSAGLTEVPGFDLMEFFNVRDFLGEKFEPGQTPYVRLGALPIVQKTEDVLPQGLPDEYAFVTTFKFRKTSRKEDWYLWQVYDKYGIPQVSIRLDGENRAVEYNAVGLTKDAVRAVFRNPEVDNLFDRNWHKIGMRVDSKSVSLFLDCKHIETLPIEEREDIDIQGKTVIGKRLYDSVPIDFDLQRMVIYCDGKQSEQETCCDIPGGLCEQTLVTEAPPVPLPTPKPTSAEQKKPAAANCSCPAGERGDTGLPGAPGPKGEKGDPGLKGAEGPPGLKGLKGERGQAVSIKGDRGEKGDSGEFGEPGLTGDRGEKGSDGLPGLAGKKGDKGERGDQGVAGEAGLPGPLGPKGIQGNAGPPGAPGAQGLSGGAGNKGEKGSTGDRGERGADGFPGKPGLPGKEGVRGLIGAPGPNGVKGEKGAQGPAGIPGDAVQLAGLKGETGAQGEAGLPGVDGLPGPPGPPGPPGLPGETGDTGPRGKKGDAGLPGVDGLPGPPGPQGPPGVSGSPGQTGPPGLPGEIGFSGKPGESGKPGSPGKDGADGFPGNDGEKGQKGESGQDGFPGKPGPKGDEGPPGPRGPPGERGESGLTGQVGPMGPKGERGNHGERGREGPSGAKGEKGDKGEIGPRGPAGAPGNVANVIPEPGEPGKPGEKGEKGDQGKPGDMGQRGLPGEQGFRGQPGPVGPKGDAGDKGEPGRHGDPGPPGLMGPQGSRGLPGNVGIPGSIGPPGIAGQKGDKGDGGKDGPPGPPGPTGEPGLRGEIGLPGKGKEGEKGDAGPPGIAGPPGLRGLPGNQGMQGMPGNRGPPGEGSPGSQGPPGPAGPPGAAGLRGPPGVAGVQGPAGHNGIPGRPGEKGSPGEPGKAADLSDLNLKGVCSDCPAGPPGQPGIPGPPGDKGHSGPPGKNGQDGYAGAPGPTGPAGPPGSDGAKGVKGDRGPAGTPGDKGEKGAPGPPGYPGAAGAMGQPGNDGNPGPVGTPGPPGEKGKEGMTGIQGPPGLPGLMGMMGKPGKDGRPGESGEPGKQGEPGQPGRDGLRGMPGFKGHRGEPGPPGSKGEEGKQGVPGREGQPGKDGNSGPPGPEGMRGPRGESGQPGEQGPTGKPGSQGNPGQPGHKGEAGSPGLPGFPGPKGPSGPPGPIGPEGKQGMLGKAGDRGQKGEKGDNGIKGDKGPVGDPGIPGNPGSPGRKGHTGMMGMSGPPGEVGPAGPPGTPGIPGLPGLRGETPSLEQMRRLIQDELSKQLDAKLAYLMAQMQPAHIKSTAGRPGPPGPPGKDGSPGRQGPTGEPGMPGQNGVEGLRGPAGPKGERGSKGEKGEDGVGQRGEPGPIGPMGPAGMPGDGKDGLPGAAGAQGEPGNPGPHGQPGPPGPTGQCDPSQCAYYASLASRPHTKNVKGT
Protein: Claudin-3 (Clostridium perfringens enterotoxin receptor 2) (CPE-R 2) (CPE-receptor 2) (Q9Z0G9)
Organism: Mus musculus (Mouse)
Function: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Subcellular location: Cell junction, tight junction {ECO:0000269|PubMed:24588076, ECO:0000269|PubMed:9892664}. Cell membrane {ECO:0000269|PubMed:24588076, ECO:0000269|PubMed:9892664}; Multi-pass membrane protein {ECO:0000269|PubMed:9892664}.
Interaction partners:
- Occludin
- Tight junction protein ZO-3
- Tight junction protein 1
- Claudin-5
- Claudin-12
- Claudin-7
- MARVEL domain-containing protein 2
- Claudin-16
- Tight junction protein 2
- MARVEL
Sequence:
MSMGLEITGTSLAVLGWLCTIVCCALPMWRVSAFIGSSIITAQITWEGLWMNCVVQSTGQMQCKMYDSLLALPQDLQAARALIVVSILLAAFGLLVALVGAQCTNCVQDETAKAKITIVAGVLFLLAALLTLVPVSWSANTIIRDFYNPLVPEAQKREMGAGLYVGWAAAALQLLGGALLCCSCPPRDKYAPTKILYSAPRSTGPGTGTGTAYDRKDYV
Protein: Uncharacterized protein (Q38DZ6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLIFLSCFTSVPIPNICRALCVRRATIMASIGPKLSRRQKLHVHLKAVLQALPISILIVAEGRDMYYRATWEVTELPPGAFRTGDVIAICNRWYTLPTWGHKLYSVLSKVLLKSSWDDVGVIWVKEGVPHVFFSDFTGAHVLSLEKFIKDRMPRGIALRRLVVADADAGRKPNAAVASVFAEEVQKLEPHPWYLFSASMRYNREHKHYECVVDMCRQRCKIYQMIKSGASNSAINGQKEKLKEMEVMKQHLATFVEPDKTFRLFNGSLVASFLATFDLLDRSMPPPSRYVPQDFAHDLPFKCVAALEEPVVFFKN
Protein: Protein slender lobes (Q8INM3)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required for the correct organization of the nucleolus during development.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:15848394}.
Interaction partners:
Sequence:
MVVTRARTRRLSLLETDSRPSTPQLDTVAELGTASPRATRRTRLNSSTLDVRTPTRTRRASLARGETPEPTTPSSVKRTARTPAKNTRSVRQQLTLTEEPEENEVKQEKPSPSPSPVPKEGKGKAQRKPSVSPSPGRTLTPNQQSDEKRVTRSMSQTPPMPTRSSSNTPRDLNDSPKVEQKAKPNIKTTPKVAVRLEKLSMDKFSGKKMEKAKPLIVPDELKDNGVVEEQNKSITEAHSQAPETHESAQPDKDAGKQSFLKSFTTLSKIQGSSKALHPDESADTITKITPTSTSKKIEENMDDVFETLRVESPKVERKIETLQKVHTVGTPEIKEKDEPVGVDNEIKTKTETPQKIEPPIIESKVETQQLIDHPQIEKKRDTPQNVSTVDLMDTSPEKDESMEDQEFLDAEDSIVQLEPQTDEPVEKPKELEFVDLDDDEPVFPSEAPKYVEDSKEVHPDDSMDDDKQNKIDVTEVIHLPSIRARAVRSPAVEQKKSVDFNNDTDDLEVEKKRFPKTPGREKVPVCRILTPKPETPLKLALQKGRNSSTPILKDQERGLSNSTEELHPAPPQIDAIKPFDELESKNAKDEMVEQSPMSKQKAENKILARLESFEEDVEDHGNEEENEEEHEEDKSISEFVDLEAEDAGKDYMSGDSMDSSLRREMEENEIPIDGESVGSKDTEESTPEESDGDDSFIVSDNEDEEDLGQLCYSSGEDEIEDAEESEQAERSSVKRRRIIIASPSDEEHDGKVQSNDDSSENKTEKPKNQSNCSSNASKLSEAAQLLNVSEEKSSISETELERSRQVALNELNKSERFNKTETQLDISVMEVDSSDHDEEEKTEKVGAKNNRSLYEIVDSDDGEEQDQDQSDADKPAESENHSEIKKSTSFMDQMSGAKGNKSVYEIMDSYETEDPKEAGKNEESDKDKPAENGKSDKDKQAETEMSDEDKPSEIKSPSTIKKSIISTADEEALLAELASSDLSHLEKMFNPLQKSRRQSLHVPSPELAAKNPKLRRRSERVEVGNDFCPSQSFVDMVAEKKRQKNKRKRLSKSLSGAPEDLEEMEIKHERKRLKSSHGASTDSMEEDNENETMTVAEEHHSDGEVSNGEVPIEEKPTTSSEKPSASELPEEEETVAVEELLMEKPKTCDSPRSEERPTEIVTSKPKGMAPVKVEKTAEYYLAYCHNLLEAANEAKLKEKKEHLASGAKQKKPKRIAAQAPSKLLGTIGSESETNTAKSSKQPPALKKDVKRLQAARQAVSHAVNLLAPPKATEAEPRTLSRKLSPQPPVVDKKSAKQKKGKKKQKPQEASPLKSSDEENHGHRIRTNAGYVTVVDEPPTKVPKIELIKTSSGMVRVEPCTPKQKYFRELPPTPKMHGFREEPGPSGMSRKRAKHAAPKVEHNSAKQAALRFKEQIFARRS
Protein: Tubulin alpha 4a (C9JDS9)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
Sequence:
MERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRH