wanglab/gogpt-training-data huggingface dataset:
Protein: Peroxisomal ATPase pex6 (EC 3.6.4.-) (Peroxin-6) (Peroxisome biosynthesis protein pex6) (O13764)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling. Specifically recognizes PEX5 monoubiquitinated at 'Cys-6', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel. Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:16823372}. Peroxisome membrane {ECO:0000250|UniProtKB:P33760}; Peripheral membrane protein {ECO:0000250|UniProtKB:P33760}; Cytoplasmic side {ECO:0000250|UniProtKB:P33760}.
Interaction partners:
- Peroxisomal ATPase pex1
- Peroxisomal targeting signal receptor
- Peroxisomal membrane protein pex13
- Peroxisomal membrane protein pex14
- Peroxisomal biogenesis factor 11
- Mitochondrial 2-methylisocitrate lyase
- Uncharacterized protein C17C9.14
- Peroxisomal targeting signal 2 receptor
- Probable proteasome subunit beta type-5
Sequence:
MENRICTLAKPLPKLDESKQAWVSYLWLKKALPGFEEHSAYVYMTTNPTIAGRIFLPINNEDLEDGTVEISGYDNLLADALYISTIAPVKLDFVQLIVIDDNSQDQDAIIERIKGRNAILMESDFINQNILVQVCQPVRHGVVDSETKFVIERKDSFTFLASNEKNISSFKRGKTETDAELVIRPSKVHTEIQWCLQNCSLIHVPFELLFNVGKKNGCPISLRLSDGKNVYGIASIKSDTEHDSVQLSPSLHYFDEFNESVISEEGTEAFLVARGPSVGIASRISLRTIPTQSCFSEKLLKAANLCVVQQVKQKVFLQSKQIFCVPINSLMANSDSVDILELTRNTDAYIWYSVEEIDPLNTYNIYYTNEDTSIVLDTQLSHRLLPSLRKPLLNFVKVHPPSQKLLRFCRAFFDPQQVPGFNPFFLLHGNPFTGKTKAVEEVASLFSAPVFTISSYEFADATADHLEAKLDMFVQNVVKSPCAIIFVKDLDVLSISSDEGNIVPGSKSIQILLSKIDLVKSPQGRYIVIGTCHSIEKIPYEILSESFFELKFSELEMDERLELLKIYANNVIIDKRISLKDVALKTNSMSFGELECLPDHMTKAAVDRIKRTGYDNDSIILSGPIITEQDVDVSINRIRKEKSNTIFTVPKVNWDDIGGLEEAKTVLRDTLQLPLQFPELFSQGLKPRSGVLLYGPPGTGKTLLAKAVATELSLEFVSIKGPELLNMYVGESEANVRNVFEKARNSSPCVIFFDELDSIAPHRGNSSDSGNVMDRVVSQLLAELDSISKDNNKYVFVIGATNRPDLLDPSLLRPGRFDKLVYLGINKSEESKASMLRALTKTFKLDETIDLNEIAKNCHPNFTGADMYALCSDAVLSAIKRKTNEIDLLIQASGTDLSTEEFFKRNENQDSLELRITKEDFLTSLKKLRPSISEQELHRYEMVRHQFS
Protein: TBC1 domain family member 21 (Male germ cell Rab GTPase-activating protein) (Q9D9D3)
Organism: Mus musculus (Mouse)
Function: Acts as a GTPase-activating protein for Rab family protein (s). Essential for the establishment of male fertility, and is required for both the production of normal sperm number and sperm function. Plays an important role in the formation of intact mitochondria, outer dense fibers and axoneme within the sperm tail. Essential for sperm mitochondrial sheath formation and for the interactions of ARMC12 with VDAC2 and VDAC3. May be involved in acrosome formation and cytoskeletal reorganization during spermiogenesis, possibly by regulating RAB3A activity.
Subcellular location: Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:21128978}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:21128978}. Note=Located at the edge of the acrosomal region, neck and annulus during spermiogenesis. Colocalizes with RAB3A at the acrosome-acroplaxome and neck regions of spermatids. Colocalizes with ACTB at the neck region in elongated spermatids. {ECO:0000269|PubMed:21128978}.
Interaction partners:
- Armadillo repeat-containing protein 12
- Carabin
- TBC1 domain family, member 19
- TBC1 domain family member 13
Sequence:
MTTLSPENSLSARRSATFILEKRNPPIDKAEWDSFFDENGHLAKSRDFICINILERGLHPFVRTEAWKFLTGYYSWQSSRDERLMVDSNRRRNYNSLCQMYEKIQPLLENLHGNFTETRNNIAYDIQRLYDKDPLGNVLIDKKKLEKTLLLSYVCNTKAEYQRGFHEMVMLFQLMVEHDHETFWLFQFFLQKTEHSCVINIGVGKNLDMLNSLITLLDPEFAEHLKGKGSGAVQSLFPWFCLCFQRAFKTFDDVWRLWEVLLTGKPCRNFQVLVAYSMLQMVREQALLECMSGDAILMACNNLIDLDADELISAACVVYSELMQKEVPQPLKEFLL
Protein: Rho guanine nucleotide exchange factor 17 (164 kDa Rho-specific guanine-nucleotide exchange factor) (p164-RhoGEF) (p164RhoGEF) (Tumor endothelial marker 4) (Q96PE2)
Organism: Homo sapiens (Human)
Function: Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases.
Interaction partners:
- Transforming protein RhoA
Sequence:
MADGAPRPQLYRSVSFKLLERWSGGPGLREEDTDTPGLRRRASCRPTTAARGQPSRRVSKLASGPLAAPAQPRPLRSLSPSVRQLSRRFDAPRLDDGSAGTRDGGVLPAAAEEAAEGPARGAWPSVTEMRKLFGGPGSRRPSADSESPGTPSPDGAAWEPPARESRQPPTPPPRTCFPLAGLRSARPLTGPETEGRLRRPQQQQERAQRPADGLHSWHIFSQPQAGARASCSSSSIAASYPVSRSRAASSSEEEEEGPPQLPGAQSPAYHGGHSSGSDDDRDGEGGHRWGGRPGLRPGSSLLDQDCRPDSDGLNLSSMNSAGVSGSPEPPTSPRAPREEGLREWGSGSPPCVPGPQEGLRPMSDSVGGAFRVAKVSFPSYLASPAGSRGSSRYSSTETLKDDDLWSSRGSGGWGVYRSPSFGAGEGLLRSQARTRAKGPGGTSRALRDGGFEPEKSRQRKSLSNPDIASETLTLLSFLRSDLSELRVRKPGGSSGDRGSNPLDGRDSPSAGGPVGQLEPIPIPAPASPGTRPTLKDLTATLRRAKSFTCSEKPMARRLPRTSALKSSSSELLLTGPGAEEDPLPLIVQDQYVQEARQVFEKIQRMGAQQDDGSDAPPGSPDWAGDVTRGQRSQEELSGPESSLTDEGIGADPEPPVAAFCGLGTTGMWRPLSSSSAQTNHHGPGTEDSLGGWALVSPETPPTPGALRRRRKVPPSGSGGSELSNGEAGEAYRSLSDPIPQRHRAATSEEPTGFSVDSNLLGSLSPKTGLPATSAMDEGLTSGHSDWSVGSEESKGYQEVIQSIVQGPGTLGRVVDDRIAGKAPKKKSLSDPSRRGELAGPGFEGPGGEPIREVEPMLPPSSSEPILVEQRAEPEEPGATRSRAQSERALPEALPPPATAHRNFHLDPKLADILSPRLIRRGSKKRPARSSHQELRRDEGSQDQTGSLSRARPSSRHVRHASVPATFMPIVVPEPPTSVGPPVAVPEPIGFPTRAHPTLQAPSLEDVTKQYMLNLHSGEVPAPVPVDMPCLPLAAPPSAEAKPPEAARPADEPTPASKCCSKPQVDMRKHVAMTLLDTEQSYVESLRTLMQGYMQPLKQPENSVLCDPSLVDEIFDQIPELLEHHEQFLEQVRHCMQTWHAQQKVGALLVQSFSKDVLVNIYSAYIDNFLNAKDAVRVAKEARPAFLKFLEQSMRENKEKQALSDLMIKPVQRIPRYELLVKDLLKHTPEDHPDHPLLLEAQRNIKQVAERINKGVRSAEEAERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLGQMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDSYIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTLNSCPEPSPEVWVCNSDGYVGQVCLLSLRAEPDVEACIAVCSARILCIGAVPGLQPRCHREPPPSLRSPPETAPEPAGPELDVEAAADEEAATLAEPGPQPCLHISIAGSGLEMTPGLGEGDPRPELVPFDSDSDDESSPSPSGTLQSQASRSTISSSFGNEETPSSKEATAETTSSEEEQEPGFLPLSGSFGPGGPCGTSPMDGRALRRSSHGSFTRGSLEDLLSVDPEAYQSSVWLGTEDGCVHVYQSSDSIRDRRNSMKLQHAASVTCILYLNNQVFVSLANGELVVYQREAGHFWDPQNFKSVTLGTQGSPITKMVSVGGRLWCGCQNRVLVLSPDTLQLEHMFYVGQDSSRCVACMVDSSLGVWVTLKGSAHVCLYHPDTFEQLAEVDVTPPVHRMLAGSDAIIRQHKAACLRITALLVCEELLWVGTSAGVVLTMPTSPGTVSCPRAPLSPTGLGQGHTGHVRFLAAVQLPDGFNLLCPTPPPPPDTGPEKLPSLEHRDSPWHRGPAPARPKMLVISGGDGYEDFRLSSGGGSSSETVGRDDSTNHLLLWRV
Protein: Cation uptake regulator (Q5F961)
Organism: Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
Interaction partners:
- Cobalamin biosynthesis protein CobW
Sequence:
MKTNFKQKIIEQARREDLQVTALREQVLDIVLQQSGVIKAYNVLSQMQQQSEGVLAPPTAYRALDFWADQGVLHKVAAVNGYILCSHAQHECNDHCHDHEEAEAHHSAFILVCTECGAADEQTLSHEWAALRAGVAESGFALKEEHVVLTGICKKCQK
Protein: Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) (Monocyte/macrophage protein 19) (Q9WVQ5)
Organism: Mus musculus (Mouse)
Function: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03116}.
Interaction partners:
- Enolase-phosphatase E1
- Methylthioribose-1-phosphate isomerase
- Acireductone dioxygenase-requiring))
- Apoptotic protease-activating factor 1
Sequence:
MSGCQAQGDCCSRPCGAQDKEHPRFLIPELCKQFYHLGWVTGTGGGISLKHGNEIYIAPSGVQKERIQPEDMFVCDINEQDISGPPASKKLKKSQCTPLFMNAYTMRGAGAVIHTHSKAAVMATLLFPGQEFKITHQEMIKGIRKCTSGGYYRYDDMLVVPIIENTPEEKDLKERMAHAMNEYPDSCAVLVRRHGVYVWGETWEKAKTMCECYDYLFDIAVSMKKMGLDPTQLPVGENGIV
Protein: Altered inheritance rate of mitochondria protein 29 (P36154)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May be involved in mitochondrial organization and biogenesis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11914276}.
Interaction partners:
- Protein PBDC1 homolog
- Protein HGH1
- Pyridoxal phosphate homeostasis protein
Sequence:
MNSTKRLKMSTTFHDYDLEEPLTSNARPLKNSVITIRVIKSFPYRNVKNIVLHDYDLADKTAKDLFNDVLNKIQNEGSFRPFRNVKFDTLKIYTHAHGSKTVNLVINFDHDDDWTLDIENDKKKLFEYGIENETEISLFNKEDYLRFKENPEEKW
Protein: Epididymis luminal protein 104 (Zinc finger protein 354A) (V9HWI2)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAAGQREARPQVSLTFEDVAVLFTRDEWRKLAPSQRNLYRDVMLENYRNLVSLGLPFTKPKVISLLQQGEDPWEVEKDGSGVSSLGSKSSHKTTKSTQTQDSSFQGLILKRSNRNVPWDLKLEKPYIYEGRLEKKQDKKGSFQIVSATHKKIPTIERSHKNTELSQNFSPKSVLIRQQILPREKTPPKCEIQGNSLKQNSQLLNQPKITADKRYKCSLCEKTFINTSSLRKHEKNHSGEKLFKCKECSKAFSQSSALIQHQITHTGEKPYICKECGKAFTLSTSLYKHLRTHTVEKSYRCKECGKSFSRRSGLFIHQKIHAEENPCKYNPGRKASSCSTSLSGCQRIHSRKKSYLCNECGNTFKSSSSLRYHQRIHTGEKPFKCSECGRAFSQSASLIQHERIHTGEKPYRCNECGKGFTSISRLNRHRIIHTGEKFYNCNECGKALSSHSTLIIHERIHTGEKPCKCKVCGKAFRQSSALIQHQRMHTGERPYKCNECGKTFRCNSSLSNHQRIHTGEKPYRCEECGISFGQSSALIQHRRIHTGEKPFKCNTCGKTFRQSSSRIAHQRIHTGEKPYECNTCGKLFNHRSSLTNHYKIHIEEDP
Protein: Plastin-2 (L-plastin) (LC64P) (Lymphocyte cytosolic protein 1) (LCP-1) (P13796)
Organism: Homo sapiens (Human)
Function: Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:16636079}. Cell junction {ECO:0000269|PubMed:17294403}. Cell projection {ECO:0000269|PubMed:16636079}. Cell projection, ruffle membrane {ECO:0000250|UniProtKB:Q61233, ECO:0000269|PubMed:16636079}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q61233}; Cytoplasmic side {ECO:0000250|UniProtKB:Q61233}. Note=Relocalizes to the immunological synapse between peripheral blood T-lymphocytes and antibody-presenting cells in response to costimulation through TCR/CD3 and CD2 or CD28 (PubMed:17294403). Associated with the actin cytoskeleton at membrane ruffles. Relocalizes to actin-rich cell projections upon serine phosphorylation (PubMed:16636079). {ECO:0000250|UniProtKB:Q61233, ECO:0000269|PubMed:16636079, ECO:0000269|PubMed:17294403}.
Interaction partners:
- Actin, alpha skeletal muscle
- Hematopoietic lineage cell-specific protein
- Grancalcin
- Plastin-3
- Fascin
- Lysosomal-associated transmembrane protein 5
- Actin, cytoplasmic 1
- Signal transducer and activator of transcription 4
- Actin, cytoplasmic 2
- Integrin beta-2
Sequence:
MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFDEFIKIFHGLKSTDVAKTFRKAINKKEGICAIGGTSEQSSVGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTINKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYHLLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNPKLNLAFIANLFNRYPALHKPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYPKLGGNMKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNILEEIGGGQKVNDDIIVNWVNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVFACLMGKGMKRV
Protein: FI03681p (KAL-1) (Kallmann syndrome 1) (RH39295p) (Q9VCC7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Fibroblast growth factor receptor homolog 2
- Fibroblast growth factor
Sequence:
MGSMQVALLALLVLGQLFPSAVANGSSSYSSTSTSASNQLQRQKLAHWFRDSNDVKDKILELQCLAKCGSNPTTKAGREQCLNKCIQELLLGPRAGSCPKIGRQSRARLSCLDNCQYDHECPEVQKCCPSSCGPMCVEPLGVRNNTQLPPIPKILYFRRSRGHAVDLKIESSLLVYYFHVEVRSHIGRHFAARKLGPWQWQKVEKTMEENIGHSKHTYIFFHMRPGRWYEVRVAAVNAYGFRGYSEPSDPFPSTGNPKPPKSPNDSKIIGKQFDGRYMTLKLVWCPSKSNLPVEKYKITWSLYVNSAKASMITNSSYVKDTHQFEIKELLPNSSYYIQVQAISYLGSRRLKSEQWSMLFNTTLQPLEPITPLQCSGNGNRRRHHHTSSSMSSERATTSEPVALNEVSPTITNRTSAAATYEVGFRLNRKFGMIVQILGFQPHKEKVYELCPQETNCEQREFRAIRAKKDPLEFSKLKYNTTYVLRIPRSSPNSVLDDSRNVFTFTTPKCENFRKRFPKLQIKCSD
Protein: Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase I (EC 2.4.1.135) (Beta-1,3-glucuronyltransferase I) (Glucuronosyltransferase I) (DmGlcAT-I) (UDP-GlcUA:Gal beta-1,3-Gal-R glucuronyltransferase) (GlcUAT-I) (O97422)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on both glycolipids and glycoproteins. Shows strict specificity for Gal-beta-1,3-Gal-beta-1,4-Xyl, exhibiting negligible incorporation into other galactoside substrates.
Subcellular location: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Hexosyltransferase
- 2-phosphoxylose phosphatase 1
- Beta-1,4-galactosyltransferase 7
- Hexosyltransferase
- Coiled-coil domain-containing protein 130 homolog
- Hexosyltransferase
- Exostosin-2
- UDP-glucuronic acid decarboxylase 1
Sequence:
MSEVRIRPRQVLILIIVFLVVLMMVHRNGKRTCQGPEYLQAMFVQGDTLPTIYAVTPTYPRPAQKAELTRLSHLFMLLPHLHWIIVEDTNATTPLVRNLLDRAGLEKRSTLLNIKTPSEFKLKGKDPNWIKPRGVEQRNLALAWLRNHVDVDRHSIVFFMDDDNSYSTELFAEMSKIERGRVGVWPVGLVGGLMVERPLLTEDGTKVTGFNAAWRPERPFPIDMAAFAISMDLFIRNPQATFSYEVQRGYQESEILRHLTTRDQLQPLANRCTDVLVWHTRTEKTKLAAEEALLKKGQRSDGGMEV
Protein: Probable methyltransferase PMT1 (EC 2.1.1.-) (Q8H118)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MRGRSEGGKKKPVIVLLCVASVVLVFVYLFFGSSNHKAIEYGRKLGLGGDDDDSTKKDDTSSSFYVEDVVGNGFTPRSFPVCDDRHSELIPCLDRNLIYQMRLKLDLSLMEHYERHCPPPERRFNCLIPPPPGYKIPIKWPKSRDEVWKVNIPHTHLAHEKSDQNWMVVKGEKINFPGGGTHFHYGADKYIASMANMLNFPNNVLNNGGRLRTFLDVGCGVASFGGYLLASEIMTMSLAPNDVHQNQIQFALERGIPAYLGVLGTKRLPYPSRSFELAHCSRCRIDWLQRDGILLLELDRVLRPGGYFAYSSPEAYAQDEEDLRIWREMSALVGRMCWTIAAKRNQTVIWQKPLTNDCYLGREPGTQPPLCNSDSDPDAVYGVNMEACITQYSDHDHKTKGSGLAPWPARLTSPPPRLADFGYSTDIFEKDTETWRQRVDTYWDLLSPKIQSDTVRNIMDMKASMGSFAAALKEKDVWVMNVVPEDGPNTLKLIYDRGLMGAVHSWCEAFSTYPRTYDLLHAWDIISDIKKRGCSAEDLLLEMDRILRPSGFILIRDKQSVVDLVKKYLKALHWEAVETKTASESDQDSDNVILIVQKKLWLTSESLRDLE
Protein: Stanniocalcin (STC) (Corpuscles of Stannius protein) (CS) (Hypocalcin) (Teleocalcin) (P43648)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Function: Its primary function is the prevention of hypercalcemia. Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment. STC also stimulates phosphate reabsorption by renal proximal tubules. The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.
Subcellular location: Secreted.
Interaction partners:
Sequence:
MLAKFGLCAVFLVLGTAATFDTDPEEASPRRARFSSNSPSDVARCLNGALAVGCGTFACLENSTCDTDGMHDICQLFFHTAATFNTQGKTFVKESLRCIANGVTSKVFQTIRRCGVFQRMISEVQEECYSRLDICGVARSNPEAIGEVVQVPAHFPNRYYSTLLQSLLACDEETVAVVRAGLVARLGPDMETLFQLLQNKHCPQGSNQGPNSAPAGWRWPMGSPPSFKIQPSMRGRDPTHLFARKRSVEALEREME
Protein: AT19426p (Radial spoke head protein 1) (Q9VK29)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- GH13165p
- Radial spoke head protein 9 homolog
- GH13213p
- Zinc finger MYND domain-containing protein 10 homolog
- Putative inner dynein arm light chain, axonemal
- Spag1 axonemal dynein assembly factor
- Dynein, axonemal, intermediate chain 2, isoform C
- Dynein regulatory complex subunit 4
- AT09290p
- FI20425p1
Sequence:
MAMTEMSEEDLSAPEEEEDLGPNIGLYIGGRNAAGQRQGRGWAILPNGDQYDGNYRKGRRHGIGVYVFKDGSRYYGQYRCGKRCGRGIFIYPDGSVYEGNWRKNLKHGKGRYKYVNGDNYSGDWFKGQRHGVGIYHFNSGKDGCCLSVRMKATWNSNMRTGPFELYIGNEDKCTILHGIWDNLYPSGPAVFSFNNRYLLLGYFLPASYNMKAISNEDEMEDAEERLEDEMGEAEPMEPTLWFAQEMAVYDFSLLPQEPVPLAISDSELSVCSLSTEPSMRSEEKISWYGEGEEAEGEEGGEMECFPCECDLTDVSEVETESEVCKIDANPCCIEILKQPECPDP
Protein: Calcium-transporting ATPase 1 (EC 7.2.2.10) (Ca(2+)-ATPase isoform 1) (Plastid envelope ATPase 1) (Q37145)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol out of the cell or into organelles.
Subcellular location: Plastid, chloroplast inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Extensin-like protein
- Putative disease resistance protein At3g15700
- Alpha carbonic anhydrase 5
- Chloroplastic calcium uniporter protein
- GroES-like zinc-binding alcohol dehydrogenase family protein
Sequence:
MESYLNENFGDVKPKNSSDEALQRWRKLCWIVKNPKRRFRFTANLSKRSEAEAIRRSNQEKFRVAVLVSQAALQFINSLKLSSEYTLPEEVRKAGFEICPDELGSIVEGHDLKKLKIHGGTEGLTEKLSTSIASGISTSEDLLSVRKEIYGINQFTESPSRGFWLFVWEALQDTTLMILAACAFVSLIVGILMEGWPIGAHDGLGIVASILLVVFVTATSDYRQSLQFKDLDAEKKKIVVQVTRDKLRQKISIYDLLPGDVVHLGIGDQIPADGLFISGFSVLINESSLTGESEPVSVSVEHPFLLSGTKVQDGSCKMLVTTVGMRTQWGKLMATLSEGGDDETPLQVKLNGVATIIGKIGLFFAVITFAVLVQGLANQKRLDNSHWIWTADELMAMLEYFAVAVTIVVVAVPEGLPLAVTLSLAFAMKKMMNDKALVRNLAACETMGSATTICSDKTGTLTTNHMTVVKACICEQAKEVNGPDAAMKFASGIPESAVKLLLQSIFTNTGGEIVVGKGNKTEILGTPTETALLEFGLSLGGDFQEVRQASNVVKVEPFNSTKKRMGVVIELPERHFRAHCKGASEIVLDSCDKYINKDGEVVPLDEKSTSHLKNIIEEFASEALRTLCLAYFEIGDEFSLEAPIPSGGYTCIGIVGIKDPVRPGVKESVAICKSAGITVRMVTGDNLTTAKAIARECGILTDDGIAIEGPEFREKSDEELLKLIPKLQVMARSSPMDKHTLVRLLRTMFQEVVAVTGDGTNDAPALHEADIGLAMGISGTEVAKESADVIILDDNFSTIVTVAKWGRSVYINIQKFVQFQLTVNVVALIVNFLSACLTGNAPLTAVQLLWVNMIMDTLGALALATEPPQDDLMKRSPVGRKGNFISNVMWRNILGQSLYQLVIIWCLQTKGKTMFGLDGPDSDLTLNTLIFNIFVFCQVFNEISSREMEKIDVFKGILKNYVFVAVLTCTVVFQVIIIELLGTFADTTPLNLGQWLVSIILGFLGMPVAAALKMIPVGSH
Protein: IQ motif containing GTPase activating protein 3 (B9EKT6)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MEPCAAGRARTAYERLTAEEMDEQRRQNVAYQYLCRLEEAKRWMEVCLKEELPSPVELEESLRNGVLLAKLGHCFAPSVVPLKKIYDVEQLRYQATGLHFRHTDNINFWLSAVAHIGLPSIFLPETTDIYDKKNMPRVIYCIHALSLFLFRLGLAPQIHDLYGKVKFTAEELGNIASELAKYGLQLPAFSKIGGILANEFSADEAAVHAAILAINDAVERGVVEDTLVTLQNPNALLGNLREPLAAVYQELLALAKMEKAANARNHDDGQEQDIYESCLTQAEIQGHINLANVQGALEVVDDALERQNPGALLEALHDPVLALQGVRGTFADWYLEQLTSDREQKSQELGLVRLLEKEEIQAGVAVANEKGNEEQTMLQAVWRINKAIRRGVAADTVKELMCPEAQLPRVYPFASAFYQQELALLQKQQQGELGQEELFVAVEMLSAVVLINRALEAGDVCAFWDNLVNPATGLAQVEEENAQRYFDALVKVQQFQGTHRGILSWNDLQAAVSQVNEQVQEETDQVLAISLINEALDQGCPEKTLSALLLPAAGLEDVSLHVAPRYHLLLVAAKRQKARVTGDPGAVLWLEEIRQGVARANEDTSTAQRIALGVAAINQAIKEGKAAQTERVLRNPNVALRGIVPDCAKSYQQALEGAAAKKQCPGDTAFWVQHDMKDGTAYYLHLQTFQGTWEHPSGCHLNTSHLTWEEIQSVITKVTAAHDRQLLWKANVGFVIKLQARLRGFLVRQKFAESSHVFRTLLPAVIKIQAHWRGYRQRKAYQERLQHFKANLDAIIKIQAWARMWAARRRYLRRLRYFQKNVDSVVKIQAFFRARKARDDYRMLVHARHPPLCVVRKFAHLLNQSQEDFSAEAELLKLQEEVVRKIRSNQQLEQDLNLMDIKIGLLVKNRITLQEVVSHCKKLTKKNKEQLSDMMILDKQKGLKSLSREKRQKLEAYQHLFYLLQTQPIYLAKLIFQMPQNKTTKFMEGVIFSLYNYASNRREAYLLLQLFRTALQEEIKSKVEQPQDVVTGNPTVVRLVVRFYRNGRGQSALQEILGKVIQDVLEDRSVSIHTDPVHIYKSWINQEEAQTGQRSHLPYDVTPEQALSHSEVQRRLDISLRSLLTLTEKFFVAISSSVDHIPYGMRYMAKVLKTTLEKKFPNATERDIYKVVGNLLYYRFLNPAVVAPDAFDIVAMVAGSTLAAPQRHALGAVAQLLQHAAAGQIFSGESRHLRVLNDYLEDLHLKFRKFICRACRVPEPEERFAIDEYSDMVAVAKPMVYITVGELIGTHRLLLEHQDQLAPGHQDPLHQLLEDLGEPPTISDLIGDNIATDGHVDLSRLEVSLTLTNKFEGLETDADHNSNQSLLLSTKQMLADLIQFHPGESLEEILTSSAPREHEEAHRRLMCWRQACDTQKPEPLRRHHSLMAHSLLSLSEKQQRVLRNLRRLQGLGLVRASDCYQGLVDELAKDICNQRRHRQRRKAEMLRLRTTLQGLDAKTIFYEEQGDYYNQYIQACLDHLAPKPKSSGKGKKQPSLHYTAAQLLEKGVLVEIEDLPVSHFRNVIFDITPGDEAGRFFVNAKFLGVDMEKFQLHYQDLLQLQYEGVAVMKLFNKAKVNVNLLIFLLNKKFLRK
Protein: LysM and putative peptidoglycan-binding domain-containing protein 2 (Q8IV50)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MADSSPALSLREGGPRAPRPSAPSPPPRSRSGSESEEAELSLSLARTKTRSYGSTASVRAPLGAGVIERHVEHRVRAGDTLQGIALKYGVTMEQIKRANKLFTNDCIFLKKTLNIPVISEKPLLFNGLNSIDSPENETADNSFSQEEEPVVAGEDLPPPSPQESDVQPVQPEEVSARDFLQRLDLQIKLSTQAAKKLKEESRDEESPYATSLYHS
Protein: Inhibitor of apoptosis protein (IAP) (Inhibitor of T-cell apoptosis protein) (Q90660)
Organism: Gallus gallus (Chicken)
Function: Apoptotic suppressor.
Subcellular location: Nucleus. Cytoplasm. Note=Predominantly nuclear. According to PubMed:9372964 it is cytoplasmic.
Interaction partners:
- TNF receptor superfamily member 1A
- TNFRSF1A associated via death domain.
- Uncharacterized protein.
- Mitogen-activated protein kinase kinase kinase 7.
- Caspase 9
- Uncharacterized protein.
- Caspase-3
- TNF receptor-associated factor
- Caspase-7
- E3 ubiquitin-protein ligase XIAP
Sequence:
MNIMDSSPLLASVMKQNAHCGELKYDFSCELYRMSTFSTFPVNVPVSERRLARAGFYYTGVQDKVKCFSCGLVLDNWQPGDNAMEKHKQVYPSCSFVQNMLSLNNLGLSTHSAFSPLVASNLSPSLRSMTLSPSFEQVGYFSGSFSSFPRDPVTTRAAEDLSHLRSKLQNPSMSTEEARLRTSHAWPLMCLWPAEVAKAGLDDLGTADKVACVNCGVKLSNWEPKDNAMSEHRRHFPNCPFVENLMRDQPSFNVSNVTMQTHEARVKTFINWPTRIPVQPEQLADAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWIEHAKWFPRCEYLLRVKGGEFVSQVQARFPHLLWNSSCTTSDKPVDENMDPIIHFEPGESPSEDAIMMNTPVVKAALEMGFSRRLIKQTVQSKILATEENYKTVNDLVSELLTAEDEKREEEKERQFEEVASDDLSLIRKNRMALFQRLTSVLPILGSLLSAKVITELEHDVIKQTTQTPSQARELIDTVLVKGNAAASIFRNCLKDFDPVLYKDLFVEKSMKYVPTEDVSGLPMEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKECAPSLRKCPICRGTIKGTVRTFLS
Protein: Arginine permease CAN1 (Canavanine resistance protein 1) (P04817)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: High-affinity permease for arginine.
Subcellular location: Cell membrane {ECO:0000269|PubMed:12100990, ECO:0000269|PubMed:14551254, ECO:0000269|PubMed:21223946, ECO:0000269|PubMed:21880895, ECO:0000269|PubMed:37005249}; Multi-pass membrane protein {ECO:0000269|PubMed:21880895}. Endosome membrane {ECO:0000269|PubMed:21880895}; Multi-pass membrane protein {ECO:0000269|PubMed:21880895}. Note=Recycled via the retromer-mediated pathway (PubMed:21880895). Requires phosphatidyl ethanolamine (PE) for localization and exclusively associated with lipid rafts called MCCs (membrane compartment occupied by CAN1) (PubMed:12100990, PubMed:14551254, PubMed:21223946). {ECO:0000269|PubMed:12100990, ECO:0000269|PubMed:14551254, ECO:0000269|PubMed:21223946, ECO:0000269|PubMed:21880895}.
Interaction partners:
- Imidazoleglycerol-phosphate dehydratase
- N-
- Phosphoribosylaminoimidazole carboxylase
- Orotidine 5'-phosphate decarboxylase
- 3-isopropylmalate dehydrogenase
- Protein SUR7
- L-2-aminoadipate reductase
- DNA repair protein RAD5
- Saccharopepsin
- Uracil permease
Sequence:
MTNSKEDADIEEKHMYNEPVTTLFHDVEASQTHHRRGSIPLKDEKSKELYPLRSFPTRVNGEDTFSMEDGIGDEDEGEVQNAEVKRELKQRHIGMIALGGTIGTGLFIGLSTPLTNAGPVGALISYLFMGSLAYSVTQSLGEMATFIPVTSSFTVFSQRFLSPAFGAANGYMYWFSWAITFALELSVVGQVIQFWTYKVPLAAWISIFWVIITIMNLFPVKYYGEFEFWVASIKVLAIIGFLIYCFCMVCGAGVTGPVGFRYWRNPGAWGPGIISKDKNEGRFLGWVSSLINAAFTFQGTELVGITAGEAANPRKSVPRAIKKVVFRILTFYIGSLLFIGLLVPYNDPKLTQSTSYVSTSPFIIAIENSGTKVLPHIFNAVILTTIISAANSNIYVGSRILFGLSKNKLAPKFLSRTTKGGVPYIAVFVTAAFGALAYMETSTGGDKVFEWLLNITGVAGFFAWLFISISHIRFMQALKYRGISRDELPFKAKLMPGLAYYAATFMTIIIIIQGFTAFAPKFNGVSFAAAYISIFLFLAVWILFQCIFRCRFIWKIGDVDIDSDRRDIEAIVWEDHEPKTFWDKFWNVVA