wanglab/gogpt-training-data huggingface dataset:
Protein: TrwM protein (O50329)
Organism: Escherichia coli
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MKPPQQQHEAFPLFKGATRLPTILGEPMIPLMAMVMGVAVIALTVSIWWWALVPPLWFIMAQITKNDDKAFRIWWLWIDTKFRNRNKGFWGASSYSPANYRKRR
Protein: SD10848p (Q95TF7)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MRTHTQERPYKCPEDDCGKAFTASHHLKTHRRTHTGEKPYPCQEDSCQKSFSTSHSLKSHKKTHQRQLQNKGRKKRPLKTQQTKCSDQEQKDPQQEEQEEEEFIKEDQPEMTLLNPGSHCSETTSTDSGVVLQTLTPQDHLSNVFILQGNEPLILPETSQAYQLSYAAEEEIPSPWIDAGVLVSKPIIPMAPLTDACVALPTEMPSFVNLKPTFGNAVSGNMGDPQPETMDVDPTVETSLPTPTLELNQPNIEELLKQDSFENEEDMETESLLNDILMTIDNNSALLQATLQQASQVPSDASGLVELDIRDNKPTLKQITADAGICNCTNCKCDQTKSCHGGDCGAAAAQQTTRTGAPTTTTTTTTMNSSGGKRICGSVVPTKKVSKRETEMNQNIEDVALLLQNLASMSSGGSSGGGGGCCGGGAVKPAPSGGGCCGEPKAPKPVNNGCGCARPSAPSSAGCCGSGVASTPKPTGGCCSGNQKPAPTATAASSPSCCCSGKGEVQEPPVISSASSAPAAAVKGNACTCKSPAEGVANGCCVVICIKTLQALRKVLTRRNLNLMLCPQQN
Protein: Trypsin inhibitor 1 (JcTI-I) (C0HJF7)
Organism: Jatropha curcas (Barbados nut)
Function: Inhibits trypsin (IC(50)=1.25 uM) but not chymotrypsin or papain. Has antibacterial activity against S.enterica ATCC 10708 (MIC=5 ug/ml) and S.aureus ATCC 25923 (MIC=5 ug/ml) but not against B.subtilis ATCC 6633 or P.aeruginosa ATCC 25619. Has no hemolytic activity against human erythrocytes. Is not toxic to mice.
Interaction partners:
Sequence:
VRDICKKEAERQDLSSCENYITQRRGY
Protein: Sugiol synthase (EC 1.14.14.65) (Cytochrome P450 76AH3) (Ferruginol monooxygenase) (EC 1.14.14.60) (A0A0Y0GRS3)
Organism: Salvia miltiorrhiza (Chinese sage)
Function: Monooxygenase that oxidizes ferruginol to produce sugiol. Oxidizes ferruginol at C-12 to produce 11-hydroxyferruginol. Can oxidize 11-hydroxyferruginol to 11-hydroxysugiol. These products are intermediates in tanshinone biosynthesis.
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MDSFSLLAALFFISAATWFISSRRRRNLPPGPFPYPIVGNMLQLGAQPHETFAKLSKKYGPLMSVHLGSLYTVIVSSPEMAKEIMLKYGTVFSGRTVAQAVHACDHDKISMGFLPIGAEWRDMRKICKEQMFSHQSMEDSQGLRKQKLQQLLDHAHRCSEQGRAIDIREAAFITTLNLMSATLFSMQATEFDSKVTMEFKEIIEGVASIVGVPNFADYFPILRPFDPQGVKRRADVYFGRLLALIEGYLNDRIQSRKANPDAPKKDDFLETLVDILNSNDNKLKTDHLLHLMLDLFVGGSETSTTEIEWIMEELVAHPDKMAKVKAELKSVMGDEKVVDESLMPRLPYLQAVVKESMRLHPPGPLLLPRKAESDQVVNGYLIPKGTQVLINAWAMGRDSTIWNNPDAFQPERFLDNKIDFKGQDYELIPFGSGRRVCPGMPLANRMLHTVTATLVHNFDWKLERPDAPLAEHQGVLFGFAVRRAVPLRIVPYKA
Protein: Endonuclease G inhibitor, isoform A (Endonuclease G inhibitor, isoform B) (Endonuclease G inhibitor, isoform C) (SD16985p) (Q9V3V9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Endonuclease
Sequence:
MSKRKAEDTQSDKMATAEKVAQNDYTIGLVDPVKDYQKLIETRVQVDEIVDDDVTKENFDRTAAAARDVIWRLLFDEAGTSQSNTEKASQLLEEYRGDACFYDPTPYNEWIVKLRDEVLKKELLDFWRDVLVKKQLGPCWSRDSDLFDSDDTPPLEFYAHAGCTAPFAASLKVRAALEEQASLDQDGPATPTTPGELSADDAAALSGEFEATLTKENPLEEYRTLMKRFVLTKIIVPDSVHQASVKKIAAAAREIIWKLLFDGTPSAEDQNKAAELLQEYKGDAGFYGPDDYNSWIFNLRDEVLTKELLDFWRDKMVKMELGPSCARDSDYYDNEDPLPFEFYEKAGCKAPFEGPVNDD
Protein: ATPase subunit 9, putative (EC 3.6.3.14) (Q38C84)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- ATP synthase F1 subunit gamma protein, putative
- ATP synthase, epsilon chain, putative
- ATP synthase alpha chain
- ATP synthase subunit beta
- ATP synthase delta chain
- Uncharacterized protein
- V-type proton ATPase subunit a
- Uncharacterized protein
- Uncharacterized protein
- V-type proton ATPase subunit
Sequence:
MMRRLALQSSIRRATPFATPLVASTKALNPMCSAITIREASTVAISVQGLHYVGTGLAAIALAGVGLGIGTIFGNLLVACARQPNLTKMLFNYAILGFALTEAIGLFALMLAFLMLFS
Protein: C3H1-type domain-containing protein (Q57WV7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MMQRDTALWSPNVLTPGGGTQTGSTNPNGRGAATLTGGASPATATAGTNSYPYLASGSPSVLLSGSTNGMGGATTVPMPTTASTHERSQELCKYYVNGGCLRGAQCQYLHELPDERHLDVNGYGYILNPNVHNAQKTIPLAASNNTTGTVQVNGGAATTTSSLLVGLTPGGNRQIISSKGKTQAHLMVGVPYQIPTTTAKASPPKYRPPEPFLEYNLPPTLALPLKTSPEDVARQLTCAILQTGLH
Protein: Olfactory receptor 7G2 (OST260) (Olfactory receptor 19-13) (OR19-13) (Olfactory receptor OR19-6) (Q8NG99)
Organism: Homo sapiens (Human)
Function: Odorant receptor.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MEARNQTAISKFLLLGLIEDPELQPVLFSLFLSMYLVTILGNLLILLAVISDSHLHTPMYFFLSNLSFLDICLSTTTIPKMLVNIQAQNRSITYSGCLTQICFVLFFAGLENCLLAAMAYDRYVAICHPLRYTVIMNPRLCGLLILLSLLTSVVNALLLSLMVLRLSFCTDLEIPLFFCELAQVIQLTCSDTLINNILIYFAACIFGGVPLSGIILSYTQITSCVLRMPSASGKHKAVSTCGSHLSIVLLFYGAGLGVYISSVVTDSPRKTAVASVMYSVFPQMVNPFIYSLRNKDMKGTLRKFIGRIPSLLWCAICFGFRFLE
Protein: Brevican core protein (Brain-enriched hyaluronan-binding protein) (BEHAB) (Chondroitin sulfate proteoglycan 7) (Q96GW7)
Organism: Homo sapiens (Human)
Function: May play a role in the terminally differentiating and the adult nervous system during postnatal development. Could stabilize interactions between hyaluronan (HA) and brain proteoglycans.
Subcellular location: Secreted {ECO:0000269|PubMed:25326458, ECO:0000269|PubMed:37453717}.; SUBCELLULAR LOCATION: [Isoform 1]: Secreted, extracellular space, extracellular matrix.; SUBCELLULAR LOCATION: [Isoform 2]: Membrane; Lipid-anchor, GPI-anchor.
Interaction partners:
- Receptor-type tyrosine-protein phosphatase zeta
- Aggrecan core protein
- Versican core protein
- Neurocan core protein
- A disintegrin and metalloproteinase with thrombospondin motifs 5
- A disintegrin and metalloproteinase with thrombospondin motifs 4
- Agrin
- Decorin
- Basement membrane-specific heparan sulfate proteoglycan core protein
- Biglycan
Sequence:
MAQLFLPLLAALVLAQAPAALADVLEGDSSEDRAFRVRIAGDAPLQGVLGGALTIPCHVHYLRPPPSRRAVLGSPRVKWTFLSRGREAEVLVARGVRVKVNEAYRFRVALPAYPASLTDVSLALSELRPNDSGIYRCEVQHGIDDSSDAVEVKVKGVVFLYREGSARYAFSFSGAQEACARIGAHIATPEQLYAAYLGGYEQCDAGWLSDQTVRYPIQTPREACYGDMDGFPGVRNYGVVDPDDLYDVYCYAEDLNGELFLGDPPEKLTLEEARAYCQERGAEIATTGQLYAAWDGGLDHCSPGWLADGSVRYPIVTPSQRCGGGLPGVKTLFLFPNQTGFPNKHSRFNVYCFRDSAQPSAIPEASNPASNPASDGLEAIVTVTETLEELQLPQEATESESRGAIYSIPIMEDGGGGSSTPEDPAEAPRTLLEFETQSMVPPTGFSEEEGKALEEEEKYEDEEEKEEEEEEEEVEDEALWAWPSELSSPGPEASLPTEPAAQEESLSQAPARAVLQPGASPLPDGESEASRPPRVHGPPTETLPTPRERNLASPSPSTLVEAREVGEATGGPELSGVPRGESEETGSSEGAPSLLPATRAPEGTRELEAPSEDNSGRTAPAGTSVQAQPVLPTDSASRGGVAVVPASGDCVPSPCHNGGTCLEEEEGVRCLCLPGYGGDLCDVGLRFCNPGWDAFQGACYKHFSTRRSWEEAETQCRMYGAHLASISTPEEQDFINNRYREYQWIGLNDRTIEGDFLWSDGVPLLYENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVPCNYHLSYTCKMGLVSCGPPPELPLAQVFGRPRLRYEVDTVLRYRCREGLAQRNLPLIRCQENGRWEAPQISCVPRRPARALHPEEDPEGRQGRLLGRWKALLIPPSSPMPGP
Protein: Uga3p (A0A1D8PU36)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MIVTFNSRSQRKEGNKIDSDTTTTTTTTPTTAATGTTAVLTVKHEEEGSQKNVKHINGSKDYYKFKDGRSRNGCLTCKVRKKKCSEEKPVCNDCSRFGKNCIYITDSMTEQEIKDLKKSVELQERNHKLRKRKPKSKNSTESTKLATPDHTHLSDSISPVPRKKAKRSNKIDVEANTRVEDSSDPFKAFSYNSTLQTATNPSSPGPTIPPNSPAIQNLIHPAGSSEEQEFSPSKPQPHPENTTQETKSVEEIIRENGTESEVNSPSTFLTFLRDVNSSHNHNHHHQVGFLEDSGHNHVRGGHEIETDNDEDKIQTLDVDLDNPELREILTSPDFNGALESFENSSHPINGSNISYVDLISSLNLFLHHPQIPPSPTYIPELIDPTSSYLYNYYADVLSKKISIAPISQNESNSYQKVFLPLAHRDKGVLYAILAWSGFHLGGHWSEEGVKYLEYALDHLNKSMFDRPHHDRQMIVNMLATLMILCAAEICKGDVKNWSVYLHWGWKLLSNNGGILSFNKSKEEHWLISNFAYHDLLASSSSERGTYFPSEEYDFIFRDDDGFSLGNLNPLLGISKNLYRIIGDISTLLYESKKQLDIFYSREFTGTPPGVVEKLNNEDADGNVDDDDDCESQLSDHGKASQILLSVISKVKNLEKQIDESKPAAKDLVGLTDQELELQLTLFEAFQLSAKLFLRQSIMKCNPSMLESQVLNNDLIKCLDVLVGTSVQASLVFPIFISGIHCVSRHDQESMRHRINKFIKLYGLWNVCRVSFVLQKIWKDNPDGSKVVDWHNLLKELGWDINFA
Protein: Vasopressin-neurophysin 2-copeptin precursor (Vasotocin-neurophysin) (Q8AV79)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSDSLLSVCVLCVLALSTLSSACYIQNCPRGGKRSQPEPIRQCMSCGPGGVGRCFGPSICCGPGLGCVLGSPEAQVCMEEEQLSGPCETGGTSCGDRGGRCAAEGICCDSESCAVDPDCPEGSSAGLKSISGETLLRLLNLATRRQRPF
Protein: Solute carrier organic anion transporter family member 1A1 (Sodium-independent organic anion-transporting polypeptide 1) (OATP-1) (Solute carrier family 21 member 1) (Q9QXZ6)
Organism: Mus musculus (Mouse)
Function: Mediates the Na(+)-independent transport of organic anions such as steroid sulfate conjugates (dehydroepiandrosterone sulfate (DHEAS), 17-beta-glucuronosyl estradiol, estrone-3-sulfate), conjugated (taurocholate) and unconjugated (cholate) bile acids, prostaglandin E2 (PGE2) and L-thyroxine T4. Also capable of transporting sulfobromophthalein (BSP), ouabain and gadoxetate. Hydrogencarbonate/HCO3(-) acts as the probable counteranion that exchanges for organic anions (By similarity). Shows a pH-sensitive substrate specificity which may be ascribed to the protonation state of the binding site and leads to a stimulation of substrate transport in an acidic microenvironment (By similarity).
Subcellular location: Basolateral cell membrane {ECO:0000250|UniProtKB:P46720}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P46720}.
Interaction partners:
- Solute carrier family 22, member 30)
- Hepatic sodium/bile acid cotransporter
- Solute carrier family 22 member 7
- Bile salt export pump
- NADPH-dependent 3-keto-steroid reductase Hsd3b5
- Cytochrome P450 7B1
- Cytochrome P450 7A1
- ATP-binding cassette sub-family C member 2
Sequence:
MEETEKKVATQEGRFFSKMKVFLMSLTCAYLAKSLSGVYMNSMLTQIERQFGIPTSVVGFITGSFEIGNLLLIVFVSYFGRKLHRPIIIGVGCVVMGLGCFLMASPHFLMGRYKYETTISPTSNLSSNSFLCIENRTQTLKPTQDPTECVKEIKSLMWIYVLIGNTMRGIGETPIMPLGISYIEDFAKSENSPLYIGILEMGKIVGPIIGLLLGSFFARVYVDIGSVNTDDLTITPTDTRWVGAWWIGFLVCAGVNILTSIPFFFFPKTLPKKELQDNVDVTKYEKVEKHRERAKKENLGITKDFLPFMKSLCCNPIYMLFSLTSVLQINGFASTFTFLPKYLEQQYGKSTSEAVFLIGVYSLPPVCLGYLISGFIMKKFKITVKKAAYIAFGLSLSEYFIFLCNYLLTCDNFPVAGLTTSYKGVQHPLYGEKNVLADCNTRCSCLTDTWDPVCGDNGLAYMSACLAGCEKSVGTGTNMVFQNCSCIGSSGNSSAVLGLCKKGPECDNKLQYFLIKSVFSSFIFSLAAIPGYMVLLRCVKSEEKSIGVGLHAFFIRLLAGIPAPVYFGALIDRTCLHWGTLKCGQPGACRMYDINRFRHIYLGLPAAVRGSSFLPAVFILILMRKFHFPGDIHSPDTELAEMKLTEKESECTDVCRSPKVENDGELKTKL
Protein: T-box transcription factor TBX1-A (T-box protein 1-A) (Q8AX98)
Organism: Xenopus laevis (African clawed frog)
Function: Probable transcriptional regulator involved in developmental processes (By similarity). Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence (By similarity). Induces pre-placodal ectoderm (PPE) gene expression in regions where RIPPLY3 is absent. Plays a role in the formation of the anteroposterior (AP) axis during embryonic development; required to establish the posterolateral border of the pre-placodal ectoderm (PPE) acting downstream of the retinoic acid receptor (RAR) signaling.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}.
Interaction partners:
Sequence:
MISAISSPWLTQLSHFCDVAAFTANSLSSLNATGGYHLSPSPGDPYSQHEPHYEPCSASQHSYSFGHACPEPESGASSSSCASSTPGSGSTGSSSSNKAPVKKNPKVANINVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKIFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGSLPLMNAFARSRNPVSSPTQNGSDKDGDGRREYERDASGTPLHGDAAHQQLMSRVLSLSLPVPGGLVPLSTGRPSPPHELRLDPHSQGSEPLHHHPYKYPTSYDRYLGAKTRPAPYPLPTIRGHGYHHHHMNPAAANMYSGAGAPGSYEYGPR
Protein: Translocon-associated protein subunit beta (TRAP-beta) (Signal sequence receptor subunit beta) (SSR-beta) (Q9CPW5)
Organism: Mus musculus (Mouse)
Function: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
- Translocon-associated protein subunit gamma
- Translocon-associated protein subunit delta
- Translocon-associated protein subunit alpha
- Protein transport protein Sec61 subunit beta
- Inactive rhomboid protein 2
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
- Oligosaccharyltransferase complex subunit OSTC
- Protein transport protein Sec61 subunit beta
- Protein transport protein Sec61 subunit alpha isoform 1
- Cancer-associated gene 1 protein homolog
Sequence:
MRLLAVVVLALLAVSQAEEGARLLASKSLLNRYAVEGRDLTLQYNIYNVGSSAALDVELSDDSFPPEDFGIVSGMLNVKWDRIAPASNVSHTVVLRPLKAGYFNFTSATITYLAQEDGPVVIGSTSAPGQGGILAQREFDRRFSPHFLDWAAFGVMTLPSIGIPLLLWYSSKRKYDTPKPKKN
Protein: Sidoreflexin (Q5APF5)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Mitochondrion membrane {ECO:0000256|ARBA:ARBA00004225, ECO:0000256|RuleBase:RU362000}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004225, ECO:0000256|RuleBase:RU362000}.
Interaction partners:
Sequence:
MASSIPGPVSLPQSKYDLTTYWGRVKHCAEISDPTMLLNTTHDIETAKRMVWDYKNGVTSKMSPELWRAKKVLDSTLHPDTGETVFLPFRMSSCVLSNLVVTAGMLTPNLGTAGTLFWQIANQSLNVAINTANANKSHPLTTKQIVTNYTLAVSASCSVALGLNSLVPRLKSLKPNTRMILGRLVPFAAVVSAGIVNVFLMRSEELKKGITVFDRKGNEVGTSKQAAWYAVGETAASRVINATPIMVIPPLILVKLQQSRFLKSKSKGVETLVNIGLIFATSLVALPFALAVFPQRRVLAVNKLESKFHELKDKDGNDIKELEFNRGI
Protein: Uncharacterized protein (A0A178VU28)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MWTVKPAAMPVQFHMRPTVATSVAYSQPPPHNYDGIHRRFINVPTKSQTSESVGGLGQQILLRTVDSNPRKPIPKETEISGSDVLWAIQRATAQRKRTNAGKKKTKNRLSGVELSSSAGEPTGDNGVDYSNVTPLRIKSDWGHRLEEFEKLLKEFQNTEL
Protein: Phenazine biosynthesis protein PhzD1 (2-amino-4-deoxychorismate hydrolase) (EC 3.3.2.15) (Isochorismatase) (Trans-2,3-dihydro-3-hydroxyanthranilic acid synthase) (P0DPB9)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule. PhzD1 (operon phzA1B1C1E1F1G1) has a role in the biosynthesis of the phenazine during planktonic growth. Catalyzes the hydrolysis of the vinyl ether functional group of 2-amino-2-deoxyisochorismate (ADIC), yielding pyruvate and trans-2,3-dihydro-3-hydroxyanthranilic acid (DHHA). Also able to act on isochorismate, chorismate and 4-amino-4-deoxychorismate (ADC) as substrates.
Interaction partners:
- anthranilate synthase
- Trans-2,3-dihydro-3-hydroxyanthranilate isomerase
- Probable non-ribosomal peptide synthetase
- Probable pyridoxamine 5'-phosphate oxidase
- Phospho-2-dehydro-3-deoxyheptonate aldolase
- Pyochelin synthase PchD
- 5-methylphenazine-1-carboxylate 1-monooxygenase
- Pyoverdine synthetase D
- Phenazine biosynthesis protein PhzB1
- Phenazine biosynthesis protein PhzA1
Sequence:
MSGIPEITAYPLPTAQQLPANLARWSLEPRRAVLLVHDMQRYFLRPLPESLRAGLVANAARLRRWCVEQGVQIAYTAQPGSMTEEQRGLLKDFWGPGMRASPADREVVEELAPGPDDWLLTKWRYSAFFHSDLLQRMRAAGRDQLVLCGVYAHVGVLISTVDAYSNDIQPFLVADAIADFSEAHHRMALEYAASRCAMVVTTDEVLE
Protein: Ovalbumin-related protein Y (Gene Y protein) (P01014)
Organism: Gallus gallus (Chicken)
Subcellular location: Secreted {ECO:0000269|PubMed:16428832}.
Interaction partners:
- Protein TENP
Sequence:
MDSISVTNAKFCFDVFNEMKVHHVNENILYCPLSILTALAMVYLGARGNTESQMKKVLHFDSITGAGSTTDSQCGSSEYVHNLFKELLSEITRPNATYSLEIADKLYVDKTFSVLPEYLSCARKFYTGGVEEVNFKTAAEEARQLINSWVEKETNGQIKDLLVSSSIDFGTTMVFINTIYFKGIWKIAFNTEDTREMPFSMTKEESKPVQMMCMNNSFNVATLPAEKMKILELPYASGDLSMLVLLPDEVSGLERIEKTINFDKLREWTSTNAMAKKSMKVYLPRMKIEEKYNLTSILMALGMTDLFSRSANLTGISSVDNLMISDAVHGVFMEVNEEGTEATGSTGAIGNIKHSLELEEFRADHPFLFFIRYNPTNAILFFGRYWSP
Protein: ADP-ribosylation factor-like 5 (LD31204p) (Q9VSG8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Vacuolar protein sorting-associated protein 52 homolog
- Vacuolar protein sorting-associated protein 53 homolog
- Vacuolar protein sorting-associated protein 51 homolog
- Vacuolar protein sorting-associated protein 54
- non-specific serine/threonine protein kinase
Sequence:
MGLLLSRLWRMFGNEEHKLVMVGLDNAGKTTILYQFLMNEVVHTSPTIGSNVEEVVWRNIHFLVWDLGGQQSLRAAWSTYYTNTELVIMVIDSTDRERLAVTREELYRMLQHEDLSKASLLVYANKQDLKGSMSAAEISRQLDLTSIKKHQWHIQACCALTGEGLYQGLEWIVQRIKNK
Protein: Odorant receptor 45b (Q9V589)
Organism: Drosophila melanogaster (Fruit fly)
Function: Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates. The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration. May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability. Involved in the behavioral responses to anisole.
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Odorant receptor 74a
- Odorant receptor 83a
- Odorant receptor 94a
- Odorant receptor 59a
- Odorant receptor 35a
- Odorant receptor 94b
- Odorant receptor 1a
Sequence:
MYPRFLSRNYPLAKHLFFVTRYSFGLLGLRFGKEQSWLHLLWLVFNFVNLAHCCQAEFVFGWSHLRTSPVDAMDAFCPLACSFTTLFKLGWMWWRRQEVADLMDRIRLLIGEQEKREDSRRKVAQRSYYLMVTRCGMLVFTLGSITTGAFVLRSLWEMWVRRHQEFKFDMPFRMLFHDFAHRMPWFPVFYLYSTWSGQVTVYAFAGTDGFFFGFTLYMAFLLQALRYDIQDALKPIRDPSLRESKICCQRLADIVDRHNEIEKIVKEFSGIMAAPTFVHFVSASLVIATSVIDILLYSGYNIIRYVVYTFTVSSAIFLYCYGGTEMSTESLSLGEAAYSSAWYTWDRETRRRVFLIILRAQRPITVRVPFFAPSLPVFTSVIKFTGSIVALAKTIL
Protein: Haloacid dehalogenase-like hydrolase domain-containing protein 3 (Q9CYW4)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MAHRLQMRLLTWDVKDTLIKLRRPVGEEYASKARAHGVVVEDITVEQAFRQAYRAQSHNFPNYGLSRGLTSRQWWKDVVLHTFRLAGVPDAQAMTPVADQLYEDFSSPFTWQVLEGAEMTLKGCRKRGLKLAVVSNFDRRLEDILTGLGLREHFDFVLTSEAVGCPKPDPRIFREALQRACVEPAVAAHVGDSYLCDYQGSQAVGMHSFLVAGSEPLDSAVRDSVPKEHILPSLSHLLPALDLLEASSPMS
Protein: tRNA (pseudouridine(54)-N(1))-methyltransferase (EC 2.1.1.257) (Q59034)
Organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
Function: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00587}.
Interaction partners:
- tRNA pseudouridine synthase Pus10
- Ribosomal RNA small subunit methyltransferase Nep1
- tRNA
- Uncharacterized protein MJ1638
- Flagella accessory protein J
Sequence:
MREFIFKANKTITSSDINLKDLPGSCGRLDLLCRCVSDAFFLSHDIRRDVVFYAVLYGQPNPPVCIKFVGSELKKVSPDERNIAIFIKKALKKFEELDEEQRKDWNQSTPGIYVRRLGFRNLVLEKLEEGKNIYYLHMNGEDVENVDIENPVFIIGDHIGIGEEDERFLDEIKAKRISLSPLELHANHCITIIHNVLDKKRICEI
Protein: MLO-like protein 7 (AtMlo7) (Protein NORTIA) (O22752)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in modulation of pathogen defense and leaf cell death. Activity seems to be regulated by Ca(2+)-dependent calmodulin binding and seems not to require heterotrimeric G proteins (By similarity). Controls pollen tube reception in the female gametophyte synergids.
Subcellular location: Cell membrane {ECO:0000269|PubMed:21071669}; Multi-pass membrane protein {ECO:0000269|PubMed:21071669}. Endomembrane system {ECO:0000269|PubMed:21071669}. Note=In synergids of unfertilized mature female gametophytes, present in a punctate pattern of endomembranes throughout the cytoplasm. Become polarly localized to the basal half of the synergids, to the filiform apparatus, upon pollen tube arrival at the micropyle. This relocalization upon fertilization requires FER.
Interaction partners:
- GPI-anchored protein LORELEI
Sequence:
MITRSRCRRSLLWFLVFHGGATATGAPSGGKELSQTPTWAVAVVCTFLILISHLLEKGLQRLANWLWKKHKNSLLEALEKIKAELMILGFISLLLTFGEPYILKICVPRKAALSMLPCLSEDTVLFQKLAPSSLSRHLLAAGDTSINCKQGSEPLITLKGLHQLHILLFFLAIFHIVYSLITMMLSRLKIRGWKKWEQETLSNDYEFSIDHSRLRLTHETSFVREHTSFWTTTPFFFYVGCFFRQFFVSVERTDYLTLRHGFISAHLAPGRKFNFQRYIKRSLEDDFKLVVGISPVLWASFVIFLLFNVNGWRTLFWASIPPLLIILAVGTKLQAIMATMALEIVETHAVVQGMPLVQGSDRYFWFDCPQLLLHLIHFALFQNAFQITHFFWIWYSFGLKSCFHKDFNLVVSKLFLCLGALILCSYITLPLYALVTQMGSHMKKAVFDEQMAKALKKWHKDIKLKKGKARKLPSKTLGVSESFSLSSSSSATTLHRSKTTGHSSNIIYYKQEDEEDEMSDLEAGAEDAIDRIQQQEMQFHNS
Protein: Rolling pebbles, isoform H (M9PI28)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Postsynapse {ECO:0000256|ARBA:ARBA00034110}.
Interaction partners:
Sequence:
MFPLTNRSSSGNRTNNNPSNNNNNQTTSFIIGGTTNINNNNNQLGGTNSAKDKGNFENNWSCNKTTGRRSGSGNSCSFLDLQSIRRLLEHDASGSVCPSCRISFDKGKRRKLIDTCGHERCYSCMFRNDQCPMCMNSSLKDVDGANAQGYDTGIGGSTSTIVSPLGSPQPQLRSHAQRNAALARYMQHRQESQSPDYHHRYASNGKLPRAAALSTNGNGFTTGTTQTVTVDVHHQLGGGGGGAAAAAKQLMANGISGHSRSSSMSHNIHAAAYSELSAAPPAFATPPTRRRFFNHKNLRSALTGGSGGGSGVGGGVGGAGGVGGGHRRTASNGGCPIDTASILSGGSDAIDHHSSFLNEKLQKDQLHARLGLLLNDPGSNGNSSSSGSGCEPISAHSTTSTTSSSGVGAASTTTSGSSQNVSPEQTLASGAGMLSGSQLSVATSHGVKEDALSLCGKFKAGCSMLHVYEALPSKSRKGNVRRSTRGQQGSSSSASAASAVGSRVTASSLAAVQLALKPLFFEVPLQEPDPPYVGRQWLVQQLSNILLGTETRVVLINGQPGTGKTAFCLQLVEYSCFGRRQMQDDPDGIYSQLQLGAHCERMRGLASHMVGYHFCQADANLTCQVPDFVHSLAAQLCQAPQLTAYRDYLLSEPHLQDILSVRECIADAERVMKLAILEPLAHLHRAGKIPAKVAVIVVDALCEAEYHRPDHGHTIASFLAQLTPHFPAWLKLVATVRTQMLELVKAPSYTQLTLDSWASSQALQQDMLDYIGARLADSPEIRMNIGGGGGQNSQSGSQPQTKFVSHLQSLSRGSMLYAKLILDLIARGQLVIKSSSYKVLPVSLAQIFLLHFNLRFPTARSFEQAAPILNICLAALYPLTLDEIYYSMEALSHGREALSWPDFMQRFKLLDGFLIKRLDNTYMFFHSSLREWLMRRDEGESNKFLCDARLGHAGIAFRLSRLQAPLSPQLTLELGHHMLKAHLYGGTSLTLLSPRDLQSYWLAGAADNISSSLGALRNVYSPNLKVSRLVLLAGASPNHRTDYMGGAPILCIAAHEGILPMVSLLLEFGADVGLTNSQGCTPLILAAMRGHCDVVRPLVAAGSSLGQLDITQRCALVHAARMGHLSVVKYLLACDWSPRPHSQDVTRSVALQQALIGAAAQAHCKILEDLLDLNETEFDLDVNGMEPSSGELALTAAARHGCIDVVGILLSRGAQIDARNRQGYSALWLAVKEGHWSVVEHLLQRGALLDEPLGQTRKTPLMIAAEEGHLELVDLLLARGAQREAQDHEGFTALSWACLRGHLAAAKTLIEHGCNRHHEDHNGRTALDLAAYQGAASLVIYILEQGGNLEHIDVHGMRPLDRAIACRNIQAVQVFLRKGAKLGPTTWSMAMGKPEILVILLNKLLEDGNVLYRKNRFQEAAHRYQYALRKISGLEQLLERNAIFAQLRTNLLLNLSRCKRKLNELDASIDLATQAIAQKPHSYEGYYARAKARMELGALNEALVDANEAMQQAAQSGVLCEVVEVLKRIQTELLTRISISSEDQTGRMSNIGGGASVAYESHHEITDL
Protein: Protein capicua homolog (Q96RK0)
Organism: Homo sapiens (Human)
Function: Transcriptional repressor which plays a role in development of the central nervous system (CNS). In concert with ATXN1 and ATXN1L, involved in brain development.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}.
Interaction partners:
- Ataxin-1
- Ataxin-1-like
- Splicing factor 45
Sequence:
MKPMKKACTGLSGPGSGSKSPPATRAKALRRRGAGEGDKPEEEDDEAQQPQPQSGPEEAEEGEEEEAERGPGAEGPPLELHPGDPAPGPAEDPKGDGEAGRWEPSLSRKTATFKSRAPKKKYVEEHGAGSSGVAGAPEERVRTPEEASGLGVPPRPPTSTRSSSTDTASEHSADLEDEPAEACGPGPWPPGSTSGSYDLRQLRSQRVLARRGDGLFLPAVVRQVRRSQDLGVQFPGDRALTFYEGVPGAGVDVVLDATPPPGALVVGTAVCTCVEPGVAAYREGVVVEVATKPAAYKVRLSPGPSSQPGLPGSLPQPPQPLHREPEEAVWVARSSLRLLRPPWEPETMLRKPPTGPEEEQAEPGATLPPCPAALDPKQPEDAEVSKISFGGNLGTHCEEGEEKHPPALGTPALLPLPPPQLLSPPPKSPAFVGPGRPGEQPSPCQEGSQGGSRSSSVASLEKGTAPAARARTPLTAAQQKYKKGDVVCTPSGIRKKFNGKQWRRLCSRDGCMKESQRRGYCSRHLSMRTKEMEGLADSGPGGAGRPAAVAAREGSTEFDWGDETSRDSEASSVAARGDSRPRLVAPADLSRFEFDECEAAVMLVSLGSSRSGTPSFSPVSTQSPFSPAPSPSPSPLFGFRPANFSPINASPVIQRTAVRSRHLSASTPKAGVLTPPDLGPHPPPPAPRERHSSGILPTFQTNLTFTVPISPGRRKTELLPHPGALGAPGAGGGGAAPDFPKSDSLDSGVDSVSHTPTPSTPAGFRAVSPAVPFSRSRQPSPLLLLPPPAGLTSDPGPSVRRVPAVQRDSPVIVRNPDVPLPSKFPGEVGTAGEVRAGGPGRGCRETPVPPGVASGKPGLPPPLPAPVPITVPPAAPTAVAQPMPAFGLASSPFQPVAFHPSPAALLPVLVPSSYTSHPAPKKEVIMGRPGTVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKAPGSSSCGAERLHTVGGPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYSGPKPSTQYGAPGPFAAPGEGGALAATGRPPLLPTRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGNKGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAATGR