wanglab/gogpt-training-data huggingface dataset:
Protein: Protein 33K (L4-33K) (Splicing factor 33K) (Terminase, small subunit) (P24940)
Organism: Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)
Function: Promotes alternative splicing of late transcripts by promoting splicing at weak 3' splice sites. Required for the temporal activation of major late pre-mRNA splicing at late times of infection. Induces the splicing and expression of the late capsid vertex protein.
Subcellular location: Host nucleus {ECO:0000269|PubMed:22944109, ECO:0000269|PubMed:23388198}. Note=At late time of infection, reorganized from the nuclear margin to ring-like structures at viral replication centers. {ECO:0000269|PubMed:22944109}.
Interaction partners:
Sequence:
MAPKKKLQLPPPPTDEEEYWDSQAEEVLDEEEEDMMEDWESLDEEASEVEEVSDETPSPSVAFPSPAPQKSATGSSMATTSAPQAPPALPVRRPNRRWDTTGTRAAHTAPAAAAAAATAAATQKQRRPDSKTLTKPKKSTAAAAAGGGALRLAPNEPVSTRELRNRIFPTLYAIFQQSRGQEQELKIKNRSLRSLTRSCLYHKSEDQLRRTLEDAEALFSKYCALTLKD
Protein: Low-density lipoprotein receptor-related protein 10 (LRP-10) (Q7TQH7)
Organism: Mus musculus (Mouse)
Function: Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction. May be involved in the uptake of lipoprotein APOE in liver.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Membrane, coated pit {ECO:0000250}.
Interaction partners:
Sequence:
MLSALPLLFLLLGGALARPDRITFPRSACEAPPAVLSEVQGTLQRPLGRDSRSSPANCTWVILGSKDQTVTVRFQKLHLACGSEHLILHSPLQPPISLCEAPSGPLQLPGGNVTITYSYAGARAPMGQGFLLTYSQDWLLCLQEEFQCLNHRCIPAAQRCDGIDACGDGSDEAGCSSDPFPNLNPAPAPTLACNLTLEDFYGVFSSPGYSHLASVSHPQSCLWLLDPHDGRRLAVRFTALDLSYGDAVHVYDGAGPPETPRLLRSLTHFSNGKAVTVETLSGQAVVSYHTVAWSSGRGFNATYHVRGYCLPWDRPCGLGSGLGASENLGERCYSEAQRCDGSWDCADGTDEEGCPGCPPGHFPCGAAGTPGATACYLPADRCNYQTFCADGADERRCRHCQPGNFRCRDEKCVYETWVCDGQPDCTDGSDEWDCSYALPRKVITAAVIGSLVCGLLLVIALGCTCKLYAIRTQEYSIFAPLSRMEAEIVQQQAPPSYGQLIAQGAIPPVEDFPTENPNDNSVLGNLRSLLQILRQDMTPGGTSGGRRRQRGRSIRRLVRRLRRWGLLPRTNTPARAPETRSQVTPSVPSEALDDSTGQACEGGAVGGQDGEQAPPLPIKTPIPTPSTLPALATVSEPPGPLPSVPVESSLLSGVVQVLRGRLLPSLWSPGPTWTQTGTHTTVLSPEDEDDVLLLPLAEPEVWVVEAEDEPLLA
Protein: Protein vav (DroVav) (dVAV) (Q9NHV9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases. Probably plays a pivotal role as a signal transducer protein during fruit fly development.
Interaction partners:
- Growth factor receptor-bound protein 2
- E3 ubiquitin-protein ligase CBL
- Ras-related protein Rac1
- RH14395p
- Epidermal growth factor receptor
- Tyrosine-protein kinase Btk
- Ras-like GTP-binding protein Rho1
- AT17867p
- Cdc42 homolog
- Ras-related protein Rac2
Sequence:
MASSSSSNSFGGVAGVNGDLWRECVAWLTRCKVIPPDHKAAQPDAEIRILAMTLRDGVLLCNLVIHLDPSSLDPREFNRKPQMAQFLCSKNIKLFLDVCHNNFGIRDADLFEPTMLYDLTNFHRVLITLSKLSQCRKVQQLHPDLIGFNLQLSPTERSHSDEAIYKDLHSTTTDNIACNGTGYDHTNTKEEEVYQDLCALHRTSRSQTASSTSFEQRDYVIRELIDTESNYLDVLTALKTKFMGPLERHLNQDELRLIFPRIRELVDIHTKFLDKLRESLTPNAKVKMAQVFLDFREPFLIYGEFCSLLLGAIDYLADVCKKNQIIDQLVQKCERDYNVGKLQLRDILSVPMQRILKYHLLLDKLVKETSPLHDDYRSLERAKEAMIDVSQYINEVKRDSDHLVIIQKVKDSICDIHLLQNGNGSDLLQYGRLLLDGELHIKAHEDQKTKLRYAFVFDKILIMVKALHIKTGDMQYTYRDSHNLADYRVEQSHSRRTIGRDTRFKYQLLLARKSGKTAFTLYLKSEHERDKWRKALTEAMESLEPPGCQSTDHKMEIYTFDAPTTCRHCSKFLKGRIHQGYRCKVCQISVHKGCISSTGRCKQNPVSVPPPVCDRQLSEFNWFAGNMDRETAAHRLENRRIGTYLLRVRPQGPSTAHETMYALSLKTDDNVIKHMKINQENSGDSMLYCLSSRRHFKTIVELVSYYERNDLGENFAGLNQSLQWPYKEVIATALYDYEPKAGSNQLQLRTDCQVLVIGKDGDSKGWWRGKIGDTVGYFPKEYVQEQKLASEEL
Protein: GDI interacting protein 3, isoform B (GDI interacting protein 3, isoform D) (GDI interacting protein 3, isoform E) (LD37137p) (MIP06640p) (Q7K0S5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- UBX domain-containing protein 4
- Transitional endoplasmic reticulum ATPase TER94
- GH01724p
- Uncharacterized protein
- GM09977p
- Small VCP interacting protein, isoform A
- Caspar, isoform A
- GH28815p
- UBX domain-containing protein 7
Sequence:
MSKIKKFFSRKKAEAAFKLNLTGSGMGTGHKLNSPKQETPSSSSRQKYEAYVPPKRNEISNEARAAASAALARIDKKTSREFNTSLSAVKAQAKRELEAERRQREEAMGTPSTTSTSTSASGGDTRNLACEGVFFRCPLISEEILPKSVWKVRIKEFLYQQLEADRGLTACLIIHNCNVKEKADECIATLIRYLENLIKNPEEEKFCKIRMSNKIFSEKVRYVEGALDVLQAAGFNEVQIDGEPFLLWTKEQTEKDLDLPTLVEALKSSEIIPLELDRNIKVLLPSQACRVALPDEFYRLSPEEIKKEQQLRSEAIAQSQMLRTKAMREREEQRNLRMYRYALVRVKFPNGLFIQGTFNVYEKISDVFEFVQSCLADESLDFSLVSNSDGKLGDEDLEKTLYDCKLIPNTLLLFSANDTPAPLQTDINYLKEDLLMLVQAM
Protein: FUS RNA-binding protein (RNA-binding protein FUS) (F1R0M4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- TAR DNA-binding protein 43
- Guanine nucleotide exchange C9orf72 homolog
- Superoxide dismutase
- TAF15 RNA polymerase II, TATA box-binding protein
- Ataxin-2
- Transitional endoplasmic reticulum ATPase
- Drosha ribonuclease III.
- VAMP-associated protein B and C
- Senataxin.
- Cytotoxic granule associated RNA binding protein TIA1
Sequence:
MASNDYGQTSSHGYGGYGGQSGQSYSQPSAQNYSQQSYGGYNQSSESSSAPYNQGGYSSNYGQSQSGGYGSQAPSQGYSQSSQSYSSGGYSNTSQPPPAQSGGYSQQSSYSGYNQSSPASAPGGYSSSSQSSGYGQQQQQSGGGYGGSGGQSGGYGSSGGQSSGFGGSGGQHQSSQSGGGSYSPSPNYSSPPPQSYGQQSQYGQGGYNQDSPPMSGGGGGGGYGGQDGGYSQDGRGGRGRGGGFGGRGAGGFDRGGRGGPRGRGGMGMGDRGGFNKFGGPRDHGAGGPNMQEQDNSDNNTIFVQGLGDDYTVDSVADYFKQIGIIKVNKKTGLPMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKDFNGNPIKVSFATRRAEFGRGGSSGGMRGGRGRGGPMGRGGFGGGRGGGGGGGGFQGNNGGGSGNGGGQQRAGDWKCSNPSCGNLNFSWRNECNQCKEPKPEGSGGGMSPMGGGFGGERGRSGFDRGGFRGRGGDRGGFRGGRGGDRGGFGPGKMDSRGDHRHDRRDRPY
Protein: 4-hydroxyphenylpyruvate dioxygenase (C8VKK0)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Homogentisate 1,2-dioxygenase
- homogentisate 1,2-dioxygenase
- homogentisate 1,2-dioxygenase
- Aspartate aminotransferase
- aspartate transaminase
- Aspartate aminotransferase
- histidinol-phosphate transaminase
- Aromatic-amino-acid transaminase, hypothetical
- aromatic-amino-acid transaminase
- Xylose isomerase-like TIM barrel domain-containing protein
Sequence:
MAPSAIDPPTSTSLPSSISSYRGYDHVHWYVGNAKQAASYYITRMGFKRIAYRGLETNSRAICSHVIRNGDITFVLTSPLRSLDQISRFTPEEQDLLREIHHHLEQHGDAVKDVAFEVDSVDAVFNAAVANGAKVVKGLTTVEDENGKVTMATIQTYGQTTHTLIERGAYRGTFLPGYRVETSLEDPISALLPGVLLNRIDHCVGNQDWNEMDKICEYYEKALGFHRFWSVDDKQICTEFSALKSIVMASPNDIVKMPINEPAKGKKQSQIEEYVDFYNGAGVQHIALLTDDIIRDITNLKARGVEFIKVPDTYYEDIKIRLKKAGLTLHEDFETIRALDILIDFDENGYLLQLFTKHLMDRPTVFIEIIQRHNFSGFGAGNFKSLFEAIEREQALRGNLV
Protein: Metallo-beta-lactamase family protein (Q727T9)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- Glycolate oxidase, subunit GlcD, putative
- Nitroreductase family protein
- Pyridine nucleotide-disulfide oxidoreductase
- Rhodanese-like domain protein
Sequence:
MPIKTFPLGPLETNCHLVHNGRTAVVVDPGGAPRPVLNYLEMQGLTLTHILNTHLHFDHIYGNAALAAATGAPILASAGDAFLRQTELGKGGAFGFPAVDDFTSIDLEPGEHRFGDLACTAFATPGHTPGSLSFYFPEEDTIIVGDLIFYRSIGRTDFPGGDLEKLRASVRDHIFTLPGKTRILPGHGPATSVDDETRNNPYFGDFAV
Protein: Neuropeptides B/W receptor type 1 (G-protein coupled receptor 7) (Q8MJV3)
Organism: Bos taurus (Bovine)
Function: Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals (By similarity).
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Neuropeptide B
- Neuropeptides B/W receptor type 2
- Prepronociceptin
- Uncharacterized protein.
Sequence:
MHNASYWGPERANTSCPAPAPTLGCPNASGPAPPLPPPLAVAVPVVYAVICAVGLAGNSAVLFVLLRAPRRKTVTNLFILNLAVADELFTLVPPVNIADFLLRRWPFGELLCKLVVAVDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYGAARAVSLAVWGVATLVVLPFAVFARLDEEQGRRQCVLVFPQPEALWWRASRLYTLVLGFAIPVSTICVLYTSLLCRLRAIRLDSHAKALDRAKKRVTVLVVAILAVCLLVWTPYHLSTVVALTTDLPQTPLVIAVSYFITSLSYANSCLNPFLYAFLDDSFRRSLRQLLACRTTS
Protein: Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger) (Solute carrier family 24 member 1) (Q9IAL8)
Organism: Gallus gallus (Chicken)
Function: Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q28139}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Cyclic nucleotide-gated channel rod photoreceptor subunit alpha
- Phosphodiesterase
- Uncharacterized protein.
- Uncharacterized protein
Sequence:
MHLPRRRRLQRNRIFFFLAVVSLLSVYQLQFSPSAIPALLTAHQHEDPVKVTSREPFRNKTSKTGNVTAAPKIRHCVYIDPEPTVPITASEDTTQRENVNESYPDEKPVYESKGEYPQDLFSVEERRQGWVVLHIFGMMYVFVALAIVCDEYFVPALGVITEKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCALFSREILHLTWWPLFRDISFYIVDLLMLILFFLDSVIDWWESLLLLTAYATYVFTMKHNVSLEQWVKEELSKKLNAVQAASAEHMRKKSSVAVAEDGTKPADGKKLQPTTALQRGTSSASLHNSQMRSTIFQLMIHTLDPLAGAKFKDRVDILSNIAKVKADSLTGQGTKPEAEEEKQASQNTVQVTPASDSEPSKDKQKEDTPQDGQPPSDSDNSEDSSSDSEDDSDDDSTDDEENDEPLSLEWPETRKKQAIYLFLFPIVFPLWSTIPDVRNPDSKKFFVITFFGSIIWIAAFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWFLYSVFNGFSPVAVSSNGLFCAIVLLFLMLLFVIISIALCKWKMNKILGVTMFALYFVFLIISVMLEDRIISCPVSV
Protein: Protein kinase domain-containing protein ppk32 (Q9P7X5)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Protein kinase domain-containing protein ppk3
- Repressor of RNA polymerase III transcription maf1
- Putative coatomer subunit alpha
Sequence:
MLANALRLVSNSKKIKYDYDIQKENSVQVGPWTVYSASKKGTNEEVSVFTFDKKNLSTLLKRGSIDSNLKTNYVLELLRKDVSSLSRLRHPSLLQVVEPLEESKSSMSFVTRRIQSMLQDFIKSSNGGFSNYGSSANGKSSGNALEEVEIQKGLLQIIDGLVFLHGSAKVIHYNIRPSSVVVDAKGDWKLCGFSFSQSVESARYEFNDYDFGIPSSLQQSMDFLAPEYITHEIAGPESDVFSFGCLIYSIFNKNQSIINANNHLLSYEKEITSLNSPTFIESKNLPSENLKSLLKETLAVDPKQRASMFELERSPYFTGSAIAALRFLESFPEKLPSEKVSFMESLSKNLTTFPYRIQSQKILPTLLDHLNDQKLVPSLLPCIFEISKGLDSSIFSSKVFTAIFPIISAANSYPERVPLCIFQYMDCLKSKLPSGEFLSKIVPFIYGCFENSSLNVQTTSIQILGTLLDIIDVTTVKSSICPKLYHSFSVTNQLDVKVAILDTFNVFINQKFLDSFAIVDKLLPVLEKVKTREPTVVMGMVTVYISAGAIIPEETVHEQVIPRLWILSVSPSLSLEQYNKCMREIRSLSDAVQKSHAKKLQSKPSSVVPNRITTDPFSSQTKEATSKPSSISPNKATTNIFTSQASLSSQGVARETSSASSYRSYSQRASTPAVTAKSSFHYATPTSGLSNFNSVTPSSSASLYPPLIPSEARTPSVQPANRRVTTPVVNQNTVTSDSSNDLGGWKSLL
Protein: Defective proboscis extension response 10, isoform D (M9PF17)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLTLWTALFCCLTGLAVCYQRQSVSNNNHNNAEAKPTHAPPSHYPHGHKWNEPYFDLTMPRNITSLVGKSAYLGCRVKHLGNKTVAWIRHRDLHILTVGTYTYTTDQRFQTSYHRDIDEWTLQIKWAQQRDAGVYECQISTQPVRSYSVNLNIVVPTATILGGPDLYVDKGSTINLTCIIKFSPEPPTHIFWYHQDKVLSEETSGGRLKFKTIKSEETKSILLIYDADLLHSGKYSCYPSNTEIASIRVHVLQGERPEAMQTNAAPAAVALACWSCHFGQATQAVRVISTMVAALVLLEACSSLLLQSGGGGGCPGGGSPAGGMPTRVREIREKPLTNSLLDPKIPSTTSAERVNNGSRNAR
Protein: Sensor histidine kinase RcsC (EC 2.7.13.3) (Capsular synthesis regulator component C) (P0DMC5)
Organism: Escherichia coli (strain K12)
Function: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane-associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. RcsC has also phosphatase activity. The system controls expression of genes involved in colanic acid capsule synthesis, biofilm formation and cell division.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_00979, ECO:0000269|PubMed:15919996, ECO:0000269|PubMed:2404948}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00979, ECO:0000269|PubMed:15919996, ECO:0000269|PubMed:2404948}.
Interaction partners:
- Phosphotransferase RcsD
- Outer membrane lipoprotein RcsF
- Transcriptional regulatory protein RcsB
- Transcriptional regulatory protein RcsA
- Aerobic respiration control sensor protein ArcB
- Putative membrane protein IgaA homolog
- Sensor protein EvgS
- Signal transduction histidine-protein kinase BarA
- Sensor protein TorS
- Sensor protein PhoQ
Sequence:
MKYLASFRTTLKASRYMFRALALVLWLLIAFSSVFYIVNALHQRESEIRQEFNLSSDQAQRFIQRTSDVMKELKYIAENRLSAENGVLSPRGRETQADVPAFEPLFADSDCSAMSNTWRGSLESLAWFMRYWRDNFSAAYDLNRVFLIGSDNLCMANFGLRDMPVERDTALKALHERINKYRNAPQDDSGSNLYWISEGPRPGVGYFYALTPVYLANRLQALLGVEQTIRMENFFLPGTLPMGVTILDENGHTLISLTGPESKIKGDPRWMQERSWFGYTEGFRELVLKKNLPPSSLSIVYSVPVDKVLERIRMLILNAILLNVLAGAALFTLARMYERRIFIPAESDALRLEEHEQFNRKIVASAPVGICILRTADGVNILSNELAHTYLNMLTHEDRQRLTQIICGQQVNFVDVLTSNNTNLQISFVHSRYRNENVAICVLVDVSSRVKMEESLQEMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPKGVDRLVTAMNNSSSLLLKIISDILDFSKIESEQLKIEPREFSPREVMNHITANYLPLVVRKQLGLYCFIEPDVPVALNGDPMRLQQVISNLLSNAIKFTDTGCIVLHVRADGDYLSIRVRDTGVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLISMMDGDISVDSEPGMGSQFTVRIPLYGAQYPQKKGVEGLSGKRCWLAVRNASLCQFLETSLQRSGIVVTTYEGQEPTPEDVLITDEVVSKKWQGRAVVTFCRRHIGIPLEKAPGEWVHSVAAPHELPALLARIYLIEMESDDPANALPSTDKAVSDNDDMMILVVDDHPINRRLLADQLGSLGYQCKTANDGVDALNVLSKNHIDIVLSDVNMPNMDGYRLTQRIRQLGLTLPVIGVTANALAEEKQRCLESGMDSCLSKPVTLDVIKQTLTLYAERVRKSRDS
Protein: Cytochrome c oxidase subunit 3 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide III) (P00420)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of COX2 and heme A of COX1 to the active site in COX1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix (Probable). COX3 is a catalytic core subunit.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:30598554}; Multi-pass membrane protein {ECO:0000269|PubMed:30598554}.
Interaction partners:
- Cytochrome c1, heme protein, mitochondrial
- Cytochrome c oxidase subunit 8, mitochondrial
- Cytochrome b-c1 complex subunit 1, mitochondrial
- Cytochrome c oxidase subunit 13, mitochondrial
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Cytochrome c oxidase subunit 7, mitochondrial
- Cytochrome c oxidase subunit 2
- Cytochrome b
- Cytochrome b-c1 complex subunit 8, mitochondrial
- Cytochrome b-c1 complex subunit 2, mitochondrial
Sequence:
MTHLERSRHQQHPFHMVMPSPWPIVVSFALLSLALSTALTMHGYIGNMNMVYLALFVLLTSSILWFRDIVAEATYLGDHTMAVRKGINLGFLMFVLSEVLIFAGLFWAYFHSAMSPDVTLGACWPPVGIEAVQPTELPLLNTIILLSSGATVTYSHHALIAGNRNKALSGLLITFWLIVIFVTCQYIEYTNAAFTISDGVYGSVFYAGTGLHFLHMVMLAAMLGVNYWRMRNYHLTAGHHVGYETTIIYTHVLDVIWLFLYVVFYWWGV
Protein: Protein LONG AFTER FAR-RED 3 (EC 3.5.-.-) (A0A1I9LN01)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for phyA-controlled responses to continuous far-red light (FRc) conditions, including the inhibition of hypocotyl elongation and the regulation of XTH15/XTR7 expression.
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:14645728}.
Interaction partners:
- IAA-amino acid hydrolase ILR1-like 4
- IAA-amino acid hydrolase ILR1
- IAA-amino acid hydrolase ILR1-like 6
- IAA-amino acid hydrolase ILR1-like 2
- IAA-amino acid hydrolase ILR1-like 1
- IAA-amino acid hydrolase ILR1-like 3
- IAA-amino acid hydrolase ILR1-like 5
Sequence:
MTGWYEFPVMIGFVSAAVFLLISVAYLPLLNDLYWSTLKSLTPPAGIVADLLVTNGTIFTSDSSLPFADSMAIRNGRILKVGSFATLKGFIGDGTMEVNLEGKIVVPGLIDSHVHLISGGLQMAQVGLRGVSQKDEFCKMVKDAVQNAKEGSWILGGGWNNDFWGGELPSASWIDEISPRNPVWLIRMDGHMALANSLALKIAGVISLTEDPVGGTIMRMPSGEPTGLLIDAAMELVTPWVKEISVDERREALFRASKYALTRGVTTVIDLGRYFPGTTDELSWKDFQDVYLYADSSKKMMIRTCLFFPITTWSRLLDLKLQKGSVLSEWLYLGGVKAFIDGSLGSNSALFYEEYIDTPNNYGLEVMDPEKLSNFTMAADKSGLQVAIHAIGDKANDMILDMYESVAAANGDRDRRFRIEHAQHLAPGSANRFGQLHIVASVQPDHLLDDADSVAKKLGSERAVKESYLFQSLLNGNALLALGSDWPVADINPLHSIRTAVKRIPPKWDHAWIPSERISFTDALIAQTISAARAAFLDHHLGSLSPGKLADFVILSTNSWDEFSKDVSASVLATYVGGKQLYP
Protein: Threonine dehydratase (EC 4.3.1.19) (Threonine deaminase) (Q9AXU4)
Organism: Nicotiana attenuata (Coyote tobacco)
Function: Catalyzes the conversion of threonine to alpha-keto butyrate in isoleucine (Ile) biosynthesis. Required for JA-Ile biosynthesis, a signaling molecule involved in defense and resistance to the herbivore Manduca sexta caterpillars.
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
- Acetolactate synthase small subunit 1
- Acetolactate synthase small subunit 1
- Acetolactate synthase
- Acetolactate synthase
- Putative low-specificity l-threonine aldolase 1
- low-specificity L-threonine aldolase
- phosphoserine phosphatase
- Tryptophan synthase
- Tryptophan synthase
- tryptophan synthase
Sequence:
MEVLCQAPAGNSNFACNPKFTAIRTRAISSNDTFKVISSTGNNKKMKGAIRTSIPKPSALPLKVSQLSPSADSMPVPASLQDVEAGKLIENNPSGGDTEELFQYLVEILASRVYDVAIDSPLQNAAKLSKKLGVNFWIKREDMQSVFSFKLRGAYNMMTKLSKEQLERGVITASAGNHAQGVALGAQRLKCTATIVMPVTTPEIKIEAVKNLDGKVVLHGDTFDKAQEHALKLAEDEGLTFIPPFDHPDVIIGQGTIGTEINRQLKDIHAVFVPVGGGGLIAGVAAYFKRVAPHTKIIGVEPFGASSMTQSLYHGERVKLEQVDNFADGVAVALVGEETFRLCKDLIDGMVLVSNDAISAAVKDVYDEGRNILETSGALAIAGAEAYCKYYNIKGENVVAIASGANMDFSKLKLVVDLADIGGQREALLATFMPEEPGSFKKFCELVGPMNITEFKYRYNSGRKQALVLYSVGVNTKSDLESMLERMKSSQLNTVNLTNNNLVKEHLRHLMGGRSEPSNEIFCQFIFPEKPGALRKFLDAFSPRWNISLFHYREQGELDASVLVGFQVPKGEIEEFRVQANNLGYSYEIESLNEASQLIME
Protein: Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5) (Q9Y345)
Organism: Homo sapiens (Human)
Function: Sodium- and chloride-dependent glycine transporter. Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses.
Subcellular location: Cell membrane {ECO:0000269|PubMed:16751771, ECO:0000269|PubMed:31370103}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Glycine receptor subunit alpha-1
- Glycine receptor subunit beta
- Neutral amino acid transporter B
- Rho guanine nucleotide exchange factor 9
- Gephyrin
- Dihydropyrimidinase-related protein 5
- Syntenin-1
- Vesicular inhibitory amino acid transporter
- Glutamate decarboxylase 1
- Vesicular glutamate transporter 2
Sequence:
MDCSAPKEMNKLPANSPEAAAAQGHPDGPCAPRTSPEQELPAAAAPPPPRVPRSASTGAQTFQSADARACEAERPGVGSCKLSSPRAQAASAALRDLREAQGAQASPPPGSSGPGNALHCKIPFLRGPEGDANVSVGKGTLERNNTPVVGWVNMSQSTVVLATDGITSVLPGSVATVATQEDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVISDHPKIQIKNSTFCMTAYPNVTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLALCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMHLAPGRFIERLKLVCSPQPDWGPFLAQHRGERYKNMIDPLGTSSLGLKLPVKDLELGTQC
Protein: Glycosyltransferase family-like protein, putative (Q386C4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MWGFCKIDKQQREAHYANNYRRPRELDFSVVCGCWCPEKLLTCTFSSIYFNVKDTRPLLVVYINKGKVGVPFLVAQHLSSQQMFCRSVKWFSVFDACYVLNLDRRQDRWAHVQQQLSRAKLETFLRPPAKVTRVSGVDGQALDVEALHRNGLVTDVGYQRFLLPLEEKLFGMDLTPGAIGCALGHRKIWETVVEKRHQCALILEDDVEFHHKFPRLLREVWPRVPSDWGIVHLGGLDLLASGKPPRPFVDVGVRHAYSGHRELTAYVLHHVAAKRCLEHTLPMTWQVDTHICSVVTEDPAAQDSYISDPMTYVFQPSLAIQITSFGTDVQKRPSDNPPLEDAARRMREFVGGGTSVR
Protein: Predicted gene 4924 (A0A1B0GR71)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MDLVTYEDVHVNFTQEEWALLDPSQKSLYKDVMLETYRNLTAIGYKWEDFNIEEHCKCPKRHERYIICHSGFKPCEDKQYKKKQCTLVSPRTIRQCVVVPTMRRHDDCDTDLQLTGFLTSMAAHHQTNTGEKPYEYKEYRNSSVYTGSLCTCHVAHKIGKYYAYNQCDKTLSSSSSLLGCEKILVGKGSDKSEPCTKGFNHHRYLQTHKRTNSEDLYEYNQHDKDFRSNSSVKLHERTHLEIELYEDNQSEKAFATHSLHQVPRSHTREERYGYDQCGNTFACLSYLQIHERISLEKPFECNQCSKAFAYKRHLHRHEKIHTGEKPYGCNQCGKAFVYNSYLQRHKRSHTGEKPYECHQCGKAFSRNSHLYRHERSHTGEKPYGCNKCGKAFGRNSTLQRHERSHNGEKPYGCNKCGKAFGRNSTLQRHERSHNGEKPYERKQCDKAFAQNSHLFHHEVNCTQEKSYGCSQCGKAFAYNSLLQRHERSHTGEKPYECNKCGKAFSQNSHLHKHERSHTGEKPYGRKQCDKAFAQNSHLFHHEINCTQEKSYGCSQCGKAFAYNSHLQRHERSHTGEKPYECNKCGKAFSQNSHLHKHERSHTGEKPYGRKQCDKAFAQNSHLFHHEINCTQEKSYGCSQCGKAFAYNSQLQRHERSHTGEKPYECNKCGKAFGHYSNLQRHERNHTGEKPYECKKCGKAFSQNSHLHKHERSHTEEKPYGRKQCDKDFAQKNLLHSHERNLSGQKPCEYNQSGKAFAQNSHLFHHEIDHTQEKSYGCSQCGKAFAYNSQLQRHERSHTGEKPYGCNKCGKAFAQKNNLHSHERSHTGEKPYECKKCGKAFSQNSHLHKHERSHTGEKPYGRKQCDKAFAQNSHLFHHEINCTQEKSYGCSQCGKAFGRYSNLQRHERSHTGEKPYECNKCGKAFSQNSHLHKHERSHTGEKPYECNQCLKAFACKSNLYRHERRHT
Protein: Ubiquitin-conjugating enzyme E2 E2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E2) (UbcH8) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2) (Q96LR5)
Organism: Homo sapiens (Human)
Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Catalyzes the ISGylation of influenza A virus NS1 protein.
Interaction partners:
- E3 ubiquitin-protein ligase parkin
- E3 ubiquitin-protein ligase RLIM
- Ubiquitin-like modifier-activating enzyme 1
- Ubiquitin-like modifier-activating enzyme 7
- Ubiquitin-conjugating enzyme E2 E1
- Ubiquitin-conjugating enzyme E2 E3
- E3 ubiquitin-protein ligase RNF8
- E3 ubiquitin-protein ligase SIAH1
- E3 ubiquitin-protein ligase ARIH1
- Ubiquitin-ribosomal protein eL40 fusion protein
Sequence:
MSTEAQRVDDSPSTSGGSSDGDQRESVQQEPEREQVQPKKKEGKISSKTAAKLSTSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSPDYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNRAEHDRMARQWTKRYAT
Protein: Gonadotropin II beta subunit (Q9W6Q7)
Organism: Salmo salar (Atlantic salmon)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU004069}.
Interaction partners:
Sequence:
CPTCLVIQTPICSGHCVTKEPVFKSPFSTVYQHVCTYRDVRYETIRLPDCPPWVDHHVTYPVALSCDCSLCNMDTSDCTIESLQPEFC
Protein: TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (TAB1-like protein 1) (TAK1 kinase/MOM-4 binding Protein) (G5EEM6)
Organism: Caenorhabditis elegans
Function: Involved in the Wnt signaling pathway by regulating mom-4 kinase activity.
Interaction partners:
- Mitogen-activated protein kinase kinase kinase mom-4
- Mitogen-activated protein kinase kinase kinase
- Protein pellino
- Ubiquitin-conjugating enzyme E2 13
- RING-type domain-containing protein
- Mitogen-activated protein kinase pmk-1
- Mitogen-activated protein kinase kinase kinase zak-1
- Pelle-like serine/threonine-protein kinase pik-1
- Glycogen synthase kinase-3
- Protein kinase domain-containing protein
Sequence:
MGDDGFLDQYPANTDAGIGTVHSCRYSKQKNPVQNNDFLSCSMCIHNGPIKLYGIFSGFNGGDSTAKFVMNRLVYEIFGENPITPTLLPYQVVEEFKRKFENVAERYLLMNTDDLNNRLLKLEEQSETGNNAVSEINQKIRQGTTAIVVMIINQDLYVLNCGNSLAIAMNSENVVQLNSNLHNNDNPLEIVRIKGLGINPETVLNPTRAIGDLQRTHLFEETEAFKNAKGPPVISTPDVQYTKIDPSWRHLVLISDGVVQNLKEVEVENIPTEVSVRLIEDHTVTSTAQALVDSFARKHRDAYTMSDDKNFCISNHREEMTVIYVKLEEDYQAALYEQFDSAISTMESTNATLYEPCSTPYVDATNFNSGKNYEKMKKLLLTRPSK