wanglab/gogpt-training-data huggingface dataset:
Protein: Inorganic pyrophosphatase TTM1 (EC 3.6.1.1) (Triphosphate tunnel metalloenzyme 1) (AtTTM1) (Q9C9B9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Exhibits pyrophosphatase activity with stronger affinity for pyrophosphate (PPi), moderate affinity for ATP and ADP, and weak affinity for tripolyphosphate (PPPi). No activity observed toward uridine substrate. Regulates positively natural and dark-induced leaf senescence.
Subcellular location: Mitochondrion outer membrane {ECO:0000269|PubMed:28733390}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Uridine nucleosidase 1
- Uridine 5'-monophosphate synthase
- Uracil phosphoribosyltransferase, chloroplastic
- UMP kinase
- dCMP deaminase
- Alkaline-phosphatase-like family protein
- Dihydroorotate dehydrogenase
- Cytidine deaminase 5
- Cytidine deaminase 6
- Cytidine deaminase 7
Sequence:
MALDSSVALSPRRRHGLLRDQVQLIKRKDSGRYEIVPIEDPLSFEKGFYAVIRACQLLAQKNDGLILVGLAGPSGAGKTIFTEKILNFMPSIAIINMDNYNDGTRVIDGNFDDPRLTDYDTLLDNIHGLRDGKPVQVPIYDFKSSSRIGYRTLEVPSSRIVILEGIYALSEKLRPLLDLRVSVTGGVHFDLVKRVLRDIQRAGQEPEEIIHQISETVYPMYKAFIEPDLKTAQIKILNKFNPFSGFQNPTYILKSSKAVTPEQMKAALSEDFKERTEETYDIYLLPPGEDPEACQSYLRMRNRDGKYNLMFEEWVTDRPFIISPRITFEVSVRLLGGLMALGYTIATILKRKSHIFDDDKVIVKTDWLEQLNRTYVQVQGKDRTFVKNVADQLGLEGSYVPHTYIEQIQLERLVNDVLALPDDLKTKLSLDDDTVSSPKEALSRASVDSRMKYLHGGVSKSYTNPRHKVLPNLTRLAVNNRMLDARAPASPATLPNQGFITQLSDQISTLNERMDEFTSRIEELNSKIPNRIAPSGSQHNLALPIENGNGSVLSFSASASQLVRESPLMEEVVLVARGQRQIMHQMDTLSNLLREYVGEKTRIERLDSSRTNSTTQNLESSTVPILLGLAIGCVGIFAYSRLK
Protein: Probable serine/threonine-protein kinase drkC (EC 2.7.11.1) (Receptor-like kinase 3) (Receptor-like kinase C) (Vesicle-associated receptor tyrosine kinase-like protein 3) (Q54TA1)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MIIINKYIRMNKIAILFSFFILICCTGYSISYKINGINENKVLSLSSSPSPSSSSSSSQILEKGKEEIKKIKKTNKNKLLYNVAIVDLEPKLEIEQELLTRNNKKKMEMKEEMDIAMMMMKAADRTDQVSTSSSSSSFSEENKKSSSDDSAPAIQSNLTFSGYMTGGEQVCDPKSCNSPSVFTQNYLCNTSSAWANGYVFHDPVPPTGLFVVHKIVVTFTGMFNVIPPTSMVFSLVNGEENAGIFFISKSSPSQCPNCQISFSPRTLPDVDPNGLASYRYGSNNSIIFNLFETDVACIGKVTANIFYGPVAFKVNSVVPNTAPSTGGETVYFIGEQFYQSSQIQCKFGTVISTGTYINSTCASCVVPPMLQSNSTTPSDYNVTIQLSEDGGSSFCLNTTFFIYTAASIPFVKPTSPNYQKIIYIVVGVGIAVLLIIAVGIYFIIRLRIKNKRLNGSKHALPIGINDDERSPLLKTDYKTLFEIKPIDISEIVVQNRIGRGSCAEVFTGTWRGIIVAIKKAKLLNEDDEDFLNELAQEATIMSQLRHPNICQFLGTCNNPPEILIVMEYMPLGSLYRILHDPSISLDWPRMKSMALDIAKGMNYLHCCDPIVIHRDLKSHNLLVDEHYRVKISDFGLSTRFKKHLDKKTAMTPVGTPCWTAPEVLRNDPYTEKADVFSFAIVLWEIVTREDPYQGMPTFQIVISVGQHKLRPIVPPQVSAPFTRLITECWSEDPQQRPSFQEIVKRLEAM
Protein: Schlafen family member 1 (Schlafen-1) (Q9Z0I7)
Organism: Mus musculus (Mouse)
Function: Protein expressed in resting T-cells, which is required for maintaining T-cells in the quiescent state. Acts by promoting cell-cycle arrest of T-cells through inhibiting the expression of cyclin-D1 (CCND1).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18373498}. Nucleus {ECO:0000269|PubMed:18373498}. Note=Translocates into the nucleus following interaction with DNAJB6. {ECO:0000269|PubMed:18373498}.
Interaction partners:
- DnaJ homolog subfamily B member 6
Sequence:
MNITDEGTPVLILNAGGITLGTESRKTMENHDRVEENRNITKALCALINSGEGKVKAHIKNPDYILSKHGIGEDLETSFKNILPSRPLDFKQYQSYFFICVEKSQSPDVSVGKPATIATNLYMRNGASSVEMNLDAAQKFLDNIKVAGGRSPSARPSDRPGDDTQEEGHIQELAAAFFKQSKLTKKENFLFSESKNVEYKSFETKKLLQRVKEILPRTVSAFANTDGGYLFIGLDEKKQEIVGFEAKNCQPKCLESEIEKCIQQLPVTHFCEEREKIKYKCKFIEVHDSGVVCKYVCALRVERFCCAVFAAEPESWHMKDGGVKRFTIEEWIKLLMS
Protein: FI03335p (Glutamate receptor interacting protein, isoform A) (Q9W450)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Frizzled-2
- Kon-tiki, isoform B
Sequence:
MKLWKSKKPIGGCVPGKSAALKQDQQQQQQQQQESHNNSFNGHHHPPTDTALAPMLSVDRAMSPAQSEDSGLAPERGTTYATITLPRNALHLAITFAERNDLSYPPVVGSLNPVGHAADFLAPGDRLHQIDGISTIGLSNQKVMNMLCAGGSDACPAIVEIEYSLPECTVSQNSLCVTSKLAQITVERESGCLGLTLRGGADYPLIVTHVRPHGPVYKTGRIKPGDRLLRVDNVSLIGKTLAEAQQIIKCGGHVSGYTNLTIEYDVSVVQSVEFSMGPLLIEIERPMNDKLGLVLCNYTAAVPASGSGSSTPSSGEKIEESAGVFIASILPASIADRCGALSVGDQVLSIDDTMIEHTAFSPDEVMTILDTSTGRGYTQMQIMPAHALARRGHTTLGSPKYSFSTLESRKSSTAGRQRQRFARKSSLPLENPACGTPGSTGGSMGTGGIHGSSSLGMGLGLCRAESFPVLLDCSHGAGIILSETVSGSGGSGAVAIAQIVPDSVADRSGCIQAGDRIVAINKMYSLDAAAMRQLLEGGSSRNGASNGTPANWLELEIEFDMPDAVVPASGVFSVKLLRAGKCGLGLSVSGSSHGGLVISDVKMGSPAHRSGSLRSGDILLAVDQHPVQHFNVDALLKEEGRSQNPSHSSSDFTTLTIKRIVLPDFLPMSSPIYSNCPASGINLGMGMGVSTSTDHDLYSSAYVTAGKYADCVSLKSRTPQPDYFRVPSMDDASLQSVQLRSGSGSNGGNQAANSWSTGVNSRSYVAPPNTQSLTTELPEEEDEQEQMYPGYELNRYASVDCTALPPPMENKVYGSAASSSSKSSGSSLHQIIFTVRLEPKGGLLGITLAGSEDITKSITISGLVEGGIAHKNGQIHVGDQLLAIDEHSVQGMPLSHATSLLQNLGDLVDLKILRSHDLANGSHLPQTQAIYAKVQRRPRSPSANTEASKESGSGNANGGGAVNGNSGSGKPRVFHVTLYKDKVYDDYGFSVSDGLYERGVFINRIRSGGPADMCGLLKPFDRIMQVNEMKTQDFDCCLTVPLIAAAGDKIEMIMQRSE
Protein: Interleukin 4/13A (E7FKY3)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
Sequence:
MKTAILLLSVAMVLFDSGTLPANAAAHRQHRSHNSNLEAIISMAGQYTHTLSEELLETLLIDVTHLTATTTKCKEFFCEAETILASVKNDAFGEEGKIVRHLRVYNKLQKCTVVKSQDQVEGNQV
Protein: Cation channel sperm-associated auxiliary subunit epsilon (CatSper-epsilon) (CatSperepsilon) (C1orf101-like protein) (P0DP43)
Organism: Mus musculus (Mouse)
Function: Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization.
Subcellular location: Cell projection, cilium, flagellum membrane {ECO:0000269|PubMed:28226241}; Single-pass type I membrane protein {ECO:0000255}. Note=Specifically located in the principal piece of sperm tail. {ECO:0000269|PubMed:28226241}.
Interaction partners:
- Cation channel sperm-associated auxiliary subunit gamma 2
- Cation channel sperm-associated protein 2
- Cation channel sperm-associated auxiliary subunit beta
- Cation channel sperm-associated auxiliary subunit delta
- Cation channel sperm-associated auxiliary subunit zeta
- EF-hand calcium-binding domain-containing protein 9
- Cation channel sperm-associated protein 1
- Cation channel sperm-associated protein 4
- Cation channel sperm-associated protein 3
- Solute carrier organic anion transporter family member 6C1
Sequence:
MPSAGQRKPGSLLALQALQKWLLRGGVGAMLARQVVAALLLWLSCCVSALWRYYINSQDYSIFSTRSSIKLEYEGNSFVSWKIPESCKVENTTSPKTTLHCKRAGIHTIKPIAGNQEVERHLTVDNSYICYLWYFTVVDVYYNLSQIVTIWVYDPESASTEELIWTAKKPSLSSRVLTKQMNTLGQRPFIFTVEKRLTYHPGPLTSEGTWVIHLPMSSDDIAKVIRGNKVAFQDCFIANLYFMLTYPMTIISEPPGYEPLTVPPGSPLMLSWDTCISTFALLATDQETFQTNDSFQTWTRVRAPPGILSDAQRHSLRDVIIFDQGTLFLVDGTVYLRTEDEFTKLDESRGISETGILGFSKRRWCQIRYLYKLASKKSILIAWSKTTVYAGYATFRFVTLTDTAKLKDFLKLPQTDTLEVMSVEYLWHPLEAAVLLSHCSVCTTNTRNIRIVIYSAIFQTWTLQDFELQLPKEAILEFRFLYSAMPDIIMWDQHHVYYSYKNFTVVGTISTPSGETNLSSLSQGSKIHQVLTDRIGNVVVKMENNVMFYIKADITEAVILHTWVNTTAKTVVLFDKSFEVCILYYNENLDEKYQLQTQPYPLILELQSINKDLGDWCPYLAFQHNIHSQFYHMDKGESLTIWSQIVYPENRGLYIVVEHYGSSVMTWTQNLEYEIASGFCTKTMITRFFQTTNYELVDNYYQLQKENTGLMLLQFRPSEFSRTCLTAKPVFEIDVGCDSSKYIMVRGFNKSRCQRRDFSYVIDKELLRESLSDNLKVRYDVAKYGCPLTLELGQMFQPIVELYDENGFIKIVDANFILWEIHGRNDYTFNSTMEQNGCINEAQTWDSMIEENPDIPLDDVWGPQNYRPCFSYAIGKPGDLGQPYEILNYSNKNHIKWPMTYAGMYVYRLKILDPNYSFCNLTTIFAIESLGMIPRSSVYLVAALIFVLMLTFISILVLSYFWYLKIYRQFIIEPLHKRPAKQKKN
Protein: GMP reductase 1 (GMPR 1) (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 1) (Guanosine monophosphate reductase 1) (Q9Z244)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
Interaction partners:
- GMP synthase
- Bifunctional purine biosynthesis protein ATIC
- Adenylosuccinate synthetase isozyme 1
- Adenylosuccinate synthetase isozyme 2
- 5'-nucleotidase
- AMP deaminase 1
- AMP deaminase 3
- AMP deaminase 2
- Adenine phosphoribosyltransferase
- 5',3'-nucleotidase, mitochondrial
Sequence:
MPRIDADLKLDFKDVLLRPKRSSLKSRSEVDLERTFTFRNSKQTYSGIPVIVANMDTVGTFEMAVVMSQHAMFTAIHKHYSLDDWKHFAENHPECLQHVAVSSGSGQNDLEKMSLILEAVPQVKFICLDVANGYSEHFVEFVKLVRSKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGSCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVIERNGQKLKLFYGMSSDTAMKKHAGGVAEYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVTQQHNTVFG
Protein: Endonuclease or glycosyl hydrolase with C2H2-type zinc finger domain-containing protein (F4K209)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MSTAEADYVKAKTSVWWDIENCEVPRGWDAHVIALNVSSSLLKMNYCGPVSISAYGDTNLIPLHHQQALSSTGVALNHIPAGVKDASDKKILVDMLLWAIDNPAPANLLLISGDRDFSNALHQLRMRRYNILLAQPPRASVPLVAAARDVWLWTVLASGGPPLTSVESSLLFNNGGFRVSNKGVSKLPVSEQAQPSQPTGSTSNAGDTKDHKTREKHVPRGSLQENRKNMLQHSSGATGESATTCRICNVVCDSFEKFTAHLSDIRHISQAAIVESRRAQASVSAKPIHQAVLVEPLLCKVCQISFTNNDTYKNHTYGKKHRNNLELQSGKSKNILVGPAEPSKEVLEKHNMNKKVMIESRAQANAEFVCLMCNVVCQSQIVFNSHLRGKKHANMLSQSEALIVSTKLQEKGVGEKEQPSETVAELQLQSQKAQEKQVLVDSKKLPEKGDEVKGQPKEMTALRNASAKYICRMCNVGCHSPIVFETHLRGQKHAANLNQSKDQALIDSKKLQEKGFGEKEQPRETIVEPQLQSQNAQENSKCFEKHVVMVNQSEVLINASKLEEKDAQEKAQPIESIAEPQSQSQNTQEHTKFFEKQNEELRKICGTLESSVKEPLPSTKDWVETLNKQIPNGEFFFGDLRSDFEVPREASECFDGIVKPVNLSKGETKHSWEAAFVASNGSQSSVSTNPLKEPEGLQPVWCQVCQISCNSKVAFASHTYGKKHRQNLESQSAKNETMSTGPGKLSKDYGEKTKKVSCKNQTTFDSQLKSQNHYTMAKELVEKAFVSAFEHVSALEQFSIVDSRTIREDTDQEKEATKEQTLVKMDGNGFRGAPEDKVELNQEKHREALEQFSIDSRIIREETDQEKEATEEQTLVKMDDLGFRGAPEDKVELKERHTVSENLVHRVFTEQNRESRIPNEPRGCLDVIPERVKLPPNVNVAKNLEDEQKHKPEPKAQEAENKSGGRKDLPGEAAKREEIKGQADNFWTRLWGKKY
Protein: Selenoprotein N (SePN) (SelN) (Q3Y4E2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Plays an important role in cell protection against oxidative stress and in the regulation of redox-related calcium homeostasis. Regulates the calcium level of the ER by protecting the calcium pump ATP2A2 against the oxidoreductase ERO1A-mediated oxidative damage (By similarity). Acts as a modulator of ryanodine receptor (RyR) activity: protects RyR from oxidation due to increased oxidative stress, or directly controls the RyR redox state, regulating the RyR-mediated calcium mobilization required for normal muscle development and differentiation. Plays an important role in muscle development and differentiation during early development. Required for development of the slow muscle fiber lineage. Required for the correct organization and attachment of the myofibrils, as well as for the continuity and integrity of the connective tissue that forms the myoseptum.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9NZV5}.
Interaction partners:
- Selenoprotein K
- Selenoprotein S
- Selenoprotein M
- Selenoprotein F
- Protein adenylyltransferase SelO-1, mitochondrial
- Ryanodine receptor 1a
- Selenoprotein J.
- SECIS-binding protein 2.
- Uncharacterized protein.
- Selenide, water dikinase 3
Sequence:
MAADVDKTPAGEQKDDHEDRGTPSSRRGRSRFTQISSLFIIAAIPVIGVCIKYYLDIQFVKRHEAGLKALGADGLFFFSSLDTDHDLYLSPEEFKPIAEKLTGVAPPPEYEEEIPHDPNGETLTLHAKMQPLLLESMTKSKDGFLGVSHSSLSGLRSWKRPAISSSTFYASQFKVFLPPSGKSAVGDTWWIIPSELNIFTGYLPNNRFHPPTPRGKEVLIHSLLSMFHPRPFVKSRFAPQGAVACIRATSDFYYDIVFRIHAEFQLNDVPDFPFWFTPGQFAGHIILSKDASHVRDFHIYVPNDKTLNVDMEWLYGASETSNMEVDIGYLPQMELGAEGPSTPSVIYDEQGNMIDSRGEGGEPIQFVFEEIVWSEELRREEASRRLEVTMYPFKKVPYLPFSEAFSRASAEKKLVHSILLWGALDDQSCUGSGRTLRETVLESSPVLALLNQSFISSWSLVKELEDLQGDVKNVELSEKARLHLEKYTFPVQMMVVLPNGTVVHHINANNFLDQTSMKPEDEGPGLSFSAGFEDPSTSTYIRFLQEGLEKAKPYLES
Protein: Chronophage, isoform L (A8JV11)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MYNKMLSISEDHGFRSLSHSDSTENDAVATQDILTCGACQKAFALSDIVKFIQHKVLQCNKENYGQCATQNPQMDRDAEEGRPLSLVNRRPSISAPISGRKSAPASAAAAVAAAAAAAAAAAAASSTASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKDSETGATTLDSNAAPSSPAAIERQSSGDSSCEMEEQQDRQDKQSQPKQAKVKQEPYDEEGVNHHQNQDDDDDEEMEERSLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVESPGGGATLTVATPAALNNSALALAAAAAAASASGLASPQPAVSPNPAVTSSAKRSSPLGAAGSTILSTSVSSTCSNSLVNTSGGSISNTSSIGSPQQQQLQLQQQQAQQQQQRVQQQQRENLASAMAAGMRHHPLLPPPEAMHANPFQLLRMPLPPALAQAGNVVPTVAPLFGRPSPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNANGQVVGGVVSGSGEPRPPSSSSSGSQRGSVPPAALPPPSLSSQQQQQQQQAVQQQQQQGAQQQLQSAQQQQQSQQQSQQQQQITPGLVGGAGGSLKLEPQQMDFYSQRLRQLAGTTSPGAGSTVNSSSPSPRQKQSPHFASPSPSQQQQQQLATIPRPHSLTPPEKLGDASSENGSLGLILASTPRSASTPPSKTGDVSLQEPIAHCYSCSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPADDQDNQDNQDDGSNADSLETNEADNDEDPNPDESEEELGDGDNDPDGDGDLDGEDEDEDELEECEDMDYKAEDLSVSNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAAAAAAAAAADNNNRGGAGAPLSDKLNGLPVAALRLRDEFAKNCNMFQQPQDGGAPSQVPLFNPFPNPFELSKRMKMDGGDWWGMSQALHRNEALFENLKLKPLGLGGANSLIQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAANAVAAAQAAQAAAQHIQAAAQQAQAVQAQAVQAQAAQQSQQQQQQLSPMGVVGYPPQFVSGHNLSLPGSVSGDNDSNASSSMTGVHPISLKEEA
Protein: Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (F1LVW7)
Organism: Rattus norvegicus (Rat)
Function: Actin nucleation and elongation factor required for the assembly of F-actin structures, such as actin cables and stress fibers. Required for cytokinesis, stress fiber formation and transcriptional activation of the serum response factor. Binds to GTP-bound form of Rho and to profilin: acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics. Also acts as an actin nucleation and elongation factor in the nucleus by promoting nuclear actin polymerization inside the nucleus to drive serum-dependent SRF-MRTFA activity.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18651670}. Nucleus {ECO:0000269|PubMed:18651670}. Note=During mitosis, co-localizes with the actin-rich cleavage furrow and with the microtubule-rich central spindle during cytokinesis (By similarity). Shuttles between the cytoplasm and the nucleus (By similarity). {ECO:0000250|UniProtKB:Q9NSV4, ECO:0000250|UniProtKB:Q9Z207}.
Interaction partners:
- Cell division control protein 42 homolog
- BAR/IMD domain-containing adapter protein 2
- Protein diaphanous homolog 1
- Rho-related GTP-binding protein RhoB
- Transforming protein RhoA
- Ras homolog family member F, filopodia associated
- Ras homolog family member C.
- Profilin-4
- Rho-related GTP-binding protein RhoG
- Profilin-2
Sequence:
MEKHRARALGRDSKASRRKGLPSAPPAGPYELGEKRPKLHLNIRTLTDDMLDKFASIRIPKGSKKERPPLPQLKTVSGSSDYSSVSSETMENNPKSLSENEVLKLFEKMMEDMNLNEDKKAPLREKDFSIKKEMVMQYINTASKTGSLRSSRQISPQEFIHELKMGYTGERLFTYLESLRVSLTSNPVSWVQNFGHEGLGLLLDILEKLINGQIQEKVVKKTQHKVIQCLRALMNTQYGLERIMSDERSLSLLAKAMDPKQPSMMADVVKLLSAVCIVGEESILEEVLEALTSAGEERKIDRFFSIVEGLRHNSVQLQVACMQLINALVTSPDDLDFRLHLRNEFMRCGLKEILPNLKGIKNDGLDIQLKVFDEHKEEDLSEFSHRFEDIRAEFDEASDVYSVVWDTVKETRAEGHFVSILQHLLLIRNDRFIRQQYFKLIDECVSQIVLHRDGIDPDFTYRKRLDLDLSQFVDVCIDQAKLEEWEEKASEHCKKFEKECTDHQETQAQLQKKEAKINELQAELQAFKSQFGALPPGTKIPLQTSAKGEPGPSAFPPAPPALGAGVPPPPPPPPPPPPPLPGMAMPFGGPVPPPPPLGFLGGQNFIPLNLPFGLKPKKEFKPEISMRRLNWLKIGPNEMSENCFWIKVNENKYENKDLLCKLENTFCCLEKEKRDTNDFDEKKVIKKRMKELKFLDPKIAQNLSIFLSSFRVPYEKIRTMILEVDEAQLSESMIQNLMKHLPDEEQLKSLSQFRSDYNSLCEPEQFAVVMSNVKRLRPRLTAILFKLQFEEQVNNINPDIMAVSTACEEIKKSKSFSKLLELVLLMGNYMNAGSRNAQTFGFDLSSLCKLKDTKSADQKTTLLHFLVDVCEEKHPDILPFVDDLAHLDKASRVSVEMLEKSLKQMGRQLLQLEKNLETFPPPEDLHDKFVIKMSSFIITAKEHYGKLSTLLDNMTQLYQSVMSYYAVDTKKVSVEEFFNDLNNFRTSFMQALKENIRKREAAEKEKRARIAKERAEKERLERQQEKKRLLEMKTEGDETGVMDSLLEALQSGAAFRDRRKRTPKLKDIRQSLSPMSQRPVLKVCNHENQKMQLSEGSRPHHSINCTSTRTPVAKELNCNLDTHTSTGRIKAVEKEACNAESNRKKEMELLGSVSKSESVPEVEALLARLRAL
Protein: Large ribosomal subunit protein uL29x (60S ribosomal protein L35-3) (Q9M3D2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Large ribosomal subunit protein eL32y
- Large ribosomal subunit protein uL13x
- At5g09770
- Large ribosomal subunit protein uL14x/uL14z/uL14y
- At5g64650
- At1g01640
- Large ribosomal subunit protein uL13z
- Large ribosomal subunit protein uL13w
- Large ribosomal subunit protein uL13y
- Small ribosomal subunit protein uS9x
Sequence:
MARIKVHELRDKSKSDLSTQLKELKAELASLRVAKVTGGAPNKLSKIKVVRKSIAQVLTVSSQKQKSALREAYKNKKLLPLDLRPKKTRAIRRRLTKHQASLKTEREKKKDMYFPIRKYAIKV
Protein: Dentin sialophosphoprotein-like protein (Q9M1S4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Serine/threonine-protein kinase ATR
- Nibrin homolog
- DNA repair protein RAD50
- Probable inactive protein kinase At3g63330
- Double-strand break repair protein MRE11
- Chlorophyll a-b binding protein 3, chloroplastic
- E3 ubiquitin-protein ligase PRT1
- Protein NBR1 homolog
- ATP-dependent DNA helicase 2 subunit KU70
- Cell cycle checkpoint protein RAD17
Sequence:
MEEPREESEAVRDCSEPMEEAGKGSGLSSKTETLVDEDANTDLGVSDKNPNDGGLATVDVDDDDDVKRTDAVTEIECEGDTGTVEVKLNDETAKSEVKSKSGATHETAGEEETENSVANEATDEKATCEVEDNGGVCDAEQDVETENFQLNPVHGETLSVAEDKADQEKETTKKIEKDINEMEVDSKQEDEENETEDAKHSESAQVPEESTKLSKEETDEENQKEENGVAMEIDGVAGEHVEKVVKVGSGSDNACNESAGASMVQTQDVPIAEADNNESNVVKKMEIDERKDNADMTSDLTGTIESADSAIPNSPTEDAAPGEVEPLDHNALFDPTSDITNFIDFSGVSSWSGNIQDLKTETGNVSLKEDKKVTDMAEDVVTADIETESNEARVGVGAESPAAATDCSKETSDATLGSEENQQDKDHQCLDKKTADVQDTMIEEDDITHEAPSFDPNQKENAEMEENHNNFVYADDEAGSDVKTNGVKRKADVLSEDSPGEGRKTVSFAKVSFAERPSFKIGACIARAASQMAGSPSVLKGSNFGDETLSVESFVSQLHCAATDPVKENVVSDIATGFFLDFRNSSASQQVTTEKVSKKRGRPSNSNVAGTEAFEFEEMGDTYWTDRVIHNGGEGQTPATEKGNYQVVPVELKPAQVQRTRRPYRRRQSQISIPHSATKKPADIDENAPAEIIMNFFETDTIPPEKSLSKMFRHFGPIQELRTEVDREKNRARVVFRKGADAEVAYNSAGRFNIFGTKVVKYELSRNVTETFKVQPYVVSLAEEDAAVCPSS
Protein: Putative cysteine-rich receptor-like protein kinase 9 (Cysteine-rich RLK9) (O65469)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- T1B9.12 protein
- At1g70740
- CDPK-related kinase 3
- Cysteine-rich receptor-like protein kinase 44
- Endochitinase EP3
- Cysteine-rich receptor-like protein kinase 1
Sequence:
MSSLISFIFLFLFSFLTSFKASAQDPFYLNHYCPNTTTYSRFSTYSTNLRTLLSSFASRNASYSTGFQNVTVGQTPDLVTGLFLCRGDLSPEVCSNCVAFSVDEALTRCPSQREAVFYYEECILRYSDKNILSTAITNEGEFILSNTNTISPNQSQINQFIVLVQSNMNQAAMEAANSSRKFSTIKTELTELQTLYGLVQCTPDLTSQDCLRCLTRSINRMPLSRIGARQFWPSCNSRYELYSFYNETTIGTPSPPPPPSPSRAN
Protein: Lysine-specific demethylase 5C (EC 1.14.11.67) (Histone demethylase JARID1C) (Jumonji/ARID domain-containing protein 1C) (Protein SmcX) (Protein Xe169) ([histone H3]-trimethyl-L-lysine(4) demethylase 5C) (P41230)
Organism: Mus musculus (Mouse)
Function: Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements (By similarity). Represses the CLOCK-BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00355, ECO:0000255|PROSITE-ProRule:PRU00537}.
Interaction partners:
- Histone-lysine N-methyltransferase EHMT2
- Histone deacetylase 1
- Eukaryotic translation initiation factor 2 subunit 3, X-linked
- Lysine-specific demethylase 6A
- ATP synthase F
- ATP synthase F
- ATP synthase F
- ATP synthase F
- ATP synthase peripheral stalk subunit OSCP, mitochondrial
- Histone H3.2
Sequence:
MELGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFTPRIQRLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIPNVERRILDLYSLSKIVVEEGGYETICKDRRWARVAQRLNYPPGKNIGSLLRSHYERIVYPYEMYQSGANLVQCNTRPFDNEEKDKEYKPHSIPLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGAGPKMMGLGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKMESTSPKTFLEGKEELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATREYTLQSFGEMADSFKADYFNMPVHMVPTELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFPVSDSKRHLTPEEEEYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYCVFSHEELICKMAACPEKLDLNLAAAVHKEMFIMVQEERRLRKALLEKGITEAEREAFELLPDDERQCIKCKTTCFLSALACYDCPDGLVCLSHINDLCKCSSSRQYLRYRYTLDELPAMLHKLKVRAESFDTWANKVRVALEVEDGRKRSLEELRALESEARERRFPNSELLQRLKNCLSEAEACVSRALGLVSGQEAGPDRVAGLQMTLAELRDFLGQMNNLPCAMHQIGDVKGILEQVEAYQTEAREALVSQPSSPGLLQSLLERGQQLGVEVPEAQQLQRQVEQARWLDEVKRTLAPSARRGTLAIMRGLLVAGASVAPSPAVDKAQAELQELLTIAERWEEKAHLCLEARQKHPPATLEAIIHEAENIPVHLPNIQSLKEALAKARAWIADVDEIQNGDHYPCLDDLEGLVAVGRDLPVGLEELRQLELQVLTAHSWREKASKTFLKKNSCYTLLEVLCPCADAGSDSTKRSRWMEKELGLYKSDTELLGLSAQDLRDPGSVIVAFKEGEQKEKEGILQLRRTNSAKPSPLALLTTASSTASICVCGQVPAGVGALQCDLCQDWFHGRCVTVPRLLSSQRSSLPSSPLLAWWEWDTKFLCPLCMRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAISWQGRARQVLASEEVTALLGRLAELRQRLQAESKPEESLAYPSDGGEGTGNMPKVQGLLENGDSVTSPEKVATEEGSGKRDLELLSSILPQLSGPVLELPEATRAPLEELMMEGDLLEVTLDENHSIWQLLQAGQPPDLKRVQTLLELEKAERHGSRTRGRALERRRRRKVDRGGEPDDPAREELEPKRVRSSGPEAEEVQEEEELEEETGGEVPPVPFPNSGSPSIQEDQDGLEPVLEAGSDTSAPFSTLTSRLLMSCPQQPSLQQL
Protein: Pregnancy-specific glycoprotein 22 (Q810J1)
Organism: Mus musculus (Mouse)
Function: May have an angiogenic function during early placental development. Binds to cell-surface heparan sulfate proteoglycans (HSPGs), and stimulates secretion of the proangiogenic factors VEGFA and TGFB from uterine dendritic cells and natural killer cells. Also induces endothelial tube formation in vitro.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
Sequence:
MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE
Protein: Uncharacterized protein (A8JBY2)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000256|ARBA:ARBA00004430}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000256|ARBA:ARBA00004120}.
Interaction partners:
- Uncharacterized protein
- Intraflagellar transport protein 56
- Intraflagellar transport protein 57
- IFT81 calponin homology domain-containing protein
- Uncharacterized protein
- Intraflagellar transport protein 80
- Osm-6-like protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
Sequence:
MCDNWQATIDTLQGASPVFDKPKLSQKLLEKPPFRFLHDVVTAVQQATGFAPGLYQGDELDGKAIQEKDAKVAYLKKIIEVVSMVLGEQCPARPNKIVAGLEPENTNIFLQMLGRACQKGNGAKAVQKVLGGGGAEPAPAKEEAPPPEKKPEKKEKKEEKPAEKSRAEASPARKKAAEPEAEKKSSSKSSSRTKEEPPAKAPAKKKEEPAPEKPSKSKAAPAAEEAPPPPPPPAAEPPARSASPGGEDPLNKSGSAAPKFQRPTSARKAPPRVPQPQQPTMLAGTGIRPGTATRRPNEPKPTDSKVTKPVAVFTDNAKDNSDDEVEVVHEQTPVLSGGANMTGEQGVLVKDILAAEKGLKKAGVDATADNADTSDQGSTGIILKRLGGKAAGAGAAAAGPRAHDPSSVRELVQKLCHSSTPLAKSMDYLQEDIENMRKEYKFWLTEKRMYQDELARELRLQGEAANVDAQLADLDGQIKQARDRIIGMKGQILRNDETLGKLLAMATAGR
Protein: DNA 5'-3' helicase (EC 5.6.2.3) (Q9XYZ2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MLELKRSLDAKGHCLLEMPSGTGKTATLLSLIVAYMVEHPETVRKLIYCSRTVPEIEKVIAELQNLMVYYERHCPNPPPFTGLVLSSRKNMCIHPEVSKEREGKAVDGKCYGLTASYIRERHEMDTETPICQYFEGFSLEGKESTLPVGVYSIDDLKEYGRSRNWCPYFLARYAIAHAHIVVYSYHYLLDPKIAQVVSKEMSRESCVVFDEAHNIDNVCIDSMSVKINRRTVERSTNALNHLTKLVQDIREEDTNRLNEEYQRMVQGLKDASVQRDTDMILANPVLPNDVLTEVVPGNIRNADHFLSFLRRFIEYIKTRLRVHHVVQESPAGFLKDISSKICIERKPLRFCAERLSSLLRTLEISDLTEYGALTLITHFATLVSTYTKGFTIIIEPFDDKTPTVSNPILHFSCLDSSIAMAPVFSRFQTVVITSGTLSPMDMYPKILDFDPVVMSSFTMTLARPCLLPMIVSKGNDQVTISSKFETREDTAVIRNYGQLLVEVAKTVPDGIVCFFTSYLYLESVVASWYDQGIVDTLLRYKLLFIETQDNAETSYALMNYVKACDCGRGAVLLAVARGKVSEGVDFDHHYGRAVLMFGIPYVYTQSRILKARLDYLRDQFQIRENDFLTFDAMRHAAQCVGRALRGKTDYGIMIFADKRFSRHDKRSRLPKWIQEHLVDSFCNLSTEEAVQLARRWLRRMAQPFTREDQLGISLLTLAQLENMEQEKLERQAQGKQGVGGEVQEL