wanglab/gogpt-training-data huggingface dataset:
Protein: Probable inorganic carbon transporter subunit DabB (Q2G0W2)
Organism: Staphylococcus aureus (strain NCTC 8325 / PS 47)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|HAMAP-Rule:MF_00862}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|HAMAP-Rule:MF_00862}. Membrane {ECO:0000256|RuleBase:RU000320}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU000320}.
Interaction partners:
- Probable inorganic carbon transporter subunit DabA
- Na+-translocating membrane potential-generating system MpsC domain-containing protein
- Putative antiporter subunit mnhD2
- Na
- Type II NADH:quinone oxidoreductase
- Type II NADH:quinone oxidoreductase
- Putative antiporter subunit mnhC2
- Na
- Na
- Putative antiporter subunit mnhA2
Sequence:
MLSFQLLFSLFVIALIIALISGLLFLAPVMPMRYIKLHLYILVMPVLFAVIGFFGIHGQHVLGPFKIDRLSWLLAGFVMALGFIIQKFSMRYLLGDHHYRHYFPLFTAITSFASLAWMSEDLRLMALCWGITLLCLTLLMNVNRFWKVPRESAKLSSMTFLCGWLAFVGAIVTIYIATGEWRVPQHIVHPTWSLLTNVLLVLAVMIPAAQFPFHRWLIESVTAPTPVSAIMHAGIVNAGGVILTRFAPIFDNGFALSLLLILSSISVLLGSGISLVQVDYKRQLVGSTMSQMGFMLVQCALGVYSAAIIHLILHGIFKATLFLQSGSIVKRFNIPKQASAKDAYGWIVMGRVLAIIVAFLFWMSSDRSAYEVLSALILGWSLLVSWNQMVAFSKGRMARLVGMILIAIVTFIYVITHNYFYAVLQNITTHATTPPTVSVIISVVILIFGSLLSIWVARHRYSKAFAVLYVWLVNLGEARSKAIESHPNYLKKYL
Protein: Glucitol operon activator protein (P15081)
Organism: Escherichia coli (strain K12)
Function: Positive regulator for glucitol operon expression.
Interaction partners:
- PTS system glucitol/sorbitol-specific EIIA component
- PTS system glucitol/sorbitol-specific EIIC component
- Sorbitol-6-phosphate 2-dehydrogenase
- PTS system glucitol/sorbitol-specific EIIB component
- Glucitol operon repressor
- Arabinose 5-phosphate isomerase GutQ
Sequence:
MVSALITVAVIAWCAQLALGGWQISRFNRAFDTLCQQGRVGVGRSSGRFKPRVVVAIALDDQQRIVDTLFMKGLTVFARPQKIPAITGMHAGDLQPDVIFPHDPLSQNALSLALKLKRG
Protein: Cartilage matrix protein precursor (Matrilin 1) (A5WWJ4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
- Fibroblast growth factor-binding protein 2b
- Actinodin2
- MIA SH3 domain-containing
- Fibroblast growth factor binding protein 2a precursor
Sequence:
MTLPGFVMLLCILGAQATVDLRQAAAMAAGLCNTKPTDVVFIVDSSRSVRPSEFEQVKVFLAKVIDGLSVGPDATRVGVVNYASRVKNEVSLKSHKTKAALVKAVSKIEPLSTGTMTGLAIQFAMNVAFSEAEGGRKSPDISKVAIIVTDGRPQDNIRDIAARAREAGIEIFAIGVGRVDMTTLRQMASEPLEDHVDYVESYSLIEKLTKKFQEAFCAVVSDLCATGDHDCEHICISTPGSFKCACREGFTLMNDSRSCSACSNAATDVVFLIDGSKSVRPENFELVKKWINLIIDKLDVSETNTHVGLVQYSSTVKQEFPLGRHNSKRSLKEAVKRMDYMERGTMTGHALSFLVDNSFGPNQGARPGVPKVGIVFTDGRSQDYIGDAAKKAKALGFKMYAVGVGNAVEDELREIASEPIADHYFYTADFKTMNQIAKKLQINVCQEEDPCECNSITKFQKKVEEALQALTKKLEAVTKRIAALENKIV
Protein: Vomeronasal type-1 receptor (Q8R279)
Organism: Mus musculus (Mouse)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU364061}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU364061}.
Interaction partners:
Sequence:
MRLPLPLEHKKMLLYQLWCSDPCLALLMLSLKCIFILHTRKEEMIWKLIKKILFLFMTMLGILGNMFVSVNFMLSWWGSPEKKSVHLILIHLAFTNIIILLTKGLQKTIVAFGLRNFLNNLGCKIIVYMERVAHGLSLCTSSLLTVVQAIIISPRASGWRRLRPKSVRHILPFFLFFWILNALISMNLINSITSTRLNISQLKSDDNYCYFMLPSQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLVLSLSSRDKTLTVNPRELLTLGYATFSPLVLIHRDGLLFECCHAQLKKLRNCLSFICSTRKKKLSVLQHCG
Protein: Protein kinase domain-containing protein (Q38AA0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MLRRIWSHKVLTTFVTLPVASVGGIAIYVEYRQRTRPVLPVFAPVVDGNGSLLLDGKAVPKPSRWVVARRVVELFLIFFPVAVLYVVMRLRRDWYLLWLQLLLRAVERAGPAFVKAGQWSCTRQDVFSPEFRSVFKKLYDEVDTHPYEVSLQILREELQQDPAEIFSTIEEKTVGSGSIGQVHSATLRHTGEHVVVKVMHPNVVETIVKDFCIINTLASFLHHRVPALEKYDLPALAIAWTTHLAAQLDFRLEARNLTLFRKNFRNEPYVRFPKPLLSTQRVLVETFCKGEPASVEFLAAQEEHARDKIANMGLNTWCKMLLHDKFLHGDMHPGNVIIDASDPHEPCVWLIDAGLCQQISEDEGVITHNLMEAFVHWKADLCCDALLSMGKRQKYADENKFRSDMNWLFNHWRPLHSKDAVVTNILQAIFECVRVNQVHMDPPYVSLLFAVLVLESFIMNLNPEFNMVRHAAPWLVADGHLTRGLMKNIVMTRLDLIKREMGVLRGRLRDGAHNDLAKNENVHLNANAW
Protein: Acyl-CoA dehydrogenase family member 11 (EC 1.3.99.-) (Q9XWZ2)
Organism: Caenorhabditis elegans
Function: Promotes adaption to elevated temperatures by regulating expression of the lipid desaturase, fat-7. Binds selectively and with high affinity to fatty acids with chain lengths from C10 to C12 and prevents them from activating fat-7 expression mediated by the nuclear hormone receptor nhr-49, leading to low levels of membrane lipid desaturation and membrane fluidity for adaption to heat.
Interaction partners:
- Probable enoyl-CoA hydratase, mitochondrial
- 3-hydroxyacyl-CoA dehydrogenase
- Trifunctional enzyme subunit alpha, mitochondrial
- Fatty acid synthase
- 3-ketoacyl-CoA thiolase
- Delta
- Long-chain-fatty-acid--CoA ligase
- Electron transfer flavoprotein subunit beta
- Hydroxysteroid dehydrogenase-like protein 2
- Probable electron transfer flavoprotein subunit alpha, mitochondrial
Sequence:
MHRIGNAVRMASSSSANATITARHTQYSHAKTGGFSQTGPTLHNPYKDDPILDRTLRRLLPESEYMRVAADLSKFGDRITSEVEHLGRQAELEQPRLEHQDAWGKRVDKLIVCNEWHKLKQICAEEGVISIGYEDSVDPFVRRIHQVAKLFLFSPSAGLVSCPMAMTDGAVKTLTSLNLYGKHKLATEAVDRLRSRDPSKAWTSGQWMTEKKGGSDVAGGCDTYAVQIDKDTYRLHGYKWFSSAVDADVALTLARIVDSDGNALEGSRGLSLFLLKIRDESGNLNGIQMVRLKNKLGTKQLPTAELLLDGAIAERIGDQGRGVAGISNMLNITRIHNAVASLGYMRRIISLARDYSTKRVVFGQTQSKWPLHTTTLAKMEVDTRGSMLLLFEAARLLGLSEAGKSSDVEAMMLRLITPVLKLYAGKQAVPMVSEGIECFGGQGYMEDTGLPTLLRDAQVTPIWEGTTNVLSLDVLRVFSGKENILLAFGKRVEQLLGNTKTEDEKLKKSKEAVESALKQLQKLLVKASDSAIQGETRIDSVARHIAFTIARIYSGALLIDHASDSSVANQSDIEVAYRYCCEQPLIDLRWEWFASERVKADREIVFDNFTALEKSKI
Protein: Cytochrome P450 26A1 (CYP26A1) (EC 1.14.13.-) (Retinoic acid-degrading enzyme CYP26) (Q9PUB4)
Organism: Gallus gallus (Chicken)
Function: A cytochrome P450 monooxygenase involved in the metabolism of all-trans retinoic acid (atRA), a signaling molecule that binds to retinoic acid receptors and regulates gene transcription. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon hydrogen bonds of atRA primarily at C-4. Has no activity toward 9-cis and 13-cis retinoic acid stereoisomers. May play a role in the oxidative metabolism of xenobiotics such as tazarotenic acid (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O43174}; Peripheral membrane protein. Microsome membrane {ECO:0000250|UniProtKB:O43174}; Peripheral membrane protein.
Interaction partners:
- Retinal dehydrogenase 2
- Uncharacterized protein
- Aldehyde dehydrogenase 1A1
- Uncharacterized protein.
- Aldehyde dehydrogenase
- NADP-retinol dehydrogenase
- Alcohol dehydrogenase 1
- Uncharacterized protein
- Uncharacterized protein.
- Cytochrome P450 family 27 subfamily C member 1
Sequence:
MGFSALVASALCTFLLPLLLFLAAVRLWDLYCASGRDPSCPLPLPPGTMGLPFFGETLQMVLQRRKFLQMKRRKYGFIYKTHLFGRPTVRVMGAENVRHILLGEHRLVSVQWPASVRTILGSGCLSNLHNGQHKHRKKVIMQAFSRDALQHYVPVIQEEVSACLAQWLGAGPCLLVYPEVKRLMFRIAMRILLGFQPRQASPDGEQQLVEAFEEMIRNLFSLPIDVPFSGLYRGLRARNIIHAKIEENIRAKMARKEPEGGYKDALQLLMEHTQGNGEQLNMQELKESATELLFGGHETTASAATSLIAFLGLHHDVLQKVRKELQLKGLLSGPNQEKQLNMEFLEQLKYTGCVIKETLRLSPPVPGGFRIALKTLELNGYQIPKGWNVIYSICDTHDVADLFTDKDEFNPDRFMSPSPEDSSRFSFIPFGGGLRSCVGKEFAKVLLKIFTVELARSCDWQLLNGPPTMKTGPIVYPVDNLPAKFIGFSGQI
Protein: KH RNA binding domain containing, signal transduction associated 3 (E5RJZ9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MEIEKFQKGEGKDEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYST
Protein: STARD3 N-terminal like (C9J3F5)
Organism: Homo sapiens (Human)
Subcellular location: Late endosome membrane {ECO:0000256|ARBA:ARBA00004107}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004107}.
Interaction partners:
Sequence:
MNHLPEDMENALTGSQSSHASLRNIHSINPTQLMARIESYEGREKKGISDVRRTFCLFVTFDLLFVTLLWIIELNVNGGIENTLEKEVMQYDYYSSYFDIFLLAVFRFKVLILAYAVCRLRHWWAIALTTAVTSAFLLAKVILSKLFSQGAFGYVLPIISFILAWIETWFLDFKVLPQEAEEEN
Protein: Extracellular matrix protein (Q54LF5)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Extracellular matrix protein A
- Prestalk protein
Sequence:
MKLLYSLVALLGVSSVAFGDTSCNQLLSSLADPSKCVQVSISGVHYQSLAQEGYKGNLVFASGEFVLRESLYNLQTYETTCSSRGLVQPFAADYQFRVDDFSIRLSDGNLRLKQTNTQLTCNGNVGFFNLNNFYYTVALKSYDTCPKLNYGEPCNTPTVTPTVTPTPTVAPTTPPVGTPKINYKLDTDSNWVANGVTYYQYKVTLTNNESSPIKSIEIHSDNWNPTEFWNIVRSQKTGNLSFPPFVVNLQAGDSFSFGFVSATLNPSFSTVKIVKA
Protein: Malate dehydrogenase (EC 1.1.1.37) (Q5AMP4)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- Citrate synthase
- fumarate hydratase
- fumarate hydratase
- Transaminase A
- Pyruvate carboxylase
- Aspartate aminotransferase
- Aspartate aminotransferase
- malate dehydrogenase
- Phosphoenolpyruvate carboxykinase
- Malate synthase
Sequence:
MFSKVATRSFSSSASNAYKVAVLGAGGGIGQPLSLLLKLNHKVTDLALYDIRGAPGVAADVSHVPTNSTVKGYNPDQIEEALTGSDVIVIPAGVPRKPGMTRDDLFNTNASIVRDLAKAAADYAPNAAVCIISNPVNSTVPIVAEVFKSKGNYNPNKLFGVTTLDVLRAARFVSEVAGTNPVNENVPVVGGHSGVTIVPLLSQTKHKDLSGETRDALVHRIQFGGDEVVQAKDGAGSATLSMAQAGARFAGAVLDGLAGEKDVIECTFVDSPLFKDEGVDFFSTKVTLGVDGVKTVHPIGEISDYEEAQVKEAKDTLIKNIKKGVDFVAQNP
Protein: Eukaryotic translation initiation factor 2-alpha kinase 2 (EC 2.7.11.1) (Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase) (Heme-regulated inhibitor 2) (Q9UTE5)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Mediates down-regulation of protein synthesis in response to stress conditions by the phosphorylation of the alpha subunit of eIF-2 (tif211) on 'Ser-52'. Protein synthesis is inhibited at the level of initiation. Activity is inhibited in the presence of heme.
Interaction partners:
- Eukaryotic translation initiation factor 2 subunit alpha
- eIF-2-alpha kinase GCN2
- Eukaryotic translation initiation factor 2-alpha kinase 1
- Elongation factor 3
- ATP phosphoribosyltransferase
- mRNA export factor elf1
Sequence:
MRFFNAHKSAEDGNYSETTNAISLKNERQSRDLSVNKHGRMLLTALLENFCQLYDNNPAKSKRLFALICHTLQKIGILEEEYIEELAAVRSNYQDALHHLILQAREAIRLDDAEERLLALPDPTNVFEKFPQETALSKFSVDGLNVRQFRFRDLTLESWLQSRNSRYIEDFEEYSLLGRGGFGSVYHVRNKIDGAEYAMKKINSTFQQMSYSKIFREIKCLAKMDHPNVIRYFSSWVESTTEATQMPIVMSKNSSRVLGTSSYCDVNGMDSIIFEPTESSALTDDILFAEDPGTESIISTSRKSSYSSTTESSNFENLESPRNLHDSNVSTFNNTTILDDDYSSSMHISKTGPTHSFIIYIQMQLCFDDLESYLIRRNHFLSFPLCKEQIQLHTDLFRMIINGVMYVHEGVNLIHRDIKPSNIFLAKSLPEDRGSVPLISYNDKNDLKEYITPKIGDFGLVVENKKNTETALSFLERNHLPNLQDETQHIGTATYAAPELLDAMSSQHNKFTKKIDTFSLGMVLFELLHPFQTNMERATKLQDLRRGNLPEEFVEQHICESSLILWMTAKDPTKRPSLLEVLNCGLLLPNQVSMPNISNIVSTNHLDVETQMKLIMDENQRLREQIAVLRSRIQHLETR
Protein: Retrotransposon hot spot (RHS) protein, putative (D7SGA3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSRANSPAAPQGNNENQQVADNFEGPMRRPRDENVPPPPPPAAAAAAQPPQIRQRTEGGPNWTMDSKVRDVLLDDYAGLRNLTLHDFLLKKFLNTYNTENVAMDVFVQSPGDYILDAGILERIQRLYQFEEYKELYDQFSEMKRKARYLDEKEIYYLSQWEEKGTVEIREFVGPVARGRLDGAVTAAKRAEKRAAQTADGSELKGVYDSIYNATWSYVESGHDTEPLGMKVFNGRPPHMWTKEEVDVSHTPETMNEPLPRHGNLEIAVLTSQMGWPYTSFEKNPNDYDINHEKGVEYVFKSDVYIRREALRVWYKVENVLNRWLMDEVIVDDASNVLIGTPGIGKSFSVGSLLLYKLLHYEASQLQIIIYVVRGKAYVFHKPIGGRAGYVTFYNDYGNAFTVVEQIIGGSRSGEDIKGYVIFDVDKDHPAPTKPPAGCAGIALSSPNVKQFHEWSKQNTASDIYMNCDTLKDLEAIHISRWGKIAPAYKWSPPVAKEKIESEWQEIQARIRIVGPLLRHIGRLSSYNRQEGKVQEAIGKMKDDDMNDYAKYFQNAAMWQTDEVSHKLVGVVRVKEEKLLCEMYRCRPLSSYTGQAILDFLIPWLTDKYAAMSALLSNRAIAAYMFEKSGIEALSHENTLTELARELQGLSFARNQIPQSVLQVLQEPRLIGPSIVVPEDVPIVAGAEIQYMKLYKPQSRSFPVVDAFFFVESPKTFVGLQYTVSGRHPCSTGGLFKMKRYLRSYFQGWDNFSNDMVWEIIYVQRVDSEKITKPQCCERTDRDEGQNNEVEERFWKREVRQFAVSLYKHIIALYVELKTRGENNNGVNNRGGNNA
Protein: Stonin-2 (D4AB66)
Organism: Rattus norvegicus (Rat)
Function: Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating (By similarity).
Subcellular location: Synapse, synaptosome {ECO:0000269|PubMed:21102408}. Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}. Note=Some fraction is membrane-associated. {ECO:0000250}.
Interaction partners:
- Epidermal growth factor receptor pathway substrate 15
- Synaptotagmin-1
- Intersectin-1
- Synaptotagmin-2
- Epidermal growth factor receptor substrate 15-like 1
- Disabled homolog 2
- Clathrin coat assembly protein AP180
- FCH and mu domain containing endocytic adaptor 1
- Intersectin 2
- Vesicle-associated membrane protein 2
Sequence:
MTTLDHVIATHQSEWVSFSEEPLFPTPLEGGTEEHFPGLSSSSDRSESSSGENHAVDEGSQDLSHSEQDDSSEKMGLISEAASPPGSPVQPTPDLASAISNWVQFEDDTPWSNTSAPHKETALTLTVPCWTCPSLDSLRRCPLASESSWTTHSEDTSSPSVAPSYTDLQLINAEEQASGRASGTDSTDNSSSLQEDEEVEMETISWWAGSPAMNGHPAVPQVTTARFPSWVTFEDNEVGCPSPTVPSPKKPNAPSAATAGPDVPFNSTGSFKRDRPKSTLMNLSKVQKLDISSLNRPPSVTEAPPWRATNPFLNESLQDIQPSPINPFSAFFEEQERRSQNSSISGTSGKSQRDSLIVIYQDAISFDDSGKSQSHPDAIEKLKQLQIDDPDPVGNAALPDDDPTASVEPDAPSPTSALSQPRDGWPMMLRIPEKKNIMSSRHWGPIYIKLTDSGYLQLYYEQGLEKPFREFKLEICHEVSEPRLQNYDENGRIHSLRIDRVTYKEKKKYQPKPAVAHAAEREQVIKLGTTNYDDFLSFIHAVQDRLMDLPVQSMDLSTVGLNYLEEEITVDIRDEFSGTVSKGDNQILQHHVLTRIHILSFLSGLAECRLGLNDILIKGNEIVSRQDIMPTTTTKWIKLHECRFHGCVDEDVFNSSRVILFNPLDACRFELMRFRTVFAEKTLPFTLRTAASINGAEVEVQSWLRMSPGFSSNRDPLTQVPCENVMVRYPVPSEWVKNFRRESVLGEKSLKAKVNRGASFGSAGASGSEPVMRVTLGTAKYEHAFNSIVWRINRLPDKNSASGHPHCFFCHLELGSDREVPSRFANHVNVEFSMPTTSASKAAVRSISVEDKPDVRKWVNYSAHYSYKVEIEQKKSLKPDFEGEDLENPKECGVQ
Protein: Protein DA1 (Protein SUPPRESSOR OF LARGE SEED AND ORGAN PHENOTYPES OF DA1-1 1) (P0C7Q8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Ubiquitin receptor that limits final seed and organ size by restricting the period of cell proliferation. May act maternally to control seed mass. Acts synergistically with DA2 to regulate seed size. Functions synergistically with DA2 to restrict cell proliferation in the maternal integuments of ovules and developing seeds. Functions antagonistically in a common pathway with UBP15 to regulate seed size. Associates physically with UBP15 and modulates the stability of UBP15, which promote cell proliferation in the integuments of ovules and developing seeds. Functions as peptidase and cleaves the N-terminal sequence of E3 ubiquitin-protein ligases BB and DA2 in a ubiquitin-dependent manner. Cleaves the deubiquitinating enzyme UBP15, which promotes cell proliferation, and the transcription factors TCP15 and TCP22, which promote cell proliferation and repress endoreduplication. Involved in the promotion of leaf senescence, in addition to its function in restricting plant growth. Acts redundantly with DAR1 and DAR2 to regulate endoreduplication during leaf development. Together with DAR1 and DAR2, modulates the protein stability of the transcription factors TCP14 and TCP15, which repress endoreduplication by directly regulating the expression of cell-cycle genes.
Interaction partners:
- HSP20-like chaperones superfamily protein
- AT3g15090/K15M2_24
- DEAD-box ATP-dependent RNA helicase 28
- Protein BOBBER 2
Sequence:
MGWFNKIFKGSNQRLRVGNNKHNHNVYYDNYPTASHDDEPSAADTDADNDEPHHTQEPSTSEDNTSNDQENEDIDRAIALSLLEENQEQTSISGKYSMPVDEDEQLARALQESMVVGNSPRHKSGSTYDNGNAYGAGDLYGNGHMYGGGNVYANGDIYYPRPITFQMDFRICAGCNMEIGHGRFLNCLNSLWHPECFRCYGCSQPISEYEFSTSGNYPFHKACYRERYHPKCDVCSHFIPTNHAGLIEYRAHPFWVQKYCPSHEHDATPRCCSCERMEPRNTRYVELNDGRKLCLECLDSAVMDTMQCQPLYLQIQNFYEGLNMKVEQEVPLLLVERQALNEAREGEKNGHYHMPETRGLCLSEEQTVSTVRKRSKHGTGKWAGNITEPYKLTRQCEVTAILILFGLPRLLTGSILAHEMMHAWMRLKGFRTLSQDVEEGICQVMAHKWLDAELAAGSTNSNAASSSSSSQGLKKGPRSQYERKLGEFFKHQIESDASPVYGDGFRAGRLAVHKYGLRKTLEHIQMTGRFPV
Protein: Glycine hydroxymethyltransferase (Serine methylase) (G3V4W5)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTT
Protein: Palmitoyltransferase (EC 2.3.1.225) (Q9VBM7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Uncharacterized protein, isoform A
- Palmitoyltransferase
- Palmitoyltransferase
- Palmitoyltransferase Hip14
Sequence:
MCLIWACTKYLARRNPKIFVRISHPTAVLFVIVTTIFFVVLQMFYVVPQLFDVQGFMYKLGWLVAIFITYNIFGNMLACHITSTSVESLPKDRQIPEPEEEHQWHYCDVCEKLMPPRSWHCILCKCCILKRDRHCIFTASCVGHNNQRYFFWFTLFMALGTGVALATHIIATLKYFSYSDLIFLNIPRDNLPPFWLVITLILNTYVFAAPVSSVLMQLSVLKNNGTLHKFYSDTYDLGLWENFKLILGGKGFWTFLSPTVKSPLPHDGAQWKIKRVQHHSPKLQFLRVSD
Protein: Putative RNA-binding regulatory peptide (RBRP) (Septin 14 pseudogene 20) (C0HM01)
Organism: Homo sapiens (Human)
Function: Enhances binding of IGF2BP1 to N6-methyladenosine (m6A)-containing mRNAs, thereby contributing to increased mRNA stability. Also increases the interaction of IGF2BP1 with RNA stabilizers ELAVL1/HUR, MATR3 and PABPC1, and increases the interaction of RNA stabilizers ELAVL1/HUR, MATR3 and PABPC1 with m6A-containing mRNAs. Contributes to MYC stability by enhancing binding of IGF2BP1 to m6A-containing MYC mRNAs and increasing recruitment of RNA stabilizing proteins to m6A-containing MYC mRNAs.
Interaction partners:
Sequence:
MIQQEEIRKLEEEKKQLEGEIIDFYKMKAASEALQTQLSTDTKKDKHPDPYEFLLLRKIKHPGFNEELSPC
Protein: Candida glabrata strain CBS138 chromosome C complete sequence (Q6FWP8)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
Interaction partners:
Sequence:
MSLLARYLLQRRVKRYSVLFVLFVGLFIFIARHLTNEEESDNGIYKDDKFPYEDGLLHSSSNSAYTFITDAMNKLTKKKKNSFLSPKGLSYFKDDERILKNWNTSSRVDKCKWLIRGIYADPNWNNRDILIGSDETNDKNKFHLSSERIRIHNYCFMKERIDPVQMFNELNISSTDAYDFQGRMFMFLRNVTSTDEAYIYPIIKNVRNGQVTTKPHTKLSPMQYNSNFMAYWKQESKGRGIALTAAPKDVKLLRSLFKVFEKLGNTYPIQIVQKGGEMSPTMESLIKDYAIETNQNVFIVDLSPVLDPDFATDHIRKFQNKWFASIFNTFEEVMLIDADVVIYTEPESFFNLDGYKNTGLLLWRDREIVDAKTHERCTDMAPYFEPALEEHRLLGTVQKYRLTGPSLETHDEPEAETLFDFFHRRIVTIIDSGVVIYNKKQKLHGLILAEYFHNSKQFAGCVYGDKEYFEFGALVAGEDYHVEAEKAVAIGAVGYHPPREKYYVCSGQMGHVDRNNNLLWSNGGLKNCKSDCAEADFEKMPKYFKAKYGTLKAVKEYYNGLMDIQGFVLPDVQKQKWVQYPDCQQFLYCAFITDPPEPDNKGKLVRFSDEEKMRYNEIGKAWYSGAND
Protein: histidine kinase (EC 2.7.13.3) (Q9HT87)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- Alginate biosynthesis transcriptional regulatory protein AlgB
- Two-component response regulator
- Transcriptional activator protein PfeR
- Probable two-component response regulator
- Transcriptional regulatory protein GltR
- Protein PilH
- Transcriptional regulatory protein AruR
- Probable two-component response regulator
- Two-component response regulator CreB
- Two-component response regulator, ParR
Sequence:
MSMPLPMKLRTRLFLSISALITVSLFGLLLGLFSVMQLGRAQEQRMSHHYATIEVSQQLRQLLGDQLVILLRETPDGQALERSQNDFRRVLEQGRANTVDSAEQAALDGVRDAYLQLQAHTPALLEAPMADNDGFSEAFNGLRLRLQDLQQLALAGISEAETSARHRAYLVAGLLGLVGVAILLIGFVTAHSIARRFGAPIETLARAADRIGEGDFDVTLPMTNVAEVGQLTRRFGLMAEALRQYRKTSVEEVLSGERRLQAVLDSIDDGLVIFDNQGRIEHANPVAIRQLFVSNDPHGKRIDEILSDVDVQEAVEKALLGEVQDEAMPDLVVDVAGESRLLAWSLYPVTHPGGHSVGAVLVVRDVTEQRAFERVRSEFVLRASHELRTPVTGMQMAFSLLRERLDFPAESREADLIQTVDEEMSRLVLLINDLLNFSRYQTGMQKLELASCDLVDLLTQAQQRFIPKGEARRVSLQLELGDELPRLQLDRLQIERVIDNLLENALRHSSEGGQIHLQARRQGDRVLIAVEDNGEGIPFSQQGRIFEPFVQVGRKKGGAGLGLALCKEIIQLHGGRIAVRSQPGQGARFYMLLPV
Protein: Photoactivated adenylate cyclase subunit beta-like protein 1224-5/9F (P84740)
Organism: Euglena gracilis
Subcellular location: Cell projection, cilium, flagellum {ECO:0000269|PubMed:16121285}. Note=Paraxonemal body. And paraxonemal bodies (PABs).
Interaction partners:
Sequence:
MYILVWKKGQQIKTFHTLDEAAQFKAASNFDEAPMFSVTVAPAISASGGSNEATNLRRLMYLSKGTNPEECNPQFVAELARVATIRNREIGLSGFLMSSSPFLFQAIEGTDQDLDFLFAKISADPRHERCIVLANRPCTGRMSGVWHMKDSHMDSITTHDAMMTILYQIARSFSSMLTYLPKRAGNMLLSGLDPAAQPPEPKSVVVTFIYLVAYGSLLSNPYSTEQPAEVLSTFVDVCVKNLEGSGGIITKFITGICMASWPFNRTEEALTAIQQISEDLAQLPSQQAPGSSPSLMYSQAGVHYGRAMLCNAGSGKSDFTLLGDWINTTSRIATLAKKLTSPVLFSFQVRCLLGDEMREEIEGAVMDQVKGRDKPVVEYQFPGPERDVEVVGQKIEQFTPGRFRCQMRVGQYEALPISQRPPIFDDTPKCNPRPRTPGCEGRQRSHTLVDPHIMMAKLPGPSVSATGDTTVPTLTYISHATRPMSRLDLSAIMGTATRINALQRITGTLLHGNGLFVQTQEGPKEAEINLLLRIRQDTRRSDVATDHMPQPQERVYPSEWTLTSGKEEILAIFPPLQDVLSRLAKSFTAQETYVPSRVVSYLTAGNNPRELMPVSCGVVMTDICSLTSLTENSCLSEVWMICNTFIDACPSAICQEGAEVIKLIGNCVTAYFPGNNADSAVASAQELFTFCREHRQAIVDVLDVRGCVSYGVALDNGQVVMAQCGSEGLTEYVVAGAVSARVMEVEAITRGTCPRWATPLWSADRLSPQLRDHGIVPTPQAIEGLPCYGIAGEEFELDVDSIKLGIKALHAARSGEKPLTEPEEAKLDFSPGRVRHGDSGRRSNSAQGKLSIQVR
Protein: Pyridoxal kinase (EC 2.7.1.35) (Pyridoxine kinase) (O00764)
Organism: Homo sapiens (Human)
Function: Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively (Probable). PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:9099727}.
Interaction partners:
- Pyridoxine-5'-phosphate oxidase
- Chronophin
- Aldehyde oxidase
- Pyridoxal phosphate phosphatase PHOSPHO2
- Pyridoxal phosphate homeostasis protein
- Thyrotroph embryonic factor
- Adrenodoxin, mitochondrial
- Ferredoxin-2, mitochondrial
- EKC/KEOPS complex subunit TP53RK
- Proliferating cell nuclear antigen
Sequence:
MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSDELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKWDGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGPDTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAMLLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDIEDPEIVVQATVL
Protein: Zinc finger CW type with PWWP domain 1 isoform 6 (A0A0S2Z6A9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGSGLDFAETSCAQPVVSTQSDKEPGITASATDTDNANGEEVPHTQEISVSWEGEAAPEIRTSKLGQPDPAPSKKKSNRLTLSKRKKEAQDEKVEKTQGGHEHRQEDRLKKTVQDHSQIRDQQKGEISGFGQCLVWVQCSFPNCGKWRRLCGNIDPSVLPDNWSCDQNTDVQYNRCDIPEETWTGLESDVAYASYIPGSIIWAKQYGYPWWPGMIESDPDLGEYFLFTSHLDSLPSKYHVTFFGETVSRAWIPVNMLKNFQELSLELSVMERVNLFGFWSRFNGSNSNGERKDLQLSGLNSPGSCLEKKEKEEELEKEEGEKTALRKNLKLPRARPWQPAFQREKKLEQCQRTWAYQRVRGPAPHLRKKSPDTGNP
Protein: Candida glabrata strain CBS138 chromosome H complete sequence (Q6FRK3)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Interaction partners:
- Phosphoribosylaminoimidazole carboxylase
- Amidophosphoribosyltransferase
- Phosphoribosylglycinamide formyltransferase
- Phosphoribosylformylglycinamidine synthase
- Adenylosuccinate lyase
- Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Candida glabrata strain CBS138 chromosome A complete sequence
- Methylenetetrahydrofolate dehydrogenase [NAD
- Glycine cleavage system P protein
- Adenylosuccinate synthetase
Sequence:
MLNILVLGAGGREHALVWKLVQSPSVEHIYVAPGNGGIAKIGPKVVCVDIDCDAKNFEKLREFAVSKDINLVVPGPEVPLIDGVTDLFAKVGIPVFGPSAKAAQLEGSKGFSKDFMQRHNIPTARHKTFESYEEAKRHLEEVNYRVVLKADGVAAGKGVLIPENKEEALKALDVIMVEKQFGDAGNTVVIEEFLEGDEISILTISDGYSYFNLPPAQDHKRIGENDTGLNTGGMGTYAPAPVATPKILQEVDSTIIKPSIDGFRKERIPLVGCLFTGIILTKEGPRVLEYNVRFGDPETQSVLPLLTEDTDLAEVFLAAAEHRLDSVEIKTKSDCFATTVVLSAGGYPESYKKGDIITIDEKKLPFDSYVFHAGTALDAQGNLITNGGRVIAASAVSDTLKGAVDKAYEAVEGIQFEGRYFRKDIAHRAFRDTENKSQGITYADAGVSVDNGNLFVEKIKNMVKSTRRPGADSDIGGFGGIFDLKQAGYNTDDTLLIGATDGVGTKLIIAQETNIHDTVGIDLVAMNVNDLVVQGAEPLFFLDYFATGALDIKIAADFVSGVAEGCIQSGCALVGGETSEMPGMYPPGHYDTNGTAVGAVQKDSVLPMTNLMKEGDVLLGLASDGVHSNGFSLVRKVISHVGISWSEQCPWEPSKTLGEAILTPTRIYVKQLLPSIREKLILGLAHITGGGLVENIPRALPKHLQAQVDMSNWSVPEVFKWFGKAGNIPVDDILKTFNMGIGMVIIVDKANVARVKELLEQANETVYEIGSLVNRLEGQPGCVVNNASNLY