wanglab/gogpt-training-data huggingface dataset:
Protein: Malonate-semialdehyde dehydrogenase (EC 1.2.1.27) (3-oxopropanoate dehydrogenase) (Q9I702)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Involved in the degradation of beta-alanine.
Interaction partners:
- Beta-alanine--pyruvate aminotransferase
- Beta-alanine degradation protein BauB
- Probable GABA permease
- Probable AMP-binding enzyme
- Citrate synthase
- 3-hydroxyisobutyrate dehydrogenase
- Acetyl-coenzyme A synthetase 1
- Acetyl-coenzyme A synthetase 2
- Uncharacterized protein PA3568
- Probable pyridoxal-dependent aminotransferase
Sequence:
MGTLHHLINGEMVADNGRSADVFNPSTGEAIHKVPLADGKTLQKAIDAARAAFPAWRNTPPAKRAQVLYRFKQLLEQNEARISKLISEEHGKTLEDAAGELKRGIENVEYACAAPEILKGEYSRNVGPNIDAWSDFQPIGVVAGITPFNFPAMVPLWMYPLAIACGNTFILKPSERDPSSTLLIAELFHEAGLPKGVLNVVHGDKEAVDGLLQAPEVKAISFVGSTPIAEYIYAEGTKRGKRVQALGGAKNHAVLMPDADLDNAVSALMGAAYGSCGERCMAISVAVCVGDQVADALIAKLVPQIKALKIGAGTSCGLDMGPLVTAAAQAKVTGYIDSGVAQGAELVVDGRGYQVAGHENGFFLGGSLFDRVTPEMTIYKEEIFGPVLCVVRVNSLEEAMQLINDHEYGNGTCIFTRDGEAARLFCDEIEVGMVGVNVPLPVPVAYHSFGGWKRSLFGDLHAYGPDGVRFYTRRKAITQRWPQRASHEASQFAFPSL
Protein: Translocon-associated protein subunit alpha (TRAP-alpha) (Signal sequence receptor subunit alpha) (SSR-alpha) (P45434)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.
Subcellular location: Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Interaction partners:
- Translocon-associated protein subunit beta
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
- Protein transport protein Sec61 subunit beta
- Translocon-associated protein subunit alpha
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
- Calnexin homolog 1
- Calnexin homolog 2
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1B
- Syntaxin-31
- Syntaxin-32
Sequence:
MMNLRVLFLALLLLASPLLQVARCQSDAEDHSSLVDDVVGENTDDAVEEDDHDLDMNLSSFPGVETVCVFPKNSAKLVPAGEETELLVGLKNEGKTRVGVMGIRASVHLPYDHKLLVQNLTMLRLNNASIPTSLQATFPYIFAVSQYLQPGAFDLVGYIIYDVEGKPYQSVFYNGTIEVVESGGLLSGESVFLLTLGIGLLLLLGLWAYSQVQRLTKKTKKVSKVEVGTRSTEASLDEWLEGTTLAKTSSGKTKNKKN
Protein: Homeobox domain-containing protein (Q86DC2)
Organism: Caenorhabditis elegans
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
- SET domain-containing protein
- Late nodulin
- C2H2-type domain-containing protein
- Sop-2-related protein 3
- Homeobox protein ceh-31
- Homeobox domain-containing protein
Sequence:
MNRSNEFEWKIPKLEEPENIQDVNLFEETEPEKFTKGYIKEELPDKICSTVRKVIKIPRSALEKVGVRLHDDEQKPTHLLSDDIKTEPIEEATHVNVIQTPSWKPKFQCISDLLKDDTTDFDCEMSLGSSVLFDRPDSSLPIKKICPGFPKKVGSIPSNKRIMSESQVRRELNASFARNCHPTAIGMQKLSERCGIRYKTIFDNFETIRKDGKIECETNDACCRIREFLSRETDTTSYIEITNEVQTVLEDEIELHLLSRKRFTLGYVHVIMEKTDLAPSYIRAQYENWRRKLSTKDRGSWKIGDSEAENSVLSAEVSKQLEEAFLQRTNNREDKTLRPKDIKALSTQLEINEKEIENWIAKKTEATSGSNSTEQQQKHNILRIFASCRRRLPKLNIEGLNKYFAKNNKPGVRQREKIAKKLGLSERQVRNYFNKKRITERKLKVWKDAPKDFLTLSKQTVDEMMKIAEERRKPNDEYIQIANRLGVSHITLCSFIDWQKSIYAGKAK
Protein: Glycogen synthase kinase-3 beta (EC 2.7.11.26) (I6ZX61)
Organism: Sus scrofa (Pig)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPSNATAASDTNAGDRGQTNNTASASASNST
Protein: Protein DA1-related 1 (Q8W4F0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts redundantly with DA1 and DAR2 to regulate endoreduplication during leaf development. Together with DA1 and DAR2, modulates the protein stability of the transcription factors TCP14 and TCP15, which repress endoreduplication by directly regulating the expression of cell-cycle genes.
Interaction partners:
- Transcription factor TCP14
- Uncharacterized GPI-anchored protein At5g19240
- Transcription factor TCP15
- LIM domain-containing protein WLIM2a
- Ubiquitin carboxyl-terminal hydrolase 15
- E3 ubiquitin-protein ligase DA2
- Uncharacterized GPI-anchored protein At5g19230
- Uncharacterized GPI-anchored protein At5g19250
- E3 ubiquitin-protein ligase BIG BROTHER
- LIM domain protein
Sequence:
MGWLTKILKGSSHKFSDGQCNGRYREDRNLEGPRYSAEGSDFDKEEIECAIALSLSEQEHVIPQDDKGKKIIEYKSETEEDDDDDEDEDEEYMRAQLEAAEEEERRVAQAQIEEEEKRRAEAQLEETEKLLAKARLEEEEMRRSKAQLEEDELLAKALQESMNVGSPPRYDPGNILQPYPFLIPSSHRICVGCQAEIGHGRFLSCMGGVWHPECFCCNACDKPIIDYEFSMSGNRPYHKLCYKEQHHPKCDVCHNFIPTNPAGLIEYRAHPFWMQKYCPSHERDGTPRCCSCERMEPKDTKYLILDDGRKLCLECLDSAIMDTHECQPLYLEIREFYEGLHMKVEQQIPMLLVERSALNEAMEGEKHGHHHLPETRGLCLSEEQTVTTVLRRPRIGAGYKLIDMITEPCRLIRRCEVTAILILYGLPRLLTGSILAHEMMHAWLRLNGYPNLRPEVEEGICQVLAHMWLESETYAGSTLVDIASSSSSAVVSASSKKGERSDFEKKLGEFFKHQIESDSSSAYGDGFRQGNQAVLKHGLRRTLDHIRLTGTFP
Protein: Fatty acid desaturase 6 (EC 1.14.19.-) (Q8N9I5)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Delta-1-pyrroline-5-carboxylate synthase
- Adrenodoxin, mitochondrial
- Ferredoxin-2, mitochondrial
- Voltage-gated monoatomic cation channel TMEM109
- Electron transfer flavoprotein subunit beta
- Glutamyl-tRNA
- GMP synthase
- Isoamyl acetate-hydrolyzing esterase 1 homolog
- Thymidine phosphorylase
- Glutamate dehydrogenase 2, mitochondrial
Sequence:
MEPTEPMEPTEPMEPTEPMEPARSAHRGGEALLRELEVLVQDVVRTSSWWERHGVDCAILALSLFALPAGFLCLRWENALVFASGITILGVCHYTLTVKGSHLATHGALTESKRWSKIWLLFFVEVCTAFTAEHATHGHVKMHHAYTNVVGLGDSSTWRLPCLNRYVYMFLAPFLLPIATPLVAVERLRKVELGTALRTLALISLGLYSHYWLLLNVSGFKNPSSALGCMFLTRSLLAHPYLHVNIFQHIGLPMFSRDNKPRRIHMMSLGVLNLARLPVLDWAFGHSIISCHVEHHLFPRLSDNMCLKVKPVVSQFLREKQLPYNEDSYLARFQLFLRRYEEFMVQAPPITELVGL
Protein: Zinc-finger protein at 72D, isoform B (Zinc-finger protein at 72D, isoform C) (Zinc-finger protein at 72D, isoform D) (Zinc-finger protein at 72D, isoform F) (Q86BI3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Interleukin enhancer-binding factor 2 homolog
Sequence:
MANNNYAGFNYGGTQYNTGQVSYPAVTNATYANAAAYQNAAVAAGQGGYGGAAGAGAGATSGPGAGGYGGYGDYRSAMQYDATKTFYQQSPASYNASGSTASVSKTHYSAPPVKNQVKGKMDKSNGGPKPPSSAPPAGNNYSGYDTALYNAASMYVAQQHQGNPNQKPNGGANNWYQRKMGATIPGATAIRGMRPKAPPRPQQLHYCEVCKISCAGPQTYREHLEGQKHKKREASLKMSASANSATQNRGNNYHCELCDVTCTGTDAYAAHVRGAKHQKVVKLHQKLGKPIPSEEPKKMGKINFVPAAAGGAGVAKTEGGANESDAAGDLDDNLDDSLGENTDNIKPVGGEYIEEVKDEEGKILSFNCKLCDCKFNDPNAKEMHMKGRRHRLQYKRKVQPDLVVDFKPTPRQRRLAEARANRAMMSSHRGGDDHDGGYWEEQRNRQYNEEYDYNNWMSRSFGGAQRFGRMGNGPPPHFGMMPGGNVRRPESTDDRHAIARHAEIYPKEEELQTIQRIVSHTERALKLVSDALAEQPSDAGAANKKDKAEKPSEKDGRDNQIFSFQKDADNGGNVVRILKGVMRVGYLAKGLLLHGDNAVELVVLCAEKPTSGLLQRVANVLPDKLKEVAGDTQVNYRVEVNAEEAALIVLDESVSVKITLTSPLLRDANPGEAATTDEGEGDSEFLPREPCLRALADLRHAKWFQARATGLQSCVMVIRILRDLCQRVSSWQSLPQWSLELLVEKVISSAGFPISPGDCMRRIMEALSSGFLINGPGLLDPCEKDPTDALLELTKQEREDLTVSAQLFLRYIAFRQIYKVLGMEPLPAMKFPMRPWRVNRKRRRSSGKAGGAPGTETESNDIDETGSDEKVAKKEGVGGTPAST
Protein: Caspase-8 (H7C0E2)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
NLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKGALTTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD
Protein: AP-3 complex subunit delta (Adaptor-related protein complex 3 subunit delta) (Delta-adaptin 3) (Delta-adaptin) (Q9UTL8)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole (By similarity).
Subcellular location: Golgi apparatus {ECO:0000250|UniProtKB:Q08951}. Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000250|UniProtKB:Q08951}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q08951}; Cytoplasmic side {ECO:0000250|UniProtKB:Q08951}. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. {ECO:0000250|UniProtKB:Q08951}.
Interaction partners:
- AP-3 complex subunit beta
- AP-3 complex subunit mu
- AP-3 complex subunit sigma
- AP-2 complex subunit mu
- AP-2 complex subunit sigma
- AP-1 complex subunit sigma-1
- AP-2 complex subunit beta
- AP-1 complex subunit beta-1
- AP-1 complex subunit mu-1
- AP-2 complex subunit alpha
Sequence:
MVFERTLIDLIKGIRSHANDEEAFIATCLLECRKEATSQDADLKSEAILKLAYLEMLGVDISWASFQIVEVMSSSKILQKQKGYLAAVQSFKPDTDVLMLTTNLLKKDLMSSKVPEITLAIDGLSHFSTLGLARDLYRDVLILLNHSVPYVRKRTILLLYRLCLQYPEAISACIPKLRERLDDPDTSVVNAAVSVICELARRAPKNYLEFAPDLFHLLTTSSNNWMLIKLIKLFASLTPYEPRLVKKLIPSLTDIIENTHAMSLLYECINTIVSGNMLVGHSQCDKLASLCASKLRGFFEDTDQNLKYIALLCLRKLANTHPSLVSAQLDIILKCLVDTDTSIRLRALDLVNEIVNKENIRTIVKTLMLQLIVSSDESAVEDIRNSTATRIIEMTSKSTYMNIADFEWLLTVYVDLANIPGIDTGTLLNNQIIDLCVRVKALRPFSVDIFSQAILDPSYVSTTDCSVSEKRTDILPAIIWCLGEYAEFIEEYLDILDALTRPSFKKCSNLAHRLLLQAITKIFCQWCLEEEPTWGVEKFGLVKLWVEKIVSFIEQFLNFQDMEIQRRASEFYILFNQVSDIVNTSDTMEVLELQKKPPYIVQNTMYKLFFGEPLNPVAVKAQRKVMPDENLDLNCPINGVIEVPKELLENIIQSDDSLINFDTEVPSSGIDTFSKKQFNSLESVPVQRDLSSPFYLSSNQHTTTTNSEPENLNVETSMSDEAFNADKVTKVTKNKRRRKIFTSPSLQAMVVAQDEVPEGISLADIENKENPSNSNVYSLISLDPPLSTNQGSMGDIVLETKSPIRVEKKKSKKKKKKKEKTSGKE
Protein: Ankyrin 2 (A0A5F9ZH35)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MTTMLQKSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEGDDTMTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSSDRSHTLSHASYLRDSAVMDDSVVIPSHQVSTLAKEAERNSYRLSWGTENLDNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVTFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFAEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYTKESESDQEQEEEIDMTSEKNPQDEQERIEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTNLVECLTKINRMDIVHLMETNTEPLQERISHSYAEIEQTITLDHSEGFSVLQEELCTAQHKQKEEQAVSKESETCDHPPIVSEEDISVGYSTFQDGVPKTEGDSSATALFPQTHKEQVQQDFSGKMQDLPEESSLEYQQEYFVTTPGTETSETQKAMIVPSSPSKTPEEVSTPAEEEKLYLQTPTSSERGGSPIIQEPEEPSEHREESSPRKTSLVIVESADNQPETCERLDEDAAFEKGDDMPEIPPETVTEEEYIDEHGHTVVKKDNNE
Protein: Espin (B0S4T9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell projection, stereocilium {ECO:0000256|ARBA:ARBA00004645}.
Interaction partners:
- Myosin IIIB
- Myosin IIIA
- Whirlin b
- Whirlin
- Plastin 1
- Twinfilin-2
- TRIO and F-actin-binding protein b
- Myosin VIIAa
- Fascin.
- Epidermal growth factor receptor kinase substrate 8-like protein 2
Sequence:
MVVERTLLAARQGDVQTLKVQFAEKVLNGDVKDVLGATPVHHAARAGKLTCLRYLVDEAGLPANSLARNGASPAHDAAATGNLTCLQWLVTHGGCRAADKDSSGATVLHLASRFSHHEIIDWLLKSEEGDPTVATDTGALPVHYAAAKGDLPSLRLLLEHSPQVVNFQTKNGATPLYLACQEGHLEVVQYLVKDCGAEPSIRANDGMTPLHAAAQMGHNTVIVWLMSFTEISLSDRDNDGATAMHFAASRGHAKVLSWLLLHGGEIMTDSWGGTPLHDAAENGELECCQILVVNGVDLGIRDQDGFSAADLAEYNGHQQCAKYLRTVENMSVEHRVLSRDASADLEYKQPDSGLSSPNATLPNPAPPAGHFDICSPSSSLSNYDSANSSQSSTGEKRSGSPPSRVPTGGTDSAITDMQTYMDMLNPDEACGSHNAKEAAHLPPPPTFPPPPPPSNPSHIPPPPPAYPAPNPPEEEEVSAEYLKVKRNLRRVDNDVVKKELVIFRQQLNPGENHERLRRVDSNRKSRSFSKQPSTGDYYKTLGSDTTDQQPSRAMAPNEEGSALLEEAADTAPAPENGTGTTEDLPLPPPPPPPPASTFIPAPPPPPPLPSELPPPPPPSTTTPAAAQRRMSSSSNSNKSFNMMSPTGDNSELLAEIKAGKSLKPTPHSKGYTTVFSNSGTPGNNGESPSSPPEPLPKPNDTQSAKPESPPPACPPTPPNPTASRSSPQNLSTSQSSDQLTAAVNGNTSVVQNKTSVVDVESLVPTHDEQGRAIPEWKRQVMVRKLQVKMQEEEENKRKAEEEAARLASLPAWRRDIMKKKLEEEKKDEEQRRMEKESEEKSELERLRTLGYDETKLAPWQKQIILKKGDIAKQ
Protein: Subtilisin-like protease SBT3.6 (EC 3.4.21.-) (Subtilase subfamily 3 member 6) (AtSBT3.6) (Q8L7I2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Secreted {ECO:0000250|UniProtKB:Q84WS0}.
Interaction partners:
Sequence:
MMNYRTSIYVVLSLVIFLNVQRSFVAESSAKRKVHIVYLGEKQHDDPEFVTESHHRMLWSLLGSKEDANDSMVYSYRHGFSGFAAKLTESQAKKIADLPDVVHVIPDSFYKLATTRTWDYLGLSAANPKSLLHETNMGEQIIIGVIDTGVWPESEVFNDSGFGPVPSHWKGGCETGENFNSSNCNKKLIGAKYFINGFLAENESFNSTNSLDFISPRDLDGHGTHVSTIAGGSFVPNISYKGLAGGTVRGGAPRAHIAMYKACWYLDDDDTTTCSSADILKAMDEAMHDGVDVLSISLGSSVPLYGETDIRDGITTGAFHAVLKGITVVCSGGNSGPDSLTVTNTAPWIITVAATTLDRSFATPLTLGNNKVILGQAMYTGPGLGFTSLVYPENPGNSNESFSGTCEELLFNSNRTMEGKVVLCFTTSPYGGAVLSAARYVKRAGGLGVIIARHPGYAIQPCLDDFPCVAVDWELGTDILLYTRSSGSPVVKIQPSKTLVGQPVGTKVATFSSRGPNSIAPAILKPDIAAPGVSILAATTNTTFSDQGFIMLSGTSMAAPAISGVAALLKALHRDWSPAAIRSAIVTTAWKTDPFGEQIFAEGSPPKLADPFDYGGGLVNPEKSANPGLVYDMGLEDYVLYMCSVGYNETSISQLIGKTTVCSNPKPSVLDFNLPSITIPNLKDEVTITRTVTNVGPLNSVYRVTVEPPLGFQVTVTPETLVFNSTTKKVYFKVKVSTTHKTNTGYYFGSLTWSDSLHNVTIPLSVRTQILQNYYDEN
Protein: Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2) (Q5U1Y2)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Neutrophil cytosolic factor 1
- NADPH oxidase 2
- Cytochrome b-245 light chain
- Neutrophil cytosol factor 4
- Proto-oncogene vav
- Dedicator of cytokinesis 2
- Serine/threonine-protein kinase PAK 1
- Plexin-B1
- TIAM Rac1 associated GEF 1
- Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKDIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRPCSLL
Protein: Chaperone modulatory protein CbpM (P63264)
Organism: Escherichia coli (strain K12)
Function: Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ.
Interaction partners:
- Curved DNA-binding protein
- Chaperone protein DnaJ
- Putative acyl-CoA dehydrogenase AidB
Sequence:
MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWVFDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP
Protein: Eukaryotic translation initiation factor 4E, putative (Q387Q8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Eukaryotic translation initiation factor 4E, putative
- Probable eukaryotic initiation factor 4A
- Polyadenylate-binding protein
- MIF4G domain-containing protein
- MIF4G domain-containing protein
- MIF4G domain-containing protein
- MIF4G domain-containing protein
- MIF4G domain-containing protein
- Polyadenylate-binding protein
- Elongation initiation factor 2 alpha subunit, putative
Sequence:
MQTLLRPRPGEPTLFGPPTNQCTQLWGVWEMWCVLPDGHEAATATPNVRGSGAKKGGMSKTKVKKATWLDQVRSIGLFDSAEGFWGIITCTLNPSQLPPGFNYYLFRRNIAPMWEHEANRRGGRWVMRFRVSQHDDSPATALDGAVAAAAEGQLPVDRAWEALCVAMIGEQLPGDETEICGAVVRRAERRRDWKLSLWTRTAADRCTQERIGFFVKDLLHLEDGSLQYFSHRELMQASEKGNWDVPPLYQL
Protein: Inner kinetochore subunit MCM21 (CENP-O homolog) (Constitutive centromere-associated network protein MCM21) (Minichromosome maintenance protein 21) (Q6CVQ9)
Organism: Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
Function: Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis (By similarity). Component of the inner kinetochore COMA subcomplex, which connects centromere-associated proteins and the outer kinetochore. COMA interacts with other inner kinetochore proteins to form the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q06675}. Chromosome, centromere, kinetochore {ECO:0000250|UniProtKB:Q06675}.
Interaction partners:
- Inner kinetochore subunit OKP1
- Inner kinetochore subunit AME1
- Inner kinetochore subunit CTF19
- Histone H3-like centromeric protein CSE4
- KLLA0D11770p
- KLLA0E05347p
- KLLA0B04070p
- Probable kinetochore protein SPC24
- KLLA0F22990p
- Probable kinetochore protein SPC25
Sequence:
MEETEAVQQDIEALEREIQTIKIQIANAHSGASKDEVKIPDAYKQFLSENINFSNLMRKDENTTLSINLSPRKPGTTTGQIQGIDSSIRSNFGVSSGHNEVAGFKSITDFVQWENSVRLIGVSLFPVNYDNIEFMGIRLELFDELSLKYDPPFYVILKPSVKRLGIWELFKHNLPKYINIHQHWQLITKDTDTSDSNIMKFANLCYKDLLKVHSRVQFFRKLEGNYVNDKQYSLLHIDNMGLNVSFRLGADIIKIKVDDGDDEIIDCTFNGEKNISLLGSIYGITNRFQSIIM
Protein: Small G protein signaling modulator 3 (Merlin-associated protein) (RUN and TBC1 domain-containing protein 3) (Rab-GTPase-activating protein-like protein) (RabGAPLP) (Q96HU1)
Organism: Homo sapiens (Human)
Function: May play a cooperative role in NF2-mediated growth suppression of cells.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15849434}.
Interaction partners:
- Ras-related protein Rab-5A
- Small G protein signaling modulator 1
- Small G protein signaling modulator 2
- Ras-related protein Rab-4A
- Ras-related protein Rap-1b
- Ras-related protein Rab-11A
- Ras-related protein Rab-3A
- Ras-related protein Rab-8A
- Ras-related protein Rap-2a
Sequence:
MSGSHTPACGPFSALTPSIWPQEILAKYTQKEESAEQPEFYYDEFGFRVYKEEGDEPGSSLLANSPLMEDAPQRLRWQAHLEFTHNHDVGDLTWDKIAVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAACLLLFLEEEDAFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIPSQMEDAELLLGVAMRLAGSLTDVAVETQRRKHLAYLIADQGQLLGAGTLTNLSQVVRRRTQRRKSTITALLFGEDDLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQRDHENYVACSRSHRRRAKALLDFERHDDDELGFRKNDIITIVSQKDEHCWVGELNGLRGWFPAKFVEVLDERSKEYSIAGDDSVTEGVTDLVRGTLCPALKALFEHGLKKPSLLGGACHPWLFIEEAAGREVERDFASVYSRLVLCKTFRLDEDGKVLTPEELLYRAVQSVNVTHDAVHAQMDVKLRSLICVGLNEQVLHLWLEVLCSSLPTVEKWYQPWSFLRSPGWVQIKCELRVLCCFAFSLSQDWELPAKREAQQPLKEGVRDMLVKHHLFSWDVDG
Protein: BHLH transcription factor (Hairy-related 12) (Q6TA36)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Transcription factor atoh7
- Neurogenic differentiation factor 1
- Neurogenin-1
- Neurogenic locus notch homolog protein 1
- Neurog3 protein
- Achaete-scute homolog 1a
- Atonal bHLH transcription factor 1a
- Heart- and neural crest derivatives-expressed protein 2
- Pancreas transcription factor 1 subunit alpha
Sequence:
MAPHSATLASFDHLHFSDKEKIKLRKPIVEKMRRDRINTCIDQLKSLLEKEFHSHDPSTKLEKADILEMTVSFLKQQIKQQQQIPQRDFNEGYSHCWRESVHFLSLHSNAGELQHLHSGPKTNSTMGSTPATACSKLNTAALQHPDSVRAVWRPW
Protein: Gibberellic acid receptor-b (A5Z1M8)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Interaction partners:
Sequence:
MAGSNEVNLNESKRVVPLNTWVLISNFKLSYNLQRRPDGTFNRDLSEFLDRRVPANINPVDGVFSFDHVDGATGLLNRVYQPSPKNEAQWGIVDLEKPLSTTEVVPVIVFFHGGSFTHSSANSAIYDTFCRRLVNICKAVVVSVNYRRSPEHRYPCAYDDGWAALKWVKSRTWLQSGKDSKVHVYLAGDSSGGNIAHHVAVRAAEADVEVLGNILLHPMFGGQMRTESEKRLDGKYFVTLHDRDWYWRAYLPEGEDRDHPACNPFGPRGRTLEGLKFPKSLVVVAGLDLIQDWQLAYVEGLKKSGQEVKLLFLEKATIGFYFLPNNDHFYRLMEEMNNFVHSNC
Protein: Intestine-specific homeobox (A1A546)
Organism: Mus musculus (Mouse)
Function: Transcription factor that regulates gene expression in intestine. May participate in vitamin A metabolism most likely by regulating BCO1 expression in the intestine.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Interaction partners:
- Beta,beta-carotene 15,15'-dioxygenase
- Scavenger receptor class B member 1
Sequence:
MAGPTIHRDMEKSSGYCEAPENLGLSFSIEAILKKPTERRSLPRPQSICKEDSRQTTIPGSKLERPPQDQPQEEKKNKRRVRTTFTTEQLQELEKLFHFTHYPDIHVRSQLASRINLPEARVQIWFQNQRAKWRKQEKSGNLSAPQQPGEAGLALPSNMDVSGPVLTPTAMTTLVPPTECCLLSQTQLPSSWFPTQIPLVPWHPWDLQPLPGPLTQHPCVPTFMFPPLHPKWGSICATST
Protein: Serine/threonine kinase SAD-1 (EC 2.7.11.1) (Synapses of Amphids Defective) (Q19469)
Organism: Caenorhabditis elegans
Function: Regulates both neuronal polarity and synaptic organization when bound to strd-1. Kinase activity is required for the establishment, but not the maintenance, of both processes. Binding to nab-1 is essential for role in restricting axonal fate during neuronal polarization but is not required for regulating synapse morphology.
Subcellular location: Synapse {ECO:0000269|PubMed:20023164}. Note=Synapse localization is regulated by strd-1. Co-localizes with strd-1 in synapses. {ECO:0000269|PubMed:20023164}.
Interaction partners:
- Nuclear anchorage protein 1
- Nuclear migration and anchoring protein unc-84
- Neurabin-1
- Nucleosome assembly protein 1-like 1
- Rho GTPase-activating protein syd-1
- Liprin-alpha
- Ras-related protein Rab-3
- Protein arginine N-methyltransferase 5
- RGS domain-containing protein
- Regulator of G-protein signaling 7
Sequence:
MFEALKEVLGEINSKLAAVNNELSSKIMSENIVSTRPVAQAQYCGPYKLEKTLGKGQTGLVKTGTHCITGRKVAIKIVNKEKLSESVLQKVEREIAIMKLIEHPHVLHLYDVYENKKYLYLLLEHVSGGELFDYLVRKGRLMSKEARKFFRQIISALDFCHAHNICHRDLKPENLLLDERNNIKVADFGMASLQVEGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPFDDDNLRNLLEKVKRGVFHIPHFVPADVQSLLRAMIEVDPGKRYSLADVFKHPWVSGTTKADPELELPMSQVVQTHVIPGEDSIDPDVLRHMNCLGCFKDKQKLINELLSPKHNTEKMVYFLLLDRKRRRPAQEDDTEIVLRGAAQNNDPPKKRTDSSRTSRYPMGSIADGSPINPRKTYGRNQKSGRHSSLGGSPTESPRSSTRDLFGSSSSGSYSARAGEDRDRGRSASRSTNSYHYYTQPVDPQTLAEAARHVRDAQERRESRDSGRGSSRKESKDRSDKSASSSSCKNDASSTSSVPHKYSPPSVMSESVVVSSSTMNSTNSSTNSLIAGNSQTSIGSTSGPWRSKLNNIKNSFLGTPRFHRRKMSNGTAESDSEDSQMIDTTDLVKKSWFGSLASSMSVERDDTHCVPVQGKTLNSIKAELIRAFLQIHELSHSVVGQNCFRVEYKRGPTVGGSVFSRGIKMNVDIIPSPQQVVIAGETPTYVVQFVLLAGPVRRFKRLVEHLSAILQNSTQQRADRQQQAALMVRPRRLSDSSVGSACSDSESNASSINMIARHSDKTETTSATSSDPYGPSPSMRSVGSGTANSYKSPTPHRRNTTAVTASSSSASNRYGPSSSSSGSYSNNADYSYHPEYSQRSNGSSAPKNQYSPGSQRSFAFSMFNKADKV
Protein: Homeobox protein BarH-like 2 (O08686)
Organism: Mus musculus (Mouse)
Function: Transcription factor. Binds optimally to the DNA consensus sequence 5'-YYTAATGRTTTTY-3'. May control the expression of neural adhesion molecules such as L1 or Ng-CAM during embryonic development of both the central and peripherical nervous system. May be involved in controlling adhesive processes in keratinizing epithelia.
Subcellular location: Nucleus.
Interaction partners:
Sequence:
MHCHAELRLSSPGQLKAARRRYKTFMIDEILSKETCDYFEKLSLYSVCPSLVVRPKPLHSCTGSPSLRAYPLLSVITRQPTVISHLVPTGSGLTPVLTRHPVAAAEAAAAAAETPGGEALASSESETEQPTPRQKKPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKGGQEAPTKPKGRPKKNSIPTSEEIEAEEKMNSQAQSQELLESSERQEEPCDTQEPKACLVPLEVAEPIHQPQELSEASSEPPPLS