wanglab/gogpt-training-data huggingface dataset:
Protein: Cyclin-dependent kinase 5 activator (Q8N619)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004342}; Lipid-anchor {ECO:0000256|ARBA:ARBA00004342}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004342}. Cell projection, neuron projection {ECO:0000256|ARBA:ARBA00004487}. Cytoplasm, perinuclear region {ECO:0000256|ARBA:ARBA00004556}. Nucleus {ECO:0000256|ARBA:ARBA00004123}. Perikaryon {ECO:0000256|ARBA:ARBA00004484}.
Interaction partners:
Sequence:
MGTVLSLSPSYRKATLFEDGAATVGHYTAVQNSKNAKDKNLKRHSIISVLPWKRIVAVSAKKKNSKKVQPNSSYQNNITHLNNENLKKSLSCANLSTFAQPPPAQPPAPPASQLSGSQTGGSSSVKKAPHPAVTSAGTPKRVIVQASTSELLRCLGEFLCRRCYRLKHLSPTDPVLWLRSVDRSLLLQGWQDKGFITPANVVFLYMLCRDVISSEVGSDHELQAVLLTCLYLSYSYMGNEISYPLKPFLVESCKEAFWDRCLSVINLMSSKMLQINADPHYFTQVFSDLKNESGQEDKKRLLLGLDR
Protein: Calmodulin-like protein 9 (AtCaM-9) (Q9S744)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Potential calcium sensor.
Interaction partners:
- Two-component response regulator-like APRR2
- Probable calcium-binding protein CML47
- T14N5.3 protein)
- Probable calcium-binding protein CML46
- At1g17330
- At1g73440
- Probable calcium-binding protein CML48
Sequence:
MADAFTDEQIQEFYEAFCLIDKDSDGFITKEKLTKVMKSMGKNPKAEQLQQMMSDVDIFGNGGITFDDFLYIMAQNTSQESASDELIEVFRVFDRDGDGLISQLELGEGMKDMGMKITAEEAEHMVREADLDGDGFLSFHEFSKMMIAASY
Protein: Protein YIF1 (Q9VBC5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|RuleBase:RU368073}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU368073}. Golgi apparatus membrane {ECO:0000256|RuleBase:RU368073}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU368073}.
Interaction partners:
Sequence:
MNYNPNPGMRNPSAAGRPRPPKRVSDVNAMGPSAPMMGGGATFMAPPTGPGILDPNMYGAPAPAPVNSYGFDPNLGQPSQHIQQPPQQQPGYGYGAPPPQQAAGPPTYGIGAPQPVAPPTGQYPQFAMFQQPIVQDMAMQYGQKLADQGKQIMENQFEKWVPVAKLKYYFAVDNAYVGRKLRLLFFPYMHKDWSLRYDQEHPVQPRYDVNAPDLYLPTMGYITYVIVAGLLLGMQKRFSPEQLGIQASSAMAYSIFELVIYSLALYVMNVKTSLKTLDLLAFTGYKYVNIVVCLMVSTLFFKSGYYIALAYTSFSFGFFMLRTLRTKLLQDNSPAAPSGAINYDPYGNPQQFDYSGGKKRKLYFLFMIVAGQALFAFLLSKHLYLPEAEVLTVPKTF
Protein: Homeobox protein Hox-C13a (Q6JIY5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
Interaction partners:
Sequence:
MTTSQVLHPRWADTLMYVYEKSPNENNQNKSQIMEGLSGNCPATHCRELISHPALGRHSGTIATHQGSVYSDISSPETGRQCPAPQTSSSASLSYGYPFGNPYYGCRLSHSHNVNLQQKPCSYHPAEKYAETSSALPTEELSSRAKEFAFYPSLASSYQAVPGYLDMSVVPSISVHPEPRHDALIPMEGYQHWALSNGWDGQVYCSKEQTQSSHLWKSPFPDVVPLQPEVSSYRRGRKKRVPYTKIQLKELEKEYAASKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKFVSKSKTNNHMHT
Protein: Transcription factor WRKY45-1 (OsWRKY45-1) (OsWRKY45) (WRKY transcription factor 45-2) (Q5W6D6)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcriptional activator involved in defense responses against pathogens. Acts as positive regulator of defense responses against the rice blast fungus Magnaporthe oryzae. Acts through W-boxes, which are cis-elements that are enriched in the promoters of several defense-related genes. Plays an important role in the benzothiadiazole-induced disease resistance by mediating salicylic acid (SA) defense signaling pathway, independently of the disease resistance gene NPR1/NH1. Acts as negative regulator of defense responses against the bacterial blight Xanthomonas oryzae pv oryzae (Xoo) and the bacterial streak Xanthomonas oryzae pv oryzicola (Xoc). Acts downstream of abscisic acid (ABA) signaling in response to the rice blast fungus. ABA is a negative regulator of defense responses that interacts antagonistically with salicylic acid (SA) signaling pathway. Acts as negative regulator of ABA signaling that suppresses growth of seedlings. Does not seem to be involved in the regulation of salt stress response. Acts as negative regulator of cold stress response. Acts as negative regulator of drought stress response.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00223}.
Interaction partners:
Sequence:
MTSSMSPAPAPAYAQVMEDMEKGKELAAQLQGLLRDSPEAGRFVDQILHTFSRAMRALDKAAVSAAGGEGSEVQSEVTCGGGASAGGKRKAPAADRKANCRRRTQQSSGNSVVVKNLDDGQAWRKYGQKEIQNSKHPKAYFRCTHKYDQLCTAQRQVQRCDDDPASYRVTYIGEHTCRDPATAPIIAAHVIHQVAAGDNDDGCGGLQAGSRLISFVAAPAAPVDAAAAPTTSTITTVTAPGPLLQPLKVEGGVGSSDQEEVLSSLTPGSSAARGGGGGGGVAGPFGPDQGDVTSSLHWSYDAVAGMEFFKNDEVVFDLDDIMGLSF
Protein: MOB kinase activator 1A (Mob1 alpha) (Mob1A) (Mob1 homolog 1B) (Mps one binder kinase activator-like 1B) (Q9H8S9)
Organism: Homo sapiens (Human)
Function: Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L. Acts cooperatively with STK3/MST2 to activate STK38.
Interaction partners:
- Serine/threonine-protein kinase 38-like
- Serine/threonine-protein kinase 4
- Serine/threonine-protein kinase LATS1
- Serine/threonine-protein kinase 3
- Serine/threonine-protein kinase LATS2
- MOB kinase activator 1B
- Serine/threonine-protein kinase 38
- Protein salvador homolog 1
- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
Sequence:
MSFLFSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
Protein: FI01423p (Glutathione S transferase E3 (EC 2.5.1.18)) (A1ZB68)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Glutathione S transferase E7
- Glutathione S-transferase D2
- Bifunctional glutamate/proline--tRNA ligase
- Glutathione S transferase T1
- Glutathione S transferase E9
- Glutathione S transferase O3
- Glutathione S transferase E6
- Glutathione S transferase D10, isoform A
- NADP-retinol dehydrogenase
- Glutathione S-transferase D4
Sequence:
MGKLTLYGIDGSPPVRSVLLTLRALNLDFDYKIVNLMEKEHLKPEFLKINPLHTVPALDDNGFYLADSHAINSYLVSKYGRNDSLYPKDLKKRAIVDQRLHYDSSVVTSTGRAITFPLFWENKTEIPQARIDALEGVYKSLNLFLENGNYLAGDNLTIADFHVIAGLTGFFVFLPVDATKYPELAAWIKRIKELPYYEEANGSRAAQIIEFIKSKKFTIV
Protein: Phospholipase A2 (bvPLA2) (EC 3.1.1.4) (Allergen Api m I) (Phosphatidylcholine 2-acylhydrolase) (allergen Api m 1) (P00630)
Organism: Apis mellifera (Honeybee)
Function: PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
Subcellular location: Secreted.
Interaction partners:
- Apamin
- Melittin
- Hyaluronidase
- Uncharacterized protein.
- Hyaluronidase.
- Phospholipase A
- Uncharacterized protein.
- Uncharacterized protein
- PA2c domain-containing protein.
- PA2c domain-containing protein.
Sequence:
MQVVLGSLFLLLLSTSHGWQIRDRIGDNELEERIIYPGTLWCGHGNKSSGPNELGRFKHTDACCRTHDMCPDVMSAGESKHGLTNTASHTRLSCDCDDKFYDCLKNSADTISSYFVGKMYFNLIDTKCYKLEHPVTGCGERTEGRCLHYTVDKSKPKVYQWFDLRKY
Protein: Uncharacterized protein (Q55GQ4)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Uncharacterized protein DDB_G0274171
- PHD zinc finger-containing protein
Sequence:
MRNLENYLFSNKSFNSQKEGYKNRISVNLFIRPVESSSSSSSTSSRSPSVVFKSYINDHISNNERYTSIINHIESKGHIIEQLHPYSSLPSSPSNDIHYATIGSDKLLSNLPLLKDHIINKIPLIFLDVNNNENKKEFCEMVNNVCTMDNDHHNILAYIPTTKNGLEYHKVFNWINETNSNIDSQSSDIGSGSSSRSYVATIINSTIEFGENENIETNENHNFNNQFKPITNLLLSKLMVNKDESNNDDNGYVNLNENNSPSSSLIPPTNSSIPFKYFESTFANSFIAYINPSLTSKVTQQTFSYSVTNHIYLYKDEPNNCIYSIIYQNSFILPDTHLGVNDPSKAIGSFITSFGTSNKPTIGGEQSSPSSSSSPLNSNLFNLEATSPHTIDQTHTVTNEVTTDISIGINLDVNPEGPGGGVSFGESWSSSSSETQTISDYGIEEKSNPVTMESAWVYHQQMPFDVYYLGFNNFGEWYKSAFTTNGHVAQPPPLSTSTLQTSTSWKWRLDNSLIDKSNNQLIVNIDLTLDLSYCLVSCPGFYDHHHKLFYCHSTFSNFQTFDFNAFK
Protein: SPT3, SAGA and STAGA complex component (Q8BVY4)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Transformation/transcription domain-associated protein
- Transcription initiation factor TFIID subunit 12
- Transcriptional adapter 3
- Transcription initiation factor TFIID subunit 6
- Transcription initiation factor TFIID subunit 10
- SAGA-associated factor 29
- Transcription factor SPT20 homolog
- Transcriptional adapter 2-alpha
- Transcriptional adapter 1
- Transcriptional adapter
Sequence:
MNNAAASPMSTTTSSSGRNAGKTISFAAELQSMMFSLGDARRPLHETAVLVEDVVHTQLINLLQQAAEVSQLRGARVISAEDLLFLMRKDKKKLRRLLKYMFIRDYKSKIIKGIDEDDLLEEKLSGSSGTNKRQKIAQDLINSIDQTGELLAMFEDNELDDVKQERMERAERQTRTMDSAQYAEFCESRQLSFSKKASKFRDWLDCSSMEIKPNVIAMEILAYLAYETVAQLVDLALLVRQDMVSKAGDPFSHAISATFIQYHNSAEGSSCLKSSPDSPENTPPPTPTAPSSGSQHSGRAASGSLGNGNTGQDTAKTKQRKRKKSTAACGVEAHSDAIQPCHIREAIRRYGHKIGPLSPFTSAYRRSGMAFLAC
Protein: Serine/threonine-protein phosphatase (EC 3.1.3.16) (Q6NSN6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Protein phosphatase 1 regulatory subunit 12C
- Protein phosphatase 1 regulatory subunit 14A
- Protein phosphatase 1 regulatory subunit 12A
- Retinoblastoma 1.
- Protein phosphatase 1, regulatory
- Serine/threonine-protein phosphatase
- Serine/threonine-protein phosphatase
- WD repeat-containing protein 82
- Eukaryotic translation initiation factor 2 subunit 1
- Eukaryotic translation initiation factor 2 subunit 1
Sequence:
MAEPDKLNIDSIIQRLLEVKGSRPGKNVQLTESEIRGLCLKSREIFLSQPILLELEAPLKICGDVHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKVKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPVAAIVDEKIFCCHGGLSPDLQSMEQVRRVMRPTDVPDQGLLCDLLWADPDKDVLGWGENDRGVSFTFGADVVAKFLHKHDMDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKKLYYGGGGGMGSGRPVTPPRNSAKGGKAKK
Protein: Tafazzin family protein (A0A8I6ABG2)
Organism: Rattus norvegicus (Rat)
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004137}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004137}; Intermembrane side {ECO:0000256|ARBA:ARBA00004137}. Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00024323}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00024323}; Intermembrane side {ECO:0000256|ARBA:ARBA00024323}.
Interaction partners:
Sequence:
MPLHVKWPFPAVPRLTWTLASSVVMGLVGTYSCFWTKYMNHLTVYNKEVLYELIENRGPATPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVPVCRGDGVYQKGMDFILEKLNHGDWVHIFPEGKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSTLPVLERLRAENKSAVSFLQGFPSCPSPFQSLRLPGYPSYGP
Protein: Uncharacterized Rab geranylgeranyltransferase C15C4.03 (O60112)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- GTP-binding protein ypt1
- GTP-binding protein ryh1
- Zinc finger protein sfp1
- GTP-binding protein ypt2
- GTP-binding protein ypt3
- UBA domain-containing protein 7
- Geranylgeranyl transferase type-2 subunit beta
- GTP-binding protein ypt5
- Ypt/Rab-type GTPase ypt71
- Ypt/Rab-type GTPase ypt7
Sequence:
MDDPNSYDVIIVGTNLRNSILSAALSWANQRVLHIDENSFYGEIDGSLTLRDLEQINEKIKKVDSSQILNDNGSHKSPLKRFEVQFLNKDLIPKNKGSVIQFHPQEIFASSELVKLLSETKIYKYLLLKPARSFRLLTSNEEWIKVPESRADIFNNKNLSLASKRIVMRFMKFVSNIADEQNQNLVKEWESKPFYKFLEEVFQLSGAIEESIIYGLCQSLSKDIPTKDALDTVLKYFHSFGMYGDYSYLLAMYGTGSELCQGFCRSSAVMGGTFMLGQAIDKIDESKIVLKDGSTLSAKKIVSSVDEGKLPHQQIQQRYLLVKGDCQQLFQEDGFFAALDASLIHFSPFSISENFGNSVQAKLYGSGSGDCPEGYCIWYLKTLNDSPCNEVFNLATKKLCSFSGCDDLEIIVQVDETLNQLRHIDYDDTLHSAKSLFYEILGQNNTFLQREGLFDEDDE
Protein: Protein M2-2 (Q6WB96)
Organism: Human metapneumovirus (strain CAN97-83) (HMPV)
Function: Mediates the regulatory switch from transcription to RNA replication (By similarity). Acts late in infection by inhibiting viral transcription and up-regulating RNA replication (By similarity). Plays a major role in antagonizing the type I IFN-mediated antiviral response. Interacts with host MAVS and prevents the interaction with its upstream partner RIGI in the signaling pathway leading to interferon production.
Subcellular location: Host cytoplasm {ECO:0000250|UniProtKB:P88812}.
Interaction partners:
Sequence:
MTLHMPCKTVKALIKCSEHGPVFITIEVDEMIWTQKELKEALSDGIVKSHTNIYNCYLENIEIIYVKAYLS
Protein: LOC799377 protein (A8WGT5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
RDTLAEEIMRNMLSLLAVLTVYLAVWGGITVDAQVGSVLRNSIRHLPAASSPSDAVSASPRVTGTVDSDAPPSPHCSADSECSIGEFCNGSRGVCLSCRKRRKRCARDGMCCAGNRCINGVCQLADAAAVGSADASPPGGNTDVSGVAVTRGQNFTHPRRTTVLSKPQQTQKGGEGETCLRSSDCLEGLCCARHFWSRICKPVLTEGQVCTRHRRKGAHGLEIFQRCDCGSGLTCRGQREKPGAESRNLHTCQPR
Protein: Guanidinobutyrase (EC 3.5.3.7) (Q9I3S3)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Catalyzes specifically the hydrolysis of 4-guanidinobutanoate to 4-aminobutanoate and urea. Has no activity against arginine, agmatine, 3-guanidinopropionate and guanidinoacetate.
Interaction partners:
- Probable sodium:solute symport protein
- SnoaL-like domain-containing protein
- Aliphatic amidase
- Probable transporter
- Probable aldehyde dehydrogenase
- Probable aldehyde dehydrogenase
- aldehyde dehydrogenase
- Bifunctional protein PutA
- Amidase domain-containing protein
- Probable amidase
Sequence:
MDKNLHQPLGGNEMPRFGGIATMMRLPHVQSPAELDALDAAFVGVPLDIGTSLRSGTRFGPREIRAESVMIRPYNMATGAAPFDSLNVADIGDVAINTFNLLEAVRIIEQEYDRILGHGILPLTLGGDHTITLPILRAIKKKHGKVGLVHVDAHADVNDHMFGEKIAHGTTFRRAVEEDLLDCDRVVQIGLRAQGYTAEDFNWSRKQGFRVVQAEECWHKSLEPLMAEVREKVGGGPVYLSFDIDGIDPAWAPGTGTPEIGGLTTIQAMEIIRGCQGLDLIGCDLVEVSPPYDTTGNTSLLGANLLYEMLCVLPGVVRR
Protein: Chlorophyll a-b binding protein AB80, chloroplastic (LHCII type I CAB-AB80) (LHCP) (P07371)
Organism: Pisum sativum (Garden pea) (Lathyrus oleraceus)
Function: The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
Subcellular location: Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MAASSSSSMALSSPTLAGKQLKLNPSSQELGAARFTMRKSATTKKVASSGSPWYGPDRVKYLGPFSGESPSYLTGEFPGDYGWDTAGLSADPETFSKNRELEVIHSRWAMLGALGCVFPELLSRNGVKFGEAVWFKAGSQIFSEGGLDYLGNPSLVHAQSILAIWATQVILMGAVEGYRIAGGPLGEVVDPLYPGGSFDPLGLADDPEAFAELKVKELKNGRLAMFSMFGFFVQAIVTGKGPLENLADHLADPVNNNAWSYATNFVPGK
Protein: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform (PP2A B subunit isoform B'-alpha) (PP2A B subunit isoform B56-alpha) (PP2A B subunit isoform PR61-alpha) (PR61alpha) (PP2A B subunit isoform R5-alpha) (Q15172)
Organism: Homo sapiens (Human)
Function: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:8703017}. Nucleus {ECO:0000269|PubMed:8703017}. Chromosome, centromere {ECO:0000269|PubMed:16541025}. Note=From mitotic prophase to metaphase, localizes at the inner centromere between a pair of sister kinetochores. Decreased expression at the onset of anaphase. {ECO:0000269|PubMed:16541025}.
Interaction partners:
- Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
- Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
- Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
- Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
- Mitotic checkpoint serine/threonine-protein kinase BUB1 beta
- Shugoshin 1
- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
- Apoptosis regulator Bcl-2
Sequence:
MSSSSPPAGAASAAISASEKVDGFTRKSVRKAQRQKRSQGSSQFRSQGSQAELHPLPQLKDATSNEQQELFCQKLQQCCILFDFMDSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAYSDIVKMISANIFRTLPPSDNPDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQNSAYNMHSILSNTSAE
Protein: Netrin-G2 (Laminet-2) (Q96CW9)
Organism: Homo sapiens (Human)
Function: Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites.
Subcellular location: Cell membrane {ECO:0000269|PubMed:21946559, ECO:0000269|PubMed:31668703}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:21946559}; Extracellular side {ECO:0000269|PubMed:21946559, ECO:0000269|PubMed:31668703}.
Interaction partners:
- Leucine-rich repeat-containing protein 4
- Leucine-rich repeat-containing protein 4C
- Leucine-rich repeat-containing protein 4B
- Cyclin-dependent kinase-like 5
Sequence:
MLHLLALFLHCLPLASGDYDICKSWVTTDEGPTWEFYACQPKVMRLKDYVKVKVEPSGITCGDPPERFCSHENPYLCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPSPLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGMSARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRLESAKGLKEFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANLCSMREGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCNETGFCECREGAAGPKCDDCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCACPRGYTGVRCEQPRCDPADDDGGLDCDRAPGAAPRPATLLGCLLLLGLAARLGR
Protein: Activator of photopigment and puc expression (P74295)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Interaction partners:
- PatA subfamily
- Riboflavin synthase
- Phytochrome-like protein cph2
- Circadian input-output histidine kinase CikA
Sequence:
MSLYRLIYSSQGIPNLQPQDLKDILESSQRNNPANGITGLLCYSKPAFLQVLEGECEQVNETYHRIVQDERHHSPQIIECMPIRRRNFEVWSMQAITVNDLSTEQVKTLVLKYSGFTTLRPSAMDPEQCLNFLLDIAKIYELSDNFFLDL
Protein: Short-chain dehydrogenase/reductase SDRA (EC 1.1.-.-) (Protein INDOLE-3-BUTYRIC ACID RESPONSE 1) (Short-chain dehydrogenase/reductase A) (Q9S9W2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved with IBR3 and IBR10 in the peroxisomal beta-oxidation of indole-3-butyric acid (IBA) to form indole-3-acetic acid (IAA), a biologically active auxin. May be responsible for catalyzing the dehydrogenation step in the conversion of IBA. May be involved in the peroxisomal activation of 2,4-dichlorophenoxybutyric acid (2,4-DB), a precursor of active auxins that inhibit root growth.
Subcellular location: Peroxisome {ECO:0000269|PubMed:19043666, ECO:0000305|PubMed:17951448}.
Interaction partners:
- Enoyl-CoA hydratase 2, peroxisomal
- Enoyl-CoA delta isomerase 2, peroxisomal
- Probable acyl-CoA dehydrogenase IBR3
- 3-ketoacyl-CoA thiolase 2, peroxisomal
- Probable enoyl-CoA hydratase 1, peroxisomal
- Probable acyl-activating enzyme 18, peroxisomal
- Peroxisomal fatty acid beta-oxidation multifunctional protein AIM1
- ABC transporter G family member 36
- Small ribosomal subunit protein uS2y
Sequence:
MEKKLPRRLEGKVAIVTASTQGIGFGITERFGLEGASVVVSSRKQANVDEAVAKLKSKGIDAYGIVCHVSNAQHRRNLVEKTVQKYGKIDIVVCNAAANPSTDPILSSKEAVLDKLWEINVKSSILLLQDMAPHLEKGSSVIFITSIAGFSPQGAMAMYGVTKTALLGLTKALAAEMAPDTRVNAVAPGFVPTHFASFITGSSEVREGIEEKTLLNRLGTTGDMAAAAAFLASDDSSYITGETLVVAGGMPSRL
Protein: Mitogen-activated protein kinase kinase kinase kinase (EC 2.7.11.1) (A0A0B4LFV0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAAAHSHHNANMLSSDISRRNPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQIIQQEIIMMRDCRHPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGKMHRDIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKTALTKNPKKRPTAERLLQHPFVQCEMSLRVAKELLQKYQSPNPQFYYYLDGDEESVAGVPQRIASKMTSRTNGVPAQNHTLKTGMTTNSTWNERSSSPETLPSDIATLPLNNDTKDPLGAECSCSSHNGGAAGGGGGGGVGVGAGGAAANGSSSSSGGATVGTTHHQHQQHHQHHHHPNHLHQHQSHQLPQQQQQQSHQAAQQEHHHHHPMTSSISSGLVTANANNISSSASLASMPGLSAYLGMRSHVVGHMGMGFGMGLGMSNLRTTSIDADDDELVAADVAMNNAAAAVPGNGSGAGNGSGSGCSASAAHYLRYSSNYRSAAAAQASQAAHPHVNSNSNSNNGHGHAPITSSISSSASSASFYNRLLLLDNSSGDAVVGGNGGGSSNISSSGGASSGTNGLLDKHELDALPQAATKSAGDGFSHSNSPTANSGAGATGSRDNDGPSSSNSSHLYQNLLRSSSGETPAGSSSAGNNCDYRHENNQNGLEDSPRRHSSMDQLIGLLENMGKSPRTRSLSDGGTQDDDEAEKEAQPDLLNNTPPVPPKRSHKRRHTPPRPISNGLPPTPKVHMGACFSKIFNGCPLRVHCTASWIHPETRDQHLLIGAEEGIYNLNMNELHDAAIDQLFPRRTTWLYVIKDVLMSLSGKSCQLYRHDLVALHSKQTVRFSLHMNKIPERLVPRKFALTTKVPDTKCCTQCCVTRNPYNGYKYLCGATPSGIFLMQWYDPLNKFMLLKQCEWPAISIQGGGHGCVQNGHTPVFEMIITPELEYPIVCTGVRKAMNGCLKLELINMNSASWFHSEDLEYDAMATMVPRRDLLKVVRVHQVEKDAILVCYGNLIQVVTLQGNPKQHKKMVSQLNFDFNVDSIVCLPDSVLAFHKHGMQGKSLRNGEVTQEIKDMSRTYRLLGSDKVVALESQLLRTGSLGSEEGHDLYILAGHEASY
Protein: Os04g0618600 protein (A0A0P0WF46)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEARRPTPTRRSRSAEFHNFSERRRRDRINEKLKALQELLPNCTKTDKVSMLDEAIDYLKSLQLQLQMLVMGKGMAPVVPPELQQYMHYITADPSQIPPIRPSEPRPFQITHATQQRQSNVESDFLSQMQNLHPSEPPQNFLRPPKLQLYTPEQQRRGLASSSGHNSGWITERNSSYNFLE
Protein: ALG-2 interacting protein X (Alix) (Dd-Alix) (DdAlix) (Q8T7K0)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Unknown. Required for development but not for cell death.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:15708561}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:15708561}. Endosome {ECO:0000269|PubMed:15708561}. Note=Colocalizes to large vesicle-like structures with chmp4. Colocalizes with vamp7A to endosomes but not to lysosomes.
Interaction partners:
- Charged multivesicular body protein 4
- ESCRT-I complex subunit tsg101
- Vacuolar protein sorting-associated protein 28
- Heat shock protein DnaJ family protein
- Charged multivesicular body protein 1
- Charged multivesicular body protein 6
Sequence:
MLSIERKRTEKVDFSKPLTKYIKEQFSKAESDQHETQIATLNGLREDVRNLQERTETSKEMVWKYYSILSSLELRFPISENNVRISFPWTDSYRQRKSTLYSIYFERASVLFNYGSIVSQIASSTNRSNIEGVKKACNQFQLAAGVFNKLREYASLHPECSTSADFSSESLQALVTIMLAQAQECIYEKASMDNLSDSILSKLAAQVAEYYDTFNQLLNSNSLKSIVDRNWNITATVKSYLYKAISLYCHAKGLEQVSQFGEQVSRLMIAVDNINQSKVNLAKTAPIELKEIVERYVISITRYCESAKKDNDTIYHDTIPPAHKLTPIEKKPLAKALPLPEINFVDPFNSLVPFSVKEDSAYYNDQKETLLRKELDNIEFHNQSAKASLLSMGLPGSIEALDVGVPVALKEKMNVVTNEQGVSNITRLLENIQQLSDEDSAICLSAGNLLKKEEDEDNLMRATYGAQWHRTPSYTLTANLTQDYAKYTSHLQHSTKSDSFIRKKFEDHKNSIQELENQTEIIALLPTNNLPSGKIAEIASLTVLMNDLDALMANRESIAEKLKNLCKKDDITLKLLSPQKDKSLIYAEEIQKYEPLQMSLNESFLKQQKLIEDIRKENEKFTNQKSKQGNQREEILQKYANAYKVYNELKANLDEGTQFYLNFQEILNKFLNRCKDFTTGRENEKIELKRQIEAGVNPHSPLTSPSPSLQSPVNNYPNQFSSPQYHTSPNQQQQQQQQYVPSSQPPPQYSYNPQPYQPPQQFGGPLPPPQSFSAPPPPQSFTAPPPYNSNNKHY