wanglab/gogpt-training-data huggingface dataset:
Protein: Senescence-associated protein 13 (Tropinone reductase homolog SAG13) (EC 1.1.1.-) (Q9ZW18)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Unspecific reductase providing both diastereomeric alcohols from the prochiral ketones. Active on cyclic monoterpenes and small flexible lipophilic carbonyls. No activity with tropinone, nitrogen-containing tropinone analogs, tropine or pseudotropine as substrate.
Interaction partners:
- Senescence-specific cysteine protease SAG12
- Protein SENESCENCE-ASSOCIATED GENE 21, mitochondrial
- NAC domain-containing protein 92
- Senescence associated gene 20
- At1g71190
- Tropinone reductase homolog At2g29310
- Blue copper protein
- Senescence-associated carboxylesterase 101
- Bidirectional sugar transporter SWEET15
- NAC transcription factor 29
Sequence:
MAKEGGLGENSRWSLGGMTALVTGGSKGIGEAVVEELAMLGAKVHTCARDETQLQERLREWQAKGFQVTTSVCDVSSRDQRVKLMETVSSLYQGKLNILVNNVGTSIFKPTTEYTAEDFSFVMATNLESAFHLSQLAHPLLKASGSGSIVLISSAAGVVHVNVGSIYGATKGAMNQLARNLACEWASDNIRTNSVCPWYITTPLSNDFFDEEFKKEAVRTTPMGRVGEANEVSPLVAFLCLPSASYITGQTICVDGGATVNGFSFKTMP
Protein: Glycoprotein endo-alpha-1,2-mannosidase (EC 3.2.1.130) (A7RDN7)
Organism: Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004323}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004323}.
Interaction partners:
Sequence:
MAKFRRKTCIILSLFILFIFSLMMGLKMLRPNTSAFGTPFGLDLLPELHPPNAPLENKVDFQKSDRINMETNTKDLKAAVETVQPPKASEVNLEELPPLNYFLHVFYYSWYGNPQFDGKYIHWNHPVLEHWDPRIAKNYPQGIHTPPDDIGSSFYPELGSYSSRDPSVIETHMRQMCSASIGVLALSCYPPDSNDENGEATDHLVPTILDKAHKYNLKVTFHVEPYSNRNDQNMYTNVKYIIDKYGSHPAFYRYKTRTGHSLPMFYIYDSYITKPNVWANLLTPSGSQSVRNSPYDGLFIALLVEEKHKNDILQSGFDGIYTYFATNGFTYGSSHQNWGNLKSFCDKNNLIFIPSVGPGYIDTSIRPWNTQNTRNRINGKYYEVGLSAALQTHPNLISITSFNEWHEGTQIEKAVPKRTTTTVYLDYRPHKPSYYLELTRKWPEKYSKERKTYALDQQLPTS
Protein: Zgc:158336 protein (A2RUX6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MASCSSRVCLGLYPLLLLFSSSSSSCAPGRSWAVQLQPDSLSSAGSPDLLAQAVAQDVGLRSHGQIGQLEGHYLLCQDPAQGEDWRWMEAALDRHPHVAWHSQENVLRRSKRSVHFNDPKFPSQWHLHNDMKRGMDINVTGVWERNITGAGVTVVVVDDGIQHNLADIQPNYSPEGSYDLNSNDPDPMPHPDGPSDNHHGTRCAGEIAAVSNNSFCAVGVAYGSRVAGIRVLDGPLTDSMEAIAFNKHYQVNDIYSCSWGPDDDGRTVDGPHPLGKAALQHGVIAGRKGFGSIFIVASGNGGQNQDNCNYDGYANSIYTVTIGAVDESGRKPSYAEECASMLAVTFSSGNTPLRSIVTSDWSLQSGTGCTSGHTGTSAAAPLAAGMVALMLQVRPCLSWRDVQHIITYTATQHDLQADWVTNGAGFHHSHKYGFGLLNAWRLVNAAKVWESVPFLVSYQSPVLRVNEVITTSTNLTQTWNVSESDLQRSGMQTLEHVSVTLSIQHPRRGNLQILLLCPSGISSLIGARRALDVDSAGLTDWTFSTVRCWGERAEGQYSLLIMDDAPLSSGILKSWKLTLYGSSLSHQQVTDRQRVVEEAMSGHYLSSSFSLPCPPGIDVPAEIVNPFTSSSLKSLLLLGCFALFWSLYYTLEVALTHWDWRGGCVRGRDGDAGYSRLSRDEAQTDPQQVEVLLETHSQDKVLLIADTHT
Protein: U-box domain-containing protein 39 (EC 2.3.2.27) (Plant U-box protein 39) (RING-type E3 ubiquitin transferase PUB39) (Q9STT1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Functions as an E3 ubiquitin ligase.
Interaction partners:
- RNI-like superfamily protein
- IQ domain-containing protein IQM5
Sequence:
MGDTGRHKWFSFHHHRSASATTMPQHNSPGETPTEFLCPITGFLMSDPVVVASGQTFERISVQVCRNLSFAPKLHDGTQPDLSTVIPNLAMKSTILSWCDRNKMEHPRPPDYAYVEGVVRTRMDSLPPGSGHRIAKSEILPPVAENSNSNSDYDSVMGAIRSRSRTSLSSTTSLPLHQTRPINHSTRIQSSFSTSDYSSFPPMSPEEEEIYNKLTSVDTIDHEQGLIQLRKTTRSNETTRISLCTDRILSLLRSLIVSRYNIVQTNAAASIVNLSLEKPNKLKIVRSGFVPLLIDVLKSGSTEAQEHVIGALFSLAVEEENKMVIGVLGAVEPLLHALRSSESERARQDAALALYHLSLIPNNRSRLVKAGAVPMMLSMIRSGESASRILLLLCNLAACSEGKGAMLDGNAVSILVGKLRESGGAESDAAARENCVGALLTLSVGNMRFRGLASEAGAEEILTEIVESESGSGRLKEKASKILQTLRGGGSEFGEGAEAREWNRMLEASGLSRSQFQQGGQKGGFAYSSQF
Protein: Probable plastid-lipid-associated protein 13, chloroplastic (Fibrillin-7b) (AtPGL30) (Q8S9M1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Plastid, chloroplast, plastoglobule {ECO:0000269|PubMed:16461379, ECO:0000269|PubMed:22274653}.
Interaction partners:
- Probable plastid-lipid-associated protein 10, chloroplastic
- Probable plastid-lipid-associated protein 8, chloroplastic
- Probable plastid-lipid-associated protein 3, chloroplastic
- Plastid-lipid-associated protein 6, chloroplastic
- Probable plastid-lipid-associated protein 1, chloroplastic
- Probable plastid-lipid-associated protein 2, chloroplastic
- Fibrillin-5, chloroplastic
- Protein ACTIVITY OF BC1 COMPLEX KINASE 7, chloroplastic
- Probable plastid-lipid-associated protein 11, chloroplastic
- Protein ACTIVITY OF BC1 COMPLEX KINASE 3, chloroplastic
Sequence:
MALIHGSVPGTSAVRLVFSTSASPSRFCLNVPVVKQGWKNSCRRRVLRAMVQETVQGSPLVYAREMERLSAKESLLLALKDAGGFEALVTGKTTNMQRIDVNERITSLERLNPTPRPTTSPCFEGRWNFEWFGSGSPGLLAARVIFERFPSTLANLSRMEILIKDANAKATANIKLLNSIESKIILSSKLTVEGPLRLKEEYVEGMLETPTVIEEAVPEQLKSALGQAATTLQQLPALIKDTLASGLRIPLSGSFERFFMISYLDEEILIVRDTEGVPEVLTRIETPSSTVVETIEYDS
Protein: Ubiquitin recognition factor in ER-associated degradation protein 1 (Ubiquitin fusion degradation protein 1) (UB fusion protein 1) (Q92890)
Organism: Homo sapiens (Human)
Function: Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures (By similarity). Acts as a negative regulator of type I interferon production via the complex formed with VCP and NPLOC4, which binds to RIGI and recruits RNF125 to promote ubiquitination and degradation of RIGI.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9ES53}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9ES53}.
Interaction partners:
- UBX domain-containing protein 7
- Transitional endoplasmic reticulum ATPase
- Nuclear protein localization protein 4 homolog
- FAS-associated factor 2
- FAS-associated factor 1
- NSFL1 cofactor p47
- Deubiquitinating protein VCPIP1
- Ubiquitin-associated domain-containing protein 2
- UBX domain-containing protein 10
- Derlin-1
Sequence:
MFSFNMFDHPIPRVFQNRFSTQYRCFSVSMLAGPNDRSDVEKGGKIIMPPSALDQLSRLNITYPMLFKLTNKNSDRMTHCGVLEFVADEGICYLPHWMMQNLLLEEGGLVQVESVNLQVATYSKFQPQSPDFLDITNPKAVLENALRNFACLTTGDVIAINYNEKIYELRVMETKPDKAVSIIECDMNVDFDAPLGYKEPERQVQHEESTEGEADHSGYAGELGFRAFSGSGNRLDGKKKGVEPSPSPIKPGDIKRGIPNYEFKLGKITFIRNSRPLVKKVEEDEAGGRFVAFSGEGQSLRKKGRKP
Protein: GH26960p (Porin2, isoform A) (Porin2, isoform B) (Voltage-dependent anion-selective channel protein 2) (Q9VKP2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004294}.
Interaction partners:
Sequence:
MAAKTPTYPDLGKLARDLFKRGYHPGIWQIDCKTLTNSGIEFFTTGFASQDNSKVTGSLQSKYKIEDQGLTLTERWNTENWLFGEIMHRDKLAQGLMLAVEAKFQPGSNEADGKFKMGYAQDNFNFLADIGLNSEPILNCSLVVGHKEFLGGVGTEFDVGNTELKGWKVALGWTNETATLHGELKNGDTWLASLFYKASEKIDAGIEVTKGAGGGEAAEGEQQGGDVVVNLGMIYHLEEDALVRAKVNNLVELGLGYEQKLRDGITASISAVLDCNNFKDGNHRFGVGIALQC
Protein: High affinity immunoglobulin gamma Fc receptor I (IgG Fc receptor I) (Fc-gamma RI) (FcRI) (Fc-gamma RIA) (FcgammaRIa) (CD antigen CD64) (P12314)
Organism: Homo sapiens (Human)
Function: High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells.
Subcellular location: Cell membrane {ECO:0000269|PubMed:12756162, ECO:0000269|PubMed:8611682}; Single-pass type I membrane protein {ECO:0000269|PubMed:12756162, ECO:0000269|PubMed:8611682}. Note=Stabilized at the cell membrane through interaction with FCER1G.
Interaction partners:
- Putative high affinity immunoglobulin gamma Fc receptor IB
- Low affinity immunoglobulin gamma Fc region receptor III-A
- Insulin-like growth factor 1
- Tyrosine-protein kinase SYK
- High affinity immunoglobulin epsilon receptor subunit gamma
- Tyrosine-protein kinase HCK
- Transcription factor PU.1
- Insulin-like growth factor 2
- Tyrosine-protein kinase Lyn
- Low affinity immunoglobulin gamma Fc region receptor II-a
Sequence:
MWFLTTLLLWVPVDGQVDTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLNGTATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEGEPLALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSAGISVTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYMGSKTLRGRNTSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQVLGLQLPTPVWFHVLFYLAVGIMFLVNTVLWVTIRKELKRKKKWDLEISLDSGHEKKVISSLQEDRHLEEELKCQEQKEEQLQEGVHRKEPQGAT
Protein: Polar tube protein 3 (Q8MTP3)
Organism: Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Function: Involved in the sporoblast-to-spore polar tube biogenesis. Plays a role in the control of the polar tube extrusion as part of a specific response to ionic stimuli.
Subcellular location: Spore polar tube {ECO:0000269|PubMed:12076771}.
Interaction partners:
Sequence:
MLLFLLCLYSMVARGDLGSRSSSHAVHHHHSKEGKNASGMDYGNRSTRNARVKVRLHNHNDDSQDGHHHHKVHRSHGGSIKPHNQKHAKLIRNMIGTHENDPENLTHEEKDLANMAAHGNLDALDMLYRNGSITPDVAESVGGSIPGGITEPVVIQPAESSPMEVNEEARVVDTMSPPDYSDPTGVYVSNGVATGRTNEEQAEINVLNRNENPIDDGIAEEAYSSLLSVGHSLPVAKAVADEIKDANVRKMLRTKRAYDISQPPVNPVYIPQAELARATNSKDVVSDTDRQMFMKKVFEEYIRQGAPVERANFEAGQAGFLIDEYNENLASGLSPDAAYEKAMSLVDLNYQHATRAAAIAGGGQVAAQNAADRSLIEETSANEMVKTPSGLRPEVLKKKEEAINSKKLDRAQDLSSYLTKLHIVEPVNRAHQKLSQAAALKDAASMEGLDNPVVQEKILTDVAASSAEDLAKAHENLENVKTQLKPGGRKTNALNFLSKVLTEKAIKDVNQRNEEMQKEAVKAQKEANENSAVKSAEEHLAKAAEQQIINNEGKSVFSKVLESTGDISEAAKAREEAERAMAETLRHQREARKAEVMKMLGPMGMNSSVKEAVEHMATAHAGLNVVGSDLNELNKKYEEEVAHQSNIEELLRETATSNLEVKEVIPPTTSRVGISEGKIKLPLKGFSNEEPKTEEETIVQSRQRNRRNQVRNKVIGTPVESGLNVVEMEDGYMHISEAAKALKINKGKVFYPESAKGIMEKQKLDTSLLEHKFNTGERAGLDKGVGYYEADASGFTLPLPSPLNPVPTSTMTNEEKSLNIGHAFELEIEDGELIQTPWIEFVKDMRPMVNGRMAHEAEVAAASEMKSRVEEEKKAKNLEGITTEVYTNPDGSKFVEVSSPYGVPEIMTMDQAVESLKSVGSSSVGAVSEEAKKQTPEVPLDMAVTNSVKGSEESFVSSVLSTIQKIGNGKALAKRNAFNGKVDGEKAAIVDEYNKELINEHLSPSSTVEARVRNSIISKAESYARSMGISTQSFLNMISQLPDSSIKEMISYNEAPPSARKDVAETHFYNQIASILPDSKTANTGSVTEMIFNNISTVTHEPNTVGGEILEQMTVPNLKTIEQVETKKTPTGTTQVSVSVPNDPGKIQVLGEVKFKGNPTTTPSSGRRPASNQAVAPANVVPGPMVPSSGRNPLKPGARLPANNGPVSNAPAARIPAGQPDHTMRGFSHSFPNNPQAPGIGATPSPAVGYSGKIAR
Protein: Doublesex- and mab-3-related transcription factor A1 (Doublesex- and mab-3-related transcription factor 4) (Q8CFG4)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00070}.
Interaction partners:
Sequence:
MERLPHGRRDRSGGCRPHLAPGRAAAPASAARSVSSGIPVSATFLRPPGLFLRSTASSGRAGCAPGPGLDRALGAVGCGYPRTPKCARCRNHGVVSALKGHKRFCRWRDCACAKCTLIAERQRVMAAQVALRRQQAQEESEARGLHRLLYQGSSGSGAQASGGSGRTESPQVLNNPMAVAVLGAGASRHPGSRSVPTFEVFQQDYADRKQEPKQRNCESCQSRQEEPVSNTHHHSLGSSKGNVTVEKQGFMSSIPEHPDKSTIILSPCPTDQSGGEDSPRSFSSSDLESGNESEWARDYIATRASLSTVTSRPRDPLGILTRIFPGYKHSRLEGILQFCKGDVVQAIEQILNGREHKPDCRDLARADLENAAFQRASDFSLAGIGFGTLSNKSALSPLEAASAAYGGDSTLYSFNPRLAFSPLRLAYSSPGRALSGFVSPYLTPGLVPALPFRPTLDYAFPGMIREPSHLPSKHLVAGGRLYFRPNQEHL
Protein: Malic enzyme (F1N3V0)
Organism: Bos taurus (Bovine)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Fumarate hydratase, mitochondrial
- Pyruvate carboxylase, mitochondrial
- Malate dehydrogenase, cytoplasmic
- Malate dehydrogenase, mitochondrial
- Pyruvate kinase
- Pyruvate kinase
- L-lactate dehydrogenase A chain
- Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
- L-lactate dehydrogenase B chain
- Citrate synthase, mitochondrial
Sequence:
MEPRTPRRRHTPQRGYAVTRNPHLNKDLAFTLEERQQLNIHGLLPPSFISQDVQVLRVLKNFERLNSDFDRYLLLMDLQDRNEKLFYKVLMSDIEKFMPIVYTPTVGLACQQYSLAFRKPRGLFISIHDRGHISSVLNAWPEDVIKAIVVTDGERILGLGDLGCNGMGIPVGKLALYTACGGMNPQQCLPVMLDVGTENEELLKDPLYIGLRQRRVRGPEYDDFLDEFMEAVSLKYGMNCLIQFEDFANINAFRLLRKYQNQYCTFNDDIQGTASVAVAGILAALRITKNKLSDQTVLFQGAGEAALGIAHLIVMAMEKEGLSKEQAIEKIWLVDSKGLIVKGRAALTQEKEEFAHEHKEMKNLEAIVQDIKPTALIDDDFENKDENPNKNKCLLHDSNHRVAAIGGAFSEQIIKDMAAFNERPIIFALSNPTSKAECTAEQCYKLTKGRAIFASGSPFDPVTLPSGKTLYPGQGNNSYVFPGVALGVVACGLRHITDKIFLTTAEVIAQQVSDKHLEEGRLYPPLDTIRDVSLKIAEKGIMLD
Protein: Uncharacterized protein (Q384M7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MIRQCVKTIPRWQPAFVHTQRHWKVDAKRPYKRRSSNPQTVREKGNFHRDMRFSKLRPLPTVPWLQDRRRTYMDDAERLYGRKENWQNIKDRAMREKLSSLLQDYLKDTTGAAMLETRNARKYMRLCEQMDAEYRSFVAAAAFSSPKHLRTHIMTALKESDKGSKKSRWCQETVCSERAATLHEEDRHTGECGERCGVNVASQEDAAQKRRLQGEWANLENTPAMMDLTHKEERTSSYSAFPFLRQRALENKETLDPSLVDWTAKYFPDDDDRTFTTPPKLRGDTGEGDSEEVPSPEILNVRKSVGGSDSLFPKPNVYRRLRRSLRVHEDVNRSTFDAEGAFYCVRRQGSEEDRAPKPCPVRGSGAHGDRNNEVIKVAWDTVARAKEMGYSADVLRAKERLIRLTRGEHPDTIP
Protein: Epididymis secretory protein Li 10 (V9HWI1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAVKKIAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSSRLPSEGPRPAHVVVGDVLQAADVDKTVAGQDAVIVLLGTRNDLSPTTVMSEGARNIVAAMKAHGVDKVVACTSAFLLWDPTKVPPRLQAVTDDHIRMHKVLRESGLKYVAVMPPHIGDQPLTGAYTVTLDGRGPSRVISKHDLGHFMLRCLTTDEYDGHSTYPSHQYQ
Protein: Zinc finger protein 780A (O75290)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MVHGSVTFRDVAIDFSQEEWECLQPDQRTLYRDVMLENYSHLISLGSSISKPDVITLLEQEKEPWMVVRKETSRRYPDLELKYGPEKVSPENDTSEVNLPKQVIKQISTTLGIEAFYFRNDSEYRQFEGLQGYQEGNINQKMISYEKLPTHTPHASLICNTHKPYECKECGKYFSRSANLIQHQSIHTGEKPFECKECGKAFRLHIQFTRHQKFHTGEKPFECNECGKAFSLLTLLNRHKNIHTGEKLFECKECGKSFNRSSNLVQHQSIHSGVKPYECKECGKGFNRGAHLIQHQKIHSNEKPFVCKECGMAFRYHYQLIEHCQIHTGEKPFECKECGKAFTLLTKLVRHQKIHTGEKPFECRECGKAFSLLNQLNRHKNIHTGEKPFECKECGKSFNRSSNLVQHQSIHAGIKPYECKECGKGFNRGAHLIQHQKIHSNEKPFVCRECEMAFRYHCQLIEHSRIHTGDKPFECQDCGKAFNRGSSLVQHQSIHTGEKPYECKECGKAFRLYLQLSQHQKTHTGEKPFECKECGKFFRRGSNLNQHRSIHTGKKPFECKECGKAFRLHMHLIRHQKLHTGEKPFECKECGKAFRLHMQLIRHQKLHTGEKPFECKECGKVFSLPTQLNRHKNIHTGEKAS
Protein: UPF0234 protein Rv0566c (P9WFK9)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Probable monooxygenase
- Glycerol-3-phosphate dehydrogenase [NAD
Sequence:
MADSSFDIVSKVDRQEVDNALNQAAKELATRFDFRGTDTKIAWKGDEAVELTSSTEERVKAAVDVFKEKLIRRDISLKAFEAGEPQASGKTYKVTGALKQGISSENAKKITKLIRDAGPKNVKTQIQGDEVRVTSKKRDDLQAVIAMLKKADLDVALQFVNYR
Protein: Uncharacterized protein (Q38E96)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MKAARSNGGRAGNGYTKSGMINSVAATQSQPRVVFTNTVTAPSVLLEKLRTIFSEVTICLKDKNAPSSADDFINVVEDGLRALKVAKAAKCERVQREAEADTSNAKCPKPERSGTDEQEKPEREISGWLRAVKQSLVKNKKISPKPIADEEQQREEILAARHASALRSEERQRIAEEKRLEKIQEMKLKLEAAEERGALAKERRRQAEERLRIDTMERLESGARRVEEAREQTKERARRGISRVEEVRLNNELRHQAKVLLLDRKMSEVEHNQEQKREELQRLAQERNEAILAAAERRRSLGQERMERQRQREQQRRENLRRLEEQKKLEKDMKGQRAEEWEKKVQQRQRAASAEAEARSRKAEERIQQSAQLREEKITKLRQKLEEQEQKIKEARQRKEREPDTKLTIAELMPTIPREEGEEMEQKFLKVLSMITRQGRSFIDKYQRESLIDQKDLNRSKLKLTISRLGSGISPAPVTQVRQSLREILEAPDLGDTDHEYMRYFNAYENIIGVILESRRTNNMSVLRLAHEALLRFLADKNEGRKHIVSFVRSGNLAPLLQCISEEIKGLKRQSRSVPLDAMLEALHLCFEGVTSAVQADTSLSSVRELLLSSFDSTNIEKYCIAVVKVCSDEEDLDVAHSATRILSSKISILNRRKGGCPIALVQEAASSFFALLQNILTPNGCSLSELSPVLSARRVTVVCVAFNALNCLARWNLETLQELLHDSPTNKRTGAHSGSNTIPTESSNTFTRTELFHMLNGFFTYVQSHTDSLEAIKEENPARGAVGGSFEEALKFGVSAEQMPLLARTEAISCATSGKVSVTNRQQNNLRGALHECLLLIGYLSIQDPEIQDIFAWGKGKSLLSKILSTMPFQYFTTGRHIFYPTLLTILVDSGDNVTLAKEEMDTRSLLEFIREEYQSLPKKSKLHALQRYNELRSEALANKERAATEAAKNAQPTSWADLLGGDDDEFLILAQKQMELKPLETKPVETRHPLWTPEKERFAKALKNQALTPSGYFKIEKRLPITLWPTVIDQLAVVAGEEREGLIDSAV
Protein: Asparagine synthetase domain-containing protein C4F6.11c (O74397)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Glutamate synthase
- Probable asparagine synthetase
- CTP synthase
- Glutamine synthetase
- Tryptophan synthase
- Inosine-5'-monophosphate dehydrogenase
- Probable NAD-specific glutamate dehydrogenase
- Probable glutamate 5-kinase
- Probable NADPH:adrenodoxin oxidoreductase, mitochondrial
- Glutamyl-tRNA
Sequence:
MCGILFALAEDRDNLLESPSFSALRKRIRARGPDFFGKHKLNSGPWNLHFESSVLHLRGPSDHLTPQPHVDSFGNVLCWNGEIWQINHSDHHKFTLNRNENDGAKLFELLNNNPGDIEKILGSIQGPFAFVYYQVRTNTLWWGRDRLGRRSLLYSLRDSNFVLSSVGNSSDFREVEPGFHSVQVDLIPKINFSKSLMQLEKTNPLPPVDESFLMGSISSDTVDTLHTYLIKALQDRVLTIPKLCSSNLDCSHYSRVCVLYSGGVDCGVLARLMHDIVPNNESIDLINVAFENPRFTETYRDRETGLLPDNFDAYDVCPDRQTGLQGWQELISVCPARKWNFVAINVPYTEVCEAQEIVKTLIYPNDSVMDLSIGLAFYFASQGRGVLLQNVDDIKLKHQLPSYTIKAKVLISGLGADEQLGGYMRHLRAFERKGMAGLEEELQLDIDRIPHRNLGRDDRVMSNQGKEVRYPFLDERLMALFSKMKTTDKMRLDLVGGDKLILRELGRRLGCPLASQEKKRAIQFGSKAAKMTPGTGRTSGRKKLEVCI
Protein: Tet-like dioxygenase 1 (EC 1.14.11.80) (NgTet1) (D2W6T1)
Organism: Naegleria gruberi (Amoeba)
Function: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC), and thereby plays a role in active DNA demethylation. Also mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC), and conversion of 5fC to 5-carboxylcytosine (5caC).
Interaction partners:
Sequence:
MTTFKQQTIKEKETKRKYCIKGTTANLTQTHPNGPVCVNRGEEVANTTTLLDSGGGINKKSLLQNLLSKCKTTFQQSFTNANITLKDEKWLKNVRTAYFVCDHDGSVELAYLPNVLPKELVEEFTEKFESIQTGRKKDTGYSGILDNSMPFNYVTADLSQELGQYLSEIVNPQINYYISKLLTCVSSRTINYLVSLNDSYYALNNCLYPSTAFNSLKPSNDGHRIRKPHKDNLDITPSSLFYFGNFQNTEGYLELTDKNCKVFVQPGDVLFFKGNEYKHVVANITSGWRIGLVYFAHKGSKTKPYYEDTQKNSLKIHKETK
Protein: N-chimaerin (A-chimaerin) (Alpha-chimerin) (N-chimerin) (NC) (Rho GTPase-activating protein 2) (P30337)
Organism: Rattus norvegicus (Rat)
Function: GTPase-activating protein for p21-rac and a phorbol ester receptor. Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance.
Interaction partners:
Sequence:
MPSKESWSGRKTNRATVHKSKQEGRQQDLLIAALGMKLGSQKSSVTIWQPLKLFAYSQLTSLVRRATLKENEQIPKYEKVHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHITKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIVDPDEQLETLHEALRSLPPAHCETLRYLMAHLKRVTLHEKENLMSAENLGIVFGPTLMRSPELDPMAALNDIRYQRLVVELLIKNEDILF
Protein: DExH-box ATP-dependent RNA helicase DExH15 chloroplastic (EC 3.6.4.13) (ATP-dependent RNA helicase ISE2) (Protein EMBRYO DEFECTIVE 25) (Protein INCREASED SIZE EXCLUSION LIMIT 2) (Protein PIGMENT DEFECTIVE 317) (B9DFG3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: RNA helicase involved in group II intron splicing. Essential protein required during embryogenesis. Involved in post-transcriptional gene silencing. Modulates the determination of cell fate. Necessary for normal plasmodesmata (PD) development and aperture regulation.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:18431481, ECO:0000269|PubMed:22106293, ECO:0000269|PubMed:26147377}. Cytoplasmic granule {ECO:0000269|PubMed:17601829}. Note=Localizes to granule-like structures, probably stress granules (SGs), which number increases upon stress. {ECO:0000269|PubMed:17601829}.
Interaction partners:
- Tetratricopeptide repeat protein SKI3
- DEAD-box ATP-dependent RNA helicase 47, mitochondrial
- Ribosomal RNA-processing protein 42
- Exosome complex component RRP4 homolog
- Ribosomal RNA-processing protein 43
- DEAD-box ATP-dependent RNA helicase 50
- Nuclear nucleic acid-binding protein C1D
- D-aminoacyl-tRNA deacylase
- At5g38890
- Curculin-like
Sequence:
MNTLPVVSLTASSSFKFFHFPSLHRSLSHSPNFSFTKSLILNPNHLSFKSTLNSLSPSQSQLYEEEDDEEEEEEDEDDDDEAADEYDNISDEIRNSDDDDDDEETEFSVDLPTESARERVEFRWQRVEKLRSLVRDFGVEMIDIDELISIYDFRIDKFQRLAIEAFLRGSSVVVSAPTSSGKTLIAEAAAVSTVAKGRRLFYTTPLKALSNQKFREFRETFGDDNVGLLTGDSAINKDAQIVIMTTEILRNMLYQSVGMASSGTGLFHVDAIVLDEVHYLSDISRGTVWEEIVIYCPKEVQLICLSATVANPDELAGWIGEIHGKTELVTSTRRPVPLTWYFSTKHSLLPLLDEKGINVNRKLSLNYLQLSASEARFRDDDDGYRKRRSKKRGGDTSYNNLVNVTDYPLSKNEINKIRRSQVPQISDTLWHLQGKNMLPAIWFIFNRRGCDAAVQYVENFQLLDDCEKSEVELALKKFRVLYPDAVRESAEKGLLRGIAAHHAGCLPLWKSFIEELFQRGLVKVVFATETLAAGINMPARTAVISSLSKKAGNERIELGPNELYQMAGRAGRRGIDEKGYTVLVQTAFEGAEECCKLVFAGVKPLVSQFTASYGMVLNLVAGSKVTRKSSGTEAGKVLQAGRSLEEAKKLVEKSFGNYVSSNVTVAAKQELAEIDNKIEILSSEISDEAIDKKSRKLLSARDYKEITVLKEELREEKRKRAEQRRRMELERFLALKPLLKGMEEGNLPFICLEFKDSEGREQSVPAVYLGHIDSFQGSKLQKMMSLDESFALNLIEDELAADEPGKPNVKPSYYVALGSDNSWYLFTEKWVRTVYRTGFPNIALALGDALPREIMKNLLDKADMQWDKLAESELGSLWRLEGSLETWSWSLNVPVLSSLSDEDEVLHMSEEYDNAAQKYKEQRSKISRLKKKMSRSEGFREYKKILENANLTVEKMKRLKARSRRLINRLEQIEPSGWKDFMRISNVIHESRALDINTHLIFPLGETAAAIRGENELWLAMVLRNKALVDLKPPQLAGVCASLVSEGIKVRPWRDNNYIYEPSDTVVDMVNFLEDQRSSLIKLQEKHEVMIPCCLDVQFSGMVEAWASGLSWKEMMMECAMDEGDLARLLRRTIDLLAQIPKLPDIDPVLQRSAAAAADIMDRPPISELAG
Protein: Eukaryotic translation initiation factor 4 gamma 2 (A0A8I6ADP1)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MTTPQQTTPQMKKNDMMQSSGNILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRLAEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPLLPEEEEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDMGEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREHHWVPRKAFLDNGPKTINQIRQDAVKDLGVFIPAPMAQGRNDFFLEGPFMPPRMKMDRDPLGGLADMFGQMPGSGIGTGPGVIQDRFSPTMGRHRSNQLFNGHGGHIMPPTQSQFGEMGGKFMKSQGLSQLYHNQSQGLLSQLQGQSKDMPPRFSKKGQLNADEISLRPAQSFLMNKNQVPKLQPQITMIPPSAQPPRTQTPPLGQTPQLGLKTNPPLIQEKPAKTSKKPPPSKEELLKLTEAVVTEYLNSGNANDAVSGVREMRAPKHFLPEMLSKVIILSLDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLEQCPKLEVDIPLVKSYLAQFAARAIISELVSISELAQPLESGTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKMLPEIDQNKDRMLEILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIKDNISPKLHVDKGFVNILMTSFLQYISSEVSPPSDETDSSSAPSKEQLEQEKQLLLSFKPVMQKFLHDHVDLQVSMLLRFFVHFYDMEIIEEEAFLAWKEDITQEFPGKGKALFQVNQWLTWLETAEEEESEEEAD
Protein: SUMO-activating enzyme subunit (Q7KUA4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Dorsal interacting protein 4
- Activator of SUMO 1
- Small ubiquitin-related modifier
- Suppressor of variegation 2-10, isoform I
- Nedd8-conjugating enzyme UbcE2M
- DNA repair protein Rad60
- GH15225p
- E1 ubiquitin-activating enzyme
- E3 SUMO-protein ligase RanBP2
- Ubiquitin-like protein NEDD8
Sequence:
MAAAINGVFPPTLQELVKKSKVLVVGAGGIGCEVLKNLVLSGFTDIEIIDLDTIDLSNLNRQFLFHREHVGKSKARVARESALSFNPDAKITAYHDSVTSTDYGVNFFKKFDLVLSALDNRAARNHVNRMCLNADVPLIESGTAGYNGQVELIKRGLTQCYECTPKDKQRSFPGCTIRNTPSEPIHCIVWAKHLFNQLFGESLEDEDISPDAADPDAKEKDGGDGNGEPKGDGKEKGEESKEEKEAKEDTANGNIMRINTRQWAKDCNYDAGKLFNKFFNEDITYLLRMSNLWKTRKAPVPVQWDTLLPEGSSGDQKDVAKQHHKVWSIEECAQVFANSLKELSANFLKLEGDDTLAWDKDDQPAMDFVAACANVRSHIFDIERKSRFEIKSMAGNIIPAIATTNAITAGISVMRAFKVLEAKWEQCKAVYARLRPNARNHFLVPDASLPGPNPNCHVCASDPAITLKIDTKRMRIKELRDEVLVKTLNMLNPDVTVQSNGSILISSEEGETECNDGKLLSELNIVDGVILKCDDFFQNYELSIIISHFDAERDENLFEVVADASQLKPKDEDQKEAVKDKEDEPKSAKKRSTNGEGDSKDDGPSTSKRSRPNEVVEEDDDDCLVIEEDEDQADVVVVATDKLSVQSPPKSGSKRKPCEVIEDEDITEILESSDDEPAGPTKCKRSRLDDSNPVAVISID
Protein: AP2/ERF and B3 domain-containing transcription repressor RAV2 (Ethylene-responsive transcription factor RAV2) (Protein RELATED TO ABI3/VP1 2) (Protein RELATED TO APETALA2 8) (Protein TEMPRANILLO 2) (P82280)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Transcriptional repressor of flowering time on long day plants. Acts directly on FT expression by binding 5'-CAACA-3' and 5'-CACCTG-3 sequences (Probable). Functionally redundant with TEM1.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Adagio protein 3
- MADS-box protein SOC1
- AP2/ERF and B3 domain-containing transcription factor RAV1
Sequence:
MDSSCIDEISSSTSESFSATTAKKLSPPPAAALRLYRMGSGGSSVVLDPENGLETESRKLPSSKYKGVVPQPNGRWGAQIYEKHQRVWLGTFNEQEEAARSYDIAACRFRGRDAVVNFKNVLEDGDLAFLEAHSKAEIVDMLRKHTYADELEQNNKRQLFLSVDANGKRNGSSTTQNDKVLKTREVLFEKAVTPSDVGKLNRLVIPKQHAEKHFPLPSPSPAVTKGVLINFEDVNGKVWRFRYSYWNSSQSYVLTKGWSRFVKEKNLRAGDVVTFERSTGLERQLYIDWKVRSGPRENPVQVVVRLFGVDIFNVTTVKPNDVVAVCGGKRSRDVDDMFALRCSKKQAIINAL