wanglab/gogpt-training-data huggingface dataset:
Protein: Huntingtin-interacting protein 1 (F1R6L2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Cyclin G-associated kinase.
Sequence:
MDRVKSSMQQVPNPIPKVLSRRAGGANSLEVEKENFERNQAVSINKAINTQEVAVKEKHARTCILGTHHEKGAHTFWLAVNRLPLSSNAVLCWKFCHVFHKLLRDGHPNVIKDSMRHKADLNDMSRMWGHLSEGYGKLCSIYLKLLITKMEFHIKNPRFPGNLQMSNRQLDEAGENDVNNFFQLTVEMFDYLECELNLFLGVFSSLDMSRSVSVTAAGQCRLAPLIQVILDSSHLYDYTVKLLFKLHSCLPADTLQGHRDRFQEQFKKLKSLFYRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHISPVVVIPAEASSPESEHVVETEDLVDTDIPPLTGTGDSKFDDLFGTSAATDPFNFNSQNGMRKDDKDRLIEQLTAELQALKEELESFRLESGRLCQALRGRVNELEAELAEQTHLKQQALGESEFLRAELDDLRRVKEDTEKEQRSLSEIERKAQANEQRYTKLKEKYTELVQSHADLLRKNAEVTRQMTVARAAQDEVENVKKEMQDRLKVAQDSASQQEKAQLEQLQALQAELMSSRTELETLKSTVTSSQQSNEQLGTQLSALVAEKAGLVETVSRKEVELSGLGAELERLQSSLTNERESGVKAAEALQNQLNEKESREQALESELVSLRWASLRAALEEAGKIVQDSLNQLEDPAHISCTSSADYLVSRCQVALDCVERLRSSRDGFVSDNTDVSGLVRAVTQFAHLVGDVIVQGSATSHMVPVEQADALADSVKACGAEALTLLCQLKEQESMGAADCSRLRTALDSVKALGEKLRPRGLELQQGELGDLVEQEMAATSAAVESAAARIEEMLNKSRAVDTGIKMEVNERILASCTDLMQAIRVLVLSSKDLQRDIVESGRGAASMKEFYAKNSRWTEGLISASKAVGWGATMLVDAADQVVQGKGKFEELMVCSHEIAASTAQLVAASKVKAEKGSSNLSRLQQASKGVTQATAGVVASTKSGKSQIEDTETMDFSAMTLTQIKRQEMDAQVLVLELETRLQKERERLGELRKKHYELAGVAEGWGGEEEGTG
Protein: Indoleacetamide hydrolase (EC 6.3.5.-) (E0SI86)
Organism: Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
Interaction partners:
- Tryptophan 2-monooxygenase
- Amidase
- Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase
Sequence:
MYSEYTLESLCSDLRRGIVSAADIRQQALNAEAQQRHLNCFIRIDDAEEQFEKVKDVHKGGPLYGIPVSFKDNICVAGLPVTVGTQGMADCIATHDAAIVRKLKSLGAVVAGKNNMNELCFGVTSCEPYWGAVENPSAPGYSIGGSSSGCAAAVAAGIVPVAIGTDTGGSARIPASFCGITGFRPTSGHWSSSGIIPVSHTKDSPGLITRTASDAHFLYTHLSSDDVSPTEQGHFPCRIGLPLSMWSELDDDVMTHCRYAINQLILAGFECVDVDDAAVFSLNQTITFTLPIYEFFIDFPRTLLSLGWENRIATVFDNISDKNVHKIIQEHLVGGRISPADYVSVVRNIGRLRLDMDTLFSTYGVDMLVYPTVPRQVPHLSQTGRPELFAELIRNTDLASNAAMPSITLPVAPEGALPVGLSFDALRGRDRYLLGMATRIETIIKP
Protein: GH14769p (Par-1, isoform Q (EC 2.7.11.-, EC 2.7.11.26)) (Q8MQR8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MGQTSSHRQMHHSSNNNNKEEPPQPASQFGNRRTSTRKSTSSSKHYPTLVQPLRKDELSLLRDSLLRNGSIMRKNPERRPVTISELKPVNTGQGTSGSVLPITAEDAAGGSSSSITQLMAFQLPVDRSAKTDDLAAESSASAAAAVAPKEGRNEFYIVGDGYHRTDHCYYRSPNGDFHKLPSDSFHKMSEGCFVRMADGVFRRLEVPTKAQISRRSSRAEEIGDATSQGNGSAATNVKSQLMRFLKRSKSHTPATIAKLQREKEEARAERKQRLSNALRQKNLAATNAASAAAANSSYASGGGGGTVSSRNNKIVVTMIENGGLPIVATSKAERPKAKESASSSDKARNSRIFVTPH
Protein: Ileal sodium/bile acid cotransporter (Apical sodium-dependent bile acid transporter) (ASBT) (Ileal Na(+)/bile acid cotransporter) (Ileal sodium-dependent bile acid transporter) (IBAT) (ISBT) (Na(+)-dependent ileal bile acid transporter) (Sodium/taurocholate-cotransporting polypeptide, ileal) (Solute carrier family 10 member 2) (Q62633)
Organism: Rattus norvegicus (Rat)
Function: Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Transports various bile acids, unconjugated or conjugated, such as cholate and taurocholate. Also responsible for bile acid transport in the renal proximal tubules, a salvage mechanism that helps conserve bile acids. Works collaboratively with the Na(+)-taurocholate cotransporting polypeptide (NTCP), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation (By similarity).
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Solute carrier family 51 member A
- SLC51 subunit beta
- Bile salt export pump
- Bile acid receptor
- Cytochrome P450 7A1
- Gastrotropin
- Fibroblast growth factor
- Nuclear receptor subfamily 0 group B member 2
- Cytochrome P450 family 8 subfamily B member 1
- G-protein coupled bile acid receptor 1
Sequence:
MDNSSVCSPNATFCEGDSCLVTESNFNAILSTVMSTVLTILLAMVMFSMGCNVEINKFLGHIKRPWGIFVGFLCQFGIMPLTGFILSVASGILPVQAVVVLIMGCCPGGTGSNILAYWIDGDMDLSVSMTTCSTLLALGMMPLCLFIYTKMWVDSGTIVIPYDSIGISLVALVIPVSIGMFVNHKWPQKAKIILKIGSIAGAILIVLIAVVGGILYQSAWIIEPKLWIIGTIFPIAGYSLGFFLARLAGQPWYRCRTVALETGMQNTQLCSTIVQLSFSPEDLNLVFTFPLIYTVFQLVFAAIILGMYVTYKKCHGKNDAEFLEKTDNDMDPMPSFQETNKGFQPDEK
Protein: UPF0743 protein YCR087C-A (P37263)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Ribosome biogenesis protein RPF2
- Small ribosomal subunit protein uS19
- H/ACA ribonucleoprotein complex subunit NHP2
- Protein PXR1
- Ribosomal RNA-processing protein 14
- ATP-dependent RNA helicase HAS1
- Ribosome biogenesis protein BRX1
- Nucleolar complex protein 2
- Ribosomal RNA-processing protein 1
- Ribosome assembly factor MRT4
Sequence:
MVTFNCEVCNDTVPKKNTEKHYYRCPNAYYTCIDCSKTFEDGVSYKNHTSCISEDEKYQKALYKGNKKQKQKQQQKQQQKQHQHQPVATPAKKVEKPVIKKAEKVEKTSNGIELHKGKSLYKILKTMKDKGAKKTFLKSLVVDSEGQIRYAKE
Protein: GH09123p (Q9VFC9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- RE59088p
- AT03047p
- trypsin
- Trypsin eta
- Metalloendopeptidase
- RE36938p)
Sequence:
MAHSMLKLGMMCGILHLLTFGVIAEDQLKNNTIVVHTPLQNYDQPNLQDYEECQVNRDNCINVCAGKQSCEDECPVCPDLYVKPLMVQGINDTNIVAPPQVPINTTNIIRLTNDINNIIEHQIQNRNEVNVQVNQNVSKVGGRFGLGYTDKGSCCYVVRLDRECKNEDGRDCRERSRQRICGEKCQARVMLAKIVVQCEAEDSDRCHETIEYVPRRRRTLQRRTPKATRCHYTGNSWPYFNCGQNPGQNSDFAQPTRPKTSICEHCLNYPYGYILQNGLPAQCAGCFQGYGAPLMYNPPWMYNPYYVAYPAFNNIPAIQNNNNGNSGDTSVDKTIADDDDDGWTLCDDIEKCLDAEYKGSQNSGSPEHLVDDDDYNVSVQRRRRRPSRHHFVRSAYSKRNRKHN
Protein: Trehalose-phosphatase (EC 3.1.3.12) (Trehalose-6-phosphate phosphatase) (TPP) (A8NS89)
Organism: Brugia malayi (Filarial nematode worm)
Function: Catalyzes the hydrolysis of trehalose 6-phosphate to trehalose and phosphate; prevents the accumulation of toxic levels of trehalose 6-phosphate.
Interaction partners:
- DnaJ homolog subfamily C member 10
- GrpE protein homolog
- Bm5434.
- Heat shock protein 90
- BMA-DNJ-15
- 10 kDa heat shock protein, mitochondrial
- Uncharacterized protein.
- BMA-DNJ-12
- Bm12893
- BMA-HSP-110
Sequence:
MTETVTDQGKQRSSKLQKNEAAKDEQVEGKGKETLESGTDKSAEQNSSLLVGQPDVIDNDNVQTVDDFKNLMYKMQETRRAIVFALLNEKDLTKDDVEILKRAYEKLTDNQTHSFQREMCTLTTKLSVNIGDETRGLEKDLKYLDALMNIRREEPNLLWPIIMSRVDLFSILANYHPKGKETFLKEYEDTVKFLKTFISSEAITGKKPIFITDWDGTMKDYCSQYATNLQPVYSAVGMTRFAASFTRISAVLTAGPLRGPGILDLTAMPIDGPVMFSGSWGREWWLSGKRVVHQDGITDEGFNALQRLDDEMKDLLHTSDYAPFALVGSGVQRKVDRLTLGVQTVCHHVTSELSNRYQMAVKERMHRVDPNSQILVFDPSTELEVEVVAHNSGIIWNKGNGVERLIKSLGDSLQSPGKILICGDTLSDIPMVRQAVKQNPDGVLAIFVGAKMSLREEVKQVIGDESRCCFVSCPDVIHAAMSQILNEHCIGK
Protein: Protein SHI RELATED SEQUENCE 1 (Protein STYLISH 1) (Q9SD40)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription activator that binds DNA on 5'-ACTCTAC-3' and promotes auxin homeostasis-regulating gene expression (e.g. YUC genes), as well as genes affecting stamen development, cell expansion and timing of flowering. Synergistically with other SHI-related proteins, regulates gynoecium, stamen and leaf development in a dose-dependent manner, controlling apical-basal patterning. Promotes style and stigma formation, and influences vascular development during gynoecium development. May also have a role in the formation and/or maintenance of the shoot apical meristem (SAM).
Subcellular location: Nucleus {ECO:0000269|PubMed:20154152}.
Interaction partners:
- Probable indole-3-pyruvate monooxygenase YUCCA4
- B3 domain-containing transcription factor NGA3
- Probable indole-3-pyruvate monooxygenase YUCCA1
- Electron carrier/iron ion-binding protein
- Ethylene-responsive transcription factor ESR2
Sequence:
MAGFFSLDGGGGGGGGGGNNQEDHRSNTNPPPPVSEAWLWYRNPNVNANANTNVNANAPSSSNAALGTLELWQNHNQQEIMFQHQQHQQRLDLYSSAAGLGVGPSNHNQFDISGETSTAGAGRAAAMMMIRSGGSGGGSGGVSCQDCGNQAKKDCSHMRCRTCCKSRGFECSTHVRSTWVPAAKRRERQQQLATVQPQTQLPRGESVPKRHRENLPATSSSLVCTRIPSHSGLEVGNFPAEVSSSAVFRCVRVSSVEDGEEEFAYQTAVSIGGHIFKGILYDLGPGSSGGGGYNVVAAGESSSGGGGAQQLNLITAGSVTVATASSSTPNLGGIGSSSAAAATYIDPAALYPTPINTFMAGTQFFPNPRS
Protein: Stolid, isoform H (Stolid, isoform I) (X2J9Z3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- Ca2+-channel-protein-beta-subunit, isoform L
- VWFA and cache domain-containing protein CG16868
- Voltage-dependent calcium channel type D subunit alpha-1
- Voltage-dependent calcium channel type A subunit alpha-1
- Uncharacterized protein
- Ca[2+]-channel protein alpha[[1]] subunit T, isoform F
Sequence:
MESKHWSCFVAIVLGVLIFKMHIFVAFADQDEDIPHNEVRNWALKFGVDLWEFGRQFTKMNEIKSRFKDNDIEVKRKDGIILLRELAAEVKNFMDFKRNAVMRLMDSAEQAALSELEGQGQAESPMGGQQHYDARRINEYNADGKLADGARHMDIRFMRRFERLPVNLSLSSILVPHGVDLDEPDVKSALQWSGHLDPLFQNNLEQDPALSWQYFGSSTGFLRRFPGTAWPPEGSKGSKLIHDFRTHNWFVQAASSPKDIMILLDASSSMTEKSFDLGMATAFNILDTLGEDDFVNLITFSEVVKTPVPCFKDRMVRATPDNIQEIKSAVKAIKLQDTANFTAGLEYAFSLLHKYNQSGAGSQCNQAIMLITESTSESHKDVIKQYNWPHMPVRIFTYLIGSDSGSRSNLHDMACSNKGFFVQINDYDEARRKVIDYALVMARPMIMYQADHPVHWSPVFVAGKSGGLGRDSEYQRRLVTTVSTPVFDRRNHSVRVANLLGVVGTDVPIEEIRKVIPQHKLGPNGYSFIVDNNGRVLYHPDLRPLGDANQYIDQLKPKYASVDITELELPETEFGNNNEPIEINKNLLNEMRGDMIKPKEGETEFTVMNHYDDSKRVSTRTHRYFYGPIEDTPFTLAIVLPEKYGSHEFVSQQEIRHSRNNVTEYFKGDNWRVHPDWVYCEYNSVSDLEKERESSGEYSSRDQEPSFGSPEEQVLHFLSRAGRPGWKWMSVRPKSPQPHHNMHSGSNGGNAPGSSHFGSQHQSSQGSRKAEPYFCDRALLQSLVRDAMVTDGLDRNTTGSSSGKEDKHPIATLMAILKRQGYQKFVVATSFVATRSGLLRWIDHVKRPEDTPEPHFSEDNVRAMDTSWYKRAIDQHSVEPDSFVYSVPFGSGYAIKSNATLVTASHAIFVEHRGHKAAAGVVGLQFQHDSLAKHFINITSACTGMTGCKRTCASDNLDCYVLDNSGFVIISEEMEHTGKFFGQIDGTIMDSLVQDRIYKRVTVNDYQGVCSDADNPYTAAGGILKPNRLGSWFFNHLLALSAAWLSLMPASLRAWPQEEYTYDNEDVVFVDNNYSDEYEFGNENEYNMQVDQEMDEFFTTADVEYTTPPPRQHKPHVGPRFSPDPHNARRCDLRTDLYMLQPERLNQGGQNNPLKGKLTNCHVSGCERPFSVQKIPHSNLILLVVDTLCPCGSKQLDIEPLEEAGVIGACSTRRQGQEQESRRRPKKCINYHPEEIEIQQCGRGSTLLHMSGSVIVAHLLMVTVTFVLANA
Protein: Protein sprouty homolog 2 (Spry-2) (O43597)
Organism: Homo sapiens (Human)
Function: Antagonist of fibroblast growth factor (FGF) pathways via inhibition of FGF-mediated phosphorylation of ERK1/2 (By similarity). Thereby acts as an antagonist of FGF-induced retinal lens fiber differentiation, may inhibit limb bud outgrowth and may negatively modulate respiratory organogenesis (By similarity). Inhibits TGFB-induced epithelial-to-mesenchymal transition in retinal lens epithelial cells (By similarity). Inhibits CBL/C-CBL-mediated EGFR ubiquitination.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10887178}. Cell projection, ruffle membrane {ECO:0000269|PubMed:10887178}. Note=Associated with microtubules in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor). {ECO:0000269|PubMed:10887178}.
Interaction partners:
- E3 ubiquitin-protein ligase CBL
- Growth factor receptor-bound protein 2
- Serine/threonine-protein kinase B-raf
- Epidermal growth factor receptor
- Dual specificity protein phosphatase 6
- Fibroblast growth factor receptor substrate 2
- Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
- Protein sprouty homolog 1
- Pro-epidermal growth factor
- Tyrosine-protein phosphatase non-receptor type 11
Sequence:
MEARAQSGNGSQPLLQTPRDGGRQRGEPDPRDALTQQVHVLSLDQIRAIRNTNEYTEGPTVVPRPGLKPAPRPSTQHKHERLHGLPEHRQPPRLQHSQVHSSARAPLSRSISTVSSGSRSSTRTSTSSSSSEQRLLGSSFSSGPVADGIIRVQPKSELKPGELKPLSKEDLGLHAYRCEDCGKCKCKECTYPRPLPSDWICDKQCLCSAQNVIDYGTCVCCVKGLFYHCSNDDEDNCADNPCSCSQSHCCTRWSAMGVMSLFLPCLWCYLPAKGCLKLCQGCYDRVNRPGCRCKNSNTVCCKVPTVPPRNFEKPT
Protein: RNA helicase (Q86L44)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- Uncharacterized protein
- 30S ribosomal protein S9
- 50S ribosomal protein L20
- Large ribosomal subunit protein bL17m
- Large ribosomal subunit protein bL27m
- Large ribosomal subunit protein bL33m
- Large ribosomal subunit protein mL46
- DNA
- Small ribosomal subunit protein uS7
- Small ribosomal subunit protein uS11
Sequence:
MTKNDLQTYIQQKRIGYLPVYHSECRGPDHEREYRTHIRVGEINSKHNNKIVYSDWYKNKKTAESCCAIKVLNYLNQQGREDLNNKYQEQKKTRQQQEQEIESPPPQQPQQLTYQTKQSIDSLFSKFISIDKNKIKDELIEKQKNDGNLLSGGFSYLHFNEPTQMEKDNEIERLKRTLGDLQQRVDTMNSIFQDENCNNLTLGQIKTIGMPIIKTLQQGDDGKPMEMNKSKPRDYQCELYRKSMEKDIICCLPTGLGKTLISCLVIKKMKQLNPSKQIVFIVDRIPLVIQQSDVIETETGLKVLSAHGETFKPVQLKQRFDVLVVIGDLFNKLLSNGDLNILSFCLIVIDEAHHIVKEHSFAKLLRDKLNTIPEICHPKILGLTASPAGKKDFFNTLLSLKLISKVSRCEIIKPTNQSIIPYINQKNIKIIPIPTNNLERHSIQILKDLISKYKPNLSNNQELFDSVTSVIDSNTLKGLGVGGGGGGSNSSTQNHNLNKFLSSFFEKINDFINFKMFGSAIPVGLNLKSFLIEEISNIDDVELQSEILAMVHSLPCDEEIADSISKLEIALQILDEKKSDDLKAIIFVKTRDVAKKVYSLLDQLRMGDRFSFIKPNLVVGHGSIGGMSISSQKKAIEEFRSDQCNVIVATSVVEEGFDVPECNIVIRLDPPTTVTANIQSRGRLRNRDSYFYGIVKVDDPREDNIYEFFKNQERYLEEAINFLKTGELPISLKQQNYTTQVNQVDEEMDTNSYFASASALVQEMVIQVKRHTFDFGIAWEHTPDGSGFFNAIATFYINKEAAHSHFKSGQNKKTAKENTCKSILQSGLIYNLIKNLE
Protein: Phosphotransferase (EC 2.7.1.-) (Q9GNE4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MLDAEVRELMQPFVLSDYQVQEVYSRFCLEVARGLKRSTHPQANVKCFPTYVQDLPTGDEMGKYLALDLGGTNFRVLLVSLKGHHDATVDSQIYAVPKDLMVGPGVDLFDHIAGCLAKFVEKHDMKTAYLPLGFTFSFPCVQLGLKEGILVRWTKGFDCAGVEGEDVGRMLHEAIQRRGDADIAVVAILNDTTGTLMSCAHRNADCRVGVIVGTGCNACYVEDVENVDLLRADFKKTKRSVIVNAEWGAFGEGGQLDFVRTEYDREVDEKSLNRSEQLFEKMTAGMYLGNLVRLVLLRALERKLIFKQSSRRPEFASVLQRNEEVFETRYISEIEDDSFPEFASTRKIVKNLFGLEKASVEDCQTLRYICECVAKRAATLVAIGVSGLVNRTSNRRVIVGMDGSVYRYHPEFDAYMRQTLQKLVKADKEWDIMLSEDGSGRGAALVAAVASKTK
Protein: Small ribosomal subunit protein uS8A (40S ribosomal protein S22-A) (P0CT58)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein eS7
- Elongation factor 3
- Small ribosomal subunit protein uS14
- mRNA export factor elf1
- Small ribosomal subunit protein eS21
- Small ribosomal subunit protein eS27
Sequence:
MVRQSVLADCLNNIVNAERRGRRQVLIRPSSKVIVKFLTVMQKHGYIDEFTEIDDHRSGKIVIQLNGRINKCGVISPRFNVKLKDIEKWVNQLLPSRQVGVIVLTTSRGIMSHNEARAKDAGGKILGFFY
Protein: Proline-rich receptor-like protein kinase PERK12 (EC 2.7.11.1) (Proline-rich extensin-like receptor kinase 12) (AtPERK12) (Protein INFLORESCENCE GROWTH INHIBITOR 1) (Q9ZUE0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Regulates the auxin-related MAX (More Axillary Growth) pathway during the shoot branching.
Subcellular location: Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Interaction partners:
- Protein kinase superfamily protein
- Transmembrane protein
- Proline-rich family protein
- Protein RALF-like 4
- Armadillo repeat only 1
- Membrane-anchored ubiquitin-fold protein 3
- non-specific serine/threonine protein kinase
Sequence:
MSDLGESPSSSPPAPPADTAPPPETPSENSALPPVDSSPPSPPADSSSTPPLSEPSTPPPDSQLPPLPSILPPLTDSPPPPSDSSPPVDSTPSPPPPTSNESPSPPEDSETPPAPPNESNDNNPPPSQDLQSPPPSSPSPNVGPTNPESPPLQSPPAPPASDPTNSPPASPLDPTNPPPIQPSGPATSPPANPNAPPSPFPTVPPKTPSSGPVVSPSLTSPSKGTPTPNQGNGDGGGGGGGYQGKTMVGMAVAGFAIMALIGVVFLVRRKKKRNIDSYNHSQYLPHPNFSVKSDGFLYGQDPGKGYSSGPNGSMYNNSQQQQSSMGNSYGTAGGGYPHHQMQSSGTPDSAILGSGQTHFSYEELAEITQGFARKNILGEGGFGCVYKGTLQDGKVVAVKQLKAGSGQGDREFKAEVEIISRVHHRHLVSLVGYCISDQHRLLIYEYVSNQTLEHHLHGKGLPVLEWSKRVRIAIGSAKGLAYLHEDCHPKIIHRDIKSANILLDDEYEAQVADFGLARLNDTTQTHVSTRVMGTFGYLAPEYASSGKLTDRSDVFSFGVVLLELVTGRKPVDQTQPLGEESLVEWARPLLLKAIETGDLSELIDTRLEKRYVEHEVFRMIETAAACVRHSGPKRPRMVQVVRALDCDGDSGDISNGIKIGQSTTYDSGQYNEDIMKFRKMAFGGDNSVESGLYSGNYSAKSSSDFSGNESETRPFNNRRF
Protein: PPPDE domain-containing protein (Q385N7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MPLCCCKDENNSTVDKIPDTIETGEVVLKRCAPPVLTRDDFVEVQVHVNVYSLLKRNGCFKKIGMGVFHCGIVVYGIEWGYGECMDPNTASGLFCVCPGHAAGSLYRTICLGVTTRSPEQVDTILHRLENEWRSADYHILAHNCNHFAQRFCDMLSTVQKLQLPAWCNRAARVCNKVVPRRLASYIHRMMDEPPPKATPAAPSRVRELPTSVIPPLWYNYYCVSKNPRYVTLQNTESERLFFMRENGDTPQDKKRFGVQQPRVPKTRAAVPKISIVRRGGVGVAEWSTLREGSAPPPAPKRRGTNVTDSLAMKDKSNGVCNGESSSASDSEPSGVLDKHSTSVRVVDSLRYIRGGSVSGANTDRRAPSGSSKETPGDRIDPEESDDEDDALYSSEDGATIRIERKLETGSSRTDTSSTPTDEHRAFEGGVVLPNGVLASDFSSAEASLNDARECREGFNGAEQLMRSNDTVSHVIHVHHGKILRSVDQSQTRDSAGETSFVDSSRGVTAMKTIAPSLTVTSTSQAYGSGDRTRNEISRSSIGMHGSSCGLGDLSLPSTRRCGEGSDLPDGGVVGFSSAPASRAMCSDSVTVELQHEENGDLYSDPGGGRIAGVDSSLFHTSVSSTKGGSLSNNLPNPLLALNKRLGPHMRTYSSPF
Protein: Myoneurin (Zinc finger and BTB domain-containing protein 31) (Q9NPC7)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000269|PubMed:14694499}.
Interaction partners:
- Leucine-rich repeat-containing protein 34
- Serine/threonine-protein kinase RIO2
- Leucine-rich repeat and IQ domain-containing protein 4
- Actin-related protein T3
Sequence:
MQYSHHCEHLLERLNKQREAGFLCDCTIVIGEFQFKAHRNVLASFSEYFGAIYRSTSENNVFLDQSQVKADGFQKLLEFIYTGTLNLDSWNVKEIHQAADYLKVEEVVTKCKIKMEDFAFIANPSSTEISSITGNIELNQQTCLLTLRDYNNREKSEVSTDLIQANPKQGALAKKSSQTKKKKKAFNSPKTGQNKTVQYPSDILENASVELFLDANKLPTPVVEQVAQINDNSELELTSVVENTFPAQDIVHTVTVKRKRGKSQPNCALKEHSMSNIASVKSPYEAENSGEELDQRYSKAKPMCNTCGKVFSEASSLRRHMRIHKGVKPYVCHLCGKAFTQCNQLKTHVRTHTGEKPYKCELCDKGFAQKCQLVFHSRMHHGEEKPYKCDVCNLQFATSSNLKIHARKHSGEKPYVCDRCGQRFAQASTLTYHVRRHTGEKPYVCDTCGKAFAVSSSLITHSRKHTGEKPYICGICGKSFISSGELNKHFRSHTGERPFICELCGNSYTDIKNLKKHKTKVHSGADKTLDSSAEDHTLSEQDSIQKSPLSETMDVKPSDMTLPLALPLGTEDHHMLLPVTDTQSPTSDTLLRSTVNGYSEPQLIFLQQLY
Protein: V(D)J recombination-activating protein 1 (EC 2.3.2.27) (EC 3.1.-.-) (Q68AY0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU366024}.
Interaction partners:
Sequence:
VKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRVTVEHGSQNVKIFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELLLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDATRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKNPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYR
Protein: UPF0381 protein YfcZ (P0AD33)
Organism: Escherichia coli (strain K12)
Interaction partners:
- NADP-dependent 3-hydroxy acid dehydrogenase YdfG
Sequence:
MSKCSADETPVCCCMDVGTIMDNSDCTASYSRVFANRAEAEQTLAALTEKARSVESEPCKITPTFTEESDGVRLDIDFTFACEAEMLIFQLGLR
Protein: G-protein coupled receptor (Q6WNX8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MLQGVAITIANDSNDDGLNQSFMAHVSPSPNQSPSIGVGIGIASSTMANPSESPEMLLLKNDKFLTHVAHLLNITTENLSNLLGSTNGTNASTMAADSPVDESLTLRTALTVCYALIFVAGVLGNLITCIVISRNNFMHTATNFYLFNLAVSDLILLVSGIPQELYNLWYPDMYPFTDAMCIMGSVLSEMAANATVLTITAFTVERYIAICHPFRQHTMSKLSRAIKFIFAIWLAAFLLALPQAMQFSVVYQNEGYSCTMENDFYAHVFAVSGFIFFGGPMTAICVLYVLIGVKLKRSRLLQSLPRRTFDANRGLNAQGRVIRMLVAVAVAFFLCWAPFHAQRLMAVYGLNLINIGISRDAFNDYFRILDYTSGVLYFLSTCINPLLYNIMSHKFREAFKITLTRQFGLARNHHHQQSQHHQHNYSALLRQNGSMRLQPASCSVNNNALEPYGSYRVVQFRCRDANHQLSLQDSIRTTTTTTTINSNSMAAGNGVGGGAGGGGRRLRKQELYGPVPGTAVPHRMLQAQVSQLSSLGDANSLLEAEVVDRHYASGRAKRALLATKSGALLVTPPQSGDPSEVSQPATRLKLTRVISRRDEVANASTPPFCGSHSLPDPETCQSASVAGRSSRKFPWRKRRQKTEDPSSEGLTYGSPKSQ
Protein: Splicing factor ESS-2 homolog (DiGeorge syndrome critical region 13) (DiGeorge syndrome critical region 14) (DiGeorge syndrome protein H) (DGS-H) (Protein ES2) (Q96DF8)
Organism: Homo sapiens (Human)
Function: May be involved in pre-mRNA splicing.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P34420}.
Interaction partners:
- Integral membrane protein DGCR2/IDD
- Glutamine amidotransferase-like class 1 domain-containing protein 3
- Transcription factor SOX-2
- Protein FRA10AC1
- Estrogen receptor
- Tricarboxylate transport protein, mitochondrial
- Protein HIRA
- Polycomb protein SUZ12
- Ubiquitin recognition factor in ER-associated degradation protein 1
- Tetratricopeptide repeat protein 14
Sequence:
METPGASASSLLLPAASRPPRKREAGEAGAATSKQRVLDEEEYIEGLQTVIQRDFFPDVEKLQAQKEYLEAEENGDLERMRQIAIKFGSALGKMSREPPPPYVTPATFETPEVHAGTGVVGNKPRPRGRGLEDGEAGEEEEKEPLPSLDVFLSRYTSEDNASFQEIMEVAKERSRARHAWLYQAEEEFEKRQKDNLELPSAEHQAIESSQASVETWKYKAKNSLMYYPEGVPDEEQLFKKPRQVVHKNTRFLRDPFSQALSRCQLQQAAALNAQHKQGKVGPDGKELIPQESPRVGGFGFVATPSPAPGVNESPMMTWGEVENTPLRVEGSETPYVDRTPGPAFKILEPGRRERLGLKMANEAAAKNRAKKQEALRRVTENLASLTPKGLSPAMSPALQRLVSRTASKYTDRALRASYTPSPARSTHLKTPASGLQTPTSTPAPGSATRTPLTQDPASITDNLLQLPARRKASDFF
Protein: Ankyrin repeat and SAM domain-containing protein 1A (Odin) (Q92625)
Organism: Homo sapiens (Human)
Function: Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control cell migration and neurite retraction (By similarity).
Subcellular location: Cytoplasm. Cell projection {ECO:0000250}. Note=Cytoplasmic before and after growth factor treatment.
Interaction partners:
- Ras and Rab interactor 1
- Disabled homolog 2-interacting protein
- Epidermal growth factor receptor
Sequence:
MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGGGGGGSGGGGGGLGSSSHPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTVRELPSQKSQQIAALIEDHMTGKRSTKEVDKTPPPQPPLISSMDSISQKSQGDVEKAVTELIIDFDANAEEEGPYEALYNAISCHSLDSMASGRSSDQDSTNKEAEAAGVKPAGVRPRERPPPPAKPPPDEEEEDHIDKKYFPLTASEVLSMRPRIHGSAAREEDEHPYELLLTAETKKVVLVDGKTKDHRRSSSSRSQDSAEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQLLCTAGQSHPDGSPQQGACHKASMQLEETGVHAPGASQPSALDQSKRVGYLTGLPTTNSRSHPETLTHTASPHPGGAEEGDRSGARSRAPPTSKPKAELKLSRSLSKSDSDLLTCSPTEDATMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQERQKISGLRTLEQSVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSLPKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLLGHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGDTGRRRHDSLHDPAAPSRAERFRIQEEHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSRATGASAAEMIETKSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVSWVVDPKPDSKRSLSTN
Protein: Ubiquitin receptor RAD23c (AtRAD23c) (Putative DNA repair protein RAD23-3) (RAD23-like protein 3) (AtRAD23-3) (Q84L31)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in nucleotide excision repair (By similarity). Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains. Acts as a ubiquitin receptor that associates with the 26S proteasomal docking subunit RPN10 for the indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP).
Subcellular location: Nucleus {ECO:0000269|PubMed:20086187}. Cytoplasm {ECO:0000269|PubMed:20086187}.
Interaction partners:
- 26S proteasome non-ATPase regulatory subunit 4 homolog
- DNA repair protein RAD4
- Peptide-N
- Probable ubiquitin conjugation factor E4
- 26S proteasome regulatory subunit RPN13
- Ubiquitin domain-containing protein DSK2b
- Protein DNA-DAMAGE INDUCIBLE 1
- Protein NBR1 homolog
- Calcium-binding protein CML19
- Ubiquitin domain-containing protein DSK2a
Sequence:
MKIFVKTLKGTHFEIEVKPEDSVVDVKKNIESVQGADVYPAAKQMLIHQGKVLKDETTIEENKVAENSFIVIMMNKSKPASAAASSASAGTSQAKSIPPSTSQPSISPQTPASVSAPVAPAPTRPPPPAPTPTPAPVAATETVTTPIPEPVPATISSSTPAPDSAPVGSQGDVYGQAASNLAAGSNLESTIQQILDMGGGTWDRETVVLALRAAFNNPERAVEYLYTGIPEQAEVPPVARPPASAGQPANPPAQTQQPAAAPASGPNANPLDLFPQGLPNVGGNPGAGTLDFLRNSQQFQALRAMVQANPQVLQPMLQELGKQNPNLMRLIQDHQADFLRLINEPVEGGGESGNLLGQMAAGMPQPQAIQVTHEEREAIERLEAMGFERALVLEVFFACNKNEELAANYLLDHMHEFEE