wanglab/gogpt-training-data huggingface dataset:
Protein: 1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] chlorinase (EC 1.14.19.56) (FADH2-dependent halogenase PltA) (Q4KCZ0)
Organism: Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Function: Involved in the biosynthesis of the antibiotic pyoluteorin. Catalyzes the dichlorination of the pyrrole ring of pyrrolyl-S-PltL, generating the 5-chloropyrrolyl-S-PltL intermediate and then the 4,5-dichloropyrrolyl-S-PltL product.
Interaction partners:
- Peptidyl carrier protein PltL
- Polyketide synthase PltB
- Polyketide synthase PltC
- Putative halogenase PltD
- Putative acyl carrier protein
- L-proline--[L-prolyl-carrier protein] ligase
- L-prolyl-[peptidyl-carrier protein] dehydrogenase
- Lipid A biosynthesis
- Thioesterase PltG
- AMP-binding domain protein
Sequence:
MSDHDYDVVIIGGGPAGSTMASYLAKAGVKCAVFEKELFEREHVGESLVPATTPVLLEIGVMEKIEKANFPKKFGAAWTSADSGPEDKMGFQGLDHDFRSAEILFNERKQEGVDRDFTFHVDRGKFDRILLEHAGSLGAKVFQGVEIADVEFLSPGNVIVNAKLGKRSVEIKAKMVVDASGRNVLLGRRLGLREKDPVFNQFAIHSWFDNFDRKSATQSPDKVDYIFIHFLPMTNTWVWQIPITETITSVGVVTQKQNYTNSDLTYEEFFWEAVKTRENLHDALKASEQVRPFKKEADYSYGMKEVCGDSFVLIGDAARFVDPIFSSGVSVALNSARIASGDIIEAVKNNDFSKSSFTHYEGMIRNGIKNWYEFITLYYRLNILFTAFVQDPRYRLDILQLLQGDVYSGKRLEVLDKMREIIAAVESDPEHLWHKYLGDMQVPTAKPAF
Protein: Transmembrane protein (Q54TF3)
Organism: Dictyostelium discoideum (Social amoeba)
Interaction partners:
- EGF-like domain-containing protein
- EGF-like domain-containing protein
- GRAM domain-containing protein
- von Willebrand factor A domain-containing protein DDB_G0292028
- Transmembrane protein
- DUF7788 domain-containing protein
- Purple acid phosphatase N-terminal domain-containing protein
- EGF-like domain-containing protein
- EGF-like domain-containing protein
- C2 domain-containing protein DDB_G0290753
Sequence:
MKIFNLLVVLLSIVNISLGQITFQKYVDFNGYNQPNCGASTEPCKSIEYVINQIKSYSYEQFSIEILLGRGTHHSLTPTNLYGLNITIGAANPGESVQLLASSSLGTAQFTVDHSNYYDIIPTNIVFRDLTVTCDLSYTWNGLLLQSNINSYQNLFLNVKTENVIFSCANSDFSYFSVSNNYNSYDQLAQKKNQLPYGSESYSSSESNSESNSESYSSEFNSESSGSYSSESSGSYSSESSGSESSGSYSSESYSSESYSSESYSPESYSSESSYNSENDNNNYYQDLYMEVVDQVFGVNSYPYDNINISFAFNNCQFNYQMNNQYPVVLNANFDFTIDLKITNSIFNTNYIFNSAPLVQLYGGSLTMDNVSIVSLSFVSNGTNSLFYLVNARVSFNKVSISGSISGPFIKAVNCIVTANQFNIISEKNYEISYHLITLTESFAYFENSTIVLSVKSDVKNYFSSNIAIFNPVNSELYLFSNRISSNGSSIVYSQSSDVSANNNQFQYAPYSVNSYQLVQCDYGISRFYGDYQFTSYSDSCQAKINVLSFWNTNANLLEIIISYLSGVLSIVLVFVTMFTISAIGKCCRRKRKAIQKLKKEKEEEAAEAAKSLLSINDSA
Protein: Rab11 interacting protein, isoform C (X2JEA7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004308}. Recycling endosome {ECO:0000256|ARBA:ARBA00004172}.
Interaction partners:
Sequence:
MWSPTHCSVTVQRARGLLTKGKNGTNNCFVTIALGKEKYQTSVKDKAETSVNWNEECELKIPDQGNRAELTLTCLHRNNLGIDEFLGQATLPLNEMDVYDRPRAKWFKLESKPGKEKKNKERGELEVRIAFVVKSGSLTDLSKKDKHKSSIGQLASSVGGSLLSIGNGEKRRGIKKLAGSLSSKLHIRSKKKNQEAGADDSSSFGGSFASLGTPNSSNGRGQNGGSGRRRGGQRAGEADPGVISEDEDEFVFDNLSHKSSGSSLNIQRIGLQPPPVGTPNFTPRHPSPLLNNGVSGVGSGSAKDKYNNDNDSNSPSPKSTERIIIGHEKSGSHADRRSEISAQLAKKYEGKSREELMLIANGMENEALLQRQRVKELEDYLDNLLLRVMETHPKILQNPYSRTTSAKSYKNYINMNDFLK
Protein: Gpt1p (A0A1D8PDH1)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MNSGIHTPHEIHPVVSQVHVDDMGIASILSNKNITINVDHVIDSDEAMLLAIGYRQELRREFSLWSIFAVSFSVLGLLPSIAACFDYQQLVVGMSPLPWLIAMIFITSVAYSMAEIASAFPCSAGTPYAVSQLAPKKYASFLTWFTCWTNWSCQITAAPSVSYSCACMMLALHSFTDPSFVASNAQIFGLTTGIQVLCAFMACFPTKWVARFSSAGTTCNIVFLVVVFVMILGGNKRDQIKEGISKFNSNSTAWGLDNQAEWPTGLSFLISFMGVIWAMSGYDSPFHLAEECSNAAVAAPRAIVLTSTVGGLIGFMFMIAIAYTLVDLNQISADPEGLGQPFVTYLTQIMDKNLVIGATALTIISSFFMAQNCLLASSRVTYAYARDGLFPLSGIWKKVSPKTQTPINAVIMNFIVEELLLLLIFGGDVSIGSIFSIGALAGFISFTMPTLLKITYARKTFQPGPWNLGKWSEPIGWVSVAFVGLMVPILCFPTVKGADLTPTEMNWTCLVYFGLILLTTIWFVVDARRWYVGPRTNISEEDIVYGEKTEDEGDEIPDVIDGQKVSISSTEKRYQ
Protein: RNA editing complex protein MP46 (Q86MV9)
Organism: Trypanosoma brucei
Interaction partners:
Sequence:
MLRVENLRRSMTRLARHSLIRAVPFSPLSVGSSTDQTFGAPTRTPFRSHTCLLCDVSYESWGDHAESTTHIARHAICRTFVSPERHNAVMQQLWKHIRLDFGYVDEVTHKKEDRRRMRLASTMRHLQEKGVLHHSLPRVTVDAQSEVSLTVESDSFVNYMFLGESFARQETLDRVARLMPRAEALELSSIISFVLSKRRLAHFFDILDMRKMVLNGDSSDDKASADGGVPPTIPRLQQDGKAVILFSCLGELQMFSRRDRSHSVATRSAAEQLVLNVLGTHVMENIIGELVHEALQTVVEEGTAVWREHCGELKHKLFEGTKAVSPPIATTPNPVSNSGGPEVTADVNDQMWVDLCRLYVLDKNGSVPQLQPTVKRHSWHDVARALTLELTVPNPVNKSAVFAAAAPRLATKKK
Protein: AT3G03270 protein (Adenine nucleotide alpha hydrolases-like superfamily protein) (Q8LFK2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- AT4g27450/F27G19_50
- At1g01170)
- AT3G11930 protein
- Tetratricopeptide repeat protein SKI3
- Aspartate aminotransferase, cytoplasmic isozyme 1
- Arginyl-tRNA--protein transferase 1
Sequence:
MGKARTVGVGMDYSPTSKLALRWAAENLLEDGDTVILIHVQPQNADHTRKILFEETGSPLIPLEEFREVNLSKQYGLAYDPEVLDVLDTLSRAKKVKVVAKVYWGDPREKLCDAVENLKLDSIVLGSRGLGSLKRPNHNGFMIIMFDHSLVGLVSLDHDQSGLINMAEMGSSKSICWIRRNQERDSRWSFSDLLLDDHPLD
Protein: Potassium uptake protein TrkA, putative (Q72F06)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- Potassium uptake protein, TrkH family
- Heptosyltransferase family protein
Sequence:
MATPKLEIGVIGLGKFGLQVSRTLVELGHSVVGIDSTEGRIRQAQDILSQVYQGNAADPAVLQQLRFQDLDCVIVSVGNSMETSLLVTLNLQEIGVRKIWVKAVSTEHKKVLTRLGVDHVILPEHDVATHLAHRLVNPGMLDLLPLGGGGQILLQELTVDKWAGRTLLDLRLANEHGVMVVAVKPAAFREYRFVPAAHEVLQQGDKLVVIGRHEDVLRLEP
Protein: Protein ATP1B4 (X,K-ATPase subunit beta-m) (X/potassium-transporting ATPase subunit beta-m) (Q9R193)
Organism: Rattus norvegicus (Rat)
Function: May act as a transcriptional coregulator during muscle development through its interaction with SNW1. Has lost its ancestral function as a Na,K-ATPase beta-subunit (By similarity).
Subcellular location: Nucleus inner membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Note=Detected in nuclear envelops. {ECO:0000250}.
Interaction partners:
- Sodium/potassium-transporting ATPase subunit gamma
- Sodium/potassium-transporting ATPase subunit alpha-2
- Sodium/potassium-transporting ATPase subunit alpha-1
- Sodium/potassium-transporting ATPase subunit alpha-4
- Sodium/potassium-transporting ATPase subunit alpha-3
- SNW domain-containing protein 1
- Sodium/potassium-transporting ATPase subunit beta-2
- Sodium/potassium-transporting ATPase subunit beta-3
- Sodium/potassium-transporting ATPase subunit beta-1
- Phospholemman
Sequence:
MRRQLRSRRAPAFPYGYRYRLDDQDEMNHNYLADEEEEAEEEAQVMMVPGLEEEEEEEEGKEEEEEREEEEGQGQSTGNAWWRKLQIVNEYLWDPEKRMSLARTGQSRSLILVIYFFFYASLAAVITLFIYMLFLAISPYMPTFTEQVKPPGVMIRPFAHSLNFNFNVSEPETWQRYVISLNGFLQGYNDSLQEEMNIDCPPGQYFIQDGDEDEDKKACQFKRSFLKNCSGLEDPTFGYSTGQPCILLKMNRIVGFRPEFGDPVKVSCKVQKGDENDIRSINYYPESASFDLRYYPYYGKLTHVNYTSPLVAMHFTDVVKNQEVPVQCQLKGKGIVNDVINDRFVGRIIFTLNIET
Protein: CCDC81 HU domain-containing protein (Q383J9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MEPSKTSTRRNPDQCYACYSEIANIVAQMGGLYCHQSRNAGPQLLCRIWRTLCESVEETLVRKRSCIIPDFLHASIKVQRVSPFDGEINLYKPQMVLLPDFLSKFHVQNVLTFRDAHYHATVPNIISFDEIAAIVGTDRHIVKAAVSESVREIGKYLDRNKCAVLSIDVGVAFLEFRGREYRIKWADTFLERLKREVGPRSFVEPYIPPTMAPDARGCRFQSECLTKESLHGSLNDTLQRESRTQVVEMCGSQNKQFTLSPS
Protein: C-C motif chemokine 3-like 1 (G0/G1 switch regulatory protein 19-2) (LD78-beta(1-70)) (PAT 464.2) (Small-inducible cytokine A3-like 1) (Tonsillar lymphocyte LD78 beta protein) [Cleaved into: LD78-beta(3-70); LD78-beta(5-70)] (P16619)
Organism: Homo sapiens (Human)
Function: Chemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5.
Subcellular location: Secreted.
Interaction partners:
- C-C chemokine receptor type 5
- C-C chemokine receptor type 1
- C-C chemokine receptor type 3
- C-C motif chemokine 3
- C-C motif chemokine ligand 4 like 2.
- C-C chemokine receptor type 2
- Tumor necrosis factor
- Atypical chemokine receptor 2
- C-C chemokine receptor type 7
- CX3C chemokine receptor 1
Sequence:
MQVSTAALAVLLCTMALCNQVLSAPLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSKPSVIFLTKRGRQVCADPSEEWVQKYVSDLELSA
Protein: Transmembrane protease serine 13 (EC 3.4.21.-) (Membrane-type mosaic serine protease) (Mosaic serine protease) (Q9BYE2)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane {ECO:0000269|PubMed:28710277, ECO:0000269|PubMed:34562451, ECO:0000269|PubMed:35796294}; Single-pass type II membrane protein {ECO:0000255}. Secreted {ECO:0000269|PubMed:35796294}. Cytoplasm {ECO:0000269|PubMed:28710277}. Note=The non-phosphorylated, inactive full length protein localizes intracellularly (PubMed:28710277). N-glycosylation and phosphorylation is required for trafficking to the cell surface (PubMed:28710277, PubMed:34562451, PubMed:35796294). Interaction with SPINT1/HAI-1 and SPINT2/HAI-2 facilitate its translocation to the cell surface (PubMed:34562451, PubMed:35796294). Proteolytic cleavage is required for secretion (PubMed:35796294). {ECO:0000269|PubMed:28710277, ECO:0000269|PubMed:34562451, ECO:0000269|PubMed:35796294}.
Interaction partners:
Sequence:
MERDSHGNASPARTPSAGASPAQASPAGTPPGRASPAQASPAQASPAGTPPGRASPAQASPAGTPPGRASPGRASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVYLVRATPVGAVPIRSSPARSAPATRATRESPGTSLPKFTWREGQKQLPLIGCVLLLIALVVSLIILFQFWQGHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMEVRSLQQDTAPSRLGTSSGGDPGGAPRL
Protein: Glial fibrillary acidic protein (GFAP) (P47819)
Organism: Rattus norvegicus (Rat)
Function: GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P14136}. Note=Associated with intermediate filaments. {ECO:0000250|UniProtKB:P14136}.
Interaction partners:
- Elongation factor 1-alpha 1
- RNA binding protein fox-1 homolog 3
- Allograft inflammatory factor 1
- Oligodendrocyte transcription factor 2
- Myelin basic protein
- Synaptophysin
- Protein S100-B
- Neuronal migration protein doublecortin
- Macrosialin
- Peroxidasin
Sequence:
MERRRITSARRSYASSETMVRGHGPTRHLGTIPRLSLSRMTPPLPARVDFSLAGALNAGFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAELRELRLRLDQLTTNSARLEVERDNLTQDLGTLRQKLQDETNLRLEAENNLAVYRQEADEATLARVDLERKVESLEEEIQFLRKIHEEEVRELQEQLAQQQVHVEMDVAKPDLTAALREIRTQYEAVATSNMQETEEWYRSKFADLTDVASRNAELLRQAKHEANDYRRQLQALTCDLESLRGTNESLERQMREQEERHARESASYQEALARLEEEGQSLKEEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM
Protein: Transcription factor TFIIIB component B'' (TFIIIB90) (P46678)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: General activator of RNA polymerase III transcription.
Subcellular location: Nucleus.
Interaction partners:
- Transcription factor IIIB 70 kDa subunit
- TATA-box-binding protein
- Transcription factor tau 131 kDa subunit
- Transcription factor tau 60 kDa subunit
- Transcription factor tau 138 kDa subunit
- DNA-directed RNA polymerase III subunit RPC6
- DNA-directed RNA polymerase III subunit RPC5
- Transcription factor tau 95 kDa subunit
- DNA-directed RNA polymerase III subunit RPC1
- DNA-directed RNA polymerase III subunit RPC9
Sequence:
MSSIVNKSGTRFAPKVRQRRAATGGTPTPKPRTPQLFIPESKEIEEDNSDNDKGVDENETAIVEKPSLVGERSLEGFTLTGTNGHDNEIGDEGPIDASTQNPKADVIEDNVTLKPAPLQTHRDQKVPRSSRLASLSKDNESRPSFKPSFLDSSSNSNGTARRLSTISNKLPKKIRLGSITENDMNLKTFKRHRVLGKPSSAKKPAGAHRISIVSKISPPTAMTDSLDRNEFSSETSTSREADENENYVISKVKDIPKKVRDGESAKYFIDEENFTMAELCKPNFPIGQISENFEKSKMAKKAKLEKRRHLRELRMRARQEFKPLHSLTKEEQEEEEEKRKEERDKLLNADIPESDRKAHTAIQLKLNPDGTMAIDEETMVVDRHKNASIENEYKEKVDENPFANLYNYGSYGRGSYTDPWTVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRSKLPPNFDEYCCEIKKNIGTVADFNEKLIELQNEHKHHMKEIEEAKNTAKEEDQTAQRLNDANLNKKGSGGIMTNDLKVYRKTEVVLGTIDDLKRKKLKERNNDDNEDNEGSEEEPEIDQ
Protein: Large ribosomal subunit protein uL15 (60S ribosomal protein L27a) (L29) (O15883)
Organism: Trypanosoma brucei brucei
Interaction partners:
Sequence:
MPTRFKKTRHQRGSTFCGYGRVGKHRKHPSGRGNAGGEHHHRINFRKYHPGYFGKCGMNHYHKKKNTTWKPTINLDNLTKLMAKDEAMKAKKGEVLPVIDLLANGYSKLLGNGHLQAPCIVKARWVSKLADKKIRKAGGAVVLQA
Protein: 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (EC 1.14.14.139) (7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase) (CYPVIIIB1) (Cytochrome P450 8B1) (Sterol 12-alpha-hydroxylase) (Q9UNU6)
Organism: Homo sapiens (Human)
Function: A cytochrome P450 monooxygenase involved in primary bile acid biosynthesis. Catalyzes the 12alpha-hydroxylation of 7alpha-hydroxy-4-cholesten-3-one, an intermediate metabolite in cholic acid biosynthesis. Controls biliary balance of cholic acid and chenodeoxycholic acid, ultimately regulating the intestinal absorption of dietary lipids (By similarity). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH--hemoprotein reductase) (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O02766}; Single-pass membrane protein {ECO:0000255}. Microsome membrane {ECO:0000250|UniProtKB:O02766}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- 3 beta-hydroxysteroid dehydrogenase type 7
- Aldo-keto reductase family 1 member D1
- Nuclear receptor subfamily 0 group B member 2
- Sterol 26-hydroxylase, mitochondrial
- Aldo-keto reductase family 1 member C4
- Nuclear receptor subfamily 5 group A member 2
- Bile acid receptor
- Beta-klotho
- Bile salt export pump
- Hepatic sodium/bile acid cotransporter
Sequence:
MVLWGPVLGALLVVIAGYLCLPGMLRQRRPWEPPLDKGTVPWLGHAMAFRKNMFEFLKRMRTKHGDVFTVQLGGQYFTFVMDPLSFGSILKDTQRKLDFGQYAKKLVLKVFGYRSVQGDHEMIHSASTKHLRGDGLKDLNETMLDSLSFVMLTSKGWSLDASCWHEDSLFRFCYYILFTAGYLSLFGYTKDKEQDLLQAGELFMEFRKFDLLFPRFVYSLLWPREWLEVGRLQRLFHKMLSVSHSQEKEGISNWLGNMLQFLREQGVPSAMQDKFNFMMLWASQGNTGPTSFWALLYLLKHPEAIRAVREEATQVLGEARLETKQSFAFKLGALQHTPVLDSVVEETLRLRAAPTLLRLVHEDYTLKMSSGQEYLFRHGDILALFPYLSVHMDPDIHPEPTVFKYDRFLNPNGSRKVDFFKTGKKIHHYTMPWGSGVSICPGRFFALSEVKLFILLMVTHFDLELVDPDTPLPHVDPQRWGFGTMQPSHDVRFRYRLHPTE
Protein: receptor protein-tyrosine kinase (EC 2.7.10.1) (A0A0G2K2H0)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MGRVPLAWCVALCCWGCAAPKDTQTEADSPFVGNPGNITGARGLTGTLRCELQVQGEPPEVMWLRDGQILELADNTQTQVPLGEDWQDEWKVVSQLRISALQLSDAGEYQCMVHLEGRTFVSQPGFVGLEGLPYFLEEPEDKAVPANTPFNLSCQAQGPPEPVTLLWLQDAVPLAPVAGYSFQHSLQAPGLNKTSSFSCEAHNAKGVTTSRTATITVLPQRPHNLHVVSRHPTELEVAWIPSLSGIYPLTHCTLQAVLSDDGVGVWLGESDPPEEPLTVQVSVPPHQLRLEKLLPHTPYHIRVSCTSSQGPSPWTHWLPVETTEGVPLGPPENVSAMRNGSQALVRWQEPREPLQGTLLGYRLAYRGQDTPEVLMDIGLTREVTLELRGDRPVANLTVSVAAYTSAGDGPWSLPVPLEPWRPVSEPPPPAFSWPWWYVLLGALVAAACVLILTLFLVHRRKKETRYGEVFEPTVERGELVVRYRARKSYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGKTLGEGEFGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRLIGVCFQGSDREGFPEPVVILPFMKHGDLHSFLLYSRLGDQPVFLPTQMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLRQGNRLKQPLDCLDGLYALMSRCWELNPRDRPSFAELREDLENTLKALPPAQEPDEILYVNMDEGGSHLEPRGAAGGADPPTQPDPKDSCSCLTEADVHSAGRYVLCPSTAPGPTLSADRGCPAPPGQEDGA
Protein: Fasciclin-like arabinogalactan protein 17 (Q66GR0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be a cell surface adhesion protein.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Fasciclin-like arabinogalactan protein 11
- Fasciclin-like arabinogalactan protein 9
- Classical arabinogalactan protein 5
- Fasciclin-like arabinogalactan protein 1
- COBRA-like protein 1
- Fasciclin-like arabinogalactan protein 3
- Cytochrome P450 71B34
- Fasciclin-like arabinogalactan protein 4
- Classical arabinogalactan protein 4
- Fasciclin-like arabinogalactan protein 10
Sequence:
MDRRIYGGSAVIHLFLFFSVLIFSAASALSKNQSPSSGSGQINSNSVLVALLDSRYTELAELVEKALLLQTLEDAVGRHNITIFAPRNEALERDLDPEFKRFLLEPGNLKSLQTLLMFHIIPNRVGSNQWPSEESGRVKHHTLGNDQVRLSNGQGKKMVDLAEIIRPDDLTRPDGLIHGIERLLIPRSVQEDFNRRRSLQSISAVLPEGAPEVDPRTNRLKKPAAPVPAGSPPALPIQSAMAPGPSLAPAPAPGPGGKQHHFDGEAQVKDFIHTLLHYGGYNEMADILVNLTSLATEMGRLVSEGYVLTVLAPNDEAMAKLTTDQLSEPGAPEQIVYYHIIPEYQTEESMYNSVRRFGKVKFDTLRFPHKVAAKEADGSVKFGDGEKSAYLFDPDIYTDGRISVQGIDGVLFPQEEEVVESVKKPVKKIVQPRRGKLLEVACSMLGAFGKDTYLSKCR
Protein: Mesogenin-1 (Paraxial mesoderm-specific mesogenin1) (pMesogenin1) (pMsgn1) (Q9JK54)
Organism: Mus musculus (Mouse)
Function: Involved in specifying the paraxial, but not dorsal, mesoderm. May regulate the expression of T-box transcription factors required for mesoderm formation and differentiation.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}.
Interaction partners:
- T-box transcription factor TBX6
Sequence:
MDNLGETFLSLEDGLDSSDTAGLLASWDWKSRARPLELVQESPTQSLSPAPSLESYSEVALPCGHSGASTGGSDGYGSHEAAGLVELDYSMLAFQPPYLHTAGGLKGQKGSKVKMSVQRRRKASEREKLRMRTLADALHTLRNYLPPVYSQRGQPLTKIQTLKYTIKYIGELTDLLNSSGREPRPQSV
Protein: Fatty acid-binding protein homolog 6 (O01812)
Organism: Caenorhabditis elegans
Interaction partners:
- Fatty acid-binding protein homolog 4
Sequence:
MSQEFVGRWKLIHSENFEEYMKEVGVGLITRKAAANLKPTLEIKVEGDLWYSNQYSTFKNTTLSFKLGQEFDETTPDGRTVKSVVNFENGKFIHIQKKIKDSDKESIITRWLEGDKLITTLESGSVVSRREYVRE
Protein: Outer dense fiber protein 2 (Cenexin) (Outer dense fiber of sperm tails protein 2) (Q5BJF6)
Organism: Homo sapiens (Human)
Function: Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:14654843, ECO:0000269|PubMed:16966375}. Cell projection, cilium {ECO:0000250|UniProtKB:A3KGV1}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:23400999}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250|UniProtKB:A3KGV1}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:A3KGV1}. Note=Localized at the microtubule organizing centers in interphase and spindle poles in mitosis. Localized at the distal/subdistal appendages of mother centrioles. {ECO:0000250|UniProtKB:A3KGV1}.
Interaction partners:
- Centriolin
- Ninein
- Centrosomal protein of 128 kDa
- Serine/threonine-protein kinase PLK1
- Outer dense fiber protein 1
- Centrosomal protein of 170 kDa
- Coiled-coil domain-containing protein 120
- Ras-related protein Rab-8A
- Centrosomal protein of 83 kDa
- Coiled-coil domain-containing protein 68
Sequence:
MSASSSGGSPRFPSCGKNGVTSLTQKKVLRAPCGAPSVTVTKSHKRGMKGDTVNVRRSVRVKTKVPWMPPGKSSARPVGCKWENPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERMKEEKDFTILQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQNIEFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLESAIEDARRQVEQTKEHALSKERAAQNKILDLETQLSRTKTELSQLRRSRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKSSYANVFGDGPYSTFLTSSPIRSRSPPA
Protein: Elongator complex protein 6 (Angiotonin-transactivated protein 1) (Protein TMEM103) (Q0PNE2)
Organism: Homo sapiens (Human)
Function: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. Involved in cell migration (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:22645656}. Nucleus {ECO:0000269|PubMed:22645656}. Note=Concentrates in the nucleus upon insulin stimulation. {ECO:0000269|PubMed:22645656}.
Interaction partners:
- Elongator complex protein 5
- Elongator complex protein 4
- Elongator complex protein 3
- Elongator complex protein 2
- Elongator complex protein 1
- Peroxisomal sarcosine oxidase
- Cholesterol transporter ABCA5
- Phospholipid-transporting ATPase ABCA7
- ATP-binding cassette sub-family A member 2
- ATP synthase F
Sequence:
MFVELNNLLNTTPDRAEQGKLTLLCDAKTDGSFLVHHFLSFYLKANCKVCFVALIQSFSHYSIVGQKLGVSLTMARERGQLVFLEGLKSAVDVVFQAQKEPHPLQFLREANAGNLKPLFEFVREALKPVDSGEARWTYPVLLVDDLSVLLSLGMGAVAVLDFIHYCRATVCWELKGNMVVLVHDSGDAEDEENDILLNGLSHQSHLILRAEGLATGFCRDVHGQLRILWRRPSQPAVHRDQSFTYQYKIQDKSVSFFAKGMSPAVL
Protein: Uncharacterized protein YNL208W (P40159)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14576278}.
Interaction partners:
- Uncharacterized protein YBL086C
Sequence:
MSANEFYSSGQQGQYNQQNNQERTGAPNNGQYGADNGNPNGERGLFSTIVGGSAGAYAGSKVSNNHSKLSGVLGAIGGAFLANKISDERKEHKQQEQYGNSNFGGAPQGGHNNHHRQDNNNNNGGFGGPGGPGGQGFGRQGPQGFGGPGPQEFGGPGGQGFGGPNPQEFGGPGGQGFGGPNPQEFGGQGRQGFNGGSRW
Protein: Forkhead transcription factor fkh-6 (Q10924)
Organism: Caenorhabditis elegans
Function: Probable transcription factor. Binds to the DNA sequence motif 5'-[TA]TGTT[TG]T[TG][ATG]TT-3'. Regulates sexual dimorphism in the gonad, promoting male gonadal cell fates in chromosomally (XO) male animals, yet plays a role in gonadogenesis in both sexes; probably acts downstream of terminal regulator of sex determination tra-1, to control early gonadogenesis. Positively modulates expression of homeobox protein egl-5, probably acting indirectly, during early gonadal development.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00089}.
Interaction partners:
- Transmembrane protein
- Putative forkhead-related transcription factor fkh-5
- Zinc finger protein ehn-3
- C2H2-type domain-containing protein
- Zinc finger protein ztf-16
- Nuclear hormone receptor family member nhr-89
- GON-4-like protein
Sequence:
MTRHQTHLPFHIVQEGNSIDKPPYSYVALIAMAIDASPDKRMTLNQIYKFIEAKFPYYRDADAKRKQGWQNSIRHNLSLNDCFVKKARDGQSCANDRKGNYWQMVADNAPQFDNGNFKRRRVKRLGIGKMGYANTTETTETGTILQQQLPFFNGLKWPQNIQTMDPFQFFKFQYPNSITDSANTSQINNSSSSSSSFDTSIYTSAFPIPTSHFDTNLVAPSQPPPVVSDVEVVPSDTVKEEVLVDMKPLIPGISSTTFLTSLQMTDPRSIEQQQLLSTASNMYPNAFMPPYTNWSCQPTTTFTGLSFDDPSLYGYGQQFPASS
Protein: NmrA-like family domain-containing protein 1 (A0A384P622)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVDKKLVVVFGGTGAQGGSVARTLLEDGTFKVRVVTRNPRKKAAKELRLQGAEVVQGDQDDQVIMELALNGAYATFIVTNYWESCSQEQEVKQGKLLADLARRLGLHYVVYSGLENIKKLTAGRLAAAHFDGKGEVEEYFRDIGVPMTSVRLPCYFENLLSHFLPQKAPDGKSYLLSLPTGDVPMDGMSVSDLGPVVLSLLKMPEKYVGQNIGLSTCRHTAEEYAALLTKHTRKVVHDAKMTPEDYEKLGFPGARDLANMFRFYALRPDRDIELTLRLNPKALTLDQWLEQHKGDFNLL