wanglab/gogpt-training-data huggingface dataset:
Protein: Mitochondrial ornithine carrier protein AmcA/Ort1, putative (Q4WBL9)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Subcellular location: Mitochondrion membrane {ECO:0000256|ARBA:ARBA00004225}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004225}.
Interaction partners:
- Ornithine carbamoyltransferase, mitochondrial
- Acetylglutamate kinase, putative
Sequence:
MAAAEHVLAIDNEKSMELPVLPPNQGFEAFKDIIFGSAAGMAGKVIEYPFDTVKVRLQSQPSHIPLRYQGPLDCFRQSIQADGLRGLYRGISAPLAGAAIENSCLFFSYRIIQDILRATCYPTADSMPFSALLFSGAASGSITSLALTPIELIKCKMQVPLEASSSKMPGPLTLIAAIFRQDGILGFWRGQMGTLIRETGGGAAWFGGYEGVSAFFRKYHSTVSPRDSESLPIYQQMIAGAAAGISYNFLFYPADTVKSRMQTEDINSPGNSGHRQTFWSVGRALWKQQGLRALYRGCGITCARSAPSSAFIFTIYEGLRNCFS
Protein: Discoidin-2 (Discoidin II) (P42530)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Galactose-binding lectin. May be necessary for the primary process of spore formation and may be involved in spore coat formation.
Interaction partners:
Sequence:
MSVPAGSVSCLANALLNLRSSTDYNADHGVKNSILNFSNSKDASRFDGSESWSSSVLDKNQFIVAGSDSVKHFVAISTQGRGDHDQWVTSYKLRYTLDNVNWVEYNNGEIINANKDRNSIVTINFNPPIKARSIAIHPQTYNNHISLRWELYALPVKSYSNPSVQVGEVSIGDRSLNSGTGSRTIVRHVKFPVEFLSVPIVSIGCKKVDAHTDNGQMRWEGKSENITTKGFDLTFITWGNNAVYDLTFDYVAVEFNN
Protein: Homeobox-leucine zipper protein ATHB-14 (HD-ZIP protein ATHB-14) (Homeodomain transcription factor ATHB-14) (Protein PHABULOSA) (O04291)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor involved in the determination of adaxial-abaxial polarity in ovule primordium. Specifies adaxial leaf fates.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Protein LITTLE ZIPPER 3
- Probable transcription factor KAN2
- Transcription repressor KAN1
- Prohibitin-6, mitochondrial
- Probable transcription factor KAN3
- Axial regulator YABBY 1
Sequence:
MMMVHSMSRDMMNRESPDKGLDSGKYVRYTPEQVEALERVYTECPKPSSLRRQQLIRECPILSNIEPKQIKVWFQNRRCREKQRKEAARLQTVNRKLNAMNKLLMEENDRLQKQVSNLVYENGHMKHQLHTASGTTTDNSCESVVVSGQQHQQQNPNPQHQQRDANNPAGLLSIAEEALAEFLSKATGTAVDWVQMIGMKPGPDSIGIVAISRNCSGIAARACGLVSLEPMKVAEILKDRPSWLRDCRSVDTLSVIPAGNGGTIELIYTQMYAPTTLAAARDFWTLRYSTCLEDGSYVVCERSLTSATGGPTGPPSSNFVRAEMKPSGFLIRPCDGGGSILHIVDHVDLDAWSVPEVMRPLYESSKILAQKMTVAALRHVRQIAQETSGEVQYGGGRQPAVLRTFSQRLCRGFNDAVNGFVDDGWSPMGSDGAEDVTVMINLSPGKFGGSQYGNSFLPSFGSGVLCAKASMLLQNVPPAVLVRFLREHRSEWADYGVDAYAAASLRASPFAVPCARAGGFPSNQVILPLAQTVEHEESLEVVRLEGHAYSPEDMGLARDMYLLQLCSGVDENVVGGCAQLVFAPIDESFADDAPLLPSGFRIIPLEQKSTPNGASANRTLDLASALEGSTRQAGEADPNGCNFRSVLTIAFQFTFDNHSRDSVASMARQYVRSIVGSIQRVALAIAPRPGSNISPISVPTSPEALTLVRWISRSYSLHTGADLFGSDSQTSGDTLLHQLWNHSDAILCCSLKTNASPVFTFANQTGLDMLETTLVALQDIMLDKTLDEPGRKALCSEFPKIMQQGYAHLPAGVCASSMGRMVSYEQATVWKVLEDDESNHCLAFMFVNWSFV
Protein: Activating signal cointegrator 1 complex subunit 1 (Zgc:112403) (Q566X5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MEVLRPPLININGRIYRKNPVQEETYEEEEEDCSYSEAAVDQCLDEPCDAHNIEQTDRGFRCALDVPSVLYKYIIGKKGETRRRLESETKTSINIPKQGVEGQIVVTGAHRPSVSSAVTRIEVLIDSFRRKQPFTHFLSFALNHAQVREGFLRFREEVLEHCSQDSGVDVSIFQNPDKLHLTIGTLVLLNQQEVTRANELLHQCQDTIREITGAEALPVEVRGVEYMNDDPSMVDVLYAKVSVQDGSDRLQQISDRLVECFVSAGLMERERDRVKIHATVMNTLFRRDPSAEDRGAPARANPRDREAFNGKNILQMFGDFYFGAFELNSVQISQRFSTDSSGYYSSAGHITFS
Protein: Sodium/hydrogen exchanger 5 (Na(+)/H(+) exchanger 5) (NHE-5) (Solute carrier family 9 member 5) (Q9Z0X2)
Organism: Rattus norvegicus (Rat)
Function: Plasma membrane Na(+)/H(+) antiporter. Mediates the electroneutral exchange of intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry. Responsible for regulating intracellular pH homeostasis, in particular in neural tissues. Acts as a negative regulator of dendritic spine growth. Plays a role in postsynaptic remodeling and signaling. Can also contribute to organellar pH regulation, with consequences for receptor tyrosine kinase trafficking (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q14940}; Multi-pass membrane protein {ECO:0000255}. Recycling endosome membrane {ECO:0000250|UniProtKB:Q14940}; Multi-pass membrane protein {ECO:0000255}. Cell projection, dendritic spine membrane {ECO:0000250|UniProtKB:Q14940}; Multi-pass membrane protein {ECO:0000255}. Synaptic cell membrane {ECO:0000250|UniProtKB:Q14940}; Multi-pass membrane protein. Cell junction, focal adhesion {ECO:0000250|UniProtKB:Q14940}. Note=Cycles between recycling endosome and plasma membrane in response to diverse stimuli. Its internalization is clathrin- and beta-arrestin dependent and its plasma membrane insertion from the recycling endosomes requires phosphoinositide 3-kinase (PIK3CA) and SCAMP2. {ECO:0000250|UniProtKB:Q14940}.
Interaction partners:
Sequence:
MLRVALLLLPGLPLAGVGATEEPTQEPGPLGEPPGLALFRWQWHEVEAPYLVALWILVASLAKIVFHLSRKVTSLVPESCLLILLGLALGGIVLAVAKKAEYQLEPGTFFLFLLPPIVLDSGYFMPSRLFFDNLGAILTYAVVGTLWNAFTTGVALWGLQQAGLVAPRVQAGLLDFLLFGSLISAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVLYKVCNSFVEMGSANVQATDYLKGVASLFVVSLGGAAVGLVFAFLLALTTRFTKRVRIIEPLLVFLLAYAAYLTAEMASLSAILAVTMCGLGCKKYVEANISHKSRTAVKYTMKTLASSAETVIFMLLGISAVDSSKWAWDSGLVLGTLFFILFFRALGVVLQTWVLNQFRLVPLDKIDQVVMSYGGLRGAVAFALVILLDRTKVPAKDYFVATTIVVVFFTVIVQGLTIKPLVKWLRVKRSDYHKPTLNQELHEHTFDHILAAVEDVVGHHGYHYWRDRWEQFDKKYLSQLLMRRSAYRIRDQIWDVYYRLNIRDAISFVDQGGHVLSSAGLTLPSMPSRNSVAETSVTNLLRESGSGACLDLQVIDTVRSGRDREDAVMHHLLCGGLYKPRRRYKASCSRHFISEDAQERQDKEVFQQNMKRRLESFKSTKHNICFTKSKPRPRKTGHKKKDGVANPEATNGKPPRDLGFQDTAAVILTVESEEEEESESSETEKEDDEGIIFVARATSEVLQEGKVSGSLEVCPSPRIIPPSPTCAEKELPWKSGQGDLAVYVSSETTKIVPVDMQTGWNQSISSLESLASPPCTQPPTLTRLPPHPLVPEEPQVPLDLSSDPRSSFAFPPSLAKAGRSRSESSADIPQQQELQPLMGHKDHTHLSPGPANSHWCIQFNRGGRL
Protein: HIVEP zinc finger 1 (F1M9H4)
Organism: Rattus norvegicus (Rat)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MTVEASESGDSVSPKKASSPHHRSELRRWRSEGSDPARLSGLDGQRDSSSSSSKTRTDNSECSSPCCSTTPPSYTSTAFDVLLKAMEPELSTLSQKGSSCAVKTEKPRPNRTVRSPSKLKNSSLDAPNPASPELVAESQCSPCTSYPVPVASTQKSEQVAAQRVSHLHSQYDHLVPKPGQQNPQLPGHLGLAGSLTNPHTHENTKLEPIYNIAMTSTVGLASPSSRTQVTPPHQQMDSVSPSSVSPATSTQSPPGPIYSSTHVASVVSQSVEQMCNLLLRDQKPKKQGKYICEYCNRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHTIKLGLVLQPEAGGLFLSQECPKALSVHSDIEDSGESDEEGPGDGRQNDPSVRDLQPVQIMKMPSDPEALPKSIASRADHVVSGFSSQDRPSESQALTELPKVVVHPVSMSPLKTDSVQVASPKPELPSTQSQKDLHAASRLSHSAGVSSLETDETCHQKGDVTLSEGKPEPHSGAAHAQLQRQQATDDPQEQQGKLLLSPRSLGSTDSGYFSRSESADQAMSPPTPFARTFPTTDPDPAKNSGPAGPRISAPAPAALAPGEKSSVVAGQMRPPLATKTLEERISKLISDNEALVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPMGRRTSSSSDIPKSPFTPTEKSKQVFLLSVPSLDCLPITRSNSMPTTGYSAVPANIIPPPPPLRGSQSFDDKIGTFYDDVFVSGPNPSMPPSGHHRPLVRQAAVEDSTASENHVLGSGQSVDESCQGCPASSEPGPVQSKAANTPHLEKKKSHQGRGTMFECETCRNRYRKLENFENHKKFYCSELHGPKTKVAAREPEHGLAPGGVQPQVLHYRVAAPTAVWEQTPQIRKRRKMKSVGDDEDLQPRESGRSPESAEALQLQPVPGSAPSPSKQAPATAGDQAHRGVQLQSSPVQLVARVPEQALPLKQCPVVEQQLNSATQDRIEVQRQAGGISVIQHTNSLSRPSSFDKLEPLEGGTAFSLQELGRAGMPGALKVIGMPPEEGHPPRDATHQIALSRESARKIPSERFVLGQPLRLVRQHNIQVPEILVTEEPDRDLEAQSHDEEKSEKFTWPQRSETLSKLPTEKLPPKKKRLRLAEIEHSSTESSFESTLSRSLSRESSLSHASSFSASLDVEDISKVELSPKTDFPSKAEFLFIPLGSNTLSVPGSHREMRRAASEQISCVPTLMEVSDFRSKSFDCGSIAPSHVVPALVEPQPSNSPSGVGGTGHVPLLERRRGPLTRQISLNIASDSPLSPGSVSALQTIVLPGVNAIPLQALRPPDVASADLPAHTVPSQALAKDLQAEMSSCSSTDTFPPQQLFGAHLLNKTNMPLSHQNTPLPLPVSVQGGKPGAPPPAGTSSTGDGSFAPKYQLQCQAFTSGRGCSSSPLHSLPNPVLPDQTAADPCTASVALSAKAVDPVSKSYPLPSLELGLPSDQVQKRLPSFVLPVLQPRDVPVYCLSTVTSLPQILVTHDLSNTPICQTNQSIVPVSEEQNPMPKSQNYLQNALPTPEKDLACKTVLSEMGQNAPVSESSATVQKVSAGRLSPQQESSASSKRMLSPANSLDIAMEKHQKRAKDENGAVCSTNIRPLELPSSRANEGHKQKKPVLVRQLCTVEPLEGTALEQDPGSASGKSSRNADSTQVLSTDSLSSRHSMFAVPDHVSEFQEFKNTKLSTSLTPTVGSSHIPLESACVLPLKSRDDNQEKGSSGVQNEENKVIQGQRQPPIPGLSVLSSSDTQQPSFPSLKTATSFTWCYLLRQKSLPLAQSDQKTSAYAGWTVSPSNPNPLGLPTKVALSLLNSKQKTGKSLYCQAITTHSKSDLVVYSSKWKNNLSKRALGNQKATIVEFSNKDDSEINSEQDKENSLIKSEPRRIKIFDGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYHCTYCNFSFKTKGNLTKHMKSKAHSKKCVDLGISVGLIDEQDTEESDEKQRFGCERSGFDLEESDGPDEDDNDNEEDDDDSQAESGLSAAPSVTASPQHLPSRSGLQDPGSVEEDLRVSSCFSGVHTDPMDILPRALLTKMTVLSTVQIDPNRTDLTAKARQNTGKDELELAPPVDTPISPEVTPRSPGHQMSVHYSESDALRSPAAGNTVASIQDSPSVGLPPATIAQLNPQPAARISSSVSPHPESQEPKQQITLQPSPGLPSPQTHLFSHLPLHSQQQSRTPYNMVPVGGIHVVPAGLTYSTFVPIQAGPMQLTIPAVSVIHRTVGTPVDTITEVSGATNRPTGVAELSSVVPCIPIGQIHVPGLQNLSPPALQSLSSLGMETVNIVGLANATVGPQVHPPGLALNAVGLQVLANAPAQSSPATQTHIPGLQILNIALPTLIPSVGPVAVGTAGTPETATSNSKTVEPQTPAGQGHSAEPPQRLPEGPQETPQTVPGPSVDHARPDGSSKMDTKKVASASHVLPGRSSAQAQPAPIPEALQKIVASGPTSLPTDRPAPRPPVPHRQPIVHFSDVSSDDDEDRLVIAT
Protein: At1g78070/F28K19_28 (Transducin/WD40 repeat-like superfamily protein) (Q94JT6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Mitotic checkpoint protein BUB3.3
- Transducin/WD40 repeat-like superfamily protein
- Protein ROOT INITIATION DEFECTIVE 3
- Guanine nucleotide-binding protein subunit beta
- Notchless protein homolog
- RNA binding
- Apoptosis inhibitory protein 5
- At2g43770
- RNA-binding
- DNA repair metallo-beta-lactamase family protein
Sequence:
MDIFDNSDLEYLVDEFHADFDDDEPFGEVDVTSESDSDFMDSDFDFELSESKTNNETSALEARNGKDIQGIPWESLNYTRDRYRENRLLHYKNFESLFRSREELDKECLQVEKGKNFYDFQFNTRLVKSTIAHFQLRNLVWATSKHDVYFMNNYSLMHWSSLLQRGKEVLNVAKPIVPSMKQHGSLSQSVSRVQISTMAVKDDLIVAGGFQGELICKKINEPEVAFCTKLTSADNDITNSVDIYNAPSGSLRVMTANNDCTVRLFDATNFALLNRFAFHWSVNNISTSPDGKLVAVLGDSPECLLADTGSGKVIHGLEGHLDYSFSSAWHPNGQILATGNQDTTCRLWDVRNLSQSLKVLKGNMGAIRALRFTSDGRFLAMAEPADFVHLFDTEAGYSQCQEIDLFGEIAGISFSPDTEALFVGVADRTYGSLLEFNRKRNHSYVDSIF
Protein: Peptidyl-prolyl cis-trans isomerase FPR2 (PPIase FPR2) (EC 5.2.1.8) (13-kDa membrane-associated FK506-binding protein) (FKBP-13) (FK506-binding protein 2) (FKBP proline rotamase 2) (FKBP-15) (P32472)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. FKBP-13 may play a role in protein trafficking in the ER.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Note=Is not secreted and probably localized in the endoplasmic reticulum. {ECO:0000305|PubMed:1380159}.
Interaction partners:
- Peptidyl-prolyl cis-trans isomerase D
- Peptidyl-prolyl cis-trans isomerase B
- Peptidyl-prolyl cis-trans isomerase CPR6
- Peptidyl-prolyl cis-trans isomerase
- Peptidyl-prolyl cis-trans isomerase C, mitochondrial
- Vacuolar membrane protein YPL162C
- Protein disulfide-isomerase EUG1
- Heat shock protein 70 homolog LHS1
- Endoplasmic reticulum chaperone BiP
- Protein disulfide-isomerase
Sequence:
MMFNIYLFVTFFSTILAGSLSDLEIGIIKRIPVEDCLIKAMPGDKVKVHYTGSLLESGTVFDSSYSRGSPIAFELGVGRVIKGWDQGVAGMCVGEKRKLQIPSSLAYGERGVPGVIPPSADLVFDVELVDVKSAA
Protein: Serine/threonine-protein kinase meng-po (meng-po) (EC 2.7.11.1) (SH3-binding kinase homolog) (Q9VM90)
Organism: Drosophila melanogaster (Fruit fly)
Function: Serine/threonine-protein kinase involved in memory formation. Together with the cAMP-dependent protein kinase A Pka-C1, promotes long-term memory (LTM) by regulating CrebB stability and activity. Involved in the maintenance of anesthesia-sensitive memory (ASM) which includes short-term memory (STM) and middle-term memory (MTM).
Interaction partners:
Sequence:
MGTIEKRSFSFRLRRSFGDGGSTNSRNSNNNSSTCTNHNNQKRCSTPLTPTSTSTGRLEVPGAASVSRRSSIYKKPDKNDGGQIHLIPDVELPLMTFADQYNIEKTLAEGCFAKILLCRHRPTNTLVVLKAVHAELTTIKEFQKEFHYNYELSHHHHILSAYAVAFQTMDYYVFAMEHAPYGDLASNIGPNGLHENACKLISEQLSSALGFMHSKNLVHRDLKIENILVFTPDFTRVKLCDFGATTKKGLLVHKVKHTWTSCVPPEQLELIKNERFQCLPVSDSWQFGILLYNILTGNPPWQSADWVKDQSYANFMKYEQRKTTKVPDNFRRFSPRLMRCFRKYLSHDPEDRCKITEVAKYMKDRWVECRISTSKSATLISPTNHDQDSCIYLNQREGRLSGDENKLRFKRMMSTYGLDIPIDQAMVRRRVWDWLSTCDANFDPDVESLHALDLLQ
Protein: Enoyl-CoA hydratase (Eurofung) (C8V3K8)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- 3-hydroxybutyryl-CoA dehydrogenase, putative
- Acyl-coenzyme A oxidase
- Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
- Acyl-CoA dehydrogenase family protein
- acetyl-CoA C-acetyltransferase
- 3-ketoacyl-CoA ketothiolase
- acetyl-CoA C-acyltransferase
- acetyl-CoA C-acyltransferase
- Uncharacterized protein
- Probable electron transfer flavoprotein subunit alpha
Sequence:
MFARQSTRFLFPRTTTVITRVRLYSSAAPSYEHILTSTPKPGVGLITLNRPKALNALSSPLFKEVNDALSKYDESKDIGAIIITGSEKAFAAGADIKEMAPLTFASAYSNNFIAPWSHLANSIRKPVIAAVSGFALGGGCELALMCDIIYCTASATFGQPEIKLGVIPGAGGSQRLTAAVGKSKAMELILTGKNFSGKEAGEWGVAAKVVDGGKEELLEEAVKTAETIAGYSRVATVAAKEVVNKSQDLGVREGVEYERRLFHGLFGSQDQKIGMTAFAEKKKPQWSHE
Protein: Rv3651-like N-terminal domain-containing protein (O06357)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MTHDWLLVETLGDEPAVVARGRELKKLVPITTFLRRSPYLAAVRTAIAETLQTGQSLTSITPKHDRVIRTEPVIMTDGRMHGVQVWSGPTDAEPPDRPIPGPLKWDLTRGVATDTPESLTNSGKNPEVEITYGRAFAEDLPARELNPNETQVLAMAVKAKPGKTLCSIWDLTDWQGTPIRIGFVARSALEPGPNGRDHLVARAMNWRAETKAPAVPVDDLAQRILIGLAQAGVHRALVDLKTWTLLKWLDQPCSFYDWRRSAADGPRLHPDDQHVIDAMTRDLANGSASHVLRLPGHDVDWVPVHVTVNRIELEPDTFAGLVALRLPTDEELADAGLPKATDVTT
Protein: Adenine nucleotide alpha hydrolases-like superfamily protein (Q93W91)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Transducin/WD40 repeat-like superfamily protein
- Adenine nucleotide alpha hydrolases-like superfamily protein
- WD repeat-containing protein 76
- At1g01170)
- Tetratricopeptide repeat protein SKI3
- UDP-sugar pyrophosphorylase
- Probable peroxygenase 4
Sequence:
MEETKERKIVVAVDESEESMEALSWSLDNLFPYGSNNTLILLYVKPPLPVYSSLDAAGFIVTGDPVAALKKYEYELVESVMARSRTVYQDYESDINIERRVGRGDAKEVICNAVQKLRVDMLVMGTHDYGFFKRALLGSVSEYCAKRVKCPVVIVKKQAQDN
Protein: Cysteine-rich protein 1 (CRP-1) (Cysteine-rich intestinal protein) (CRIP) (P63255)
Organism: Rattus norvegicus (Rat)
Function: Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein.
Interaction partners:
Sequence:
MPKCPKCDKEVYFAERVTSLGKDWHRPCLKCEKCGKTLTSGGHAEHEGKPYCNHPCYSAMFGPKGFGRGGAESHTFK
Protein: Pumillo RNA binding protein PUF1 (Q4FKQ5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSSDEETITTLYLRRQNILKQLSEVNNEIRTAEQQINEKSNNNETRRVEELVVKFGGDDDRESYLLDFCMRDANGLREAIRYVDALKALKECTSDDEVNRKKHLSRNTFVHAMIARSGELMVDANGSELIQHALGMLKSGGKVAPVLYSTDYIAASESDLSEFLLLLEVLKDKIPQICCDTNGSRAMQKVFDSLKSLEEVEFSAQCFSECIIELCKDIDGNHAVSRLLAAARGTPLWESGAAGDDSSSKLAHIHQLLYGKFPESCVDVCGNRHGCCVIQKCLQWAPEPYFSTLMDTIVHDTIKLVHDPFGNYVIQFILDHEQELSQRSSTGSEGADYTNRIIRQMLHNVAALSCNKFCSNVIEKCLKSATPDVRQLLVDELTDPQILPKLLTDSFANYVIQTAIVTSTEEKQFTQLRDSIMPLQRMLKNSPHGVKVESKLVRQQRELARKNGNQKNKKRWAQPAPQVMEKGMHEGFIGTHILPGMAGIPTIVGTDEFGGPALSLPGVAKEAVPIMTPTQYMPLMLPGQQTLIGLPQGYPQQQFPMDIMKGGNIWDPQQGFTLLHHPESKKGT
Protein: Protein dimmed (B6VQA1)
Organism: Drosophila melanogaster (Fruit fly)
Function: Transcription factor that regulates neurosecretory (NS) cell function and neuroendocrine cell fate. Acts as a master regulator of common NS functions such as Phm expression and neuropeptide production. Plays a role as a regulator of peptide-containing large dense-core vesicle (LDCV) production and peptidergic cell differentiation. Controls transcription of FMRFamide in Tv neuronal cells and Fur1 in Ap-let cells (Tvb and dorsal apterous cells). Also required for up-regulation of Phm in Tv and Ap-let cells, and expression of three neuropeptide genes, Ms, FMRFamide and Lk. Influences both regulated and constitutive secretory activity in neuroendocrine cells at embryonic and postembryonic level. Loss of function studies show reduced cellular levels of various neuropeptides and neuropeptide biosynthetic enzymes.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16870731}.
Interaction partners:
- Zinc finger protein squeeze
- Neuropeptide-like 1
- Peptidylglycine alpha-hydroxylating monooxygenase
- FMRFamide-related peptides
- FI04531p
Sequence:
MDATQLTELMGSHDFMQLQHQLHHNNNNYNTDGHNGLSSESAEGSSRPVRRATRRTSQLSNNTYDLEMTDSSSQSDDTSGGGGSSNGGGSTTNTGHPSGCSLGGQGPSGRGRVQQASSGACPSTIAPNSTSSNSSNANGNASRRRKGALNAKERNMRRLESNERERMRMHSLNDAFQSLREVIPHVEMERRLSKIETLTLAKNYIINLTHIILSKRNEEAAALELNSGAVGGVLLSNLSSESGGPVASGIPANSNAATICFEDTLASGGAFDCAILAATDGSLLNAATVTTSPAMQSIQSQAIHLQTPMEQQQQQASHLPHHQQAMHGHGHLGASIQSQQQPSLVLNGTTSVGLGIGIGVGVGVGVGVCNNAPSFADINDNFDEPFREFL
Protein: N-acetyltransferase 8F1 (EC 2.3.1.-) (Camello-like protein 1) (GCN5-related N-acetyltransferase 8, family member 1) (Q9JIZ0)
Organism: Mus musculus (Mouse)
Function: May play a role in regulation of gastrulation.
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Aminopeptidase N
- Cytosol aminopeptidase
Sequence:
MVPYHIRQYQDSDHKRVVDVFTKGMEEYIPSTFRHMLMLPRTLLLLLGVPLALVLVSGSWILAVICIFFLLLLLRLLARQPWKEYVAKCLQTDMVDITKSYLNVHGACFWVAESGGQVVGIVAAQPVKDPPLGRKQLQLFRLSVSSQHRGQGIAKALTRTVLQFARDQSYSDVVLETSALQQGAVTLYLGMGFKKAGQYFMSIFWRLAGICTIQLKYSFPSA
Protein: AT4g00300 protein (A_IG005I10.16 protein) (F5I10.16 protein) (O23072)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MGDQKTLSYDKSNKPFYSSSSSPCSFTAIVVFLIFVSYLLYSFSFISFLNPYSPSKSPNSLLVPVIRLGSGQTPEEQTELKHIVFGIAASSDLWKHRREYVKTWWKPNGVMNGAVWLDKPINDTVSSSSALPQIRISSDTSSFKYRYRNGHRSAIRITRIVSETVRMLNGTEAERNVRWVVMGDDDTVFFTENLVRVLRKYDHKQFYYIGAPSESHLQNLHQFSYGMAYGGGGFAISYPLAKVLEKMQDRCIERYSDLYGSDDRIHACMAELGVPLTKEVGFHQFDVYGNLLGLLSVHPQAPIVSIHHLDVVDPIFPKTNRVNALKKLMIPAKLDSASLVQQSVCYDKSHQWTMSISWGYTVQITRTYMPARMMEVPTRTFNDWHLRSDFTNLAFNTRPVTWTDCQRPRVFYFSHAFSNSSSSDTTTISQYLRHDEWYPKCEWGIADPSEINQIFVYKKPTPDRWSKVVIRFVPSKDSNFAFVNAIEVISAPKDLIGDVATSVSHDGTEKFNGLAKQAMEVVYRVNVGGRKVTPFNDTLWRTWVTDEGFLKTGDGSSEKSYFTGRIKYRRGGASREVGPDNVYNTARVGKRSNGLVDMSWGFKVNVGYKYLIRMHFCDIASKSLGRLYFNVYINGNLAYEDFDISYAADNVLASPYYIDFVVDATADDNNPSGSSITVSVGPSNKTSVDGNGVDAILNGVEIMKMNNSMGSLDGYVSTEMILSTCPNRRNLSIFIAMLAFMCIFMSFYIVTQRKRVKDQYGWTKLSMDVLEDNSKSGNQFTARKA
Protein: Uncharacterized protein LRP2 (Q53TL0)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
MDRGPAAVACTLLLALVACLAPASGQECDSAHFRCGSGHCIPADWRCDGTKDCSDDADEIGCAVVTCQQGYFKCQSEGQCIPNSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSNGQCIPSEYRCDHVRDCPDGADENDCQYPTCEQLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEICLHNEFSCGNGECIPRAYVCDHDNDCQDGSDEHACNYPTCGGYQFTCPSGRCIYQNWVCDGEDDCKDNGDEDGCESGPHDVHKCSPREWSCPESGRCISIYKVCDGILDCPGREDENNTSTGKYCSMTLCSALNCQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDDCQIWGICDQKCESRPGRHLCHCEEGYILERGQYCKANDSFGEASIIFSNGRDLLIGDIHGRSFRILVESQNRGVAVGVAFHYHLQRVFWTDTVQNKVFSVDINGLNIQEVLNVSVETPENLAVDWVNNKIYLVETKVNRIDMVNLDGSYRVTLITENLGHPRGIAVDPTVGYLFFSDWESLSGEPKLERAFMDGSNRKDLVKTKLGWPAGVTLDMISKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKANKFTETNPQVYYQASLRPYGVTVYHSLRQPYATNPCKDNNGGCEQVCVLSHRTDNDGLGFRCKCTFGFQLDTDERHCIAVQNFLIFSSQVAIRGIPFTLSTQEDVMVPVSGNPSFFVGIDFDAQDSTIFFSDMSKHMIFKQKIDGT
Protein: Small protein MntS (P0DKB3)
Organism: Escherichia coli (strain K12)
Function: Required for repression of mntH by MntR. May function as a chaperone that makes manganese more available by delivering it to the necessary cellular locations when manganese is limiting.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21778229}. Note=May be loosely associated with the inner membrane.
Interaction partners:
- Transcriptional regulator MntR
- Probable manganese efflux pump MntP
- Cytochrome bd-I ubiquinol oxidase subunit X
- Multidrug efflux pump accessory protein AcrZ
Sequence:
MNEFKRCMRVFSHSPFKVRLMLLSMLCDMVNNKPQQDKPSDK
Protein: Putative calcium-dependent cell adhesion molecule 2 (CAD-2) (DdCAD-2) (O97113)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Mediates calcium-dependent cell-cell adhesion during the early stage of development.
Subcellular location: Cell membrane {ECO:0000250}.
Interaction partners:
Sequence:
MSTLGDKESIIFKEKSFGGEKWSLQNGSRYGNQAGALRSLKVGKFCKVNIWDKNGTMQTFLGGEYPDITDKLPNVDIVQAIDVQFKYSVDIRFKHNVQGRDPNDFKLTVIPYQLNGVEIVSGGDYSGVQIPELNPPDSEIVCQISIREIKWPGQVFANGSIYFKYTPSNNTVSYRKTEGWPTNCEIVQDDVSGFTITLKSI
Protein: Myosin regulatory light chain 12B (Myosin regulatory light chain 2-B, smooth muscle isoform) (Myosin regulatory light chain 20 kDa) (MLC20) (Myosin regulatory light chain MRLC2) (Q3THE2)
Organism: Mus musculus (Mouse)
Function: Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion.
Interaction partners:
- Myosin light polypeptide 6
- Myosin-9
- Myosin-10
- Protein phosphatase 1 regulatory subunit 12A
- Rho-associated protein kinase 2
- Myosin light chain 6B
- Myosin-11
- Rho-associated protein kinase 1
- Actin, cytoplasmic 2
- Actin, cytoplasmic 1
Sequence:
MSSKKAKTKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD
Protein: P2Y purinoceptor 1 (P2Y1) (ADP receptor) (Purinergic receptor) (P47900)
Organism: Homo sapiens (Human)
Function: Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation.
Subcellular location: Cell membrane {ECO:0000269|PubMed:25822790}; Multi-pass membrane protein {ECO:0000269|PubMed:25822790}.
Interaction partners:
- P2Y purinoceptor 12
- Guanine nucleotide-binding protein G
- P2X purinoceptor 1
- Guanine nucleotide-binding protein G
- Ectonucleoside triphosphate diphosphohydrolase 2
- RRP15-like protein
- Ribosome biogenesis protein BOP1
- Ribosomal L1 domain-containing protein 1
- Surfeit locus protein 6
- Ribosome production factor 1
Sequence:
MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLNILPEFKQNGDTSL