wanglab/gogpt-training-data huggingface dataset:
Protein: Carbohydrate sulfotransferase 2 (EC 2.8.2.-) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 2) (GST-2) (N-acetylglucosamine 6-O-sulfotransferase 1) (GlcNAc6ST-1) (Gn6ST-1) (Q9Y4C5)
Organism: Homo sapiens (Human)
Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues within keratan-like structures on N-linked glycans and within mucin-associated glycans that can ultimately serve as SELL ligands. SELL ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Participates in biosynthesis of the SELL ligand sialyl 6-sulfo Lewis X and in lymphocyte homing to Peyer patches. Has no activity toward O-linked sugars. Its substrate specificity may be influenced by its subcellular location. Sulfates GlcNAc residues at terminal, non-reducing ends of oligosaccharide chains.
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:12855678, ECO:0000269|PubMed:22260995}; Single-pass type II membrane protein {ECO:0000269|PubMed:12855678, ECO:0000269|PubMed:22260995}.
Interaction partners:
- Carbohydrate sulfotransferase 4
- Protein N-terminal asparagine amidohydrolase
Sequence:
MSRSPQRALPPGALPRLLQAAPAAAPRALLPQWPRRPGRRWPASPLGMKVFRRKALVLCAGYALLLVLTMLNLLDYKWHKEPLQQCNPDGPLGAAAGAAGGSWGRPGPPPAGPPRAHARLDLRTPYRPPAAAVGAAPAAAAGMAGVAAPPGNGTRGTGGVGDKRQLVYVFTTWRSGSSFFGELFNQNPEVFFLYEPVWHVWQKLYPGDAVSLQGAARDMLSALYRCDLSVFQLYSPAGSGGRNLTTLGIFGAATNKVVCSSPLCPAYRKEVVGLVDDRVCKKCPPQRLARFEEECRKYRTLVIKGVRVFDVAVLAPLLRDPALDLKVIHLVRDPRAVASSRIRSRHGLIRESLQVVRSRDPRAHRMPFLEAAGHKLGAKKEGVGGPADYHALGAMEVICNSMAKTLQTALQPPDWLQGHYLVVRYEDLVGDPVKTLRRVYDFVGLLVSPEMEQFALNMTSGSGSSSKPFVVSARNATQAANAWRTALTFQQIKQVEEFCYQPMAVLGYERVNSPEEVKDLSKTLLRKPRL
Protein: Aquaporin NIP6-1 (NOD26-like intrinsic protein 6-1) (AtNIP6;1) (Q9SAI4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transports glycerol, urea and formamide, in Xenopus laevis oocytes. Very low water transport activity.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Boron transporter 4
- Probable aquaporin SIP2-1
- Probable aquaporin SIP1-2
- Probable boron transporter 7
- ACT domain-containing protein ACR3
- NEP1-interacting protein 2
- Probable boron transporter 3
- Urea-proton symporter DUR3
- Aquaporin SIP1-1
- Boron transporter 1
Sequence:
MDHEEIPSTPSTPATTPGTPGAPLFGGFEGKRNGHNGRYTPKSLLKSCKCFSVDNEWALEDGRLPPVTCSLPPPNVSLYRKLGAEFVGTLILIFAGTATAIVNQKTDGAETLIGCAASAGLAVMIVILSTGHISGAHLNPAVTIAFAALKHFPWKHVPVYIGAQVMASVSAAFALKAVFEPTMSGGVTVPTVGLSQAFALEFIISFNLMFVVTAVATDTRAVGELAGIAVGATVMLNILIAGPATSASMNPVRTLGPAIAANNYRAIWVYLTAPILGALIGAGTYTIVKLPEEDEAPKERRSFRR
Protein: Paired-type homeobox protein (O96616)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Interaction partners:
Sequence:
MQVSGWSSVLNLSMDAPNPEISPNSVTNSSSVYMIRQMALIQQARVAAAAVAMQQQQQQQQQQQRDLNRELGMDPHSEQRIKLDSVSPTHNIHAGSSRGIKQDPLSDEGADSNLGQNDCTESSKKRRGRTNFNSWQLRELERVFQGSHYPDIFMREALATKLDLMEGRIAVWFQNRRAKWRKQEHTKKGPGRPAHNAHPQSCSGDPIPLSELRARELAQRSKRMKKAIDRQAKKLQDKGLEVDYARLEAEYLAVHQENGVDENNWLDDDGYDDLHIDVVGVEPEYVTGDSLDHSFCSSRTYQTKSTSSELDSNDMGLQGRVETPPPPQPPMQNKTLYNSPFSIESLLGS
Protein: Uncharacterized protein (Q38BI3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MNSSSALTAESPYASYPEVDWSFILSLPIDEWEKVVNPRDLRQFAEGVSKVYWNKDDKHFADRQCAVAIMRLLRIMAKVYLDNEDRFQQENGFLQHVVQTVCDTDEACRNRVTQLFKENEYFKVAFRHEENQAGVCGMRSPRGVELSGGHGVRHITEKYDKHARELDRLKHENEQLRRTAQFCEGEKASVVQENAKLQLEYKHLVAKHKRVIEKHNSVKEMLRETRRSEVDRLQDDESELKRLRQKVRELQLENHNLIQLRNRAEELCEQREMEALKDMTELQKLHHEVVDEERNRVQILTDELSRKQRDIDRRATQVVVERQRCPSHLREDDDKRHDMGKNLPMSNSSLGFGAMQSGGTAKRSSPSARNSSNLAETGPFRLKANIEERDTQILVADIQRLQQENDRLSVELQQMELRAEAREEEIVRINRLIKNYERGDEGLRRLRCELETSTRTLELLREENSQLRERLNAMTDSLTFSSALQELCIRVGVTQEEIERLRPRSTLYCSEVEMLKAEVITLKEEVDWLERERRHWMDRVRLQPLLDTKLRLELGLNPEQLKQLDKIVGQMKVGRVIVEEAGEENYKEKYFQELRLRRKEMEHFNDFVKQRMEEVLRELSGKTDFSSSVEAASALQRLRDRVDIIAASRVADENGEGAADTLRLREQLQSALQLLEQSELTIKDNAATQTTLREQLAATTAERDMLLDERDKYRSAFFEGLVFDDTVEDSPQILETKEGAVDNLGPSRIPSSAEGAFSPPSFPEGCNCGTPVRSSSLNYLKRTFENQLRKKDELITSLKSTVDVMKDQLSQQHAVHEEMKRKCTEASSQQEDVRNQVAALQEMNRELTEKLNERTNILKDVEGTIQRMESVNTRELLQKIVLLRQRETKLLQRLRRVMEMHGEASKSERSMREYVNTVFKSLKEALENTSTGFVLPRSSSSVCIENDVIDEMQQRLGGILRGRLFREDSTYLLHLQRVYRNMEHIEELKVLRLEVQNQRAHRIVIEEKLEEQRVELECLRRLRDTVSEANEVKDGPVVGGGVISSVTRWESEVTTWQQKCNLYMKRCEDKEREVSTIEAQLGDARRELALLHEHIDNSIGSGTGTSGSGVPAVCSTPQDQQNGVAKEQRQQQEGAAIGHNRELGGIMSEGSKIYQLEREVARLKSINLGVLHYSLDLQGECKRLEIELEATKQELSLVRDAGNSQRLSDFVSAAIRQHSALRCQSELAVLQLKQARMQLHAMEANLRVAVNEATTYKLNAFRLYRKYVEQTVAVVDYVRSEQRCFAGALSPHRTEILHKRLMDAITDNERSQAIRSELAAQLAEARGNAALLQQQLELLKVKDGEGRVDALHAKLLASLSAVRDKDVKIVELREDCSFLQQKLKRAETHVQQLTEEISRLELNGTTLTAADGEAFRNLLQLKESVFSKSESPAVVIQQGDFGQRHQHEAVDMAAREYNQVMEKQGVLVHECDLLKKQLKEEGIAARKVTAENDALKGEVGRLRERLQNVQQQLHDERQRAEERERRVIRSHEAQAEVSHRAAEHHSRCLQDMLKSKDMCIEQLQGQLQAERRKYLECQVEESTRMERLHERLFKENSAMVERFREAINGAAEQYEYGAQLPDAGEPASGVSEHVAVLTKEVLRLRAELRNARTANIMLESRLSDQVADARRQQQHFPSVSGCPTEVERQHSHRTPQVPPSGATPAVDIIDDQSVVIANLRQRELALTDELQRAHTERDLLAQQLYEARNLTVEQGGVLKSVVAAKAAKPGVVETELRAQLSFLETQLAEAREKLDEERREARRLQTDTDKWREQLDSLREEIIKQQNDVERARRLVAMNERLNADIHHMEEQNEKLIIATNLLKQRLVDEAQERDSISRKHQHEMALAQRMGNIQQESSEHLKSVNLRLQSIQKELEEKVRREEETLRKHEEVQQLAYELHLQLQEKEHEILRLKRELAAQPSKVSLQGRRSPKRMQASHERGTQVLQTVQENGEGEVLAEVPWKVQQQRREGQELCQRGYLEGRPLEVMKSPREPLLHPALADCTNCSATPVVGSHVIDQSQVAAVARSEVEGAQRDNLNEISSLRALVSRQARDLKDVSEQLRGERDINNTLRSQLLSTRKELETRELGAVRETAILHQSLDERGKRHHRPSGVEKGHFSNPSALVSPLLQAAAGSNTQLIQQMEAKIKENEELQRQVEMLKSRLDSLDDAAQQIDFYKKELEELRRRQVNTPDCIQPTSPAGVRASKRAVLKLEAVIESLQRELRVENEVRFRSLEQRVAELIAENQRLTVELNRYQVIPTTAVTAPALNVLTSMKPSDQNSLERELLEKNGIILDLRFEREALQLKVSRLERHLDDVLKADSINMRVGGAHKERGRVEALETLVENMKVVVERLQQENSVLKSKTVSVAKHMDLVRELRELRSREKQLLEQSEKLSRRLLDSSMGGSAMSEQQARLQKRLQAAELTAERYRTEVQELRQRFKDVSSVQEGDTWPYSESQQKDSGDVHGTEDRRCVQPLPSLDSDLPPPLPRAPSF
Protein: Alpha-S1-casein (Alpha-casein) (P19228)
Organism: Mus musculus (Mouse)
Function: Important role in the capacity of milk to transport calcium phosphate.
Subcellular location: Secreted.
Interaction partners:
- Beta-casein
- Alpha-S2-casein-like B
- Kappa-casein
- Alpha-lactalbumin
- Alpha-S2-casein-like A
- Whey acidic protein
- Glycosylation-dependent cell adhesion molecule 1
Sequence:
MKLLILTCLVAAAFAMPRLHSRNAVSSQTQQQHSSSEEIFKQPKYLNLNQEFVNNMNRQRALLTEQNDEIKVTMDAASEEQAMASAQEDSSISSSSEESEEAIPNITEQKNIANEDMLNQCTLEQLQRQFKYNQLLQKASLAKQASLFQQPSLVQQASLFQQPSLLQQASLFQQPSMAQQASLLQQLLLAQQPSLALQVSPAQQSSLVQQAFLAQQASLAQKHHPRLSQSYYPHMEQPYRMNAYSQVQMRHPMSVVDQALAQFSVQPFPQIFQYDAFPLWAYFPQDMQYLTPKAVLNTFKPIVSKDTEKTNVW
Protein: At2g41380 (Putative embryo-abundant protein) (S-adenosyl-L-methionine-dependent methyltransferases superfamily protein) (Q9ZVC3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Plant intracellular Ras-group-related LRR protein 8
- At5g54100
- AAA-ATPase At2g18193
- Protein SENSITIVE TO PROTON RHIZOTOXICITY 2
- At5g09570
- Pectin lyase-like superfamily protein
- Zinc finger AN1 domain-containing stress-associated protein 12
- Pectinesterase inhibitor 11
- Protein PIN-LIKES 3
Sequence:
MAKLFIKQAEQYAAARPSYPTKLFEYIASKTPCHDLAWDVGAGSGQASRSLAGIYKNVIATDTSSKQLEFAAKLPNVRYEITPPTMSSSEIEKLVAPESSVDLVTVAQALHWFDLTNFYSNVKHVLKKPNGVIAAWCYTNPEVNDAVDKVFQRFYDEKLGPHWDLARRLVEDGYRGIEFPFEKVDNDESTESQSFPVRFVTEKEMVFEEYMTYLRSSSAYQTAKEKGLELLTAEMEGEFAGSWKEDGKEKKVVRYPIYLLIGRVAEERV
Protein: Sporulation-specific protein 1 (P38871)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation. May be required for the formation of ADY3 and DON1-containing protein coats at the leading edge of the PSMs during meiosis II.
Subcellular location: Prospore membrane {ECO:0000269|PubMed:11742972}. Note=Localizes to precursors of the PSM and to the leading edge, which cover the ring-shape opening of the PSMs during meiosis II. Some fraction colocalizes with DON1.
Interaction partners:
- Meiosis-specific APC/C activator protein AMA1
- Accumulates dyads protein 3
- Anaphase-promoting complex subunit CDC27
- Anaphase-promoting complex subunit 4
- Anaphase-promoting complex subunit 5
- Anaphase-promoting complex subunit CDC26
- Anaphase-promoting complex subunit SWM1
- Anaphase-promoting complex subunit 2
- Anaphase-promoting complex subunit 11
- Anaphase-promoting complex subunit CDC16
Sequence:
MRSSGTYENDPSGEITSTSPKQSKQKKPTKFRERMRRWLQNGKNNNHQGEEDVPEIFNKNFYPQTGMTAFNNNDNGEVQDVTNNFFLPSEDESGPVQSSVKTFLTGNNDEDSNFQQNQNPKQKSELPKSPYRQKPTQEIALLKDLFVTNKYDDPYLNSSTRFGNITSTFPSSLSLRTVTLQTIKKRIDCISAKKKEVWKTEEKFLKDILMWLQSSNFEDPDTISLIHEIEKIFEEDIHFEQNVSDCLKEISNNFEYICMRETQLINEGNILKNDLKKYAKAREHKGEKHEDTEVLREKVISSQKSFDVTKRHYKHAISITTRQLFMNLAFEYYENCSDMKDISRKYLQESLSTLQTIDTLSFSEELEKIRKRRFDKFWAKTNPDPTNNIQKFVNMRTGVAGFNDSLMNHLYGKLSFGVAPVEEELQNSQPEHTDVPENVWNEVLSDYNSMDGNPITSNKFLSAKELEPDQLVELLAQEKEEKEAKNISSSTAEVPSISQPEIKKENLESNDSLILRSTKRNVNVNAASLRNLSIKKTQVKPESASEESKVLAAALNDAKQNLDENVWRTPI
Protein: TWiK family of potassium channels protein 18 (Q18120)
Organism: Caenorhabditis elegans
Function: Outwardly rectifying potassium channel protein; activity is sharply augmented by increase in temperature.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MAIVAQGVSTILTTFQKTFKGLLPLIILVAYTLLGAWIFWMIEGENEREMLIEQQKERDELIRRTVYKINQLQIKRQRRLMTAEEEYNRTAKVLTTFQETLGIVPADMDKDIHWTFLGSIFYCMTVYTTIGYGNIVPGTGWGRFATILYAFIGIPLTVLSLYCLGSLFAKGCKMLWRFFLKSTRVVSKDLSNKISEAADNIEEGTTAITPSAEKTENNDDDLLSFPISGLLLITVIWVIFCAVLFTFLEEWDFGTSLYFTLISFTTIGFGDILPSDYDFMPIVGVLLLIGLSLVSTVMTLIQQQIEALASGMKDNIDQEYARALNEAREDGEVDEHVDPEEDPENNKKSFDAVISRMNWSKRGLYYLLPDSQKKELAKQSEKKMGRKSIKIQTDNDLLETLIREEILKAELNNEMHKYTAPRSSHQPKLVYSDVREKEVPIEVVRVEHFNHGNEDYLEHDI
Protein: Proline-rich protein 32 (B1ATL7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MACIENVLGGHAPSPLVVSVDKNGNQELHHDMPLQCLSSKPEDDAEPWGQPQVPLRPSVNVLTDLDSKQLEWPSERTGSCIPLHSLRAHRHPYGPPPAVAEESLATAEVNSSDALAGWRQEGQDAINVSWEVSGGPPALIVGGTKVNNGGTERGSNNARLHVALPQGKGFFPPRGPQVRGPSHIPTLRSGIVMEVPPGNTRIACRGKLAHVSFPLRGPCHPMHNWPRPIPLSSSTPGLPSCSTVHCFIPPRPPIFNPFLTMPLPFAPPPIFGPPLPSYFAHFHSGGMPAPASPNREHS
Protein: Synaptotagmin 7, isoform I (H9XVN2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MASIVLIACLAILGLIITIALFLAGGYLWWRHKRSQLQFIEPNEDEESSSYSLRAAQDIVDSGNPPTKPQVPVAHAITTPLQNNINRKLNGFLSLRTPLIGGSGASQTKPQIISSVGNPGDGTTKDSANKSISMTDMYLDSTDPSENVGQIHFSLEYDFQNTTLILKVLQGKELPAKDLSGTSDPYVRVTLLPDKKHRLETKIKRRTLNPRWNETFYFEGFPIQKLQSRVLHLHVFDYDRFSRDDSIGEVFLPLCQVDFAGKQSFWKALKPPAKDKCGELLSSLCYHPSNSILTLTLIKARNLKAKDINGKSGKNGSGASETKHWQDMISKPRQTVVQWHRLKPE
Protein: NAD(+) hydrolase TcpA (EC 3.2.2.6) (TIR domain-containing protein in T.archaeon) (tcpA) (A0A151EH88)
Organism: Theionarchaea archaeon (strain DG-70-1)
Function: NAD(+) hydrolase (NADase) that catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide.
Interaction partners:
- Proteasome-activating nucleotidase
- Translation initiation factor 2 subunit alpha
- protein-synthesizing GTPase
- Protein translation factor SUI1 homolog
- Glycerol kinase 5
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein eS4
- Large ribosomal subunit protein uL13
- Large ribosomal subunit protein eL40
- Small ribosomal subunit protein eS1
Sequence:
MAKSVSISYLALEQIFNDTIGAGEIKVAGLLVGHPVNGGVHIARTIPTSRGTVTYVRISAEEISRAVEELNPGEKIVGWYHSRPGQGVFFSQDDIETHEKCLDFNPYFQALVIDPHQAKYGTPMADCVRFYTVRNHKEVPIHGYKLTGSSMQSYYDPKEFVFDKYGFPHHYTLTHAGKTKISHRKSNMDASFEYDVFICHAHEDKEFFVRELAEKLHSKGLRVWYDEFTLSLGDNLRRSIENGLAKSRYGIVVLSKRFFEKEWPQKELDGLVAKEVEGKKVILPVWHGITREEVQSFSSILANRLAASSEKGIDYVVNEILRVLRKKSV
Protein: Sprouty-related, EVH1 domain-containing protein 1 (Spred-1) (Q924S8)
Organism: Mus musculus (Mouse)
Function: Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase. Negatively regulates hematopoiesis of bone marrow. Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2. Attenuates actin stress fiber formation via inhibition of TESK1-mediated phosphorylation of cofilin (By similarity). Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11493923}; Peripheral membrane protein {ECO:0000269|PubMed:11493923}. Membrane, caveola {ECO:0000269|PubMed:11493923}; Peripheral membrane protein {ECO:0000269|PubMed:11493923}. Nucleus {ECO:0000269|PubMed:11493923}. Note=Localized in cholesterol-rich membrane raft/caveola fractions. {ECO:0000250}.
Interaction partners:
- Neurofibromin
- GTPase HRas
- GTPase KRas
- GTPase NRas
- Sprouty-related, EVH1 domain-containing protein 2
- Phosphatidylinositol 3-kinase regulatory subunit beta
- GTP-binding protein REM 1
- Proteasome subunit beta type-6
- Fibroblast growth factor receptor-like 1
- Ras GTPase-activating protein 1
Sequence:
MSEETATSDNDNSYARVRAVVMTRDDSSGGWLPLGGSGLSSVTVFRVPHQEENGCADFFIRGERLRDKMVVLECMLKKDLIYNKVTPTFHHWKIDDKKFGLTFQSPADARAFDRGIRRAIEDISLGCPASKTEAEGGDDDLQTTEEDTSRSLVKDHFFQQETVVTSEPYRSSDIRPLPFEDLNARRVYLQSQVSQIPFSQQGLDIQSRSMEYVQRQISKECGSLKSQTRVPLKSIRHVSFQDEDEIVRINPRDILIRRYADYRHPDMWKNDLERDDTDSSVPFSKQDSKKSDYLYHCGDETKLSSLKDSVVFKTQPPSLKFKSKRRKEDGERSRCVYCQERFNHEENARGKCQDAPDPVKRCIYQVSCMLCAESMLYHCMSDSEGDFSDPCSCDTSDDKFCLRWLALVALSFIVPCMCCYVPLRMCHRCGEACGCCGGKHKAAG
Protein: Expansin-A4 (AtEXPA4) (Alpha-expansin-4) (At-EXP4) (AtEx4) (Ath-ExpAlpha-1.6) (O48818)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found (By similarity).
Subcellular location: Secreted, cell wall {ECO:0000269|PubMed:9188482}. Membrane {ECO:0000269|PubMed:9188482}; Peripheral membrane protein {ECO:0000269|PubMed:9188482}.
Interaction partners:
- Proline-rich extensin-like family protein
Sequence:
MAIKLAILFTTFVLFSLADARIPGIYSGGAWQNAHATFYGGSDASGTMGGACGYGNLYSQGYGTNTAALSTALFNNGMSCGACFELKCANDPQWCHSGSPSILITATNFCPPNLAQPSDNGGWCNPPREHFDLAMPVFLKIAQYRAGIVPVSYRRVPCRKRGGIRFTINGHRYFNLVLITNVAGAGDIVRASVKGSRTGWMSLSRNWGQNWQSNAVLVGQALSFRVTGSDRRTSTSWNMVPSNWQFGQTFVGKNFRV
Protein: Phenylethanolamine N-methyltransferase (PNMTase) (EC 2.1.1.28) (Noradrenaline N-methyltransferase) (P10937)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the transmethylation of nonepinephrine (noradrenaline) to form epinephrine (adrenaline), using S-adenosyl-L-methionine as the methyl donor (By similarity). Other substrates include phenylethanolamine, octopamine and normetanephrine.
Interaction partners:
- Dopamine beta-hydroxylase
- Catechol O-methyltransferase
- Transmembrane O-methyltransferase homolog
- Amine oxidase [flavin-containing] A
- Amine oxidase [flavin-containing] B
- Tyrosine 3-monooxygenase
- Aromatic-L-amino-acid decarboxylase
Sequence:
MDRGSDPKHTAGMDSDSDPGQAEVALAYQRFEPRAYLRNNYAPPRGDLSNPDGVGPWKLRCMAQVFATGEVSGQVLIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELGLWLREEPGAFDWSVYSQHVCLIEDKGESWQEKERQLRARVKRVLPIDVHKPQPLGASGLAPLPADALVSAFCLEAVSPDLPSFRQALYHITTLLRPGGNLLFIGALEESWYLAGEARLSVVPVSEEEVREALVCSGYEVRDLRTYIMPAHLRTGVDDVKGIFFAWAQKIEVQV
Protein: Arginine ABC transporter permease protein ArtQ (P0AE34)
Organism: Escherichia coli (strain K12)
Function: Part of the ABC transporter complex ArtPIQMJ involved in arginine transport. Probably responsible for the translocation of the substrate across the membrane.
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- Putative ABC transporter arginine-binding protein 2
- ABC transporter arginine-binding protein 1
- Arginine transport ATP-binding protein ArtP
- Arginine ABC transporter permease protein ArtM
- Lysine/arginine/ornithine-binding periplasmic protein
- L-cystine-binding protein TcyJ
- Histidine-binding periplasmic protein
- Glutamine-binding periplasmic protein
- Histidine/lysine/arginine/ornithine transport ATP-binding protein HisP
- L-cystine transport system ATP-binding protein TcyN
Sequence:
MNEFFPLASAAGMTVGLAVCALIVGLALAMFFAVWESAKWRPVAWAGSALVTILRGLPEILVVLFIYFGSSQLLLTLSDGFTINLGFVQIPVQMDIENFDVSPFLCGVIALSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRHALPGLGNQWLVLLKDTALVSLISVNDLMLQTKSIATRTQEPFTWYIVAAAIYLVITLLSQYILKRIDLRATRFERRPS
Protein: Myosin light chain 1 (Q90WC7)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
Sequence:
MAPKKDAKAAPARKPSLQSAAPAPAPEPDVVAAPPALDLSKVKVEFTPDQHEDYKEAFGLFDRVGDSKVAYNQVADIMRALGQNPTNKEVRKVLGNPSDEDMAAKRLEFEAFLPMLQHIVNDPNKGTFDDYVEGLRVFDKEGNGTVMGAELRIVLGTLGEKMSEAEIDGLMQGQEDENGSINFEAFVKHIMSI
Protein: Rab1 (Q67BJ9)
Organism: Trypanosoma brucei
Interaction partners:
Sequence:
MSTEYDHLFKLLLIGDSGVGKSCLLLRFADDSYTESYISTIGVDFKIRTLDIDGKVIKLQIWDTAGQERFRTITSSYYRGAHGIIIVYDTTDMESFNNVKTWLSEIDKFASENVNKLLVGNKCDLVTKKAVDTQMAQEFADSLGIPFLETSAKESSNVETAFIEMAKNIKKRVAAQGANSGATAGGRPLLTGNNRPATNSGGQKSGCC
Protein: OCRE domain-containing protein (Q9CRY1)
Organism: Mus musculus (Mouse)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
TGPMGHTYGFIDLDSHAEALRVVKILQNLDPPFSIDGKMVAVNLATGKRRNDSGDHSDHMHYYQGKKYFRDRRGGNRNSDWSSDTNRQGQQSSSDCYIYDSTTGYYYDPLAGTYYDPNTQQEVYVPQDPESPDEEEIKEKKSTSQGKSNSKKETSKRDGKEKKDRGMTKFQESTSEGKPPLEDVFKKPLPPTVKKEESPPPPKVVNPLIGLLGEYGGDSDYEEEEEEEQAPPVQPRTAQPREEM
Protein: Asator, isoform G (EC 2.7.11.1) (L0MLK2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MFWHLLCVPNDENASAPDDGNQSCQPSSKQDQYLSPNRNCQKNLLRLYPPPPSKPPPLVGAILQTRLLHQISPSAIADADADLNAVGELLYPNVLQRSATLPAKHNRLGVRSRVTFKVPSSNLPAQDSYSHQPRNQVAVAAKDGILVDVKAKESVKMTSEDLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTTGTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWEKVDSTAIGNISATGNPSIPIKSDYMHGNITQMTVAASNASGTEYVDKNCNATSLAQPAKGSGEPMVQHGNAANNQNITSKGLQQQSTLTNSQVAIANIQSAPSMIEREDVQYTKLEEGAPTKFITMKPNGECDNVDIAAKCIFEQKHVEANDDIVGRASLSGVEQHYKSQIKKHNSPEIANKQIQRTGTVTNDKTSEVNRSTEEQKSTFGRLRVLTAPPMSVHDLPSGGGHSHQVSDLSGKQDPYAATSNAAPIGINSSSTKFGSQHGQIFGLAAMPPINRRSATSTNLRPSSSASQRINSGSTIGGAVGNGSNTARSSVAGDHSVTQFALIDDENVSALQQVTKGGALTLASQWKSQFDDSEDTTDNEWNREHQVYRMDIARNVCVRETYSEITHLARPSTSSVLRNRLPSPFKKDSALQLNSTNDSLDKSRHRNSLPNVSVNDIFDDLQMKLNLDLGSAIQENNCCISGRLEIRVIPKDTSHPDDSVYYDAMGAVKNTPTANEGHDHSDQAVNNCDEMEATSAVIAFPNKSISKIMSPPGRDATEERTGASLCSLYSAGVNKLKLNGNTAPRTQFKKGSTDGFGENESEFDFPLLNPSKIPVRQSKCASWAGADFISASKPLESAEVPQEIPYHPQSDTTYSVIDSIPVRKTTYSIALECPPNISDLTPGLSYFYCNIVVPLRLFSILLTES
Protein: FI01813p (Pepsinogen C-like (EC 3.4.23.-)) (Q9W5G3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Uncharacterized protein, isoform B
- V-type proton ATPase subunit a
Sequence:
MPRFQIKSLVFLAGLIVLVGEANSTLRRIPIQKSPNFKRSHKNIVAERDFVQQKYNRQYTANGYPMEHLSNYDNFQYYGNISIGTPGQDFLVQFDTGSSNLWVPGSSCISTACQDHQVFYKNKSSTYVANGTAFSITYGTGSVSGYLSVDCVGFAGLTIQSQTFGEVTTEQGTNFVDAYFDGILGMGFPSLAVDGVTPTFQNMMQQGLVQSPVFSFFLRDNGSVTFYGGELILGGSDPSLYSGSLTYVNVVQAAYWKFQTDYIKVGSTSISTFAQAIADTGTSLIIAPQAQYDQISQLFNANSEGLFECSSTSYPDLIININGVDFKIPAKYYIIEEEDFCSLAIQSINQDFWIMGDVFLGRIYTEFDVGNQRLGFAPVNSAVGLRKAVLWRIFTLLLACGMWKLKN
Protein: Chaperone protein dnaJ A6, chloroplastic (atDjA6) (Chaperone protein dnaJ A26) (AtDjA26) (Q9SJZ7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May function together with HSC70 chaperone to assist protein folding and prevent protein aggregation during heat stress in the chloroplast.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:23894646}.
Interaction partners:
- Heat shock 70 kDa protein 6, chloroplastic
- Heat shock 70 kDa protein 7, chloroplastic
- Chaperone DnaJ-domain superfamily protein
- Pyridoxamine 5'-phosphate oxidase family protein
- Heat shock protein DnaJ with tetratricopeptide repeat-containing protein
- F14D16.11
- Heat shock protein DnaJ with tetratricopeptide repeat-containing protein
- Heat shock 70 kDa protein 15
- Heat shock 70 kDa protein 10, mitochondrial
- Heat shock 70 kDa protein 9, mitochondrial
Sequence:
MAIIQLGSTCVAQWSIRPQFAVRAYYPSRIESTRHQNSSSQVNCLGASKSSMFSHGSLPFLSMTGMSRNMHPPRRGSRFTVRADADYYSVLGVSKNATKAEIKSAYRKLARNYHPDVNKDPGAEEKFKEISNAYEVLSDDEKKSLYDRYGEAGLKGAAGFGNGDFSNPFDLFDSLFEGFGGGMGRGSRSRAVDGQDEYYTLILNFKEAVFGMEKEIEISRLESCGTCEGSGAKPGTKPTKCTTCGGQGQVVSAARTPLGVFQQVMTCSSCNGTGEISTPCGTCSGDGRVRKTKRISLKVPAGVDSGSRLRVRGEGNAGKRGGSPGDLFVVIEVIPDPILKRDDTNILYTCKISYIDAILGTTLKVPTVDGTVDLKVPAGTQPSTTLVMAKKGVPVLNKSNMRGDQLVRVQVEIPKRLSKEEKKLIEELADMSKNKTANSTSR
Protein: S-adenosylmethionine decarboxylase proenzyme (AdoMetDC) (SAMDC) (EC 4.1.1.50) [Cleaved into: S-adenosylmethionine decarboxylase alpha chain; S-adenosylmethionine decarboxylase beta chain] (O02655)
Organism: Caenorhabditis elegans
Function: Essential for biosynthesis of the polyamines spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
Interaction partners:
- PABS domain-containing protein
- Ornithine decarboxylase
- Probable S-adenosylmethionine synthase 1
- Probable S-adenosylmethionine synthase 4
- Probable S-adenosylmethionine synthase 5
- Probable S-adenosylmethionine synthase 3
- Arginase
- Trifunctional purine biosynthetic protein adenosine-3
- Major facilitator superfamily
- Dihydroorotate dehydrogenase
Sequence:
MSATSATNFAVQTHPVKAPDEEYFFEGAEKLLELWFCSSTQNETRSLRIIPREEIDAMLDIARCKILHSKHNESIDSYVLSESSLFISDNRVILKTCGTTRLLAALPVIMQLAGAYAGLDQVQSVYYSRKNFLRPDLQPSLHKNFDAEVEYLDSFFVDGHAYCLGSLKQDRWYLYTFHREVEFPAHKQPDHTLEILMSDLDEEVLHKFTKDYAVDGNDCFMRAGIDKIIPAGADVHDELFDPCGYSMNAYMNDTDQYATIHVTPEKAFSFASFETNQDLVCLYSQTRKVLQCFRPNKILMTVFANDISEKGKDAQQQLWDRELPGYRRTNVQFVRLETETLVYAHFVRKASTGQDSSSSDEDDGERSD
Protein: Ethylene-responsive transcription factor ERF053 (AtERF53) (Q9SKT1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional activator involved in abiotic stress tolerance. Can directly regulate stress-related gene expression by binding to the DNA sequence 5'-[AG]CCGAC-3' (DRE element) of their promoter region. Involved in the regulation of stomatal closure movement under drought stress. Acts as a positive regulator of drought stress response.
Subcellular location: Nucleus {ECO:0000269|PubMed:22095047}.
Interaction partners:
- E3 ubiquitin-protein ligase RGLG2
- E3 ubiquitin-protein ligase RGLG1
- Nucleic-acid protein
- E3 ubiquitin protein ligase DRIP1
Sequence:
MATAKNKGKSIRVLGTSEAEKKDEMELEEEFQFSSGKYKDSGPGSDMWLGDASSTSPRSLRKTRTFDRHNPYLVSSYATPQPPTTTTCSVSFPFYLPPAIQNQQRFLHPNDPSGQRQQQMISFDPQQQVQPYVAQQQQQQQHLLQYWRDILKLSPSGRMMMMNMLRQESDLPLTRPPVQPFSATKLYRGVRQRHWGKWVAEIRKPRNRTRLWLGTFDTAEEAAMAYDREAFKLRGETARLNFPELFLNKQEPTPVHQKQCETGTTSEDSSRRGEDDSSTALAVGGVSEETGWAEAWFNAIPEEWGPGSPLWDDYHFPISNHKDDLDATQNSSSDTI
Protein: Growth arrest and DNA damage-inducible protein GADD45 beta (Myeloid differentiation primary response protein MyD118) (Negative growth regulatory protein MyD118) (P22339)
Organism: Mus musculus (Mouse)
Function: Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK (By similarity).
Interaction partners:
- Mitogen-activated protein kinase kinase kinase 4
- Cyclin-dependent kinase 1
- Cellular tumor antigen p53
- G2/mitotic-specific cyclin-B1
- Growth arrest and DNA damage-inducible protein GADD45 alpha
- Growth arrest and DNA damage-inducible protein GADD45 gamma
- G2/mitotic-specific cyclin-B2
- Proliferating cell nuclear antigen
- G2/mitotic-specific cyclin-B3
- Dual specificity mitogen-activated protein kinase kinase 7
Sequence:
MTLEELVASDNAVQKMQAVTAAVEQLLVAAQRQDRLTVGVYEAAKLMNVDPDSVVLCLLAIDEEEEDDIALQIHFTLIQSFCCDNDIDIVRVSGMQRLAQLLGEPAETLGTTEARDLHCLLVTNCHTDSWKSQGLVEVASYCEESRGNNQWVPYISLEER