wanglab/gogpt-training-data huggingface dataset:
Protein: Pyruvylated Gal-beta-1,3-epitope synthesis protein 2 (PvGal synthesis protein 2) (Meiotically up-regulated gene 53 protein) (O14001)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in cell wall biogenesis. Has a role in the addition of Gal-beta1,3 moeities to galactomannans and their subsequent pyruvylation. Has a role in meiosis.
Subcellular location: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Note=Recycles between endoplasmic reticulum and Golgi. {ECO:0000305}.
Interaction partners:
- Beta-1,3-galactosyltransferase pvg3
- UDP-glucose 4-epimerase uge1
- Pyruvylated Gal-beta-1,3-epitope synthesis protein 5
- UDP-galactose transporter
Sequence:
MTKLWVNFFSQKLLRLLIPSIIVVFAFAALFAIYSPIQLGGINFYKRTNLFTVEELGEKELELSKTVTIDIYRKAMCMDDLEQSRKCTTFGLDPPISAHLFYTYNRDTGMNRVARQWNRRIPRVFHTIKGSNFIELSQFTAFEVELRVSHPNWAFVSWSHDDLNELVDKSYHNLHNAWSQLSREAKDQWGFLLGLYEYGGVWMSRSLQLKKNIDKFVYAAELSVKQFTENITSSTVEEFQPIFMAPKSLQYDFMIATPKHPFVLSLINELCKSEVLLKILSKRPYHGLDAAEALFAENRESITIREQEFFVNTYIDDGKVFVKNNPHIIFIPTEAFASTWDFLPSEESSEMCFADSPLFDPDYCISHSSKPDGNELAIYWSNSFDLITA
Protein: Involucrin (P48997)
Organism: Mus musculus (Mouse)
Function: Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.
Subcellular location: Cytoplasm. Note=Constituent of the scaffolding of the cornified envelope.
Interaction partners:
- Loricrin
- Filaggrin
- Keratin, type I cytoskeletal 10
- Protein-glutamine gamma-glutamyltransferase K
- Keratin, type II cytoskeletal 1
- Periplakin
- Keratin, type I cytoskeletal 14
Sequence:
MSHQHTLPVTVPAVVQGPLKTVCSPDHIQQEQAKQPTPHPTQCQVFTEIQEKGFPKHEEKRPNPVKDLPDQKCEHQQQPGPQKQQLQVKKSQQELQEQELHLEKQQLPQEPQGLLCLEQQQQQEPQMQEQHLRQQQQQQQQQQQQQQQQQQQETQEQGLCLGQKQQQQQQDMLVPQELHLRQHQEKLQDPELHLGQQQKTPEEQKLIPGEKQQELHLGQRHQEPQEQELHLGQKQKQKLHEPELQLGKQQHQKPSEPELPLGKQQQESPEPELPLGKQQQQESPEPELQLGKQQQSHEPDMAGDQKEKQKLHKPELYLRKQQYQESPDPELSLGKQQHQECQEPELQLEEKQHQKPPEPELHLGKQQESHEPDMAEDLEEKQKLGEPELHLGKQQQQQIEREGYQGPKSLGQSLKQEKASREQQLDYSHLEQEKELSDQPLDQALVKKGKQLERKKHELENRTQQEK
Protein: Pancreatic triacylglycerol lipase (PL) (Pancreatic lipase) (EC 3.1.1.3) (P27657)
Organism: Rattus norvegicus (Rat)
Function: Plays an important role in fat metabolism. It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones.
Subcellular location: Secreted {ECO:0000305|PubMed:8203536}.
Interaction partners:
- Colipase
- Bile salt-activated lipase
- Chymotrypsin-like elastase family member 2A
- Chymotrypsinogen B
- Carboxypeptidase A1
- Carboxypeptidase B
- Gastric triacylglycerol lipase
- Inactive pancreatic lipase-related protein 1
- Chymotrypsin like elastase 3B
- Pancreatic lipase-related protein 2
Sequence:
MLMLWTFAVLLGAVAGKEVCFDKLGCFSDDAPWSGTIDRPLKALPWSPAQINTRFLLYTNENQDNYQKITSDASSIRNSNFKTNRKTRIIIHGFIDKGEENWLSDMCKNMFKVESVNCICVDWKGGSRATYTQATQNVRVVGAEVALLVNVLKSDLGHPPDNVHLIGHSLGSHVAGEAGKRTFGAIGRITGLDAAEPYFQGTPEEVRLDPTDAQFVDAIHTDAAPIIPNLGFGMSQTVGHLDFFPNGGMEMPGCQKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIVNPTGFSGFSCSSYNVFSANKCFPCGSEGCPQMGHYADKYPGKTKELYQKFYLNTGDKSNFARWRYQVTVTLSGQKVTGHILVSLFGNGGNSKQYEVFKGSLHPGDTHVKEFDSDMDVGDLQKVKFIWYNNVINPTLPKVGASRISVERNDGRVFNFCSQDTVREDVLLTLSAC
Protein: Malignant fibrous histiocytoma-amplified sequence 1 (Malignant fibrous histiocytoma-amplified sequence with leucine-rich tandem repeats 1) (Q9Y4C4)
Organism: Homo sapiens (Human)
Function: Probable GTP-binding protein. Functions in innate immunity and more specifically the inflammatory response as a regulator of the Toll-like receptor TLR2 and TLR4 signaling pathways. Negatively regulates the part of the TLR4 signaling pathway that leads to the activation of the transcription factor AP-1. By retaining the phosphatase complex PP2A into the cytoplasm, prevents the dephosphorylation of the AP-1 subunit JUN which is required for proper activation of the transcription factor. Both inhibits and activates the TLR2-dependent signaling pathway. Positively regulates the TLR2 signaling pathway to activate specifically the downstream p38 and JNK MAP kinases and promote the polarization of macrophages toward the pro-inflammatory M1 phenotype. It may also play a role in the regulation of inflammation induced by high glucose through the PKB/AKT signaling pathway. Also involved in erythrocyte differentiation through activation of the ERK1/ERK2 signaling pathway.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:24286120}.
Interaction partners:
- Claudin-23
- Protein phosphatase 1 regulatory subunit 3B
- E3 ubiquitin-protein ligase Praja-2
Sequence:
MAGMDSGNLKTARLWRDAALRARKLRSNLRQLTLTAAGACPGAGADALESPASPQLVLPANLGDIEALNLGNNGLEEVPEGLGSALGSLRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIAVLPDHFGQLSRVGLWKIKDNPLIQPPYEVCMKGIPYIAAYQKELAHSQPAVQPRLKLLLMGHKAAGKTLLRHCLTEERVEGCPGGGDKEKCYPPSPPPVSKGIEVTSWTADASRGLRFIVYDLAGDESYEVIQPFFLSPGALYVLVVNLATYEPRHFPTTVGSFLHRVGARVPHAVVCIVGTHADLCGERELEEKCLDIHRQIALQEKHDAEGLSRLAKVVDEALARDFELRSASPHAAYYGVSDKNLRRRKAHFQYLLNHRLQILSPVLPVSCRDPRHLRRLRDKLLSVAEHREIFPNLHRVLPRSWQVLEELHFQPPQAQRLWLSWWDSARLGLQAGLTEDRLQSALSYLHESGKLLYFEDSPALKEHVFHNLTRLIDILNVFFQRDPSLLLHKLLLGTSGEGKAEGESSPPMARSTPSQELLRATQLHQYVEGFLLHGLLPAHVIRLLLKPHVQAQQDLQLLLELLEKMGLCYCLNKPKGKPLNGSTAWYKFPCYVQNEVPHAEAWINGTNLAGQSFVAEQLQIEYSFPFTFPLGLFARYSVQINSHVVHRSDGKFQIFAYRGKVPVVVSYRPARGVLQPDTLSIASHASLPNIWTAWQAITPLVEELNVLLQEWPGLHYTVHILCSKCLKRGSPNPHAFPGELLSQPRPEGVAEIICPKNGSERVNVALVYPPTPTVISPCSKKNVGEKHRNQ
Protein: Mitochondrial intermediate peptidase (MIP) (EC 3.4.24.59) (A6H611)
Organism: Mus musculus (Mouse)
Function: Cleaves proteins, imported into the mitochondrion, to their mature size.
Subcellular location: Mitochondrion matrix {ECO:0000250}.
Interaction partners:
- Mitochondrial-processing peptidase subunit alpha
- Xaa-Pro aminopeptidase 3
- Mitochondrial inner membrane protease subunit 2
- Mitochondrial-processing peptidase subunit beta
Sequence:
MLLAAGARYARRLCGRGAAAALQGRTGRSCARDVSTSWSPVGAAFNVKPQSHLWNLLGERRGLFGVPELSTPEGFQVAQEEALKKTEWLVERACSTPPGPQTVLIFDELSDCLCRVADLADFVKIGHPDPAFREAAQEACRSIGTMVEKLNTNVELYQSLQRLLGDKKLMESLDAETRRVAELFMFDFEISGIHLDEEKRRRAVDLNVKILDLSNAFLMRTNFPNKIRKSLLPEHIQHHFARDGSHLIIDGLHAEASDDLVREAAYKIFLYPNADQLKCLEELLSSRDLLAKLVGYSTFSHRALQGTIAQTPETVMQFLEKLSEKLSERTRKDFKMMQGMKTKLNPQNSKLMPWDPPYYSGVIRAERYNIEPSLYCPFLSLGACMEGLNVLFNKLLGITLYAEQTFKGEVWCNDIRKLAVVHESEGLLGYIYCDFFQRANKPQQDCHFTIRGGRLKEDGSYQLPVVVLMLNLPHASRDFPTLLTPGMMENLFHEMGHAMHSMLGRTRYQHVTGTRCPTDFAEVPSILMEYFSNDYRVVSQFAKHYQTGQPLPKAMVSRLCESKKVCTAAEMQLQVFYAALDQIYHGQHPLKKSTTDILMETQEQFYGLPYVPDTAWQLRFSHLVGYGAKYYSYLMSRAVASMIWKECFLQDPFNRAAGERYRREMLAHGGGKEPMLMIQGMLQKCPSIDDFVDALVSDMNLDFETFFLDSK
Protein: O-acyltransferase (Q0QJI1)
Organism: Vernicia fordii (Tung) (Aleurites fordii)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|PIRNR:PIRNR000439}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|PIRNR:PIRNR000439}.
Interaction partners:
Sequence:
MTIPETPDNSTDATTSGGAESSSDLNLSLRRRRTASNSDGAVAELASKIDELESDAGGGQVIKDPGAEMDSGTLKSNGKDCGTVKDRIENRENRGGSDVKFTYRPSVPAHRALKESPLSSDNIFKQSHAGLFNLCIVVLVAVNSRLIIENIMKYGWLIKTGFWFSSRSLRDWPLLMCCLTLPIFSLAAYLVEKLACRKYISAPTVVFLHILFSSTAVLYPVSVILSCESAVLSGVALMLFACIVWLKLVSYAHTNFDMRAIANSVDKGDALSNASSAESSHDVSFKSLVYFMVAPTLCYQPSYPRTASIRKGWVVRQFVKLIIFTGFMGFIIEQYINPIVQNSQHPLKGDLLYAIERVLKLSVPNLYVWLCMFYCFFHLWLNILAELLRFGDREFYKDWWNARTVEEYWRMWNMPVHKWMVRHIYFPCLRHKIPRGVALLITFFVSAVFHELCIAVPCHIFKLWAFIGIMFQIPLVGITNYLQNKFRSSMVGNMIFWFIFCILGQPMCLLLYYHDLMNRKGTTESR
Protein: GM06507p (Q95S79)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MSIKCVHLVGLLVLLMGGANALFDHTLKRDFPGPYCARENTCCKDRHDGCSVPISNTLCYCDEFCDRDDSSDCCPDYRSFCIGEVDPIISCEHNGVYFSKYNTTWDNCNECRCLEGGSVQCDEDLCLTDDAIVHSVNSIHRLGWSARKYDQWWGRKYSEGLKLRLGTKEPTYRVKAMTRLKNPTDGLPNSFNALDKWSSYISEVPDQGWCGASWVLSTTSVASDRFAIQSKGKENVQLSAQNILSCTRRQQGCEGGHLDAAWRYLHKKGVVDENCYPYTQHRDTCKIRHSRSLKANGCQKPVNVDRDSLYTVGPAYSLNREADIMAEIFHSGPVQATMRVNRDFFAYSGGVYRETAANRKAPTGFHSVKLVGWGEEHNGEKYWIAANSWGSWWGEHGYFRILRGSNECGIEEYVLASWPYVYSYYNVKSA
Protein: Multidrug resistant protein (Q8NKG7)
Organism: Hapsidospora chrysogena (Acremonium chrysogenum)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MANNSGTTTVQLDDVLERSSTLNTLNNIDTVQHHEPRTSFANNRQQAPAGGSSQSDATVGPRHKLVTFAPDDPENPKNWSKAYKWYCTLVVSLTCFVVAFASSVISADIDGVMEEFNVSETAALVSISVFVVGFGVGPMVFAPLSEVYGRRIIYGSKLLFAVIFVIPCAVSKNLGTLLACRAIDGIAFSAPMTLVGGTLADMWKNEERGVPMAAFSAAPFAGPAIGPLVGGYLSDAAGWRWLYWIQLILSGIIWILITFTVPETYAPTILAKRARKLRKSTGDPNHVTEQELDPRPISEQLRVFLTRPFQLLFGELIVLLISLYMSVLYGLLYMFFIAYPIVYKGGKGYSSGKTGLMFIPVAVGVVLSACCSPFVNTHYISLAHFHGGKPPAEVRLIPMMLSCWLIPIGLFIFAWTSYPWLSWAGPAMGGFPVGFGFIFLYNSANNYLVDSYQHQAASALAAKTFIRSFWGAGVVLFTKQMYSRLGDQWASSLIAFLALACCAIPFLFWKYGARIRARSKYAYAGDETPADVEKAKQRPAEAGVLADADDLRRAISYVSNP
Protein: Photosystem II reaction center protein J (PSII-J) (Q2LIK4)
Organism: Oryza latifolia
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000256|HAMAP-Rule:MF_01305}; Single-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_01305}.
Interaction partners:
Sequence:
MADTTGRIPLWLIGTVTGIAVIGLIGVFFYGSYSGLGSSL
Protein: Serine/threonine protein kinase PK9 (EC 2.7.11.1) (Q8IEG4)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- Protein phosphatase PPM5, putative
Sequence:
MYLGSIKNFEDDFLCKGEYKQVYLSLEQNENNEAIEIDICCDNNIYDILQFCREKYGIYGEYIIDSCGNVIHSIKDIIDGDTLYLKEKKEDMNFFSKIKNNFIVNDYIVEKRIGSGGFGIVFQGVHIQTKQKVALKFIPKSNFLDVTDVHRVFIEIQTLRGLIHNNIIKMYDVNHFQNYVCLIMEYAINGDLKNYIKNKFNGFLSEKEAHDLFLQIVKGVYYCHSKHIVHRDLKLENILLDEKMTCKIADFGLSDFVNVDQNIKTEAGTKAYIAPEIIFNQTINYSVFKLDIWSLGILLFIMTQGFAPFKYMEKELKNFESNTLNYANDISDDLKDLISLMLNVDPNKRPIIVEILNHRWFENYKES
Protein: Glutamate decarboxylase 1 (EC 4.1.1.15) (67 kDa glutamic acid decarboxylase) (GAD-67) (Glutamate decarboxylase 67 kDa isoform) (P48318)
Organism: Mus musculus (Mouse)
Function: Catalyzes the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor.
Interaction partners:
- Glutamate decarboxylase 2
- 4-aminobutyrate aminotransferase, mitochondrial
- Vesicular inhibitory amino acid transporter
- Glutamine synthetase
- Glutaminase liver isoform, mitochondrial
- Glutaminase kidney isoform, mitochondrial
- Methyl-CpG-binding protein 2
- Glutamate dehydrogenase 1, mitochondrial
- Parvalbumin alpha
- Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
Sequence:
MASSTPSPATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEKSRLVSAFRERQSSKNLLSCENSDQGARFRRTETDFSNLFAQDLLPAKNGEEQTAQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWSNKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVPKLVLFTSEHSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADLEAKILDAKQKGYVPLYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRHKLSGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELADYLYAKIKNREEFEMVFDGEPEHTNVCFWYIPQSLRGVPDSPERREKLHRVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL
Protein: Pseudouridine synthase (EC 5.4.99.-) (F4KBV6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MKRKQQEDDNDDGVEKAVSPVLATTSNTMSTDLLLQSSSKLSQKQDYIFHGGRRHVRPYYFEFISHVNKRWTGKTIVDLFADEFKGRPRDYYVGAVKSGRIKVDGEIVPVSYIVKSSQKITHFLHRHEPPVMIDDVVILHQEPDVVTVCKPASVPVHPCGQYRKNTIVGILDAEHDLGTLFPIHRLDRLVSGLLIIARTAAKADFFRQQIEGGMVKKRYIAKVIGVFPEDEMIVDANINYNGSEGRSTAEDANSSGDDKKVKGKPACTKFTRIDTNGTHSLVSCEPVTGRTHQIRVHLQYTGHPIANDPLYLNQHIDNLETYIAKRIDAGERKIVSPDDYVYSSEDFSIDPMCTNCPKLIPQGYEEHDEALWLHCVQYCGTGWEYEWYQVDSLYSKILSFIDSKFYVIII
Protein: Heat shock protein sti1 homolog (Q9USI5)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: May play a role in mediating the heat shock response of some HSP70 genes.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Heat shock protein 90 homolog
- Uncharacterized protein C1711.08
- Heat shock protein homolog pss1
- Heat shock protein 104
- 40 kDa peptidyl-prolyl cis-trans isomerase
- Probable heat shock protein ssa2
- Hsp90 co-chaperone Cdc37
- Probable heat shock protein ssa1
- Heat shock protein 78
- Protein psi1
Sequence:
MAEELKAKGNAAFSKKDYKTAIDYFTQAIGLDERNHILYSNRSACYASEKDYADALKDATKCTELKPDWAKGWSRKGAALHGLGDLDAARSAYEEGLKHDANNAQLLNGLKSVEAAQTQAASGAGGFNPFAKLGSQLSDPKFMEKLASNPETASLLADSAFMAKLQKIQQNPGSIMAELNDPRMMKVIGMLMGIDINMNAGEGAAEEQEKKEEFAPSSSTPSADSAKPETTNPPPQPQASEPMEEDKTAEELEEAATKEALKKKADQEKQIGNENYKKRNFPVAIEQYKKAWDTYKDITYLNNLAAAYFEADQLDDCIKTCEDAIEQGRELRADFKLIAKALGRLGTTYQKRGDLVKAIDYYQRSLTEHRTPDILSRLKDAEKSKELQDREAYIDPDKAEESRVKGNELFKSGDFANAIKEYTEMTKRAPSDPRGFGNRAAAYLKVMAPAECIRDCNKAIELDPNFAKAYVRKAQALFMLKDYNKCIDACNEASEVDRREPNTGKNLREIESQLSKCMSAMASQRQNETEEETMARIQKDPEVLGILQDPAMQAILGQARENPAALMEHMKNPTVKSKIEKLIASGVIRLG
Protein: Lysine-specific demethylase JMJ32 (EC 1.14.11.68) (Jumonji domain-containing protein 32) (AtJMJ32) (Protein JUMONJI 32) (Lysine-specific histone demethylase JMJ32) ([histone H3]-trimethyl-L-lysine(27) monodemethylase JMJ32) (Q0WVR4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Histone demethylase that demethylates 'Lys-27' (H3K27me) of histone H3 with a specific activity for H3K27me3 and H3K27me2, and involved in the regulation of gene expression. No activity on H3K27me1. Together with JMJ30, regulates the flowering-repressor FLOWERING LOCUS C (FLC) locus by removing the repressive histone modification H3 lysine 27 trimethylation (H3K27me3), especially at elevated temperatures (e.g. 29 degrees Celsius), thus preventing extreme precocious flowering. JMJ30 and JMJ32 are regulators involved in the integration of abscisic acid (ABA) and brassinosteroids (BR) signaling pathways. Together with JMJ30, controls ABA-mediated growth arrest during the post-germination stage in unfavorable conditions, and responses to ABA during root development, via the removal of repressive histone mark (H3K27me3) from the SnRK2.8 promoter, thus promoting SnRK2.8 expression and subsequent kinase-dependent ABI3 activation. In addition, removes the repressive histone marks (H3K27me3) from the BZR1 locus in response to stress and ABA, thus activating the BR signaling pathway which, in turn, inhibits the ABA signaling pathway.
Subcellular location: Nucleus {ECO:0000269|PubMed:25267112}. Cytoplasm {ECO:0000269|PubMed:25267112}. Endoplasmic reticulum {ECO:0000269|PubMed:25267112}. Note=Predominantly localized in the nucleus. {ECO:0000269|PubMed:25267112}.
Interaction partners:
- Lysine-specific demethylase ELF6
- Lysine-specific demethylase REF6
- Cytosolic sulfotransferase 9
- Auxin-responsive protein SAUR26
- Serine/threonine-protein kinase SRK2C
- 17.6 kDa class I heat shock protein 3
Sequence:
MAKEIENLWREVRELSLGTKIDRFDSQPSPVKFLRNYVSQSKPCVISKAITHWPALKLWSDPAYLTGALSDDVVSLHLTPNGCADAVTGDSDLCFASAHVEKVLFPEALKVVQSSCKGLKVGYLQQQNDCFRTEYSTVALDCDGDIEWATEAFGCSPEAVNLWIGTDDSVTSFHKDHYENLYAVVSGEKHFLLLPPTDVHRLYIEQYPAANYSYHRDTDAFKLEVEEPVRHVPWSSVDPYPSPEKEASERLKFPLFFDGPKPFHCTVKAGEVLYLPSMWFHHVSQTPGDGGYTIAVNYWYDMQFDIKYAYFNFLQSLLYKSSSLNPVLSWREDEDSESSDAEIAP
Protein: Calcium uniporter protein 1, mitochondrial (AtMCU1) (F4I111)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:28031475}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Calcium uptake protein, mitochondrial
- Preprotein translocase Sec, Sec61-beta subunit protein
- Pectinesterase QRT1
- Autophagy-related protein 18b
- Autophagy-related protein 13b
- Autophagy-related protein 8d
- Vacuolar-processing enzyme alpha-isozyme
Sequence:
MWSMGLIRRTAMSNAIRASSQRTWLGHGGLRSCVTVKTPSEDEEEKKKEITIAEAKKLMRLVNVEDMKKKLVGVADRDVVSYSTLLEASQGMGIARSPDEAHVFARVLDDAGVVLIFRDKVYLHPDKVVDLIRRAMPLDQNPEEDQIKEEFNKLRIMKEEIDVLAHRQVRKILWCGLATSMVQIGLFFRLTFWEFSWDVMEPITFFATATGIIVGYAYFLMTSRDPTYQDFMKRLFLSRQRKLLKSHKFDCERFKELERLFKMTSSCHAAASIRNRVGLELDLEDALQSRRD
Protein: Conserved hypothetical prophage protein (D2TRA0)
Organism: Citrobacter rodentium (strain ICC168) (Citrobacter freundii biotype 4280)
Interaction partners:
- Phage tail protein
- Phage tail spike protein
- Conserved hypothetical prophage protein
- Phage tail protein
- Phage baseplate protein
- Phage baseplate protein
- Phage tail protein
- Phage tail tube protein
- Phage tail fibre protein
- Phage tail sheath protein
Sequence:
MSQTQTEAEIFTLKYPFTTAAGNSIAQLTLNRLTVKDLKQIKKTHKNPTDWDEPLISRSTGLLPEDLDNMDLADYLELQDRFQKITGLGKKHDSADKGAGAAGEVVPVPAGGD
Protein: Cathepsin B-like cysteine proteinase 3 (EC 3.4.22.-) (Cysteine protease-related 3) (P43507)
Organism: Caenorhabditis elegans
Interaction partners:
- Aspartic protease 3
- Aspartic protease 4
- legumain
- Neprilysin-2
- Actin
- Neprilysin-1
Sequence:
MLKVYFLALFLAGCSAFVLDEIRGINIGQSPQKVLVDHVNTVQTSWVAEHNEISEFEMKFKVMDVKFAEPLEKDSDVASELFVRGEIVPEPLPDTFDAREKWPDCNTIKLIRNQATCGSCWAFGAAEVISDRVCIQSNGTQQPVISVEDILSCCGTTCGYGCKGGYSIEALRFWASSGAVTGGDYGGHGCMPYSFAPCTKNCPESTTPSCKTTCQSSYKTEEYKKDKHYGASAYKVTTTKSVTEIQTEIYHYGPVEASYKVYEDFYHYKSGVYHYTSGKLVGGHAVKIIGWGVENGVDYWLIANSWGTSFGEKGFFKIRRGTNECQIEGNVVAGIAKLGTHSETYEDDGGAATSCSFIMCTLMVLTYYFV
Protein: Urea transporter DVU1160 (dvUT) (Q72CX3)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Function: Urea channel that facilitates transmembrane urea transport down a concentration gradient.
Subcellular location: Cell membrane {ECO:0000269|PubMed:19865084}; Multi-pass membrane protein {ECO:0000269|PubMed:19865084}.
Interaction partners:
- Membrane protein, putaive
Sequence:
MFGEQLLKNPLIEFCDSVCRGCGQVMFQNNTVTGLLFFAGIFYNSTTLGVCAVLGTAASTLTAQLLGVDKPLVRAGLFGFNGTLAGIALPFFFNYEPAMLGYVALNGAFTTIIMASLLNFLGKWGVPALTAPFVLATWLLMFGVYKLSLFHPGALIAPALPSVAGLADMGTVTGRTFMEGLFKGVGEVMFQDNIVTGVIFVVAILVNSRISALFAVIGSLVGLCTALIMHSPETPVRLGLYGFNSVLCGIAMGGIFFYLNIRTFLYALGCMVLGAIATGAFSVLLSPIGMPALTWPFIVVTWLFLFAGSMFRNIAQVPTEKAGTPEDNLRSLAIGSR
Protein: Cellulose synthase-like protein D1 (AtCslD1) (EC 2.4.1.-) (O49323)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Thought to be a Golgi-localized beta-glycan synthase that polymerize the backbones of noncellulosic polysaccharides (hemicelluloses) of plant cell wall.
Subcellular location: Golgi apparatus membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Glucomannan 4-beta-mannosyltransferase 7
- Probable galacturonosyltransferase 13
- Probable galacturonosyltransferase 14
- At1g29770
- Probable pectinesterase 48
- Pectinesterase PPME1
- Probable xyloglucan glycosyltransferase 6
- Glycosyltransferase
- Pectinesterase 4
- Pectinesterase 5
Sequence:
MASSPPKKTLNSQSSSLSRPPQAVKFGRRTSSGRIVSLSRDDDMDVSGDYSGQNDYINYTVLMPPTPDNQPAGSSGSTSESKGDANRGGGGGDGPKMGNKLERRLSVMKSNNKSMLLRSQTGDFDHNRWLFESKGKYGIGNAFWSEEDDTYDGGVSKSDFLDKPWKPLTRKVQIPAKILSPYRLLIVIRLVIVFFFLWWRITNPNEDAMWLWGLSIVCEIWFAFSWILDILPKLNPINRATDLAALHDKFEQPSPSNPTGRSDLPGVDVFVSTADPEKEPPLVTANTLLSILAVDYPIEKLSAYISDDGGAILTFEAMAEAVRFAEYWVPFCRKHDIEPRNPDSYFSIKKDPTKNKKRQDFVKDRRWIKREYDEFKVRINGLPEQIKKRAEQFNMREELKEKRIAREKNGGVLPPDGVEVVKATWMADGTHWPGTWFEPKPDHSKGDHAGILQIMSKVPDLEPVMGGPNEGALDFTGIDIRVPMFAYVSREKRPGFDHNKKAGAMNGMVRASAILSNGAFILNLDCDHYIYNSKAIKEGMCFMMDRGGDRICYIQFPQRFEGIDPSDRYANHNTVFFDGNMRALDGLQGPVYVGTGCMFRRYALYGFNPPRANEYSGVFGQEKAPAMHVRTQSQASQTSQASDLESDTQPLNDDPDLGLPKKFGNSTMFTDTIPVAEYQGRPLADHMSVKNGRPPGALLLPRPPLDAPTVAEAIAVISCWYEDNTEWGDRIGWIYGSVTEDVVTGYRMHNRGWRSVYCITKRDAFRGTAPINLTDRLHQVLRWATGSVEIFFSKNNAMFATRRLKFLQRVAYLNVGIYPFTSIFLVVYCFLPALCLFSGKFIVQSLDIHFLSYLLCITVTLTLISLLEVKWSGIGLEEWWRNEQFWLIGGTSAHLAAVVQGLLKVIAGIEISFTLTSKASGEDEDDIFADLYIVKWTGLFIMPLTIIIVNLVAIVIGASRTIYSVIPQWGKLMGGIFFSLWVLTHMYPFAKGLMGRRGKVPTIVYVWSGLVSITVSLLWITISPPDDVSGSGGISV
Protein: Pro-neuropeptide Y [Cleaved into: Neuropeptide Y (Neuropeptide tyrosine) (NPY); C-flanking peptide of NPY (CPON)] (Q9I8P3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
Subcellular location: Secreted.
Interaction partners:
- Neuropeptide Y receptor type 2
- Pro-opiomelanocortin protein
- Neuropeptide Y receptor type 2
- Agouti-related neuropeptide.
- Neuropeptide Y receptor Y4
- Neuropeptide Y receptor type 1
- Neuropeptide Y receptor Y2
- Peptide YY-A
- Neuropeptide Y /peptide YY receptor Yb
- Appetite-regulating hormone isoform X1
Sequence:
MNPNMKMWMSWAACAFLLFVCLGTLTEGYPTKPDNPGEDAPAEELAKYYSALRHYINLITRQRYGKRSSADTLISDLLIGETESRPQTRYEDHLAW
Protein: UT01249p (Q5BIM0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MQRARLLRNVWLCRQRLGHLPGRSASSASLAFRYATKPAAPAVPFSLLQMRSLGTGGVLSAVERRSRRPASSSEKPKASVADAWTQLEAYYRQHDLINFEHCQRLLELLQESASPLGVGIEEVHFLLGSCVPELLPAQSSQERLQLFKGLWAQLIKLGQPTLAHYHTKLQVLRQNRLPLTDYRSLLAEIAVYHGAADSTLYGALLDVAGAAGNMRMATEILSEMRERSLALTEHNFHALLLGHARSGDLPGAESVLASMRAAGIQQGSSTQAIWFEALVENGQLAQAKELLQVEHGFTAPQLLQMLRGLLASKDVDTDLIQLLVKELPREFLTGIDLPPAIRSLCIQLVHQGRTEVVIQLVGALPAPKFELQNQNVDEYGALLLQEFFRAQVPLDQTIQFAGQLVQRNQNVRALHLVAELALRRQPSSALRCLEDLSAAGEELRPHYFWPLILHHYRREGESGMLRLVSEMRRLRVECDEETLRHYLFPHLRQTLVQPLEAVKALESAGVKPSQTLCPVVSHLLQQHQMSEVLDLLDRYPTRLDLATLLQPLSSLAVNARATKRFEVFAKVIQALQQKALKRGEDFVGSLLLQMTGPQTRLRQDATSLRRFLHELRRLELQISPAASEALLSVVRHATDDVDLIQDLAKTLQKMKNPQLALPADTVSLHGGFIKHPRDMSIDELECHLVELESKQLNPRGVLRRLLQLSVRSGRLERAQQLLAKCQVLKVQESAGMMASIFDLHIKLRDLPRAQESLERLSSMYPAFQIDEHKVIDYAALLVQGQQLEAAKQLLQRRAEQHKVVGGDYVMKNVWQLLTNVGQLAASSHAGGESSKQLNQTREWLDFLRGLGYCQSQNALLGPVVREWLLKGNLDAAVAEFQRLANTHKHTPLQFELLSLLVRLGNGDEQELTRFPGVTAESAQQHLAAVTATVSRIHGAANMNSALLLALAESGKETQLRRLIINPEFRINHELLVKNCEHLGQEGAVRTLLRLARGVRGVQRTIDEQKIYDLLLAQFCRSNDYEAALDLFERLEADDELKVSHEFLRNLVQLLQVNQVEIPSTIALRAHVR
Protein: POLG alternative reading frame (POLGARF) (ORF-Y) [Cleaved into: POLGARF C-terminal fragment (POLGARFin)] (A0A3B3IS91)
Organism: Homo sapiens (Human)
Subcellular location: [POLG alternative reading frame]: Nucleus, nucleolus {ECO:0000269|PubMed:32958672}.; SUBCELLULAR LOCATION: [POLGARF C-terminal fragment]: Secreted {ECO:0000269|PubMed:32958672}.
Interaction partners:
Sequence:
MEPKARCSDSQRGGPCTNHEPPALEEGGRRHRRARAGSSSGALGLQLRPRVRPQRRAAAAAAAAAAAAAAATAASAAASAILGGRAAAAQPIGHPDALERAARANLRARRGDAWRGRGAPQRRAPAEARALGAASRALARRGAAPAAPLRGQPGPALPPPGPEAEPALPGGGQLAVAGPAAPEAPGLGLGGGLDPVRPRGGGRTRGHPRGAGPGVRRGGLLGRGNLPHIGGGHIPLGLVFLVQPAAGGRALLLDQPAVAG