wanglab/gogpt-training-data huggingface dataset:
Protein: Small ribosomal subunit protein bS1m (37S ribosomal protein MRP51, mitochondrial) (Q02950)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane. bS1m functionally interacts with the 5'-UTR of mitochondrial mRNAs.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14576278, ECO:0000269|PubMed:9528754}. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1. {ECO:0000269|PubMed:25609543}.
Interaction partners:
- Small ribosomal subunit protein bS18m
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein mS23
- Small ribosomal subunit protein uS10m
- Small ribosomal subunit protein mS43
- Small ribosomal subunit protein uS2m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein uS17m
- Small ribosomal subunit protein mS47
- Small ribosomal subunit protein bS21m
Sequence:
MTLAELLGRSRIAQVANNHKPLTYTGKKFHPTHQIIETKPSTLYRQEWGLKSAIPSKIKSRYLVYNDLDTLERITTFEPRGGTQWNRLRFQEMGVPIVSNIGRQNPFFKYISRPEDESHAKLSLFKEMKGDTDISPAAMKKRLKKITALIRSFQDEFKEWLVENHPDELKLNSNKLEDYVVKFLNKKLETKTNKKFNTEIIGTGGLSYSLPGKLKNSPNGVIQRTVVPGRILNVVKENNDNKWLAAIGGFVADVVFFQSPPSSFNSMGDFIRMKTFLFEILEASMEKNGSVSMHARLLEPQNDKTREFFNKRPIYKPLTSRRARRPSVGNIQEANNLLNIIKGN
Protein: Os04g0636700 protein (A0A0P0WFI1)
Organism: Oryza sativa subsp. japonica (Rice)
Interaction partners:
- DNA-directed RNA polymerase
- DNA-directed RNA polymerase subunit beta
- DNA-directed RNA polymerase subunit beta''
- DNA-directed RNA polymerase subunit beta
- DNA-directed RNA polymerase
- DNA-directed RNA polymerase subunit beta'
- Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 homolog
- Os09g0110400 protein
- Decapping nuclease
- Os02g0116900 protein
Sequence:
MNNSAFSEEILAEKLAKLNNTQQCIETLSHWCIYHRKNAEQIVQTWAKQFHSSGNEQKTPFLYLANDILQNSKRNGTEFVEEFWKVLPGALKDVTENGDERGKKVVSRLVEIWQERRVFGSRAGGIKDVMLGTVPLPVLDMTKKRSHGSSIKIVKRDSRSVKLRLGVGGTAEKIVSALHTVLSEQADEDSDLEKCKTSMRRVGKMQKDVSSACSKGDDPRRETLCTELKEEEDSMTECIEKLKVVEANRATVVSELKEALQEQESELEKVRTQLQLAEAMVEEAADMQRKLKNEPVIPSSKHLSSVEPGKPLSNGQAKDQQKTAAAILADKIAASSNSQQILQSALSKFAAEEAKNSSETHQDKRLKIEHSSQVPSVANAAAFVPMPQMTTTTAQQPQAILVQQTPMQNQPPAPQPQYNIYQAPPHQFVQQPGGVMMGMAYNMSTMAPPPPPPPQMMNLARPSPSTPQPPMGIMPQTQPPPPAPTMLQQQMPMNVGPPMQFALQQSGAPSFRPLQPPPGMQFFHPQSQ
Protein: Capsid protein (Core antigen) (Core protein) (HBcAg) (p21.5) (B1Q2W9)
Organism: Hepatitis B virus subtype adr (HBV)
Subcellular location: Secreted {ECO:0000256|RuleBase:RU361253}. Virion {ECO:0000256|HAMAP-Rule:MF_04076}. Host cytoplasm {ECO:0000256|HAMAP-Rule:MF_04076}.
Interaction partners:
Sequence:
MQLFHLCLIISCSCPTVQASKLCLGWLWGMDIDPYKEFGASVELLSFLPSDFFPSIRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMNLATWVGSNLEDPASRELVVSYVNVNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
Protein: C2H2-type domain-containing protein (A0A178UA35)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MSLFCNSIETLYPKPFLSHKSHFFTFSNSKFQNPKFTSFPLRHQWRIESCLKSASSSEIDMVRNKEGIFAPKEKKVVVLWDLDNKPPRGPPYEAATALRKVAEKLGRVVEISAYANRHAFIHLPHWVVEERRERRNLDFMERKGEVTPIDPYICGVCGRKCKTNLDLKKHFKQLHERERQKKVNRMRSLKGKKRQKFKERYVSGNEKYNEAARSLLTPKVGYGLEAELRRAGVYVKTVEDKPQAADWAVKRQIQHSMTRGIDWLVLVSDDKDFSDMLRKAREADLGTLVVSDMDRALGRHADLWVPWSGVEKGEIGEKDLIPGKRPRFEEDEVGFGGNDELFSLSYDEDEKAEMTVESDGFGRFNVSAFSEDEWVEDEGDFVLSDSSDDDSDDELF
Protein: Human/fission yeast MIS (MInichromosome Stability) homolog (Q9N3R7)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MESELSGISNENQISFFGFSAGSFSDSIFNIYVDAWEEVCSNEFKNSLKKLTDKDRLCLLSFPFSDKTNEKAFKMMKRFCVTNIFRIPASVTLPECKKMLIASAKEHKSLKQVEKEFDEKLEKIRQLRIKLAKRHDELEAVNNAIEVLHVMEKSQEQLISQKRIVPDSPTRMSPV
Protein: Metalloendopeptidase (EC 3.4.24.-) (F1REM3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MELAARCALLLSSFSLLAALDLDAIEPGYYVETSSPSDLIDYKDPCKAVAYLGDIALDEEDMRMFTVDRIVNLADRTVTILNHTNTGSLSNETSVNTTASSRGSHRRRRAATSRPERVWPEGVIPYVISGNFSGSQRAIFRQAMRHWEKHTCVTFIERTTEESYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDEHVSIIRDNIQPGQEYNFLKMEPGEVDSLGEVYDFDSIMHYARNTFSRGIFLDTILPRYDVNGVRPPIGQRTRLSKGDIAQARKLYKCPRCGDSLQESSGNFSSPGYPNGYSAYMHCIWRISVTPGEKIILNFTSMDLYRSHLCWYDHVEIRDGYWRKAPLKGRFCGDKLPDPIISTDSRLWIEFRSSSNWVGKGFSAVYEAICGGEVKKDNGQIQSPNYPDDYRPNKVCVWKITVAQGYHVGLTFQSFEIERHDNCAYDYLEVRDGNSESSPLLGRFCGYDKPDDIKSSSNQLWMKFVSDGSVNKAGFAANFFKEMDECSRPDNGRCEQRCVNTLGSYKCACDPGYELAADKRSCEAACGGFITKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRITLLFDVFETEGNDVCKYDFVEVRSGLSADSRLHGKFCGAEKPEAITSQYNNMRIEFKSDNTVSKKGFKAQFFSDKDECSKENGGCQHECVNTFGSYSCQCRSGFVLHENKHDCKEAGCDHVVNSVSGTITSPNWPDKYPSKKACTWALSTTPGHRIKIAFNEIDMEPHLECAYDHIEIYDGRDSKAQSLGRYCGTKKPQPIISTGNKMFIRFFSDNSVQKKGFEASHTAECGGRLKAEVKTKDLYSHAQFGDNNYPGASDCQWVITAEKGYGVELIFQTFEIEEEADCGYDYMELFDGADTKSPRLGRYCGSGPPEEIYSAGDSIVIKFHSDDTINKKGFHVRYTSTKFQDTLHSRKK
Protein: Probable inactive receptor kinase At4g23740 (Q9SUQ3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Protein RETICULATA, chloroplastic
- F-box/kelch-repeat protein At1g51550
- At1g19540
- V-type proton ATPase subunit c3
- Phosphatidylinositol/phosphatidylcholine transfer protein SFH6
- Cysteine-rich repeat secretory protein 18
- Putative clathrin assembly protein At2g01600
- At1g48690
Sequence:
MEALRIYLWSLCLSLCLIIYGANSDPLEDKRALLEFLTIMQPTRSLNWNETSQVCNIWTGVTCNQDGSRIIAVRLPGVGLNGQIPPNTISRLSALRVLSLRSNLISGEFPKDFVELKDLAFLYLQDNNLSGPLPLDFSVWKNLTSVNLSNNGFNGTIPSSLSRLKRIQSLNLANNTLSGDIPDLSVLSSLQHIDLSNNYDLAGPIPDWLRRFPFSSYTGIDIIPPGGNYTLVTPPPPSEQTHQKPSKARFLGLSETVFLLIVIAVSIVVITALAFVLTVCYVRRKLRRGDGVISDNKLQKKGGMSPEKFVSRMEDVNNRLSFFEGCNYSFDLEDLLRASAEVLGKGTFGTTYKAVLEDATSVAVKRLKDVAAGKRDFEQQMEIIGGIKHENVVELKAYYYSKDEKLMVYDYFSRGSVASLLHGNRGENRIPLDWETRMKIAIGAAKGIARIHKENNGKLVHGNIKSSNIFLNSESNGCVSDLGLTAVMSPLAPPISRQAGYRAPEVTDTRKSSQLSDVYSFGVVLLELLTGKSPIHTTAGDEIIHLVRWVHSVVREEWTAEVFDIELLRYTNIEEEMVEMLQIAMSCVVKAADQRPKMSDLVRLIENVGNRRTSIEPEPELKPKSENGASETSTPSEI
Protein: Multidrug resistance-associated protein 1 (G5EFP3)
Organism: Caenorhabditis elegans
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MEPNLQAKLKGIDAFCGERYWDPAVWNASTVPILSQCYQHTTLVWFPTAIVFLLAPILTAQIFYRRPNPIPWTRRIQLKIGLACILIADSLSLFTVAIYETLFQGFPYAVDFVYPLTLCLAMVVLTALIVSCRNYGIVTSGGLFISWLVFTISAIPELLYWIQQIVNPAEAWNWIDYPRCIAFFIWFFCCAFETYLHCYADASPEGYKYLSAARNPSPETTSSFLNRITMWWFNSLCSLGVKKPLEVSDLYSLNEADTSNLLVPKWYNLWDKQSKKFEETAARRRIGSNASRTNRRRTSSNDTTPLLNDQSTDDYGSVPAGQSTQKMPSIIWTLFLMFKWDVITAMFVKLLSDVLLFCNPLLLKSLIRFTEELERPMWQGVVLAFTMFFSAELSSILLSHYFYLMYRVGTRVQTCLTAAVYRKTLRLSNAARREKTVGEIVNLMAIDVDRFQQITPQTMQYWSNPFQIGLALFLLFQQLGVSVFSGVAVMVLLFPINFVITMIIRKWQIAQMYYKDERTKMVNEVLNGIKVIKLYAWEPPMEQVIEDLREQELGLIKKAAFLRTFSDMLNTASPFLVALSTFATFIYIDPKNVLTPEIAFVSLTLFNQLRSPMSQVAELITQTVQVVVSNRRLKEFLVSEELNVEAIDHRARDNNDVICLKEACLSWESAEHQPVPTLTNISFSVNRGQLVTIVGRVGAGKSSMLQALMGEMEKLSGSISMHGRLCYVPQQPWMQNNTLRQNITFGKQFDEYFYSRVLDACALYRDLQILPLGDNTEIGEKGINLSGGQKARISLARAVYQNHDIYLLDDPMSAVDAHVGSQLFGSVIGPEGMLRNKTRILVTNELSFLEKSDLIIVMNEGKIEYSGKYDDLMQQGAFEQLLIECEKEERERREAEASADEDDENSEPGGIMIGGDSDFEYDDDVMASPIIDHVLGTSHMSTVSGIINRRRISTSTHKQRRRLSTTKSHTHSITSASTQTRQLTGTERVETGRVKMDTYYKYFGAMGMSIAVLFVLGMTTSTIFSMGRNLWLTDWSNDNAARSGSNTTGQPIAIRLGVYAGLGFSEIILLFIGMLSLLYGGVSASRNLHAPLMRNLFRVPMAFYDTTPFGRILNRIGKDIETVDVLLPFNVQFFAQCLLQVVSTLIIIMISTPVFGIVIIPLSVMYLMVMRYYIATSRQLKRLESITRSPIYSHLSESIQGSATIRAYHLVDRFCKLSETKVDSHVQCRYLNYVANRWLSVRLEFIGNCIVLFSALFAALTRTTTTSGVIGLSVSYALNITTVLNFAVRQITKLETNIVSVERVKEYAETETEAEWKSEPGKEPPQNWPSEGRIVMNNYSARYRPGLNLVVKQLNVEIKPHEKVGIVGRTGAGKSSVTLSLFRIIEAAEGQIVVDGINLAEIGLHDLRSNLTIIPQDPVLFSGTLRFNLDPFNHYSDGDIWKTLEMANLKEFATAHNEQLNYIITEGGDNISVGQRQLVCLARALLRKTRVLILDEATAAVDVSTDALIQKTIREEFANATVLTIAHRLNTIMDYDRIIVLNDGKVGEFDSPANLLSNRNSEFYSMAKRAGLI
Protein: Negative cofactor 2 complex subunit alpha (NC2 complex subunit alpha) (Transcription repressor BUR6) (P40096)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the NC2 complex which represses RNA polymerase II transcription through binding to SPT15/TBP and thereby inhibiting the assembly of the preinitiation complex. The NC2 complex may also mediate transcriptional activation from TATA-driven promoters through association with SPT15/TBP.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Negative cofactor 2 complex subunit beta
- TATA-box-binding protein
- TATA-binding protein-associated factor MOT1
- Transcription initiation factor IIB
Sequence:
MADQVPVTTQLPPIKPEHEVPLDAGGSPVGNMGTNSNNNNELGDVFDRIKTHFPPAKVKKIMQTDEDIGKVSQATPVIAGRSLEFFIALLVKKSGEMARGQGTKRITAEILKKTILNDEKFDFLREGLCVEEGQTQPEEESA
Protein: Leucine-rich repeat protein (LRRP) (Q38C48)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- SUMO-conjugating enzyme UBC9
- GTP-binding nuclear protein
- Small ubiquitin protein, putative
- Ran-binding protein 1, putative
- RanBD1 domain-containing protein
- Nuclear pore complex protein
- SUMO1/Ulp2, putative
- Nucleoporin
- Poly
- Nuclear pore protein
Sequence:
MRRVFRKSLSGALSYRWCWSPQPGPSYPTPEALVETIRRQGPKESVWNLDFSFLPKRPSTQGEDVPDDVLRSCSVALSESALTVKRLSLTINSPEAVEVAIRFLRGAQLPALRTLDLTLHNVAFVQNERMLATLLQSAAGVAGRLAELRVAMITHDIRSGLQWGRQQRVPTALATLLSASALESLSLEHLVMSSTSDEETLVLNAAILNSCRGLRQLSLSGSASLLRCDSFLHDTLMGMPRLEVLDLSGICLNDVQIQKLLVSLRVSIGGWHNLQQLNLAGCGLSTWALGLMQNDLGDPHPLPSNSSFGLKVLNLSSNGIDDEGAFVLATVCMRCRWIEEIYLRHNRITEKGAAAICSAVREGTELRVLSFHSNLLKDEGLLEVLRHFEGWPKLQRFDVTRCRLTVRCLPSLCIALLSSKALQELVLDRNDLRLLDTSDVTGTTGGGVHLFAFDSMRSGIGSADIKALTSFEVDRRDALEGRQRHKGTGPANEEKKFNSTFIGAAPFERLGSALASCAELRSFSASGCSLTDTAFLSLTAALQRCRLTHLNLSSNPLFTHVEGIEALGRLLHCASEALEVLDVSCTGLGNVGIAVLADGLSDSVSEMVGEPPLRSLGALRELHVSHCRIGDDGFGALADVVPFMCSLERLFLDGNQVTSVPVVVSLLGKLSTLPSLVFVGLHGTLSPRSGAEVAVCSEYSLLRRKGITVHV
Protein: Uncharacterized protein C191.10 (Q9Y7Q3)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- Invertase
Sequence:
MHSSRRKYNDMWTARLLIRSDQKEEKYPSFKKNAGKAINAHLIPKLSPKMNIMRSSCGRQEISQFQTKIRLFFLPHSCGVNDVTDLGGKDDELVGKRKKWKTEVRIETSMAECNGGKDFTEMTRIYLSIRKNFFQICLKTHSPQLPLGR
Protein: Presequence protease, mitochondrial (PreP) (EC 3.4.24.-) (Pitrilysin metalloproteinase) (Q5B6H7)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Degrades mitochondrial transit peptides after their cleavage in the intermembrane space or in the matrix, and presequence peptides; clearance of these peptides is required to keep the presequence processing machinery running (By similarity). Preferentially cleaves the N-terminal side of paired basic amino acid residues (By similarity). Also degrades other unstructured peptides (By similarity). May function as an ATP-dependent peptidase as opposed to a metalloendopeptidase (By similarity).
Subcellular location: Mitochondrion intermembrane space {ECO:0000250|UniProtKB:P32898}. Mitochondrion matrix {ECO:0000250|UniProtKB:P32898}.
Interaction partners:
Sequence:
MLRSYLHLGRHRTPAFRQPLGRLLRPTASILQYAQSRTLASVSSLESLPEVGDQLHGFTVQEKKQVPELHLTAIRLRHDKTHADYLHIAREDKNNVFGIGFKTNPPDATGVPHILEHTTLCGSEKYPIRDPFFKMLPRSLSNFMNAFTSSDHTMYPFATTNQQDFQNLLSVYLDATMHPLLKEEDFRQEGWRLGPEDPRAIQTQEGNLKPEDILFKGVVYNEMKGQMSDANYLYWIRFQESIFPAINNSGGDPQHITDLTHKQLVEFSKKNYNPSNAKIITYGDMPLADHLKQVGGVLNDFSKGAVDTTVKLPIELRGPINVTVPGPIDTFVSEDRQFKTSTSWYMGDITDTVETFSAGILSSLLLDGYGSPMYKALIESGLGSSFTPNTGLDTSGKIPIFSIGVTGVSEEQAPRVKEEIQRVLQETLQRGFNDEKVQGFLHQLELALRHKTANFGLGVIQKTFTSWFNGSDPMKELAWNEVINAFKSRYEKGGYLEALMQKYLINDNCLTFTMVGTPSFNKELDDKEMARKEKKFEQLTQQHGSVEKAVTELAKAELQLLEVQEKAQHADLSCLPSLRVEDISRQKEHKPVRESKVEGTDIVWREAPTNGLTYFQAVNAFADLPDDLRLLLPLFNDAIMRLGTPTRTMEQWEDLIKLKTGGVSTSNFHTTSPTEMGKYTEGLQFSGFALDKNVPDMLEILTALVTETDFTSPSAPAMIQELLRLTTNGALDAVAGTGHRYALNAAAAGLSRSFWAQEQTSGLAQLQATANLLRDAETSPERLAELIEKLRLIQSFAISKTSGLRVRLVCEPASSTQNESVLQRWVTGLPKVPSPTSQPQRFDLSTPSKKAFYDLPYKVYYSGLALPTVPFTHSSSATLSVLSQLLTHNYLHPEIREKGGAYGAGASNGPVKGLFAFTSYRDPNPANTLKVFKNSGVFARDRAWSDREINEAKLGIFQGLDAPVSVDEEGSRYFLNGITHEMDQRWREQVLDVTAKDVNEVAQTFLVDGTRRSVCLLGEKKDWAESEGWEVRKLSMNPNGSNIPSGDAA
Protein: Probable ATP-dependent RNA helicase DDX56 (EC 3.6.4.13) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD box protein 21) (DEAD box protein 56) (Q9NY93)
Organism: Homo sapiens (Human)
Function: Nucleolar RNA helicase that plays a role in various biological processes including innate immunity, ribosome biogenesis or nucleolus organization. Plays an essential role in maintaining nucleolar integrity in planarian stem cells. Maintains embryonic stem cells proliferation by conventional regulation of ribosome assembly and interaction with OCT4 and POU5F1 complex (By similarity). Regulates antiviral innate immunity by inhibiting the virus-triggered signaling nuclear translocation of IRF3. Mechanistically, acts by disrupting the interaction between IRF3 and importin IPO5. May play a role in later stages of the processing of the pre-ribosomal particles leading to mature 60S ribosomal subunits. Has intrinsic ATPase activity.
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:22925334, ECO:0000269|PubMed:31340999, ECO:0000269|PubMed:33789112}.
Interaction partners:
- ATP-dependent DNA/RNA helicase DHX36
- ATP-dependent RNA helicase DDX1
- Ribosome production factor 2 homolog
- CCAAT/enhancer-binding protein zeta
- GTP-binding protein 4
- WD repeat-containing protein 74
- Probable rRNA-processing protein EBP2
- Nucleolar complex protein 2 homolog
- Pescadillo homolog
- WD repeat-containing protein 46
Sequence:
MEDSEALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQLLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVSQRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELKSLLCHLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFLLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFNQGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPPTPEAYIHRAGRTARANNPGIVLTFVLPTEQFHLGKIEELLSGENRGPILLPYQFRMEEIEGFRYRCRDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFEDNPRDLQLLRHDLPLHPAVVKPHLGHVPDYLVPPALRGLVRPHKKRKKLSSSCRKAKRAKSQNPLRSFKHKGKKFRPTAKPS
Protein: Ribosomal RNA processing protein 45 (EC 3.1.13.-) (Q583T6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Exosome component CSL4
- Ribosomal RNA-processing protein 43
- Ribosomal RNA processing protein 4
- Exosome complex exonuclease RRP40
- RNasePH-like protein exosome-associated protein 1 Rrp42 homologue
- ATP-dependent DEAD/H RNA helicase, putative
- PNO1 second type I KH domain-containing protein
- Elongation factor 1-alpha, putative
- Ribosomal RNA processing protein 6
- Exosome-associated protein 4
Sequence:
MQYQRAALVIASPALTQREVEFTKSAWLAGLRPDQRTAQQMREVSVEFPLLSRDVVVVRCGGSVVTAAIATALVEPTPQRPKHGLLHFSVRRLHTERDSPAADGSTQKNLVAFLERLVRTGGVIDTAGLCVLPGQKVWSLTVDVTIMNDEGNCNDAAVWAVIALLMHHRRPELTVRGSSVIVHPPHEREPVPLSVQHTPLPFTFAITMAPTEREKALNHQRALSATGSSSGPQPSSGVGNSIDTASAFAIDGTSPQPLGVVVDPTTAESLAAASSIVVAINAEGQVCTVVKAEGCSIHLKDLNACIEAAGTLAPRVLDLIKVAMEAHDERRKTAMKGQFAWAQKRSGVGKVEQACVKKIKTET
Protein: beta-carotene 3-hydroxylase (EC 1.14.15.24) (Q10SE7)
Organism: Oryza sativa subsp. japonica (Rice)
Subcellular location: Plastid, chloroplast membrane {ECO:0000256|ARBA:ARBA00004508}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004508}.
Interaction partners:
- Cytochrome P450 family protein, expressed
- Os02g0817900 protein
- beta-carotene 3-hydroxylase
- beta-carotene 3-hydroxylase
- Os04g0448950 protein
- Zeaxanthin epoxidase, chloroplastic
- lycopene beta-cyclase
- Os04g0379700 protein
- Beta-carotene isomerase D27, chloroplastic
Sequence:
MAVARLVAARAPLLSPAAVAAAHRSPPALLRLAFAPLPARRLAVPLRVAVGEPEPEEDARRAVAERAARKQSERRTYLVAAVMSSLGITSMAAAAVYYRFAWQMEGSGEIPVTEMFGTFALSVGAAVGMEFWARWAHRALWHASLWHMHESHHRPRDGPFELNDVFAITNAVPAMSLLAYGFFTRGLVPGLCFGAGLGITLFGMAYMFVHDGLVHRRFPVGPIANVPYFRRVAAAHQIHHMDKFEGVPYGLFLGPKELEEVGGIEELEKEIKRRIKRKETLDAIQ
Protein: Immune-associated nucleotide-binding protein 6 (AtIAN6) (AIG1-like protein) (Q9C8V0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MAEDQNTTDRWELPSASEPVKNVDRWELPSASEPVKNVVLVGRTGNGKSATGNSIIGRKVFESKYQAVGVTTRCKTFRAVTPDGPIINVIDTPGLFDLAVSAEFISKEIVNCLILAREGLHAVVLVLSLSTRISQEEENALCTLQMLFGGKIVDYLIVVFTCGDMLEDRNMTLEDYLSNGCPEFLKNVLRLCGGRRVVFDNRTKDEGVKAKQVQQLLVHVAAIEKETGGNPFTDTMHRRIQEEAARVKREEKEIEEKNIADEEKAALKKQLDMSYSQNMNMMALMMERIFKETAAANERQMNMMKDFMEISIIGNDAHRKRAEEKQAEKKQECNIL
Protein: Serine/threonine-protein kinase KIC1 (EC 2.7.11.1) (Kinase that interacts with CDC31) (N-rich kinase 1) (P38692)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Protein kinase involved in morphogenesis and cell integrity.
Interaction partners:
- Protein HYM1
- Leucine-rich repeat-containing protein SOG2
- CBK1 kinase activator protein MOB2
- Cell morphogenesis protein PAG1
- Serine/threonine-protein kinase CBK1
- Metallothionein expression activator
- Factor arrest protein 8
- Cell division control protein 31
- T-complex protein 1 subunit theta
- Factor arrest protein 11
Sequence:
MTTKPQNSKQGLAEGEMDVSSLFKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSDSDEVEDVQREIQFLASLKQISNITRYYGSYLKDTSLWIIMEHCAGGSLRSLLRPGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVNQTSLRRQTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYCDVEALRAMQLIIKSKPPRLEDRSYSTSLKEFIALCLDEDPKERLSADDLLKSKFIRAHKATPTSILKELISRYLLFRDKNKNKYKIEGSIPENEPSKPSEAPKPSQNGGGDEAQKSIASNDNEIKRVNEGDVEMKWDFDSLSSSDYIIENNINLDALAEDNNEWATAQHDLFNYAYPDEDSYYFDPTSHNTRPFVYQGTTIGKGYPGTIAQNSTLNAPVTNNYTNSKYPSKMVAGTTNTSGTHTAGPMTSSKRLESKAPKQLLELFEDNEIITAENDVNTEAPKISKSISSLNAGNSSRDDFIPSISNEVNGNINNNKMRPHLPPLSSGNNYYSQSTPALPLLQTKFNKTSKGPPTSGLTTAPTSIEIEIPEELPNSALPTPASADPVLIPSTKARSSTVTAGTPSSSSSIQYKSPSNVPRRLTVSNNRPEHCPSTITNQKLGSAVASNSGISSTPNNSNNYNNNTDSENSRGSSGSNTANSTQMGITNPGNVTKLSTHKASSPSRPLFGVGTSPNRKPAGSPTQNIGHNSTHTNLAPPPTMKPMANSKDNKDILLQPLNSIPSSSTLNTISGNSSNNLTSSNYFSNEKEGSRVNGDFKRNNPNLKLQMPLPTPVVRNKLLDPNTATSQNNNGMPGSAGISTNENINQFGFNTSSASNIPVSMTPISEKHIDFGGKIKRSQSISNRKNSSASEHPLNILGSSVSGNVSGIGNNNVGSNNNSGPNNSVPLSANTGNTTIKANSTTIATSSSAAASTTAPISQQTIPSGTQFNHILSSAATAANSVNSLGFGMCPPPQSLQMEMFLDLESFLPGKQRRVDRKPQVLKELENLLQMFEEGLPCIEHALKEQLISTPIKDNEH
Protein: Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2) (Q8CCK0)
Organism: Mus musculus (Mouse)
Function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.
Subcellular location: Nucleus {ECO:0000269|PubMed:11262398}. Chromosome {ECO:0000269|PubMed:11262398}. Note=Enriched in inactive X chromosome chromatin and in senescence-associated heterochromatin.
Interaction partners:
- Ganglioside-induced differentiation-associated protein 2
- Histone deacetylase 4
- Histone H3.2
- Lysine-specific demethylase 6A
- Histone H2B type 1-A
- Histone H3.3
- Histone H4
- Histone H3.1
- Histone deacetylase 1
- Histone deacetylase 11
Sequence:
MSGRSGKKKMSKLSRSARAGVIFPVGRLMRYLKKGTFKYRISVGAPVYMAAVIEYLAAEILELAGNAARDNKKARIAPRHILLAVANDEELNQLLKGVTIASGGVLPRIHPELLAKKRGTKGKSETILSPPPEKRGRKAASGKKGGKKSKATKPRTSKKSKAKDSDKEGTSNSTSEDGPGDGFTILSSKSLVLGQKLSLTQSDISHIGSMRVEGIVHPTTAEIDLKEEIGKALEKAGGKEFLETVKELRKSQGPLEVAEAAVSQSSGLAAKFVIHCHIPQWGSDKCEEQLEETIKNCLSAAEDKKLKSVAFPPFPSGRNCFPKQTAAQVTLKAISAHFDDSSSSSLKNVYFLLFDSESIGIYVQEMAKLDTK
Protein: Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (A5PJQ9)
Organism: Bos taurus (Bovine)
Interaction partners:
Sequence:
MGEAEKFHYVYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVTCQVFAEGKPLALPVRTSYKAFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGKAVPVGGTTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTKTPGRTSSTLSEDQMSRLAKLTKAHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFRCVKCDDKEYGIVYYEKDGDESSPILTSFEIVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDLKPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGRWKPMDVEDSLELLSPHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYENFDDIKNGLEPTKKDSQGSVSESVSNSGINSAEIDSSQIITSPLPPVSSPPSASKTKESSDGENLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRK
Protein: Large ribosomal subunit protein uL30 (60S ribosomal protein L7) (P32100)
Organism: Drosophila melanogaster (Fruit fly)
Function: Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (By similarity).
Interaction partners:
- GEO07453p1
- Large ribosomal subunit protein uL18
- Large ribosomal subunit protein eL33
- Small ribosomal subunit protein eS17
- Small ribosomal subunit protein uS13
- Small ribosomal subunit protein uS4
- Small ribosomal subunit protein uS7A
- Large ribosomal subunit protein uL14
- Small ribosomal subunit protein uS10
- Large ribosomal subunit protein uL4
Sequence:
MPAPVVKKPAAKKLPAVPESKLKFSKKQISKRVAESKRRLKKAAVIALRKKENLVRAEKYQNEYIKAEQREIKLRRLAKKRNQFYVPAEAKLAFVVRIRGINKVAPKVRKVLQLFRLRQINNGVFIKLNKATINMLRIAEPYITWGYPNLKSVRELIYKRGFVKHNRQRVPITDNFVIERKLRQAHQIQCVEDLVHEIFTVGPNFKYASNFLWPFKLNTPTGGWRKKANHYVNGGDFGNREDQINRLLRKMV
Protein: fMet-Leu-Phe receptor (fMLP receptor) (N-formyl peptide receptor) (FPR) (N-formylpeptide chemoattractant receptor) (P21462)
Organism: Homo sapiens (Human)
Function: High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release. Receptor for cathepsin CTSG, leading to increased phagocyte chemotaxis.
Subcellular location: Cell membrane {ECO:0000269|PubMed:15153520, ECO:0000269|PubMed:2176894, ECO:0000269|PubMed:25109685, ECO:0000305|PubMed:10514456}; Multi-pass membrane protein {ECO:0000255}. Note=Internalizes in presence of its ligands, fMLP, TAFA4 and CTSG. {ECO:0000269|PubMed:15210802, ECO:0000269|PubMed:25109685}.
Interaction partners:
- Annexin A1
- N-formyl peptide receptor 2
- N-formyl peptide receptor 3
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Triggering receptor expressed on myeloid cells 1
- C-X-C chemokine receptor type 1
- Guanine nucleotide-binding protein G
- C-X-C chemokine receptor type 2
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK