wanglab/gogpt-training-data huggingface dataset:
Protein: Protein phosphatase 1, regulatory subunit 9A (H3BL28)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Synapse {ECO:0000256|ARBA:ARBA00034103}.
Interaction partners:
Sequence:
MLKAESSGERTTLRSASPHRNAYRTEFQALKSTFDKPKSDGEQKTKEGEGSQQSRGRKYGSNVNRIKNLFMQMGMEPSENAAIIAKTRGKGRPSSPQRRMKPKEFVEKTDGSVVKLESSVSERISRFDTMHDGPSYAKFTETRKMFERSVHESGQNHRYSPKKEKGGGTEPQDEWGGSKSNRGSSDSLDSLSPRTEAVSPTVSQLSAVFENSEPPGALTSGKAESADYSVTGHYPLNLPSVTVTNLDTFGRLKDSNSKPPSNKQDTDTEDAQKSDAVPVPEVAQKGTSLASLPSEESQLSTEAEDVTTAQPEALDSTDKDSPEEPSAENQAMPKSHILSPRNEPLEDAEANVVGSERAQHQKKDLTGGDLTSPDASASSCGREVPEDSNSFESSHVYMHSDYNVYRVRSRYNSDWGETGTEQDEEEDSDENNYYQPDMEYSEIVGLPEEEEIPANRKIKFSCAPIKVFNTYSNEDYDRRNDDVDPVAASAEYELEKRVEKLELFPVELEKDEDGLGISIIGMGVGADAGLEKLGIFVKTVTDGGAAQRDGRIQVNDQIVEVDGISLVGVTQNFAATVLRNTKGNVRFVIGREKPGQVSEVAQLISQTLEQERRQRELLERHYAQYDADDDETGEYATDEEEDEGGPILPSGDVAIEVFELPENEDMFSPSDLDTSKLSHKFKELQIKHAVTEAEIQKLKTKLQAAENEKVRWELEKNQLQQNIEENKERMLKLESYWIEAQTLCHTVNEHLKETQSQYQALEKKYNKAKKLIKDFQQKELDFIKRQEVERKKREEVEKAHLLEVQGLQVRIRDLEAEVFRLLKQNGTQVNNNNNIFERRPSPGEVSKGDTMENVEVKQTSCQDGLSQDLNEAVPETERLDSKALKTRAQLSVKNRRQRPTRTRLYDSVSSTDGEDSLERKNFTFNDDFSPSSTSSADLSGLGAEPKTPGLSQSLALSSDESLDMIDDEILDDGQSPKHTQSQNRAVHEWSVQQVSHWLMSLSLDQYVPEFSAQSISGEQLLQLDGNKLKALGMTSSQDRALV
Protein: Small ribosomal subunit protein bS16m (28S ribosomal protein S16, mitochondrial) (MRP-S16) (S16mt) (Q9CPX7)
Organism: Mus musculus (Mouse)
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q9Y3D3}.
Interaction partners:
- Large ribosomal subunit protein bL27m
- Small ribosomal subunit protein uS14m
- Large ribosomal subunit protein bL17m
- Large ribosomal subunit protein bL21m
- Large ribosomal subunit protein bL36m
- Small ribosomal subunit protein uS7m
- Large ribosomal subunit protein uL14
- Small ribosomal subunit protein uS9m
- Large ribosomal subunit protein uL5
- Small ribosomal subunit protein mS29
Sequence:
MVQLTTIFCKAYHGGHLTIRLALGGCTNRPFYRIVAAHNKCPRDGRFVEQLGSYDPLPNSHGEKLVALNLDRIRHWIGCGAHLSKPMEKLLGLSGFFPLHPMMITNAERLRRRRAREVLLASQKAESEAKETEAS
Protein: Bifunctional monothiol glutaredoxin-S16, chloroplastic (AtGrxS16) (Atypical GIY-YIG endonuclease) (EC 3.1.-.-) (CAX-interacting protein 2) (CAXIP1-like protein) (Q8H7F6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May only reduce GSH-thiol disulfides, but not protein disulfides (Probable). Participates probably to the maturation of iron-sulfur proteins and to the regulation of the redox state of the BOLA proteins (Probable). The GRXS16-BOLA1 heterodimer binds a labile, oxygen sensitive iron-sulfur cluster. Able to cleave linearized DNA in vitro.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:23690600}.
Interaction partners:
- SufE-like protein 1, chloroplastic/mitochondrial
- Protein BOLA4, chloroplastic/mitochondrial
- Protein BOLA1
- NifU-like protein 4, mitochondrial
- NifU-like protein 2, chloroplastic
- NifU-like protein 5, mitochondrial
- Glutaredoxin-C1
- Fe-S cluster assembly factor HCF101, chloroplastic
- Protein BOLA2
- Iron-sulfur assembly protein IscA, chloroplastic
Sequence:
MAAITISSSLHASASPRVVRPHVSRNTPVITLYSRFTPSFSFPSLSFTLRDTAPSRRRSFFIASAVKSLTETELLPITEADSIPSASGVYAVYDKSDELQFVGISRNIAASVSAHLKSVPELCGSVKVGIVEEPDKAVLTQAWKLWIEEHIKVTGKVPPGNKSGNNTFVKQTPRKKSDIRLTPGRHVELTVPLEELIDRLVKESKVVAFIKGSRSAPQCGFSQRVVGILESQGVDYETVDVLDDEYNHGLRETLKNYSNWPTFPQIFVKGELVGGCDILTSMYENGELANILN
Protein: endothelin-converting enzyme 1 (EC 3.4.24.71) (A0A8I5ZM37)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000256|ARBA:ARBA00004250}. Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004194}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004194}. Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
Interaction partners:
Sequence:
MVEYKRAKLQDEELPEVTVEGRAIQDSLEVGSQKRTRQLFGSHTQLELVLAGLILVLAALLLGCLVALWVQYHRDPVHSTCITEACIRVAGKILESLDRGVSPCQDFYQFSCGGWIRRNPLPSGRSRWNTFNSLWDQNQAILKHLLENSTFNSSSEAERKTRSFYLSCLHLERIEKLGAKPLQDLIDKIGGWNITGPWDEDNFMEVLKAVAGTYRAAPFFTVYVGADSKSSNSNIIQVDQSGLFLPSRDYYLNRTANEKVLAAYLDYMVELGMLLGGQPTSTRAQMQQVLELEIQLATITVPQDQRRDEEKIYHKMSISELQTLAPSMDWLEFLSFLLSPLELGDSEPVVVYGTEYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDQRFETAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRAAFEETLENLVWMDEKTRLAAKEKADAIYDMIGFPDFILEPRELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYAHNHPKALNFGGIGVVMGHELTHAFDDQGREYDQEGNLRPWWQNESLTAFQNHTACMEEQYNQYQVNGERLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEEQPLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
Protein: Histone H3-like centromeric protein CSE4 (Q8IDZ1)
Organism: Plasmodium falciparum (isolate 3D7)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Zinc finger protein, putative
- Histone H4
- Heterochromatin protein 1
- Histone H2A
- Histone H2B
- Histone H2B
- Histone chaperone ASF1, putative
- Histone H2A
- NAD-dependent protein deacylase Sir2A
- JmjC domain-containing protein, putative
Sequence:
MVRTKKNIPNHNPLNAFNRDKSFKTNKTLPNRTVHHGISSKTTNINRPSVNRGGINEVAQKNLHRTNIRKPHRYRPGVLALKEIRAYQASTQLLIPKIPFVRVVKEITRLFELPDEQFRYTPEALLALQTASEAYLVSLFEDAYLCSLHANRVTLMPKDIHLARRIRGRD
Protein: Protein V (P0C765)
Organism: Newcastle disease virus (strain Chicken/United States/B1/48) (NDV)
Function: Protects the virus against cell antiviral state by blocking host interferon signaling. Mechanistically, targets host phosphorylated STAT1 (phospho-STAT1) for degradation, thereby inhibiting the interferon alpha signaling pathway. Plays a role in the inhibition of host apoptosis. Interacts with and down-regulates the expression of host TXNL1. In turn, inhibits TXNL1-induced apoptosis through the BCL2-BAX-caspase 3 pathway. Inhibits host apoptosis also by negatively regulating host CacyBP/SIP. Promotes viral replication by activating the extracellular signal-regulated kinase (ERK) pathway.
Subcellular location: Host cytoplasm {ECO:0000269|PubMed:30213106, ECO:0000269|PubMed:30234028, ECO:0000269|PubMed:30290847}. Host nucleus {ECO:0000269|PubMed:30213106, ECO:0000269|PubMed:30234028, ECO:0000269|PubMed:30290847}.
Interaction partners:
Sequence:
MATFTDAEIDELFETSGTVIDNIITAQGKPAETVGRSAIPQGKTKVLSAAWEKHGSIQPPASQDNPDRQDRSDKQPSTPEQTTPHDSPPATSADQPPTQATDEAVDTQLRTGASNSLLLMLDKLSNKSSNAKKGPMVEPPRGESPTSDSTAGESTQSRKQSGKTAEPSQGRPWKPGHRREHSISWTMGGVTTISWCNPSWSPIKAEPKQYPCFCGSFPPTCRLCASDDVYYGGDFPKSK
Protein: Glutamate-pyruvate aminotransferase AlaC (EC 2.6.1.2) (P77434)
Organism: Escherichia coli (strain K12)
Function: Involved in the biosynthesis of alanine. Catalyzes the transamination of pyruvate by glutamate, leading to the formation of L-alanine and 2-oxoglutarate. Is also able to catalyze the reverse reaction.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Valine--pyruvate aminotransferase
Sequence:
MADTRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMGNPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLRRAISRWYQDRYDVEIDPESEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNELERAIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVYDGWKAPSIMQVPGARDVAVEFFTLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWMVEMPKASMYVWAKIPEPYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAIRGIKAMFRADGLLPASSKHIHENAE
Protein: Small ribosomal subunit protein uS8A (40S ribosomal protein S15Aa) (P48149)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein eS1
- Small ribosomal subunit protein eS12
- Ribosomal protein S30, isoform A
- 40S ribosomal protein S15
- Small ribosomal subunit protein eS19A
- Small ribosomal subunit protein uS2
- Small ribosomal subunit protein eS28
- Ubiquitin-ribosomal protein eS31 fusion protein
Sequence:
MVRMNVLADALKCINNAEKRGKRQVLLRPCSKVIIKFLTVMMKHGYIGEFEIVDDHRSGKIVVNLTGRLNKCGVISPRFDVPINDIEKWTNNLLPSRQFGYVVLTTSGGIMDHEEARRKHLGGKILGFFF
Protein: Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC 3.1.3.16) (EC 3.1.3.53) (P62207)
Organism: Gallus gallus (Chicken)
Function: Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity.
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Interaction partners:
- Protein phosphatase 1 regulatory subunit 12A
- Serine/threonine-protein phosphatase
- Eukaryotic translation initiation factor 2 subunit 1
- Protein phosphatase 1 regulatory subunit.
- Retinoblastoma-associated protein
- WD repeat-containing protein 82
- Glycogen [starch] synthase
- Glycogen [starch] synthase
- Protein phosphatase 1 regulatory subunit 3C
- Protein phosphatase 1 regulatory subunit 3C
Sequence:
MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPVTPPRTANPPKKR
Protein: Dihydropyrimidinase-related protein 3 (DRP-3) (Unc-33-like phosphoprotein 1) (ULIP-1) (Q62188)
Organism: Mus musculus (Mouse)
Function: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Cell projection, growth cone {ECO:0000250}. Note=Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone. {ECO:0000250}.
Interaction partners:
- Dihydropyrimidinase-related protein 2
- Dihydropyrimidinase-related protein 1
- Dihydropyrimidinase-related protein 5
- Semaphorin-3A
- Actin-related protein 2/3 complex subunit 3
- Mitogen-activated protein kinase kinase kinase 1
- Actin-related protein 2/3 complex subunit 2
- PDZ and LIM domain protein 4
- Actin, cytoplasmic 2
- KICSTOR complex protein kaptin
Sequence:
MSYQGKKNIPRITSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEANGKMVIPGGIDVHTHFQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPEPESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQSLSKEKGVNSFMVYMAYKDLYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQARMLEMGITGPEGHVLSRPEELEAEAVFRAITVASQTNCPLYVTKVMSKSAADLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEERMSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRIAVGSDSDLVIWDPDALKIVSAKNHQSVAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHVTQGAGRFIPCSPFSDYVYKRIKARRKMADLHAVPRGMYDGPVFDLTTTPKGGTPAGSTRGSPTRPNPPVRNLHQSGFSLSGTQVDEGVRSASKRIVAPPGGRSNITSLS
Protein: Helmsman (Q06RG9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MARWWPILSVVCLCLAVAHGQDKLEGVDVEEVCADRPADEYFRLETDGDCREVYRCTKSGLKEIQCPSGLAFDVIKQTCDWKAKVTNCDEKEKPRKAKPILKTDEPICPEGKLSCGDGECLDKELFCNGKSDCKDESDENACVDEDPNRAPECDPTQCALLSDCFCSADGTRIPGGIEPQQVPQMITITFNGAVNVDNIDLYEDIFNGQRQNPNGCSIKGTFFVSHKYTNYSAVQDLHRRGHEISVFSLTHKDDPNYWTGGSYDDWLAEMAGSRLIVERFANITDGSIIGMRAPYLRVGGNKQFEMMADQFFVYDASITASLGRVPIWPYTLYFRMPHKCNGNAHNCPSRSHPVWEMVMNELDRRDDPTFDESLPGCHMVDSCSNVASGDQFARLLRHNFNRHYNSNRAPLGLHFHASWLKSKKEYRDELIKFIEEMLGRNDVFFVTNLQVIQWMQNPTELNSLRDFQEWKEKCDVKGQPYCSLPNACPLTTRELPGETLRLFTCMECPNNYPWILDPTGDGFSV
Protein: Cytochrome c (P99999)
Organism: Homo sapiens (Human)
Function: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
Subcellular location: Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Interaction partners:
- Cytochrome c1, heme protein, mitochondrial
- Cytochrome b-c1 complex subunit Rieske, mitochondrial
- Apoptotic protease-activating factor 1
- Caspase-9
- Bcl-2-like protein 1
- Cytochrome b
- Apoptosis regulator Bcl-2
- Caspase-3
- Cytochrome b5
- Cytochrome c oxidase subunit 1
Sequence:
MGDVEKGKKIFIMKCSQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGYSYTAANKNKGIIWGEDTLMEYLENPKKYIPGTKMIFVGIKKKEERADLIAYLKKATNE
Protein: Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7) (Q8R537)
Organism: Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Function: Receptor required for the peroxisomal import of proteins containing a C-terminal PTS2-type peroxisomal targeting signal. Specifically binds to cargo proteins containing a PTS2 peroxisomal targeting signal in the cytosol. Cargo protein-binding triggers interaction with PEX5 and formation of a ternary complex composed of PEX5 and PEX7 along with PTS2-containing cargo proteins, which is tranlocated into peroxisomes by passing through the PEX13-PEX14 docking complex.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:10767286, ECO:0000269|PubMed:11756410, ECO:0000269|PubMed:17040904}. Peroxisome matrix {ECO:0000269|PubMed:10767286, ECO:0000269|PubMed:11756410}. Note=Translocated into the peroxisome matrix together with PTS2-containing cargo proteins and PEX5. {ECO:0000250|UniProtKB:O00628}.
Interaction partners:
Sequence:
MSAARTLRVPGRHGYAAEFSPYLPGRLACAAAQHYGIAGCGTLIILDQNQSGLQIFRSFDWSDGLFDVTWSEDNEHVLVTCSGDGSLQLWDTAKATGPLQVYKEHTQEVYSVDWSQTRGEQLVVSGSWDQTVKVWDPTVGNSLCTFRGHESVIYSTIWSPHIPGCFASASGDQTLRIWDVKTAGVRIVIPAHQTEILSCDWCKYNENLVVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKPDPLLETVEHHTEFTCGLDLSLQSPTEVADCSWDETIKIYDPVCLTVPG
Protein: Anaphase-promoting complex subunit 8 (20S cyclosome/APC complex protein apc8) (Cell untimely torn protein 23) (O94556)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the anaphase-promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome. Has a role in promoting metaphase to anaphase transition via the ubiquitination of specific mitotic substrates.
Interaction partners:
- Anaphase-promoting complex subunit 5
- Anaphase-promoting complex subunit 3
- Anaphase-promoting complex subunit cut9
- Anaphase-promoting complex subunit 4
- Anaphase-promoting complex subunit 1
- Anaphase-promoting complex subunit 2
- Mitotic spindle checkpoint component mad3
- Anaphase-promoting complex subunit 11
- Anaphase-promoting complex subunit 10
- Anaphase-promoting complex subunit 14
Sequence:
MTVSLNTMMGVDGLEDQEQLREIRNCLLKCISECSERGLVYAVRWAAEMLNGMNPIEMEHIPFSSTPTGEFDLDPDMANEKLLEVEEKNIYLLAKSYFDCKEFERAAYTLQNCKSSKSIFLRLYSKYLAGEKKSEEENETLLNTNLTLSSTNREFYYISEVLESLHYQGNKDPYLLYLSGVVYRKRKQDSKAIDFLKSCVLKAPFFWSAWLELSLSIDSLETLTTVVSQLPSTHIMTKIFYVYASHELHQVNSSAYEKLAEAEIIFPNSRYLKTQRALLTYDSRDFDEAESLFENILTNDPYRLDDMDTYSNVLFVLENKSKLGFLAQVASSIDKFRPETCSIIGNYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHFYALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRALLGSQTNSSILVRLGNLYEELQDLNSAASMYKQCIKTEETEISPETIKARIWLARWELGKKNYREAELYLSEVLNGDLELEEAKALLRELRSRMEHSYD
Protein: Uncharacterized protein (Q38A94)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MASLSPLESRRNMQLSPYASPRRNPMATLHTREAPLEGREAEAALISATLANAQLRASQAAVEQRSEEVDDLREARDALEREMAEKDEESQAAATYFEKQMTLVKEVNRKLKEELVNERATAELRMEEVVGKMQEELQERDSLIATLKQRLEDVESDLRSVIEFRDARDAHEKEIKELRVVYAEECENHQRNEREMRLQCMEERVRLREKEEKYEREREEEVARLARSYLSKKTRAIEEQNKSLETHISFLSSDADAARNEAETLQKTNNGLRRDAELASSVETMHAVHHAKQRNEIALLRDQVRTTEDNLNSSLEEYEKRLQKQEKIHAAEMMKLSSERDKWRSTAENLRADLLKMRSISEKLIEQRSDMETFFHQALEQVRQEVSEERRNAPHKICFRKPPKGIPSDLLQLTRGREPLMIGDRSHVMPTSHSTLTKKVVDANVSCTNSSVVSRSADTGGGSLPLITMSGSPFFSPANVLVPPIEWRSTSREMQATNGGRLVEERPLGISDLLSVPTAPKIKDLHTVDISQLSWSDKERVLQLLFKHMKRGATAKKTEKRVPTHDTNFLSITPSATPEVNTFLTD
Protein: ISWI one complex protein 3 (P43596)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Functions as component of the ISW1A complex, which acts in remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. The ISW1A complex represses gene expression at initiation through specific positioning of a promoter proximal dinucleosome.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- ISWI chromatin-remodeling complex ATPase ISW1
- ISWI one complex protein 2
- ISWI one complex protein 4
- Imitation switch two complex protein 1
- Protein DLS1
- DNA polymerase epsilon subunit D
- ISWI chromatin-remodeling complex ATPase ISW2
- Chromo domain-containing protein 1
- Non-histone chromosomal protein 6B
- Chromatin structure-remodeling complex protein RSC8
Sequence:
MDSPSNSIQNLQQEAQGSSSAQLADHDHDRVSMAMPLQTDQSVSVSQSSDNLRRSRRVPKPRTSIYDEYEEELKERANKPKRKRPAPPKKKAPSTQNSKSNDKVEKKKTTSIAKDGKPTLKTNDKKVAPKPKPAHEQVEPALIPSNWTSVIPLLTSDFKNQYSVISRLKNPNMKPVPYAGDIIKLMAFINKFSSFFHSDLQNLSFQDFEVGLDLYPGDPNGSAAGIVKGPEDTSLLLYPDFMAIKDIVYCQDKMNLLFLSLLDLTFTENFDGKSAKKKGPLTTWENLKSSSKKVFSNPLYRLRLVAREWGYPREWRQQLPSDQDISKPKTALFEQDEQTPVVDPSHPEILTPNIYTWNANEPLPLESNPLYNREMDKNGILALKPMDRVVLLRALTDWCASHSSAIHDEIYKLTHGKKDPVFGIQTQQVPRYTIEGVDNTINQFKKLCSLIQSRYEIRSKKKHFVKQLKEGKKPDLSRKLEILKEIKAELKNAVKSEKDELLFSLYDKWVPLFEGELPDQPLANPFSERLYKLRLQEFFLGRVPHIGDFYMPRLHSYGDSLEMSTFTDLRNLQALLSKFKNNEYNAFTLFENDGQSMSAQFKLFYHDTPSLAHDVARGRNTSGKVYWYELCHDSATLLEFLEFLDYKIVKPQDEKKEGNEKEKEALNNEAHILEQKSTTDNNPSINTNPLPKDAKYNTARKKLQILKEFLSDYYFILRQFEQMKVQFADMKPGKRQLRRIQRQTVNYNTEYDSEEYVDDEEDDEADIYDDNDNDSSFDDGRVKRQRT
Protein: Clarin-3 (Transmembrane protein 12) (Usher syndrome type-3A-like protein 1) (Q8NCR9)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Transmembrane and immunoglobulin domain-containing protein 1
- Voltage-dependent calcium channel gamma-2 subunit
Sequence:
MPTTKKTLMFLSSFFTSLGSFIVICSILGTQAWITSTIAVRDSASNGSIFITYGLFRGESSEELSHGLAEPKKKFAVLEILNNSSQKTLHSVTILFLVLSLITSLLSSGFTFYNSISNPYQTFLGPTGVYTWNGLGASFVFVTMILFVANTQSNQLSEELFQMLYPATTSKGTTHSYGYSFWLILLVILLNIVTVTIIIFYQKARYQRKQEQRKPMEYAPRDGILF
Protein: Heat stress transcription factor B-4b (Heat stress transcription factor 12) (OsHSF12) (rHsf12) (Heat stress transcription factor 19) (OsHsf-19) (Q7XHZ0)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcriptional activator that specifically binds DNA of heat shock promoter elements (HSE).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Os06g0274000 protein.
Sequence:
MAFLVERCGEMVVSMEMGPHGGGGAAAGKPVPAPFLTKTYQLVDDPCTDHIVSWGEDDTTFVVWRPPEFARDLLPNYFKHNNFSSFVRQLNTYGFRKIVADRWEFANEFFRKGAKHLLAEIHRRKSSQPPPPPMPHQPYHHHHHLNPFSLPPPPPAYHHHHLIQEEPATTAHCTVAGDGGEGGDFLAALSEDNRQLRRRNSLLLSELAHMKKLYNDIIYFLQNHVAPVTTTTTTPSSTAMAAAQHHLPAAASCRLMELDSPDHSPPPPPPKTPATDGGDTVKLFGVSLHGRKKRAHRDDDDGVHDQGSEV
Protein: Intraflagellar transport protein 22 homolog (Rab-like protein 5) (Q9DAI2)
Organism: Mus musculus (Mouse)
Function: Small GTPase-like component of the intraflagellar transport (IFT) complex B.
Subcellular location: Cell projection, cilium {ECO:0000269|PubMed:19253336}.
Interaction partners:
- Intraflagellar transport protein 46 homolog
- Intraflagellar transport protein 81 homolog
- Intraflagellar transport protein 74 homolog
- Intraflagellar transport protein 52 homolog
- Intraflagellar transport protein 25 homolog
- Intraflagellar transport protein 27 homolog
- Intraflagellar transport protein 57 homolog
- TRAF3-interacting protein 1
- Intraflagellar transport protein 20 homolog
- Intraflagellar transport protein 88 homolog
Sequence:
MLKAKILFVGPCESGKTVLANFLTESSDITEYNPTQGVRILEFENPHVTSNNKGTGCEFELWDCGGDSKFESCWPALMKDAHGVVIVFNADIPSHLKEIEMWYSCFVQQQFLQDSHCMLVAHHKPGSGGERGSLALSPPLNKLKLVHSNLEEDPEEVRVEFIKYLKSIINSMSESRDREEMLIIT
Protein: Atlastin GTPase 3 (F5H6I7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MESSKPGPVQVVLVQKDQHSFELDEKALASILLQDHIRDLDVVVVSVAGAFRKGKSFILDFMLRYLYSQKESGHSNWLGDPEEPLTGFSWRGGSDPETTGIQIWSEVFTVEKPGGKKVAVVLMDTQGAFDSQSTVKDCATIFALSTMTSSVQIYNLSQNIQEDDLQQLQLFTEYGRLAMDEIFQKPFQTLMFLVRDWSFPYEYSYGLQGGMAFLDKRLQVKEHQHEEIQNVRNHIHSCFSDVTCFLLPHPGLQVATSPDFDGKLKDIAGEFKEQLQALIPYVLNPSKLMEKEINGSKVTCRGLLEYFKAYIKIYQGEDLPHPKSMLQATAEANNLAAAASAKDIYYNNMEEVCGGEKPYLSPDILEEKHCEFKQLALDHFKKTKKMGGKDFSFRYQQELEEEIKELYENFCKHNGSKNVFSTFRTPAVLFTGIVALYIASGLTGFIGLEVVAQLFNCMVGLLLIALLTWGYIRYSGQYRELGGAIDFGAAYVLEQASSHIGNSTQATVRDAVVGRPSMDKKAQ
Protein: Protein X (HBx) (Peptide X) (pX) (Q7TDY3)
Organism: Hepatitis B virus (HBV)
Subcellular location: Host cytoplasm {ECO:0000256|HAMAP-Rule:MF_04074}. Host nucleus {ECO:0000256|HAMAP-Rule:MF_04074}. Host mitochondrion {ECO:0000256|HAMAP-Rule:MF_04074}. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes. {ECO:0000256|HAMAP-Rule:MF_04074}.
Interaction partners:
Sequence:
MAARLCCQLDPARDVLCLRPVGAESRGRPLPGPLGALPPASPPVVPTDHGAHLSLRGLPVCAFSSAGPCALRFTSARRMETTVNAHRNLPKVLHKRTLGLSAMSTTDLEAYFKDCVFTEWEELGEEVRLKVFVLGGCRHKLVCSPAPCNFFTSA
Protein: ISG12a protein (Interferon, alpha-inducible protein 27) (Q9D1E1)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MAFSGTGTLVASIVSKMTSSAAMVKAGGAVSGTILAGSKGLILLTQSALGSATSALGALKVGTILSGFSASTLAASPIGAKAVVAVLGGAMTVAAVPPALSAVGFTASGIAASSLAAKMMSLSAIANGGGVPAGGLVAILQSAGAAGLSVPSTVIVGSAGSAVVASVMNICESFYPFLMGSEVADMATEVADMAIEVADISTEEALPNLSNTEKD
Protein: Leucine-rich repeat extensin-like protein 4 (AtLRX4) (LRR/EXTENSIN4) (Cell wall hydroxyproline-rich glycoprotein) (Q9LHF1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Modulates cell morphogenesis by regulating cell wall formation and assembly, and/or growth polarization.
Subcellular location: Secreted, cell wall {ECO:0000250|UniProtKB:O48809}.
Interaction partners:
- Protein RALF-like 1
- Ferritin-4, chloroplastic
- Pentatricopeptide repeat-containing protein At5g15300
- AT5g43460/MWF20_18
- Actin-related protein 4
Sequence:
MKNNTTQSLLLLLLFFFFFFEISHSLSISSNAPLSDTEVRFIQRRQLLYYRDEFGDRGENVTVDPSLIFENPRLRSAYIALQAWKQAILSDPNNITVNWIGSNVCNYTGVFCSKALDNRKIRTVAGIDLNHADIAGYLPEELGLLTDLALFHVNSNRFCGTVPHKFKQLKLLFELDLSNNRFAGKFPTVVLHLPSLKFLDLRFNEFEGTVPKELFSKNLDAIFINHNRFRFELPENFGDSPVSVIVLANNHFHGCIPTSLVEMKNLNEIIFMNNGLNSCLPADIGRLKNVTVFDVSFNELVGPLPESVGGMVEVEQLNVAHNLLSGKIPASICQLPKLENFTYSYNFFTGEAPVCLRLSEFDDRRNCLPGRPAQRSSRQCSAFLSRPSVDCGSFGCGRSVVKPSPPIVALPPPPPPSPPLPPPVYSPPPSPPVFSPPPSPPVYSPPPPPSIHYSSPPPPPVHHSSPPPPSPEFEGPLPPVIGVSYASPPPPPFY
Protein: Anaphase-promoting complex subunit 16 (APC16) (Cyclosome subunit 16) (Q96DE5)
Organism: Homo sapiens (Human)
Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:20360068}. Nucleus {ECO:0000269|PubMed:20360068}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:20813266}.
Interaction partners:
- Anaphase-promoting complex subunit 10
- Anaphase-promoting complex subunit CDC26
- Anaphase-promoting complex subunit 7
- Anaphase-promoting complex subunit 1
- Cell division cycle protein 23 homolog
- Cell division cycle protein 27 homolog
- Anaphase-promoting complex subunit 5
- Cell division cycle protein 20 homolog
- Cell division cycle protein 16 homolog
- Anaphase-promoting complex subunit 15
Sequence:
MAASSSSSSAGGVSGSSVTGSGFSVSDLAPPRKALFTYPKGAGEMLEDGSERFLCESVFSYQVASTLKQVKHDQQVARMEKLAGLVEELEADEWRFKPIEQLLGFTPSSG