wanglab/gogpt-training-data huggingface dataset:
Protein: ELL-associated factor 2 (Testosterone-regulated apoptosis inducer and tumor suppressor protein) (Q96CJ1)
Organism: Homo sapiens (Human)
Function: Acts as a transcriptional transactivator of TCEA1 elongation activity (By similarity). Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. Potent inducer of apoptosis in prostatic and non-prostatic cell lines. Inhibits prostate tumor growth in vivo.
Subcellular location: Nucleus speckle {ECO:0000269|PubMed:12446457, ECO:0000269|PubMed:12907652}.
Interaction partners:
- RNA polymerase II elongation factor ELL
- RNA polymerase II elongation factor ELL3
- AF4/FMR2 family member 4
- ELL-associated factor 1
- RNA polymerase II elongation factor ELL2
- Little elongation complex subunit 2
- Transcription elongation factor A protein 2
- Transcription elongation factor SPT5
- Protein ENL
- Transcription elongation factor SPT4
Sequence:
MNSAAGFSHLDRRERVLKLGESFEKQPRCAFHTVRYDFKPASIDTSSEGYLEVGEGEQVTITLPNIEGSTPPVTVFKGSKKPYLKECILIINHDTGECRLEKLSSNITVKKTRVEGSSKIQYRKEQQQQQMWNSARTPNLVKHSPSEDKMSPASPIDDIERELKAEASLMDQMSSCDSSSDSKSSSSSSSEDSSSDSEDEDCKSSTSDTGNCVSGHPTMTQYRIPDIDASHNRFRDNSGLLMNTLRNDLQLSESGSDSDD
Protein: Lectin29Ca (Q6GUW9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MYKYATCIFSIFALWNFWGVSAKKRDTSTGTNELPKAPMPYYTIENIDMHQQHWFTYNSLRQNGTLWRIGNMEQRLEMRLQSFQNQMETQLRALKQQIEPYMENVKMSNKIKMSVFKKIGSRHFYLEKQKKMPWDSAYDTCRQMGGHLANILDEKELNEIFSEETKKNYWVDINSRANDGASWISTLSGRDVPFLKWKPNLATNIHRHCVYINSNEMYFENCANDNYFACQAEQWA
Protein: Forkhead box protein I1-B (FoxI1-B) (FoxI1b) (xFoxI1b) (Fork head domain-related protein 2') (xFD-2') (xFD2') (Q91905)
Organism: Xenopus laevis (African clawed frog)
Function: Transcription factor. Essential for ventral specification of the early cephalic (head) ectoderm during gastrulation, playing a role in the 'non-neural' versus 'neural' cell fate choice. Binds to DNA via the target sequence 5'-[AG]TAAA[CT]A-3', with 5'-ATAAACA-3' being the preferred binding site.
Subcellular location: Nucleus {ECO:0000255, ECO:0000305}.
Interaction partners:
Sequence:
MNPVQQPAQHRSPASLLHLPHPKRAQEAPDMGLYCDNFMFSQQNLHPSQRAPNFSIGGEFTPPANPYLWLGGPGMNNAPNYSPAPAPYIPSAFSAPQRHFMANSAAFGGADLGWMSAASQEELLKMVRPPYSYSALIAMAIQNASDKRLTLSQIYQYVAENFPFYKKSKAGWQNSIRHNLSLNDCFKKMPRDENDPGKGNYWTLDSNCEKMFDNGNFRRKRKPKSESNNAKIAKRDEDHLNPKGKESPPMITPSSSPEVLSPTGHSKSPSPPTVTYTPCLTNFIGSMTAVDSATMNRQSPLGLLNELSQRNITGLSSFISGSAVDQSSEHQDNSLFYNRSPYYTNQKQPHFLQQLHPQQPPLYQGRY
Protein: Cilia- and flagella-associated protein 45 (Q32LN4)
Organism: Bos taurus (Bovine)
Function: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating. It is an AMP-binding protein that may facilitate dynein ATPase-dependent ciliary and flagellar beating via adenine nucleotide homeostasis. May function as a donor of AMP to AK8 and hence promote ADP production (By similarity).
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:34715025}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:37327785}. Cell projection, cilium {ECO:0000250|UniProtKB:Q9UL16}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q9UL16}. Note=Located in the proximal region of respiratory cilia. {ECO:0000250|UniProtKB:Q9UL16}.
Interaction partners:
Sequence:
MPLSTAGVLSSASTASNRSRNRPRYRTKALSSEVDESLFGAIKPLTRSDSPIVLLRDKHAIRKTLTALGLDHKPETIQLITRDMVRELIIPTKDPSGQSLIMSPEEFERIKWASHVLTKEELEAREQAFKKEKEAIVDTVTTRKKIMKQKEMVWRNNRKLSDLEEVAKERAQNLLQRANQLRMEQEEELKDMKKIILNAKCHAIRDAQILEKQLIQKELDAEEKRLDQMMEVERQKSVQRQEELDRKRREERIRGRRHIVEQMEKNQEERSLLAEQREQEKEQMLEYMEKLQEEDLRDLEQRHQQKLKMQAEIKRINDENQRQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKMETEAKLRKSRLEQVAFKEHTLAVQVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHANELRRQVRENQQKQVQARIATFDEGRRLKEEAQKRRERIEDIKRKKLEELRATGLPEKYCIEAERKANIPVNTSVN
Protein: Heat shock protein HSP 90-alpha (P11501)
Organism: Gallus gallus (Chicken)
Function: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interaction with various co-chaperone proteins or complexes, that act as adapters, simultaneously able to interact with the specific client and the central chaperone itself. Recruitment of ATP and co-chaperone followed by client protein forms a functional chaperone. After the completion of the chaperoning process, properly folded client protein and co-chaperone leave HSP90 in an ADP-bound partially open conformation and finally, ADP is released from Hsp90 which acquires an open conformation for the next cycle.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P07901}. Melanosome {ECO:0000250|UniProtKB:P07900}.
Interaction partners:
- SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
- Heat shock cognate 71 kDa protein
- Stress induced phosphoprotein 1.
- Prostaglandin E synthase 3
- Endoplasmin
- DnaJ homolog subfamily A member 1
- Uncharacterized protein.
- Heat shock 70 kDa protein 4
- Hsp90 co-chaperone Cdc37
- Mixed lineage kinase domain like pseudokinase
Sequence:
MPEAVQTQDQPMEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKDLKINLIPNKHDRTLTIVDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGSYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRLDNGEPLGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPIRLFVEKERDKEVSDDEAEEKEEEKEEKEEKTEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDEEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFMRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHVYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKAKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDTAAEEASPAVTEEMPPLEGDDDTSRMEEVD
Protein: Beta-1,4-xylosyltransferase IRX9 (EC 2.4.2.24) (Protein IRREGULAR XYLEM 9) (Xylan xylosyltransferase IRX9) (Q9ZQC6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the synthesis of the hemicellulose glucuronoxylan, a major component of secondary cell walls. Xylan xylosyltransferase that acts cooperatively with IRX14 to achieve the successive addition of xylosyl residues during xylan backbone elongation.
Subcellular location: Golgi apparatus membrane {ECO:0000305|PubMed:17322407}; Single-pass type II membrane protein {ECO:0000305|PubMed:17322407}.
Interaction partners:
- Probable beta-1,4-xylosyltransferase IRX10
- Cellulose synthase A catalytic subunit 8
- Cellulose synthase A catalytic subunit 4
- Probable galacturonosyltransferase 12
- Cellulose synthase A catalytic subunit 7
- UDP-glucuronate:xylan alpha-glucuronosyltransferase 1
- Probable glucuronoxylan glucuronosyltransferase IRX7
- Probable beta-1,4-xylosyltransferase IRX10L
- Probable galacturonosyltransferase-like 1
- Protein IRREGULAR XYLEM 15
Sequence:
MGSLERSKKKAQVWKKAVIHFSLCFVMGFFTGFAPAGKASFFSNFETTSYTSTKSPIPPQPFENATYTQHSLLNRTLINSQSQAPAPAESREAEGETRSLSEKEDENQVKVTPRGLVIVVTPIITKDRYKNVLLRRMANTLRLVPPPLLWIVVEKHSDGEEKSSSTMLRKTGIMYRRIVFKEDFTSLESELDHQRNLALRHIEHHKLSGIVHFAGLNNIYDLDFFVKIRDIEVFGTWPMALLSANRKRVVVEGPVCESSQVLGWHLRKINNETETKPPIHISSFAFNSSILWDPERWGRPSSVEGTKQDSIKYVKQVVLEDDTKLKGLPAQDCSKIMLWRLKFPTRTRLST
Protein: Elongator complex protein 4 (A0A1X7SBS0)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MAAVATCGSVAASTGSAVATASKSNVTSFQRRGPRASVTNDSGPRLVSIAGTRPSVRNGQLLVSTGLPALDQLLGGGLAVGTVLLIEEDKYNIYSPLLFKYFLAEGIVNGHTLLVASAKEDPANILQELPAPLLDDKCKKEFDEDVYNHKTPESNIKMKIAWRYQLLPKMEQIGPVSSSRFGHYYDASKRMPQELIEASNWHGFFLPEKISSTLKVEPCSLTPGYTKLLQFIQNIIYEEGFDGSNPQKKQRNILRIGIQNLGSPLWGDDICCAENGGNSHSLTKFLYVLRGLLRTSLSACIITMPTHLIQNKAIIARVTTLSDVVVGLESFIGSERETNPLYKDYHGLIHIRQIPRLNNLICDESDVKDLAFKLKRKLFTIERLHLPPDLSDTVSRSSKMDLAESAKRLGPGCGMMAGGKKHLDF
Protein: Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) (G5EF72)
Organism: Caenorhabditis elegans
Subcellular location: Cell membrane {ECO:0000256|RuleBase:RU369121}.
Interaction partners:
Sequence:
MGCVGAGADAEGREARKVNKQIEEQLAKDKQVMRATHRLLLLGAGESGKSTIVKQMRILHINGFNEAEKREKITDIRRNVRDAMQVILRAMDEIVPKVSLDDPSTAISRDYILRITNDPEDNYPSEFYDHILTCWKDKGVMACYERSSEYQLIDCAQYFLDKVDVVRQNNYDPSEQDILRCRVMTTGIFETKFEVDKVRFHMFDVGGQRDERRKWIQCFNDVTAIIFVCASSSYNLVLWEDNTQNRLRESLALFKNIWNNRWLKTISVILFLNKQDLLSEKIKAKRYLLESFFPEFEGYNLPNDAVFDNQEDKDVVRAKYFIRGEFLRISTANSDGRHHCYPHFTCAVDTENIRRVFNDCRDIIQRIHLRQYELL
Protein: ATP-binding cassette sub-family C member 5 (Multidrug resistance-associated protein 5) (E1B2R7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MKGHDLGKDCLAAGSAYRAVPSRETLPGPDGDHYELSKVQDAFETAARAEGGLSLDRGNAADAKELEEDAAGRSKYHHSVCVLKPIRSTSKYQHPVDNAGLFSFMTFNWLTSLAVLAHKKGQLFLEDIWAVSQFESCEINRRRLAGLWEEEIRSRGNDASLRRVVWHFCRTRLLLSILCLMVTQLAGFSSPAFVVWRLLEYTQRSEPDLPYGLLLVLGLLATELIRSWSHALTWALNYRTGTRLRGAILTMAFHKILRLRSLREKSMGELINMCSGDGQRMFEAAAVGSLLAGGPLVAVLGMAYNLFVLGPTSLLGSAVFILFYPTMMFSSRLTAYFRRKGVAVTDQRVQKMNEILNYIKFIKMYAWVKAFSQAVRRIRDEERQILERTGYFQSITVGVAPIVVVIASVATFSTHMLLGYDLTAAQAFTVVTVFNAMTFALKVTPFSVKSLSEASVAIDRFKSLLLMAEVKMIRELPRNPSVAVEMSGASLAWETGGHSAQPSPRGTPHVGTRGCRKKRRQRDVPKHHAILEEETHGQLLNDVSGEMASSPKDQTLHVPTISQRLQRTLHCIDLSIQKGKLVGVCGSVGSGKTSLISAILGQMTLLEGTVAVDGDFAYVAQQAWILNASFRDNILFGKEMEEERYQAILSACCLRPDLAMLPSGDLTEIGERGANLSGGQRQRISLARALYSNRGIYILDDPLSALDAHVGNHIFNNAIKKQLRGKTVIFVTHQLQYLVDCDDVIVMRDGSIAEQGSHEDLMNVNGDYAAMFNNLQLGETPIIEVPNKKSGSSLKKPLEKSKAGSVKKEKSTTQGDGQLMQVEERGKGSVPWAVYKVYIQALGGWPVFLFILALFILNVGSTAFSNWWLCYWIKQGSGNTTVQVGNSSVLSESMRDNPLMQHYAAVYTMSMGVMLLLKLLRGIVFVKGTLRASSRLHDELFQKILRSPMKFFDTTPTARILNRFSKDMDEVDTRLPFQAEMFTQNVILVLFCLAVIGSVFPWFLVAVGPLVLLFTVLHVVSRVFIRELKRLDNVTQSPFLSHIASSIQGLTTVHAYGKEDEFLHRYQELLDQNQAPFYLFSCAMRWLAVRLDVISVALISITALMIVLMHGQIPPAYAGLAISYAVQLTGLFQFTVRLASETEARFTSVERIHHYIKSLSLEAPARVKNKAPPSDWPQEGEIVFDQTEMKYRDNLPLILKKASFTVRPKEKIGIVGRTGSGKSSLGVVLYRLVEPCGGSIKIDGVNICDIGLADVRSKLSIIPQEPVLFSGTVRSNLDPFSQYSEAQIWDALERTHMKECVSQLPLKLESEVVENGENFSVGERQLLCVARVLLRQCKILILDEATAAMGTETDCLIQETIRNAFQDCTTLTIAHRVHTVLSCDRIMVLNQGQVVEFDEPSKLLANENSRFCAMLAAVENKISVRG
Protein: F-box protein At5g03100 (Q501G5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At4g12735
- Transmembrane protein, putative
- Probable serine/threonine-protein kinase PBL23
- Plant invertase/pectin methylesterase inhibitor superfamily protein
- Beta-glucosidase 8
- Serine carboxypeptidase-like 20
- Amine oxidase [copper-containing] zeta, peroxisomal
- Peroxisomal fatty acid beta-oxidation multifunctional protein AIM1
Sequence:
MKRAGGGVDFISSLPDEILHHILANTPTKLAIRTSVLSKRWKHVWYETPSISIVCNRVDPDSLNKTLSSYSTPKIKSFDVTISRDVTVPEIDTWINLALSRKAENVSLRFTSHYRFRDTFFINSSLKQLSLTLVYCILNPKCVVSWSSLRNLSLNRCKVSDDSIAKILTGCSLLESLTLNLCDRLNDLDLSKSLSLRRLEILGDRWTPERIVAPHIRYLRLENYQRPSTLVDVSSLTEANLGLSKHVLDYFTCEMETESLQYMVRQTVVKLQNIKKLTIGGIFLQILSLAELCGVTLPVFQNSISKL
Protein: Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34) (Q62193)
Organism: Mus musculus (Mouse)
Function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. Through recruitment of ATRIP activates the ATR kinase a master regulator of the DNA damage response. It is required for the recruitment of the DNA double-strand break repair factors RAD51 and RAD52 to chromatin in response to DNA damage. Also recruits to sites of DNA damage proteins like XPA and XPG that are involved in nucleotide excision repair and is required for this mechanism of DNA repair. Also plays a role in base excision repair (BER) probably through interaction with UNG. Also recruits SMARCAL1/HARP, which is involved in replication fork restart, to sites of DNA damage. May also play a role in telomere maintenance.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P15927}. Nucleus, PML body {ECO:0000250|UniProtKB:P15927}. Note=Redistributes to discrete nuclear foci upon DNA damage in an ATR-dependent manner. {ECO:0000250|UniProtKB:P15927, ECO:0000269|PubMed:17141802}.
Interaction partners:
- Replication protein A 14 kDa subunit
- Replication protein A 70 kDa DNA-binding subunit
- RecQ-like DNA helicase BLM
- DNA topoisomerase 3-alpha
- RecQ-mediated genome instability protein 1
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1
- DNA repair protein RAD52 homolog
- Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN
- DNA primase small subunit
- DNA topoisomerase 3-beta-1
Sequence:
MWNSGFESFSSSTYGGAGGYTQSPGGFGSPTPSQAEKKSRVRAQHIVPCTISQLLSATLTDEVFRIGDVEISQVTIVGIIRHAEKAPTNIVYKIDDMTAPPMDVRQWVDTDDASGENAVVPPETYVKVAGHLRSFQNKKSLVAFKIIPLEDMNEFTAHILEVVNSHMMLSKPNSQASAGRPSMSNPGMSEPGNFSGNNFMPANGLTVVQNQVLNLIKACPRPEGLNFQDLRSQLQHMPVPSIKQAVDFLCNEGHIYSTVDDDHFKSTDAE
Protein: Pleiotrophin (PTN) (Q502U6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU369117}.
Interaction partners:
- ALK tyrosine kinase receptor
- Protein tyrosine phosphatase receptor type Z1a.
- Protein tyrosine phosphatase receptor type Z1b.
- Tyrosine-protein kinase receptor
- Syndecan
- Midkine
Sequence:
MQQQWVCVALLALLTVTATLADGGKTEKQGKKERKSDCGEWQWSVCVANEGDCGLGTREGTRSGNDCKQTIKTQRCKIPCNWKKQFGGECKYDFQAWGECDSTTGMKTRTGVLKRALMDANCPNTVSATKPCGKPKTKMQDSQKPKRDGKKKERNPTD
Protein: Cytochrome P450 307a1 (EC 1.14.-.-) (CYPCCCVIIA1) (Protein spook) (Q9VRM7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Required for correct development of the embryonic midline glial cells which are necessary for the formation of distinct segmental commissures.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. Microsome membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.
Interaction partners:
- Cholesterol 7-desaturase nvd
- Cytochrome P450 315a1, mitochondrial
- Cytochrome P450 306a1
- Spookier
- Short-chain dehydrogenase/reductase)
- Halo
- Cytochrome P450 302a1, mitochondrial
- Scavenger receptor class C, type II, isoform A
- Ecdysone receptor
Sequence:
MLAALIYTILAILLSVLATSYICIIYGVKRRVLQPVKTKNSTEINHNAYQKYTQAPGPRPWPIIGNLHLLDRYRDSPFAGFTALAQQYGDIYSLTFGHTRCLVVNNLELIREVLNQNGKVMSGRPDFIRYHKLFGGERSNSLALCDWSQLQQKRRNLARRHCSPREFSCFYMKMSQIGCEEMEHWNRELGNQLVPGEPINIKPLILKACANMFSQYMCSLRFDYDDVDFQQIVQYFDEIFWEINQGHPLDFLPWLYPFYQRHLNKIINWSSTIRGFIMERIIRHRELSVDLDEPDRDFTDALLKSLLEDKDVSRNTIIFMLEDFIGGHSAVGNLVMLVLAYIAKNVDIGRRIQEEIDAIIEEENRSINLLDMNAMPYTMATIFEVLRYSSSPIVPHVATEDTVISGYGVTKGTIVFINNYVLNTSEKFWVNPKEFNPLRFLEPSKEQSPKNSKGSDSGIESDNEKLQLKRNIPHFLPFSIGKRTCIGQNLVRGFGFLVVVNVMQRYNISSHNPSTIKISPESLALPADCFPLVLTPREKIGPL
Protein: Immunity protein SdpI (O32241)
Organism: Bacillus subtilis (strain 168)
Function: Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor/signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Transcriptional repressor SdpR
- Sporulation delaying protein C
- Uncharacterized protein YfhL
- Putative DNA-binding protein YizB
Sequence:
MKKNIISIIIVCLSFLTSIILYQYLPEEIPIQWSGNKPAAIVSKPLTIFIIPVVMLIYYLTFYMLTIKSTQKNKALLFLASNNMLILLYILQLSTLLISLGYEVNIDLIIGLGVGIFLIIGGNSMQLAEQNHLIGLRTPWTLKDETVWKLGNRFASKVLVVCGFIIAVLSFFTGEYIILIMIVLVLLALVISTLASYHYYKKLNGSR
Protein: ARM repeat superfamily protein (F4K790)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
Interaction partners:
- Structural maintenance of chromosomes protein 2-1
- Condensin-1 complex subunit CAP-D2
- Condensin complex subunit 2
- Structural maintenance of chromosomes protein 2-2
- Structural maintenance of chromosomes protein 4
- Structural maintenance of chromosomes protein
- Mitogen-activated protein kinase kinase kinase 21
- Structural maintenance of chromosomes protein 3
- Structural maintenance of chromosomes protein 1
- Serine/threonine-protein kinase MPS1
Sequence:
MGEESEIAMASADRNNLTQKIAKILNETRTSYATHNRKLKELATIRSKLSSSESESESVSSSILQFSSVFLKTLTPLFIAAQRRTAAAERVVRFVAEFACLRSNSDGDSDCDEFLEEFLKFLVAGSVAANRNARFRACQIISEIILRLPDEVEVADELWDDVIDCMMLRVRDKVPVIRTFAVRSLSRFVNDPENSDILDLLLEVLPLEQNPEVRKTIVLSLPPSNATTQAIIDCTLDVNESVRKAAYSVLANKVPLQSLSIKLRTTILQRGLADRAVNVSTECLKLMKEQWLANYCEGDPITFLKYLDVETYESVAESALEVLLSEGLIMPSDDKSIQQYILSADGETRDESTCSAPSIQLMEPEIALYWRIICRKVHQSAQAKGSDAATAMGAEAAVYAAEASDANDLLERILPATVSDYVDLVKAHIEAGPNHHFASRQLLLLGTMLDFSDAMLHKTVSSFVQELLRRPFEQELDEDGNSIVIGDGINLGGDKDWAEAVSKLAKKVHAAPGEYEEVILVVVEEVARPCRERTADFLQWMHMLSLTSLLLENGKSLHSLQGKAIEPEEILHALLLPGAKHTHLDVQRIAIKGLGLFGLLEKKPSEELVRQLRAAFCRSPPPISIMACKALVDLGMWHSPTEVDKAMGQDLLSQFEDDSIDFAPIDLSNAEEDMNFKMLDLLYAGLESDDWRASTESSENESVKATVGEGFAKLLLLGEKYPNLPASFYPFVLGKLIALYFSEESKEQLRFKQCLSVFFEHYASLSEKHKGYVSKAFVPLVRSMWPGIDGNTKSSSYVVSNQRKRAVQVSRFILQMMQTPLYKKETRGEPESQVNKSPEDSIQHPLNCTEEGLAIRIAIEMLSFKEKKTAHEKAYVAALCKILVLLHLKPSEQNVTKLLKKLLSLLADSVRSEKDLLKEVKPVLQHLKSLDACPSEELTQDQANSIFEILGVSYNLEITETTTVPQTPAPCSTKPARSRRRARIEETSSDEEEVASPPPSAPNTLMTRSHRASKAAALAKIMASKVKMSNVDEDDEEEEGSSDVTADDSDE
Protein: Fasciclin-2 (Fasciclin II) (FAS II) (P34082)
Organism: Drosophila melanogaster (Fruit fly)
Function: Neuronal recognition molecule for the MP1 axon pathway, pathway recognition for axons during the development of nerve fascicles.
Subcellular location: [Isoform 1]: Cell membrane {ECO:0000305|PubMed:1913818}; Single-pass type I membrane protein {ECO:0000255}.; SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane {ECO:0000269|PubMed:1913818}; Lipid-anchor, GPI-anchor {ECO:0000305|PubMed:1913818}.
Interaction partners:
- Fasciclin-1
- Protein elav
- Bruchpilot, isoform J
- Fasciclin-3
- Semaphorin-1A
- Neuroglian
- Microtubule-associated protein futsch
- Glutamate receptor IIA
- Beaten path Ia, isoform B
- Disks large 1 tumor suppressor protein
Sequence:
MGELPPNSVGVFLALLLCSCSLIELTRAQSPILEIYPKQEVQRKPVGKPLILTCRPTVPEPSLVADLQWKDNRNNTILPKPNGRNQPPMYTETLPGESLALMITSLSVEMGGKYYCTASYANTEILEKGVTIKTYVAITWTNAPENQYPTLGQDYVVMCEVKADPNPTIDWLRNGDPIRTTNDKYVVQTNGLLIRNVQESDEGIYTCRAAVIETGELLERTIRVEVFIQPEIISLPTNLEAVEGKPFAANCTARGKPVPEISWIRDATQLNVATADRFQVNPQTGLVTISSVSQDDYGTYTCLAKNRAGVVDQKTKLNVLVRPQIYELYNVTGARTKEIAITCRAKGRPAPAITFRRWGTQEEYTNGQQDDDPRIILEPNFDEERGESTGTLRISNAERSDDGLYQCIARNKGADAYKTGHITVEFAPDFSHMKELPPVFSWEQRKANLSCLAMGIPNATIEWHWNGRKIKDLYDTNLKIVGTGPRSDLIVHPVTRQYYSGYKCIATNIHGTAEHDMQLKEARVPDFVSEAKPSQLTATTMTFDIRGPSTELGLPILAYSVQYKEALNPDWSTAYNRSWSPDSPYIVEGLRPQTEYSFRFAARNQVGLGNWGVNQQQSTPRRSAPEEPKPLHNPVQHDKEEPVVVSPYSDHFELRWGVPADNGEPIDRYQIKYCPGVKISGTWTELENSCNTVEVMETTSFEMTQLVGNTYYRIELKAHNAIGYSSPASIIMKTTRGIDVIQVAERQVFSSAAIVGIAIGGVLLLLFVVDLLCCITVHMGVMATMCRKAKRSPSEIDDEAKLGSGQLVKEPPPSPLPLPPPVKLGGSPMSTPLDEKEPLRTPTGSIKQNSTIEFDGRFVHSRSGEIIGKNSAV
Protein: HAlF transporter (PGP related) (O45278)
Organism: Caenorhabditis elegans
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Ubiquitin-like protein 5
- Homeobox protein dve-1
- Stress activated transcription factor atfs-1
- Heat shock protein hsp-6
- ATP-dependent Clp protease proteolytic subunit 1, mitochondrial
- Chaperonin homolog Hsp-60, mitochondrial
- Ubiquitin-like protein
- AFG3-like protein spg-7
Sequence:
MHCLCVLRSTLCCQMPTSTYRMLLQTKAVPVQIIKRDLTAKVKNQKLNQNIRRVDRRNAAYLLRHTTWKDLVELYEIAKPFRKWIFLGTSFMVVSSGIFLIIPRILGKLIDQFDSNTGVQKAEEVFTMKIAKYFKEQPMSLVGLLAIGALATAAKVYCLQIAGVNIVGSLRKMVYSSIIRQDMTFFDKNMVGEIGSRHAADTVIVGYSVSSSLRAGVRAVLVGVGSIGMMLMTSLELSTVSFLTAPIVMGIFKMFGRVQQQCTWQLQEVAADVNQTAIERMANMKTIRMLSAEQQSIDEYCKKGELVLDISKTEALAKGSLIGSFQFTGYSAFSSILFYGSHLINTGHITYGELSSFCLYAVLAAASLSNISGFYNEVMKGLGASSRLLELKNAQPIMNLNSGIKKTDITTSIQFENVSFAYAGRKKTLENISFDIPRGKITAVIGPSGSGKSSIANLMLRLYDPADGRVTVDGVDLRDLNATTWRHAIGTVGQEPVLFTCSIRENILMGTEHPEKVSQYELEEAAQLANALDFIQGFENGFETMVGEHGCKLSGGQKQRIAIARALISKPKIMILDEATSALDATSDYLIRMTLDNLLKNHNLTVLVIAHRLATMQQADQVVYVNRGRIEGQGTFDEMMKIQNSIVEQEARRRGIPMNEQMSRVNTPVARGFSLKF
Protein: Semaphorin-like protein 139 (Q8JL80)
Organism: Ectromelia virus (strain Moscow) (ECTV) (Mousepox virus)
Function: Acts as a semaphorin-like protein and binds to host plexin C1 receptor. May alter the movement of plexin C1-expressing cells including dendritic cells, monocytes, or granulocytes in the proximity of infected cells. May also regulate host cell cytoskeleton of neighboring cells to improve viral infection.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
Sequence:
MIPLLFILFYFTNCIEWHKFETSEEIISTYLIDDVLYTGVNGAVYTFSNNELNKTGLTNNNNYITTSIKVEDTLVCGTNNGNPKCWKIDGSEDPKYRGRGYAPYQNSKVTIISHNECVLSDINISKEGIKRWRRFDGPCGYDLYTADNVIPKDGVRGAFVDKDGTYDKVYILFTDTIDTKRIVKIPYIAQMCLNDEGGPSSLSSHRWSTFLKVELECDIDGRSYRQIIHSKAIKTDNDTILYVFFDSPYSKSALCTYSMNAIKHSFSTSKLGGYTKQLPSPAPGICLPAGKVVPHTTFDIIEQYNELDDIIKPLSQPIFEGPSGVKWFDIKEKENEHREYRIYFIKENTIYSFDTKSKQTRSAQVDARLFSVMVTSKPLFIADIGIGVGIPRMKKILKM
Protein: Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase X) (DPP X) (Kv4 potassium channel auxiliary subunit) (Q6Q629)
Organism: Rattus norvegicus (Rat)
Function: Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity (Probable).
Subcellular location: Cell membrane {ECO:0000269|PubMed:16123112}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- A-type voltage-gated potassium channel KCND3
- Potassium voltage-gated channel subfamily A member 4
- IgLON family member 5
- Calsenilin
- Voltage-gated potassium channel KCNC1
- Leucine-rich glioma-inactivated protein 1
- A-type potassium channel modulatory protein KCNIP1
- A-type voltage-gated potassium channel KCND1
- A-type potassium channel modulatory protein KCNIP2
- Delta and Notch-like epidermal growth factor-related receptor
Sequence:
MNQTASVSHHIKCQPSKTIKELGSNSPPQRNWKGIAIALLVILVVCSLITMSVILLTPDELTNSSETRLSLEELLGKGFGLHNPEARWINDTDVVYKTDNGHVMKLNAETNATTLLLDNSTFVTFKASRHSLSPDLKYVLLAYDVKQIFHYSFTASYLIYNIHTGEVWELNPPEVEDSVLQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGKEGIVFNGIADWLYEEELLHSHIAHWWSPDGERLAFLMINDSLVPNMVIPRFTGALYPKAKQYPYPKAGQANPSVKLYVVNLYGPTHTLELMPPDIFKSREYYITMVKWVSNTRTVVRWLNRPQNISILTVCESTTGACSRKYEMTSDTWISKQNEEPVFSRDGSKFFMTVPVKQGGRGEFHHIAMFLVQSKSEQITVRHLTSGNWEVIRILAYDETTQKIYFLSTEFSPRGRQLYSASTEGLLSRDCISCNFRKEDCTYFDASFSPMNQHFLLFCEGPKVPMVSLHSTDNPSNYYILERNSMMKETIQKKKLAKREIRILHIDDYELPLQLSFPKDFLEKNQYALLLIIDEEPGGQMVTEKFHVDWDSVLIDTDNVIVARFDGRGSGFQGLKVLQEIHRRTGSVEAKDQIAAIKYLLKQPYIDSKRLSIFGKGYGGYIASMILKSDEKFFKCGTVVAPISDMKLYASAFSERYLGMPSKEESTYQASSVLHNIHGLKEENLLIIHGTADTKVHFQHSAELIKHLIKAGVNYTLQVYPDEGYHISDKSKHHFYSTILRFFSDCLKEEVSVLPQEPEEDE