wanglab/gogpt-training-data huggingface dataset:
Protein: Transmembrane protein, putative (DUF3317) (F4IPU5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}.
Interaction partners:
Sequence:
MNWVQRKIYLYNVTFGLYMLDWWERYLFNSLVLILMWFILYNGSRYFSELCKRHLS
Protein: Small ribosomal subunit protein uS4c (30S ribosomal protein S4, chloroplastic) (P56799)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Small ribosomal subunit protein eS7y
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Small ribosomal subunit protein uS11c
- Large ribosomal subunit protein bL28c
- Small ribosomal subunit protein eS30z/eS30y/eS30x
- Small ribosomal subunit protein uS15c
- Small ribosomal subunit protein uS2c
- Large ribosomal subunit protein uL18y
- Large ribosomal subunit protein eL38z/eL38y
- Small ribosomal subunit protein uS14c
Sequence:
MSRYRGPRFKKIRRLGALPGLTSKRPKAGSDLRNQSRSVKKSQYRIRLEEKQKLRFHYGLTEHQLLKYVRIAGKAKGSTGQVLLQLLEMRLDNILFRLGMALTIPQARQLVNHGHILVNGRIVDIPSYRCKPRDIITVKDEQNSRTLVQNLLDSSAPEELPNHLTLHTFQYEGLVNQIIDRKCVGLKINELLVVEYYSRQT
Protein: Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD-M) (GPDH-M) (EC 1.1.5.3) (O14400)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion {ECO:0000250}.
Interaction partners:
- Glycerol-3-phosphate dehydrogenase [NAD
- Glycerol-3-phosphate dehydrogenase [NAD
- Dihydroxyacetone kinase 1
- Dihydroxyacetone kinase 2
- Probable diacylglycerol pyrophosphate phosphatase 1
- Uncharacterized acyltransferase C1718.04
- Glycerol dehydrogenase 1
- Xylulose kinase
- Uncharacterized acyltransferase C1851.02
- Putative lysophosphatidic acid:oleoyl-CoA acyltransferase
Sequence:
MFSIFKRRSVQAALAASGLVGGAVFYSDFIKRPAPSHFNPQFTPFTKSLAPPPSRETLLKNVEDISKFDVLIIGGGATGTGVAVDASTRGLNVCLLEKTDFASETSSKSTKMAHGGVRYLEKAVFQLSKAQLDLVIEALNERANMLRTAPHLCTVLPIMIPVYKWWQVPYFFVGCKIYDWVAGSKNLRASTIFSKETTVAIAPMLDDSNLKASCVYHDGSFNDTRMNTTLAVTAIDNGATVLNYMEVKKLLKSKDNKLEGVLAIDRETGKEYQIKATSVVNATGPFSDKILEMDADPQGEPPKTAQFPRMVVPSAGVHVVLPEYYCPPNIGILDPSTSDNRVMFFLPWQGKVIAGTTDKPLSSVPTNPTPSEDDIQLILKELQKYLVFPVDREDVLSAWCGIRPLVRDPSTVPPGTDPTTGETQGLVRSHFIFKSDTGLLTISGGKWTTYREMAEETVNELIKDHDFGKALKPCQTKKLILVGGENYYKNYSARLIHEYHIPLRLAKHLSHNYGSRAPLILELYSKTDFNKLPVTLADKEVFAPSSDASSDKSVSYASFDEPFTVAELKYSIKYEYTRTPTDFLARRTRLAFLDARQALQAVAGVTHVMKEEFGWDDATTDKLAQEARDYIGGMGVSSDRFDVKQFEVK
Protein: Voltage-dependent calcium channel gamma-7 subunit (Neuronal voltage-gated calcium channel gamma-7 subunit) (Transmembrane AMPAR regulatory protein gamma-7) (TARP gamma-7) (P62956)
Organism: Mus musculus (Mouse)
Function: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization (By similarity). Shows specificity only for GRIA1 and GRIA2 (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P62955}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Voltage-dependent calcium channel gamma-1 subunit
- Disks large homolog 4
- Voltage-dependent calcium channel subunit alpha-2/delta-2
- Protein cornichon homolog 2
- Oxytocin receptor
- Voltage-dependent calcium channel gamma-6 subunit
- Voltage-dependent T-type calcium channel subunit alpha
- Voltage-dependent L-type calcium channel subunit alpha-1D
- Voltage-dependent R-type calcium channel subunit alpha-1E
- Voltage-dependent N-type calcium channel subunit alpha-1B
Sequence:
MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWRVCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAASSFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQPEAWRRGRSPSDISSDVSIQMTQNYPPAIKYPDHLHISTSPC
Protein: SAUR-like auxin-responsive protein family (A0A1I9LQF0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Auxin-responsive protein IAA10
- Auxin-responsive protein IAA20
Sequence:
MYFTIVLLITKPSLSLFYSSFIFETSHSILKMKNKFIKSCENKFRIMKSKSIVLPCCTSSCESCCDKVSWGFKKENEAIPKDVPRGHLVVYVGDDYKRFVIKMSLLTHPIFKALLDQAQDAYNSSRLWIPCDENTFLDVVRCSGAPQHQRNCIGM
Protein: Interleukin-18 (IL-18) (D1M7B0)
Organism: Gallus gallus (Chicken)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|PIRNR:PIRNR015162}.
Interaction partners:
Sequence:
MSCEEIAVCAVRLRENLCLYFEDDELECDAFCKDKTIKRFFRNVNSQLLVVRPDLSVAAFEDVTDQEVKSGSGMYFDIHCYKTTAPSAGMPVAFSVQVEDKSYYMCCEKEHGKMVVRFREGEVPKDIPGESNIIFFKKTFTSCSSKAFKFEYSLEQGMFLAFEEEDSLRKLILKKLPREDEVDETTKFVTSHNERHNL
Protein: tRNA nucleotidyltransferase cca1 (EC 2.7.7.-) (CC-adding enzyme cca1) (tRNA cytidyltransferase cca1) (Q9UTQ0)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: tRNA nucleotidyltransferase involved in the synthesis of the tRNA CCA terminus. In contrast to what is usually observed in eukaryotes for which one enzyme synthesizes the whole tRNA CCA terminus, in S.pombe, cca1 specifically adds two cytidine residues to a tRNA substrate lacking this sequence while cca2 specifically adds the terminal adenosine residue thereby completing the CCA sequence.
Interaction partners:
- Glutamyl-tRNA
- tRNA
- Exportin-T
Sequence:
MASSSSILELNETEKELSDIFLNVSKKIGQMDRKEPEVRFAGGWVRDKLLRIESHDIDVAIDCMSGFEFAQHLQSYLAQQHPDWETKVIKIDANPLKSKHLETATARIMGMDIDIVNLRHHDYTNSNSSNKLVFGTPLEDALRRDATINALFYNLKSKTVEDFTGKGLVDLSNKIIRTPLVADETFGDDPLRAVRCIRFATKYDFNIHEETIKGLKNPELHERLRSSISRERIGVEVDKMLKHCNTNRALKIIHSLGMFACIFGPLEIHTKKLQSKNIESLSLIPYAIDLFGYLQKKDVSIKNLSSSSKYIFWLAIATLPWYNWSILEKSKIKILPPILIRDSLKYSKPIMSQVENFFVHYPLIMSKINVLEKEGKLTRLGCGRLVRELGPHWRDIIDWAFFMNTLISNSDIQRLNKDEEVTWFHVLVKHIEEYGMEEAYNIQPIINGNEITRILGIRPGPHLRKMLDDSIEWRIQNPESTKEDYIAIMLEKGTSAVVDS
Protein: Alpha-methylacyl-CoA racemase (D6RB81)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MALQGISVVELSGLAPGPFCAMVLADFGARVVRVDRPGSRYDVSRLGRGKRSLVLDLKQPRGAAVLRRLCKRSDVLLEPFRRGVMEKLQLGPEILQRENPRLIYARLSGFGQSGSFCRLAGHDINYLALSGVLSKIGRSGENPYAPLNLLADFAGGGLMCALGIIMALFDRTRTGKGQVIDANMKLSLWEAPRGQNMLDGGAPFYTTYRTADGEFMAVGAIEPQFYELLIKGLGLKSDELPNQMSMDDWPEMKKKFADVFAEKTKAEWCQIFDGTDACVTPVLTFEEVVHHDHNKERGSFITSEEQDVSPRPAPLLLNTPAIPSFKRDPFIGEHTEEILEEFGFSREEIYQLNSDKIIESNKVKASL
Protein: Heat shock protein (A0A0H3LH87)
Organism: Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)
Interaction partners:
Sequence:
MATTLPVQRHPRSLFPEFSELFAAFPSFAGLRPTFDTRLMRLEDEMKEGRYEVRAELPGVDPDKDVDIMVRDGQLTIKAERTEQKDFDGRSEFAYGSFVRTVSLPVGADEDDIKATYDKGILTVSVAVSEGKPTEKHIQIRSTN
Protein: Probable E3 ubiquitin-protein ligase LUL4 (EC 2.3.2.27) (Probable RING-type E3 ubiquitin transferase LUL4) (Protein LOG2-LIKE UBIQUITIN LIGASE 4) (RING finger protein 208) (Q8LA32)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates (in vitro).
Interaction partners:
- DNA-binding protein BIN4
- Zinc finger CCCH domain-containing protein 34
- Probable manganese-transporting ATPase PDR2
Sequence:
MGISFSNNNRRRDNNNRRHLHHYPPPPPYYYLDPPPPPPPFPPHYDYNYSNYHLSPPLPPQPQINSCSYGHYHYHPQPPQYFTTAQPNWWGPMMRPAYYCPPQPQTQPPKPYLEQQNAKKVRNDVNVHRDTVRLEVDDLVPGHHLVSFVFDALFDGSFTITFFAKEEPNCTIIPQFPEVYSPTRFHFQKGPGQKFLQPSGTGTDLSFFVLDDLSKPLEEDVYPLVISAETIISPNSISEQSSVHKQVTQAVLEKDNDGSFKVKVVKQILWIEGVRYELRELYGSTTQGAASGLDESGSGTECVICMTEAKDTAVLPCRHLCMCSDCAKELRLQSNKCPICRQPIEELLEIKMNSSDEQH
Protein: V-set and immunoglobulin domain containing 4 (F7FEU1)
Organism: Rattus norvegicus (Rat)
Interaction partners:
- Complement C1q subcomponent subunit A
- Complement C1q subcomponent subunit C
- Scavenger receptor cysteine-rich type 1 protein M130
- C-type lectin domain family 4 member F
- Membrane spanning 4-domains A4A
- Macrophage colony-stimulating factor 1 receptor
- Complement C3
- Complement C4A.
- Complement C4
Sequence:
MEISSSLLFLSHLIVLTYGHPVLKTPERVTGTWKGDVKIQCIYNPLTGYREVLVKWLVQRGSDHVTIFLRDYSGDHVQQAKYRGRLKVSHKVPGDVSLQLNNLQMDDRNHYTCEVTWQTPDGDQVRRDKITELRVQKYPYKPPKITTEALTTMQSSLEATTITSSTSDWTTSVTQTPQGTTTVPGGKLPIFAIILIICFCCIVVVTIAFIMFRRRTFQEYVYEVSRMYARQTSNSEETTRVTTIASAYFNNEPDSQALINDYSDDPCLSQEYQITTRSTMTIPAC
Protein: MAPK-interacting and spindle-stabilizing protein-like (Mitogen-activated protein kinase 1-interacting protein 1-like) (Q8NDC0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSDEFSLADALPEHSPAKTSAVSNTKPGQPPQGWPGSNPWNNPSAPSSVPSGLPPSATPSTVPFGPAPTGMYPSVPPTGPPPGPPAPFPPSGPSCPPPGGPYPAPTVPGPGPTGPYPTPNMPFPELPRPYGAPTDPAAAGPLGPWGSMSSGPWAPGMGGQYPTPNMPYPSPGPYPAPPPPQAPGAAPPVPWGTVPPGAWGPPAPYPAPTGSYPTPGLYPTPSNPFQVPSGPSGAPPMPGGPHSYH
Protein: Protein Wnt (Q3L248)
Organism: Gallus gallus (Chicken)
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
Interaction partners:
Sequence:
KESAFVYAVTAAGLVHAVTRSCSAGNVTECSCDTKLQGGGSASEGWHWGGCSDDIHYGMAFSRSFLDAPIRNASGKSGNGLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKTMSSFEKIGRFLKDKYENSIQVSDKLKKKLRRKEKSQRKIPIQKEDLLYVNKSPNYCVEDQKLGIPGTQGRECNRTSDGPDGCNLLCCGRGYNTHVVRHVERCECKFVWCCYVRCRRCETMTDVHTCK
Protein: Subtilase-type protease inhibitor (P61152)
Organism: Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Function: Strong inhibitory activity toward subtilisin BPN' and, to a lesser extent, toward trypsin.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Secreted serine protease
- Secreted protein
Sequence:
MRNTARWAATLGLTATAVCGPLAGASLASPATAPASLYAPSALVLTVGHGESAATAAPLRAVTLTCAPTASGTHPAAAAACAELRAAHGDPSALAAEDSVMCTREYAPVVVTVDGVWQGRRLSYERTFANECVKNAGSASVFTF
Protein: Acyl-CoA-binding protein (ACBP) [Cleaved into: SDF-2] (Q5FXM5)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Binds to acyl-CoA. Processed into the SDF-2 (spore differentiation factor 2) a peptide which triggers sporulation. SDF-2 appears to stimulate prestalk cells to release additional SDF-2 by acting through a signal transduction pathway that also involves dhkA, regA and PKA. Induces encapsulation of prespore cells in a dhkA-dependent manner. GABA induces the release of acbA from prespore cells and induces the exposure of tagC on the surface of prestalk cells where it can convert acbA to SDF-2. Glutamate acts as a competitive inhibitor and is also able to inhibit induction of sporulation by SDF-2.
Interaction partners:
- Golgi reassembly stacking protein
- Serine protease/ABC transporter B family protein tagC
- Hybrid signal transduction histidine kinase A
- 3',5'-cyclic-nucleotide phosphodiesterase regA
- Hybrid signal transduction histidine kinase B
- acetyl-CoA C-acyltransferase
- Peroxisomal acyl-coenzyme A oxidase 1
Sequence:
MTTFEEAAQKVKEFTKKPSNDELLSLYGLYKQGTDGDCNISEPWAVQVEAKAKYNAWNALKGTSKEDAKAKYVALYEQLATKYA
Protein: Prohibitin-1, mitochondrial (Atphb1) (O49460)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:12837548, ECO:0000269|PubMed:14671022, ECO:0000269|PubMed:17883375, ECO:0000269|PubMed:18189341, ECO:0000269|PubMed:21841088}; Single-pass type II membrane protein {ECO:0000269|PubMed:12837548, ECO:0000269|PubMed:14671022, ECO:0000269|PubMed:17883375, ECO:0000269|PubMed:18189341, ECO:0000269|PubMed:21841088}.
Interaction partners:
- Prohibitin-3, mitochondrial
- Prohibitin-4, mitochondrial
- Prohibitin-5, mitochondrial
- SPFH/Band 7/PHB domain-containing membrane-associated protein family
- NADH dehydrogenase 1 beta subcomplex subunit 7
- NADH dehydrogenase flavoprotein 1, mitochondrial
- Flotillin-like protein 3
- At5g54100
- Prohibitin-6, mitochondrial
- At5g40700
Sequence:
MNNVKVPKIPGGGAISTLLKVGIIGGLGLYGATHSLYNVEGGHRAIMFNRLVGIKDKVYPEGTHLMIPWFERPVIYDVRARPYLVESTSGSRDLQMVKIGLRVLTRPMADQLPEIYRSLGENYSERVLPSIINETLKAVVAQYNASQLITQREAVSREIRKILTERAANFNVALDDVSITNLTFGKEFTAAIEAKQVAAQEAERAKFIVEKAEQDKRSAVIRAQGEAKSAQLIGQAIANNQAFITLRKIEAAREIAQTIANSANKVYLSSDDLLLNLQGMNLDVDAKN
Protein: Pyruvylated Gal-beta-1,3-epitope synthesis protein 5 (PvGal synthesis protein 5) (Meiotically up-regulated gene 50 protein) (Q9UUJ0)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in cell wall biogenesis. Has a role in the addition of Gal-beta1,3 moeities to galactomannans and their subsequent pyruvylation. Has a role in meiosis.
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Interaction partners:
- Pyruvyl transferase 1
- Pyruvylated Gal-beta-1,3-epitope synthesis protein 2
- Beta-1,3-galactosyltransferase pvg3
- O-glycoside alpha-1,2-mannosyltransferase omh1
- Uncharacterized protein C19C7.05
Sequence:
MGLPLRIFAGNGIGGWCLRLFLFGSLILLLRPLIFYSNTTMKKLKTEYPIYHRHLSALKRNFYYTMDAQLGGIRNVVLINRPCFAASDNFLTLMGQNWYLKERNINVLSDICFPLSNNAHDSLPTFNNGSDLFNPLYFAVLNAATPARFTFHLFNHVMDSVVPFDEAKKFKVRSFPINYAEYADDECQLALKKIRPIPDKYLVSTRVLSDSRYLELSGAVVAFAPDASSSLLFELADIKQHKKTSADILIFLSKDHNLPVSFYDNYKLKYTLHFWQPPSFPDSSTIDDQAKLLFDYVVSQVVKYPYFVTDIYQIHLLGVYLNLKHVYLLENDDVEDAYYERQWMQAFQRKNVVAVAEELQTALRIIEQWKQL
Protein: Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-I p60) (Q9D0N7)
Organism: Mus musculus (Mouse)
Function: Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q13112}. Cytoplasm {ECO:0000250|UniProtKB:Q13112}. Note=DNA replication foci. Cytoplasmic in M phase. {ECO:0000250|UniProtKB:Q13112}.
Interaction partners:
- Histone-binding protein RBBP4
- Chromatin assembly factor 1 subunit A
- Histone chaperone ASF1B
- Histone chaperone ASF1A
- Histone-binding protein RBBP7
- Proliferating cell nuclear antigen
- Chromobox protein homolog 5
- DNA replication licensing factor MCM5
- Integrator complex assembly factor WDR73
- Cell division control protein 45 homolog
Sequence:
MKVITCEIAWHNKEPVYSLDFQHGATWKIHRLASAGVDTAVRIWKLERGPDGKAIVEFLSNLARHTKAVNVVRFSPTGEILASGGDDAVILLWKMNDSKEPEQIAFQDEEEAQLNKENWTVVKTLRGHLEDVYDICWATDGNLMTSASVDNTVIIWDVSKGQKISIFNEHKSYVQGVTWDPLGQYIATLSCDRVLRIYNTQKKRVAFNISKMLSGQGPEGEARSFRMFHDDSMKSFFRRLSFTPDGSLLLTPAGCMESGENVTNTTYVFSRKHLKRPIAHLPCPGKATLAVRCCPVYFELRPVAETEKASEEPSPELVNLPYRMVFAVASEDSVLLYDTQQSFPFGYVSNIHYHTLSDISWSSDGAFLAISSTDGYCTFVTFEKGELGIPLKEKPVLSIRTPDTAKKAKNQTHQGSSPGSRSVEGTPSNRTQDPSSPCTTPSPTTQSPAPSAIKDSPSAIPAGKSPLPQPSEEKTLQPAGQNMKAPQPRRVTLNTLQTWGKTAPRRINLTPLKTDTVPNPQPNSGTAPSTEEVQPEAPGEPPEEPPELKRPRLEEREGDAQNLAPDDSSKTV
Protein: Acetylcholine receptor subunit beta-type acr-2 (P48182)
Organism: Caenorhabditis elegans
Function: Non-alpha subunit of nicotinic acetylcholine receptor (nAChR). Acts in cholinergic motoneurons to regulate presynaptic neurotransmitter release, thereby ensuring normal level of excitation of cholinergic motoneurons during locomotion.
Subcellular location: Postsynaptic cell membrane {ECO:0000250|UniProtKB:Q23022}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:Q23022}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Vesicular acetylcholine transporter unc-17
- Acetylcholine receptor subunit alpha-type unc-38
- Acetylcholine receptor subunit alpha-type unc-63
- Vesicular GABA transporter
- Acetylcholine receptor subunit beta-type acr-3
- AcetylCholine Receptor
- Glutamate decarboxylase 1
Sequence:
MKKTVKILLILITVFLKVHCNGGHDDEAADFLSHTNIDDPNNSSDPNKNSDQGDTMGEDEDRLVIDLFREYNFLIRPVKNVSSPPVVVDFGVAMILLINVDEKNQILQTNVWLTMKWNDFQLAWNPAEYGNISNLHVPSDRVWLPDIVLFNNADGNYEVSFKSNVFVDHHGDVTWVPPAMFKSSCRIDVEWFPFDEQCCTLVFGSWTYNSEEVRLHWYNNIQAVQLHDYSYSGIWDVIDVPGQLVHKPDLKENKMVFNVVIRRKTLFYTVILIIPTVLMAFLSVMAFYLPVDSGEKVSLTISLLLALVVFLLLVSKILPPTSNIPLMGKYLLLAFVLNITAVVGTVVIVNIYFRSALSHKMPTWVRKVFLEFLPHLLVMKRPERIPIFNGYFVEEYCASEIFDASLVMPSMTATMLPFLQVTTNLKAASSTSSGQSSEHHENCSKWKKRLSIRMSKRRAPRARLDDDSEDIIDDTNGNHVDSLQEKISKEMKTTVEAIAYIAEHMKREMSLKKMRDDWKYVAMVLDRLILLIFFGVTLGGTLGIICSAPHVFDFVDQEAIISKLNAKYLPSDMYS
Protein: Chaperone protein dnaJ 13 (AtDjB13) (AtJ13) (Q39079)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a continuous role in plant development probably in the structural organization of compartments (By similarity). Seems to be involved in resistance to oxidative stresses mediated by thiol-oxidizing agents such as diamide.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Gamma-glutamyl peptidase 5
- Thioredoxin-like 1-2, chloroplastic
- Thioredoxin-like protein CXXS1
- Heat shock 70 kDa protein 9, mitochondrial
- Chaperone protein dnaJ 8, chloroplastic
- Heat shock 70 kDa protein 10, mitochondrial
Sequence:
MMGQEAAPTGPPNRELYALLNLSPEASDEEIRKAYRQWAQVYHPDKIQSPQMKEVATENFQRICEAYEILSDETKRLIYDLYGMEGLNSGLELGPRLSKADEIKEELERIKRRNEEAKKMAHFQPTGSILFNLSVPHFLVGDGIMRGMVMASQVQSQLSKDDAIAIGGNLAANEKSGGGVATAILRRQISPVSSIEFVASTGLQSLIGVQTTRQLTIHSTATINISKSLSDGSINLTNTWTRQLSETSSGNIELALGMRSAITVGWKKRDENVSAAGDFKIESGGLGASARYTRKLSSKSHGRIVGRIGSNALEIELGGGRQISEFSTVRMMYTVGLKGIFWKVELHRGSQKLIVPILLSAHLAPVFATGAFIVPTSLYFLLKKFVVKPYLLKREKQKALENMEKTWGQVGEARARAEKAQQLLQTVATRKKNRQVETDGLIVTKALYGDPKAIERRNEGVEGLDSGVIDVTVPMNFLVSDSGQLKLHEGVKKSGIMGFCDPCPGQPKQLYIAYTYHSQPFEVIVGDYEELSIPQEGQ
Protein: MAP kinase-interacting serine/threonine-protein kinase mnk-1 (EC 2.7.11.1) (MAP kinase integrating kinase-1) (Q8I113)
Organism: Caenorhabditis elegans
Function: Serine/threonine-protein kinase which is required in the germline to regulate positively lifespan. May play a role in body wall muscle contraction. May be involved in embryonic cytokinesis.
Subcellular location: Nucleus {ECO:0000269|PubMed:19528325}. Cytoplasm {ECO:0000269|PubMed:19528325}. Note=Predominantly localizes in the nucleus in the 1- and 2-cell embryos. {ECO:0000269|PubMed:19528325}.
Interaction partners:
- Mitogen-activated protein kinase mpk-1
- Transcription factor atf-4 homolog
Sequence:
MFFLDNTDSMTSSSRGITMPNTISSHEDVGGYSPRKVGIQHDYSAVGGGGAAFHHLHTSAATPRHVATSEFYDDEEATSPRGGIEIGAGGGKMMANLRRHRQRERETYEDEDVLSSSDESSGRPIPRYVGRDTDHVFGEFEMDDEDVVMRREDGYGEDETDEDYFDEEEPVAELLPLGGGTRRVPRTPGRKNSSKCGFFDYYKLTDEHLGSGAYGSVTTCKSIKSGVEYAVKIVDKQGETHSRKRILREVNIFKTCKDHPNIVQLLDWFEDETNFYLVMEKMRGGPLLQHILQRKYFTEEEARRVTKDISLALKFMHDRGIAHRDVKPENVLCTDPNHVSPVKLCDLDLASQRPPQHERHPLSQVASEPDLASPVGSAEFMAPEVVDAYVGDSLKYDKKCDTWSLGVILYIMLAGYAPFQGMCDDEDCGWSEGKPCEDCQQDLFHRIQDGYYEFPEEEWGMISEEAKDLVSNLLKRDPVDRFNADQILSHRWLQQSAASTILQTPSNLINRKDSARDVQQMSEHFNLMNRLADTRLSARFDNKMTMSECGSDLGTATIHGDGSFLSMGGEPFGTFPRKKSVGIAIEKSRSGEFTPPISRASPTTPPPSMLNLSEDLTDSPVKRRSADDSGTFSLFSPASSNGDDSICSPPMVFVDMPSIQLFGTGALLTSVQMTPRHTTEDDASLKSFEDEQENANPIHRIETQVNV
Protein: Chemokine-like protein TAFA-1 (Q7TPG8)
Organism: Mus musculus (Mouse)
Function: Regulatory factor which is ligand for CMKLR2 and is involved in the modulation of neural stem-cell proliferation and differentiation.
Subcellular location: Secreted {ECO:0000269|PubMed:29799787}.
Interaction partners:
Sequence:
MAMVSAMSWALYLWISACAMLLCHGSLQHTFQQHHLHRPEGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSCVDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTRIHPRT
Protein: Zinc fingers and homeoboxes protein 2 (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP) (Zinc finger and homeodomain protein 2) (Q8C0C0)
Organism: Mus musculus (Mouse)
Function: Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA (By similarity). May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells. In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:17056598, ECO:0000269|PubMed:19515908, ECO:0000269|PubMed:30146259}. Note=Colocalizes with EFNB1 intracellular domain in the nucleus. {ECO:0000269|PubMed:19515908}.
Interaction partners:
- GTPase KRas
- GTPase HRas
- GTP-binding protein REM 1
- Midkine
- Dual specificity mitogen-activated protein kinase kinase 1
- Heat shock protein HSP 90-alpha
- Heat shock protein HSP 90-beta
- Rab5 GDP/GTP exchange factor
- Mitogen-activated protein kinase 3
- Serine/threonine-protein kinase B-raf
Sequence:
MASKRKSTTPCMVRTSQVLEQDMLEEADRAKDKGAGMPQSDVTKDSWAAEPEHSSKETEVVEVKSMGENLSKKLQGGYECKYCPYSTQNLNEFTEHVDMQHPNVILNPLYVCAECNFTTKKYDSLSDHNSKFHPGETNFKLKLIKRNNQTVLEQSIEATNHVVPITASGPGSSDNDPGVSVGKTPMTKTGKLKADAKKVPKKPDEAAPENHMEGTARLVTDTAEILARLGSVELLQDSLGHVMPSVQLPPNINLVPKVPVPLNTTKYNSALDTNATMINSFNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKHGISWSPEEVEEARKKMFNGTIQSVPPTITVLPAQLTPTKVSQPILQTALPCQILGQPSLVLTQVTSGSTTVSCSPITLAVAGVTNHGQKRPLVTPQAAPEPKRPHIAQVPEPPPKVANTPLTPASDRKKTKLQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDHRYRCQRGIVHITSESLAKDQMAITGTRHGRTYHVYPDFAPQKFKEKSQGQLKTLEDSFLKSSFPTQAEVERLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMGSGKKGSDAVAPNGALSRLDQLSGAQLAGSLPSPSSAIVQNQEQVHLLRSTFARTQWPTPQEYDQLAAKTGLVRTEIVRWFKENRCLLKTGTLSWLEQYQRHHMSDDRGRDAVSRKVAKQVAESPKNGSEAAHQYAKDPKALSEEDSEKLVPRMKVGGDPTKDCLAGKPSEATSDRSEGSRDGQGSEENEESGIVDFVEVTVGEEDAISEKWGSWSRRVAEGTVERADSDSDSTPAEAGQA
Protein: Putative RING-H2 finger protein ATL62 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase ATL62) (Q9LJL6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- NEP1-interacting protein 2
- At1g71015
- ALA-interacting subunit 1
Sequence:
MNEDALEAVRSRTFFAILTVFYSIFRCCLAYCNKGDDDHLIHPSHSLHVIKATGINPSVLLSIPVVSFNANAFKDNIECVVCLSKFIDEDKARVLPSCNHCFHFDFTDTWLHSDYTCPNCRKNVEEIQNHELSLSPNPNSG
Protein: Interleukin-4 (IL-4) (B-cell stimulatory factor 1) (Lymphocyte stimulatory factor 1) (F1CFE1)
Organism: Sus scrofa (Pig)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|PIRNR:PIRNR001941}.
Interaction partners:
Sequence:
MGLTSQLIPTLVCLLACTSNFVHGHKCDITLQEIIKTLNILTARKNSCMELPVTDVFAAPENTTEKETFCRASTVLRHIYRHHTCMKSLLSGLDRNLSSMANMTCSVHEAKKSTLKDFLERLKTIMKEKYSKC
Protein: Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF) (P18708)
Organism: Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Function: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. Interaction with AMPAR subunit GRIA2 leads to influence GRIA2 membrane cycling.
Subcellular location: Cytoplasm.
Interaction partners:
Sequence:
MAGRSMQAARCPTDELSLSNCAVVSEKDYQSGQHVIVRTSPNHKYIFTLRTHPSVVPGSVAFSLPQRKWAGLSIGQEIEVALYSFDKAKQCIGTMTIEIDFLQKKNIDSNPYDTDKMAAEFIQQFNNQAFSVGQQLVFSFNDKLFGLLVKDIEAMDPSILKGEPASGKRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGASPLDFD