wanglab/gogpt-training-data huggingface dataset:
Protein: FCS-Like Zinc finger 3 (O80506)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins, conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway.
Subcellular location: Nucleus {ECO:0000269|PubMed:24600465, ECO:0000269|PubMed:29945970}. Cytoplasm {ECO:0000269|PubMed:24600465, ECO:0000269|PubMed:29945970}. Note=Shuttles from the cytoplasm to the nucleus when associated with KIN10. {ECO:0000269|PubMed:24600465}.
Interaction partners:
- FCS-Like Zinc finger 16
- FCS-Like Zinc finger 11
- Protein MARD1
- MACPF domain-containing protein CAD1
- Metalloendoproteinase 1-MMP
- Probable protein phosphatase 2C 67
- Protoheme IX farnesyltransferase, mitochondrial
- Metalloendoproteinase 4-MMP
Sequence:
MASYYSGFLGCEEPHFLESCSLCRKHLGLNSDIFMYRGDKAFCSNECREEQIESDEAKERKWKKSSRSLRKNSSETKESAAGNTVRTGTLVVA
Protein: E3 ubiquitin-protein ligase (Q9C803)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MAISKGRLKVWFDKKISEPLIQILRRGAEPKQLAFSAALGITMGVFPICGVTVLLCGVAIASLGSLCHAPTVMLANFIATPIELSLVVPFLRLGEKITGGPHFPLTSDALKKVFTGQASRDVFLSIGNALLGWLIAAPFVIVALYIMFLPCFKILVRKFSSVDSTAKTPTKERIA
Protein: MiRP K channel accessory Subunit (Q9TZ55)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MPDRRLAIVSFHSLFIYSSFDKMSETKKNVLLSLHSLSSLIHVAMFYFLLVQWSKADNPVLTHFQIFCLVIIGIGFLIILILIFSIFKSEMKSDSHARRFFHIWPLVHIALSTAYQLFTQIVISHWKTYQIPILYSSYATTVSVCIHLVLHSMAVFWKV
Protein: Collagen alpha-2(I) chain (Alpha-2 type I collagen) (P02466)
Organism: Rattus norvegicus (Rat)
Function: Type I collagen is a member of group I collagen (fibrillar forming collagen).
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793}.
Interaction partners:
- Collagen alpha-1
- Collagen alpha-1
- Lumican
- Integrin beta-1
- Collagen type V alpha 2 chain
- CD44 antigen
- Integrin alpha-2
- Collagen alpha-1
- Fibrillin-1
- Collagen alpha-1
Sequence:
MLSFVDTRTLLLLAVTSCLATCQSLQMGSVRKGPTGDRGPRGQRGPAGPRGRDGVDGPVGPPGPPGAPGPPGPPGPPGLTGNFAAQYSDKGVSAGPGPMGLMGPRGPPGAVGAPGPQGFQGPAGEPGEPGQTGPAGSRGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAQGVKGEPGAPGENGTPGQAGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGELGPVGNPGPAGPAGPRGEAGLPGLSGPVGPPGNPGANGLTGAKGATGLPGVAGAPGLPGPRGIPGPVGAAGATGPRGLVGEPGPAGSKGETGNKGEPGSAGAQGPPGPSGEEGKRGSPGEPGSAGPAGPPGLRGSPGSRGLPGADGRAGVMGPPGNRGSTGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNVGPAGKEGPVGLPGIDGRPGPIGPAGPRGEAGNIGFPGPKGPSGDPGKPGEKGHPGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPAGPPGFQGLPGPSGTAGEVGKPGERGLPGEFGLPGPAGPRGERGPPGESGAAGPSGPIGIRGPSGAPGPDGNKGEAGAVGAPGSAGASGPGGLPGERGAAGIPGGKGEKGETGLRGEIGNPGRDGARGAPGAIGAPGPAGASGDRGEAGAAGPSGPAGPRGSPGERGEVGPAGPNGFAGPAGSAGQPGAKGEKGTKGPKGENGIVGPTGPVGAAGPSGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGITGPPGPPGAAGKEGIRGPRGDQGPVGRTGEIGASGPPGFAGEKGPSGEPGTTGPPGTAGPQGLLGAPGILGLPGSRGERGQPGIAGALGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGSDGPPGRDGQPGHKGERGYPGNIGPTGAAGAPGPHGSVGPAGKHGNRGEPGPAGSVGPVGAVGPRGPSGPQGIRGDKGEPGDKGARGLPGLKGHNGLQGLPGLAGLHGDQGAPGPVGPAGPRGPAGPSGPIGKDGRSGHPGPVGPAGVRGSQGSQGPAGPPGPPGPPGPPGVSGGGYDFGFEGGFYRADQPRSQPSLRPKDYEVDATLKSLNNQIETLLTPEGSRKNPARTCRDLRLSHPEWKSDYYWIDPNQGCTMDAIKVYCDFSTGETCIQAQPVNTPAKNAYSRAQANKHVWLGETINGGSQFEYNAEGVSSKEMATQLAFMRLLANRASQNITYHCKNSIAYLDEETGRLNKAVILQGSNDVELVAEGNSRFTYTVLVDGCSKKTNEWDKTVIEYKTNKPSRLPFLDIAPLDIGGTNQEFRVEVGPVCFK
Protein: Paired box protein 6 homolog (Homeobox and paired domain-containing protein vab-3) (Protein male abnormal 18) (Variable abnormal morphology protein 3) (G5EDS1)
Organism: Caenorhabditis elegans
Function: Transcription factor that binds a motif with the core sequence 5'-GCGTA-3' in the promoter of various genes. During development, required for cell fate specification probably by promoting or repressing expression of genes involved in specific cell fate. Involved in head epidermal morphogenesis. Involved in gonadal distal tip cell (DTC) migration, during which modulates expression of the integrin alpha genes, pat-2 and ina-1. Regulates ventral and dorsal cephalic sheath (CEPsh) glia differentiation and expression of transcription factor hlh-17 in CEPsh glia. Plays a role in establishing unequal cytokinesis and cell fate specification in male-specific postembryonic blast cell B. May cooperate with the phosphatase eya-1 and transcription factor ceh-32 to regulate the transcription factor ets-5.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|RuleBase:RU000682, ECO:0000269|PubMed:7659159}.; SUBCELLULAR LOCATION: [Isoform b]: Nucleus {ECO:0000269|PubMed:7659160, ECO:0000269|PubMed:9858725}. Cytoplasm {ECO:0000269|PubMed:9858725}. Note=Nuclear localization is temporally and spatially regulated in two sets of neuronal sublineages. {ECO:0000269|PubMed:9858725}.
Interaction partners:
- Mitochondrial import inner membrane translocase subunit tim-22
- Homeobox protein ceh-32
- Protein phosphatase eya-1
- Mitochondrial import inner membrane translocase subunit Tim9
- Protein lin-32
- Protein male abnormal 21
- Mitochondrial import inner membrane translocase subunit Tim10
- Integrin alpha ina-1
- Homeobox protein egl-5
- Helix-loop-helix protein 17
Sequence:
MSDAGHTGVNQLGGVFVNGRPLPDATRQRIVDLAHKGCRPCDISRLLQVSNGCVSKILCRYYESGTIRPRAIGGSKPRVATSDVVEKIEDYKRDQPSIFAWEIRDKLLADNICNNETIPSVSSINRVLRNLAAKKEQVTMQTELYDRIRIVDNFPYNSSWYGQWPIPMNGAVGLNPFVPAPLIEPKTEGEFEKDEDQKPPTEPEDDAAARMRLKRKLQRNRTSFTQVQIESLEKEFERTHYPDVFARERLAQKIQLPEARIQVWFSNRRAKWRREEKMRNKRSSGTMDSSLSNGTPTPTPGSVTGSNMTNPIGSPASTPNRFPSNNSANLPTTNFVPQTSQMYAGLSQPAMDPYSFGIANGFSMAPYPQVTDFQPHHMFQGRSPYDFPYPRMPTNGHGFQQSMSPATTAVGDIPTLSSGMSLPVSAVLNSIDPSLTHSQMHELSDLTQEHYWRPQ
Protein: Keratin-associated protein 19-5 (Q3LI72)
Organism: Homo sapiens (Human)
Function: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Interaction partners:
Sequence:
MNYYGNYYGGLGYGYGGFDDLGYGYGCGCGSFRRLGYGGGYGGYGYGSGFGGYGYRSCRPSCYGGYGFSGFY
Protein: Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form] (P01375)
Organism: Homo sapiens (Human)
Function: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Up-regulates the expression of protein phosphatase 1 (PP1), which dephosphorylates the key 'Ser-418' residue of FOXP3, thereby inactivating FOXP3 and rendering Treg cells functionally defective. Key mediator of cell death in the anticancer action of BCG-stimulated neutrophils in combination with DIABLO/SMAC mimetic in the RT4v6 bladder cancer cell line. Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance (By similarity). Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6.
Subcellular location: Cell membrane {ECO:0000269|PubMed:16829952}; Single-pass type II membrane protein {ECO:0000269|PubMed:16829952}.; SUBCELLULAR LOCATION: [Tumor necrosis factor, membrane form]: Membrane; Single-pass type II membrane protein.; SUBCELLULAR LOCATION: [Tumor necrosis factor, soluble form]: Secreted {ECO:0000269|PubMed:23552949}.; SUBCELLULAR LOCATION: [C-domain 1]: Secreted.; SUBCELLULAR LOCATION: [C-domain 2]: Secreted.
Interaction partners:
- TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
- Nuclear factor NF-kappa-B p105 subunit
- TNF receptor-associated factor 2
- Receptor-interacting serine/threonine-protein kinase 1
- Inhibitor of nuclear factor kappa-B kinase subunit alpha
- Tumor necrosis factor receptor type 1-associated DEATH domain protein
- Inhibitor of nuclear factor kappa-B kinase subunit beta
- Baculoviral IAP repeat-containing protein 2
- Caspase-8
- Mitogen-activated protein kinase kinase kinase 7
Sequence:
MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
Protein: Putative translation initiation factor (Q4QE62)
Organism: Leishmania major
Interaction partners:
- Uncharacterized protein
- Putative eukaryotic translation initiation factor 3 subunit 8
- RRM domain-containing protein
- Eukaryotic translation initiation factor 3 subunit E
- Eukaryotic translation initiation factor 3 subunit I
- CSN8/PSMD8/EIF3K domain-containing protein
- Eukaryotic translation initiation factor 3 subunit 7-like protein
- Translation initiation factor-like protein
- Eukaryotic translation initiation factor 3 subunit L
- Putative elongation initiation factor 2 alpha subunit
Sequence:
MTDVNFGRHILIDGLPNNVTPDKRDLFQRHFSRRIGELLGGEKFSLHLLTDPETALLSGAILSCVTETQAEAALAKLNRFPFTKSAVLTTYRWSSLEEARKDDGPYVPPPTANDDDEEEAELVHNMAEDPDARPQFLIKSGVSFDCDWYWFNWEKNEPDLYRRRKISKDDPLCRWSEVDRDNKKLVSGMVCSALPVSRPLPVWSTYGSMVISQHEKGLRVWAGRSMRLHFEITMDINAFMVSPCEKYIIVQTPKDISIINLRTAKKIRTIGNLDLHSDDLWPIMRFSADDSLVVVCKTGYRPMDSAEVPEGHLNIYVSETMKLLKGRGSSGHSFAIPGLYKAEWNPVVGTQMAYVCELGPNQGWKAVVADMVVNEDGEVEQRVLNERNFLVATRLDMLWHPAGTFLCVRVAAKGPTEYFLFHVAERNVPITRLSIKRGYIPTRFAWQTGGDKFAVLLKRDGVGAGLGETGVLQIFMIGKQGPKVLHEVATSATHLFWAPRGGRLAAANFDKSLLHFFVLHDNNTITDKNKLSGISATNCEWDPTGRYFAVWVSSIHEQTLAPQYRIFDYTGNELFKKAVKPLSHFAWRPLPPTLLTQSDVKKARDMIKTLVRDYEATEMAHKAEEQERIDKERKSKEEDYIKRMKMAARYAEEKGMVQTREEQRANSKWVRYNNNRLKALPDEEHIIHEDVTEYHLVSRRQVGTGVAKK
Protein: ER membrane protein complex subunit 3 (Q9SU27)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- ER membrane protein complex subunit 4
- ER membrane protein complex subunit 6
- ER membrane protein complex subunit 1
- Membrane magnesium transporter
- ER membrane protein complex subunit 2
- ER membrane protein complex subunit 2
- ER membrane protein complex subunit 10
- ER membrane protein complex subunit-like protein
- ER membrane protein complex subunit 7 homolog
- ER membrane protein complex subunit 8/9 homolog
Sequence:
MAEDLVLDTAIRDWVLIPLSVVMVLIGILRYFVSKLMRSTPTPDAKMVKEGQVVIRARNLKVGANFIPPKSFRARRFYFSNEENGLLHVPKGEAQNPQAAMFSDPNMAMDMMKKNLSMIIPQTLTFAWVNFFFSGFVAAKIPFPLTQRFRSMLQNGIDLSTVDVSYVSSRSWYFLNLFGLRGLFSLILGDENAIDDTQRMMQMGGFGFDASKSLGAEKDGLDIIQHEWALPRFEQRAESVLRKLVK
Protein: Cytochrome c oxidase assembly factor 3, mitochondrial (Cytochrome c oxidase protein 25) (Required for respiratory growth protein 10) (Q3E7B2)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Required for assembly of cytochrome c oxidase (complex IV). With COX14, regulates negatively COX1 translation and is involved in MSS51 association with newly synthesized COX1.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16823961, ECO:0000269|PubMed:20876281, ECO:0000269|PubMed:21068384}; Single-pass membrane protein {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16823961, ECO:0000269|PubMed:20876281, ECO:0000269|PubMed:21068384}.
Interaction partners:
- Protein MSS51, mitochondrial
- Cytochrome c oxidase assembly protein COX14
- Cytochrome c oxidase assembly factor 1
- Cytochrome oxidase assembly protein SHY1
- Cytochrome c oxidase subunit 1
- Cytochrome b-c1 complex subunit 1, mitochondrial
- mRNA-binding protein PUF3
Sequence:
MVLNPSKYQDTRTWKMTPAMIRARKPFFKGNMLGLTLLLGVTGSVYYYTYHFLHKDNDFADVPIPPIDPQELEALKKEYEAKKKA
Protein: Isoleucine--tRNA ligase, mitochondrial (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS) (Q8BIJ6)
Organism: Mus musculus (Mouse)
Subcellular location: Mitochondrion matrix {ECO:0000305}.
Interaction partners:
- Bifunctional glutamate/proline--tRNA ligase
- Methionine--tRNA ligase, cytoplasmic
- Methionine--tRNA ligase, mitochondrial
- Probable proline--tRNA ligase, mitochondrial
- Probable arginine--tRNA ligase, mitochondrial
- Leucine--tRNA ligase, cytoplasmic
- Probable leucine--tRNA ligase, mitochondrial
- Lysine--tRNA ligase
- Glutamine--tRNA ligase
- Arginine--tRNA ligase, cytoplasmic
Sequence:
MHWGLCPRGPGAAAVAAAGSFWGPARLPSRLGCLGMTRRLVVRSVAGADSPQSSSKGGRYRDTVLLPQTSFPMKLLGRQQSDMELEIQQKCGFSELYSWQRERKVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRFHMMRGSKVHFVPGWDCHGLPIETKVLSELGVDAQSLSAMEIREKARSFAQAAIEKQKSAFVRWGVMADWNNCYYTFDPKYEAKQLRVFYQMYEKGLVYRSYKPVYWSPSSRTALAEAELEYNPEHVSRSIYVRFPLLRPPPKLESLTDASSPVSVLVWTTQPWTIPANQAICYMPEAKYAVVKCSASGHLYILAEDKIAPVASALETTFDVVAAFSGVDLEGGTCSHPLTPDKVSPLLPATHVTMAKGTGLVHTAPAHGMEDYSVASQHSLPMDCLVDEGGMFTDAAGPELQNKAVLKEGTDVVIKMLQATKNVLKEENIVHSYPCDWRTKTPVLIRASKQWFVNITDIKAAAKESLKTVKFIPGAALNSMTDMLDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQTTEHIIKLVEQHGSDVWWTLPAEQLLPAEVLAQAGGPGALEYAPGQDILDIWFDSGTSWSCVLQDTQQRADLYLEGKDQLGGWFQSSLLTSVATRSKAPFRTVMVHGFTLGEKGEKMSKSLGNVINPDTIISGGKDHSKEPPYGADILRWWIAESNVFTEVTIGPSVLSAARDDISKLRNTLRFLLGNLTGFNPETDSVPVKNMYVIDQYMLHLIQDFATKITDSYKQYDFGKVVRLLKAFYTRELSSFYFSIVKDRLYCENEKDPKRRSCQTALAEILDVLVRAFAPILPHLAEEVFQHIPYVTEPKSVFRTGWINTSSIWKKPGLEEAVESACAMRDSFLGSIPGKNAAEYEVIIVIEPGLLFEIMEMLQAEETSSTSQLNELMMASQTTLLAQEPRERTAGDIELTGTFVINLEGGDIREESSYKVIVVPTAREKCPRCWKHTSETADALCPRCAEVIGAK
Protein: UPF0598 protein C8orf82 homolog (Q8VE95)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MWPPSGAVRNLALVLARSQRARTCSGVERVSYTQGQSPEPRTREYFYYVDHQGQLFLDDSKMKNFITCFKDLQFLVTFFSRLRPNHSGRYEASFPFLSLCGRERNFLRCEDRPVVFTHLLASDSESPRLSYCGGGEALAIPFEPARLLPLAANGRLYHPAPERAGGVGLVRSALAFELSACFEYGPSSPTVPSHVHWQGRRIALTMDLAPLLPAAPPP
Protein: U2 small nuclear ribonucleoprotein A' (U2 snRNP A') (Looks exceptionally like U2A protein 1) (Q08963)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in pre-mRNA splicing. Associates to U2 snRNA in a MSL1 dependent manner and is required for normal accumulation of U2 snRNA. Required for the spliceosome assembly and the efficient addition of U2 snRNP onto the pre-mRNA.
Subcellular location: Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Splicing factor MUD2
- Protein HSH49
- Pre-mRNA-splicing factor CWC2
- Pre-mRNA-splicing factor SNU114
- Protein LUC7
- Pre-mRNA-processing protein 45
- U1 small nuclear ribonucleoprotein A
- Pre-mRNA-splicing factor PRP46
- U1 small nuclear ribonucleoprotein 70 kDa homolog
- Pre-mRNA-splicing factor SNT309
Sequence:
MKFTPSIVIDAPQYYVDHFNGKYNVDKCVILRDLQLETDSESMPSSLKHLTKPTHILDLTNNDLIMIPDLSRRDDIHTLLLGRNNIVEVDGRLLPMNVQNLTLSNNSIRRFEDLQRLRRAPRTLKNLTLIGNQVCHLANYREHVLRLVPHLETLDFQNVTAEERKSAMSFPRQADGDTLGPVNTAIRDNGSRDKTMEIMNLVVSKMTVERRNELKKQLAEATSLEEIARLEKLLSGGV
Protein: Single-strand DNA-binding protein (P0A3W8)
Organism: Rhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium radiobacter)
Function: Involved in DNA transformation; mediates the nuclear uptake of single-stranded DNA copies of the transferred DNA (T-DNA) element. Binds single-stranded but not double-stranded DNA regardless of nucleotide sequence composition.
Subcellular location: Secreted. Host nucleus. Note=In infected cells, it is found in the nucleus.
Interaction partners:
Sequence:
MDLSGNEKSRPWKKANVSSSTISDIQMTNGENLESGSPTRTEVLSPRLDDGSVDSSSSLYSGSEHGNQAEIQKELSALFSNMSLPGNDRRPDEYILVRQTGQDAFTGIAKGNLDHMPTKAEFNACCRLYRDGAGNYYPPPLAFDKISVPAQLEETWGMMEAKERNKLRFQYKLDVWNHAHADMGITGTEIFYQTDKNIKLDRNYKLRPEDRYVQTERYGRREIQKRYQHELQAGSLLPDIMIKTPKNDIHFVYRFAGDNYANKQFSEFEHTVKRRYGGETEIKLKSKSGIMHDSKYLESWERGSADIRFAEFVGENRAHNRQFPTATVNMGQQPDGQGGLTRDRHVSVEFLMQSAPNSPWAQALKKGELWDRVQLLARDGNRYLSPHRLEYSDPEHFTELMNRVGLPASMGRQSHAASIKFEKFDAQAAVIVINGPELRDIHDLSPENLQNVSTKDVIVADRNENGQRTGTYTSVAEYERLQLRLPADAAGVLGEAADKYSRDFVRPEPASRPISDSRRIYESRPRSQSVNSF
Protein: Rhamnulokinase (EC 2.7.1.5) (Rhamnulose kinase) (Q1R415)
Organism: Escherichia coli (strain UTI89 / UPEC)
Function: Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). It could also play a role in the metabolism of some rare sugars such as L-fructose. Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. It can also phosphorylate L-fuculose and L-xylulose. It requires the R-configuration at the C-3 atom.
Interaction partners:
Sequence:
MTFRNCVAVDLGASSGRVMLARYERECRSLTLREIHRFNNGLHSQNGYVTWNVDSLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDQQGQRVGLPVAYRDSRTNGLMAQAQQQLGKRDIYQRSGIQFLPFNTIYQLRALTEQQPELIPHIAHALLIPDYFSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPGNVIGHWICPQGNEIPVVAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTALAANITNEGGAEGRYRVLKNIMGLWLLQRVLQERQINDLPALIAATQALPACRFIINPNDDRFINPDEMCSEIQAACRETAQPIPESDAELARCIFDSLALLYADVLHELAQLRGEDFSQLHIVGGGCQNTLLNQLCADACGIRVIAGPVEASTLGNIGIQLMTLDELNNVDDFRQVVSTTANLTTFTPNPDSEIAHYVAQIHSTRQTKELCA
Protein: Erythrocyte membrane protein 1, PfEMP1 (Q8I2E3)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MALGRPGGEDKYKNAKDAKHLLDSIGEEVYKEIVEKDDAEKYKEALKGKLSQASIWRETVSSLKTCDIIKYEGHKLLAARGDPCKKDTNGNDVDRFSVKEQAEYDNKKMKCSNGSNGSNGKNEGACASFRRLNLCKKNMEKIPTSSTKHDLLADVCMAANYEAQSLIRDHPKYKLKYSDSQLCTELARSFADIGDIVRGRDLYLGNPQEKGKRDELDKKLKDIFKQIHDDVTTNGKNKDALKTRYNDDAKGGHFYQLREDWWIANRHTVWEAITCDDDDKLGGYSYFRATCGSGNNATLARDKCTCNNGDVPTYFDYVPQYLRWFEEWAEDFCRKKKKYVDIVKTYCRGKDKNSEERYCSRNGFDCEKTKRAIGKLRYGKQCISCLYACNPYVEWIDNQRKQFLKQKQKYINVINGAPVSRRQKRDARNENYDGYESKFYKILKIDYQNVEDFLKKLSNEEICTKVQDTEGGKINFENVNSGASGTNVESQGTFYRSKYCQPCPHCGVKMKDGKWETKGEDDKCNIKLYRPKGGKDGTPIKILKSGEKQKEIETKLKAFCKTQNGGGGSDDCGGNSDSSLCEPWQCYQPEELTKDDQGEEDVDDLEYENEVINAGGLCILKKKKEKKTDNDPDEIQKTYNDFFNFWVAHMLKDSIYWKKKLQRCLQNGNRIKCGNQQCNNDCECFQKWIKQKKDEWDRIKQQFRKQDFRKQGENIAGGMLGKEIESPDFVLQEVLKLEFYKEKSEDGSAQDTENSLDEEEAEELKYIREIIEKKNQEPAGANGQKTIMDKLIDYEKDEAKKCKDCQETQPQPPGGDGVAKIGQPRSEVQPEEEEEEEEEEEEEDKEDDDDLDRKDAEDQEAEVETAKEGDVVTTKETTVEDPKVCDIVKTALENRENLQDACNLKYVKGKNYGWKCVPTTSGGDNNTPGETTGSESERAEPTRAKRAAPSSPSGKDTGSVCVPPRRRKLYIHDLQSLIGKDSTTPTQEDLLKWFIETAAIETFFLWHRYKKIKEKEIEEKRKRENGELPFLARSTSVEMKALSGAGGGPELTGSGSDDPNDPNNIYSGKIPPPFLRQMFYTLADYKDILFGDKGEKNGYSDIINGDKEMAQKEQNIKTAIESVFKPSGSSPPAPGKKNPVQTPKDWWTKYGPSIWEGMVCALTYKENSSGGEGKTIEKVKTADDKDLFDTLKGKYSDYEKVKLEDTSGAKPKDPKASPSGEKTTLVDFISRPPYFRYLEEWGQNFCKKRTEMLGKIKEECRGDRGGHQYCSGDGHDCTREDIKHNDMFSNLDCRPCYKQCRKYRKWIDIKFEEFRKQEKKYEEEHGKVITSSNNADDKNIYEKLKDYTSAANFLEALKHCKDGQTGGEKKSNDQDNKINFNDPKTTFGPLEYCKTCPPNKVNCNGRRRTNPCTPDNGKGNKWIEVFDKIPKNNGKTTTIDVHMIDRRGPFIKEYLKNSEKSFKDSYLFKSLRTEEWECRFNKEKKMDVCKLNKFDANIDLNEYTTFKVLIVYWLEDFLYSYYILKKKIELCTQNKEQTCSEGNSKNGCVCVKKWVEKKKKEWDQIKKHFNNREQKEGDDDMKSSVKMFLEDLQHLTELNKIMKPCTELYHFLKSLGCTETDSSENSKEDAIDCMLKKLEKKTESCSDEHSDQTHQTSCDSPPLVEDEDDTLHEEIEVKMPEICKNVVDTKKENDETGETCTSEDTITKETVETDSTDGPKQEEERIAPSAGDDGATRGPQEPSPKADSGDDNPETPQPKPPSNVFDNPHVKTALMSSTIMWSIGIGFAAFTYFYLKKKTKSTIDLLRVINIPKSDYDIPTKLSPNRYIPYTSGKYRGKRYIYLEGDSGTDSGYTDHYSDITSSSESEYEELDINDIYVPGSPKYKTLIEVVLEPSGNNTTASGNNTTASGNNTTASGNNTTASDTQNDIQNDGIPSSKITDNEWNTLKHDFISNMLQSEQPNDIPNDYTSGTIPTNTNITTTSRHNVDNNTNTTMSRDNMEEKPFITSIHDRDLYTGEEYNYDMSTNSGNNDLYNGKNNLYSGQNNVYSGIDPTSDNRGLTSGKHDSYSGIDLINDALSGNQPIDIYDELLKRKENELFGTNHTKKNTSTNSVAKNTNSDPIHNQLELFHKWLDRHRHMCEKWENHHERLAKLKEEWENETHSGNTHTSDSNKTLNTDVSIQIHMDNPKPINQFTNMDTILEDLEKYKEPYYDVQDDIYYDVNDHDASVVDSNAVDVPSKVQIEMDINTKLVKEKYPITDVWDI
Protein: Plexin domain-containing protein 1 (Tumor endothelial marker 7) (Q91ZV7)
Organism: Mus musculus (Mouse)
Function: Plays a critical role in endothelial cell capillary morphogenesis.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cell junction, tight junction {ECO:0000250}. Secreted {ECO:0000250|UniProtKB:Q8IUK5}. Note=Localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells. {ECO:0000250}.
Interaction partners:
Sequence:
MRAQLWLLQLLLLRGAARALSPATPAGHNEGQDSAWTAKRTRQGWSRRPRESPAQVLKPGKTQLSQDLGGGSLAIDTLPDNRTRVVEDNHNYYVSRVYGPGEKQSQDLWVDLAVANRSHVKIHRILSSSHRQASRVVLSFDFPFYGHPLRQITIATGGFIFMGDMLHRMLTATQYVAPLMANFNPGYSDNSTVAYFDNGTVFVVQWDHVYLQDREDRGSFTFQAALHRDGRIVFGYKEIPMAVLDISSAQHPVKAGLSDAFMILNSSPEVPASQRRTIFEYHRVELDSSKITTTSAVEFTPLPTCLQHQSCDTCVSSNLTFNCSWCHVLQRCSSGFDRYRQEWLTYGCAQEAEGKTCEDFQDDSHYSASPDSSFSPFNGDSTTSSSLFIDSLTTEDDTKLNPYAEGDGLPDHSSPKSKGPPVHLGTIVGIVLAVLLVAAIILAGIYISGHPNSNAALFFIERRPHHWPAMKFHNHPNHSTYTEVEPSGHEKEGFVEAEQC
Protein: Bowman-Birk type proteinase inhibitor 2 (LSI-2) (B3EWN6)
Organism: Lathyrus sativus (White vetchling)
Function: Inhibits trypsin (IC(50)=24.3 nM) and, to a lesser extent, alpha-chymotrypsin (IC(50)=0.51 uM).
Interaction partners:
Sequence:
GDDVKSACCDTCLCTKSNPPTCRCVDVGET
Protein: Iron-sulfur cluster assembly 1 homolog, mitochondrial (HESB-like domain-containing protein 2) (Iron-sulfur assembly protein IscA) (Q4QRC6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. Probably involved in the binding of an intermediate of Fe/S cluster assembly.
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q9BUE6}.
Interaction partners:
- Iron-sulfur cluster assembly 2.
- Iron-sulfur cluster assembly factor IBA57, mitochondrial
- Si:ch211-191d15.2
- Cysteine desulfurase
- NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
- Lipoyl synthase, mitochondrial
- Glutaredoxin-related protein 5, mitochondrial
- Iron-sulfur clusters transporter ABCB7, mitochondrial
- Ferredoxin-2, mitochondrial
- Frataxin.
Sequence:
MSASIARATVRAVSRRKILSTRAALTLTPSAVNKVKQLLDNKPEYIGLKVGVRTRGCNGLTYTLDYTKNKEQSDEEVLQDGVRVFIEKKAQLTLLGTEMDFVETKLSSEFVFNNPNIKGTCGCGESFNI
Protein: Protein interacting with Ttk69 and Sin3A, isoform C (Q9VYL7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSLQTKRQHCYLCDLPRMPWAMINDFSEAVCRGCVNYEGADRIEAVLDAARQMKRLHPASKQQRSHENGEVSAAAAAAVVLQQQQQLQVGPVPGQGPGSHRGGGGGGPPGAPPGSGGPGPSGAGSLSSLGNAVAAAAAAAAVHHHHQMPYQMPVPRIGPPLDYPVKLEDAPGGGVRPVRISHMTPHHLPPNATRGGGGAPGGGVPTAGSGGGSLPPALSVNLKRPPSEDVDVDVSQQQQQSGHGLAPDGSAGNSLSAGGGVSGGCPPGIKRSAMDDPSGVGGRPPLTRGESLPAAVSYVPERQLSGLRDKQQPVRAPSFDASTFKAEHMSPASRRNGSSPPSGPLPPRSVHSPNSSGSSSGRRSSGSRHVSSTTVTSSEVGGSNPGQAVVAGGLGGGGGGGPGSNAASGQLGGPSGGSGQLSCTSGGPGGSASSGSGGNGAIGPASMAPNSVAGDGSPAGGNGPSGSNGSGGSVNPGPGSSGSQGGGGGGTPLASGGGSAGSGGLGGAPGSSAASNSAAAAAAAAAQNATLKCTLCQERLEDTHFVQCPSVNHHKFCFPCSRESIKRQNGLGNEVYCPSGDRCPLANSVIPWAFMQGEITTILGEEVKVKKERES
Protein: Uncharacterized protein (Q382C2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MQPMVLPYVDRKPPISKVMDARVLVWRESERMLRNGEGAAECSYAQKLQVLRSQQLADARKYMDTSAAMRSVKPVLATSSVDADDDDEFCRKRSRESEGPSVDEIRRFEGKLGETLALELTLWSLRRGSHGGVRSQRYTTALHALQDTQKLLRKTLQQMEEINALRFLEQQQFLKVNSEKARLLHVRLRNVRALENILRGNGKRRGSTLLATLE
Protein: Recombination enhancement function protein (P35926)
Organism: Escherichia phage P1 (Bacteriophage P1)
Function: Stimulates microhomologous recombination. Enhances the recA-dependent precise excision of an IS1 element inserted within the E.coli galT gene.
Interaction partners:
Sequence:
MKTIEQKIEQCRKWQKAARERAIARQREKLADPVWRESQYQKMRDTLDRRIAKQKERPPASKTRKSAVKIKSRGLKGRTPTAEERRIANALGALPCIACYMHGVISNEVSLHHIAGRTAPGCHKKQLPLCRWHHQHAAPAEVREKYPWLVPVHADGVVGGKKEFTLLNKSEMELLADAYEMANIMH