wanglab/gogpt-training-data huggingface dataset:
Protein: Dual specificity protein kinase KNS1 (EC 2.7.12.1) (P32350)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Nonessential protein kinase.
Interaction partners:
- Serine/threonine-protein kinase SKY1
- DNA polymerase delta catalytic subunit
- DNA-directed RNA polymerase III subunit RPC4
Sequence:
MSQNIQIGTRKRSRANMNNSTTTGPANNTSSNKTFLDNFEETRTNKLLDEMFARQNSFLTDNLRNSLDLNQADNPLRPRQHQHQLFLDNENAIELDEEPRIINTTINNSNNHNSSRVDEDADDDIIFIKEQPIQFSSPLILPSSSSINNNNNIVTSNNPGCGTAATSNSTYITTPKKFKKQRTISLPQLPLSKLSYQSNYFNVPDQTNAIVPRVTQTENELLHLTGSCAKTLEGNKAVNLTIAHSTSPFSNPPAQIASLPQSNLKKQIGSSLRKFTSNGSSESASSNKSNFKTDKDGHYVYQENDIFGSGGRFVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKTELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLYGRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDETHIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSAIFHYEYHPPVISTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVIGESLYPIHENLEHMAMMQRINGTPFPTDIIDKMFYKSKHKLGNSPSDLNSTVIKHFDRKTLSLQWPEKNKRGDTITTEKSMKRVLQSCDRLDIYISKVLKQDYGDSLSINWNLPPEKNWSLINSKLAWKRQTHSSSSSTTDELDKETFLFWYWFIDLLRKMFEFDPTKRITAKDALDHEWFNLGILDDGIATYNNTQG
Protein: Sialic acid-binding Ig-like lectin 7 (Siglec-7) (Adhesion inhibitory receptor molecule 1) (AIRM-1) (CDw328) (D-siglec) (QA79 membrane protein) (p75) (CD antigen CD328) (Q9Y286)
Organism: Homo sapiens (Human)
Function: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- Sialic acid-binding Ig-like lectin 9
- CMRF35-like molecule 6
- Kallikrein-14
- HLA class I histocompatibility antigen, alpha chain E
- Sialoadhesin
Sequence:
MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDPVHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTALTHRPNILIPGTLESGCFQNLTCSVPWACEQGTPPMISWMGTSVSPLHPSTTRSSVLTLIPQPQHHGTSLTCQVTLPGAGVTTNRTIQLNVSYPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLLGAVGGAGATALVFLSFCVIFIVVRSCRKKSARPAADVGDIGMKDANTIRGSASQGNLTESWADDNPRHHGLAAHSSGEEREIQYAPLSFHKGEPQDLSGQEATNNEYSEIKIPK
Protein: Growth-regulating factor 1 (AtGRF1) (Transcription activator GRF1) (O81001)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. microRNA396-GRF1/GRF3 regulatory module acts as a developmental regulator in the reprogramming of root cells during cyst nematode infection, leading to the formation of the syncytium.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU01002}.
Interaction partners:
- GRF1-interacting factor 1
- GRF1-interacting factor 2
- GRF1-interacting factor 3
- Putative B3 domain-containing protein At5g58280
- B3 domain-containing protein REM10
Sequence:
MDLGVRVSGHETVSSPGQTELGSGFSNKQERSGFDGEDCWRSSKLSRTSTDGFSSSPASAKTLSFHQGIPLLRSTTINDPRKGQEHMLSFSSASGKSDVSPYLQYCRNSGYGLGGMMNTSNMHGNLLTGVKGPFSLTQWAELEQQALIYKYITANVPVPSSLLLSLKKSFFPYGSLPPNSFGWGSFHLGFSGGNMDPEPGRCRRTDGKKWRCSRDAVPDQKYCERHINRGRHRSRKPVEGQNGHNTNAAAAASAAAASTAAAVSKAAAGTSAVAMRGSDNNNSLAAAVGTQHHTNNQSTDSLANRVQNSRGASVFPATMNLQSKETHPKQSNNPFEFGLISSDSLLNPSHKQASYATSSKGFGSYLDFGNQAKHAGNHNNVDSWPEELKSDWTQLSMSIPMAPSSPVQDKLALSPLRLSREFDPAIHMGLGVNTEFLDPGKKTNNWIPISWGNNNSMGGPLGEVLNSTTNSPKFGSSPTGVLQKSTFGSLSNSSSASSTIIGDNNNKNGDGKDPLGPTTLMNTSATAPSL
Protein: ER membrane protein complex subunit 5 (C6Y4A7)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P40540}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- ER membrane protein complex subunit 6
- ER membrane protein complex subunit 3
- TPR repeat protein oca3
- ER membrane protein complex subunit 1
- ER membrane protein complex subunit 4
- UPF0620 protein C83.10
Sequence:
MESSTINAKKISVLLTLFSIIGYTAYSAHESILEIRQDGKLPLDIKCEVILVTLLFTFTTVIIASPLRSIQLNKWSHQRSDLAFLNSRTNFLRIKELKEKIEKVKN
Protein: DEAD-box ATP-dependent RNA helicase 15 (EC 3.6.4.13) (API5-interacting protein 1) (Q5JK84)
Organism: Oryza sativa subsp. japonica (Rice)
Function: ATP-binding RNA helicase involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus (By similarity). Required for tapetal programmed cell death (PCD) and degeneration during anther development. Forms dimer with AIP1 and binds the promoter region of the cysteine protease CP1. Can complement the yeast RNA helicase SUB2. Plants silencing AIP1 and AIP2 are male sterile.
Subcellular location: Nucleus {ECO:0000269|PubMed:21467577}.
Interaction partners:
- Expressed protein
- Os06g0256200 protein
- THO complex subunit 2
- Os02g0767100 protein
- Os11g0100200 protein
- Os12g0100100 protein
- Os08g0427900 protein
- Os07g0237100 protein
- Os09g0363600 protein
- RNA-binding protein Y14B
Sequence:
MGEAEVKDNEVYEEDLVDYEEEVENGADGGAAAANASADVVKKGYVGIHSSGFRDFLLKPELLRAIQDCGFEHPSEVQHECIPQAILGMDVICQAKSGMGKTAVFVLSSLQQIDPVAGQVGALVLCHTRELAYQICHEFERFSKYLPEVKVAVFYGGVHIKKHKDLLKNDCPHIVVGTPGRILALAREKDLSLKNVRHFILDECDKMLDSLDMRRDVQEIFKMTPHDKQVMMFSATLSKEIRPVCKKFMQDPMEIYVDDEAKLTLHGLVQHYIKLSEAEKNRKLNDLLDALDFNQVVIFVKSVSRAAELNKLLCECNFPAISIHSGMTQEERLTRYKNFKEGHKRILVATDLVGRGIDIERVNIVINYDMPDSADSYLHRVGRAGRFGTKGLAITFVSSASDSDVLNQVQERFEVDIKELPEQIDTSTYMPS
Protein: Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Q9UUD6)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
- SAGA complex subunit Sus1
- Ubiquitin carboxyl-terminal hydrolase 14
- SAGA complex subunit Sgf29
- SAGA complex subunit Sgf73
- SAGA complex/transcription factor TFIID complex subunit Taf10
- Probable ubiquitin carboxyl-terminal hydrolase 1
- Probable ubiquitin carboxyl-terminal hydrolase 12
- SAGA complex/transcription factor TFIID complex subunit Taf9
- SAGA complex subunit Ada2
- SAGA complex/transcription factor TFIID complex subunit Taf6
Sequence:
MSTTPLSISRAKKYKTVFKGAAILTTFAALYIVTSPSTGKRLVKNASIKGLYNVSGNDCFLNCVLQSLASQESLLEILKLRCSSSTLYATLYELLQKLNSGPGNPITPGSFLNSLEIATNKKLVRSIQQDAQEFLQHLVETLELQKPHTYKWSKVLSFPVDSPFIGTMEQKVQCCQCLAISISYSTATSIQLCLPPEYSGNSNVSLLSLMEADREQHISDYKCDSCFKSSPKHSKTSCIRTVDWKNPPTILQIQLERTSYTCQGLTRNNVSISFPSKLILKNKHHYILRSLITHSGSVTYGHYLCYRLQDDIWWKANDSLITKSSLNEALSQTRSACLLFYEMESPLALD
Protein: Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG (EC 3.2.2.n1) (Protein LONELY GUY) (Q5ZC82)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Cytokinin-activating enzyme working in the direct activation pathway. Controls the shoot meristem activity. Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms. Reacts specifically with cytokinin nucleoside 5'-monophosphates, but not with di- or triphosphate.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17287810}.
Interaction partners:
- Nitrate reductase
- Nitrate reductase
- Nitrate reductase 1
- protein-serine/threonine phosphatase
- Os04g0589400 protein
- Small ribosomal subunit protein uS2c
- Os01g0220300 protein
- Os06g0255200 protein
- Os02g0102400 protein
- Small ribosomal subunit protein mS29
Sequence:
MAMEAAAERSAGAGAAATAAPESGGGGAGERRSRFRRICVYCGSAKGRKASYQDAAVELGKELVERGIDLVYGGGSIGLMGLVSHAVHDGGRHVIGVIPKSLMPREVTGEPVGEVRAVSGMHERKAEMARFADAFIALPGGYGTLEELLEVITWAQLGIHKKPVGLLNVDGFYDPFLSFIDMAVSEGFIAEDARRIIISAPTARELVLKLEEYVPEYEVGLVWDDQMPHSFAPDLETRITSS
Protein: Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (Cytochrome c oxidase polypeptide IV) (Cytochrome c oxidase subunit IV isoform 1) (COX IV-1) (P19783)
Organism: Mus musculus (Mouse)
Function: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:34616041, ECO:0000269|PubMed:37195149, ECO:0000269|PubMed:38575788}; Single-pass membrane protein {ECO:0000269|PubMed:34616041, ECO:0000269|PubMed:38575788}.
Interaction partners:
- Cytochrome b-c1 complex subunit 1, mitochondrial
- Cytochrome c1, heme protein, mitochondrial
- Cytochrome c oxidase subunit 6B1
- Cytochrome c oxidase subunit 6C
- Cytochrome c oxidase subunit 1
- Cytochrome c oxidase subunit 7C, mitochondrial
- Cytochrome b-c1 complex subunit 2, mitochondrial
- Cytochrome c oxidase subunit 5A, mitochondrial
- Cytochrome c oxidase subunit 2
- Cytochrome c oxidase subunit 5B, mitochondrial
Sequence:
MLASRALSLIGKRAISTSVCLRAHGSVVKSEDYAFPTYADRRDYPLPDVAHVTMLSASQKALKEKEKADWSSLSRDEKVQLYRIQFNESFAEMNRGTNEWKTVVGMAMFFIGFTALVLIWEKSYVYGPIPHTFDRDWVAMQTKRMLDMKANPIQGFSAKWDYDKNEWKK
Protein: Protease inhibitor HPI (HbPI1) (Protease inhibitor 1) (Q6XNP7)
Organism: Hevea brasiliensis (Para rubber tree) (Siphonia brasiliensis)
Function: Inhibitor of serine proteases, strongly inhibits subtilisin A and weakly inhibits trypsin. Does not inhibit chymotrypsin, papain, pepsin, pronase E, protease type XIII and thermolysin. HPI-1 inhibits subtilisin A with an Ki of 0.21 nM. HPI-2a inhibits subtilisin A with an Ki of 0.08 nM. HPI-2b inhibits subtilisin A with an Ki of 0.1 nM.
Interaction partners:
Sequence:
MASQCPVKNSWPELVGTNGDIAAGIIQTENANVKAIVVKEGLPITQDLNFNRVRVFVDENRVVTQVPAIG
Protein: Roundabout guidance receptor 1 (A0A0A0MSX4)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEGNAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSPEDQVSLAQQISDVVKQPAFIAGIGAACWIILMVFSIWLYRHRKKRNGLTSTYAGIRKVPSFTFTPTVTYQRGGEAVSSGGRPGLLNISEPAAQPWLADTWPNTGNNHNDCSISCCTAGNGNSDSNLTTYSRPADCIANYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPSGQPTPYATTQLIQSNLSNNMNNGSGDSGEKHWKPLGQQKQEVAPVQYNIVEQNKLNKDYRANDTVPPTIPYNQSYDQNTGGSYNSSDRGSSTSGNQGHKKGARTPKVPKQGGMNWADLLPPPPAHPPPHSNSEEYNISVDESYDQEMPCPVPPARMYLQQDELEEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEETGHMQHQPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMDTDAPEEEEDEADMEVAKMQTRRLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEEDNISSGRSSVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQDAAGRRHFHASQCPRPTSPVSTDSNMSAAVMQKTRPAKKLKHQPGHLRRETYTDDLPPPPVPPPAIKSPTAQSKTQLEVRPVVVPKLPSMDARTDRSSDRKGSSYKGREVLDGRQVVDMRTNPGDPREAQEQQNDGKGRGNKAAKRDLPPAKTHLIQEDILPYCRPTFPTSNNPRDPSSSSSMSSRGSGSRQREQANVGRRNIAEMQVLGGYERGEDNNEELEETES
Protein: Small ribosomal subunit protein eS1 (E9PFI5)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03122}. Nucleus {ECO:0000256|HAMAP-Rule:MF_03122}. Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. {ECO:0000256|HAMAP-Rule:MF_03122}.
Interaction partners:
Sequence:
MAVGKNKRLTKGGKKGAKKKVVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLQHWKRHRKGLPIYLSSP
Protein: FI05392p (LD01189p) (WD repeat domain 62, isoform A) (WD repeat domain 62, isoform E) (Q9VQ54)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDAPDVGRIIRAPARRKRNDEQLMDRIKLKKVLGLTVCSNAALDVSPVSGLLAYPAGCTVVLFNAKRQTQAYLVNTSRKAFTSVAFSRCGRYVATGECGINPAIKVWELETPNGSLEHCSGGSVVAEFVDHKYAVTCVAFSPTGKYLVSVGSQHDMIVNVFDWRANLKMASNKISSKVAAVCFSEDGSYFVTVGNRHVKYWYLEGGRKYKDPIPLMGRSAILGDLRDNDFCAVACGKGICAESTYAITRQGHLVEFSSRRLLDKWVQCRTTNANCICVNERFILVGCAESIIRIFNSATLEYVTTLPRTHYLGVDVAQGIQINHIMSVPQQAKFPDCIAMVFDEQRSKVSCVYNDHSLYIWDLRDISRVGKSHSFLYHSTCIWGVETVPYNVEREPSQTLPEECFVTCSSDDTIRVWGLDGCTNNDIYRRNIYSKELLKIVYSDDELQFIKDQGSSLFDKAGNSSYDGRNGVRCIKISPELQHLASGDRCGNIRVYSLVNLRLLTTIEAHESEVLCLEYSNEKIERKLLASASRDRLIHVFDVAQNYLLLQTLDDHSSSITSIKFVGAGLNFQMISCGADKSIMFRSFQGNIFMRGTNTSGKTTLYDMEVDSNAKHILTACQDRNVRVYGTQNAKQTKTFKGSHSDEGSLIKLSLDPSGIYVATSCTDKTLAVYDYYSNECMARMYGHSELVTGLKFTNDCRHLISASGDGCIFIWQVPHDMIVTMQARMSQQRLRSGHAPLPRPLAPISPPDGIVLESPTSEIEQPQLQPKFGVAERFSDVGQLPQWAMRKAAADSDSGALSIPTPSGGSATVPGMHAASSMGNLSSSPSQQMTGLAPRARGRWAQRSTQLETADDLRSNSESPLGTVSSVGGHSGVNVQTSDYNSASSKDITYNQTYLSEDSSIDSGMETRRGELKFIGSSNNGTVVTVSSVSSIAVSASNGAMSTGSGAAQQRLQLPDKRLKPGLRFDTHTHDHDGDVEDISDGERTSSDHGMFYNNLAPSTPTDFKVTAMNEDELRKSVRRQKFEKSGLQLTPSALSGNGSSHTASTGTGTSDTEDEGSTPSAENAERSLASTLGGSSENLPQSSTNSFLHAALPEGPGLTTPMERGGSSRRSISAKHNTENGKSVAAPPTITKSYTSTKKEELLQVINKVKQQLENVGHRPLRGSHSISDLSLAANLDGSRNAGGGPGRYQKPGNPKTLNPMPIEESSIRRACSLSDLHMGNFGKPGKSQNGTPQKPQVQHRNGNVSRSASKRNSLQGKTGLGASSNSMNVLNQGSDSEPEDSNRLRSASNGQGRSNGPIAANRQYSNKINNVNNNRRKTPNFSSATPMQDDSSSEETPNSTVNNKPIVPPRPRNLAFDHKSKLMINNSGSPGGNAKQRSGVTSTEDFEGTDPEAQVHNVINKLYTTTQAAMQLHANLKNTLLLKELENALIMSRNMLSSITNRQADKTNNGGGGLGVGGSGGLNHDQLNADNGDYLMMVNNCADLLSNLRTKHKPDDCENNS
Protein: Serine/arginine-rich splicing factor RSZ22A (RS-containing zinc finger protein 22A) (At-RSZ22a) (At-RSZp22a) (AtRSZ22a) (Q9SJA6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probably involved in intron recognition and spliceosome assembly.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:O81126}.
Interaction partners:
- Serine/arginine-rich splicing factor SC35
- RNA-binding protein Y14
- Serine/arginine-rich splicing factor RS31
- Serine/arginine-rich splicing factor RS40
- Serine/arginine-rich splicing factor RS31A
- Serine/arginine-rich SC35-like splicing factor SCL30A
- RBR-type E3 ubiquitin transferase
- RNA-binding protein 48
- P-loop nucleoside triphosphate hydrolase superfamily protein
- TRAF-like family protein
Sequence:
MSRVYVGNLDPRVTERELEDEFRSFGVIRSVWVARRPPGYAFLDFEDSRDARDAIREVDGKNGWRVEQSHNRGGGGGRGGGRGGGDGGRGRGGSDLKCYECGESGHFARECRSRGGSGGRRRSRSRSRSPPRYRKSPTYGGRRSYSPRARSPPPPRRRSPSPRGRNYSRSPPPYRARDEVPYANGNGLKDVRRSRS
Protein: Vacuolar membrane protease (FXNA-related family protease 1) (Q0WVZ7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Vacuole membrane {ECO:0000256|ARBA:ARBA00004128}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004128}.
Interaction partners:
- Protein ACCELERATED CELL DEATH 6
Sequence:
MRKRHPKASDLTEPSSSSKETDASSDKDALDKEVQADVKRSGKVWLSVLILITYSSWFVYNYQLGNLPKPLTAKQAGKRGFSEIEAIKHVKALTQFGPHPVSSDALVHALEYVLAEVEKVKETAHWEVDVNVDFFESKFGVNRLVGGLFKGKSLVYSDISHIVLRILPKYESDAGDNAILVSSHIDTVFTTGGAGDCSSCVAVMLELARSASQSAHGFKNSIIFLFNTGEEEGLNGAHSFITQHPWSSTVRLAIDLEAMGTGGKSSIFQAGPSPWAIENFALAAKYPSGQIIGQDLFTSGIIKSATDFQVYKEVAGLSGLDFAFADNTAVYHTKNDKIELIKPGSLQHLGENMLAFLLRVASSSDLPKDKTLQGEERSNPDSAVYFDVLGKYMIVYRQSLATMLYVSVIMQSILIWVLSVFMGGYPAVVSLILSCLSIILSWIFSVAFSVAVAFILPWISSSPVPFASNPWMVVGLFVSPAILGSISGQHVAFIFLRKKSSNRNSNKMQVSPRLRDNLARLEAERWLFKSGFIQWLVLLALGTYYKLGSTYLALVWLVPPAFAYGLLEATLSPIRLPKPLKLATLLISLAVPILVSSGSFIQLTGTMIGMLIRFDSNPGVTPEWLGSALIAVAIATFISLSMVYLLAYIHLSGAKKSIVTALCIITALSLALVSSGVLPAFTEDTARAVNVVHVVDTSGQDQVAFISLFSNTPGNLNMEAEQIKEGFRCGRENKIDFVSFEAKYNCVTKKDAEVGWDKHDIPVLRVINDKEREGGRVIAVSMDTGGSSRWTLRIDMDEIEDFTMQVGEEEEEELMIERGEKSSNEEGWHQIQFAGGKKAPTSFVLKLYKEEEVSDDKKKQRPLLKLRTDLNRRTPQVQRVLERLPPFCTMFGKSTSPFTLAFLASLPYTK
Protein: Bowman-Birk type proteinase inhibitor 2a (LSI-2a) (P86932)
Organism: Lathyrus sativus (White vetchling)
Function: Inhibits trypsin (IC(50)=0.9 nM) and alpha-chymotrypsin (IC(50)=1.1 nM).
Interaction partners:
Sequence:
GDDVKSACCDTCLCTKSNPPTCRCVDVGETCHSACLSCICAYSYPPKCQCFDTQKFCYRACHNSEKEEVIKG
Protein: L-asparagine permease 2 (L-asparagine transport protein 2) (P9WQM7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Dual function in both nitrogen assimilation and in protection against acid stress during infection. Involved in asparagine uptake.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- L-asparaginase
- Probable conserved membrane protein
Sequence:
MPPLDITDERLTREDTGYHKGLHSRQLQMIALGGAIGTGLFLGAGGRLASAGPGLFLVYGICGIFVFLILRALGELVLHRPSSGSFVSYAREFYGEKVAFVAGWMYFLNWAMTGIVDTTAIAHYCHYWRAFQPIPQWTLALIALLVVLSMNLISVRLFGELEFWASLIKVIALVTFLIVGTVFLAGRYKIDGQETGVSLWSSHGGIVPTGLLPIVLVTSGVVFAYAAIELVGIAAGETAEPAKIMPRAINSVVLRIACFYVGSTVLLALLLPYTAYKEHVSPFVTFFSKIGIDAAGSVMNLVVLTAALSSLNAGLYSTGRILRSMAINGSGPRFTAPMSKTGVPYGGILLTAGIGLLGIILNAIKPSQAFEIVLHIAATGVIAAWATIVACQLRLHRMANAGQLQRPKFRMPLSPFSGYLTLAFLAGVLILMYFDEQHGPWMIAATVIGVPALIGGWYLVRNRVTAVAHHAIDHTKSVAVVHSADPI
Protein: Small ribosomal subunit protein uS2m (37S ribosomal protein mrp4, mitochondrial) (O13970)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein bS6m
- Small ribosomal subunit protein uS11m
- Small ribosomal subunit protein uS10m
- Small ribosomal subunit protein uS12m
- Small ribosomal subunit protein uS14m
- Small ribosomal subunit protein bS18m
- Small ribosomal subunit protein uS17m
- Small ribosomal subunit protein uS7m
Sequence:
MLSRKLSPEQLVARRLKIRDWNHKIGAVVAPHYSPTLSIRNPAPPSQLSLPLLLSSGAHLGHSTSIWNPYTQPFIYGKREGIHIISLDQTMVYLRRAISVVRSIAKENGIILFIGTRNGQKDSVVAAAKRARGYHIFDRWLPGLLTNAREVQGKLGGSILCKDNRGKLIQTDKKPSYVFPDLMVILNPLENKSACLEAQKTHVPTIGIIDTDADPRMVTYPIPANDDSLRCTDLIAGLLSRVAEQEYQKANQAFEKDKFTLPL
Protein: Taste receptor type 2 member 16 (T2R16) (Candidate taste receptor mt2r40) (T2R18) (P59529)
Organism: Mus musculus (Mouse)
Function: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5 (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9NYV7}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Taste receptor type 1 member 1
- Taste receptor type 1 member 3
- Taste receptor type 2 member 110
- Guanine nucleotide-binding protein G
- Taste receptor type 2 member 38
- Taste receptor type 2
Sequence:
MVPTQVTIFSIIMYVLESLVIIVQSCTTVAVLFREWMHFQRLSPVETILISLGISHFCLQWTSMLYNFGTYSRPVLLFWKVSVVWEFMNILTFWLTSWLAVLYCVKVSSFTHPIFLWLRMKILKLVLWLILGALIASCLSIIPSVVKYHIQMELVTLDNLPKNNSLILRLQQFEWYFSNPLKMIGFGIPFFVFLASIILLTVSLVQHWVQMKHYSSSNSSLKAQFTVLKSLATFFTFFTSYFLTIVISFIGTVFDKKSWFWVCEAVIYGLVCIHFTSLMMSNPALKKALKLQFWSPEPS
Protein: Alpha-1D adrenergic receptor (Alpha-1A adrenergic receptor) (Alpha-1D adrenoreceptor) (Alpha-1D adrenoceptor) (Alpha-adrenergic receptor 1a) (P25100)
Organism: Homo sapiens (Human)
Function: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Interaction partners:
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit alpha-11
- Guanine nucleotide-binding protein subunit alpha-13
- Guanine nucleotide-binding protein subunit alpha-12
- Alpha-1B adrenergic receptor
- Alpha-1A adrenergic receptor
- Beta-2-syntrophin
- Beta-1-syntrophin
- Utrophin
- Thromboxane A2 receptor
Sequence:
MTFRDLLSVSFEGPRPDSSAGGSSAGGGGGSAGGAAPSEGPAVGGVPGGAGGGGGVVGAGSGEDNRSSAGEPGSAGAGGDVNGTAAVGGLVVSAQGVGVGVFLAAFILMAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWVVALVVSVGPLLGWKEPVPPDERFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGADGAHGMRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRRRRPLWRVYGHHWRASTSGLRQDCAPSSGDAPPGAPLALTALPDPDPEPPGTPEMQAPVASRRKPPSAFREWRLLGPFRRPTTQLRAKVSSLSHKIRAGGAQRAEAACAQRSEVEAVSLGVPHEVAEGATCQAYELADYSNLRETDI
Protein: Serotonin N-acetyltransferase (Serotonin acetylase) (EC 2.3.1.87) (Aralkylamine N-acetyltransferase) (AA-NAT) (P79774)
Organism: Gallus gallus (Chicken)
Function: Catalyzes the N-acetylation of serotonin into N-acetylserotonin.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q16613}.
Interaction partners:
- Acetylserotonin O-methyltransferase
- Aromatic-L-amino-acid decarboxylase
- Amine oxidase.
- Amine oxidase
- Uncharacterized protein.
- Basic helix-loop-helix ARNT-like protein 1
- Establishment of sister chromatid cohesion N-acetyltransferase 1.
- Establishment of sister chromatid cohesion N-acetyltransferase 2.
- DNA-directed RNA polymerase subunit
- G_PROTEIN_RECEP_F1_2 domain-containing protein.
Sequence:
MPVLGAVPFLKPTPLQGPRNSPGRQRRHTLPASEFRCLSPEDAVSVFEIEREAFISVSGDCPLHLDEIRHFLTLCPELSLGWFEEGRLVAFIIGSLWDQDRLSQAALTLHNPRGTAVHIHVLAVHRTFRQQGKGSILMWRYLQYLRCLPCARRAVLMCEDFLVPFYEKCGFVAVGPCQVTVGTLAFTEMQHEVRGHAFMRRNSGC