wanglab/gogpt-training-data huggingface dataset:
Protein: E3 ubiquitin-protein ligase JMJ24 (EC 2.3.2.27) (Inactive histone demethylase JMJ24) (Jumonji domain-containing protein 24) (AtJMJ24) (Protein JUMONJI 24) (F4HZD1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds histone H3 but seems to have lost demethylase activity probably due to its inability to bind iron Fe(2+). Possesses E3 ubiquitin ligase activity and targets directly CMT3 for proteasomal degradation to initiate destabilization of the heterochromatic state (e.g. CHG cytosine methylation and H3K9me2) of endogenous silenced loci. Required for the removal of repressive H3K9me2 histone marks to facilitate the transcription of AtSN1, AtMu1c, solo LTR and SDC, thus counteracting their transcriptional silencing. Mainly required to promote the basal level transcription of silenced loci such as TE and repeats targeted by RNA-dependent DNA methylation (RdDM) for silencing, a specialized branch of the RNA interference (RNAi) pathway. Cooperates also with RNAi pathways for gene silencing both by contributing to the production of 24-nt siRNA to initiate RdDM and by recruiting RDR2 to enable local transcripts to make dsRNA. Antagonizes histone H3K9 demethylase IBM1/JMJ25 function.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768, ECO:0000269|PubMed:26119694, ECO:0000269|PubMed:26979329}.
Interaction partners:
- Histone-lysine N-methyltransferase ATX4
- DNA-binding protein-like
- Lysine-specific demethylase JMJ28
- Lysine-specific demethylase JMJ26
- Histone-lysine N-methyltransferase ATX3
- Histone-lysine N-methyltransferase ATX2
- Histone-lysine N-methyltransferase ATX5
- Histone H3-lysine
- Methyl-CpG-binding domain-containing protein 9
- Ubiquitin carboxyl-terminal hydrolase 2
Sequence:
MQVNFDETCDSVIRMNANEQTRSANGIGNGNGESIPGIPDDLRCKRSDGKQWRCTAMSMADKTVCEKHYIQAKKRAANSAFRANQKKAKRRSSLGETDTYSEGKMDDFELPVTSIDHYNNGLASASKSNGRLEKRHNKSLMRYSPETPMMRSFSPRVAVDLNDDLGRDVVMFEEGYRSYRTPPSVAVMDPTRNRSHQSTSPMEYSAASTDVSAESLGEICHQCQRKDRERIISCLKCNQRAFCHNCLSARYSEISLEEVEKVCPACRGLCDCKSCLRSDNTIKVRIREIPVLDKLQYLYRLLSAVLPVIKQIHLEQCMEVELEKRLREVEIDLVRARLKADEQMCCNVCRIPVVDYYRHCPNCSYDLCLRCCQDLREESSVTISGTNQNVQDRKGAPKLKLNFSYKFPEWEANGDGSIPCPPKEYGGCGSHSLNLARIFKMNWVAKLVKNAEEIVSGCKLSDLLNPDMCDSRFCKFAEREESGDNYVYSPSLETIKTDGVAKFEQQWAEGRLVTVKMVLDDSSCSRWDPETIWRDIDELSDEKLREHDPFLKAINCLDGLEVDVRLGEFTRAYKDGKNQETGLPLLWKLKDWPSPSASEEFIFYQRPEFIRSFPFLEYIHPRLGLLNVAAKLPHYSLQNDSGPKIYVSCGTYQEISAGDSLTGIHYNMRDMVYLLVHTSEETTFERVRKTKPVPEEPDQKMSENESLLSPEQKLRDGELHDLSLGEASMEKNEPELALTVNPENLTENGDNMESSCTSSCAGGAQWDVFRRQDVPKLSGYLQRTFQKPDNIQTDFVSRPLYEGLFLNEHHKRQLRDEFGVEPWTFEQHRGEAIFIPAGCPFQITNLQSNIQVALDFLCPESVGESARLAEEIRCLPNDHEAKLQILEIGKISLYAASSAIKEVQKLVLDPKFGAELGFEDSNLTKAVSHNLDEATKRPQQNSCT
Protein: Killer cell lectin-like receptor subfamily G member 1 (Mast cell function-associated antigen) (Q64335)
Organism: Rattus norvegicus (Rat)
Function: Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells (By similarity).
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Interaction partners:
- Cadherin-1
- T-cell surface glycoprotein CD4
- CD27 antigen
- Granzyme B
- L-selectin
- Cadherin-2
- Interferon gamma
- CD19 molecule
- Inducible T-cell costimulator
- Interleukin-7 receptor subunit alpha
Sequence:
MADNSIYSTLELPAAPRVQDDSRWKVKAVLHRPCVSYLVMVALGLLTVILMSLLLYQRTLCCGSKGFMCSQCSRCPNLWMRNGSHCYYFSMEKRDWNSSLKFCADKGSHLLTFPDNQGVNLFQEYVGEDFYWIGLRDIDGWRWEDGPALSLSILSNSVVQKCGTIHRCGLHASSCEVALQWICEKVLP
Protein: Outer membrane protein assembly factor BamC (P0A903)
Organism: Escherichia coli (strain K12)
Function: Part of the outer membrane protein assembly complex (Bam), which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex that stabilizes the interaction between the essential proteins BamA and BamD. Efficient substrate folding and insertion into the outer membrane requires all 5 subunits. A lateral gate may open between the first and last strands of the BamA beta-barrel that allows substrate to insert into the outer membrane; comparison of the structures of complete and nearly complete Bam complexes show there is considerable movement of all 5 proteins.
Subcellular location: Cell outer membrane {ECO:0000255|HAMAP-Rule:MF_00924, ECO:0000269|PubMed:16079137, ECO:0000269|PubMed:26900875, ECO:0000269|PubMed:26901871}; Lipid-anchor {ECO:0000255|HAMAP-Rule:MF_00924, ECO:0000269|PubMed:16079137, ECO:0000269|PubMed:27686148}.
Interaction partners:
- Outer membrane protein assembly factor BamD
- Outer membrane protein assembly factor BamE
- Outer membrane protein assembly factor BamB
- Outer membrane protein assembly factor BamA
- 4-hydroxy-tetrahydrodipicolinate synthase
- LPS-assembly protein LptD
- LPS-assembly lipoprotein LptE
- Chaperone protein Skp
- Chaperone SurA
- Phospholipase A1
Sequence:
MAYSVQKSRLAKVAGVSLVLLLAACSSDSRYKRQVSGDEAYLEAAPLAELHAPAGMILPVTSGDYAIPVTNGSGAVGKALDIRPPAQPLALVSGARTQFTGDTASLLVENGRGNTLWPQVVSVLQAKNYTITQRDDAGQTLTTDWVQWNRLDEDEQYRGRYQISVKPQGYQQAVTVKLLNLEQAGKPVADAASMQRYSTEMMNVISAGLDKSATDAANAAQNRASTTMDVQSAADDTGLPMLVVRGPFNVVWQRLPAALEKVGMKVTDSTRSQGNMAVTYKPLSDSDWQELGASDPGLASGDYKLQVGDLDNRSSLQFIDPKGHTLTQSQNDALVAVFQAAFSK
Protein: Dystrobrevin, alpha (A0A8I5ZKV1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MIEDSGKRGNTMAERRQLFAEMRAQDLDRIRLSTYRTACKLRFVQKKCNLHLVDIWNVIEALRENALNNLDPNIELNVARLEAVLSTMFYQLNKRMPSTHQIHVEQSISLLLNFLLAAFDPEGHGKISVFAVKMALATLCGGKIMDKLRYIFSMISDSSGVMVYGRYDQFLREVLKLPTAVFEGPSFGYTEQSARSCFSQQKKVTLNGFLDTLMSDPPPQCLVWLPLLHRLANVENVFHPVECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHAGGSHSNQHQMKEYTSWKSPAKKLTNALSKSLSCASSREPLHPMFPDQPEKPLNLAHIVDTWPPRPVTSMNDTLFSHSVPSSGSPFITRSMLESSNRLDEEHRLIARYAARLAAESSSSQPTQQRSAPDVSFTIDANKQQRQLIAELENKNREILQEIQRLRVEHEQASQPTPEKAQQNPTLLAELRLLRQRKDELEQRMSALQESRRELMVQLEGLMKLLKEEELKQGVSYVPYCRS
Protein: DDB1 and CUL4 associated factor 8 (Q5TAQ8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSSKGSSTDGRTDLANGSLSSSPEEMSGAEEGRETSSGIEVEASDLSLSLTGDDGGPNRTSTESRGTDTESSGEDKDSDSMEDTGHYSINDENRVHDRSEEEEEEEEEEEEEQPRRRVQRKRANRDQDSSDDERALEDWVSSETSALPRPRWQALPALRERELGSSARFVYEACGARVFVQRFRLQHGLEGHTGCVNTLHFNQRGTWLASGS
Protein: Hydroxysteroid 17-beta dehydrogenase 4 (E7ET17)
Organism: Homo sapiens (Human)
Subcellular location: Peroxisome {ECO:0000256|ARBA:ARBA00004275}.
Interaction partners:
Sequence:
MKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRQKNHPMTPEAVKANWKKICDFENASKPQSIQESTGSIIEVLSKIDSEGGVSANHTSRATSTATSGFAGAIGQKLPPFSYAYTELEAIMYALGVGASIKDPKDLKFIYEGSSDFSCLPTFGVIIGQKSMMGGGLAEIPGLSINFAKVLHGEQYLELYKPLPRAGKLKCEAVVADVLDKGSGVVIIMDVYSYSEKELICHNQFSLFLVGSGGFGGKRTSDKVKVAVAIPNRPPDAVLTDTTSLNQAALYRLSGDWNPLHIDPNFASLAGFDKPILHGLCTFGFSARRVLQQFADNDVSRFKAIKARFAKPVYPGQTLQTEMWKEGNRIHFQTKVQETGDIVISNAYVDLAPTSGTSAKTPSEGGKLQSTFVFEEIGRRLKDIGPEVVKKVNAVFEWHITKGGNIGAKWTIDLKSGSGKVYQGPAKGAADTTIILSDEDFMEVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
Protein: Vomeronasal type-1 receptor (A5H1X0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU364061}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU364061}.
Interaction partners:
Sequence:
MIAEAVIRGLLFLSLVLVGVPGNTAVICGFILLVRREGRLSPADAIVLHLCSANLVVVSVRCLLEVLATFRIHNVFDDAGCRAVIFLHRTARSLSIWLTFLLTALQCLSVAPPGSRRAAARALLARSLPAIFLALWLINTSMSVASLLYSIGARNDSRLLQNAINVEFCFLSFPSRLARDANGAAQVARDVVPMVLMAAGSLVLLVYLVRQRRRVQGLRGTAGGAAERRAAVTVVTLVSLYLLVFGLDNGLWVYTLTVSHTLSSALITDLRLFFTSLYTAVSPLLILVSNTRLRCGKQPETMH
Protein: RING-type E3 ubiquitin transferase (EC 2.3.2.27) (A0A0R4ICA2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- SUMO-conjugating enzyme UBC9-A
- Small ubiquitin-related modifier 1
Sequence:
MAPSKMKLRVRKKDSASKTSQRLLANASPDSKCPICLDGFNNVASLDRCLHQFCFRCIHEWSKNKAECPLCKQPFHSIFHSVKGENDFKEFVLWPPENGAANANAADPSERVLRPRVLRRRERRSNRVQTPAPSSTPPIEDDVMFDGLSDAAALAENQDVQQMMLRLTARRAGRGEGRSLRRLREQDVVAFRRALYRTGVRVRSARDASRQRDISASFLRQNPGCLRRLLPWLQRELTVLYGSHGSLVNIVQNVIISRIMNYNMEESIIRDELRPFLLARTDHFLHELVSFARSSLNMEAYDLQAVYDCPAPSYEEGSSSDLSVIAISEDEEDNDSENNVIENPSAVQERIASVATASGTDSLLSQSAWDDETPGPSYSSILQSSNQSQDEGAEPSSSTAPPLASTDGTDPAAISAADEEEECLIVGYVKPMAERTPELVQLSSDSSEEEEQQAAATETPATVTKSETGQSQLPLPSHMKPLSPSSFAGPAPSCSPQANPSVPQEILSFSRERESDYYSSHGHRSRLASWSELRVHGRRKDRSHRHNKEKAKSIEQIQQPTTLECSPMHSPQSWSGQSSAVSICSISPGSPSYDSDYSPSPKTKGRKHSCRVQERIRQSPSYSGRKSTKERMSRSPDLDLFIGSHHPRESKRHRKRRKRSVSSSSADSHSEKSCLDKPSGKRKYKTRHLERAAQRQHEEGNPSKEKRSKLRSRDRSPSVEIIYERRAPDPHWVSRKKKKKHRKRRKDLDSPTVITIDSDSDRTIDCLDRVMDVIDQTAADIEQRDGTSEQAETCTVASSNLFSESSSPVRPSDPTNEQSLNLDDCVVDVVDQSSSDCSHNIDSSNHEEIVPDPFPMSSITTAPSSDTRLLESILQDLEEFLPAEEPEIGQSACARSPVQQDLTSVPPKDQSDTGGDVDNSENKTTGGDEPQEMATNTAS
Protein: Nucleoporin like 1 (Nucleoporin p58/p45) (Q6NUZ9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus, nuclear pore complex {ECO:0000256|ARBA:ARBA00004567}.
Interaction partners:
Sequence:
MSSFNFGTTTLGTTGAPAAAGGGGFSFGAATSTPAAGTGGFSFGGFGAQTSTPAPATTSTTSTLGFGTSLFAQKPTTGFSLSTPASAAASTSGLSLGSLTTSTAASTGFSLGFGKPAASATPFSLTTTTASAPAATGLSLGSVLTSTVPQTSSTGFSLNLGAAAATSSAPASGFSFGSSLFSNPTLTGLGQSTLGGPLSLGGLVSTSVATTSAPAPSLGLGGVDFSTSSEKNTDKLSSTRPEDSKALKDENLPAPICQDVDNFQKFVKEQKQVQEEISRMSSKPILKVQEDIKMLRQLLSVCASGLQRNSLSIDKLKLETSQELKNADIALRTQKTPPGLQHENTAPSDYFRALVEQFEVQLQQYRQQIEELENHLTTQGSGSHITPQDLSMAMQKLYQTFVALAAQLQGVHENVKTLKHQYLGYRRAFLEDSTDIFESKRVAGKKWQSSPRVTTGPAPFGSVPNAAAVAMAATLTQQQQPAPGPQAPLGASFGTPFSSGIGSSMGSSSLGGFGTSNTSGFNFSNPGINASAGLTFGVSNTQTPGFGAGGPLLQLKKPPAGNKRGKR
Protein: Carbohydrate sulfotransferase 7 (EC 2.8.2.-) (EC 2.8.2.17) (Chondroitin 6-sulfotransferase 2) (C6ST-2) (Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5) (GST-5) (N-acetylglucosamine 6-O-sulfotransferase 4) (GlcNAc6ST-4) (Gn6st-4) (Q9NS84)
Organism: Homo sapiens (Human)
Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues. Preferentially acts on mannose-linked GlcNAc. Also able to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Also acts on core 2 mucin-type oligosaccharide and N-acetyllactosamine oligomer with a lower efficiency. Has weak or no activity toward keratan sulfate and oligosaccharides containing the Galbeta1-4GlcNAc. Catalyzes 6-O-sulfation of beta-benzyl GlcNAc but not alpha- or beta-benzyl GalNAc.
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Interaction partners:
- KRAB domain-containing protein 4
- Carbohydrate sulfotransferase 3
- Sodium/hydrogen exchanger 7
- Zinc finger protein 674
- Carbohydrate sulfotransferase 12
- Carbohydrate sulfotransferase 13
- Carbohydrate sulfotransferase 15
- Chondroitin sulfate N-acetylgalactosaminyltransferase 2
Sequence:
MKGRRRRRREYCKFALLLVLYTLVLLLVPSVLDGGRDGDKGAEHCPGLQRSLGVWSLEAAAAGEREQGAEARAAEEGGANQSPRFPSNLSGAVGEAVSREKQHIYVHATWRTGSSFLGELFNQHPDVFYLYEPMWHLWQALYPGDAESLQGALRDMLRSLFRCDFSVLRLYAPPGDPAARAPDTANLTTAALFRWRTNKVICSPPLCPGAPRARAEVGLVEDTACERSCPPVAIRALEAECRKYPVVVIKDVRLLDLGVLVPLLRDPGLNLKVVQLFRDPRAVHNSRLKSRQGLLRESIQVLRTRQRGDRFHRVLLAHGVGARPGGQSRALPAAPRADFFLTGALEVICEAWLRDLLFARGAPAWLRRRYLRLRYEDLVRQPRAQLRRLLRFSGLRALAALDAFALNMTRGAAYGADRPFHLSARDAREAVHAWRERLSREQVRQVEAACAPAMRLLAYPRSGEEGDAEQPREGETPLEMDADGAT
Protein: Probable sulfate permease C869.05c (Q9URY8)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: High affinity uptake of sulfate into the cell.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Probable phosphoadenosine phosphosulfate reductase
- Adenylyl-sulfate kinase
- Probable sulfate permease C3H7.02
- Siroheme biosynthesis protein met8
- Uncharacterized transporter SPBPB10D8.04c
- Vacuolar basic amino acid transporter vsb1
- GTP-binding protein ypt1
- Probable sulfite reductase flavoprotein component
- Putative glutamine amidotransferase PB2B2.05
- Protein isd11
Sequence:
MRAWGWVRNKFSSEDDYNDGASNKDYPDRFNEFDNSQNDHNDYTQNNAQFQNAQTTTFGRTISRVKAYYEIPEDDELDELASIPQWFKKNVTSNIFKNFLHYLKSLFPIIEWLPNYNPYWLINDLIAGITVGCVVVPQGMSYAKVATLPSEYGLYSSFVGVAIYCFFATSKDVSIGPVAVMSLITAKVIANVMAKDETYTAPQIATCLALLAGAITCGIGLLRLGFIIEFIPVPAVAGFTTGSALNILSGQVPALMGYKNKVTAKATYMVIIQSLKHLPDTTVDAAFGLVSLFILFFTKYMCQYLGKRYPRWQQAFFLTNTLRSAVVVIVGTAISYAICKHHRSDPPISIIKTVPRGFQHVGVPLITKKLCRDLASELPVSVIVLLLEHISIAKSFGRVNDYRIVPDQELIAMGVTNLIGIFFNAYPATGSFSRSAIKAKAGVKTPIAGIFTAAVVILSLYCLTDAFYYIPNAILSAVIIHAVTDLILPMKQTILFWRLQPLEACIFFISVIVSVFSSIENGIYVSVCLAAALLLLRIAKPHGSFLGKIQAANKYGSDNIANVRDIYVPLEMKEENPNLEIQSPPPGVFIFRLQESFTYPNASRVSTMISRRIKDLTRRGIDNIYVKDIDRPWNVPRQRKKKENSEIEDLRPLLQAIIFDFSAVNNLDTTAVQSLIDIRKELEIYANETVEFHFTNIRSGWIKRTLVAAGFGKPKGHAVDASVCVEVAAPLRDANLSAESSRNLSRIITPIYDDEEGNVSGHIYELDGKNNSDLSMHCQKGSNQVEIEFVEFNSRKYPFFHVDVASAVVDLQHRLLSPQKSDSFGSLKEGGTTTIKKIEN
Protein: Condensin complex subunit 3 (Non-SMC condensin I complex, subunit G) (F1QJY8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
Interaction partners:
- Structural maintenance of chromosomes protein
- Condensin complex subunit 1
- Structural maintenance of chromosomes protein
- Condensin complex subunit 2
- Condensin-2 complex subunit D3
- Zinc finger and AT hook domain-containing.
- Condensin-2 complex subunit G2
- Abnormal spindle-like microcephaly-associated protein
- BUB1 mitotic checkpoint serine/threonine kinase
- Kinesin family member 11
Sequence:
MPGDADLQIEEAFRRAQKAHNNKAKLVASLKNGYNKLEDKTQFHEEFIRCLKYAMIIYTREPAVENVIDFVSKFAASFEIPVNEEAEEEEEEEEDNEFLNFLFNFLLESHGANSHAVRFRVCQLVNKLLGSLSENAQIDDDLCDRIHEAMLVRVTDKYPNVRIQAALAMARLQDPTNSDCPTIKAYVLLLENDSNPEVRRAVLSCIAPSAVTLPKIYKRTRDVKEKVRKLAYEVLAEKVHIRALTIAQRVSLLHEGLSDSSDSVKEVVRAHLLPAWLRLLQGDVLQLLHRLDVENCADTAVTALHAIFSMATSPDDLMQNGVRLDERKLIPVNSLTCENVLYWRALCEFVKSKGNEGEELLEQLLPEAAIYAEYLYSFLKSITQLSEAQRADMTQLEMVMTQEFVGQQLILLVGCLDTSEEGGRKRMVAVLQEILVMPNTPVSLIGLLVEKLVNILRDDAQKIQMVAEIISDVREPIFPISEPVDENEKRRKQVRLAEVRVQIMEAKQTLEDCISCQDFSRAAELKDSISQLEELKNQLTLEVSQPAENVKEQRIEKSDPETLLKCLTMCAELFKQMSIKRGVCPTMIALIESLILPSVSNPNPAVRNMAVICLGTAALHSKDLANTHLVLLLQITQLDEPKIRISALRSLIDQLLLNGLDILQDKPVPPTSQTPDSPDISDRQPEKQAEEESPVQSILKMLSEFLDSEVCELRTETAEGLAKLMYCGRILSPKLLSRLVLLWYNPVTEDDQRLRHCLGVFLQLYARASRANQECVEESLLPTMRTLFNAPVTSPLSEVDASNVAELFVELTRPSALVQPAVVQAVSVHDSLALRVCNEILRDVSAPEVRLYCKTLSWLEINIEPGPANNELQLLLKDILQEVKDKYCTRVIEKLCNQLIGDHGSKSASNQDTALLNLDENNGELMNKDETKPKRAKRGQKKAATAKNGKKSYKADMSSDESDEENIPEEVPSVRPSRRAKIAALDKTKQDLTALINQEANGS
Protein: Phenylcoumaran benzylic ether reductase POP1 (PCBER-Pop1) (EC 1.23.1.-) (B9HRL7)
Organism: Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp. trichocarpa)
Function: Oxidoreductase involved in lignan biosynthesis. Catalyzes the NADPH-dependent reduction of phenylcoumaran benzylic ethers. Converts dehydrodiconiferyl alcohol (DDC) to isodihydrodehydrodiconiferyl alcohol (IDDDC), and dihydrodehydrodiconiferyl alcohol (DDDC) to tetrahydrodehydrodiconiferyl alcohol (TDDC).
Interaction partners:
Sequence:
MASKILFIGGTGYIGKFIVEASAKAGHPTFVLVRESTLSNPAKSVVIYNFKNLGVNFLIGDLFDHESLVKAIKQVDVVISTVGHAQLVEQDRIIAAIKEAGNVKRFFPSEFGNDVDRVNAVEPAKSAFATKANVRRAIEAEGIPYTYVSSNFFSGYFLLSFNQPGATAPPRDKVVILGDGNPKAVFNKEDDIATYTIKAVDDPRTLNKILYIKPPANTISFNDLVSLWEKKIGKTLERIYVPEEQLLKNIQEASVPVNVVLSIGHSVFVKGDHTNFEIEPSFGVEASELYPDVKYTTVDEYLKQFV
Protein: Uncharacterized protein (Q57X13)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MHRGPPALLHTVGVATRSKSFAASTKLPGRLTPLPSTSSTLQPTNTLLSSSAGIASLRQLVSASTLTSTSTSGKKRVGSLDAHCRLLSRGTSADSYMPMTSRSFDVFEGNNKQAWLDLKTGWCHLCQEPLGATMGVHIGDRDHTNLQYFLFLYAAHGRRWSSEEVLRSCLATAPTVHNYATRHTTWDHLHVMDDALRRAELEALLFHLTHPPQQALSHVLQGRSPLGFWYSGERMWKLRISRLVTQVFPPISAGMMTNFTQKCWGRSNGERMYDALRLQRIKAYYGWQPYESKEKKAFFVRQLLWELLSVEVRDEVDELTKHMADLALRRMAFEMIFLQSMEYMHKVQYVYDLMGRPTVDELAAMNLL
Protein: Nucleoporin (Q385W3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Nuclear pore complex protein
- Nuclear pore protein
- Uncharacterized protein
- Nucleoporin
- Poly
- Nucleoporin
- Ran-binding protein 1, putative
- RanBD1 domain-containing protein
- Nucleoporin NSP1-like C-terminal domain-containing protein
- Protein transport protein sec13, putative
Sequence:
MYQPLLEAPAGSPSAVVGDRLIGEAAGSLFGGSDRAAFEAQGGAYYPPWRPANANVISGGRYRAAGSGIMATWQRWPLYRLQTVLRPLTSLFPLLRVVFPFAVPGQDRCPQLCAAAFAERVTAISFHPVRMILAAAVNEGNDCSRVVVYDVAEGREECVLTHAFQRQTCCLAWKPLSRDVLAVGCNGGVLLWSLTFNMSPAGQAVLGNGNLTHRSVVNGTESSAPYCLFYRCAKNVVVTCIRFSCRDGRYLACGSAKHAALHFHDIRLQPSKSLLLRNVSVEGATQDVLFADDDSFAIRLVCGTSVLVLLQFPSCAANVVPTAAPVLGVTKARGLGPNYFFLHCHHVEGVFVAHINPFVGVHVIGLISTGIHRGVGGAVRCVASSDRRLFVALETGHLLVMHYGRRGVFTLIPVGTAEIGTECMAVFDGCTYGSLLAVVEADQSVSFVPAYHA
Protein: U6 snRNA-associated Sm-like protein LSm4 (Q9VKW8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU365049}.
Interaction partners:
- U6 snRNA-associated Sm-like protein LSm7
- U6 snRNA-associated Sm-like protein LSm6
- U6 snRNA-associated Sm-like protein LSm8
- U6 snRNA-associated Sm-like protein LSm2
- U6 snRNA-associated Sm-like protein LSm5
- U6 snRNA-associated Sm-like protein LSm1
- U6 snRNA-associated Sm-like protein LSm3
- Small nuclear ribonucleoprotein-associated protein B
- Protein associated with topo II related - 1, isoform A
- Probable small nuclear ribonucleoprotein Sm D2
Sequence:
MLPLSLLKTAQSHPMLVELKNGETYNGHLVSCDSWMNINLRDVICTSKDGDRFWRMPECYIRGSTIKYLRIPDEVIDMVKEDAQAKSRNRTEMNKNRGGNSSQNQRGGRPGGGNRNNVGNRPGQGYGGAANNAMRLGGAAGQGNRLPHAAKNRK
Protein: RNA binding protein fox-1 homolog 2 (B0QYY4)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR037932}.
Interaction partners:
Sequence:
MVQPFTTIPFPPPPQNGIPTEYGVPHTQDYAGQTGEHNLTLYGSTQAHGEQSSNSPSTQNGSLTTEGGAQTDGQQSQTQSSENSESKSTPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKMVTPYANGWKLSPVVGAVYGPELYAASSFQADVSLGNDAAVPLSGRGGINTYIPLIIPGFPYPTAATTAAAFRGAHLRGRGRTVYGAVRAVPPTAIPAYPGVVYQDGFYGADLYIESANCFRSNRVDMQPTDMHSLLLQPQPPLLQPLQPLTVTVMAGCTQPTPTMPLPLPLAMELALWRVYTEVATADLPPTEVT
Protein: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (Complex I-B14.5a) (CI-B14.5a) (NADH-ubiquinone oxidoreductase subunit B14.5a) (Q05752)
Organism: Bos taurus (Bovine)
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular location: Mitochondrion inner membrane {ECO:0000305|PubMed:10852722, ECO:0000305|PubMed:18721790}; Peripheral membrane protein {ECO:0000305}; Matrix side {ECO:0000305}.
Interaction partners:
- NADH dehydrogenase iron-sulfur protein 6, mitochondrial
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
- NADH dehydrogenase flavoprotein 2, mitochondrial
- NADH dehydrogenase iron-sulfur protein 7, mitochondrial
- NADH dehydrogenase 1 beta subcomplex subunit 11, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 11
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 3
- NADH dehydrogenase 1 beta subcomplex subunit 10
- NADH dehydrogenase 1 alpha subcomplex subunit 10, mitochondrial
Sequence:
MASATRFIQWLRNWASGRDLQAKLQLRYQEISKRTQPPPKLPVGPSHKLSNNYYCTRDGRREAMPPSIVMSSQKVLVAGKPAESSAVAASEKKAVSPAPPIKRWELSQDEPYL
Protein: Sulfatase-modifying factor enzyme domain-containing protein (P95060)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Interaction partners:
Sequence:
MLTELVDLPGGSFRMGSTRFYPEEAPIHTVTVRAFAVERHPVTNAQFAEFVSATGYVTVAEQPLDPGLYPGVDAADLCPGAMVFCPTAGPVDLRDWRQWWDWVPGACWRHPFGRDSDIADRAGHPVVQVAYPDAVAYARWAGRRLPTEAEWEYAARGGTTATYAWGDQEKPGGMLMANTWQGRFPYRNDGALGWVGTSPVGRFPANGFGLLDMIGNVWEWTTTEFYPHHRIDPPSTACCAPVKLATAADPTISQTLKGGSHLCAPEYCHRYRPAARSPQSQDTATTHIGFRCVADPVSG
Protein: Photosystem II D2 protein (PSII D2 protein) (EC 1.10.3.9) (Photosystem Q(A) protein) (Q6ENJ1)
Organism: Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea)
Function: Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors. D2 is needed for assembly of a stable PSII complex.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_01383}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01383}.
Interaction partners:
- Photosystem II CP43 reaction center protein
- Photosystem II CP47 reaction center protein
- Cytochrome b559 subunit beta
- Cytochrome b559 subunit alpha
- Photosystem II protein D1
- Photosystem II protein D1
- Uncharacterized protein
- Photosystem II reaction center protein H
- Cytochrome b6-f complex subunit 4
- Photosystem II reaction center protein K
Sequence:
MTIALGRVTKEENDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFALIGFMLRQFELARSVQLRPYNAISFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSAIGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
Protein: Miple2 (Q9U3W4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNLILALTTALHLVLVVLAHNPLSTRGESLSDGIRLVMEKRSGDVVHIRPARGTLEAETVASTTNSDTHRTRNNRKPNKPQEHSQQVGAHKSGSRKLVVAENGGALSSQLPQPNHKQGHKNTDKQQRGGGSKQQRGHSQHHGGNRKGPKAATPENGSTCRYAKSAWSNCDHKTNMRSRVLSLRKGEQNCLPTRTIQKKCKKGCRYEKGEWSQCVGGQITREDKLEPEATGGSDQNCNPVRTVSKKCKANGNSSGGKQHGQSRRTKEQKQKDKGASRISS
Protein: Restriction of telomere capping protein 4 (P53850)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May be involved in a process influencing telomere capping.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Kinesin-related protein SMY1
- Zinc-responsive transcriptional regulator ZAP1
- Zinc finger protein GIS2
- Protein VEL1
- Folic acid synthesis protein FOL1
- VEL1-related protein YOR387C
Sequence:
MVGPGLGINRVRRKGVYSTKKGSGDNLLLMKRQGKHDIHDRESDDLSGHDAFSPSKKRGKIDSITEDEIEVKKLSTVATFDKLSRSFPNSEVQAAKNAALRGKEKEEEKVVSIPLIQNLKNEDIESIKCRNNNLLDGKKLLLEAELSAVEDNQIFSSSFPEDKKLSLQSCLSSKEQIIKKLQVREEYMSKFKLPPMLFSDELLTEVEPFMPIVMDILEGKISSVYYFEAKNAFKNSQKAYLSVDEFRKLNLNKFTAGFYGLKRQLRVGEEIAKRYKRALTHNQPATLKWWGITDFCNYVLAPETLTSFCIYQLNLSNKSCSSKTPNKHPKQQLNEKEYYYDPELRMLAYDLLEDTVEYGIIVADSDPIEQWEAAIEEDRLRELKLDVHNYSSRRWRLDTHD