wanglab/gogpt-training-data huggingface dataset:
Protein: F-box protein At5g46170 (Q9FNK5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MAVIIPRSDPPSRIHPEPPQTLEIDHFDHLPDSILLLVFNKIGDVKALGRCCVVSRRFHSLVPQVDNVVVRVDCVISDDDSSSLSSIKSRSGSSAGSFSAIFRLVVGGIVKPLQALGQFLGTKRSSSSCGGSGSSSSSLSISGDDDGGEIEQGGVTHHSPTQVLKNFDEIRYLRIELPSGELGIDDGVLLKWRAEFGSTLDNCVILGASSVIPPNPMRVSQACDTTTVVEAPGSGSDDNGSIPESFYTNGGLKLRVVWTISSLIAASARHYLLQPIIAEHKTLDSLVLTDSDGQGVLCMNRDQLEELRVKPLAASSASKRTLVPALNMRLWYAPTLELPDGTVLKGATLVAIRPSESKKEVSDISWVSSAFEEPYETAAKMLVKRRTYCLEMNSF
Protein: Mediator of RNA polymerase II transcription subunit 4 (Activator-recruited cofactor 36 kDa component) (ARC36) (Mediator complex subunit 4) (TRAP/SMCC/PC2 subunit p36 subunit) (Vitamin D3 receptor-interacting protein complex 36 kDa component) (DRIP36) (Q9NPJ6)
Organism: Homo sapiens (Human)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Subcellular location: Nucleus.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 10
- Mediator of RNA polymerase II transcription subunit 18
- Mediator of RNA polymerase II transcription subunit 17
- Mediator of RNA polymerase II transcription subunit 31
- Mediator of RNA polymerase II transcription subunit 28
- Mediator of RNA polymerase II transcription subunit 29
- Mediator of RNA polymerase II transcription subunit 7
- Mediator of RNA polymerase II transcription subunit 26
- Mediator of RNA polymerase II transcription subunit 22
- Mediator of RNA polymerase II transcription subunit 23
Sequence:
MAASSSGEKEKERLGGGLGVAGGNSTRERLLSALEDLEVLSRELIEMLAISRNQKLLQAGEENQVLELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVYQAKEKLKSIEKARKGAISSEEIIKYAHRISASNAVCAPLTWVPGDPRRPYPTDLEMRSGLLGQMNNPSTNGVNGHLPGDALAAGRLPDVLAPQYPWQSNDMSMNMLPPNHSSDFLLEPPGHNKENEDDVEIMSTDSSSSSSESD
Protein: Bifunctional pinoresinol-lariciresinol reductase (PLR-Fi1) (PLR3) ((+)-lariciresinol reductase) (EC 1.23.1.2) ((+)-pinoresinol reductase) (EC 1.23.1.1) (P93143)
Organism: Forsythia intermedia (Border forsythia) (Forsythia suspensa x Forsythia viridissima)
Function: Reductase involved in lignan biosynthesis. Catalyzes the enantioselective sequential conversion of (+)-pinoresinol into (+)-lariciresinol and of (+)-lariciresinol into (-)-secoisolariciresinol. Abstracts the 4R-hydride from the NADPH cofactor during catalysis.
Interaction partners:
Sequence:
MGKSKVLIIGGTGYLGRRLVKASLAQGHETYILHRPEIGVDIDKVEMLISFKMQGAHLVSGSFKDFNSLVEAVKLVDVVISAISGVHIRSHQILLQLKLVEAIKEAGNVKRFLPSEFGMDPAKFMDTAMEPGKVTLDEKMVVRKAIEKAGIPFTYVSANCFAGYFLGGLCQFGKILPSRDFVIIHGDGNKKAIYNNEDDIATYAIKTINDPRTLNKTIYISPPKNILSQREVVQTWEKLIGKELQKITLSKEDFLASVKELEYAQQVGLSHYHDVNYQGCLTSFEIGDEEEASKLYPEVKYTSVEEYLKRYV
Protein: Aquaporin NIP1-2 (NOD26-like intrinsic protein 1-2) (AtNIP1;2) (Nodulin-26-like major intrinsic protein 2) (NodLikeMip2) (Protein NLM2) (Q8LFP7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Water channel probably required to promote glycerol permeability and water transport across cell membranes.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Aquaporin SIP1-1
- Probable aquaporin SIP2-1
- Probable aquaporin SIP1-2
- Aluminum-activated malate transporter 1
- ACT domain-containing protein ACR3
- Glycerol-3-phosphate dehydrogenase SDP6, mitochondrial
- At1g02260
- Myelin transcription factor-like protein
Sequence:
MAEISGNGGDARDGAVVVNLKEEDEQQQQQQAIHKPLKKQDSLLSISVPFLQKLMAEVLGTYFLIFAGCAAVAVNTQHDKAVTLPGIAIVWGLTVMVLVYSLGHISGAHFNPAVTIAFASCGRFPLKQVPAYVISQVIGSTLAAATLRLLFGLDQDVCSGKHDVFVGTLPSGSNLQSFVIEFIITFYLMFVISGVATDNRAIGELAGLAVGSTVLLNVIIAGPVSGASMNPGRSLGPAMVYSCYRGLWIYIVSPIVGAVSGAWVYNMVRYTDKPLREITKSGSFLKTVRNGSSR
Protein: Prostaglandin E synthase 3 (EC 5.3.99.3) (Cytosolic prostaglandin E2 synthase) (cPGES) (G1TGF1)
Organism: Oryctolagus cuniculus (Rabbit)
Function: Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q3ZBF7}.
Interaction partners:
- Prostaglandin E synthase
- GST N-terminal domain-containing protein
- Prostaglandin G/H synthase 1
- Prostaglandin G/H synthase 2
- Serine/threonine-protein phosphatase 5
- Stress-induced-phosphoprotein 1
- Glucocorticoid receptor
- peptidylprolyl isomerase
- Prostaglandin I2 synthase
- Hematopoietic prostaglandin D synthase
Sequence:
MQPASAKWYDRRDYVFIEFCVEDSKDVNVNFEKSKLTFSCLGGSDNFKHLNEIDLFHCIDPNDSKHKRTDRSILCCLRKGESGQSWPRLTKERAKLNWLSVDFNNWKDWEDDSDEDMSNFDRFSEMMNNMGGDEDVDLPEVDGADDDSQDSDDEKMPDLE
Protein: Dimethylaniline monooxygenase [N-oxide-forming] 4 (EC 1.14.13.8) (Dimethylaniline oxidase 4) (FMO 1E1) (Hepatic flavin-containing monooxygenase 4) (FMO 4) (P36367)
Organism: Oryctolagus cuniculus (Rabbit)
Function: This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides.
Subcellular location: Microsome membrane {ECO:0000250|UniProtKB:Q8K4B7}; Single-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8K4B7}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- medium-chain acyl-CoA ligase
Sequence:
MAKKVAVIGAGVSGLTSIKCCLDEDLEPTCFERSNDIGGLWKYTETSKDGMTRIYWSLVTNVCKEMSCYSDFPFQEDYPNFMSHSKFWNYLQEFAEHFDLLKYIQFKTTVCSVTKRPDFSKTGQWDVVTETEGKQHRAVFDAVMVCTGKFLNPRLPLESFPGILKFRGQILHCQEYKIPEGFRGQRVLVIGLGNSGGDVAVELSRVAAQVLLSTRTGTWVISRSSNGGYPFNMMITRRCLNVIEQVLPSCFLRWINERQMNKRFNHENYGLSITKGKNPKFIVNDELPTCILCGTVTVKTSVKEFTETSAIFEDGTVEENIDSVIFTTGYVFSFPFLEEPLRSLCMKKMFLYKHVFPSNLERASMAIIGLISLKGSILTGTELQARWATRVFKGLCKIPPPQQLMAEVTKKEELIKRGVIKDTSEEKLSYIPYMDDLAACIGTKPNIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKWDGARNAILTQWDRTLKPLKTRTVSSDSSKSASLSHYLKVWGAPLLLASVLLICKSSHFLKSVRDKLQNRIFPYLVL
Protein: Meiotically up-regulated gene 93 protein (Q96WW2)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has a role in meiosis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}. Note=Localizes to the barrier septum.
Interaction partners:
- Uncharacterized protein PB8E5.10
Sequence:
MEEKENVNLVEKSNYVALENTREIDVFDEFLNAIGNENTITPVYADSSLTHLRKKSYTKVVHDCTYALVINPYDKKVIWRRGLAYLRLGHPHLANRDWEHSLELDPNNTYIQKSLHRLKEVYYIYRECAETWQLRHLRVASSQQLPVGLRKQYPNIIRGKIWWKKVHDNCQLCGQQCELKKENLSAMRSMLYMANTYAKDDTENHSPSAQIGIESSEDELENKITKGEHSLLVPEELYRSNYPCPQNIDQFLYMIKVLSAPCLYIETFSFPISTINQLFKAHGMSVEQLNLFLKSIHYIGLCSRFCKQWSDKARSLMQALSGLPWFSFVVQHCLHITAAQILLHIPDIQEEEFRNWHVSKKPINNTDLSSEFEIAEIPINCYT
Protein: Dephospho-CoA kinase domain-containing protein (Q8BHC4)
Organism: Mus musculus (Mouse)
Interaction partners:
- Endonuclease 8-like 3
- Glycylpeptide N-tetradecanoyltransferase 1
- Bifunctional coenzyme A synthase
Sequence:
MFLVGLTGGIASGKSSVIQVFQQLGCAVIDVDVIARHVVQPGYPAHRRIVEAFGTEVLLENGDIDRKVLGDLIFNQPDRRQLLNSITHPEIRKEMMKETFKYFLRGYRYVILDIPLLFETKKLLKYMKHTVVVYCDRDTQLARLMKRNNLNREDAEARINAQLPLKDKARMANHVLDNSGEWSLTRRQAILLHAKLERSMEYLPLRLGFLTGLAGIASLLYLLTRYLLPSP
Protein: Menaquinone reductase, molybdopterin-binding-like subunit (Quinone reductase complex subunit B) (Type I cytochrome c3:menaquinone oxidoreductase subunit B) (Q72E84)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Function: Component of the respiratory Qrc complex, that catalyzes the reduction of the menaquinone pool using electrons transferred from the reduced periplasmic cytochrome c3, and which is probably involved in sulfate respiration. Is likely essential for growth on H(2) or formate since the periplasmic hydrogenases and/or formate dehydrogenases act as primary electron donors for the Qrc complex. The function of the QrcB subunit is unknown; in the absence of a catalytic site, it may provide a structural scaffold for the other subunits.
Subcellular location: Periplasm {ECO:0000305|PubMed:20498375}.
Interaction partners:
- Menaquinone reductase, iron-sulfur cluster-binding subunit
- Menaquinone reductase, integral membrane subunit
- Reductase, iron-sulfur binding subunit, putative
- Iron-sulfur cluster-binding protein
- Heterodisulfide reductase, iron-sulfur-binding subunit, putative
- Cytochrome c nitrite reductase subunit NrfH
- Reductase, transmembrane subunit, putative
- Pyridine nucleotide-disulfide oxidoreductase
- Formate dehydrogenase, beta subunit, putative
- Formate dehydrogenase, beta subunit, putative
Sequence:
MALDRRGFLKFIGGATAGILATPVVWKGLDDVSIWSQNWSWIPRNIKGANSYVPTVSKLCPTGIGVRVRLVDGRPVRVIGNPEHPLSKGGVSSIAAAEVQMLYSPARMKRPLKRSPDGAYVMISWEEAEAMLLDGLKAAKGGDALACISGDDNGTINELLSAFVQQSGSKSFFLMPGEAQPAAKAWDLMGGEGQIGYDIEKSDFVLAIGANVLEAWGTAIRNRHAFGASHPHGAEPTAQFVYAGPVLNNTATGADDWLPIRPGTESAFALGLAHLLIKAGASSSAPDFDAFRSLAASFSPEKVAAQTGVDAKALTALAQALAKAKHPLVIVGSEFSQGAGAAPVMAGIALNMLLGSVNRDGGLRALPVARKVVPAGMDRKAMLQQDLTLWASAIASGKAKAPKAMLVYEANPVYALPQGSAFKDTLAKVPFKVAFTSFLDETAMQCDLVIPVSMGLERLDDVCTPYGCGEVVYSLATPVTAPLFDTKPAGDALIALGGKLGLDLGVASFEDMLKAKAAAHGADFDKLAEGTAFTSRATVGANLSFRPDVLSKALDVKAPALPLALAPVMKLNMGTSKTAIPPFNTKTIRRWEVQGKEGYVMLNGATARKLGLAQHDRVVLSNPTGKVTVRVNIFEGVMNDTVAMPLGFGHTAFDEFSKGKGENVMHLLAPSTEPVTGLAVWTGAGVNIAKA
Protein: Cyclin-A2 (Q6NV43)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MSTQGSAVHDSDIHNQENMLSRLRGAAAKNRVENRENVNPNPKAANNRTVLGELENNQRRQLGLRGAKQGSGPQIIACKPEENARSFGERPSNRQPAAFQIHVDEPDGACSKKAPLQRSTMDCSPLTLNPTVTRLRQPLATIDLPLEASFDSPMDMSVIDCEERPTNVNEVSDYAAEIHTHLREMEVKSKPKAGYMRKQPDITNSMRAILVDWLVEVGEEYKLQNETLYLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLTVLSFDLAAPTINQFLTQYFLHQPVSSKVESLSMFLGELSLIDCDPFLKYLPSQMAAAAFILANHTLASGSWSKSLVDLTGYSLEDLLPCVQDLHQTYLAASQHAQQAVREKYKGSKYHEVSLIEPPEKLMLN
Protein: C2H2-type zinc finger family protein (Putative C2H2-type zinc finger protein) (O81013)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- C2H2 and C2HC zinc fingers superfamily protein
- HAT family dimerization domain-containing protein
- Ac-like transposase
- C2H2-type zinc finger family protein
- Zinc finger protein ZAT8
- Zinc finger protein ZAT5
- Zinc finger protein ZAT18
- Zinc finger protein ZAT11
- Zinc finger protein AZF3
- Zinc finger protein ZAT7
Sequence:
MKRTRDLYGDESSSSESEEFHREKIRVKVKLPEERSEDEDESPQPQRKHFCVICEKQFSSGKAYGGHVRIHSIEYNNKGKMKKMKKMKLKKKKKRKIGLVKKEKEKEIDLARTDVEGKIRCCLCGKEFQTMHSLFGHMRRHPDRTWKGIRPPPPSEKFNLSYLDDDVDDEDEDDDDVMSRSMMMSDVPEDVQGAACILMMLSYASRNYWAGIEESPKSEVRSSSFYKDDEGKDKVLGDSRMDEKKGLIVDMKIKMEMEVKVNSPRDEAKRSLGFDLNQPPYHEDHP
Protein: Beta-defensin 3 (BD-3) (mBD-3) (Defensin, beta 3) (Q9WTL0)
Organism: Mus musculus (Mouse)
Function: Antimicrobial activity against Gram-negative bacteria E.coli and P.aeruginosa.
Subcellular location: Secreted.
Interaction partners:
- Beta-defensin 2
- Small proline-rich protein 2I
- Beta-defensin 1
Sequence:
MRIHYLLFAFLLVLLSPPAAFSKKINNPVSCLRKGGRCWNRCIGNTRQIGSCGVPFLKCCKRK
Protein: Alpha-amylase (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase) (allergen Aca s 4) (B0KZK1)
Organism: Acarus siro (Flour mite) (Tyroglyphus farinae)
Subcellular location: Secreted {ECO:0000305|PubMed:22292590}.
Interaction partners:
Sequence:
MAHLLLAVVAITLALSQSVFGGSPYSNPHFTGSRSVITHLMQWKFDDIAAECERFLGPKGYGGIQLSPVNEHAVLGNRPWYELYQPVGYKIQSRSGNEEQFKGMVQRCNKVGVRIYVDIVMNHMSGAQEGHGNCWFKLQWHHDVSRCSLLVPNDFHGRESCHTDNMDIKNYDNPEEARNCRLSGLRDLKQSSEYVRQKQADFLNHLIDLGVAGSRSDASKHMWPGDLEAIYGKLHNLNTAYFPANSRPFIYHEVIYYGGDGIKSSDYTKLGRAIEFHFYRDIANVVRRHNQLKTVKNFGQPWGMVPSDDALVMVDSHDLQRFHTGQVGVNINYFESRLLKVATAFMLAWPYGVPRVMSSYHWDQKIEDGKDKNDWIGPPSDGSGNILSVTPQPDDTCNKEWICEHRWRQIYNMVHFRNVAGNEAVSHWWDNGDYQIAFGRGSKAFIAINLQDGQGLNRKLATGLPQGTYCDLVTGNLAGGKCTGGTVTVDGSGNADINIAKTAEDPFVAIHVEAKLH
Protein: Ensconsin, isoform K (M9PE93)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MASLGGQHGNISTNPEVENTAKRPESREGSAERKDREEKLKYARDRQNEERHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRTRDTEKRHQVEERKKAIFEAEKERREYILKKNQERESRIEVKKRDRNSIGFAFGSSTPRLLDVPADYGLVSPSAFWGQRRSTSISNVAGASLTRRSSERELADSGAKKRASSSTDRQDEDSVDSSPMVFRSVYRRKTDLMPTIPSPRDGHYGSRGSLSSTPARTPGRAYSMNRLDQLAQPIRRNGEHMRAILERERRERELEMLDETASLGGGGGRRGAGSSARARRAGSAGSGSSSAAGIMSRSMTHLAGGGGQRERGKYSLGGGISTSFRPLASGAGGQRDSTSSRSGNATPGGHFNNSRPGSAMSTSTNMSTSGLVPRRPATAPRKPRPASIAGTGMSLEEINKLKRDQKPPVKTTAASPSAQTTPKRTANLMSTSLIVTSSSSRLSSAEKKTPSKREPPVPKAASASKALPSRTASSERISRLTKEPKTKDTSAMTRSMIVTSSSTSTITKPAPAPVAPTSAPVPEQNGVAKEVEKTTADEPVPEAEVPTEAPVVVPSVSKAEKEALNTEKTEEGARQEEEQILAVESVPEALVTSINVEEKSDEGNEKEVPKPQEQAAPKKPSRSKENSEVRELTPPEGADLMTASMMAKKITTEEEAKAALAERRRLAREEAERQAELERQRLEAERLAEIKAQEEEAERQRLFEEESTRLAEEQRRGEEERLRKAIEEAQQREEEEKRRREEEEKQRVEREEAEKKAKEEAEKQRVEVAERLKREEKEREERRKRVEAIMLRTRKGGAATTPSKDANDKAAPAATAPENNSSSNSSVTGSSNNSAEGSPSAADSTPAPTATETVQEAPNSQAMYEQSVLDKENSLINSFSTMIIDENAKNLQQVSNGKLLVDFESTNTVPAVANGNGHIENVNNKNDINLLQDVVAPVATQLIDLSIESQDLHLNNNNSLLTSTAATTTLVTADSHENKDISLL
Protein: AP complex subunit beta (A0A1D8PFU6)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004308}.
Interaction partners:
- AP-2 complex subunit alpha
- Apm4p
- AP complex subunit sigma
- AP-1 complex subunit gamma
- Clathrin heavy chain
- Apm1p
- AP complex subunit sigma
- MHD domain-containing protein
- Clathrin light chain
- Helicase
Sequence:
MDLASLIFSNRVNTCADISLQLQSNSLFFFPSFHKSNIIWSSLFVILFFFKTKLNKTLTSSTHLFIIISYNTIDIRKMSDGKLFTRSKTTELRTELEQAFKKSKPVVRVKVVLKKVLANIILNNHEVTNLMKDIIPLMKIDDLEVRKLCCEYISTYATTNPDAEDAIPFFSRFHSDPNPLLRVLSLKTMVSINRKEFLNLSITSCKRSFSDKDPDVRKSAAYAAGQIYQHDPARAEREGLIELLNQSLYDENSSVISSALASLGTVIENSKTLNLKIDKNHALTLIKLLRATNEWQQTYILNALMSYTPQNEDEALNLIEAVLPSLQHENSSVVMNAIKVVIYYCNYARNPELRLPVLPKRLGTSLVSLLSKPAETQFLVLRNVILLLLGRKEFVHFDVEMFYCRFDDPIYVKDTKLEIIYLLANESNVGSVLRELEEYATEVDVSMARKAIRAFGNLAVKLENAAEQCVEVICDLVSNGISYIVQESAIVIKNILRKYPGQFEFAISELIKHYKLIDEPDAKTAFVWILGQYCQNIKESKSILEDFITSFKDDPLDVQYATLTAVAKYYLKFPEQGESVILRVLKWATEEVDNPDIRDRGYIYWRLLSSEHASGPNGEFQLNTKKIILNDNPVITSENDNINPVILEELELNIGTLASIYLKPVQTVFRLSKHKELPYSPALQRRNSFHSGVATPQPQSRNSKEHSPGAGAGVSRRMSYRRTNSDNGSQRSTHFDETTNTQQHMPRENLAQKFSRKASFITNRIKS
Protein: At4g31350 (Core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein) (Glycosyltransferase) (Q8GS18)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
Interaction partners:
Sequence:
MSESRQRPPFKGPRWIITLVVLVTVVVITAFIYPPRNSVACYMFSGPGCPLYQQFLFVPTRELTDSEAAAQVVMNEIMNLPQSKTANPKLAFMFLTPGTLPFEPLWEMFFRGHENKFSVYVHASKKSPVHTSSYFVGRDIHSHKVAWGQISMVDAERRLLAHALVDPDNQHFILLSDSCVPLFDFNYIYNHLIFANLSFIDCFEDPGPHGSGRYSQHMLPEVEKKDFRKGSQWFSMKRRHAIVVMADSLYYTKFKLYCRPNMEGRNCYADEHYFPTLFNMIDPDGIANWSVTHVDWSEGKWHPKLYNARDITPYLIRKIKSIQLAYHVTSDLKKVTTVKPCLWKGEQRPCYLFARKFNPETLDRLMYLFPNYTSLV
Protein: Insulin-like peptide INSL6 (Insulin-like peptide 6) [Cleaved into: Insulin-like peptide INSL6 B chain; Insulin-like peptide INSL6 A chain] (Q9QY05)
Organism: Mus musculus (Mouse)
Function: May have a role in sperm development and fertilization.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Relaxin-3
- Insulin-like peptide INSL5
- Prorelaxin 1
- Insulin-like 3
Sequence:
MKQLCCSCLLWLGLLLTPFSREEEEESRPRKLCGRHLLIEVIKLCGQSDWSRFEMEEQSPMTQFFPHYSRKGKAFNPHPSSSAWRRFTNPVPAGVSQKKGTHTWEPQSLPDYQFEKTELLPKARVFSYHSGKPYVKSVQLQKKSTNKMNTFRSLFWGNHSQRKRRGFADKCCVIGCTKEEMAVACLPFVDF
Protein: Small RNA degrading nuclease 3 (EC 3.1.-.-) (Q8RXK2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: 3'-5' exonuclease degrading single-stranded small RNAs.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 6
- Pre-mRNA-processing protein 40A
- DNA gyrase subunit A, chloroplastic/mitochondrial
- rRNA 2'-O-methyltransferase fibrillarin 2
- Mediator of RNA polymerase II transcription subunit 19a
- Mediator-associated protein 2
- Heat shock 70 kDa protein BIP2
- Heat shock 70 kDa protein BIP3
- Heat shock 70 kDa protein BIP1
- Mediator of RNA polymerase II transcription subunit 25
Sequence:
MEHKLATAEKKLLVDLVKLVQKRGLEGENGGWKEFLNVYDKKLGSSLSDPARRSNDVLVAFLLTFKKKEDLQLIARVMQCGANRELIEKFKQETPDKETPEQRLVRLTITHDDYPGNYTFPSYAEDWYVTELGKKKSKVIKSTRMLSIDCEMVTCEDGSQALVRVGAVDRDLKVVLDKFVKPDKPVIDYKTDITGVTAEDLERATLSVADIQKKLRRFLSVGTILVGHGLHNDLQVLRIDHARVIDTSYVFEFVDAPKTQRPSLNNLCKSVLGQEVRMDGAAHNCVHDAAAAMKLVLAAVEKGAATLIQPTEEMMVAEKRRQEARQEAGKAQLFLHKIPHDVPSEELHGVLSGNFTLVVKPPKTGGYSTAVVDFSSPEEANEAFENVEGDVAKDKSGLPQKKAVLKLSSGLAVSLFVRKMVQDDSPCEISTSERARAEENNVSSKRQKTEDETEETKEATVNQREADKTKLFLHKIPHDVPSQELHGVLNGDFTLDVKPPKRKGGYYNAVVDFNSPEEANEAFENVEGDVVKDKTGLPQKMVVFKLSSGSGVSLYVRKMVHDDSPGEISTTKRARTEESNMSSKRQKTEDESEETKEANAKQREADKTKLLLHKIPLNVPSQELKVVITGQFTLEVMPPKRKGRYYNAVVTFNSPEEANKAFEKVKGEAVKEKGGLAQKMVAFKLSSGSGACLYVRKMVQDESEETKEANANHCEDDHLKEMEELKEKLKAMEFAISCEGHSKEIEELKQKLNAKEHQIQAQDKIIANLKMKLEKKQSKSRS
Protein: Interleukin 4/13A (Interleukin-4 like) (E7FKY2)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
Sequence:
MKTAILLLSVAMVLFDSGTLPANAAAHRQHRSHNSNLEAIISMAGQYTHTLSEELLETLLIDVTHLTATTTKCKEFFCEAETILASVKNDAFGEEGKIVRHLRVYNKLQKCTVVKSQDQVEGNQVELRRLLLDLKECGQKINSKP
Protein: Camp independent regulatory protein (AFU_orthologue AFUA_6G04490) (Q5AYQ2)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Phosphatidyl synthase
Sequence:
MVNGNSTVLEPTFNGYVATTHDALILFEACLTGVLHHVPRRPHDRERSHLVRSGAVFIYEENSSGIKRWTDGVTWSPSRILGNFLVYRELEKPFPPGEKKRAMKKTTRRPLTSGRPGEPYARQDSNGGSYSPSPTASGYGAERTHQSEIERALVGSLVDSYGFKEMGLVKKTMSVTVSGVTHHLVSYYSVEDVTRGVLAPPSAVEALKYVRPRPELTQKQSFRAPIDELEHVGMEVTSDPSHPFFPYRSQMVPTPPYSIPAPQQDFYMQQHHYAPVTHPAQPNQVATFTLGGPSPTQQAYLPTPTAPTHIPQPQKQEDYTQFRAQGPYATGFDPLGHNALSSSLQAGIPPLTNPINERARSQSDQSQAAYRNSSISSRSVATDATSPMDPSTPAYSRGSSFSLASQLDGSAHSPLEHRGMSFDASIPRRDSHQISAQFYPGSRSTSVLSQCTSACDSRQLPSHDLGGGCSAADVIP
Protein: Origin recognition complex subunit 5 (PfORC5) (EC 3.6.4.-) (O96237)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Component of the origin recognition complex (ORC) that binds origins of replication.
Subcellular location: Nucleus {ECO:0000269|PubMed:18554328}. Note=During early-to mid replicating trophozoite stages, colocalizes with PCNA1 and ORC1 to distinct nuclear foci which probably are DNA replication origin sites (PubMed:18554328). Dissociates from PCNA1 during the late schizont stage (PubMed:18554328). {ECO:0000269|PubMed:18554328}.
Interaction partners:
- Origin recognition complex subunit 2
- Origin recognition complex subunit 1
- DNA helicase
- ATPase AAA-type core domain-containing protein
- Origin recognition complex subunit 1
- DNA replication licensing factor MCM3
- histone acetyltransferase
- Uncharacterized protein
- Protein kinase, putative
- DNA helicase
Sequence:
MYKIKNNESDINSDDCNETAQECIYGFSSPKKSRKESPIFVQNNDDTCSSNNIYEKKTCSNTSASSVKKYDKKEQSLCSDINNYNKVNIEGLKINERNYDRINNSEEETNINDDNNDDNNGDYDDDNNSDDDDDNDDNNNNDDNNNDDDEDVDDFEDIKENDEYKDPTYSDIYKEAKKCNIRCENIMNSSVNKKNLEEINESDPLNSSDNSMTSSSEESCSEESDKESDKESDKDGNLYDEELNEIIEEGYFKELIPAIPHDILQAYISCLKICGFERQVQLHRLINLLGDLRDPISVIQILGLPGMGKTKVVKNFIKLTNVPFAYVNCLMAVYQSGRSAKNVIYHTILKDLSINLLNEFNEYKKINNITNYSYDPTKLVPNHVSNTDNFFSILHKLLSFKPEDILNNKRTTENIRSPSNSNNNKKKKKEQNDSTGKNSKEECNNNEDDDDDNNKNNFNNNNSNNVRFNSNTNYYKDKLYDRSVVFILDNIRYLVRTHPDLFYALTRIHEYIKGPYNDVTKANKTTRGLCIILINRSPLPDEIFDGLPQPPTVWFDSYTSEMCKNILYRLYNSMCFESLLTYNDKDLKIYYVKHNKNEFLIKRNDVILENDVIYDIWCRYVDYIINVSYKDYKSDFHELLFICSHMWPLFIKPILDGVLEPIVENMNALQRNIDTHIRVATYNHSSHFTFELIDSVFLNENNLKNKIDLSFYSKILLVGAYLASRNLPLTDKRFFNATVKGGAFTLPKKRKGKNKNESILTLLSKSIPKNFTFIRWLCLTDCLLVCFFDEQLILNSLICQQINTLIQLGFISFSSPNNLSCLVRNSLMNGVQWSGYCGSALLNTTTNFSSLTNNIFCETNNSMTYESLDPYTKLVIQVPEETIRNISKEMKIPLDELII
Protein: Protein bicaudal C homolog 1 (Bic-C) (Q9H694)
Organism: Homo sapiens (Human)
Function: Putative RNA-binding protein. Acts as a negative regulator of Wnt signaling. May be involved in regulating gene expression during embryonic development.
Subcellular location: Cytoplasm {ECO:0000250}.
Interaction partners:
- Ankyrin repeat and SAM domain-containing protein 3
- Periphilin-1
Sequence:
MAAQGEPGYLAAQSDPGSNSERSTDSPVPGSEDDLVAGATLHSPEWSEERFRVDRKKLEAMLQAAAEGKGRSGEDFFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPVPDPNSPSIQHISQTYNISVSFKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPSNPQKKSTVYLQGTIESVCLARQYLMGCLPLVLMFDMKEEIEVDPQFIAQLMEQLDVFISIKPKPKQPSKSVIVKSVERNALNMYEARKCLLGLESSGVTIATSPSPASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPNSLLNALNSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPTYGHTAPSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSANHGDPSIQTSGSEQTSPKSSPTEGCNDAFVEVGMPRSPSHSGNAGDLKQMMCPSKVSCAKRQTVELLQGTKNSHLHSTDRLLSDPELSATESPLADKKAPGSERAAERAAAAQQNSERAHLAPRSSYVNMQAFDYEQKKLLATKAMLKKPVVTEVRTPTNTWSGLGFSKSMPAETIKELRRANHVSYKPTMTTTYEGSSMSLSRSNSREHLGGGSESDNWRDRNGIGPGSHSEFAASIGSPKRKQNKSTEHYLSSSNYMDCISSLTGSNGCNLNSSFKGSDLPELFSKLGLGKYTDVFQQQEIDLQTFLTLTDQDLKELGITTFGARRKMLLAISELNKNRRKLFESPNARTSFLEGGASGRLPRQYHSDIASVSGRW
Protein: Protein distal antenna-related (Q9VBW9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Probable transcription factor with a role in the retinal determination (RD) network. Regulates ato expression and is required for normal R8 induction and differentiation. Danr appears to repress Dan expression, but Dan is required for Danr expression anterior to the morphogenetic furrow (MF). Dan and Danr lie downstream of so and require dac function for highest levels of expression. Contributes to differentiation of antenna-specific characteristics; effector gene that acts downstream of homothorax (hth), Distal-less (Dll), cut (ct) and spineless (ss) genes to control differentiation of distal antennal structures.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00320, ECO:0000269|PubMed:12571108}.
Interaction partners:
- Protein distal antenna
- Homeobox protein homothorax
- Protein teashirt
Sequence:
MDISAYQHMNIRMSTRGKRPLRNLTPNDKVRAIQRIHNGETKASVSRDIGVPESTLRGWCKNEQKLRFMCRQLGPDHLGLDTPPEKRAKFELQLQLPPKFVALPPNYEELGFGALPYSPADYPVQNESLLEKLSLVEFVKKNGGLHPEGALHPGQAGVMDYSNNMLHQLNLLALLNSKLTPQTADVLVDAQPKSEDNKVIDSPAASEDYSKNNYPLLSVKNWAKDPAKRVNSANQPEQVNDKNNNALEANSSAPQALVTEQAKTPMFSDTTMPLLPAPFPNPADLAPVIAPVTPANAPPTGTDNQGAALLDWCKLFNASLNFLAFAAAAASMQPGGGGPGGPSYNPNQMASGGSEPDLETYPFNEALLKRLSPLAHSEASNESYCDSEPEDLSVRSCASKASSRSHTPDKSVGSSDAEQ
Protein: Resuscitation-promoting factor RpfD (EC 3.-.-.-) (P9WG27)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Factor that stimulates resuscitation of dormant cells. Has peptidoglycan (PG) hydrolytic activity. Active in the pM concentration range. Has little to no effect on actively-growing cells. PG fragments could either directly activate the resuscitation pathway of dormant bacteria or serve as a substrate for endogenous Rpf, resulting in low molecular weight products with resuscitation activity.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Mce associated membrane protein
- Uncharacterized protein Rv1954A
- Heme chaperone HemW
Sequence:
MTPGLLTTAGAGRPRDRCARIVCTVFIETAVVATMFVALLGLSTISSKADDIDWDAIAQCESGGNWAANTGNGLYGGLQISQATWDSNGGVGSPAAASPQQQIEVADNIMKTQGPGAWPKCSSCSQGDAPLGSLTHILTFLAAETGGCSGSRDD