wanglab/gogpt-training-data huggingface dataset:
Protein: Trafficking protein particle complex subunit 2-like protein (Q9UL33)
Organism: Homo sapiens (Human)
Function: Plays a role in vesicular transport from endoplasmic reticulum to Golgi.
Subcellular location: Cytoplasm, perinuclear region {ECO:0000269|PubMed:19416478}. Endoplasmic reticulum {ECO:0000269|PubMed:19416478}. Golgi apparatus {ECO:0000269|PubMed:19416478}.
Interaction partners:
- Trafficking protein particle complex subunit 10
- Trafficking protein particle complex subunit 3
- Trafficking protein particle complex subunit 6B
- Trafficking protein particle complex subunit 9
- Trafficking protein particle complex subunit 1
- Trafficking protein particle complex subunit 2
- Trafficking protein particle complex subunit 4
- Trafficking protein particle complex subunit 5
- Trafficking protein particle complex subunit 11
- Trafficking protein particle complex subunit 12
Sequence:
MAVCIAVIAKENYPLYIRSTPTENELKFHYMVHTSLDVVDEKISAMGKALVDQRELYLGLLYPTEDYKVYGYVTNSKVKFVMVVDSSNTALRDNEIRSMFRKLHNSYTDVMCNPFYNPGDRIQSSRAFDNMVTSMMIQVC
Protein: Protein YagJ (P77169)
Organism: Escherichia coli (strain K12)
Interaction partners:
Sequence:
MEARVTVAGMGLVMEVQDYFDGEADRLAKAWLAEYTPQIKSLKDERKEAYRQIVEMSTEPQDVDLVRPANKFEMTRVREGEKEADLPVWKHHLLCDESGNYPALLNHWETKVFEIETKREGFAFWYRNPQYTGQSSLGIAYVEAEQYKIVRPDFLFFAEQDGKMVVDLVDPHSLHLADALPKLEGLALYAEHHSDAYRRIESVAEVKGKLRVLDLKRQDVQDAVATAENAETLFSSGLADDYQ
Protein: Prefoldin subunit 5 (Myc modulator 1) (c-Myc-binding protein Mm-1) (Q99471)
Organism: Homo sapiens (Human)
Function: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC.
Subcellular location: [Isoform 1]: Nucleus.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.; SUBCELLULAR LOCATION: [Isoform 3]: Nucleus.
Interaction partners:
- Prefoldin subunit 4
- Prefoldin subunit 3
- Prefoldin subunit 1
- Prefoldin subunit 2
- Prefoldin subunit 6
- T-complex protein 1 subunit delta
- T-complex protein 1 subunit zeta
- T-complex protein 1 subunit gamma
- T-complex protein 1 subunit eta
- T-complex protein 1 subunit beta
Sequence:
MAQSINITELNLPQLEMLKNQLDQEVEFLSTSIAQLKVVQTKYVEAKDCLNVLNKSNEGKELLVPLTSSMYVPGKLHDVEHVLIDVGTGYYVEKTAEDAKDFFKRKIDFLTKQMEKIQPALQEKHAMKQAVMEMMSQKIQQLTALGAAQATAKA
Protein: Putative pentatricopeptide repeat-containing protein At1g64310 (Q9C7V5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MASQTQLRLIIYEFTRKIQTRLNTQKLHSFVTKSKLARDPYFATQLARFYALNDDLISARKLFDVFPERSVFLWNSIIRAYAKAHQFTTVLSLFSQILRSDTRPDNFTYACLARGFSESFDTKGLRCIHGIAIVSGLGFDQICGSAIVKAYSKAGLIVEASKLFCSIPDPDLALWNVMILGYGCCGFWDKGINLFNLMQHRGHQPNCYTMVALTSGLIDPSLLLVAWSVHAFCLKINLDSHSYVGCALVNMYSRCMCIASACSVFNSISEPDLVACSSLITGYSRCGNHKEALHLFAELRMSGKKPDCVLVAIVLGSCAELSDSVSGKEVHSYVIRLGLELDIKVCSALIDMYSKCGLLKCAMSLFAGIPEKNIVSFNSLILGLGLHGFASTAFEKFTEILEMGLIPDEITFSALLCTCCHSGLLNKGQEIFERMKSEFGIEPQTEHYVYMVKLMGMAGKLEEAFEFVMSLQKPIDSGILGALLSCCEVHENTHLAEVVAENIHKNGEERRSVYKVMLSNVYARYGRWDEVERLRDGISESYGGKLPGISWF
Protein: Putative serine carboxypeptidase-like 52 (Q8S8P0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- UDP-glycosyltransferase 79B8
- 3-hydroxyacyl-[acyl-carrier-protein] dehydratase
- Small ribosomal subunit protein uS3z
Sequence:
MRTFSPKLLLLLLLVLRHHAESGSIVKFLPGFEGPLPFELETGYIGIAKYWANDERVREALQIRKGSIGKWIRCNSNIHYDDDIISSIPYHMNNSINGYRSLIYSGDHDMEVPFLATEAWIRSLNYPIIDDWRPWIINNQIAGYTMTYANKMTYATIKASGHTAEYKPAESFIMFQRWISGQPL
Protein: Voltage-gated monoatomic cation channel TMEM109 (Mitsugumin-23) (Mg23) (Transmembrane protein 109) (O77751)
Organism: Oryctolagus cuniculus (Rabbit)
Function: May mediate cellular response to DNA damage by protecting against ultraviolet C-induced cell death (By similarity). Can form voltage-gated calcium and potassium channels in vitro.
Subcellular location: Nucleus outer membrane {ECO:0000269|PubMed:9720923}; Multi-pass membrane protein {ECO:0000305|PubMed:21381722}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:21381722, ECO:0000269|PubMed:9720923}; Multi-pass membrane protein {ECO:0000305|PubMed:21381722}. Sarcoplasmic reticulum membrane {ECO:0000269|PubMed:21381722, ECO:0000269|PubMed:9720923}; Multi-pass membrane protein {ECO:0000269|PubMed:21381722}.
Interaction partners:
- Glutamyl-tRNA
- Lengsin
- Glutamine synthetase
- GMP synthase
- Fatty acid desaturase 6
- Amidophosphoribosyltransferase
- glutamine--fructose-6-phosphate transaminase
- glutamine--fructose-6-phosphate transaminase
- Isoamyl acetate-hydrolyzing esterase 1 homolog
- trans-L-3-hydroxyproline dehydratase
Sequence:
MAGSGSSAPWGKHLLHAVLMVLVALVLLHSALAQSHRDFAPPGQQRREAPVDLLTQIGRSVRETLDTWIGPETMHLISETLSQVMWAISSAISVAFFALSGIAAQLLTALGLDGDHLTQGLKLSPSQVQTFLLWGAGALVVYWLLSLLLGLVLAVLGRILGGLKLVIFLAGFVALVRSVPDPSTRALLLLALLTLYALLSRLTGSRASGAQLEAKVRGLERQVDELRWRQRRAAKGARSVEEE
Protein: Hornerin (Q8VHD8)
Organism: Mus musculus (Mouse)
Function: Component of the epidermal cornified cell envelopes.
Subcellular location: Cytoplasmic granule. Note=Found in keratohyalin granules of the granular cells of the epidermis.
Interaction partners:
- Loricrin
- Filaggrin
- Keratinocyte proline-rich protein
- Desmocollin-1
Sequence:
MPKLLESIVTVIDVFYQYATEYGNCDMLSKEEMKELLVTEFHQILKNPDDPDTVDIIMQNLDRDHNHKVDFTEYLLMILKLTKACNKIIGKDYCQASGSKQKNHSHQHQEEQSKKETENKEQKGSISSSAGENDSYSRGSRGSNKSKSKKLRKGKEQSSKQTTKSNSSDHENSEDYEQGQHESGFSNSSGNGRPSSRKASGFPQPGSEQGQSSSSSTKGSGECYSSGNGKHGSSSGGSAVSGSGHSNTYGKQGTGSRHSSSNRRSRSTSRESSGSQEYSSGSSEEPGFTHGSGRKNSSTCGKNGSYSGQSTGRHQQGFGSSHELESGQSITSANHGSHSNQSSCSGTRECGSSESSMKKTHVSGSGHSSSTGKYTSTSGQNYNSTRQGCGQGKSSGSEQYGASSGQSSGCSSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQQFGSGSGRSSGFSQGGSGQGRSSRGGQQGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASSGQQGSHYSQSSSYGTHNSGGSPSSSQRGHGSRSGRSSGLGQYGSPSGQTSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTSGRSQHQSGSRHGSGSGQFPISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSGLGHYGSTSGQTASSTRQGSGQGQASGSGRCGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRFGSGSGGSSGFSQGRSGQGRSSRGGQQGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASSGQQGSHYSQSSSYGTHNSGGSPSSRPAGGHGSRSGRSSGLGQYGSPSGQTSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTSGRSQHQSGSRHGSGSGQFPISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSGLGHYGSTSGQTASSTRQGSGQGQASGSGRCGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRFGSGSGGSSGFSQGRSGQGRSSRGGQQGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASSGQQGSHYSQSSSYGTHNSGGSPSSSQRGHGSRSGRSSGLGQYGSPSGQTSSSTRQGSGQGQASGSGRYGASSGQTSGCRSGQSTRYGGQGSGSRNSSTQSRGRSTSRESSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTSGRNQHQSGSRHGSGSGQFPISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSGLGHYGSTSGQTASSTRQGSGQGQASGSGRCGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRFGSGSGGSSGFSQGRSGQGRSSRGGQQGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASSGQQGSHYSQSSSYGTHNSGGSPSSSQRGHGSRSGRSSGLGQYGSPSGQTSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQPTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRCGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTSGRSQHQSGSRHGSGSGQFPISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSGLGHYGSTSGQTASSTRQGSGQGQASGSGRCGASSGQTSGCGSDQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRFGSGSGGSSGFSQGRSGQGRSSRGGQQGSFSGQTEGSQQHGSCCGQSSGYGQNEYGSGHSASSGQQGSHYSQSSSYGTHNSGGSPSSSQRGHGSRSGRSSGLGQYGSPSGQTSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTSGRSQHQSGSRHGSGSGQFPISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSGLGHYGSTSGQTASSTRQGSGQGQASGSGRCGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTSGRSQHQSGSRHGSGSGQFPISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSGLGQYGSPSGQTSSSTRQGSGQGQASGSGRYGASSGQTSGCGSGQSTRYGEQGSGSRNSSTQSRGRSTSRESSTSQRYGSGSGESSGFSQGGSGQGRSSRGGQQGSFSGQTSGRSQHQSGSRHGSGSGQFPISGQQGSHHGHSSSSGTHNSGSSQSSSTQWSHGSGSEQSSGLGHYGSTSGQTASSTRQGSGQGQASGSGRCGASSGQTSGCGSG
Protein: Desmethyl-yatein O-methyltransferase (EC 2.1.1.330) (A0A0N9HTA1)
Organism: Sinopodophyllum hexandrum (Himalayan may apple) (Podophyllum hexandrum)
Function: O-methyltransferase involved in the biosynthesis of etoposide, a chemotherapeutic compound of the topoisomerase inhibitor family. Catalyzes the methylation of (-)-5'-demethylyatein to produce (-)-yatein.
Interaction partners:
Sequence:
MDTRADAEIKAMELIGIGVLPLAMKAIIELNVLEILSKAGPDTQLTAAQIVTDIPTTNPNAGFQLDRILRLLASHSVLSSSITKSGERVYGLTPMCKYFLPDQDGVSLAPMVVTIHDKVLLQSWHYLKDSVLKQGSLPFTEAFGMSPFEYSVSDTRFNKVFNAGMFDHSTLCMRDVLQRYKGFQGLGELVDVGGGTGGSLKMILSQYPNLKGINFDLPHVVADAPSFPGVKHIGGDMFESVPSGDAIFMKWILHDWDDGRCLTLLKNCWNALPEHGKVIIVEWILPSDAATDPTSRRVFTADLMMLAFSEGGKERTLGDYGALAKEAGFTTVKDFPCANGISVIEFHKK
Protein: Uncharacterized protein C23C11.07 (O13913)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Interaction partners:
Sequence:
MASHFLFTGKPWLQEKTPRLHLHPTWDLKASKSLARFPYTPLESLLAPISAFHPTYLNSAAPSKAQSHPVLLAAGVGGIVVRCPSRKPIYRTTRIQYLLLISHFTTALFK
Protein: tRNA dimethylallyltransferase (EC 2.5.1.75) (Q8I0X4)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
- GTP-binding protein, putative
- Pseudouridylate synthase, putative
- Putative tRNA
- Threonylcarbamoyladenosine tRNA methylthiotransferase
- Putative tRNA-specific 2-thiouridylase
Sequence:
MPFNKYVLLIYFILLVNINLFKKKKFNTSTRVGNCFMIYDKNIKLNKIEDIKKNNILQKEKRVFNNIILLRTNIDKKKKNLLKLLYNSSKLKTTGCQRKYKNRKCYSYLINNRRINTVECLRKVLNKSNYKIVSKLFKKNNVKTYMSNSNIDDSDIINLLKLNGKEKNMDNSKIGKCINTKNEEGDDELMSHKMNDMINYLNEDPMKIMNPLDITQLNFFRDGNSQKKEKIIIIIGVTCSGKTKFSIDLSEQLMKYKIKSEIISADSMQVYQNFNVGIAKVEEEEMKDVKHHLLDVCHPNDTFNAHKYINYTIPLIKNMNRNNKIPIIAGGTLLYIESLLWESVIDIRKEEEKKEQTYNGQIIKKEDEYLDEHLKLNNDIKCNGERNDDMVELDKYEHKTNEELYEELKNIDEERANQLHKNDRKRVCRSLDIFYTYNKKHSDLIKIKNHKNNNIDKMRFFPCIFYLDYNDDDLLKMKIKNRVDLMISKGLLDEAIKLKQINNDRKLSFPTKGINQSIAYKEFDEYIKKKMDNIDDQKLFEKCKDNLIRRTYKYAKKQRRWISNRFVKVYNVELNKIDVSNNYEKQLNNAIGIVLKFLKCQ
Protein: Inner kinetochore subunit MHF1 (CENP-S homolog) (Constitutive centromere-associated network protein MHF1) (MHF histone-fold complex subunit 1) (MPH1-associated histone-fold protein 1) (Q3E835)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: dsDNA-binding component of a FANCM-MHF complex involved in DNA damage repair and genome maintenance. FANCM-MHF promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork (By similarity). Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.
Interaction partners:
- Inner kinetochore subunit MHF2
- ATP-dependent DNA helicase MPH1
- Histone H3
- Histone H3-like centromeric protein CSE4
- Protein SCM3
- Uncharacterized protein YGR042W
- ATP-dependent DNA helicase SRS2
- Spindle assembly checkpoint serine/threonine-protein kinase BUB1
Sequence:
MNDDEDRAQLKARLWIRVEERLQQVLSSEDIKYTPRFINSLLELAYLQLGEMGSDLQAFARHAGRGVVNKSDLMLYLRKQPDLQERVTQE
Protein: Large ribosomal subunit protein eL8 (60S ribosomal protein L7a) (Q966C6)
Organism: Caenorhabditis elegans
Interaction partners:
- Large ribosomal subunit protein eL18
- Ubiquitin-like domain-containing protein
- Large ribosomal subunit protein eL24
- Small ribosomal subunit protein eS6
- Small ribosomal subunit protein eS17
- Small ribosomal subunit protein uS15
- Large ribosomal subunit protein uL4
- Small ribosomal subunit protein uS9
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein eS4
Sequence:
MPSKKVIKKKVAAVPAHIRAQTQVQKEVKNPLFEKRARNFNIGQDIQPKKDVTRFVKWPKYIRLQRQSAILQKRLKVPPTINQFRTALDSQSARQAFKLLDKYRPESTEAKKNRLRARAEARAAGKKEEVTKRPNTVRHGVNTITRLVETRRAQLVLIAHDVNPLEIVLHLPALCRKYNVPYAIIKGKASLGTVVRRKTTAAVALVDVNPEDKSALNKLVETVNNNFSERHEEIRKHWGGGVMSAKSDAKKLKIERARARDLGKL
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q9VI84)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Serine/threonine-protein kinase RIO1
- Doublecortin-like and CAM kinase-like protein
Sequence:
MQSIGWTLIMKRGCLFSCRKETLNINGSRYTIRERLATGGFSLIDLGENASTRRSYAIKRITCHSIDDQNIALREIENCRKIDSENVIRVVDYELKGQADIVINTTSTLFIVLPYYKHGSLADHLQLRSRKQDHMPEAQILQIFLGVCEGLKAIHEAMPVPLAHRDLKTANICLSDSFEPIIVDLGSMTEARLQIVGQTDAQRLQDEAEERSSIVYRAPELFTVKTYCTIDERTDIWSLGCVLYAMCYFNSPYDPIYERGDSVALAVLSGNINIPEDSIYTEDMHELIKYMLRTDPMERPFVFSVIERTHDLIQKLEGRL
Protein: KAR9-domain-containing protein (Q5BBH9)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Uncharacterized protein
Sequence:
MRAIFTTSSHPSAPAPDTSTSATTSQGSPPPPPPPLVSVSSPDESATPRRIKSKASLRSTRSIGSSLLHEDDGDDAQSEKSLIRPNILRRLSPGLAARVKLLDGSSKTATSPRNPGAVGRIPEEQIKELDSLHKVQSIEVERKGRAWSGISFANKTQKQQVQREPLPQSGVPEPPVAESTPGSGQDATSDRLETKEEKVENTPTTMSVVEPAPAPLGPEISDPNIEDQTDGPTDYEKYIQKTSELEAEANGAPRPPPKDSPPIQSSASSNTQSYFNPHGLHRTSSIYSSTNSIFSFSRSSFSNQISQLTSIALPQPSSLEASIASISNAPAAVKALTGAAEQIQIWIRKASNVLNGLDAEDDVVWAAAAGREGLDGVDKAITKFESLVNVYVKAIEDVQLREDIANVSTDGLETIVTQMDSILQSWANIKSRLRAVKEQVELAMEWEELWNSVLGDVGEEVEELEGLVFEMEAKRHFNLANEDSTGLDINELETIVEETPSSGRFLNKRSSMGSLYPAPPALDRPIIQTPQDDTNHSNLVELFARLQPLRASLDFLPMRLSMFQSRAEKVFPSACTELMERREKLEKDYKNLQADAETLRKELEEDRWIMVFRNAGSQAQKMFESVERSISKLQEGLETGMHLHNPAGMTNRIESYEAKKQHYVPAIDRVLTITQKGVKDRLTVNGEILRLLANMESQVNALRASIKVMDSSLEDIQDLRSQHMRDSISTVLTIDSPATGSLADTPGSSPASSVVMTPANKSSRRGSSVGSAARTSTGRRVSGLPQLASNLTGRKPSNPKATPKTTLTAPSPTPAARKPAQPAQPALSPALLNRPRWNTSTNTNDLDVGHKYKPWTPSLRKQTAPSRGTRPSSTIPPRDPSTSPVPPTARSASRISSRLGLRSPGRTASPSPSPSILDPPPYSKLRRPAGTENMSNTPRSRQSFAGTSFNRSVSQEQGRSDSPTKAARPGTALGHSGSRRISLLPLPRNRNKDNFPSTRSKLSERPPWRG
Protein: Pre-mRNA-splicing factor cwf12 (Complexed with cdc5 protein 12) (O74370)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in pre-mRNA splicing and cell cycle control.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P21374}. Nucleus {ECO:0000250|UniProtKB:P21374}.
Interaction partners:
- Pre-mRNA-processing factor 17
- Pre-mRNA-splicing factor cwf3
- Pre-mRNA-processing factor 19
- Pre-mRNA-splicing factor cdc5
- Pre-mRNA-splicing factor cwf10
- Pre-mRNA-splicing factor syf2
- Pre-mRNA-splicing factor cwf2
- Pre-mRNA-splicing factor cwf14
- Pre-mRNA-splicing factor spp42
- Pre-mRNA-splicing factor cwf4
Sequence:
MSSAKYVVGSKPTEKRPKDIKSIKSVPICEKHRASVVKDISRKISRIQSATLPEYQIRDLNDAINRLMREKHEWEVQIRDLGGINYLYNKAKLFEDEGEQISDIDDYRYYGRARELPGVKELFEADMSFIPERQRKQEMQKRRLDAWYFGYIPPAQESLLEDFEAKIEEQQHKHLENLGDEVEQDWKPLVIEQIPTRDDVEAILLERRKNALLSRIS
Protein: Polyamine deacetylase HDAC10 (EC 3.5.1.48) (EC 3.5.1.62) (Histone deacetylase 10) (F1QCV2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Polyamine deacetylase (PDAC), which acts preferentially on N(8)-acetylspermidine, and also on acetylcadaverine and acetylputrescine. Exhibits attenuated catalytic activity toward N(1),N(8)-diacetylspermidine and very low activity, if any, toward N(1)-acetylspermidine. Has a very weak lysine deacetylase, if any.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q969S8}. Nucleus {ECO:0000250|UniProtKB:Q969S8}. Note=Excluded from the nucleoli. {ECO:0000250|UniProtKB:Q969S8}.
Interaction partners:
- Nuclear receptor corepressor 2
- AT-rich interactive domain-containing protein 4B
- AT-rich interactive domain-containing protein 4A
- UPF0489 protein C5orf22 homolog
- Histone deacetylase 1
- protein acetyllysine N-acetyltransferase
Sequence:
MASGSALIFDEEMSRYKLLWTDPACEIEVPERLTVSYEALRTHGLAQRCKAVPVRQATEQEILLAHSEEYLEAVKQTPGMNVEELMAFSKKYNDVYFHQNIYHCAKLAAGATLQLVDSVMKREVRNGMALVRPPGHHSQRSAANGFCVFNNVAIAALYAKKNYNLNRILIVDWDVHHGQGIQYCFEEDPSVLYFSWHRYEHQSFWPNLPESDYSSVGKGKGSGFNINLPWNKVGMTNSDYLAAFFHVLLPVAYEFDPELVIVSAGFDSAIGDPEGEMCALPEIFAHLTHLLMPLAAGKMCVVLEGGYNLTSLGQSVCQTVHSLLGDPTPRISGLGTACDSALESIQNVRNVQSSYWSSFKHLAQSETNPKRPRLDATNGGPKESSEPASESNPKKTAQDIVWPEPLKRMPASVRTVVVPPPGVELTLPKNCQHSGDISESTAKEVQRIRDKHFHDLTDQNILRSLGNIISVLDRMMRSDEVCNGCVVVSDLSVSVQCALQHALTEPAERVLVVYVGDGELPVKTNDGKVFLVQICTKETEDKCVNRLSLCLREGESLTAGFMQALLGLILPVAYEFNPALVLGIVGETAAKTGLMTVWGHMTCLIQGLARGRTLTLLQGYDKDLLELTVSALSGASISPLGPLRALKPEDVEMMEKQRQRLQERWGLLRCTVSES
Protein: Protein mtd-1 (Mec three-dependent expression protein 1) (G5ECI1)
Organism: Caenorhabditis elegans
Function: Plays a role in mechanosensory transduction (touch sensitivity).
Subcellular location: Cell membrane {ECO:0000269|PubMed:12385749}; Single-pass type I membrane protein {ECO:0000255}; Extracellular side {ECO:0000305|PubMed:12385749}.
Interaction partners:
- AMP-binding domain-containing protein
Sequence:
MRSSLLLLVFFLSIGWARYCVHNEKSWCQGHNIWGWCFHNKSSGVFNCDDNAFCVSQEQLKNKKSSGCFLRDNSSICCCNDADGCNLGFIGVQPKYAHGQQCTNSMEVPNEDIRQFRPCDDPFCYSVLTAEDDGGPTTVTRGCHSRKMVMHHMSKNEDDKYQNNTKWRETKQIAEMPSCAEILKDQPKVNGTTSMCVDFTYDQEAEDGEEVDEPIKMKGRLCCCAGSNKCNEHAMWADEGISLTEMLEEIEARKVPVDSSAPVNIILSIAFSIFLIHF
Protein: Bidirectional sugar transporter SWEET14 (AtSWEET14) (Protein SUGARS WILL EVENTUALLY BE EXPORTED TRANSPORTERS 14) (Q9SW25)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MVLTHNVLAVTFGVLGNIISFIVFLAPVPTFVRICKKKSIEGFESLPYVSALFSAMLWIYYALQKDGAGFLLITINAVGCFIETIYIILFITYANKKARISTLKVLGLLNFLGFAAIILVCELLTKGSNREKVLGGICVGFSVCVFAAPLSIMRVVIRTKSVEFMPFSLSLFLTISAITWLFYGLAIKDFYVALPNILGAFLGAVQMILYVIFKYYKTPLVVDETEKPKTVSDHSINMVKLSSTPASGDLTVQPQTNPDVSHPIKTHGGDLEDQMDKKMPN
Protein: Small ribosomal subunit protein eS1 (40S ribosomal protein S3a) (Q54ZW5)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03122}.
Interaction partners:
- Large ribosomal subunit protein eL38
- Small ribosomal subunit protein uS13
- Large ribosomal subunit protein eL27
- Small ribosomal subunit protein eS4
- Small ribosomal subunit protein eS10
- Small ribosomal subunit protein eS24
- Large ribosomal subunit protein eL15
- Large ribosomal subunit protein eL29
- Small ribosomal subunit protein eS26
- Small ribosomal subunit protein eS7
Sequence:
MADKKKKGSKKGGKKVDPFTRKEWYVVRAPTQFFKSPADNKVGFTPVNRTQGTKLASDGLKGRVYEVSLADMKDDESQVFRKIKLRAEEVEGRNVLTNFYGMDLTSDKLRSLIHKWSTLIECFVDVKTTDGYFLRVFAICFTKKGESQKKKTSYAKTSRVKAIRKKMVDILTETVSSNDLKTVVDYLIGVSLNGVTTNASGFAPTLAEKIRIEGSSIFPIHNVFIRKVKVLKTPKVDAAKLSELYASSATSTIAPTEEVGTAVERTEETTTTA
Protein: Transcription factor Sox-14 (SRY (sex determining region Y)-box 14) (B0ZTE2)
Organism: Xenopus laevis (African clawed frog)
Function: Acts as a negative regulator of transcription (By similarity). May function as a switch in neuronal development.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9W7R6, ECO:0000255|PROSITE-ProRule:PRU00267}.
Interaction partners:
Sequence:
MSKPVDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYVFPLPYFGDHDPLKTGLSMSATDSILGASEKARAFFPPTSTPYSLLDPSHFSSTTIQKMTEMPHTLATSTLPYASTLGYQNGAFGGLSCPSQHTHTHPSPTNPGYVVPCNCTAWSASNLQPPVAYILFPGMTKAGIDPYSSAHTTAM
Protein: TBC1 domain family member 4 (A0A3B3IRT3)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MKEDAKPSKDNEDAFYNSQKFEVLYCGKVTVTHKKAPSSLIDDCMEKFSLHEQQRLKIQGEQRGPDPGEDLADLEVVVPGSPGDCLPEEADGTDTHLGLPAGASQPALTSSRVCFPERILEDSGFDEQQEFRSRCSSVTGVQRRVHEGSQKSQPRRRHASAPSHVQPSDSEKNRTMLFQVGRFEINLISPDTKSVVLEKNFKDISSCSQGIKHVDHFGFICRESPEPGLSQYICYVFQCASESLVDEVMLTLKQAFSTAAALQSAKTQIKLCEACPMHSLHKLCERIEGLYPPRAKLVIQRHLSSLTDNEQADIFERVQKMKPVSDQEENELVILHLRQLCEAKQKTHVHIGEGPSTISNSTIPENATSSGRFKLDILKNKAKRSLTSSLENIFSRGANRMRGRLGSVDSFERSNSLASEKDYSPGDSPPGTPPASPPSSAWQTFPEEDSDSPQFRRRAHTFSHPPSSTKRKLNLQDGRAQGVRSPLLRQSSSEQCSDGEGRKRTSSTCSNESLSVGGTSVTPRRISWRQRIFLRVASPMNKSPSAMQQQDGLDRNELLPLSPLSPTMEEEPLVVFLSGEDDPEKIEERKKSKELRSLWRKAIHQQILLLRMEKENQKLEASRDELQSRKVKLDYEEVGACQKEVLITWDKKLLNCRAKIRCDMEDIHTLLKEGVPKSRRGEIWQFLALQYRLRHRLPNKQQPPDISYKELLKQLTAQQHAILVDLGRTFPTHPYFSVQLGPGQLSLFNLLKAYSLLDKEVGYCQGISFVAGVLLLHMSEEQAFEMLKFLMYDLGFRKQYRPDMMSLQIQMYQLSRLLHDYHRDLYNHLEENEISPSLYAAPWFLTLFASQFSLGFVARVFDIIFLQGTEVIFKVALSLLSSQETLIMECESFENIVEFLKNTLPDMNTSEMEKIITQVFEMDISKQLHAYEVEYHVLQDELQESSYSCEDSETLEKLERANSQLKRQNMDLLEKLQVAHTKIQALESNLENLLTRETKMKSLIRTLEQEKMAYQKTVEQLRKLLPADALVNCDLLLRDLNCNPNNKAKIGNKP
Protein: ADP/ATP translocase (ADP,ATP carrier protein) (Q5A516)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane {ECO:0000256|RuleBase:RU368008}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU368008}. Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004448}.
Interaction partners:
- ATP synthase subunit beta
- ATP synthase subunit alpha
- I-AAA protease
- Cytochrome b-c1 complex reductase subunit, mitochondrial
- Mitochondrial thiamine pyrophosphate carrier 1
Sequence:
MVDSNFFVDFMMGGVSAAVSKTAAAPIERVKLLIQNQDEMIKQGRLEKRYTGIVDCFKRTAADEGVVSFWRGNTANVIRYFPTQALNFAFKDKFKAMFGFKKDENYWKWFAGNLASGGLAGATSLAFVYSLDYARTRLANDAKSSKGDGKREFNGLVDVYKKTLASDGIAGLYRGFGPSVIGIVVYRGLYFGLYDSLKPVVLVGPLEGSFLASFLLGWAVTTGASTASYPLDTVRRRMMMTSGQAVKYDGALDCFRKVVAAEGVGSLFKGCGANILRGVAGAGVISLYDQLQVILFGKKFK
Protein: High-affinity nickel transport protein nic1 (O74869)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: High-affinity nickel transporter responsible for nickel uptake. Required for urease biosynthesis.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Urease
- Uncharacterized urease accessory protein UreF-like
- Uncharacterized urease accessory protein ureG-like
- Arginase
Sequence:
MNSMSEYVKPRKNEFLRKFENFYFEIPFLSKLPPKVSVPIFSLISVNIVVWIVAAIVISLVNRSLFLSVLLSWTLGLRHALDADHITAIDNLTRRLLSTDKPMSTVGTWFSIGHSTVVLITCIVVAATSSKFADRWNNFQTIGGIIGTSVSMGLLLLLAIGNTVLLVRLSYWLWMYRKSGVTKDEGVTGFLARKMQRLFRLVDSPWKIYVLGFVFGLGFDTSTEVSLLGIATLQALKGTSIWAILLFPIVFLVGMCLVDTTDGALMYYAYSYSSGETNPYFSRLYYSIILTFVSVIAAFTIGIIQMLMLIISVHPMESTFWNGLNRLSDNYEIVGGCICGAFVLAGLFGISMHNYFKKKFTPPVQVGNDREDEVLEKNKELENVSKNSISVQISESEKVSYDTVDSKV
Protein: Tumor suppressor candidate 2 (Fusion 1 protein) (Fus-1 protein) (PDGFA-associated protein 2) (Q9WVF8)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MGASGSKARGLWPFASTPGGGGPEAAGSEQSLVRSRARAVPPFVFTRRGSMFYDEDGDLAHEFYEETIVTKNGQKRAKLRRVHKNLIPQGIVKLDPPRIHVDFPVILYEV
Protein: U6 snRNA-associated Sm-like protein LSm2 (Q9VTW6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- U6 snRNA-associated Sm-like protein LSm6
- U6 snRNA-associated Sm-like protein LSm7
- U6 snRNA-associated Sm-like protein LSm8
- U6 snRNA-associated Sm-like protein LSm4
- U6 snRNA-associated Sm-like protein LSm5
- Probable small nuclear ribonucleoprotein Sm D2
- U6 snRNA-associated Sm-like protein LSm1
- U6 snRNA-associated Sm-like protein LSm3
- Protein associated with topo II related - 1, isoform A
- Small nuclear ribonucleoprotein F
Sequence:
MLFYSFFKSLVGKEVVVELKNDLSICGTLHSVDQYLNIKLTDISVTDPDKYPHMLSVKNCFIRGSVVRYVQLPGDEVDTQLLQDAARKEAVVSTR
Protein: CUB-like domain-containing protein (O02358)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MLCQVSALVFLVTLNVVAAQFSCPTTHITKDNGIFGAIPTGAASMVTVPAGVDCTYFFDIPKGFAVKLETTALYDVSPGDSIRFDYFYISSPAEKRIEFAVNQTLPFHVVSVTGNLQFFATYTYIDMTGYQQVVQPTGTFFNSTLEANKYLTFKSAENEQVAVKYGSLQSGFADSSIYEIFVFDGNDITNAEYLGRFTELYHAPQYAIYSTSNTLTFLNLYRTPSNSMLLANDASVIENYEVYNIMVLDSVNPYSGYMSNYYDDADAYFTVICDGCSSINIKTLIFDSKYKNGAGYLEVAEMSPTQKLPAKLNYPASTSPSNRLPQLISSQMATFHTFNARVTYGIQGVN
Protein: Copper transporter 1 (OsCOPT1) (Q94EE4)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Involved in the transport of copper, in cooperation with SWEET11 and COPT2. Contributes to the removal of copper (Cu) from xylem, and thus to the sensitivity toward bacterial pathogens such as X.oryzae pv. oryzae (Xoo).
Subcellular location: Cell membrane {ECO:0000269|PubMed:20852017}; Multi-pass membrane protein {ECO:0000269|PubMed:20852017}.
Interaction partners:
Sequence:
MDMGGHDMGGMSPPAAGAAAQGGMGAMKSMRYTHMTFFWGKNSEVLFTMWPGTRGGMYALALIFVFALAVIVEFLGSRRADACLAALARRAPAAGGLARAAVHTVRVGVAYLLMLALMSFNGGVFLVAVAGHAAGFLAFRAGLCGGPAQVEEDRKNDPACC