wanglab/gogpt-training-data huggingface dataset:
Protein: Transient receptor potential cation channel, subfamily M, member 5 (A0A8I6AG64)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MPGVRKVTMPMAQSSCPGSPPDTGDGWEPVLCKGEVNFGGSGKKRSKFVKVPSNVAPSMLFELLLTEWHLPAPNLVVSLVGEERLFAMKSWLRDVLRKGLVKAAQSTGAWILTSALHVGLARHVGQAVRDHSLASTSTKVRVVAIGMASLDRILHRQLLDGVQEDTPIHYPADEGSTQGPLCPLDSNLSHFILVEPGTLGSGNDGLAELQLSLEKHISQQRTGYGGTSSIQIPVLCLLVNGDPSTLERMSRAVEQAAPWLILAGSGGIADVLAALVGQPHLLVPQVTEKQFREKFPSECFSWEAIVHWTELLQNIAAHPHLLTVYDFEQEGSEDLDTVILKALVKACKSHSRDAQDYLDELKLAVAWDRVDIAKSEIFNGDVEWKSCDLEEVMTDALVSNKPDFVRLFVDSGADMAEFLTYGRLQQLYHSVSPKSLLFELLERKHEEGRLTLAGLGAQQTRELPVGLPAFSLHEVSRVLKDFLHDACRGFYQDGRRMEERGPPKRPAGQKWLPDLSRKSEDPWRDLFLWAVLQNRYEMATYFWAMGREGVAAALAACKIIKEMSHLEKEAEVARTMREAKYEQLALDLFSECYSNSEDRAFALLVRRNHSWSRTTCLHLATEADAKAFFAHDGVQAFLTKIWWGDMATGTPILRLLGAFTCPALIYTNLISFSEDAPQRMDLEDLQEPDSLDMEKSFLCSHGGQLEKLTEAPRAPGDLGPQAAFLLTRWRKFWGAPVTVFLGNVVMYFAFLFLFSYVLLVDFRPPPQGPSGSEVTLYFWVFTLVLEEIRQGFFTNEDTRLVKKFTLYVEDNWNKCDMVAIFLFIVGVTCRMVPSVFEAGRTVLAIDFMVFTLRLIHIFAIHKQLGPKIIIVERMMKDVFFFLFFLSVWLVAYGVTTQALLHPHDGRLEWIFRRVLYRPYLQIFGQIPLDEIDEARVNCSLHPLLLDSSASCPNLYANWLVILLLVTFLLVTNVLLMNLLIAMFSYTFQVVQGNADMFWKFQRYHLIVEYHGRPALAPPFILLSHLSLVLKQVFRKEAQHKQQHLERDLPDPVDQKIITWETVQKENFLSTMEKRRRDSEEEVLRKTAHRVDLIAKYIGGLREQEKRIKCLESQANYCMLLLSSMTDTLAPGGTYSSSQNCGRRSQPASARDREYLEAGLPHSDT
Protein: Protein methyltransferase (C8VIM6)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Small ribosomal subunit protein uS5
- rRNA 2'-O-methyltransferase fibrillarin
- Histone H4.1
- Histone H4.2
- Uncharacterized protein
- ATP-dependent RNA helicase dbp3
- Histone H2A
Sequence:
MSAPSAAERPLKDIDRDSLASEDSDATDEEGWEDVEPDDETQPVVGLFSDKVYPDVRSMLKESKDKHDFDLRKLQKELDLDFLDTIKLVNYIRSSVKKGNMTPDLSSKDKFQSEIYLKPVLEDDALLYSLDDIEDEEPGEAVGETQAERQVVELQEELERLQIQFSEYRLAVQKSLEEQLTKEDEKLPLTPAGRTSTKAEEVDSDYFTSYAYNGIHESMLKDTIRTDSYRDFVYENKHIFKDKVVLDVGCGTGILSMFCAKAGARKVISVDNSNIIDRAKEIVYENGFGDVITCIRGKIEEVTLPVEQVDIIISEWMGYGLLFEAMFDSVIYARDRYLAPGGLMAPSHATLRIAPLADPDLVQSHIGFWHDVYGFNMKSMLTGIYDEALVRTVPSSVIAAESQIFLTLPLHTITVEELSFLKEFELTLKEDVDALDGWAIWFDIFFMPSRDSTLPPNATPADLQKKGIVSFTTGPDGKETHWQQTILLIDHGKKHAAPLKKGQLIKGKVGYQKKDSNSRSLNITVEYDAGVGERGSQNWALQ
Protein: Aquaporin-5 (AQP-5) (P47864)
Organism: Rattus norvegicus (Rat)
Function: Forms a water-specific channel. Plays an important role in fluid secretion in salivary glands. Required for TRPV4 activation by hypotonicity. Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells. Seems to play a redundant role in water transport in the eye, lung and in sweat glands (By similarity).
Subcellular location: Apical cell membrane {ECO:0000250|UniProtKB:Q9WTY4}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P55064}. Cell membrane {ECO:0000269|PubMed:7530250}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P55064}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:P55064}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P55064}. Note=Hypotonicity increases location at the cell membrane. Phosphorylation decreases location at the cell membrane. {ECO:0000250|UniProtKB:P55064}.
Interaction partners:
- Aquaporin
- Surfactant protein C
- Aquaporin-11
- Uteroglobin
- Pulmonary surfactant-associated protein B
- Aquaporin-7
- Keratin, type II cytoskeletal 5
- Aquaporin-3
Sequence:
MKKEVCSLAFFKAVFAEFLATLIFVFFGLGSALKWPSALPTILQISIAFGLAIGTLAQALGPVSGGHINPAITLALLIGNQISLLRAVFYVAAQLVGAIAGAGILYWLAPLNARGNLAVNALNNNTTPGKAMVVELILTFQLALCIFSSTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPSHWVFWVGPIVGAMLAAILYFYLLFPSSLSLHDRVAVVKGTYEPEEDWEDHREERKKTIELTAH
Protein: Polo-like kinase (C8VMZ9)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- M-phase inducer phosphatase
- Protein kinase domain-containing protein
- Separin
- Double-strand-break repair protein rad21
- Chromosome segregation protein sudA
- Tyrosine-protein phosphatase cdcA
- GTP binding protein
- Mitotic check point protein
- Uncharacterized protein
- Protein phosphatase PP2A regulatory subunit B
Sequence:
MERHLQPTMEALSPRSTNQMIKPKASMERKVLDKNAAAAQKASSAKNHAPPPPALVVEPGDDGEQYSTGAFLGKGGFAICYEGTLLRNGRVFAMKVVKSDMGQKKMQEKFRTELQIHSKMRHPHIVGFHRAFVYDQCIYVILELCPNGSVMDMVRKRKCLSLPEVRRFMVQLCGAVKYLHKRNVAHRDLKMGNLFLDRNMDIKVGDFGLAAMIMSEKDEKRRKTLCGTPNYIAPEVLDRSKGGHTQKVDIWSLGVICFAMLTGYPPFQSKTQEEIYKKVRNLTYVWPKDSECANHIPDEAKSLVSCCLNLDEQKRPEPDDIVEHAFFNMYNGCIPKRLDPKCSVQKPTWLRGAEPQGDAMAFGHGLDFDEKFSSYIRDVDDPILRYRTCKAAFYSSCGVGRKPDGTARKSVGHNASKSGFAECLAEEEKGLQPLMPLPEDMVYKYPHDLIGDWSVPESLPLRRQDALADTSVLSSRSSSTSLRTNTVSQSRTQAALAAAQQRRNGSQSHAASLRQQALTGRGTIRKIPSLCDPPQPTMKAMPDVRDAGLNPDPVPPVPTGGLAERPIRTRRGIAASYSGTTSVRGMDTNAVPSVSQASNDLGMLTVGKTRSQSRKLEAANQVAVEPLRVLKDRSTSTGPENLAAVSRQKSARTVHKDLGGVAARKPDSEAARREEPVTRQRTEAQPQPMSSSGSKASLSSTNKPRSSLGLHALLHSDDPCELLPGSSIDDVKIDLRNMLSNLVPGSAARRRVVSQRPPHAYVIKWVDYTNRYGIGYVLDDGSVGCVFKAENGQPASGVVLRDGEKHIRRKARSQENSDSQSWSYSEADQLVPRHGKPVEFYENCSDDLLECRGGICRALIPPSLFEVKDSSGGVKVRMDSGISRARADAEKIKRVKLVDQFGKYMIGSLGRHGDETLLDDAATDGAPGQFIKFYQRLGNVGVWGFGDGAFQFNFPDHTKLVLAPGRTRNSSPWMDFYHLSPTAARYLAAKGKMHPSGFDTRAVVSDEIATFLSIAYGTSTSAMDDKIREVLDANSFLQKIAFIKDVLKSWIRQGRLGGRPSSDKPGTEMFWEGSQERPQASGGGSSKFVWVTVGAPGGDGEYRSVSLRDKKGNSVGENDEMEALRERLRLAGL
Protein: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (PGMi) (TbiPGAM) (iPGAM) (EC 5.4.2.12) (Phosphoglycerate mutase) (Q38AH1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Catalyzes the interconversion of 2-phosphoglycerate (2-PGA) and 3-phosphoglycerate (3-PGA).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21993954}.
Interaction partners:
- phosphopyruvate hydratase
- Enolase, putative
- Phosphoglycerate kinase
- Phosphoglycerate kinase
- Phosphoglycerate kinase
- C3H1-type domain-containing protein
- Cleavage and polyadenylation specificity factor-like protein, putative
- Cleavage stimulation factor 50 kDa subunit
- Cleavage and polyadenylation specificity factor 30 kDa subunit
- Glucose-6-phosphate isomerase
Sequence:
MALTLAAHKTLPRRKLVLVVLDGVGIGPRDEYDAVHVAKTPLMDALFNDPKHFRSICAHGTAVGLPTDADMGNSEVGHNALGAGRVVLQGASLVDDALESGEIFTSEGYRYLHGAFSQPGRTLHLIGLLSDGGVHSRDNQVYQILKHAGANGAKRIRVHALYDGRDVPDKTSFKFTDELEEVLAKLREGGCDARIASGGGRMFVTMDRYEADWSIVERGWRAQVLGEGRAFKSAREALTKFREEDANISDQYYPPFVIAGDDGRPIGTIEDGDAVLCFNFRGDRVIEMSRAFEEEEFDKFNRVRLPKVRYAGMMRYDGDLGIPNNFLVPPPKLTRTSEEYLIGSGCNIFALSETQKFGHVTYFWNGNRSGKLSEERETFCEIPSDRVQFNQKPLMKSKEITDAAVDAIKSGKYDMIRINYPNGDMVGHTGDLKATITSLEAVDQSLQRLKEAVDSVNGVFLITADHGNSDDMVQRDKKGKPVRDAEGNLMPLTSHTLAPVPVFIGGAGLDPRVQMRTDLPRAGLANVTATFINLMGFEAPSDYEPSLIEVA
Protein: Serine/threonine-protein phosphatase 2B catalytic subunit A1 (EC 3.1.3.16) (Calcineurin A1) (O42773)
Organism: Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)
Function: Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin (By similarity).
Interaction partners:
Sequence:
MASPATQTANAIAAINNRSNLVIPEIDFTQHQLENGEIVSTTERVIKDVQAPAMYVPTDDQFWSKVDKTKPDIAFLKNHFYREGRLTEEQALYILEKGGELLRSEPNLLEVDAPITVCGDIHGQYYDLMKLFEVGGNPADTRYLFLGDYVDRGYFSIECVLYLWSLKMWYPDTLFLLRGNHECRHLTDYFTFKLECKHKYSETVYNACMESFCNLPLAAVMNKQFLCIHGGLSPELHTLDDLRSINRFREPPTQGLMCDILWADPLEDFGSEKTNENFLHNHVRGCSYFFTYNAACQFLERNNLLSIIRAHEAQDAGYRMYRKTKTTGFPSVMTIFSAPNYLDVYSNKAAVLKYESNVMNIRQFNCTPHPYWLPNFMDVFTWSLPFVGEKITDMLIAILNCCTKEELEEEDEEFPLNAPEPTDAESAAERRQIIKNKILAVGRMSRVFSLLREESERVSELKSISGSNALPAGMLASGAEGIKEAIQGFEDARKSDIENERLPPDIIDPDEDKPASPSASPIMPATPEEIPSEIPYDSPITGTPRTPISSAIASGSPGSPGTPTSPSIGGPPLTAWRPGHGRRTSLGTTKTSPSTRRRSLENTMHLIRDVVGGKDAQGDGQLERLAEVISSPTKGGQGE
Protein: Lectin (Agglutinin) (BMA) [Cleaved into: Lectin beta chain; Lectin alpha chain] (P42088)
Organism: Leucomphalos mildbraedii (Bowringia mildbraedii)
Function: Binds preferentially to oligosaccharides bearing the sequence Man-alpha-1->2 Man-alpha-1->6 Man-alpha-1->6Man found in early steps of glycoprotein processing in the endoplasmic reticulum. It binds weakly to highly processed oligosaccharide structures.
Interaction partners:
Sequence:
ANSVCFTFTDFESGQQDLIFQGDASVGSNKALQLTKVDSKGNPQGGSVGRALYTAPIRLWQSSSLVASFETTFTFSISQGSSTPAAALTFFIASPDTKIPSGSGGRLLGLFGSSNNAGSDNGVVAVEFDTYPNTDIGDPNYRHIGIDVNSIRSKAASKWDWQNGKTATAHISYNSASKRLSVVSSYPNSSPVVVSFDVELNNVGPPDVRVGFSATTGQYTQTNNILAWSFRSSLMGYQAN
Protein: Kinesin-like protein 6 (O59751)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has a role in establishing metaphase during mitosis. Required for chromosome segregation where it generates tension during kinetochore capturing.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11967147}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11967147}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:11967147}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:11967147}. Note=Cytoplasmic microtubules in interphase, mitotic kinetochores in metaphase and spindle midzone in anaphase and telophase.
Interaction partners:
- Kinesin-like protein 5
- Anaphase spindle elongation protein 1
- Spindle pole body component alp14
- Phosphoprotein p93
- Kinesin-like protein 2
- Microtubule integrity protein mal3
- Tubulin alpha-2 chain
- Kinesin-like protein cut7
- Tip elongation protein 1
- Microtubule protein alp7
Sequence:
MKEGSSISVAVRVRPFTEREKGLLAETPKSKEFLGDGSLAVSNTSSNTFCTNGIRKIVRVLDDNVLIFDPPEENPLAKVQKSLLPAGKRFRDVRYAFDRLFGEEASQEDVYKGTTEPLLDSVLQGYNATVFAYGATGCGKTHTISGRPDDPGIIFLTMRALLDRVEGLKRTMNVDISVSYLEIYNEKIRDLLVQDPLSMEKPKSLNICEDAEQNVSVPGLSYFTPTNLEEVMEIIIRGNSNRTMSPTEANAVSSRSHAVLQIYITQTPKSGEKQEESESQNSHKVRSVFSFIDLAGSERASATKNRGKRLVEGANINRSLLALGNCINSLCEPRRRQHVPYRDSKLTRLLKFSLGGNCRTCMIVCISPSSEHYDETHNTLKYGNRAKNIKTKVSRNVVSVDRHVSEYVRTIYELRQKVSILQKRIAEESKQLALNKEVRKISSREIKMLDARSMLKNSFDGSRDLQKSLIEHVRTLRRIEDEITLTKMWISIAKESDAMSGHNIKSVETRLAKLYDQRSLITAKVNPEEICKTFQNSISHIVSSFKGEGADMYADMLQDDVDLLKSIIENQILDAKHESETFSSTSRKLIQNLFLLFPLLPGNAIDVNESLARAFDQLVGIVPSEPTIQVPNLIEKGKAPLLSMFEIPRSPSRFKARSPSKAARVLKKPLKKRVRFSEVPTTSSVPPVEIKNKDSKPKVEKSLDKHNMNNDRSFLVPSRDARNSLTSLSLHSNVAKNKSSHSSKWPTHTLSPIITTALKQPVRRISLVSQPLQKTGGTENTPNA
Protein: Echinoderm microtubule-associated protein-like CG42247 (Q9VUI3)
Organism: Drosophila melanogaster (Fruit fly)
Function: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000305}.
Interaction partners:
- Protein Obscurin
- Tubulin beta chain
- Tubulin beta-3 chain
- Tubulin beta-2 chain
- Tubulin beta chain
- beta-Tubulin at 65B
- Tubulin alpha-1 chain
- Reduced mechanoreceptor potential A, isoform B
- Doublecortin-like and CAM kinase-like protein
- RE09305p
Sequence:
MPQISPNAPLEGNVSPPPTQPHLDDNLHNGNGNGNGIHSSSSNINKHGSNINGNNDSNRSSPAKSPKRPVSSSFRIQNTSRYDNDEEDLAASEQVAGGDRQVPDYWQQRNGATTGATSGRQSRAISPGYLDNMSENSEQPPVVPLVRSKSRPEISSAAASRYNNLSYWKARRVVFYRNGDPFFPGVELRYRPGRDVTSLDNLLDKISPKMDLPRGARYVFSMDGDRKYHLDELEDGAFYVVSSFKAFKPASYGKKNGMWYASPGNQGWGSKPASRKPSIMEADLGTLSTTSGSIKRSAGRVIRIINNLDHSVQCRVLLNLRTSQPFEEVLEDLGQVLKINGAKKMYTGTGQEVRSFSQLRNEFADVDTFYLATGTALIAGSPIRRSRSRPSVVAAAPILPTDELPKVPLRGARPRSKSRPRILYAPESEILRPNGEYTMLDIMKEEPTKVTIRGLRRTFYPPVHHAPADNSPPDKKLQLQWVHGYRGIDARRNLWVLPSGELLYYVAAVAVLFDRDEDAQRHYTGHTEDIMCMDVHPSRELVASGQKAGRDRKSQAHVRIWSTESLQTLYVFGMGELDSGVTAVAFSQLNGGSYILAVDSGRESILSVWQWQWGHLLGKVATLQEGLSGAAFHPLDDNLIITHGRGHLAFWHRRKDGFFERTDIVKQPSRSHVTSVQFEPDGDVITADSDGFITIYSVDSDGAYFVRTEFEAHNKGIGCLIMLGEGTLLSGGEKDRKIAAWDSLQNYKKIADTKLPEAAGGVRTIYPQRPGRNDGNIYVGTTRNNILEGSLQRRFTQVVFGHGRQLWGLAAHPDDELYATAGHDKHVALWRKNKLIWTIQTGYECVALAFHPFGTLAAGSTEGHLLVINCENGAVMLTLRVCGSPLNCVAYNQVGDMIAMGSQNGSIYLFRVSRDGFSYKKVNKIRGSQPLTHLDWSMDGNFVQTVTIDFDLLFWDAKSLSPERSPIAMKDVKWLTNNCTVGFLVAGQWSNRYYSTTNTIVATCSRSAAHDMLASGDAEGYLRLFRYPCISPRAEFHESKVYSGMLACVRFLCGDHTLITVGGTDASLMVWDIVEE
Protein: Phosphatidylinositol transfer protein beta isoform (Q802Z3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004586}. Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004394}.
Interaction partners:
- Membrane-associated phosphatidylinositol transfer protein 3
- PITP-less RdgB-like protein.
- Arrestin-C
Sequence:
MVLIKQYQVLLPCSVEEYQVGQLYSVAEASKNNTGGGEGIEVLRNEPYEKEGEKGQYTHKIYHIHSKVPGFIQMFAPEGALVFHEKAWNAYPYCRTIVTNEYMKDDFFIKIETWHKPDIGTTENPHGLPPEEWEDIEIVPIDIADRSQVDDVDYKAEEDPAIYHSEKTGRGPLGPEWKKELHNGNCPYMTAYKLVTVHFRWWGLQGRVENFIHKQEKRLFTNFHRQLFCWLDRWVDLTMDDIRRMEEETQRELDQMRSQGSVRGMKAGED
Protein: Antizyme inhibitor 1 (AZI) (Ornithine decarboxylase antizyme inhibitor) (Q63764)
Organism: Rattus norvegicus (Rat)
Function: Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Ornithine decarboxylase antizyme 1
- Ornithine decarboxylase antizyme 2
- Ornithine decarboxylase antizyme 3
- Spermine synthase
- Guanidino acid hydrolase, mitochondrial
- S-adenosylmethionine decarboxylase proenzyme
- Spermidine synthase
- RCG27151, isoform CRA_a.
Sequence:
MKGFIDDANYSVGLLDEGTNLGNVIDNYVYEHTLTGKNAFFVGDLGKIVKKHSQWQNVVAQIKPFYMVKCNSTPAVLEILAALGTGFACSTKNEMALVQELGVSPENIIYTSPCKQASQIKYAAKVGVNIMTCDNEVELKKIARNHPNAKVLLHIATEDNIGGEDGNMKFGTTLKNCRHLLECAKELDVQIIGVKFHISSACKEYQVYVHALSDARCVFDMAGEFGFTMNMLDIGGGFTGTEIQLEEVNHVISPLLDIYFPEGSGIQIISEPGSYYVSSAFTLAVNIIAKKVVENDKLSSGVEKNGSDEPAFVYYMNDGVYGSFASKLSEDLNTVPEVHKKYKEDEPLFTSSLWGPSCDELDQIVESCLLPELSVGDWLIFDNMGADSLHGPSAFSDTQRPAIYFMMSLSDWYEMQDAGITSDAMMKNFFFAPSCIQLSQEDNFSTEA
Protein: Sphingosine N-acyltransferase lag1 (EC 2.3.1.24) (Longevity assurance factor 1) (Longevity assurance protein 1) (P78970)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the ceramide synthase complex required for C26-CoA-dependent ceramide synthesis. Facilitates ER-to-Golgi transport of GPI-anchored proteins (By similarity). Involved in the aging process (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- PIGF/3-ketodihydrosphingosine reductase fusion protein
- Sphingosine N-acyltransferase lac1
- Sphingolipid delta
- Sphingoid long chain base kinase 4
- Dihydrosphingosine 1-phosphate phosphatase C823.11
- Sphingolipid C4-hydroxylase sur2
- Transcription factor cbf11
- Uncharacterized protein C119.09c
- Transcription factor cbf12
Sequence:
MSNRKADEKHHMSSSSLTNDRSYIRNLSNRKTSISRKVPITRTLEDPSNFVAKDGTKLVQAPLFLLVWQKEICLSIIAICFACLLSPSLRPYAEPFIFLSYKQPDGSYGKGPKDACFPIFWVIVFTAFRVIVMDYVFRPFVLNWGVRNRKVIIRFCEQGYSFFYYLCFWFLGLYIYRSSNYWSNEEKLFEDYPQYYMSPLFKAYYLIQLGFWLQQILVLHLEQRRADHWQMFAHHIVTCALIILSYGFNFLRVGNAILYIFDLSDYILSGGKMLKYLGFGKICDYLFGIFVASWVYSRHYLFSKILRVVVTNAPEIIGGFHLDVPNGYIFNKPIYIAFIILLFTLQLLIYIWFGMIVKVAYRVFSGEEATDSRSDDEGEDEEASSTNEDK
Protein: BPS1-like protein (F4JI15)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- DNA replication licensing factor MCM3
- DNA replication licensing factor MCM5
- DNA replication licensing factor MCM4
- DNA replication licensing factor MCM7
- Cell division cycle 45
- Origin of replication complex subunit 2
- DNA polymerase epsilon subunit B
- Minichromosome maintenance 10
- Origin of replication complex subunit 5
- DNA replication licensing factor MCM6
Sequence:
MSQQRTRSRNPFKILFTKKNNARLSPKLLSLLNNFETNLTVSIRELVPKDKNDIVSVSWMIQAMQSLCETHKSIRTLVKDLEVPVSDLEENFIYIFSDFSLKRELCNAFTSEIYHLEHGNLLLKFAFSKLETNSGNILQRWNQHMVSKNPSIENWGAVLSRLVESMDHHHHISKKGKKKYSAEGKVLLRVLYGVKVKTLYIFSVFDASFSGSSKNLFYLTIPKEMEELPWVQAFMELQNTINPEIKNTFLSDGFTVIKDLEAVETGVKKLYTAVQEGSVPILLVEPLEKSVIELSERFELVSKETRCLSKMVISARDALLESLWTKCAEELGVTLPTMVKSVNIEEKS
Protein: Ubiquitin domain-containing protein 7SL RNA2 (At7SL-2) (Protein ETERNALLY VEGETATIVE PHASE 1) (Q9ZQZ6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Controls phase transition from the vegetative to the reproductive state. Involved in the maintenance of the shoot apical meristem (SAM) thus preventing inflorescence meristem (IM) formation and subsequent inflorescence stem development during flowering. Regulates leaf and organ morphology.
Subcellular location: Nucleus {ECO:0000269|PubMed:21624980}.
Interaction partners:
- E3 ubiquitin-protein ligase UPL4
- Protein NBR1 homolog
- E3 ubiquitin-protein ligase PRT1
- Ubiquitin-ribosomal protein eL40y fusion protein
- E3 ubiquitin-protein ligase UPL3
- At5g63780
- Ubiquitin receptor RAD23b
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Large ribosomal subunit protein uL18y
- Large ribosomal subunit protein eL42z/eL42y
Sequence:
MNVDIDTETGSSFSITIDFGETVLQIKEKIEKSQGIPVSKQILYLDGKALEDDLHKIDYMILFESLLLRISPDADPNQSNEQTEQSKQIDDKKQEFCGIQDSSESKKLTRVMARRVHNVYSSLPAYSLDELLGPKYSATVTVGGRTNQVVQTTEQASTSGTAKEVLRDSDSPVEKKIKTNPMKFTVHVKPYQEDTKMIQVEVNADDNVEELRKELVKMQERGELNLPHEAFHLVSSELPLIETKSFKWNRVADGDTIELIREK
Protein: TOMM20-like protein 1 (Q6UXN7)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion outer membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Mitochondrial import receptor subunit TOM22 homolog
- Mitochondrial import receptor subunit TOM40 homolog
- Mitochondrial import receptor subunit TOM40B
- Mitochondrial import receptor subunit TOM7 homolog
- Mitochondrial import receptor subunit TOM70
- Mitofusin-1
Sequence:
MPSVRSLLRLLAAAAACGAFAFLGYCIYLNRKRRGDPAFKRRLRDKRRAEPQKAEEQGTQLWDPTKNKKLQELFLQEVRMGELWLSRGEHRMGIQHLGNALLVCEQPRELLKVFKHTLPPKVFEMLLHKIPLICQQFEADMNEQDCLEDDPD
Protein: Amino acid transporter transmembrane domain-containing protein (Q581M5)
Organism: Trypanosoma brucei
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MLFLFHPFVPETLWVKEVPKSANRLQDAMSNSKQQQEVQTPNNLSNEPVQTEDNVKKGRNTFFTKVSLCVATVLPPGGIAASAFNMASTTIGAGIFGMPPAANSTGLIMGMFYLIFISSVTVFTMHNLSVAADRSGAPTFERATRALLGRGAAYVLAGIRALLGFSGCVAYVISVGDILSAILKGTNAPDFLKEKSGNRLLMAVVWACFMLPLTIPRHIDSLRYVSTFAVTFMVYFVIVIVVHSCMNGLSENIKNVSVTKSEDAEIILFNSGFQAIEGMGVFMFAFISQITAYEVYIDMKDRSVRKFVIAAIIANTLCCIMYIITAFFGYMDFGKTATSSILLMYDPVKEPAVMVGMIGVVIKLCVSYALVAMACRNALYDVVGKTADSLPFWKHCVSVITLSFLVLLLSIFIPKITTVFGIAGSVCGGSLGFVFPALLIMYSGGFTWQKVGPLYYITTYVVLLCGVFLIVFGTGSTILDTVRG
Protein: Probable zinc transporter protein DDB_G0283629 (Q54QU8)
Organism: Dictyostelium discoideum (Social amoeba)
Function: May be involved in zinc transport from the cytoplasm to either intracellular organelles or extracellular spaces.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MENFKNNELESSPIINKNNSSHSINNEDNNYYSHNLEHNDNNNNDNNNTITNSHINNHDHKHNHEHEHKHKHNHDHNHDHDHNHEEEYGHGNELEHNNDQEHNVGNKNLLTNNNNQSKKKKHGHSHGGGEDGSSSGGGGGRHGHGHSHGGGSGSDHNHGSSDEDDEESKPLNQLRNLDSKKKARYSLILALTLTTIFMVGEIVGGYFANSLAIMTDAAHLLTDIGAMFLSLFAMWISQHPPTSSMSFGFHRAEILGALVSVLMIWALTGVLVYEAIQRILYPPDAVDGKIMFIIASCGLFINIIDAIILHWGSGGHGHSHGGGHGHSHGIGGGTQKKKSKKNRLLNNQGQDIEDLGGENGKNKKGVRNINVHSAYIHVLGDCFQSIGVMVASCIIWVHPHWKIADPITTLIFSVIVLGTTIKLLRESLGVLMEGVPPEIDVSEVKGDLSEIEGVTEVHDLHIWSITLGRPALSVHLTILPTIDPEEILSIANKILLEDYEINHTTIQIEKPLVKDKCKDHSCPPPKPKKKKIKNDNLSSPPNQ
Protein: Laminin subunit alpha 3 (K7EIP4)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000256|ARBA:ARBA00004302}.
Interaction partners:
Sequence:
XFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTLEDGYIELSTSDSGGPIFKSPQTYMDGLLHYVSVISDNSGLRQEGCLRPRVRDQSWKHSETMSLRKLK
Protein: Leucine-rich repeat-containing protein (Q4GZE0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MHSLRSNKQEARVDNDPLQEVDYSYNVQQLQAEFHVLPPSEAYRELCFRHQCKPINSVANLFSSCVGEWNVTTHLDFSQSYIGPKGVRPVVELCKRLPALKSFNCANNYLTNNAVYFISRMAAFHPSLERLELSFNEFISWTGGNFLYELTLCNSNIKEVGVLHTKIPPNVAEEIFRQSRCNCVLVYQAMGRPPKQSSHPEAIHLRAMKRFFNDMQENGTVPASALVEGHRERCRILGEAYDASKYTKAFYDELSSRLPQDNISWEAFIITLKLDGSVYNEEAVKKLRRLFLEFNMEPTAELDGFVEVRDLPAMCTRLNNEHAPSTVIKNMCDVLGLDDTMTLQWDEFLSLMYNSVATNMEHGVNLRMASPHSAVKMLHL
Protein: Inactive ribonuclease-like protein 10 (Protein Train A) (Q9D5A9)
Organism: Mus musculus (Mouse)
Function: Secreted proximal epididymal protein required for post-testicular sperm maturation and male fertility. May be involved in sperm adhesion to the egg zona pellucida. Does not have ribonuclease activity.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Epididymal-specific lipocalin-9
Sequence:
MKVTLVHLLFMMLLLLLGLGLGLGLGLHMAAAVLEDQPLNEFWPSDSQNTEEGEGIWTTEGLALGYKEMAQPVWPEEAVLSEDEVGGSRMLRAEPRFQSKQDYLKFDLSVRDCNTMMAHKIKEPNQSCINQYTFIHEDPNTVKAVCNGSLVDCDLQGGKCYKSPRPFDLTLCKLAKPGQVTPNCHYLTYITEKSIFMTCNDKRQLETK
Protein: Basic helix-loop-helix ARNT like 1 (A0A669KBF4)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MADQRMDISSTISDFMSPGPTDLLSSSLGTSGVDCNRKRKGSSTDYQESMDTDKDDPHGRLEYTEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFPSTCSKKKDRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHSHVVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVLANVLEGGDPTFPQLTASPHSMDSMLPSGEDSFVVGGPKRTHPTVPGIPGGTRAGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSSGLLSGQAQENPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPSNDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL
Protein: Large ribosomal subunit protein P1A (60S acidic ribosomal protein P1-alpha 1) (A1) (P17476)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Plays an important role in the elongation step of protein synthesis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS10
- Large ribosomal subunit protein eL31
- Large ribosomal subunit protein uL24
- Large ribosomal subunit protein eL14
- Small ribosomal subunit protein eS21
- Large ribosomal subunit protein uL10
- Small ribosomal subunit protein uS5
- Large ribosomal subunit protein eL18A
- Large ribosomal subunit protein uL29
Sequence:
MSASELATSYSALILADEGIEITSDKLLSLTKAANVDVEPIWATIFAKALEGKDLKELLLNIGSGAGAAPVAGGAAAPAAADGEAPAEEKEEAKEEEESDEDMGFGLFD
Protein: Large ribosomal subunit protein uL30m (39S ribosomal protein L30, mitochondrial) (Q8SYI9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MNLGRLLNPLRSTACSVRSYGKHNKKFLYKNGQKFEGITYYPRTPDHQDPPVEPAKLFRVQRIRPLKGNPYWENRILKDLGLDGKQSDFTVVKNIPENNARLWKIKHLIKVTPVTFPYGEPTAQDVRHTILKENGECLVTKDLGPIDTRLAARQDYDEQPKRLDTDLLRKDARLKWLNPW