wanglab/gogpt-training-data huggingface dataset:
Protein: GRAS family protein RAM1 (Protein REDUCED AND DEGENERATE ARBUSCULES) (Protein REQUIRED FOR ARBUSCULAR MYCORRHIZATION 1) (LjRAM1) (A0A145P7T2)
Organism: Lotus japonicus (Lotus corniculatus var. japonicus)
Function: Transcription factor acting as a central regulator of arbuscular mycorrhiza (AM)-related genes (e.g. PT4) required for the morphogenesis of arbuscules upon symbiosis with AM fungi (e.g. Rhizophagus irregularis). Also involved in restricting mycorrhizal colonization of the root meristem (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:25560877}. Cytoplasm {ECO:0000269|PubMed:25560877}.
Interaction partners:
Sequence:
MINSMCGSSVSLKSENSRNKPQPTSPNESVLQSKKNATQSSADLEQTSLNLTPPSLNLPALKFDLDGDVEVQSPDSSMWESFFSDHLLDGDFMISSPVRNNVPSPQASTFNSNYNYAHQGIQSQSLSGCSPPRFSSPLGAFNSNKGKGLSPLHRVFNSPNNQYMQHVENLALPAIEEFLEEYQGDHGLGGGGGYSNSSNKVSSDIGSSSECFDMQNHIPSMLDSLTMQNSSRYCGSVSEDSSVHGGSSQLSQDSDFYHQMGSMASASLSQALQQERYQEKQQKQHQTQQQQQPQQQQQNLTVPIPIGMDQEQDSGLQLVHLLLACAEAVAKEEYMLARRYLHHLNRVVTPLGDSMQRVAACFTESLSARLAATLTTKPQSISNGTSMPRSSSSSCLSPFPSNSIEVLKIYQIVYQACPYVKFAHFTANQAIFEAFEAEERVHVIDLDILQGYQWPTFMQALAARPGGAPFLRITGVGPCIDSVRETGRCLTELAHSLRIPFEFHPVGEQLEDLKPHMFNRRVGEALAVNTVNRLHRVPGSHLGNLLSMIRDQAPNIVTLVEQEASHNGPYFLGRFLEALHYYSAIFDSLDATFPPESAQRAKVEQYIFAPEIRNIVACEGAERIERHERLEKWRKIMEGKGFRGVALSPNAVTQSRILLGLYSCDGYRLTEDKGCLLLGWQDRAIIAASAWRC
Protein: VWFA domain-containing protein (Q57ZW5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Telomerase-associated protein, putative
Sequence:
MSGSSLACNRDVSLTIGDVTVPVPANVSHPERVTWVLPGDTTNSGAFHIGEDAADELSLDVGDMFFHLGDNATRQYLRWICQKELLKQDMCLTGEPGPALRWLVLLYSRLTRREVQCVSLNRDTNEGDLGQRREIRNGTLSYEDQSVVIAAREGQLLLLEGLERVERNVLPVINNLLENREMHLENGMVLIHPERYDKIFNEALCEELKGGRQDANVEGGIGNQIPQAVHAKLQRMGFIRVSESFRVIGITAPVPPYDGTPLDPPLRSRFQCLYVDLPPPTLAATNVTNMAPGGRARGVFESLLKLRASIEEMNARTRGFTSGGTQGRDSAVGGCVSSLCGLQTIGSYEVAQVFRQFMLFPDVPVSELLLRSFPWTLYAQQTGSGSGTYEESMRRLRDYERVLAACDIGTPLSNHICHHSDVSVRDSGKPTDHCTHEDCAVRSSKHYNDVVFIDNVRVAKSKVLAVLQHPVVVGDACVDGMKGKYQLPLYLGEFALKSSRGGPSSPSSGRKWRTVDVKVYCSSSSTVFTPGHVHVLQSMLQLHIAGRHILLLGSSGSGKTTLLHEFARLLGYQTETMYLYADMTIKDLFQRRATDSVSGDTVWQNSALVDAALNGRMAVLDGIDKMPLGMLSSLQQLLIDGSTSLCDGSVLKSFKEYGIIKEKLRATEEEMKARRIFPIHPSFRVVGTARFPALNSNGTGNKVWQNQWRVTHDVTELFGVVQMPSCSQSLFRAILLRVAELELQFCGNEKVDGIRASVGPEGGISSGLKRDVDTLLRLRDELERLQVTEPKTPQLSLRQLLNLTRFRVRYPDDFNISVESTLLLPLLSSLVAEKVRQVMQICGFTCTSGLAERKQDPLRSSSVSKSSMGETLNCHSLKEFLLPCDPTIPNAGAGKAEGIEVSRVFGLGDKPILRINRNYGAKEKAMVPHVPHFHPNPVHESVIVWLAKQYAVGNNILLIGNQGVGKNKVVDAFLARVGTPREYIQLHRDTTVGSLTINPTVENGRVVWADSPLVRAVQQGHCLVVDEIDKAPVEVVQVLKGLIEDHEMRLRDGRQILGPRAHVVRFSISSSDYGSSEQKNIINMHPDFRVIVLANPPGFPFHGNDFYRECGDLFAPSVMLNADAHSQLQVLRAYGVNIPDALLMSLIECFQRLQTDFEEGNITYPFSLRELIAVVRHMSMFPGDGVYAALNNIFNFDVFDENTLRLVRNVLRLHLDPLVQFGGMQKLLPLRTSRAVPLRPSPSLIHMSAKSPAFLPLKLGEVVMSLPVRRLTDLECGGAINWKSAPVWCESYNATDFAADVSANGGLVGFSEWTTATRLPFLQQGDRVIRVAVEAPECVVGESKSVAVLFTRQHVLREEMNGSSSPLATTEIFLAIASLPSVASIAATAVGRKRLAAGQVQLLNLTDLLPLNSLPSSSLRFLGTEASGILASQALKESSHGAFGTSPSFVEVACASSGSILLADASALGLCSTSTALPRGQVRGQGDAAGDKLLGSVLVVHLMPPSSDVALTRHTVCPGCNLVAMTRPREPELYVWSNGHRVGVTLPAEDIRGIHFFANNYASVHLSKSESTFCGVMKLSLMSDGVATASLCLLPNEINGVVVGLTGTKEPTPTEAAMGPVTPEELQGAIIVAGAGSDSEKEGVLYTMVESYSSRSQSWSMRTFANPSISPAVCSDLNHHGTIGIDRVHKQLVVASGSDGVDTCGSLFAVDYHHHTVRHFAPTPTTSSRSSSVKPSYPCFSLDEVAGNILRYDEVNRQLLIGDLVAERVECRHRQLSALLQGSVKQVGAAAATPQGKLSMSYCTSRYAASNNLKHGREDNEEHHGGNTYAGGTGGTDTAGLGGLVGPYRLDKGWPVHQVSPEAKQQVPQHIIEEARRMGRVALQERLREIGMTSTEYERYGALQGRVRAPVAILRSMLSGLKAAEGERVWLRGQTDGVWDDSKIVEGIVGERNIYKRRADYADASPFQLKRKKRLLFVLDVSASMYRFEGMDQRLTKLLESTVMVMEAFTGYEEKIDYAMVGHNGDSACIELVPFGKPPTNQKERAEVCQRMVAHAQYCWSGDNTVQAMRQSIELVTAEKGEAYLVFVISDANLSRYGIEPGELGEIMESNQEVQMFCIFIATLGEQALNLREKLPSGHGFECMDTQALPHILKQIFLSVNLL
Protein: Eukaryotic translation initiation factor 3 subunit B (eIF3b) (eIF-3-eta) (eIF3 p110) (Q8GUM1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|HAMAP-Rule:MF_03001, ECO:0000256|PIRNR:PIRNR036424}.
Interaction partners:
- Eukaryotic translation initiation factor 3 subunit J
- Eukaryotic translation initiation factor 3 subunit D
- Eukaryotic translation initiation factor 3 subunit G
- Eukaryotic translation initiation factor 3 subunit G
- Eukaryotic translation initiation factor 3 subunit K
- Eukaryotic translation initiation factor 3 subunit J
- Eukaryotic translation initiation factor 3 subunit L
- Eukaryotic translation initiation factor 3 subunit E
- Eukaryotic translation initiation factor 3 subunit A
- Eukaryotic translation initiation factor 3 subunit C
Sequence:
MAAVVDIDVLTAQLGINWSDVNLDSIQLPPGNDFGIESDDESVYQDDQSEFDTGFGNIIVVDHLPVVPKEKFEKLEGVVKKIYNQLGVIKENGLLMPVDPDTKMTLGYCFIEFNTPQEAQNAKEKSHGYKLDKSHIFAVNMFDDFDRLMNVKEEWEPPQERPYVPGENLQKWLTDDKARDQLVIRFGHDTEVYWNDARQKKPEPVHKRSYWTESYVQWSPIGTYLVTLHKQGAAVWGGADTFTRLMRYQHSMVKLVDFSPGEKYLVTYHSQEPSNPRDASKVEIKVFDVRTGRMMRDFKGSADEFSIGGPGGVAGASWPVFRWAGGKDDKYFAKLSKNTISVYETETFSLIDKKSMKVDNVVDICWSPTDSILSLFVPEQGGGNQPAKVALVQIPSKVELRQKNLFSVSDCKMYWQSSGEYLAVKVDRYTKTKKSTYSGFELFRIKERDIPIEVLELDNKNDKIIAFAWEPKGHRFAVIHGDQPRPDVSFYSMKTAQNTGRVSKLATLKAKQANALFWSPTGKYIILAGLKGFNGQLEFFNVDELETMATAEHFMATDIEWDPTGRYVATSVTTVHEMENGFTIWSFNGNMVYRILKDHFFQLAWRPRPASFLTAEKEEEIAKNLRNYSKRYEAEDQDVSLLLSEQDREKRRALNEEWQKWVMQWKSLHEEEKLVRQNLRDGEVSDVEEDEYEAKEVEFEDLIDVTEEIVQELM
Protein: Protein HYM1 (P32464)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Interaction partners:
- Serine/threonine-protein kinase KIC1
- Leucine-rich repeat-containing protein SOG2
- Serine/threonine-protein kinase CBK1
- Cell morphogenesis protein PAG1
- CBK1 kinase activator protein MOB2
- Metallothionein expression activator
- Sporulation-specific protein 1
- Translocation protein SEC72
Sequence:
MFKKYKNQDLDMAFWWKKNPKTPSDYARLIIEQLNKFSSPSLTQDNKRKVQEECTKYLIGTKHFIVGDTDPHPTPEAIDELYTAMHRADVFYELLLHFVDLEFEARRECMLIFSICLGYSKDNKFVTVDYLVSQPKTISLMLRTAEVALQQKGCQDIFLTVGNMIIECIKYEQLCRIILKDPQLWKFFEFAKLGNFEISTESLQILSAAFTAHPKLVSKEFFSNEINIIRFIKCINKLMAHGSYVTKRQSTKLLASLIVIRSNNALMNIYINSPENLKLIMTLMTDKSKNLQLEAFNVFKVMVANPRKSKPVFDILVKNRDKLLTYFKTFGLDSQDSTFLDEREFIVQEIDSLPRIISSTTEVSNNNASSSNVASITSPSSVMNNQSSILTHSTSPDSR
Protein: Pulmonary surfactant-associated protein A1 (PSP-A) (PSPA) (SP-A) (SP-A1) (35 kDa pulmonary surfactant-associated protein) (Alveolar proteinosis protein) (Collectin-4) (Q8IWL2)
Organism: Homo sapiens (Human)
Function: In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages (By similarity).
Subcellular location: Secreted {ECO:0000269|PubMed:26792177, ECO:0000269|PubMed:32855221}. Secreted, extracellular space, extracellular matrix {ECO:0000305}. Secreted, extracellular space, surface film {ECO:0000305}.
Interaction partners:
- Surfactant protein C
- Pulmonary surfactant-associated protein B
- Surfactant protein A2
- Secretoglobin family 3A member 2
- Pulmonary surfactant-associated protein D
- Uteroglobin
- Homeobox protein Nkx-2.1
- Lactotransferrin
- Deleted in malignant brain tumors 1 protein
- Advanced glycosylation end product-specific receptor
Sequence:
MWLCPLALNLILMAASGAVCEVKDVCVGSPGIPGTPGSHGLPGRDGRDGLKGDPGPPGPMGPPGEMPCPPGNDGLPGAPGIPGECGEKGEPGERGPPGLPAHLDEELQATLHDFRHQILQTRGALSLQGSIMTVGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGPSPGDFRYSDGTPVNYTNWYRGEPAGRGKEQCVEMYTDGQWNDRNCLYSRLTICEF
Protein: Defensin beta 136 (Beta-defensin 136) (DEFB137) (Q30KP8)
Organism: Homo sapiens (Human)
Function: Host defense peptide that exhibits antibacterial and antifungal activity. Exhibits antimicrobial activity against E.coli, S.aureus and C.albicans (in vitro). Has high lipopolysaccharide (LPS)-binding affinity, and may thereby be involved in immunoregulation through LPS neutralization.
Subcellular location: Secreted {ECO:0000250|UniProtKB:P60022}.
Interaction partners:
Sequence:
MNLCLSALLFFLVILLPSGKGMFGNDGVKVRTCTSQKAVCFFGCPPGYRWIAFCHNILSCCKNMTRFQPPQAKDPWVH
Protein: Protein Mis18-alpha (Q9CZJ6)
Organism: Mus musculus (Mouse)
Function: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q9NYP9}. Chromosome {ECO:0000250|UniProtKB:Q9NYP9}. Chromosome, centromere {ECO:0000250|UniProtKB:Q9NYP9}. Note=Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin. {ECO:0000250|UniProtKB:Q9NYP9}.
Interaction partners:
- Mis18-binding protein 1
- Protein Mis18-beta
- Centromere protein K
- Histone H3-like centromeric protein A
- Centromere protein W
- Centromere protein Q
- Holliday junction recognition protein
- Centromere protein I
- Centromere protein R
- Borealin
Sequence:
MSSESPLLEKRLSEDSSRYLRLQKWANMSSADALGLEKERPEEKAAAAENPLVFLCARCRRPLGDSLTWVASQEDTNCILLRSVSCNVSVDKEPKLSKCRDEDGCILEALYCTGCSLSLGYVYRCTPKNLDYKRDLFCLSVEAVESYTLGSSEKQIVSEDKELFNLESRVEIEKSIKQMEEVLTALQKKLREVESKLSLASRGS
Protein: CD226 antigen precursor (Zgc:158817) (A1L2D6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
Sequence:
MVAVQKDYWYFLVLVMLLCFLKGSVQMKAPESSVVLQEGMVLDCLCPWTGQLIMVSWTKTPFAKPIAVYHPQYGTNFGSSYEGRVEFLKSTAMDGSISIMNVTEGDIGQYHCSLQTYPQGSWTKDTFVQKAAITTSTSISIQADTKLVVAENDNLTIMCDLVHDGKIYQVSIEKLDTEEGNSNIIATCEMLEDGVELRNFSNRGLLNCSEDMEVSLHLTNIIKEDGGLYRCNFSTNNGIQSTTVLLTTVPAQDFPGLHHMLYVYIGGGVIGVVALMTLLLTWLNRMKRKKEEYRIKLHPAKRQRNPYDQSCVYDRMKKGTRTRAKDKEIYMNFQIVRAHAKHKR
Protein: CS domain-containing protein (Q383D2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSSDATAAAVNWSQGDEGDTALEICVPIVLPQSGRAKELTVEVKDLAVLRVSHRDTIILQWRLYEPVAEEVEWRVENEGSLLIMDMVKRSCAVWPCLLDLPMRADDKLLRSTAELDNLFREHHPPLPPDPSLERKGAGAAAVDKVDGNGGEAGTAAVGGEDDLERLLEEAAEEVVGEGAATEENNDREFINAELENCRTEIEEIQKKLDEVMKTLEDGADGEAKQQALKQKTILEEMLRLHFEICEKRRLPSSLSGFIEITQLDIRKSRVNVGELSEEEREEYASDEERAMTAHELMTRGLQHFEQQEIQPALHFLRLAALHHNHDQSTIILHSIYSQLNSPRGAFILLRRALQDDNISSTANLKVAEQFDVGARHFLPMFPAALYFYQRAAKAGCVSAMLAIAQLYLRGCTSSTMLSAKQIERLRNTDMYQEWLQRAIDRGCGSANFVKGCAHLKGEHGCVKSYKLAKEYLDRATAAQPKIAQRAPQVYVMLEKLRQEEEGVASLSASTSLSLSKGNYANGRAGTNGDGDAVCVTSSVERLNNMTSKPYASASAGPGRLKKGNQRSGAKAFWEGAVTTGLTLYSLYTLAFPVRLLILPHIYTLLSHVVDRVPWLAASQPLQF
Protein: NADP-dependent mannitol dehydrogenase (MtDH) (EC 1.1.1.138) (Mannitol 2-dehydrogenase [NADP(+)]) (allergen Alt a 8) (P0C0Y4)
Organism: Alternaria alternata (Alternaria rot fungus) (Torula alternata)
Subcellular location: Vacuole {ECO:0000269|PubMed:22078468}.
Interaction partners:
Sequence:
MPISVPQATELKDLFSLKGKVVIVTGASGPTGIGTEAARGCAEYGADLAITYNSRAEGAEKNAKEMSEKYGVKVKAYKCQVNEYAQCEKLVQDVIKDFGKVDVFIANAGKTADNGILDATVEQWNEVIQTDLTGTFNCARAVGLHFRERKTGSLVITSSMSGHIANFPQEQASYNVAKAGCIHLAKSLANEWRDFARVNSISPGYIDTGLSDFVPQDIQKLWHSMIPMGRDAKATELKGAYVYFASDASSYCTGSDLLIDGGYCVR
Protein: C-type lectin domain family 18 member C (Mannose receptor-like protein 3) (Q8NCF0)
Organism: Homo sapiens (Human)
Function: Binds polysaccharidesin a Ca(2+)-independent manner with a preferentially binding to fucoidan, beta-glucans and galactans.
Subcellular location: Secreted {ECO:0000250|UniProtKB:A5D8T8}. Endoplasmic reticulum {ECO:0000305|PubMed:26170455}. Golgi apparatus {ECO:0000305|PubMed:26170455}. Endosome {ECO:0000305|PubMed:26170455}.
Interaction partners:
- Trifunctional purine biosynthetic protein adenosine-3
Sequence:
MLHPETSPGRGHLLAVLLALLGTAWAEVWPPQLQEQAPMAGALNRKESFLLLSLHNRLRSWVQPPAADMRRLDWSDSLAQLAQARAALCGIPTPSLASGLWRTLQVGWNMQLLPAGLASFVEVVSLWFAEGQRYSHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQAAIEAFVCAYSPRGNWEVNGKTIVPYKKGAWCSLCTASVSGCFKAWDHAGGLCEVPRNPCRMSCQNHGRLNISTCHCHCPPGYTGRYCQVRCSLQCVHGRFREEECSCVCDIGYGGAQCATKVHFPFHTCDLRIDGDCFMVSSEADTYYRARMKCQRKGGVLAQIKSQKVQDILAFYLGRLETTNEVIDSDFETRNFWIGLTYKTAKDSFRWATGEHQAFTSFAFGQPDNHGFGNCVELQASAAFNWNNQRCKTRNRYICQFAQEHISRWGPGS
Protein: Phosphatidylinositol transfer protein alpha isoform (PI-TP-alpha) (PtdIns transfer protein alpha) (PtdInsTP alpha) (P53810)
Organism: Mus musculus (Mouse)
Function: Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes. Shows a preference for PI and PC containing shorter saturated or monosaturated acyl chains at the sn-1 and sn-2 positions (By similarity). Preference order for PC is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 and for PI is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 > C20:3 (By similarity).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:7654206}. Nucleus {ECO:0000269|PubMed:7654206}.
Interaction partners:
- Membrane-associated phosphatidylinositol transfer protein 3
Sequence:
MVLLKEYRVILPVSVDEYQVGQLYSVAEASKNETGGGEGVEVLVNEPYEKDDGEKGQYTHKIYHLQSKVPTFVRMLAPEGALNIHEKAWNAYPYCRTVITNEYMKEDFLIKIETWHKPDLGTQENVHKLEPEAWKHVEAIYIDIADRSQVLSKDYKAEEDPAKFKSVKTGRGPLGPNWKQELVNQKDCPYMCAYKLVTVKFKWWGLQNKVENFIHKQEKRLFTNFHRQLFCWLDKWVDLTMDDIRRMEEETKRQLDEMRQKDPVKGMTADD
Protein: Uncharacterized transporter C22F8.04 (Q9UUI8)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane {ECO:0000269|PubMed:10759889}; Multi-pass membrane protein {ECO:0000269|PubMed:10759889}.
Interaction partners:
- Putative transporter C83.11
- Uncharacterized protein C12G12.12
- UDP-galactose transporter
- UDP-N-acetylglucosamine transporter yea4
- UDP-galactose transporter homolog 1
- Golgi apparatus membrane protein tvp15
- GDP-mannose transporter
- Pyruvyl transferase 1
Sequence:
MSSKLTVNAHYSPLKDEDPLDHIDSQTALDSMETDSTGKSSLYFSKSDDPLSKDIEDGISTRKLEEMSVLEANAKEPDSENAPVSRLTIFFAVSSQIVFAILVTILNKQALNIINAPLLMLSFQMAFTSLMVKMYWRFSSVHFQTLRLASAIQLKKFIFVKILGIVSKTYCLAFVPVSFYQISRGLLLPFTILLSFVLLKQKTRLFPFGGCLLVMLGFGFGVRFESHVAPIGIILGVWSSFTTAIESVAVKHYVHEYPTLDLIYIFSALMSVFCLLLSVASLELLHTVQEVVGMQAIKFFIVLILSSLSNFYLNIATFTQIKVTSPVTYMISVSARSILQTLLAVAFLGETLYGNRIYGVILILVGTLLYTLAKEHERRVASA
Protein: nucleoside-diphosphate kinase (EC 2.7.4.6) (E7ERL0)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVLLSTLGIVFQGEGPPISSCDTGTMANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCIQVGR
Protein: Uncharacterized protein (Q385C6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MESVPRNGKTTCGGDVSHLGARMGNYSQPKPAVTDKKGRPLNKDTSEDCGSSGPTTSCDANTAYALNLLRGGKGSSLRGVSTHSAGCQSESGASSVVSSTEHVQNNKVSSLPSKKRRRGIVGPVPATAASAHPGDFSPRTSSGSEEKSSNRGSVATSASNQEATCAANPSGIDSSRCNSKRAAVEYASLKGTFIAGKFEAGSCTNVSLIHSVDREVDEETRASLENTGGVEATENGGSHTLEMIVNSASSCTNGLVVPKGDHCPILTSDLPFHARRGGEGDVSLPPYLLLTERDLKVCCQSFTARDQSADDGDEDGDVLYAGSSESGGDSQLSYLDDTDEHSAIVNKLAPLSASTLRPAAKYWGVGGEEYGEDACRVGIASRICSLTVSICLATSDRMDQRGFASSSSEPPNSNQRRGKCNVSVNTASLESGREGSIAGGSGNNANGVTTSSGIREEERMEKLLYLRRQIKSLGGKKLEYFSHAFGYKDCDCQKDVVCMAASALAVFMYFSPLPLPLLEDICRELSISTDCAGKEPLDFNVRAECLAEKISSHFYPMCRGFPPVTKCPLMPQMQIHEHAPGRYTCTVDNAELLEELPLHRLISNQFSCKKIRWQAILMLCDNELTFHVWHRHSGPLRARMVIRSQDPKRKRRNNKNNNNNNNGSEGNGEDLSSQNALKERPVLFLEKEVEAAPGELVGYDNFVQLTVALRSQANAQRDYRLYNSAEDRLTFQFALNLLNLDGTPFADSGSKKTTSNTNSGKGVSGSHQVNSAELTGTSAAEGKRRKEVEKAVQKLEKLETQEREALNKMCVNAHRQLMDDYNRGCQKAVQKKKERERKALLAKVGPNPELQRELNSLTQTVAANRTQVAKLSKEKAKEEENVQRLQNQIEEDNRKLEELRRQFKSLCETLSRIEKDKKALVERKKEWEGFGQHRGADMPVALNIPGLTATRHDKLAIDDVQSFLVFAATKDSALDASAGTPPSTNLTPQLHPAEQGTTGTRAVSPVGVTGSSINGAGVSVPLPRSAGTVGGGSSFAPPATGCLAMDLSWELYSKRPPFTTMLANNNGGNALGSLAVTCDASSPPPSQRHQHPIDISQLTCEVSDDAPITDRSSPTSNGGFTVTAVFGAPDSTSRFSLDANAAPYTPTPPISAQPASGAVPHAGFTPNGVPSDPLLRLSPQTSSPSVPYSGSSSMTAGCAFPEKPRYTYVSTPIANLSTSPGIGLFGIKSFGPSSIGGEPSETQSRSEEGLRFPTAQWSF
Protein: Histone deacetylase 11 (HD11) (EC 3.5.1.98) (Q9GKU5)
Organism: Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- AT-rich interactive domain-containing protein 4A
- AT-rich interactive domain-containing protein 4B
- Core histone macro-H2A
- Histone H2A
- Histone H2A
- Histone H2A
- Histone H2B
- Nuclear receptor corepressor 1.
- Nuclear receptor corepressor 2.
- Histone H2A
Sequence:
MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGGTIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVERNIEKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRHVPILMVTSGGYQKRTARIIADSILNLFGLGLIGPESPSISAQNSDTPLLPPAVP
Protein: GRB2-related adapter protein 2 (Adapter protein GRID) (GRB-2-like protein) (GRB2L) (GRBLG) (GRBX) (Grf40 adapter protein) (Grf-40) (Growth factor receptor-binding protein) (Hematopoietic cell-associated adapter protein GrpL) (P38) (Protein GADS) (SH3-SH2-SH3 adapter Mona) (O75791)
Organism: Homo sapiens (Human)
Function: Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.
Subcellular location: Nucleus {ECO:0000269|PubMed:21179510}. Cytoplasm {ECO:0000269|PubMed:21179510}. Endosome {ECO:0000269|PubMed:21179510}.
Interaction partners:
- Lymphocyte cytosolic protein 2
- Linker for activation of T-cells family member 1
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
- Growth factor receptor-bound protein 2
- SHC-transforming protein 1
- Proto-oncogene vav
- T-cell-specific surface glycoprotein CD28
- FYN-binding protein 1
- Tyrosine-protein kinase ITK/TSK
- Tyrosine-protein kinase ZAP-70
Sequence:
MEAVAKFDFTASGEDELSFHTGDVLKILSNQEEWFKAELGSQEGYVPKNFIDIQFPKWFHEGLSRHQAENLLMGKEVGFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNYFLWTEKFPSLNKLVDYYRTNSISRQKQIFLRDRTREDQGHRGNSLDRRSQGGPHLSGAVGEEIRPSMNRKLSDHPPTLPLQQHQHQPQPPQYAPAPQQLQQPPQQRYLQHHHFHQERRGGSLDINDGHCGTGLGSEMNAALMHRRHTDPVQLQAAGRVRWARALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKLGLFPANYVAPMTR
Protein: Zinc finger protein 185 (LIM domain protein ZNF185) (P1-A) (O15231)
Organism: Homo sapiens (Human)
Function: May be involved in the regulation of cellular proliferation and/or differentiation.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:16799630}. Cell junction, focal adhesion {ECO:0000269|PubMed:16799630}.
Interaction partners:
- Trefoil factor 3
Sequence:
MSISALGGRTKGKPLPPGEEERNNVLKQMKVRTTLKGDKSWITKQDESEGRTIELPSGRSRATSFSSAGEVPKPRPPSTRAPTGYIIRGVFTKPIDSSSQPQQQFPKANGTPKSAASLVRTANAGPPRPSSSGYKMTTEDYKKLAPYNIRRSSTSGDTEEEEEEEVVPFSSDEQKRRSEAASGVLRRTAPREHSYVLSAAKKSTGPTQETQAPFIAKRVEVVEEDGPSEKSQDPPALARSTPGSNSADGGRTKASRAIWIECLPSMPSPAGSQELSSRGEEIVRLQILTPRAGLRLVAPDVEGMRSSPGNKDKEAPCSRELQRDLAGEEAFRAPNTDAARSSAQLSDGNVGSGATGSRPEGLAAVDIGSERGSSSATSVSAVPADRKSNSTAAQEDAKADPKGALADYEGKDVATRVGEAWQERPGAPRGGQGDPAVPAQQPADPSTPERQSSPSGSEQLVRRESCGSSVLTDFEGKDVATKVGEAWQDRPGAPRGGQGDPAVPTQQPADPSTPEQQNSPSGSEQFVRRESCTSRVRSPSSCMVTVTVTATSEQPHIYIPAPASELDSSSTTKGILFVKEYVNASEVSSGKPVSARYSNVSSIEDSFAMEKKPPCGSTPYSERTTGGICTYCNREIRDCPKITLEHLGICCHEYCFKCGICSKPMGDLLDQIFIHRDTIHCGKCYEKLF
Protein: Hybrid signal transduction histidine kinase M (EC 2.7.13.3) (Q54SK5)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Acts as a receptor histidine kinase for a signal transduction pathway. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain (By similarity).
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
Sequence:
MSNYLNANSTENNNNNNNNNNNNNNNINNNFNTTDFKIVGNFNTPPIGSNNNNNNNNNSISTQSLQTINECNSGGEQSPKIKTNNNSYNTPVSSSTSTTGTNTTPMKSTPIHNSLQNIFKNANRSNLNNNNNNNNNNNNNNNNNNNNNNNNNSGCGSGSLNSVNNNNNNNNNNNNNSNNNNSNSNSNSNNNNNSNSNNNNNNSNSNAYPLKYYQHPQQSCSNLDSFENLSPLRQSSTLLNFSSNNNNNNNNNNNNNNNNSNNNSSNNNNKNNSSKNKVGGGNNKNNGGDDSAQFISSDNKYNTVGNETHHHHHHQLHNHRHSNVQGSSSPIKSSPKLISSQSLGNIFSQISPNIALTTNISPHGSPFSSSSSSRKSSSSPSFLNQNNQNNPNNQNNQNNSTSPHEKSFLNNSNDSFDYNDNSKRLRNRLTRNTGYSSTGSIGNSSSSSFYNNNNENSNIYSKIKHTRSSSGGNKPSPKYFQTSQAIYTPPYPQPYPQPPQLPPPSSSSSLSKENDNVDNNNTNNNNNNNNNNNNNNNNNNNESFFSSKGTMNLIHISLLSVLAFYIFLMVSKKFLFRVFQWNNNINSLFILIFSFHFIFSSILMFLLVVLLKMKKYSHSISQSARESLRNSRVIPSLLNFFLSDYIFLGLVLSGLVNILQVNLFFNPKDPLLNLDSISNISTAIEFLVVGIVLNFSHIPKKMYNSRYSEFRVSSSISPYFQDESYNVNNIINNDNKNKINDKSDNSNSITNNNNINNNIDNNNNSSSNTKINNDLNFDNNIKNNDINNNITNNNNNNNNNNNNNNNTNNNNNNNNNNSNNNNNNNNNNSNKNNNTNSNNNNNNSSNNNNTNNNKINDNKNNNNNNNNNNNNNNNNNNNNNNEEDDEEEKNDWSYSFQIFFTRIFLCLSITYTLIVLRLNYDPLNQFLQQSSSFGSGANGNSGGGNVNTIISPVQFQAPLATLLHFIQLVLLLVNYNRFRTNRFFSLILSTIFIEVSSWETFGLNSRLFESYIFEALLIRRWIRACSVGFPIVGIILDIYSGWMSINQSIKSIDQQNIMIVNRFNYLCSNVKKQEELTQYNSQFYIESMNQFKRLVQNTGSIISLIYDTDVQPNQEAYLSKFSSSYEQLSKLTKECLFYSEIKQLKRNDVENLSFVVSNLLEDLISTPSIRTQFEEKEIDLFYLIDKDVPLSLVGDSQKIKQILLKLITNSIKATYEGEVYIRVSLSSNLGVLKQQPIHHHRHHHRHHHHHHHHHHHHIIDDDDYDDDNDDDNNTEDSSSCCNIDELSDKIKDNQDENLELKKSNNDKIIENKENQENNNNNNNNNNNNNNNNNNNNNNSNNNTNININTNNNNDSNNNNCINNDLKNNNNNSNNNVNNNNNNINDSNNNNNSNNNNINNNINNNINNNNNIKKKKKKNEFTVYFSVIDSGSGIDPYSTNLLFQPFSLSSYNVNSTNTDGEFGLGLAICKQLSNLMNGEIKYETEMEKGSVFELQVPMKCDSISSITSSMNSTTNTTNHYPRIMNNQSSKFFANSKWGEGLKILVIDDNPNIGKVIAMHLEPFGFKVFQRTTFQSAIYFFNERNGDFNLILLDPLIPSLVIDEIKQMKQDSSNIIKNPPLVIMCTAKLRKSLNVDNVHYLYKPIKREQLTVLSQLLPNTSTINPIYSNQNLNNSGSSNGGGGGGGGGGGGGGGGGSGSSNIDFNKTKLGGSNISTGIGNSGLINSNNIPTPVNTPSNIIPNLLSCQSLLTSLNNANIPQLTNDIGITNNNINNNSLMFTTPNSTLSNNGITGLDNNSNNDTGSIDNNSNISTNIDNNNDYFIRNNGIPPQNDMNTYNNYVLNHQQGVLPKSLSVPSTPLSYNMLPTNLNINAKRSSLQPLNENSVLPTNLTPPILSASPQSLLPMGNDINSILPNTQQSQIDLQSQIELQPLLQSTIIRNDRGGDILPDSTLEGQITNLSGNNSTISINPPLPETNNNTTTTTTTTQPKKSPILTSSNGSDKSEGSTGSNRSKSRISFLNSSNSGLLKNNLGEDIYCKGDQSEGIPIPKSERTSDSSSSSSSSDSHGQDDHSYRLEDFSISSPSSQSPLLDLSGTSGTSGTTNLANSGINSGSGSGGGDIINQNQLITSNQLFQQQLQQQQQPQQQQPPGTPTISPSSSFPLLPIPRDIINSSGASSGIKVKSSTSIPDYVQVSPRRFSGSSTGSGSSVASPQLLSTSNQLNNNINNLNLNSNNNNNNNNNNNNNNNTNNDNNNNNDNNYNVNILLVEDNLVNAKIAMTVLRKHNFRVELSKNGQLAMERIKQSHSSFDLILMDIHMPVMDGITCSKLTRKFETEHGLKHLPIIALTADATTGHKNLCLEAGCNEFMSKPLDYALLISLLKKLVFNKDQ
Protein: Glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) (Q7YYQ9)
Organism: Cryptosporidium parvum
Interaction partners:
Sequence:
MTATLGINGFGRIGRLVLRACMERNDITVVAINDPFMDVEYMAYLLKYDSVHGNFNGTVEVSGKDLCINGKVVKVFQAKDPAEIPWGASGAQIVCESTGVFTTEEKASLHLKGGAKKVIISAPPKDNVPMYVMGVNNTEYDPSKFNVISNASCTTNCLAPLAKIINDKFGIVEGLMTTVHSLTANQLTVDGPSKGGKDWRAGRCAGNNIIPASTGAAKAVGKVIPALNGKLTGMAIRVPTPDVSVVDLTCKLAKPASIEEIYQAVKEASNGPMKGIMGYTSDDVVSTDFIGCKYSSIFDKNACIALNDSFVKLISWYDNESGYSNRLVDLAVYVASRGL
Protein: Probable transposase (O33333)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Interaction partners:
- Possible resolvase
- Probable acyl-CoA dehydrogenase FadE21
- Probable resolvase
- Possible resolvase
- propanoyl-CoA C-acyltransferase
- Probable transposase
- Possible resolvase
- TIGR04338 family metallohydrolase
- Putative RNA-guided DNA endonuclease Rv2885c
- Possible resolvase
Sequence:
MAKFEIPEGWMVQAFRFTLDPTAEQARALARHFGARRKAYNWTVATLKADIDAWQATGIQTAKPSLRVLRKRWNTVKNDVCVNIETGVVWWPECSKEAYADGIDGAVDAYWNWQNSRSGKRDGKRMGFPRFKKKGRDPDRVTFTTGAMRVEPDRRHLTLPVIGTVRTHENTRRVERLIAKGRSRVLAITVRRNGTRIDASVRVLVQRPQQPKVTDPGSRVGVDVGVRRLATVATADGAVLERVPNPRPLDAALNELRHVCRARSRCTKGSRRYRERTTEISRLHRRVNDVRTHHLHCLTTHLAKTHGRIVVEGLDAAGMLRQQGLSGARARRRGLSDAALGTPRRHLSYKTGWYGSQLVVADRWFPSSKTCHVCGHVQEIGWAEHWQCDSCSASHQRDDCAAINLARYEDTSSVVGPVGAAVKRGADRKTRPGRAGGREARKGSSRKAAEQPRDGVQVA