wanglab/gogpt-training-data huggingface dataset:
Protein: DNA repair protein RecN (Recombination protein N) (P05824)
Organism: Escherichia coli (strain K12)
Function: May be involved in recombinational repair of damaged DNA.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21219465}. Note=In 70% of cell localizes to discrete nucleoid foci (probable DNA damage sites) upon treatment with mitomycin C (MMC) for 2 hours.
Interaction partners:
- Protein RecA
- LexA repressor
- Cell division inhibitor SulA
- Protein UmuD
- Holliday junction branch migration complex subunit RuvA
- DNA replication and repair protein RecF
- DNA polymerase IV
- Recombination protein RecR
- Single-stranded-DNA-specific exonuclease RecJ
- ATP-dependent DNA helicase RecG
Sequence:
MLAQLTISNFAIVRELEIDFHSGMTVITGETGAGKSIAIDALGLCLGGRAEADMVRTGAARADLCARFSLKDTPAALRWLEENQLEDGHECLLRRVISSDGRSRGFINGTAVPLSQLRELGQLLIQIHGQHAHQLLTKPEHQKFLLDGYANETSLLQEMTARYQLWHQSCRDLAHHQQLSQERAARAELLQYQLKELNEFNPQPGEFEQIDEEYKRLANSGQLLTTSQNALALMADGEDANLQSQLYTAKQLVSELIGMDSKLSGVLDMLEEATIQIAEASDELRHYCDRLDLDPNRLFELEQRISKQISLARKHHVSPEALPQYYQSLLEEQQQLDDQADSQETLALAVTKHHQQALEIARALHQQRQQYAEELAQLITDSMHALSMPHGQFTIDVKFDEHHLGADGADRIEFRVTTNPGQPMQPIAKVASGGELSRIALAIQVITARKMETPALIFDEVDVGISGPTAAVVGKLLRQLGESTQVMCVTHLPQVAGCGHQHYFVSKETDGAMTETHMQSLNKKARLQELARLLGGSEVTRNTLANAKELLAA
Protein: Large ribosomal subunit protein uL30 (60S ribosomal protein L7) (Q6Q417)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Large ribosomal subunit protein eL6
- Small ribosomal subunit protein uS4
- Large ribosomal subunit protein uL29
- Small ribosomal subunit protein uS14
- Large ribosomal subunit protein uL2
- Ribosomal protein L3
- Large ribosomal subunit protein eL21
- FAU ubiquitin-like and ribosomal protein S30 fusion a ubiquitously expressed
- Large ribosomal subunit protein eL19
- 40S ribosomal protein S15
Sequence:
MAGETKKKIPSVPESLLKRRQRFAAIRAVRLKKAKADKKASKVTRKLIFKRAEAYHKEYKQLYRREIRMSRMARKAGNYYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGVFVKLNKASINMLRIAEPYIAWGYPNLKSVRELIYKRGFGKIKKQRIALTDNSLIEKTLGQCGIICIEDLIHEIYTVGKNFKAANNFLWPFKLSSPRGGMNKKTTHFVEGGDAGNREDQINRLVRRMN
Protein: HTH-type transcriptional repressor KstR (P96856)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Controls the expression of genes used for utilizing diverse lipids as energy sources.
Interaction partners:
- HTH-type transcriptional repressor KstR2
- 3-ketosteroid-9-alpha-monooxygenase, oxygenase component
- Acyl-CoA dehydrogenase FadE34
- Iron-dependent extradiol dioxygenase
- Flavin-dependent monooxygenase, oxygenase subunit HsaA-triene-9,17-dione 4-hydroxylase, oxygenase subunit)-triene-9,17-dione monooxygenase)
- 3-oxo-4,17-pregnadiene-20-carboxyl-CoA hydratase beta subunit
- Possible lipid transfer protein or keto acyl-CoA thiolase Ltp4
- Medium/long-chain-fatty-acid--CoA/3-oxocholest-4-en-26-oate--CoA ligase
- 3-oxosteroid 1-dehydrogenase
- 3-oxo-4,17-pregnadiene-20-carboxyl-CoA hydratase alpha subunit
Sequence:
MSSANTNTSSAPDAPPRAVMKVAVLAESELGSEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVGTLYRYFPSKVHLLVSALGREFSRIDAKTDRSAVAGATPFQRLNFMVGKLNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDSMFARAMANGEPTEDQYHIARVISDVWLSNLLAWLTRRASATDVSKRLDLAVRLLIGDQDSA
Protein: Major tegument protein (MTP) (Protein p140) (P03179)
Organism: Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4)
Function: Tegument protein that plays a role in the inhibition of host intrinsic defenses to promote viral early gene activation. Interacts with host DAXX and thereby disrupts the complex between DAXX and ATRX. Suppresses the DAXX-ATRX dependent deposition of histone H3.3 on viral chromatin allowing viral transcription. Targets also host SMC5/6 for proteasomal degradation in a CUL7 and calpain-dependent manner to support nuclear membrane-less replication compartment formation and lytic virus replication.
Subcellular location: Virion tegument {ECO:0000269|PubMed:15534216}. Host nucleus {ECO:0000269|PubMed:22102817}. Note=Colocalizes with host DAXX at PML nuclear bodies. {ECO:0000269|PubMed:22102817}.
Interaction partners:
Sequence:
MEERGRETQMPVARYGGPFIMVRLFGQDGEANIQEERLYELLSDPRSALGLDPGPLIAENLLLVALRGTNNDPRPQRQERARELALVGILLGNGEQGEHLGTESALEASGNNYVYAYGPDWMARPSTWSAEIQQFLRLLGATYVLRVEMGRQFGFEVHRSRPSFRQFQAINHLVLFDNALRKYDSGQVAAGFQRALLVAGPETADTRPDLRKLNEWVFGGRAAGGRQLADELKIVSALRDTYSGHLVLQPTETLDTWKVLSRDTRTAHSLEHGFIHAAGTIQANCPQLFMRRQHPGLFPFVNAIASSLGWYYQTATGPGADARAAARRQQAFQTRAAAECHAKSGVPVVAGFYRTINATLKGGEGLQPTMFNGELGAIKHQALDTVRYDYGHYLIMLGPFQPWSGLTAPPCPYAESSWAQAAVQTALELFSALYPAPCISGYARPPGPSAVIEHLGSLVPKGGLLLFLSHLPDDVKDGLGEMGPARATGPGMQQFVSSYFLNPACSNVFITVRQRGEKINGRTVLQALGRACDMAGCQHYVLGSTVPLGGLNFVNDLASPVSTAEMMDDFSPFFTVEFPPIQEEGASSPVPLDVDESMDISPSYELPWLSLESCLTSILSHPTVGSKEHLVRHTDRVSGGRVAQQPGVGPLDLPLADYAFVAHSQVWTRPGGAPPLPYRTWDRMTEKLLVSAKPGGENVKVSGTVITLGEQGYKVSLDLREGTRLAMAEALLNAACAPILDPEDVLLTLHLHLDPRRADNSAVMEAMTAASDYARGLGVKLTFGSASCPETGSSASNFMTVVASVSAPGEFSGPLITPVLQKTGSLLIAVRCGDGKIQGGSLFEQLFSDVATTPRAPEALSLKNLFRAVQQLVKSGIVLSGHDISDGGLVTCLVEMALAGQRGVTITMPVASDYLPEMFAEHPGLVFEVEERSVGEVLQTLRSMNMYPAVLGRVGEQGPDQMFEVQHGPETVLRQSLRLLLGTWSSFASEQYECLRPDRINRSMHVSDYGYNEALAVSPLTGKNLSPRRLVTEPDPRCQVAVLCAPGTRGHESLLAAFTNAGCLCRRVFFREVRDNTFLDKYVGLAIGGVHGARDSALAGRATVALINRFPALRDAILKFLNRPDTFSVALGELGVQVLAGLGAVGSTDNPPAPGVEVNVQRSPLILAPNASGMFESRWLNISIPATTSSVMLRGLRGCVLPCWVQGSCLGLQFTNLGMPYVLQNAHQIACHFHSNGTDAWRFAMNYPRNPTEQGNIAGLCSRDGRHLALLCDPSLCTDFWQWEHIPPAFGHPTGCSPWTLMFQAAHLWSLRHGRPSE
Protein: Caspase A (EC 3.4.22.36) [Cleaved into: Caspase A subunit p16; Caspase A subunit p14] (G5EBM1)
Organism: Caenorhabditis elegans
Function: Cysteine protease which, in vitro, cleaves itself and caspase ced-3 into their mature active forms. Also cleaves, in vitro, inactive caspase csp-2 isoform b. Required maternally to induce apoptosis in a subset of cells fated to die during embryogenesis, mostly independently of the ced-9, ced-4 and ced-3 canonical apoptosis pathway. Involved in the degeneration of dopaminergic CEP neurons in response to high Mn(2+) levels.
Interaction partners:
- RING-type domain-containing protein
- Cell death protein 4
Sequence:
MVLKTIEDNCKSQFDDDLVEDFNNFQTTSSMSSSTTISTEDFNTIEIESTFEICRSGSYTEEPILGENDEFLIDFEMERFLKFLKDKTKQVEKRKEPFSQKEIYAVFQRRIKSELCIETVKKKFQPLLPNAIQTCEFDEETMIRMIYGAGIRIDSVDFWNRFTSKATISLDCYSRLISYSSDSLTLSGTHRSGFTYHWISTPPVTYHRTENKDPNIQEPSPVEFLDVQSSLGSSMKPPILDKPTKLDDPAETRHDCSYSLEEYDSQSRMPRTDAKKSNHKHKYCYEMNSNPRGTVLILSNENFKNMERRVGTKQDEVNLTKLFQKLQYTVICKRNLEAESMLEAIKEFAEMAHTDSIILFLLSHGDGAGSVFGIDDMPVNVMEVSTYLAYHQNLLLKPKWVAVSACRGGKLNMGVPVDGLPALEDKCAPISKFWNLMMSRIMPGTFTSLNADVIISFSTTDGFTSYRDEEAGTWYIKSMCKVFNKHSKTMHLLDILTETGRNVVTKYENVQGNVVLKQAPEILSRLTKQWHFSRSM
Protein: Photosystem II CP47 reaction center protein (PSII 47 kDa protein) (Protein CP-47) (P56777)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_01495}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01495}.
Interaction partners:
- Photosystem II reaction center protein J
- Photosystem II reaction center protein Z
- Photosystem II reaction center protein I
- Photosystem II reaction center protein L
- Photosystem II protein D1
- Cytochrome b559 subunit alpha
- Photosystem II reaction center protein H
- Photosystem II D2 protein
- Photosystem II reaction center protein K
- Chlorophyll a-b binding protein CP26, chloroplastic
Sequence:
MGLPWYRVHTVVLNDPGRLLAVHIMHTALVAGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITNSWGGWNITGGTITNPGLWSYEGVAGAHIVFSGLCFLAAIWHWVYWDLEIFCDERTGKPSLDLPKIFGIHLFLSGVACFGFGAFHVTGLYGPGIWVSDPYGLTGKVQPVNPAWGVEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRVSAGLAENQSLSEAWAKIPEKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAVGWLGHPVFRNKEGRELFVRRMPTFFETFPVVLVDGDGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGVSYSDPATVKKYARRAQLGEIFELDRATLKSDGVFRSSPRGWFTFGHASFALLFFFGHIWHGARTLFRDVFAGIDPDLDAQVEFGAFQKLGDPTTKRQAV
Protein: Histidine amino acid transporter (Q85V22)
Organism: Oryza sativa subsp. indica (Rice)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MAKQWWQDGRSAQEKAIDDWLPITSSRNAKWWYSAFHNVTAMVGAGVLSLPYAMSELGWGPGIAVLILSWIITLYTLWQMVEMHEMVPGKRFDRYHELGQHAFGEKLGLWIVVPQQLVVEVGVNIVYMVTGGKSLKKFHDVLCEGHGCKNIKLTYFIMIFASVHFVLSQLPNFNSISGVSLAAAVMSLSYSTIAWGASVDKGKVADVDYHLRATTSTGKVFGFFSALGDVAFAYAGHNVVLEIQATIPSTPEKPSKKPMWKGVVVAYIIVALCYFPVALVGYWAFGNHVDDNILITLSRPKWLIALANMMVVIHVIGSYQIYAMPVFDMIETVLVKKLRFPPGLTLRLIARTLYVAFTMFIAITFPFFGGLLGFFGGFAFAPTTYFLPCIMWLAIYKPRRFSLSWFTNWICIILGVMLMILSPIGGLRQIIIDAKTYKFYS
Protein: Nematode cuticle collagen N-terminal domain-containing protein (Q19079)
Organism: Caenorhabditis elegans
Interaction partners:
- Cuticle collagen dpy-2
- Cuticle collagen dpy-10
- Papilin
- Protein qua-1
- Protein unc-1
Sequence:
MEQKCAPRRSLRLLAIASATLAIVSMLATVIIVPLVYNHVQHLQSVMNSEVDFCKTRSRDLWREMVTVQSATGGIPARTARRTRRDNYGAQPIAANPPSSAAGSCCTCQVGPPGPPGPPGRDGRPGAPGRPGNPGPPGRDGALLPGPPPKPPCQKCPPGPPGPAGPPGPKGLPGPQGDAGTSGQDGVPGLPGPPGPSGPQGAPGVPGEKGPTGEPGKVINGAPPGPPGPPGPPGPQGPPGPPGKDGQPGKAGPPGLPGDPGEKGSDGLPGPHGGTGPRGPPGQPGSCDHCPPPRTGPGYARR
Protein: Ligand-gated cation channel ZACN (Ligand-gated ion channel zinc-activated 1) (Ligand-gated ion-channel receptor L2) (Zinc-activated channel) (Q401N2)
Organism: Homo sapiens (Human)
Function: Zinc-activated ligand-gated ion channel.
Subcellular location: Cell membrane {ECO:0000269|PubMed:16083862, ECO:0000269|PubMed:26872532}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Galanin receptor type 2
- Exocyst complex component 7
Sequence:
MMALWSLLHLTFLGFSITLLLVHGQGFQGTAAIWPSLFNVNLSKKVQESIQIPNNGSAPLLVDVRVFVSNVFNVDILRYTMSSMLLLRLSWLDTRLAWNTSAHPRHAITLPWESLWTPRLTILEALWVDWRDQSPQARVDQDGHVKLNLALATETNCNFELLHFPRDHSNCSLSFYALSNTAMELEFQAHVVNEIVSVKREYVVYDLKTQVPPQQLVPCFQVTLRLKNTALKSIIALLVPAEALLLADVCGGLLPLRAIERIGYKVTLLLSYLVLHSSLVQALPSSSSCNPLLIYYFTILLLLLFLSTIETVLLAGLLARGNLGAKSGPSPAPRGEQREHGNPGPHPAEEPSRGVKGSQRSWPETADRIFFLVYVVGVLCTQFVFAGIWMWAACKSDAAPGEAAPHGRRPRL
Protein: A-kinase anchor protein 14 (AKAP-14) (TAKAP-1.2) (Testis-specific A-kinase-anchoring protein TAKAP-80) (O35817)
Organism: Rattus norvegicus (Rat)
Function: Binds to type II regulatory subunits of protein kinase A and anchors/targets them.
Subcellular location: Cytoplasm {ECO:0000305}. Note=In fibrous sheath from epididymal sperm.
Interaction partners:
- cAMP-dependent protein kinase type II-alpha regulatory subunit
- cAMP-dependent protein kinase catalytic subunit beta
- cAMP-dependent protein kinase catalytic subunit alpha
- 5'-AMP-activated protein kinase subunit beta-2
- cAMP-dependent protein kinase type I-alpha regulatory subunit
- cAMP-dependent protein kinase type II-beta regulatory subunit
Sequence:
MNNKKKPPNQKAKTVENTSTAKAKKPEAPEPKNVTEPKDSKAVEDPKKSVTNQKEKKTVTIIADPKDKKSVTEPKEKKTVTISDPKDKKPVIEKDKRTVTFVTDVKDKRIVTDTKENRIASIDTKEKGPVVPEVKEKKVQLIDPKEKVVAPVAPVAPVAHAAQVPHAAQVPHAVQVPHAVPVAHAAPVAHTAQVSHAAPVAPSLPVVPPAPVVPLAPVVPPAPVAHTEPVAHAVPFAPPAPVAPPASVAPPVPDAPVALVAPVAPQVKQKIRVSEVKRKKEVPPRVPQLKEMKVVLFTPEIKEKKVVSEIKEKTQVIDGKEKLIVPDVKEKKPAVVEKKDERMNEIARTVVEGVLAASVQFVEEARNPIKNIKWLTHGEFTAEKGRKQIEKFVSTWEFQNRWVYYADFIEKKDLIHSFHYIYRVRWSAPTAVRPMARVSANAYFTIKFNKSKPADMPVDVSYIFENSELLQRPGKIRFREQWLRDITETKHILLESIPFKVV
Protein: histidine kinase (EC 2.7.13.3) (E0TZB4)
Organism: Bacillus spizizenii (strain ATCC 23059 / NRRL B-14472 / W23) (Bacillus subtilis subsp. spizizenii)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
Sequence:
MNKVGFFRSIQFKITLIYVLLIIIAMQIIGVYFVNQVEKSLISSYEQSLNQRIDNLSYYIEQEYKSDNDSTVIKDDVSRILNDFTKSDEVREISFVDKSYEVVGSSKPYGEEVAGKQTTDLIFKRIFSTKQSYLRKYYDPKSKIRVLISAKPVMTENQEVVGAIYVVASMEDVFNQMKTINTILASGTGLALVLTALLGIFLARTITHPLSDMRKQAMELAKGNFSRKVKKYGHDEIGQLATTFNHLTRELEDAQAMTEGERRKLASVIAYMTDGVIATNRNGAIILLNSPALELLNVSRETALEMPITSLLGIQENYTFEDLVEQQDSMLLEIERDDELTVLRVNFSVIQREHGKIDGLIAVIYDVTEQEKMDQERREFVANVSHELRTPLTTMRSYLEALAEGAWENKDIAPRFLMVTQNETERMIRLVNDLLQLSKFDSKDYQFNREWIQIVRFMSLIIDRFEMTKEQHVEFIRNLPDRNLYVEIDQDKITQVLDNIISNALKYSPEGGHVTFSIDVNEEEELLYISVKDEGIGIPKKDVEKVFDRFYRVDKARTRKLGGTGLGLAIAREMVQAHGGDIWADSIEGKGTTITFTLPYKEEQEDDWDEA
Protein: Peroxisomal carnitine O-octanoyltransferase (COT) (EC 2.3.1.137) (P11466)
Organism: Rattus norvegicus (Rat)
Function: Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate.
Subcellular location: Peroxisome {ECO:0000305}.
Interaction partners:
- Trifunctional enzyme subunit beta, mitochondrial
- Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
Sequence:
MENQLAKSIEERTFQYQDSLPPLPVPSLEESLKKYLESVKPFANEDEYKKTEEIVQKFQDGVGKTLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQLNVNFVGPSPHFEHYWPAREGTQLERGSILLWHNLNYWQLLRREKLPVHKSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFKTESEGHCPTHIAVLCRGRAFVFDVLHDGCLITPPELLRQLTYIYQKCWNEPVGPSIAALTSEERTRWAKAREYLIGLDPENLTLLEKIQSSLFVYSIEDTSPHATPENFSQVFEMLLGGDPAVRWGDKSYNLISFANGIFGCSCDHAPYDAMLMVNIAHYVDEKLLETEGRWKGSEKVRDIPLPEELAFTVDEKILNDVYQAKAQHLKAASDLQIAASTFTSFGKKLTKKEALHPDTFIQLALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQDPSASLLERQQKMLDAFAKHNKMMRDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNFVLSTSLVGYLRIQGVVVPMVHNGYGFFYHIRDDRFVVTCSSWRSCLETDAEKLVEMIFHAFHDMIHLMNTAHL
Protein: Indole glucosinolate O-methyltransferase 4 (EC 2.1.1.-) (Q9LPU8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in indole glucosinolate biosynthesis. Catalyzes methoxylation reactions of the glucosinolate indole ring. Converts the hydroxy intermediates 4-hydroxy-indol-3-yl-methylglucosinolate (4OH-I3M) and 1-hydroxy-indol-3-yl-methylglucosinolate (1OH-I3M) to 4-methoxy-indol-3-yl-methylglucosinolate (4MO-I3M) and 1-methoxy-indol-3-yl-methylglucosinolate(1MO-I3M), respectively.
Interaction partners:
- Protein trichome birefringence-like 19
- Cytochrome P450 81F4
- Cytochrome P450 81F3
- Cytochrome P450 81F2
Sequence:
MGYLLEETLSSNSKTPIVIDDDNELGLMAVRLANAAAFPMVLKAALELGVFDTLYAEASRSDSFLSPSEIASKLPTTPRNPEAPVLLDRMLRLLASYSVVKCGKVSEGKGERVYRAEPICRFFLKDNIQDIGSLASQVIVNFDSVFLNTWAQLKDVVLEGGDAFGRAHGGMKLFDYMGTDERFSKLFNQTGFTIAVVKKALEVYQGFKGVNVLVDVGGGVGNTLGVVASKYPNIKGINFDLTCALAQAPSYPGVEHVAGDMFVDVPTGDAMILKRILHDWTDEDCVKILKNCWKSLPESGKVVVIELVTPDEAENGDINANIAFDMDMLMFTQCSGGKERSRAEFEALAAASGFTHCKFVCQAYHCWIIEFCK
Protein: IP12282p (Q9VBT4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- CCR4-NOT transcription complex subunit 11
- CCR4-NOT transcription complex subunit 10
Sequence:
MEGKNIEYNADELQAPAWLNAQFIGDILREYEQLPDLKVTDLQVSPATAQGDHYASVMFRTKVEYTTPKGKFFKPLIIKTMPEQEGHKKDMLSESHLFETEIGMYCHALPEFERILREAGDNTKLFVPCIYHSLKPRQVMIFEDLVPQGYTVIRDSPPSLGDLKLAFDKLAKWHAVSMKVINEQPYFLKEFQYGLFEMPTIDTDPFITTGMTNFIEMLDKMPELRKYKHHFEKIKDNYMQRLEVEMHEYHKYRRNDRYYVLCHGDFHLRNMMFRHNKELGAYDDVMLVDFQLSNLCPITVDLTYSVYMLMEPEQRWEMGENLINEYFSVLVATLRKIGYKGDMPTQRELWEQIQNNKYYDFFLISTFLPIMVGVKSNDLKMHEALQDSQARLKSYFLDDYVQDVYKLLTKYEQLGYFKDL
Protein: Transmembrane protein 87B (Q96K49)
Organism: Homo sapiens (Human)
Function: May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN).
Subcellular location: Golgi apparatus membrane {ECO:0000305|PubMed:26157166}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Fibulin-7
Sequence:
MVAACRSVAGLLPRRRRCFPARAPLLRVALCLLCWTPAAVRAVPELGLWLETVNDKSGPLIFRKTMFNSTDIKLSVKSFHCSGPVKFTIVWHLKYHTCHNEHSNLEELFQKHKLSVDEDFCHYLKNDNCWTTKNENLDCNSDSQVFPSLNNKELINIRNVSNQERSMDVVARTQKDGFHIFIVSIKTENTDASWNLNVSLSMIGPHGYISASDWPLMIFYMVMCIVYILYGILWLTWSACYWKDILRIQFWIAAVIFLGMLEKAVFYSEYQNISNTGLSTQGLLIFAELISAIKRTLARLLVIIVSLGYGIVKPRLGTVMHRVIGLGLLYLIFAAVEGVMRVIGGSNHLAVVLDDIILAVIDSIFVWFIFISLAQTMKTLRLRKNTVKFSLYRHFKNTLIFAVLASIVFMGWTTKTFRIAKCQSDWMERWVDDAFWSFLFSLILIVIMFLWRPSANNQRYAFMPLIDDSDDEIEEFMVTSENLTEGIKLRASKSVSNGTAKPATSENFDEDLKWVEENIPSSFTDVALPVLVDSDEEIMTRSEMAEKMFSSEKIM
Protein: Chronophage, isoform I (R9PY46)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MRIKMPAVRIAQDSDSTENDAVATQDILTCGACQKAFALSDIVKFIQHKVLQCNKENYGQCATQNPQMDRDAEEGRPLSLVNRRPSISAPISGRKSAPASAAAAVAAAAAAAAAAAAASSTASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKDSETGATTLDSNAAPSSPAAIERQSSGDSSCEMEEQQDRQDKQSQPKQAKVKQEPYDEEGVNHHQNQDDDDDEEMEERSLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVESPGGGATLTVATPAALNNSALALAAAAAAASASGLASPQPAVSPNPAVTSSAKRSSPLGAAGSTILSTSVSSTCSNSLVNTSGGSISNTSSIGSPQQQQLQLQQQQAQQQQQRVQQQQRENLASAMAAGMRHHPLLPPPEAMHANPFQLLRMPLPPALAQAGNVVPTVAPLFGRPSPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNANGQVVGGVVSGSGEPRPPSSSSSGSQRGSVPPAALPPPSLSSQQQQQQQQAVQQQQQQGAQQQLQSAQQQQQSQQQSQQQQQITPGLVGGAGGSLKLEPQQMDFYSQRLRQLAGTTSPGAGSTVNSSSPSPRQKQSPHFASPSPSQQQQQQLATIPRPHSLTPPEKLGDASSENGSLGLILASTPRSASTPPSKTGDVSLQEPIAHCYSCSYCDKKFRFENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPADDQDNQDNQDDGSNADSLETNEADNDEDPNPDESEEELGDGDNDPDGDGDLDGEDEDEDELEECEDMDYKAEDLSVSNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAAAAAAAAAADNNNRGGAGAPLSDKLNGLPVAALRLRDEFAKNCNMFQQPQDGGAPSQVPLFNPFPNPFELSKRMKMDGGDWWGMSQALHRNEALFENLKLKPLGLGGANSLIQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAANAVAAAQAAQAAAQHIQAAAQQAQAVQAQAVQAQAAQQSQQQQQQLSPMGVVGYPPQFVSGHNLSLPGSVSGDNDSNASSSMTGVHPISLKEEA
Protein: Endophilin-A2 (Endophilin-2) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1) (SH3p8) (Q62419)
Organism: Mus musculus (Mouse)
Function: Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Early endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell projection, podosome {ECO:0000250}. Note=Associated with postsynaptic endosomes in hippocampal neurons. {ECO:0000250}.
Interaction partners:
- Synaptojanin-1
- Synaptojanin-2
- E3 ubiquitin-protein ligase CBL
- Endophilin-A1
- Endophilin-A3
- E3 ubiquitin-protein ligase CBL-B
- E3 ubiquitin-protein ligase CBL-C
- Activity-regulated cytoskeleton-associated protein
- Epidermal growth factor receptor substrate 15
- Programmed cell death 6-interacting protein
Sequence:
MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKDMEKKVDVTSKAVAEVLVRTIEYLQPNPASRAKLTMLNTVSKIRGQVKNPGYPQSEGLLGECMVRHGKELGGESNFGDALLDAGESMKRLAEVKDSLDIEVKQNFIDPLQNLCDKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILEELADKLKRRVREASSRPKREFKPRPREPFELGELEQPNGGFPCAPAPKITASSSFRSSDKPIRMPSKSMPPLDQPSCKALYDFEPENDGELGFREGDLITLTNQIDENWYEGMLHGQSGFFPLSYVQVLVPLPQ
Protein: Breast carcinoma-amplified sequence 1 homolog (Protein whose mRNA is enriched in synaptosomes 2) (Pmes-2) (Q3ZB98)
Organism: Rattus norvegicus (Rat)
Function: Required for myelination.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16133941}.
Interaction partners:
- RNA helicase
- Glycerophosphocholine cholinephosphodiesterase ENPP6
Sequence:
MGNQMSVPLRPGDQEHDPEADTYKVTSDNECVQNGIPVVVSTRVIQHYEEVDLGINSLKDNVPASSPETMEAHAVADASGKNLGKGSKPKAPAARSHFFLTLSRPVPGRPGDQGTDSSAASGRLDVSPGTAPENKDPSEHGALPVAAAPGPAPDKTPGCTEAKQQTLPATSPLAPSPPESQAEAPSRPKDFSFLNRLFKLDKGRESAPADSPPEEGKGSKSQERAIEAPAVPGNPHGVSAGKDIVDSEERKQEVDTLSYSVPADPEVLGTTKEDPQVVDATENSNSIMSFFKTLVSPNKTETKKDPEDTDAENSPTTPANLKSDKADLTPQETQGTAKSSKGSSQPGQAPSAGTSDTAREGGKEKAGPTSLPLGKLFWKKSVKEDSLSTGAEENAVCEPPVETVRLEEVESTLQTVDLTEKETQTEPTDVKVKEESKPRRTPLMAFLRQMSVRGSEGITRSEESNGKDSSCQTSNSTEKTPSPPEPEPAGTAQKNKETSSKDKKSVDKKSAAESNKQKNGKPEAREPAPCVQQPTVEVNALQTGDKTPKRSEKRRQSLGGFLKGLGPKRMLDAQVQTDPVSIGPVGKSK
Protein: Serine hydroxymethyltransferase (EC 2.1.2.1) (A0A8I5ZKU9)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MAERDATVWASHEKMLTQPLKESDAEVYSIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYHLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVYPDTGYINYDQLEENASLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVRSVDPKTGEETYYELESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTTEFKIYQLQVLANCRALSDALTELGYKIVTGGSDNHLILMDLRPKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKIAHFIHRGIELTLQIQSHMTMRATLKEFKEKLTGDEKFQSAVAALREEVENFASNFSLPGLPDF
Protein: Probable beta-1,3-galactosyltransferase 14 (EC 2.4.1.-) (Q8L7M1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal glycosyl residue.
Subcellular location: Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- F-box protein At3g49510
- Xyloglucan 6-xylosyltransferase 1
- DNA
Sequence:
MHSPRKLFHARSSLATRRSTALVVLTSLAIGIAGFTFGLAVILIPGLRLTGRNCLTNTPPKTVRVVWDVAGNSNGVVSGEKKRHKVMGFVGIQTGFGSAGRRRSLRKTWMPSDPEGLRRLEESTGLAIRFMIGKTKSEEKMAQLRREIAEYDDFVLLDIEEEYSKLPYKTLAFFKAAYALYDSEFYVKADDDIYLRPDRLSLLLAKERSHSQTYLGCLKKGPVFTDPKLKWYEPLSHLLGKEYFLHAYGPIYALSADVVASLVALKNNSFRMFNNEDVTIGAWMLAMNVNHENHHILCEPECSPSSVAVWDIPKCSGLCNPEKRMLELHKQESCSKSPTLPSDDE
Protein: EGF-containing fibulin-like extracellular matrix protein 1 (Extracellular protein S1-5) (Fibrillin-like protein) (Fibulin-3) (FIBL-3) (Q12805)
Organism: Homo sapiens (Human)
Function: Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:35998264}. Note=Localizes to the lamina propria underneath the olfactory epithelium. {ECO:0000250|UniProtKB:O35568}.
Interaction partners:
- Metalloproteinase inhibitor 3
- Epidermal growth factor receptor
- Complement factor H
- Microfibril-associated glycoprotein 4
- Fibulin-2
- Extracellular matrix protein 1
- Fibulin-1
Sequence:
MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTNECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF
Protein: Melanophilin (Exophilin-3) (Leaden protein) (Slp homolog lacking C2 domains a) (SlaC2-a) (Synaptotagmin-like protein 2a) (Q91V27)
Organism: Mus musculus (Mouse)
Function: Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor protein MYO5A.
Subcellular location: Melanosome.
Interaction partners:
- Ras-related protein Rab-27A
- Unconventional myosin-Va
- Ras-related protein Rab-27B
- RILP-like protein 2
- Synaptotagmin-like protein 2
- Unconventional myosin-VIIa
- Tyrosinase
- Ras-related protein Rab-3A
Sequence:
MGKRLDLSTLTDEEAEHVWAVVQRDFDLRRREEERLQGLKGKIQKESSKRELLSDTAHLNETHCARCLQPYRLLLNSRRQCLECSLFVCKSCSHAHPEEQGWLCDPCHLARVVKIGSLEWYYQHVRARFKRFGSAKVIRSLCGRLQGGGGSEPSLEEGNGDSEQTDEDGDLDTEARDQPLNSKKKKRLLSFRDVDFEEDSDHLVQPCSQTLGLSSVPESAHSLQSLSGEPYSEDTTSLEPEGLEETGARALGCRPSPEVQPCSPLPSGEDAHAELDSPAASCKSAFGTTAMPGTDDVRGKHLPSQYLADVDTSDEDSIQGPRAASQHSKRRARTVPETQILELNKRMSAVEHLLVHLENTVLPPSAQEPTVETHPSADTEEETLRRRLEELTSNISGSSTSSEDETKPDGTFLGGSPKVCTDTGHMETQERNPRSPGNPARPTKSTDEELSEMEDRVAMTASEVQQAESEISDIESRIAALRAAGLTVKPSGKPRRKSGIPIFLPRVTEKLDRIPKTPPADPDDQAKMPKATTAVPSLLRRKYSPSSQGVDSGSFDRKSVYRGSLTQRNPNGRRGTARHIFAKPVMAQQP