wanglab/gogpt-training-data huggingface dataset:
Protein: Two-component system response regulator (A0A0H2WNS4)
Organism: Salmonella paratyphi A (strain ATCC 9150 / SARB42)
Interaction partners:
Sequence:
MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLINHGDKVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLMIDESRFQASWCGKALDLTPAEFRLLKTLSLEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRLV
Protein: CLAVATA3/ESR (CLE)-related protein 19 (AtLLP1) (Protein EMBRYO SURROUNDING REGION 19) [Cleaved into: CLE19p] (Q8W261)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Extracellular signal peptide that regulates cell fate. Represses root apical meristem maintenance.
Subcellular location: [CLE19p]: Secreted, extracellular space {ECO:0000269|PubMed:16055633}.
Interaction partners:
- Protein CLAVATA 3
- CLAVATA3/ESR
- CLAVATA3/ESR
- CLAVATA3/ESR
- Receptor-like protein CLAVATA2
- CLAVATA3/ESR
- CLAVATA3/ESR
- CLAVATA3/ESR
- Carboxypeptidase SOL1
- CLAVATA3/ESR
Sequence:
MKIKGLMILASSLLILAFIHQSESASMRSLLMNNGSYEEEEQVLKYDSMGTIANSSALDSKRVIPTGPNPLHNR
Protein: FLJ10613-like (Guanine nucleotide-binding protein-like 3 (nucleolar)-like) (Guanine nucleotide-binding protein-like 3-like protein) (Uncharacterized protein flj10613l) (Q7SZX9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Nucleolar GTP-binding protein 2
- Nucleolar GTP-binding protein 1
- Pescadillo
- Ribosome assembly factor mrt4
- NOC2-like nucleolar-associated transcriptional repressor
- MKI67 FHA domain-interacting nucleolar phosphoprotein
- Ribosomal L1 domain-containing protein 1
- RNA helicase.
- Protein SDA1 homolog
- Ribosome production factor 2 homolog
Sequence:
MSKAKQKRAKRLGFCGKKPKDGTQSHGGKKDPGVPNVRSFKEHSQRQAELRKQRLEEQQERQRLSREKEMMKRRSLDSYQKDIQLRQREFEQREIQMQNLEKHVNFETENSRKAYCREFKKVIEAADVILEVLDARDPLGCRCPQVEQAVVQSGTNKKIVLVLNKIDLVSKDIVEKWIKYLRNEFPTVAFKSSTQQQNKNLKRSRVPVTQATQELLESSACVGADCLMKLLGNYCRNQDIKTAITVGVVGFPNVGKSSLINSLKRARACNVGATPGVTKCLQEVHLDKHIKLLDCPGIVMATSTSDAAMILRNCVKIEQLVDPLPAVEAILRRCNKMQIIDHYGIPDFQTAHEFLALLARRQGKLRKGGLPDSDKAAKSVLMDWTGGRISYFTHPPETHTLPTHVSAEIVAEMGKAFDWDELEKGNLEALAECGTSDVQMGFCMATSGLTQGGQGEDLAELQMDEPLDDPELQDKVELMDADEDPEFGPMTVELKVPKTKSGVVEAVGPKPVDLKDILDIDPLLQGQALQAANKKRKKQQKRADKLGTKLSDSLTAALNFSFSDS
Protein: [histone H3]-trimethyl-L-lysine(4) demethylase (EC 1.14.11.67) (B0S6L0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- Euchromatic histone-lysine N-methyltransferase 2.
- ATP synthase subunit gamma.
- ATP synthase F
- ATP synthase F1 subunit delta.
- ATP synthase subunit alpha
- ATP synthase peripheral stalk subunit OSCP, mitochondrial
- Lysine-specific demethylase phf2
- Histone lysine demethylase PHF8
- Histone deacetylase 1
- Lysine-specific histone demethylase
Sequence:
MMDVGEEFVPPPECPVFEPSWEEFADPLGYIAKIRPIAEKSGICKIRPPPDWQPPFAVEVDNFHFTPRIQRLNELEAETRVKLNYLDRIAKFWEIQGSSLKIPNLERRILDLFSLAKIVTEEGGFESVSKERRWARVAQKLGYPPGKNIGSLLRSHYERIVYPFELFQSGASLPPRKPRQYDSDEVDREYKPHSIPLRQSVPPSKMSSYGRRANRLQPEGPEDPTHHPLTTGSQHISSPEPTEEDIEKNPELKKLQIYGAGPKMMGLGLVPRDKTRKKDDLPQTVIVRDSAVKDEPAETAVTKSDPDIPPPPPNLIIKEDVDDDKSHIDKPNDPSDEPCTKMTMRLRRNLNNPQFVDSFVCRMCGRGDEDEKLMLCDGCDDNYHTFCLIPPLTDPPKGNWRCPKCVAEECKKPSEAFGFEQATREYTLQSFGEMADTFKADYFNMPVHMVPTELVEKEFWRLVSSIEEDVTVEYGADIHSKEFGSGFPVNNGKRQLSEEEEEYARSGWNLNVMPVLEQSLLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKTWYGVPCSAAEKLEEVMKKLTPELFEFQPDLLHQLVTIMNPNILMSHGVPVVRTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPTGRSCIEHYRQLRRYCVFSQEELTCKMAACPEKLDLNLAAATHREMFIIVQEERKLRKSLLERGIKEAEREAFELLPDDERQCDKCKTTCFLSALACSNCPERLVCLYHAQDLCSCPSEKLYLRYRYTLDELLAMLHRLKVRAESFDSWANRVKEALEQDEGNKIDIKDLEVLKEEAADKKFPNNELLQRLNTVFVDIEKCESCSTELLSNSQSSRMTLKELKTLVDTMQNLPCVIKQQDEVQLILQKIEEFDSRAQVLVDSTKSEWKQDSPLPVATEIQALLEEGASLPVIAPACELLSGLLEQGRWLGEVRRTLGPEGSEVTLTVLRNLMESGCNVPQSVSVETAMAELQELLTIAERWEEKAQICLEDRQKHHLSTLEAIVNEAQLIPVQLPNILSLQACLSRARAWVTDLEEIQNGEHYPCLDDLEGLVAIGRDLPVKMEELKQLELQVASAHSWREKASKTFLKKNSQHSLLEVLCPCVEKSKKMEDNSMVTEADSDVNVLGLTAQDLRDPGAIVMAFKEGERLEKEALLRLQQVNLAKPSIENGVSTDQDSIKTEKKQSNSMETDVPLNSDSPVLQNGGSSHSLTSSQTVCICGGPPRPLLHRCHLCKDWFHGGCVSFPPLLATSDTHLTKPLCWWDWNTRFLCPRCQRSRRPRLETILALLVALQRLPVRLPEGEALQCLTERAINWQGRAKQALDTPEVQEALDRLQQVEDEMVSIKEEEPEEKKKWNGDAVIVLSDSEEAEDGVIDLTEDGNSPKKNERNAVNGTQSGCENGIGRKSSAHEVTGVESLLSLVPSLKGPVVELNTSVRAQLEELQLEGDLLEVTLDQTHAIYRILQASSQPPQDTLRTLIQIELQEQRSSGRGNKSKDSKRKRKSQKTEGEPKSTEASDCKKTKALNLSPPTDTHTDVVMFS
Protein: Inner kinetochore subunit WIP1 (CENP-W homolog) (Constitutive centromere-associated network protein WIP1) (W-like protein 1) (Q2V2P8)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.
Subcellular location: Nucleus {ECO:0000305|PubMed:22561346}. Chromosome, centromere, kinetochore {ECO:0000305|PubMed:22561346}.
Interaction partners:
- Inner kinetochore subunit CNN1
- Inner kinetochore subunit CTF3
- Inner kinetochore subunit MCM16
- Inner kinetochore subunit MCM22
- Inner kinetochore subunit AME1
- Inner kinetochore subunit NKP1
- Inner kinetochore subunit OKP1
- Inner kinetochore subunit NKP2
- Inner kinetochore subunit CHL4
- Inner kinetochore subunit IML3
Sequence:
MDTEALANYLLRQLSLDAEENKLEDLLQRQNEDQESSQEYNKKLLLACGFQAILRKILLDARTRATAEGLREVYPYHIEAATQAFLDSQ
Protein: RNA methyltransferase family protein (RNA methyltransferase-like protein) (Q9LU28)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Ribosome biogenesis protein BOP1 homolog
- tRNA
- Protein TORMOZ EMBRYO DEFECTIVE
- Ribosome production factor 2 homolog
- U3 small nucleolar RNA-associated protein 18 homolog
Sequence:
MLAATPAHGLRYVVVPTRSWLHRFRCCSSSLAPLSPSEFSGGNKAQKKLNDENNTNVSNEKTAPYYPKRGETVELVCESLGFKGKGICKVDGTGYVVMCDRALPGERFLGRVTRRKGSYAEVTKMKTISPHKDLVEAPCEYASYCGGCKTQNLSYEAQLRAKEEQVHELIRHVGRFSDNNPGLEIVLKPIVACDIQFHYRNKMEFSFGPQRWLPIEMLNERQDGPKNFALGLHAPGFFDKVLNVDKCLLQSEPGNLVLAAVQDCWRDPELSLSPYDCRSHVGFLKHLMLRTGRNVETGSLELMVNFVTSSYKPELLKPLVDRISSIPQVVSIMNNVNSSVGNTSVGEKEYTLYGKDTITEVLRGLTFQISANSFFQTNTHQAEVLYKLIEESAGLKGDGSEVVLDLFCGTGTIGLTLARRAKHVYGYEVVPQAITDAHKNAQINGIENATFIQGDLNKIGEDFGNNFPKPDIVISDPNRPGMHMKLIKFLLKLKSPRIIYVSCNPATCARDLDYLCHGVEEKNLKGCYKLMSVQPVDMFPHTPHIECVCLLELA
Protein: Kanadaptin (Q3UHY0)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MLGEDSDEEEEANTTEGKSSRSGQDDELGCTWGMGEDAVEDEAEENPIALDFQQDREAFYIKDPKKALQGFFDREGEELEYEFDEQGHGTWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMVQCSLEACRVLDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDIFLDRTGLVEKKRLNRMKKAGKLDEKPETFESLVAKLNDAERELAEISERLKASSKVLSEPSSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKLVKPAEIPELKKTELQTTNAENKTEKLALPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPALMQMKDEPEVEEEEEEEEEEEEKVKEEHEERVEDGGVRLLQEPELELEAAVEHPSAPSEPSCSKETKSHAAPANEYKQDRDEPKKKKSPGPGKFPPILSSKYPEDDPDYCIWVPPEGQSGDGRTHLNDKYGY
Protein: Probable glycosidase CRH1 (EC 3.2.-.-) (Congo red hypersensitive protein 1) (P53301)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Probable glycosidase that plays a role in cell wall architecture. Required for the transfer of chitin to 1,6-beta-glucan in the cell wall.
Subcellular location: Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI-CWP), localized particularly in chitin-rich areas. Found at the incipient bud site, around the septum area in later stages of budding, and in ascospore envelopes. Redistributes uniformly over the cell cortex upon heat stress.
Interaction partners:
- Congo red hypersensitive protein 2
- Cell wall mannoprotein PST1
- 1,3-beta-glucanosyltransferase GAS1
- Glucan 1,3-beta-glucosidase
- Cell wall protein CWP1
Sequence:
MKVLDLLTVLSASSLLSTFAAAESTATADSTTAASSTASCNPLKTTGCTPDTALATSFSEDFSSSSKWFTDLKHAGEIKYGSDGLSMTLAKRYDNPSLKSNFYIMYGKLEVILKAANGTGIVSSFYLQSDDLDEIDIEWVGGDNTQFQSNFFSKGDTTTYDRGEFHGVDTPTDKFHNYTLDWAMDKTTWYLDGESVRVLSNTSSEGYPQSPMYLMMGIWAGGDPDNAAGTIEWAGGETNYNDAPFTMYIEKVIVTDYSTGKKYTYGDQSGSWESIEADGGSIYGRYDQAQEDFAVLANGGSISSSSTSSSTVSSSASSTVSSSVSSTVSSSASSTVSSSVSSTVSSSSSVSSSSSTSPSSSTATSSKTLASSSVTTSSSISSFEKQSSSSSKKTVASSSTSESIISSTKTPATVSSTTRSTVAPTTQQSSVSSDSPVQDKGGVATSSNDVTSSTTQISSKYTSTIQSSSSEASSTNSVQISNGADLAQSLPREGKLFSVLVALLALL
Protein: Eukaryotic translation initiation factor 3 subunit D (eIF3d) (Eukaryotic translation initiation factor 3 subunit 7) (P30642)
Organism: Caenorhabditis elegans
Function: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03003}.
Interaction partners:
- Eukaryotic translation initiation factor 3 subunit I
- Eukaryotic translation initiation factor 3 subunit C
- Eukaryotic translation initiation factor 3 subunit G
- Eukaryotic translation initiation factor 3 subunit B
- Eukaryotic translation initiation factor 3 subunit H
- Eukaryotic translation initiation factor 3 subunit L
- Eukaryotic translation initiation factor 3 subunit F
- Eukaryotic translation initiation factor 3 subunit K
- Eukaryotic translation initiation factor 3 subunit A
- Eukaryotic translation initiation factor 3 subunit E
Sequence:
MALPKFELLSLADNTVGWGPLASSSSADEPVPFQQFNKADRIGRVADWIGVDRFYRRGNERYNERVYGSAANAGSQFDYIHGMDEHNFQLVDTSKPMARNPQRNFRVRQMHLRKMMQKENEKREMVNQSTNLRMKRSIAKEQQRAFKMWQRRGGNARQGQRGQGGRFGGDRPKERLPSVQVRPEWVVLEEMNLSAFSKLALPNIPGGDDIGDHQYGSLQYYDKTIDRVSVKNSIPLQRCAGVFYNVTTTEDPVIQELAQGGAGNVFGTDIILATLMTAPRSVYSWDIVAYRVGDKLFFDKRNTRDILNPVETLTVSETSAEPPSFDGNGINNAKDLATEAFYINQNFRRQVVKRNDAGFTFKNARAPFEDEETGESGTAYKYRKWNLGNGVDGKPVELVCRTELDGVIHGLGNETQTLTIKAFNEWDSTQSGGVDWRTKLDVQKGAVMATEIKNNSAKVAKWTLQALLAGSDTMKLGYVSRNNARSTQNHSILLTQYVKPTEFASNIALNMDNCWGILRCVIDSCMKQKPGKYLLMKDPQSPVIRLYSLPEGTFESERESSDEENSDDDQ
Protein: Mediator of RNA polymerase II transcription subunit 23 (Mediator complex subunit 23) (dSUR2) (dTRAP150) (Q9W1X7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). Required for transcriptional activation in response to heat shock.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Mediator of RNA polymerase II transcription subunit 1
- Mediator of RNA polymerase II transcription subunit 18
- Mediator of RNA polymerase II transcription subunit 15
- Mediator of RNA polymerase II transcription subunit 19
- Mediator of RNA polymerase II transcription subunit 12
- Mediator of RNA polymerase II transcription subunit 31
- Mediator of RNA polymerase II transcription subunit 4
- Mediator of RNA polymerase II transcription subunit 14
- Mediator of RNA polymerase II transcription subunit 17
- Mediator of RNA polymerase II transcription subunit 6
Sequence:
METQVIDTVNEFLKVDSLDEAFVSVIVFKPNTEQERATRFANDLVTAFGNVAQENREQVLRLYLLRAAGASGYHIKVLMAALVKLVDAHVITARMLCDKVLMCEKLDFEHRTFWIESFRLIKRVIVQVDYKGVREIMKVCRDKAQWFPLNVNVTYMPQLLAVEDILRFIFDRNNCLLPAYFIANEIMRPFPYHWKLNRLMTDFVEEFRTTAQMVSIIGHASMLPIVEHFGYADHMMNSWRLDHNTLKFNFKGSLPYEPELLEEQKPLLRYVLEQPYSREMVSQMLNLQKHQKQRYNALEEQLVNLIVQAMEMTEANDATAGSGFNSSDEQITPYEWMWLHLSSQLIYFVLFQFVSFMHIVLALHEKLSKLELRKGRDQLMWILLQFISGSIQKNPITNFLPVFRLFDLLYPELEPLKLPDINKSSMVRHMAPICVWIHLMKKARVENMNITRPLPIALKNHYDFLQHLVTANTMMNMTLGNDFRIILICNAYSTNQEYFGRPMGLLLDALNGTSKSPNGGQIPAVTFSVTVLDSLTVHSKMSLIHSFVTQMLKQAQSKGQVPAAALLETYARLLVYTEIESLGIKGFLSQLMPTVFKNHAWAMLHTLMEMFSYRLHHVPTHYRVQLLSLLHSLSSVPQTNKMQLNLCFESTALRLITSIGSAEFQPQFSRYFNDKSPGAVASNESEELNRVLILTLARSMHVHGGGDEMQGWCKDFLSNIIQHTPHSWPMHSLACFPPALNEYFTQNNQPPENKQQLKKAVEEEYRTWTSMTNENDIIAHFLRPTTNPLFLCLLFKIIWETENISPVAYKILEGISARALSTHLRKFCDYLVAEVASSSDGRDFIHKCVDTINNMIWKFNVVTIDRVVLCLALRTHEGNEAQVCFLIIQLLLLKASELRNRVQEFCKDNNPDHWKQSNWQDKHLSFHQKYPEKFALDESASQIPLPVYFSNVCLRFLPVLDVVVHRFIELTITNVHQILGFILDHLSILYKFHDRPITYLYNTLHYYERILRDRPALKKKLVGAITSAFSEIRPPNWSVSEPYKVYLQSQDSLWTPELSYYMSLIRRLADTISGKNVFYSTDWRFNEFPNAPTHALYVTCVELLGLPVAPPLVASNLIDVIVSGYAVIPQKDIHSYINAVGIVLAALPEPYWSGIYDRLQDMLNTPNMLNWTYRFNAFELFNFKTVREAMLEKTYAVVLAVAHSVFHHMGAFKLAAMTRYLKEKLKPCVRTEQQLLYLCHVFGPFLQRIELEKPNAVAGIAVLLYEILEIVDKHHGPKPLQYMDQICDFLYHIKYIHVGNIIKNESEAIIKRLRPLLQMRLRFITHLNLEDIHTEKINDNTSNNAITSQTQSPMQTQHQQQPQQPHQQQQQQQQQQQQQQQQQQQQQQMQQQQINAVQTTSVPLGSGGNLQQQQQINQQQQMYMQHMQQHQHMQNMRHN
Protein: Transcriptional enhancer factor TEF-4 (TEA domain family member 2) (TEAD-2) (Q15562)
Organism: Homo sapiens (Human)
Function: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.
Subcellular location: Nucleus.
Interaction partners:
- Transcriptional coactivator YAP1
- WW domain-containing transcription regulator protein 1
- Transcriptional enhancer factor TEF-1
- Transcriptional enhancer factor TEF-3
- Transcription cofactor vestigial-like protein 4
- Transcription factor 7-like 2
- Transcription factor 7-like 1
- Lymphoid enhancer-binding factor 1
- Transcription factor 7
- Homeobox protein notochord
Sequence:
MGEPRAGAALDDGSGWTGSEEGSEEGTGGSEGAGGDGGPDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLKDQVSKDKAFQTMATMSSAQLISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERGAQHHIYRLVRD
Protein: Glutathione gamma-glutamylcysteinyltransferase 2 (EC 2.3.2.15) (Phytochelatin synthase 2) (AtPCS2) (Q9ZWB7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the synthesis of phytochelatins (PC) and homophytochelatins (hPC), the heavy-metal-binding peptides of plants.
Interaction partners:
- Glutathione synthetase, chloroplastic
- TOM1-like protein 2
- Glutamate--cysteine ligase, chloroplastic
- Metallothionein-like protein 2B
- Putative metallothionein-like protein 1B
- Beta-glucosidase 27
- Metallothionein-like protein 1A
- LanC-like protein GCL2
- Thioredoxin domain-containing protein PLP3B
- Zinc finger protein ZAT6
Sequence:
MSMASLYRRSLSPPAIDFASFEGKQIFNEALQKGTMEGFFGLISYFQTQSEPAFCGLASLSMVLNSLSIDPGRKWKGPWRWFDESMLECCEPLEIVKDKGISFGKVVCLAHSSGAKVEAFRTNQSTIDDFRKYVVKCSTSDNCHMISTYHRQVLKQTGTGHFSPIGGYNAERDMALILDVARFKYPPHWVPLKLLWDAMDSIDQSTGRRRGFMLISRPHREPGLLYTLSCKDESWISIAKYLKEDVPRLVSSQHVDTIERILYVVFKSLPANFNQFIKWMAEIRRTEDVNQNLSSEEKSRLKLKQELLKQVQETKLFKHVDKFLSSVYEDNLPYVAAKVYCDGDEILSGYESDESCCKETCVKCIKGLGEEKVTVVAYPSGNDVFTALLLALPPQTWSGIKDQSLLQEMKQLISMVSHPTLLQQEVLHLRRQLEMLKRCQENKEDEELSAPA
Protein: Protein PIN-LIKES 3 (Auxin efflux carrier-like protein 3) (Q9C9K5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in cellular auxin homeostasis by regulating auxin metabolism. Regulates intracellular auxin accumulation at the endoplasmic reticulum and thus auxin availability for nuclear auxin signaling.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:22504182}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Amino acid transporter AVT1E
- Plant intracellular Ras-group-related LRR protein 8
- Probable aldo-keto reductase 6
- At2g41380
Sequence:
MVKLLELFITSSKPVVEILLITSVGFYMALDGVNLLGHDARKYLNNIVFYVFSPSLIGSRLADSVTYESLVKMWFMPVNVLLTFIIGSLLGWIVIVITKPPSHLRGLILGCCAAGNLGNMPLIIIPAVCKEKGGPFGDPESCQKYGMGYVALSMAMGSIYIWTYVYNLMRVLSNSPVETPPSVESNYDSYKVPLISSKEEENNQKAGRWEKVKRRLVSLSQKVNLKTIFAPSTIAAMIALVIGLITPLRKLIIGTEAPLRVLQDSVTLVGDGAVPAMTMIIGGNLLKGLRSSGMKMSSIIGVLVARYVLLPMSGVLIVRGAYKLDLVTSEPLYQFVLLLQYAVPPAMNLGTITQLFGTGESECSVIMLWTYSLASIALTVWPTFFMWLVA
Protein: Protein OPG036 (Protein N2) (P14357)
Organism: Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
Function: Plays a role in the inhibition of host innate immune response. Within the host nucleus, inhibits activation of interferon-beta promoter by inhibiting IRF3 activation.
Subcellular location: Host nucleus {ECO:0000269|PubMed:23761407}.
Interaction partners:
Sequence:
MTSSAMDNNEPKVLEMVYDATILPEGSSMDPNIMDCINRHINMCIQRTYSSSIIAILDRFLMMNKDELNNTQCHIIKEFMTYEQMAIDHYGGYVNAILYQIRKRPNQHHTIDLFKRIKRTRYDTFKVDPVEFVKKVIGFVSILNKYKPVYSYVLYENVLYDEFKCFINYVETKYF
Protein: Sorting nexin-18 (Sorting nexin-associated Golgi protein 1) (Q91ZR2)
Organism: Mus musculus (Mouse)
Function: Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane. Together with DNM2, involved in autophagosome assembly by regulating trafficking from recycling endosomes of phospholipid scramblase ATG9A.
Subcellular location: Endomembrane system {ECO:0000250|UniProtKB:Q96RF0}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q96RF0}; Cytoplasmic side {ECO:0000250|UniProtKB:Q96RF0}. Endosome membrane {ECO:0000250|UniProtKB:Q96RF0}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q96RF0}; Cytoplasmic side {ECO:0000250|UniProtKB:Q96RF0}. Recycling endosome membrane {ECO:0000250|UniProtKB:Q96RF0}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q96RF0}; Cytoplasmic side {ECO:0000250|UniProtKB:Q96RF0}. Cell membrane {ECO:0000250|UniProtKB:Q96RF0}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q96RF0}; Cytoplasmic side {ECO:0000250|UniProtKB:Q96RF0}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q96RF0}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q96RF0}; Cytoplasmic side {ECO:0000250|UniProtKB:Q96RF0}. Note=Localized at sites of endocytosis at the cell membrane. Detected on newly formed macropinosomes. Partially colocalized with clathrin and dynamin at the cell membrane. Transiently recruited to clathrin-coated pits at a late stage of clathrin-coated vesicle formation. {ECO:0000250|UniProtKB:Q96RF0}.
Interaction partners:
- Sorting nexin-9
- Dynamin-2
- Sorting nexin-33
- Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
Sequence:
MALRARALYDFKSENPGEISLREHEVLSLCSEQDIEGWLEGINSRGDRGLFPASYVQVIRAPEPGPPADGGPGAPARYANVPPGGFEPLPAAPPAAFPPLLQPQASPGSFQPPGAGFPYGGGALQPSPQQLYGGYQASLGSDDDWDDEWDDSSTVADEPGALGSGAYPDLDGSSSAGGGAAGRYRLSTRSDLSLGSRGVSAPPAPSVWSQELGHGEPQPQSLLHLRQVGRGGLRAGRGVRLREGWGQAVRGAGSYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQKGALTKVKESRRHVEEGKMEVQKADGIQDRCNTISFATLAEIHHFHQIRVRDFKSQMQHFLQQQIIFFQKVTQKLEEALHKYDSV
Protein: Uncharacterized transporter C417.10 (O94491)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:16823372}. Golgi apparatus {ECO:0000269|PubMed:16823372}. Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. Note=Barrier septum. Cell tip. {ECO:0000255, ECO:0000269|PubMed:16823372}.
Interaction partners:
Sequence:
MSSISIDEKLKDPESVQNKEILDVDVGDLSPKGVDAAFNYALDVDYDEIDPETERRLVRKIDCTIFPVMCLVYCIQFLDKTSNSYAVIMGLKEDLKMEGQMYSWSGTAFYLGYLVFEFPASLLLQRFPLSKTLCVFLVIWGFLLCMTSVANYPGFIALRVLLGMMESAASPGFILLTAQWYKRSEQQLRTSVWVAFNGLGQILGSCMAYGLAKRTSLPMRGWKLIFIICGVLAIFLGFVILAVVPDNPFKAWFLTEEDRKLVVKRLRANKQGVGNNHFKLYQFKETMLDIRTWIMFVSSVLLNIPNGGIGTFSSLLIKGTMGYDTLQTLLMGLPAGACEFGGLIAFGFLSLFIHKRMVLATITTCIALIGSCLLSFAGPPRAQLAGYYLLMVSPGAMIVMFAIISSNASGYTKKVTVGVIYLIGYCVGNLIGPQTFKAADAPEYMPAKNTMVGCYAATLVTFPALYYVNWRENKRRDQLAAEGKIEHRPNAEFEDLTDFENLDFRYTL
Protein: Stac-like, isoform I (A0A0B4KFR2)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane, sarcolemma {ECO:0000256|ARBA:ARBA00004278}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004278}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004278}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MGISAHAAPASFWNHPRRIRRTPTSDRDGVDQCRPWICRRKDRRPAHPAANRPPESRVCGPSSTFRWDDWAAPAPRTRERATDCARMCMCTSRIPYSVARICARTTSMHSSRPASRSSSFIRRPLTRRQRMAVGGVTRRLWRTMRVYTIHQGRGVRRARAAQAVAAYLRDRRARIGKGWPAQGHGVRISATEQWADKPVVRRPGDPTRRVAAGAVPVLAERLPKVTGSSVKSSSGRRSRRRRIFGWRGPRGGSLSPQGGSMASYNGVLKDYSHSSLNEAFKSQNNVNFKLIKTVSDFSETLSRLYEEHATALQVAVSNYRKKNAELRKERPACHLAIFQAWETFLQEVETDSQACNDVASVLSRQVSRPMLDKSFHRKVQSRKIFTHRESFETIIAKTEEKLSKCRVDYKQCHLAHRQNPSQHSLTEYIDAHNAYVQQLHATNGMLEAYHTDTLPQQMQELEEIHNDLVAIVSDSLMQGAEVIAGKANDQAKRYNSLSNQCAAVSPQQDLVNFVRLLAQPSQAQKIPRRLFASPQAEVGEEAGDHNEMTPCLRNELVFDRHSTLSQRSALESLKREAIELELQIRQLQDSIEALNRTQTRGIEGQLYNKVNELQEDLSMKKFDLRAKQIHLAAIRAQKDLFVSKVEPTSPRNERKFSAATAPSMKTKWLKAFKSLKPAGSGSAQQADSQPPRQNQMYHAVSTVLTLRRNGASSTASEPLRPNLDGSHHLQEYTYKKITACDVCSQILRGHTRQGLRCRICKLNAHGDCAPNLPRCQPKQKLLRRQKSTSELENRVDIEEETGADKSVQAKQMDGSVAGGSALPVPVLSERELGRAPPPDIPIVSVSELALQEQQQQQQQQQQQHQQQQRSLASVAQAAAVRAGRGVRPPPVAMPILGVQLQQQELQQQRGGLPVPSQDISSSSAPHSPRRQKLNLRMKSLSLDSPESSELHGQFRRRTQLPGTGASTSAGSGYYHGGSGGHLEHSTPPSNNSRLHSPSSPSHPGRKLLYATRGMRGGSVDLPDEMEKSQSSASTSPCLSPKTHRLLPTNLYVIIYNFKARHADELDLKAGYKVTVIDNSDPDWWKGKVLGRVGYFPSKYCVRLNANEKPLQVTHNLQVSDSERGENLTLLRDQIVIQTGDEVNGMVMIRAAEHGQGYCPIKYLQEVXQPEEDEPPSDERDRPHKSSMQTSSSRTADKTKRRIRIVVSENHNVAASSVAPAPPTTAFNTTTHHQIPRESDIETKRLNIDYGDEGSADWDKDREVLILSGRRNKNDKNWENWERIREQKLEKMKGICFESYRQSKRDKLLQAKPRPKQLDSTWYTDNIYSNRSDDMDEDYVPDCLKYGPFRTLRDIHELDEKSGVTEERRVEGEGSPGYGLHRSKSCKEFQYPKSQSWCFEGNVFEAGGGVASGSGSSSGAPPPTTSILKNRAGVPKSYSFSATTKTMPFDIIDYELPPVSNTRREKKEALRRNMNALCSSSLDRCCARDQCTSARCLLEDIYPGSRMRPRTTGAGSNRNLSAADWLFEERAGRQRTPAAPTVICCCSAAEDCCCHRQRQQQPPLPARPRSRPLCPGHHPAAEEEEHMHCRYDTDLEHFIRAERERLMLQDKFLDDDERYLAAAPAPRSPGRRYPAGNYHRPPRSKSLLEMQPPTILYDEDTCSDTTEIDLEDFNIDLEKYWEQLDKPPSPINMDMRRNMHSSLKVKNVNVRCYNNGQPIDLHDREHERLMIKKSLLEGMPSPPQLDSSESSTNAGGYPFFDTAPAVAPAPAFHHHPAYGQPQGYGHKVYPTVDTLPSYQYNNFYPEHSHPTVGSVLTQQPTAGIHHPSAGGHSALSLINNIFSIYKPNKYSPENCQMNYESKPEPCKKMNVPSTHRPLGAAAHPYPAHDYMHSSMKRPLLVSADQPHFKIIPEKTGLKISPLLSYEDYGGGGGGEKAHHRLTSTARPLMLPH