wanglab/gogpt-training-data huggingface dataset:
Protein: Hyperkinetic, isoform I (M9NGY7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MCRAPIASLDCMEEFSGTGGHLDFGRSISLGSNPALPLRHGSTPTPGLRYKNLGKSGLRISNVGLGTWPVFSPGVSDDQAEAILKLAIESGINLFDISEAHSETEIGKILQRAGWKRTAYVITTKVYWSTKSEERGLSRKHIIECVRASLQRLQLQYIDIVIIHKADPMCPMEEVVRAMSYVIQQGWAMYWGTARWSQVEIMEAYTNCRQFNCITPIVEQSEYHMFCREKCELYLPEMYNKIGVGLMAWGPLSMALSDTQNGDKLFLPKGSFKTKSFSWTEDEINRNAALSPQGSWGKDRIDEGRRHCDRLRDLAALAEKLGCSPTQLSIAWSLKHEPVQCLLLGATSAEQLHQSLQSLQLLPRLSSSVMLELERILENKPVRPPMISTLALR
Protein: NAD(P)H-quinone oxidoreductase subunit K, chloroplastic (EC 7.1.1.-) (NAD(P)H dehydrogenase subunit K) (NADH-plastoquinone oxidoreductase subunit K) (P56756)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_01356}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01356}; Stromal side {ECO:0000255|HAMAP-Rule:MF_01356}.
Interaction partners:
- NAD
- NAD
- NAD
- NAD
- NAD
- NAD
- Photosystem I iron-sulfur center
- NAD
- NAD
- NAD
Sequence:
MNSIKFPILDRTTKNSVISTTLNDLSNWSRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLILTAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAVIDAITKLRKKIAREIYKDRIRPQQGNRCFTTNHKFFVVRSPHIGNYDQELLYPPSSTSEISTETFFKYKSPVSSHELVN
Protein: Inhibin beta C chain (Activin beta-C chain) (P55103)
Organism: Homo sapiens (Human)
Function: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
Subcellular location: Secreted {ECO:0000250}.
Interaction partners:
- Follistatin
- Activin receptor type-2B
- Activin receptor type-2A
- Activin receptor type-1C
- Transforming growth factor beta-3 proprotein
- Nodal homolog
- Transforming growth factor beta-1 proprotein
- Inhibin alpha chain
Sequence:
MTSSLLLAFLLLAPTTVATPRAGGQCPACGGPTLELESQRELLLDLAKRSILDKLHLTQRPTLNRPVSRAALRTALQHLHGVPQGALLEDNREQECEIISFAETGLSTINQTRLDFHFSSDRTAGDREVQQASLMFFVQLPSNTTWTLKVRVLVLGPHNTNLTLATQYLLEVDASGWHQLPLGPEAQAACSQGHLTLELVLEGQVAQSSVILGGAAHRPFVAARVRVGGKHQIHRRGIDCQGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS
Protein: Calponin-homology (CH) domain-containing protein (Q383H8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Trans sialidase, putative
Sequence:
MTLEHNDEFATEGAMHSVDDPATTSSNGNTHRKPVELSSNAVHGKASGADVLDGNASASTDGRTKPLNSGPTREAVDDVMMDECRRWVADVVGDAYNAEVLQKENFVDSLRSGVVLLVLLQKLDDPPVPDSELRVPKRVDGFFARDNVAKFLRQAAKKFNLTEIELFTDSDLCDGKNDRAVITCLLSIARTAYSRGNMEVAPASIVQQQELSVRIKQAALNQLRKHLAEEGEEDGKGEISKKLEPVAQEEVSHTPCENIPESGEPMKEIKNEVDVEAVVNESLADTEDYRSVEESEEADLPDVPQHGEQMRVGEVADDDKSRPSGTYETTTRHAPVRVRIEGRASDTIKLPQHRTIRATKESQGVAITPVPHQVEQEVNAPQPRGMETQRHGPTAPPAYRPRRWDKVDILLSVVVNAHFTQHPDTNIRFRRLSGNTGEYMVFHKVTGGKKLLHARTELGKVVVGEQRKKGNIEDLVWTDLSHWLERHERDFSN
Protein: LEM domain-containing protein 1 (Cancer/testis antigen 50) (CT50) (LEM domain protein 1) (LEMP-1) (Q68G75)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Barrier-to-autointegration factor
Sequence:
MVDVKCLSDCKLQNQLEKLGFSPGPILPSTRKLYEKKLVQLLVSPPCAPPVMNGPRELDGAQDSDDSEELNIILQGNIILSTEKSKKLKKWPEASTTKRKAVDTYCLDYKPSKGRRWAARAPSTRITYGTITKERDYCAEDQTIESWREEGFPVGLKLAVLGIFIIVVFVYLTVENKSLFG
Protein: Nitrogen regulatory protein GlnK (Nitrogen regulatory protein P-II 2) (PII-like protein) (P0AC55)
Organism: Escherichia coli (strain K12)
Function: Involved in the regulation of nitrogen metabolism. Regulates the activity of its targets by protein-protein interaction in response to the nitrogen status of the cell. Involved in the regulation of the ammonium transporter AmtB so as to optimize ammonium uptake under all growth conditions. In nitrogen-limited conditions, GlnK does not interact with AmtB, which remains active and imports ammonium. When extracellular ammonium increases, GlnK associates tightly with AmtB in the inner membrane, thereby inhibiting the transporter activity. Also involved in the regulation of the glutamine synthetase adenylyltransferase/adenylyl-removing (AT/AR) enzyme GlnE and the glutamine synthetase GlnA. In nitrogen-limited conditions, formation of uridylylated GlnB(PII)/GlnK heterotrimers may fine-regulate the activation of GlnA: uridylylated heterotrimers stimulate the deadenylation and the activation of GlnA whereas uridylylated GlnK homotrimers do not stimulate, or hardly stimulate, the deadenylation of GlnA. In addition, regulates the expression of Ntr genes during nitrogen starvation, probably via the control of the levels of phosphorylated NRI during different stages of the response to nitrogen limitation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:11847102, ECO:0000269|PubMed:14668330, ECO:0000269|PubMed:16864585}. Cell inner membrane {ECO:0000269|PubMed:11847102, ECO:0000269|PubMed:14668330, ECO:0000269|PubMed:16864585}. Note=During nitrogen limitation, GlnK is predominantly in its fully uridylylated state in the cytoplasmic fraction. In response to nitrogen shock, GlnK is deuridylylated rapidly and associates tightly with AmtB in the inner membrane. {ECO:0000269|PubMed:11847102, ECO:0000269|PubMed:14668330, ECO:0000269|PubMed:16864585}.
Interaction partners:
- Ammonium transporter AmtB
- Sensory histidine kinase/phosphatase NtrB)
- Bifunctional uridylyltransferase/uridylyl-removing enzyme
- Nitrogen assimilation regulatory protein nac
- DNA-binding transcriptional regulator NtrC)
- Nitrogen regulatory protein P-II 1
- Glutamine synthetase
- Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme
- Glutamate synthase large chain
Sequence:
MKLVTVIIKPFKLEDVREALSSIGIQGLTVTEVKGFGRQKGHAELYRGAEYSVNFLPKVKIDVAIADDQLDEVIDIVSKAAYTGKIGDGKIFVAELQRVIRIRTGEADEAAL
Protein: Kunitz trypsin inhibitor 4 (AtKTI4) (Kunitz trypsin inhibitor 1) (AtKTI1) (Trypsin protease inhibitor) (Q8RXD5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Exhibits Kunitz trypsin protease inhibitor activity. Involved in modulating programmed cell death (PCD) in plant-pathogen interactions. Can inhibit both serine proteases and cysteine proteases. May be involved in the modulation of the proteases that participate in the hydrolysis of dietary proteins in the gut of spider mites.
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:30042779}.
Interaction partners:
- Kunitz trypsin inhibitor 6
- At2g15220/F15A23.4
- Heavy metal-associated isoprenylated plant protein 43
- Kunitz trypsin inhibitor 7
- Heavy metal-associated isoprenylated plant protein 33
- Defensin-like protein 195
Sequence:
MTKTTKTMNPKFYLVLALTAVLASNAYGAVVDIDGNAMFHESYYVLPVIRGRGGGLTLAGRGGQPCPYDIVQESSEVDEGIPVKFSNWRLKVAFVPESQNLNIETDVGATICIQSTYWRVGEFDHERKQYFVVAGPKPEGFGQDSLKSFFKIEKSGEDAYKFVFCPRTCDSGNPKCSDVGIFIDELGVRRLALSDKPFLVMFKKANVTEVSSKTM
Protein: Lgt1 (Q5DIA2)
Organism: Moraxella catarrhalis (Branhamella catarrhalis)
Interaction partners:
Sequence:
MKILHVLLTRMPIPPTKYGGTERVLWALYQGQTALGHQVRFLLKANANHAPYVQVFDKSKPLHEQIDDWADMVHFHFPYEGELHKPFVCTEHSNSEVEKEFPINTIYLSSKHAENNHATCYVHNGLYWPDYGEPNFKPKDYCHFLAKASWRIKNLQGAVRIAKKANKPLHILGGNRFNIRRNPYCYLSSRLHFHGMVGGVKKNELIANSQALIFPVLWHEPFGLAVIESLYLGCPVFATPFGAMSDIVTQEVGLLSDSYAVLSEALKDVAQFDRLACHEHAKRHFSHLSMSNAYLDCYEKVLAGETLNAVKPKAKPDIKARQMMQDG
Protein: Stathmin-3 (Hippocampus abundant transcript 3) (SCG10-like protein) (SCG10-related protein HiAT3) (O70166)
Organism: Mus musculus (Mouse)
Function: Exhibits microtubule-destabilizing activity, which is antagonized by STAT3.
Subcellular location: Golgi apparatus. Cell projection, growth cone. Cell projection, axon. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9JHU6}.
Interaction partners:
Sequence:
MASTVSAYKEKMKELSVLSLICSCFYSQPHPNTIYQYGDMEVKQLDKRASGQSFEVILKSPSDLSPESPVLSSPPKRKDASLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRLAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEMSG
Protein: Uncharacterized protein At2g36145 (Q67XT7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
SRKMAFAATLFVPPPVAVRSPARFLGRLSIPCLLQVLPTNGAASPRQVKRAIVANASPGNGGVKAEEEDGVSLGTMKLPVDTDLARFETLLFQWANSLCQGANLPLPVPLKVDRISGGARLGFIVMEDEGKTDVPVYIDCLVFQTTENGVVFQATRNGRKKDKAPPGEERIMRSLLGALKKAVEIARVT
Protein: Clathrin light chain 1 (Q9SKU1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Membrane, coated pit {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Cytoplasmic face of coated pits and vesicles. {ECO:0000250}.
Interaction partners:
- Clathrin heavy chain 1
- AP-1 complex subunit sigma-2
- AP-2 complex subunit mu
- Phragmoplastin DRP1C
- AP-1 complex subunit mu-2
- At5g57460
- Probable protein phosphatase 2C 73
- AP-2 complex subunit sigma
- Protein TPLATE
- AP-1 complex subunit sigma-1
Sequence:
MATFDDGDFPAQTHSPSEHEDFGGYDNFSEAQQPPTQHQSGGFSSFNGDPASPNGYGFGASSPNHDFSSPFESSVNDANGNGGGSGGDAIFASDGPILPDPNEMREEGFQRREWRRLNTIHLEEKEKKEKEMRNQIITEAEDFKKAFYEKRDKTIETNKTDNREKEKLYWANQEKFHKEVDKHYWKAIAELIPREVPNIEKKRGKKDPDKKPSVNVIQGPKPGKPTDLGRMRQIFLKLKTNPPPHMMPPPPPAKDAKDGKDAKDGKDAKTGKDGKDAKGGKDAKDLKDGKPADPKVTEEKRPSPAKDASVETAKPDAAASGEGEKPVAVTEAEGTKAE
Protein: DEAD-box ATP-dependent RNA helicase 15 (EC 3.6.4.13) (UAP56 homolog A) (Q56XG6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: ATP-dependent RNA helicase involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus. In addition to ssRNA and dsRNA, binds dsDNA, but not ssDNA.
Subcellular location: Nucleus {ECO:0000269|PubMed:22499202, ECO:0000269|PubMed:23555998}. Note=Localizes predominantly to euchromatic regions of the nucleoplasm.
Interaction partners:
- THO complex subunit 4B
- THO complex subunit 4A
- Protein MODIFIER OF SNC1 11
- THO complex subunit 4C
- THO complex subunit 4D
- THO complex subunit 2
- RNA-binding protein Y14
- THO complex subunit 3
- THO complex subunit 6
- ATP-dependent RNA helicase DEAH12, chloroplastic
Sequence:
MGDARDNEAYEEELLDYEEEDEKVPDSGNKVNGEAVKKGYVGIHSSGFRDFLLKPELLRAIVDSGFEHPSEVQHECIPQAILGMDVICQAKSGMGKTAVFVLSTLQQIEPSPGQVSALVLCHTRELAYQICNEFVRFSTYLPDTKVSVFYGGVNIKIHKDLLKNECPHIVVGTPGRVLALAREKDLSLKNVRHFILDECDKMLESLDMRRDVQEIFKMTPHDKQVMMFSATLSKEIRPVCKKFMQDPMEIYVDDEAKLTLHGLVQHYIKLSEMEKNRKLNDLLDALDFNQVVIFVKSVSRAAELNKLLVECNFPSICIHSGMSQEERLTRYKSFKEGHKRILVATDLVGRGIDIERVNIVINYDMPDSADTYLHRVGRAGRFGTKGLAITFVASASDSEVLNQVQERFEVDIKELPEQIDTSTYMPS
Protein: LD31195p (Sprouty-related protein with EVH-1 domain, isoform B) (F0JAK5)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MTEGHESDFLVTVRAQVMTRDESTEGWLPLAGGGLANVSIRKRARLSPLASGHDYIIYGQRISDQSVILSCVINRDLKYYKVMPTFHHWRAGKQRNGLTFQTAADARAFDKGVLRAYNELIDDDVFMTLDLPVESESLQKIHSSPEGSEKSHKSVSNNSDSEKLPPPPIHYISTDKTSATTSPPDAPPASAAPSPATAGQIAASENYSYVTLTAVHHDYNYPVVDQPVGAQVLNARRESISALKKRNALEAAQAMAAAQTAAGGGLACRDGGSGKPLHKPNVSDILKKETRLRCRYCHELYSEDFNRRGACEYAPDAFRSGYECISGMGCARCMIYHCMSDAEGETAQHPCDCSASEAGCSKRWLGLAILSLFVPCLWCYPPLRACHLAGIHCGLCGGQHKPHV
Protein: Sucrose transport protein SUC2 (AtSUC2) (Sucrose permease 2) (Sucrose transporter 1) (Sucrose-proton symporter 2) (Q39231)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Responsible for the transport of sucrose into the cell, with the concomitant uptake of protons (symport system). Can also transport other glucosides such as maltose, arbutin (hydroquinone-beta-D-glucoside), salicin (2-(hydroxymethyl)phenyl-beta-D-glucoside), alpha-phenylglucoside, beta-phenylglucoside, alpha-paranitrophenylglucoside, beta-paranitrophenylglucoside, and paranitrophenyl-beta-thioglucoside. May also transport biotin. Required for apoplastic phloem sucrose loading in source tissues (e.g. leaves) in order to transport it to sink tissues (e.g. roots, flowers).
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Bidirectional sugar transporter SWEET11
- Bidirectional sugar transporter SWEET12
- Sucrose synthase 3
- Sucrose synthase 2
- Sucrose synthase 1
- Sucrose synthase 4
- Bidirectional sugar transporter SWEET1
- Sucrose synthase 5
- Sucrose synthase 6
- Wall-associated receptor kinase-like 8
Sequence:
MVSHPMEKAANGASALETQTGELDQPERLRKIISVSSIAAGVQFGWALQLSLLTPYVQLLGIPHKWASLIWLCGPISGMLVQPIVGYHSDRCTSRFGRRRPFIVAGAGLVTVAVFLIGYAADIGHSMGDQLDKPPKTRAIAIFALGFWILDVANNTLQGPCRAFLADLSAGNAKKTRTANAFFSFFMAVGNVLGYAAGSYRNLYKVVPFTMTESCDLYCANLKTCFFLSITLLLIVTFVSLCYVKEKPWTPEPTADGKASNVPFFGEIFGAFKELKRPMWMLLIVTALNWIAWFPFLLFDTDWMGREVYGGNSDATATAASKKLYNDGVRAGALGLMLNAIVLGFMSLGVEWIGRKLGGAKRLWGIVNFILAICLAMTVVVTKQAENHRRDHGGAKTGPPGNVTAGALTLFAILGIPQAITFSIPFALASIFSTNSGAGQGLSLGVLNLAIVVPQMVISVGGGPFDELFGGGNIPAFVLGAIAAAVSGVLALTVLPSPPPDAPAFKATMGFH
Protein: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (Complex I-B14.5a) (CI-B14.5a) (NADH-ubiquinone oxidoreductase subunit B14.5a) (Q9Z1P6)
Organism: Mus musculus (Mouse)
Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:38575788}; Peripheral membrane protein {ECO:0000269|PubMed:38575788}; Matrix side {ECO:0000269|PubMed:38575788}.
Interaction partners:
- NADH dehydrogenase 1 alpha subcomplex subunit 5
- NADH dehydrogenase 1 alpha subcomplex subunit 3
- NADH dehydrogenase iron-sulfur protein 7, mitochondrial
- NADH dehydrogenase iron-sulfur protein 5
- NADH dehydrogenase 1 alpha subcomplex subunit 1
- NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 13
- NADH dehydrogenase iron-sulfur protein 8, mitochondrial
Sequence:
MASATRVIQKLRNWASGQDLQAKLQLRYQEIAKRTQPPPKLPVGPSHKLSNNYYCTRDGRREVVPPSIIMSSQKALVSGKAAESSAMAATEKKAVTPAPPMKRWELSKDQPYL
Protein: Protein kinase activator Bem1, putative (AFU_orthologue AFUA_4G04120) (Q5AXF0)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- Guanine nucleotide exchange factor Cdc24, putative
- CD42_CHICK Cell division control protein 42 homolog
- Serine/threonine-protein kinase ste20
- non-specific serine/threonine protein kinase
- RacA
- Uncharacterized protein
- NADPH oxidase complex regulatory component
- Rho GTPase activator Rga
- Exocyst complex component SEC15
- von Willebrand and RING finger domain protein
Sequence:
MKALRRSLKGEKDSKPHHHHQHHHQQHHHLSITPKSAVAILPPKKVIKALYDYQPEPGNTQELAFSKGDFFHVISREDDSDWYEACNPLIPTARGLVPVTFFEVIGKTQRDSSGSIDLGKKKEPHDSGFADRATSSGSEFGSGSSKSYQSHPAFPRTSMMGKAGGGAMVYGVVQYDFQAERPDELDAKAGEAIIVIAQSNPEWFVAKPIGRLGGPGLIPVSFIELRDMQSGQAVADPLEAVRRAGVPKVEEWKKMTAEYKNSSISLGKIETTGSMQSVTSGMERMSVRQSADHVSHMSQNGHANAYHNRNASKASIAPSTHQQPPPHSQQPLVAPIAASIPRYCFDNDKYWYIIEVKMEDGRCWELSRYYHDFYDFQIALLTQFEEEAGNRGKPRTLPFMPGPVAHVTDAISDGRRHNLDEYIKKLLAMPPHITRCALVRQLFAPRPGDFEIDPSAFGEDARFSGGSQHSSGHELSPSASRQSSQQQNGPSERSSHSHSHSHSHSHQRSQTSSSIPNGKPPMVRQQSSLTQVSTSSGGALKVKVNFQDDLIAIRVPSDINVQQLKEKLMDRLKINDEIVVQYKDEASGAYVDLISDSDLDTAIQRNSKLTLYVGLA
Protein: Inactive caspase-12 (CASP-12) (Q6UXS9)
Organism: Homo sapiens (Human)
Function: Has no protease activity. May reduce cytokine release in response to bacterial lipopolysaccharide during infections. Reduces activation of NF-kappa-B in response to TNF.
Interaction partners:
Sequence:
MADEKPSNGVLVHMVKLLIKTFLDGIFDDLMENNVLNTDEIHLIGKCLKFVVSNAENLVDDITETAQIAGKIFREHLWNSKKQLSSDISSDGEREANMPGLNIRNKEFNYLHNRNGSELDLLGMRDLLENLGYSVVIKENLTAQEMETALRQFAAHPEHQSSDSTFLVFMSHSILNGICGTKHWDQEPDVLHDDTIFEIFNNRNCQSLKDKPKVIIMQACRGNGAGIVWFTTDSGKASADTHGRLLQGNICNDAVTKAHVEKDFIAFKSSTPHNVSWRHETNGSVFISQIIYYFREYSWSHHLEEIFQKVQHSFETPNILTQLPTIERLSMTRYFYLFPGN
Protein: Sulfate transport system permease protein CysT (P71745)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Sulfate/thiosulfate import ATP-binding protein CysA
- Probable sulfate-binding lipoprotein SubI
- Bifunctional enzyme CysN/CysC
- Probable sulfate-transport integral membrane protein ABC transporter CysW
- Sulfate adenylyltransferase subunit 2
- Molybdate-binding protein ModA
- Molybdenum import ATP-binding protein ModC
- Phosphoserine phosphatase SerB1
- Adenosine 5'-phosphosulfate reductase
Sequence:
MTESLVGERRAPQFRARLSGPAGPPSVRVGMAVVWLSVIVLLPLAAIVWQAAGGGWRAFWLAVSSHAAMESFRVTLTISTAVTVINLVFGLLIAWVLVRDDFAGKRIVDAIIDLPFALPTIVASLVMLALYGNNSPVGLHFQHTATGVGVALAFVTLPFVVRAVQPVLLEIDRETEEAAASLGANGAKIFTSVVLPSLTPALLSGAGLAFSRAIGEFGSVVLIGGAVPGKTEVSSQWIRTLIENDDRTGAAAISVVLLSISFIVLLILRVVGARAAKREEMAA
Protein: Cysteine--tRNA ligase 2, cytoplasmic (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS) (B3LFA4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Cytoplasm, cytosol {ECO:0000305|PubMed:16251277, ECO:0000305|PubMed:16297076}.
Interaction partners:
- Leucine--tRNA ligase, cytoplasmic
- Valine--tRNA ligase, chloroplastic/mitochondrial 2
- Valine--tRNA ligase, mitochondrial 1
- Methionine--tRNA ligase, cytoplasmic
- Leucine--tRNA ligase, chloroplastic/mitochondrial
- Histidine--tRNA ligase, cytoplasmic
- Probable elongation factor 1-gamma 2
- Probable threonine--tRNA ligase, cytoplasmic
- Threonine--tRNA ligase, chloroplastic/mitochondrial 2
- Putative glycine--tRNA ligase, cytoplasmic
Sequence:
MEAEKMELKLYNTMTQQKEVLIPITPGKIGLYVCGITAYDFSHIGHARAAVSFDVLYRYLKHLDYDVTFVRNFTDVDDKIIDRANKNGEDPLDLSNRFCDEYLVDMGALQCLPPTHQPRVSEHMDNIIKMIEKIIEKDCGYVVEGDVFFSVDKSPNYGKLSGQLLEHTRAGERVAVDSRKRNPADFALWKAAKPDEPSWESPWGPGRPGWHIECSAMSVHYLSPKFDIHGGGADLKFPHHENEIAQTCAACEDSGVNYWLHNGHVTINNEKMAKSKHNFKTIREITASYHPLALRHFLMSAQYRSPLSFTASQLESSSEALYYVYQTLQDLDEGLSPYQDALSEDGGKSEQTAEGKDIIKKLKTEFESKMLDDLNTAHILTGAYQDALKFINASLSKLKKMQKKQRMSMLVSLVEIEKAAREVLDVLGLLTTLSYAEILKEMKLKTLIRAEIGEEGISQLIEERITARKNKDFAKSDEIREKLTRKGIALMDIGKETVWRPCFPSQADSST
Protein: DNA-directed RNA polymerase subunit omega (RNAP omega subunit) (EC 2.7.7.6) (RNA polymerase omega subunit) (Transcriptase subunit omega) (P9WGY5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
Interaction partners:
- DNA-directed RNA polymerase subunit alpha
- DNA-directed RNA polymerase subunit beta'
- RNA polymerase sigma factor SigA
- DNA-directed RNA polymerase subunit beta
- RNA polymerase-binding protein RbpA
- Guanylate kinase
- Probable helicase HelZ
- RNA polymerase sigma factor SigB
- Transcription termination/antitermination protein NusA
- Integration host factor
Sequence:
MSISQSDASLAAVPAVDQFDPSSGASGGYDTPLGITNPPIDELLDRVSSKYALVIYAAKRARQINDYYNQLGEGILEYVGPLVEPGLQEKPLSIALREIHADLLEHTEGE
Protein: Cytosol aminopeptidase (EC 3.4.13.23) (Cysteinylglycine-S-conjugate dipeptidase) (Leucine aminopeptidase 3) (Proline aminopeptidase) (Prolyl aminopeptidase) (Q500X4)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- GH06096p
- Male-specific sperm protein Mst84Dc
- Cytosol aminopeptidase
- FI13205p
- GEO13348p1
- AT21693p
- GH09231p
- GEO12122p1
- 10 kDa heat shock protein, mitochondrial
- Cytosol aminopeptidase
Sequence:
MNKLRQIHCSLKNACVLCKPHVLSSAGVRFSCGDGKTMAKGVVVGLYQKEGDKDPKLTPAGHKIDQRVQGKLMKAICETKLDGRLGRGKVFHNIDTEFAAVAVVGVGLEGIGFNELEMLDEGMEFVRVAAGVGARSLQQQGITNVLVDGMDYAEQAAEGSQLAVWRFPDNLSKKNMPMVPTLELFESPDHEGWTRGIFKAEAQNLARRLSDAPANCMTPTMFAQAAVDALCPCGITVEVRTMDWIEAQRLNAFLMIAKGSCEPPVLLELSYCGTAPDDKPILFVGKGITFNSGALNLRPCRGMDEYRGSMSAAACCVAMMRCIAALSLPINVTCIIPLCENMPSGMSAKPGDVVTLLNGKSMAIRDLDKAGVVVLSDPLLYGQKTYLPRLVVDIATLNTGVKKAFGGGATGIWSNSHYIWKQFQRAGSISGDRVWRLPLWQYYRRQVTDERAYDLSNNGRGLASSCLAAAILHELVPCVDWAHLDTRGTGLLSKYGLVPYLTKKRMTGRPTRTLVQFVYQMACPEMK
Protein: KIF-binding protein (KIF1-binding protein) (Q6ZPU9)
Organism: Mus musculus (Mouse)
Function: Required for neuronal development and differentiation. Required for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central nervous system development.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q96EK5}.
Interaction partners:
- U6 snRNA-associated Sm-like protein LSm1
- CCR4-NOT transcription complex subunit 1
- U6 snRNA-associated Sm-like protein LSm7
- CCR4-NOT transcription complex subunit 4
- Protein LSM14 homolog A
- Protein LSM14 homolog B
- CCR4-NOT transcription complex subunit 3
- m7GpppN-mRNA hydrolase
- Kinesin-like protein KIF1B
- Protein PAT1 homolog 2
Sequence:
MANAPGPEIREKFQAALALSRVELHKNPEKEPYKSKYGARALLEEVRALLGPAPEDEDEPAADDGPGDQALGAGEPREAEGPGAQRALRLAVVEFHLGVNHIDTEELSAGEEHLVRCLSLLRPYRLSLGCVSLYIQAQNNLGILWSEREEIETARTYLESSEALYSQYMKEIGSPPLDPTEHFLPEEEKLTEQERSKRFEKVYTHNLYYLAQVYQHMEMFEKAAHYCHSTLKRQLEHNAYHPMEWAINAATLSQFYINKLCFMEARHCLSAANVIFGQTGKIPATEDTPEVEGDVPELYHQRKGEIARCWIKYCLTLMQNAQLSMQDNIGELDLDKQSELRALRKKELDEEESVRKRAVQFGTGELCDAISAVEEKVRYLRPLDFEEARELFLLGQHYVCEAKEFFQIDGYVTDHIEVVQDHSALFKVLSFFEADMERRCKMHKRRIAMLEPLTVDLNPQYYLLVSRQIQFEIAHAYYDMMDLKVAIADKLRDPDSHIVKKINSLNKSALKYYQLFLDSLRDPNKVFPEHIGEDVLRPAMLAKFRVARLYGKIITADPKKELENLATSLEHYKFIVDYCETHPEAAQEIEVELELSKEMVSLLPTKMERFRAKMALT
Protein: Uncharacterized protein (Q38F16)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSCDQLTCADKRNFVVIMSIERLRREVEQQERRVAALREKKVRRYAVLSQVRLLMNTTDPTSFTALSNSLWQLLHDMAAAETLAVNGDDPTITESVSRSASDGLFSKEMEQRIMQEEEPPLKGEWSYEDEDESVDQKKRKKRRRRQKQRKERLGGVEATGRTLALAEDNARSALLAAVDALQLDGAPQQVVGVPEWLADVETTEPGELYSGGKSDGSDKEEENVYSDDFDELSDD
Protein: BTB and MATH domain-containing protein 42 (P34371)
Organism: Caenorhabditis elegans
Function: Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Interaction partners:
- Inositol polyphosphate 5-phosphatase
- Cullin-3
- BTB domain-containing protein
- BTB domain-containing protein
- BTB domain-containing protein
- UBR-type domain-containing protein
- REPS homolog
- FLYWCH transcription factor 1
- Serine/threonine-protein kinase sel-5
Sequence:
MSSRSSWSSTEQINRTISSRADDLPPQPRRLEVVSKQATRVTALSTKLEWKIEQFEKLMKLIKNGSNLISRMFSVPDAPTVCWELHVYPNGKRDEDVNNVSFFLRQVGLARGEEPIMTEFQIYALDANNQRVSVCRDTKDFTNQQGRGKFQVSRDKMLGALRSDGTLFLICEVEYFPPGSKISVEPVVDEDVSTEEQEEMPEVIVRANNRSMWEDELFTDCVIHVGNKHIKAHRCILGQNSPVFKSMFSSPNMIEAQKGEIHIEDAKYDSVRAMVEFMYTGATESLESQGNIDEILAIADKYEVLMLKDQCERLIAQTINLKNVTQIAMFSDTYTADYLKSAVIRFLTTHHRVVIKTQDWISLKKSRHELANELLEAVLSTDQDDDDVTSNIPISVSPPPARKRLRRSAK