wanglab/gogpt-training-data huggingface dataset:
Protein: Ethylene-responsive transcription factor ERF071 (AtERF71) (Protein HYPOXIA RESPONSIVE ERF 2) (O22259)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional activator that binds specifically to the cis-acting element GCC box 5'-AGCCGCC-3', or to the CRT/DRE element 5'-[AG]CCGAC-3'. Plays an important role in root development via root cell expansion regulation. Transcriptional activator involved in the hypoxic stress response. Plays a role in low oxygen signaling and contributes to tolerance to anoxia stress by enhancing anaerobic gene expression and ethanolic fermentation. Plays a role in the regulation of hypoxia-induced root slanting. Contributes to the promotion of adventitious root elongation under hypoxia, an adaptation response that strengthens the root system in upper soil layers where oxygen shortage may last for shorter time periods. Transcriptional activator involved in the osmotic stress response. May play a role in defense response against the fungal pathogen Fusarium graminearum downstream of ethylene signaling.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00366, ECO:0000269|PubMed:20113439, ECO:0000269|PubMed:21946064}.
Interaction partners:
- Anaerobic nitrite reductase AHB1
Sequence:
MCGGAIISDFIWSKSESEPSQLGSVSSRKKRKPVSVSEERDGKRERKNLYRGIRQRPWGKWAAEIRDPSKGVRVWLGTFKTADEAARAYDVAAIKIRGRKAKLNFPNTQVEEEADTKPGGNQNELISENQVESLSEDLMALEDYMRFYQIPVADDQSATDIGNLWSYQDSN
Protein: Plexin-A3 (Plexin-4) (Semaphorin receptor SEX) (P51805)
Organism: Homo sapiens (Human)
Function: Coreceptor for SEMA3A and SEMA3F. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Regulates the migration of sympathetic neurons, but not of neural crest precursors. Required for normal dendrite spine morphology in pyramidal neurons. May play a role in regulating semaphorin-mediated programmed cell death in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
- Semaphorin-3F
- Neuropilin-1
- Semaphorin-3A
- Neuropilin-2
- Semaphorin-3B
- Semaphorin-6A
- Rho-related GTP-binding protein Rho6
- Ras-related C3 botulinum toxin substrate 2
- Tyrosine-protein kinase Fes/Fps
- Ras-related C3 botulinum toxin substrate 3
Sequence:
MPSVCLLLLLFLAVGGALGNRPFRAFVVTDTTLTHLAVHRVTGEVFVGAVNRVFKLAPNLTELRAHVTGPVEDNARCYPPPSMRVCAHRLAPVDNINKLLLIDYAARRLVACGSIWQGICQFLRLDDLFKLGEPHHRKEHYLSGAQEPDSMAGVIVEQGQGPSKLFVGTAVDGKSEYFPTLSSRKLISDEDSADMFSLVYQDEFVSSQIKIPSDTLSLYPAFDIYYIYGFVSASFVYFLTLQLDTQQTLLDTAGEKFFTSKIVRMCAGDSEFYSYVEFPIGCSWRGVEYRLVQSAHLAKPGLLLAQALGVPADEDVLFTIFSQGQKNRASPPRQTILCLFTLSNINAHIRRRIQSCYRGEGTLALPWLLNKELPCINTPMQINGNFCGLVLNQPLGGLHVIEGLPLLADSTDGMASVAAYTYRQHSVVFIGTRSGSLKKVRVDGFQDAHLYETVPVVDGSPILRDLLFSPDHRHIYLLSEKQVSQLPVETCEQYQSCAACLGSGDPHCGWCVLRHRCCREGACLGASAPHGFAEELSKCVQVRVRPNNVSVTSPGVQLTVTLHNVPDLSAGVSCAFEAAAENEAVLLPSGELLCPSPSLQELRALTRGHGATRTVRLQLLSKETGVRFAGADFVFYNCSVLQSCMSCVGSPYPCHWCKYRHTCTSRPHECSFQEGRVHSPEGCPEILPSGDLLIPVGVMQPLTLRAKNLPQPQSGQKNYECVVRVQGRQQRVPAVRFNSSSVQCQNASYSYEGDEHGDTELDFSVVWDGDFPIDKPPSFRALLYKCWAQRPSCGLCLKADPRFNCGWCISEHRCQLRTHCPAPKTNWMHLSQKGTRCSHPRITQIHPLVGPKEGGTRVTIVGENLGLLSREVGLRVAGVRCNSIPAEYISAERIVCEMEESLVPSPPPGPVELCVGDCSADFRTQSEQVYSFVTPTFDQVSPSRGPASGGTRLTISGSSLDAGSRVTVTVRDSECQFVRRDAKAIVCISPLSTLGPSQAPITLAIDRANISSPGLIYTYTQDPTVTRLEPTWSIINGSTAITVSGTHLLTVQEPRVRAKYRGIETTNTCQVINDTAMLCKAPGIFLGRPQPRAQGEHPDEFGFLLDHVQTARSLNRSSFTYYPDPSFEPLGPSGVLDVKPGSHVVLKGKNLIPAAAGSSRLNYTVLIGGQPCSLTVSDTQLLCDSPSQTGRQPVMVLVGGLEFWLGTLHISAERALTLPAMMGLAAGGGLLLLAITAVLVAYKRKTQDADRTLKRLQLQMDNLESRVALECKEAFAELQTDINELTNHMDEVQIPFLDYRTYAVRVLFPGIEAHPVLKELDTPPNVEKALRLFGQLLHSRAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYATGLLKQLLADLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLHCVCPENEGSAQVPVKVLNCDSITQAKDKLLDTVYKGIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLNSLAHYQVTDGSLVALVPKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSLRSRAPMITPDQETGTKLWHLVKNHDHADHREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETVFSTAHRGSALPLAIKYMFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVERYYRDIAKMASISDQDMDAYLVEQSRLHASDFSVLSALNELYFYVTKYRQEILTALDRDASCRKHKLRQKLEQIISLVSSDS
Protein: Hephaestin (EC 1.16.3.1) (Q920H8)
Organism: Rattus norvegicus (Rat)
Function: May function as a ferroxidase for ferrous (II) to ferric ion (III) conversion and may be involved in copper transport and homeostasis. Implicated in iron homeostasis and may mediate iron efflux associated to ferroportin 1 (By similarity).
Subcellular location: Basolateral cell membrane {ECO:0000250|UniProtKB:Q9BQS7}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Ferroportin
- Heme oxygenase 1
- Ferrochelatase
- Heme oxygenase 2
- Ceruloplasmin
- Plasma membrane ascorbate-dependent reductase CYBRD1
- Natural resistance-associated macrophage protein 2
- Hepcidin
- Transferrin receptor protein 2
- Hemojuvelin
Sequence:
MKAGHLLWALLLMHSLCSLPTDGAIRNYYLGIQDIQWNYAPKGRNVITNQTLNNDTVASSFLKSGKNRIGGTYKKTVYKEYSDGTYTNEIAKPAWLGFLGPLLKAEMGDVILIHLKNFASRPYTIHPHGVFYEKDSEGSLYPDGSSGYLKADDSVPPGGSHVYNWSIPEGHAPTEADPACLTWIYHSHVDAPRDIATGLIGPLITCKRGTLDGNSPPQRKDVDHNFFLLFSVIDENLSWHLDDNIATYCSDPASVDKEDGPFQDSNRMHAINGFVFGNLPELSMCAQKHVAWHLFGMGNEIDVHTAFFHGQTLSIRGHRTDVAHIFPATFVTAEMVPQKSGTWLISCVVNSHLKSGMQAFYKVDSCSMDPPVEQLTGKVRQYFIQAHEIQWDYGPIGHDGRTGKSLREPGSGPDKYFQKSSSRIGGTYWKVRYEAFQDETFQERLHQEEETHLGILGPVIRAEVGDTIQVVFYNRASQPFSIQPHGVFYEKSSEGTVYNDGTSYPKVAKSFEKVTYYWTVPPHAGPTAEDPACLTWMYFSAADPTRDTNSGLVGPLLVCKAGALGEDGKQKGVDKEFFLLFTIFDENESWYNNANQAAGMLDSRLLSEDVEGFEDSNRMHAINGFLFSNLPRLDICKGDTVAWHLLGLGTENDVHGVMFEGNTLQLQGMRKSAAMLFPHTFVTAIMQPDNPGIFEIYCQAGSHREAGMQAIYNVSQCSSHQDSPRQHYQASRVYYIMAEEIEWDYCPDRSWELEWYNTSEKDSYGHVFLSNKDGLLGSKYKKAVFREYTDGTFRIPQPRSGPEEHLGILGPLIRGEVGDILTVVFKNKASRPYSIHAHGVLESSTGWPQAAEPGEVLTYQWNIPERSGPGPSDSACVSWIYYSAVDPIKDMYSGLVGPLVICRNGILEPNGGRNDMDREFALLFLIFDENQSWYLKENIATYGPQETSHVNLQDATFLESNKMHAINGKLYANLRGLTVYQGERVAWYMLAMGQDTDIHTVHFHAESFLYQNGHSYRADVVDLFPGTFEVVEMVASNPGAWLMHCHVTDHVHAGMETIFTVLSHEEHFSTMTTITKEIGKAVILQNIGEGNVKMLGMNIPVKNVEILSSALIAICVVLLLIALALGGVVWYQHRQRKLRRNRRSILDDSFKLLSLKQ
Protein: D(1A) dopamine receptor (Dopamine D1 receptor) (P18901)
Organism: Rattus norvegicus (Rat)
Function: Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11331877}; Multi-pass membrane protein {ECO:0000269|PubMed:11331877}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:11331877}; Multi-pass membrane protein {ECO:0000269|PubMed:11331877}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q61616}. Cell projection, cilium membrane {ECO:0000250|UniProtKB:P21728}; Multi-pass membrane protein {ECO:0000255}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:Q61616}. Note=Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14. {ECO:0000269|PubMed:11331877}.
Interaction partners:
- Guanine nucleotide-binding protein G
- Neuron-specific vesicular protein calcyon
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Pro-opiomelanocortin
- Neuroendocrine secretory protein 55
- Pituitary adenylate cyclase-activating polypeptide
- VIP peptides
- Pro-glucagon
- Natriuretic peptides A
Sequence:
MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDTEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST
Protein: Lysophospholipid acyltransferase LPCAT4 (1-acylglycerol-3-phosphate O-acyltransferase 7) (1-AGP acyltransferase 7) (1-AGPAT 7) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (1-alkenylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.121) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acyltransferase-like 3) (Lysophosphatidylcholine acyltransferase 4) (Lysophosphatidylethanolamine acyltransferase 2) (EC 2.3.1.n7) (Plasmalogen synthase) (Q6NVG1)
Organism: Mus musculus (Mouse)
Function: Displays acyl-CoA-dependent lysophospholipid acyltransferase activity with a subset of lysophospholipids as substrates; converts lysophosphatidylethanolamine to phosphatidylethanolamine, 1-alkenyl-lysophatidylethanolamine to 1-alkenyl-phosphatidylethanolamine, lysophosphatidylglycerol and alkyl-lysophosphatidylcholine to phosphatidylglycerol and alkyl-phosphatidylcholine, respectively. In contrast, has no lysophosphatidylinositol, glycerol-3-phosphate, diacylglycerol or lysophosphatidic acid acyltransferase activity. Prefers long chain acyl-CoAs (C16, C18) as acyl donors (By similarity). Converts lysophosphatidylcholine to phosphatidycholine.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q643R3}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Lysophospholipid acyltransferase 5
- Lysocardiolipin acyltransferase 1
- Membrane-bound glycerophospholipid O-acyltransferase 2
- Membrane-bound glycerophospholipid O-acyltransferase 1
- Acyl-CoA:lysophosphatidylglycerol acyltransferase 1
- Phosphatidylserine decarboxylase proenzyme, mitochondrial
- Lysophosphatidylcholine acyltransferase 1
- Cardiolipin synthase
- Lysophosphatidylcholine acyltransferase 2
- Lysophosphatidylcholine acyltransferase 2B
Sequence:
MSQGSPGAWAPLDPTSGSSASPNPFVHELHLSGLQRVKFCLLGVLLAPIRVLLAFIVLFLLWPFAWLQVAGLTEEQLQEPITGWRKTVCHNGVLGLSRLLFFLLGFLRIRVRGQRASRLEAPVLVAAPHSTFFDPIVLLPCDLPKVVSRAENLSVPVIGALLRFNQAILVSRHDPASRRRVVEEVRRRATSGGKWPQVLFFPEGTCSNKKALLKFKPGAFIAGVPVQPVLIRYPNSLDTTSWAWRGPGVLKVLWLTASQPCSIVDVEFLPVYQPSLEESKDPTLYANNVQRVMAQALGIPATECEFVGSLPVIVVGQLKVALEPQLWELAKVLQKAGLSPGFVDMGAEPGRSRMISQEAFAQQLQLSDPQTVAGAFSYFQQDAKGLVDFRNVALALAALDGGRSLEELTRLAFELFAEEQAEGSDRLLYKDGFSTILHLLLGSPRPAATTLHAELCQPGCSQGLSLCQFQNFSLHDPLYGKLFSAYLRPPHKPRSTSQIPNASSPSSPTALANGTVQAPKQKGD
Protein: Dynein light chain Tctex-type (TCTEX-1 protein homolog) (Q94524)
Organism: Drosophila melanogaster (Fruit fly)
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Required for spermatid differentiation. Is not required for polarized transport in rhabdomere development and appears to be a non-essential component of the cytoplasmic dynein complex.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000305}.
Interaction partners:
- Dynein light chain 1, cytoplasmic
- Cytoplasmic dynein 1 intermediate chain
- Dynein light intermediate chain
- Dynein light chain 2, cytoplasmic
- Dynein light chain roadblock
- Dynein heavy chain
- Sperm-specific dynein intermediate chain 2, isoform A
- GH16657p
- Sperm-specific dynein intermediate chain 1, isoform A
- FI21737p1
Sequence:
MDDSREESQFIVDDVSKTIKEAIETTIGGNAYQHDKVNNWTGQVVENCLTVLTKEQKPYKYIVTAMIMQKNGAGLHTASSCYWNNDTDGSCTVRWENKTMYCIVSVFGLAV
Protein: Transcription regulator, Crp family (Q5E833)
Organism: Aliivibrio fischeri (strain ATCC 700601 / ES114) (Vibrio fischeri)
Interaction partners:
Sequence:
MNDLFTTQLESHGFTPHEISQIVKLGKLKTLPAKSILIKQNNVANEFYFLIDGFCHSCYLTEQGKQFSKEFYWKGDWVVGFEELLDQTSSPYTLETITQTSLITLPISLLDRWRKNALPLYIKLLETQLLYKERKERFMLLHSPQARYEVFCQNYPELLAQLNDYQVAAYLGITHISLSRIKNRIKKLT
Protein: GH05406p (Mitochondrial ribosomal protein S30, isoform A) (Mitochondrial ribosomal protein S30, isoform B) (Q9VXP3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Interaction partners:
- Small ribosomal subunit protein mS29
- GH07821p
- Small ribosomal subunit protein uS9m
- Large ribosomal subunit protein mL66
- Mitochondrial ribosomal protein S23
- Small ribosomal subunit protein uS7m
- LD24471p
- Small ribosomal subunit protein uS15m
- FI07234p
- Mitochondrial ribosomal protein S21, isoform A
Sequence:
MLKLNRVRHLRTTYKRCLSGQSQLQLNSTDAEPAYPEIQDLSFKARKQKDAANWHEEIRQVPTVEEKMIKINMPRYYGFKVVDFNDSKIPYNALPLTQHYTRTVLEDLPSETDKKAQAKDSEQEQEQPSVDGLFKAARGDVIDALEFAHDYYKHLEKQHNSAESNPVERERILTQIIVEQLNRALLQSLSEEYKHLDELDVDYNPRHEAFWAVGGVDPPKNVQKSKKGREWQKDMANESVDRMVQYTGAPYLALRHRKQLTPWKTEAESENLELSKQLPRFKHDPRTLGYSTKHQHATNVPGYWPKGNENNFGLLSFQSRAHLQIRPKSFGEQDQLEALHSLAIKSSYAWLLAQANYNGFNTYNELTYPMNTQTVITNGREWSFYEYQLNTLLLHGTNVAENPRVNFCRGTKPLPLYAEISASGKCVDFNDNALRHLLNFYANAPSIQRSIGEQQPYVASDVSAYENAEQRDFINKTFKYLASNRPRHLELPEIYLWEKLYKIDNNNRAMEAKRRFFELDINPWQRTLDTHDKEYVPRAVRPDVPKNKNRFKKTYYP
Protein: Sesquiterpene synthase Cad (Beta-cadinene synthase) (Cf-Cad) (EC 4.2.3.-) (I1ZHA5)
Organism: Chamaecyparis formosensis (Formosan cypress) (Cupressus formosensis)
Function: Sesquiterpene synthase involved in the biosynthesis of volatile compounds (Ref.1). Mediates the conversion of (2E,6E)-farnesyl diphosphate (FPP) into beta-cadinene (Ref.1). Not active with geranyl diphosphate (GPP) and geranylgeranyl diphosphate (GGPP) as substrates (Ref.1).
Interaction partners:
Sequence:
MAEVGLSQNSYASANHDKKSEQQIRRRVAEFHPNVWEYEFLQSLSSPYGAPSYCERINILIEEIKMDIFDGLVGDGEKNMNPSAYDLLERFFVVDILQSLGIERHFKKEIKAVLDYTYKYWNDEKGISLASGNLIVDLNTNALGFKVLRLNEYYVSPDVFQNFQDEMGQFIDLENFKEDESKLRSLLSLYRASEICFPEENILKQAKMFASTCLRQAIEENRELVNKSQLIIEVEYIMKYPWTCRVPRWEVWNYIKIFRGDTDASMCMKGVYEMPSDKRTKILELAILDFNILQDQHHNELKILSKWWNETKVKELNFFRQRHVEFYFLYACGLYEKELSATRLCFAKVGALITLLDDIFDTYGTIDELVPFATALIKWDMSIMNHLPEYMKTCFQFAYKTYMEIATEAEKIHGPCVQKWMHDTWKTIILAQLQDAEWIANNYLPSLTEYLESSVPSTTVPVLSLFSMLLIDTIFPDDIIEKITKFQSCVAWGCRLVDDSKDFQDEKEHGESASWIECYMKENPGTTRKQALDHANMLIESNFEELIKHRIFYEYCIPSTCKRLYFDMYRSVAFIFKDIDGFSKSSKAIRDDIKKILVEPIYF
Protein: Uncharacterized protein (A0A1D8PUA3)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}.
Interaction partners:
- Glycerophosphocholine acyltransferase 1
- Uncharacterized protein
Sequence:
MSNTPIQGSSSKPNVAAEDYSRSSSRTNISSVRNRSATRMKKNSRPNLKRLGSVSHPQGLVYSVDDDINENDKDDSTKESEPKSDRDYLEGYNDALRALSNRKGRTSSGHLSIAGTPLRSPEEIATIESKLAKDLTDAEEQMRLLEDLDSGPTPNVTDEFVEPEDNNEDAGSIKSTSTVESLNLKERQNAINSTHPFGIKIWKPSLYKKKRSVATRAEEDIHDFDPRKPTARIYWGVKLTNIVWSLTAGLLICLICLLGAAFVFIFSGFAIERKSRPYVKALLKLGHYWLYPFGKFVLLNREQNYLDEDQLEGRTINEFHQWRLQEEGRLFFAPPRRYTGSESTRPLLKDHRGRPLRDAYSSLDDGIQEEEDEQDNDANDIKVRFFGRGDWSFGRIAFYVYFYGIIQPISFFIGILCWLIVFTIPMAKITNTMNDHMRRHPLALDYELEKDYYKRVERTPRKKNQVILLCTYRCCGFHYYKYTIDGTNIFFINLLSVVIFAILDYYFLKETMHWDSWITESNFIFCLSLFSIIPLAYFIGQAVASISAQSSMGVGAVINAFFSTIVEIFLYCVALNQAKGKLVEGSMIGSILGAVLLLPGLSMCGGAFKRKTQRYNPRSAGVSSTMLSYAMVVMFAPSIFYQMYGSYEMKCKDCTSPGVCGRCRFIQPTFVLDSLYSTVIKPFSLIVTVALFAAYVCGLFFTLRTHASLIWATTSHEPKRDDYFRSNSVVSMSTPTQTPKPTTPLPAKPEEDQGGGHDAPNWSRSKSTIILLGATILYAIIAEILVDNVDSILADFPINPKFLGLTVFALVPNTTEFLNAISFAVGGNVALSLEIGSAYALQVVLIQIPCLVLYSIYQNFENVEQTFTLIFPSWDIIATLISIYLFTYIYAEGKSNYFKGVILILIYVVVLSGFWFNDIIDSI
Protein: Sorting nexin 10 (Q8N5Z3)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Endomembrane system {ECO:0000256|ARBA:ARBA00029433}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00029433}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00029433}. Endosome {ECO:0000256|ARBA:ARBA00004177}.
Interaction partners:
Sequence:
MFPEQQKEEFVSVWVRDPRIQKEDFWHSYIDYEICIHTNSMCFTMKTSCVRRRYREFVWLRQRLQSNALLVQLPELPSKNLFFNMNNRQHVDQRRQGLEDFLRKVLQNALLLSYSSLHLFLQSHLNSEDIEACVSGQTKYSVEEAIHKFALMNRRFPEEDEEGKKENDIDYDSESSSSGLGHSSDDSSSHGCKVNTAPQES
Protein: Peripheral myelin protein 22 (PMP-22) (Protein CD25) (SR13 myelin protein) (Schwann cell membrane glycoprotein) (SAG) (P25094)
Organism: Rattus norvegicus (Rat)
Function: Might be involved in growth regulation, and in myelinization in the peripheral nervous system.
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Myelin proteolipid protein
- Laminin subunit beta-2
- Laminin subunit alpha-5
- Tyrosine-protein kinase Lyn
- Laminin subunit beta-1
- Laminin subunit gamma-1
- Integrin beta-4
- Integrin beta-1
- Integrin alpha-7
- Integrin beta
Sequence:
MLLLLLGILFLHIAVLVLLFVSTIVSQWLVGNGHRTDLWQNCTTSALGAVQHCYSSSVSEWLQSVQATMILSVIFSVLSLFLFFCQLFTLTKGGRFYITGVFQILAGLCVMSAAAIYTVRHSEWHVNNDYSYGFAYILAWVAFPLALLSGIIYVILRKRE
Protein: Nitrilase and fragile histidine triad fusion protein NitFhit (NFT-1 protein) [Includes: Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29) (Diadenosine 5',5'''-P1,P3-triphosphate hydrolase) (AP3A hydrolase) (AP3Aase) (Dinucleosidetriphosphatase); Nitrilase homolog (EC 3.5.-.-)] (O76464)
Organism: Drosophila melanogaster (Fruit fly)
Function: Cleaves A-5'-PPP-5'A to yield AMP and ADP.
Interaction partners:
- Uncharacterized protein
- S-adenosylmethionine decarboxylase proenzyme
Sequence:
MSTLVNTTRRSIVIAIHQQLRRMSVQKRKDQSATIAVGQMRSTSDKAANLSQVIELVDRAKSQNACMLFLPECCDFVGESRTQTIELSEGLDGELMAQYRELAKCNKIWISLGGVHERNDQKIFNAHVLLNEKGELAAVYRKLHMFDVTTKEVRLRESDTVTPGYCLERPVSTPVGQIGLQICYDLRFAEPAVLLRKLGANLLTYPSAFTYATGKAHWEILLRARAIETQCFVVAAAQIGWHNQKRQSWGHSMIVSPWGNVLADCSEQELDIGTAEVDLSVLQSLYQTMPCFEHRRNDIYALTAYNLRSKEPTQDRPFATNIVDKRTIFYESEHCFAFTNLRCVVKGHVLVSTKRVTPRLCGLDCAEMADMFTTVCLVQRLLEKIYQTTSATVTVQDGAQAGQTVPHVHFHIMPRRLGDFGHNDQIYVKLDERAEEKPPRTIEERIEEAQIYRKFLTDIS
Protein: Gamma-tubulin complex component (Q9VS91)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000256|RuleBase:RU363050}.
Interaction partners:
- Testis-specific gamma-tubulin ring protein 91
- Gamma-tubulin complex component
- Gamma-tubulin complex component 4 homolog
- Testis-specific gamma-tubulin ring protein 128
- Tubulin gamma-1 chain
- Gamma-tubulin complex component 3
- Tubulin gamma-2 chain
- Grip71
- Grip163
- NADH dehydrogenase 1 alpha subcomplex subunit 3
Sequence:
MNSDKSESDFANKVRFHLSKDELERQMRKIHDREESVDEKMRPSGSENSGHNCNTSSSSSLPRQESWIFESVGGYFLANENLAKMSLPCQEQLLMRDLIYAFSGVPSAYVKPDIQIDQISEMSAVDIAKIRFRLKKTFTGAFRALANETLPLIGYYISVQSYIEETNMSPNCGRTRLTLATALSDQLQDYYDLQSKLETDLQDKKLDLKDLVRQVRPWLPILKTFSNMASSARGNLTSAQVLTLLDQFYRDLKDTDIDLKERVNKILTSTSRAYMKIVQLWMQKGVLFDTQHEFFVEDTEPSSTMSSTLLAPEKCCHAYWAERYRLLPDRLPGFLLSQADDIFLAGKYLNILRQCNVSLKLLQRPLAYSQGDLGHEEIIKTSYELPAHKFLKVLVEEHNLPLHIRNLKSYFLLQEEGFSETFLHKCHEYLKYNVERLIPEKLQTLLAETLHKSNDFIKDNVRCQLKVCDVATLLGRQHKAQRAVEDEEEEEKESCSEQDPPEVLNLYGYEALALGYETKWPLSFIIYPELLEQLQMLQRVLFFLHYVKHHLTVLWQSPCEGTGLQLTNRSGKLRHRMLMCMLSLENHIIQDITEPRWQSLTLTVDKAKCIDEVLNKLESTVEECLRLGLLPTANTFVKSLYTLGHVCLNFCDFVESSIGEKSTKELEQEVVEYEEEFKSFLTSILELVSQLAKTKDIAERDSCKQLLKRLGELIEFSDLDKDQIASNI
Protein: Cell wall integrity and stress response component 1 (P87179)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane {ECO:0000269|PubMed:10759889}; Single-pass membrane protein {ECO:0000269|PubMed:10759889}.
Interaction partners:
- Rho1 guanine nucleotide exchange factor 2
- Rho1 guanine nucleotide exchange factor 1
- GTP-binding protein rho1
- Protein kinase C-like 2
- MAP kinase kinase skh1/pek1
- Uncharacterized aminotransferase C6B12.04c
Sequence:
MVFLNSSPFKGRLLFFVYLLIISTRLVAADMNTQYGCYLVDSSLTEQGTFTYLDPAYCYNNICGGSDNIAFVAIRNNQCYCGSTLTATEVSSSLCTTPCPGYGSLMCGGDLYWSVYLTGNGVLQTTVSSSSVSSTTSSSSSSSPSSSSTTTTTSPSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSVPITSSTSSSHSSSSSSSSSSSSSSRPSSSSSFITTMSSSTFISTVTVTPSSSSSSTSSEVPSSTAALALNASKASNHTSLNAGAIVGIVIGCVAFAVVMALCIFLYFYFRRFKIRMSDSANEGKYPSYASELDSRLDPAMMNRKSSESLADSQDYSRKILRVTNLN
Protein: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (Complex I-B8) (NADH-ubiquinone oxidoreductase B8 subunit) (Q9XWG2)
Organism: Caenorhabditis elegans
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004443}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004443}; Matrix side {ECO:0000256|ARBA:ARBA00004443}.
Interaction partners:
- Probable NADH dehydrogenase iron-sulfur protein 7, mitochondrial
- NADH-ubiquinone oxidoreductase 75 kDa subunit
- NADH dehydrogenase 1 alpha subcomplex subunit 9, mitochondrial
- Probable NADH dehydrogenase flavoprotein 2, mitochondrial
- NADH dehydrogenase iron-sulfur protein 5
- Acyl carrier protein
- Probable NADH dehydrogenase 1 alpha subcomplex subunit 12
- NADH-ubiquinone oxidoreductase chain 4
- NADH dehydrogenase 1 beta subcomplex subunit 9
- NADH dehydrogenase 1 beta subcomplex subunit 10
Sequence:
MSVRLAGTALREIRIHVCQKSPASAGVRAFIENDYVGIKKANPQFPILIREASGIVPRVFARYEHGVERVATLEDLSRENVKSTITQLASQK
Protein: At5g62720 (Integral membrane HPP family protein) (Q8GZ51)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Uncharacterized protein At5g13720)
- TLD-domain containing nucleolar protein
- Keratin-associated protein, putative
- Protein GLUTAMINE DUMPER 6
Sequence:
MASVPVRPLPLLRRNITSTTASKSSPMLANVSSRHSLGISTYDEFLKQIKTPATVNHRRRVSTVVASAGNLTAPSWDSWKPDKTAAATALLLSDVIWPAAGAFAAMALLGRMDQMLSPKGISMSVAPLGAVSAILFITPSAPAARKYNIFLAQIGCAAIGVVAFSVFGPGWLARSVALAASIAFMVITRANHPPAASLPLMFIDGAKFHHLNFWYALFPGAAACVILCLLQSIVCYLKENMKF
Protein: Mannuronan C5-epimerase (EC 5.1.3.37) (Poly(beta-D-mannuronate) C5 epimerase) (Q51371)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Catalyzes the epimerization of beta-D-mannuronate to alpha-L-guluronate during the synthesis of the linear polysaccharide alginate. In addition, is part of a periplasmic protein complex that protects alginate from degradation by AlgL by channeling the newly formed alginate polymer through a scaffold that transfers the alginate polymer through the periplasmic space to the outer membrane secretin AlgE.
Subcellular location: Periplasm {ECO:0000269|PubMed:8144447}.
Interaction partners:
- Alginate biosynthesis protein AlgK
- Alginate lyase
- Mannuronan synthase
- Mannuronan synthase
- Alginate biosynthesis protein AlgX
- Alginate production protein AlgE
- Probable alginate O-acetylase AlgJ
- Probable alginate O-acetylase AlgI
- GDP-mannose 6-dehydrogenase
- Alginate biosynthesis protein AlgA
Sequence:
MPDISLSIPRRRLPRLRPLAAAVLGAVLLHGQAWAAQPVEKPQPVPAQAGNEPGLTQGLKETGNYTVTTAPAEPLHLDPPKLPDLSGYTAAAVEAKIVRKPGGRASVQRMVQQQPLKEFTGGSNRLAEWVKRQRQMPQAIFIEGGYVNLAQLAGKLPASALEQVEPGVFVARLPIVVSQGATLDIDKQVKELRLSQERGAFLVNDGMLFVRDSKVTGWSESKKEPAWFKTPNEFRPFLISWGGAEVYLSNSTFTSFGYNASKAYGISISQYSPGMDKQMKRPRPKGWVIDSTIVDSWYGFYCYEADDLVVKGNTYRDNIVYGIDPHDRSHRLIIADNTVHGTRKKHGIIVSREVNDSFIFNNRSYENKLSGIVLDRNSEGNLVAYNEVYRNHSDGITLYESGDNLLWGNQVLANRRHGIRVRNSVNIRLYENLAAGNQLIGVYGHIKDLTNTDRNIALDPFDTKVSLIVVGGKLAGNGSGPLSVDSPLSLELYRVAMLAPTKSSGISLPGVLGEKQDQILDLLVRQDKAVLIDPVESQAELQD