wanglab/gogpt-training-data huggingface dataset:
Protein: SED5-binding protein 2 (SEC24-related protein 2) (P53953)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.
Subcellular location: Cytoplasm {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}.
Interaction partners:
- Protein transport protein SEC23
- Protein transport protein SEC13
- Protein transport protein SEC31
- COPII coat assembly protein SEC16
- SED5-binding protein 3
- Protein transport protein SEC22
- Protein transport protein SEC24
- GTPase-activating protein NEL1
- Small COPII coat GTPase SAR1
- Integral membrane protein SED5
Sequence:
MSHHKKRVYPQAQVPYIASMPIVAEQQQSQQQIDQTAYAMGNLQLNNRANSFTQLAQNQQFPGSGKVVNQLYPVDLFTELPPPIRDLSLPPLPITISQDNIVTPSEYSNVPYQYVRSTLKAVPKTNSLLKKTKLPFAIVIRPYLHLQDSDNQVPLNTDGVIVRCRRCRSYMNPFVVFINQGRKWQCNICRFKNDVPFGFDQNLQGAPINRYERNEIKNSVVDYLAPVEYSVREPPPSVYVFLLDVSQNAVKNGLLATSARTILENIEFLPNHDGRTRIAIICVDHSLHYFYVPLDDDYEVSDEDDEESDGEEEDEDEEEEDVDNSETIQMFDIGDLDEPFLPMPSDELVVPLKYCKNNLETLLKKIPEIFQDTHSSKFALGPALKAASNLIKSTGGKVEVISSTLPNTGIGKLKKRSEQGILNTPKESSQLLSCKDSFYKTFTIECNKLQITVDMFLASEDYMDVATLSHLGRFSGGQTHFYPGFNATSLNDVTKFTRELSRHLSMDISMEAVMRVRCSTGLRATSFFGHFFNRSSDLCAFSTMPRDQSYLFGISIEDSLMAEYCYLQVSTLLTLNTGERRIRVMTLALPTSESAREVFASADQLAITDFMTQNAVTKALNSSMYSARDFITKSLEDILNAYKKEISMSNINSVTSLNLCANLRMLPLLMNGLSKHIALRPGVVPSDYRASALNRLETEPLHYLIKSIYPTVYSLHDMPDEVGLPDFEGKTVLPEPINATISLFERYGLYLIDNSAELFLWVGGDAVPELLIDVFNTDTISQIPVGKSELPLLNDSPFNERLRRIIGRIRENNDTITFQSLYIIRGPSINEPANLNSEKDMASLRLWVLSTLVEDKVLNCASYREYLQSMKTSINR
Protein: Variant surface glycoprotein (VSG), putative (Q57TR3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
Sequence:
MHTIFPAALLAGYVVAFVAADATNTLAHDSTLWCHDIQYLEAILAAIDKEMNNRQKQLQVDAELIAKWKLAEAAAEQWHERRKYTALSVVIATLASKNSEAATEYLSAAAEAKKAINRRLEALQLVARTTSALKQTVTGAPQAASANAACQGSTEYASEAEFTCAPPEAGELKTAEVQTKLHTATHIKLTSFKALNELVAAPKITITATAGTTPFASPGQTPGTCQTSGGQNIAAGTNHVQYAVSSATVLKTQTPAAQPIDSDSERPEEPTAKKATVTAWLDIKFVTAALKNLKTAYNQKQIDLSQATHSTLAGLAGFKTVIANLFVGAEPPANNQETEYNNKIADIIKQTYGPEPGDFKRKFVTELANQDVKYTKAGNEQEKKLGALSKGADLSIALSFIINKRHESQLQKAAKAVSTVPKQNCTGKTKEKCKDACEWKGTDDKGECKPKDEEGQTNAAGTQGAETEGKDDKNNTNTTGSNSFVIHKAPLLLAVFVSIIYFLKISAQF
Protein: Fizzy-related 2 (GH18995p) (Q9W1F6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Anaphase-promoting complex subunit 2
- Cell division cycle protein 27 homolog
- Cell division cycle 16
- Mitotic spindle assembly checkpoint protein MAD2A
- Fizzy-related protein homolog
- Anaphase-promoting complex subunit 4
- Shattered
- Anaphase-promoting complex subunit 10
- Anaphase-promoting complex subunit 5
- Cyclosome subunit 8
Sequence:
MFQSEYQQRLLPGVAVGKKEDIDLRCIPTRAGNHWNRNFVNAPGDSNVYESSVYSCLLRNEFLDENITSLENCEQTAQVHAQTDDFRDRHNRIFGFASGSSSPVRTPFANISESSQRLLSIFKRPMRRLPRRPYKILDAPELQDDFYLNLIDWSSKNTLAVGLGCSVYLWSAVSGQVTRLCDFNNEDNLITAVSWHGEGRQVAIGTQSGYVTIWDAENQKQINRLEEHSARVTALAWCGNRLASGSRDRSILQRDIRNPPTHITRCLRGHKLEVCGLQWSPSNRYLASGGSDNRLLVWTDDWPEPIYAFDEHKAVVKALGWSPHKSGLLASGGGSADRCLRFWNVLTGKLVKCINTGAQISNLAWARDSRELVTTHGHAQPQVIAWRYPSLKQMARLSGHTQRVLHLSVSPDNESIVTGGADETLRFWTVFTKQKISKEPNSVLRLFKGIR
Protein: Transcription factor BTF3 (Q9VY34)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Nascent polypeptide-associated complex subunit alpha
- Uncharacterized protein, isoform A
- Venom allergen-1
- GH09281p
- Large ribosomal subunit protein eL31
- Large ribosomal subunit protein eL6
- FI01658p
- Large ribosomal subunit protein eL32
- Large ribosomal subunit protein eL21
- Small ribosomal subunit protein uS14
Sequence:
MDFNKRQNMEEVVRIGGKGSMRRKHKRIPSVAAVDEKRVQATLAKIPLKNISGIHELTIEFTDSSEVVVVMPKVQGISANGLLVVNGDFVRKSSTAGPSKMAKAAKAPKAPKAPKAPKTPMAPMAPMAPMAPMTPKPEAFSVKKPESEETIKVVAKKPKKLRNRVRPRNKKVQMMLSKNNEEAAMAGGDSEPKLSNGKSILISSEDGSDPDNEKVPSDESDVDRTVVCDKDSLGSFGDDSDGKEDDDSKESIYLSFYSDGYDS
Protein: Meiotic recombination protein rec14 (Q09150)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for formation of the rec12-mediated double-strand breaks (DSBs) that initiate meiotic recombination.
Interaction partners:
- Superkiller protein 3
- Putative ATP-dependent RNA helicase C550.03c
- Cell division control protein 73
- Tetratricopeptide repeat protein 1
- Meiotic recombination protein rec12
- RNA polymerase II-associated protein 1 homolog
- Mei4-dependent protein 2
- Meiotic recombination protein rec6
- Meiotic recombination protein rec7
- RNA polymerase-associated protein C651.09c
Sequence:
MRKEYLVSHIEENAHQADIYSLNVVAGNLWSASGDSKIKKWSIGDAEHSLVEEIDTPHKLGVHHLATSLDENVVVSCGFGQDVYVWNPETNEFRDLGNNAQHPSECWSSCISPDGQTIAFTSVDGRIAVWDNPSDCKISELDTKGKFGLCIDYSPNGRFIVSGHQTGQLFLISTETGRLFHVLSGHTSPVRSVAFSPGSTLLAAAGDSKMITIYDVLSGDQVGQLRGHAAWIFAVAFNPVGDLLLSADVEGKIKIWDIDTMECISTQSETDGAIWAVAWYKNGFIVAGADKSIRWYRAAATE
Protein: Dynamin-A (Q94464)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Function in membrane trafficking processes along the endo-lysosomal pathway.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:9880338}. Note=Found in association with endosomal and postlysosomal vacuoles.
Interaction partners:
- Rac guanine nucleotide exchange factor B
- Uncharacterized protein
- Dynamin-like protein B
- Endoplasmic reticulum transmembrane protein YET-like
- Mitochondrial division protein fszB
- Mitochondrial division protein fszA
Sequence:
MDQLIPVINKLQDVFNTLGSDPLDLPQIVVVGSQSSGKSSVLENIVGRDFLPRGSGIVTRRPLILQLTHLPIADDGSQTQEWGEFLHKPNDMFYDFSEIREEIIRDTDRMTGKNKGISAQPINLKIYSPHVVNLTLVDLPGITKVPVGDQPTDIEQQIRRMVMAYIKKQNAIIVAVTPANTDLANSDALQLAKEVDPEGKRTIGVITKLDLMDKGTDAMEVLTGRVIPLTLGFIGVINRSQEDIIAKKSIRESLKSEILYFKNHPIYKSIANRSGTAYLSKTLNKLLMFHIRDTLPDLKVKVSKMLSDVQGELSTYGDPLYDTKNSQGALLLQIITIFSSNFKDAIDGKLTDLSNNELYGGARISYIFNEIYSHCVNNIDPLEGISLNDIRTTMRNATGPRAALFIPEISFELLVKKQVVRLEEPSAQCVEYVYDELQRIVSQLEAKELSRFINLKARVIEVVNNLLQKHKVPTKTMIEHLIKIETAFINTSHPDFVGGEGIFESLYKKQQLQQQNHLQQLQDQYQQQQQQQQQQQQQNGINNNQKGDNGNMNVNQQNMNQQNMNQQNQSTNPFLQQQQQGQNKYPGGPPAQQQPNQQPNQLNKGPQNMPPNQSKPSSIPQNGPNNNNNNNNNNNRQDHQQGSFFSSFFRASPDPSLGQYGGANNSNNSNNPTSPINSSSNSGNNYNTFGGQQSSSSSSQQLQQSSQSQYKTSYNNNNNSSSNNSSYNRYQDDFYGRGDKLNQVPSIIKAPDDLTSKEKFETELIRELLISYFNIVKKNVKDSVPKSIMHFLVNQSKEHIQNELVAALYKEELFDELLEESPQISSKRKSCKAMIEILRKANEIINEIRDFRN
Protein: Probable cycloartenol-C-24-methyltransferase 1 (EC 2.1.1.41) (24-sterol C-methyltransferase 1) (Sterol 24-C-methyltransferase 1) (Q54I98)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of cycloartenol to form 24-methylene cycloartenol.
Interaction partners:
- Protein erg2 homolog
- Probable 3-beta-hydroxysteroid-Delta
- Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
- Squalene synthase
Sequence:
MNTQQRAMEGDLSRIVAISRKEKDAVSRNDKVDDTLNGYKELFKGNDDKAIQARKNNYTHMVNTFYDLATDFYEFGWGQSFHFATRHKYESFEASIARHEMYMAHQLGLFPGMKVIDIGCGVGGPMRTIARFSGANVVGLNNNEYQIQRGKRLNESAGLSHLCSFIKADFMHVPVEDNTYDCAYQIEATCHAPDLVGLYKEVFRIVKPGGLFGGYEWIMTNKFNPEDPVEVNIKKQIELGNGLPDLVKPAEIINAAKAAGFEVITAFDVAETSELPWYLPLSSGVSITGFLHTGVGRYLTGKFTQLLEIVKLAPAGSYNTNVWLQNAATFLVQGGEKQIFSPMFFLLCRKPSTD
Protein: BRCA2 OB1 domain-containing protein (Q4GZF5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- DNA repair protein RAD51 homolog
- Acyl carrier protein
- DNA repair protein, putative
- RecA family profile 1 domain-containing protein
- DNA repair protein RAD51 homolog 3
- RAD51/dmc1 protein, putative
- non-specific serine/threonine protein kinase
- Exonuclease, putative
- Endo/exonuclease Mre11
- BRCT domain-containing protein
Sequence:
MSHKKGRQGSNSGARQNSDTPQRNRTKCRSDAPKRQRSRSGESVQGKSPLQERETRIQPRRDRTYGTENGQESTAVQGNSTDVPTLFVSAAGKPITVSESSLQVARARMNTENGQESTAVQGNSTDVPTLFVSAAGKPITVSESSLQVARARMNTENGQESTAVQGNSTDVPTLFVSAAGKPITVSESSLQVARARMNTENGQESTAVQGNSTDVPTLFVSAAGKPITVSESSLQVARARMNTENGQESTAVQGNSTDVPTLFVSAAGKPITVSESSLQVARARMNTENGQESTAVQGNSTDVPTLFVSAAGKPITVSESSLQVARARMNTENGQESTAVQGNSTDVPTLFVSAAGKPITVSESSLQVARARMNTENGQESTAVQGNSTDVPTLFVSAAGKPITVSESSLQVARARMNTENGQESTAVQGNSTDVPTLFVSAAGKPITVSESSLQVARARMNTENGQESTAVQGNSTDVPTLFVSAAGKPITVSESSLQVARARMNTENGQESTAVQGNSTDVPTLFVSAAGKPITVSESSLQVARARMNTENGQESTAVQGNSTDVPTLFVSAAGKPITVSESSLQVARARMNTENGQESTAVQGNSTDVPTLFVSAAGKPITVSESSLQVARARMNTENGQESTAVQGNSTDVPTLFVSAAGKPITVSESSLQVARARMNTENGQESTAVQGNSTDVPTLFVSAAGKTVTVSESSLQVASANAASSAKPISGAGASLSKRTPRTHRKSASSSPLSSSKLARKPFVVPFAKNKGAVAKGVGEAVPSASHMPSSEGEGSEVGRTPRHLSFDIFTFRSLSMTVPPSIDEIVRGNFLFKQFGCSPELLKLLEIPAECEFIPSANFRKAMLTLGASPRGCPDAWCLQMLTSTLLKLRGLTLHIDPPLPVFSVAHTLLHMCFKYNHEYVEGKRPALRLIAEGDVQAASLVVVWVVSVSFEERLTPHTCTAVVSDGFYHVKVSLDIPLTNLVRNGTLRCGQKIVTCGARMLRRDCCSPLECKDEVLLSINYNCTQPVGPSSPLGLYHTCLPTLLPSAMDMLGGLVPCLKGRVERVLPPFFLEKTFKGARTGDTRGSTGGALKIVRSLLAQLSFQECMARGAVAPFEGKSDRQLSRLTSFLLSCERQGDVLLQIWDDCGANCPAGDLEEHSCDFPPEGAEIVVFSVTPSRFRPGHPFQRTTVLYSRSPLRYSIVSPPRKGFVRQPLRSAEDVSPKTETGDAIDFAGLFVGTKSVDTVNSHIIVALNDGWKPGCVPASYFMIDVPHATGSKEIVLALPSIPFTPVIVQNASFIRCAEDLGPDCIHVLANEYTKVYSRPAEPLLRGVVESLGKIRGMAKSSRPIIARSEELLRMRTLSEEARADICRLSRELVGGDELPNPAATAQPSPRYQLRQEASTPVEQSITVSETSAARTLSSEEEQVEDLRSSNVKASPRRHVFGNIVGFRLLKCQGSDKPECIEILGGRPSTLVSGSGKFVVSPSDFSQSLVYFEADIQFGATAKQCAQTKVRSPSVLHSLLEQCIPLKRACALTVDEIFADYYLARIKQLEDWQTPHEECWWRLLTQSHVVEITSDVSGTPPEELVGLQWLSNEWKMLLNILSGSLKHCLFMFSVEGSEMVRATFIKEQCSVADLMRE
Protein: NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (EC 7.1.1.2) (Complex I-75kD) (CI-75kD) (P28331)
Organism: Homo sapiens (Human)
Function: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for catalysing the entry and efficient transfer of electrons within complex I. Plays a key role in the assembly and stability of complex I and participates in the association of complex I with ubiquinol-cytochrome reductase complex (Complex III) to form supercomplexes.
Subcellular location: Mitochondrion inner membrane {ECO:0000305|PubMed:12611891, ECO:0000305|PubMed:30879903}; Peripheral membrane protein {ECO:0000250|UniProtKB:P15690}; Matrix side {ECO:0000250|UniProtKB:P15690}.
Interaction partners:
- NADH dehydrogenase iron-sulfur protein 4, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 7
- NADH dehydrogenase 1 beta subcomplex subunit 7
- NADH dehydrogenase 1 alpha subcomplex subunit 11
- NADH dehydrogenase 1 alpha subcomplex subunit 1
- Cytochrome c1, heme protein, mitochondrial
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH dehydrogenase iron-sulfur protein 3, mitochondrial
- NADH-ubiquinone oxidoreductase chain 1
- NADH dehydrogenase 1 beta subcomplex subunit 9
Sequence:
MLRIPVRKALVGLSKSPKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQIPRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMMFGNDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQRLTEPMVRNEKGLLTYTSWEDALSRVAGMLQSFQGKDVAAIAGGLVDAEALVALKDLLNRVDSDTLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRKSWLHNDLKVALIGSPVDLTYTYDHLGDSPKILQDIASGSHPFSQVLKEAKKPMVVLGSSALQRNDGAAILAAVSSIAQKIRMTSGVTGDWKVMNILHRIASQVAALDLGYKPGVEAIRKNPPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPIADVILPGAAYTEKSATYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSEIAGMTLPYDTLDQVRNRLEEVSPNLVRYDDIEGANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQAVEEPSIC
Protein: Rhino (Q49BK5)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MSRNHQRPNLGLVDAPPNDHVEEYVVEKILGKRFVNGRPQVLVKWSGFPNENNTWEPLENVGNCMKLVSDFESEVFRLHRKAAAKSVGKSKSSPSSSGPLITENGTSSSKKTQQHSKSVQAKNTAGMSKMDQKKGKNIKKTAGKIKDIENYPKTQMPITSQVSTDSTEVFDGSPSATTTNMIKSPRIQSLFSDLNLIEPTKDKDVGDTSLKTHPKSRRPIEFPQREDAPLSSKHVSPMLIRKESQPLQSSCTDDSDLGESSSSMSLPTVSSTSSEKSIKVTKSEPKTLGQIKFSSRSSDGGHAASSLGAPKEGDIGLDLSGSDSMDSEVESMRRCPRRKRKKTYPNWKFPEITKPFGVNRGLDLDEILHCYQMNDDLFMFVTWKGCSSIDAVHINDIKEAYPLQIIKYFESLRIIVPK
Protein: Antileukoproteinase (ALP) (Secretory leukocyte protease inhibitor) (P97430)
Organism: Mus musculus (Mouse)
Function: Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. Modulates the innate immune response after bacterial infection. Contributes to regulate the inflammatory and immune responses to the intracellular parasite L.major. Down-regulates responses to bacterial lipopolysaccharide (LPS). Plays a role in regulating the activation of NF-kappa-B and inflammatory responses. Has antimicrobial activity against mycobacteria, but not against salmonella. Contributes to normal resistance against infection by M.tuberculosis. Required for normal resistance to L.major. Required for normal wound healing, probably by preventing tissue damage by limiting protease activity. Together with ELANE, required for normal differentiation and proliferation of bone marrow myeloid cells (By similarity).
Subcellular location: Secreted {ECO:0000269|PubMed:18322212, ECO:0000269|PubMed:9126337}.
Interaction partners:
- Neutrophil elastase
- Progranulin
- Myeloblastin
- Lactotransferrin
- Cathepsin G
- Neutrophil gelatinase-associated lipocalin
Sequence:
MKSCGLLPFTVLLALGILAPWTVEGGKNDAIKIGACPAKKPAQCLKLEKPQCRTDWECPGKQRCCQDACGSKCVNPVPIRKPVWRKPGRCVKTQARCMMLNPPNVCQRDGQCDGKYKCCEGICGKVCLPPM
Protein: S-(+)-linalool synthase, chloroplastic (OsLIS) (EC 4.2.3.25) (Q6ZH94)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Involved in monoterpene (C10) biosynthesis. The major product is S-(+)-linalool. Linalool production is induced by jasmonate in response to pathogen attack, it possesses antibacterial activity and is important for resistance to the bacterial blight pathogen Xanthomonas oryzae pv. oryzae (Xoo). Plants over-expressing linalool synthase display enhanced resistance to Xoo.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:23889289}.
Interaction partners:
- Mevalonate kinase
- Alkyl transferase
- Os02g0668100 protein
- Os01g0248701 protein
- Os08g0193100 protein
- Solanesyl-diphosphate synthase 1, mitochondrial
- Os03g0428200 protein
- Squalene synthase
- Squalene synthase
- Os10g0489500 protein
Sequence:
MVCHVFSSFSSSLIRVLEAPLLLPAASASSSSSSSPASRSGGRRRRAAHVRPSPAIYPGRQELASHSSMLPTDFDIKVLIERHEALTDDVQEMLQHQRRRHQKTASGGRERIATVDHLRRLCMDHYFQDEVDDAMDACLLEELAHGGDLLDATLAFRLMREAGHHVSADEVLGRFTDDNGEFRLDYRKDIRGLLSLQDISHMNIGQEASLCKAKEFSTRNLESAINYLEPNLARYVRQSLDHPYHVSLNQYKARHHLSYLQTLPIRCTAMEELALADFQLNKLLHQMEMQEIKRWWMDLGLAQEIPVARDQVQKWFVWMMTAIQGASLSRCRIELTKIVSFVYIVDDIFDLVGTREELSCFTQAIRMWDLAAADSLPSCMRSCFRALHTVTNDIADMVEREHGVNPINHLKKAWAMLFDGFMTETKWLSAGQVPDSEEYLRNGVVTSGVPLVFVHLLFMLGHDVSQNAAEFVDHIPPVISCPAKILRLWDDLGSAKDEAQEGLDGSYKELYLKENPGLAAGEAEEHVRRLIAGEWEELNRECFSASPSRSSPATTFPAGFTQAALNAARMVGVMYGYDGERRLPVLDDYVRMLLF
Protein: Zinc-finger homeodomain protein 1 (AtZHD1) (Homeobox protein 25) (AtHB-25) (Zinc finger homeodomain transcription factor 2) (Q9FKP8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Putative transcription factor.
Subcellular location: Nucleus {ECO:0000305}. Note=Interactions with MIF proteins prevent nuclear subcellular location and leads to a scattered repartition throughout the cytoplasm.
Interaction partners:
- B3 domain-containing protein At3g18960
- Chaperone protein ClpD, chloroplastic
Sequence:
MEFEDNNNNNDEEQEEDMNLHEEEEDDDAVYDSPPLSRVLPKASTESHETTGTTSTGGGGGFMVVHGGGGSRFRFRECLKNQAVNIGGHAVDGCGEFMPAGIEGTIDALKCAACGCHRNFHRKELPYFHHAPPQHQPPPPPPGFYRLPAPVSYRPPPSQAPPLQLALPPPQRERSEDPMETSSAEAGGGIRKRHRTKFTAEQKERMLALAERIGWRIQRQDDEVIQRFCQETGVPRQVLKVWLHNNKHTLGKSPSPLHHHQAPPPPPPQSSFHHEQDQP
Protein: Nucleoside diphosphate kinase (NDP kinase) (EC 2.7.4.6) (AnNDK) (NDK) (Q8TFN0)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
Interaction partners:
- Small ribosomal subunit protein uS7m
- 37S ribosomal protein S16
- Ribosomal protein S15, putative
- 40S ribosomal protein S2, putative
- Mitochondrial 40S ribosomal protein MRP2, putative
- Small ribosomal subunit protein uS10m
- Small ribosomal subunit protein mS29
- Small ribosomal subunit protein bS6m
- Ribonucleoside-diphosphate reductase
- 37S ribosomal protein S12
Sequence:
MTSEQTFIAIKPDGVQRGLVGPIISRFENRGFKLAAMKLTSPSRSLLEQHYSDLKEKPFFPGLVTYMLSGPIVAMVWEGKDVVKTGRTILGATNPLASAPGTIRGDFAIDVGRNVCHGSDSVESAKKEIGLWFTPEEIQNYKLNAFGWIYEKE
Protein: Inner membrane protein YeeR (P76361)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- Antigen 43
- UPF0758 protein YeeS
- Uncharacterized protein YeeT
Sequence:
MLQIVGALILLIAGFAILRLLFRALISTASALAGLILLCLFGPALLAGYITERITRLFHIRWLAGVFLTIAGMIISFMWGLDGKHIALEAHTFDSVKFILTTALAGGLLAVPLQIKNIQQNGITPEDISKEINGYYCCFYTAFFLMACSACAPLIALQYDISPSLMWWGGLLYWLAALVTLLWAASQIQALKKLTCAISQTLEEQPVLNSKSWLTSLQNDYSLPDSLTERIWLTLISQRISRGELREFELADGNWLLNNAWYERNMAGFNEQLKENLSFTPDELKTLFRNRLNLSPEANDDFLDRCLDGGDWYPFSEGRRFVSFHHVDELRICASCGLTEVHHAPENHKPDPEWYCSSLCRETETLCQEIYERPYNSFISDATANGLILMKLPETWSTNEKMFASGGQGHGFAAERGNHIVDRVRLKNARILGDNNARNGADRLVSGTEIQTKYCSTAARSVGAAFDGQNGQYRYMGNNGPMQLEVPRDQYAGAVETMRNKIREGKVEER
Protein: BBSome interacting protein 1 (J3QMK2)
Organism: Mus musculus (Mouse)
Interaction partners:
- BBSome complex member BBS7
- BBSome complex member BBS1
- Protein PTHB1
- BBSome complex member BBS2
- BBSome complex member BBS5
- Tetratricopeptide repeat protein 8
- BBSome complex member BBS4
- Chaperonin-containing T-complex member BBS12
- BBSome complex assembly protein BBS10
Sequence:
MAEVKSMFREVLPKQGQLSVEDVTTMVLCKPKLLPLKSLTLEKLEKMQQAAQDTVRQQEMAEKATSK
Protein: cGMP-dependent protein kinase interacting domain-containing protein (G5EG29)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MGQDDEDDAHMLQAKQQITFNVVNKRKDQLRRWQSSEMNAEAARRTKRPKVQFQDSDIFLSACMSGDEEEVEELLNKGANINTCTVDGLTALHQSVIDSKPEMVRFLCEKGADVNAQDNEGWTPLHAAACCGNVAIVRYLCQHGADLSIVNSDKELALDLAVDEQCRDYLDDDYKRQMIDLDACRDQELQTMLKDVNMWMSQGEYRDIPHHRTGGTAMHVAAGRGYTQLLELLIKAGGNVRAQDVEGWTPLHAAAHWAERDACKILLENGAELSDLTFTGADVLGVADKECIDYLVELADTVKVQNKRKSPGSGSQPPTSILQEKNHRMPSHEEHVLTSERKRDLQHKDQHSENEFLHSHPSTASVGSTTSSNTNTTTTTIVIGENDISAAQKDSRESSKESAVDDEEYVAEDEMEEAEEDEEEEDVEEEEEEKSEAELKNGKEISPLRSETTSSRSISITRSLDGYTDRSSSGRETSAEMSEAASSASTGTTSSSSRFTSSTPSSQRSAAGSVHTETPRSSMENSSSVGSGDQNVSATIPIVPLSAPPKAVHQSPSSWINRGVPLSSRSSTSSVTRSSSTPVSEIISPPSSIHSQLSFPSVSNTTTTTATVAPTSSTVPSTPVSNVMAATISSTAKNTPSPAGSVTTINATFSKPSRWQSKTVTESEAERRNNSRMQRQHRRSTQGVTKEQLEEASKFATDEVARRNSQVLSTYPNSGLSISRSNRRATGPVNPEDLAPAMSLRLATAQPYSPASVRSNAGTLPTMTSRFSEKAQSLPPASNGMSSTQPLSTRSAIVAGLSSAPSMRTTAPLSSTATSSRFMPSSSLSSNGSSANQQPSSIYGLQSRPTETNLNYKALFEKERSECERLRREMEEMRRSQTADSYRGASTQLAWRARNASPSAQPHNLSVAKSTSLASFDENERRSMERKISDLELQLKTATNLRMENQRLKEENGALVRVISKMTI
Protein: Non-structural protein V (Q9EMA9)
Organism: Measles virus (strain Edmonston) (MeV) (Subacute sclerose panencephalitis virus)
Function: Plays an essential role in the inhibition of host immune response. Prevents the establishment of cellular antiviral state by blocking interferon-alpha/beta (IFN-alpha/beta) production and signaling pathway. Interacts with host IFIH1/MDA5 and DHX58/LGP2 to inhibit the transduction pathway involved in the activation of IFN-beta promoter, thus protecting the virus against cell antiviral state. Blocks the type I interferon signaling pathway by interacting with host TYK2 and thereby inhibiting downstream STAT1 and STAT2 phosphorylation. Moderately affects the type II interferon signaling (By similarity).
Subcellular location: Host cytoplasm {ECO:0000250}.
Interaction partners:
Sequence:
MAEEQARHVKNGLECIRALKAEPIGSLAIEEAMAAWSEISDNPGQERATCREEKAGSSGLSKPCLSAIGSTEGGAPRIRGQGPGESDDDAETLGIPPRNLQASSTGLQCYYVYDHSGEAVKGIQDADSIMVQSGLDGDSTLSGGDNESENSDVDIGEPDTEGYAITDRGSAPISMGFRASDVETAEGGEIHELLRLQSRGNNFPKLGKTLNVPPPPDPGRASTSETPIKKGHRREISLIWNGDRVFIDRWCNPMCSKVTLGTIRARCTCGECPRVCEQCRTDTGVDTRIWYHNLPEIPE
Protein: Protein nipi-4 (No induction of peptide after drechmeria infection protein 4) (O16262)
Organism: Caenorhabditis elegans
Function: Pseudokinase which plays a role in resistance to fungal infection by promoting expression of antimicrobial peptides (nlp-29, nlp-31, nlp-34, cnc-1, cnc-2 and cnc-4) in the epidermis. In addition, up-regulates nlp-29 expression upon physical wounding and in response to phorbol ester PMA treatment.
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- E3 ubiquitin-protein ligase CBL
- Sex muscle abnormal protein 5
- SHC-transforming protein homolog 1
- Tensin homolog
- non-specific serine/threonine protein kinase
- Tyrosine-protein phosphatase non-receptor type ptp-2
- Cell death abnormality protein 2
- Sodium-dependent transporter snf-12
Sequence:
MELDHTPPPSVLNDNCSASYMTPYATVIAMSGLYLLAIFYFCKKSKKMCQPMSDSIYPYQKRLTQLERELKNYLIDEESIEVDDFQIGQTADGFIFRGGVFPKTRNRFNAKVTTAVKISFPIVSKSISLLEDALRLSKLDHPNLIRLLAVSQLSFTVFRPMIALEWLPGGTLADYFQFKVREKDDSERSPIQLKDMLSILYQVSQALKYIHSQLDEFGQELTHGRIFTRNVLVTEPDLRKCEVKLGDFGDAPMGLEYSTPIIAYMPPEILCCAERIPPHRPENDVWMFGVFIWECLTLGAQPHFRKSVEEIKKSFRLPDRGLSCPPTCPLDVWTLVSDCLSEPHMRPRFASTTNASITSRLSELHHIVSPALFLYAIPNQSVCTCIEHHCQSVIHY
Protein: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (Q7KJN6)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
DHNPPTIELIQRFCSDVDMWLKEDSSNVVAVHCKAGKGRTGTMICAYLVFSGIKKSADEALAWYDEKRTKDRKGVTIPSQRRYVQYFSKLVCSSVPYSKVSLNVCEIRFSESSCVQNLGMVECSISVLHDSATENAKPDRLKTLPIDFQKSFVLTIKPSIPVSGDVKFELTKKSPDKIICHFWLNTFFVRNYSPCESDGTVNKYIHTLSKSEIDDVHKDSEHKRFSEEFKISIVFEAENFSNDVQAEASEKERNENVLNFERSDYDSLSPNCYAEKKVLTAIVNDNTTKSQTIETLDHKDIVTKIQYDTSTNSKNTSTACKRKQPNSKTLLPSLNDSTKEEIKRNHIFNQPSIKKTDLIKWQNSEVHITRSINENKNINYNSYITCKQSSPKFNCGTEDGEEDWESGESTYL
Protein: Aspartate-beta-hydroxylase (A0A096MK70)
Organism: Rattus norvegicus (Rat)
Subcellular location: Sarcoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004157}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004157}.
Interaction partners:
Sequence:
MAPRKNAKGGGGNSSSSGSGSGSGSPSTGSSGSSSSPGARREAKHGGHKNGRRGGISGGSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLGKLGVYDADGDGDFDVDDAKVLLGLKERSTSERTFPPEEAETQAELEEQAPEGAEAQNVEDEVKEQIQSLLQESVHTDHDLEADGPAGEPQSEVEDFLTATDSDDRFEALEPGTVHEDTEDSYHVEETASQNHPNDAEEVMSEQESSDHGEAVTDDGLQQHAEEVRHEDYDEPVYEPSENERIEISDNAIDDSNIISEEINVASVEEQQDTPPDT
Protein: RNA helicase (EC 3.6.4.13) (Q65XX1)
Organism: Caenorhabditis elegans
Interaction partners:
- ATP-dependent RNA helicase cgh-1
- Tr-type G domain-containing protein
- m7GpppN-mRNA hydrolase dcap-2
- Protein LSM14 homolog car-1
Sequence:
MPAGGVFYNGFANGTPSNNGYAIQQPMVPGMGQMMGAPHAGFVPSPYFQGQPQQQQHFKMGYSENFENFDENGSSGYNNFADSGNGFNNNGAESNQWGGAPAEYSESNLFHRTDSGINFDKYENIPVEVSGDSVPAAIEHFNEAGFGPAVMENVNRSGYSKPTPVQKHSIPTLLANRDLMSCAQTGSGKTAAFLLPIIQHILAGGPDMVKPPAFTNGRRTYYPCALVLSPTRELAIQIHKEATKFSYKSNIQTAILYGGRENYRDQVNRLRAGTHILIATPGRLIDIIEQGFIGLAGCRYLVLDEADRMLDMGFEPQIRKIVGQGMPPKTARTTAMFSATFPKEIQVLAKDFLKDNYIFLAVGRVGSTSENIEQRLLWVNEMEKRSNLMEILMNEHSENLVLVFVETKRGANELAYFLNRQQIRSVSIHGDLKQIERERNLELFRSGQCPILVATAVAARGLDIPNVRHVINYDLPGDSDEYVHRIGRTGRCGNLGIATSFFNDKNRGIGRDLKNLIVESNQEVPEWLHQVAAEGRIGGGQRGGNRRFGATDYRVGRGGGGSFGGNFSNYNSGGATGGFGSGPAYGGSFGGGAPRRPFTNGGFGAHSSLSSTSNSGGGGGFSGPRRGGFNSGMNRQGGGGGGFYSNPGQAPIDHWQAPQA