wanglab/gogpt-training-data huggingface dataset:
Protein: LITAF domain-containing protein (NMDA-type ionotropic glutamate receptor NMR-1) (G5EGQ9)
Organism: Caenorhabditis elegans
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034100}. Postsynaptic density {ECO:0000256|ARBA:ARBA00034105}.
Interaction partners:
- NMDA-type ionotropic glutamate receptor NMR-2
- Disks large homolog 1
- Calcium/calmodulin-dependent protein kinase type II
- Protein lin-2
- Probable vesicular glutamate transporter eat-4
- Glutamate receptor 1
- Rab-3-interacting molecule unc-10
- Nuclear hormone receptor family member fax-1
- Neuronal immunoglobulin domain-containing protein rig-3
- Neuronal calcium sensor 1
Sequence:
MFRISVIFIWIFLQLGYTIDYKVSVLIVSEPNQETFKELKVSVTAAFVEVFGSTSYHLGNDTISAAFVDAKSGDNRLELTQDIVCSQMLNHSLASVIFSPLLTSSSRFIDLVTSSAYTLSFYKLPVVGVMVRDAEFSKKNIYPTFVRPTAPLSDEAFVFLHMLLSLKYRQVVVLSVKRDINADQFVEEFEKRRVEFKIIVQRYIEVELNENLNDTLAESFEEVTSNIIVLFAKKDDAVRIFANAGDLTGKGKVWIVSESAGEAHNVPNGSLGCRLGQTAFSVLRDSFSILKSAMETIFRESKIDIFPPVECDRDSVDAEWNSLQAPALLNEICGTSTSRVHFNDKCERIGVEYDIINFHMERKQVGNMVGDILRLDEDSIEWAGGTKPLEISLPKHLRVVTVADPPFVYTTPIGSPSQCAELGNTVVEWSIFDKIVVSGPWYSCPLTLENSTEYFCCAGLAIDLLSNLSLPEANNSIDTSFTFSLHLNESYGVVQASETTGITISGVIGELDGDTADMAIGGITINPERERIVDFTEPWLYHGIRILEKNIPRDSPMQSFLQPLQSSLWTALFISVILVGLAIYCLDFKSPFERFYQADKEMEQDLKKEFELWIGKDADENVNFGEAMWFVWGVLLNSGVSEKTPRSCSARVLGIVWCGFCMIMVASYTANLAAFLVLDQPEKGLTGVTDPRLRNPSANFSFGTVLNSNVYQYFKRHVELSSMFRKMEPHNVRRASEAVHSLLNGSLDAFIWDSTRLEFEAARHCELRTRGSLFGRSAYGIGLQKNSPWTPHITSAILRMSESGVMEKLDQKWIDRGGPNCVVEAHKSPARLGLVNMKDIFILVSSGVALGIFLSFVEVSYGRRLADKGRRRRIVTRYFQKWHDLTLGKKRRPYRLKYNLDRMIVRRGFSGLERCSFQELRERRQIRGLPTSKVDPYCFWPDLDFKDKPLVLFCSRCRNIVESDVHRETGLFAFLSCFLFAILFLWPCSPLPCFLSSFSDFVHICPLCSHIMGRFRRARSTRFYV
Protein: U3 small nucleolar RNA-associated protein 4 (U3 snoRNA-associated protein 4) (U three protein 4) (U3 protein 4 required for transcription) (t-UTP4) (Q06679)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs).
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:12068309}.
Interaction partners:
- U3 small nucleolar RNA-associated protein 20
- Nucleolar protein 6
- U3 small nucleolar RNA-associated protein 6
- Ribosomal RNA-processing protein 9
- Essential nuclear protein 1
- U3 small nucleolar RNA-associated protein 8
- KRR1 small subunit processome component
- Nucleolar protein 58
- Ribosome biogenesis protein ENP2
- U3 small nucleolar RNA-associated protein 16
Sequence:
MSSSLLSVLKEKSRSLKIRNKPVKMTSQERMIVHRCRFVDFTPATITSLAFSHKSNINKLTPSDLRLAIGRSNGNIEIWNPRNNWFQEMVIEGGKDRSIEGLCWSNVNGESLRLFSIGGSTVVTEWDLATGLPLRNYDCNSGVIWSISINDSQDKLSVGCDNGTVVLIDISGGPGVLEHDTILMRQEARVLTLAWKKDDFVIGGCSDGRIRIWSAQKNDENMGRLLHTMKVDKAKKESTLVWSVIYLPRTDQIASGDSTGSIKFWDFQFATLNQSFKAHDADVLCLTTDTDNNYVFSAGVDRKIFQFSQNTNKSQKNNRWVNSSNRLLHGNDIRAICAYQSKGADFLVSGGVEKTLVINSLTSFSNGNYRKMPTVEPYSKNVLVNKEQRLVVSWSESTVKIWTMGTDSSTEQNYKLVCKLTLKDDQNISTCSLSPDGQVLVVGRPSTTKVFHLQPVGNKLKVTKLDNDLLLRTSTKLVKFIDNSKIVICSCEDDVFIVDLESEEDEKPQEVELLEVTSTKSSIKVPYINRINHLEVDQNIAVISRGCGVVDILDLKARISKPLARLNNFITAVHINTSRKSVVVITADNKIYEFNMNLNSEAENEDSESVLTQWSKNNTDNLPKEWKTLKENCVGIFSDIENSSRLWFWGATWISRIDFDVDFPINKRRKQKKRTHEGLTITDESNFMNDEEDDEDDDIDMEISENLNVLLNQGNKIKSTDVQRNEESSGHFFFTDKYKPLLFVDLISSNELAIIERNPLTFHSKQKAFIQPKLVF
Protein: Zinc finger protein 346 (B7Z4J8)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEYPAPATVQAADGGAAGPYSSSELLEGQEPDGVRFDRERARRLWEAVSGAQPVGREEALSKRLTNPFLVASTLALHQNREMIDPDKFCSLCHATFNDPVMAQQHYVGKKHRKQETKLKLMARYGRLADPAVTDFPAGKGYPCKTCKIVLNSIEQYQAHVSGFKHKNQSPKTVASSLGQIPMQRQPIQKDSTTLED
Protein: Clathrin heavy chain 1 (Q0WNJ6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (By similarity). Mediates endocytosis and is required for a correct polar distribution of PIN auxin transporters.
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:P25870}; Peripheral membrane protein {ECO:0000250|UniProtKB:P25870}; Cytoplasmic side {ECO:0000250|UniProtKB:P25870}. Membrane, coated pit {ECO:0000250|UniProtKB:P25870}; Peripheral membrane protein {ECO:0000250|UniProtKB:P25870}; Cytoplasmic side {ECO:0000250|UniProtKB:P25870}. Note=Cytoplasmic face of coated pits and vesicles. {ECO:0000250|UniProtKB:P25870}.
Interaction partners:
- Beta-adaptin-like protein B
- Clathrin interactor EPSIN 1
- AP-2 complex subunit alpha-1
- Clathrin interactor EPSIN 2
- Clathrin interactor EPSIN 3
- ENTH/VHS family protein
- AP-2 complex subunit alpha-2
- AP-2 complex subunit sigma
- AP-2 complex subunit mu
- AP-1 complex subunit gamma-2
Sequence:
MAAANAPIIMKEVLTLPSVGIGQQFITFTNVTMESDKYICVRETAPQNSVVIIDMNMPMQPLRRPITADSALMNPNSRILALKAQVPGTTQDHLQIFNIEAKAKLKSHQMPEQVAFWKWITPKMLGLVTQTSVYHWSIEGDSEPVKMFDRTANLANNQIINYKCSPNEKWLVLIGIAPGSPERPQLVKGNMQLFSVDQQRSQALEAHAASFAQFKVPGNENPSILISFASKSFNAGQITSKLHVIELGAQPGKPSFTKKQADLFFPPDFADDFPVAMQVSHKFNLIYVITKLGLLFVYDLETASAIYRNRISPDPIFLTSEASSVGGFYAINRRGQVLLATVNEATIIPFISGQLNNLELAVNLAKRGNLPGAENLVVQRFQELFAQTKYKEAAELAAESPQGILRTPDTVAKFQSVPVQAGQTPPLLQYFGTLLTRGKLNSYESLELSRLVVNQNKKNLLENWLAEDKLECSEELGDLVKTVDNDLALKIYIKARATPKVVAAFAERREFDKILIYSKQVGYTPDYMFLLQTILRTDPQGAVNFALMMSQMEGGCPVDYNTITDLFLQRNLIREATAFLLDVLKPNLPEHAFLQTKVLEINLVTFPNVADAILANGMFSHYDRPRVAQLCEKAGLYIQSLKHYSELPDIKRVIVNTHAIEPQALVEFFGTLSSEWAMECMKDLLLVNLRGNLQIIVQACKEYCEQLGVDACIKLFEQFKSYEGLYFFLGSYLSMSEDPEIHFKYIEAAAKTGQIKEVERVTRESNFYDAEKTKNFLMEAKLPDARPLINVCDRFGFVPDLTHYLYTNNMLRYIEGYVQKVNPGNAPLVVGQLLDDECPEDFIKGLILSVRSLLPVEPLVAECEKRNRLRLLTQFLEHLVSEGSQDVHVHNALGKIIIDSNNNPEHFLTTNPYYDSKVVGKYCEKRDPTLAVVAYRRGQCDEELINVTNKNSLFKLQARYVVERMDGDLWEKVLTEENEYRRQLIDQVVSTALPESKSPEQVSAAVKAFMTADLPHELIELLEKIVLQNSAFSGNFNLQNLLILTAIKADPSRVMDYINRLDNFDGPAVGEVAVDAQLYEEAFAIFKKFNLNVQAVNVLLDNVRSIERAVEFAFRVEEDAVWSQVAKAQLREGLVSDAIESFIRADDTTQFLEVIRASEDTNVYDDLVRYLLMVRQKVKEPKVDSELIYAYAKIERLGEIEEFILMPNVANLQHVGDRLYDEALYEAAKIIYAFISNWAKLAVTLVKLQQFQGAVDAARKANSAKTWKEVCFACVDAEEFRLAQICGLNIIIQVDDLEEVSEYYQNRGCFNELISLMESGLGLERAHMGIFTELGVLYARYRYEKLMEHIKLFSTRLNIPKLIRACDEQQHWQELTYLYIQYDEFDNAATTVMNHSPEAWEHMQFKDIVAKVANVELYYKAVHFYLQEHPDIINDLLNVLALRLDHTRVVDIMRKAGHLRLIKPYMVAVQSNNVSAVNEALNEIYAEEEDYDRLRESIDLHDSFDQIGLAQKIEKHELVEMRRVAAYIYKKAGRWKQSIALSKKDNMYKDCMETASQSGDHDLAEQLLVYFIEQGKKECFATCLFVCYDLIRPDVALELAWINNMIDFAFPYLLQFIREYSGKVDELIKDKLEAQKEVKAKEQEEKDVMSQQNMYAQLLPLALPAPPMPGMGGGGYGPPPQMGGMPGMSGMPPMPPYGMPPMGGY
Protein: Ryanodine receptor 3-like protein (A4KUJ3)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Interaction partners:
Sequence:
VEMILKFFDMFLKIKDLTTSDNFREYDPDNKGVISKKDFQKSMENQKQYTQSEIEFLLSCAEADENDMFNYEEFVERFHEPAKDIGFNIAVLLTNLSEHMPHDPRLATFLEPAESVLNYFEPYLGRIEIMGGGKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGESEKMEMFVNFCEDTIFEMQLASQISEPEVAERPEEEEEEVHNLLEELAEQEEERELEASSAFTMVCVAAKKKISNFRQMLTFKTLKKQYKKTKKLSMKEVI
Protein: Anion exchange protein 2 (AE 2) (Anion exchanger 2) (Band 3-related protein 2) (B3RP-2) (Non-erythroid band 3-like protein) (Solute carrier family 4 member 2) (P23347)
Organism: Rattus norvegicus (Rat)
Function: Sodium-independent anion exchanger which mediates the electroneutral exchange of chloride for bicarbonate ions across the cell membrane. Plays an important role in osteoclast differentiation and function (By similarity). Regulates bone resorption and calpain-dependent actin cytoskeleton organization in osteoclasts via anion exchange-dependent control of pH (By similarity). Essential for intracellular pH regulation in CD8(+) T-cells upon CD3 stimulation, modulating CD8(+) T-cell responses (By similarity).
Subcellular location: Apical cell membrane {ECO:0000269|PubMed:22310983}; Multi-pass membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000269|PubMed:10600827, ECO:0000269|PubMed:8141271}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Solute carrier family 12 member 2
- Cystic fibrosis transmembrane conductance regulator
- Aquaporin-1
Sequence:
MSSAPRRPASGADSLHTPEPESLSPGTPGFPEQEEEDELRTLGVERFEEILQEAGSRGGEEPGRSYGEEDFEYHRQSSHHIHHPLSTHLPPDARRRKTPQGPGRKPRRRPGASPTGETPTIEEGEEDEDEVGEAEGFRAPPQQPSPASSPSAVQFFLQEDEGTDRKAERTSPSPPTQTPHQEAAPRASKGAQTGTLVEEMVAVASGTAGGDDGGAAGRPLTKAQPGHRSYNLQERRRIGSMTGVEQALLPRVPTDESEAQTLATADLDLMKSHRFEDVPGVRRHLVRKNAKGSTQAAREGREPGPTPRARPRAPHKPHEVFVELNELQLDKNQEPQWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTLAHGAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDRANVLRALLLKHSHPSDEKEFSFPRNISAGSLGSLLGHHHAQGTESDPHVTEPLIGGVPETRLEVDRERELPPPAPPAGITRSKSKHELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLGPSSANMDYHEIGRSISTLMSDKQFHEAAYLADERDDLLTAINAFLDCSVVLPPSEVQGEELLRSVAHFQRQMLKKREEQGRLLPPGAGLEPKSAQDKALLQMVEVAGAAEDDPLRRTGRPFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEKTQDLIGVSELIMSTALQGVIFCLLGAQPLLVIGFSGPLLVFEEAFFSFCKSNQLEYLVGRVWIGFWLVLLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYETFYKLIKIFQEHPLHGCSVSNDSEADSSSNNMTWAATTLAPDNSSASGQERPRGQPNTALLSLVLMAGTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMVLVDYSIEDTYTQKLSVPSGFSVTAPDKRGWVINPLGEKTPFPVWMMVASLLPAVLVFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSMVIGDLLRQIPLAVLFGIFLYMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTMRMHLFTALQLLCLALLWAVMSTAASLAFPFILILTVPLRMVVLTRIFTEREMKCLDANEAEPVFDECEGVDEYNEMPMPV
Protein: Ras guanine nucleotide exchange factor R (RasGEF domain-containing protein R) (Q8SSQ0)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Promotes the exchange of Ras-bound GDP by GTP. May also play a role in the activation of rasG.
Interaction partners:
- Ras-like protein rasG
Sequence:
MKEEEIANLGPQEYFNYLEGINKKIIIELKTVANIDTAKDTDNLQNILIESSLALEHNIRNLLYFVDKCPISYDQIVHYHSHFKEVVKIFFQVCQDLIKAAQALILNSCDYLTTSNFAKCRGEAIKTIKNTMATCSNFEKLYYNPDLQLEDEVDLVHQQQQKEQEQQQKEQEQYEQEQLILKQLKEQELKKQQEQQQQQQQQQQQQQQQQQQQQQKHQEEKEKNDQKEKEEKLKKQLLAEQQKQKQEELERQQQQLQQQQQLLQQQQQLLQQQQQQQRSDPIIIPPITLKTSQSDLLSGGLSPKVNSPGSPNLGKFTESAERVANFDRGTANIILNMNKIKEISLSGDSEQAPEIVTAARIISENIAIISKELRYKTLGTNLSEHFVSVVQVARLAIKNKSDQFYQDQLELAIEKFNDTMRKIIYSVKSISKSSMNLRQFGVDESSLGRSPVVSPEKSISPSFTSSTSERILSHEIKNHNNNNNNYNNSSTNNLQTSFSTPSLSSNHSQQPNQQPLQSPLLINQLQSTSSSSSSSSSNLSNSLNSIQLPQATTTTTTATSPSTSTSTSTSTSPNSSSLSISDQDKQLKRKEKQHQIVIPKDVKDSVANQQQQQQQQQNGTTSPRNNESSVTAATTTTTSTTASITTNVNTIPNFPPNKQLPATPTTGTPSTSTPTPQTPTSTSQNDKQNENNNKENFVDKQKTLGKLFSKFVHKKRTPLPGFDSSNSSSPSNNSNTTNSSSHSSTNSSPMETSPGVESPKITKSPSQNNILVDSLDIGSDNQQQQQDKLTTTTSTTTITINNNNNNNNNNNNNNNNNNNNIQQQQQQQQQIPTTPNKLSNSIAMNSSNRLMTPKKERSFTIGLVSGKHSCVVVETPKSKKLFQHESAKQILSIISMNFPSFEKEFQMQNSEVISNIIEQIGNVIKNYHDEVSESSSSSSSSTTSPNNINTPSDCSPILNSENSKDSHNLSSINNSSYDPVSPALRKMYENGSYDSKEHSRSSIQSKITRKLGTIRKKGPSPFNMLLNSSTGSLSSLYLDQLNGGNGDSSSSSSSSYNLVGGSGISGYDNQNEIDASEHLVSTSSLFTEEAIELVSKCFEASIIVNHSGGTSSEIKALFSSTLDHLESMLQSSVNFGKIDPSSFCMTFLKNIRQHIPTMKSKGGKCDPTLVTAATKLFRHTILSNLDKSIHSLCHSVRVLAIQMTIIVISISAKPWDISSQLQLFASAKSFIDSLVSLLDAVENKIYISTNTNIQDDVEVPTIDDTEDTNIWEEADSPLTFGWISDEGSKTGRYVPKAGTLNKLISALTQDNKHDISRYTKTFLLTYQSFTNPWKLMEKLIQRYNVPLDEKPDVRATTQLRVVSFMQTWIERNFNDFDDQLIGQLKEFRTRLLMDNNNDLAVILGGLIKKKEAERSLSKERSTNHLTFPELMIPDGQKSPTALFLLLNESEIARQLTLIDFNIFSKIQPTELLDQSWNKDSLKFKSPNVIEMINRANKFSFWVSSQILWQEDIEERVKVFEKFILISKYLREMNNFNTLLAIFTGLNTAPILRLKKTFALLSPNSLSIYNSLEKLMNSSGSYKNYRSVSKNPPLLPYLPVILSDLTFMEDGNPDKINNLINFQKRELICRVISEVQQCQQQTKYEFPVVEPIHTLLTELPSSTPSELYQLSLIREPRETNQSNANSSISSGSNFLSNSSNHNIGNNNGFDTLKKYYKSSNNN
Protein: Ras-related protein Rab-32 (EC 3.6.5.2) (Q9CZE3)
Organism: Mus musculus (Mouse)
Function: Acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and Mycobacterium (By similarity). Plays an important role in the control of melanin production and melanosome biogenesis (By similarity). In concert with RAB38, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes.
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q13637}. Mitochondrion outer membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Cytoplasmic vesicle, phagosome {ECO:0000250|UniProtKB:Q13637}. Cytoplasmic vesicle, phagosome membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Melanosome {ECO:0000269|PubMed:26620560}. Melanosome membrane {ECO:0000250|UniProtKB:Q13637}. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis. The BLOC-3 complex, a heterodimer of HPS1 and HPS4 promotes its membrane localization. {ECO:0000250|UniProtKB:Q13637}.
Interaction partners:
- Ankyrin repeat domain-containing protein 27
- Geranylgeranyl transferase type-2 subunit alpha
- BLOC-3 complex member HPS4
- BLOC-3 complex member HPS1
- Prohibitin-2
- AP-3 complex subunit beta-1
Sequence:
MAGEGLGQQGASATAAPETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDIAGQERFGNMTRVYYKEALGAFVVFDISRSSTFDAVLKWKNDLDSKVHLPNGSPIPAVLLANKCDQKKDNSQSPSQMDQFCKDHGFTGWFETSAKDNINIDEATRFLVENMLANQQSFPSEEIDLDRIKLVEEPPTTKPRSQCC
Protein: Zyxin (D4A7U1)
Organism: Rattus norvegicus (Rat)
Subcellular location: Cell junction, focal adhesion {ECO:0000256|ARBA:ARBA00004246}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- Vasodilator-stimulated phosphoprotein
- Talin 1
- Vinculin
- Talin 2
- Paxillin
- Alpha-actinin-4
- Alpha-actinin-1
- Actin, cytoplasmic 2
- Actin, cytoplasmic 1
- Breast cancer anti-estrogen resistance protein 1
Sequence:
MRREAAGGPLQSLRPRAGPGPLPGGVSCPALPPRPLPAPSPGRSLYGLGAALSPPPPSLPLRVVPPRLARSCSGPGRRVRGLGAEAVIRDAALTLLPAQPGLTMAAPRPPPAISVSVSAPAFYAPQKKFAPVVAPKPKVNPFRPGDSESPVAAGAQRAQMGRVGEIPPPPPEDFPLPPPPVIGEGDDSEGALGGAFPPPPPPLIEEPFPPAPLEEDIFPSPPPPLEEEGGPEAPTQLPPQPREKVSSIDLEIDSLSSLLDDMTKNDPFKARVSSGYVPPPVATPFVPKPSTKPAPVGTAPLPPWKAPSSSQPPPQPQAKPQVQLHAQPQAKPHVQPQSVSSANTQPRGPLSQAPTPAPKFAPVAPKFTPVASKFSPGAPSGPGPQPSQKSVPLEAPSSVGTGSPQPPSFTYAQQKEKPLVQEKQHPLPPPAQNQNQVRSPGGPGPLTLKEVEELEQLTQQLMQDMEHPQRQSVAVNESCGKCSQPLARAQPAVRALGQLFHITCFTCHQCQQQLQGQQFYSLEGAPYCEGCYTDTLEKCNTCGQPITDRMLRATGKAYHPHCFTCVVCACPLEGTSFIVDQANQPHCVPDYHKQYAPRCSVCSEPIMPEPGRDETVRVVALDKNFHMKCYKCEDCGKALSIEADDNGCFPLDGHVLCRKCHSARAQT
Protein: Small ribosomal subunit protein uS2c (30S ribosomal protein S2, chloroplastic) (P0C481)
Organism: Oryza sativa subsp. indica (Rice)
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Small ribosomal subunit protein mS29
- S5 DRBM domain-containing protein
- Small ribosomal subunit protein mS35 mitochondrial conserved domain-containing protein
- Uncharacterized protein
- Small ribosomal subunit protein uS12cz/uS12cy
- Small ribosomal subunit protein uS14c
- Uncharacterized protein
- Small ribosomal subunit protein uS9c
- Small ribosomal subunit protein uS7cz/uS7cy
- Small ribosomal subunit protein uS7c
Sequence:
MTRRYWNINLKEMIEAGVHFGHGIKKWNPKMAPYISAKRKGTHITNLARTTRFLSEACDLVFDAASQGKSFLIVGTKKRAADLVASAAIRARCHYVNKKWFSGMLTNWSITKTRLSQFRDLRAEEKMEKFHHLPKRDVAILKRKLSTLQRYLGGIKYMTRLPDIVIVLDQQKEYIALRECAILGIPTISLADTNCDPDLANISIPANDDTMTSIRLILNKLVFAICEGRSLYIRNH
Protein: H-2 class II histocompatibility antigen, A beta chain (P14483)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- H-2 class II histocompatibility antigen, A-B alpha chain
- H-2 class II histocompatibility antigen gamma chain
- H-2 class II histocompatibility antigen, E-B beta chain
- T-cell surface glycoprotein CD4
- Class II histocompatibility antigen, M beta 1 chain
- Class II histocompatibility antigen, M alpha chain
- H2-O alpha
- H2-M beta 2
- Histocompatibility 2, M region locus 3
- T-cell surface glycoprotein CD3 zeta chain
Sequence:
MALQIPSLLLSAAVVVLMVLSSPGTEGGDSERHFVYQFMGECYFTNGTQRIRYVTRYIYNREEYVRYDSDVGEHRAVTELGRPDAEYWNSQPEILERTRAELDTVCRHNYEGPETHTSLRRLEQPNVVISLSRTEALNHHNTLVCSVTDFYPAKIKVRWFRNGQEETVGVSSTQLIRNGDWTFQVLVMLEMTPRRGEVYTCHVEHPSLKSPITVEWRAQSESAWSKMLSGIGGCVLGVIFLGLGLFIRHRSQKGPRGPPPAGLLQ
Protein: ATP synthase subunit b' (ATP synthase F(0) sector subunit b') (ATPase subunit II) (F-type ATPase subunit b') (F-ATPase subunit b') (P15015)
Organism: Rhodospirillum rubrum
Function: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity).
Subcellular location: Cellular chromatophore membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Interaction partners:
Sequence:
MPQFDPSSFPSQIVWLVIALVAMYFVMSRLAIPRLAEVLEQRQRLINDDLKQAEALKAETEAAIAAYETALAEARARAHDEIRAVTEAAAKAAEARNAEVAKALNTRIKDGEARIVQARDEALTHVREVAGAVASDIVGKLAGLRVDDAALTAAVAAAIKE
Protein: Sister chromatid cohesion protein mis4 (SCC2 homolog) (Q09725)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Plays a structural role in chromatin. Chromatid cohesion molecule required for equal sister chromatid separation in anaphase. May form a stable link between chromatids in S phase that is split rather than removed in anaphase. Also required for spindle-kinetochore interaction in early mitosis and inhibit sister chromatid separation until the cleavage of Rad21 in anaphase.
Subcellular location: Nucleus. Chromosome. Note=Associates with chromosomes in a punctate fashion throughout the cell cycle. {ECO:0000305}.
Interaction partners:
- Structural maintenance of chromosomes protein 1
- Cohesin subunit rad21
- Structural maintenance of chromosomes protein 3
- MAU2 chromatid cohesion factor homolog
- Sister chromatid cohesion protein pds5
- Cohesin subunit psc3
- Meiotic recombination protein rec11
- Separin
- Wings apart-like protein homolog 1
- Structural maintenance of chromosomes protein 5
Sequence:
MLFEMTPETFKKVNSSNRIIKGLQYTPLASSIPLENGLQNVLYPSSKFQNEPLQLNSEESSIMQRYVDMLNPGATFVNDSETFNFYKNALSAMITEPAMPAMRVNASPVLDQKVCNSDSLSELNDFTKSLIQPSMLMCEPKEKPDASSINTNRSSSDNGFLTPSSSPRSPSCSRVFNAVQLCSPKKSKDDITTPKKRLMEDTYSPRESPSKIQRLQDVLLKQLQDTRLLISQVIEAENSEDFSSNSLFIKREDDDGKHISSHAIEKLYMALTKLSRLGACDKLLEEGSIILVKQILEKELKELPVACYSIINLHDSLTQFPNLDFILKTTALVLFIIFLVPSFKKLQNEESILHLLNILHSIFEYTVPEAIDNIVQSKTSDARTSEIQHLSVLLQKVANVLNILSKVAHEIPLSEAVVIRIVYLFPKVSTLDNSFKTKLPNCNSSSFDFLKAPLFQTLQYLFRLYPYQRDFIIEESLTNFSHLPTARSVSRTYRLSNGKSIQYYSTLFVRLIQSCSIQNLFDSEIVQSESKSTEALHSGNLTEHLKTVESILSKSRHEEYRIANHIVAYLLSRSLKQNKTESDNSFAILTKILLEDLLNMLSLPEWCGTETIIRQFAMNLVMTVTNDKQAVSSKNAALDLISLIVNKVLALFDLSLFEKHNIPAPTNFNDIISFIPSITRLNELSQVSFNHFYFLCKGDISLENILPYNYNKWFSFLLQLRKVCNDSEALKIIDNCIDKNMQKSQEGFQGPSPFKADENDEDIFIISLYHSSLFLNLKFFVSLIIGFLDSPQASLRTKCLRIINQMKTIPSILRTHPEVLAQIISKSNDQSAIVRDTVLDLLGTYIMAYRETIPQIYGCIISGISDPSTIVRKRAIKQLCEVYEATEDLNIRVDIASKLLTRSNDEEETISELSLEVLEKLWFSPASNELDCQKGYEQLTFLEKQKLRVQYFPILKLCAEPSTERHVLLVTSLKTMLTSKEEINLSTLHTQIRLLLSCLFNQLIEVVTEDQVDESTKGILYEIMSTLFVFSRAFPFLFDLSYLHLLKPYLRSASTIEEQRFLYYVVAIFRQVLPFQKEISESFLRSLESVLLQRLTKAGTATLMEIVPCLCSLFTRLNDYERLKKIVVSCLKSLEEARHSENNFQKMVRLIDLIGLFSRYGDLNRINDDWKHSLDFISPECDDAYVILLGYFQKLLKDAKGQLRIHIIDNMSRICLRETSLFISPLMLSTLDMIIAENNVNEVSVLFKSFLELLAADEDLIFEADQKLSLKGKQNVQSNKSVDRDMLKGTKDKQWIEGVSASLMQHFLPCILDSCFSKNLRYSMLGIEILKCIIHQGLVNPRMCFSTIIALESNAIKETREVAILLHTELHRRHESLIDGLYAQSADLIFSLQKTEEYQTFKLGEFSPFQSAYTIVSADKSSKSRKKLIMQILKPLKLDGIDLPSFTEEKVSFVSFCCVCLAGIPYVSIEEPLMIISTVDSVLATIGPTITGWMKKLDHERFKILAGINLCNLIYLKRYIKYAFSISDSSRPIREKKPLTLLNRGYVDLITSDAKPDIVSKLVIKLFEEENILSGEDQVEGEQLTVV
Protein: Oligopeptide/dipeptide uptake family ABC transporter, permease protein (Q5LMM7)
Organism: Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU363032}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU363032}.
Interaction partners:
- Oligopeptide/dipeptide uptake family ABC transporter, permease protein
- Oligopeptide/dipeptide uptake family ABC transporter, periplasmic substrate-binding protein
- Oligopeptide/dipeptide uptake family ABC transporter, ATP-binding protein
- ABC transporter, periplasmic substrate-binding protein
Sequence:
MGAYILRRLLLVIPTLLGIMLVNFVLVQFVPGGPVDQAIAQLQGGGDVFESFAGQGNDAQLNSQTNAVNDSYIGARGLPPEFIKELEELYGLDKPAHERFLMMLWNYMTLDFGESYFRKIDVVDLVLEKMPVSITLGLWSTLIAYAISIPLGIRKAVRDGSRFDTWTSGLIIAAYAIPGFLFAILLLVLFAGGSYWQIFPLRGLTSDNFSDLSLLGKVLDYFWHIALPLTAYTIGAFTTLTLLTKNSFLDEIKKQYVITARAKGLSESRVLYGHVFRNAMLIVISGFPGVFLSVFLGGSLIIETIFSLDGLGRLGFEATVARDYPVMFGTLFVFGLIGLLVGILSDLTYVLVDPRIDFERREG
Protein: Cysteine desulfurase NifS (EC 2.8.1.7) (Nitrogenase metalloclusters biosynthesis protein NifS) (P05341)
Organism: Azotobacter vinelandii
Function: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.
Interaction partners:
Sequence:
MADVYLDNNATTRVDDEIVQAMLPFFTEQFGNPSSLHSFGNQVGMALKKARQSVQKLLGAEHDSEILFTSCGTESDSTAILSALKAQPERKTVITTVVEHPAVLSLCDYLASEGYTVHKLPVDKKGRLDLEHYASLLTDDVAVVSVMWANNETGTLFPIEEMARLADDAGIMFHTDAVQAVGKVPIDLKNSSIHMLSLCGHKLHAPKGVGVLYLRRGTRFRPLLRGGHQERGRRAGTENAASIIGLGVAAERALQFMEHENTEVNALRDKLEAGILAVVPHAFVTGDPDNRLPNTANIAFEYIEGEAILLLLNKVGIAASSGSACTSGSLEPSHVMRAMDIPYTAAHGTVRFSLSRYTTEEEIDRVIREVPPIVAQLRNVSPYWSGNGPVEDPGKAFAPVYG
Protein: PRA1 family protein 3 (ADP-ribosylation factor-like protein 6-interacting protein 5) (ARL-6-interacting protein 5) (Aip-5) (Addicsin) (GTRAP3-18) (Glutamate transporter EAAC1-interacting protein) (Prenylated Rab acceptor protein 2) (Protein JWa) (Q8R5J9)
Organism: Mus musculus (Mouse)
Function: Regulates intracellular concentrations of taurine and glutamate (By similarity). Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate in a PKC activity-dependent manner. Plays a role in the retention of SLC1A1/EAAC1 in the endoplasmic reticulum (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:12438930}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:Q9ES40}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm {ECO:0000269|PubMed:12438930}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12438930}. Note=Also exists as a soluble form in the cytoplasm. Associated with microtubules. {ECO:0000269|PubMed:12438930}.
Interaction partners:
- Excitatory amino acid transporter 3
Sequence:
MDVNLAPLRAWDDFFPGSDRFARPDFRDISKWNNRVVSNLLYYQTNYLVVAAMMISVVGFLSPFNMILGGVIVVLVFMGFVWAAHNKDILRRMKKQYPTAFVMVVMLASYFLISMFGGVMVFVFGITLPLLLMFIHASLRLRNLKNKLENKMEGIGLKKTPMGIILDALEQQEDNINKFADYISKARE
Protein: Heparin-binding fibroblast growth factor receptor 2 (Q63237)
Organism: Rattus norvegicus (Rat)
Interaction partners:
Sequence:
MLPTNISVQMGLTSTWRYGTGPGIGTVTMVSWGRFICLVLVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEACVVAPGESLELRCMLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACAAARTVDSETLYFMVNVTDAISSGDDEDDTDSSEDFVSENRSNQRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCLVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPVREKEITASPDYLEIAIYSIGVFLIACMVVTVIFCRMKTTTKKPDFSSQPAVHKL
Protein: Defective proboscis extension response 14, isoform A (Defective proboscis extension response 14, isoform B) (GH19181p) (Q9W3N2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Dpr-interacting protein epsilon
Sequence:
MRSRLFWILAIIYSSLHHIGSGSTSTTLKRPRAGDPFDTFPKNFWQEFSSPFTDTPEDEELEVTETTTHEPFPFFADPYTTLNISTQLSSSVYLHCRVNDLQGKTVSWMRRRGDDLTLITFGQHTYSGDSRYSLEFEEPNDWKLLIQFANERDEGPYECQVSSHPPLVLLVYLTIIVPHVEILDERGSATPEKYYKAGSTIELQCVISKIPHPSSYITWRHGPRLLNYDTSRGGISVKTDMLPGRALSRLYIANANRQDTGNYTCMLGNEITETVVVHVLNGEEPAAMQHANGSRQKANASTMVVLFLVYVCISGSISVAGMNRGLGLGQVWGWGWELRR
Protein: Muscleblind like splicing regulator 1 (C9JCX1)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MAMLAQQMQLANAMMPGAPLQPVPMFSVAPSLATNASAAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKI