Protein: Calpain-type cysteine protease DEK1 (EC 3.4.22.-) (Phytocalpain DEK1) (Protein DEFECTIVE KERNEL 1) (ZmDEK1) (Q8RVL1)
Organism: Zea mays (Maize)
Function: Essential protease involved in epiderm development. Required for aleurone cell development in the endosperm probably by maintaining and restricting the aleurone and embryonic epidermal L1 cell-layer fates as well as meristems organization. Involved in the maintenance of adaxial/abaxial axis information in developing leaves, probably by regulating cell proliferation and expansion. Does not need calcium ions to be active.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000269|PubMed:17933905}; Multi-pass membrane protein {ECO:0000269|PubMed:17933905}. Endosome membrane {ECO:0000269|PubMed:17933905}; Multi-pass membrane protein {ECO:0000269|PubMed:17933905}.
Interaction partners:
- Peflin
- Putative calcium-binding protein CML50
- Putative calcium-binding protein CML48
- Putative receptor protein kinase CRINKLY4
- Superal1
- Uncharacterized protein
- Empty pericarp4
- Associate of C-myc
- Guanylate kinase 1
- guanylate kinase
Sequence:
MEGEGHHGVVLACSICGFLFAVLSPFSFWVLWAVNWRPWRLYSWIYARKWPTYVQGPQLSTLCSLLTLCAWLVVISPIAVLLVWGSVLIALMERNIIGLAVIMAGVALLLSFYSIMLWWRTQWQSSEAVAYLLLLAVCLLCAYDFCAIYVTAGASASELNSPSGFFFGVSVISLAINMLFICKILFNVSGFDVDEYVRRSYKFAYSDCVEVAPVSCSPEPPDPSELYMTKSSRVKHLGLLYISSLLVLVGYSILYGLTSKEARWLGALTSVAVVILDWNLGLCSFRFELLKSRMIVLFVAGTSRAFLVSFGVHYWYLGHCISYAFVASVLLSAAVSSWLSISNPSVARIDALRSTVIKLREGFRRKGQNSSSNSSEGCGSSVKRSSGSVEAGQNGNAMDSMYRSNSQSDGVNWSSIPFDRSNSCQEGRSSDKNIDSARASLAHRSNSCLSAVQDSETAVVSVDRHGDPITSLVCSSSGLESHGCEPSGSATTSGNQQLLDLNLAAIFQDRLNDPRISSMLKKNGGLGDVELANLLQDKGLDPNFSYMLKDKVMDPRILALLQRSSLDADREHQDDVDVTATDSDRLDTTIANQISLSEELRRSGLEKWLNISRLIFHHLAGSPIRAFIVFTVMFIIETATVAIYRPETIKVINATHEQFEFGFSILLLSPVVCSIMAFIWSLRAEEMLMTSKPQKYGFIAWLLSTCVGLFLSFLSKSSVILGLSLTVPLMVACLSFAVPIWIRNGYSFWIPGREFANRENVSQAPGEKERALFVITIAVFTASIIGLGAIVSAKPLDALGYKGWDADKNSSYSPYATSMYLGWALSSTIAVITTGLIPIVAWFATYRFSPSSAICVGLFATVLVSFCGASYWGVVNSREDGVPLKADFLAALLPLLCIPAFFSLFTGLYKWKDDDWKISRGVYLFVGMGMLLLFGAVAAVIVTIRPWTVGVACLVAILFLVFVIGVIHYWTSNNFYLTRTQMLLVCSIAFLLALAAFLMGLFHGKPFVGASIGYFSFIFLLTGRALTVLLSPPIVVYSPRVLPVYVYDAHADSAKNVSYAFLILYGIALATEVWGVIASLIMNPPFVGAGVSATTLVIAFSFAVSRPCLTLKMMEDAVHFLSKDTVVQAMSRSANKTRNAISGTYSAPQRSASSAALLVGDPALTLDRAGNFVLPRADVMKLRDRLRNEEIAAGSFLCGVKDCLLICPQSLSNIDYRRNMCAHARILALEEAIDTEWVYMWDKFGGYLLLLLGLTAKAEQIQDEVRLRLFLDSIGLSDLSAKEIKKWMPEDRRQFELIQESYIREKEMEEEALMQRREEEGKGRERRRALLEREERKWKELEISLLSSIPNTGSRDAAAMAAAVRAVGGDSALEDSFARDRVSSIANHIRKAQLARRAEQTGIPGTICILDDEPRSTGRHCGELDLCLCQSQKVTLSIAVMVQPVSGPVCLFGSEFQKVCWEILVAGSEQGMEAGQVGLRLVTKGERMTTVAKEWNIGASSIADGRWHLVTVTLDADLGEATSFIDGVYDGYQNGLPLPTDNGIWEPGTDIWVGARPPMDLDAFGRSDSEGSDSKMQIMDAFLWGRCLSEDEVTVLHTAMSPAEYGFFDLAPGDAWHGSYSARVDDWESEEAYELYDQGDVEWDGQYSSGRKRPVHDAVAIDLDSFARRPRKPRFETRDEVNQRMLSVERAVRDALIAKGERNFTDQEFPPEDRSLFVDPMNPPLKLQVVSEWMRPSDIAKDISISCQPCLFSGSVNSSDVCQGRLGDCWFLSAVAVLTEMSRISEVIITPEYNDEGIYTVRFCIQGEWVAVVVDDWIPCESPGKPAFATSRKQNELWVSILEKAYAKLHGSYEALEGGLVQDALVDLTGGAGEEIDMRSPQAQLDLASGRLWSQLLHFKQEGFLLGAGSPSGSDAHISSSGIVQGHAYSILQVREVDGHKLIQIRNPWANEVEWNGPWSDSSPEWTERMKHKLMHVPQSKNGVFWMSWQDFQIHFRSIYVCRVYPPEMRYSVHGQWRGYNAGGCQDYDSWHQNPQYRLRVTGRDALYPVHVFITLTQGVGFSRKTNGFRNYQSSHDSSMFYIGMRILKTQGCRAAYNIYMHESAGGTDYVNSREISCELVLDPYPKGYTIVPTTIHPGEEAPFVLSVFSKASIRLEAV