wanglab/gogpt-training-data huggingface dataset:
Protein: ADP-ribosylation factor, putative (Q38B80)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Conserved oligomeric Golgi complex subunit 8
- Small GTP-binding protein RAB6, putative
- ADP-ribosylation factor-like protein, putative
- Conserved oligomeric Golgi complex subunit 6
Sequence:
MSSSEHDSRVAYCKEHNVHHLFELMASRLLVERPENPFEYLRELLVTVENSKKQTAHDPTMLPSSPLGAKDKLTKITIGTFGIENAGKTTIISALGGNIEKNPMPTVGFTPTRFQTDRCDLCIFDLGGGANFRGIWVHYFHDCHGFMFVIDSAADDAVVEESLNALRTVAQHKHVRGKPVLVLANKKDLKSSRGVEIVSEGLLEELFGDVSLYHLVPSCGIEEDPELEKGVDWLLTKIQKEYTHIDKLVESQTLEVKMEAEQKRKKLLEE
Protein: SD16013p (Q8IG94)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
TSAKMWQFENKNATKMKTSQNEMPDKDKSFRRHSLSPRSLSAIFFHSTGLHLDDGVAQWLSINVKEDITNLLNEAGKYMRRIRDRRLQLSHIQHAVRMHDDLCYDIFFRLVHCDDCKMPPSQKVLKTVSEAVTAEKKDELLVSYPESVQESVPEPVPETSLEPPPMHTGWLKVEQVLLKPSKRYPLSMEQQNFFEFVTEACVGDLESRRVLALKAISTDPSLEELLPRLTKFIADAVAINVAQQNLPLLLYLMRMVRALLGNQRFSLLQYLHLLLPAVLSCLLAKQVCASPNSEDHWALREYSGNIMAHIVRQFDAADNGILPRVIGVYNKALLKKPLTTVFGAVIGLGKMGNHAVRACILPQLKYLSEHIDSHMAASNDSPSSSVDRQAVKYIRHRLMKMCSPVLMGIHQPPDLPEEFMERYGSLGTLMSDGVTVMRTKKQAVAAAKAEAELKLKNMATEHLNSRGKGSRSVGSNDLVSGTQLPKNGIRPTSQAPKSVYSISVNGQTVKISTPNLCNTMLQHQKKDLFSKPSDFVVPQLVVNQFKNGLIPSNSQRSSSPARNVIH
Protein: Splicing factor U2AF 26 kDa subunit (U2 auxiliary factor 26) (U2 small nuclear RNA auxiliary factor 1-like protein 4) (U2AF1-like 4) (Q8BGJ9)
Organism: Mus musculus (Mouse)
Function: RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. It can functionally substitute for U2AF1 in constitutive splicing and enhancer-dependent splicing. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site. Shows a preference for AGC or AGA. Alternative splicing of U2AF1L4 may play a role in connecting the circadian rhythm to changing external cues: may provide a circadian buffering system in central and periphery clocks that allows synchronized adaption to clock-resetting stimuli in order to prevent potentially pathogenic desynchronization.
Subcellular location: [Isoform 1]: Nucleus {ECO:0000269|PubMed:11739736, ECO:0000269|PubMed:18460468}. Nucleus speckle {ECO:0000269|PubMed:11739736}. Cytoplasm {ECO:0000269|PubMed:16819553, ECO:0000269|PubMed:18460468, ECO:0000269|PubMed:24837677}. Note=Interaction with C1QBP is required for the nuclear translocation. Displays active nucleo-cytoplasmic shuttling. {ECO:0000269|PubMed:18460468}.; SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm {ECO:0000269|PubMed:18460468, ECO:0000269|PubMed:24837677}.; SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:18460468}.
Interaction partners:
- Splicing factor U2AF 65 kDa subunit
- Splicing factor U2AF 35 kDa subunit
- Splicing factor 1
- Serine/arginine-rich splicing factor 2
- Serine/arginine-rich splicing factor 5
- Serine/arginine-rich splicing factor 1
- Serine/arginine-rich splicing factor 3
Sequence:
MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIVLLNLYRNPQNTAQTADGSHCHVSDVEVQEHYDNFFEEVFTELQEKYGEIEEMNVCDNLGDHLVGNVYVKFRREEDAERAVAELNNRWFNGQAVHAELSPVTDFRESCCRQYEMGECTRGGFCNFMHLRPISRNLRRQLYGRGPRHRSPPRSHTGHRPRERNRRRSPDHRHGRF
Protein: Microtubule-associated protein 1 light chain 3 beta, isoform CRA_c (cDNA FLJ77661, highly similar to Homo sapiens microtubule-associated protein 1 light chain 3 beta(MAP1LC3B), mRNA) (Q658J6)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Interaction partners:
Sequence:
MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFGMKLSV
Protein: White collar 1 (Q5EGQ2)
Organism: Cryptococcus neoformans var. neoformans
Interaction partners:
Sequence:
SVDYTYSIPPEKPLQLDGKGAAIAGLSTAVLDIMGSRTKALAAGTEEGARMEWFKMILDNTDDFIHALSLKGFFQYASSSIRRSLGYEPEDLLNKNISEFAHPSDIVPVIRALKDSTQTIGEEQQPKPVHFTFRIRTKNFGYVWVESMGRLVVEAGKGRKAVILSGRVRNMPTLSWGKVAEHGGLAKTEFWAKISFQGLLLNLTFGVDKVLGYQAEEILGRNLFSLLPGGQNTPPSGEHLINNYASAPDIAPVAKAIYQTIHDSTHRGALSIRQKMVHRSGQPVDVILVFYAPGQAKDKQSPISYSNNDESASVNFIGTPNGASTYPVKITDIFVQVKLLSSSPSHQRSVQPPSIASLTQARPLVHLPNDNIFEELETGRDSSWQYELHQMKMTNRRLRDSIAALKEKKAGKAKKRKYNIVDESPENQSEIIDTSLSSQIGGIGF
Protein: Leucine-rich repeat protein (LRRP), putative (Q386A8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MICRFPVDISKVWGNKRFQGQLYLNMTSAGRPQVTLDENYTGEDVGNLSRSATLECLTAKKCGKLKSVKFEKAKNLVCLHAESCGKLKVIDVSSCCKLESLTVTKCKNLKEVHGLPDACELLALNLSGCGKLEQVEGLCATNIKVKKLNLSGCKLLEPLGVLGCCKNVTELDLSGCKNINQSSMEIACKELNGLETLKLSGVPTVSDNWVWSLGVSNRSNANLLYLDLSRCLDIENAGPLSMIRSLKELSLDGCTSISKGLEAVCGLPNLKKLLLSKTKVTDECLENIKGNRNLVVLGCSGCLGISSISCIGEVKSLEELSLEGCTNIKKGLDILPRLPKLQKLWICGLNVPETIKQKLKTQGVKTNPLR
Protein: ERC protein 2 (CAZ-associated structural protein 1) (CAST1) (Cast) (Cytomatrix protein p110) (Q8K3M6)
Organism: Rattus norvegicus (Rat)
Function: Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ.
Subcellular location: Cytoplasm. Synapse. Presynaptic active zone {ECO:0000305|PubMed:12163476}. Cytoplasm, cytoskeleton. Note=Localized to the active zone of presynaptic density. Colocalizes with RIMS1 and BSN in early stages of synapse formation.
Interaction partners:
- Protein bassoon
- Protein unc-13 homolog B
- Regulating synaptic membrane exocytosis protein 2
- Regulating synaptic membrane exocytosis protein 1
Sequence:
MYGSARTISNPEGSPSRSPRLPRSPRLGHRRTSSGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEGVASTTYPKGTMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLGGSSHHHHHQVPSMLRQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKNDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREFSMVDNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRMERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQTQNRMKLMADNYDDDHHHYHHHHHHHHHRSPGRSQHSNHRPSPDQDDEEGIWA
Protein: Gag polyprotein [Cleaved into: Matrix protein p17 (MA)] (Q72497)
Organism: Human immunodeficiency virus type 1 (HIV-1)
Subcellular location: [Matrix protein p17]: Virion membrane {ECO:0000256|RuleBase:RU004487}; Lipid-anchor {ECO:0000256|RuleBase:RU004487}. Host nucleus {ECO:0000256|RuleBase:RU004487}. Host cytoplasm {ECO:0000256|RuleBase:RU004487}.; SUBCELLULAR LOCATION: Host cell membrane {ECO:0000256|ARBA:ARBA00004425}; Lipid-anchor {ECO:0000256|ARBA:ARBA00004425}. Virion {ECO:0000256|RuleBase:RU004487}. Host cytoplasm {ECO:0000256|RuleBase:RU004487}. Host nucleus {ECO:0000256|RuleBase:RU004487}.
Interaction partners:
Sequence:
MGARASVLSGGELDKWEKIRLRPGGKKQYKLKHIVWASRELERFAVNPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTIAVLYCVHQRIDVKDTKEALDKIEEEQNKSKKKAQQAAADTGNNSQVSQNYPIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPGATLEEMMTACQGVGGPGHKARVLAEAMSQVTNPATIMIQKGNFRNQRKTVKCFNCGKEGHIAKNCRAPRKKGCWKCGKEGHQMKDCTERQANFLGKIWPSHKGRPGNFLQSRPEPTAPPEESFRFGEETTTPSQRQEPIDKELYPLASLRSLFGSDPSSQ
Protein: Calcium-dependent protein kinase 7 (OsCDPK7) (OsCPK7) (EC 2.7.11.1) (Calcium-dependent protein kinase OsCDPK1) (Calcium-dependent protein kinase OsCDPK13) (Calcium-dependent protein kinase isoform 11) (OsCPKII) (P53684)
Organism: Oryza sativa subsp. japonica (Rice)
Function: May play a role in signal transduction pathways that involve calcium as a second messenger (By similarity). May be a signaling component in the response to gibberellin and cold stress.
Subcellular location: Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Cytoplasm, cytosol {ECO:0000269|PubMed:15604699}.
Interaction partners:
- Respiratory burst oxidase homolog protein B
- Os12g0541300 protein
- Os09g0438000 protein.
- Os11g0537400 protein
- Os08g0453700 protein
- Serine/threonine-protein phosphatase BSL1 homolog
Sequence:
MGNQCQNGTLGSDYHNRFPREHAVGYVQGDSYLDLKKFDDTWPEVNNFKPTAASILRRGLDPTSINVLGRKTADLREHYIIGRKLGQGQFGTTYLCTEINTGCEYACKTIPKRKLITKEDVEDVRREIQIMHHLSGHKNVVAIKDVYEDGQAVHIVMELCAGGELFDRIQEKGHYSERKAAELIRIIVSIVAMCHSLGVMHRDLKPENFLLLDKDDDLSIKAIDFGLSVFFKPGQVFTELVGSPYYVAPEVLHKRYGPESDVWSAGVILYVLLSGVPPFWAETQQGIFDAVLKGHIDFQSDPWPKISDSAKDLIRKMLSHCPSERLKAHEVLRHPWICENGVATDQALDPSVISRLKQFSAMNKLKKLALRVIAERLSEEEIAGLREMFKAVDTKNRGVITFGELREGLRRFGAEFKDTEIGDIMEAAHNDNNVTIHYEEFIAATLPLNKIEREEHLLAAFTYFDKDGSGYITVDKLQRACGEHNMEDSLLEEIISEVDQNNDGQIDYAEFVAMMQGSNVGLGWQTMESSLNVALRDAPQVH
Protein: MotC (G3XD73)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane {ECO:0000256|RuleBase:RU004057}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU004057}.
Interaction partners:
- MotD
- Chemotaxis protein MotB
- Flagellar motor switch protein FliG
- Flagellar motor switch protein FliM
- Flagellar motor switch protein FliN
- Flagellar basal-body rod protein FlgC
- Flagellar basal-body rod protein FlgG
- Flagellar biosynthesis protein FlhA
- Flagellar biosynthetic protein FliQ
- Flagellar biosynthetic protein FliP
Sequence:
MDVLSLVGIILAFVAIVGGNFLEGGHAGALLNGPAALIVIGGTLAAALLQTPVNVLKRGLGMLGWVFFPPREDLSGGIDRIVSWSMTARKEGLLGLESIADAEPDPYARKGLQLLVDGAEPEVIRSILEVDLFTQESRDLQAAKVFESMGGYAPTIGIIGAVMGLIHVMGNLANPAQLGSGIAVAFVATIYGVGFANLLLLPIGNKLKTLVLRQSRYREMLLEGLLSIAEGENPRSIELKLQGFMD
Protein: Zinc finger CCCH domain-containing protein 14 (Q8BJ05)
Organism: Mus musculus (Mouse)
Function: Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
Subcellular location: Nucleus speckle {ECO:0000269|PubMed:19303045, ECO:0000269|PubMed:21734151}. Note=Colocalizes with poly(A) RNA in nuclear speckles. {ECO:0000269|PubMed:21734151}.
Interaction partners:
- Nuclear cap-binding protein subunit 2
- DAZ-associated protein 1
- RNA-binding protein Musashi homolog 1
- RNA-binding protein Musashi homolog 2
- Transportin-2
- Transportin-1
Sequence:
MEIGTEISRKIRSAIKGKLQELGAYVDEELPDYIMVMVANKKSQDQMTEDLSLFLGNNTIRFTVWLHGVLDKLRSVTTEPSSLKSPDASIFDSHVPSNKSSFSRGDERRHEAAVPPLAVSSSRPEKRDSRVSTSSQEQKSTNVRHSYDDGASTRLMSTVKPLREPAPSEDVIDIKPEPDDLIDEDLNFVQENPLSQKKPTVTLTYGSSRPSIEIYRPPASRNADTGTHLNRLQLHPQQSSAHAAKQLDVQSSQVSEAGRLCEPPVLSSVEDTYSPFFRNNLDKMSIEDENFRKRKLPVVSSVVKVKRFSHDGEEEEEDEDYGTRIGSLSSSVSVPAKPERRPSLPPSKQANKNLILKAISEAQESVTKTTNYSAVPQKQTLPVAPRTRTSQEELLAEMVQGQNRAPRISPPVKEEEAKGDNTGKSQGTQQRQLLSRLQIDPVMVETMEMSQDYYDMESMVHADTRSFILKKPKLSEEIVVTPNQDSGMKTADALRVLSGHLMQTRDLVQPDKPASPKFIVTLDGVPSPPGYMSDQEEEMCFEGMKPVNQTSASNKGLRGLLHPQQLHLLSRQLEDPDGSFSNAEMTDLSVAQKPEKLLERCKYWPACKNGDECVYHHPISPCKAFPNCKFAEKCLFVHPNCKYDTKCTKADCPFTHMSRRASILTPKPVSSPAPSSNGQLCRYFPACKKMECPFYHPKHCRFNTQCTRPDCTFYHPTITVPPRHALKWIRPQSSE
Protein: Wtf element wtf11 (Q96WS1)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: May act in meiotic drive.
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Wtf element wtf14
- Meiotic drive suppressor wtf18
- Uncharacterized protein C17C9.11c
- Meiotic driver wtf4
- Intermediate cleaving peptidase 55
Sequence:
MNSNYVPLTSSVDVEEKMESENGVDLGNDIDLEKGLPLKYNSENESGLPSNSASSYLINPDPTMDLEAQTFNHNESTTSVGHDNSNSPPKCRKTCSSNKVYSNEVPLLFVFVISISIVCIFDLVIFGCLQYNMVSMDDLHVMQRLSWFCASLALLFILMRYYDFWTKACKDGIKHIFKKWKNTPLAFLQVLIFNIIGFFVRKGLKDSFGEQWGLKTSLFAHVSFATMSIFIFIFETLKPGSCSVDWIARILKAVVYFLEDSDEL
Protein: Uncharacterized protein encoded by LINC01547 (P58512)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MGWDCRRTTVENPSPIRNCVNQEWPEGSSPGLTEGNTGLVRDLRPAHQDRSGTREDPAGQETTAITNPSPSLAADLAGDALPGCLGAAAHQGPLLDRSSESTLGPQALELEHCHERGCCRGCASFSPFPAPRCPSERLGAHSSRWAIRGRSKINPPPWAPACLPGGFPACLPAPKSSTDSASSCFKGGREFSDPLDIPGAGAMG
Protein: Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) (NAD(+) synthase [glutamine-hydrolyzing]) (Q72BM5)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Interaction partners:
- NAD kinase
- Probable nicotinate-nucleotide adenylyltransferase
- MazG family protein
- 4-hydroxy-tetrahydrodipicolinate reductase
- Riboflavin biosynthesis protein
- Bifunctional chorismate mutase/prephenate dehydratase
- GMP synthase
- Riboflavin biosynthesis protein RibD
Sequence:
MKVALLQIDTVVGDIVGNAARIADAVREAASLGARLCVTPELALCGYPPRDLLLQDDFVPACRKALEALAQQLRDLPPVLVGAPVPNPSPVGNPIHNCAVLLREGKVTVATRKVLLPNYDVFDERRYFESGVGCGVVTIDGWRFGVTICEDVWNDKTFWQEHRHYENDPVADLMAGGADAILNLSASPFTLGKQAVRERMLSRVAFRYRVSVLYANQVGGNDDLVFAGKSIAFDATGTLIARGRSFAEDIVMVDVAQATGTITAEPTSDEEQVWKALVLGTRDYARKCGFDGAVLGLSGGIDSALVAAVAAEALGPDKVLGVLMPSPHSSEGSVTDALALASSLGIATCTIPIGDLMHGFEAALAQAFAGREADVTEENIQSRIRGNLLMALSNKQRRLLLTTGNKSELAVGYCTIYGDMAGGLAVIADLPKTLVYRVAHWLNERDTSHGHEGREARETIPSAILTKEPSAELRPGQRDSDSLPPYDVLDGILERLVELRRSAADIVAEGYDVETVRKVLRLVCNAEFKRRQAPPGLKVTDRAFGTGWRMPVAARVNLG
Protein: Interleukin family protein (Q6PVS0)
Organism: Ovis aries (Sheep)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU368043}.
Interaction partners:
Sequence:
MPQAENHGPDIKEHVNSLGEKLKTLRLRLRRCHRFLPCENKSKAV
Protein: Inner membrane protein YihN (P32135)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Uncharacterized protein YihM
- Uncharacterized membrane protein YhdT
- Probable cystine transporter YijE
Sequence:
MLTKKKWALFSLLTLCGGTIYKLPSLKDAFYIPMQEYFHLTNGQIGNAMSVNSFVTTVGFFLSIYFADKLPRRYTMSFSLIATGLLGVYLTTMPGYWGILFVWALFGVTCDMMNWPVLLKSVSRLGNSEQQGRLFGFFETGRGIVDTVVAFSALAVFTWFGSGLLGFKAGIWFYSLIVIAVGIIIFFVLNDKEEAPSVEVKKEDGASKNTSMTSVLKDKTIWLIAFNVFFVYAVYCGLTFFIPFLKNIYLLPVALVGAYGIINQYCLKMIGGPIGGMISDKILKSPSKYLCYTFIISTAALVLLIMLPHESMPVYLGMACTLGFGAIVFTQRAVFFAPIGEAKIAENKTGAAMALGSFIGYAPAMFCFSLYGYILDLNPGIIGYKIVFGIMACFAFSGAVVSVMLVKRISQRKKEMLAAEA
Protein: Uncharacterized protein (Q57ZI4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- SURP motif domain-containing protein
- Splicing factor 3A, putative
- Spliceosome-associated protein, putative
- Splicing factor 3B subunit 10
- Splicing factor 3B subunit 1, putative
- Uncharacterized protein
- PHD finger-like domain-containing protein 5A
- Probable eukaryotic initiation factor 4A
- RNA-binding protein, putative
- Sm protein G
Sequence:
MHDGSQQDASHGATAMNSGVVPDGQWRVDENIIIREILAMNTLAMQRCDTGALDESSSILTDAYMKLHNDTSTGESQGLDAVRATTLNNLGVVECHRGQHRQALSHFEAARQLEEAWSAASPSVALNSCAAYNALGMYDKATAAAMETINMLRRLFAQQEFQGSPTGEVASTPGGSCGAQPQSDGMNVASSDNAALWGAAWHNLAVAQINTAKSSTDLSEYTNAAALFQNAMRATQELLGYDHPMTKSVTETYRAVRNALRTHGVYKQHHTLFTAPLRPADPRDEADDMEQYFKQCGIKSRRRALEKYYRDLTITFCGAVTNGVKLTERLDPTPYPLAKDVSFRRSGQKDSLRMLRAIPTGSTIEKACHLYGNPHPLLFSLPPEYRASEVGTAKSIPKAASANSFAKVPMKPNALASSRRPQPKREQIFNEGQRRMQIQSNMPKQQQRQIGPPSTVVNYSRALQETPGAAPTIPQITPLSYKASIDEHWQPPVNQTPAPVNYNWSVQQQAPNTVPTAPLVYQQASVNQTPAPVNHNWSVQQQAPNTVPTAPLVYQQTPVNQGQAPLNHNWSAQQQAPNVVPTAPLVYQQASVNQTPAPVNHNWSVQQQAPNTVPTAPLVYQQAPVDQTPAPVNYNWSAQQQAPNTVPTAPLVYQQAPVSQGQAPAVASQPPLNQMPNVSQGESFDHQQGMSGRQEPLRQQEQQMLASCRRQAPADLGQGAAADHRSHQESVSNNTLVVGGQEEKKKKDHVQPVPAAPAAVPAGPAVGEASKPAAAVRGPLPPLKSPPGGRVIAKAETSDGVEGIVSAPRKASSGGQTATYDARRAYEQIKYILLADPPAEASRRKSKQDRSKKDSVPANVPQQECGPWTDNAAPAAGESPTEHKPHRLFDALWVSGGGPADQAPLRVVGKPSYFVSSVLDMRQGQAEFPEEVMQMVAENSRSSCSDVEERHSQTMGPAQHSCTEAGIPTHDQS
Protein: PICALM interacting mitotic regulator (I3L419)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MASRWQNMGTSVRRRSLQHQEQLEDSKELQPVVSHQETSVGALGSLCRQFQRRLPLRAVNLNLRAGPSWKRLETPEPGQQGLQAAARSAKSALGAVSQRIQESCQSGTKWLVETQVKARRRKRGAQKGSGSPTHSLSQKSTRLSGAAPAHSAADPWEKEHHRLSVRMGSHAHPLRRSRREAAFRSPYSSTEPLCSPSESDSDLEPVGAGIQHLQKLSQELDEAIMAEERTLRGSSVPCLPMELGKAT
Protein: Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2) (Q60838)
Organism: Mus musculus (Mouse)
Function: Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling.
Subcellular location: Cell membrane {ECO:0000269|PubMed:17199046, ECO:0000269|PubMed:20947020}; Peripheral membrane protein {ECO:0000269|PubMed:20947020}; Cytoplasmic side {ECO:0000269|PubMed:20947020}. Cytoplasm, cytosol {ECO:0000269|PubMed:21189423}. Cytoplasmic vesicle {ECO:0000269|PubMed:17199046, ECO:0000269|PubMed:21189423}. Nucleus {ECO:0000250|UniProtKB:O14641}. Note=Localizes at the cell membrane upon interaction with frizzled family members and promotes their internalization (PubMed:21189423). Localizes to cytoplasmic puncta. Interaction with FOXK1 and FOXK2 induces nuclear translocation (By similarity). {ECO:0000250|UniProtKB:O14641, ECO:0000269|PubMed:21189423}.
Interaction partners:
- Axin-1
- Vang-like protein 2
- Vang-like protein 1
- Low-density lipoprotein receptor-related protein 6
- Dapper homolog 1
- Segment polarity protein dishevelled homolog DVL-1
- Disheveled-associated activator of morphogenesis 1
- Axin-2
- Glycogen synthase kinase-3 beta
- Prickle-like protein 1
Sequence:
MAGSSAGGGGVGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSMDQDFGVVKEEISDDNARLPCFNGRVVSWLVSSDTPQPEVAPPAHESRTELVPPPPPLPPLPPERTSGIGDSRPPSFHPNVSSSHENLEPETETESVVSLRRDRPRRRDSSEHGAGGHRPGGPSRLERHLAGYESSSTLMTSELESTSLGDSDEDDTMSRFSSSTEQSSASRLLKRHRRRRKQRPPRMERTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPRNEPIQPIDPAAWVSHSAALTGAFPAYPGSSSMSTITSGSSLPDGCEGRGLSVHMDMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYASGLLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGASDQDTLAPLPGATPWPLLPTFSYQYPAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSDGGAGRTGRPEERAPESKSGSGSESELSSRGGSLRRGGEPGGTGDGGPPPSRGSTGAPPNLRALPGLHPYGAPSGMALPYNPMMVVMMPPPPPPVSTAVQPPGAPPVRDLGSVPPELTASRQSFHMAMGNPSEFFVDVM
Protein: Rhomboid-related protein 1 (RRP) (EC 3.4.21.105) (Rhomboid-like protein 1) (O75783)
Organism: Homo sapiens (Human)
Function: May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
- Rhomboid-related protein 4
Sequence:
MGRVEDGGTTEELEDWDPGTSALPAPGIKQGPREQTGTGPLSQKCWEPEPDAPSQPGPALWSRGRARTQALAGGSSLQQLDPENTGFIGADTFTGLVHSHELPLDPAKLDMLVALAQSNEQGQVCYQELVDLISSKRSSSFKRAIANGQRALPRDGPLDEPGLGVYKRFVRYVAYEILPCEVDRRWYFYRHRSCPPPVFMASVTLAQIIVFLCYGARLNKWVLQTYHPEYMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLRFSPPLPASGPQPSFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAVFWNVFAYDLLGAHIPPPP
Protein: Scaffold attachment factor B1 (SAF-B) (SAF-B1) (O88453)
Organism: Rattus norvegicus (Rat)
Function: Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing (By similarity). Functions as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription (By similarity). Thereby acts as a negative regulator of cell proliferation (By similarity). When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:9671816}.
Interaction partners:
- Tight junction protein 2
- Estrogen receptor
- Heterogeneous nuclear ribonucleoprotein U
Sequence:
MAETLSGLGDSGAASAAAVSSAASETGTRRLSDLRVIDLRAELRKRNLTSSGNKSVLMERLKKAIEEEGGNPDEIEVISEGNKKMPKRPSKGKKPEDEGVEDNGLEENSGDGQEDVETSLENLQDMDMMDISVLDEADIDNGSVADCVEEEEEATLPEGLGLLRIGRLQSKGLPEQLQELAIDDKEAINNVDTSSSDFTILQEMEEASLEPENEKILDILGETCKSEPVKEEGSELEQPFAQATSSVGPDRKLAEEEDLFESCGHPEEEEEEEEEEEQEEEQEEEGDLALASSSKSESSSTRCQWSEADALLAVVKREPAEAPGGGTGMDREPVGLEEPVEQSSTAAQLPETTSQELVRAPTAAPSPEPRDSKDDVKKFAFDACNDVPAAPKESSASEGADQKMSSVEDDSDTKRLSREEKGRSSCGRNFWVSGLSSTTRATDLKNLFSRYGKVVGAKVVTNARSPGARCYGFVTMSTAEEATKCINHLHKTELHGKMISVEKAKSEPAGKRVPDRRDGDSKKEKTSTSDRSANLKREEKGDRKDDAKKTDDGSTEKSKDADDQKPGPSERSRTTKSGSRGTERTVVMDKSKGVPVISVKTSGSKERASKSQDRKSVSREKRSVVSFDKVKESRKSRDSESRRERERERSEREQRLQAQWEREERERLEIARERLAFHRHRLERERMERERLERERMHVEQERRREQERIHREREELRRQQELRYEQERRPAVRRPYEVDGRRDDAYWPEAKRAALDDRYHSDFSRQDRFHDFDHRDRGRYPNHSVDRREGSRSMMGDREGQHYPERHGGPERHGRDSRDGWGYGSNKRLSEGRGLPLLPRRDWGEHARRLEDDRAWQGTADGGMMERDQQRWQGGERSMSGHSGPGHMMNRGGMSGRGSFAPGGASRRHVIPRGGMQAGFGGTEPGQQTQ
Protein: At3g52500 (Eukaryotic aspartyl protease family protein) (Q9SVD1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Probable cysteine protease RD21B
- Aspartic proteinase Asp1
- Phosphatidylinositol/phosphatidylcholine transfer protein SFH11
- Serine carboxypeptidase-like 34
- Serine carboxypeptidase-like 26
- Serine carboxypeptidase-like 42
- Alpha/beta-Hydrolases superfamily protein
- Prolyl carboxypeptidase like protein
- Serine carboxypeptidase-like 46
- Proteasome subunit alpha type-5-B
Sequence:
MASSIFFFFLIFLSVVSAVKLPLSPFSHSDQSPKDPYLSLRRLAESSIARAHKLKHGTSIKPDEDALSSTTTASATVVKSPLSAKSYGGYSVSLSFGTPSQTIPFVFDTGSSLVWLPCTSRYLCSGCDFSGLDPTLIPRFIPKNSSSSKIIGCQSPKCQFLYGPNVQCRGCDPNTRNCTVGCPPYILQYGLGSTAGVLITEKLDFPDLTVPDFVVGCSIISTRQPAGIAGFGRGPVSLPSQMNLKRFSHCLVSRRFDDTNVTTDLDLDTGSGHNSGSKTPGLTYTPFRKNPNVSNKAFLEYYYLNLRRIYVGRKHVKIPYKYLAPGTNGDGGSIVDSGSTFTFMERPVFELVAEEFASQMSNYTREKDLEKETGLGPCFNISGKGDVTVPELIFEFKGGAKLELPLSNYFTFVGNTDTVCLTVVSDKTVNPSGGTGPAIILGSFQQQNYLVEYDLENDRFGFAKKKCSP
Protein: Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin) (Q9R0Q1)
Organism: Mus musculus (Mouse)
Function: Modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary. Interacts with vesicles containing negatively charged phospholipids in a Ca(2+)-independent manner.
Subcellular location: Membrane {ECO:0000269|PubMed:10497219}; Peripheral membrane protein {ECO:0000269|PubMed:10497219}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000269|PubMed:10497219}; Peripheral membrane protein {ECO:0000269|PubMed:10497219}. Note=Detected close to the plasma membrane and on secretory granules. In pancreas, interacts with insulin-containing vesicles.
Interaction partners:
- Ras-related protein Rab-27A
- Syntaxin-binding protein 1
- Ras-related protein Rab-3A
- Ras-related protein Rab-27B
- Ras-related protein Rab-8A
- Unconventional myosin-Va
- Syntaxin-1A
- Syntaxin-3
- Syntaxin-binding protein 2
Sequence:
MSEILDLSFLSEMERDLILGVLQRDEELRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTCARCQEGLGRLIPKSSTCVGCNHLVCRECRVLESNGSWRCKVCSKEIELKKATGDWFYDQKVNRFDYRTGSEIIRMSLRQKPAVNKRETAGQSLLQQTQMGDIWPGRRIIQEQQQREQSVLFEVPKTRSGKSALEAESESLDSYTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKEIPPGNQNAVCGDEGDMVFKKNTKKVLRPSEYTKSVIDLRPEDVAQESGILGDRSKSVPGLSVDMEEEEEEEEDIDHLVKLHRQKLARGSMQSGSSMSTLGSIMSIYSEAGDFGNISVTGKIAFSLKFEQKTQTLVIHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETFRYEISESLLAQRTLQFSVWHHGRFGRNTFLGEAEVHMDSWKLDKKLDHCLPLHGKISTESSPGLPAHKGELVVSLKYIPASKLPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKSGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLSPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLRSSMVKQKLGV