wanglab/gogpt-training-data huggingface dataset:
Protein: Variant surface glycoprotein (VSG), putative (Q380V9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Interaction partners:
Sequence:
MKKQNFQSSPRLSVAEVKIAVAITLLAGSCKGAANDNAQAFNMMCGIRQILTAEADLPEQKDKEEVTRAIQQLIELNLSTAEDSMYDQKFEDDSSDGDKPQQYKENRPKWQKAKHLISAGNLEIDSIKILRLPNSPMRTTANKLINCSLEKAKALEKGLVEPTTQAEAQADFNDILFGDKAGEDKAGSKTYGTAATACGGNDPSNSEAGRSFMSDFLCLCSASGGSSPACTGTALSGITYSTASASATAAAALAKKCPLIPHTKTTAADIKAAAATFTAALKHKAGATTAGKIMLGKGDETQCNGAANGDCVLYKALDATGKLQIPWLSKFTAAISRLEAAHKNSLKNARIAAEVTNLKTAALRTYLQATVEVTQPPQPTKALSQQADKATQEPAKKVCNEAGGDQKACESLKDKDCTFNEKDKKCELKKEVKSKRENDCQEGKDGKTTNTNTTGSNSFVVNKAPLWLAFLLLA
Protein: Peroxidase 4 (Atperox P4) (EC 1.11.1.7) (ATP46) (Q9LE15)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular location: Secreted {ECO:0000255|PROSITE-ProRule:PRU00297}.
Interaction partners:
Sequence:
MAIFKILVLLLSLCCFSQAQLSPTFYDQTCQNALSTIRSSIRTAISRERRMAASLIRLHFHDCFVNGCDASVMLVATPTMESERDSLANFQSARGFEVIDQAKSAVESVCPGVVSCADIIAVAARDASEYVGGPRYDVKVGRRDSTNAFRAIADRDLPNFRASLNDLSELFLRKGLNTRDLVALSGAHTLGQAQCLTFKGRLYDNSSDIDAGFSSTRKRRCPVNGGDTTLAPLDQVTPNSFDNNYYRNLMQKKGLLESDQVLFGTGASTDSIVTEYSRNPSRFASDFSAAMIKMGDIQTLTGSDGQIRRICSAVN
Protein: Protein p13 MTCP-1 (p13MTCP1) (Mature T-cell proliferation-1 type B1) (MTCP-1 type B1) (P56278)
Organism: Homo sapiens (Human)
Function: Enhances the phosphorylation and activation of AKT1 and AKT2.
Interaction partners:
- RAC-alpha serine/threonine-protein kinase
- RAC-beta serine/threonine-protein kinase
- T-cell leukemia/lymphoma protein 1B
- T-cell leukemia/lymphoma protein 1A
- RAC-gamma serine/threonine-protein kinase
- Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial
Sequence:
MAGEDVGAPPDHLWVHQEGIYRDEYQRTWVAVVEEETSFLRARVQQIQVPLGDAARPSHLLTSQLPLMWQLYPEERYMDNNSRLWQIQHHLMVRGVQELLLKLLPDD
Protein: Nuclear migration protein nudC (Nuclear distribution protein C homolog) (Q9Y266)
Organism: Homo sapiens (Human)
Function: Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.
Subcellular location: Cytoplasm, cytoskeleton. Nucleus {ECO:0000269|PubMed:10210332}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:25789526}. Midbody {ECO:0000269|PubMed:25789526}. Note=In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern. Localizes to the mitotic spindle in a EML4-dependent manner (PubMed:25789526). {ECO:0000269|PubMed:23186163, ECO:0000269|PubMed:25789526}.
Interaction partners:
- Platelet-activating factor acetylhydrolase IB subunit beta
- Serine/threonine-protein kinase PLK1
- DnaJ homolog subfamily B member 1
- Nuclear distribution protein nudE homolog 1
- Nuclear distribution protein nudE-like 1
- Cytoplasmic dynein 1 heavy chain 1
- CAP-Gly domain-containing linker protein 1
- CLIP-associating protein 2
- Inner centromere protein
- Shugoshin 1
Sequence:
MGGEQEEERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFFIGGEEGMAEKLITQTFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSELDLAVPFCVNFRLKGKDMVVDIQRRHLRVGLKGQPAIIDGELYNEVKVEESSWLIEDGKVVTVHLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQEILKKFMDQHPEMDFSKAKFN
Protein: Linolenate hydroperoxide lyase, chloroplastic (EC 4.2.99.-) (Cytochrome P450 74B2) (Hydroperoxide lyase 1) (Q9ZSY9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the conversion of (9Z,11E,15Z)-(13S)-hydroperoxyoctadeca-9,11,15-trienoate to (9Z)-12-oxo-dodec-9-enoate and cis-3-hexenal. Possesses low activity toward (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate. Required for the synthesis of the green leaf volatiles (GLVs) hexanal and trans-2-hexenal.
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Interaction partners:
Sequence:
MLLRTMAATSPRPPPSTSLTSQQPPSPPSQLPLRTMPGSYGWPLVGPLSDRLDYFWFQGPDKFFRTRAEKYKSTVFRTNIPPTFPFFGNVNPNIVAVLDVKSFSHLFDMDLVDKRDVLIGDFRPSLGFYGGVCVGVNLDTTEPKHAKIKGFAMETLKRSSKVWLQELRSNLNIFWGTIESEISKNGAASYIFPLQRCIFSFLCASLAGVDASVSPDIAENGWKTINTWLALQVIPTAKLGVVPQPLEEILLHTWPYPSLLIAGNYKKLYNFIDENAGDCLRLGQEEFRLTRDEAIQNLLFVLGFNAYGGFSVFLPSLIGRITGDNSGLQERIRTEVRRVCGSGSDLNFKTVNEMELVKSVVYETLRFNPPVPLQFARARKDFQISSHDAVFEVKKGELLCGYQPLVMRDANVFDEPEEFKPDRYVGETGSELLNYLYWSNGPQTGTPSASNKQCAAKDIVTLTASLLVADLFLRYDTITGDSGSIKAVVKAK
Protein: Protein ORM1 (P53224)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the SPOTS complex that acts as a negative regulator of sphingolipid synthesis. Acts by inhibiting serine palmitoyltransferases (LCB1 and LCB2) activity.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:14562095}; Multi-pass membrane protein {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Serine palmitoyltransferase 1
- Protein ORM2
- Serine palmitoyltransferase-regulating protein TSC3
- Serine palmitoyltransferase 2
- Phosphatidylinositol-3-phosphatase SAC1
- Ceramide synthase LAC1
- Ceramide synthase LAG1
- Serine/threonine-protein kinase YPK2/YKR2
- Serine/threonine-protein kinase YPK1
- Flippase kinase 1
Sequence:
MTELDYQGTAEAASTSYSRNQTDLKPFPSAGSASSSIKTTEPVKDHRRRRSSSIISHVEPETFEDENDQQLLPNMNATWVDQRGAWIIHVVIIILLKLFYNLFPGVTTEWSWTLTNMTYVIGSYVMFHLIKGTPFDFNGGAYDNLTMWEQIDDETLYTPSRKFLISVPIALFLVSTHYAHYDLKLFSWNCFLTTFGAVVPKLPVTHRLRISIPGITGRAQIS
Protein: Spectrin beta chain (F6W8M4)
Organism: Macaca mulatta (Rhesus macaque)
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Interaction partners:
- Metabotropic glutamate receptor 1
- Spectrin alpha chain, erythrocytic 1
- Spectrin alpha chain, non-erythrocytic 1
Sequence:
MSSTLSPTDFDSLEIQGQYSDINNRWDLPDSDWDNDSSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGETLPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNAFNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHAMEAERLVEKYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFTEKGNLEVLLFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQEKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGRVQAVDAVAAELAAERYHDIKRIAARQHNVARLWDFLRQMVAARRERLLLNLELQKVFQDLLYLMDWMEEMKGRLQSQDLGKHLTGVEDLLQLHELVEADIAVQAERVRAVSASALRFCNPGKEYRPCDPQLVSERVAKLEQSYEALCELAAARRARLEESRRLWRFLWEVGEAEAWVREQQHLLASADTGRDLTGVLRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASARAAELQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPELGHDEFSTQALARQHRALEEEIRSHRPTLDALREQAAALPPALSRTPEVQGRVPTLERHYEELQARAGKRARALEAALALYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPEMNTLAAQITAVNDVAEQLLKASPPGKDRIVNTQEQLNHRWQQFRSLADGKKAALTSALSIQNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIASRVGELTREANALAAGHPAQAAAINARLREVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAWLGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRALGEEVTRDQADPQCLFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEMPGTLQAADAAIKKLEDFMSTMDANGERIHGLLEAGRQLVSEGNIHADKIREKADSIERRHRKNQDAAQQFLGRLRDNREQQHFLQDCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQAFMAELAANKDWLDKVDKEGRELTLEKPELKALVSEKLGDLHRRWDELETTTQAKARSLFDANRAELFAQSCCALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVEAIQAQAKALAQEDQGAGEVERTSRAVEEKFRALCQPMQERCRRLQASREQHQFHRDVEDEILWVTERLPMASSMEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLRERQRALGAAAAGPELAQLQEMWKRLGHELELRGKRLEEALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDELSAQAEVKKHQVLEQALADYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLKELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFSRDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAAYELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSAQVQQVQDDGHRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELMLWMDEVNLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYAAEEISEKLSQLQARRQETAEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAELGCTVDEVESLIKRHEAFQKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPAPEPTASVPPGDLVGGQTAPDTTWDRTQLRPPPSTQAPSVNGVCTDGEPSQPLLGQQRLEDSSSPEGPGPGPGDEANGPRGDRQTRTRGAAPPAMPQSRSTESAHAATLPPRGPEPSAQEQMEGVLCRKQEMEAFGKKAANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLARAQGSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATASSASGEPEEPVVPSTTRGMTRAMTMPPVSPVGAEGPVVLRSKDGREREREKRFSFFKKNK
Protein: Zinc finger protein 42 (Zfp-42) (Reduced expression protein 1) (REX-1) (mREX-1) (P22227)
Organism: Mus musculus (Mouse)
Function: Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST. Binds DXPas34 enhancer within the TSIX promoter. Involved in ES cell self-renewal.
Subcellular location: Nucleus {ECO:0000269|PubMed:16960129}.
Interaction partners:
- Homeobox protein NANOG
- POU domain, class 5, transcription factor 1
- RING1 and YY1-binding protein
- Steroid hormone receptor ERR2
- Transcriptional repressor protein YY1
- Developmental pluripotency-associated protein 4
- Developmental pluripotency-associated protein 5A
- Nuclear receptor subfamily 0 group B member 1
- E3 ubiquitin-protein ligase RING2
- Polycomb protein EED
Sequence:
MNEQKMNEQMKKTAKTSGQKGPGGRALDRLTLKQDEARPVQNTRVEAPRVTYTIRDESEISPETEEDGFPDGYLECIIRGEFSEPILEEDFLFKSFESLEEVEQNLSRQVLEASSLLESSLEYMTKGTKQEKTEVTQETPPLRVGASSLLAGGPAEKPEGGVYCGVLSMLECPQAGCKKKLRGKTALRKHMLVHGPRRHVCAECGKAFTESSKLKRHFLVHTGEKPYQCTFEGCGKRFSLDFNLRTHIRIHTGERRFVCPFDGCEKSFIQSNNQKIHILTHAKAGKKC
Protein: MADS domain protein (Q6EUV7)
Organism: Gerbera hybrida (Daisy)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MGRGRVELKRIENKINRQVTFAKRRNGLLKKAYELSVLCDAEVALIIFSNRGKLFEFCSTSNMLKMLERYQNCTYGSMEVDRSTPNAEQSSYKEYMKLKAKYESLQQYQRQLFGEDLGPLSLKELEQLERQLDSTLRQIRSIRTQSMLDRLSELQVKERMWVEANKALQNKLEEVYAENQAGPSWAAGEHHSSYGQEHQHQHQSQGFFQPLDCNSNLQIGYNTVDSSHITASTNGQNLNGLIPGWML
Protein: NADH-ubiquinone oxidoreductase 21 kDa subunit, putative (AFU_orthologue AFUA_4G05910) (Q5B580)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
- NADH-ubiquinone oxidoreductase 299 kDa subunit, putative
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH-ubiquinone oxidoreductase 78 kDa subunit
- NADH-quinone oxidoreductase subunit D domain-containing protein
- NADH dehydrogenase 1 alpha subcomplex subunit
- 4Fe-4S ferredoxin-type domain-containing protein
- NADH-ubiquinone oxidoreductase 30.4 kDa subunit, mitochondrial [Precursor]
- NADH dehydrogenase iron-sulfur protein 4
- NADH dehydrogenase 1 alpha subcomplex subunit 13
- NADH-ubiquinone oxidoreductase 24 kDa subunit, mitochondrial [Precursor]
Sequence:
MARNVVNAAKSASNVVSIKHKYSVQSTGLWERLRRILAIDPERSTGVPLNSQFRLPTPGALPPLSYDDPVTVPAGDIADNPYWKRDVRRNYPRVSTVNQADAVGLLTVGSQAAPKEEVLQIGEAGEKQLISLKQHGEERGLAGLFQKDKNGIRGVLGPNGLPPTPCNLNSSSKYQIDDDHGYPNVYPCRTFA
Protein: GB1/RHD3-type G domain-containing protein (Q3U2C0)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
RRAEVSLRRQQQLRTALGPVLWDQIHLCWQVAMTQPQMAPICLVENHNEQLSVNQEAIEILDKISQPVVVVAIVGWSHTGKSYLMNCLAGQNHVSGTLPTSQRFDWLCHISLILIPNYNNGQQNSFKQSHPLMLIFIP
Protein: Aquaporin-like protein 2 (Truncated aquaporin-2) (P0CD90)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Water channel required to facilitate the transport of water across membranes. Involved in freeze tolerance, osmotolerance and cell flocculation in liquid cultures (By similarity). Is non-functional in most laboratory strains.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:14562095}; Multi-pass membrane protein {ECO:0000269|PubMed:14562095}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Putative uncharacterized protein YLL053C
Sequence:
MSNESNDLEKNISHLDPTGVDNAYIPPEQPETKHSRFNIDRDTLRNHFIAAVGEFCGTFMFLWCAYVICNVANHDVALTTEPEGSHPGQLIMIALGFGFSVMFSIWCFWWGFEPSRFSLFVFGQSHLTSQMCSDVVSSDHCWDGCWWCR
Protein: FA complementation group I (H3BP78)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XIQLTSMFKDVPLTAEEVEFVVEKALSMFSKMNLQEIPPLVYQLLVLSSKGSRKSVLEGIIAFFSALDKQHNEEQSGDELLDVVTVPSGELRHVEGTIILHIVFAIKLDYELGRELVKHLKVGQQGDSNNNLSPFSIALLLSVTRIQRFQDQVLDLLKTSVVKSFKDLQLLQGSKFLQNLVPHRSYVSTMILEVVKNSVHSWDHVTQGLVELGFILMDSYGPKKVLDGKTIETSPSLSRMPNQHACKLGANILLETFKIHEMIRQEILEQVLNRVVTRASSPISHFLDLLSNIVMYAPLVLQSCSSKVTEAFDYLSFLPLQTVQRLLKAVQPLLKVSMSMRDCLILVLRKAMFANQLDARKSAVAGFLLLLKNFKVLGSLSSSQCSQSLSVSQVHVDVHSHYNSVANETFCLEIMDSLRRCLSQQADVRLMLYEGFYDVLRRNSQLANSVMQTLLSQLKQFYEPKPDLLPPLKLEACILTQGDKISLQEPLDYLLCCIQHCLAWYKNTVIPLQQGEEEEEEEEAFYEDLDDILESITNRMIKSELEDFELDKSADFSQSTSIGIKNNICAFLVMGVCEVLIEYNFSISSFSKNRFEDILSLFMCYKKLSDILNEKAGKAKTKMANKTSDSLLSMKFVSSLLTALFRVLLWRYTSIPTSVEESGKKEKGKSISLLCLEGLQKIFSAVQQFYQPKIQQFLRALDVTDKEGEEREDADVSVTQRTAFQIRQFQRSLLNLLSSQEEDFNSKEALLLVTVLTSLSKLLEPSSPQFVQMLSWTSKICKENSREDALFCKSLMNLLFSLHVSYKSPVILLRDLSQDIHGHLGDIDQDVEVEKTNHFAIVNLRTAAPTVCLLVLSQAEKVLEEVDWLITKLKGQVSQETLSEASSQATLPNQPVEKAIIMQLGTLLTFFHELVQTALPSGSCVDTLLKDLCKMYTTLTALVRYYLQVCQSSGGIPKNMEKLVKLSGSHLTPLCYSFISYVQNKSKSLNYTGEKKEKPAAVATAMARVLRETKPIPNLIFAIEQYEKFLIHLSKKSKVNLMQHMKLSTSRDFKIKGNILDMVLREDGEDENEEGTASEHGGQNKEPAKK
Protein: Protein KRTCAP2 homolog (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2) (Oligosaccharyl transferase subunit KCP2) (Q1HQF8)
Organism: Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
Function: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
- Oligosaccharyltransferase complex subunit
Sequence:
MAVPTSVSLVLASVTAVLIFSAMQMYKPLIASSQMATVFGGFLGSWLFILSLTAVSNLEAVVLGKGFQAKLFPEVAFCLIGSLFACGMVHRVCATTCILFSVAALYYINRISQKVHNAPVPVDTYAGKKKKK
Protein: Glucan endo-1,3-alpha-glucosidase agn1 (EC 3.2.1.59) (Endo-1,3-alpha-glucanase agn1) (O13716)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has a role in cell separation where it is required for the degradation of the cell wall material surrounding the septum (the septum edging) which must be hydrolyzed before full separation of the daughter cells can occur. Hydrolyzes 1,3-alpha-glucan predominantly into pentasaccharides.
Subcellular location: Secreted {ECO:0000269|PubMed:15194814}. Secreted, cell wall {ECO:0000269|PubMed:15194814}. Note=Associates with the cell wall.
Interaction partners:
- Primary septum glucan endo-1,3-beta-D-glucosidase
- Septin ring organizing protein mid2
- Protein adg1
- Serine/threonine-rich protein adg2
- Probable secreted beta-glucosidase adg3
- Metallothionein expression activator
- GTP-binding protein rho4
- Chitin synthase regulatory factor 1
- Forkhead protein sep1
- Rho guanine nucleotide exchange factor gef3
Sequence:
MKLVLFLVLLFSALINLTNADKMVVAHFIVGNTYPYTVSNWEEDIQDAIAVGIDGFALNMGSDAWQVERIEDAYDAAASVSSDFKLFISFDMSIISADADFIEGVVRRFADKPNQLYYDGKVFVSTFAGETDTFGYSDVSTGWDSAVKEPLASAGYPIYFVPSWTSLGQGALEESVADGFLSWNAWPTTDADMNDNDDIGYQNLANSLGKLYVAPVSPWFYTHLSYKNWAYKSDWLIIDRWNEMLSVQPDMIEVLTWNDYGESHYIGNIQGALPAGSEGYVDGFDHTAWRYLMSPYISAYKLGLSEPYINFESLFYWYRPTPKSATATADSLSYPSGGDYMEDEIFVLVYLLQSAEVTVTCGSTTQTFSGVPGVNQFTIPMETNASPSFTVARQGGTLASGTGPEIVDSLSIYNFNAYTGVLYF
Protein: glutathione transferase (EC 2.5.1.18) (C8BLR5)
Organism: Meleagris gallopavo (Wild turkey)
Interaction partners:
Sequence:
MSEKPRLTYINGRGRMESIRWLLAAAGVEFEEIFLQTREQLLKLGQDGSLMFHQLPLVEIDGMKLVQCRAILSYIAGKYNLYGKDLKERALIDMYVEGISDLMQLILMFPFSPPEAKEKNIATISEKATERYFPVFEKVLKQHGQDFLVGNRFSWADVQLMEAILAVEEKVPSVLSGFPQLQAFKTKMSNMPTIKKFLQPGSPRKPPPDENYVATVMKIFKLD
Protein: Acyl-coenzyme A thioesterase 3 (Acyl-CoA thioesterase 3) (EC 3.1.2.2) (PTE-Ia) (Peroxisomal acyl-coenzyme A thioester hydrolase 2a) (Peroxisomal long-chain acyl-CoA thioesterase 2) (Q9QYR7)
Organism: Mus musculus (Mouse)
Function: Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Mainly active on long-chain acyl-CoAs. May have a function in termination of beta-oxidation of fatty acids.
Subcellular location: Peroxisome {ECO:0000269|PubMed:15007068}.
Interaction partners:
- Peroxisomal succinyl-coenzyme A thioesterase
- Cytosolic acyl coenzyme A thioester hydrolase
- Acyl-coenzyme A thioesterase THEM5
- Acyl-coenzyme A thioesterase THEM4
- Fructose-1,6-bisphosphatase 1
- Acyl-coenzyme A thioesterase 1
- Acyl-coenzyme A thioesterase 2, mitochondrial
- Very-long-chain enoyl-CoA reductase
- Acyl-coenzyme A thioesterase 5
- Fructose-1,6-bisphosphatase isozyme 2
Sequence:
MHAFTTQNPNRMAPTVILEPAGGCLCDQPVHIAVRGLAPEQPVTLRSVLRDEKGALFRAHARYRADSHGELDLARTPALGGSFSGLEPMGLLWAMEPDRPFWRLIKRDVQTPFVVELEVLDGHEPDGGQRLARAVHERHFMAPGVRRVPVREGRVRATLFLPPGTGPFPGIIDLFGIGSGLLEYRASLLAGKGFAVMALAYNNYEDLPKDMDIIHLEYFEEAVTYLLSHPQVTGSGVGVLGISKGGELGFAMASFLKNITAAVIINGSISNIGGNLQYKDETVPSVGINTKRVKRTKDGLKDIVDLLNNPLEGPDQKSLIPVERSDTAFLFLVGQDDHNWKSEFYAREASKRLQAHGKEKPQIICYPETGHHIEPPYFPLCKASLNSLVGGPVIWGGEPRAHAMAQVDAWQQLQTFFHNHLDGKKKTIPAKL
Protein: Transthyretin (Prealbumin) (TBPA) (P27731)
Organism: Gallus gallus (Chicken)
Function: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
Subcellular location: Secreted {ECO:0000269|PubMed:1833190, ECO:0000269|PubMed:8612621}.
Interaction partners:
- Retinol-binding protein 4
- Albumin
- Uncharacterized protein.
- Uncharacterized protein.
- Transthyretin
- Apolipoprotein A-I
- Uncharacterized protein.
- Alpha 2-HS glycoprotein.
Sequence:
MAFHSTLLVFLAGLVFLSEAAPLVSHGSVDSKCPLMVKVLDAVRGSPAANVAVKVFKKAADGTWQDFATGKTTEFGEIHELTTEEQFVEGVYRVEFDTSSYWKGLGLSPFHEYADVVFTANDSGHRHYTIAALLSPFSYSTTAVVSDPQE
Protein: Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 1) (HACD1) (Protein-tyrosine phosphatase-like member A) (Q9QY80)
Organism: Mus musculus (Mouse)
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:B0YJ81}; Multi-pass membrane protein {ECO:0000250|UniProtKB:B0YJ81}.
Interaction partners:
- Very-long-chain enoyl-CoA reductase
- Very-long-chain 3-oxoacyl-CoA reductase
- Very long chain fatty acid elongase 2
- Very long chain fatty acid elongase 4
- Acyl-CoA
- Very-long-chain
- Very long chain fatty acid elongase 5
- Very-long-chain
- Very-long-chain
- Trans-2,3-enoyl-CoA reductase-like
Sequence:
MGKGDWRQGRVEMPCAHVSRLHKTCVQVRVRVTMASSEEDGTNGASEASDEKEAAGKRRRLGLLATAWLTFYNIAMTAGWLVLAIAMVRFYMEKGTHRGLYKSIQKTLKFFQTFALLEVVHCLIGIVPTSVLVTGVQVSSRIFMVWLITHSIKPIQNEESVVLFLVSWTVTEITRYSFYTFSLLDHLPHFIKWARYNLFIILYPVGVAGELLTIYAALPYVKKSGMFSVRLPNKYNVSFDYYYFLLITMASYIPLFPQLYFHMLRQRRKVLHGEVIAEKDD
Protein: Small ribosomal subunit protein uS5 (30S ribosomal protein S5) (P9WH33)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: With S4 and S12 plays an important role in translational accuracy.
Interaction partners:
- Small ribosomal subunit protein uS13
- Small ribosomal subunit protein bS1
- Large ribosomal subunit protein bL35
- Small ribosomal subunit protein bS16
- Large ribosomal subunit protein uL3
- Large ribosomal subunit protein uL14
- Large ribosomal subunit protein uL29
- Small ribosomal subunit protein bS20
- Small ribosomal subunit protein uS17
- Large ribosomal subunit protein uL24
Sequence:
MAEQPAGQAGTTDNRDARGDREGRRRDSGRGSRERDGEKSNYLERVVAINRVSKVVKGGRRFSFTALVIVGDGNGMVGVGYGKAKEVPAAIAKGVEEARKSFFRVPLIGGTITHPVQGEAAAGVVLLRPASPGTGVIAGGAARAVLECAGVHDILAKSLGSDNAINVVHATVAALKLLQRPEEVAARRGLPIEDVAPAGMLKARRKSEALAASVLPDRTI
Protein: Serine/threonine-protein kinase sid1 (EC 2.7.11.1) (STE20-like kinase sid1) (O14305)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Has a role in the septation initiation network (SIN) required for cytokinesis.
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body {ECO:0000269|PubMed:10775265, ECO:0000269|PubMed:11384993}. Note=Localizes to the SPB prior to cytokinesis and leaves once septation is complete.
Interaction partners:
- Septation initiation network scaffold protein cdc11
- Cell division control protein 14
- Maintenance of ploidy protein mob1
- Mo25-like protein
- Septation initiation protein sid4
- Septum-promoting GTP-binding protein 1
- Protein byr4
- Cell division control protein 16
- Septation protein etd1
- Cell wall integrity protein scw1
Sequence:
MYPLNANSYTLLRKLGSGSFGVVWKARENVSGDIIAIKQIDLETGIDDITDIEQEVFMLSNCNSSNVIQYYGCFVDGYTLWILMEHMDGGSVSGLLKMGRLNEQVISIILREVLYGLNYLHGQNKIHRDIKAANILLSSSTGNVKLADFGVAAQLSNAASRRHTFVGTPFWMAPEVIQQTSYGLAADIWSLGITAIEMANGIPPRATMHPMRVIFEIPQSEPPKLDDHFSPTFRDFVSCCLDLNPNMRWSAKELLQHPFIKSAGTVKDIIPLLVQKENKLFDDSDQSVLEETINNTLKPFEEPIAEGNADIEDWTFETVKKSDSTVLGNTSIPKNSIISSQNKEELPSSIKYLEKTIMSDQATPHPFSKSLSEKGSSYHKSLTSDFAMKHYIKSTIRSMLLNDKLSATQRSSLESFYTSFISLDKNLSSKFVNQITPDNRLHHKKQKRSPISQLLFSRWLEETEKRRSLNG
Protein: Battenin (G5ECU8)
Organism: Caenorhabditis elegans
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}. Lysosome membrane {ECO:0000256|RuleBase:RU361113}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU361113}.
Interaction partners:
- Alpha-mannosidase
- Battenin
- Battenin
- hydroxymethylglutaryl-CoA lyase
- Probable beta-mannosidase
- Palmitoyl-protein thioesterase 1
- Coelomocyte uptake defective protein 15
- Sulfatase N-terminal domain-containing protein
- Chloride channel protein
- Sphingomyelin phosphodiesterase 1
Sequence:
MDVASGGGRRPPRNSVAFWLLGLCNNFAYVVMLSAAKDILEKDAKHIEKPCREHVTTRECQMMSTGSVLLADIIPALLIKITAPMFIHRVPFGIRHSIVVLLQASSFLIVGISDSTALALFGVVLASFGSGLGEISYLALSSNYPSTVVASWSSGTGGAGLIGASAYALLTDSKLLAISPKHTMFIMLTLPALFSVSYWSILKIPHSVQRAHFLQPSTWLVTGDFIPADDMRREEVEEEEGLLGIREDRENSVDVTSRRRQTSTTLERVLPLLKFMIPLISVYLAEYYINQGLLELLEFDCSHGFSMSSESQYRWFQVTYQLGVFISRSSSNYVTIPTQYLKSLAVLQIFNAGFFTITAIYSFLPHILIAFLVILFEGLLGGASYVNTFRAVHKEIPADSREFSMGVVSISDTIGIVFAGFLAMPVHNRICSMPM
Protein: ETS homologous factor (E9PPS9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MILEGGGVMNLNPGNNLLHQPPAWTDSYSTCNVSSGFFGGQWHEIHPQYWTKYQVWEWLQHLLDTNQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYSNLQHLKWNGDSLFLCLSLPC
Protein: Translation initiation factor IF-3 (P0A708)
Organism: Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00080}.
Interaction partners:
- Large ribosomal subunit protein bL20
- Small ribosomal subunit protein uS11
- Small ribosomal subunit protein uS13
- Small ribosomal subunit protein uS7
- Small ribosomal subunit protein uS2
- Small ribosomal subunit protein uS19
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein bS18
- Large ribosomal subunit protein uL13
- Small ribosomal subunit protein bS6
Sequence:
MKGGKRVQTARPNRINGEIRAQEVRLTGLEGEQLGIVSLREALEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGTDEGDYQVKLRSLIRFLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLQELAVVESFPTKIEGRQMIMVLAPKKKQ