wanglab/gogpt-training-data huggingface dataset:
Protein: Ribosomal protein S6 kinase beta-2 (S6K-beta-2) (S6K2) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 2) (P70S6K2) (p70-S6K 2) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14B) (p70 ribosomal S6 kinase beta) (S6K-beta) (p70 S6 kinase beta) (p70 S6K-beta) (p70 S6KB) (p70-beta) (Q9UBS0)
Organism: Homo sapiens (Human)
Function: Phosphorylates specifically ribosomal protein S6. Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7.
Subcellular location: Cytoplasm. Nucleus.
Interaction partners:
- Small ribosomal subunit protein eS6
- Serine/threonine-protein kinase mTOR
- Regulatory-associated protein of mTOR
- Insulin receptor substrate 1
- Target of rapamycin complex subunit LST8
- Proline-rich AKT1 substrate 1
- Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
- Eukaryotic translation initiation factor 4B
- 3-phosphoinositide-dependent protein kinase 1
- DEP domain-containing mTOR-interacting protein
Sequence:
MAAVFDLDLETEEGSEGEGEPELSPADACPLAELRAAGLEPVGHYEEVELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRAPVSPLKFSPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGTKKSKRGRGRPGR
Protein: Nuclear transcription factor Y subunit gamma (H0Y803)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
XPRDELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLAMETFFAFKRQIYSLWRVGGFIATLFSPRDPGN
Protein: Voltage-gated potassium channel subunit beta-2 (EC 1.1.1.-) (K(+) channel subunit beta-2) (Kv-beta-2) (hKvbeta2) (Q13303)
Organism: Homo sapiens (Human)
Function: Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability (By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity (By similarity). Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore. Promotes KCNA4 channel closure. Modulates the functional properties of KCNA5 (By similarity). Enhances KCNB2 channel activity (By similarity). Binds NADPH and has NADPH-dependent aldoketoreductase activity (By similarity). Has broad substrate specificity and can catalyze the reduction of methylglyoxal, 9,10-phenanthrenequinone, prostaglandin J2, 4-nitrobenzaldehyde, 4-nitroacetophenone and 4-oxo-trans-2-nonenal (in vitro) (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P62483}. Membrane {ECO:0000269|PubMed:11086297, ECO:0000269|PubMed:21357749}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cell membrane {ECO:0000250|UniProtKB:P62483}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cell projection, axon {ECO:0000269|PubMed:11086297}. Synapse, synaptosome {ECO:0000269|PubMed:21357749}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P62483}. Note=Recruited to the cytoplasmic side of the cell membrane via its interaction with pore-forming potassium channel alpha subunits. Associates with microtubules when unphosphorylated. {ECO:0000250|UniProtKB:P62483}.
Interaction partners:
- Potassium voltage-gated channel subfamily A member 2
- Potassium voltage-gated channel subfamily A member 1
- Potassium voltage-gated channel subfamily A member 3
- Potassium voltage-gated channel subfamily A member 4
- Potassium voltage-gated channel subfamily A member 5
- Potassium voltage-gated channel subfamily A member 6
- Voltage-gated potassium channel KCNC1
- A-type voltage-gated potassium channel KCND2
- 2-Hydroxyacid oxidase 1
- Voltage-gated potassium channel KCNC4
Sequence:
MYPESTTGSPARLSLRQTGSPGMIYSTRYGSPKRQLQFYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNADQLMENIGAIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS
Protein: VPS10 domain-containing receptor SorCS1 (mSorCS) (Q9JLC4)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane; Single-pass type I membrane protein.
Interaction partners:
- Insulin-1
- Insulin-2
- Vacuolar protein sorting-associated protein 26A
- Sortilin
- Vacuolar protein sorting-associated protein 35
- Zinc finger protein 69
- Amyloid-beta precursor protein
Sequence:
MGKVGAGDGSSAGLSALLAGAGLLMLLAPGVCSSLSCCPPQHPSSTPRRTLTPRGFPHPGPLGRAPATPPPLFMRPLFAVAPGDRALFLERAGGSRVSVATAARSGRRRRSGTEPEKIEPGEGASRSRRDMLKDGGQQGLGTGARDPGKATRFRMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNKCKIMLLTDPEIESSLLISSDEGATYQKYRLNFYLQSLLFHPKQEDWILAYSQDQKLYSSAEFGRRWQLIQESVVPNRFYWSVMGSSKEPDLVHLEARTVDGHSIYLTCRMQNCTEANRNKPFPGYIDPDSLIVQDDYVFVQLTSGGRPHYYVSYRRSPFAQMKLPKYALPKDMHVISTDENQVFAAVQEWNQNDTYNLYISDTRGVYFTLALENVRSSRGPEGNVMIDLYEVAGIKGMFLANKKIDNQVKTFITYNKGRDWRLLQAPDADLRGDPVHCLLPYCSLHLHLKVSENPYTSGIIASRDTAPSIIVASGNIGSELSDSDISMFVSSDAGNTWRQIFEEEHSILYLDQGGVLVAMKHTSLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFGHFSHRSEWQLVKVDYKSIFDRRCAEEDYRPWQLHSQGEACIMGAKRIYKKRKSERKCMQKYAGAMESEPCVCTEADFDCDYGYERHSNGQCLPAFWFNPSSLSKDCSLGQSYLNSAGYRKVVSNNCTDGVREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDGIAVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVLWPSQVGTLTYVWWYGNNTEPLITLEGSISFKFTSEGMNTITVQVSAGNAILQDTKTIAVYEEFRSLRLAFSPNLDDYNPDIPEWRRDISRVIKKSLVEATGIPSQHILVAVLPGLPTAAELFVLPYQDGTRENKRSPEDLEQISEVLIHKLNQNLVHFELKPGVQVLVHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRRVALPSPPSPSAQPGDSSLRLQRPRPATPPSSPKRGSAGAQFAI
Protein: Nickel transport protein NikQ (Energy-coupling factor transporter transmembrane protein NikQ) (ECF transporter T component NikQ) (D5AQY7)
Organism: Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
Function: Part of the energy-coupling factor (ECF) transporter complex NikMNQO involved in nickel import. The complex confers nickel uptake upon expression in E.coli; can also transport cobalt with a very low affinity.
Subcellular location: Cell inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Fused nickel transport protein NikMN
- Nickel import ATP-binding protein NikO
- Cobalt import ATP-binding protein CbiO
- Cobalt transport protein CbiM
- Cobalt transport protein CbiN
- Cobalt transport protein CbiQ
- Biotin transport ATP-binding protein BioM
- Biotin transporter BioY
- DUF4198 domain-containing protein
- Energy-coupling factor transporter transmembrane protein BioN
Sequence:
MTDPSVVHARAPAPDRIGRLGAGVRGLMQHAEEAAGLAQRPGLLQGLDPRAKVAGAFALILAAVATRSLLVLLALFVLATALAAASQISPARLARQVWIVVLGFTGMIALPALILVPGTPVLSLPFGLAITEQGLRAAAFLTGRSETTATLALALVLTTPWPQVLKALRCLGVPRAAVMILGMTHRYIFVLADLALDLFEARRSRLVGRLSPAEARRLATGIAGALFERALALSSEVHLAMLARGWRGEVHLIDDFRFRPRDGGALVLAAAILAGVVWAGSVWP
Protein: Trafficking protein particle complex subunit (Q381J3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Endoplasmic reticulum {ECO:0000256|RuleBase:RU366065}. Golgi apparatus, cis-Golgi network {ECO:0000256|RuleBase:RU366065}. Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}.
Interaction partners:
- Trafficking protein particle complex subunit
- Transport protein particle
- Transport protein particle
- Trafficking protein particle complex subunit
- Trafficking protein particle complex subunit
- Uncharacterized protein
- Trafficking protein particle complex subunit 11 C-terminal domain-containing protein
- COP9 signalosome complex subunit 4
- Trafficking protein particle complex subunit 11 domain-containing protein
- Trafficking protein particle complex subunit 11 domain-containing protein
Sequence:
MTVHLLWIINQSGQLIAKSSFTAQNSIGELGAKPDLQLTMSSILFSTFGMSQELTPNANPVDSAGMTLLEFAEHNVHIYETPSLVKFVLVSDHHTYECNALFRQLHSLYVEYVVKNPFNIIDEGGIGQPIRIPAFTEAVKEAVDKYHSHTQQPAVKR
Protein: Nuclear hormone receptor family member nhr-2 (Q10902)
Organism: Caenorhabditis elegans
Function: Orphan nuclear receptor.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
Interaction partners:
- Nuclear receptor corepressor 1
- Forkhead box protein fkh-4
- Homeobox protein ceh-39
- Hand transcription factor 1
- C2H2-type domain-containing protein
Sequence:
MVPMNPELMHYPNQPHMMPGYPMINAYQQSYLQNPAQWTPEMLLCMQMQMQQMVPGTATNSTYMPPQSKNTVTPNATSPLSQISDRDSGNDTISPPLTSQNSATTPNYHNQPQMQLTPLQQAKPEKEEISPYAINNILSSTQSSPDNGNEADDKENSSVRRNTFPASSASTKKPRGTPYDRTNTPMTVVPQMPQFAPDFSNYNLTMNAWSEFFKKDRCMVCGDNSTGYHYGVQSCEGCKGFFRRSVHKNIAYVCTKGENCTFSYENCAANRGVRTRCQACRFAKCLAVGMNRDNVRVNKETDKDVKPSVASPNFEMTSQVKELTAAFVANMPCSTHLTSGTHAIGAIKKFIESVPALSSLLPKDEKALEMSIQKVMSGILAIRAAFTFDPITFYSCENPVNLLRGGIRNTVFNDCEVALLSGIHILQIVNGGVAEIFTSYCQGLRHQLSQTHLQEIGLCDRLLMRLGPYLNQ
Protein: AvrSen1 (A0A507D1H9)
Organism: Synchytrium endobioticum
Interaction partners:
Sequence:
MANPPIIKMGKNVKIVVVAALLIFFTLTQSAPARTTEEEIAACLTGISDLRHHLKIEMARVEENTTSQSSYRGVTRRTLGTERGTLREALESTDHWSIELTYEQLKKLAITDRRWLPVCIAHEYLIVERAQYDMERLKHYMSHVQSAYEDSTKARAARRLSLYNALIKVHESKIADLLLRSGTVGTSELMVASTVYVDRPTLDLLEPHREDDGDAPHPIMFDFFRLADEQPVESRLEDYSNFIVEREEIRETVRGGDTVGTSDPMVTSTYYVDRPTLDLLGRGGIDRTSDLIDRPLFDFLGQSDEQLLRLSLGTYNPKRYEAPTARFKEPSLSLSPTYYHAVEPSTRIHNDRNRGKMPMYDDSTPPSYPPYYAID
Protein: ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) (Caseinolytic protease) (Endopeptidase Clp) (Heat shock protein F21.5) (Protease Ti) (P0A6G7)
Organism: Escherichia coli (strain K12)
Function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. May play the role of a master protease which is attracted to different substrates by different specificity factors such as ClpA or ClpX. Participates in the final steps of RseA-sigma-E degradation, liberating sigma-E to induce the extracytoplasmic-stress response. Degrades antitoxin MazE.
Subcellular location: Cytoplasm.
Interaction partners:
- ATP-dependent Clp protease ATP-binding subunit ClpX
- ATP-dependent Clp protease ATP-binding subunit ClpA
- ATP-dependent protease ATPase subunit HslU
- ATP-dependent protease subunit HslV
- Lon protease
- Chaperone protein ClpB
- Chaperonin GroEL
- ATP-dependent Clp protease adapter protein ClpS
- Chaperone protein DnaK
- Co-chaperonin GroES
Sequence:
MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVKGRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN
Protein: CDKN1A interacting zinc finger protein 1 (A0A494C0L7)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSETYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPTTRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKAL
Protein: Magphinin-alpha (Q99PM5)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MDKTTPAPPPVPSANDNASNKPKVTLQALNLPMFTQISQASATTEAPNIQASVTSQTQKAKTMRVTPKVSLTGSEDATTQLKPPLQALNLPVTTPTIQTPVANESANSLASTAVNKSKKASTANNAANKTVPSAAEISLASAATHTATTQGQAAKETGSIQTIAATARSKKNSKGKRTPAKTTNTDNEYVEASNAIEASSRQIGASGRQTEASNRQIEASSRQTEASNRQTEASSRQTEASSRQTETSNRQIGASNRQIMASNRQIGASNRQIEASNRQIGASNRQTEVSSRQIEASNRQIGASNRQTEASNRQIGASNRQTEASNRQIGASNRQTDASNRQTEASSRQTEASSRQTEASSRQTEASSRQIEASAAAVRPKKPRGKKGNNKGSNSASEPSEAPPAIQTVTNHALSVTVRIRRGSRARKAANKNRATESQAQIAEQGAQASEASISALETQVAAAVQALADDYLAQLSLEPTTRTRGKRNRKSKHPNGEERTGNNYRRIPWGRRLPPPRDVAILQERANKLVKYLLVKDQTKIPIKRSDMLKDVIQEYEDYFPEIIERASYALEKMFRVNLKEIDKQNNLYILISTQESSAGIMGTTKDTPKLGLLMVILSVIFMNGNKASEAVIWEVLRKLGLHPGVKHSLFGEVKKLITDEFVKQKYLEYKRVPNSRPPEYEFFWGLRSYHETSKMKVLKFACKVQKKDPKDWAAQYREAVEMDIQAAAVAVAEAKARAEARAQMGIGEEAVAGPWNWDDMDINCLTSGGPSTGAGFCSGPSTGGFGGGPSTGPGFGGPSTGPGFGGPSTGGGFGGPNTGGGFGGPSTGGGFGGPSTGGGFGGPSTGGGFGGPSTAAGFGSGLSTSTGFGGGLNTSAGFSGGPPSTGTGFGGGASSHGGCGFPYG
Protein: Bonus, isoform E (A0A0B4KHT0)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MDMDLEQLKNDFLPLIAGIKQEQLDAVPTDALPQMSTPNTASGAPTTSSLSSSSLSLSNPCDSAEKRSESNSSASAKFTLFKCVYCAQLLGSNDRPKLLECLHVACAQCVSTKFSELDRSLPPLIHCPVCDNASQQEFIVDNQFLIEQCTAGDSGDGVGLLGLTGEGQKSSAAASIQCSSCSDGAVATSWCVDCSEYICDSCVQAHQRLKITKDHTIKPKDEANNEQLAGAAGVDKLHMCQLHPQEKLSLFCETCDKLTCRDCQLSDHRDHKYKFAHEIATESRQALSTLVSEINYKRFLLSSATKVIDDRQQLIHDKKKDLIKEITAMAVKITNTVNTRGKQLIMRLNEVCDSKLKVLVEKKETLQLLSDNTDHCIDFMQNALEKGSDFAILSSKKSLVRHLQKLKCQRADIPNPEIPVRIQVQLNQVSDLQKVISQLGIIIVDGKPYPPTPSPNGTPQPQHPPRQPPSPNMAPPLRPGLPPGMPAGLSPNGPPVNFGPQNGPPLYSNAAQQQFNNLSMSRSFPGDGSGKVRFGGMPPVGMQRHGQPHVSSSTHPQNMDISLRGLLNNQAAQSPNAHMAFNGPPSYPGGPQGAPAPAHQPMGPQMRPHFMPGQQGFSQGGGPGGGPRDANFMNSNARFQSQYQRMANHAQQAAAAAAMAGAAGGGGGQIPSPGALQRPQMMSNPMQNVSAMQNSLGFHGSQAGFNTGPPQTSPQLGGGGMHSLAKWHIPQSAQQSNMCSQQGPLLPFANGRQTSENFKISLKSPNTLKNSTPPSLGGGGAGHQGHGNGSSSAQLNAAALGLGPAVSILSNVTSTNPKTPSPSTHENTKDFTEPIDKVRDDSINDLIATIAKLDSNGVQVLPEGRTKTTSPQVHSSTDLSNTQEDDPNEDWCAVCLDGGELMCCDKCPKVFHQNCHIPAISSLPDESESWQCLLCVNIKELTKTEGSEKSSSGELSALELRILQRICLELYCQYEQSLNFREPESPANTSYYEIVSSPMSLDVIRTRLDPSSPNHYKDIAGFVSDVRLIFSNTYLFYQEDTKTYSNAKYLENFFEEQLAKWLPQFEGTKPQGKRNTSNSPALLGVNATGSPSPIENGRKSCGSASLGDSDGACLPAKRARRSAHE
Protein: PslL (Q9I1M8)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Interaction partners:
- PslJ
- PslE
- PslH
- PslG
- PslF
- PslD
- PslI
- PslA
- dTDP-Rha:alpha-D-Gal-diphosphoundecaprenol alpha-1,3-rhamnosyltransferase
- FAD-dependent oxidoreductase 2 FAD-binding domain-containing protein
Sequence:
MLGSAFWLTLATLLGLCLGFAREWLLVASWGAGERSDAFLIALFLPEALRMSLAGGVLSAAALPLFLERQGERRLDWLAAILPALLGIAVALSLLLLAAAPWLVRLLGPGLAETASAQAAANLRVLAWCVPGLMLHALFSIPLQAAERFVLAGLGSLLFNLPPVLYLALHGQASQPEQLALACLLGSLLMPLVLLPSLWIEGWRPWHWRLSGVELGELGGRIAPLLLSNAASQGLALVERLVASLLGEGAVTWVNLARKLMNLPLIALMSLNQVLLGMMSRRQGGERLALLRRGLETASLLTLPAGVGLVAAAPGLVALLLPRQTAGSPLPALLAWFAVPLVFGAWNALLARYAYAAGDTRLPLRCELLGSALNAALLAVLPLIFGLPGIPLAALGGVLCTALLLMRRQALLGALPWARLWLLNALAMALAAGLLFRIDGIWLQLGLGTVAGCLALLGMALWLRPWRTD
Protein: Myosin-binding protein 3 (Q0WNW4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Membrane-anchored myosin receptors that define a distinct, plant-specific transport vesicle compartment.
Subcellular location: Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}.
Interaction partners:
- Kinesin-like protein KIN-14I
- Kinesin-like protein KIN-14K
- Kinesin-like protein KIN-14J
- Villin-1
- Myosin-17
- Myosin-6
- Myosin-5
- Kinesin-like protein KIN-14L
- Kinesin-like protein KIN-14H
Sequence:
MAANNFATKLSRNTNRITVILVYAFLEWLLMFFIFLNSFFTYFIVKFASFFGLKQVCLLCPKLDRIFERKPENRFTYKELLCQNHIAELASLSFCRTHGKLSESANLCSDCSNREEEQSNIGLGFCTCCQKSLADKPYPNYLLLKSSIWGKTLGDREDGGLILEMIDDDKFGDGFEIDRESYPLGFFRDKAEEGKKQDQQQNGEVISDVESYGLSLREVSEEDGLRSIISNNSPGNEAKSRVSEDEQRNDDTSNVATYGEDQISGRVEEKEEETGVADLLYDQFESKNFTGSQIEEEEEDREETTKELDPETPTSVSTLFNKKLHFLARNEYAAAEDAGDGNVLVSEMDGGDPLRTIERLRETVRAEQEALRDLYAELEEERSASAISANQTMAMITRLQEEKAKVQMEALQYQRMMEEQAEYDQEALQLLNHLMVKREKEKEQLQRELEVYRAKVLEYESKAKNKIIVVENDCEADDDDKEEENREEDNSSEMDVDLEKITLDCVQHMSMLGESLSEFEEERLVILDQLKVLEDRLVTMQDKESAEDPGEFSNSYEEASNGHGGLTMASMAKSLLPLLDAAENESEDGSQGLPESDEKNFGSDSEKLEIIKQVDSVYERLQELETDGEFLKNCMSSAKKGDKGTDILKDILQHLRDLRTIELTNTIENQTTQEE
Protein: Taste receptor type 2 member 16 (T2R16) (Q9NYV7)
Organism: Homo sapiens (Human)
Function: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
Subcellular location: Cell membrane {ECO:0000269|PubMed:16720576}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Taste receptor type 2 member 38
- Guanine nucleotide-binding protein G
- Taste receptor type 1 member 1
- Taste receptor type 1 member 3
- Taste receptor type 1 member 2
- Muscarinic acetylcholine receptor M2
- All-trans-retinol dehydrogenase [NAD
- Taste receptor type 2 member 9
- Taste receptor type 2 member 1
Sequence:
MIPIQLTVFFMIIYVLESLTIIVQSSLIVAVLGREWLQVRRLMPVDMILISLGISRFCLQWASMLNNFCSYFNLNYVLCNLTITWEFFNILTFWLNSLLTVFYCIKVSSFTHHIFLWLRWRILRLFPWILLGSLMITCVTIIPSAIGNYIQIQLLTMEHLPRNSTVTDKLENFHQYQFQAHTVALVIPFILFLASTIFLMASLTKQIQHHSTGHCNPSMKARFTALRSLAVLFIVFTSYFLTILITIIGTLFDKRCWLWVWEAFVYAFILMHSTSLMLSSPTLKRILKGKC
Protein: Sulfotransferase 1C2 (ST1C2) (rabSULT1C2) (EC 2.8.2.1) (Sulfotransferase 1C1) (O46503)
Organism: Oryctolagus cuniculus (Rabbit)
Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. Sulfonates p-nitrophenol, a small phenolic compond. Does not sulfonate steroids, dopamine, acetaminophen, or alpha-naphthol.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10481272}. Lysosome {ECO:0000250|UniProtKB:Q9WUW8}. Mitochondrion {ECO:0000250|UniProtKB:Q9WUW8}.
Interaction partners:
Sequence:
MALATGPGKQTQLREVEGVPLQAAIVDNWGQIQSFEAKPDDLLICTYPKSGTTWIQEIVDMIEQNGDVEKCQRALIQHRHPFIEWARPPQPSGVEKAQAMPSPRILRTHLPTRLLPPSFWENNCKFLYVARNVKDCMVSYYHFQRMNQVLPDPGTWEEYFETFINGKVAWGSWFEHVKGWWEVKGRYQILFLFYEDIKKDPKCEIRKVAQFMGKHLDETVLDKIVQETSFEKMKDNPMINRSTVPKSIMDQSISPFMRKGTVGDWKNHFTVAQSHRLDELYRKKMEGVSIDFCLEL
Protein: Spermidine/putrescine transport system permease protein PotB (P0AFK4)
Organism: Escherichia coli (strain K12)
Function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine.
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Interaction partners:
- Spermidine/putrescine-binding periplasmic protein
- Putrescine transport system permease protein PotI
- Spermidine/putrescine import ATP-binding protein PotA
- Spermidine/putrescine transport system permease protein PotC
- Putrescine transport ATP-binding protein PotG
- Inner membrane ABC transporter permease protein YdcV
- Putrescine-binding periplasmic protein PotF
- Uncharacterized ABC transporter ATP-binding protein YdcT
- sn-glycerol-3-phosphate import ATP-binding protein UgpC
- Maltose/maltodextrin import ATP-binding protein MalK
Sequence:
MIVTIVGWLVLFVFLPNLMIIGTSFLTRDDASFVKMVFTLDNYTRLLDPLYFEVLLHSLNMALIATLACLVLGYPFAWFLAKLPHKVRPLLLFLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIDTPIRIMFTPSAVIIGLVYILLPFMVMPLYSSIEKLDKPLLEAARDLGASKLQTFIRIIIPLTMPGIIAGCLLVMLPAMGLFYVSDLMGGAKNLLIGNVIKVQFLNIRDWPFGAATSITLTIVMGLMLLVYWRASRLLNKKVELE
Protein: DNA polymerase delta subunit 2 (C9JLE1)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MFSEQAAQRAHTLLSPPSANNATFARVPVATYTNSSQPFRLGERSFSRQYAHIYATRLIQMRPFLENRAQQHWGSGVGVKKLCELQPEEKCCVVGTLFKAMPLQPSILREVSEEHNLLPQPPRSKYIHPDDELVLEDELQRIKLKGTIDVSKLVTGTVLAVFGSVRDDGKFLVEDYCFADLAPQKPAPPLDTDRFVLLVSGLGLGGGGGESLLGTQLLVDVVTGQLGDEGEQCSAAHVSRVILAGNLLSHSTQSRDSINKAKYLTKKTQAASVEAVKMLDEILLQLSASVPVDVMPGEFDPTNYTLPQQPLHPCMFPLATAYSTLQLVTNPYQATIDGVRFLGTSGQNVSDIFRYSSMEDHLEILEWTLRVRHISPTAPDTLECPHVYFCGNTPSFGSKIIRGPEDQTVLLVTVPDFSATQTACLVNLRSLACQPISFSGFGAEDDDLGGLGLGP
Protein: Wiskott-Aldrich syndrome protein family member (WASP family protein member) (Q9XVK6)
Organism: Caenorhabditis elegans
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|RuleBase:RU367034}.
Interaction partners:
- Membrane-associated protein gex-3
- Cytoplasmic FMR1-interacting protein homolog
- SH3 domain-containing protein
- Protein BRICK1
- Ras-related protein ced-10
- Actin-related protein 2
- Transducer of Cdc42-dependent actin assembly protein 1 homolog
- Transducer of Cdc42-dependent actin assembly protein 2 homolog
- Cell division control protein 42 homolog
- UNC-34
Sequence:
MPLTKRAVSPVNLSRGTIPSTIHRDELQCTANGTIANLVRQLSSLSKHAENIFGEIYHDAMIINHKSNTLQQRIDRLHKKVEDLDSNSDQATLNEANMRKAFKSSMLVDQHILDRSTLPTALTEIYAKCDPPPDLDALNPYRDSEIPALSLYTNPSFFFDLWKKETLKEVAERPRRVKSPNDGSKSPKKRRKQPGQGPLGTTAYNDMQHRNRQISGSRINQQNEVFSFPEEYQAPQALGLQLNFKNQHPSNMVAPIGMTMHHHPQQNVHPSQQRGGAPAAARGSPNVKRPTEAPPPVNLDHLPPPDMSILSIDDDDDDLPPPPPPLLMNTSIVHQLPAEAPSTIQFVEPSAAPPTNIPPPPPPPPPMVISSAAASFAAPAPKPSADGEAAGTNSPVAPKQPDARSDLLAQIQSGIKLKKVQRAEAEAAENAALEANNVAAILKRRMDQVMGNDDSSSEEGADDDEWDD
Protein: Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase) (Q02127)
Organism: Homo sapiens (Human)
Function: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:10727948}; Single-pass membrane protein {ECO:0000269|PubMed:10727948}.
Interaction partners:
- Uridine 5'-monophosphate synthase
- Multifunctional protein CAD
- GMP synthase
- Cytochrome b5 reductase 4
- NADH-cytochrome b5 reductase-like
- NADH-cytochrome b5 reductase 1
- NADH-cytochrome b5 reductase 2
- NADH-cytochrome b5 reductase 3
- Dihydrofolate reductase 2, mitochondrial
- Dihydrofolate reductase
Sequence:
MAWRHLKKRAQDAVIILGGGGLLFASYLMATGDERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLPRARFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRR
Protein: GEO07453p1 (RE17611p) (Ribosomal protein L26, isoform A) (Ribosomal protein L26, isoform B) (Ribosomal protein L26, isoform C) (Q9VVU2)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- Large ribosomal subunit protein uL14
- Small ribosomal subunit protein uS7A
- Small ribosomal subunit protein uS10
- Large ribosomal subunit protein uL4
- Small ribosomal subunit protein uS4
- Small ribosomal subunit protein uS13
- Large ribosomal subunit protein eL33
- Large ribosomal subunit protein uL18
- Small ribosomal subunit protein eS17
- Small ribosomal subunit protein uS9
Sequence:
MKQNPFVSSSRRKNRKRHFQAPSHIRRRLMSAPLSKELRQKYNVRSMPIRRDDEVQVIRGHFKGNQVGKVVQAYRKKFVVYVEKIQRENANGTNVYVGIHPSKVLIVKLKLDKDRKAILERRGKGRLAALGKDKGKYTEETAAQPMETA
Protein: Accessory gland protein Acp32CD (O46203)
Organism: Drosophila melanogaster (Fruit fly)
Function: Responsible for physiological and behavioral changes in mated female flies.
Subcellular location: Secreted {ECO:0000305}.
Interaction partners:
- Uncharacterized protein, isoform B
- Accessory gland protein Acp36DE
- ACP53C14A
- Accessory gland-specific peptide 26Aa
- Accessory gland protein Acp53Ea
- Accessory gland protein Acp63F
- Accessory gland-specific peptide 26Ab
- Accessory gland protein Acp62F
- ACP53C14B
- Accessory gland protein Acp29AB
Sequence:
MWRMRMRLLTGYLVLLALGQLPEHGALGQKYYMNFAFNNNNPDGEGGTGVDGGGGGAGGGAAGPGGGTGDSPHSQEGDGSAATDNPNDDHATSADNSLATDGDAIGKKESGGGSDGKSDSKDSSGGNDATPANGHDDDNDDSDSKDAKDRQDKEEEAGQEGKRTDHSHHSSYEISIDDSFGGRYVRSIYESSESHGHSGSNAGSNQRDNGARESSQENQDAKEVASEAPAQRAGNVPDGPETGAKEDDYEEM