wanglab/gogpt-training-data huggingface dataset:
Protein: Zinc finger and BTB domain-containing protein 5 (O15062)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MDFPGHFEQIFQQLNYQRLHGQLCDCVIVVGNRHFKAHRSVLAACSTHFRALFSVAEGDQTMNMIQLDSEVVTAEAFAALIDMMYTSTLMLGESNVMDVLLAASHLHLNSVVKACKHYLTTRTLPMSPPSERVQEQSARMQRSFMLQQLGLSIVSSALNSSQNGEEQPAPMSSSMRSNLDQRTPFPMRRLHKRKQSAEERARQRLRPSIDESAISDVTPENGPSGVHSREEFFSPDSLKIVDNPKADGMTDNQEDSAIMFDQSFGTQEDAQVPSQSDNSAGNMAQLSMASRATQVETSFDQEAAPEKSSFQCENPEVGLGEKEHMRVVVKSEPLSSPEPQDEVSDVTSQAEGSESVEVEGVVVSAEKIDLSPESSDRSFSDPQSSTDRVGDIHILEVTNNLEHKSTFSISNFLNKSRGNNFTANQNNDDNIPNTTSDCRLESEAPYLLSPEAGPAGGPSSAPGSHVENPFSEPADSHFVRPMQEVMGLPCVQTSGYQGGEQFGMDFSRSGLGLHSSFSRVMIGSPRGGASNFPYYRRIAPKMPVVTSVRSSQIPENSTSSQLMMNGATSSFENGHPSQPGPPQLTRASADVLSKCKKALSEHNVLVVEGARKYACKICCKTFLTLTDCKKHIRVHTGEKPYACLKCGKRFSQSSHLYKHSKTTCLRWQSSNLPSTLL
Protein: Putative cyclin-D6-1 (G1/S-specific cyclin-D6-1) (CycD6;1) (Q9ZR04)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Retinoblastoma-related protein 1
- Cyclin-dependent kinase A-1
- Cyclin-dependent kinase B1-1
- Cyclin-dependent kinase B1-2
- Cyclin-dependent kinases regulatory subunit 1
- Cyclin-dependent kinase B2-1
- Cyclin-dependent kinase B2-2
- Ethylene-responsive transcription factor ERF115
- Protein SHORT-ROOT
- Protein SCARECROW
Sequence:
MEFHLEHPLSHSSLHNNFNDDTDYETLPHSLFLVEFQHMPSSHYFHSLKSSAFLLSNRNQAISSITQYSRKFDDPSLTYLAVNYLDRFLSSEDMPQSKPWILKLISLSCVSLSAKMRKPDMSVSDLPVEGEFFDAQMIERMENVILGALKWRMRSVTPFSFLAFFISLFELKEEDPLLLKHSLKSQTSDLTFSLQHDISFLEFKPSVIAGAALLFASFELCPLQFPCFSNRINQCTYVNKDELMECYKAIQERDIIVGENEGSTETAVNVLDQQFSSCESDKSITITASSSPKRRKTSTRRY
Protein: Ras-related protein RABA1c (AtRABA1c) (Q9FK68)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Intracellular vesicle trafficking and protein transport.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Interaction partners:
- Trafficking protein particle complex II-specific subunit 120 homolog
- Trafficking protein particle complex II-specific subunit 130 homolog
- V-type proton ATPase subunit a1
- Syntaxin-61
- Kinesin-like protein KIN-14E
- VAN3-binding protein
- ADP-ribosylation factor GTPase-activating protein AGD3
- Vesicle transport v-SNARE 12
- Tlg2p-like protein a
- Geranylgeranyl transferase type-2 subunit beta 1
Sequence:
MAGYRADDEYDYLFKVVLIGDSGVGKSNLLSRFTKNEFSLESKSTIGVEFATRSLNVDDKVIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDVTRHSTFENVETWLKELRNHTDPNIVVMLVGNKSDLRHLVAVQTEDAKSFAEKESLYFMETSALEATNVENAFAEVLTQIHHIVSKKAMEAASESANVPSKGDKIDIGKDVSAVKKGGCCSN
Protein: Protocadherin alpha 11 (A0A0A6YX38)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Interaction partners:
Sequence:
XNNPPGAHIFTVSAMDADAQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLQFQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPANNQIDKSDFITFGKKEETKKKKKKKKGNKTQEKK
Protein: OFD1 centriole and centriolar satellite protein (A6NF31)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MMAQSNMFTVADVLSQDELRKKLYQTFKDRGILDTLKTQLRNQLIHELMHPVLSGELQPRSISVEGSSLLIGASNSLVADHLQRCGYEYSLSVFFPESGLAKEKVFTMQDLLQLIKINPTSSLYKSLVSGSDKENQKAIKSVT
Protein: ABC-type glutathione-S-conjugate transporter (EC 7.6.2.3) (Q8MQ16)
Organism: Caenorhabditis elegans
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Vacuole membrane {ECO:0000256|ARBA:ARBA00004128}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004128}.
Interaction partners:
Sequence:
MFPLVRELVCGSDYELLETGWRNNSNIPQVTNCGQHTDFSTIPTLFLVIFSPILFYELYKSRNSYLRSFSAISLRIIFCCLLVVDLTATVIYDFYLLFTKSPLYNAIHFYGDLVQYAGFCLALVLTIACRNRGIITSGVITLYWLLVVVCGVPELRYYITGRLYKEYEIHSCRAALYVFAYVCSALELFLSCFADTPSNGYIGKNSCPEYTASFLNQLTFQWFSGLAYLGNKKSLEKEDLWDLNERDKAENIIPSFIENLIPEVEGYRRKIKKNPEAAIPKNHPSILIPIFKTYKFTLLAGGCYKLMFDLLQFVAPELLRQLISFIEDKNQPMWIGVSIALLMFLSSLLQSMILHQYFHEMFRLGMNIRSVLTSAVYTKTLNLSNEARKGKTTGAIVNLMSVDIQRIQDMTTFIMLFWSAPLQILLSLYFLWKLLGVSVLAGFVILILLIPFNSFISVKMRNCQMEQMKFKDERIKMMSEILNGMKVLKLYSWEKSMEKMVLEVREKEIRVLKKLSYLNAATTLSWACAPFLVAVLTFGLYVLWDPENNVLTPQITFVALALFNILRFPLAVFAMVFSQAVQCSASNTRLKEFFAAEEMSPQTSIAYGGTDSAIKMDGGSFAWGSKEEDRKLHDITFNIKRGQLVAIVGRVGSGKSSLLHALLGEMNKLSGSVQVNGSVAYVPQLAWIQNLSLRNNILFNRPYDAKLYQNVIENCALVQDLESLPAEDRTEIGEKGINLSGGQKQRVSLARAVYQNAEIVLLDDPLSAVDSHVGKHIFENVISTATGCLGTKTRVLLTHGLTYLKHCDQVIVLKDETISEMGTYQELMNSNGAFSEFLEEFLLEESKHKGRSVSFGEDSKEVNELLRDLDQVSPAIRQRIQSQMSQEIEKTDDKNAEIIRNGLHKDEQTAHSSIGKSEEKESLLGAISPKEKTPEPPKQTKTQLIEKEAVETGKVKFEVYMSYFRAIGIKIALVFFLVYVASSMLGVFSNLYLARWSDDAKEIALSGNGSSSETQIRLGIYAVLGMGQATSVCAASIIMALGMVCASRLLHATLLENIMRSPMAFFDVTPLGRILNRFGKDIEAIDQTLPHSIRAMVMTIFNVISTVFVIIWATPWAGIGFLVLGFVYFVVLRFYVSTSRQLKRLESASRSPIYSHFQESIQGASSIRAYGVVDKFIRESQHRVDENLATYYPSIVANRWLAVRLEMVGNLIVLSSAGAAVYFRDSPGLSAGLVGLSVSYALNITQTLNWAVRMTSELETNIVAVERINEYTITPTEGNNSQSLAPKSWPENGEISIKNFSVRYRPGLDLVLHGVTAHISPCEKIGIVGRTGAGKSSLTLALFRIIEADGGCIEIDGTNIADLLLEQLRSRLTIVPQDPVLFSGTMRMNLDPFFAFSDDQIWEALRNAHLDSFVKSLQEGLHHHISEGGENLSVGQRQLICLARALLRKTKVLVLDEAAAAVDVETDSLLQKTIREQFKDCTVLTIAHRLNTVMDSDRLLVLDKGCVAEFDTPKKLLSNPDGIFYSMAKDANVV
Protein: Dolichol kinase EVAN (EC 2.7.1.108) (F4J4C8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Essential for pollen development. Involved in protein N-glycosylation in the endoplasmic reticulum (ER), especially in the female gametophyte. Mediates pollen tube (PT) reception in synergids through protein glycosylation.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:25919390}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
- Polyprenal reductase 2
- Dolichol-phosphate mannosyltransferase subunit 1
- Dolichol-phosphate mannose synthase subunit 2
- dolichyl-phosphate beta-glucosyltransferase
- Lipid phosphate phosphatase gamma
- Polyprenal reductase 1
- At3g57220
- UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase
- Dolichol-phosphate mannose synthase subunit 3
- UDP-glycosyltransferase TURAN
Sequence:
MKTTATSFVTGERVVVFVVVSRILLSLPLSLISHGFSLFLLSLSAFLVEIRVETSPFLLSHFSSRRGASSGILLGAVTLPSVMISKLVQLSRAISIHEAEQDELAHVTMQYWAASASCCAILIYLSVIMSQVRKDESLSSSSIWLTRVSLTGTVLYGVACFVSLSMISHTGLNTSLKMLWMLFHGLAAVKLIRHLLCTFPSCASIGEALLVTSGLVLYFGDFLACTIAKIFEKLIPVDLVSISYGIKRTETGIIVQGLLLGLLLFPMVFRFVLHIYESSLRKRDARQRNCSDAAKSVLFFVSLLFFMVVAVPSWMQFVHDFNQHPFLWVLTFVFSEPLKRLSLCIYWILLIVVSVSRFYNISRSSKVERILLRKYYHLMAVLMFLPALVLQPKFLDLAFGAALAVFVALEIIRIWRIQPLGEPLHQFMNAFTDHRDSEHLIVSHFSLLLGCALPIWMSSGFNDRALSPFAGILSLGIGDTMASMVGHKYGVLRWSKTGKKTVEGTAAGITSMMAVCFVLVPILASMGYILSQGWWSLLVAVTATGMLEAYTAQLDNAFIPLVFYSLLCL
Protein: FAD-binding PCMH-type domain-containing protein (Q5BAP3)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Interaction partners:
Sequence:
MRIINAAPLAGFLSLAGLSLATNPNGTYGCAALKKDIPNSLFERNSTVYNDESNNFWSNTEIMSPECVFRPESATELGTAIKLLKRTNTQFAVRGGGHMGIRGSNNIDGGVLIVMSKLNTLELNEDQSILHLGPSHRWGEVYSYLQPYGLAVAGGRLAPVGVPGLLLAGGVNFYGNQVGWGCDTVVNYEVVLADGSVVQVNKTSYPDLFWALKGGSSNFGLVTRFDVETIKSPLVWAGSYTVSEEYIDDFLKAVATFAANISDPKTHIVPALVPIPGSPTVASAILFYDSADTSFPEVFKPFTDIPVYASTLGFKTLADFAEELGQMVVDDINDVFVAGTVKGTTYGELYHGISIINSTFFARLPELYAKVPASAISTIQLDWQPIGKLWLDASAKAGGNPLGLDASKVYLAYAEVVEWTDSQYDEVVMQWVEETTNAINAATKKAGLYDPFNYIGDAAGFQEIFPGYGAENHRRLAKIAQKYDPHAVFQSLMPGGFKVFEN
Protein: 5'-nucleotidase domain-containing protein 3 (EC 3.1.3.-) (GRP94-neighboring nucleotidase) (Q86UY8)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MTMAAAAVVARGAGARAATAAALRGGCGTAARGRPCAGPARPLCTAPGTAPDMKRYLWERYREAKRSTEELVPSIMSNLLNPDAIFSNNEMSLSDIEIYGFDYDYTLVFYSKHLHTLIFNAARDLLINEHRYPAEIRKYEYDPNFAIRGLHYDVQRAVLMKIDAFHYIQLGTVYRGLSVVPDEEVIEMYEGSHVPLEQMSDFYGKSSHGNTMKQFMDIFSLPEMTLLSCVNEYFLKNNIDYEPVHLYKDVKDSIRDVHIKGIMYRAIEADIEKYICYAEQTRAVLAKLADHGKKMFLITNSPSSFVDKGMSYIVGKDWRDLFDVVIVQAEKPNFFNDKRRPFRKMNEKGVLLWDKIHKLQKGQIYKQGNLYEFLKLTGWRGSRVLYFGDHIYSDLADLTLKHGWRTGAIIPELRSELKIMNTEQYIQTMTWLQTLTGLLEQMQVHRDAESQLVLQEWKKERKEMREMTKSFFNAQFGSLFRTDQNPTYFLRRLSRFADIYMASLSCLLNYDVSHTFYPRRTPLQHELPAWSERPPTFGTPLLQEAQAK
Protein: Natural cytotoxicity triggering receptor 1 (Lymphocyte antigen 94 homolog) (NK cell-activating receptor) (Natural killer cell p46-related protein) (NK-p46) (NKp46) (hNKp46) (CD antigen CD335) (O76036)
Organism: Homo sapiens (Human)
Function: Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- High affinity immunoglobulin epsilon receptor subunit gamma
- T-cell surface glycoprotein CD3 zeta chain
- Natural cytotoxicity triggering receptor 2
- Natural cytotoxicity triggering receptor 3
- NKG2-D type II integral membrane protein
- Low affinity immunoglobulin gamma Fc region receptor III-A
- TYRO protein tyrosine kinase-binding protein
- Properdin
- Natural cytotoxicity triggering receptor 3 ligand 1
- Low affinity immunoglobulin gamma Fc region receptor III-B
Sequence:
MSSTLPALLCVGLCLSQRISAQQQTLPKPFIWAEPHFMVPKEKQVTICCQGNYGAVEYQLHFEGSLFAVDRPKPPERINKVQFYIPDMNSRMAGQYSCIYRVGELWSEPSNLLDLVVTEMYDTPTLSVHPGPEVISGEKVTFYCRLDTATSMFLLLKEGRSSHVQRGYGKVQAEFPLGPVTTAHRGTYRCFGSYNNHAWSFPSEPVKLLVTGDIENTSLAPEDPTFPADTWGTYLLTTETGLQKDHALWDHTAQNLLRMGLAFLVLVALVWFLVEDWLSRKRTRERASRASTWEGRRRLNTQTL
Protein: Stress-induced protein KIN2 (Cold-induced protein COR6.6) (P31169)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Protein COLD-REGULATED 15A, chloroplastic
- Low-temperature-induced 78 kDa protein
- Dehydrin COR47
- Protein COLD-REGULATED 15B, chloroplastic
- Dehydrin ERD10
- Dehydration-responsive element-binding protein 1B
- Low-temperature-induced 65 kDa protein
- Dehydration-responsive element-binding protein 1C
- Dehydration-responsive element-binding protein 1A
- Dehydration-responsive element-binding protein 1D
Sequence:
MSETNKNAFQAGQAAGKAEEKSNVLLDKAKDAAAAAGASAQQAGKSISDAAVGGVNFVKDKTGLNK
Protein: Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2) (OGDC-E2) (Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex) (E2K) (E2o) (PE2o) (Q9N0F1)
Organism: Sus scrofa (Pig)
Function: Dihydrolipoamide succinyltransferase (E2) component of the 2-oxoglutarate dehydrogenase complex. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion (By similarity). A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A (By similarity).
Subcellular location: Mitochondrion matrix {ECO:0000305|PubMed:10806400}. Nucleus {ECO:0000250|UniProtKB:P36957}. Note=Mainly localizes in the mitochondrion. A small fraction localizes to the nucleus, where the 2-oxoglutarate dehydrogenase complex is required for histone succinylation. {ECO:0000250|UniProtKB:P36957}.
Interaction partners:
- Dihydrolipoyl dehydrogenase, mitochondrial
- 2-oxoglutarate dehydrogenase complex component E1
- 2-oxoglutarate dehydrogenase-like, mitochondrial
- Succinate--CoA ligase subunit beta, mitochondrial
- 2-oxoadipate dehydrogenase complex component E1
- Succinate--CoA ligase subunit alpha, mitochondrial
- 2-oxoisovalerate dehydrogenase subunit alpha
- 3-methyl-2-oxobutanoate dehydrogenase
- Pyruvate dehydrogenase E1 component subunit beta
- Citrate synthase, mitochondrial
Sequence:
MLSRSRCVSRAFSRSLSAFQKGNCPLGRRSLPGISLCQGPGYPDSRKIVISNSSVLNVRFFRTTAVCKDDVITVKTPAFAESVTEGDVRWEKAVGDTVAEDEVVCEIETDKTSVQVPSPANGVIEALLVPDGGKVEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPAVSAVPPPPAASIPTQMPPVPSPPQPLTSKPVSAVKPTAAPPVAEPGAVKGLRAEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQDMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVYRDYIDISVAVATPRGLVVPVIRNVETMNYADIERTISELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMHAIVDRPVAVGGKVEIRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLLLDL
Protein: LD38414p (Prage, isoform B) (Q8T023)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MEQITNYFEHMDYVSFSVVALPCVVIAVYGFLQVASGLAKCKNDKMQSCNKNSSSRITTTNNNVTTTSNISGNSSNKRCPQKYTGNTLAVNSNMLAYQQQATAGGKNSTRKSRHNNNKQNHQQQQQQQQQQFDHIHKRNGTAGGTGSECSPAAPTSNWLQRGYGRQFVHSSCIEDKLLGHHNPGHRNSTSSDATSEDIDSSSELPNKSKGNSCAGSIHASGGSKSRSKRHQKQSGQQTRNPDHNGQRTGAATPCTGQKAKQGNAKWRQQQPNPSSNNQQQQMQQQMQQQKRGRNKKPGKWSNNIIDNPNSNHGGSSQQKTCDSSSSSALSSPTSSATTSATSSPTNSPTSYPRANGNRKRIEAALEWRREQELGRQNANFLVPPLRQYEQLEFDDKTVVQQLRRHIIDNHLLRVYGFPVDSVVHEGAIEIFKCMPHMSFAAALAETAQAVTVINYHDGLTNRAEEEVANSTDSGNSSPQSLDSESGGEWSGSECESSNSSSSSAGEAALGLELKYCHFVPVERSLSKPCARCKRHFLVDELTGQYLTHEECQYHSGKYQRYYDGVSHGRWTCCNEGEESSPGCCLGDRHVWSGSVVGVNGPYYDFVRTEHRGSGEDEPAVYALDCEMSYTGRGLDVTKVSLVALNGQLVYEHFVRPVCDIIDYNTQYSGITETDLCSGAKSLAEVQRDLLQLITADTILIGHGLENDLRALRLVHNTLIDTSISFPHCNGFPYRRALRHLTKVHLKRDIQAGDGTTGHSSFEDSRACMELMLWRVNRELDPAWSWDD
Protein: Glycine N-acyltransferase-like protein 2 (EC 2.3.1.13) (Acyl-CoA:glycine N-acyltransferase-like protein 2) (Q8WU03)
Organism: Homo sapiens (Human)
Function: Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine. Conjugates numerous substrates, such as arachidonoyl-CoA and saturated medium and long-chain acyl-CoAs ranging from chain-length C8:0-CoA to C18:0-CoA, to form a variety of N-acylglycines. Shows a preference for monounsaturated fatty acid oleoyl-CoA (C18:1-CoA) as an acyl donor. Does not exhibit any activity toward C22:6-CoA and chenodeoxycholoyl-CoA, nor toward serine or alanine.
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:20305126}.
Interaction partners:
Sequence:
MLVLHNSQKLQILYKSLEKSIPESIKVYGAIFNIKDKNPFNMEVLVDAWPDYQIVITRPQKQEMKDDQDHYTNTYHIFTKAPDKLEEVLSYSNVISWEQTLQIQGCQEGLDEAIRKVATSKSVQVDYMKTILFIPELPKKHKTSSNDKMELFEVDDDNKEGNFSNMFLDASHAGLVNEHWAFGKNERSLKYIERCLQDFLGFGVLGPEGQLVSWIVMEQSCELRMGYTVPKYRHQGNMLQIGYHLEKYLSQKEIPFYFHVADNNEKSLQALNNLGFKICPCGWHQWKCTPKKYC
Protein: Two component system response transcriptional positive regulator PhoP (A5U0E5)
Organism: Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
Interaction partners:
Sequence:
MRKGVDLVTAGTPGENTTPEARVLVVDDEANIVELLSVSLKFQGFEVYTATNGAQALDRARETRPDAVILDVMMPGMDGFGVLRRLRADGIDAPALFLTARDSLQDKIAGLTLGGDDYVTKPFSLEEVVARLRVILRRAGKGNKEPRNVRLTFADIELDEETHEVWKAGQPVSLSPTEFTLLRYFVINAGTVLSKPKILDHVWRYDFGGDVNVVESYVLYLRRKIDTGEKRLLHTLRGVGYVLREPR
Protein: Acyl-CoA dehydrogenase family member 11 (ACAD-11) (EC 1.3.8.-) (B3DMA2)
Organism: Rattus norvegicus (Rat)
Function: Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA. Probably participates in beta-oxydation and energy production but could also play a role in the metabolism of specific fatty acids to control fatty acids composition of cellular lipids in brain.
Subcellular location: Peroxisome {ECO:0000269|PubMed:14561759}. Mitochondrion membrane {ECO:0000250|UniProtKB:Q709F0}.
Interaction partners:
- Enoyl-CoA delta isomerase 2
- Hydroxysteroid dehydrogenase-like protein 2
- UBX domain-containing protein 7
- UBX domain-containing protein 7
Sequence:
MEMDVTRDTVEVLPQHKFDIRSLEAYLNQHLPGFGSDHRAVLTVTQYRSGQSNPTFFLQKGSQAYVLRKKPPGSLLPKAHKIDREFKVQKALFSVGFPVPKPLLYCSNASIIGTEFYVMEHVQGRIFRDFSIPGVSPAERAAIYVSLVETLAWLHSLDIHSLGLDRYGTGVGYCKRQVSTWTKQYQASAHQSIPAMDQLSTWLMRNLPDSDNEECLVHGDFKLDNIVFHPKECRVIAVLDWELSTFGHPLSDLAHLSLFYFWPRTLPMINRGSHIQENTGIPLMEELISIYCRRRGIDPNLPNWNFFMALSFFKLAGIAQGVYSRYLMGNNSSEDSFLTANTVQPLAETGLQLSRRTLSTVPPQADAKSRLFAQSRRGQEVLTRVKQFMKQHVFPAEKEVAEYYAQNGNSAEKWEHPLVIEKLKEMAKAEGLWNLFLPAVSGLSQVDYALIAEETGKCFFAPDVFNCQAPDTGNMEVLHLYGSEQQKQQWLEPLLRGDITSVFCMTEPNVSSSDATNMECSIQRDGGSYIVHGKKWWSSGAGNPKCKIAVVLGRTESPSVSRHKVHSMILVPMDTPGVELIRPLSVFGYMDNVHGGHWEVHFNHVRVPASNLILGEGRGFEISQGRLGPGRIHHCMRSVGLAERILQIMCDRAVQREAFGKKLYEHEVVAHWIAKSRIAIEEIRLLTLKAAHSIDTLGSAAARKEIAMIKVAAPKAVCKIADRAIQVHGGAGVSQDYPLANMYAIIRTLRLADGPDEVHLSAIAKMELQDQARQLKARM
Protein: Vacuolar protein sorting-associated protein 4B (EC 3.6.4.6) (Cell migration-inducing gene 1 protein) (Suppressor of K(+) transport growth defect 1) (Protein SKD1) (O75351)
Organism: Homo sapiens (Human)
Function: Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their ATP-dependent disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. VPS4A/B are required for the exosomal release of SDCBP, CD63 and syndecan.
Subcellular location: Late endosome membrane {ECO:0000250|UniProtKB:P46467}; Peripheral membrane protein {ECO:0000305}. Note=Membrane-associated in the prevacuolar endosomal compartment. Localized in HIV-1 particles purified from acutely infected cells. {ECO:0000269|PubMed:14505570}.
Interaction partners:
- Vacuolar protein sorting-associated protein VTA1 homolog
- Charged multivesicular body protein 1a
- Charged multivesicular body protein 2b
- Charged multivesicular body protein 5
- Charged multivesicular body protein 2a
- Charged multivesicular body protein 1b
- Charged multivesicular body protein 6
- IST1 homolog
- Vacuolar protein sorting-associated protein 4A
- Programmed cell death 6-interacting protein
Sequence:
MSSTSPNLQKAIDLASKAAQEDKAGNYEEALQLYQHAVQYFLHVVKYEAQGDKAKQSIRAKCTEYLDRAEKLKEYLKNKEKKAQKPVKEGQPSPADEKGNDSDGEGESDDPEKKKLQNQLQGAIVIERPNVKWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSIIFIDEIDSLCGSRSENESEAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEPHARAAMFKLHLGTTQNSLTEADFRELGRKTDGYSGADISIIVRDALMQPVRKVQSATHFKKVRGPSRADPNHLVDDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVSMSDMLRSLSNTKPTVNEHDLLKLKKFTEDFGQEG
Protein: Leucine-rich repeat, isoform C (E1JGZ8)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
Sequence:
MSTRSQLTKDLNESVKSILGRHTKILVKYMVKLETKGDKTENRVLVFTPVRVYLLSAKVPTKIECHFHYLDIVGVESKKSTHFSIVTNDRPYSFVTTGDAGNFSSNADVILTDLASAIKQIFPTVPLKYIIRKIDIQPPERETIFSEEFRPSDPRNVGPCGGFSAQYACMCDFHGVPYREEVAWDVDTIYLSHDTRVLNLRDFDHLEPKDLMAIVSALEYNTFFRGLKAAHMRLSHETLERILHVLKRSMWLEELHLEALGLRWDFLNKLSISVITNSNPAIRTIDLSHNIIEDKGAIHLAGPIAKVSKGLCKLALAHCGLTSKGVNQMSHSLTLNQSISNSLTYLDLSGNSLKDDITNLHNFLAQPNVLEHLDLASTDITLENLFGALLRGCATHLAHLNVSHNSFSTKKGKEIPPSFKQFFTSTFSLKHLNIAGCKLPMEALKNLLLGLACNESTAGLYLDLSSNTLGAQGAHVLESCIHGVRVLQSLDISDNNLDAELAPVLTAISKNPSIRTLHLTRSLTGMKPKHIPPVMDALVNLIQKDDFPLVELVLSENKLKHDLHDFINALGSNQSLQKLDISGNFMGDVGARLLAKALQINNRLRTIYMDKNGVTLQGYADIVYALEHNHSMRTIPFPVFDIAPHLKSHPDKTDAVMRKMQELLQRNCNGLKRATGQGFRLQHGFMLSSTHQLVDKLVAETQDTISLAKGGSESASAVQRLITDAENCKQLMPKLQEAVRNESHPIEMKMTRVASELSYTIKSYLEETMETMMRTGIEQCPKTLGNQIVVQDLRKALAERLVVPEEFLQICLLNNAGSEIMNKVGEIEQSLAAAISDRATDEVLEALTRYRRGMGIAESPSVLLDEPQTPDIVRSRSSHDADGLIIRPGGRGSILPKLGLESPTATPHLPTKRRSLAKKVRPQSVVENLSLGHFPDLLESPSSHRSNSQLSARAAAGAAALVGAANMTDSIAVDDGGVDECCDSITELPSASFQLQHLVKGRPKRAKTRAPTRPLVTTECAGGSREIGEGLEHFFRPGSVTPTTLTPLVSPTSEECSSLSFVDSPTMSRDGNGHMTSEETTPILEERRPIKLERQSPLLKSASWATRSRSTDNLEKYSPLVGRKSPLVKMRTEGGPGSGSATGAEETSMPSSNLLKATAREDKTRSPSSDSIKSHAAGEGSVIVKTGNGILRTPIVLQKPRPWSVVGSEPKAGGDLITGNGNADSSKTTPDKLEEDDVEIVTFGNTCSGSIVGITPGIALSTSGGGSIVGITPGGALEKKSVRELAAGLNRMELPLKPPVMPRTLLNATSVRTSTSSTGSTSNSVSVSSSTNANTSMTVLNQSQTRSRIVSSTSSTDSTETITERSTTSTSSSSSSSYEKQHAKACANLISNEILSMRNGQLGAKSGSCAESGGVKRIAGKEISTLFEV
Protein: CAP/Srv2p (G-actin binding protein, putative) (Q38A49)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- ADF-H domain-containing protein
- Profilin
- Cofilin/actin depolymerizing factor, putative
- G-actin binding protein, putative
- Uncharacterized protein
Sequence:
MPPPPPAPPPPPPPPPPPKATEGNSSSTVGGAASALFAEIRQGGDNITSRLRHVTDDQKAYKQNIQHGAVDFSDLDAKKAEAEAKRQQKQKQPETTAAEEPVTRLEGDKRWVVKHHKGTPSEPCKVTLEDVNMRHAVHIHGCDNTFVEVKGKVNTVSVVSCNKAQVILESVVSALEVLKSDSVDVTVRRFVPTAMVEKSTSVNLFLMDVEEAPNTEIVTACSSAVNVNFPTVEDPTDILERPLPEQFVSRIVRDNRGKYKIETKPNEVA
Protein: Protein translocase subunit SecA (EC 7.4.2.8) (Q3S2Y3)
Organism: Streptococcus agalactiae
Subcellular location: Cell membrane {ECO:0000256|HAMAP-Rule:MF_01382}; Peripheral membrane protein {ECO:0000256|HAMAP-Rule:MF_01382}; Cytoplasmic side {ECO:0000256|HAMAP-Rule:MF_01382}. Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01382}. Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}. Note=Distribution is 50-50. {ECO:0000256|HAMAP-Rule:MF_01382}.
Interaction partners:
Sequence:
MKKVVVKPKISILNKLRLQRIQKIVNEINNKKVYYAQLSDKELSHQTLILKNRLSSGESLDDILVDAFAVIREANKRILGLFPYDAQVMGAIALHQGTIAEMKTGEGKTLTATMPLYLNALTSKGAILVTTNDYLAKRDALEMGKVYQFLGMTVGINVFDKKEEADATIKREVYESDITYTTAGALGFDYLVHNLASNKLEQFLRPFHFVIVDEADSVLLDIAQTPLIIAGDPRVQSNLYGITNNFVLTLKENDEYIHKAKDKIVYLTEKGVSYAKQYFNISELYNDEYWELNRHINLALRAHCLYKRDYDYVVKNNEVKLLDNATGRVMEGTKLQSGIHQAIEAKEDVALTNESRAIASITYQSLFNMFPRLSGMTGTGKSSEDELIKTYHLPVIVIPTNFPIKRVDLADKIYVSLPEKLQATIDDVKQRHSKGQPVLLISGTVEIANIYSKLLLREGIAHNTLTADNVVKEAQIIKEAGQKGSVTCATVLAGRGTDIKLGEGVRELGGLAVIGTERMPNLRMDWQLRGRSGRQGDPGISQFYVSLEDELIVSHSPEWVIKYLKKYSRKETSNYYMVPRKKRFFYQIVKNAQLRSEDKGVSSREQTIKFGESLRIQRENIYQLRNELIADSSIVVDGVIKIIQDNFNDIANDKDLTEHSLRRYILENLTYKFKYFPDEFDVHNSDDVFKLLIDIFDREFTAKKTKLQSDNEFDNFVRISILKAIDKSWIEEVDSLQQLKGVVTNRGIGQRDIIQEYYKESLNSYYKMGKEIRYSIVKNIMLSTISKASDGSYSIYYV
Protein: Oxidoreductase-protein, putative (Q387R1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MKHDFPKRPREPAPSDCCGSGCTRCVWDVYFDEMMKYEERMQNAVIKDEFADGDVKGGCDSSSDDSDGDGVSSNYVGSVVVKYIDIPNDEGRCVTAATSISTILGRFSDVVDVHTVSSSSRGNSGAHSPVGNQDIHVLDVVLGETDGFEKLKLPLLPLPGDVVEIFRPNDYSVGNCEQPGEVEKLCDRLGVSPNQWCELYRSPFVPTGHFPPWLPLQQPVQIRTLLAYFVDIGSCSYILRPTFLQTLFRVATSVKGVLPDSLTPESRDMLELLKVCGSSEVAPLIYKATVSGNATPCFPRLIDVLNVFSFVNFPLARLLEVSGPLRARKFSVANYTLSETADRQGGSCLGSVQLCLRGVDVAKTESAVEKECTSEPAHIFAGLLRGAALRRCTEGGNGGNHFTGHVSNPLCYFHSRQHALRLYVGTKLFGMSSFAKNLNRAITPVRLSTGLSPVPTMLPWVILVGAGTGIAPLMSAVNELVRRRADGSAVERCSTKCWVVYGARNFSELVYHEQLQEALRLGAISRYEVALSRSTAGEHPRYVTDVLESHAEFIRSELLERSGWMFACGPLSAMRSLRERMTAKILRAADDDESVSEQRIRYLEGTEHLVFDIWGSVGLFS
Protein: F-box protein PP2-B1 (Protein PHLOEM PROTEIN 2-LIKE B1) (AtPP2-B1) (SKP1-interacting partner 21) (Q6NPT8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
Subcellular location: Nucleus {ECO:0000250}.
Interaction partners:
- Protein PHLOEM PROTEIN 2-LIKE A2
- Protein PHLOEM PROTEIN 2-LIKE A9
- Immune-associated nucleotide-binding protein 10
Sequence:
MEQIHGGDSNSGGGGGGSSRNDEISVTRASRFDALPEDCISKVISHTSPRDACVVASVSKSVKSAAQSDLVWEMFLPSEYSSLVLQSANHLSKKEIFLSLADNSVLVENGKKSFWVEKASGKKCYMLSAMELTIIWGDSPAYWKWITVPESKFEKVAELRNVCWFEVRGKISCGMLSKGTHYSVYVVFKTANGRSYGFDLVPVEAGVGFVGKVATKKSVYFESGNADSRSATSHYSGISYAMVSRAFRMRRPWMQVQREEEEEVEGERERGMNVVGPKERVDGWSEVELGKFYINNGGCGDDGSDEIEISIMETQNGNWKSGLIIQGIEIRPERSN
Protein: Ethylene-responsive transcription factor ERF087 (Q9FZ90)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
Sequence:
MEFNGNLNAGSCSRSKKSHRQKQQQPQPQPQQHIEEIKYVGVRRRPWGRYAAEIRNPTTKERYWLGTFDTAEEAALAYDRAARSIRGLTARTNFVYSDMPRGSSVTSFVSPDESQRFISELFNPPSQLEATNSNNNNNNNLYSSTNNQNQNSIEFSYNGWPQEAECGYQSITSNAEHCDHELPPLPPSTCFGAELRIPETDSYWNVAHASIDTFAFELDGFVDQNSLGQSGTEGFNSLPSTFFYQ