wanglab/gogpt-training-data huggingface dataset:
Protein: Spalt-like protein sem-4 (Sex muscle abnormal protein sem-4) (Transcription factor sem-4) (G5EFF4)
Organism: Caenorhabditis elegans
Function: Transcription factor, involved in positive and negative modulation of transcription. Binds to multiple DNA sequence motifs in the regulatory elements of target genes, including homeobox selector egl-5 and LIM homeobox mec-3. Involved in cell-fate regulation in multiple lineages, including neuronal, mesodermal and vulval. Required to regulate the fate of PLM touch receptor neurons, acting via negative modulation of transcription of egl-5 and mec-3. May modulate gene expression by interacting with different transcription factors during neuronal and mesodermal cell development. Promotes the proliferative sex myoblast (SM) fate, in a cell autonomous manner, acting via the SoxC transcription factor sem-2. Involved in vulval cell-fate determination, acting by regulating expression of homeobox protein lin-39, and may link lin-39 to incoming signaling pathways. Plays a role in detoxification of reactive oxygen species (ROS), by regulating expression of transcription factor skn-1 and the phase II detoxification genes.
Subcellular location: Nucleus {ECO:0000305}.
Interaction partners:
- Homeobox protein ceh-6
- Egg-laying defective protein 27
- Homeobox protein egl-5
- Transcription factor egl-46
- Probable histone-binding protein lin-53
- Transcription factor sox-2
- Probable histone-binding protein rba-1
Sequence:
MNELLAEMAAVSSRRKQSKPRRMSGEGDAMMSPIDLSTKSFDENNCEKGAGGALPLEDRSNILPHFSVPFANPQQFLSLCAQLGNSSSRNVSSTASTTSSCPIQSCSQSFSSPAALTWHVLDAHEDEQEIFSCDVCTTTFSNGQDIREHKCQKTLASRSTSVPPSTIPSSVCFLSTPTTPCLQFSINESIGTSEIREEDEEEDMDVEDGEHVANQLFGHLLQKSDDKSKMASLFNHAFPPFAAFPNMPPPFLMRQPFDPRADVFAAGRHDNDDDWEALMEISTSDEAEKIRALVGDKAVPTTDPNQCILCRRVLSCKSALQMHYRTHTGERPFKCKICQRAFTTKGNLKTHMGVHRSKHSFRGLPISLPPQLAAMHQHQHQIAPPQRIHIHNPPTSAASAAAAVAQIQASQQCPICQQRFLNAGELAVHITEHRNSLTQPPRVMPTPTTTRVQTFPFVPFFTTPPSLNATDMSTQFNLANILSAQLKNDSSPNTDTSSVEEKITRDDPPKMASLSPSNSSDSSSSVRQDILESSEFEEKLKKLEEPPILEQQVSTTPNPKNENPLLAMQKMWAETEPPPPRQMPVLSKHQCGVCFKHFSSSSALQIHMRTHTGDKPFKCDMCGRAFTTRGNLKVHMGTHSWQQSPSRRGRRIFDVASSVTEKPMLQSPILPTSGAPGASPLAMLGPNGLSGLEMMMMLWRTVCSVCQKVCQSPNELEQHLKEHLNNGSSAAPTPLASAATPPPS
Protein: Moesin/ezrin/radixin homolog 1 (G5EES2)
Organism: Caenorhabditis elegans
Subcellular location: Cell junction, adherens junction {ECO:0000256|ARBA:ARBA00004536}. Cell membrane {ECO:0000256|ARBA:ARBA00004202}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}. Cell projection, microvillus {ECO:0000256|ARBA:ARBA00004105}. Cell projection, rhabdomere {ECO:0000256|ARBA:ARBA00043944}.
Interaction partners:
Sequence:
MSKKAINVRVTSMDSELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYTDNKGFPTWLKLNKKVLSQDVKKDPTLVFKFRAKFYPEDVAEEIIQDVTMRLFYLQVKDGILSDEIYCPPETSVLLASYAMQAKYGDYVPETHVAGCLTADRLLPQRVLGQFKLNSEEWERRIMTWWADHRATTREQAMLEYLKIAQDLEMYGVNYFEIRNKKGTDLYLGVDALGLNIYDKADRLSPKVGFPWSEIRNISFNDKKFVIKPIDKKAHDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKQQAREDRALKIAEQEKLTREMSAREEAEQRQRDAEKRMAQMQEDMERARLELAEAHNTIHSLEAQLKQLQLAKQALEQKEYELRELTAQLQSEKAMSDGERRHLRDQVDAREREVFSMREEVERQTTVTRQLQTQIHSQQHTQHYSNSHHVSNGHAHDETATDDEDNGATELTNDADQNVPQHELERVTAAEKNIQIKNKLDMLTRELDSVKDQNAVTDYDVLHMENKKAGRDKYKTLRQIRGGNTKRRIDQYENM
Protein: Palmitoyltransferase (EC 2.3.1.225) (Q9VQK9)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000256|ARBA:ARBA00004166}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004166}.
Interaction partners:
- Beta1,4-N-acetylgalactosaminyltransferase B
- Palmitoyltransferase
- Palmitoyltransferase
- Beta1,4-N-acetylgalactosaminyltransferase A
- Palmitoyltransferase
- Palmitoyltransferase
- Palmitoyltransferase
Sequence:
MFLMTAGTSNFLSAAWRSEAEESKSKENGSLCCCEYVAEDSRERSHILGCCCNCVDFDLVCTRLVTCRAIDRRNIDGMLIAFQDRLRLPWRGGAKRISPAAVAPAFIVPLMLGLATLNSKTAIVLMLTLVGFTIWGMELAKRTATRTNFFLSWLVFSVFYMIIIFEFQVPLLELAPEENYALMFFSCAALYCLYSAKALSPLNLVSAQYGTTPKDELPGIAEASSGEEQAEAQTTLQMESVLSLDDDEVGDMDTAERSGLMHGQPNICEICRKVTPRRAYHCPVCGTCVKRRDHHSYWLNCCIGERNYVWYIVGLALSEIALLLGANLTLTSICHPFMVVRPLGYPVLLPDDCSEVFEGFDLGISFVVACYALLISSYIAFILARQAYLWWKGSTLHEYKRTSNAAGRNRIWSNWRAILK
Protein: DNA polymerase-transactivated protein 6, isoform CRA_b (Spermatogenesis associated serine rich 2 like) (B8ZZZ7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDSANEKPALIPREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRTPCSSLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQTMPANKQNGSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFRPKNKGGAKNQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRIEVSTDAAVLSVPAVTLVA
Protein: Amino acid transporter AVT1C (AtAvt1C) (F4IUW3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Interaction partners:
Sequence:
MNHVPSDQSFYIESEDEDDRKDYVEEDGGSHSDSSDDVYDENQAHIKPSSYTTAWPQSYRQSIDLYSSVPSPGIGFLGNNSMTRFGSSFLSSGLIRRHTPESLPTVTKPLLEEQADEQALPKHRLSSQGLLSPIPSRRGSMRKDEKSSMVSHEIPMSRNSSYGQAVLNGLNVLCGVGILSTPYAAKEGGWLGLMILFVYGLLSFYTGILLRYCLDSESDLETYPDIGQAAFGTTGRIFVSIVLYLELYACCVEYIILESDNLSSLYPNAALSIGGFQLDARHLFALLTTLAVLPTVWLRDLSVLSYISAGGVIASVLVVLCLFWIGLVDEVGIHSKGTTLNLSTLPVAIGLYGYCYSGHAVFPNIYTSMAKPSQYPAVLLTCFGICTLMYAGVAVMGYTMFGESTQSQFTLNLPQDLIATKIAVWTTVVNPFTKYALTISPVAMSLEELIPSRHIRSHWYAIGIRTLLVFSTLLVGLAIPFFGLVMSLIGSLLTMLVTLILPPACFLSIVRRKVTPTQMMLCVLIIIVGAISSVIGSYSALSKIVEKLTN
Protein: Catabolite control protein A (Glucose-resistance amylase regulator) (P25144)
Organism: Bacillus subtilis (strain 168)
Function: Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions. Interacts with either P-Ser-HPr or P-Ser-Crh, leading to the formation of a complex that binds to DNA at the catabolite-response elements (cre). Binding to DNA allows activation or repression of many different genes and operons.
Interaction partners:
- Phosphocarrier protein HPr
- Global transcriptional regulator CodY
- DNA-binding transcriptional repressor ScoC
- HPr-like protein Crh
- HPr kinase/phosphorylase
- Acetate kinase
- Transcriptional repressor CcpN
- Citrate synthase 2
- Phosphoenolpyruvate-protein phosphotransferase
- Glyceraldehyde-3-phosphate dehydrogenase 1
Sequence:
MSNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTTTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAIDYEQAIYDAVKLLVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVAMRLLTKLMNKEPVEEHIVELPHRIELRKSTKS
Protein: Tetraspanin-36 (Tetraspanin-3c) (Q6NWG0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Plays a role in migration and segregation of pigment cells (melanophores and xanthophores). Contributes to pigment stripe patterning in the epidermis.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:24734316}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:24734316}; Multi-pass membrane protein {ECO:0000255}. Note=Mainly found in the Golgi apparatus. {ECO:0000269|PubMed:24734316}.
Interaction partners:
- Aerolysin-like
- Aerolysin-like
- Jacalin 4
- Natterin-like
- Aerolysin-like protein
- Aerolysin-like protein
- Myosin VAb
Sequence:
MDCGIITSKTILLLLSLIFWAAGAALAYVGSYVIKSYNNFEDFMSDRHTLIPAAIIIGVAVVMFIIGFVGCCATLRESKVGLGLFLIIIMLIFAAEVTAFVFGIIYRGRIRGDLEKSMNDVFLKYDGLNSETHAVDYLQSQLECCGVKNQTDWTLTSWFAQHNNTVPQSCCKANMTQCTGQLSQPDLLNTQGCEAKLEQVLQDVLSYAMLVILGFAIIKFFGMLSVCVITCKSKKNEYQPLYA
Protein: Butyrophilin-like protein 3 (Butyrophilin-like receptor) (Q6UXE8)
Organism: Homo sapiens (Human)
Subcellular location: Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Interaction partners:
- Xanthine dehydrogenase/oxidase
- Perilipin-2
- Lactadherin
Sequence:
MAFVLILVLSFYELVSGQWQVTGPGKFVQALVGEDAVFSCSLFPETSAEAMEVRFFRNQFHAVVHLYRDGEDWESKQMPQYRGRTEFVKDSIAGGRVSLRLKNITPSDIGLYGCWFSSQIYDEEATWELRVAALGSLPLISIVGYVDGGIQLLCLSSGWFPQPTAKWKGPQGQDLSSDSRANADGYSLYDVEISIIVQENAGSILCSIHLAEQSHEVESKVLIGETFFQPSPWRLASILLGLLCGALCGVVMGMIIVFFKSKGKIQAELDWRRKHGQAELRDARKHAVEVTLDPETAHPKLCVSDLKTVTHRKAPQEVPHSEKRFTRKSVVASQGFQAGKHYWEVDVGQNVGWYVGVCRDDVDRGKNNVTLSPNNGYWVLRLTTEHLYFTFNPHFISLPPSTPPTRVGVFLDYEGGTISFFNTNDQSLIYTLLTCQFEGLLRPYIQHAMYDEEKGTPIFICPVSWG
Protein: Uncharacterized protein (Q57Z48)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- Uncharacterized protein
Sequence:
MRIFVVFLVLAGAFAIQAKTWNAKFPGKGRPPAQTEEEHQKEHCEFLEEVMENYVDGSDDPDGFCDRMPGPDVSNFTCKCRIDGQEKEVLPLCRYLKNCTISVNQTNYTCDVEDSDRVKCVQQIRTQPPQVGKAEGEASPTQNNEEIKAAPEEKPKTDREEESVVHGNDNVTDQKKGDDRSNENAEAIPRNEDNKKVADNGGNGVNDKHNETTTEGDDTRNKLQLPHRNQSLPQAQEKKNNTNHSTSQNDKQNETTEPPPENSATPEAHGVDRPTQDGGIKSPLPLLIIKIYFTAVSFLLLSIF
Protein: Hyaluronan-binding protein 2 (EC 3.4.21.-) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) (Hepatocyte growth factor activator-like protein) (Plasma hyaluronan-binding protein) [Cleaved into: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form] (Q14520)
Organism: Homo sapiens (Human)
Function: Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form. Activates coagulation factor VII. May function as a tumor suppressor negatively regulating cell proliferation and cell migration.
Subcellular location: Secreted {ECO:0000269|PubMed:8827452}. Note=Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.
Interaction partners:
- Fibrinogen beta chain
- WD repeat-containing protein 90
- Fibrinogen gamma chain
- Fibrinogen alpha chain
- Heparin cofactor 2
- A-type potassium channel modulatory protein KCNIP1
- Histidine-rich glycoprotein
- Inactive tyrosine-protein kinase 7
- Plasminogen activator inhibitor 1
Sequence:
MFARMSDLHVLLLMALVGKTACGFSLMSLLESLDPDWTPDQYDYSYEDYNQEENTSSTLTHAENPDWYYTEDQADPCQPNPCEHGGDCLVHGSTFTCSCLAPFSGNKCQKVQNTCKDNPCGRGQCLITQSPPYYRCVCKHPYTGPSCSQVVPVCRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEIGSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDADEKPWCFIKVTNDKVKWEYCDVSACSAQDVAYPEESPTEPSTKLPGFDSCGKTEIAERKIKRIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCTDIKTRHLKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGHCALESKYVKTVCLPDGSFPSGSECHISGWGVTETGKGSRQLLDAKVKLIANTLCNSRQLYDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECGKRPGVYTQVTKFLNWIKATIKSESGF
Protein: ADP-ribosylation factor-like protein 8B (EC 3.6.5.2) (B4E1J8)
Organism: Homo sapiens (Human)
Subcellular location: Cytolytic granule membrane {ECO:0000256|ARBA:ARBA00037807}. Cytoplasm, cytoskeleton, spindle {ECO:0000256|ARBA:ARBA00004186}. Early endosome membrane {ECO:0000256|ARBA:ARBA00004146}. Late endosome membrane {ECO:0000256|ARBA:ARBA00004414}.
Interaction partners:
Sequence:
MIRSASWVWLLPPAGVRPCRAGAPRSRWRVRAEARSCGSRPSSRPFSLPAAIMLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVTKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQHSKSRRS
Protein: Bacterioferritin-associated ferredoxin (Bfd) (Q9HY80)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Bacterioferritin BfrB
- Bacterial ferritin
- Ferredoxin--NADP reductase
- Protein TonB
Sequence:
MYVCLCQGVTDNQIRDAIYEGCCSYREVREATGVGTQCGKCACLAKQVVRETLNDLQSAQPVPAFGTTAFVAA
Protein: [Ribosomal protein bS18]-alanine N-acetyltransferase (EC 2.3.1.266) (KAT) (Peptidyl-lysine N-acetyltransferase) (EC 2.3.1.-) (P0A944)
Organism: Escherichia coli (strain K12)
Function: Acetylates the N-terminal alanine of ribosomal protein S18. Also acts as a N-epsilon-lysine acetyltransferase that catalyzes acetylation of several proteins.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_02210, ECO:0000305}.
Interaction partners:
- DNA polymerase III subunit psi
- tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
- Peptidyl-lysine N-acetyltransferase YjaB
- [Ribosomal protein uS5]-alanine N-acetyltransferase
- Ribosomal-protein-serine acetyltransferase
- Pyrimidine 5'-nucleotidase YjjG
- Peptidyl-lysine N-acetyltransferase YiaC
- Aminoalkylphosphonate N-acetyltransferase
- Peptidyl-lysine N-acetyltransferase PatZ
- Protein ElaA
Sequence:
MNTISSLETTDLPAAYHIEQRAHAFPWSEKTFASNQGERYLNFQLTQNGKMAAFAITQVVLDEATLFNIAVDPDYQRQGLGRALLEHLIDELEKRGVATLWLEVRASNAAAIALYESLGFNEATIRRNYYPTTDGREDAIIMALPISM
Protein: Histone H2A (Q6CK59)
Organism: Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
Function: Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular location: Nucleus {ECO:0000305|PubMed:32004465}. Chromosome {ECO:0000305|PubMed:32004465}.
Interaction partners:
- Histone H4
- Histone H3
- Ubiquitin-ribosomal protein eS31 fusion protein
- Histone H2B.1
- FACT complex subunit SPT16
- Histone H2A.Z
- Histone H2B.2
- Polyubiquitin
- Histone-lysine N-methyltransferase, H3 lysine-36 specific
- Histone-lysine N-methyltransferase, H3 lysine-4 specific
Sequence:
MSGKGGKAGSAAKASQSRSAKAGLTFPVGRVHRLLRKGNYAQRIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIHQNLLPKKSSKAKASQEL
Protein: Nuclear transport factor 2 (NTF-2) (Q57W07)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU369002}. Nucleus {ECO:0000256|RuleBase:RU369002}.
Interaction partners:
- GTP-binding nuclear protein
- DNA repair protein, putative
- MPN domain-containing protein
- Ribosomal protein
- DNA repair protein, putative
- Nucleoporin NSP1-like C-terminal domain-containing protein
- Nucleoporin
- NTF2-related export protein
- Crossover junction endonuclease MUS81
- Nucleoporin
Sequence:
MSFQEIGTGFIRQYYEFFSKNRTQLAGVYRPTSLMTWVGEQIQGGENIMARFANLSFDEALFKTEDIDCHPSLSGGVLVVVNGEVLLKGESHPLKFNDVFHLAQEGSQWYISNQIFRIVGGGGH
Protein: 8-amino-7-oxononanoate synthase (AONS) (EC 2.3.1.47) (7-keto-8-amino-pelargonic acid synthase) (7-KAP synthase) (KAPA synthase) (8-amino-7-ketopelargonate synthase) (C8V1D1)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: 8-amino-7-oxononanoate synthase; part of the cluster involved in the biosynthesis of biotin (also known as vitamin B8 or vitamin H), a water-soluble vitamin that functions as a prosthetic group of many carboxylases, such as acetyl-CoA carboxylase and pyruvate carboxylase. Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON) (By similarity).
Interaction partners:
- Bifunctional dethiobiotin synthetase/adenosylmethionine-8-amino-7-oxononanoate aminotransferase
- 3-ketodihydrosphingosine reductase tsc10
- Biotin synthase, mitochondrial
- Multifunctional tryptophan biosynthesis protein
- Delta-aminolevulinic acid dehydratase
Sequence:
MGDSPKCLRDSLREALRRREDKLCRRKLTILPSSSVDFSSNDFLSLSTSPAYRARFLDILQQAPPLHPFASGGSRLLDGNSAYAEELENFIAAFHNAPSGLLFNSGYDANVGVFSSIPQPGDLIVYDELIHASAHEGMRLSRAGKRIKFPHSSPDGLRAVLQAEITADPRLLQGRRNVFIAFESVYSMDGDVAPIREFVEIVDQLLPYGNGYFLVDEAHATGVFGPRGSGVVQELGLEDRMFVRVHTFGKALASHGAIVLCCADTRDYLINYARSLIYTTALGFPFLASIRAAYELLVEGKTEQLQHKLGQLIAHFRTGLDNLNHKDSSTFEVEHFTNSPIFSLRSSVPRVLASVCQEQGYTVRAIMPPTVPAGKERVRVCLHAGNTVEEVDGLLETIATWLQRMEKQKARL
Protein: Nuclear receptor subfamily 4 group A member 2 (F1R8N1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU004334}.
Interaction partners:
Sequence:
MPCVQAQYGPPPHGSSYSAQSFGYHGDYSADLMATDYTKCELSGGEISAAAATTSLPSFNVFVEGGFEPKPSCLYQLPPQRPIIKKEEESFPPMAPSDEAIPGSSMYFKQSPPSTPPTPLHPGPPSSSFLWDEHSLPPVPQPCLIEGPLKSPRFPHFYEQTVPPSTSGYDTAIGLPLRPERSPSSSSSSSHVPPNMDTHAHSHVHSHTHSNMYPINMGKPGGLAFRSLGMGHCPPLLGESLPSPPNRTSSGEGTCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLASKNCPVDKRRRNRCQYCRFQKCLSVGMVKEVVRTDNLKGRRGRLPSKPKSPLQPEPSPPSPPLSLLNALVRAYSQSTPRELDYSQVTDAVEPVGLSESQQIQMFYRVLTGSMEVTRCWAERLPGFSELHHDDQNMLIDSAFLELFVLRLANRSLLVDEKFVFCTGLVLHRLQCLRGFGEWLDSIRDFSAHLQELNLDMPAFSCLCALVLLTEQCPGLKEPKKVEELQSKLICCLRDHLNSINAGGVASTGKAPPPVGAVLGLRAELRSQRTQGLQRIFYLKLEDLVPPPPLIDRFLDTLPY
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Aurora/IPL1-related kinase 1) (Serine/threonine-protein kinase aurora-A) (Q6DBZ4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm, cytoskeleton, spindle {ECO:0000256|ARBA:ARBA00004186}.
Interaction partners:
Sequence:
MDSGARSKSSRDLKIHRPENEKVSAAGPKRVPVTQSVQKPVSNPHTRVLGAAQGPQRVQRPVGKTSCPGDQNTRPEQHKPAAHSKPQPKPPLSAETNKTAEPSKQDKPHQTPSSTTSTSSNTSGSSKSSKKAWTLENFDIGRALGKGKFGSVYLAREQQTKFILALKVLFKKQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDAARVYLILEFAPKGELYGELQRCGTFDDQRSATYIMELADALRYCHSKAVIHRDIKPENLLLGANGELKIADFGWSVHTPSSRRSTLCGTLDYLPPEMIEGKTHDEKVDLWSLGVLCYEFLVGRPPFETKSHEETYRKISRVEFTYPAHVSNGSRDLINRLLKHNPMHRLPIQGVMEHPWVVENSTKKPTTYTATANN
Protein: T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Chaperonin CCT4) (Q9LV21)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- T-complex protein 1 subunit zeta 1
- TCP-1/cpn60 chaperonin family protein
- T-complex protein 1 subunit alpha
- T-complex protein 1 subunit eta
- T-complex protein 1 subunit gamma
- T-complex protein 1 subunit zeta 2
- T-complex protein 1 subunit epsilon
- T-complex protein 1 subunit beta
- T-complex protein 1 subunit theta
- ATP binding protein
Sequence:
MAAVAAPMASKPRGSKAESFVDNKRREDIRFANINSARAVSDAVRTSLGPKGMDKMISTANGEVIITNDGATILNKMEVLQPAAKMLVELSKSQDSAAGDGTTTVVVIAGALLKECQSLLTNGIHPTVISDSLHKACGKAIDILTAMAVPVELTDRDSLVKSASTSLNSKVVSQYSTLLAPLAVDAVLSVIDPEKPEIVDLRDIKIVKKLGGTVDDTHTVKGLVFDKKVSRAAGGPTRVENAKIAVIQFQISPPKTDIEQSIVVSDYTQMDRILKEERNYILGMIKKIKATGCNVLLIQKSILRDAVTDLSLHYLAKAKIMVIKDVERDEIEFVTKTLNCLPIANIEHFRAEKLGHADLVEEASLGDGKILKITGIKDMGRTTSVLVRGSNQLVLDEAERSLHDALCVVRCLVSKRFLIAGGGAPEIELSRQLGAWAKVLHGMEGYCVKSFAEALEVIPYTLAENAGLNPIAIVTELRNKHAQGEINAGINVRKGQITNILEENVVQPLLVSTSAITLATECVRMILKIDDIVTVR
Protein: BBG-LP15 (Q15K28)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MELLSSNTGTTTTTTTATHHLHQATTTKQLLVQDYLSYASPPTYSRLPPDGHEFPPNFSEPLIMHSHPLKVTTELSYEIQKGGKDESSAPPLPKTGPPATVPRKVYRQDLVINVEPAPSLTRDYQRSLSGGTPRKPSDWRKDEKSEKSVRDKIAMFSSNNELDAIPPAPATAPISSSFTRKPLNRSSENLLDSCSSSSAPSLKTRA
Protein: Armadillo repeat-containing protein 1 (Q9NVT9)
Organism: Homo sapiens (Human)
Function: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:31644573}. Mitochondrion {ECO:0000269|PubMed:31644573}. Mitochondrion outer membrane {ECO:0000269|PubMed:31644573}. Note=Associates with the outer mitochondrion membrane, most likely through its C-terminus (PubMed:31644573). Not integrated into the mitochondrial outer membrane (PubMed:31644573). {ECO:0000269|PubMed:31644573}.
Interaction partners:
- DnaJ homolog subfamily C member 11
- Mitochondrial fission regulator 1-like
Sequence:
MNSSTSTMSEEPDALSVVNQLRDLAADPLNRRAIVQDQGCLPGLILFMDHPNPPVVHSALLALRYLAECRANREKMKGELGMMLSLQNVIQKTTTPGETKLLASEIYDILQSSNMADGDSFNEMNSRRRKAQFFLGTTNKRAKTVVLHIDGLDDTSRRNLCEEALLKIKGVISFTFQMAVQRCVVRIRSDLKAEALASAIASTKVMKAQQVVKSESGEEMLVPFQDTPVEVEQNTELPDYLPEDESPTKEQDKAVSRVGSHPEGGASWLSTAANFLSRSFYW
Protein: Acetylcholine receptor subunit gamma (P02714)
Organism: Tetronarce californica (Pacific electric ray) (Torpedo californica)
Function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular location: Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MVLTLLLIICLALEVRSENEEGRLIEKLLGDYDKRIIPAKTLDHIIDVTLKLTLTNLISLNEKEEALTTNVWIEIQWNDYRLSWNTSEYEGIDLVRIPSELLWLPDVVLENNVDGQFEVAYYANVLVYNDGSMYWLPPAIYRSTCPIAVTYFPFDWQNCSLVFRSQTYNAHEVNLQLSAEEGEAVEWIHIDPEDFTENGEWTIRHRPAKKNYNWQLTKDDTDFQEIIFFLIIQRKPLFYIINIIAPCVLISSLVVLVYFLPAQAGGQKCTLSISVLLAQTIFLFLIAQKVPETSLNVPLIGKYLIFVMFVSMLIVMNCVIVLNVSLRTPNTHSLSEKIKHLFLGFLPKYLGMQLEPSEETPEKPQPRRRSSFGIMIKAEEYILKKPRSELMFEEQKDRHGLKRVNKMTSDIDIGTTVDLYKDLANFAPEIKSCVEACNFIAKSTKEQNDSGSENENWVLIGKVIDKACFWIALLLFSIGTLAIFLTGHFNQVPEFPFPGDPRKYVP
Protein: COP9 signalosome complex subunit 6a (AtCSN6a) (Signalosome subunit 6a) (Q8W206)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. It is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes. The complex is also required for degradation of PSIAA6 by regulating the activity of the Ubl ligase SCF-TIR complex. Essential for the structural integrity of the CSN holocomplex.
Subcellular location: Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}.
Interaction partners:
- COP9 signalosome complex subunit 2
- COP9 signalosome complex subunit 1
- COP9 signalosome complex subunit 5b
- COP9 signalosome complex subunit 8
- COP9 signalosome complex subunit 3
- COP9 signalosome complex subunit 5a
- COP9 signalosome complex subunit 4
- COP9 signalosome complex subunit 7
- COP9 signalosome complex-related / CSN complex-like protein
- NEDD8-like protein RUB3
Sequence:
MAPSSSSGLTFKLHPLVIVNISDHYTRVKTQLNPPASICASGHGSNNGEAMFQQNPRVYGCVIGVQRGRTVEIFNSFELLYDPSTQTLDRSFLEKKQELYKKVFPDFYILGWYSTGSDAEESDMHIHKALMDINESPVYVLLNPAINHTQKDLPVTIYESELHVIDGIPQLIFAHTSYTIETVEAERISVDHVAHLKPSDGGSAATQLAAHLTGIHSAIKMLNSRIRVLYQNLAAMQKGDKSCDNSVLRQVSSLLRRLPAMESERFQDNFLMEYNDKLLITYLAMITNCSSNMNEMVDKFNTAYDRNTRRGGRTAFM