wanglab/gogpt-training-data huggingface dataset:
Protein: Oryzalexin D synthase (EC 1.14.14.112) (EC 1.14.14.123) (Cytochrome P450 76M8) (Ent-cassadiene C11-alpha-hydroxylase 2) (Q6YTF1)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Enzyme of the diterpenoid metabolism involved in the biosynthesis of both phytocassane and the oryzalexin class of phytoalexins. Can hydroxylate syn-pimaradiene, ent-pimaradiene, ent-sandaracopimaradiene, ent-isokaurene, ent-kaurene, and ent-cassadiene, but no activity with syn-stemodene, syn-stemarene, syn-labdatriene, C11-alpha-hydroxy-ent-cassadiene or syn-pimadien-19-oic acid as substrates. Hydroxylates 3-alpha-hydroxy-ent-sandaracopimaradiene at C-7-beta, resulting in a 3-alpha,7-beta-diol corresponding to oryzalexins D.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Interaction partners:
- Probable 5'-adenylylsulfate reductase 1, chloroplastic
- Nitrate reductase
- Nitrate reductase 1
- Nitrate reductase
- 4-coumarate--CoA ligase
Sequence:
MENSQMWLLWGALSVALFFYFSTLRRRYAGGKPLPPGPTPLPLIGNLHLVGGGTFHHKLRDLARVHGPVMTLKLGLATNVVISSREAAIEAYTKYDRHLAARATPDTFRACGFADRSMVFIPSSDPQWKALRGIHASHVFTPRVLAAVRPIRERKVGDLIAYLRAHAGEEVLVGHAMYTGILNMVSFSYFSVDIVDMGSQMARELREVVDDIILVVGKPNVSDFYPFLRPLDLQGLRRWTTKRFNRVFSIMGDIIDRRLAHIRDNKPRHDDFLDSILELMAAGKIDRVNVLNMLFEAFVAGADTMALTLEWVMAELLKNPSVMAKARAELRDVLGDKEIVEEADAARLPYLQAVLKEAMRLHPVGALLLPHFAMEDGVEVGGYAVPKGSTVLFNAWAIMRDAAAWERPDEFVPERFVERTPQLDFRGKDVEFMPFGSGRRLCPGLPLAERVVPFILASMLHTFEWELPGGMTAEELDVSEKFKTANVLAVPLKAVPVLIK
Protein: Small ribosomal subunit protein mS79 (rPPR3b) (Pentatricopeptide repeat-containing protein At3g13160, mitochondrial) (Q9LK57)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14671022}.
Interaction partners:
- Pentatricopeptide repeat-containing protein At1g02370
- Tetratricopeptide repeat
- H/ACA ribonucleoprotein complex non-core subunit NAF1
- Pentatricopeptide repeat-containing protein At1g06270
- Nuclear pore complex protein NUP155
Sequence:
MSSLSRFLLRGNFSFSTHTNRRFFSAVTAAAATPSPPKPSLITLVNDERDPKFITEKFKKACQAEWFRKNIAVYERTVRRLAAAKKFEWVEEILEEQNKYPNMSKEGFVARIINLYGRVGMFENAQKVFDEMPERNCKRTALSFNALLNACVNSKKFDLVEGIFKELPGKLSIEPDVASYNTLIKGLCGKGSFTEAVALIDEIENKGLKPDHITFNILLHESYTKGKFEEGEQIWARMVEKNVKRDIRSYNARLLGLAMENKSEEMVSLFDKLKGNELKPDVFTFTAMIKGFVSEGKLDEAITWYKEIEKNGCRPLKFVFNSLLPAICKAGDLESAYELCKEIFAKRLLVDEAVLQEVVDALVKGSKQDEAEEIVELAKTNDYLQCKLRLFPKE
Protein: 6-phospho-alpha-glucosidase (EC 3.2.1.122) (Q9AGA6)
Organism: Klebsiella pneumoniae
Function: Is involved in the catabolism of alpha-glycosides accumulated via a phosphoenolpyruvate-dependent phosphotransferase system (PEP-PTS). Hydrolyzes a wide variety of 6-phospho-alpha-D-glucosides including maltose-6'-phosphate, isomaltose-6'-phosphate, maltitol-6-phosphate, trehalose-6-phosphate and the 6'-phosphorylated derivatives of the five linkage-isomeric alpha-D-glucosyl-D-fructoses: trehalulose-6'-phosphate, turanose-6'-phosphate, maltulose-6'-phosphate, leucrose-6'-phosphate, and palatinose-6'-phosphate. However, sucrose-6-phosphate is not a substrate for this enzyme.
Interaction partners:
Sequence:
MKKFSVVIAGGGSTFTPGIVLMLLANQDRFPLRSLKFYDNDGARQETIAEACKVILKEQAPEIEFSYTTDPQAAFTDVDFVMAHIRVGKYPMREQDEKIPLRHGVLGQETCGPGGIAYGMRSIGGVLELVDYMEKYSPNAWMLNYSNPAAIVAEATRRLRPNAKILNICDMPIGIEGRMAQIVGLKDRKQMRVRYYGLNHFGWWTSIEDLDGNDLMPKLREYVAKYGYVPPSNDPHTEASWNDTFAKAKDVQALDPQTMPNTYLKYYLFPDYVVAHSNPERTRANEVMDHREKNVFSACRAIIAAGKSTAGDLEIDEHASYIVDLATAIAFNTQERMLLIVPNNGAIHNFDADAMVEIPCLVGHNGPEPLTVGDIPHFQKGLMSQQVAVEKLVVDAWEQRSYHKLWQAITLSKTVPSASVAKAILDDLIAANKDYWPELH
Protein: ESF1 homolog (ESF1, nucleolar pre-rRNA-processing protein, homolog (S. cerevisiae)) (B8JKQ1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Interaction partners:
- Something about silencing protein 10
- ATP-dependent RNA helicase
- DEAD
- UTP6 small subunit processome component.
- UTP18 small subunit processome component.
- Nucleolar protein 6
- RNA cytidine acetyltransferase
- Activator of basal transcription 1
- Nucleolar protein 10
- Nucleolar MIF4G domain-containing protein 1
Sequence:
MTSKNTASGDDRFSKVKKDPRFWEMPNKERKIKIDKRFQSMFHDERFKLKYTVDKRGRPVKHTSTEDLKRFYKLSDSEQSDDDDDDEDEEKTEEEQKEKRGFEADKEAEVEEDDDDYEEEEGESDESEQEEEQKIQRNKEAKKTKKGVRVYEEDEDVESGVEEDDDDDDDDDEEESDSGPDLARGKGNIETSSDEDEEDEGDEVEDLLQREKEEIEHDWGEMWKDAPRSDDTSRRLAVCNMDWDRLKAKDLLALFNSFKPKGGVVLSVTVYPSEFGKERIHAEQTQGPLELSSLPENPDADTDEQRIYREKVRDYQFKRLRYYYAVVECDSAETASKIYEECDGIEYETSCSMIDLRFIPDDVTFDDEPKDRATDVDYGSYKPKLFTSTATTTSKVELTWDETDHDRVSALCRKFNKDELLDMDFKAYLASSSEEDEDEEEEQTKAVKPVESLPEEKKASKGKKGSGQIDKYRELLKSIQDKDKKKEDDDNNMNMEITWVPGLKESTENLVKKKMMGKDRLTPWEEFLEKKKEKKKEKRKGKKEVVEAELQISDDELPPDVDLSDPFFTEELVSTASLKNKESKKNRKKEEERTPEEQEEMERRKAEMELLMDDDEDDKHKHFNYDKIVEHQNLSKKKRKKLLKSNTPLEEGDDFKVDVQDPRFQAMFTSHLYNLDPSDPAYKKTKATQSILEEKQRRREEKHSQEETRRSKHTQEEDKTHTPSASSSTMDPSLSLLIKSVKNKTQQFQARKKQKTK
Protein: ER lumen protein-retaining receptor 2 (ERD2-like protein 1) (ELP-1) (KDEL endoplasmic reticulum protein retention receptor 2) (KDEL receptor 2) (P33947)
Organism: Homo sapiens (Human)
Function: Membrane receptor that binds the K-D-E-L sequence motif in the C-terminal part of endoplasmic reticulum resident proteins and maintains their localization in that compartment by participating to their vesicle-mediated recycling back from the Golgi. Binding is pH dependent, and is optimal at pH 5-5.4 (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:1325562, ECO:0000269|PubMed:18086916}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q5ZKX9}. Golgi apparatus membrane {ECO:0000269|PubMed:1325562, ECO:0000269|PubMed:18086916}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q5ZKX9}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000269|PubMed:18086916}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q5ZKX9}. Note=Localized in the Golgi in the absence of bound proteins with the sequence motif K-D-E-L. Trafficks back to the endoplasmic reticulum together with cargo proteins containing the sequence motif K-D-E-L. {ECO:0000269|PubMed:1325562, ECO:0000305|PubMed:18086916}.
Interaction partners:
- ER lumen protein-retaining receptor 3
- Coatomer subunit beta
- ER lumen protein-retaining receptor 1
- ADP-ribosylation factor 4
- Golgi phosphoprotein 3
- Leucine-rich repeats and immunoglobulin-like domains protein 3
- Coatomer subunit beta'
- Coatomer subunit delta
- Coatomer subunit zeta-1
- Transmembrane emp24 domain-containing protein 10
Sequence:
MNIFRLTGDLSHLAAIVILLLKIWKTRSCAGISGKSQLLFALVFTTRYLDLFTSFISLYNTSMKVIYLACSYATVYLIYLKFKATYDGNHDTFRVEFLVVPVGGLSFLVNHDFSPLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLVNWIWRFYFEGFFDLIAVVAGVVQTILYCDFFYLYITKVLKGKKLSLPA
Protein: DnaJ homolog 1, mitochondrial (P87239)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Iron-sulfur cluster biogenesis chaperone, mitochondrial
- Heat shock protein 78
- Endoplasmic reticulum chaperone BiP
- Heat shock protein 70 homolog C57A7.12
- J-type co-chaperone jac1, mitochondrial
- Mitochondrial import inner membrane translocase subunit tim14
- GrpE protein homolog
- Heat shock protein homolog pss1
- Probable heat shock protein ssa1
- Probable heat shock protein ssa2
Sequence:
MFSKYLQSRVCGLHSFTNSSAQQLFSKSIAHSSRRNFVISSSCTKFRNVAIQRNAKREFSRCAALKNFSYHARCFHATRAVWEMTDPYKTLGVSKSASASEIKSAYYKLAKQYHPDANPDKAAQDKFVEIKQAYEVLQDPKKKKAFDTYGAGAFKNGEFTGGDFEGFQNGFAGASSFSSGFPGFNFEDLFGFSSRGPQARRNTSFDVFVGEDIEASITIDFMEAVRGAKKDLSYSVSSTCSSCHGSGLQPGSHKSTCFACKGTGQRLHFIPPSFHMQTTCDSCGGTGTTIPPNSACRSCMGSGTVRERKTVSIDIPPGIDDNTVLRVMGAGNDASTAKGGPNAKSRPGDLFATIHVRKHPFFVREGTNVTYNAKIPMTTAALGGTLRVPTLTGNVDLRVSPGTSTGDRITMAGKGIRKVNTSRYGNFYVNFEVTIPKILSPHERSLLEQLADALNDSTARRTQSSPSGTNSSTSTSSTSSKHSTGISTEPTTGEENKQDGSVGGFFKRAFRRLHPDEDQNPKKDESSS
Protein: Histone H2B-alpha (H2B.1) (P04913)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular location: Nucleus {ECO:0000269|PubMed:16823372}. Chromosome {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Histone H2A-alpha
- Histone H4
- Histone H2A-beta
- Histone H3.1/H3.2
- Histone H2A.Z
- Histone H3.3
- Histone H3-like centromeric protein cnp1
- FACT complex subunit spt16
- Transcription elongation factor spt5
- RNA polymerase-associated protein C651.09c
Sequence:
MSAAEKKPASKAPAGKAPRDTMKSADKKRGKNRKETYSSYIYKVLKQVHPDTGISNQAMRILNSFVNDIFERIATEASKLAAYNKKSTISSREIQTAVRLILPGELAKHAVTEGTKSVTKYSSSAQ
Protein: Membrane associated ring-CH-type finger 1 (D6REN1)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000256|ARBA:ARBA00004439}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004439}. Early endosome membrane {ECO:0000256|ARBA:ARBA00004520}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004520}. Lysosome membrane {ECO:0000256|ARBA:ARBA00004155}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004155}.
Interaction partners:
Sequence:
MLGWCEAIARNPHRIPNNTRTPEISGDLADASQTSTLNEKSPGRSASRSSNISKASSPTTGTAPRSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFIMETKLKPLRK
Protein: Siderophore iron transporter ENB1 (Enterobactin permease) (Siderophore iron transporter ARN4) (Q08299)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in the transport of siderophore enterobactin and so has a role in iron homeostasis.
Subcellular location: Endosome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Iron transport multicopper oxidase FET3
- Facilitator of iron transport 2
- Facilitator of iron transport 3
- mRNA decay factor CTH2
- Plasma membrane iron permease
- Ferric reductase transmembrane component 5
- Facilitator of iron transport 1
- Iron-regulated transcriptional activator AFT1
Sequence:
MLETDHSRNDNLDDKSTVCYSEKTDSNVEKSTTSGLRRIDAVNKVLSDYSSFTAFGVTFSSLKTALLVALFLQGYCTGLGGQISQSIQTYAANSFGKHSQVGSINTVKSIVASVVAVPYARISDRFGRIECWIFALVLYTIGEIISAATPTFSGLFAGIVIQQFGYSGFRLLATALTGDLSGLRDRTFAMNIFLIPVIINTWVSGNIVSSVAGNVAPYKWRWGYGIFCIIVPISTLILVLPYVYAQYISWRSGKLPPLKLKEKGQTLRQTLWKFADDINLIGVILFTAFLVLVLLPLTIAGGATSKWREGHIIAMIVVGGCLGFIFLIWELKFAKNPFIPRVYLGDPTIYVALLMEFVWRLGLQIELEYLVTVLMVAFGESTLSAQRIAQLYNFLQSCTNIVVGIMLHFYPHPKVFVVAGSLLGVIGMGLLYKYRVVYDGISGLIGAEIVVGIAGGMIRFPMWTLVHASTTHNEMATVTGLLMSVYQIGDAVGASIAGAIWTQRLAKELIQRLGSSLGMAIYKSPLNYLKKYPIGSEVRVQMIESYSKIQRLLIIVSISFAAFNAVLCFFLRGFTVNKKQSLSAEEREKEKLKIKQQSWLRRVIGY
Protein: Rothein 3.2 (P86512)
Organism: Litoria rothii (Roth's tree frog) (Hyla rothii)
Function: Lacks antimicrobial activity. Does not inhibit the formation of NO by neuronal nitric oxide.
Subcellular location: Secreted {ECO:0000269|PubMed:16124032}.
Interaction partners:
Sequence:
DSAAGAVRAGDDETLLKPVLNSLDNLVSGL
Protein: Protein arginine N-methyltransferase 8-B (EC 2.1.1.319) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4) (zfL3) (Q5RGQ2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: S-adenosyl-L-methionine-dependent and membrane-associated arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q9NR22}; Lipid-anchor {ECO:0000250|UniProtKB:Q9NR22}; Cytoplasmic side {ECO:0000250|UniProtKB:Q9NR22}.
Interaction partners:
- Protein arginine N-methyltransferase 5
- Small ribosomal subunit protein uS5
- rRNA 2'-O-methyltransferase fibrillarin
Sequence:
MGLRHSSRCLLLRRKMAEAESTEQQQQKHKQPQHQQQQSISSIPSSQSLQPSPLPKPVTSVHHVPPHPPHTPHVSALSACPGRGKMAKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHIFKDKIVLDVGSGTGILSMFAAKAGAKHVYGIECSSISEYSEKIIKSNHLDSVITILKGKVEETELPVDQVDIIISEWMGYCLFYESMLNTVIYARDKWLKPGGFMFPDRATLYVVAIEDRQYKDFKIHWWENVYGFDMTCIRNVAMMEPLVDIVDPKQVVTNSCLVKEVDIYTVKTEDLSFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKTGFSTAPDAPSTHWKQTVFYLEDYLTVRRGEEILGSITVRPNENNERDLDFTFELDFKGQLCDAAISHDYKMR
Protein: Testis-expressed protein 12 (Q9BXU0)
Organism: Homo sapiens (Human)
Function: Component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase (By similarity). Requires SYCP1 in order to be incorporated into the central element (By similarity).
Subcellular location: Chromosome {ECO:0000250|UniProtKB:Q9CR81}. Note=In prophase I stage of meiosis, localizes in the transverse central elements of the central region between lateral elements of the synaptonemal complexes. Found only where the chromosome cores are synapsed. {ECO:0000250|UniProtKB:Q9CR81}.
Interaction partners:
- Synaptonemal complex central element protein 2
- Synaptonemal complex central element protein 1
- Synaptonemal complex central element protein 3
- Synaptonemal complex protein 1
- Synaptonemal complex protein 3
- Synaptonemal complex protein 2
- Protein SIX6OS1
- Structural maintenance of chromosomes protein 1B
- Meiotic recombination protein REC8 homolog
- Cohesin subunit SA-3
Sequence:
MMANHLVKPDNRNCKRPRELESPVPDSPQLSSLGKSDSSFSEISGLFYKDEALEKDLNDVSKEINLMLSTYAKLLSERAAVDASYIDEIDELFKEANAIENFLIQKREFLRQRFTVIANTLHR
Protein: Signal peptide peptidase-like 2A (SPP-like 2A) (SPPL2a) (EC 3.4.23.-) (Intramembrane protease 3) (IMP-3) (Presenilin-like protein 2) (Q8TCT8)
Organism: Homo sapiens (Human)
Function: Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in FASLG, ITM2B and TNF processing. Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF-alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus. Also responsible for the intramembrane cleavage of Fas antigen ligand FASLG, which promotes the release of the intracellular FasL domain (FasL ICD). Essential for degradation of the invariant chain CD74 that plays a central role in the function of antigen-presenting cells in the immune system (By similarity). Plays a role in the regulation of innate and adaptive immunity. Catalyzes the intramembrane cleavage of the simian foamy virus envelope glycoprotein gp130 independently of prior ectodomain shedding by furin or furin-like proprotein convertase (PC)-mediated cleavage proteolysis.
Subcellular location: Late endosome membrane {ECO:0000269|PubMed:16829952}; Multi-pass membrane protein {ECO:0000305}. Lysosome membrane {ECO:0000250|UniProtKB:Q9JJF9}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9JJF9}. Membrane {ECO:0000269|PubMed:15385547}; Multi-pass membrane protein {ECO:0000305}; Lumenal side {ECO:0000269|PubMed:15385547}. Note=Colocalizes with palmitoylated and myristoylated proteins at the plasma membrane.
Interaction partners:
- Tumor necrosis factor
Sequence:
MGPQRRLSPAGAALLWGFLLQLTAAQEAILHASGNGTTKDYCMLYNPYWTALPSTLENATSISLMNLTSTPLCNLSDIPPVGIKSKAVVVPWGSCHFLEKARIAQKGGAEAMLVVNNSVLFPPSGNRSEFPDVKILIAFISYKDFRDMNQTLGDNITVKMYSPSWPNFDYTMVVIFVIAVFTVALGGYWSGLVELENLKAVTTEDREMRKKKEEYLTFSPLTVVIFVVICCVMMVLLYFFYKWLVYVMIAIFCIASAMSLYNCLAALIHKIPYGQCTIACRGKNMEVRLIFLSGLCIAVAVVWAVFRNEDRWAWILQDILGIAFCLNLIKTLKLPNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGPFGNNEKLPVVIRVPKLIYFSVMSVCLMPVSILGFGDIIVPGLLIAYCRRFDVQTGSSYIYYVSSTVAYAIGMILTFVVLVLMKKGQPALLYLVPCTLITASVVAWRRKEMKKFWKGNSYQMMDHLDCATNEENPVISGEQIVQQ
Protein: Glycosyl hydrolase family 13 catalytic domain-containing protein (A0A1D8PP39)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Interaction partners:
- glucan 1,4-alpha-glucosidase
- Glucoamylase 1
- Glucoamylase 1
- Alpha-glucosidase
Sequence:
MTIEYTWWKDATIYQIWPASYKDSNGDGIGDIPGIISTLDYLKNLGIDIIWLSPMYKSPMEDMGYDISDYESINPDFGTMEDMQNLIDGCHERGMKIICDLVVNHTSSEHEWFKQSRSSKSNPKRDWYIWKPPRIDAKTGEKLPPNNWGSFFSGSAWEYDELTDEYYLRLFAKGQPDLNWENEECRQAIYNSAMKSWFDKGVDGFRIDVAGLYSKDQSFKDAPIVFPDQIYQPSGELISNGPRIHEFHQEMYRQVTSKYDVMTVGEIGHCDRNEALKYVSAQRKELNMMFLFDLVEVGSNNQDRFRYNGWNLIDFKKAIQNQSDFIKGTDAWSTVFIENHDQPRCISRFGNTKSLDLINKTGKLLAMLQASLTGTLFIYQGQEIGMTNLPRSWSIDEYKDINTINYYKDFKEKYGNEPDFKQREEKLLDVINLVARDHARSPVQWNDDDTESYGGFSTHKPWTRINDNYKQINVANELKDPNSILKFYQSVLKLRKEYKDLFIYGSFDILDFNNEKLFTYVKSHKEGNELPKAYVTLNFSNESIPFKPLIEGEFKLMTTNVQQSDYDESVLSPYEGRIYIVD
Protein: Anon1A3 (Q7KLU9)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
GVENLPSVAEAKQNHVDEVKPISEEPGNSSEEVPKAEEPLKSSGETSENGAATETAAAPKEPASVMDVDEDETLVENTPSANKEKALDDEKEPEQKSEEHAAAVLESKEQNEPAKEPTPEPMEVDGSSKGSSDTAQVDTPAIENVSAAPETEAAAKTTESSNDVVEVATEGKETVLEVPAAEPKEAESTVESAEELTETSTVVTEPKEAASSEEEPSKVVDSAEPKEAESNTDESATPVPIDVSTAPASNDVSKPLEIDTTLVKTADSPAKEPQEICEVKKAEINVNGEPKIVNSSAEVGENAAPKVCN
Protein: Probable ribosome biogenesis protein RLP24 (Ribosomal L24 domain-containing protein 1) (Ribosomal protein L24-like) (Q9UHA3)
Organism: Homo sapiens (Human)
Function: Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity).
Subcellular location: Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:35354024}.
Interaction partners:
- mRNA turnover protein 4 homolog
- Ribosome biogenesis protein NSA2 homolog
- Nucleolar GTP-binding protein 2
- Ribosome production factor 2 homolog
- GTP-binding protein 4
- Zinc finger protein 593
- 60S ribosomal export protein NMD3
- Ribosome biogenesis protein WDR12
- Large ribosomal subunit protein uL18
- Protein MAK16 homolog
Sequence:
MRIEKCYFCSGPIYPGHGMMFVRNDCKVFRFCKSKCHKNFKKKRNPRKVRWTKAFRKAAGKELTVDNSFEFEKRRNEPIKYQRELWNKTIDAMKRVEEIKQKRQAKFIMNRLKKNKELQKVQDIKEVKQNIHLIRAPLAGKGKQLEEKMVQQLQEDVDMEDAP
Protein: Hepatocyte nuclear factor 4-alpha (Q8AXB6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU004334}.
Interaction partners:
Sequence:
MEMADYSEALDPAYTTLEFENMQVLAMSTDSSPQESANMNAANHLGAGTLCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFNRQCIVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALIQADVLSRQISSPGPILNGDIRTKKVAAIMDVCESMKQQLLVLVEWAKYIPAFCDLPLDDQVALLRAHAGEHLLLGAAKRSMMYKDILLLGNDHIIPRNCPELEVSRVAVRILDELVLPFQDLQIDDNEYACLKAIVFFDPDAKGLSDPSKIKRMRYQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMAKIDNLLQEMLLGGSANEAPHAHHSLHPHLVQEHLSNNVIVTANMATPLHNGQMSTPETPIPSPPTASGSDHYKMASGVIATVPKQPSSIPQPTITKQEAI
Protein: Large ribosomal subunit protein uL6A (60S ribosomal protein L9-A) (L8) (RP24) (YL11) (P05738)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:22096102}.
Interaction partners:
- Small ribosomal subunit protein uS19
- Large ribosomal subunit protein eL6A
- Large ribosomal subunit protein eL30
- Large ribosomal subunit protein uL10
- Large ribosomal subunit protein eL20A
- Large ribosomal subunit protein uL3
- Large ribosomal subunit protein eL32
- Large ribosomal subunit protein uL23
- Small ribosomal subunit protein uS10
- Large ribosomal subunit protein eL6B
Sequence:
MKYIQTEQQIEVPEGVTVSIKSRIVKVVGPRGTLTKNLKHIDVTFTKVNNQLIKVAVHNGGRKHVAALRTVKSLVDNMITGVTKGYKYKMRYVYAHFPINVNIVEKDGAKFIEVRNFLGDKKIRNVPVRDGVTIEFSTNVKDEIVLSGNSVEDVSQNAADLQQICRVRNKDIRKFLDGIYVSHKGFITEDL
Protein: SET domain-containing protein 9 (EC 2.1.1.-) (Q8NE22)
Organism: Homo sapiens (Human)
Interaction partners:
- Cellular tumor antigen p53
Sequence:
MPGRLLRGLWQRWRRYKYRFVPWIALNLSHNPRTLRYVPEESKDKVISDEDVLGTLLKVFQALFLNDFNKQSEILSMLPESVKSKYQDLLAVEHQGVKLLENRHQQQSTFKPEEILYKTLGFSVAQATSSLISAGKGVFVTKGLVPKGAVVSMYPGTVYQKYEPIFFQSIGNPFIFRCLDGVLIDGNDKGISKVVYRSCNGRDRLGPLKMSDSTWLTSEIHNPLAVGQYVNNCSNDRAANVCYQEFDVPAVFPIELKQYLPNIAYSYDKQSPLRCVVLVALRDINQGEELFSNYYTIVS
Protein: Motility protein A (Chemotaxis protein MotA) (Q44456)
Organism: Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
Function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity).
Subcellular location: Cell inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Flagellar motor protein, PAL/OmpA family
- Flagellar motor switch protein FliG
- Flagellar hook-associated protein 1
- Flagellar L-ring protein
- Flagellar basal-body rod protein FlgC
- Flagellar M-ring protein
- Flagellar motor protein
- Flagellar biosynthetic protein FliP
- Flagellar basal body rod protein FlgB
- Flagellar motor switch protein FliM
Sequence:
MNIVIGLIITFGCIIGGYMAMGGHLNVLVQPFELMIIGGAGLGGFIMANPMKVVKDSGKALGEAFKHSVPKERNYLDVLGVLYSLMRDLRTKSRNEIEAHIDNPEESSIFQSAPSVLKNKELTSFICDYVRLIIIGNARSHEIEALMDEEIETILHDKLKPYHAITTMGDSFPAIGIVAAVLGVIKAMGKINESPEVLGGLIGAALVGTMLGIILSYSICNPLASQVKIVRTKQHRLYIIVKQTLIAYMNGSVPQVALEYGRKTISNYERPSIDAVEQEMMNPGGENKAA