wanglab/gogpt-training-data huggingface dataset:
Protein: Vascular endothelial growth factor A (VEGF-A) (Vascular permeability factor) (VPF) (P67964)
Organism: Gallus gallus (Chicken)
Function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity).
Interaction partners:
- Vascular endothelial growth factor receptor 1
- Vascular endothelial growth factor receptor 2
- Neuropilin-1
- Uncharacterized protein
- Fibroblast growth factor 2
- Placental growth factor
- Uncharacterized protein
- Hypoxia-inducible factor 1-alpha
- Fibronectin
- Collagen alpha-1
Sequence:
MNFLLTWIHWGLAALLYLQSAELSKAAPALGDGERKPNEVIKFLEVYERSFCRTIETLVDIFQEYPDEVEYIFRPSCVPLMRCAGCCGDEGLECVPVDVYNVTMEIARIKPHQSQHIAHMSFLQHSKCDCRPKKDVKNKQEKKSKRGKGKGQKRKRKKGRYKPPSFHCEPCSERRKHLFVQDPQTCKCSCKFTDSRCKSRQLELNERTCRCEKPRR
Protein: Nuclear receptor coactivator 1 (B5MCN7)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MNTSVYSILHVGDHAEFVKNLLPKSLVNGVPWPQEATRRNSHTFNCRMLIHPPDEPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQSCLICIARRLPRPPAITGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMGIHIIDREHSGLSPQDDTNSGMSIPRVNPSVNPSISPAHGVARSSTLPPSNSNMVSTRINRQQSSDLHSSSHSNSSNSQGSFGCSPGSQIVANVALNQGQASSQSSNPSLNLNNSPMEGTGISLAQFMSPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTSLQGMNEGPNNSVGFSASSPVLRQMSSQNSPSRLNIQPAKAESKDNKEIASILNEMIQSDNSSSDGKPLDSGLLHNNDRLSDGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSCTGTSNSASANSSGGSCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPDKKDSASTSVSVTGQVQGNSSIKLELDASKKKESKDHQLLRYLLDKDEKDLRSTPNLSLDDVKVKVEKKEQMDPCNTNPTPMTKPTPEEIKLEAQSQFTADLDQFDQLLPTLEKAAQLPGLCETDRMDGAVTSVTIKSEILPASLQSATARPTSRLNRLPELELEAIDNQFGQPGTGDQIPWTNNTVTAINQSKSEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKLVQGGGLDVLSERFPPQQATPPLIMEERPNLYSQPYSSPSPTANLPSPFQGMVRQKPSLGTMPVQVTPPRGAFSPGMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLIHQNRQAILNQFAATAPVGINMRSGMQQQITPQPPLNAQMLAQRQRELYSQQHRQRQLIQQQRAMLMRQQSFGNNLPPSSGLPVQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANPEASLANRNSMVSRGMTGNIGGQFGTGINPQMQQNVFQYPGAGMVPQGEANFAPSLSPGSSMVPMPIPPPQSSLLQQTPPASGYQSPDMKAWQQGAIGNNNVFSQAVQNQPTPAQPGVYNNMSITVSMAGGNTNVQNMNPMMAQMQMSSLQMPGMNTVCPEQINDPALRHTGLYCNQLSSTDLLKTEADGTQDKKTEEFFSVVTTD
Protein: Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (Never in mitosis A-related kinase 11) (NimA-related protein kinase 11) (Q8NG66)
Organism: Homo sapiens (Human)
Function: Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation.
Subcellular location: Nucleus {ECO:0000269|PubMed:12154088}. Nucleus, nucleolus {ECO:0000269|PubMed:15161910}. Note=Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase (PubMed:12154088). Accumulates in the nucleolus in G1/S-arrested cells (PubMed:15161910). {ECO:0000269|PubMed:12154088, ECO:0000269|PubMed:15161910}.
Interaction partners:
Sequence:
MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSEMTLEDKNLDCQKEAAHIINAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKLKKIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDEERWQGREEESDEPTLENLPESQPIPSMDLHELESIVEDATSDLGYHEIPEDPLVAEEYYADAFDSYCEESDEEEEEIALERPEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSLDTKTITTMAEDMSPGPPIFNSVMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNASEAEIRECLEKVVPQASDCFEVDQLLYFEEQLLITMGKEPTLQNHL
Protein: Cerebellin-3 (Q9JHG0)
Organism: Mus musculus (Mouse)
Function: May be involved in synaptic functions in the CNS.
Subcellular location: Endoplasmic reticulum. Golgi apparatus, cis-Golgi network. Secreted. Synapse. Note=In the absence of CBLN1, remains in the endoplasmic reticulum/cis-Golgi apparatus. Partial secretion depends on an association with CBLN1 and maybe CBLN4, but not on CBLN2.
Interaction partners:
- Gamma-aminobutyric acid receptor subunit alpha-6
- Glutamate receptor ionotropic, delta-2
- Protein NYNRIN
- Coiled-coil domain-containing protein 137
Sequence:
MGTEWHKPKLSLALVLLTLEAGWAQEGSEPVLLEGECLVVCEPGRPTAGGPGGAALGEAPPGRVAFAAVRSHHHEPAGETGNGTSGAIYFDQVLVNEGEGFDRTSGCFVAPVRGVYSFRFHVVKVYNRQTVQVSLMLNTWPVISAFANDPDVTREAATSSVLLPLDPGDRVSLRLRRGNLLGGWKYSSFSGFLIFPL
Protein: STarGazin (Mammalian calcium channel) homolog (TARP-like protein STG-2) (G5EBI8)
Organism: Caenorhabditis elegans
Interaction partners:
- STarGazin
- Suppressor of lurcher protein 1
- CUB domain-containing protein
- Glutamate receptor 2
- Protein cornichon homolog 1
- Glutamate receptor 1
Sequence:
MALGTIVEEHFHHPPLPTSPLSCKKTTHPEAPPVILLPQIGTNEMTLGERVSKFVIEARCTDNILFSGAMAVGACVLIMQSFPIFMNNWVFLTEPRGINKTNENGEQLESTFHYNTGYFQICRVHINNNSGIIYDEIEIPPSESEYKCYLNPLLSQVDLTDISLASLAVIIRLGLPALLHVSGALVCCFAFFLGVVGHIRSSFYTLFSSITYICGSIILCIAVLMVVCVVDDELAPRMKPNAAGEPSKFSYTYGPPFFSSALSFIPVQICACLHAFLYFRRYPSVVEKLQFVPGLEAKLRRAQLDKELGIPPLESFRRGSLASYLPIPSFSQGSRRNSRRSSQASFSNPSLLFMQDV
Protein: Sodium-dependent phosphate transport protein 2A (Sodium-phosphate transport protein 2A) (Na(+)-dependent phosphate cotransporter 2A) (NaPi-6) (Sodium/phosphate cotransporter 2A) (Na(+)/Pi cotransporter 2A) (NaPi-2a) (Solute carrier family 34 member 1) (Q28620)
Organism: Oryctolagus cuniculus (Rabbit)
Function: Involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. The cotransport has a Na(+):Pi stoichiometry of 3:1 and is electrogenic (By similarity).
Subcellular location: Apical cell membrane {ECO:0000250|UniProtKB:Q06495}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000250|UniProtKB:Q06496}; Multi-pass membrane protein {ECO:0000255}. Note=Localized at the brush border membranes of the proximal tubules. Internalized from the cell surface upon PTH stimulation. {ECO:0000250|UniProtKB:Q06496, ECO:0000250|UniProtKB:Q60825}.
Interaction partners:
- Sodium-dependent phosphate transport protein 2B
- Fibroblast growth factor 23
- Sodium/glucose cotransporter 2
- Klotho
- Sodium-dependent phosphate transport protein 1
- Parathyroid hormone
- Phosphate transporter
- Phosphate transporter
Sequence:
MISYGEQLSSPAVSPPLVRAGLRGPMMHGATFAYVPSPQALHRIPGTSAYAFPSLSPVALTEHGCPYGEARERHEPLPAKLALEEEQKPESGWAQELRRTAMTLLKLPLMVTFLYLFVCSLDVLSSAFQLAGGKVAGDIFKDNAILANPVAGLVVGILVTVLVQSSSTATSIIVSMVSSGLLEVSSAIPIIMGSNIGTSVTNTIVALMQAGDRTDFRRAFAGATVHDCFNWLSVLVLLPLEAATGYLHHVTGLVVASFNIRGGRDAPDLLKTITEPFTKLIIQLDRSVITSIATGDESLRNHSLIRIWCHRDPVEASTSMARAETNISRTHGNATMEKCNHIFVDTQLPDLAVGLILLAGSLVLLCTCLILLVKMLNSLLKGQVAKVIQKVINTDLPAPFTWVTGYFAMVVGAAMTFIVQSSSVFTSAITPLVGLGVISIERAYPLTLGSNIGTTTTAILAALASPREKLSSSFQIALCHFFFNISGILLWYPLPCTRLPIRMAKALGKRTAKYRWFAVLYLLVCFLLLPSLVFGISMAGWRAMVGVGAPFGALLAFVVLINVLQSRSPGRLPKWLQTWDFLPHWMHSLQPLDHLITHATLCCSRSEPRSPQLPARVFLEELPPATPSPRLALPAHHNATRL
Protein: 11-beta-hydroxysteroid dehydrogenase type 2 (11-DH2) (11-beta-HSD2) (EC 1.1.1.-) (Corticosteroid 11-beta-dehydrogenase isozyme 2) (NAD-dependent 11-beta-hydroxysteroid dehydrogenase) (P50233)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the conversion of biologically active 11beta-hydroxyglucocorticoids (11beta-hydroxysteroid) such as corticosterone, to inactive 11-ketoglucocorticoids (11-oxosteroid) such as 11-dehydrocorticosterone, in the presence of NAD(+). Functions as a dehydrogenase (oxidase), thereby decreasing the concentration of active glucocorticoids, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids. Plays an important role in maintaining glucocorticoids balance during preimplantation and protects the fetus from excessive maternal corticosterone exposure. Catalyzes the oxidation of 11beta-hydroxytestosterone (11beta,17beta-dihydroxyandrost-4-ene-3-one) to 11-ketotestosterone (17beta-hydroxyandrost-4-ene-3,11-dione), a major bioactive androgen (By similarity). Catalyzes the conversion of 11beta-hydroxyandrostenedione (11beta-hydroxyandrost-4-ene-3,17-dione) to 11-ketoandrostenedione (androst-4-ene-3,11,17-trione), which can be further metabolized to 11-ketotestosterone (By similarity). Converts 7-beta-25-dihydroxycholesterol to 7-oxo-25-hydroxycholesterol in vitro (By similarity). 7-beta-25-dihydroxycholesterol (not 7-oxo-25-hydroxycholesterol) acts as ligand for the G-protein-coupled receptor (GPCR) Epstein-Barr virus-induced gene 2 (EBI2) and may thereby regulate immune cell migration (By similarity).
Subcellular location: Microsome {ECO:0000250|UniProtKB:P80365}. Endoplasmic reticulum {ECO:0000250|UniProtKB:P80365}.
Interaction partners:
- Cytochrome P450 11B3, mitochondrial
- RNA-directed DNA polymerase
- Steroid 21-hydroxylase
- Aldo-keto reductase family 1 member D1
- 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 4
- NADPH-dependent 3-keto-steroid reductase Hsd3b5
- Mineralocorticoid receptor
- Glucocorticoid receptor
- Glucocorticoid receptor
- Epithelial sodium channel subunit gamma
Sequence:
MERWPWPSGGAWLLVAARALLQLLRSDLRLGRPLLAALALLAALDWLCQRLLPPPAALVVLAGAGWIALSRLARPPRLPVATRAVLITGCDTGFGKETAKKLDAMGFTVLATVLDLNGPGALELRARCSPRLKLLQMDLTKPEDISRVLEITKAHTASTGLWGLVNNAGLNMVVADVELSPVVTFRECMEVNFFGALELTKGLLPLLRHSRGRIVTVGSPAGDMPYPCLAAYGTSKAAIALLMDTFSCELLPWGIKVSIIQPGCFKTEAVTNVNLWEKRKQLLLANLPRELLQAYGEDYIEHLHGQFLNSLRMALPDLSPVVDAIIDALLAAQPRSRYYTGRGLGLMYFIHHYLPGGLRRRFLQNFFISHLLPRALRPGQPGPVHDTTQDPNPSPTVSAL
Protein: Homeobox protein SHOOT MERISTEMLESS (Q38874)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for shoot apical meristem (SAM) formation during embryogenesis. Negatively regulates ASYMMETRIC LEAVES1 (AS1) and ASYMMETRIC LEAVES2 (AS2 or LBD6). Probably binds to the DNA sequence 5'-TGAC-3'. Binds to RNA (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00559, ECO:0000269|PubMed:16513846, ECO:0000269|PubMed:29742441}. Cell junction, plasmodesma {ECO:0000269|PubMed:29742441}. Cytoplasm {ECO:0000269|PubMed:17965274}. Endosome {ECO:0000269|PubMed:29742441}. Cell membrane {ECO:0000269|PubMed:29742441}. Note=Association with TALE/BELL proteins is necessary for nuclear location (PubMed:16513846). Dynamic localization via a plasmodesmata-mediated cell-to-cell transport. This shuttle is repressed by MBP2C binding in cytosolic punctae, at microtubules (PubMed:17965274). Subcellular localization and trafficking is regulated by FTIP3 and FTIP4, which promote endosome localization (PubMed:29742441). {ECO:0000269|PubMed:16513846, ECO:0000269|PubMed:17965274, ECO:0000269|PubMed:29742441}.
Interaction partners:
- BEL1-like homeodomain protein 9
- Homeobox protein ATH1
- Homeobox-leucine zipper protein ATHB-23
- Homeobox protein BEL1 homolog
- AT-hook motif nuclear-localized protein 11
- Protein phosphatase 2C 32
- At3g13845
- AT1G25275 protein
- Transmembrane protein
- Secreted transmembrane peptide 5
Sequence:
MESGSNSTSCPMAFAGDNSDGPMCPMMMMMPPIMTSHQHHGHDHQHQQQEHDGYAYQSHHQQSSSLFLQSLAPPQGTKNKVASSSSPSSCAPAYSLMEIHHNEIVAGGINPCSSSSSSASVKAKIMAHPHYHRLLAAYVNCQKVGAPPEVVARLEEACSSAAAAAASMGPTGCLGEDPGLDQFMEAYCEMLVKYEQELSKPFKEAMVFLQRVECQFKSLSLSSPSSFSGYGETAIDRNNNGSSEEEVDMNNEFVDPQAEDRELKGQLLRKYSGYLGSLKQEFMKKRKKGKLPKEARQQLLDWWSRHYKWPYPSEQQKLALAESTGLDQKQINNWFINQRKRHWKPSEDMQFVVMDATHPHHYFMDNVLGNPFPMDHISSTML
Protein: PRA1 family protein (Q38A56)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MSASSDLDATSDEDENHFRRGNGSLVLQLSVLCDASFDQPQRPFGEFFCRPSMPTRETCTTTLLVNLLWFARNYYNLVLLASMGVILFAPPFALAVLSVSITYILRSRNGKSGAPCTSPQNDMLQKKKKGNHPTVMLFGLIRFLVFIGTCYVCGFLFITVCFVGVVALCLFHAMFTPYTDKAFELYSDVLCCRRLPLRLPCSPTRQFTCVDPSFDALSRQGSTVMSPRGGSCSKSSSPWMGTRTPEVLHHSFSSSSRPSQGEGIHNGWPLSESRRTVLSTQRGERLTGRRQSHLSEWGSRQQVRGRHRSPAALDVSDFQSDVEPHDSLVCAHAGTVRLTRVKESISISPMEQHLERNLSRMCSGFSGEAVTQGSVLDLCNDVCSALETAALEDEEGVFEQTTASQPIAPPTEAAPCLM
Protein: Small ribosomal subunit protein mS25 (28S ribosomal protein S25, mitochondrial) (MRP-S25) (S25mt) (P82663)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:25838379}.
Interaction partners:
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein uS12m
- Small ribosomal subunit protein uS11m
- Small ribosomal subunit protein uS14m
- Small ribosomal subunit protein uS15m
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein uS9m
- Small ribosomal subunit protein mS22
- Small ribosomal subunit protein uS7m
- Small ribosomal subunit protein uS10m
Sequence:
MPMKGRFPIRRTLQYLSQGNVVFKDSVKVMTVNYNTHGELGEGARKFVFFNIPQIQYKNPWVQIMMFKNMTPSPFLRFYLDSGEQVLVDVETKSNKEIMEHIRKILGKNEETLREEEEEKKQLSHPANFGPRKYCLRECICEVEGQVPCPSLVPLPKEMRGKYKAALKADAQD
Protein: IP13384p (Q8INZ6)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MFLLGICFICSLNPLVLNAFPVESQADSKDLSVLNAPLTDPADYPDLTNGLTDAEVQESLKDLTLDDLNSLNKLLDERLGRDEDVDSDASLTTHGRQAMANIRKQDFQSMEVGLDDNCRDEEDSDETKPNLCTKRPTCPTTKRCSRKSTCVPKTTRMCSTKSAYDSCKPKSGGFMDDDLISETTKSPKPKNKKCKKPKDDFECEADDFLCQASRRSRGKESRNTLLDEEYIPGRPLTGNAQLGDELTSALNDQGEPLNDAQMELSNSEFDNNLGLENPDSLEQGQPFDLGKDSKINTEQKHQTNLKNEYSRENLMQDYPKNLKHEPSGQLKEEDQANLDQNYNAKIDQEQSTGLELKSQSTLDQEDQFNLNKEYQPNLDFTNPVNFEQEHQSNFDSEYQNNFQKDHLTNWEKEHLANFDAGQSASLHQGEQQFNRNQKAPNVEGVDRSRQNEPIANEADPLDPNDRHQSSRTSLRKREQTEKQFEEHMPNEDDNKQASIKDELMPLNTDLPKQEHLFDSESFIANNARDPPRYLIQMQDDYIQSENDSGERRLLEDRRESEALNMDKLTEEEPRTMEEFHLDSEYRRKKRENKNTDDSPEKHI
Protein: Serine/threonine-protein kinase-like protein CCR2 (EC 2.7.11.1) (Protein CRINKLY 4 RELATED 2) (AtCRR2) (O80963)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Serine/threonine-protein kinase with low activity.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Interaction partners:
- ESCRT-related protein CHMP1A
Sequence:
MQPNSHIFVIITISSLIITVSAYGSTGTIAAAFGENGFFCAIDASGKQEVICWDRGNTNRSLNRPPGEISGYSPPMTSLSGGEGFLCAITSNTSRAFCWNLEDPSENLVPRAFQYNSYLQIASGNNHVCAISGLYYSGPDYGPVHCWEYSDNTNFTSGLLWNSSFHNPYIDSLMFRKIVSGDGFSCGVTKDGDLVCWGPKSNLLNFSNNEEFEVLASGRNSVCGVSKDSGQLHCFGDETEFGSLPNRPRFIALSAGANHYCGIREDDHGVECWGRNLNSSSSSSAPNTSGFVAISSSDSTTCGVRELDLVLDCWRVHDSSKADYSPPLELCSPGMCSPRGNCGDGWFAFNASILKESELTSLCSFHNLNICLRCGISCLEGYFPSSTCNPNADRVCTPCSLCQNSSCYGICKIRATKSKEHEQKEQREVRRLVIIIGCSVLGFLVMLIGLSFIPKMTKGSKRDDEERSKMTCCFCFDKNSVEADPDPVPHQSVLLPTAVSLGETKIFRLSELKDATHGFKEFNELGRGSFGFVYKAVLSDGIHVAVKRANAATIIHSNNRGFESELEILCKIRHNNIVNLLGYCSEMGERLLVYEYMPHGTLHDHLHGDLSQLDWSMRLKIMLQAARGLDYLHNEVDPPIIHRDVKTSNILLDGEMCARIADFGLVSSNERDSSNSDREGDVYDFGIVLLEILSGRKAIDRESDPAGIAEWAVPLIRKGKAAAIIDRNICLPRNVEPLLKLAELAELAVRENSNERPNIRNILCFLDLIVKSGLTF
Protein: Ubiquitin receptor RAD23d (AtRAD23d) (Putative DNA repair protein RAD23-4) (RAD23-like protein 4) (AtRAD23-4) (Q84L30)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in nucleotide excision repair (By similarity). Binds and presumably selects ubiquitin-conjugates for destruction. Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains. Acts as a ubiquitin receptor that associates with the 26S proteasomal docking subunit RPN10 for the indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP) (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:20086187}. Cytoplasm {ECO:0000269|PubMed:20086187}.
Interaction partners:
- 26S proteasome non-ATPase regulatory subunit 4 homolog
- DNA repair protein RAD4
- Peptide-N
- Probable ubiquitin conjugation factor E4
- Zinc finger A20 and AN1 domain-containing stress-associated protein 9
- 26S proteasome regulatory subunit RPN13
- Ubiquitin domain-containing protein DSK2b
- Protein DNA-DAMAGE INDUCIBLE 1
- Protein NBR1 homolog
- Calcium-binding protein CML19
Sequence:
MKIFVKTLSGSNFEIEVKPADKVSDVKTAIETVKGAEYPAAKQMLIHQGKVLKDETTLEENNVVENSFIVIMLSKTKASPSGASTASAPAPSATQPQTVATPQVSAPTASVPVPTSGTATAAAPATAASVQTDVYGQAASNLVAGTTLESTVQQILDMGGGSWDRDTVVRALRAAFNNPERAVEYLYSGIPAQAEIPPVAQAPATGEQAANPLAQPQQAAAPAAATGGPNANPLNLFPQGMPAADAGAGAGNLDFLRNSQQFQALRAMVQANPQILQPMLQELGKQNPQLVRLIQEHQADFLRLINEPVEGEENVMEQLEAAMPQAVTVTPEEREAIERLEGMGFDRAMVLEVFFACNKNEELAANYLLDHMHEFEDQ
Protein: 73 kDa paraflagellar rod protein (Q580L2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
Sequence:
MAAVDDATGLEAARKQKIHNLKLKTACLENEELVQELHVSDWSETQRQKLRGAHLKAEELVAAVDVGTKWNLTEVYDLAKLMRVCGLEMSQRELYRPEDKAQFMDIIAMKKVLQDLRQNRNKTRVVSFTQMIDNAIAKVEKVEEELRRSQLDATQLAQVPTQTLKQVEDIMNVTQIQNALASTDDQIKTQLAQLEKTNEIQNVAMHDGEMQVAEEQMWTKVQLQERLIDLIQDKFRLISKCEEENQAFSKIHEVQKQANQETSQMKDAKRRLKQRCETDLKHIHDAIQKADLEDAEATKRHAANKEKSDRYIRENEDRQEETWNKIQDLERQLQKLGTERFDEVKRRIEEIDREEKRRVEYSQFLEVASQHKKLLELTVYNCDLAIRCTGLVEELVSEGCAAVKARHDKTSQDLAALRLDVHKEHLEYFRMLYLTLGSLIYKKEKRMEEIDRNIRTTHIQLEFCVETFDPNAKKHADMKKELYRLRQGVEEELAMLKEKQAKALEEFKESEEALDAAGIEFNHPVDENNEEVLTRRSKMVEYRSHLTKQEEVKIAAEREEIKRARLLRSSGAGGEQVRIGNNTAPARLE
Protein: Ubiquitin-60S ribosomal protein L40 (Q8ID50)
Organism: Plasmodium falciparum (isolate 3D7)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
- 60S ribosomal protein L10, putative
- 40S ribosomal protein S19
- 40S ribosomal protein S19
- 40S ribosomal protein S4
- 60S ribosomal protein L13, putative
- 40S ribosomal protein S8
- 40S ribosomal protein S18, putative
- 40S ribosomal protein S7
- Ribosomal protein S27a, putative
- 60S ribosomal protein L32
Sequence:
MQIFVKTLTGKTITLDVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAIEPSLAQLAQKYNCQKLICRKCYARLHPRATNCRNKKCGRTNQLRPKKKLK
Protein: Acyl-acyl carrier protein thioesterase ATL4, chloroplastic (EC 3.1.2.-) (Acyl-ACP thioesterase ATL4) (Acyl-lipid thioesterase 4) (F4HX80)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acyl-ACP thioesterase involved in the production of fatty acids and beta-keto fatty acids. Can produce fatty acids of medium to long chain (6:0, 8:0, 10:0 and 16:1) and small amounts of medium to long chain beta-keto fatty acids (8:0, 14:0 and 16:1) when expressed in a heterologous organism (E.coli). Possesses thioesterase activity for lauroyl-ACP (12:0-ACP) in vitro. May play a role in the development of floral organs by generating short chain fatty acids.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:24214063}.
Interaction partners:
- Chaperone protein dnaJ 39
Sequence:
MIRVTGTAAPAMSVVFPTSWRQPVMLPLRSAKTFKPHTFLDLKGGKEMSEFHEVELKVRDYELDQFGVVNNAVYANYCQHGMHEFLESIGINCDEVARSGEALAISELTMNFLAPLRSGDKFVVKVNISRTSAARIYFDHSILKLPNQEVILEAKATVVWLDNKHRPVRIPSSIRSKFVHFLRQNDTV
Protein: Presequence translocated-associated motor subunit PAM17, mitochondrial (P36147)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to organize PAM16-PAM18 (TIM16-TIM14) heterodimer.
Subcellular location: Mitochondrion inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Interaction partners:
- Mitochondrial import inner membrane translocase subunit TIM17
- Mitochondrial import inner membrane translocase subunit TIM50
- Mitochondrial import inner membrane translocase subunit TIM14
- Mitochondrial import inner membrane translocase subunit TIM44
- Mitochondrial import inner membrane translocase subunit TIM16
- Import motor subunit, mitochondrial
- Mitochondrial import inner membrane translocase subunit TIM21
- GrpE protein homolog
- Mitochondrial import inner membrane translocase subunit TIM23
- Protein MGR2
Sequence:
MFTSAIRLSSQRLFASQPSVTAAALRSTATTLPLRSYSQPASLQDSSILTWSDFFKLRKQQRRINVGSSLFTALLGCNVSWAYLSTMEIDPTQMLFGFDPLTVISAGIIASGALGYLLGPIVGSQVFKLSHNQQLAQFNNKNKEFLKHIINNRVDASSQSFSNPVPDYYGEKIGSLKEYKQWLRDCHAYAKKAKEFL
Protein: Hemoglobin subunit alpha (Alpha-globin) (Hemoglobin alpha chain) [Cleaved into: Hemopressin] (P69905)
Organism: Homo sapiens (Human)
Function: Involved in oxygen transport from the lung to the various peripheral tissues.
Interaction partners:
- Hemoglobin subunit beta
- Haptoglobin
- Hemoglobin subunit delta
- Hemoglobin subunit epsilon
- Alpha-hemoglobin-stabilizing protein
- Hemoglobin subunit gamma-2
- Haptoglobin-related protein
- Small ribosomal subunit protein eS6
- NADH-cytochrome b5 reductase 3
- Small ribosomal subunit protein eS26
Sequence:
MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR
Protein: 1-aminocyclopropane-1-carboxylate synthase 5 (ACC synthase 5) (EC 4.4.1.14) (Ethylene-overproduction protein 2) (S-adenosyl-L-methionine methylthioadenosine-lyase 5) (Q37001)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: 1-aminocyclopropane-1-carboxylate synthase (ACS) enzymes catalyze the conversion of S-adenosyl-L-methionine (SAM) into 1-aminocyclopropane-1-carboxylate (ACC), a direct precursor of ethylene.
Interaction partners:
- Ethylene-overproduction protein 1
- 1-aminocyclopropane-1-carboxylate oxidase 4
- 5'-methylthioadenosine nucleosidase
- 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
- 1-aminocyclopropane-1-carboxylate oxidase 2
- 1-aminocyclopropane-1-carboxylate oxidase
- ETO1-like protein 2
- 1-aminocyclopropane-1-carboxylate oxidase 1
- S-adenosylmethionine synthase 1
- 1-aminocyclopropane-1-carboxylate oxidase 5
Sequence:
MKQLSTKVTSNGHGQDSSYFLGWEEYEKNPYDEIKNPNGMIQMGLAENQLCFDLIESWLTKNPDAASLKRNGQSIFRELALFQDYHGMPEFKKAMAEFMEEIRGNRVTFDPKKIVLAAGSTSANETLMFCLAEPGDAFLLPTPYYPGFDRDLKWRTGAEIVPIHCSSSNGFQITESALQQAYQQAQKLDLKVKGVLVTNPSNPLGTALTRRELNLLVDFITSKNIHLISDEIYSGTMFGFEQFISVMDVLKDKKLEDTEVSKRVHVVYSLSKDLGLPGFRVGAIYSNDEMIVSAATKMSSFGLVSSQTQYLLSALLSDKKFTSQYLEENQKRLKSRQRRLVSGLESAGITCLRSNAGLFCWVDMRHLLDTNTFEAELDLWKKIVYNVKLNISPGSSCHCTEPGWFRVCFANMSEDTLDLALKRLKTFVESTDCGRMISRSSHERLKSLRKKTVSNWVFRVSWTDRVPDER