wanglab/gogpt-training-data huggingface dataset:
Protein: Neutrophil cytosol factor 1 (NCF-1) (47 kDa neutrophil oxidase factor) (NCF-47K) (Neutrophil NADPH oxidase factor 1) (p47-phox) (Q09014)
Organism: Mus musculus (Mouse)
Function: NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:26021615}. Membrane {ECO:0000269|PubMed:26021615}; Peripheral membrane protein {ECO:0000250|UniProtKB:P14598}; Cytoplasmic side {ECO:0000250|UniProtKB:P14598}.
Interaction partners:
- NADPH oxidase 2
- Ras-related C3 botulinum toxin substrate 2
- NADPH oxidase activator 1
- Neutrophil cytosol factor 2
- NADPH oxidase 1
- Neutrophil cytosol factor 4
- NADPH oxidase 4
- Cytochrome b-245 light chain
- Ras-related C3 botulinum toxin substrate 1
- NADPH oxidase organizer 1
Sequence:
MGDTFIRHIALLGFEKRFIPSQHYVYMFLVKWQDLSEKVVYRKFTEIYEFHKMLKEMFPIEAGEIHTENRVIPHLPAPRWFDGQRAAESRQGTLTEYFNGLMGLPVKISRCPHLLDFFKVRPDDLKLPTDSQAKKPETYLVPKDGKNNVADITGPIILQTYRAIADYEKSSGTEMTVATGDVVDVVEKSESGWWFCQMKTKRGWVPASYLEPLDSPDEAEDPDPNYAGEPYVTIKAYAAVEEDEMSLSEGEAIEVIHKLLDGWWVVRKGDITGYFPSMYLQKAGEEITQAQRQIRGRGAPPRRSTIRNAQSIHQRSRKRLSQDTYRRNSVRFLQQRRRPGRPGPLSTDGTKDNPSTPRVKPQPAVPPRPSSDLILHRCTESTKRKLTSAV
Protein: At1g67862/At1g67862 (Q941E9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- At1g67860/T23K23_29
- Secreted transmembrane peptide 5
- Transmembrane protein
- AT4g05070 protein
- Transmembrane protein
- At4g19430
- DUF674 family protein
- AT1G25275 protein
- At3g13845
- Succinate dehydrogenase assembly factor 4
Sequence:
MLDKLIIGVAGGITGGILGTVDGFAKGVGIWPNNYQSTGRFENNNMTSPGNYGNGNGGAVKASENSGGRRQKDRE
Protein: Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (mACDP4) (Cyclin-M4) (Q69ZF7)
Organism: Mus musculus (Mouse)
Function: Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions (By similarity). May play a role in biomineralization and retinal function.
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- Solute carrier family 41 member 1
- Transient receptor potential cation channel subfamily M member 6
Sequence:
MAPGGGGGRRDGWPARGRLLLAALLLLWTRAASGQSSPQQSVILGMRLASCNKSCGMNPDGIIFVSEGSTVNLRLYGHSLGDISSNLISFTEVDDAEAVHNSTNCLELTKDLVVQRLVNVSRGNTSGMLVVITKFLRRSENMKLYALCTRPRADGPWTRWTDKDSLLFMVEEHGRFLPLWLHILLVMVLLVLSGIFSGLNLGLMALDPMELRIVQNCGTEKERKYARKIEPIRRKGNYLLCSLLLGNVLVNTSLTILLDNLIGSGIMAVASSTIGIVIFGEILPQALCSRHGLAVGANTIVLTKVFMLLTFPLSFPISKLLDFVLGQEIRTVYNREKLMEMLKVTEPYNDLVKEELNMIQGALELRTKTVEDIMTQLHDCFMIRSDAILDFNTMSEIMESGYTRIPVFEDEQSNIVDILYVKDLAFVDPDDCTPLKTITRFYNHPVHFVFHDTKLDAMLEEFKKGKSHLAIVQKVNNEGEGDPFYEVLGLVTLEDVIEEIIKSEILDESDMYTDNRTRKRVSVKNKRDFSAFKDTDNELKVKISPQLLLAAHRFLATEVPQFSPSLMSEKILLRLLKYPDVIQELRFNEHNRYCVRHYLYTRNKPADCFVLILQGKVEVEAGKENMKFETGAFSYYGTMALSVAPPDRSPALPTPLSRSASLSYPDRNTDLTSTSLAGSNQFGSCILGQYVSDFSVRALTDLQYIKITRQQYQNGLMASRMDNSPQPTFDGCATCSENFMERPELPPVDETTTLLNERNSLLHRASEEETI
Protein: Corticoliberin (Corticotropin-releasing factor) (Corticotropin-releasing hormone) (Q1HCN8)
Organism: Felis catus (Cat) (Felis silvestris catus)
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Interaction partners:
Sequence:
MRLPLLVSAGVLLVAFLPCPPCRALLSRGPIPRARQAPQQPQPLDFSQLPPQPQQPQQPQARPILLRMGEEYFLRLGNLNKSPAAPLLPASSPVSGGSGSHLSPDEAAANFFRALLQQLPLPRRPLPLDSPAGPAEHGAENALGSRQETLERQRRSEEPPISLDLTFHLLREVLEMARAEQLAQQAHSNRKLMEIIGK
Protein: Serine/threonine-protein kinase VRK3 (EC 2.7.11.22) (Vaccinia-related kinase 3) (Q8K3G5)
Organism: Mus musculus (Mouse)
Function: Inactive kinase that suppresses ERK activity by promoting phosphatase activity of DUSP3 which specifically dephosphorylates and inactivates ERK in the nucleus.
Subcellular location: Nucleus {ECO:0000269|PubMed:14645249}. Cytoplasm {ECO:0000250|UniProtKB:Q8IV63}. Note=Under oxidative stress, migrates from the nucleus to the cytoplasm. {ECO:0000250|UniProtKB:Q8IV63}.
Interaction partners:
- Dual specificity protein phosphatase 3
Sequence:
MISFCPVCGKSVKVSFKFCPYCGKALPVEEDGGTQSAVTPHVSSVPGSRRDLNSSFETSPKKVKCSHTVTSLPLSRHSDCDSSGSDNTLTSPDRATGTRSRPLTPKGSPLSNRQSPQTLKRTRVTTSLQALATGTELTDQNGKHWTLGALQIRDDQGILYEAEPTSAVPSESRTQKWRFSLKLDSKDGRLFNEQNFFQRVAKPLQVNKWKKQFLLPLLAIPTCIGFGIHQDKYRFLVFPSLGRSLQSALDDNPKHVVSERCVLQVACRLLDALEYLHENEYVHGNLTAENVFVNPEDLSQVTLVGYGFTYRYCPGGKHVAYKEGSRSPHDGDLEFISMDLHKGCGPSRRSDLQTLGYCMLKWLYGSLPWTNCLPNTEKITRQKQKYLDSPERLVGLCGRWNKASETLREYLKVVMALNYEEKPPYATLRNSLEALLQDMRVSPYDPLDLQMVP
Protein: bZIP transcription factor 17 (AtbZIP17) (O22208)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional activator involved in salt and osmotic stress responses. Functions as a stress sensor and transducer in a signaling pathway that resembles an ER stress response. Following salt stress, BZIP17 is cleaved by SBT6.1 (S1P) and S2P at the C-terminus and the N-terminal bZIP component is translocated to the nucleus, where it activates the expression of salt stress response genes. Functions as a stress sensor and transducer in ER stress signaling pathway. ER stress induces proteolysis of BZIP17 by SBT6.1 (S1P) and S2P, and the N-terminal bZIP component is translocated to the nucleus, where it activates the expression and production of ER chaperones, as well as protein involved in brassinosteroid (BR) signaling, which is required for stress acclimation and growth.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:20876872, ECO:0000305|PubMed:17662035}; Single-pass membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000305|PubMed:20876872}; Single-pass membrane protein {ECO:0000255}. Nucleus {ECO:0000269|PubMed:17662035, ECO:0000269|PubMed:20876872}. Note=Translocates to the nucleus following salt treatment, heat shock or tunicamycin treatment (ER stress) (PubMed:17662035, PubMed:20876872). Relocation of BZIP17 from ER to the nucleus occurs through the Golgi and is S2P-dependent (PubMed:20876872). {ECO:0000269|PubMed:17662035, ECO:0000269|PubMed:20876872}.
Interaction partners:
- Subtilisin-like protease SBT6.1
- Serine/threonine-protein kinase/endoribonuclease IRE1b
- Serine/threonine-protein kinase/endoribonuclease IRE1a
- Heat shock 70 kDa protein BIP3
- Basic leucine zipper 10
- Basic leucine zipper 9
- Membrane-bound transcription factor site-2 protease homolog
- Basic leucine zipper 8
- Kinetochore protein SPC25 homolog
- Kinetochore protein NUF2 homolog
Sequence:
MAEPITKEQPPPPAPDPNSTYPPPSDFDSISIPPLDDHFSDQTPIGELMSDLGFPDGEFELTFDGMDDLYFPAENESFLIPINTSNQEQFGDFTPESESSGISGDCIVPKDADKTITTSGCINRESPRDSDDRCSGADHNLDLPTPLSSQGSGNCGSDVSEATNESSPKSRNVAVDQKVKVEEAATTTTSITKRKKEIDEDLTDESRNSKYRRSGEDADASAVTGEEDEKKRARLMRNRESAQLSRQRKKHYVEELEEKVRNMHSTITDLNGKISYFMAENATLRQQLGGNGMCPPHLPPPPMGMYPPMAPMPYPWMPCPPYMVKQQGSQVPLIPIPRLKPQNTLGTSKAKKSESKKSEAKTKKVASISFLGLLFCLFLFGALAPIVNVNYGGISGAFYGNYRSNYITDQIYSQHRDRVLDTSRSGAGTGVSNSNGMHRGRDSDRGARKNISATESSVTPGNGSEPLVASLFVPRNDKLVKIDGNLIINSILASEKAVASRKASESKERKADLMISKDYTPALPLPDVGRTEELAKHLYRSKAEKQKALSSGSADTLKDQVKTKAANGEMQQWFREGVAGPMFSSGMCTEVFQFDVSSTSGAIIPAATNVSAEHGKNTTDTHKQQNRRILRGLPIPLPGSDFNLTKEHQRNSSSKEIKPASSMVVSVLVDPREGGDGDIDGMIGGPKSLSRVFVVVLLDSAKYVTYSCVLPRSGAPHLVTT
Protein: Insulin receptor substrate 2-A (IRS-2-A) (Insulin receptor substrate-undetermined designation) (Insulin receptor substrate-unique) (xIRS-u) (Q9DF49)
Organism: Xenopus laevis (African clawed frog)
Function: Potentiates insulin signaling.
Interaction partners:
Sequence:
MAGVLCPTEEDRSSRAALRMLPPQPCPDESGAYRRMSGPTLSQVQEEPAAEPPQPPASAAEDDVRKRGYLRKQKHGHKRYFVLRSQSHLGPARLEYYDNEKKFRSGQRSGCHPKRVIPLYLCFTVSRRADAKNKHLVALYTKDEYFAMAAENEQEQDGWYQALSELINESKGACLDTEELEENYGTLRPGTVFKEVWQVNVKPRGLGQAKNLSGVYRLCLSSKAVHLVKLNSDVACVHLLLMNIRRCGHSENYFFIEVGRSSSTGAGELWMQVDDCVVAQHMHETFLDTMKALKAYSEFRPRSKSQSSCTNPISFITTRRYLGNLPPSQTGLQRRARTESMVGTPPSAKNNSFRFRTSSEGEGTMTRPFRSVTGSLSHLNTARINLGKQEGAGRYVRAPFNSGYQSRSASLPVSHFPSATSPISVCSSSGHGSASETLTRPSSSSVCGSPSDGGFISSDEYGSSPGDLRYFRVRSNTPDSLGNTPPIQEENTLSDYMSMSTHSQPDSRDDYMEADKCFRKRTYSLTKHTNSASKQKSQTAISLGEDSEEINKQFAFAESPKLKDSSLVDDYSNGVIDSVCNQSRSKASDDGYMPMMPSNLYDSDYLPMAPKTVSAPKQINRCPSQADSKGYMMMFPINSSPVKNVFGGAATKSNLEKLSNGGYMDMSYGNSTKQIHDSNLNNNSRGLSSYFSLPRSFKSLTKQTTDQNEYVPMSSPGKLLHLGAENGVDVCKDGAVHDIAKIELKSSSSILDQQVKRPNKLTLGIRGSNTIPRMFDHSAPAEPTSPGEYINIDFSDKASSTPYSLSADGSPSSLGSSCDHRQSPLSDYMSVDIDVQSPKATAEQSNSLTDISLYACTVVSRMQPNAEYAKLPCGTACVSKTDNIMDDYTTMTFNMAMTPPRSFASETENGTKVDSPSSIVNRLCIGELTSLNSGFSLPNPLPEPIAGPKVIRADSQGRRRHSSETFASSSTVTTSSSCFTESGKRHSSASFDNVWLKPDENSCEQENKMSRHCSTGFQNGLNYISLSMHNGVCEPTSPDCHQHQNGSRNLESGGYVSIDFTRCDCLKCPTSRKD
Protein: Protein mago nashi homolog (O43037)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Uncharacterized RNA-binding protein C23A1.09
- Uncharacterized protein C19C7.01
- ATP-dependent RNA helicase fal1
- Nonsense-mediated mRNA decay protein 3
- Uncharacterized RNA-binding protein C106.12c
- RNA-binding protein with serine-rich domain 1 homolog
- ATP-dependent RNA helicase eIF4A
- Importin beta-like protein kap111
- mRNA export protein mlo3
- Pre-mRNA-splicing factor cwf22
Sequence:
MSDFYVRYYSGHHGRFGHEFLEFDYHSDGLARYANNSNYRNDSLIRKEMFVSELVLKEVQRIVDDSEIIKESDESWPPENKDGKQELEIRMNGKHIMFETCKLGSLADVQNSDDPEGLKVFYYLIQDLKALCFSLISLNFKLRPVKN
Protein: Rifin (Q8I2E6)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MKLNYTKILLFFFPLNILLTSPSNSHNNNNEPQTTPHHTQTNRSLYESDTESSIYDKDEDMESVKENFERQTSQRFEEYQERMKEKQQKRKEQRDKNIQKIIHKDKMEKNLAEKIEKGCLMCGCGLGSVAGSVGLFGGIAINIWKPTALDAAIEAAIAKSAAKITAVAEAARILAGKEAVIAGLEKLGVSILDNQLLVSYFTTTPYNTASVITTALYKQHYKICVYDPSRNLLSSFGDVNRHIGICNSVWKQISVVSQRGQYISHEEVIKRTVETMVSYAEVSAKAAAKTAEVAEKATIKVAQEKVMEATIYNWYTTIGYTILAILIIVLIMIIIYLILRYRRKKKMKKKAQYTKLLNE
Protein: Polynucleotide kinase 3'-phosphatase, putative (Q585Q2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- DNA repair protein, putative
- Protein artemis
- Enkurin domain-containing protein
- DNA polymerase
- Mitochondrial DNA polymerase beta-PAK
Sequence:
MKRARSPSPKGLSLATIADWKLLHNSVLALLPSAEQLKRSITSLPGENLCLKVAAFDLDDTLIMPKTGAVFPRDDPTDWKWLTPLVPTHLRVLHDGGFMVVIFSNQAGIGGKQWNEKKADVVKQKVVRLSKGLNIPLTAFLSTKDDIWRKPNVGMWTMLQEHASDILKEKVVIGSDTCGYAFYVGDAAGRKITTLAGRKKDFSCSDRKFAYNIGIPFFTPEEFYSCPEDKLLEERKKGSDDTPSVDGKVVSHRLLNVAQASCTVDWGGVGPTELSKLPKSYSGLTIHRILANGTKDIIEVSSPAAFHRASQEMIVFVGYPGCGKTTFFERFFEPHGYAHVNRDKLQTREKCLAEARRWWKAGKSVVIDNTNPSHEDCRVFVEVVKQDGSGRSPLPVRLFLFRISKEMSMHMSNVRARLGVAPKISRVAYNVYQSKFDSWTADSVRSMGIEELVEIPPVASFDGLPKDSKREFFLLS
Protein: Peptidase S1 domain-containing protein (Q9D960)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MLLLSLTLSLVLLGSSWGCGVPAITPALSYNQRIVNGENAVPGSWPWQVSLQDNTGFHFCGGSLISPNWVVTAAHCQVTPGRHFVVLGEYDRSSNAEPVQVLSIARAITHPNWNANTMNNDLTLLKLASPARYTAQVSLVCLASTNEALPSGLTCVTTGWGRISGVGNVTPARLQQVVLPLVTVNQCRQYWGARITDAMICAGGSGASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKNCNIQAPAMYTRVSKFSTWINQVMAYN
Protein: Mitotic spindle assembly checkpoint protein MAD2A (Mitotic arrest deficient 2-like protein 1) (MAD2-like protein 1) (Q556Y9)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex until all chromosomes are aligned at the metaphase plate (By similarity).
Subcellular location: Nucleus {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000250}. Cytoplasm {ECO:0000250}.
Interaction partners:
- Probable inactive serine/threonine-protein kinase bub1
- Anaphase-promoting complex subunit 4
- Anaphase-promoting complex subunit cdc20
- Mitotic checkpoint protein bub3
- Probable serine/threonine-protein kinase mps1
- Anaphase-promoting complex subunit 6
- Anaphase-promoting complex subunit 1
- Anaphase-promoting complex subunit 8
- Anaphase-promoting complex subunit cdh1
- Anaphase-promoting complex subunit 10
Sequence:
MQAAVASKTNISLKGSTEIVTEFFSYSINTILFQRGLYPPESFTRVAKYGLPILVTNDQSLKDYLDNVLKQLSEWLLSGDVQKLVLVITDIVTKEVLERWVFDVTTDIPKEGEAPRQKPEKEIMNEIQAIIRQITASVTFLPLLPNACTFDLLVYTSKDLAVPQKWEESDPKFITNSQQVKLRSFTTTIHKVESMVAYKISND
Protein: Pregnancy-specific glycoprotein 23 (Q9R1F9)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MGVTSELFTNVLIPWQRVLFTASLLTCWLLSTTASVTIQSPQHVVEGENILLQVDNLPENLLAFAWYRGLTNWRLTIAVYLLDYSTSMTGPEHSDREILYSNGSLWIQNVTQEDTGYYTLQTISNHGELESNTSTFLQVYSSHFTCGRPSFPAKLTIESVPPRVAEGGSVLLHVHNLPEYLQLFFWYKGVIMIHKVEIVRHRTLKNLSDPGPAHSGREIVYSNGSLLLQNVTWKDTGFYTLQTVNRYWKMELAHIYLQVDTPCCDPLDSAQLRIDPVTPHAAEGESVLLQVHNMPEDLQTFSWYKGVDSTPSFRIVEYSKAMMSIISGSANSRREIGYTNGSLLLQDVTEKDSGLYTLVTIDSNMRVETVHVQVNIYKLVTQPVMRVSDTIVRVQSSVVFTCFSDNTGVDIRWLFNKQSLQLTERMSLSPSKCQLRIHTVRKEDGGEYQCEAFNPANSKTSLPVSLAVMNE
Protein: Peptidase, putative (EC 3.4.24.-) (Q57YQ9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Interaction partners:
- CAAX prenyl protease
- Cytosolic leucyl aminopeptidase, putative
- Peroxin-13
- Peroxisome targeting signal 1 receptor
- Polyubiquitin, putative
- Proteasome 26S non-ATPase subunit 9, putative
- Nonspecific lipid-transfer protein, putative
- propanoyl-CoA C-acyltransferase
Sequence:
MTREEVRIVTPSVLRVQHFGYIFKNGVKCIVVQDPNARVPAAAMNIRAGQLNDPEVLPGLAHFCEHMLFMGTEKYPSEGEYSDYITKNGGYCNAWTADRGTTYYFTVAQDALQGALERFVEFFIAPSFDASSISREVKAVHSEDEKNHSVDFWRQDELLRSLCDPRHPRSRYGNGNMTTLWDEPLQKQVDIREQLLKFFEAHYVSGAACIAVYSAFPPEWVLSIIEEPLSKMRVGEPSPFRFMQPSDPLLRSTASGGLWLNVRTVRKTRSIAMIWPVKSHSSLWRSSPSGYVSYILGHECDSSVFGILRQQGLAVAMSVGPRRIDDDNELFCVDISLTLDGVRCIPDVIDMVYQGIGQTAHVDTSVYEHMKSEELLSFESCDISGYADHCVELAYSANETDLPNCWVSGNRVLEDDIHATEEYVAQLTPEKCVITFMWGDMPCSTDDDTPREEGPESAIEEEEEDAEESEEEQCASSVFHTLPNFAQIPCNCATRFHKTKFSLCRVPDDLLRRWAASLHKPTQAGLSLPPPNPFLATDFTLYNEGSSDGHCEPAVETFNTMYGVTLMRKNVWHYQTFKSSIHWCALSPCVYATPKNRFYARVMRSILKDALAEVSYFGVLASLENSVELSTGGISLSVTGPQQRIVDFFFSLFEKFFSPNVLRGTAEKYNTYSEVALRHLVGSAAKQPYELVNDAFVKVGKVVMYTFDEILNAASSISYKEYLSFVDEYLRSGIYFECFIAGNIPSASYMRECLLDTMEKKLSCMNVPPAPKESIPRFRDAYAFSRDSSKLGTPVVSVMSYPPFNPENPNVAVLLDIYVGEETAMVRALCDCMNKLLSSSFFNELRTKEALGYIVFSRSLRLQGTAHLQFGVQSAVEGVDGLYLFSRIIAFLAAVEEKLVAVCSETDVQTVVSGLIEARKKLPDSADHDCDDLSGRYLNPLGIQGKEAVVAALEQVSPQMVREFFQTYVANSNPHRKAVLTIVNSSASAATDAFNTDQEEVALPSRRPCEGAQPIDGDDVAAANRGCVLNLPDFTAVPMRIAIKRYGSPQEFQANLPVIRCRTF
Protein: Probable metabolite transport protein YFL040W (P43562)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Membrane; Multi-pass membrane protein.
Interaction partners:
Sequence:
MTAMKAIVWRLPKMPKIKITKTYEVTKITAILTLVGFIMGLEVPSLATFLTNKTFNEYFKYPTPLQQGLLMGSTPLGGIMGCFICCIMNDRFSRIYQFQSGIIIWNIVTLLNFCIWDILGLLICRMIKGMILGNFSILVASYANEVIPRGKRGSTMSYIQLCLTIGILVMHYLCIALSLWDSHFAFRIAWCIGIIPGLLFWMASYALPESYHWLVLHGKMSEAQEIQHNLAKKFNESQPRDAVPEMSKIELAGDFWIGVNDLDFSKKLPRGSFKPLILGMTLQLLVQFSGINIILGYITYICEIVGLEGNVKLFTSSIPYFINMVLSLLPITFIDYTSRKLITLLGGFPISGLLITIGALFVKYGQDTKPIDGNRSLVWSIGENPFVGGWILTLCFLIVGIFAMSLSSIPWVYTNEMLPSRVKVKGFAICVTFGWLGNFILTFLCPVMIERLKGTTFIIFGSLTFLISLSVLIWFPETKGMSIEDIDKFFEFESKEGTNLHGEKGIKTPDSNSNGGSTRSSQEGQLHKPIKLKSDEEMII
Protein: MICOS complex subunit Mic10 (Mitochondrial inner membrane organizing system protein 1) (Q7TNS2)
Organism: Mus musculus (Mouse)
Function: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Subcellular location: Mitochondrion inner membrane {ECO:0000250|UniProtKB:Q5TGZ0}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q5TGZ0}. Note=The C-terminus is located in the intermembrane space, while the location of the N-terminus has not been determined yet. As some programs predict the presence of 2 closely apposed membrane domains, it has been proposed that the protein may cross the membrane twice and that both termini may face the intermembrane space. {ECO:0000250|UniProtKB:Q5TGZ0}.
Interaction partners:
- MICOS complex subunit Mic60
- MICOS complex subunit Mic25
- MICOS complex subunit Mic19
- MICOS complex subunit Mic27
- MICOS complex subunit MIC13
- MICOS complex subunit Mic26
- DnaJ homolog subfamily C member 11
- Sorting and assembly machinery component 50 homolog
- Coiled-coil-helix-coiled-coil-helix domain containing 10
- Metaxin-2
Sequence:
MSESELGRKWDRCMADTVVKLGTGFGLGIVFSLTFFKRRMWPLAFGSGVGLGMAYSNCQHDFQAPYLLHGKYVKEQ
Protein: LD33016p (Q95SZ8)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MKSRRSCSRLSKLYEDCSCVVNDPAPKSAAQRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTRRSTSDSVIRPGICTKNCNWSFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLALMMISLLALIPGPIIFGRLIDSTCLVWTKTCNGNGNCQLYDQTRFRYSLNFLSCLLTFMGLLFDYLVWYYGRNLDIYGDKEAKEEERANRKDQPITPLLAKKSEQE
Protein: Membrane-associated sulfotransferase kil1 (EC 2.8.2.-) (Q55GK8)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Sulfotransferase involved in intracellular killing of bacteria.
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Interaction partners:
- Intermembrane lipid transfer protein vps13F
- Putative phagocytic receptor 1a
- Integrin beta-like protein A
- Glycosyltransferase
- Large ribosomal subunit protein eL15
- Putative lysozyme-like protein
- Lysozyme A
- Putative phagocytic receptor 1b
Sequence:
MSTTSMILTKKNIIILSIIIITIIAYQFYITSPQSFPSSNTITNTINTSGKGLDYTELLNLQKDLKAQQTEIRKQLEQLKYSINDINQNQNENQNQINNEYNNNKLNDEQENNNNNNYNNNNNNNNNELINYKERIKKKSKEQPNTCIPVEGKLLCLPNFIVIGTMKSGTTFLDYYLQKHPQIAHHSKKEIWYFNSYYANGIEWYAKHFEQYTSLENQKLIGEATPFYINNPNTAPRLFTTLKNAKLILLLRDPVERSLSQYHFSIQWLKRNKSPPLEYSFEHLIHEEADVIETCIRGHERYKEAFKQRKEIEKNGGGGLLNDNTSGEEFNLVDPFYTLHSEKNWTFYKDCIRCDKCFQIGSILHTSGHPTFGMLAKSLYFEQLDYWLNFFPLEQIHIIRYEDISSQPESVLSELEDFLDINHIDYGEFKPRNVVQHDPMNQEIKSYLINYFKQSNEKLYNLLNRDFKWQN
Protein: Pleckstrin homology (PH) domain-containing protein (F4JPD9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
Sequence:
MDDGTPKKLNILPDHFSAPSPTAESSQHDTPSSSQPKDDSSLRPYSQSRTRRNLKRAATMLNLFTLRRLPWVSDGQEKVELSAAELESLRSELSDMEEREAYLKAQLEHVDEVLRSARLSGYLFIRSRWAALPGEPPPIDDTEVDDWLPRFVVLQGPCLFFYLLSTDLSPQDSTLLADIVEIGSVPSYTREFDETHYCFYILTRQGLRFECSSTSKTQVDSWLSVLRLDCKSEPEERLSNGSVEAPE
Protein: GPI mannosyltransferase 3 (EC 2.4.1.-) (GPI mannosyltransferase III) (GPI-MT-III) (Glycosylphosphatidylinositol-anchor biosynthesis protein 10) (Q9USN0)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Interaction partners:
- GPI ethanolamine phosphate transferase 3
- GPI transamidase component gaa1
- GPI mannosyltransferase 2
- GPI mannosyltransferase 1
- GPI ethanolamine phosphate transferase 1
- GPI-anchor transamidase
- Dolichol-phosphate mannosyltransferase
- Probable Dol-P-Man:Man
- Dolichol phosphate-mannose biosynthesis regulatory protein
- Dol-P-Man:Man
Sequence:
MRIWFWLAILVFRWWNALWVKTFFQPDEFYQSLEVAHHFIFRYGFLTWEWTSAIRSALHPLIFAALYRVLQVLKLDSSYFVFTNAPKLLQGTFAAILDYGTYKFALVRYGSKTANWTLACSLVSIMNAYVGVRTFSNSLETTLTSIGFYYFSYYLKYENSSPEQRKKAYSSLLGFISVAAFACFIRPTNILVWIFPLLFWNKNPQTPIKDLLSFSNVFNRFRFLYALGYGRLFGIFVLCVSLFLVNIIADRILYGRFVFPIISFFQFNVTSGLSSLYGLNAWHYYLSQALPLICGGFLPFVLLTMDLQTAGTILCVFFPYSLIGHKELRFVYPISPILLTLAGKFFSSFSSWKRAARFFFLIGLGHALVITFLCRFHQFGVMEVMPLIHSLAEKNQTGLILAPCHTTPWQSHIHSPFAENGWKFLTCEPFEKPFDETDRFYENMPTFLDKIKEWPDYLIFFEERFYSLYSYLDSRGLKYEEVQRYYNSLIPESRERAGALLVYKKL
Protein: Jabba, isoform I (A0A0B4KG78)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MAQETKTVATAKDQNQRDHIDEEEVIELHESRSFYDRVREQAERFASTRVGQFVIERADKALAMIEDTAKWSLPQDKSSAPLERPLPWAPFLMLIVLLRLTRIWLSVGALMIGNGPISPTDMVYFIQTRRRKLRAIRVHGLKVMRRRQQEVSYGSGKGMTQKLNQWFSRAMCRPGVQQDSSSRRVFVRHSEQGLSNFVVKRPREEDCNADADLTIDQMLAKYANENSEDDSDFVPNEEEEEEESSSSSGESESESGSSEGISSGEVDEVVSQPKQKSAGAVVENGVHKAEEKENDKGKLNITTTSNGNNDKEQADVGSPTCFNTSLGTQALLKRASIQSVLAHSTPTTEMRDQPIEEANNSVPQTPETEKTQPQTPKEVHNQNQQQNQQQRQRNHPHQRYRGRNRR
Protein: Zinc finger protein 318 (Testicular zinc finger protein) (Q99PP2)
Organism: Mus musculus (Mouse)
Function: Acts as a transcriptional corepressor for AR-mediated transactivation function. May act as a transcriptional regulator during spermatogenesis and in particular, during meiotic division.
Subcellular location: [Isoform 1]: Nucleus {ECO:0000269|PubMed:12589823, ECO:0000269|PubMed:16446156}.; SUBCELLULAR LOCATION: [Isoform 2]: Nucleus {ECO:0000269|PubMed:12589823, ECO:0000269|PubMed:16446156}.
Interaction partners:
Sequence:
MYRSGSRSSVSSHRSKDGSASGPPPGRPVGASSGPTRRPSSPPPPSCSSLRLPARRHRSPSGHRGRWASPSPPRGRRGSPSPPRGRRASPSPTRGRRASPSPPRGRRGSPSPPRARRGSPSPPRSRRHYPPGLGGFRGSIRGESRADFARDGRGDHPGGGGGSRRRSPGLCSDSSLEESLRITVGNDHFCVSTPERRRLSDRLGSPVDGLQDMDRDDLTDDSVFTRSSQCSRGLERYISREEGPLSPFLGQLDEDYRTRETFLHRPEFSPQSSCHDELLRGTERNRDKLKSSSYSIRSEERSREAKRPRYDDTEKVHSSGGDHSSFTSGTRNYRQRRSSPSPRFLDPEFRELDLARRKREEEEEQSRSLSQELVGVGDDQIGCSIPGLAGVLTTSEPGYSLQRPEEVPMMPKKSILKKRIEADMKPSLQLESFSSGASSGEDHPLYSEHSPLPLSGAIAAFTSEIENKGTTVEADLKEPQSNLYQWGPLREIPKDNSEKFDSFLGFKEKLDLKAEGLEQQTDFLLPHERASQDGSGFSRILSMLADPTITQEKRRRSFPDIEDEEKFLYGDEEEDIKSESPLKSLEDPESAGTRQKANSLPSTPAVKLESLEESNPEYAKIHNLLKTIGLDIGVAEIGKLAARTQERLHGKKPSSRPSADRRLSADRHLSGDRHFSADRCSSVEHSFTADWRSSDPHRPESRETHHSNTQSPEVSHPHPASPVDPYLRTKNSPPFLKSDHPVCHVSGPEVVGSGFQSSVAVRCMLPSAPSTPIRLPHSAALSQFHIPGASQFAAARIPPNYQGSVIPSASFDAYRHYMAYAASRWPMYPASQPPSHPLSDPHRLLPVTKQAARSRPNLRVIPTVTPAKPKQEIPVLGSISVKRIPVRVSIPSLIKYNPKKISDEKNRASQKQKVIEEREKLKTEQEARQKKMFYLTTELERLHKQQGEMLRKKRREKDGHKDPLLMEVSRLQDSIMKDIAELHKETEEAEKKQSELDKVAQILGIDIFDKSLKSSNDSKESTEKPEKEKSKSPEKELSPSNSSSSNKESKMNEKSCIKSPSSTESLQPTVKQSDQPVAAYEYYDAGSHWCKDCNTTCGTMFDFFTHMHNKKHTQTLDPYNRPWASKTQSEAKQDTVKRTDKITVPAKGSEFLIPVTGFYCQLCEEFLGDPISGEQHVKGHQHNENYKKYVEENPLYEERRNLDRQAGLAVVLETERRRQNELKRKLNEKPKEEKIEKKARIVREVKEDDKAPGELEEQLSEDGSAPEKGEVKGNASLRPQVKEEVKKEPSVASIAASFGKFSWKKPEKEEEKGSVVTPGAPKEDTVETSKDRDDGKAEVGKAKPIKIKLSGKTVIAHTSPWTPVVTTSTQTKIRPNLPIPSTVLRKSGSATVSKPAPLNTFLSIKSSGTSTKPLPVVKESSSDLLLPPDIISKAFGGEEVVLKGSPEEKVELAEKNEPSQVPEQMLALLPPPPPPPPPPPPPPPPPPPQAVPQLSAPSPAQANVVLTPVKSNSVISQTFSLGFQGPNILNPGLPVAFMASEQPTVIPSDETAPGVSESDWDQTLISMLVRPPPPLSSVFSEQAKKLEKRNSCLATANAKDLYDIFYSSGGKGAHETKLSSSTLANGESSSLPRTESSDFSSTCTLNSSMSSEDLPQCSALVTATEISNLENPISKGMESTGKWSVVDQIDPKSRDSTYSFLQPLTRLYQNKPYEIVSPKTDTLVMWTSGSSQNDTHKDRPPEGKIRFDLGEPGPPGTDSTSHLSDTHCQTNGPQKLIEINLIDNQNKNQEVYQSEGCRESEMKRKTELKGKVATEEEEEEEEEGANSIEDSNSNHGNRNTWEGEIGQPKLSTVDKKGEQSSKLMTGHENTSKVVIELSPSLPSKRTKIDLFPSLLQNPKSMPELLLLSPAGSGLCLKRQEIWERPEKPGLEDVELQGTRPELTVTIESKVLENFDTTHLEVEGFASLRNLGDMHANFHNSQTEQTRRSPTALSEKMSEEISVSSVMCNPSSSSDIEPVPSFSGFPLESPKTLVLNFETEGAHSSSNSRNGRITSNSLETGHPVENVGHDLGGERTHQALDLLAGGMLSEDVKETSPLQKDLLRMESTTVSPSGLGPSPCLPDLVDFVTRTPGVPKQKPCSPLSEPDAFLKCSSLEMGSPPPEILSVSVSEVAVPQVSEDNDSALNLVKTPPSGSPSRDQVVGGNVSPREMPEQEAAVDVIPDHTRSNVYNSQDYLNG
Protein: Javelin-like, isoform A (Q9VFG3)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
MPTTKTQTQTTTTCSEEEEAAIIRENCDTPMATPANATTANTTTAAPITTTTTTVNTRRQEEAAAVASTPSVTKTATTTNILAAAAGCHKPLFFSRRFQDKRNFSSLPLFVYATSPSTHAHSADGVGVAKEAAAFCHKNEGFEPATHGISKTDGSCISHHSQSNGNGIEGVNGGGIVGHHLGGVLRTTDLASGAMECLPMSSAAHHPHLMAGASAVGAVSASPTATVVVGATYPHHLHHHHLSHHTPYSNSYGSHHIHSEQTKSLQELQHEVGALLEFRDLVIETFPDLKHKMASMSATPSTPTSSVGAIGGSHSVGGGSSSLATSRREWEPGIRMKRKQSHKEPSTSSAAAAPSSGAEASSSSLTRSRSNSHSGKKEPKSGENNNGSVVQDSGFSTETSSSKEGHSASSTNGAMTVAIAANRLSCAESDDELLNLLDVIHRKSNRLREEVEHLQSYERQHGDAQKTGGEGQGASKEGMTAQQFREQVERLNREDIKQLRKERDRLLDKLAEMEAETLTGRIKAAKMSDQVEELVGVKKDLEEQLKLAMAQKLELSSRVQQLQQQQQSKSSSSGSQSDYSSQRNFLSSATTVLSNGSRPSSNVISNNTFQPVVLDQPAQEAFHQSPGSDIPLRKQQQQSLGRLDGIVSTPGTRNSKCRLTDSKRFAAILLETNVLELQRHLLTLTVQNQVLAQKLESSSKSKTLLAKRLDKNSEEFEHLRYQLEEKNIELEGTKAQLRLVESRLQASNSTSNSYLHSSQHDYETNRSSASTTLMLSRRGVSDSVDSTSTAMPAPPVTQISTPSMKAMVPLAMDELQQHSSSTESAHEHENQGLQTPNSTSSPLSKTIINASPCPVGSSTPSNIAARVMSISVGGVSPFEAMTPPPRQNAFRKFGSASKPSKIPLPGSKAAAYFSGKPPTGRPSTAGRSPPSANNSSSTSYGSKSSLSRSTGNLQSLRRAETSASNHSLSTNTSRSSTSSSIPLATTPYSSGSTGNRSQPTAATTPSPRVLQNSPLPKLKRDTISSRVRHLDSLSRAQQTPEGLKGTTTNSTSIAAQLSSTLRKDLQLSGNGTGAPYNQHHLNHRRSGHSPASNSSGSGVSRRYSSASTGGSGGRAIGRDQGEPTTPTSSYGGDSDSGKIQATYPNKRQATLRK