wanglab/gogpt-training-data huggingface dataset:
Protein: Zona pellucida sperm-binding protein 3 (Sperm receptor) (Zona pellucida C protein) (Zona pellucida glycoprotein 3) (Zp-3) [Cleaved into: Processed zona pellucida sperm-binding protein 3] (P79762)
Organism: Gallus gallus (Chicken)
Function: Component of the zona pellucida, which mediates species-specific sperm binding. Directly binds to sperm. Important for egg fertilization.
Subcellular location: [Processed zona pellucida sperm-binding protein 3]: Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:10103002}. Note=The glycoproteinaceous translucent extracellular matrix that surrounds the mammalian oocyte is called zona pellucida. {ECO:0000305}.; SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:10103002, ECO:0000269|PubMed:20970175}; Single-pass type I membrane protein {ECO:0000255}.
Interaction partners:
- Uromodulin
- Zona pellucida protein
- Uncharacterized protein.
- ZP domain-containing protein.
Sequence:
MQGGRVVLGLLCCLVAGVGSYTPWDISWAARGDPSAWSWGAEAHSRAVAGSHPVAVQCQEAQLVVTVHRDLFGTGRLINAADLTLGPAACKHSSLNAAHNTVTFAAGLHECGSVVQVTPDTLIYRTLINYDPSPASNPVIIRTNPAVIPIECHYPRRENVSSNAIRPTWSPFNSALSAEERLVFSLRLMSDDWSTERPFTGFQLGDILNIQAEVSTENHVPLRLFVDSCVAALSPDGDSSPHYAIIDFNGCLVDGRVDDTSSAFITPRPREDVLRFRIDVFRFAGDNRNLIYITCHLKVTPADQGPDPQNKACSFNKARNTWVPVEGSRDVCNCCETGNCEPPALSRRLNPMERWQSRRFRRDAGKEVAADVVIGPVLLSADPGAVGQQEEGGDGAAVMVPSVGTGLVCVAVAVALAAVGVAVGIARKGCTRTSAAV
Protein: Iron transport multicopper oxidase fetC (EC 1.-.-.-) (Cell surface ferroxidase fetC) (E9R598)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Function: Cell surface ferroxidase; part of the reductive iron assimilatory system (RIA), a siderophore-independent high affinity iron uptake mechanism. Required to oxidize Fe(2+) and release it from the transporter (By similarity).
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P38993}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:P38993}; Extracellular side {ECO:0000250|UniProtKB:P38993}.
Interaction partners:
- High affinity iron permease ftrA
- Ferric/cupric reductase transmembrane component B
Sequence:
MAVGFLLLTAFVVNILTTSAATLHYDWNITWVTANPDGQFERPVIGINGQWPPPVLSFTRGDRIIAKVHNALGNETTSVHWHGFFQNGTNHMDGPPSVTQCDIAPGSTFVYNFTVEQSGTYWYHSHTKGQYPDGLRQALVVTDPKNPYIGQYDEERVISLSDWYHDQMPTLLKSFISISNPTGAEPVPKAALMNDTQNLTVAVEPGKTYLFHLVNVGAFASQYFWIEDHTMKIVEVDGVWTHASEANMIYIASAQRYSVLVTMKNETSQNYAMVGSMDTDLFDTLPESLNYNVTGWLMYNDQADKPTPALVSAFEPYDDFNLVPVDGMALHKEADYTVTLDVTMDNLGDGANYAFFNGITYVMPKVPTLYSVLTTGSAATDPAVYGYNTHPIVLKRGDIVDIVLNNDDAGKHPFHLHGHTFQVIARSEENAGHYDPSNHTTFPSIPMRRDTVIVRPQGNFVLRFQADNPGVWLFHCHIEWHMDSGLAATFIEAPLDLQKTLKIPEDHYQVCEASGTLTAGNAAGNTKDLFDLTGQNVSPAPLPAGFTAKGIVALVFSCVAAILGLLSIAWYGMAPITAPRAGSTPSNDSDEN
Protein: Tyrosine-protein kinase receptor (EC 2.7.10.1) (A0A0C4UR07)
Organism: Nilaparvata lugens (Brown planthopper)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
Sequence:
MFCRSRKKWGLLAGVRLTSVTVISTVIFILTCYETVSGRICPNTDVRNNISIMRTKLENCTVIEGSLHVVLIEKASENKFENVSFPLLREVTGFVLFYRVNYLRSIGQLFPNLSVIRGNHLFMNFALVIYEMRDLQEVGLYNLRTIVRGSVCIFKNTKLCYVNSVDWLSLSEMGWWIEHNKSPELCGRCPANCKHCWNAKRCQLTQQGDGAQLSDTGATVAGQLPEKCHPLCLGGCYGPSAHECVACRGVFTPDNMCVRQCPPGTVKWLERRCIYTETCQNHTTADPNIIKNNNDTNFFVFNGSCVHECPEGLEKGPNGCRQCTSSHCRKTCEGQVVDSLSAAQNLTGCTHIVGSLIISLKTGSDKFIQPELQQSLGSIQEIDGSLKIVRTFPLVSLNFLRNLRIIHGKKLLFNDNKSFVVAENHNLQELWDWNQRPSRLQILNGSVFFHYNPKLCLSLIKSFIKEINFTKTIGLLDISEESNGDKFPCKTVNLNVRVLKRYNESVELYIEKPKDKEMFSRYILYYVKSPFQNISYEEPDDCGDYGWKTKDISSDWKLDEPHNITYPITQLEPNTQYAFYVKTYTIDSFALKSGVQYFRTLPSKPTFPTKLTATSESSSSITLKWNPPSIANGKLEKYIVHGYKQKMDMAFYLNRDFCIYPLQYREVVITTPTVLPEVNQTTEFNETAISKYKDNSEKCVCEEKVKVEAIKSKQTHDNDDLQMFCDNSRSYKYLPNRALDIDKGFECEKSFFAALYERPFGNEGMRYNYNNIDIQGSSQSNADQKSINTQDNETHDRNIGIVDQLSEADEFVIDDNGQIARFFLHIPGNMTETKVENLPYFSEYTIEVRACREIDSEEPLESRSLASRCSFSSITTHRTQQNKTADFIPFVKHKIFNKTTAMFRWGKPANPNGIIVSYSFEYRSIDRSSSLHQTICVSIEEYNNNSKKGYNYKLENIPRGKYAYRIRALSMASEGEYTESSYFEIEEEFSFSFKLIFAVCFIMMTVFMIICSLYYWRKKPVVMFPDVNPEYQSIYNCRYVEDEWELCRENVEIVKELGKGTFGMVYEGILKPNNVPCAIKTVSARQNESEYFDFLLEASIMKSFSGSNHIIRLLGVVSRGTPPLVVMELMALGDLKMFLRSTRDSSLRPPPTGRTVLHMAAQIADGMAYLESKKFVHRDLAARNCMVADDLTVKIGDFGMTRDIYETDYYRKGTKGLLPIRWMAPESCYDGIFSSHSDVWSYGVVLWEISTLAEQPYQGKSNEEVLAYVLAGNSLQAPLFCPEVIKPIMLSCWNFRPTKRPSFLQIVNTLEPHTNDYFKTVSFFHSTEAIELRKNLKMYDYHNLNKMLLLSTLLNNEDTNEANSSSSHDSPSSSHSNLNNGSQHNYCIDDKDDNYVTGTNSPAVITENNDCSKNRRVLTNGQAHLTR
Protein: Probable glycine dehydrogenase (decarboxylating) subunit 1 (EC 1.4.4.2) (Glycine cleavage system P-protein subunit 1) (Glycine decarboxylase subunit 1) (Glycine dehydrogenase (aminomethyl-transferring) subunit 1) (Q72C59)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Function: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
Interaction partners:
- aminomethyltransferase
- glycine dehydrogenase
- Glycine cleavage system H protein
- 2-oxoglutarate dehydrogenase, E3 component, lipoamide dehydrogenase
- Serine hydroxymethyltransferase
- Threonine aldolase, low-specificity
- Aminotransferase, class V
- Phosphoribosylformylglycinamidine synthase I
- Glutamine synthetase, type I
- Glu/Leu/Phe/Val dehydrogenase family protein
Sequence:
MPFVPHSPEDVSVMLDAIGVNTIEDLFADIPAEMRPKSFALPKGLSEMDVCSRLEALSARNRTDVVSFLGAGFYDHHIPKAVDALSSRGEFYTAYTPYQPEAAQGTLQAIFEFQTAVCRLLDMDCANASVYDGGSALFEAMMMAVRATRRRKLVIDEALSPIYRTMLASYTSNLQLELVTVPHRDGLSDMDALKASVDDTCAAVVVQNPNFFGAITDFTDLFTHARAHKALGVISVYPVMQSVLKTPGEMGADIAVADGQSIGQPLSFGGPYLGIMTCTKPLVRQIPGRIVGRTQDVDGRTGYVLTLQAREQHIRRAKATSNICSNQALCALRSLIHLTLLGPEGLVRTAELSMERARYAAERLTALPGVELLHDAPFGNEFAVRLPVSAFEVVDRLTARGYVPGFPVGRYYPGMDNVLLVACTEKHSFEQVGILAEMLGGIL
Protein: Dehydration-responsive element-binding protein 2B (OsDREB2B) (Q5W6R4)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3' of the cis-acting dehydration-responsive element (DRE). Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription. Involved in drought and heat-shock stress tolerance.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00366, ECO:0000269|PubMed:20049613}.
Interaction partners:
- Os09g0110400 protein
- Histone H4
- Histone H4
- Actin-related protein 5
- Os06g0255200 protein
- Os02g0116900 protein
- Os07g0172500 protein
- FACT complex subunit SSRP1-A
- FACT complex subunit SSRP1-B
- Transcription elongation factor SPT4 homolog
Sequence:
MTVDQRTTAKAIMPPVEMPPVQPGRKKRPRRSRDGPTSVAETIKRWAELNNQQELDPQGPKKARKAPAKGSKKGCMKGKGGPENTRCDFRGVRQRTWGKWVAEIREPNQQSRLWLGTFPTAEAAACAYDEAARAMYGPMARTNFGQHHAPAASVQVALAAVKCALPGGGLTASKSRTSTQGASADVQDVLTGGLSACESTTTTINNQSDVVSTLHKPEEVSEISSPLRAPPAVLEDGSNEDKAESVTYDENIVSQQRAPPEAEASNGRGEEVFEPLEPIASLPEDQGDYCFDIDEMLRMMEADPTNEGLWKGDKDGSDAILELGQDEPFYYEGVDPGMLDNLLRSDEPAWLLADPAMFISGGFEDDSQFFEGL
Protein: Post-GPI attachment to proteins factor 3 (COS16 homolog) (hCOS16) (Gene coamplified with ERBB2 protein) (PER1-like domain-containing protein 1) (Q96FM1)
Organism: Homo sapiens (Human)
Function: Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins. Required for phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI.
Subcellular location: Golgi apparatus membrane {ECO:0000305|PubMed:12460457}; Multi-pass membrane protein {ECO:0000305|PubMed:12460457}. Endoplasmic reticulum membrane {ECO:0000305|PubMed:12460457}; Multi-pass membrane protein {ECO:0000305|PubMed:12460457}. Note=Mainly localizes to Golgi apparatus. {ECO:0000305}.
Interaction partners:
- StAR-related lipid transfer protein 3
- Acyltransferase PGAP2
- Migration and invasion enhancer 1
- GPI inositol-deacylase
- Growth factor receptor-bound protein 7
- Glucosaminyl-phosphatidylinositol-acyltransferase PIGW
- GPI alpha-1,6-mannosyltransferase 2
- GPI ethanolamine phosphate transferase 3, catalytic subunit
- Receptor tyrosine-protein kinase erbB-2
- Telethonin
Sequence:
MAGLAARLVLLAGAAALASGSQGDREPVYRDCVLQCEEQNCSGGALNHFRSRQPIYMSLAGWTCRDDCKYECMWVTVGLYLQEGHKVPQFHGKWPFSRFLFFQEPASAVASFLNGLASLVMLCRYRTFVPASSPMYHTCVAFAWVSLNAWFWSTVFHTRDTDLTEKMDYFCASTVILHSIYLCCVRTVGLQHPAVVSAFRALLLLMLTVHVSYLSLIRFDYGYNLVANVAIGLVNVVWWLAWCLWNQRRLPHVRKCVVVVLLLQGLSLLELLDFPPLFWVLDAHAIWHISTIPVHVLFFSFLEDDSLYLLKESEDKFKLD
Protein: Monolignol oxidoreductase AtBBE-like 13 (EC 1.1.99.-) (Berberine bridge enzyme-like 13) (AtBBE-like 13) (Q93ZA3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mediates oxidation of cinnamyl alcohol and of p-hydroxylated derivatives of cinnamyl alcohol (i.e. the monolignols p-coumaryl-, coniferyl-, and sinapyl alcohol) to their corresponding aldehydes. Can use cinnamyl alcohol and derivatives, as well as beta-O-glycosylated form of coniferyl alcohol (coniferin) as substrate.
Subcellular location: Secreted, cell wall {ECO:0000250|UniProtKB:O64743}.
Interaction partners:
- Aldehyde dehydrogenase family 2 member C4
- Peroxidase 68
- Peroxidase 15
- Peroxidase 67
- Peroxidase 57
- Peroxidase 55
- Peroxidase 1
- Peroxidase 3
- Cytochrome P450 84A1
- Putative beta-glucosidase 41
Sequence:
MAFVLMNNTNAFLVTLLLLSLSYIPLSFSTIQQDFVMCLVDNSDASFPMDSSFFTHDLNASSFKLALETSAQNLRYLMPSNPKPEFIFEPLYETHVQAAVLCAKKLKLHLRLRSGGHDYEGLSYVSEMETAFVIVDLSKLRQISVDIESNSAWVHAGASIGEVYYRIQEKSKIHGFPAGLCTSLGIGGHIIGGAYGSMMRKFGLGADNVLDARIVDADGKILNRAAMGEDVFWAIRGGGGGSFGVILAWKIKLVPVPEIVTVFTVTRTLEQDGTKLLYKWQQVADKLDEDLFIRVIIQPTSKTPKSKERTISTSYQGQFLGDANRLLQVMQRSFPQLGLTKKDCLETSWIKSVMYIAGFPSTAPSEALLDGKSLFKNYFKAKSDYVEEPIPVEGLEGLWEKLLEEDSPLTIWNPYGGMMAKIPETETPFPHRSGTLFKIQWLTLWQDGKTSEAKHMGWMREMYSYMEQYVSKSPRSAYVNYRDLDLGMNGKGSDAREWGNRYFKGNFERLVEIKAKFDPENFFRHEQSIPTELE
Protein: SH2B adapter protein 2 (Adapter protein with pleckstrin homology and Src homology 2 domains) (SH2 and PH domain-containing adapter protein APS) (O14492)
Organism: Homo sapiens (Human)
Function: Adapter protein for several members of the tyrosine kinase receptor family. Involved in multiple signaling pathways. May be involved in coupling from immunoreceptor to Ras signaling. Acts as a negative regulator of cytokine signaling in collaboration with CBL. Binds to EPOR and suppresses EPO-induced STAT5 activation, possibly through a masking effect on STAT5 docking sites in EPOR. Suppresses PDGF-induced mitogenesis. May induce cytoskeletal reorganization via interaction with VAV3.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:9989826}. Cell membrane {ECO:0000269|PubMed:9989826}. Note=Cytoplasmic before PDGF stimulation. After PDGF stimulation, localized at the cell membrane and peripheral region.
Interaction partners:
- Insulin receptor
- E3 ubiquitin-protein ligase CBL
- Growth factor receptor-bound protein 2
- High affinity nerve growth factor receptor
- BDNF/NT-3 growth factors receptor
- NT-3 growth factor receptor
- E3 ubiquitin-protein ligase CBL-B
- Insulin receptor substrate 1
- Tyrosine-protein kinase JAK2
- Mast/stem cell growth factor receptor Kit
Sequence:
MNGAGPGPAAAAPVPVPVPVPDWRQFCELHAQAAAVDFAHKFCRFLRDNPAYDTPDAGASFSRHFAANFLDVFGEEVRRVLVAGPTTRGAAVSAEAMEPELADTSALKAAPYGHSRSSEDVSTHAATKARVRKGFSLRNMSLCVVDGVRDMWHRRASPEPDAAAAPRTAEPRDKWTRRLRLSRTLAAKVELVDIQREGALRFMVADDAAAGSGGSAQWQKCRLLLRRAVAEERFRLEFFVPPKASRPKVSIPLSAIIEVRTTMPLEMPEKDNTFVLKVENGAEYILETIDSLQKHSWVADIQGCVDPGDSEEDTELSCTRGGCLASRVASCSCELLTDAVDLPRPPETTAVGAVVTAPHSRGRDAVRESLIHVPLETFLQTLESPGGSGSDSNNTGEQGAETDPEAEPELELSDYPWFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLTFNFQGKAKHLRLSLNGHGQCHVQHLWFQSVLDMLRHFHTHPIPLESGGSADITLRSYVRAQDPPPEPGPTPPAAPASPACWSDSPGQHYFSSLAAAACPPASPSDAAGASSSSASSSSAASGPAPPRPVEGQLSARSRSNSAERLLEAVAATAAEEPPEAAPGRARAVENQYSFY
Protein: Protein AAR2 homolog (AAR2 splicing factor homolog) (Q86P44)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
Sequence:
IIASEQYFTMNKDNSSMKMDPQLALRLLADGGVLVIAGVPEGTEFGIDLCAYTIGPDFRGVKMIPPGVHYVWCSSRGPYGDAAPRVGFVHFFHPNEIVVREWDHELEELRPRRIAEPEVERDRIRKNLAQLERVLAPYDYRYVVQWKELTGSVTESCVDRCRPTEGTIRTNIELQSCPDADRPRGGAATVSISRRNAAARILLDESELLPDLKPVEGTAPRFTTVPLRVPQDALPADVSRHALDCIDAVDKLLEGFETADGLIEELQLAYAFFLVGYSVESLAHWRKLLGLVAHSQTAVTKHKLTYMKYSEVLAHQLPHLPEELMVPGPHNTVYKDVRELLVNLHAGGLSVSAERLTKRLEKKLGWEFEGLLDEDPEDQPVVIELPEA
Protein: Chorismate mutase (CM) (EC 5.4.99.5) (TpARO7) (A0A0S0FTT9)
Organism: Trichoderma parareesei (Filamentous fungus)
Function: Catalyzes the Claisen rearrangement of chorismate to prephenate. Acts at the first branch point in the aromatic amino acid pathway where it steers biosynthesis towards phenylalanine and tyrosine, and away from tryptophan (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P32178}.
Interaction partners:
Sequence:
MDSAVDMADSERALNLTHIRFQLIRLEDTITFHLIERVQFPYNKTIYTPGAISIPDSKLSFFDWYFFQQEKLQSLIRRFESPDEYPYFPEAVQKPILKPLNYPKILHNNTVCVNDKIKKFYIEKFLPKVCPDFGREDRGEAQENYGSTSTCDIACLQALSRRIHFGKFVAESKFQSDPEYYTKLIQAEDREAIGESITNAAVEKQVLDRLRLKVETYGKDPSLLEGVEQPIKINVDAVVSMYKDFVIPLTKEVEVEYLMQRLIPEE
Protein: Uncharacterized protein YfcL (P64540)
Organism: Escherichia coli (strain K12)
Interaction partners:
- Elongation factor P lysine hydroxylase
- Probable membrane transporter protein YfcA
- Negative modulator of initiation of replication
- UPF0352 protein YejL
- Cell division protein ZapC
- Uncharacterized protein YheV
- Outer membrane protein assembly factor BamC
- Lipopolysaccharide export system protein LptC
- Penicillin-insensitive murein endopeptidase
- Chorismate synthase
Sequence:
MIAEFESRILALIDGMVDHASDDELFASGYLRGHLTLAIAELESGDDHSAQAVHTTVSQSLEKAIGAGELSPRDQALVTDMWENLFQQASQQ
Protein: Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o) (Q71DI3)
Organism: Homo sapiens (Human)
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular location: Nucleus. Chromosome.
Interaction partners:
- Histone H2A type 2-A
- Chromobox protein homolog 3
- Histone H2B type 2-E
- DNA
- Chromobox protein homolog 1
- Histone H2A type 2-C
- DNA
- Chromobox protein homolog 5
- Histone H4
- WD repeat-containing protein 5
Sequence:
MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
Protein: Type III effector HopU1 (Q88A91)
Organism: Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Interaction partners:
- HopF
Sequence:
MNINRQLPVSGSERLLTPDVGVSRQACSERHYSTGQDRHDFYRFAARLHVDAQCFGLSIDDLMDKFSDKHFRAEHPEYRDVYPEECSAIYMHTAQDYSSHLVRGEIGTPLYREVNNYLRLQHENSGREAEIDNHDEKLSPHIKMLSSALNRLMDVAAFRGTVYRGIRGDLDTIARLYHLFDTGGRYVEPAFMSTTRIKDSAQVFEPGTPNNIAFQISLKRGADISGSSQAPSEEEIMLPMMSEFVIEHASALSEGKHLFVLSQI
Protein: Zinc finger protein 212 (Q922Y8)
Organism: Mus musculus (Mouse)
Interaction partners:
Sequence:
MESNYETLVSLKVLGQPEEEVELGAEMVGDLVEEGTHLADRAMVKQEMLYKQEGPAGLPNMFSSAVEQQAFFGAEQAMFWNSPGDSALLESGPGDSNPESVETSRDPAPGRNLDCPRKQKSHRQVQLGQECGQGLKVKRDSSPYKCPECQISFRYKQQLTAHLQSHAGRESYSATEPEESLRPRPRLKPQAKRSKLHQCDVCHRSFSCKVSLVTHQRCHQQEGPSTSPQIQERFSPNSLVALPGHIPWRKSRSSLICGYCGKSFSHPSDLVRHQRIHTGERPYSCPECEKSFVQKQHLLQHQKIHQRERGGLASESARPNGLL
Protein: Altered inheritance of mitochondria protein 18, mitochondrial (Found in mitochondrial proteome protein 22) (P38884)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:14562095}.
Interaction partners:
- Putative uncharacterized protein YKL111C
- Uncharacterized protein YBR292C
- Non-structural maintenance of chromosome element 4
- Non-structural maintenance of chromosomes element 1
- Uncharacterized protein YGR161W-C
- Uncharacterized protein YOR020W-A
- Glutaredoxin-like protein YDR286C
- mRNA-binding protein PUF3
- Altered inheritance of mitochondria protein 11
- Probable transcriptional regulatory protein HAH1
Sequence:
MDRGRCANMLKSLQRTLAKCQKSPSTNHWQCFKRNFTSIRATKYPGRSNSTFHYWPWFAASTLLATSLYYRDRPVQNDDKTDAFPSHTESIQVDSSVSDFPLTITALNFPVSTTFKLLGYGQRHVTFLRFKVYALGLYLAENDENLVSDTLNETYLHKYFLDVDDSKTPKENLARLLKRDDSKSVMMIDDLLDSGMRMLAKITPVRNTDFKHLKEGLVKTISKHPDVANNKDTLAKGLSELNDAFSRKGSVRKNDDLIIELLANGALQFSYHDSKNNEFEVMGVVNNQLVGKFLFSQYLCGEKSPSPQAKKTAIDKLITLL
Protein: Betaine--homocysteine S-methyltransferase 1 (EC 2.1.1.5) (V9HWA4)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Interaction partners:
Sequence:
MPPVGGKKAKKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYASEDKLENRGNYVLEKISGQEVNEAACDIARQVADEGDALVAGGVSQTPSYLSCKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATMCIGPEGDLHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAARLKAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASGRPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFEKQKFKSQ
Protein: Uncharacterized ABC transporter ATP-binding protein C323.04 (Q9UT95)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Mitochondrion {ECO:0000269|PubMed:16823372}.
Interaction partners:
- Large ribosomal subunit protein bL33m
- ATP synthase subunit alpha
- Aspartate aminotransferase, mitochondrial
Sequence:
MASFVKFANTTFLDARFPLFKNVSFELARKQNWAIIGNTGSGRTTFLRCIQGSFTPSPSTSFSYPFLKGKSDSPWQAIQLLDFKSSGQQRAAYYSERYHSFRDKEHDTTLEKWLLGAYRGNEKFASQHVQEAASMTQLSHLLPSSLINLSNGQSRRAMLASKLVQRPQLLLLDEPYAGLDVTSRSVLSSLLGEMSNHCSPKIVLSLRPQDKIPDFITHVLELKNKKITYQGPKEQYIPMTSHSTNIPVKPQMKKSKPITIGKPLISMEHLNCVYWGRKVLSDINWTIREGERWALTGSNGSGKTTLLAYVVGDHPKLFASNIKFFGKSIGPGTGISIFDIQENIGHCSPEIHNHFPKQHTCFEALLSAWSTTFTIPKLTETRLAAISSILEEFELKDIKDKPLSSISVGMQRFILFCRAIVKQPRLVVLDEPFQGVDTKYVHMAHNYLNEKLSPSQAMVIISHYEDELPACVNRRAHIDNGKLVIHA
Protein: Large ribosomal subunit protein uL22c (50S ribosomal protein L22, chloroplastic) (P0C446)
Organism: Oryza sativa subsp. japonica (Rice)
Function: This protein binds specifically to 23S rRNA.
Subcellular location: Plastid, chloroplast.
Interaction partners:
- Small ribosomal subunit protein uS14c
- Os01g0348700 protein
- Os04g0501000 protein
- Large ribosomal subunit protein bL33c
- Os01g0220300 protein
- Large ribosomal subunit protein bL27c
- Os08g0116500 protein
- Os06g0683200 protein
- Os06g0319700 protein.
- 60S ribosomal protein L29
Sequence:
MTSFKLVKYTPRIKKKKSGLRKLARKVPTDRLLKFERVFKAQKRIHMSVFKVQRVLDEIRWRYYEETVMILNLMPYRASYPILKLVYSAAANATHYRDFDKANLFITKAEVSRSTIMNKFRPRARGRSSPIKKTMCHITIVLNIVKKSK
Protein: Protein ENDOPLASMIC RETICULUM-ARRESTED PEN3 (Protein ER-ARRESTED PEN3) (Q9S7R7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Confers resistance to soil-born pathogens (e.g. the root-penetrating fungus Fusarium oxysporum) by regulating membrane trafficking, specifically mediating ABCG36/PEN3 exit from the endoplasmic reticulum and subsequent relocalization at the host-pathogen interface of the plasma membrane.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:29085068}.
Interaction partners:
Sequence:
MVVSDGGKRVKLNVGGEIFETNASTIQSSCPDSLLAALSTSTSHGSNPVFIDRDPEIFAVILNLLRTGRLPANSSGVFSKQELLDEAMYYGVESLLRLAMLPPPLLGFDASLVSTIVPAADGVPSALTATAGDASLWIAHGGQISVYDWSLSHAGTVRTHLNDITSICRVWGEAAAIGSGSASGLHFYDLSGGRYIGSTHWTDPEDPRIHKARVAAVADSEGGVFASFDCLHRENSVLQIDKSTLQVAAVIGQQSGNSAKTTVPEKLRWLPAKGLLVGSAVQRGVFGCSGYIRIWDPRSRNIVWETNEPGSGRSTRFGDALADMDVDVEDSILFKVCSKSGDLGMADIRKLGEDPWVYMSDENPGAWKAGDGGGYSVVHCYRKQVLAARGGALEVWSSVKEKTSGDPIRRRNFVDKEDDSKRGMISKIEAGGDRLFVSRECMEGVEVWETSSFSGVVSVE
Protein: Aquaporin-8 (A0A060X7C2)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
- Aquaporin-4
- Aquaporin-9
- Aquaporin-9
- Aquaporin
- Aquaporin-7-like
- Katanin p60 ATPase-containing subunit A1 MIT domain-containing protein
- AAA ATPase AAA+ lid domain-containing protein
- Katanin p60 ATPase-containing subunit A1
- Uncharacterized protein
- Spastin/Vps4 C-terminal domain-containing protein
Sequence:
MGVEKMELDEGHSTLMSGTKKPPPVRPPNTFERIIQPCLAEVVGTMFFVFIGCVSVIENVESAGRVQPALVHGLAVAVMVACMDQISGSHFNPPFTIAIYLCGGMKLFMVVPYLISQLLGGVLGAAMSKMMTSKENYANATGAAFTILHTEDQLAGAIFGEIAMTCLVTMVVLLGAVNAKSKSPMVPFLVGCTVIINILAGGDVSGTCLNPARALGPAVMANYWTYHWVYWAGPITGGLLAAGLVRLVLGDEKTRVIMK
Protein: NEDD8-conjugating enzyme UBE2F (EC 2.3.2.34) (NEDD8 carrier protein UBE2F) (NEDD8 protein ligase UBE2F) (NEDD8-conjugating enzyme 2) (RING-type E3 NEDD8 transferase UBE2F) (Ubiquitin-conjugating enzyme E2 F) (Q969M7)
Organism: Homo sapiens (Human)
Function: Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.
Interaction partners:
- RING-box protein 2
- NEDD8-activating enzyme E1 catalytic subunit
- Ubiquitin-like protein NEDD8
- DCN1-like protein 3
- NEDD8-activating enzyme E1 regulatory subunit
- Cullin-5
- DCN1-like protein 1
- E3 ubiquitin-protein ligase RBX1
- DCN1-like protein 2
- DCN1-like protein 5
Sequence:
MLTLASKLKRDDGLKGSRTAATASDSTRRVSVRDKLLVKEVAELEANLPCTCKVHFPDPNKLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLLREHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVDDYIKRYAR
Protein: Titin (Q29117)
Organism: Sus scrofa (Pig)
Interaction partners:
Sequence:
CHKRLIGELRLRVTGLLENHNYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWGKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPVIVEEKMEAPDLDLDMELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDSTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVESLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAHTDDPVKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLEAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVRPGFNTYSVQAGQDLKIEVPVSGRPKPTITWTKDGLPLKQTTRINVTDSLDLTVLSIKETHKDDGGHYGITVANVVGQKTASIEIITLDKPDPPKGPVKFDEVSAESITLSWEPPLYTGGCQITN