wanglab/gogpt-training-data huggingface dataset:
Protein: Somatostatin receptor type 2 (SS-2-R) (SS2-R) (SS2R) (SRIF-1) (P34994)
Organism: Sus scrofa (Pig)
Function: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization (By similarity).
Subcellular location: Cell membrane; Multi-pass membrane protein. Cytoplasm {ECO:0000250}. Note=Located mainly at the cell surface under basal conditions. Agonist stimulation results in internalization to the cytoplasm (By similarity). {ECO:0000250}.
Interaction partners:
- Somatostatin
- G protein subunit alpha i3
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Somatostatin domain-containing protein.
- Appetite-regulating hormone
- Somatostatin receptor 1
- Pro-neuropeptide Y
- Endothelin-2
Sequence:
MDMAYELLNGSQPWLSSPFDLNGSVATANSSNQTEPYYDLTSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYAFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSVAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
Protein: Polymerase nucleotidyl transferase domain-containing protein (Q8IA66)
Organism: Caenorhabditis elegans
Interaction partners:
Sequence:
MSQPNKDQRSPEDIDFKVKANPKAFHKFNGKFQRVLRDHEDDFNILSISMQDHFDTTKQPKEEFGKKMDWCYQLKNIISKNNPTWLFNIVPTGSTVTGLATKNSDLDVAIHIPQAARVLEQEERGRNITDDERQASWREIQLEILQIVRLNLQNDEQINSRINWEHGIQLVQAQIQILKVMTVDGIDCDISVVMDRFLSSMHNSFLIRHLAHIDGRFAPLCAIVKQWAASTKVKDPKDGGFNSYALVLLVIHFLQCGTFPPILPNLQEIFKKDNFIAWDDKVYPSILNFGAPLPKPLPRIAPNNAPLARLFIEFLYYYSMFNFKENYIGARPVMVMDR
Protein: Choline-phosphate cytidylyltransferase A (EC 2.7.7.15) (CCT-alpha) (CTP:phosphocholine cytidylyltransferase A) (CCT A) (CT A) (Phosphorylcholine transferase A) (P49586)
Organism: Mus musculus (Mouse)
Function: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P19836}. Membrane {ECO:0000250|UniProtKB:P19836}; Peripheral membrane protein {ECO:0000250|UniProtKB:P19836}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P49585}; Peripheral membrane protein {ECO:0000250|UniProtKB:P19836}. Nucleus {ECO:0000250|UniProtKB:P49585}. Note=It can interconvert between an inactive cytosolic form and an active membrane-bound form. {ECO:0000250|UniProtKB:P19836}.
Interaction partners:
- Choline/ethanolaminephosphotransferase 1
- Choline kinase alpha
- Choline/ethanolamine kinase
- Cholinephosphotransferase 1
- Choline-phosphate cytidylyltransferase B
- Phosphoethanolamine/phosphocholine phosphatase
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 10
- Mitogen-activated protein kinase 9
- Stress-activated protein kinase JNK
Sequence:
MDAQSSAKVNSRKRRKEAPGPNGATEEDGIPSKVQRCAVGLRQPAPFSDEIEVDFSKPYVRVTMEEACRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALKHMLKEGKGRMLQAISPKQSPSSSPTHERSPSPSFRWPFSGKTSPSSSPASLSRCRAVTCDISEDEED
Protein: Plasmodium RESA N-terminal domain-containing protein (Q8IFM0)
Organism: Plasmodium falciparum (isolate 3D7)
Interaction partners:
Sequence:
MKFFNGSSFSNSNGFMDSKNLKNSAIFSFDEEEKKTASRSFLSSLLSKRMVIPMLGVLYVVLLNVCLHNGSNTSTNVQFNNNVGKRILSEGQSTDEYSESSSEYVENPVIGSTFMLPNENRLNTIGNLFEGEKYNILEDTQKLIDDINKFRYNSNYSPIPYPEQYNPVDYNKADFVLDKYIDNLGYCKGDTIKAMEIIWEATMNNERRKYAATKRSMLRYYDDLKRKRIIRPKTYTNKLNSCNQIMESSEKKIESHLSEMFNKWFKQKSLFLDDFNRFITACRIGWKTVSNAVQHQCDTIMRSKNFIDI
Protein: Vesicle-associated membrane protein-associated protein A (A8KA83)
Organism: Homo sapiens (Human)
Subcellular location: Cell junction, tight junction {ECO:0000256|ARBA:ARBA00004435}. Cell membrane {ECO:0000256|ARBA:ARBA00004521}; Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004521}. Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004163}; Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004163}.
Interaction partners:
Sequence:
MAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGIIDPGSTVTVSVMLQPFDYDPNEKSKHKFMVQTIFAPPNTSDMEAVWKEAKPDELMDSKLRCVFEMPNENDKLNDMEPSKAVPLNASKQDGPMPKPHSVSLNDTETRKLMEECKRLQGEMMKLSEENRHLRDEGLRLRKVAHSDKPGSTSTASFRDNVTSPLPSLLVVIAAIFIGFFLGKFIL
Protein: Protein Flattop (Cilia- and flagella-associated protein 126) (Q3SZT6)
Organism: Bos taurus (Bovine)
Function: Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear.
Subcellular location: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q6P8X9}. Cell projection, cilium {ECO:0000250|UniProtKB:Q6P8X9}. Apical cell membrane {ECO:0000250|UniProtKB:Q6P8X9}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:34715025}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q6P8X9}. Note=Localizes to the apical cell membrane, the basal body and the primary cilium in monociliated node cells (By similarity). {ECO:0000250|UniProtKB:Q6P8X9, ECO:0000269|PubMed:34715025}.
Interaction partners:
- Tektin-1
- Tektin-4
- Cilia and flagella associated protein 45.
- Outer dynein arm-docking complex subunit 1
- EF-hand domain-containing protein 1
- Cilia- and flagella-associated protein 276
- Sperm-associated antigen 8
- Tektin-3
- Cilia- and flagella-associated protein 52
- Cilia- and flagella- associated protein 210
Sequence:
MATNYSANQYEKPFSPKYLQNWSLAKPTKERISSHEGYTQIIANDRGHLLPSVPRSKASPWGSFMGTWQMPLKVPPARATLTSRTAAGAASLTRWIQKNPDLLKASNGLRPEIFGKPHDPDSQKKLRKSITKTVQQAPSPTIIPSSPASNLSSPDQLQSSHPSAGHTPGPQSPLNSPKCPPGSPCLPHAGRNLAEV
Protein: Multiple inositol polyphosphate phosphatase 1 (EC 3.1.3.62) (2,3-bisphosphoglycerate 3-phosphatase) (2,3-BPG phosphatase) (EC 3.1.3.80) (Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase) (Ins(1,3,4,5)P(4) 3-phosphatase) (O35217)
Organism: Rattus norvegicus (Rat)
Function: Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy (By similarity). Through the regulation of intracellular inositol polyphosphates, may control intracellular cation homeostasis, including that of calcium and iron, hence affecting free cation availability required for neural cell signaling (By similarity).
Subcellular location: Endoplasmic reticulum lumen {ECO:0000269|PubMed:8384201}. Secreted {ECO:0000250|UniProtKB:Q9UNW1}. Cell membrane {ECO:0000250|UniProtKB:Q9Z2L6}. Note=Also associated with the plasma membrane in erythrocytes. {ECO:0000250|UniProtKB:Q9Z2L6}.
Interaction partners:
- Inositol polyphosphate multikinase
- Inositol-trisphosphate 3-kinase A
- Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A
- Inositol polyphosphate 5-phosphatase K
- Inositol polyphosphate-5-phosphatase A
- Inositol-trisphosphate 3-kinase B
- Inositol-trisphosphate 3-kinase C
- Phosphoglycerate mutase 2
- Phosphoglycerate mutase 1
- Alpha-enolase
Sequence:
MLRGARSHLSASVALAAVLAAALLSSFARCSLPGRGDPVASVLSPYFGTKTRYEDVNPWLLGDPVAPRRDPELLAGTCTPVQLVALIRHGTRYPTTKQIRKLRQLQGLLQTRESVDGGSRVAAALDQWPLWYDDWMDGQLVEKGRQDMRQLALRLAALFPDLFCRENYGRLRLITSSKHRCVDSSAAFLQGLWQHYHPGLPPPDVSDMECDPPRVNDKLMRFFDHCEKFLTEVERNATALYHVEAFKTGPEMQTVLKKVAATLQVPVNNLNADLIQVAFFTCSFDLAIQGVHSPWCDVFDVDDAKVLEYLNDLKQYWKRSYGYAINSRSSCNLFQDIFLHLDKAVEQKQRSQPVSSSVILQFGHAETLLPLLSLMGYFKDKEPLTAYNFEEQVHREFRSGHIVPYASNLIFVLYHCEDAQTPQEKFQIQMLLNEKVLPLAHSQKTVALYEDLKNHYQDILQSCQTSKECNLPKVNITSDEL
Protein: Large ribosomal subunit protein eL14 (60S ribosomal protein L14) (A8K3Q9)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MVFRRFVEVGRVADVSFGPHAGKLVAIVDVIDQNRALVDGPCTQVRRQAMPFKCMQLTDFILKFPHSAHQKYVRQAWQKADINTKWAATRWAKKIEARERKAKMTDFDRFKVMKAKKMRNRIIKNEVKKLQKAALLKASPKKAPGTKGTAAAAAAAAAAAKVPAKKITAASKKAPAQKVPAQKATGQKAAPAPKAQKGQKAPAQKAPAPKASGKKA
Protein: LP20791p (Q9VL73)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Interaction partners:
- Histone RNA hairpin-binding protein
- Protein anoxia up-regulated
- Uncharacterized protein, isoform B
- FI03418p
- GH23506p
- Uncharacterized protein, isoform B
- Cuticular protein 78E
- LD44720p
Sequence:
MAEKVELLAQASMNGQQNDTRKVRKSPEFQPGVISRERSFVRTSNQQNINKRRSLAFNVPGNQTGQMRGKPAMDIYRPPNVRGELAAPAGGVGGDGPNGAIGGVANKLNVNAQEFTMTTSSGAPAEALGNRSSLILPLTNGPGVGVAPGLGPYGNVNRRQAGHSLGNMPGLKANHRSILVTYPINTGALSGQLPLMNSPSSGNILHTTNRVKFAPEPRGHKVASHNQFGQLNNNYAQPYQANINGVDPYMNGNALQRSKSLSSADALTRGMAGLGLGLGNEVADIGQFTPEIQALIDTALEDPNKLNSRCLMELTSQFIKRAVESRRFALPISRLCLNIIAREQKETFLEALLNTCRQWYQEREKLLFAIQGMKSPSRVRFTAFMAFLTEMFCQLKRRQLQLRTHHEGTPPPLVLLSLLSKCCGDCVRPPIRSLSEIECLFYVLTCIGQDMEQQLPQQLELLMSLVRDAFLNAGESAASIRRTLLQLIELKASHWQLPGNTVLYYTHTNN
Protein: Integrin subunit alpha 5 (A0A8I6A7G7)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
Interaction partners:
Sequence:
MGSWTPRSPRSPLHAVLLRWGPRRLPPLLPLLLLLWPPPLQVGGFNLDAEAPAVLSGPPGSLFGFSVEFYRPGRDGVSVLVGAPKANTSQPGVLQGGAVYVCPWGTSPIQCSTIQFDSKGSRILESSLYSEEPVEYKSLQWFGATVRAHGSSILACAPLYSWRTEKDPQNDPVGTCYLSTENFTRILEYAPCRSDFGSAAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQISESYYPQYLINPVQGQLQTRQASSVYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVTVLNGSDIHSLYNVSGEQMASYFGYAVAATDTNGDGLDDLLVGAPLLMERTADGRPQEVGRVYIYLQHPEGIEPTPSLTLTGQDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGEAQQGVVFIFPGGPGGLNTKPSQVLQPLWAAGHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKALVYRGRPIISASASLTIFPSMFNPEERSCSLEGNPVSCINLSFCLNASGKHVPNSIGFEVELQLDWQKQKGGVRRALFLASKQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHIALNFSLDPKAPMDSHGLRPVLHYQSKSRIEDKAQILLDCGEDNICVPDLQLAVYGEKKHVYLGDKNALNLTFLAQNLGEGGAYEAELRVTAPLEAEYSGLVRHPGNFSSLSCDYFAVNQSRQLVCDLGNPMKAGTSIWGGLRFTVPHLQDTKKTIQFDFQILSKNLNNSQSNMVSFPLSVEAQAQVSLNGVSKPEAVIFPVSDWNPQDQPQKEGDLGPAVHHVYELINQGPSSISQGVLEISCPQALEGQQLLYVTKVTGLNNCTSNYTPNSQGLELDPEVSPHHLQRREAPGRSSTTSGTQVLKCPEAKCFRLRCEFGPLHRQESRSLQLHFRVWAKTFLQEYQPFSLQCEALYEALKMPYQILPRQLPQKKLQVATAVQWTKAEGSNGVPLWIIILAILFGLLLLGLLIYVLYKLGFFKPNPPLSSNPPNLFKLCC
Protein: Biogenesis of lysosome-related organelles complex 1 subunit 1 (Protein acetyltransferase BLOC1S1) (Q1LXG2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Biogenesis of lysosomal organelles complex-1, subunit 2
- Biogenesis of lysosome-related organelles complex 1 subunit 6
- SNARE-associated protein Snapin
- Biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino.
- Dystrobrevin-binding protein 1b.
- Biogenesis of lysosome-related organelles complex 1 subunit 3
- Biogenesis of lysosome-related organelles complex 1 subunit 5
- Dysbindin-A
- BLOC-1-related complex subunit 8
- BLOC-1 related complex subunit 6
Sequence:
MLSRLLKEHQAKQNERKELQERRRREAIAAATCLTEALVDHLNVGVAQAYVNQRKLDHEVKTLQVQAGQFAKQTAQWINMVENFNQALKEIGDVENWARSIEMDMRTIATALEYVHKGPVQPAST
Protein: PR domain zinc finger protein 10 (EC 2.1.1.-) (PR domain-containing protein 10) (Tristanin) (Q9NQV6)
Organism: Homo sapiens (Human)
Function: May be involved in transcriptional regulation.
Subcellular location: Nucleus {ECO:0000269|PubMed:36440963}.
Interaction partners:
Sequence:
MDSKDESSHVWPTSAEHEQNAAQVHFVPDTGTVAQIVYTDDQVRPPQQVVYTADGASYTSVDGPEHTLVYIHPVEAAQTLFTDPGQVAYVQQDATAQQASLPVHNQVLPSIESVDGSDPLATLQTPLGRLEAKEEEDEDEDEDTEEDEEEDGEDTDLDDWEPDPPRPFDPHDLWCEECNNAHASVCPKHGPLHPIPNRPVLTRARASLPLVLYIDRFLGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKERDLHEDLWFELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYAASYAEFVNQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQPEQTTIPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRLELQNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEFAQLSNTIHTPLTTAVISATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQYIPVSQSASGLQQPQHIQLQVVQVASATSPHQSQQSTVDVGQLHDPQPYPQHAIQVQHIQVSGQPLSPSAQQAQQGLSPSHIQGSSSTQGQALQQQQQQQQNSSVQHTYLPSAWNSFRGYSSEIQMMTLPPGQFVITDSGVATPVTTGQVKAVTSGHYVLSESQSELEEKQTSALSGGVQVEPPAHSDSLDPQTNSQQQTTQYIITTTTNGNGSSEVHITKP
Protein: Probable chitinase 2 (EC 3.2.1.14) (Q9W092)
Organism: Drosophila melanogaster (Fruit fly)
Interaction partners:
- N-acetyl-D-glucosamine kinase
- beta-N-acetylhexosaminidase
- beta-N-acetylhexosaminidase
Sequence:
MTLRSRLSGEAPQLWLLLLLASTASSLWASVAARTGPLHDKVVVCYVSTWAVYRPEQGAYAIENFDPNLCTHVVYAFAGLDITQAAIKSLDPWQDLKEEYGKGGYEKMTGLKRSHPHLKVSLAIGGWNEGSANYSTLVANNLLRGRFVKQVSSFIRKYNFDGLDLDWEYPTQRKGKPADRENFVLLTKELREEFDEHGLLLTSAIGASKKVIDEAYDVRQISRYLDYLHIMCYDYHGSWDRRVGYNAPLTAPADDPLSVKFSIDYLLKLGAPPEKLVMGLPFYGRTFKTLASGFLNDVSEGVGFKGPYTREDGFLGYNEICQTLSNQTSGWTREWDPQTSQVLAKSERNVFTQEINVVTYDSSRSIANKVLFAMSKRLAGVMVWSVDTDDFLGNCKLDEDTYEDFQKVTAAPKRSSQNYPLLRTINEATMLAVDELAVPEPQPDDSENEIPHGSIADRKNAGASMVSLGLGVTAVFMLLHRLAQ
Protein: NAD(P)-binding Rossmann-fold superfamily protein (Q9SZ91)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Interaction partners:
- Serine/threonine-protein kinase RIO1
- Berberine bridge enzyme-like 19
Sequence:
MFLLKTWRSTAFGVYGYMNFTKSGFLDHSKKFKPEDMQLQIEGKNCVVTGANSGIGFAAAEGLASRGATVYMVCRNKERGQEALSKIQTSTGNQNVYLEVCDLSSVNEIKSFASSFASKDVPVHVLVNNAGLLENKRTTTPEGFELSFAVNVLGTYTMTELMLPLLEKATPDAKVITVASGGMYTSPLTTDLQFSGEKFDGVEQYARNKRIQVALTEKWADKYKNKGIGFYSMHPGWAETPGVAKSLPSFSESFAGKLRTSEQGADTIVWLALQPKEKLVSGAFYFDRAEAPKHLKLAGTSKSHDLIDSVIDSVHSMAALNP
Protein: Nap1l1 protein (Nucleosome assembly protein 1, like 1) (Nucleosome assembly protein 1-like 1) (Q803X7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Interaction partners:
- Ubiquitin conjugating enzyme E2 O.
- Histone H2A.V
- Histone H2A
- 40S ribosomal protein S6
- Importin 9.
- Chromobox homolog 1b
Sequence:
MDPADMEDVEEEEEDAGEDNSKARQLTRQMMQNPQILAALQERLDGLVGSPSGYMESLPKVVKRRVNALKNLQVKCAHIEAKFYEEVHELERKYAALYQPLFDKRSEIVRAAYEPTDEECEWKQDEEEELTVSKQEEMKEKAKVEEEKKDEEKEDPKGIPEFWLTVFKNVDLLSEMLQEHDEPILKHLQDIKVKFSDAGQPMSFTLEFHFEPNDFFTQTILTKTYKMRSEPDESDPFSFDGPEIMGCTGCTIDWTKGKNVTLKTIKKKQKHKGRGTVRTVTKTVPNDSFFNFFSPPEVPESGELDEDSEAVLAADFEIGHFIRERIVPRAVLYFTGEAIEDDDDDYDEEGEEADDEEGEEEADEENDPDYEPKKDANPPEECKQQ
Protein: O-phosphoseryl-tRNA(Sec) selenium transferase (EC 2.9.1.2) (Liver-pancreas antigen) (LP) (SLA-p35) (SLA/LP autoantigen) (Selenocysteine synthase) (Sec synthase) (Selenocysteinyl-tRNA(Sec) synthase) (Sep-tRNA:Sec-tRNA synthase) (SepSecS) (Soluble liver antigen) (SLA) (UGA suppressor tRNA-associated protein) (tRNA(Ser/Sec)-associated antigenic protein) (Q9HD40)
Organism: Homo sapiens (Human)
Function: Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
Subcellular location: Cytoplasm {ECO:0000305}.
Interaction partners:
- L-seryl-tRNA
- Selenide, water dikinase 2
- Selenide, water dikinase 1
- Serine--tRNA ligase, cytoplasmic
- serine--tRNA ligase
- Serine--tRNA ligase, mitochondrial
- tRNA selenocysteine 1-associated protein 1
- Selenocysteine-specific elongation factor
- Dynein axonemal light chain 1
- Selenocysteine insertion sequence-binding protein 2
Sequence:
MNRESFAAGERLVSPAYVRQGCEARRSHEHLIRLLLEKGKCPENGWDESTLELFLHELAIMDSNNFLGNCGVGEREGRVASALVARRHYRFIHGIGRSGDISAVQPKAAGSSLLNKITNSLVLDIIKLAGVHTVANCFVVPMATGMSLTLCFLTLRHKRPKAKYIIWPRIDQKSCFKSMITAGFEPVVIENVLEGDELRTDLKAVEAKVQELGPDCILCIHSTTSCFAPRVPDRLEELAVICANYDIPHIVNNAYGVQSSKCMHLIQQGARVGRIDAFVQSLDKNFMVPVGGAIIAGFNDSFIQEISKMYPGRASASPSLDVLITLLSLGSNGYKKLLKERKEMFSYLSNQIKKLSEAYNERLLHTPHNPISLAMTLKTLDEHRDKAVTQLGSMLFTRQVSGARVVPLGSMQTVSGYTFRGFMSHTNNYPCAYLNAASAIGMKMQDVDLFIKRLDRCLKAVRKERSKESDDNYDKTEDVDIEEMALKLDNVLLDTYQDASS
Protein: PH-sensitive chloride channel 1, isoform T (X2JCG3)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Interaction partners:
Sequence:
MGCVFEAAKEQPHKPRSRQLRRNQCRGKAEKAAAGTRGKVAVRGNNDKPAEDIKIKDNYQQNHKTQTETQTEVAAVVAIATDAGAETETETEAEAQKEPATGPEHLKAAAQVLLTIRQARQENNKHSSSQVAETHKDEGEDALARQGSIVDTAAGRIGIDIAATTIQVAERHEDGQHWQQHNVRRRRRQPDPAAHPASITKLSAISLHFHALAALAKTLQKHEDLSPVQDRQPLAYRAWQEHPYAETQMPATMSAAIIANVGATAAATSAAAFQYLGQHYKHYSQSISFYAASSVLLMLCYLTTASTAAATQSETGALDKHPIHGIDWSKFDESSSDKEILDLLLEKKRYDKRLLPPVNDEDFCCGLQSPDMATNQNARRPHNRGTLTVNVNVLLLSLASPDESSLKYEVEFLLNQQWNDPRLQYGNKSHYDFLNALHHHDSIWTPDTYFIMHGDFKDPIIPMHFALRIFRNGTITYAMRRHLILSCQGSLHIFPFDDPKCSFSMESISYEEAQIKYVWKNDEDTLRKSPSLTTLNAYLIKNQTTACDQNSWRGNYSCLRVDLIFTRDRAFYFTTVFIPGIILVTSSFITFWLEWNAVPARSMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRKRPLHNVVYRPGENPVTQFFKFTAVYQGEKRQNAGAPNEIVACTTCGGSNSPCTHSANNGCATETCFVQVRKKEPPHPIRVAKTIDVIARITFPTAYAIFLIFFFVHYKGFS
Protein: Galanin peptides [Cleaved into: Galanin; Galanin message-associated peptide (GMAP)] (P47212)
Organism: Mus musculus (Mouse)
Function: Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3 (By similarity). This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion (By similarity).
Subcellular location: Secreted {ECO:0000250|UniProtKB:P22466}.
Interaction partners:
- Galanin receptor type 1
- Galanin receptor type 2
- Galanin receptor type 3
- Somatostatin
- Pro-neuropeptide Y
- Pro-opiomelanocortin
- Protachykinin-1
- Prepronociceptin
- Pro-MCH
- Neurotensin/neuromedin N
Sequence:
MARGSVILLGWLLLVVTLSATLGLGMPAKEKRGWTLNSAGYLLGPHAIDNHRSFSDKHGLTGKRELQLEVEERRPGSVDVPLPESNIVRTIMEFLSFLHLKEAGALDSLPGIPLATSSEDLEKS
Protein: Tetratricopeptide repeat domain 1 (H0YB37)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
DKKEMAINDCSKAIQLNPSYIRAILRRAELYEKTDKLDEALEDYKSILEKDPSIHQAREACMRLPKQIEERNERLKEEMLGKLKDLGNLVLRPFGLSTENFQIKQDSSTGSWCLCSWCPRFWLSYVQEEAHLLRLTFLIIHTHSPAKASPEPNKPVGWETAQT
Protein: Thiocyanate methyltransferase 1 (EC 2.1.1.n4) (Protein HARMLESS TO OZONE LAYER 1) (AtHOL1) (Q0WP12)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: S-adenosyl-L-methionine-dependent methyltransferase. Involved in glucosinolate metabolism and defense against phytopathogens. Highly reactive to thiocyanate (NCS(-)) derived from myrosinase-mediated hydrolysis of glucosinolates upon tissue damage.
Interaction partners:
- Probable ubiquitin-conjugating enzyme E2 37
- Phosphorylase superfamily protein
- S-adenosyl-L-methionine-dependent methyltransferases superfamily protein
- At4g24340
- At5g01015
- At5g10830
- Small ribosomal subunit protein mL103
- F22F7.17 protein
- Pentatricopeptide repeat-containing protein At2g18520
- ATP-dependent protease La
Sequence:
MAEEQQNSDQSNGGNVIPTPEEVATFLHKTVEEGGWEKCWEEEITPWDQGRATPLIVHLVDTSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALAKANETYGSSPKAEYFSFVKEDVFTWRPTELFDLIFDYVFFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHVGGPPYKVDVSTFEEVLVPIGFKAVSVEENPHAIPTRKGKEKLGRWKKIN
Protein: Epididymis luminal protein 12 (Epididymis secretory sperm binding protein Li 53e) (V9HW83)
Organism: Homo sapiens (Human)
Interaction partners:
Sequence:
MSSSGTPDLPVLLTDLKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS
Protein: Colony stimulating factor 2 receptor subunit beta (G3V608)
Organism: Rattus norvegicus (Rat)
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Interaction partners:
- Granulocyte-macrophage colony-stimulating factor
- Interleukin-3
- Interleukin-3 receptor subunit alpha
- Colony stimulating factor 2 receptor subunit alpha
- Tyrosine-protein kinase JAK2
- Interleukin-5
- Interleukin-5 receptor subunit alpha
- GTPase NRas
- GTPase HRas
- Tyrosine-protein kinase
Sequence:
MDQHMAFIWGLCYMALVALCWRHGVTKAEETVPLKTLQCYNDYIERIICSWADTEDAQGLVNLTLYHWLDKKQPMSCELSEDLMWSECPSSHRCVPRRCVLPYTQFSVSKEDYYSLQPDRDLSIHLVVPLAQHVQPPPPKDISISPSGDHFLLKWSVPHGDAQVSLLSQKDIQFEVAYKRLQDSWEDASSLHTSNLWVTLEPKLFLPNSIYVARVRTQLAPGSSLSGRPSRWSPEVHWDSPTGDKARPQNLQCFFDGIQSLNCSWEVWTKVTDSVSFGLFYSSSPKAGEKKCSPVVKELQASRYTRYHCSLNVSDPAAHSQYTVSVKRLEQGKFIESFNHIQMNPPTLNLTKNRDSYSLHWETQKMSYPFIQHAFQVQYKKKLDSWEDSKTENLNHAHSMDLPQLEPGTSYCARVRVKTIPEYKGLWSEWSNECTWTTDWVMPTLWIVLILVFLILTFLLALRFGCIYGCKLYRKWKEKIPNPSKSLLFQDGGKGLWPPGSTVTFSSKNPTPQGPQSNLFSELQGVSYTHLEDNEVSPLTIEDPNIIRDPSSGPDTTPAASSEPMEQSSNVQVDPPTLSGRPRKQLPSFDFNGPYLGPPQSHSLPDLPGQLVSPQGGGSLKPALPGSLEYMCLPPGGQVQLVPLSQVMGQGRDVDVQCGSSLETTESPSMESRESPPVELKEEEQEPRDNPVTLPISSGGPKDSKVASEYVTPADLVLTLPTEPLSTSLGPSLEVSSAQSPSLCLKLPRVPSESPALAPAVFEDYVELPPSMSQPAKSLPGNPAPPGPSSPAVSPGEPREEVGAAPTHPEGLLVLQQVGDYCFLPGLGPSPLSPPSKPPSPGLCLETEDLDKDLSVKKLPYQPIPQVPAIQFFKSLKHQDYLSLPPWDNSQPGKVC
Protein: Probable semialdehyde dehydrogenase (Q9I491)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Interaction partners:
- Probable dihydrodipicolinate synthetase
- 2,5-dioxovalerate dehydrogenase
- Bifunctional trans-3-hydroxy-L-proline dehydratase/2-epimerase
- 2-oxoglutarate dehydrogenase E1 component
- Isocitrate dehydrogenase
- Isocitrate dehydrogenase
- 4-hydroxyproline 2-epimerase
Sequence:
MPSILGHNYVGGARSAAGNLTLRSLDADSGEALPYAFVQATEAEVDAAARAAERAYPHYRQLSATRRAGFLEAIASRLDALGDDFVALVRRETALPAARIEGERTRTANQLRLFAEVLRRGDFHGVRIDRGQPGRTPPRPDLRQWRIGLGPVAVFGASNFPLAFSTAGGDSAAALAAGCPVVVKAHGGHMATAECVADAILQAAADSGMPDGVFNMVYGSGVGEALVRHPAIRAVGFTGSLKGGRALCDLAAARPQPIPVFAEMSSINPLVVLPEALRRRGRQVAEELAASVTLGCGQFCTKPGLVLGLRSPGFDAFVAALGEALAARPAQSMLNAGTLRSYVEGLQRLERHPGIRRLAGAPQEGRQAHPQLFKADVGLLLEGDELLQEEVFGPATVVVEAADEEQLARALDNLHGQLSATLIGEADDLAAFAGLVPLLERKAGRLLFNGYPTGVEVCDAMVHGGPYPATSDARGTSVGTLAIERFLRPLCYQDYPDSLLPDALKNANPLGLLRLVDGRSTREALD