wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Retromer subunit (A0A1D8PJS7)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Sequence: MSIFFKAPLDIEIRLDNEDTRKHVEVKTPQGRVEKLPIYKDGESVKGVVTLRTKEGRKLEHLGVRVQLLGSIETNTDGISSSEFLTLATELAAPAQLSHPESYPFEFKNVEKQYESYRGKNVRLRYYIKVTVLRKSSSEIIREKELWVYHYTTAVPKPVTGLSSSSTADSKLGAKKANEDTLQKPATPSSNDDASANTSKGSTISKRNESHSVKMDVGIENCLHIEFEYSRSRFSLTDAIIGKIYFLLVRLKIKHMELSLIRRETVGAPPNQVTDSETVVRFEIMDGAPVKGETIPIRLFLSGFDLVPTYRDVNKKFSTRTYLSLVLIDEDARRYFKQSEIILYRDQ
InterPro domains: - IPR028934: Vacuolar protein sorting protein 26 related (family) [1-346]
- IPR014752: Arrestin-like, C-terminal (homologous_superfamily) [1-347]
Interaction partners: - Vacuolar protein sorting-associated protein 29
- Vacuolar protein sorting-associated protein 35
- Sorting nexin-3
- Sorting nexin 1
- Vacuolar protein sorting-associated protein 17
- Type I sorting receptor
- Oxidant-induced cell-cycle arrest protein 5
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0140318 (protein transporter activity), GO:0008320 (protein transmembrane transporter activity), GO:0022884 (macromolecule transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0030447 (filamentous growth), GO:0006950 (response to stress), GO:0009607 (response to biotic stimulus), GO:0007154 (cell communication), GO:0009991 (response to extracellular stimulus), GO:0031668 (cellular response to extracellular stimulus), GO:0044182 (filamentous growth of a population of unicellular organisms), GO:0036180 (filamentous growth of a population of unicellular organisms in response to biotic stimulus), GO:0042594 (response to starvation), GO:0071496 (cellular response to external stimulus), GO:0033554 (cellular response to stress), GO:0036170 (filamentous growth of a population of unicellular organisms in response to starvation), GO:0009267 (cellular response to starvation), GO:0031669 (cellular response to nutrient levels), GO:0031667 (response to nutrient levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0098796 (membrane protein complex), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0030904 (retromer complex), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)
Protein: Amino acid ABC transporter (A0A0H2UQP0)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Function: Not known
Sequence: MREIMLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQAHLYDMIMIGVLVVPVLSFAVMSLILVFKA
InterPro domains: - IPR025134: Protein of unknown function DUF4059 (family) [5-76]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0046907 (intracellular transport), GO:0045184 (establishment of protein localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0008104 (protein localization), GO:0015031 (protein transport), GO:0006605 (protein targeting)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: CSN8/PSMD8/EIF3K domain-containing protein (Q4Q557)
Organism: Leishmania major
Function: Not known
Sequence: MTRDDGTQVAQLLSEGKYNLPMFLRYLKASSMEGDQPDKSLLLGILLQSLARFQTSDFTACMCLVPSHVQDSPSVEKELNYIYGLENLLSCGLFARFWTQWSSVKEHLPESFHFEARVRTSILETICITMESIPTEKLATYLAVSPDQVQKVVHNAMKDSEDRDMKVMAYDSGSVVFHRNRFNYPQAGAAQDAIRFTDVSSVIHNDVPRRGAAVAADETRDVRARTWARMADE
InterPro domains: - IPR016024: Armadillo-type fold (homologous_superfamily) [9-108]
- IPR009374: Eukaryotic translation initiation factor 3 subunit K (family) [8-204]
- IPR033464: CSN8/PSMD8/EIF3K (domain) [44-154]
- IPR016020: Translation initiation factor 3, subunit 12, N-terminal, eukaryotic (homologous_superfamily) [6-100]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [106-208]
Interaction partners: - Eukaryotic translation initiation factor 3 subunit I
- Putative translation initiation factor
- Eukaryotic translation initiation factor 3 subunit 7-like protein
- Eukaryotic translation initiation factor 3 subunit L
- Eukaryotic translation initiation factor 3 subunit E
- RRM domain-containing protein
- Putative eukaryotic translation initiation factor 3 subunit 8
- Uncharacterized protein
- Putative 40S ribosomal protein S15
- Putative 40S ribosomal protein S10
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0008233 (peptidase activity), GO:0004175 (endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0044248 (cellular catabolic process), GO:0009057 (macromolecule catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0006508 (proteolysis), GO:0044265 (cellular macromolecule catabolic process), GO:0030163 (protein catabolic process), GO:0043632 (modification-dependent macromolecule catabolic process), GO:0010498 (proteasomal protein catabolic process), GO:0051603 (proteolysis involved in protein catabolic process), GO:0019941 (modification-dependent protein catabolic process), GO:0043161 (proteasome-mediated ubiquitin-dependent protein catabolic process), GO:0006511 (ubiquitin-dependent protein catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005852 (eukaryotic translation initiation factor 3 complex), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm)
Protein: D-cysteine desulfhydrase (EC 4.4.1.15) (P76316)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine. Can also catalyze the degradation of 3-chloro-D-alanine.
Sequence: MPLHNLTRFPRLEFIGAPTPLEYLPRFSDYLGREIFIKRDDVTPMAMGGNKLRKLEFLAADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTTAENYLTNGNRLLLDLFNTQIEMCDALTDPNAQLEELATRVEAQGFRPYVIPVGGSNALGALGYVESALEIAQQCEGAVNISSVVVASGSAGTHAGLAVGLEHLMPESELIGVTVSRSVADQLPKVVNLQQAIAKELELTASAEILLWDDYFAPGYGVPNDEGMEAVKLLARLEGILLDPVYTGKAMAGLIDGISQKRFKDEGPILFIHTGGAPALFAYHPHV
InterPro domains: - IPR005966: D-cysteine desulfhydrase (family) [12-328]
- IPR023702: D-cysteine desulphhydrase, bacterial (family) [1-328]
- IPR036052: Tryptophan synthase beta chain-like, PALP domain superfamily (homologous_superfamily) [7-326]
- IPR001926: Tryptophan synthase beta chain-like, PALP domain (domain) [16-316]
- IPR027278: 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase (family) [2-328]
Interaction partners: - L-cystine transport system permease protein TcyL
- L-cystine-binding protein TcyJ
- L-cystine transport system ATP-binding protein TcyN
- Cystathionine beta-lyase MetC
- Protein MalY
- 3-mercaptopyruvate sulfurtransferase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0016829 (lyase activity), GO:1901363 (heterocyclic compound binding), GO:0043168 (anion binding), GO:0019842 (vitamin binding), GO:0070279 (vitamin B6 binding), GO:0016846 (carbon-sulfur lyase activity), GO:0030170 (pyridoxal phosphate binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0009056 (catabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044282 (small molecule catabolic process), GO:1901575 (organic substance catabolic process), GO:0006790 (sulfur compound metabolic process), GO:0044248 (cellular catabolic process), GO:0006082 (organic acid metabolic process), GO:0016054 (organic acid catabolic process), GO:0044273 (sulfur compound catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0000096 (sulfur amino acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0000098 (sulfur amino acid catabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0046395 (carboxylic acid catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm)
Protein: S-layer protein (Parasporal protein) (Q9ZES5)
Organism: Bacillus thuringiensis subsp. finitimus
Function: The S-layer is a paracrystalline mono-layered assembly of proteins which coat the surface of bacteria.
Subcellular location: Secreted, cell wall, S-layer.
Sequence: MAKTNSYKKVIAGTMTAAMVAGVVSPVAAAGKSFPDVPADHWGIDSINYLVEKGAVTGNDKGMFEPGKELTRAEAATMMAQILNLPIDKDAKPSFADSQGQWYTPFIAAVEKAGVIKGTGNGFEPNGKIDRVSMASLLVEAYKLDTKVNGTPATKFKDLETLNWGKEKANILVELGISVGTTADKWEPKKTVTKAEAAQFIAKTDKQFGTEVAKVESAKAVTTQKVEVKFSKAVEKLTKEDVKLANKANNDKVLVKDVKLSEDKKSATVELYSNLAAKQTYTVDVNKVGKVEVTVGSLEAKTIEMADQTVVADEPTALKYTVKDENGTEVVSPAGIEFVTPAAEKINAKGEITLAKGTSTTVKAVYKKDGKVVAESKEVKVSAEGTAVASISNWTVAAEKADFTSKDFKQNDKVYEGDNVSVQVELKDQFNNVVNNVKAEYESLNTEVAVVDKATGKVTVLSAGKAPVKVTVKDSKGKELVSKTVEIEAFAQKAMKEIKLEKTNVALSTKDVTDFKVKAPVLDQYGKEFAAPVEVKVLDKDGKELKEQKLVAKYENKELVLNAHGQEAGKYTVELTAKSGKKEVKSKLALELKAPGVFSKFDVRGLENELDKYVTEENKKNEMVVSVLPVDANGLVLREKEAATLKVTTTDKDGKVVDATSGQVAVNDAAGTITVGNEAKAGETYKVTVVADGKLITTHSFKVVDTAPAAKKLAVDFTSTSLNEVAQGSELKTALLNILSVDGVPATTAGATVTDVKFVSADTNVVSEETAKFGTKGSTSIFVKELTVKKGEQTQKVELDKPVRVDVSIKEVKEVK
InterPro domains: - IPR003343: Bacterial Ig-like domain, group 2 (domain) [402-482]
- IPR014755: Copper resistance protein CopC/internalin, immunoglobulin-like (homologous_superfamily) [214-302]
- IPR051465: Cell Envelope Structural Component (family) [7-295]
- IPR032812: SbsA, Ig-like domain (domain) [217-287]
- IPR008964: Invasin/intimin cell-adhesion fragments (homologous_superfamily) [435-477]
- IPR001119: S-layer homology domain (domain) [30-215]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0044403 (biological process involved in symbiotic interaction), GO:0051701 (biological process involved in interaction with host), GO:0044406 (adhesion of symbiont to host), GO:0044650 (adhesion of symbiont to host cell)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005618 (cell wall), GO:0009274 (peptidoglycan-based cell wall)
Protein: Peroxidase 4 (Atperox P4) (EC 1.11.1.7) (ATP46) (Q9LE15)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.
Subcellular location: Secreted {ECO:0000255|PROSITE-ProRule:PRU00297}.
Sequence: MAIFKILVLLLSLCCFSQAQLSPTFYDQTCQNALSTIRSSIRTAISRERRMAASLIRLHFHDCFVNGCDASVMLVATPTMESERDSLANFQSARGFEVIDQAKSAVESVCPGVVSCADIIAVAARDASEYVGGPRYDVKVGRRDSTNAFRAIADRDLPNFRASLNDLSELFLRKGLNTRDLVALSGAHTLGQAQCLTFKGRLYDNSSDIDAGFSSTRKRRCPVNGGDTTLAPLDQVTPNSFDNNYYRNLMQKKGLLESDQVLFGTGASTDSIVTEYSRNPSRFASDFSAAMIKMGDIQTLTGSDGQIRRICSAVN
InterPro domains: - IPR010255: Haem peroxidase superfamily (homologous_superfamily) [20-315]
- IPR019794: Peroxidase, active site (active_site) [52-63]
- IPR019793: Peroxidases heam-ligand binding site (binding_site) [180-190]
- IPR002016: Haem peroxidase (domain) [20-315]
- IPR033905: Secretory peroxidase (domain) [20-314]
- IPR000823: Plant peroxidase (family) [19-313]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0001666 (response to hypoxia), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0070482 (response to oxygen levels), GO:0071456 (cellular response to hypoxia), GO:0071453 (cellular response to oxygen levels), GO:0036293 (response to decreased oxygen levels), GO:0036294 (cellular response to decreased oxygen levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Mechanosensory protein 2 (Q27433)
Organism: Caenorhabditis elegans
Function: Subunit of an amiloride-sensitive cation channel (degenerin channel complex) permeable for sodium, potassium, lithium and N-methylglucamine, and required for mechanosensory transduction (touch sensitivity). Positively regulates the activity of the putative mechanosensory transduction channel. May link the mechanosensory channel and the microtubule cytoskeleton of the touch receptor neurons. Required for the function of a set of six touch receptor neurons.
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Sequence: MSATMSSARNSVVSLSSNGSVKVETRLVSNERSSSIQQEGAMLPSSSSKDDDLLSTSSDEVENMATRTLQQLEESTSIISANSDDDSVKKEKQAEKDVEKGNGKEEKANIQNEFGVCGWILTILSYLLIFFTLPISACMCIKVVQEYERAVIFRLGRLMPGGAKGPGIFFIVPCIDTYRKVDLRVLSFEVPPQEILSKDSVTVAVDAVVYFRISNATISVTNVEDAARSTKLLAQTTLRNILGTKTLAEMLSDREAISHQMQTTLDEATEPWGVKVERVEVKDVRLPVQLQRAMAAEAEAAREARAKVIVAEGEQKASRALKEAAEVIAESPSALQLRYLQTLNSISAEKNSTIIFPFPIDLLSAFLQRTPPKVEEPPSLPKKIRSCCLYKYPDWVQGMVGSEGGGGHGHSHGGGGGGLGSSQGAFHPSQAGSGPSTTTTSGRPLLRSMREAQFHSAAPPISAPNQSQTSVSQLDPALLIR
InterPro domains: - IPR001107: Band 7 domain (domain) [139-314]
- IPR001972: Stomatin/HflK family (family) [146-341]
- IPR043202: Band-7 stomatin-like (family) [71-374]
- IPR018080: Band 7/stomatin-like, conserved site (conserved_site) [254-282]
- IPR036013: Band 7/SPFH domain superfamily (homologous_superfamily) [172-305]
Interaction partners: - Degenerin mec-4
- Degenerin mec-10
- Mechanosensory abnormality protein 6
- Kunitz/Bovine pancreatic trypsin inhibitor domain protein
- MEC-5
- Tubulin alpha-3 chain
- AMP-binding domain-containing protein
- Papilin
- Band 7 domain-containing protein
- Tubulin beta-1 chain
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0007610 (behavior), GO:0007638 (mechanosensory behavior), GO:0009612 (response to mechanical stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0031252 (cell leading edge), GO:0031256 (leading edge membrane), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0098590 (plasma membrane region), GO:0120025 (plasma membrane bounded cell projection), GO:0032589 (neuron projection membrane), GO:0005886 (plasma membrane), GO:0043005 (neuron projection), GO:0031253 (cell projection membrane)
Protein: Candida glabrata strain CBS138 chromosome M complete sequence (Q6FJ18)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Function: Not known
Sequence: MIGGKSSPKSMKNSIGSTLRKWRSTLRKVTHDTLNSLDEVTANEEKIDALFDGEGGKTVNWGPVRTSKNGLVQVHEEDMLEEDVTNDLKSSSFGFEKSTTAQPVGIQGLLKSGSIEQISSGSRSLVGGVGGTSMRLSEESEEGGSTTGTSNKHEQLTIMKSSSGGSQGVSHKEKLTYDNFDAVAECNKLRQRSDKPFVGGPKIWEKRRKLWCEPSVSAEEIAHRRENGRGVFDAIPEAYHTSVYKKLVVDNKPLKEPLNLSHAMKVINAGWIDTKKWANAGKGLP
InterPro domains: - IPR053969: Gag1-like, lock domain (domain) [9-51]
- IPR025124: Gag1-like, clamp domain (domain) [197-277]
- IPR053274: Fluconazole resistance-associated protein (family) [9-284]
Interaction partners: - Nucleoporin NSP1
- Candida glabrata strain CBS138 chromosome G complete sequence
- Protein kinase C-like 1
- Candida glabrata strain CBS138 chromosome D complete sequence
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0051703 (biological process involved in intraspecies interaction between organisms), GO:0048878 (chemical homeostasis), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0019222 (regulation of metabolic process), GO:0071554 (cell wall organization or biogenesis), GO:0044010 (single-species biofilm formation), GO:0098743 (cell aggregation), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0098630 (aggregation of unicellular organisms), GO:0080090 (regulation of primary metabolic process), GO:0071555 (cell wall organization), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0098743 (cell aggregation), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0042710 (biofilm formation), GO:0051252 (regulation of RNA metabolic process), GO:0044011 (single-species biofilm formation on inanimate substrate), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0090605 (submerged biofilm formation), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: TCP pilus virulence regulatory protein (A5F384)
Organism: Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)
Function: Probable regulatory protein for the tcp operon.
Subcellular location: Cytoplasm {ECO:0000250}.
Sequence: MIGKKSFQTNVYRMSKFDTYIFNNLYINDYKMFWIDSGIAKLIDKNCLVSYEINSSSIILLKKNSIQRFSLTSLSDENINVSVITISDSFIRSLKSYILGDLMIRNLYSENKDLLLWNCEHNDIAVLSEVVNGFREINYSDEFLKVFFSGFFSKVEKKYNSIFITDDLDAMEKISCLVKSDITRNWRWADICGELRTNRMILKKELESRGVKFRELINSIRISYSISLMKTGEFKIKQIAYQSGFASVSYFSTVFKSTMNVAPSEYLFMLTGVAEK
InterPro domains: - IPR055025: ToxT, N-terminal cupin-like domain (domain) [5-162]
- IPR018062: HTH domain AraC-type, conserved site (conserved_site) [221-263]
- IPR020449: Transcription regulator HTH, AraC- type, HTH domain (domain) [236-267]
- IPR044875: ToxT, HTH1 motif superfamily (homologous_superfamily) [165-211]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [220-266]
- IPR018060: AraC-like, DNA binding HTH domain (domain) [172-269]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0090304 (nucleic acid metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0010467 (gene expression), GO:0018130 (heterocycle biosynthetic process), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0016070 (RNA metabolic process), GO:0032774 (RNA biosynthetic process), GO:0097659 (nucleic acid-templated transcription), GO:0006351 (DNA-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0032993 (protein-DNA complex)