Protein: FHA domain-containing protein PS1 (Protein PARALLEL SPINDLE 1) (AtPS1) (B7SY83)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for normal spindle orientation at male meiosis II and normal formation of tetrad of microspores. Not involved in female meiosis.
Sequence: MEVKEEKLMEEKQRLPEKTIPVFTVLKNGAILKNIFVVNSRDFSSPERNGSTVSDDDGEVEEILVVGRHPDCDILLTHPSISRFHLEIRSISSRQKLFVTDLSSVHGTWVRDLRIEPHGCVEVEEGDTIRIGGSTRIYRLHWIPLSRAYDLDNPFVSPLDASTVLEQEEENRMLEAENLEVAQHQSLENTTSGDEGVLHLDVTSEGTGSSVPSEDEDTYVTTREMSMPVASPSVLTLVRDSVETQKLQFNEDLQTSPKWDLDVIESVAEKLSGSFVRSTQQSGGDVEGLGCSELFDAAEADECDVRGDGGLHLNVISEKMESSVPNMIEAENLEVAQHQSLANTALGDDEDLHLDVTSEGTGSSVPSEDEDTYITTMEISVPLASPNVLTLARDSIKTQKLQSTQDFQTPTMWDLDVVEAAAEKPSSSCVLGKKLSGGYVEELGCFELFVAAEADKCDVRGDGSLHLNEISERMESSMSNKEDDPFLAAKETSSLPLSTDFINPETLWLVEDVQASPEFCTSSVKANAENPSSGCSPSTEQIDGCFETSGCSAFDLAAEVESLSLHQEVSEETEFVTKEVMGVSSEPLGKADIRSHEENGESEDSRQVIEVSAEPVAKADIQSHEENGETEGSRQVIEVSPKSFSEAEPTIEILTGEAQGIIGSEFPSELAVETESENLLHQKSIGETKNEIRSHEDYGETEDYGETECSWPDIAVSPSSVSPPEPTLEILTDEARGLLGSEFLSEVTVETEIENLLHQKSNVETKADILIHEDYGETEVSRQIITVSPNSFSKAEPTLETEDSRQQARGLVGSDSEFQSEVAMKTECENLLNQKRNGETKVSSRQASPVSDCLSTPKDRLSSINTDDIQSLCSSSQPPSESEVNPATDQDQESGIISETEKPKTELLIGSGRSEKYYSLSEIEGEENTDIGRLSRCPIPSALAAKTSEDTKLIEELSSSDSGSQENQTPETHAVRDDVLCDMDSSSTCNIWSRRGKAASVLKIRTNKSQGKQKQTGRQPKDKLHRKQALSDKSISLTIHHGAEILEPEIFTPDKENLTPSSHMLKRLQDIGDVKDSKSSLKLSGKSCSSLVHSSIAVLASEAFTEPEIFTPDKENLTPSSHMLKRLREFGDIKDTKGSSSKATRKPFFDIRMEENVMVEQEPEDLHSLGSKSKLKHEPLAPKKKAERAPFQPLLEKSSFQSQSYTEASSTASARNNISRGIRSSSNLSDAKSKMKWTIVLDTSSLLDKESRKPLQLLQGLKGTHLVVPRTVLRELNEVKRSRSFLFRRRTEIASSALDWIEECKVNSKWWIQVQSPTEETKAIAPTPPVTPQSNGSSAFPFSLHWNNYAPEIDSPTSEDQVLECALLYRNRNRDEKLVLLSNDVTLKIKAMAEGVICETPHEFYESLVNPFSERFMWTESTARGRTWSHLDNDVLRERYNDRACRRKSTYNRGESGAAAKGLKLILLHNSHYGHTH
InterPro domains: - IPR000253: Forkhead-associated (FHA) domain (domain) [63-132]
- IPR008984: SMAD/FHA domain superfamily (homologous_superfamily) [63-144]
- IPR002716: PIN domain (domain) [1239-1400]
- IPR029060: PIN-like domain superfamily (homologous_superfamily) [1236-1408]
Interaction partners: - Nucleolar-like protein
- Kinesin-like protein KIN-14Q
- Protein POLLENLESS 3-LIKE 2
- Sister chromatid cohesion protein PDS5 homolog E
- Dymeclin
- Protein ALTERED SEED GERMINATION 2
- Probable pectate lyase 8
- Protein JASON
- DNA topoisomerase 1 beta
- Protein SCAR2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0009628 (response to abiotic stimulus), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0009719 (response to endogenous stimulus), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0044238 (primary metabolic process), GO:0001101 (response to acid chemical), GO:0009414 (response to water deprivation), GO:0010035 (response to inorganic substance), GO:1901360 (organic cyclic compound metabolic process), GO:0009415 (response to water), GO:0006139 (nucleobase-containing compound metabolic process), GO:0009755 (hormone-mediated signaling pathway), GO:0046483 (heterocycle metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0071495 (cellular response to endogenous stimulus), GO:0060255 (regulation of macromolecule metabolic process), GO:0016043 (cellular component organization), GO:1901700 (response to oxygen-containing compound), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0009756 (carbohydrate mediated signaling), GO:0043170 (macromolecule metabolic process), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:1902074 (response to salt), GO:0097305 (response to alcohol), GO:0032870 (cellular response to hormone stimulus), GO:0090304 (nucleic acid metabolic process), GO:0071310 (cellular response to organic substance), GO:0033993 (response to lipid), GO:0006259 (DNA metabolic process), GO:0006325 (chromatin organization), GO:0009737 (response to abscisic acid), GO:1901701 (cellular response to oxygen-containing compound), GO:0010468 (regulation of gene expression), GO:0009738 (abscisic acid-activated signaling pathway), GO:0040029 (epigenetic regulation of gene expression), GO:0071215 (cellular response to abscisic acid stimulus), GO:0097306 (cellular response to alcohol), GO:0006310 (DNA recombination), GO:0071396 (cellular response to lipid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)