wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Protein CUSTOS (A9C3N6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Essential for Spemann-Mangold organizer formation and subsequent anterior head development in the embryo. Inhibits canonical Wnt signaling pathway by antagonizing nuclear import of beta-catenin (ctnnb1) during embryogenesis.
Subcellular location: Nucleus envelope {ECO:0000250|UniProtKB:P0DPK0}.
Sequence: MSESSSEDENTARLKEAVWSFKPEDVKINGKENNGRQSHRADVSKHEHDGNELGTTPEFRSHVAKKLGTYLDGCISEVCSDTVEPAQSENREDEEGFRLFSSSTPGKWMEQSPPPPPKRRPVPSSSDSDSEMEMRFREAAVSLSDILGPVAQNLSEKTEEKSTKEETEDTVTKMKKKKKRKTSSEESQDKVNHQTEKQSNVEGNQEQTTAGERLKKKKKKKKKKRKKLEKDIKKDE
InterPro domains: - IPR026694: Protein CUSTOS (family) [1-228]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0048856 (anatomical structure development), GO:0023057 (negative regulation of signaling), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0031128 (developmental induction), GO:0050794 (regulation of cellular process), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0060061 (Spemann organizer formation), GO:0010646 (regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0030111 (regulation of Wnt signaling pathway), GO:0030178 (negative regulation of Wnt signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Fiber-specific MADS protein (G0X3E3)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MGRGRVQLKRIENKINRQVTFSKRRSGLLKKAHEISVLCDAQVALMVFSSKGKLFEYATESCMERILERYERYSFTEIQCATDEIQQNGNWTWEHAKLKARMETLQRNLRINLWLNQFLSFRKRTKNCKNRITYLQRRRRRKLMWSRHIGS
InterPro domains: - IPR033896: MADS MEF2-like, N-terminal (domain) [2-74]
- IPR002100: Transcription factor, MADS-box (domain) [1-61]
- IPR050142: MADS-box/MEF2 Transcription Factor (family) [3-109]
- IPR036879: Transcription factor, MADS-box superfamily (homologous_superfamily) [2-91]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0071554 (cell wall organization or biogenesis), GO:0009791 (post-embryonic development), GO:0048316 (seed development), GO:0090376 (seed trichome differentiation), GO:0048608 (reproductive structure development), GO:0071669 (plant-type cell wall organization or biogenesis), GO:0044085 (cellular component biogenesis), GO:0009888 (tissue development), GO:0042546 (cell wall biogenesis), GO:0030154 (cell differentiation), GO:0090379 (secondary cell wall biogenesis involved in seed trichome differentiation), GO:0048731 (system development), GO:0090558 (plant epidermis development), GO:0061458 (reproductive system development), GO:0010026 (trichome differentiation), GO:0009832 (plant-type cell wall biogenesis), GO:0010154 (fruit development), GO:0009834 (plant-type secondary cell wall biogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Nucleosome assembly protein (Q8I2W3)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Not known
Sequence: MKRDRSENSVENTDPKHTKIENDDPLMPFMQDFEDIQKDIEQLDIKCAHEQMNIQKQYDEKKKPLFEKRDEIIQKIPGFWANTLRKHPALSDIVPEDIDILNHLVKLDLKDNMDNNGSYKITFIFGEKAKEFMEPLTLVKHVTFDNNQEKVVECTRIKWKEGKNPIAAVTHNRSDLDNEIPKWSIFEWFTTDELQDKPDVGELIRREIWHNPLSYYLGLEEFDEFDDDFDEEFDDDDDDDDDDDDDDDDDDKDDDLDGDDDGNNDDNDD
InterPro domains: - IPR002164: Nucleosome assembly protein (NAP) (family) [29-241]
- IPR037231: NAP-like superfamily (homologous_superfamily) [23-218]
- IPR036674: p53-like tetramerisation domain superfamily (homologous_superfamily) [29-73]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042393 (histone binding), GO:0019899 (enzyme binding), GO:0019900 (kinase binding), GO:0019901 (protein kinase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0033554 (cellular response to stress), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0006974 (cellular response to DNA damage stimulus), GO:0006259 (DNA metabolic process), GO:0006310 (DNA recombination), GO:0006281 (DNA repair), GO:0000725 (recombinational repair), GO:0016444 (somatic cell DNA recombination), GO:0006302 (double-strand break repair), GO:0000724 (double-strand break repair via homologous recombination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: FCP1 homology domain-containing protein (Q388H5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MRRSGFVAPPDNPQYGKMETRDYEEWGSPHDSSVRAHQQSPLRLARAYSVPYPGLSTTWGMGGSSGISTTSCGKVKHNVHHQKYRHSPYGTSFNIFSALPSTLVPAVAGRRSDIHPSVDKQDVAARAVGNIPPHRAYRSASVGCFEELSKPDTPTDTPSQSSPALTSCWLSPWSRFGGRDGQLDVECGTVYPSTQNSSPVSCGGAVAAFGGMTSVLTRKSSRQPTQVLHPSPKKELDQLIPDGLTPSSNESDTNSAPSSQSRHTKNQTTFSGSAKNHDRPSGHGGLSDCWSTIQPPNITDSGEGEIYVPETTQPVASSVAPPDRPVGQLLRDLLSYLEVDRGFTTSRCVGAEEPHCNHRRQEHMEDCAPQRCASASPELHVPDVQAAPHHSGYFSPVRQGSVDRGKVTQYLLPEQRSEHVGRTTCCLDLDDTLVHTFERRPSWWNPAENSFHLEIELNIPTSADQVGTYAAASAGCGSEGYEPDKACASTPSQPSSPQLVNRKAQLSPMCSARSRLQQRLYVCIRPFAKELLEYCFETFEVVFFTTGTEEYATSIFDHLDPHHKAHRLYRHHCTAVGDTYKKDLSLLGRPLDRVILLDDRGPEVSFQPNNVLFCDPFIIEEMDDALQRTQGDDVLSSFLKLLRTLATLPPYLMLQAMRDYQDAVARVWEEDVPSPPE
InterPro domains: - IPR004274: FCP1 homology domain (domain) [418-642]
- IPR023214: HAD superfamily (homologous_superfamily) [398-649]
- IPR050365: Mitochondrial import inner membrane translocase subunit TIM50 (family) [306-646]
- IPR036412: HAD-like superfamily (homologous_superfamily) [409-629]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0004721 (phosphoprotein phosphatase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0016791 (phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0006793 (phosphorus metabolic process), GO:0036211 (protein modification process), GO:0006796 (phosphate-containing compound metabolic process), GO:0043412 (macromolecule modification), GO:0016311 (dephosphorylation), GO:0006470 (protein dephosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031967 (organelle envelope), GO:0005783 (endoplasmic reticulum), GO:0005635 (nuclear envelope), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Proline-rich protein 32 (B1ATL7)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MACIENVLGGHAPSPLVVSVDKNGNQELHHDMPLQCLSSKPEDDAEPWGQPQVPLRPSVNVLTDLDSKQLEWPSERTGSCIPLHSLRAHRHPYGPPPAVAEESLATAEVNSSDALAGWRQEGQDAINVSWEVSGGPPALIVGGTKVNNGGTERGSNNARLHVALPQGKGFFPPRGPQVRGPSHIPTLRSGIVMEVPPGNTRIACRGKLAHVSFPLRGPCHPMHNWPRPIPLSSSTPGLPSCSTVHCFIPPRPPIFNPFLTMPLPFAPPPIFGPPLPSYFAHFHSGGMPAPASPNREHS
InterPro domains: - IPR027891: Protein of unknown function DUF4645 (family) [1-298]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0010468 (regulation of gene expression), GO:0043484 (regulation of RNA splicing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Tyrosyl-DNA phosphodiesterase 1 (E7EPD8)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MSQEGDYGRWTISSSDESEEEKPKPDKPSTSSLLCARQGAANEPRYTCSEAQKAAHKRKISPVKFSNTDSVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQKQAEKVVIKKEKDISAPNDGTAQRTENHGAPACHRLKEEEDEYETSGEGQDIWDMLDKGNPFQFYLTRVSGVKPKYNSGALHIKDILSPLFGTLVSSAQFNYCFDVDWLVKQYPPEFRKKPILLVHGDKREAKAHLHAQAKPYENISLCQAKLDIAFGTHHTKMMLLLYEEGLRVVIHTSNLIHADWHQKTQGIWLSPLYPRIADGTHKSGESPTHFKADLISYLMAYNAPSLKEWIDVIHKHDLSETNVYLIGSTPGRFQGSQKDNWGHFRLKKLLKDHASSMPNAESWPVVGQFSSVGSLGADESKWLCSEFKESMLTLGKESKTPGKSSVPLYLIYPSVENVRTSLEGYPAGGSLPYSIQTAEKQNWLHSYFHKWSAETSGRSNAMPHIKTYMRPSPDFSKIAWFLVTSANLSKAAWGALEKNGTQLMIRSYELGVLFLPSAFAPAKRIKDEVEASFSGSRQFQSETEVLRWQPGANGHLSCAI
InterPro domains: - IPR010347: Tyrosyl-DNA phosphodiesterase I (family) [31-559]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:1901363 (heterocyclic compound binding), GO:0016787 (hydrolase activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0097159 (organic cyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0140097 (catalytic activity, acting on DNA), GO:0003677 (DNA binding), GO:0042578 (phosphoric ester hydrolase activity), GO:0003690 (double-stranded DNA binding), GO:0008081 (phosphoric diester hydrolase activity), GO:0003697 (single-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0033554 (cellular response to stress), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0006974 (cellular response to DNA damage stimulus), GO:0006259 (DNA metabolic process), GO:0006281 (DNA repair), GO:0006302 (double-strand break repair)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Mon2/Sec7/BIG1-like HUS domain-containing protein (Q583Q8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MPAPLATFTKTKWLTFFAELTAKITHHNLLVVLEGCELVKRLLVSRVSVAAFLEEGNFLLLLVDSLVGNMLNNEPFEVNVPIGTNEKLIFTQLETLSLFVDMMVALHADSDPYYCLLVQARAGVLLGTLVSLLRRQQSNFFGIIAIMVKALLDIPLGRAVTQSQTCGAPSVALACHLQQLQTSIEGHMEILQESSEILKGLSTTPNLVMRHCAQLLFNLVSKQLKRIRRIEGGKVFAEGNTGTDGDSRLGCGAHVRDETVVESPFTGHCAQTTANYGSAFDPSGSAPSPGISADGTKLSISREDTEETIVTEEADVCVPSEEYTECFEQLARSRSHGEYLCGMNSLWCLTVVGGTELQRHFTTACFEKAFRRFLQTMPANNQDHIVFSSILLWLSHMMSNHHICDETRECIFSLACPALIELVLEDIRSDEPPGEREDNSTVTNSFPHTSTDNIDVSSFLSAGSFMRYSSIHSAPSTVRASCTKLAERPSASFLILSFLLITERSCGQRVLERWVRHVGLFAMIEKLIRRVAHVKSVLVDTPTTTDGVLSDEVYLSCAMNTSRTEHVALGALACKLLSSIAWNHGPVIGKQLASETSRMLQTIIPLLLQIAVHNPTLTSAVENVSGSALHYLPTSQRSARYTSLGECSLVALDACFWVMETAQLSAVSLESVIPNLQALSRATGNSIHPALRAAPYRAVARLCQSTDDVLLVASEMPSLLKAAVNSVLEYSVKVPQWEAAAAAEGLIHIVNKTSSDINVEKKFSFSRSALPVKLLELAALNGITYATGTFLSLMVVLFAQQKRLAEHADEEPLSCVLLPCGRASLEYWSKLINIATWSGERLLVAHKKVIPASPVTKDAQSRALGSIEGIAVQFYFVSALSRALQFLLGAYPEYRSHFSEDVVWLFFTSTFALPSPREVFQMLFVRFGVKVSHHNSIERAYECMLQWTIELFLFWVGDVGIGVGTNSKRKSQKLASLPSKLFDSLCGIMQNAKVSQQTRANVCGLVSAIIIRTGSGDAASTTGSSSACASLAILRETLYKTLDAFSAKLFSASINLGTSSCVSGMQCRLVSLFAGANERARQCGWFEERLAELNKRMRELKEKHGVLSAHELDSLLVLFSSVFSVIAYPKCPALSQKLQQQLCLSLHGAVGYGTTRRAAFQTALALTRSEEGRRFLLQEVTACGDPLVRTCFGRLLMVTLDLADDIEPSYRRKHYGSKNKAQNATIIEREANRTLVKTLGFEVCATACAEGCEAFTNGVLKSKGVERVEGLFLKCEQERIEVPLSVHRLIAAISFHADAQLAIIRRKELMTLLVEWAGELSVAGTLALLTLRNLCFNPSLKAQLCQNDRILQLFKQFVCMPVAPQPLQALQPDNNSSEFDAHHTDIASRSQQNSGTGGTRLERHKKGGIVSTTTATASCQADNLSILRCKELAVTGYWALMYDNQRGKSHVRNVLSQAPAVKINSVVAALDQLCVEPSERACVEHVMEAVGNMKALGRSVS
InterPro domains: - IPR030791: Rotatin (family) [1289-1457]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0042995 (cell projection), GO:0020016 (ciliary pocket), GO:0043227 (membrane-bounded organelle), GO:0120025 (plasma membrane bounded cell projection), GO:0005929 (cilium)
Protein: Dahlein-5.4 (P84270)
Organism: Ranoidea dahlii (Dahl's aquatic frog) (Litoria dahlii)
Function: Has no antimicrobial activity. Strongly inhibits the formation of NO by neuronal nitric oxide synthase at micromolar concentrations.
Subcellular location: Secreted {ECO:0000269|PubMed:11555873}.
Sequence: GLLGSIGKVLGGYLAEKLKPK
InterPro domains: - IPR032021: Frog antimicrobial peptide, caerin-type, Litoria (family) [1-21]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0065009 (regulation of molecular function), GO:0050790 (regulation of catalytic activity), GO:0044092 (negative regulation of molecular function), GO:0051341 (regulation of oxidoreductase activity), GO:0043086 (negative regulation of catalytic activity), GO:0051354 (negative regulation of oxidoreductase activity), GO:0032768 (regulation of monooxygenase activity), GO:0050999 (regulation of nitric-oxide synthase activity)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: IP18173p (Secretory 20, isoform A) (Secretory 20, isoform B) (Q9VNI9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004163}; Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004163}.
Sequence: MDKDAFTLQAIRQDLIDNNLQAKAIIHDILNSRTSIAELEELNEAGRSKLSAIRKSIERLDDWARDTADSALANEVDDHRDQFSKTLQAFRKANVSTMLEIEKANREELMAITGESELRQRTTTRARHNQGSLVSQENDVTEKMLAISRHLSETTQKSAITLETLVASSQNVEATSDELHHTAGSISMSGKLLKKYGRRECTDKMLLFFAFSLFLACVFYIVQKRLF
InterPro domains: - IPR056173: Sec20, C-terminal (domain) [135-226]
- IPR005606: Sec20 (family) [7-226]
Interaction partners: - Secretory 22, isoform B
- Vesicle transport protein USE1
- Syntaxin-18
- Syntaxin-5
- LD03592p
- Synaptosomal-associated protein
- LD27967p
- BET1 homolog
- Probable Golgi SNAP receptor complex member 2
- Vesicle-associated membrane protein 7
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0060090 (molecular adaptor activity), GO:0030674 (protein-macromolecule adaptor activity), GO:0005515 (protein binding), GO:0005484 (SNAP receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0071840 (cellular component organization or biogenesis), GO:0140352 (export from cell), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0032940 (secretion by cell), GO:0016043 (cellular component organization), GO:0045184 (establishment of protein localization), GO:0006810 (transport), GO:0035592 (establishment of protein localization to extracellular region), GO:0071702 (organic substance transport), GO:0046903 (secretion), GO:0008104 (protein localization), GO:0071705 (nitrogen compound transport), GO:0009306 (protein secretion), GO:0006996 (organelle organization), GO:0010256 (endomembrane system organization), GO:0015031 (protein transport), GO:0007030 (Golgi organization), GO:0071692 (protein localization to extracellular region)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0098796 (membrane protein complex), GO:0012505 (endomembrane system), GO:0031201 (SNARE complex), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)
Protein: peptidylprolyl isomerase (EC 5.2.1.8) (Q7ZZA3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Sequence: MATRTGIVLIFLAVFAFVAAEDGESKESVIEQLVVETLVMPESCTITSEMGDTLQIHYTGRLMDGKVIDTSLSREPLVVELGKRSVITGLEQALVGVCEGQKIKAMIPAHLAYGKRGYPPTIPGDSTLEFEVEVISLSQQTPWQKLINDILPLLCLALVPTLLGLVGLYLYNKAHAQPQGKKKSKDKKSKKK
InterPro domains: - IPR001179: FKBP-type peptidyl-prolyl cis-trans isomerase domain (domain) [45-138]
- IPR046357: Peptidyl-prolyl cis-trans isomerase domain superfamily (homologous_superfamily) [23-139]
- IPR044609: Peptidyl-prolyl cis-trans isomerase FKBP2/11 (family) [12-140]
Interaction partners: - Tetraspanin
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016853 (isomerase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0003755 (peptidyl-prolyl cis-trans isomerase activity), GO:0016859 (cis-trans isomerase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0072001 (renal system development), GO:0001822 (kidney development), GO:0048793 (pronephros development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)