Protein: steroid 11beta-monooxygenase (EC 1.14.15.4) (Cytochrome P450C11) (A1XRK1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Mitochondrion membrane {ECO:0000256|ARBA:ARBA00004325}.
Sequence: MFSSCAGSVCARPHLCVRASVCVRPLHQSSRSAGAARLFQEIPDTGSNGWMNLLRFWRDGRFSRMHKHMEESFRRLGPIYREHLGSQSSVNIMLPMDTGELFRSEGLHPRRMTLQPWATHRETRRHSKGVFLKNGTEWRADRLLLNREVMVSSSVHRFLPLLDEVAQDFCRSLRRRVQADGFEKAGQHTLTLDPSPDLFRFALEASCHVLYGERIGLFSSCPSDESERFISAVERMLATTPPLLYLPPRLLLRLRASLWTTHATAWDDIFSHAEQRIQRSYQRLQARPSAAPDCSFPGVLGKLMEAGQLSLELIRANITELMAGGVDTTAVPLQFALFELARNPDVQECVRAQVLSSWQQASGDPLKALQGAPLLKGTIKETLRLYPVGITVQRYPVRDIVLQNYHVPAGTLVQVCLYPLGRSAEVFSRPECFDPSRWSADADAGSAGGFRSLAFGFGSRQCVGRRIAENEMQLLLMHILRTFKLTVSSTEELSTKYTLILQPECPPRITFSTLTHQH
InterPro domains: - IPR036396: Cytochrome P450 superfamily (homologous_superfamily) [34-517]
- IPR017972: Cytochrome P450, conserved site (conserved_site) [455-464]
- IPR001128: Cytochrome P450 (family) [46-509]
- IPR002401: Cytochrome P450, E-class, group I (family) [73-485]
- IPR050479: Cytochrome P450, families 11 and 27 (family) [5-514]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0004497 (monooxygenase activity), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen), GO:0016713 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen), GO:0008395 (steroid hydroxylase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0042592 (homeostatic process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048878 (chemical homeostasis), GO:0065008 (regulation of biological quality), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009058 (biosynthetic process), GO:0009653 (anatomical structure morphogenesis), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0042445 (hormone metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:0003008 (system process), GO:0035295 (tube development), GO:0050801 (monoatomic ion homeostasis), GO:1901615 (organic hydroxy compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0048729 (tissue morphogenesis), GO:1901576 (organic substance biosynthetic process), GO:0048598 (embryonic morphogenesis), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0009888 (tissue development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0072028 (nephron morphogenesis), GO:0003014 (renal system process), GO:0008217 (regulation of blood pressure), GO:0044249 (cellular biosynthetic process), GO:0098771 (inorganic ion homeostasis), GO:0072006 (nephron development), GO:0010817 (regulation of hormone levels), GO:0003013 (circulatory system process), GO:0042446 (hormone biosynthetic process), GO:0072001 (renal system development), GO:0016125 (sterol metabolic process), GO:1902652 (secondary alcohol metabolic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0060562 (epithelial tube morphogenesis), GO:0072009 (nephron epithelium development), GO:0061326 (renal tubule development), GO:0055080 (monoatomic cation homeostasis), GO:0008015 (blood circulation), GO:0003073 (regulation of systemic arterial blood pressure), GO:0008202 (steroid metabolic process), GO:0042359 (vitamin D metabolic process), GO:1901617 (organic hydroxy compound biosynthetic process), GO:0001977 (renal system process involved in regulation of blood volume), GO:1901617 (organic hydroxy compound biosynthetic process), GO:0001977 (renal system process involved in regulation of blood volume), GO:0039019 (pronephric nephron development), GO:0002009 (morphogenesis of an epithelium), GO:0060429 (epithelium development), GO:0001822 (kidney development), GO:0060993 (kidney morphogenesis), GO:0008610 (lipid biosynthetic process), GO:0072080 (nephron tubule development), GO:0046165 (alcohol biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0072080 (nephron tubule development), GO:0048793 (pronephros development), GO:0006694 (steroid biosynthetic process), GO:0016126 (sterol biosynthetic process), GO:0072112 (podocyte differentiation), GO:0072073 (kidney epithelium development), GO:0039022 (pronephric duct development), GO:0008203 (cholesterol metabolic process), GO:0030003 (intracellular monoatomic cation homeostasis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)