Protein: Immunoglobulin superfamily member 23 (A1L1A6)
Organism: Homo sapiens (Human)
Function: May be involved in osteoclast differentiation
Subcellular location: Cell membrane; Single-pass membrane protein
Sequence: MRAKPQSPLPRNPVPAWSPPTTTTDPMLEKDAAGGDFPANLVLQLMPLKTFPAAIRGVIQSELNYSVILQWVVTMDPEPVLSWTFSGVPCGMGEKLFIRRLSCEQLGTYMCIATNSKKQLVSEPVTISLPKPIMQPTEAEPMEPDPTLSLSGGSAIGLLAAGILGAGALIAGMCFIIIQSLRTDRQRIGICS
InterPro domains: - IPR013783: Immunoglobulin-like fold (homologous_superfamily) [59-129]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [63-119]
- IPR007110: Immunoglobulin-like domain (domain) [20-128]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0001775 (cell activation), GO:0045321 (leukocyte activation), GO:0007155 (cell adhesion), GO:0002684 (positive regulation of immune system process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051716 (cellular response to stimulus), GO:0002682 (regulation of immune system process), GO:0002253 (activation of immune response), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0048522 (positive regulation of cellular process), GO:0002764 (immune response-regulating signaling pathway), GO:0031341 (regulation of cell killing), GO:0002831 (regulation of response to biotic stimulus), GO:0032103 (positive regulation of response to external stimulus), GO:0050776 (regulation of immune response), GO:0002757 (immune response-activating signaling pathway), GO:0098609 (cell-cell adhesion), GO:0002366 (leukocyte activation involved in immune response), GO:0002833 (positive regulation of response to biotic stimulus), GO:0080134 (regulation of response to stress), GO:0031343 (positive regulation of cell killing), GO:0050778 (positive regulation of immune response), GO:0032101 (regulation of response to external stimulus), GO:0007166 (cell surface receptor signaling pathway), GO:0031349 (positive regulation of defense response), GO:0002699 (positive regulation of immune effector process), GO:0046649 (lymphocyte activation), GO:0031347 (regulation of defense response), GO:0002429 (immune response-activating cell surface receptor signaling pathway), GO:0045089 (positive regulation of innate immune response), GO:0002768 (immune response-regulating cell surface receptor signaling pathway), GO:0045088 (regulation of innate immune response), GO:0002703 (regulation of leukocyte mediated immunity), GO:0001910 (regulation of leukocyte mediated cytotoxicity), GO:0030101 (natural killer cell activation), GO:0002705 (positive regulation of leukocyte mediated immunity), GO:0001912 (positive regulation of leukocyte mediated cytotoxicity), GO:0002706 (regulation of lymphocyte mediated immunity), GO:0042269 (regulation of natural killer cell mediated cytotoxicity), GO:0002708 (positive regulation of lymphocyte mediated immunity), GO:0045954 (positive regulation of natural killer cell mediated cytotoxicity), GO:0002717 (positive regulation of natural killer cell mediated immunity), GO:0002715 (regulation of natural killer cell mediated immunity)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0030141 (secretory granule), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0101002 (ficolin-1-rich granule), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0012506 (vesicle membrane), GO:0030667 (secretory granule membrane), GO:0070820 (tertiary granule), GO:0031982 (vesicle), GO:0030659 (cytoplasmic vesicle membrane), GO:0097708 (intracellular vesicle), GO:0101003 (ficolin-1-rich granule membrane)