Protein: Hepatocyte nuclear factor 4-alpha (Q8AXB6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU004334}.
Sequence: MEMADYSEALDPAYTTLEFENMQVLAMSTDSSPQESANMNAANHLGAGTLCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFNRQCIVDKDKRNQCRYCRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINALIQADVLSRQISSPGPILNGDIRTKKVAAIMDVCESMKQQLLVLVEWAKYIPAFCDLPLDDQVALLRAHAGEHLLLGAAKRSMMYKDILLLGNDHIIPRNCPELEVSRVAVRILDELVLPFQDLQIDDNEYACLKAIVFFDPDAKGLSDPSKIKRMRYQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMAKIDNLLQEMLLGGSANEAPHAHHSLHPHLVQEHLSNNVIVTANMATPLHNGQMSTPETPIPSPPTASGSDHYKMASGVIATVPKQPSSIPQPTITKQEAI
InterPro domains: - IPR049635: Hepatocyte nuclear factor 4, ligand-binding domain (domain) [142-363]
- IPR035500: Nuclear hormone receptor-like domain superfamily (homologous_superfamily) [117-367]
- IPR049636: Hepatocyte nuclear factor 4-like, DNA-binding domain (domain) [51-126]
- IPR050274: Nuclear hormone receptor family NR2 subfamily (family) [38-365]
- IPR000536: Nuclear hormone receptor, ligand-binding domain (domain) [138-367]
- IPR001628: Zinc finger, nuclear hormone receptor-type (domain) [48-123]
- IPR001723: Nuclear hormone receptor (family) [112-343]
- IPR013088: Zinc finger, NHR/GATA-type (homologous_superfamily) [42-131]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:0043207 (response to external biotic stimulus), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0009617 (response to bacterium), GO:0048513 (animal organ development), GO:0031018 (endocrine pancreas development), GO:0031099 (regeneration), GO:0031100 (animal organ regeneration), GO:0035270 (endocrine system development), GO:0003309 (type B pancreatic cell differentiation), GO:0002064 (epithelial cell development), GO:0060429 (epithelium development), GO:0031016 (pancreas development), GO:0030855 (epithelial cell differentiation), GO:1990798 (pancreas regeneration), GO:0002066 (columnar/cuboidal epithelial cell development), GO:0003323 (type B pancreatic cell development), GO:0002065 (columnar/cuboidal epithelial cell differentiation), GO:0002068 (glandular epithelial cell development), GO:0002067 (glandular epithelial cell differentiation), GO:0035883 (enteroendocrine cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)