Protein: PHD-type domain-containing protein (Q18605)
Organism: Caenorhabditis elegans
Function: Not known
Sequence: MQKKEKEGRRKLKYDSNDGLLPEIRRVCGFPHHISEELSARGSGKKKKQVEEEWKWPEAQICGICSSGGNILCCEQCPASFHLACIGYESSDLPDDNFYCNRCRNLPENVRLFPPEKCSPSVNPVLRVENENHRNWEAIEYHCNRLRDEEQAEKMKKDVAYGPKSEFAEIQDCFRDKNLLKALGMANPMDYTIPPEFQADRDCFSGDAMEDKRPTIMGEVCAECNLKDDWTRMLKCDFCDLIWHQKCVTPPLIHVRAYFYWMCPRHPETVIDSVLIGDEISREDRRRLYDKYADVEPSYEIFEEFCIKTEQFRMKSEVFDSEEMYYDPEEASTSFMQTVIKPRQTSRKTTGRSASKKKSNGRFFASSWDFPGLSSRETSPSRKNSRKSPDSVATERKDRVLDKIDKKRSIKLTEEEIIMSIMPVEESSRAEYLTQKMLGTDIEQSTNFFNRHSAMIDRIRAFYGNLPEKELIKLMREDLDPVETIRGGGTQSIISQNEKPYRKKLKADVEVLIQHVGLGTDSTERHFNSIGTEAFYRRCAPPVTARNVLNQKTLREVVLNSQKEAHEGAGVYEYHAEPEQLENLVLLAYEPSFESPEDRDTYFVPSMTIWSKEPICALTRKWAASGASKQAPPSSSSSEAPSVEAEVKEEVVEEEDEENEARMRRESTATSSIVYNNDTGPLEFIEENMPPPAATITEKSDPFDFSSLEMPEIHEKAETVYEAEGYYGESDDLPLDLRRTKSESDLVDRIIWPLVRSALQNFIRREDCHQMHLEHNYSSLYQTHDSDEENQPVVEVEKLITYEEYQENLYSAEFASPQTPPPIPPPPAVYYDNFSDAPRKRGRPVGSRNRKEGDTTIPKQQRKRNPQPVGRGRGRGGGRPRGSRSSRGSMDDGGGSRRHSTASDANESAELLNQPVTKQLRDEIKEIKLKYTKMMMDRGFEQAKDEYFRNRDAALSKWTPEQWKEHNEQCVAARLSSLIPYDQRYFLPTQRVLARLDLEDGDLRLPAVHLPIAIQRCVTKLGTAHDCHVRCDKLTGDAWCSVLADYHCDIVRDYYSDNFYISTLGTEAVFVDGRAVRRPRLTPFEAAEKLRTRGSSTIIPPHIKCRCQKHSDLQISRQESTGELVRCGILKLEHGARIQIGCVAFIFSRI
InterPro domains: - IPR000253: Forkhead-associated (FHA) domain (domain) [1018-1076]
- IPR011011: Zinc finger, FYVE/PHD-type (homologous_superfamily) [51-266]
- IPR019787: Zinc finger, PHD-finger (domain) [59-106]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [38-268]
- IPR019786: Zinc finger, PHD-type, conserved site (conserved_site) [62-103]
- IPR042163: PHD finger protein 12 (family) [46-1066]
- IPR001965: Zinc finger, PHD-type (domain) [61-267]
Interaction partners: - Paired amphipathic helix protein sin-3
- Chromo domain-containing protein
- Mortality factor related protein 1
- C2H2-type domain-containing protein
- Bromo domain-containing protein
- Probable histone-binding protein rba-1
- Probable histone-binding protein lin-53
- DEK_C domain-containing protein
- Histone deacetylase
- Putative histone deacetylase 2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042393 (histone binding), GO:0140030 (modification-dependent protein binding), GO:0035064 (methylated histone binding), GO:0140034 (methylation-dependent protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0002376 (immune system process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0006955 (immune response), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0045087 (innate immune response), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:1902494 (catalytic complex), GO:0140513 (nuclear protein-containing complex), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:1990234 (transferase complex), GO:0035097 (histone methyltransferase complex), GO:0043229 (intracellular organelle), GO:0034708 (methyltransferase complex), GO:0043227 (membrane-bounded organelle), GO:0044666 (MLL3/4 complex), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)