wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Metaxin glutathione S-transferase domain-containing protein (Q38CI9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MPLMSADGSGELPPVMLHRYPVTLGLPTADPYALAIECMLRIVGAHYKKRDGGLPVTLEVPVDGRNKPAMKRHEGLTSCLQLIESATHQDAEVITSALEPEALCVRLTAEVVLIPAFVYITHSDAGILRNAIQKAVEPKVASMWQRFRGSYSRHVVQQTSFCRSYKNMGEAIENVERCLRAIEAICSINTAGNGMFILGTERPCSADALIYAAASSFFHADFASRQASGDIIAMQQRLREGCPTLLTYVERLRGLYFEDYSAFYHLRAPTCGMEGEATQKAAEETFVRGRWKVLAFTGVFSITYFLVANIDVFSAVLLHYLEDDGEEEFLEDEE
InterPro domains: - IPR050931: Mitochondrial Protein Transport Metaxin (family) [14-273]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0071840 (cellular component organization or biogenesis), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0016043 (cellular component organization), GO:0046907 (intracellular transport), GO:0045184 (establishment of protein localization), GO:0006810 (transport), GO:0006839 (mitochondrial transport), GO:0071702 (organic substance transport), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0008104 (protein localization), GO:0006996 (organelle organization), GO:0015031 (protein transport), GO:0072594 (establishment of protein localization to organelle), GO:0072655 (establishment of protein localization to mitochondrion), GO:0007005 (mitochondrion organization), GO:0033365 (protein localization to organelle), GO:0006605 (protein targeting), GO:0006626 (protein targeting to mitochondrion), GO:0070585 (protein localization to mitochondrion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0019867 (outer membrane), GO:0043227 (membrane-bounded organelle), GO:0005740 (mitochondrial envelope), GO:0031968 (organelle outer membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0031966 (mitochondrial membrane), GO:0005741 (mitochondrial outer membrane)
Protein: Ovoinhibitor (OI) (OvoI) (Serine protease inhibitor Kazal-type 5) (allergen Gal d OIH) (P10184)
Organism: Gallus gallus (Chicken)
Function: Serine protease inhibitor involved in antimicrobial egg defense preventing contamination of table eggs (non-fertilized eggs) and protecting the chick embryo (fertilized eggs) (Probable). Inhibits trypsin, chymotrypsin, elastase, subtilisin and a proteinase of fungus Aspergillus oryzae. Inhibits calcium-activated potassium channels KCNMA1 (bovine) and slo (Drosophila). Has antibacterial activity against B.thuringiensis LMSA 3.06.004, but not against S.aureus CIP 103 811, P.aeruginosa PAO1, B.cereus ATCC6464 or B.subtilis ATCC 6633.
Subcellular location: Secreted {ECO:0000269|PubMed:22010862}.
Sequence: MTDWVLHHKVGPLDMTTRYIFPLLPLPFLPHSESKRAVCAPRCSAMRTARQFVQVALALCCFADIAFGIEVNCSLYASGIGKDGTSWVACPRNLKPVCGTDGSTYSNECGICLYNREHGANVEKEYDGECRPKHVTIDCSPYLQVVRDGNTMVACPRILKPVCGSDSFTYDNECGICAYNAEHHTNISKLHDGECKLEIGSVDCSKYPSTVSKDGRTLVACPRILSPVCGTDGFTYDNECGICAHNAEQRTHVSKKHDGKCRQEIPEIDCDQYPTRKTTGGKLLVRCPRILLPVCGTDGFTYDNECGICAHNAQHGTEVKKSHDGRCKERSTPLDCTQYLSNTQNGEAITACPFILQEVCGTDGVTYSNDCSLCAHNIELGTSVAKKHDGRCREEVPELDCSKYKTSTLKDGRQVVACTMIYDPVCATNGVTYASECTLCAHNLEQRTNLGKRKNGRCEEDITKEHCREFQKVSPICTMEYVPHCGSDGVTYSNRCFFCNAYVQSNRTLNLVSMAAC
InterPro domains: - IPR002350: Kazal domain (domain) [67-517]
- IPR036058: Kazal domain superfamily (homologous_superfamily) [65-508]
Interaction partners: - Ovotransferrin
- Ovotransferrin
- Ovotransferrin
- chymotrypsin
- Ovostatin
- Uncharacterized protein.
- Gallinacin-9
- Ovalbumin
- Gallinacin-10
- Cystatin
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140678 (molecular function inhibitor activity), GO:0061134 (peptidase regulator activity), GO:0004857 (enzyme inhibitor activity), GO:0061135 (endopeptidase regulator activity), GO:0030414 (peptidase inhibitor activity), GO:0004866 (endopeptidase inhibitor activity), GO:0004867 (serine-type endopeptidase inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009719 (response to endogenous stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0048545 (response to steroid hormone), GO:0033993 (response to lipid), GO:0014070 (response to organic cyclic compound)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0045177 (apical part of cell), GO:0005615 (extracellular space), GO:0005737 (cytoplasm), GO:0005576 (extracellular region), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)
Protein: Ribonuclease G (Q726Q1)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Sequence: MTTAKKGKRKMYISVLPGEQVEVALSEDGAVTEYYVEMLHQAKTKGNIYKGVINNIDTNLQAAFVNYGAEKNGFLQIDEVHPEYYISPHDPTKGKKYPLMQKVLKAGQEVLVQVVKEPTGNKGAFLTSYLSLPGRFLVLTPGREQIGVSRKVEDDEERSRLREMLEGLSAGPGLGVIVRTVSAGTSKTTLQRDLQFLKRLWKDVRKKGTTEQTPCQIYQEPDLATRSVRDYLTDDVSEVWVDDAATAELIREFVTLVFPRKASLVKLHTDPERTLWERFGIRKQLDQIYSREVILPSGGRLVFDQTEALMAIDINSGKIAGKTNFESMALKTNTEAAESIAQQLRLRDIGGQVVIDFIEMRDHNHWREVEKTLRNAMKGDRARHDVGKMSRFGLLQVVRQRTGSSALSITMEACPCCRGSGLRRNMEWQSLQALRELHRQLRALPQGQCVHVFETSPELAFYLLNHKRERLLELERRFNLRLEVRPTGK
InterPro domains: - IPR048583: RNase E/G, thioredoxin-like domain (domain) [414-486]
- IPR019307: RNA-binding protein AU-1/Ribonuclease E/G (domain) [131-402]
- IPR003029: S1 domain (domain) [44-129]
- IPR004659: Ribonuclease E/G (family) [10-485]
- IPR012340: Nucleic acid-binding, OB-fold (homologous_superfamily) [38-135]
Interaction partners: - Polyribonucleotide nucleotidyltransferase
- Enolase
- RNA-binding protein KhpB
- ATP-dependent RNA helicase RhlE
- RNA-binding protein KhpA
- Epoxyqueuosine reductase QueH
- Nucleotide-binding protein DVU_1631
- ATP-dependent RNA helicase, DEAD/DEAH box family
- DEAD-box ATP-dependent RNA helicase RhpA
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0016043 (cellular component organization), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0043933 (protein-containing complex organization), GO:0010467 (gene expression), GO:0022607 (cellular component assembly), GO:0016070 (RNA metabolic process), GO:0065003 (protein-containing complex assembly), GO:0006396 (RNA processing), GO:0090501 (RNA phosphodiester bond hydrolysis), GO:0034470 (ncRNA processing), GO:0006364 (rRNA processing), GO:0034660 (ncRNA metabolic process), GO:0016072 (rRNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0140535 (intracellular protein-containing complex), GO:1905348 (endonuclease complex)
Protein: Elongation of very long chain fatty acids protein (EC 2.3.1.199) (Very-long-chain 3-oxoacyl-CoA synthase) (Q5JZZ4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MASLGISFHPFPDQPDERTRNWPLVDSFWTVPVLLSIYLLMVRYAPKWTTRHKPLQLRAPLFCHSLAMVFLNGYICLELYAATRDLDYNFGCQPCRVSFDPHEMRLTKAFWWFYISKILEFADTAFFILRQKWSQLSFLHVYHHSTMFVFCWILIKWMPTGSTYVPAMINSFVHIIMYGYYALSVLGPRVQRFLWWKRYLTGLQLVQFTIIFFWASQMLVRGCEYGTWITLSMAIYSLPFLFMFGKFYMQKYTVSAVGKKPI
InterPro domains: - IPR002076: ELO family (family) [14-255]
- IPR030457: ELO family, conserved site (conserved_site) [136-144]
Interaction partners: - Very long chain fatty acid elongase F
- Elongation of very long chain fatty acids protein
- very-long-chain enoyl-CoA reductase
- Elongation of very long chain fatty acids protein
- Very-long-chain
- Very-long-chain
- RH59310p)
- Elongation of very long chain fatty acids protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0004312 (fatty acid synthase activity), GO:0009922 (fatty acid elongase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0006082 (organic acid metabolic process), GO:0006631 (fatty acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0016053 (organic acid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0006633 (fatty acid biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process), GO:0072330 (monocarboxylic acid biosynthetic process), GO:0030497 (fatty acid elongation), GO:0032787 (monocarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: mitogen-activated protein kinase kinase (EC 2.7.12.2) (B1NA67)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Sequence: MLLLVLSNLSNMESEGIVIRIKTPVGDMDSPVDSPSHLNFNDLLAAIRDAMPEATVTAFEYEDEVGDRITVRSDDELKAMLSYYCNTVMEQRFNGLLPEPLQIFPRAGKTPGIRNIHGLKVNTRPESSSGRSSSAADSRSSDSLKKSSAELKKILTNGQINEHDLQYQEQLGHGNGGTVYKAYHLLGKRIVAVKVIPLDITVELQKQIMSELEILYKCDSPYIIKFYSAFFVENRISICTEFMDGGSLDVYWRIPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSVGISFMELALGSFPYPQIQKNQGSLMPLQLLQCIVDEDPPVLPVGQFSEKFVHFITQCMRKLPKERPAPNNLMDHPFIVQYNDGNTEVVSMWVCRSLEDRKAQQPQRLM
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [150-436]
- IPR053793: PB1-like domain (domain) [18-108]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [278-290]
- IPR017441: Protein kinase, ATP binding site (binding_site) [171-194]
- IPR000719: Protein kinase domain (domain) [165-418]
- IPR034851: Dual specificity mitogen-activated protein kinase kinase 5, PB1 domain (domain) [17-106]
- IPR000270: PB1 domain (domain) [30-86]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004712 (protein serine/threonine/tyrosine kinase activity), GO:0016301 (kinase activity), GO:0004708 (MAP kinase kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit) (O88456)
Organism: Mus musculus (Mouse)
Function: Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Essential for embryonic development.
Subcellular location: Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Translocates to the plasma membrane upon calcium binding. {ECO:0000250}.
Sequence: MFLVNSFLKGGGGGGGGGGLGGGLGNVLGGLISGAAGGGGGGGGGMGLGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRSHYSNIEANESEEVRQFRKLFVQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQAIYKRFDTDRSGTIGSHELPGAFEAAGFHLNEHLYSMIIRRYADESGNMDFDNFISCLVRLDAMFRAFKSLDKNGTGQIQVNIQEWLQLTMYS
InterPro domains: - IPR011992: EF-hand domain pair (homologous_superfamily) [50-266]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [182-194]
- IPR002048: EF-hand domain (domain) [112-204]
Interaction partners: - Calpain-2 catalytic subunit
- Calpain-1 catalytic subunit
- Calpastatin
- Calpain-6
- Calpain-5
- Calpain-10
- Calpain-8
- Calpain-7
- Caspase-3
- Calpain-15
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0008233 (peptidase activity), GO:0008234 (cysteine-type peptidase activity), GO:0004175 (endopeptidase activity), GO:0004197 (cysteine-type endopeptidase activity), GO:0004198 (calcium-dependent cysteine-type endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0008284 (positive regulation of cell population proliferation), GO:0042127 (regulation of cell population proliferation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Pleckstrin homology domain containing A7 (H0YDE2)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: XDALFMDLPTGPRGQQAQPQRAEKNGMLPASYGPGEQNGTGGYQRAFPPRTNPEKHSQRKSNLAQVEHWARAQKGDSRSLPLDQTLPRQGPGQSLSFPENYQTLPKSTRHPSGGSSPPPRNLPSDYKYAQDRASHLKMSSEERRAHRDGTVWQLYEWQQRQQFRHGSPTAPICLGSPEFTDQGRSRSMLEVPRSISVPPSPSDIPPPGPPRVFPPRRPHTPAERVTVKPPDQRRSVDISLGDSPRRARGHAVKNSSHVDRRSMPSMGYMTHTVSAPSLHGKSADDTYLQLKKDLEYLDLKMTGRDLLKDRSLKPVKIAESDTDVKLSIFCEQDRVLQDLEDKIRALKENKDQLESVLEVLHRQMEQYRDQPQHLEKIAYQQKLLQEDLVHIRAELSRESTEMENAWNEYLKLENDVEQLKQTLQEQHRRAFFFQEKSQIQKDLWRIEDVTAGLSANKENFRILVESVKNPERKTVPLFPHPPVPSLSTSESKPPPQPSPPTSPVRTPLEVRLFPQLQTYVPYRPHPPQLRKVTSPLQSPTKAKPKVQEDEAPPRPPLPELYSPEDQPPAVPPLPREATIIRHTSVRGLKRQSDERKRDRELGQCVNGDSRVELRSYVSEPELATLSGDMAQPSLGLVGPESRYQTLPGRGLSGSTSRLQQSSTIAPYVTLRRGLNAESSKATFPRPKSALERLYSGDHQRGKMSAEEQLERMKRHQKALVRERKRTLGQGERTGLPSSRYLSRPLPGDLGSVC
InterPro domains: - IPR057971: Pleckstrin homology domain-containing family A member 4-7, TBCA domain (domain) [316-453]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhesion), GO:0098609 (cell-cell adhesion), GO:0098742 (cell-cell adhesion via plasma-membrane adhesion molecules), GO:0016339 (calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules), GO:0007156 (homophilic cell adhesion via plasma membrane adhesion molecules)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0030054 (cell junction), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit) (P04574)
Organism: Sus scrofa (Pig)
Function: Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Essential for embryonic development (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Translocates to the plasma membrane upon calcium binding. {ECO:0000250}.
Sequence: MFLVNSFLKGGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESEEVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQAIYKQFDVDRSGTIGSSELPGAFEAAGFHLNEHLYSMIIRRYSDEGGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS
InterPro domains: - IPR011992: EF-hand domain pair (homologous_superfamily) [47-264]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [180-192]
- IPR002048: EF-hand domain (domain) [167-266]
Interaction partners: - Calpain-1 catalytic subunit
- Cytochrome b-c1 complex subunit 1, mitochondrial
- Calpastatin
- Calpain-6
- Calpain-5
- Calpain-2 catalytic subunit
- Calpain 8
- Calpain 14
- Calpain-7
- Calpain-13
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:1901575 (organic substance catabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0009057 (macromolecule catabolic process), GO:0030163 (protein catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: GHMYB25 (Q9ATD4)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MGRSPCCEKVGLKKGPWTPEEDQKLLAYIEQHGHGSWRALPLKAGLQRCGKSCRLRWINYLRPDIKRGKFSLQEEQTIIQLHALLGNRWSAIATHLPKRTDNEIKNYWNTHLKKRLTKMGIDPVTHKPKTDALGSTTGNPIDAANLSHMAQWESARLEAEARLVRESKLVPSNPPQSNHFTAVAPSPTPATRPQCLDVLKAWQGVVCGLFTFNMDNNNLQSPTSTLNFMENTTTLPMSSSSSVNGMFNENFGWNSSINPCESGDILKVEYGSDQIPELKERLDHPMELHEMDCSSEGTWFQELFGFNGL
InterPro domains: - IPR017930: Myb domain (domain) [9-116]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [11-108]
- IPR001005: SANT/Myb domain (domain) [9-114]
- IPR015495: Myb transcription factor, plants (family) [1-217]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0071554 (cell wall organization or biogenesis), GO:0009791 (post-embryonic development), GO:0048316 (seed development), GO:0090376 (seed trichome differentiation), GO:0048608 (reproductive structure development), GO:0071669 (plant-type cell wall organization or biogenesis), GO:0044085 (cellular component biogenesis), GO:0009888 (tissue development), GO:0042546 (cell wall biogenesis), GO:0030154 (cell differentiation), GO:0090379 (secondary cell wall biogenesis involved in seed trichome differentiation), GO:0048731 (system development), GO:0090558 (plant epidermis development), GO:0061458 (reproductive system development), GO:0010026 (trichome differentiation), GO:0009832 (plant-type cell wall biogenesis), GO:0010154 (fruit development), GO:0009834 (plant-type secondary cell wall biogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)