Protein: TANK protein (Q6NW12)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKSQLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQPQDKVISGIAREKLPKVRRQEVSSPRKETSARSLGSPLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATETQCSVPIQCTDKTDKQEALFKPQAKDDINRGAPSITSVTPRGLCRDEEDTSFESLSKFNVKFPPMDNDSTFLHSTPERPGILSPATSEVVCQEKFNMEFRDNPGNFVKTEETLFEIQGIDPIASAIQNLKTTDKTKPSNLVNTCIRTTLDRAACLPPGDHNALYVNSFPLLDPSDAPFPSLDSPGKAIRGPQQPIWKPFPNQDSDSVVLSGTDSELHIPRVCEFCQAVFPPSITSRGDFLRHLNSHFNGET
InterPro domains: - IPR041641: CALCOCO1/2, zinc finger UBZ1-type (domain) [393-420]
- IPR039669: TRAF family member-associated NF-kappa-B activator (family) [1-425]
- IPR024581: Tbk1/Ikki binding domain (domain) [133-186]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0016787 (hydrolase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0008233 (peptidase activity), GO:0061134 (peptidase regulator activity), GO:0019899 (enzyme binding), GO:0008047 (enzyme activator activity), GO:0044389 (ubiquitin-like protein ligase binding), GO:0016504 (peptidase activator activity), GO:0008234 (cysteine-type peptidase activity), GO:0019783 (ubiquitin-like protein peptidase activity), GO:0031625 (ubiquitin protein ligase binding), GO:0101005 (deubiquitinase activity), GO:0004843 (cysteine-type deubiquitinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0009628 (response to abiotic stimulus), GO:0023057 (negative regulation of signaling), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0009893 (positive regulation of metabolic process), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0065009 (regulation of molecular function), GO:0006950 (response to stress), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050790 (regulation of catalytic activity), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0044093 (positive regulation of molecular function), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0009314 (response to radiation), GO:0009966 (regulation of signal transduction), GO:0060255 (regulation of macromolecule metabolic process), GO:0010033 (response to organic substance), GO:0104004 (cellular response to environmental stimulus), GO:0010646 (regulation of cell communication), GO:0033554 (cellular response to stress), GO:0070887 (cellular response to chemical stimulus), GO:0071214 (cellular response to abiotic stimulus), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0071478 (cellular response to radiation), GO:0034097 (response to cytokine), GO:0006974 (cellular response to DNA damage stimulus), GO:0051246 (regulation of protein metabolic process), GO:0071310 (cellular response to organic substance), GO:0051336 (regulation of hydrolase activity), GO:1902532 (negative regulation of intracellular signal transduction), GO:0051247 (positive regulation of protein metabolic process), GO:0043085 (positive regulation of catalytic activity), GO:0010212 (response to ionizing radiation), GO:1902531 (regulation of intracellular signal transduction), GO:0030162 (regulation of proteolysis), GO:0031399 (regulation of protein modification process), GO:0070555 (response to interleukin-1), GO:0071479 (cellular response to ionizing radiation), GO:0052547 (regulation of peptidase activity), GO:0071345 (cellular response to cytokine stimulus), GO:0045862 (positive regulation of proteolysis), GO:0043122 (regulation of I-kappaB kinase/NF-kappaB signaling), GO:0043124 (negative regulation of I-kappaB kinase/NF-kappaB signaling), GO:0034612 (response to tumor necrosis factor), GO:0051345 (positive regulation of hydrolase activity), GO:0031401 (positive regulation of protein modification process), GO:0010952 (positive regulation of peptidase activity), GO:1903320 (regulation of protein modification by small protein conjugation or removal), GO:1903322 (positive regulation of protein modification by small protein conjugation or removal), GO:0071347 (cellular response to interleukin-1), GO:0071356 (cellular response to tumor necrosis factor)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)