Protein: histidine kinase (EC 2.7.13.3) (O52237)
Organism: Myxococcus xanthus
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MAHNGSIGGHADMSSGRGINRCQGTEGDEPLSEAVVVLRNVRSAVGGIVDFECVSANVHAERWLGGEEGSLVHNRLLEEAPWAWDGGLFSACVRVVTRRAPEIARVSRQSPMGTVWLLARVSPCDDGVVLFLEDLTERMAAEEALRRDHDLLHAVIESATDAIYVKDVSGRYILINPATASAFHRAPREILGRTDAELLGADRAAPTLAHDREVMSSGHTATYEGAEGGPGTDRIWHTTKGVLRRGDGTVYGLFAICRDVTARRRQELEREEEARFQERFIGVLGHDLGNPLAAVRLSSAALLARDTLPPEVRRVVARIDGSAERMARLVKQLLDFTRARMAGGIPLRPHEVCMEDVCRRIISELEPAHPECCVRLEVDGESRGIWDEERLGQVLSNLLGNALQHSPEGSSVRVRLAAKDSLFQRVEVHNGGPPIPESLRPRLFSPFHGVPPEPGQPKPKHQGLGLGLYIVSQIVTAHGGWLDVASSADTGTCFSVTLPRVTRPLGGPPGKTA
InterPro domains: - IPR036890: Histidine kinase/HSP90-like ATPase superfamily (homologous_superfamily) [332-501]
- IPR052545: Light-responsive regulatory protein (family) [130-500]
- IPR003594: Histidine kinase/HSP90-like ATPase domain (domain) [386-502]
- IPR000014: PAS domain (domain) [148-268]
- IPR005467: Histidine kinase domain (domain) [283-502]
- IPR036097: Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily (homologous_superfamily) [266-339]
- IPR013656: PAS fold-4 (domain) [157-265]
- IPR004358: Signal transduction histidine kinase-related protein, C-terminal (domain) [374-499]
- IPR003661: Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (domain) [276-342]
- IPR035965: PAS domain superfamily (homologous_superfamily) [51-261]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140299 (small molecule sensor activity), GO:0000155 (phosphorelay sensor kinase activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016775 (phosphotransferase activity, nitrogenous group as acceptor), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004673 (protein histidine kinase activity), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0006793 (phosphorus metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0035556 (intracellular signal transduction), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:0006796 (phosphate-containing compound metabolic process), GO:0043412 (macromolecule modification), GO:0000160 (phosphorelay signal transduction system), GO:0016310 (phosphorylation), GO:0006468 (protein phosphorylation), GO:0046777 (protein autophosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)