wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: RING finger protein nhl-1 (Q03601)
Organism: Caenorhabditis elegans
Function: Not known
Sequence: MSSSPQNEAEAREKMRELMSRPPSSRPADFVNPLEKIEQLLTCPICLDRYKQPKLLPCQHTFCYPCLESCADTLHRNLKCPECRAEHNIPYDGVKAFQPNYTLTGFLEIHLQATPESAAEIEEYIHRYNLERCKICDEKADCEPCAHCDRKACKECRQTHMDMLKRDMSRLLNQVKRLANRITEASDNLSKGVDMMTMNCETTKAEIKEYFHRYQRDLKKKEDNFLMEVDTFQATETRNMSNLRDVLEIESSNMSEAVSRLDAAIKGECSIEDSELVRMKNTFTEGLEYLRNFQPDADELFNRKLRFSAGDDAAKLPAAITTSGELCVLVPQFSGRYLPLEQSYLPRPFRLPLESDSYRVKSDERASMRDREADRTSSRHSHRNPEPDESSIRYRRRQQLEDEAWNRLRNSSAAPSLLTTSVTADSSSRTSPWAADRVTRSVEPTKSRPTSLIVPNTETPRTVSPASKPPLPPQSVERVERTEDASPAPLPQLPIRKPPLPRQQSSNDDSLNEKVETIRRAHQQRQDASRAASRAVSSEESEGEDFPVSTNRGRIRIVCRAASVNRDDGLMSMIPGTGTIINVPPPQHQLPASAPITNGTSEQVAIPVTHFTGEEDESDIVVPAWLQRRRQRFQRSRTNPDIQAQFTSARVQQLLAERQSRLDSSTTTDEEKEKLAVLRQRGRSASREAGEWRARGRPRAVFGRKGAKDGELNWPRGICALSGGLVATCDSSNHRVCVFDKDGKFVRQFGGYGAGAGQLDSAAGLASSKLRVIVSDRYNHRISVFGLEGDHLFSFGGHGQGNAKFNNPWGVAVDDLGSIYVADKDNHRVQVFDKNGQFIAKFGSFGHLPGQLNSPLFIAVSRVTHHVYVSDSSNHRISVFDPHGVHLFSFGEEGFHGGQFKFPRGIAIDSQENLIIADSGNNRIQVFDAQGQFVSSFGTWGGGAGQLKGVEDVCVTADGSIVVTDRENHRIQIF
InterPro domains: - IPR017907: Zinc finger, RING-type, conserved site (conserved_site) [58-67]
- IPR011042: Six-bladed beta-propeller, TolB-like (homologous_superfamily) [692-974]
- IPR001258: NHL repeat (repeat) [699-974]
- IPR050952: Tripartite Motif and NHL Repeat Containing E3 Ligases (family) [177-974]
- IPR018957: Zinc finger, C3HC4 RING-type (domain) [43-83]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [1-116]
- IPR001841: Zinc finger, RING-type (domain) [43-84]
Interaction partners: - PH domain-containing protein
- Ubiquitin-conjugating enzyme E2 13
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0050789 (regulation of biological process), GO:0051641 (cellular localization), GO:0033036 (macromolecule localization), GO:0050794 (regulation of cellular process), GO:0070727 (cellular macromolecule localization), GO:0051128 (regulation of cellular component organization), GO:0044087 (regulation of cellular component biogenesis), GO:0033043 (regulation of organelle organization), GO:0008104 (protein localization), GO:1902115 (regulation of organelle assembly), GO:1902117 (positive regulation of organelle assembly), GO:0033365 (protein localization to organelle), GO:0051493 (regulation of cytoskeleton organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030017 (sarcomere), GO:0005737 (cytoplasm), GO:0036379 (myofilament), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043292 (contractile fiber), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0030016 (myofibril), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0032982 (myosin filament)
Protein: Bacterioferritin (BFR) (EC 1.16.3.1) (Cytochrome b-1) (Cytochrome b-557) (P0ABD3)
Organism: Escherichia coli (strain K12)
Function: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. The mineralized iron core can contain as many as 2700 iron atoms/24-meric molecule.
Sequence: MKGDTKVINYLNKLLGNELVAINQYFLHARMFKNWGLKRLNDVEYHESIDEMKHADRYIERILFLEGLPNLQDLGKLNIGEDVEEMLRSDLALELDGAKNLREAIGYADSVHDYVSRDMMIEILRDEEGHIDWLETELDLIQKMGLQNYLQAQIREEG
InterPro domains: - IPR002024: Bacterioferritin (family) [1-157]
- IPR009040: Ferritin-like diiron domain (domain) [1-145]
- IPR012347: Ferritin-like (homologous_superfamily) [1-158]
- IPR008331: Ferritin/DPS domain (domain) [8-144]
- IPR009078: Ferritin-like superfamily (homologous_superfamily) [1-157]
Interaction partners: - Bacterioferritin-associated ferredoxin
- Ferrochelatase
- Bacterial non-heme ferritin
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0016491 (oxidoreductase activity), GO:0042802 (identical protein binding), GO:0043169 (cation binding), GO:0016722 (oxidoreductase activity, acting on metal ions), GO:0016724 (oxidoreductase activity, acting on metal ions, oxygen as acceptor), GO:0046872 (metal ion binding), GO:0046914 (transition metal ion binding), GO:0004322 (ferroxidase activity), GO:0005506 (iron ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0033554 (cellular response to stress), GO:0006974 (cellular response to DNA damage stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: LD07444p (Q8T0E8)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MCTLHPEEEAHLMAMASGGQPTRTASPRPLVTASIAAPRSLFDVCWDDVLIPQVAVYLSLKDLFNLRCCSRTAQRFVEAALEKRQELHLSGNNTKNIDVAFRVLARCCQRLEVLHLACCRWLTDELLLPLLANNKKRLWAVNLNECVNITALSLQPIIVECKELRVLKLSKCQWLTTGAVDALTLHQSKLVEFDISYCGAIGERCLIIFFRKLNKLTVLSLANTPSVTHQVLIQIGNYCRELEHINVIGCAAISDYGVHALTVHCLRLRTLLIRRCPRVTELSLAPLRQRRLYIDRPQPDVGLNAYNLNDFYPSDFLVY
InterPro domains: - IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [52-295]
- IPR006553: Leucine-rich repeat, cysteine-containing subtype (repeat) [108-290]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048511 (rhythmic process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0042752 (regulation of circadian rhythm), GO:0007610 (behavior), GO:0007623 (circadian rhythm), GO:0009649 (entrainment of circadian clock), GO:0048512 (circadian behavior), GO:0009314 (response to radiation), GO:0007622 (rhythmic behavior), GO:0007626 (locomotory behavior), GO:0009416 (response to light stimulus), GO:0045475 (locomotor rhythm), GO:0043153 (entrainment of circadian clock by photoperiod), GO:0009648 (photoperiodism)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0140535 (intracellular protein-containing complex), GO:1990234 (transferase complex), GO:0000151 (ubiquitin ligase complex), GO:0031461 (cullin-RING ubiquitin ligase complex), GO:0019005 (SCF ubiquitin ligase complex)
Protein: 60S ribosomal protein L21 (Q9V9M7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MTNSKGYRRGTRDMFSRPFRKHGVIPLSTYMRVFKIGDIVDIKGHGAVQKGLPYKAYHGKTGRIFNVTQHAVGVIVNKRVRGKILAKRVNVRIEHIHHSKCREDFLRRVKENERLLKEAKEKGQWVSLKRQPEQPKKAHFVKKLEEPIALAPIPYEFIA
InterPro domains: - IPR008991: Translation protein SH3-like domain superfamily (homologous_superfamily) [2-100]
- IPR036948: Large ribosomal subunit protein eL21 superfamily (homologous_superfamily) [1-98]
- IPR018259: Large ribosomal subunit protein eL21, conserved site (conserved_site) [37-62]
- IPR001147: Large ribosomal subunit protein eL21 (family) [1-158]
Interaction partners: - Small ribosomal subunit protein uS13
- GEO07453p1
- Large ribosomal subunit protein eL33
- Large ribosomal subunit protein uL18
- Small ribosomal subunit protein eS17
- Large ribosomal subunit protein uL14
- Small ribosomal subunit protein uS7A
- Small ribosomal subunit protein uS10
- Large ribosomal subunit protein uL4
- Small ribosomal subunit protein uS4
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0003735 (structural constituent of ribosome)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0019538 (protein metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006412 (translation), GO:0009059 (macromolecule biosynthetic process), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:0006518 (peptide metabolic process), GO:0010467 (gene expression), GO:0043043 (peptide biosynthetic process), GO:0002181 (cytoplasmic translation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0044391 (ribosomal subunit), GO:0043229 (intracellular organelle), GO:0022626 (cytosolic ribosome), GO:0043228 (non-membrane-bounded organelle), GO:0015934 (large ribosomal subunit), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0022625 (cytosolic large ribosomal subunit), GO:0005840 (ribosome)
Protein: MIP16848p (Q9VQ14)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MNIRVIILLFCLIVFVGGKKVHRFRLERRSHRHHKIPHAHLHLQFRNALRRKYGFTPLRTVNAVNVTSESGKGVVITEPLINSYDTNFFGVVSVGDQSFTMQFDTGSSDFWVPSSHCRFCIKTCGNKFFRKSNSKSFRSSGTPFSITYGSGSVKGIVASDNVGFGDLKIQNQGIGLVNISDSCSVFDGIAGFAFQQLSMTKSVPSFQQMIDQQLVEQPIFSFHLKSGSSDGGSMILGGSNSSLYYGPLTYTNVTEAKYWSFKLDFIAVHGKGSRSSRTGNKAIMDTGTSLIVGPVLEVLYINKDIGAEHNKTYNLYTVACESIPQLPIIVFGIAGKEFFVKPHTYVIRYDNFCFSAFMDMLGLQYWILGDAFMRENYVEFDWARRRMGIAPAV
InterPro domains: - IPR033121: Peptidase family A1 domain (domain) [88-392]
- IPR021109: Aspartic peptidase domain superfamily (homologous_superfamily) [8-392]
- IPR001461: Aspartic peptidase A1 (family) [60-390]
Interaction partners: - Cathepsin B, isoform A)
- Cathepsin L1
- cathepsin L
- FI04419p
- Cathepsin F
- Uncharacterized protein, isoform A
- IP19042p
- Peptidase A1 domain-containing protein
- Uncharacterized protein, isoform B
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0008233 (peptidase activity), GO:0004175 (endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0042742 (defense response to bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0005576 (extracellular region), GO:0005773 (vacuole), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0005764 (lysosome)
Protein: Hydroxycarboxylic acid receptor 2 (G-protein coupled receptor 109A) (G-protein coupled receptor HM74A) (Niacin receptor 1) (Nicotinic acid receptor) (Q8TDS4)
Organism: Homo sapiens (Human)
Function: Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis. The rank order of potency for the displacement of nicotinic acid binding is 5-methyl pyrazole-3-carboxylic acid = pyridine-3-acetic acid > acifran > 5-methyl nicotinic acid = acipimox >> nicotinuric acid = nicotinamide.
Subcellular location: Cell membrane {ECO:0000269|PubMed:17932499}; Multi-pass membrane protein {ECO:0000269|PubMed:17932499}.
Sequence: MNRHHLQDHFLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVFVICFLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKMTGEPDNNRSTSVELTGDPNKTRGAPEALMANSGEPWSPSYLGPTSP
InterPro domains: - IPR051893: Hydroxycarboxylic Acid Receptors (family) [14-338]
- IPR017452: GPCR, rhodopsin-like, 7TM (domain) [44-294]
- IPR000276: G protein-coupled receptor, rhodopsin-like (family) [29-302]
Interaction partners: - Hydroxycarboxylic acid receptor 3
- Density-regulated protein
- Pro-neuropeptide Y
- Sodium-coupled monocarboxylate transporter 1
- Free fatty acid receptor 2
- Appetite-regulating hormone
- Succinate receptor 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004930 (G protein-coupled receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007186 (G protein-coupled receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction)
Protein: Tripartite motif-containing protein 73 (Tripartite motif-containing protein 50B) (Q86UV7)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MAWQVSLLELEDRLQCPICLEVFKESLMLQCGHSYCKGCLVSLSYHLDTKVRCPMCWQVVDGSSSLPNVSLAWVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHHPVTPVSTVCSRMKEELAALFSELKQEQKKVDELIAKLVKNRTRIVNESDVFSWVIRREFQELRHPVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHEFIWKFHSMASR
InterPro domains: - IPR017907: Zinc finger, RING-type, conserved site (conserved_site) [31-40]
- IPR050143: Tripartite motif-containing (family) [12-230]
- IPR000315: B-box-type zinc finger (domain) [84-125]
- IPR027370: Zinc finger, RING-type, eukaryotic (domain) [16-54]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [3-80]
- IPR001841: Zinc finger, RING-type (domain) [16-56]
Interaction partners: - Gamma-butyrobetaine dioxygenase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0065009 (regulation of molecular function), GO:0019222 (regulation of metabolic process), GO:0009892 (negative regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0050790 (regulation of catalytic activity), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0044092 (negative regulation of molecular function), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0043086 (negative regulation of catalytic activity), GO:0051246 (regulation of protein metabolic process), GO:0051336 (regulation of hydrolase activity), GO:0051248 (negative regulation of protein metabolic process), GO:0052547 (regulation of peptidase activity), GO:0045861 (negative regulation of proteolysis), GO:0051346 (negative regulation of hydrolase activity), GO:0030162 (regulation of proteolysis), GO:0052548 (regulation of endopeptidase activity), GO:0010466 (negative regulation of peptidase activity), GO:0010951 (negative regulation of endopeptidase activity), GO:2000116 (regulation of cysteine-type endopeptidase activity), GO:2000117 (negative regulation of cysteine-type endopeptidase activity)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Ligase IV-alpha (Q56AN9)
Organism: Trypanosoma brucei
Function: Not known
Sequence: MWRISNLWRRPQLTTLPKDPSLFFGVGRPRTPEQVERYHAMKNTTIESAFPHLAACWVGPSWGTVMLTPHHVAPTCVKSAVWRCSQCLQEFEMSIARFIDQHGTCPLCGKEQRRISSTRNEGPERINGKMSEGDNTDVGITTSPTDATNEEDLELEDVNSLRAPRMTHTNYKSVLHSNPEWEGRNILPMLAQRWELVAEELLHPADTEEQESLLVSPKIDGIRCLIGYNKSQKKLQFFSRSGILLECCHGLVPHAMPLFKADPSLLLDGELFAPHCGFERLSGLVRRLEKFTTQTTRRKQAKLLEYFAFDIMASDQLSSPDAPFSERYRLLKELIPHSGADRVFDTMKPNGRRNHQLEKEELSSRKKIPKLYHVPATLVSPDEVESVLEKACSQGYEGVIIRRPKFPYEHGKRSLGLLKYKYMHDAEYRIVDFLPGNGKFEGGLGAFVCETSTGIRFNATPKTTTKRRLELWAERDRLLGKYLTVQYQELSSQDVPRFPIAKCVRGESEKDWL
InterPro domains: - IPR012310: DNA ligase, ATP-dependent, central (domain) [188-453]
- IPR016059: DNA ligase, ATP-dependent, conserved site (conserved_site) [397-421]
- IPR025487: Treble clef zinc finger domain (domain) [66-110]
- IPR050326: NAD-dependent DNA ligase B (family) [80-508]
- IPR029319: DNA ligase, OB-like domain (domain) [435-505]
- IPR012340: Nucleic acid-binding, OB-fold (homologous_superfamily) [394-509]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016874 (ligase activity), GO:0016886 (ligase activity, forming phosphoric ester bonds), GO:0140097 (catalytic activity, acting on DNA), GO:0003909 (DNA ligase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0140053 (mitochondrial gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0000963 (mitochondrial RNA processing), GO:0000959 (mitochondrial RNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0020023 (kinetoplast), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: C6orf182 protein (Centrosomal protein 57 like 1) (Chromosome 6 open reading frame 182, isoform CRA_c) (Q6P2R3)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MDSELMHSIVGSYHKPPERVFVPSFTQNEPSQNCHPANLEVTSPKILHSPNSQALILALKTLQEKIHRLELERTQAEDNLNILSREAAQYKKALENETNERNLAHQELIKQKKDISIQLSSAQSRCTLLEKQLEYTKRMVLNVEREKNMILEQQAQLQREKEQDQMKLYAKLEKLDVLEKECFRLTTTQKTAEDKIKHLEEKLKEEEHQRKLFQDKASELQTGLEISKIIMSSVSNLKHSKEKKKSSKVCI
InterPro domains: - IPR051756: Centrosomal microtubule-associated protein (family) [2-248]
- IPR025913: Cep57 centrosome localisation domain (domain) [54-231]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0007017 (microtubule-based process), GO:0022402 (cell cycle process), GO:0007049 (cell cycle), GO:0016043 (cellular component organization), GO:0000226 (microtubule cytoskeleton organization), GO:0007059 (chromosome segregation), GO:0044085 (cellular component biogenesis), GO:0007051 (spindle organization), GO:0051225 (spindle assembly), GO:0006996 (organelle organization), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0007010 (cytoskeleton organization), GO:0140694 (non-membrane-bounded organelle assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: PSP1 C-terminal domain-containing protein (Q38A41)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MEHEIHKGMEAIVEQSGDNRASGEVNAESNVHSPASVTAKDGCEFARRRISTRGIRGSVRSPYYSPTRSSAMSPVGNGEKGDQEKEEGEGAAEPDVVPDIDVIPRYRSHPNRSQGSFSHLTYNVHSPAHSRMSSYERISWDSQAWKDVFPENAFLGDQSKDLLRLPHSSMDFYHGSPTQQCRKHVRSLATWGKVEGDGSPELLATRNSSPMRPAGCQSLVSTLDALPEPIYETAPLGHQHCFSLSSRKDAAYLKTEAGGEATAVTNEAGEQPSKGPAMTHVLVAFKSLYGVYYVPEAQWGTIGIGDLVSVESHSGENTGKVICDLTHIMSEASHMPAEMAQCPRHVLWPEDASAPLETINPKTNEEVLQRLPRVLRRGMNKGKKRLYYARRRENEALDVGNRLVRDRNFNLALTSVEYQVDFKRITVFCKGDRSHVDPSEVLIFSQQLASSLRGSIVSVVFANEIPERLDVTGSITKAAFQDIYTDALAKIKEAESAQPQRQASSSPVRQSTTAAGGPHNNMRASHIYPDPQLAAMNHTPLMPFYGVPPPFSPPVAPGAPPLMNAVGMNGLYGMTGVPPMNWGMPTPPPYIPPHLPQNVPGRM
InterPro domains: - IPR047767: PSP1-like (family) [58-456]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)