wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: RE19601p (Q8SXJ5)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MNEDHLEDTHLCIRCNATILGLSKYIDHRKRNCLITGKQNASPKTDGRTRISADTHVSATLISSSNLDHSYDGFHFTEPEAPSSYLRKTAASHGGKTSKSLTEAYDLPYELGADLFFSSLQLQSVATGGKIGSVPRQERSKDESWSAPAGDPLLKAVRENDETVFKPLHFDHEYPEASDEEDDEDEHEEFDAEEDEEEYDARRHSPPIVPASHTGGKWKPEQRPQLRHPHIERLSPSWDEPPEENYTHPPADHTKGKWVPGSKQLEYRENLDLTKLDQPGASYWCNICCRRLKSRLYYNQHLRSGYHIKRAEAECELEQATLGRELTLSKDFSIKDDADKNEPKPPKRQRRANLLRCDLCRHTMARHLIGKHLISHYHFRRLQQQSRIRRQACLQEILKHMGSIVRQSPFQCMPCRFYANTEETFLYHWKSHEHLELTKRLGGTFWCSFCQFNSNTNNSMLLHLLDSSHKEVLLALNRSVPICIAQRIRIQCSRCGMEFLYNIQLRQHSITEHPGLALTGTAADEYQSRFRCNLCGSSQKSRLALQRHKKHKHHLARYFCAICRLEFDNSLDARRHRSLVIHKQKARPQTSIPQPENEIEHMLREVLEETVPSPPAKRSADVNAKCSNSRKTIESSQRLAQHQAEVHSSDNHLCLSCGISFESAQALGRHTRSCQPLASTSTPADLSQAQKKSMYSCDQCRFQSQYESDLVYHRIFHTRSGTIGKNEVLQCPLCPKNFKKHSLRAHLRNHTNEKIFECTECLQKFARRHNLKNHVITKHAKVGDKEKKKYAAKDVEQSKPKYQCGTCGKLLAKKYSLKLHEISHSKAVERNYLCHFADCSYAGRTPESLKTHLVSHSQENHKCARINCSYVGKSELHLKRHLKSAHSTEKNGEEWFSCDQCDFRARIKGHLRRHSLRHSGQKPHQCPHCDFQCSTIDNLRKHIIKTGKHPGMFIYHCAKCSDEEAGEIFKSNSYKEYQHHLKTHKAG
InterPro domains: - IPR013087: Zinc finger C2H2-type (domain) [283-984]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [270-943]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0032989 (cellular component morphogenesis), GO:0000902 (cell morphogenesis), GO:0016043 (cellular component organization), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0016358 (dendrite development), GO:0048731 (system development), GO:0022008 (neurogenesis), GO:0048813 (dendrite morphogenesis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0048858 (cell projection morphogenesis), GO:0030182 (neuron differentiation), GO:0032990 (cell part morphogenesis), GO:0048666 (neuron development), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0048699 (generation of neurons), GO:0031175 (neuron projection development), GO:0048812 (neuron projection morphogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Cathepsin Z (EC 3.4.18.1) (L3 cysteine protease) (LOVCP) (Q6PN98)
Organism: Onchocerca volvulus
Function: Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity (By similarity). Plays an essential role in molting, a process during larval stages in which a new cuticle is formed and the old cuticle is shed (Probable). Required for the degradation and shedding of the old cuticle (Probable).
Subcellular location: Cytoplasmic vesicle, secretory vesicle {ECO:0000269|PubMed:8939969}. Secreted {ECO:0000269|PubMed:8939969}. Note=Localizes in secretory vesicles in the hypodermis of L3 larvae. {ECO:0000269|PubMed:8939969}.
Sequence: MLAILFNFFLLTYFTNITLGKVGKSIDLDTRNGYNVHGCYKQTGKIYAHKTYPRQYEAENYNFDDLPVAWDWRNINGVNYASVDRNQHIPQYCGSCWAFGSTSALADRFNIKRKGAWPPAYLSVQEVIDCANAGSCEGGEPGPVYKYAHEFGIPHETCNNYQARDGTCSSYNKCGSCWPGSCFSIKNYTIYRVKNYGAVSGLHKMKAEIYHHGPIACGIAATKAFETYAGGIYNERTNEDIDHIISAHGWGVDSESGVPYWIGRNSWGTPWGENGWFRIVTSEYKNSSSKYNLKIEEDCVWADPIA
InterPro domains: - IPR013128: Peptidase C1A (family) [52-281]
- IPR025661: Cysteine peptidase, asparagine active site (active_site) [260-279]
- IPR000668: Peptidase C1A, papain C-terminal (domain) [66-303]
- IPR038765: Papain-like cysteine peptidase superfamily (homologous_superfamily) [57-283]
- IPR033157: Cathepsin Z (family) [66-305]
Interaction partners: - Uncharacterized protein
- Carboxypeptidase
- Uncharacterized protein
- Uncharacterized protein.
- Peptidase A1 domain-containing protein
- Peptidase A1 domain-containing protein
- Peptidase A1 domain-containing protein
- Peptidase A1 domain-containing protein
- Peptidase A1 domain-containing protein
- Uncharacterized protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008234 (cysteine-type peptidase activity), GO:0004175 (endopeptidase activity), GO:0004197 (cysteine-type endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0016032 (viral process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0019058 (viral life cycle), GO:0044403 (biological process involved in symbiotic interaction), GO:0051701 (biological process involved in interaction with host), GO:0046718 (viral entry into host cell), GO:0044000 (movement in host), GO:0044409 (entry into host)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Type-4 uracil-DNA glycosylase (EC 3.2.2.27) (TTUDGA) (TthUDG) (Q5SKC5)
Organism: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
Function: Removes uracil bases that are present in DNA as a result of either deamination of cytosine or misincorporation of dUMP instead of dTMP. Can remove uracil from double-stranded DNA containing either a U/G, U/A, U/C or U/T base pair as well as from single-stranded DNA. Specifically recognizes uracil that is flipped out from double-stranded DNA.
Sequence: MTLELLQAQAQNCTACRLMEGRTRVVFGEGNPDAKLMIVGEGPGEEEDKTGRPFVGKAGQLLNRILEAAGIPREEVYITNIVKCRPPQNRAPLPDEAKICTDKWLLKQIELIAPQIIVPLGAVAAEFFLGEKVSITKVRGKWYEWHGIKVFPMFHPAYLLRNPSRAPGSPKHLTWLDIQEVKRALDALPPKERRPVKAVSQEPLF
InterPro domains: - IPR051536: Uracil-DNA glycosylase family, Type-4/5 (family) [2-186]
- IPR005122: Uracil-DNA glycosylase-like (domain) [27-179]
- IPR005273: Uracil-DNA glycosylase family 4 (domain) [13-167]
- IPR036895: Uracil-DNA glycosylase-like domain superfamily (homologous_superfamily) [1-205]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016787 (hydrolase activity), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0140097 (catalytic activity, acting on DNA), GO:0016799 (hydrolase activity, hydrolyzing N-glycosyl compounds), GO:0019104 (DNA N-glycosylase activity), GO:0097506 (deaminated base DNA N-glycosylase activity), GO:0004844 (uracil DNA N-glycosylase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0033554 (cellular response to stress), GO:0006259 (DNA metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0006974 (cellular response to DNA damage stimulus), GO:0006281 (DNA repair)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Semaphorin-like protein 139 (Q8JL80)
Organism: Ectromelia virus (strain Moscow) (ECTV) (Mousepox virus)
Function: Acts as a semaphorin-like protein and binds to host plexin C1 receptor. May alter the movement of plexin C1-expressing cells including dendritic cells, monocytes, or granulocytes in the proximity of infected cells. May also regulate host cell cytoskeleton of neighboring cells to improve viral infection.
Subcellular location: Secreted {ECO:0000250}.
Sequence: MIPLLFILFYFTNCIEWHKFETSEEIISTYLIDDVLYTGVNGAVYTFSNNELNKTGLTNNNNYITTSIKVEDTLVCGTNNGNPKCWKIDGSEDPKYRGRGYAPYQNSKVTIISHNECVLSDINISKEGIKRWRRFDGPCGYDLYTADNVIPKDGVRGAFVDKDGTYDKVYILFTDTIDTKRIVKIPYIAQMCLNDEGGPSSLSSHRWSTFLKVELECDIDGRSYRQIIHSKAIKTDNDTILYVFFDSPYSKSALCTYSMNAIKHSFSTSKLGGYTKQLPSPAPGICLPAGKVVPHTTFDIIEQYNELDDIIKPLSQPIFEGPSGVKWFDIKEKENEHREYRIYFIKENTIYSFDTKSKQTRSAQVDARLFSVMVTSKPLFIADIGIGVGIPRMKKILKM
InterPro domains: - IPR027231: Semaphorin (family) [60-319]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [12-399]
- IPR001627: Sema domain (domain) [1-399]
- IPR036352: Sema domain superfamily (homologous_superfamily) [2-360]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030215 (semaphorin receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:0009615 (response to virus), GO:0043207 (response to external biotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Rubisco methyltransferase family protein (Q8VZB5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MEGVITCFHTKCVSLPIRSFPLSRVSSLPRWRNNKLISSSRSVHLRSLCVSSSDTLVASGSPKEDERQSKVSSKKEGDDSEDLKFWMDKNGLPPCKVILKERPAHDQKHKPIHYVAASEDLQKGDVAFSVPDSLVVTLERVLGNETIAELLTTNKLSELACLALYLMYEKKQGKKSVWYPYIRELDRQRGRGQLDAESPLLWSEAELDYLTGSPTKAEVLERAEGIKREYNELDTVWFMAGSLFQQYPFDIPTEAFSFEIFKQAFVAIQSCVVHLQNVGLARRFALVPLGPPLLAYCSNCKAMLTAVDGAVELVVDRPYKAGDPIVVWCGPQPNAKLLLNYGFVDEDNPYDRVIVEAALNTEDPQYQDKRMVAQRNGKLSQQVFQVRVGKEREAVQDMLPYLRLGYMSDPSEMQSVISSQGPVCPMSPCMERAVLDQLANYFMRRLSGYPTTPKEDDALLADPSLSPRKRVATRLVQLEKKILVACLTTTVDLLNQLPDTAISPCPAPYAPSLK
InterPro domains: - IPR015353: Rubisco LSMT, substrate-binding domain (domain) [361-483]
- IPR036464: Rubisco LSMT, substrate-binding domain superfamily (homologous_superfamily) [340-507]
- IPR046341: SET domain superfamily (homologous_superfamily) [80-348]
- IPR050600: SETD3/SETD6 methyltransferase (family) [72-468]
Interaction partners: - ETFB lysine methyltransferase
- Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein
- Chaperonin 60 subunit beta
- Calmodulin-lysine N-methyltransferase
- Protein arginine N-methyltransferase 1.6
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0008276 (protein methyltransferase activity), GO:0016279 (protein-lysine N-methyltransferase activity), GO:0008168 (methyltransferase activity), GO:0008757 (S-adenosylmethionine-dependent methyltransferase activity), GO:0008170 (N-methyltransferase activity), GO:0016278 (lysine N-methyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0032259 (methylation), GO:0006807 (nitrogen compound metabolic process), GO:0043414 (macromolecule methylation), GO:1901564 (organonitrogen compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0019538 (protein metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0006479 (protein methylation), GO:0008213 (protein alkylation), GO:0018022 (peptidyl-lysine methylation), GO:0018193 (peptidyl-amino acid modification), GO:0018205 (peptidyl-lysine modification), GO:0018023 (peptidyl-lysine trimethylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009532 (plastid stroma), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009570 (chloroplast stroma), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle)
Protein: ABC transporter, ATP-binding protein (Q9WYC3)
Organism: Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Sequence: MKTLARYLKPYWIFAVLAPLFMVVEVICDLSQPTLLARIVDEGIARGDFSLVLKTGILMLIVALIGAVGGIGCTVFASYASQNFGADLRRDLFRKVLSFSISNVNRFHTSSLITRLTNDVTQLQNLVMMLLRIVVRAPLLFVGGIVMAVSINVKLSSVLIFLIPPIVLLFVWLTKKGNPLFRKIQESTDEVNRVVRENLLGVRVVRAFRREEYENENFRKANESLRRSIISAFSLIVFALPLFIFIVNMGMIAVLWFGGVLVRNNQMEIGSIMAYTNYLMQIMFSLMMIGNILNFIVRASASAKRVLEVLNEKPAIEEADNALALPNVEGSVSFENVEFRYFENTDPVLSGVNFSVKPGSLVAVLGETGSGKSTLMNLIPRLIDPERGRVEVDELDVRTVKLKDLRGHISAVPQETVLFSGTIKENLKWGREDATDDEIVEAAKIAQIHDFIISLPEGYDSRVERGGRNFSGGQKQRLSIARALVKKPKVLILDDCTSSVDPITEKRILDGLKRYTKGCTTFIITQKIPTALLADKILVLHEGKVAGFGTHKELLEHCKPYREIYESQFGNGVMNDA
InterPro domains: - IPR017871: ABC transporter-like, conserved site (conserved_site) [470-484]
- IPR036640: ABC transporter type 1, transmembrane domain superfamily (homologous_superfamily) [1-317]
- IPR003593: AAA+ ATPase domain (domain) [358-544]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [321-573]
- IPR039421: Type 1 protein exporter (family) [2-568]
- IPR003439: ABC transporter-like, ATP-binding domain (domain) [332-567]
- IPR011527: ABC transporter type 1, transmembrane domain (domain) [16-298]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0140352 (export from cell), GO:0140115 (export across plasma membrane), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:0015833 (peptide transport), GO:0042886 (amide transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: ADP-ribosylation factor like GTPase 13B (A0A8I5ZXD0)
Organism: Rattus norvegicus (Rat)
Function: Not known
Sequence: MFNLMANCCNLFKRWREPVRKVTLVMVGLDNAGKTATAKGIQGEHPEDVAPTVGFSKIDLRQGKFEVTIFDLGGGKRIRGIWKNYYAESYGVIFVVDSSDEDRMEETKETMSEVLRHPRISGKPILVLANKQDKEGALGEADVIECLSLEKLVNEHKCLCQIEPCSAVLGYGKKIDKSIKKGLYWLLHIIAKDFDALSERIQKDTTEQRALEEQEKCERAERVRKLREEREQEQTELDGTSGLAEMDSGPVLTNPFQPIAAVIIENEKKQEKEKKKKTAEKDSDVGHPEHKGEQEGAESQNEAGGCLRNPHRDVVNSYKEALSQQLDNEDELDQRVSEPGDNSKKKTKKLRMKRSHRVEPVNTDESAPKSPTPPPPPPPDFYGKPLPPLAVRQRPNGDAQDMIS
InterPro domains: - IPR006689: Small GTPase superfamily, ARF/SAR type (family) [2-190]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [19-226]
- IPR005225: Small GTP-binding domain (domain) [22-141]
- IPR051995: Ciliary function-associated GTPase (family) [1-381]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:1901700 (response to oxygen-containing compound), GO:0010035 (response to inorganic substance), GO:1902074 (response to salt), GO:0010038 (response to metal ion), GO:0010226 (response to lithium ion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0042995 (cell projection), GO:0098794 (postsynapse), GO:0036477 (somatodendritic compartment), GO:0030054 (cell junction), GO:0043197 (dendritic spine), GO:0120025 (plasma membrane bounded cell projection), GO:0097447 (dendritic tree), GO:0045202 (synapse), GO:0043005 (neuron projection), GO:0030425 (dendrite), GO:0044309 (neuron spine)
Protein: Hsp70-Hsp90 organizing protein 1 (AtHop1) (Stress-induced-phosphoprotein 1) (STI1) (Q9LNB6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mediates the association of the molecular chaperones HSP70 and HSP90. Mediates nuclear encoded chloroplast preproteins binding to HSP90 prior to chloroplastic sorting (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Sequence: MAEEAKAKGNAAFSSGDFTTAINHFTEAIALAPTNHVLFSNRSAAHASLHQYAEALSDAKETIKLKPYWPKGYSRLGAAHLGLNQFELAVTAYKKGLDVDPTNEALKSGLADAEASVARSRAAPNPFGDAFQGPEMWTKLTSDPSTRGFLQQPDFVNMMQEIQKNPSSLNLYLKDQRVMQSLGVLLNVKFRPPPPQGDEAEVPESDMGQSSSNEPEVEKKREPEPEPEPEVTEEKEKKERKEKAKKEKELGNAAYKKKDFETAIQHYSTAIEIDDEDISYLTNRAAVYLEMGKYNECIEDCNKAVERGRELRSDYKMVARALTRKGTALTKMAKCSKDYEPAIEAFQKALTEHRNPDTLKRLNDAERAKKEWEQKQYFDPKLGDEEREKGNDFFKEQKYPEAIKHYTEAIKRNPNDHKAYSNRAASYTKLGAMPEGLKDAEKCIELDPTFSKGYSRKAAVQFFLKEYDNAMETYQAGLEHDPSNQELLDGVKRCVQQINKANRGDLTPEELKERQAKGMQDPEIQNILTDPVMRQVLSDLQENPSAAQKHMQNPMVMNKIQKLISAGIVQMK
InterPro domains: - IPR041243: STI1/HOP, DP domain (domain) [134-565]
- IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [1-496]
- IPR019734: Tetratricopeptide repeat (repeat) [2-484]
- IPR006636: Heat shock chaperonin-binding (domain) [133-560]
Interaction partners: - Heat shock 70 kDa protein 4
- Meiosis-specific protein ASY1
- Meiosis-specific protein ASY3
- Heat shock protein 90-1
- Meiotic recombination protein DMC1 homolog
- Mitotic spindle checkpoint protein MAD2
- Heat shock protein 90-5, chloroplastic
- Co-chaperone protein p23-1
- Peptidyl-prolyl cis-trans isomerase CYP40
- Cytochrome P450 83B1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0031072 (heat shock protein binding), GO:0051879 (Hsp90 protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0010035 (response to inorganic substance), GO:0010038 (response to metal ion), GO:0046686 (response to cadmium ion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: protein-serine/threonine phosphatase (EC 3.1.3.16) (A0A1D8PRZ8)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Sequence: MGQILSQPVVEKHSDEHKDKYLAYGISCMQGWRINMEDAHATILNLYDLPLKKSLSSNSEQDEDEEDEEEEADSQDSTTTNTTKSQQQQNQKEDLQQNNDKQNSQQDIKDGDNDTQMSDSDENHHHAAPQQQHIAFFGVYDGHGGEKAAIFTGEKLHHLIKETKEFKQKDYINALKQGFLNCDQEILKDFYMRDDDSGCAATSAIITPDLIVCGNAGDSRTIMSTNGFAKALSFDHKPSNEGEKARICAAGGYVDMGRVNGNLALSRGIGDFDFKKNVDLPAEEQIVTCYPDVIQHNIDYKSDEFVVLACDGIWDCLTSQKCVECVRRGIYERKSLSIICEEIMDLCCAPTSDGSGIGCDNMSIAIVALLDYTKNETLDQWYEKIISRVEQQQQQKNDPNSLNKYGPISQPYNELYKEMYGEYYDIGQQGQGGNGRSNIGSGSGRGSGASGSSSGGGASINGNSIFGRSGYDDEDDDDEEKNIERRRRDQDESNLNGGAISLQKLLASNAITNENGVIYLDTSSAQSLLAHFGVADAGAHGDEEDEEEEGEDVHQGLAHEEEEEEEKEGSKIEEISEKIDDEV
InterPro domains: - IPR036457: PPM-type phosphatase-like domain superfamily (homologous_superfamily) [1-369]
- IPR000222: PPM-type phosphatase, divalent cation binding (binding_site) [136-144]
- IPR015655: Protein phosphatase 2C (family) [88-365]
- IPR001932: PPM-type phosphatase-like domain (domain) [13-369]
Interaction partners: - Serine/threonine-protein phosphatase
- Polyamine acetyltransferase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0004721 (phosphoprotein phosphatase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0004722 (protein serine/threonine phosphatase activity), GO:0016791 (phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0030447 (filamentous growth)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062039 (biofilm matrix), GO:0062040 (fungal biofilm matrix)