wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Lysozyme 1 (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase) (Q27650)
Organism: Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM)
Function: Has antibacterial activity against Gram-positive bacteria. No activity against S.aureus. Does not appear to have chitinase activity.
Subcellular location: Cytoplasmic granule {ECO:0000269|PubMed:7649184}.
Sequence: MFALFLCIALASAKLGIDVSQPTSTSSFTCLRNKGFTTMVIVRAWKSTGSFDTNAPQTLKNANAAGFSIENSDVYYYPCISCGNMAGQVRTFWQKVGQYSLKVKRVWFDIEGTWTSSVSTNQNYLMQMMNEARAIGIVHGIYGSKYYWGNLFGSSYKYAYASSTPLWYPHYDNSPSFSDFSSFGGWTSPSMKQYRGDVSVCSAGVDYNYKP
InterPro domains: - IPR002053: Glycoside hydrolase, family 25 (family) [13-211]
- IPR017853: Glycoside hydrolase superfamily (homologous_superfamily) [13-210]
- IPR051595: Glycosyl Hydrolase 25 Enzymes (family) [3-211]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0030246 (carbohydrate binding), GO:0016787 (hydrolase activity), GO:0030247 (polysaccharide binding), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:0009615 (response to virus), GO:0043207 (response to external biotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0005576 (extracellular region), GO:0043227 (membrane-bounded organelle), GO:0043230 (extracellular organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:1903561 (extracellular vesicle)
Protein: Ankyrin repeat domain 23 (D3ZVB9)
Organism: Rattus norvegicus (Rat)
Function: Not known
Sequence: MVSGERVGRKALEFGRGVPDPGGWPSGWTLGPQEAVAWEKLKLEEEKRKKLERFNSSRLTLDNLTDLENLIQRRRKKRQRHKVPPREPESGAEPQPQVPLEPVGLEMFLKAAAENQEALIDKYLADGGDPNAHDKLHRTALHWACLKGHRQLVNKLLAAGAAIETRDLLDRTPVFWACRGGHLDILKQLLNQGAQINAQDKIWSTPLHVAVRMGHSDCLEHLIECGAHINAQDKEGDTALHEAVRYGHHKATKLLLLYGAKLGMKNGASLTPVQLARDWQRGIREALQAHVGHPRTRC
InterPro domains: - IPR036770: Ankyrin repeat-containing domain superfamily (homologous_superfamily) [64-290]
- IPR002110: Ankyrin repeat (repeat) [111-267]
- IPR050663: Ankyrin Repeat and SOCS Box (family) [23-297]
Interaction partners: - Myopalladin
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0005488 (binding), GO:0005515 (protein binding), GO:0003712 (transcription coregulator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0009612 (response to mechanical stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030054 (cell junction), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043292 (contractile fiber), GO:0043229 (intracellular organelle), GO:0070161 (anchoring junction), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0030016 (myofibril), GO:0005911 (cell-cell junction), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0044291 (cell-cell contact zone), GO:0005634 (nucleus), GO:0014704 (intercalated disc)
Protein: Dikar, isoform B (Dikar, isoform E) (LD29048p) (Q9VRY3)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MVSTFIGLLDIQSWWEIPCISHFCSLFSSAFDLPDIDIEDLESALLSDGTSDEDQVALVPELIVRLLKGCDALQTVAKEITHSNYQMFLRRFLRQQCRLHQTENHFDTDIDFQSLPVRKRLHILHDLCHFRLDSVDVQVILSNLEADSLRVEPLGYDAKNSGYWYFYGTRLYREDKATGGSASSSSGSGSGGAGASTGGASNSKGIGSNGTVWQVICFTEEDWQNLAAKFKTSTNAKERELFNILDDNFLPKLPQLFRERERLRRRKLLQVRNSSRIRNIAELKARQEEERQRRERENLYQDRQNAHWLAPPQQQQQQQQQQQQQQQQSQQRTRRRLARQCS
InterPro domains: - IPR028938: Remodeling and spacing factor 1-like (family) [8-329]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0003008 (system process), GO:0007610 (behavior), GO:0007611 (learning or memory), GO:0050877 (nervous system process), GO:0007613 (memory), GO:0050890 (cognition), GO:0007616 (long-term memory)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098687 (chromosomal region), GO:0000785 (chromatin), GO:1902494 (catalytic complex), GO:0140513 (nuclear protein-containing complex), GO:0070603 (SWI/SNF superfamily-type complex), GO:0043229 (intracellular organelle), GO:1904949 (ATPase complex), GO:0043227 (membrane-bounded organelle), GO:0005705 (polytene chromosome interband), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031010 (ISWI-type complex), GO:0005694 (chromosome), GO:0005634 (nucleus), GO:0005700 (polytene chromosome)
Protein: Mitochondrial import receptor subunit tom40 (Protein MOM38) (Translocase of outer membrane 40 kDa subunit) (P24391)
Organism: Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Function: Channel-forming protein essential for import of protein precursors into mitochondria.
Subcellular location: Mitochondrion outer membrane; Multi-pass membrane protein.
Sequence: MASFSTESPLAMLRDNAIYSSLSDAFNAFQERRKQFGLSNPGTIETIAREVQRDTLLTNYMFSGLRADVTKAFSLAPLFQVSHQFAMGERLNPYAFAALYGTNQIFAQGNLDNEGALSTRFNYRWGDRTITKTQFSIGGGQDMAQFEHEHLGDDFSASLKAINPSFLDGGLTGIFVGDYLQAVTPRLGLGLQAVWQRQGLTQGPDTAISYFARYKAGDWVASAQLQAQGALNTSFWKKLTDRVQAGVDMTLSVAPSQSMMGGLTKEGITTFGAKYDFRMSTFRAQIDSKGKLSCLLEKRLGAAPVTLTFAADVDHVTQQAKLGMSVSIEASDVDLQEQQEGAQSLNIPF
InterPro domains: - IPR037930: Tom40 (family) [29-329]
- IPR005686: Mitochondrial import receptor subunit Tom40, fungi (family) [38-196]
- IPR023614: Porin domain superfamily (homologous_superfamily) [48-334]
- IPR027246: Eukaryotic porin/Tom40 (family) [40-323]
Interaction partners: - TOM7
- Mitochondrial import receptor subunit tom20
- Mitochondrial import receptor subunit tom22
- Mitochondrial import receptor subunit tom70
- Mitochondrial outer membrane beta-barrel protein Tob55
- Mitochondrial outer membrane protein porin
- Topogenesis of outer membrane beta barrel protein 37
- Mitochondrial distribution and morphology protein 10
- Mitochondrial outer membrane protein
- Mitochondrial import inner membrane translocase subunit tim50
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0009987 (cellular process), GO:0033036 (macromolecule localization), GO:0051641 (cellular localization), GO:0070727 (cellular macromolecule localization), GO:0008104 (protein localization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Monocarboxylate transporter 12 (MCT 12) (Solute carrier family 16 member 12) (Q8BGC3)
Organism: Mus musculus (Mouse)
Function: Functions as a transporter for creatine and as well for its precursor guanidinoacetate. Transport of creatine and GAA is independent of resting membrane potential and extracellular Na(+), Cl(-), or pH. Contributes to the process of creatine biosynthesis and distribution.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q6ZSM3}; Multi-pass membrane protein {ECO:0000255}. Basolateral cell membrane {ECO:0000269|PubMed:26376857}; Multi-pass membrane protein {ECO:0000255}. Note=Interaction with isoform 2 of BSG is required for its localization to the plasma membrane. {ECO:0000250|UniProtKB:Q6ZSM3}.
Sequence: MTKITRVSLASPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYSQTAWIHSIVDCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGFILGSFATSLKHLYLSLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDRSVPEKNHNRESQREDCKQASPYSPLTKECTETRLCCSLQQEYGFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHHQAAFLMSILGVIDIVGNITFGWLTDRRCLKNYRYVCYLFAVALDGLCYLCLPMLQTFPLLVPFSCTFGYFDGAYVTLIPVVTAEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFAMIFSSILLGFVRIVKRMKRTQVPFPVKDSDPKLQLWTNGSVAYSVARELDQKDEEPLPKARSGCNLT
InterPro domains: - IPR050327: Proton-linked Monocarboxylate Transporter (family) [13-434]
- IPR036259: MFS transporter superfamily (homologous_superfamily) [11-439]
- IPR020846: Major facilitator superfamily domain (domain) [17-435]
- IPR011701: Major facilitator superfamily (family) [26-327]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity), GO:0005342 (organic acid transmembrane transporter activity), GO:0072349 (modified amino acid transmembrane transporter activity), GO:0046943 (carboxylic acid transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0006082 (organic acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0032787 (monocarboxylic acid metabolic process), GO:0006090 (pyruvate metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0045178 (basal part of cell), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0009925 (basal plasma membrane), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0016323 (basolateral plasma membrane)
Protein: procollagen-proline 4-dioxygenase (EC 1.14.11.2) (Q9I7H5)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Endoplasmic reticulum lumen {ECO:0000256|ARBA:ARBA00004319}.
Sequence: MLDRHCLYIGIFQLIIWVGVANGEFYSSVDSMQDLAQVEEELLNATRSYVESQQKQLDFYRRYVEQIKREHEWATSQLKLDDYLGHPLHAFRLIKRLVRDWDSLIFEPILANNAREEFRAFVEVLSRDLGYPDQSELQGAIKGLARLQKVYNLATSDLADGIIGGLNYGSDLRWRECYEIGVQLFDLGEYQRSLEWLQVAFILLRNSPREEKDADHYLSDIREYASMANFELGNPKKAARLLSQILESQPTHSAQQTQKYLESRVPGKNVQETKPSWFSNYTRLCQGRRLPEERSGDPLRCYLDGKRHAYFTLAPLQVEPVHLDPDINVYHGMLSSKQILSIFEEADKEEMVRSAVAGSGGEGTVRDLRVSQQTWLDYKSPVMNSVGRIIQFVSGFDMAGAEHMQVANYGVGGQYEPHPDYFEVNLPKNFEGDRISTSMFYLSDVEQGGYTVFTKLNVFLPPVKGALVMWHNLHRSLHVDARTLHAGCPVIVGSKRIGNIWMHSGYQEFRRPCNLTSDSYKSLAYRD
InterPro domains: - IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [135-265]
- IPR013547: Prolyl 4-hydroxylase alpha-subunit, N-terminal (domain) [28-164]
- IPR045054: Prolyl 4-hydroxylase (family) [139-510]
- IPR005123: Oxoglutarate/iron-dependent dioxygenase domain (domain) [400-504]
- IPR044862: Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain (domain) [404-503]
- IPR006620: Prolyl 4-hydroxylase, alpha subunit (domain) [325-503]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016491 (oxidoreductase activity), GO:0051213 (dioxygenase activity), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen), GO:0031543 (peptidyl-proline dioxygenase activity), GO:0016706 (2-oxoglutarate-dependent dioxygenase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009887 (animal organ morphogenesis), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048732 (gland development), GO:0035272 (exocrine system development), GO:0022612 (gland morphogenesis), GO:0007435 (salivary gland morphogenesis), GO:0007431 (salivary gland development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: ABHD16B (EC 3.1.1.111) (Alpha/beta hydrolase domain-containing protein 16B) (Abhydrolase domain-containing protein 16B) (Q9H3Z7)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MCVICFVKALVRVFKIYLTASYTYPFRGWPVAFRWDDVRAVGRSSSHRALTCAAAAAGVWLLRDETLGGDALGRPPRGARSQAQCLLQQLRELPGQLASYALAHSLGRWLVYPGSVSLMTRALLPLLQQGQERLVERYHGRRAKLVACDGNEIDTMFMDRRQHPGSHVHGPRLVICCEGNAGFYEMGCLSAPLEAGYSVLGWNHPGFGSSTGVPFPQHDANAMDVVVEYALHRLHFPPAHLVVYGWSVGGFTATWATMTYPELGALVLDATFDDLVPLALKVMPHSWKGLVVRTVREHFNLNVAEQLCCYPGPVLLLRRTQDDVVSTSGRLRPLSPGDVEGNRGNELLLRLLEHRYPVVMAREGRAVVTRWLRAGSLAQEAAFYARYRVDEDWCLALLRSYRARCEEELEGEEALGPHGPAFPWLVGQGLSSRRRRRLALFLARKHLKNVEATHFSPLEPEEFQLPWRL
InterPro domains: - IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [141-332]
- IPR000073: Alpha/beta hydrolase fold-1 (domain) [173-305]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0008233 (peptidase activity), GO:0017171 (serine hydrolase activity), GO:0019899 (enzyme binding), GO:0016298 (lipase activity), GO:0008236 (serine-type peptidase activity), GO:0004175 (endopeptidase activity), GO:0002020 (protease binding), GO:0004252 (serine-type endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0006629 (lipid metabolic process), GO:1901575 (organic substance catabolic process), GO:0044248 (cellular catabolic process), GO:0006638 (neutral lipid metabolic process), GO:1901568 (fatty acid derivative metabolic process), GO:0046486 (glycerolipid metabolic process), GO:0044242 (cellular lipid catabolic process), GO:0016042 (lipid catabolic process), GO:0046461 (neutral lipid catabolic process), GO:1901569 (fatty acid derivative catabolic process), GO:0006639 (acylglycerol metabolic process), GO:0046503 (glycerolipid catabolic process), GO:0046464 (acylglycerol catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Ribosomal RNA small subunit methyltransferase G (EC 2.1.1.-) (16S rRNA 7-methylguanosine methyltransferase) (16S rRNA m7G methyltransferase) (Q97QD4)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Function: Specifically methylates the N7 position of a guanine in 16S rRNA.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00074}.
Sequence: MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAITDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDSLNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELTIPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKKKETPNKYPRKAGMPNKRPL
InterPro domains: - IPR029063: S-adenosyl-L-methionine-dependent methyltransferase superfamily (homologous_superfamily) [1-237]
- IPR003682: rRNA small subunit methyltransferase G (family) [2-237]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0032259 (methylation), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0043414 (macromolecule methylation), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0043412 (macromolecule modification), GO:0090304 (nucleic acid metabolic process), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0001510 (RNA methylation), GO:0010467 (gene expression), GO:0042254 (ribosome biogenesis), GO:0016070 (RNA metabolic process), GO:0031167 (rRNA methylation), GO:0006396 (RNA processing), GO:0009451 (RNA modification), GO:0034470 (ncRNA processing), GO:0000154 (rRNA modification), GO:0006364 (rRNA processing), GO:0034660 (ncRNA metabolic process), GO:0016072 (rRNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Paired-type homeobox protein (O96616)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Sequence: MQVSGWSSVLNLSMDAPNPEISPNSVTNSSSVYMIRQMALIQQARVAAAAVAMQQQQQQQQQQQRDLNRELGMDPHSEQRIKLDSVSPTHNIHAGSSRGIKQDPLSDEGADSNLGQNDCTESSKKRRGRTNFNSWQLRELERVFQGSHYPDIFMREALATKLDLMEGRIAVWFQNRRAKWRKQEHTKKGPGRPAHNAHPQSCSGDPIPLSELRARELAQRSKRMKKAIDRQAKKLQDKGLEVDYARLEAEYLAVHQENGVDENNWLDDDGYDDLHIDVVGVEPEYVTGDSLDHSFCSSRTYQTKSTSSELDSNDMGLQGRVETPPPPQPPMQNKTLYNSPFSIESLLGS
InterPro domains: - IPR001356: Homeodomain (domain) [123-187]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [110-184]
- IPR017970: Homeobox, conserved site (conserved_site) [158-181]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific)
Biological Process (BP): GO:0008150 (biological process), GO:0000003 (reproduction), GO:0019953 (sexual reproduction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Calcineurin-like phosphoesterase domain-containing protein (O33337)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Function: Not known
Sequence: MTWKGSGQETVGAEPTLWAISDLHTGHLGNKPVAESLYPSSPDDWLIVAGDVAERTDEIRWSLDLLRRRFAKVIWVPGNHELWTTNRDPMQIFGRARYDYLVNMCDEMGVVTPEHPFPVWTERGGPATIVPMFLLYDYSFLPEGANSKAEGVAIAKERNVVATDEFLLSPEPYPTRDAWCHERVAATRARLEQLDWMQPTVLVNHFPLLRQPCDALFYPEFSLWCGTTKTADWHTRYNAVCSVYGHLHIPRTTWYDGVRFEEVSVGYPREWRRRKPYSWLRQVLPDPQYAPGYLNDFGGHFVITPEMRTQAAQFRERLRQRQSR
InterPro domains: - IPR004843: Calcineurin-like, phosphoesterase domain (domain) [16-250]
- IPR052963: Phosphopantetheine Phosphodiesterase (family) [13-321]
- IPR029052: Metallo-dependent phosphatase-like (homologous_superfamily) [14-281]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006520 (amino acid metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044282 (small molecule catabolic process), GO:1901575 (organic substance catabolic process), GO:0006082 (organic acid metabolic process), GO:0044248 (cellular catabolic process), GO:0016054 (organic acid catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0043436 (oxoacid metabolic process), GO:1901605 (alpha-amino acid metabolic process), GO:0009063 (amino acid catabolic process), GO:0019752 (carboxylic acid metabolic process), GO:1901606 (alpha-amino acid catabolic process), GO:0046395 (carboxylic acid catabolic process), GO:0046416 (D-amino acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)