Protein: Mitochondrial ribonuclease P catalytic subunit (EC 3.1.26.5) (Mitochondrial ribonuclease P protein 3) (Mitochondrial RNase P protein 3) (Protein mulder) (Protein only RNase P catalytic subunit) (Q9W413)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Mitochondrion {ECO:0000269|PubMed:27131785}.
Sequence: MYNLRLLRNLLPIAGHAHPRWLASQHKRRPQPGSLPADRLDQLRSDLFERRHELSGAEWTEVRRSLVDGYKHINGHNVDAVILGVCSAPNQLSLAKSYVEFLRSRGSKPNAATLGRLLRVYNAAYHERPLSEAEQSEILQICRSLQAEHETLDASSCENVIHGLVATSGDDWQRGLPLLEMMKVTSTPSVAAYSALAEKAFSVATPEQELAWRLLEEMATARKPPKCEVYLALLNRLANETAQLPAQLSLLLQFLERHEILVSQRVAIRLQELSSQVPQLLHTRTTHLGGLGKCQSCQQHLQPVAISDEEFRQLSECFLERVLIRRDVFQRSTPEEVARFKKFVEKTAPYDCVIDGLNVAYSTGTKKTPQQLAKLVATVVRHFREQDKRVLVLGREHMRNWSKQAMHYVHCNASLFLTSNLSHDDPFLLYATLRSGQETDFFSRDLMRSHAFHLGTELKPIFRRWQQEHQFSLVTQTQTGQIIVKEPVRHRLCAHQVADTWHVPYCAQYTPHPTDSFEVPANWLCIQMKEQTIPATKTKTKTTR
InterPro domains: - IPR033495: Mitochondrial ribonuclease P catalytic subunit, PIN domain (domain) [352-473]
- IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [80-311]
- IPR031595: Protein-only RNase P, C-terminal (domain) [291-525]
Interaction partners: - 3-hydroxyacyl-CoA dehydrogenase type-2
- Mitochondrial ribonuclease P protein 1 homolog
- Ribonuclease P/MRP protein subunit POP5
- Ribonuclease P/MRP subunit p21, isoform A
- FI18256p1
- NADH dehydrogenase complex I, assembly factor 6 homolog
- LD06392p
- Endoribonuclease Dcr-2
- Ribonuclease 3
- Transcription initiation factor TFIID subunit 11
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016787 (hydrolase activity), GO:0140098 (catalytic activity, acting on RNA), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0004518 (nuclease activity), GO:0140101 (catalytic activity, acting on a tRNA), GO:0004540 (ribonuclease activity), GO:0004549 (tRNA-specific ribonuclease activity), GO:0004519 (endonuclease activity), GO:0004521 (RNA endonuclease activity), GO:0004526 (ribonuclease P activity), GO:0016891 (RNA endonuclease activity, producing 5'-phosphomonoesters), GO:0016893 (endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0140053 (mitochondrial gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0000963 (mitochondrial RNA processing), GO:0034470 (ncRNA processing), GO:0000966 (RNA 5'-end processing), GO:0000959 (mitochondrial RNA metabolic process), GO:0034660 (ncRNA metabolic process), GO:0090646 (mitochondrial tRNA processing), GO:0099116 (tRNA 5'-end processing), GO:0006399 (tRNA metabolic process), GO:0008033 (tRNA processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098798 (mitochondrial protein-containing complex), GO:1902494 (catalytic complex), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0140535 (intracellular protein-containing complex), GO:0030677 (ribonuclease P complex), GO:0005739 (mitochondrion), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:1905348 (endonuclease complex), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005759 (mitochondrial matrix), GO:0070013 (intracellular organelle lumen), GO:1902555 (endoribonuclease complex)