Protein: Transmembrane 9 superfamily member (A2AFI6)
Organism: Mus musculus (Mouse)
Subcellular location: Membrane; Multi- pass membrane protein
Sequence: MVVPEAGFKMGLSGRRVETKLCPGLHGLKWWLLLCFLATTCDAFFFPGLVPVTYCEEGHPNSYCKSSIQVYADKLYSVDSVMFYDYDSFDFCQDSLKRTPSETLGQILFGEQVTSCPYKFSFNKDETCRKVCVKSYAPDNEDDMNKLAFLKKGIKQDYRHHWIVDNTGIIWCYDTENEEHHCMSGFPIGCFNAPSDQVKGSCLINPEFNKNNSLYLFNHLDITITYHIESDTTVKVAKLISSRVDPKSYKHLDEDHLTCNEPPMEIPEEDTENLNVIYTYSVKFEESKATEWSSEGDYDLDSTAETSLQWIRLVNSFFVVLFLCGLVVILLLRSIWRDIAKFNRIKISVYDRRLFGWRLIHGNLFRLPEHGMLLSILLGQGTQVFIMTFLSLFLAGLGFLTPADQNVLVNYGVVLWLALEIPAGYMSAKMYKTFKGINWKMHFLLTTVLFPGIVFADIFIMNLILWMDGSPAAISFCTLASLFALYFGVSTPLTFLGVYFGKREKFEFPVYAPKHEHGSPQRTFFPKSTITIILGSLLPFGCIFLQLSYILNRIWSPHMYYLFAFLLLLFLIFMISCSEVTVLLCYFRLCAEDRGWWWRAFLTSSFTSAYIFIYVIHYFFTKLQVTSIGSTFMYFGYAFILVLAFFLFTGTIGFFSCFFFVTTIYGVIKED
InterPro domains: - IPR004240: Nonaspanin (TM9SF) (family) [55-670]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0042592 (homeostatic process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0051641 (cellular localization), GO:0048869 (cellular developmental process), GO:0009628 (response to abiotic stimulus), GO:0009058 (biosynthetic process), GO:0019222 (regulation of metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0051234 (establishment of localization), GO:0071704 (organic substance metabolic process), GO:0048871 (multicellular organismal-level homeostasis), GO:0033036 (macromolecule localization), GO:0007267 (cell-cell signaling), GO:0048878 (chemical homeostasis), GO:0065008 (regulation of biological quality), GO:0044237 (cellular metabolic process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0044238 (primary metabolic process), GO:0048522 (positive regulation of cellular process), GO:0050801 (monoatomic ion homeostasis), GO:1901576 (organic substance biosynthetic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0030154 (cell differentiation), GO:0046483 (heterocycle metabolic process), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0060255 (regulation of macromolecule metabolic process), GO:0044249 (cellular biosynthetic process), GO:0098771 (inorganic ion homeostasis), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0060249 (anatomical structure homeostasis), GO:0045184 (establishment of protein localization), GO:0035295 (tube development), GO:1901360 (organic cyclic compound metabolic process), GO:0050878 (regulation of body fluid levels), GO:0042127 (regulation of cell population proliferation), GO:0006139 (nucleobase-containing compound metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0033554 (cellular response to stress), GO:0006810 (transport), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0070727 (cellular macromolecule localization), GO:0031323 (regulation of cellular metabolic process), GO:0007166 (cell surface receptor signaling pathway), GO:0080090 (regulation of primary metabolic process), GO:0008284 (positive regulation of cell population proliferation), GO:0009059 (macromolecule biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0071705 (nitrogen compound transport), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0055123 (digestive system development), GO:0051246 (regulation of protein metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0097696 (receptor signaling pathway via STAT), GO:0071702 (organic substance transport), GO:0050891 (multicellular organismal-level water homeostasis), GO:0050678 (regulation of epithelial cell proliferation), GO:0010468 (regulation of gene expression), GO:0055074 (calcium ion homeostasis), GO:0050679 (positive regulation of epithelial cell proliferation), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0055080 (monoatomic cation homeostasis), GO:0048514 (blood vessel morphogenesis), GO:0090304 (nucleic acid metabolic process), GO:0015031 (protein transport), GO:0031326 (regulation of cellular biosynthetic process), GO:0051247 (positive regulation of protein metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0008104 (protein localization), GO:0051252 (regulation of RNA metabolic process), GO:0048565 (digestive tract development), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0072657 (protein localization to membrane), GO:0016070 (RNA metabolic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0030003 (intracellular monoatomic cation homeostasis), GO:0042886 (amide transport), GO:0015833 (peptide transport), GO:0002790 (peptide secretion), GO:0071692 (protein localization to extracellular region), GO:1902680 (positive regulation of RNA biosynthetic process), GO:0030073 (insulin secretion), GO:0032774 (RNA biosynthetic process), GO:0097659 (nucleic acid-templated transcription), GO:0030072 (peptide hormone secretion), GO:0006357 (regulation of transcription by RNA polymerase II), GO:0045893 (positive regulation of DNA-templated transcription), GO:0016071 (mRNA metabolic process), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0006351 (DNA-templated transcription), GO:0045944 (positive regulation of transcription by RNA polymerase II), GO:0009299 (mRNA transcription), GO:0006366 (transcription by RNA polymerase II), GO:0042789 (mRNA transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)