Protein: Serotonin N-acetyltransferase (Serotonin acetylase) (EC 2.3.1.87) (Aralkylamine N-acetyltransferase) (AA-NAT) (P79774)
Organism: Gallus gallus (Chicken)
Function: Catalyzes the N-acetylation of serotonin into N-acetylserotonin.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q16613}.
Sequence: MPVLGAVPFLKPTPLQGPRNSPGRQRRHTLPASEFRCLSPEDAVSVFEIEREAFISVSGDCPLHLDEIRHFLTLCPELSLGWFEEGRLVAFIIGSLWDQDRLSQAALTLHNPRGTAVHIHVLAVHRTFRQQGKGSILMWRYLQYLRCLPCARRAVLMCEDFLVPFYEKCGFVAVGPCQVTVGTLAFTEMQHEVRGHAFMRRNSGC
InterPro domains: - IPR016181: Acyl-CoA N-acyltransferase (homologous_superfamily) [30-178]
- IPR051635: Serotonin N-acetyltransferase-like (family) [15-205]
- IPR000182: GNAT domain (domain) [33-194]
Interaction partners: - Acetylserotonin O-methyltransferase
- Aromatic-L-amino-acid decarboxylase
- Amine oxidase.
- Amine oxidase
- Uncharacterized protein.
- Basic helix-loop-helix ARNT-like protein 1
- Establishment of sister chromatid cohesion N-acetyltransferase 1.
- Establishment of sister chromatid cohesion N-acetyltransferase 2.
- DNA-directed RNA polymerase subunit
- G_PROTEIN_RECEP_F1_2 domain-containing protein.
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016410 (N-acyltransferase activity), GO:0016407 (acetyltransferase activity), GO:0008080 (N-acetyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0048511 (rhythmic process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0042221 (response to chemical), GO:0006807 (nitrogen compound metabolic process), GO:0007623 (circadian rhythm), GO:0042445 (hormone metabolic process), GO:0071704 (organic substance metabolic process), GO:0065008 (regulation of biological quality), GO:0044237 (cellular metabolic process), GO:0009719 (response to endogenous stimulus), GO:0051716 (cellular response to stimulus), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0046483 (heterocycle metabolic process), GO:0019538 (protein metabolic process), GO:0071495 (cellular response to endogenous stimulus), GO:0044249 (cellular biosynthetic process), GO:1901700 (response to oxygen-containing compound), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0010817 (regulation of hormone levels), GO:0043170 (macromolecule metabolic process), GO:0010033 (response to organic substance), GO:0042446 (hormone biosynthetic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901698 (response to nitrogen compound), GO:0070887 (cellular response to chemical stimulus), GO:0043603 (amide metabolic process), GO:0071417 (cellular response to organonitrogen compound), GO:0046683 (response to organophosphorus), GO:1901362 (organic cyclic compound biosynthetic process), GO:0071310 (cellular response to organic substance), GO:0019438 (aromatic compound biosynthetic process), GO:0042430 (indole-containing compound metabolic process), GO:1901699 (cellular response to nitrogen compound), GO:0051604 (protein maturation), GO:0009308 (amine metabolic process), GO:0043604 (amide biosynthetic process), GO:0036211 (protein modification process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0051591 (response to cAMP), GO:0043412 (macromolecule modification), GO:0010243 (response to organonitrogen compound), GO:0018130 (heterocycle biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0014070 (response to organic cyclic compound), GO:1901701 (cellular response to oxygen-containing compound), GO:0010467 (gene expression), GO:0006474 (N-terminal protein amino acid acetylation), GO:0006576 (biogenic amine metabolic process), GO:0031365 (N-terminal protein amino acid modification), GO:0071320 (cellular response to cAMP), GO:0043543 (protein acylation), GO:0071407 (cellular response to organic cyclic compound), GO:0042435 (indole-containing compound biosynthetic process), GO:0006586 (indolalkylamine metabolic process), GO:0009309 (amine biosynthetic process), GO:0014074 (response to purine-containing compound), GO:0042401 (biogenic amine biosynthetic process), GO:0046219 (indolalkylamine biosynthetic process), GO:0006473 (protein acetylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)