Protein: SET domain-containing protein (Q38BE1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MQTEALQHRMSKADLVAVFCDKGCETAMTAQLIPLARFPFKLFPVCNGPSMYRAVREIYASRNLYRCALNLCTGTAEDEELASPQVLSSLFEHFDILYGGCRYATLRQPLDVLFMMAFYAGLPLPRSTVVKADTQTDYLELRLPVKLRNANPLQSRFETVVEKKSALLRMVRQGIQSHGKLIAWEVSPVKDMGLEVLVWGAGSFAVATEPPRQQDDAFIKKWKPSIEKWAAAFSKDVLNRSGFARLRFNSSTTSEKLVLEDIDVGCSLLGLCTQLSIVASQEGLLDECVRECERAPLAPVAEVCFGGENKGYYLRASRDVPKGGLVFEDEERSFSIVTRPFVEKTWDEEKKKLFREYAWPIDADGHVYVTWDSDPNCWRPINHSCEPNCIFDENHSLNVIAARDIAKGDELTMDYCTFCDNTMKPFSCFCGSAYCREIIVPNEESLRAYGTHAWHRKVPAPHLNDL
InterPro domains: - IPR046341: SET domain superfamily (homologous_superfamily) [254-447]
- IPR001214: SET domain (domain) [299-422]
- IPR003616: Post-SET domain (domain) [424-440]
- IPR053201: Flavunoidine biosynthesis N-methyltransferase (family) [10-459]
Interaction partners: - Histone H2A
- Histone H3, putative
- Histone H3 variant
- Histone H4
- Histone H4
- Histone H2B
- Histone H2B
- Histone H2B
- Histone H2B
- Trypanothione synthetase, putative
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0008276 (protein methyltransferase activity), GO:0016279 (protein-lysine N-methyltransferase activity), GO:0042054 (histone methyltransferase activity), GO:0008168 (methyltransferase activity), GO:0018024 (histone lysine N-methyltransferase activity), GO:0008757 (S-adenosylmethionine-dependent methyltransferase activity), GO:0008170 (N-methyltransferase activity), GO:0016278 (lysine N-methyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0043412 (macromolecule modification), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0009451 (RNA modification), GO:0006400 (tRNA modification), GO:0034470 (ncRNA processing), GO:0034660 (ncRNA metabolic process), GO:0002097 (tRNA wobble base modification), GO:0034227 (tRNA thio-modification), GO:0006399 (tRNA metabolic process), GO:0008033 (tRNA processing), GO:0002098 (tRNA wobble uridine modification)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)