Protein: Sodium-dependent phosphate transporter 1-A (Q6NV12)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport
Subcellular location: Membrane; Multi-pass membrane protein
Sequence: MESTTLASLAAVSVLAAGAQTDMSDVLWLLILGFVIAFILAFSVGANDVANSFGTAVGSGVVTLRQACILATIFETVGAMLLGAKVSETIRSGIIDVHMYNGSEAVLMAGSISAMFGSAVWQLAASFLKLPISGTHCIVGATIGFSMVARGHQGVKWLELLRIVASWFLSPLLSGIMSAVLFYFVRKFILNKDDPVPNGLRALPVFYAVTMGINLFSIMFTGAPMLGFDRIPWWGTLLISLGCAILTALVVWFIVCPRLKKKMQSKCLGPNIADTSGTQLVEKKPSSNGLMDHHPGPPRNYSPVPQTPPADSNKVAFDIGGSAETDLDKKEFDTKDQDCTHALNGSGGIVIPDLSGNQFHTVHKDSGIYKDLLHKLHLAKVGECIGEPVEKPIRRNNSYTSYTMAIYGIHGSLKDGEGGSRTGLDGEKRRSRYDSYNSYCTAVADGEAALEDAALAVGMEDEALREDVLEEDIDELEIDKPEVSTLFQFLQILTACFGSFAHGGNDVSNAIGPLVALWLIYDSASVAPSAPTPIWLLLYGGVGICTGLWIWGRRVIQTMGKDLTPITPSSGFSIELASAITVVVASNIGLPVSTTHCKVGSVVSVGWLRSRKAVDWHLFRNIFIAWFVTVPISGLISAAIMALFYYVILPLT
InterPro domains: - IPR001204: Phosphate transporter (family) [24-648]
Interaction partners: - Solute carrier family 12 member 3
- Solute carrier family 13 (Sodium/sulphate symporters), member 1
- Ciliary microtubule associated protein 1B
- Slow myosin heavy chain 1
- Paired box protein Pax-2a
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0022853 (active monoatomic ion transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0015081 (sodium ion transmembrane transporter activity), GO:0015291 (secondary active transmembrane transporter activity), GO:0015293 (symporter activity), GO:0015294 (solute:monoatomic cation symporter activity), GO:0046873 (metal ion transmembrane transporter activity), GO:0015370 (solute:sodium symporter activity), GO:0005436 (sodium:phosphate symporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0051716 (cellular response to stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0006950 (response to stress), GO:0032989 (cellular component morphogenesis), GO:0000902 (cell morphogenesis), GO:0009611 (response to wounding), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0033554 (cellular response to stress), GO:0048731 (system development), GO:0016043 (cellular component organization), GO:0031099 (regeneration), GO:0022008 (neurogenesis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0032990 (cell part morphogenesis), GO:0031102 (neuron projection regeneration), GO:0048858 (cell projection morphogenesis), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0048678 (response to axon injury), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0031103 (axon regeneration), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0048812 (neuron projection morphogenesis), GO:0061564 (axon development), GO:0007409 (axonogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)