Protein: Kv channel interacting protein 3, calsenilin (A2AHT3)
Organism: Mus musculus (Mouse)
Function: Not known
Sequence: MRQLPAGPSSLACSGCKAGRLVTVPFSSRDAEDQGSREGIRWQPPGRSWAHTTEQEGKHQVAKATVHPPGPDALLLNQVDPVQCCPTRLSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQLFENVI
InterPro domains: - IPR011992: EF-hand domain pair (homologous_superfamily) [103-280]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [203-263]
- IPR002048: EF-hand domain (domain) [154-273]
- IPR028846: Recoverin family (family) [97-275]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0140677 (molecular function activator activity), GO:1901363 (heterocyclic compound binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0016247 (channel regulator activity), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0048306 (calcium-dependent protein binding), GO:0099106 (ion channel regulator activity), GO:0043169 (cation binding), GO:0015459 (potassium channel regulator activity), GO:0046872 (metal ion binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003677 (DNA binding), GO:0003690 (double-stranded DNA binding), GO:0000287 (magnesium ion binding), GO:0043565 (sequence-specific DNA binding), GO:0005509 (calcium ion binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding), GO:0001046 (core promoter sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0051641 (cellular localization), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0032879 (regulation of localization), GO:0051234 (establishment of localization), GO:0003008 (system process), GO:0033036 (macromolecule localization), GO:0009892 (negative regulation of metabolic process), GO:0033555 (multicellular organismal response to stress), GO:0050794 (regulation of cellular process), GO:0006950 (response to stress), GO:0048523 (negative regulation of cellular process), GO:0007610 (behavior), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0051049 (regulation of transport), GO:0034762 (regulation of transmembrane transport), GO:0060255 (regulation of macromolecule metabolic process), GO:0051668 (localization within membrane), GO:0031324 (negative regulation of cellular metabolic process), GO:0048266 (behavioral response to pain), GO:0010035 (response to inorganic substance), GO:0010941 (regulation of cell death), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0048265 (response to pain), GO:0006810 (transport), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0070727 (cellular macromolecule localization), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0050877 (nervous system process), GO:0080090 (regulation of primary metabolic process), GO:0010038 (response to metal ion), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0043067 (regulation of programmed cell death), GO:0034765 (regulation of monoatomic ion transmembrane transport), GO:1901214 (regulation of neuron death), GO:0006811 (monoatomic ion transport), GO:0007600 (sensory perception), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0051252 (regulation of RNA metabolic process), GO:0008104 (protein localization), GO:0043269 (regulation of monoatomic ion transport), GO:0051253 (negative regulation of RNA metabolic process), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:0072657 (protein localization to membrane), GO:0042981 (regulation of apoptotic process), GO:0006812 (monoatomic cation transport), GO:0032026 (response to magnesium ion), GO:2001141 (regulation of RNA biosynthetic process), GO:1990778 (protein localization to cell periphery), GO:0006355 (regulation of DNA-templated transcription), GO:0043523 (regulation of neuron apoptotic process), GO:0010959 (regulation of metal ion transport), GO:0019233 (sensory perception of pain), GO:0072659 (protein localization to plasma membrane), GO:1904062 (regulation of monoatomic cation transmembrane transport), GO:1902679 (negative regulation of RNA biosynthetic process), GO:0006357 (regulation of transcription by RNA polymerase II), GO:1901379 (regulation of potassium ion transmembrane transport), GO:0045892 (negative regulation of DNA-templated transcription), GO:1903507 (negative regulation of nucleic acid-templated transcription), GO:0043266 (regulation of potassium ion transport), GO:0030001 (metal ion transport), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0000122 (negative regulation of transcription by RNA polymerase II), GO:0006813 (potassium ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:1990351 (transporter complex), GO:0098797 (plasma membrane protein complex), GO:1902495 (transmembrane transporter complex), GO:0005886 (plasma membrane), GO:0034702 (ion channel complex), GO:0008076 (voltage-gated potassium channel complex), GO:0034703 (cation channel complex), GO:0034705 (potassium channel complex)