wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Phycocyanobilin lyase subunit CpcS (EC 4.-.-.-) (A8HTM2)
Organism: Picosynechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum)
Function: Attaches a phycocyanobilin (PCB) chromophore to 'Cys-82' of the C-phycocyanain beta subunit (PhcB) and the unique PCB that is attached to allophycocyanin alpha and beta subunits (ApcA and ApcB). In vitro, and probably also in vivo, chromophorylates ApcD and ApcF.
Sequence: MQSFADAKEFFQYSAGQWQSRRVTHHLPFRRAESGGSNIQVETLEKDDPRIIEICQMHDMDASLSVGGSYVTWAGTMQWDKDDENHEGSTVFALIPDADNPRQGKLLRERGYAEIVPVAGEYHLDHEDGLVLTTEYETMTIYERFWFANPDLRLRTSTVKRFGGFNTTTFCMEERIQTSPVTATAAAETNPLYAISGW
InterPro domains: - IPR012674: Calycin (homologous_superfamily) [4-190]
- IPR018536: Chromophore lyase CpcS/CpeS (family) [5-176]
Interaction partners: - Phycocyanobilin lyase CpcT
- C-phycocyanin subunit beta
- Phycocyanobilin lyase subunit alpha
- C-phycocyanin subunit alpha
- Allophycocyanin alpha subunit
- Allophycocyanin beta subunit
- Phycocyanobilin lyase subunit beta
- Allophycocyanin subunit beta-18
- Allophycocyanin subunit alpha-B
- Phycobilisome rod-core linker polypeptide CpcG
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: 4-alpha-glucanotransferase (EC 2.4.1.25) (Amylomaltase) (Disproportionating enzyme) (Q8DT30)
Organism: Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
Function: Not known
Sequence: MEKRASGILMHISSLPGKFGIGTFGQEAYDFVDFLKKTGQTYWQLLPLTTTSYGDSPYQSFSAVAGNVNFIDFKKLQEAGLLDEDDYNSVSFGEDEEIVDYALLFKVRRPILEKAVINFLADKTNLKKLALFEEKNETWLDDYAEFMAIKEHFGNKSLQEWGDKKAIRRDEERLVRYRHLLADEISYHKVTQYFFFEQWLALKAYANKNKIKIIGDMPIYVAKDSVEVWTMPELFKMDDDLQPLSVAGCPPDEFSDEGQLWGNPIYDWKKHRETGFAWWIYRIQESFKIYDILRIDHFKGFSDYWEIKGNSKTAKNGSWHPGPGIALFRAVQNVLGDMPIIAEDLGYVDDRARQLLKETGFPGMKILEFGFYDLSGRSVDIPHHYVQNSVAYIGTHDNDVVNGWYDRLTVEQEEFVDAYTNRKPIEPVNQAMLRLLFSTVSNTAILTMQDLLNKPASSRMNTPSTIGGNWQWRMRAKDLTQDKINFLSKLTKLYQRGNEENDTKNKTIQ
InterPro domains: - IPR017853: Glycoside hydrolase superfamily (homologous_superfamily) [3-496]
- IPR003385: Glycoside hydrolase, family 77 (family) [2-499]
Interaction partners: - Alpha-1,4 glucan phosphorylase
- Alpha-1,4 glucan phosphorylase
- Endonuclease/exonuclease/phosphatase domain-containing protein
- Pullulanase
- Glycogen synthase
- 1,4-alpha-glucan branching enzyme GlgB
- Phosphoglucomutase
- Sucrose phosphorylase
- Intracellular alpha-amylase
- Glycogen biosynthesis protein GlgD
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0044248 (cellular catabolic process), GO:0005975 (carbohydrate metabolic process), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0006091 (generation of precursor metabolites and energy), GO:0044262 (cellular carbohydrate metabolic process), GO:0044275 (cellular carbohydrate catabolic process), GO:0009057 (macromolecule catabolic process), GO:0009311 (oligosaccharide metabolic process), GO:0044264 (cellular polysaccharide metabolic process), GO:0005976 (polysaccharide metabolic process), GO:0015980 (energy derivation by oxidation of organic compounds), GO:0016052 (carbohydrate catabolic process), GO:0005984 (disaccharide metabolic process), GO:0000272 (polysaccharide catabolic process), GO:0044042 (glucan metabolic process), GO:0006112 (energy reserve metabolic process), GO:0044247 (cellular polysaccharide catabolic process), GO:0006073 (cellular glucan metabolic process), GO:0005977 (glycogen metabolic process), GO:0005980 (glycogen catabolic process), GO:0009251 (glucan catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Protein E6 (Q1AHS5)
Organism: human papillomavirus 97
Function: Not known
Subcellular location: Host cytoplasm {ECO:0000256|HAMAP-Rule:MF_04006, ECO:0000256|RuleBase:RU363123}. Host nucleus {ECO:0000256|HAMAP-Rule:MF_04006, ECO:0000256|RuleBase:RU363123}.
Sequence: MARFEDPSKRPYKLPDLCTELNTSLPEIEISCVYCKTTLERTEVYEFAFKDLFVVYRDCIAYAACTKCLTFFSKIRELRYYSHSVYGDTLEKITNTGLYNLLIRCLQCQKPLNPADKYKHLKDKRRFHHISGYYRGQCNSCYNQSRQERLSRRRETQV
InterPro domains: - IPR001334: E6 early regulatory protein (family) [7-144]
- IPR038575: E6 superfamily (homologous_superfamily) [1-158]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0046914 (transition metal ion binding), GO:0008270 (zinc ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0048523 (negative regulation of cellular process), GO:0009892 (negative regulation of metabolic process), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0051252 (regulation of RNA metabolic process), GO:0051253 (negative regulation of RNA metabolic process), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:0010468 (regulation of gene expression), GO:2001141 (regulation of RNA biosynthetic process), GO:1902679 (negative regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903507 (negative regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045892 (negative regulation of DNA-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0043657 (host cell), GO:0033643 (host cell part), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0033647 (host intracellular organelle), GO:0033648 (host intracellular membrane-bounded organelle), GO:0042025 (host cell nucleus)
Protein: Transcription factor Jun (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (Q2L4Q5)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Function: Not known
Sequence: MSTKMETTFYDDSHNAFSQHQNAGYGYNPKALKHSMTLNLADPTITLKPHLQAKASDILTSPDVQLLKLASPELERLIIQSSNGLITTTPTPTQFLCPRNVTDEQEGFAEGFVRALAELHHQHVLPNAPGVPVTSTGQTRINNSTTLPPVCSVAGSTVYNNVAMRSESPVYENLNTFTPAVTTNSAPGYTTSVPTMSFPSAPPQLPIYGQQSHPHPRLTALKEEPQTVPEMLGETPPLSPIDMENQERIKAERKRMRNRVAASKCRKRKLERISRLEDKVKNLKTQNSDLASTANMLREQVAQLKQKVMNHVNSGCQLMLTQQLQTF
InterPro domains: - IPR046347: Basic-leucine zipper domain superfamily (homologous_superfamily) [271-310]
- IPR002112: Transcription factor Jun (family) [235-319]
- IPR004827: Basic-leucine zipper domain (domain) [246-311]
- IPR005643: Jun-like transcription factor (domain) [6-236]
- IPR008917: Transcription factor, Skn-1-like, DNA-binding domain superfamily (homologous_superfamily) [237-273]
- IPR050946: AP-1 Transcription Factor bZIP (family) [5-327]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0005515 (protein binding), GO:0008134 (transcription factor binding), GO:0001216 (DNA-binding transcription activator activity), GO:0046983 (protein dimerization activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific), GO:0001228 (DNA-binding transcription activator activity, RNA polymerase II-specific), GO:0140297 (DNA-binding transcription factor binding), GO:0042803 (protein homodimerization activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0042742 (defense response to bacterium), GO:0050829 (defense response to Gram-negative bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: DNA-(Apurinic or apyrimidinic site) lyase, putative (EC 4.2.99.18) (Q383L5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MFLISWNVAGWGSTARLIRSDFGTIAEFLRHTQADIVCLQEVKGSWQKLKDEPYAMGAGDGRPVSVEGWESFWSFSGRGQRGFNGVATFARKGLTWWCDSRPFIEADDKEGNSSPDASDKKTSTVEELHDEGRVLVTGHSAFVLVNTYVVNGRNSQRMAFKMRFLSCLKSLLARLKKENGKPVILVGDLNITFRAEDSHWSQRRLGFPSFMRLVHLARSLSNDEWKQSYPYIGQDTVCHLEGYIAEQTLQFLVDESDDPHPNDGRCARVDNLFSGLTKECKTTVTIDGNHLLQELVQKGRELKYHQNKGSGARVTLSELCEAGVTSVFASTLLRMQQTNHNRDIFVLVQYCGLPSHDEAGVEFMKELLVDLNLRDTMLVGLTPEALNDVCPCPYTCWDQSKNKRVVNEGNRIDYILIDASLAPKLAPCRDTENNVVRTLSEGIGHAGEDNGKKVVVDGCENTSSPFFSEFDGASHLLGVQRTAGHGAYPAAAMDGTGLPPLKKEARDLQFRGLPSTGLFVTPPQYSDHCGVCAYFPDLLLEPRPAKVKEIHPCLYRLPASLESFFQKRPRSE
InterPro domains: - IPR005135: Endonuclease/exonuclease/phosphatase (domain) [5-273]
- IPR036691: Endonuclease/exonuclease/phosphatase superfamily (homologous_superfamily) [1-535]
- IPR004808: AP endonuclease 1 (family) [1-532]
- IPR020847: AP endonuclease 1, binding site (binding_site) [34-43]
Interaction partners: - Protein artemis
- Endonuclease III homolog lyase)
- Proliferating cell nuclear antigen
- DNA-
- Flap endonuclease 1
- Adenine DNA glycosylase
- Uracil-DNA glycosylase
- Sm protein F
- Small nuclear ribonucleoprotein E
- Small nuclear ribonucleoprotein Sm D2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0016791 (phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:1901657 (glycosyl compound metabolic process), GO:0009116 (nucleoside metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: H2-M beta chain (Q31098)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Sequence: GGFVAHVESTCVLNDAGTPQDFTYCVSFNKDLLACWDPDVGKIVPCEFGVLSRLAEIISNILNEQESLIHRLQNGLQDCATHTQPFWDVLTHRTRAPSVRVAQTTPFNTREPVMLACYVWSFYPADVTITWMKNGQLVPSHSNKEKTAQPNGDWTYQTVSYLALTPSYGDVYTCVVQHSGTSEPIRGDW
InterPro domains: - IPR011162: MHC classes I/II-like antigen recognition protein (homologous_superfamily) [2-95]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [93-188]
- IPR050160: Major Histocompatibility Complex/Immunoglobulin (family) [4-189]
- IPR014745: MHC class II, alpha/beta chain, N-terminal (homologous_superfamily) [2-92]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [93-189]
- IPR007110: Immunoglobulin-like domain (domain) [97-186]
- IPR000353: MHC class II, beta chain, N-terminal (domain) [9-88]
- IPR003006: Immunoglobulin/major histocompatibility complex, conserved site (conserved_site) [172-178]
- IPR003597: Immunoglobulin C1-set (domain) [100-184]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0019882 (antigen processing and presentation), GO:0006457 (protein folding), GO:0006458 ('de novo' protein folding), GO:0002504 (antigen processing and presentation of peptide or polysaccharide antigen via MHC class II), GO:0061077 (chaperone-mediated protein folding), GO:0019884 (antigen processing and presentation of exogenous antigen), GO:0048002 (antigen processing and presentation of peptide antigen), GO:0002495 (antigen processing and presentation of peptide antigen via MHC class II), GO:0051084 ('de novo' post-translational protein folding), GO:0002478 (antigen processing and presentation of exogenous peptide antigen), GO:0051085 (chaperone cofactor-dependent protein refolding), GO:0019886 (antigen processing and presentation of exogenous peptide antigen via MHC class II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0005773 (vacuole), GO:0043227 (membrane-bounded organelle), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0012506 (vesicle membrane), GO:0005770 (late endosome), GO:0005774 (vacuolar membrane), GO:0010008 (endosome membrane), GO:0031982 (vesicle), GO:0030659 (cytoplasmic vesicle membrane), GO:0005771 (multivesicular body), GO:0005764 (lysosome), GO:0097708 (intracellular vesicle), GO:0098852 (lytic vacuole membrane), GO:0005765 (lysosomal membrane)
Protein: Cleavage stimulation factor subunit 2 (A0A8I5ZY65)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MAGLPVRDPAVDRSLRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGTGAPVIESPYGESISPEDAPESISKAVASLPPEQMFELMKQMKLCVQNSPQEARNMLLQNPQLAYALLQAQVVMRIVDPEIALKILHRQTNIPTLISGNPQPVHVAGPGSGPNVSMNQQNPQAPQAQSLSGMHVNGAPPMMQASMPGGVPAPVQMAAAVAGPGPGSLAPAGVMQAQVGMQGAGPVPMERGQGDAPNDPRGGTLMTVTGEVEPRAYLGPPPPPHQGPPMHHVPGHEGRGPPPHDMRGGPLAEPRPLMAEPRGPMLDQRGPPLDARGGRDPRGLDARGMEARAMEARGLEARAMEARAMEARAMEARAMEARAMEARAMEARGMDTRGPVPGPRGPIPSGIQGPNPMNMGAVVPQGSRQVPVMQGAGMQGASMQGGSQPGGFSPGQSQVTPQDHEKAALIMQVLQLTADQIAMLPPEQRQSILILKEQIQKSTGAP
InterPro domains: - IPR035979: RNA-binding domain superfamily (homologous_superfamily) [9-99]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [8-111]
- IPR025742: Cleavage stimulation factor subunit 2, hinge domain (domain) [113-191]
- IPR026896: Transcription termination and cleavage factor, C-terminal domain (domain) [505-545]
- IPR000504: RNA recognition motif domain (domain) [16-94]
- IPR038192: Transcription termination and cleavage factor, C-terminal domain superfamily (homologous_superfamily) [501-549]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009719 (response to endogenous stimulus), GO:0071495 (cellular response to endogenous stimulus), GO:0070848 (response to growth factor), GO:0071363 (cellular response to growth factor stimulus), GO:1990089 (response to nerve growth factor), GO:1990090 (cellular response to nerve growth factor stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016604 (nuclear body), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0016607 (nuclear speck), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase (EC 2.1.1.57) (Q385S9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Virion {ECO:0000256|ARBA:ARBA00004328}.
Sequence: MNFPDSRVLSDEFPRRKYKPSSATRLEDIVLKGLHYGQRKLLLSEIEFLSAYLEGRQAGAKPTLVVYAGAANGSHLPFLFQLFEAVKFVLIDPAPFCDAVREISLNKQGPILDLVQGFCTDELCKQLSSSYGSTYDILLVSDIRSGVPEKQSNRENTLMIMRDNDMQRSWCWTLKAEAALLKFHPPYPPCRDRNSRHYDEADDTPESIEYLDGVRLFGVWAPKSSSELRLCVQGPFLQGTSFPMRRYDCTTHEEQCYFYNTDNRYTRDCAAESGILERYLQLFPSAPYSDPTALSMTISNFLGFPLFLPLDSSFSESDARWVTLLYSTRIPTCLELFTTLRGRVTHTVMKQLAEEWQSATTVPKGVSIDSVELTSEFWKAVCAGDLTEAYSFPNIRWRFANLLISRRRKRSASDRAP
InterPro domains: - IPR025804: Poxvirus/kinetoplastid-type cap-specific nucleoside 2-O-methyltransferase (family) [1-282]
- IPR000176: mRNA methyltransferase-like (family) [35-264]
- IPR029063: S-adenosyl-L-methionine-dependent methyltransferase superfamily (homologous_superfamily) [2-304]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0008194 (UDP-glycosyltransferase activity), GO:0046527 (glucosyltransferase activity), GO:0035251 (UDP-glucosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0032259 (methylation), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0043414 (macromolecule methylation), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0043412 (macromolecule modification), GO:0090304 (nucleic acid metabolic process), GO:0001510 (RNA methylation), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0009451 (RNA modification), GO:0034470 (ncRNA processing), GO:0036260 (RNA capping), GO:0034660 (ncRNA metabolic process), GO:0006399 (tRNA metabolic process), GO:0008033 (tRNA processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)
Protein: Transcriptional regulator NarO (Bacterioopsin transcriptional activator) (DNA-binding protein NarO) (D4GPG1)
Organism: Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)
Function: Activates transcription of the denitrifying genes (nitrate reductase narA and nitrite reductase nirK) under anaerobic conditions.
Sequence: MNEGVHGEIHVADPSICRVSEASKETAVESVSRSVGATGDTAAVEFTAPSSAAIDDADEIFHHEQKTIYRVTHSFTEESRCACELIEGHGCPVRHLEADCGAVVLSFVAADLESFRDIVVNLKSAFDGVSLRRLTQSEPDSATGSLVFVDRDELTARQREVLETAHEMGYFEHPREANATEVAAALDINRSTFTEHLSAAQSKLLDTILDV
InterPro domains: - IPR007050: Bacterioopsin activator-type, HTH domain (domain) [154-205]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [151-207]
- IPR056433: DmsR-like, N-terminal (domain) [1-137]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0048584 (positive regulation of response to stimulus), GO:0032101 (regulation of response to external stimulus), GO:0032103 (positive regulation of response to external stimulus), GO:0032106 (positive regulation of response to extracellular stimulus), GO:0032104 (regulation of response to extracellular stimulus), GO:0032109 (positive regulation of response to nutrient levels), GO:0032107 (regulation of response to nutrient levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0032993 (protein-DNA complex)