Protein: Ammonium-dependent carbamoyl phosphate synthetase (EC 6.3.4.16) (EC 6.3.5.5) (Arginine-specific carbamoyl phosphate synthetase, ammonia chain) (Glutamine-dependent carbamoyl phosphate synthetase) (Q5B0D1)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Not known
Sequence: MVLAARCGQATSSLLRQRCLAETRRSALALRSFTSPSTTRSTASALRLQQKTPSPWRSQQLRNFSSALCRLAAESSSVGDSLFSSGIVNPGANLVDVKKVLVIGSGGLSIGQAGEFDYSGSQALKALKEAGVQSVLINPNIATIQTDHKLADEVYYLPVTPEYVTYVIERERPDGIFLSFGGQTALNLGVQMNRMGTFERYGVRVLGTSIKTLETSEDRDLFAKALNEINIPIAESIAVGTVDEALKAADEVGYPIIVRSAYALGGLGSGFANNPEELKNLASRSLTLSPQILVEKSLRGWKEVEYEVVRDASNNCITVCNMENFDPLGIHTGDSIVVAPSQTLSDEEYHMLRTAAIKIVRHLGVVGECNVQYALQPDGLDYRVIEVNARLSRSSALASKATGYPLAYTAAKIGLGHTLPELPNAVTKTTTANFEPSLDYIVTKIPRWDLSKFQHVNRDIGSAMKSVGEVMAIGRTFEESFQKAIRQVDPRFVGFQGDKFENLDEVLKNPTDRRWLAVGQAMLHENYSVDKVHELTKIDKWFLYKLQNIVDNHNELKEIGSLFGVNKELMLKSKKLGFSDKQIAQLVGASEDDVRARRKGFGIRPWVKKIDTLAAEFPADTNYLYTTYNATSHDVTFDDHGTIILGSGVYRIGSSVEFDWCAVNATLSLRNMGKKTVMINYNPETYSTDFDTADKLYFEELSYERVMDIYELESASGVVVSVGGQLPQNIALRLQETGGANVLGTNPKDIDNAEDRHKFSQILDSIGVDQPAWKELTSVAEAERFAEAVGYPVLVRPSYVLSGAAMSVIHSQDELKEKLLNASAVSPDHPVVITKFIEGAQEIDVDAVASNGKLLLHAISEHVEPAGVHSGDATLVLPPASLEKPVMSRVKEIAEKVAKAWNITGPFNMQIIKADQEGAEPQLKVIECNLRASRSFPFVSKVLGTNFIDVATKALVGRDVPEPVDLMEVKRDYLATKVPQFSWTRLAGADPFLGVEMASTGEIACFGKDVVEAYWASLQSTMNFRVPEPGEGILLGGDITNPALAQIVDLLHPLGFKFFAASPEVKAHIESATKEHTPVQVIEFPKKDKRALREVFQKYDIRGCFNLAKTRGKTLLDEDYVMRRNAVDFGVPLFMETKTAQLFAQAMNQKLPRPEGIPSEVRTWSNFVGGKLL
InterPro domains: - IPR016185: Pre-ATP-grasp domain superfamily (homologous_superfamily) [95-757]
- IPR005480: Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (domain) [503-628]
- IPR011761: ATP-grasp fold (domain) [223-956]
- IPR011607: Methylglyoxal synthase-like domain (domain) [1024-1173]
- IPR058047: Carbamoyl phosphate synthase, preATP-grasp domain (domain) [97-751]
- IPR005483: Carbamoyl phosphate synthase, CPSase domain (domain) [109-484]
- IPR005479: Carbamoyl phosphate synthase, ATP-binding domain (domain) [218-959]
- IPR036897: Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily (homologous_superfamily) [482-635]
- IPR036914: Methylglyoxal synthase-like domain superfamily (homologous_superfamily) [1024-1162]
- IPR006275: Carbamoyl-phosphate synthase, large subunit (family) [95-1147]
- IPR013815: ATP-grasp fold, subdomain 1 (homologous_superfamily) [768-837]
Interaction partners: - Argininosuccinate synthase
- Amidophosphoribosyltransferase
- Carbamoyl phosphate synthase arginine-specific small chain
- Ornithine carbamoyltransferase, mitochondrial
- Acetylglutamate kinase
- Glutamate synthase
- glutamine--fructose-6-phosphate transaminase
- Glutamine synthetase
- Glutamine synthetase
- Dihydroorotate dehydrogenase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016874 (ligase activity), GO:0016879 (ligase activity, forming carbon-nitrogen bonds), GO:0016884 (carbon-nitrogen ligase activity, with glutamine as amido-N-donor)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006520 (amino acid metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0006082 (organic acid metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0008652 (amino acid biosynthetic process), GO:0016053 (organic acid biosynthetic process), GO:0043436 (oxoacid metabolic process), GO:1901605 (alpha-amino acid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0009064 (glutamine family amino acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process), GO:1901607 (alpha-amino acid biosynthetic process), GO:0009084 (glutamine family amino acid biosynthetic process), GO:0006525 (arginine metabolic process), GO:0006526 (arginine biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:1990204 (oxidoreductase complex)