Protein: GATA-binding protein 1 (A0A2R8QT05)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
Sequence: MENSSEPSRWVSPGLLSPDPLVNYTTDSGLLPPVDVDEPFYSSSETDLLPSYYSTSVQSRASSSYRHSPVRQVYSSQSILGNIQWLDNSAGHSLNSPYNPTSTVWSSSPFAKTPLHSHTSTSIYQNTATPSFTSPKEGFPSPSRDGKDSPRLQEVLKAERLSPMSGSGSSFLNLSSATGGVYGPSPHMLSPYGSYMSTSQDYSSAALYSTGGPWMSPSSYSPKLRNKMRLSPPEARECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIRPKKRLIVSKRAGTQCANCHTSTTTLWRRNASGEPVCNACGLYFKLHNVNRPLTMKKDGIQTRNRKVSNRNKKGKKNAASEVYPDMSHMAPPDEHVGAYSLNPGPLLSYSHPAHLLPTSTLHSSTTLPYTHHPNSGMMPTLV
InterPro domains: - IPR013088: Zinc finger, NHR/GATA-type (homologous_superfamily) [233-345]
- IPR016374: Transcription factor, GATA-2/3 (family) [21-416]
- IPR039355: Transcription factor GATA (family) [60-408]
- IPR000679: Zinc finger, GATA-type (domain) [232-342]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0042592 (homeostatic process), GO:0002376 (immune system process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0002682 (regulation of immune system process), GO:0051239 (regulation of multicellular organismal process), GO:0048871 (multicellular organismal-level homeostasis), GO:0009892 (negative regulation of metabolic process), GO:0050793 (regulation of developmental process), GO:0048522 (positive regulation of cellular process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0002262 (myeloid cell homeostasis), GO:0048523 (negative regulation of cellular process), GO:0060548 (negative regulation of cell death), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048513 (animal organ development), GO:0060255 (regulation of macromolecule metabolic process), GO:1903706 (regulation of hemopoiesis), GO:0009891 (positive regulation of biosynthetic process), GO:0048872 (homeostasis of number of cells), GO:2000026 (regulation of multicellular organismal development), GO:0034101 (erythrocyte homeostasis), GO:0010941 (regulation of cell death), GO:0031325 (positive regulation of cellular metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0045595 (regulation of cell differentiation), GO:0009790 (embryo development), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0030097 (hemopoiesis), GO:0002521 (leukocyte differentiation), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:0060284 (regulation of cell development), GO:0030099 (myeloid cell differentiation), GO:0010468 (regulation of gene expression), GO:0045637 (regulation of myeloid cell differentiation), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0048568 (embryonic organ development), GO:0030218 (erythrocyte differentiation), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010629 (negative regulation of gene expression), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0009792 (embryo development ending in birth or egg hatching), GO:0061515 (myeloid cell development), GO:0043009 (chordate embryonic development), GO:0042981 (regulation of apoptotic process), GO:0043066 (negative regulation of apoptotic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0035162 (embryonic hemopoiesis), GO:0048821 (erythrocyte development), GO:1903131 (mononuclear cell differentiation), GO:1902680 (positive regulation of RNA biosynthetic process), GO:0002573 (myeloid leukocyte differentiation), GO:0006357 (regulation of transcription by RNA polymerase II), GO:0030851 (granulocyte differentiation), GO:0045893 (positive regulation of DNA-templated transcription), GO:0030224 (monocyte differentiation), GO:0060215 (primitive hemopoiesis), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0030225 (macrophage differentiation), GO:0045944 (positive regulation of transcription by RNA polymerase II), GO:0030223 (neutrophil differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)