wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: C-type lectin domain family 3, member B (D3ZUU6)
Organism: Rattus norvegicus (Rat)
Function: Not known
Sequence: MGFWGTYLLFCLFSFLSQATTESPTPKTKKAATAKKDLVSPKMFEELKNRLDVLAQEVALLKEKQALQTVCLKGTKVNLKCLLAFTQPKTFHEASEDCISQGGTLGTPQSELENEALFEYARQSVGSEAELWLGLNDMASEGAWVDMTGGRLAYKNWETEITTQPDGGKAENCAALSGAANGKWFDKRCRDQLPYICQFAIV
InterPro domains: - IPR051663: C-type lectin and Tetranectin domain-containing protein (family) [4-202]
- IPR016186: C-type lectin-like/link domain superfamily (homologous_superfamily) [66-202]
- IPR018378: C-type lectin, conserved site (conserved_site) [173-197]
- IPR016187: C-type lectin fold (homologous_superfamily) [67-199]
- IPR001304: C-type lectin-like (domain) [71-199]
Interaction partners: - Plasminogen
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0030246 (carbohydrate binding), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0005509 (calcium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0001503 (ossification), GO:0048856 (anatomical structure development), GO:0009888 (tissue development), GO:0048513 (animal organ development), GO:0030282 (bone mineralization), GO:0031214 (biomineral tissue development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005615 (extracellular space), GO:0031012 (extracellular matrix)
Protein: Small ribosomal subunit protein mS45 (37S ribosomal protein S35, mitochondrial) (O60096)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for mitochondrial protein synthesis. Has a role in mitochondrial integrity and cell respiration.
Subcellular location: Mitochondrion {ECO:0000269|PubMed:18245278}.
Sequence: MRNSVEFSQLGLKTAFNLSQNKTYTSAVKKQFFSTGAFLSNGGNIDLNKHTQKNIDSKYVACNSRSVTPPNDVASSVSKNTLRHKQRLMMAQWLMSPEVQKAKSSSSGNVGLGPNTNQPFPLNPFFKPPRPISHSLRMKITDEYLQGASIEVLARKFNTSPQRIEALIKLRRINDEFEEKKKPILHSYNEVMEKMLNACTKPEMMQFNDGNDIPLRSNPVSLWKSLPEGETFTPQEAAKILKWPSIEELNMRQNATHFHKTSDEHKDLNEDEELISSSPSEVGKRVFRLIDLSTGNVYRRDTGGDIYVKRKKSTT
InterPro domains: - IPR021036: Small ribosomal subunit protein mS45 (family) [25-313]
Interaction partners: - Small ribosomal subunit protein uS4m
- Small ribosomal subunit protein bS18m
- Small ribosomal subunit protein uS11m
- Small ribosomal subunit protein uS5m
- Small ribosomal subunit protein mS35
- Small ribosomal subunit protein bS16m
- Small ribosomal subunit protein mS29
- Small ribosomal subunit protein uS7m
- Small ribosomal subunit protein uS12m
- Small ribosomal subunit protein uS15m
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0019538 (protein metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006412 (translation), GO:0009059 (macromolecule biosynthetic process), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:0006518 (peptide metabolic process), GO:0010467 (gene expression), GO:0140053 (mitochondrial gene expression), GO:0043043 (peptide biosynthetic process), GO:0032543 (mitochondrial translation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Claudin domain-containing protein 2 (Q8NHS1)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Sequence: MGVKRSLQSGGILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECNHGICSSIPCQTTLAVTVACMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKNAWKNNVFFSWSYFSGWLALPFSILAGFCFLLADMIMQSTDAISGFPVCL
InterPro domains: - IPR004032: PMP-22/EMP/MP20 (family) [21-45]
- IPR004031: PMP-22/EMP/MP20/Claudin (family) [10-145]
- IPR050579: Peripheral myelin protein 22/Epithelial membrane protein-like (family) [8-151]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0001562 (response to protozoan), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0042832 (defense response to protozoan)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Lipopolysaccharide export system protein LptC (Q9KP51)
Organism: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Function: Not known
Subcellular location: Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_01915}; Single-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_01915}.
Sequence: MSLSRIVYVLLLFIASWSLYYLLGQEQDSKIQVAPNLELPMFSGENLENISYDEQGIRNYVITSIHLDHYAKSGNTLFKAPILKVYREGTLQEWEITARRGILSKDQVLTLYDDVLAKNLLPDSGFDTLTTSEMSIQLKSRDFWADKPVELRGPQFETHGQAMKGNFADHSAELYNQVQGRYETLTP
InterPro domains: - IPR026265: Lipopolysaccharide export system protein LptC (family) [3-185]
- IPR052363: Lipopolysaccharide export system LptC (family) [1-184]
- IPR010664: Lipopolysaccharide assembly, LptC-related (family) [9-183]
Interaction partners: - Lipopolysaccharide export system ATP-binding protein LptB
- Lipopolysaccharide export system protein LptA
- Uncharacterized protein
- Lipopolysaccharide export system permease protein LptF
- 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC
- Arabinose 5-phosphate isomerase
- LPS-assembly lipoprotein LptE
- LPS-assembly protein LptD
- Der GTPase-activating protein YihI
- Lipoprotein NlpI
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0033036 (macromolecule localization), GO:0010876 (lipid localization), GO:0006810 (transport), GO:0006869 (lipid transport), GO:0071702 (organic substance transport), GO:1901264 (carbohydrate derivative transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0031975 (envelope), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:1990351 (transporter complex), GO:0005886 (plasma membrane), GO:0030313 (cell envelope)
Protein: Kappa-casein (B2Z898)
Organism: Bos taurus (Bovine)
Function: Not known
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Sequence: TEIPTINTIASGEPTSTPTIEAVESTVATLEASPEVIESPPEINTVQVTSTAV
InterPro domains: - IPR000117: Kappa casein (family) [1-53]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0044085 (cellular component biogenesis), GO:0016043 (cellular component organization), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0097305 (response to alcohol), GO:1901654 (response to ketone), GO:0032355 (response to estradiol), GO:0033993 (response to lipid), GO:0048545 (response to steroid hormone), GO:0043933 (protein-containing complex organization), GO:0014070 (response to organic cyclic compound), GO:0022607 (cellular component assembly), GO:0032570 (response to progesterone), GO:0065003 (protein-containing complex assembly), GO:0031960 (response to corticosteroid), GO:0051259 (protein complex oligomerization), GO:0051385 (response to mineralocorticoid), GO:0051260 (protein homooligomerization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Chaperone protein DnaK (HSP70) (Heat shock 70 kDa protein) (Heat shock protein 70) (Q9K0N4)
Organism: Neisseria meningitidis serogroup B (strain ATCC BAA-335 / MC58)
Function: Acts as a chaperone.
Sequence: MAKVIGIDLGTTNSCLAISENGQTKVIENAEGARTTPSVIAYLDGGEILVGAPAKRQAVTNAKNTIYAAKRLIGHKFEDKEVQRDIESMPFEIIKANNGDAWVKAQGKELSPPQISAEVLRKMKEAAEAYLGEKVTEAVITVPAYFNDSQRQATKDAGRIAGLDVKRIINEPTAAALAFGMDKGDNKDRKVAVYDLGGGTFDISIIEIANLDGDKQFEVLATNGDTFLGGEDFDQRLIDHIIAEFKKEQGIDLKQDVMALQRLKEAAEKAKIELSSGQQTEINLPYITMDATGPKHLAMKITRAKFESLVEDLITRSIEPCKIALKDAGLSTGDIDDVILVGGQSRMPKVQEAVKAFFGKEPRKDVNPDEAVAVGAAIQGEVLSGGRSDVLLLDVTPLSLGIETMGGVMTKLIQKNTTIPTKASQVFSTAEDNQSAVTIHVLQGERERASANKSLGQFNLGDIAPAPRGMPQIEVTFDIDANGILHVSAKDKGTGKAANITIQGSSGLSEEEIERMVKDAEANAEEDKKLTELVASRNQAEALIHSVKKSLADYGDKLDAAEKEKIEAALKEAEEAVKGDDKAAIDAKTEALGAASQKLGEMVYAQAQAEAQAGESEQANASAKKDDDVVDADFEEVKDDKK
InterPro domains: - IPR029048: Heat shock protein 70kD, C-terminal domain superfamily (homologous_superfamily) [508-615]
- IPR012725: Chaperone DnaK (family) [1-637]
- IPR013126: Heat shock protein 70 family (family) [4-604]
- IPR018181: Heat shock protein 70, conserved site (conserved_site) [7-352]
- IPR029047: Heat shock protein 70kD, peptide-binding domain superfamily (homologous_superfamily) [385-541]
- IPR043129: ATPase, nucleotide binding domain (homologous_superfamily) [4-383]
Interaction partners: - Chaperone protein DnaJ
- Protein GrpE
- Chaperonin GroEL
- Co-chaperonin GroES
- DnaJ protein, truncation
- Chaperone protein ClpB
- Co-chaperone protein HscB homolog
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0051087 (chaperone binding), GO:0019904 (protein domain specific binding)
Biological Process (BP): GO:0008150 (biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0044403 (biological process involved in symbiotic interaction), GO:0051701 (biological process involved in interaction with host), GO:0044406 (adhesion of symbiont to host)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0022624 (proteasome accessory complex), GO:1902494 (catalytic complex), GO:0005622 (intracellular anatomical structure), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0140535 (intracellular protein-containing complex), GO:1905368 (peptidase complex), GO:0000502 (proteasome complex), GO:0005886 (plasma membrane), GO:1905369 (endopeptidase complex)
Protein: S protein (Q91QT1)
Organism: Avian infectious bronchitis virus (strain Beaudette US) (IBV)
Function: Not known
Subcellular location: Host endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000256|ARBA:ARBA00034689}. Virion membrane {ECO:0000256|ARBA:ARBA00004182}.
Sequence: MLVTPLLLVTLLCALCSAVLYDSSSYVYYYQSAFRPPNGWHLQGGAYAVVNISSEFNNAGSSSGCTVGIIHGGRVVNASSIAMTAPSSGMAWSSSQFCTAHCNFSDTTVFVTHCYKHGGCPITGMLQQNLIRVSAMKNGQLFYNLTVSVAKYPTFRSFQCVNNLTSVYLNGDLVYTSNETIDVTSAGVYFKAGGPITYKVMREVKALAYFVNGTAQDVILCDGSPRGLLACQYNTGNFSDGFYPFTNSSLVKQKFIVYRENSVNTTCTLHNFIFHNETGANPNPSGVQNIQTYQTKTAQSGYYNFNFSFLSSFVYKESNFMYGSYHPSCKFRLETINNGLWFNSLTVSIAYGPLQGGCKQSVFKGRATCCYAYSYGGPSLCKGVYSGELDHNFECGLLVYVTKSGGSRIQTATEPPVITQNNYNNITLNTCVDYNIYGRTGQGFITNVTDSAVSYNYLADAGLAILDTSGSIDIFVVQGEYGLNYYKVNPCEDVNQQFVVSGGKLVGILTSRNETGSQLLENQFYIKITNGTRRFRRSITENVANCPYVSYGKFCIKPDGSIATIVPKQLEQFVAPLFNVTENVLIPNSFNLTVTDEYIQTRMDKVQINCLQYVCGSSLDCRKLFQQYRPVCDNILSVVNSVGQKEDMELLNFYSSTKPAGFNTPVLSNVSTGEFNISLLLTTPSSRRKRSLIEDLLFTSVESVGLPTNDAYKNCTAGPLGFFKDLACAREYNGLLVLPPIITAEMQAMYTSSLVASMAFGGITAAGAIPFATQLQARINHLGITQSLLLKNQEKIAASFNKAIGHMQEGFRSTSLALQQIQDVVSKQSAILTETMASLNKNFGAISSVIQEIYQQFDAIQANAQVDRLITGRLSSLSVLASAKQAEYIRVSQQRELATQKINECVKSQSIRYSFCGNGRHVLTIPQNAPNGIVFIHFSYTPDSFVNVTAIVGFCVKPANASQYAIVPANGRGIFIQVNGSYYITARDMYMPRAITAGDVVTLTSCQANYVSVNKTVITTFVDNDDFDFNDELSKWWNDTKHELPDFDKFNYTVPILDIDSEIDRIQGVIQGLNDSLIDLEKLSILKTYIKWPWYVWLAIAFATIIFILILGWVFFMTGCCGCCCGCFGIMPLMSKCGKKSSYYTTFDNDVVTEQYRPKKSV
InterPro domains: - IPR043473: Spike glycoprotein S2 superfamily, coronavirus (homologous_superfamily) [781-1081]
- IPR043614: Spike glycoprotein S2, coronavirus, C-terminal (domain) [1113-1161]
- IPR044873: Spike glycoprotein S2, coronavirus, heptad repeat 1 (domain) [769-874]
- IPR043607: Coronavirus spike glycoprotein S1, C-terminal (domain) [429-494]
- IPR044874: Spike glycoprotein S2, coronavirus, heptad repeat 2 (domain) [1024-1105]
- IPR002552: Spike glycoprotein S2, coronavirus (domain) [583-1110]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0016032 (viral process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0061024 (membrane organization), GO:0061025 (membrane fusion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Molybdate transporter 1 (A6YCJ2)
Organism: Chlamydomonas reinhardtii (Chlamydomonas smithii)
Function: High affinity molybdate transporter. Acts through an energy-dependent process.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Sequence: MALQNAWQNTKERARETWAQLTWSEVSGSLGDLGTFLPLLIGLVQKVHLDLGTTLTITGLYNIISGWQFRIPMCVQPMKTIAAVALAGGAAGLDLPQLLHAGLFVAGCVGLLGASQAIDLFNWLVPPPVIRGVQLAVGVKLAMKGVDMALRLHGGPSSGWRPWLGTEGLVVGAVALAAMIATTLPPRAARRGTLEAADEGGLGPRPTDTAFEPLLRRLPACCGGGDRAPQVEGAAVSAERAGLLAHAEGGERSGNLDDGTEAGVGAAAGGGGCGGGGGGGRIPSALIAVVVGLAMAVLHRPGLVWELRLGPTLPRLLRPSWPDFKTGALRGGLPQLPLTTLNSVIAVTQLANALFGDKPEAERRRWRPSAVALSVALLNGAGVWLGAMPCCHGAGGLAAQYKFGARTGHAPILLGCIKAALGLLFGGSLVVLLEAFPQPLLGALLTVSGIELASVVRHTRSPRGYTFALLTAVAILALDNTGTGFLVGLVGVAAVAAYEGAVAAAAARWPRVFARGGRA
InterPro domains: - IPR031563: Molybdate transporter 1/2 (family) [3-501]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0016740 (transferase activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0015103 (inorganic anion transmembrane transporter activity), GO:0016773 (phosphotransferase activity, alcohol group as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:0015711 (organic anion transport), GO:0006865 (amino acid transport), GO:0015849 (organic acid transport), GO:0015711 (organic anion transport), GO:0046942 (carboxylic acid transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0031090 (organelle membrane), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0070013 (intracellular organelle lumen), GO:0030659 (cytoplasmic vesicle membrane), GO:0012506 (vesicle membrane), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Coiled-coil-helix-coiled-coil-helix domain containing 3 (Q9D9P1)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00034476}; Lipid-anchor {ECO:0000256|ARBA:ARBA00034476}.
Sequence: MGGTASTRRVTFEADENENITVVKGIRLSENVIDRMKESSPSGSKSQRYSSVYGASVSDEDLKRRVAEELALEQAKKESEHQRRLKQARDLERERAAANEQLTRAVLRERISSEEERMKAKHLARQLEEKDRVMRKQDAFYKEQLARLEERSSEFYKVTTEEYQKAAEEVEAKFK
InterPro domains: - IPR052632: MICOS complex subunit Mic19 (family) [1-175]
- IPR007964: MICOS complex subunit MIC19/MIC25 (family) [29-174]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0060090 (molecular adaptor activity), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0050794 (regulation of cellular process), GO:0010646 (regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0008277 (regulation of G protein-coupled receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005740 (mitochondrial envelope), GO:0019866 (organelle inner membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031966 (mitochondrial membrane), GO:0005743 (mitochondrial inner membrane)
Protein: Anion exchange protein (Q7ZZJ7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane {ECO:0000256|RuleBase:RU362035}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU362035}.
Sequence: MMEAVSFDGDNDMSYEDSESPLPSPFTLTPAAHKGSYDLEQVRQQGEEQPQTFTFNRDLEAARNTNTNAIKRGDAESYVELNELRGEIWQETGRWVGFEENFSPATGQWSQSHVSYLTFKSLIQLRKVMSTGAVLLDVDDSSLSSIGQKMVEQLLLKKEIRPSDRDALVTILQRKRSQLEPVVSPGSADLELQTFSVTKQRDQVDRVEGSVVLSGVVENLQKPVVAFARLRDSVVMEGVLEASIPVRFVFFLVGPSHSGMDYHESGRAMAALMADWVFSLEAYLATNERDLYNAMADFMDCSIVIPPTDIQDDSMLKPIINFQKKMLHDRVRPYDTRIMVGGKAPTGPAKPREDPLARTGLPFGGMVKDIKRRYKHYLSDFTDALDPQVLSAVIFIYFAALSPAITFGGLLADKTEHMMGVSEMMVSTCVQGVIFCLFAAQPVLVIGFTGPLMVFEEAFFQFCKGYGFEYIVGRVWVGMWLIVIVVIIMAVEGSFLVRFISRFTQEIFSILISLIFIYETFSKLIKIFKAHPLILNYEHLNDSLDDPFHPIKKVINVTLHPDGNVTEHHEIIERAYPNTALLSMCLMFGCFFIALYLRGFKTSTYLPGPIRRMVGDFGVPIAIFFMIAVDISISDAYTQKLVVPKGLTVSNTSARGWFISPFGEKKTFPVWMMFACVVPAMLVFILIFLESQITTLIVSKPERKMVKGSGFHVDLLLLVFLGGVGSLFGVPWLSAATVRSVTHANALTVMTKGPRPQIERVLEQRVSGILVAVMVGVSILMEPILKMIPMTALFGIFLYMGITSLSGIQLWDRMLLLITPKKHHPAVPYVTRVPTMRMHLYTLIQVMCLALLWVVKSSNFSLALPFVLILTIPLRMFMTGHVFTVMEMKCLDADDANVKFDDEDD
InterPro domains: - IPR018241: Anion exchange, conserved site (conserved_site) [363-524]
- IPR013769: Band 3 cytoplasmic domain (domain) [76-311]
- IPR001717: Anion exchange protein (family) [388-902]
- IPR011531: Bicarbonate transporter-like, transmembrane domain (domain) [362-894]
- IPR003020: Bicarbonate transporter, eukaryotic (family) [75-904]
- IPR016152: Phosphotransferase/anion transporter (homologous_superfamily) [73-337]
Interaction partners: - Rhesus blood group-associated glycoprotein
- Protein 4.1
- Aquaporin 1a
- Ankyrin 1, erythrocytic b.
- 5-aminolevulinate synthase, erythroid-specific, mitochondrial
- Ankyrin 3a.
- Ankyrin 2b, neuronal.
- Carbonic anhydrase
- Glycophorin C
- Carbonic anhydrase II
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015106 (bicarbonate transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0006811 (monoatomic ion transport), GO:0071702 (organic substance transport), GO:0006812 (monoatomic cation transport), GO:0006816 (calcium ion transport), GO:0070509 (calcium ion import), GO:0030001 (metal ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0045178 (basal part of cell), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0009925 (basal plasma membrane), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0016323 (basolateral plasma membrane)