Protein: Membrane-associated sulfotransferase kil1 (EC 2.8.2.-) (Q55GK8)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Sulfotransferase involved in intracellular killing of bacteria.
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Sequence: MSTTSMILTKKNIIILSIIIITIIAYQFYITSPQSFPSSNTITNTINTSGKGLDYTELLNLQKDLKAQQTEIRKQLEQLKYSINDINQNQNENQNQINNEYNNNKLNDEQENNNNNNYNNNNNNNNNELINYKERIKKKSKEQPNTCIPVEGKLLCLPNFIVIGTMKSGTTFLDYYLQKHPQIAHHSKKEIWYFNSYYANGIEWYAKHFEQYTSLENQKLIGEATPFYINNPNTAPRLFTTLKNAKLILLLRDPVERSLSQYHFSIQWLKRNKSPPLEYSFEHLIHEEADVIETCIRGHERYKEAFKQRKEIEKNGGGGLLNDNTSGEEFNLVDPFYTLHSEKNWTFYKDCIRCDKCFQIGSILHTSGHPTFGMLAKSLYFEQLDYWLNFFPLEQIHIIRYEDISSQPESVLSELEDFLDINHIDYGEFKPRNVVQHDPMNQEIKSYLINYFKQSNEKLYNLLNRDFKWQN
InterPro domains: - IPR000863: Sulfotransferase domain (domain) [158-422]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [132-470]
- IPR037359: Heparan sulfate sulfotransferase (family) [9-470]
Interaction partners: - Intermembrane lipid transfer protein vps13F
- Putative phagocytic receptor 1a
- Integrin beta-like protein A
- Glycosyltransferase
- Large ribosomal subunit protein eL15
- Putative lysozyme-like protein
- Lysozyme A
- Putative phagocytic receptor 1b
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016782 (transferase activity, transferring sulphur-containing groups), GO:0008146 (sulfotransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0019637 (organophosphate metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0006793 (phosphorus metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0006753 (nucleoside phosphate metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0019693 (ribose phosphate metabolic process), GO:0018130 (heterocycle biosynthetic process), GO:0090407 (organophosphate biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0072521 (purine-containing compound metabolic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0009259 (ribonucleotide metabolic process), GO:0009141 (nucleoside triphosphate metabolic process), GO:0009117 (nucleotide metabolic process), GO:0046390 (ribose phosphate biosynthetic process), GO:0006163 (purine nucleotide metabolic process), GO:0072522 (purine-containing compound biosynthetic process), GO:1901293 (nucleoside phosphate biosynthetic process), GO:0009165 (nucleotide biosynthetic process), GO:0009144 (purine nucleoside triphosphate metabolic process), GO:0006164 (purine nucleotide biosynthetic process), GO:0009150 (purine ribonucleotide metabolic process), GO:0009260 (ribonucleotide biosynthetic process), GO:0009199 (ribonucleoside triphosphate metabolic process), GO:0009142 (nucleoside triphosphate biosynthetic process), GO:0009201 (ribonucleoside triphosphate biosynthetic process), GO:0009152 (purine ribonucleotide biosynthetic process), GO:0046034 (ATP metabolic process), GO:0009145 (purine nucleoside triphosphate biosynthetic process), GO:0009205 (purine ribonucleoside triphosphate metabolic process), GO:0006754 (ATP biosynthetic process), GO:0009206 (purine ribonucleoside triphosphate biosynthetic process), GO:0015986 (proton motive force-driven ATP synthesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)