wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: D-galactonate dehydratase family member Cbei_4837 (A6M2W4)
Organism: Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) (Clostridium acetobutylicum)
Function: Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.
Sequence: MEPTIITDVLCYITKPDRHNLVVVKVETNKGIYGLGCATFQQRPKAVSLVVSEYLKPILIGRDANNIEDLWQMMMVNSYWRNGPILNNAISGVDMALWDIKGKLANMPLYQLFGGKSRDAIAAYTHAVADNLEDLYTEIDEIRKKGYQHIRCQLGFYGGNSSEFHTTDNPTQGSYFDQDEYMRTTVSMFSSLREKYGYKFHILHDVHERLFPNQAVQFAKDVEKYKPYFIEDILPPDQNEWLGQIRSQTSTPLATGELFNNPMEWKSLIANRQVDFIRCHVSQIGGITPALKLGSLCAAFGVRIAWHTPSDITPIGVAVNIHLNINLHNAAIQENIEINDNTRCVFSGIPEAKNGFFYPIESPGIGVDIDENEIIKYPVEYRPHEWTQSRIPDGTIVTP
InterPro domains: - IPR029065: Enolase C-terminal domain-like (domain) [181-372]
- IPR018110: Mandelate racemase/muconate lactonizing enzyme, conserved site (conserved_site) [89-114]
- IPR013341: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain (domain) [18-114]
- IPR013342: Mandelate racemase/muconate lactonizing enzyme, C-terminal (domain) [132-252]
- IPR029017: Enolase-like, N-terminal (homologous_superfamily) [11-395]
- IPR034589: D-mannonate dehydratase-like (family) [5-398]
- IPR034593: D-galactonate dehydratase DgoD-like (family) [18-380]
- IPR036849: Enolase-like, C-terminal domain superfamily (homologous_superfamily) [102-380]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0000287 (magnesium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:1901575 (organic substance catabolic process), GO:0005975 (carbohydrate metabolic process), GO:0016052 (carbohydrate catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005618 (cell wall), GO:0009274 (peptidoglycan-based cell wall)
Protein: BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 (O54940)
Organism: Mus musculus (Mouse)
Function: Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Note=Localizes to the nuclear envelope region and to other cytoplasmic structures. {ECO:0000250}.
Sequence: MEGVELKEEWQDEDFPIPLPEDDSIEADTLDGTDPDRQPGSLEVNGNKVRKKLMAPDISLTLDPGEDSLWSDDLDEAGEVDLEGLDTPSENSDEFEWEDDLPKPKTTEVIRKGSITEYTATEEKGDGRRWRMFRIGEQDHRVDMKAIEPYKKVISHGGYYGDGLNAIVVFAVCFMPESGQPNYRYLMDNLFKYVIGTLELLVAENYMIIYLNGATTRRKMPSLGWLRRCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAELAELVPMEYVGIPECIKQYEEEKFKKRQKRVDQELNGKQEPPKSEQ
InterPro domains: - IPR036865: CRAL-TRIO lipid binding domain superfamily (homologous_superfamily) [145-306]
- IPR022181: Bcl2-/adenovirus E1B 19kDa-interacting protein 2 (family) [50-163]
- IPR001251: CRAL-TRIO lipid binding domain (domain) [147-304]
Interaction partners: - Apoptosis regulator Bcl-2
- Cell division control protein 42 homolog
- Rho GTPase-activating protein 1
- Mitogen-activated protein kinase 14
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0016043 (cellular component organization), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0022008 (neurogenesis), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0120036 (plasma membrane bounded cell projection organization), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005739 (mitochondrion), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043005 (neuron projection), GO:0005740 (mitochondrial envelope), GO:0043231 (intracellular membrane-bounded organelle), GO:0031966 (mitochondrial membrane)
Protein: Holocytochrome c-type synthase (EC 4.4.1.17) (A0A1D8PN32)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004273, ECO:0000256|RuleBase:RU363130}.
Sequence: MGWFWADKPSQDTVKATSFFTTPSACPIDHSKLASSSPTCPVKLNNDNDEVLNPLNNMPMAISSERAPGQRIKLSTERTISTIPRGESEDQGLWEYPSPQQMLNAMLSKGKGDGVPEDAVESMVEVHNFLNEGAWQQILTWEDQYTQQTKVEPRLKKFTGRPHDLSPKARMYLWLGQLFPETFNTIPPFDRHDWTVLRSCGRNQGWKEVRYVIDYYGAPDDEETGMPAFMLDTRPALDNLTNARDRFTHWAYPLWKKAMGEVRD
InterPro domains: - IPR000511: Holocytochrome c/c1 synthase (family) [1-259]
Interaction partners: - Protoheme IX farnesyltransferase, mitochondrial
- Holocytochrome c-type synthase
- Ferrochelatase
- Ubiquitin-conjugating enzyme E2 6
- Cytochrome c
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016846 (carbon-sulfur lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0009058 (biosynthetic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0016043 (cellular component organization), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044085 (cellular component biogenesis), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0009059 (macromolecule biosynthetic process), GO:0043933 (protein-containing complex organization), GO:0006996 (organelle organization), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly), GO:0007005 (mitochondrion organization), GO:0033108 (mitochondrial respiratory chain complex assembly), GO:0017004 (cytochrome complex assembly), GO:0008535 (respiratory chain complex IV assembly), GO:0033617 (mitochondrial cytochrome c oxidase assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005618 (cell wall), GO:0009277 (fungal-type cell wall), GO:0030446 (hyphal cell wall)
Protein: Prostate and testis expressed protein 14 (Secreted seminal-vesicle Ly-6 protein 1) (SSLP-1) (Q3UN54)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Secreted {ECO:0000269|PubMed:16940290}.
Sequence: MEKYLLLLLLGIFLRVGFLQALTCVSCGRLNSSGICETAETSCEATNNRKCALRLLYKDGKFQYGFQGCLGTCFNYTKTNNNMVKEHKCCDHQNLCNKP
InterPro domains: - IPR016054: Ly-6 antigen/uPA receptor-like (domain) [20-99]
Interaction partners: - Prostate and testis expressed protein 4
- Prostate and testis expressed 10
- Prostate and testis expressed protein 13
- Prostate and testis expressed protein 3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030545 (signaling receptor regulator activity), GO:0099602 (neurotransmitter receptor regulator activity), GO:0030548 (acetylcholine receptor regulator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0023051 (regulation of signaling), GO:0006950 (response to stress), GO:0050794 (regulation of cellular process), GO:0009611 (response to wounding), GO:0010646 (regulation of cell communication), GO:0099177 (regulation of trans-synaptic signaling), GO:0050804 (modulation of chemical synaptic transmission)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Replicative helicase loader DnaI (EC 3.6.4.-) (Primosomal protein DnaI) (P06567)
Organism: Bacillus subtilis (strain 168)
Function: Probably involved in DNA replication.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:10844689}. Note=Forms foci near both cell poles and in the middle of cells (PubMed:10844689). {ECO:0000269|PubMed:10844689}.
Sequence: MEPIGRSLQGVTGRPDFQKRLEQMKEKVMKDQDVQAFLKENEEVIDQKMIEKSLNKLYEYIEQSKNCSYCSEDENCNNLLEGYHPKLVVNGRSIDIEYYECPVKRKLDQQKKQQSLMKSMYIQQDLLGATFQQVDISDPSRLAMFQHVTDFLKSYNETGKGKGLYLYGKFGVGKTFMLAAIANELAEKEYSSMIVYVPEFVRELKNSLQDQTLEEKLNMVKTTPVLMLDDIGAESMTSWVRDEVIGTVLQHRMSQQLPTFFSSNFSPDELKHHFTYSQRGEKEEVKAARLMERILYLAAPIRLDGENRRHP
InterPro domains: - IPR009928: Primosomal DnaI, N-terminal (domain) [1-98]
- IPR003593: AAA+ ATPase domain (domain) [160-284]
- IPR013317: Chromosomal replication initiator protein DnaA, ATPAse domain (domain) [163-271]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [108-302]
Interaction partners: - Replicative DNA helicase DnaC
- Replicative helicase loading/DNA remodeling protein DnaB
- Replicative helicase loading/DNA remodeling protein DnaD
- Chromosomal replication initiator protein DnaA
- Beta sliding clamp
- DNA polymerase III PolC-type
- TVP38/TMEM64 family membrane protein YtxB
- DNA primase
- DNA polymerase III subunit tau
- Uncharacterized protein YtxC
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0043933 (protein-containing complex organization), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly), GO:0051259 (protein complex oligomerization), GO:0051260 (protein homooligomerization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0042597 (periplasmic space)
Protein: glucose-6-phosphate 1-epimerase (EC 5.1.3.15) (X2JAD3)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MATTAAAMAATSVVVLDRGNNTTCTINLHGATVVSWRVNNQEQLFVSKLASFDGKKAIRGGIPFVFPQFGAWSFGPQHGFARITRWHLERPPDRLHNGDVEAIFSLMDNDFTRSIWNYQFRITYRLILREKELHFHIGVYNPSKELSFTFNMLLHTYLKVPDVRRCQITGLQGCHFIDKTRENALYQEGREVVTVNEWTDRIYQHTPQEHVITNVVSGRKMRLHKYNFPDTVIWNPWIDRSREMSDFGDDEFPNMLCVEAGNVTSPVILLPGTAFEASQILQQFKCPYTIDPSSCRKKNYLTNFLQYD
InterPro domains: - IPR014718: Glycoside hydrolase-type carbohydrate-binding (homologous_superfamily) [2-284]
- IPR011013: Galactose mutarotase-like domain superfamily (homologous_superfamily) [15-281]
- IPR008183: Aldose 1-/Glucose-6-phosphate 1-epimerase (family) [13-281]
- IPR025532: Glucose-6-phosphate 1-epimerase (family) [1-287]
Interaction partners: - Phosphoglucomutase 1
- Hexokinase type 1
- Glucose-6-phosphate isomerase
- Phosphoglucomutase 2a
- Phosphoglucomutase 2b
- Hexokinase type 2
- Phosphotransferase
- Phosphotransferase
- LD24362p
- FI19814p1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016853 (isomerase activity), GO:0016854 (racemase and epimerase activity), GO:0016857 (racemase and epimerase activity, acting on carbohydrates and derivatives)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009615 (response to virus), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0140546 (defense response to symbiont), GO:0051607 (defense response to virus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Expansin-like protein 3 (Ddexpl3) (Q7KWS2)
Organism: Dictyostelium discoideum (Social amoeba)
Function: May serve to lubricate the movement of the cellulose microfibrils during cell growth and wall extension and/or may serve to maintain the fluid state of the slug cell wall.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Sequence: MKFNTIFLVLSIVKFILISAQSCPFSQSIINGASATFYTAIDAGNCGFEKLNGPLGPGNYMIAALGSKLYQNGAQCGQCFKISNSKNASVTVMATDSCHDAGYCQRDNHFDLSPAAFSILGPQSQGVLDGLSYVKVPCEVSGNVKIMMKDGSNDFWTSFFVFNSKVIIKQVSIKLSNSNQFVPLSQTTYNYWPTSITGGQFHVRIESIGGEFIYVTIPKVESRKVYETSGQFSTSCSNLNENNPINYKPQTFNSQQTSNNQNSNTQTPTKQPSPNSQNFIPSYCQQYIQKPNYIFAKESKEMLVLNENENIESNSLKLLPNFLLLILIILLNINF
InterPro domains: - IPR036749: Expansin, cellulose-binding-like domain superfamily (homologous_superfamily) [140-230]
- IPR051477: Plant Cell Wall Expansin (family) [19-236]
- IPR049818: Expansin EXLX1-like (family) [34-232]
- IPR007112: Expansin/pollen allergen, DPBB domain (domain) [43-143]
- IPR009009: RlpA-like protein, double-psi beta-barrel domain (domain) [63-128]
- IPR036908: RlpA-like domain superfamily (homologous_superfamily) [17-163]
Interaction partners: - Expansin-like protein 8
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0051703 (biological process involved in intraspecies interaction between organisms), GO:0099120 (socially cooperative development), GO:0048856 (anatomical structure development), GO:0031154 (culmination involved in sorocarp development), GO:0030587 (sorocarp development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix)
Protein: Flotillin-like protein 2 (D2XNQ9)
Organism: Medicago truncatula (Barrel medic) (Medicago tribuloides)
Function: May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles (By similarity). Required for early symbiotic events and nodules formation.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Membrane, caveola {ECO:0000250}. Note=In puncta evenly distributed in the cell membrane of root hair cells and polarly localized in root epidermal cells. No changes of localization upon inoculation with bacteria. {ECO:0000269|PubMed:20018678}.
Sequence: MKIYRVAKASEYLVITGIFIKDIKLKKKAWIFPGQSCTVLDLSPVNYTFEVQAMSAEKLPFVLPAVFTIGPRVDDQESLLKYAKLISPHDRHSNHVNELVQGIIEGETRVLAASMTMEEVFRGTKQFKQEVFDKVQLELNQFGLLIYNANVKQLVDVPGHEYFSYLGQKTQMEAKNQARVDVSEAKMKGEIGSKLREGQTLQNAAKIDAETKVIAMQRAGEGEKEGIKVRTEVKVFENQREAEVAQANSELAKKKAAWTKAAQVAEVEAKKAVALREAELQGEVERMNALTTTEKLKADLLSKASVQYETKVQEANWELYKKQKETEAILYEKKAEAEAQKASADATFYASKQAAEAELYAKKKEAEGIVTLGQAQGAYVSTLLNALGNDYTAVRDYLMINGDMFQEIAKINAEAIRGLEPKISIWTNGGDNSGGITDGAMGMKEVAGVYKMLPPLFKTVHEQTGMLPPAWMGALSEKSS
InterPro domains: - IPR001107: Band 7 domain (domain) [7-186]
- IPR027705: Flotillin family (family) [3-477]
- IPR036013: Band 7/SPFH domain superfamily (homologous_superfamily) [35-175]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0099402 (plant organ development), GO:0048731 (system development), GO:0048364 (root development), GO:0022622 (root system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0045177 (apical part of cell), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0016324 (apical plasma membrane)
Protein: Alliin lyase 1 (Alliinase-1) (EC 4.4.1.4) (Cysteine sulphoxide lyase 1) (Q01594)
Organism: Allium sativum (Garlic)
Function: Able to cleave the C-S bond of sulfoxide derivatives of Cys to produce allicin, thus giving rise to all sulfur compounds which are responsible for most of the properties of garlic, such as the specific smell and flavor as well as the health benefits like blood lipid or blood pressure lowering.
Subcellular location: Vacuole.
Sequence: MVESYKKIGSCNKMPCLVILTCIIMSNSLVNNNNMVQAKMTWTMKAAEEAEAVANINCSEHGRAFLDGIISEGSPKCECNTCYTGPDCSEKIQGCSADVASGDGLFLEEYWKQHKEASAVLVSPWHRMSYFFNPVSNFISFELEKTIKELHEVVGNAAAKDRYIVFGVGVTQLIHGLVISLSPNMTATPDAPESKVVAHAPFYPVFREQTKYFNKKGYVWAGNAANYVNVSNPEQYIEMVTSPNNPEGLLRHAVIKGCKSIYDMVYYWPHYTPIKYKADEDILLFTMSKFTGHSGSRFGWALIKDESVYNNLLNYMTKNTEGTPRETQLRSLKVLKEVVAMVKTQKGTMRDLNTFGFKKLRERWVNITALLDQSDRFSYQELPQSEYCNYFRRMRPPSPSYAWVKCEWEEDKDCYQTFQNGRINTQNGVGFEASSRYVRLSLIKTQDDFDQLMYYLKDMVKAKRKTPLIKQLFIDQTETASRRPFI
InterPro domains: - IPR006948: Alliinase, C-terminal (domain) [97-460]
- IPR037029: Alliinase, N-terminal domain superfamily (homologous_superfamily) [39-138]
- IPR006947: Alliinase, EGF-like domain (domain) [41-95]
- IPR015421: Pyridoxal phosphate-dependent transferase, major domain (homologous_superfamily) [139-348]
- IPR050478: Ethylene and sulfur compound biosynthesis-related protein (family) [112-457]
- IPR015424: Pyridoxal phosphate-dependent transferase (homologous_superfamily) [40-461]
- IPR015422: Pyridoxal phosphate-dependent transferase, small domain (homologous_superfamily) [349-461]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016846 (carbon-sulfur lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0042445 (hormone metabolic process), GO:0065008 (regulation of biological quality), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0009850 (auxin metabolic process), GO:0044249 (cellular biosynthetic process), GO:0042446 (hormone biosynthetic process), GO:0010817 (regulation of hormone levels), GO:0009851 (auxin biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0005773 (vacuole), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000325 (plant-type vacuole), GO:0043231 (intracellular membrane-bounded organelle)
Protein: AT5g16970/F2K13_120 (Putative quinone oxidoreductase) (Zinc-binding dehydrogenase family protein) (Q93Z72)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MTATNKQVVLKNYVSGFPKESDFDFKTTTVEFKLPGGSNSVLVKNLYLSCDPYMRIRMGKPDPSTAALAQAYAPGKPIFGYGVSRVIESGHPDYKKGDLLWGIVGWEEYSVITPMTHMHFKIQHTDIPLSYYTGLLGMPGMTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQFAKMMGCYVVGSAGSTEKVDLLKTKFGFDDAFNYKEEPDLSAALKRCFPTGIDIYFENVGGKMLDAVLLNMNPHGRIAVCGMISQYNLENQEGVHNLSNIIYKRIRIQGFAVFDFYEKYSKFLDFVLPHIKEGKITYVEDVADGLEKGPEALVGLFHGKNVGKQVVVIARE
InterPro domains: - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [134-304]
- IPR020843: Enoylreductase domain (domain) [41-340]
- IPR013149: Alcohol dehydrogenase-like, C-terminal (domain) [167-300]
- IPR011032: GroES-like superfamily (homologous_superfamily) [2-340]
- IPR045010: Medium-chain dehydrogenase/reductase (family) [4-345]
- IPR041694: Oxidoreductase, N-terminal domain (domain) [6-115]
Interaction partners: - At4g33840/F17I5_30
- Glycosyl hydrolase family 10 protein
- Glycosyl hydrolase family 10 protein
- Glycosyl hydrolase family 10 protein
- At4g38650
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0005515 (protein binding), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0006950 (response to stress), GO:0006979 (response to oxidative stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0009536 (plastid), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Killer cell lectin-like receptor subfamily H, member 1 (Q8K4F1)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Sequence: MQLSEMNEGRLTYAELKLSLKSKDKPQPTQKKREYPWRISVVILGTVCLCLLISSIVFGYLFFQGTSKFKIQCEKDANKNAVSSMEVVDPSALPPTTGKGCYKCQGRWFCCGEKCYYFSEEEKTWDESEASCRLLGSHLAKIDNREEQNFIQSRLNYSYWVGLRKKGGQFLWVHQEDEKISSDLDFHMTTHLADAACGYIKPKLLNNAQCSRLFPYICKKNFTCLLTSENW
InterPro domains: - IPR042808: C-type lectin domain family 7 member A (family) [6-224]
- IPR016186: C-type lectin-like/link domain superfamily (homologous_superfamily) [64-227]
- IPR016187: C-type lectin fold (homologous_superfamily) [90-223]
- IPR001304: C-type lectin-like (domain) [104-220]
- IPR033992: Natural killer cell receptor-like, C-type lectin-like domain (domain) [104-220]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003823 (antigen binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0065007 (biological regulation), GO:0048523 (negative regulation of cellular process), GO:0050794 (regulation of cellular process), GO:0060548 (negative regulation of cell death), GO:0010941 (regulation of cell death), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:0043066 (negative regulation of apoptotic process), GO:0042981 (regulation of apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)