Protein: Flagellar biosynthesis protein FlhF (Flagella-associated GTP-binding protein) (Q44758)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum (By similarity).
Subcellular location: Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
Sequence: MVQYFTEKGPTYNEVIEIIKKKYGKNARVMTYKTVPHGGILGLFSKDWVEVSGYVRYDIGNQQINVEDEKRKILQSIKREENSSIEDVLKEVKSLKTELAHKKENINHPTITKIEDILRENDFSENYIKDINEFIKREFSLSDLDDYERVREDVVLYIAKTIKCSGSIIDNLKKRVFILVGPTGVGKTTTIAKLAAIYGINGESKSLNIKIITIDNYRIGAKKQIQTYGDIMGIPVRAIESFKDLKDEITDSKDFDLILVDTIGKSPKDFMKLAEMKELLNACGRDAEFHLAVSSTTKTSDVKEIFHQFSPFNYKTVIFTKVDETTCVGNLISLIYEMKKVVSYVTDGQIVPHNISVAEPLTFIRRINGYRISDDAEFIKKIKSKSYY
InterPro domains: - IPR020006: Flagellar biosynthesis protein FlhF (family) [5-264]
- IPR000897: Signal recognition particle, SRP54 subunit, GTPase domain (domain) [174-369]
- IPR003593: AAA+ ATPase domain (domain) [173-356]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [169-357]
- IPR047040: Flagellar biosynthesis protein FlhF, GTPase domain (domain) [175-367]
Interaction partners: - Flagellar biosynthesis protein FlhA
- ATP-binding protein
- Flagellar motor switch protein FliM
- Flagellar biosynthetic protein FlhB
- Flagellar M-ring protein
- Flagellar protein FliZ
- Purine-binding chemotaxis protein
- Flagellar biosynthetic protein FliR
- Flagellar assembly protein FliH
- ATP-binding protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0016787 (hydrolase activity), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0097367 (carbohydrate derivative binding), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:1901265 (nucleoside phosphate binding), GO:0043168 (anion binding), GO:0000166 (nucleotide binding), GO:0032553 (ribonucleotide binding), GO:0035639 (purine ribonucleoside triphosphate binding), GO:0032555 (purine ribonucleotide binding), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0017076 (purine nucleotide binding), GO:0016462 (pyrophosphatase activity), GO:0005525 (GTP binding), GO:0019001 (guanyl nucleotide binding), GO:0032561 (guanyl ribonucleotide binding), GO:0017111 (ribonucleoside triphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0006970 (response to osmotic stress), GO:0001101 (response to acid chemical), GO:0009266 (response to temperature stimulus), GO:1901700 (response to oxygen-containing compound), GO:0009414 (response to water deprivation), GO:0010035 (response to inorganic substance), GO:0009415 (response to water), GO:0009409 (response to cold), GO:0010033 (response to organic substance), GO:1902074 (response to salt), GO:0009651 (response to salt stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)