Protein: Peroxisomal membrane protein PEX3 (PMP PEX3) (Peroxin-3) (Peroxisomal membrane protein PAS2) (C4R6F0)
Organism: Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris)
Function: Not known
Subcellular location: Peroxisome membrane {ECO:0000269|PubMed:10359594, ECO:0000269|PubMed:21576455, ECO:0000269|PubMed:8702562}; Single-pass membrane protein {ECO:0000255}. Note=Traffics to peroxisomes via the endolasmic reticulum (ER), where it accumulates in the absence of PEX19. {ECO:0000269|PubMed:21576455}.
Sequence: MLEYTAGLIRRNKKKFLISSGIIGVGYYVTKTINNKIQEFQNRIREENFAKEQIKRRFHQTQSDCYMTFLSLLPVLCEPIMDDLPVETITKQLQIRRLEKQIGNKDVKNSGSTVLSDDFSTSQEGAISEDTNKPPELKSKNQLWQELKIKAITRFLTLIYCESLLIVFLHLQLNILSRKSYLETAIRLASETQGIDLVDQESNGDFSGNTQDENLSEQAFLSFSWWLLNKGWLEIKNKIEPCVEQHFGGINPRQQLKINEFAELLNKCQNCIDLKVLNLTEDDIHLGVGVIEDQSQPVGRKSTNFITNALLPPKEFEFFLLQQTNDLDFLSRFNNNIVNTESLNMLLDELNNYLNNADINLIVNKLATLGITKVLDEIVLNLLQKNRPNPISDMNIRDIDLNDFPPYKLAALLANITKQSISLTNNSVENPILADLNNLPELNDLSASVYSNFDP
InterPro domains: - IPR006966: Peroxin-3 (family) [3-452]
Interaction partners: - PEX19 peroxisomal biogenesis protein
- Peripheral peroxisomal membrane peroxin
- Peroxisome assembly protein 12
- Peroxisomal membrane protein PEX13
- Peroxisomal membrane protein
- Peroxisomal membrane protein PEX14
- Mitochondrial fission 1 protein
- Mitochondrial protein involved in sorting of proteins in the mitochondria
- K+/H+ antiporter with a probable role in intracellular cation homeostasis
- Subunit of a heterodimeric peroxisomal ATP-binding cassette transporter complex
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0016043 (cellular component organization), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0006259 (DNA metabolic process), GO:0006996 (organelle organization), GO:0090304 (nucleic acid metabolic process), GO:0000723 (telomere maintenance), GO:0051276 (chromosome organization), GO:0032200 (telomere organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0042579 (microbody), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005777 (peroxisome), GO:0098588 (bounding membrane of organelle), GO:0031903 (microbody membrane), GO:0005778 (peroxisomal membrane)