Protein: Collagen alpha-1(XVI) chain (Q8BLX7)
Organism: Mus musculus (Mouse)
Function: Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Sequence: MLTSWAPGLWVLGLWATFSHGTNIGERCPTSQQEGLKLEHSSDPSTNVTGFNLIRRLNLMKTSAIKKIRNPKGPLILRLGAAPVTQPTRRVFPRGLPEEFALVLTVLLKKHTFRNTWYLFQVTDANGYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASVHVDCVSASSQPLGPRQSIRPGGHVFLGLDAEQGKPVSFDLQQAHIYCDPELVLEEGCCEILPGGCPPETSKSRRDTQSNELIEINPQTEGKVYTRCFCLEEPQNSKVDAQLMGRNIQKAERGTKVHQGTGVNECPPCAHSARESNVTLGPSGLKGGKGERGLTGPSGPKGEKGARGNDCVRVSPDAPLQCVEGPKGEKGESGDLGPPGLPGPTGQKGQKGEKGDGGLKGLPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGEKGSSGIPGKEGPGGKPGKPGVPGTKGEKGDPCEVCPTLPEGSQNFVGLPGKPGPKGEPGDPAPAWEGLGTVGLKGDRGDPGIQGMKGEKGEPCSSCSSGVGAQHLGPSPGHGLPGLPGTSGIPGPRGLKGEKGSFGDTGPAGVPGSPGPVGPAGIKGAKGEPCEPCTALSELQDGDMRVVHLPGPAGEKGEPGSPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGITGQPGISGEPGIRGPAGPKGEKGDGCTACPSLQGALTDVSGLPGKPGPKGEPGPEGVGHPGKPGQPGLPGVQGPPGPKGTQGEPGPPGTGAEGPQGEPGTQGLPGTQGLPGPRGPPGSAGEKGAQGSPGPKGAIGPMGPPGAGVSGPPGQKGSRGEKGEPGECSCPSRGEPIFSGMPGAPGLWMGSSSQPGPQGPPGVPGPPGPPGMPGLQGVPGHNGLPGQPGLTAELGSLPIEKHLLKSICGDCAQGQTAHPAFLLEKGEKGDQGIPGVPGFDNCARCFIERERPRAEEARGDNSEGEPGCSGSPGLPGPPGMPGQRGEEGPPGMRGSPGPPGPIGLQGERGLTGLTGDKGEPGPPGQPGYPGAMGPPGLPGIKGERGYTGPSGEKGESGPPGSEGLPGPQGPAGPRGERGPQGSSGEKGDQGFQGQPGFPGPPGPPGFPGKAGAPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSSGRPGAEGEPGAMGPQGRPGPPGHLGPPGQPGPPGLSTVGLKGDRGVPGERGLAGLPGQPGTPGHPGPPGEPGSDGAAGKEGPPGKQGLYGPPGPKGDPGPAGQKGQAGEKGRSGMPGGPGKSGSMGPIGPPGPAGERGHPGSPGPAGNPGLPGLPGSMGDMVNYDDIKRFIRQEIIKLFDERMAYYTSRMQFPMEVAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGMRGLPGTKGEKGDIGVGIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKSMKGPFG
InterPro domains: - IPR050149: Collagen superfamily (family) [1147-1553]
- IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [65-240]
- IPR008160: Collagen triple helix repeat (repeat) [375-1500]
- IPR048287: Thrombospondin-like, N-terminal domain (domain) [50-231]
Interaction partners: - Collagen alpha-1
- Collagen alpha-2
- Collagen alpha-1
- Collagen type V alpha 3 chain
- Collagen alpha-1
- Collagen alpha-2
- Collagen alpha-2
- Collagen alpha-1
- Collagen alpha-1
- Collagen alpha-1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0005488 (binding), GO:0005201 (extracellular matrix structural constituent), GO:0005515 (protein binding), GO:0050839 (cell adhesion molecule binding), GO:0005102 (signaling receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0009888 (tissue development), GO:0016043 (cellular component organization), GO:0061061 (muscle structure development), GO:0048513 (animal organ development), GO:0045229 (external encapsulating structure organization), GO:0007517 (muscle organ development), GO:0043062 (extracellular structure organization), GO:0060537 (muscle tissue development), GO:0007519 (skeletal muscle tissue development), GO:0030198 (extracellular matrix organization), GO:0060538 (skeletal muscle organ development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062023 (collagen-containing extracellular matrix)