wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: tRNA pseudouridine synthase A-like protein (Q387U9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MRRLSVSFLPFHLIVTTQRRQFGGNSKDGHKGEDKPIERVGGVPPTGPHPFNITSGAEGQISNQQRKAHDAITQLFRDDAQRKALYQKPGRTIGAQTTTAAISTPPNEDEFEGLQPISGDAEPSSITAVEAVEQELLDDAFLYFPPAQQSASGSVATTATNELYVPGQQIIPPGLTRYRVDVQYQGNDFDGWWKSTTRQLFRREVGLDGSITRVPVAEPGTIGNAAGVSRGETMGSRYHARTVLEEALAVALDVNTVRVVAGVIPEVGVSVRRLCCHVDVPSHIELQPRTVIQRATMWMEKRQQPLAILSYRRCKNQDFHARHSGLRRVYVYRILNRVAPPLFDAGLQWHVDRHLDVDRMKRFAKTLEGTKDFGYFADPKMANALRRAAMSPGGFSTGAVTEENFQPKATGESHRVTRGKAPKVTMEKGPSNLDRAAALPTFNEYGQRVVQPGAHGKEYYRVATNLPTVRTVDRLDVVRQDDEVLIWFVGRSFLRHQIRNMVSVLKAAGHGLWNDLELQQALQSGFEPSRHRFKRERFPTAPAYGLTLWDVEYPDQHRDDYVQFVDSGPYEQVNIARDI
InterPro domains: - IPR001406: Pseudouridine synthase I, TruA (family) [176-560]
- IPR020103: Pseudouridine synthase, catalytic domain superfamily (homologous_superfamily) [175-556]
- IPR020095: Pseudouridine synthase I, TruA, C-terminal (homologous_superfamily) [326-552]
- IPR020097: Pseudouridine synthase I, TruA, alpha/beta domain (domain) [466-554]
Interaction partners: - 30S Ribosomal protein S17, putative
- Methyltransferase
- Uncharacterized protein
- Rhodanese domain-containing protein
- PROP1-like PPR domain-containing protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
- Mitochondrial ribosomal protein S18
- Uncharacterized protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016853 (isomerase activity), GO:0016866 (intramolecular transferase activity), GO:0009982 (pseudouridine synthase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0043412 (macromolecule modification), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0009451 (RNA modification), GO:0034470 (ncRNA processing), GO:0006400 (tRNA modification), GO:0001522 (pseudouridine synthesis), GO:0034660 (ncRNA metabolic process), GO:0031119 (tRNA pseudouridine synthesis), GO:0006399 (tRNA metabolic process), GO:0008033 (tRNA processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0020023 (kinetoplast), GO:0005737 (cytoplasm), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Probable leucine-rich repeat receptor-like protein kinase At1g68400 (EC 2.7.11.1) (Q9M9C5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Sequence: MAKSSFFNKHLLLSLLILLQSCLLSSSSSTDSETLLNFKLTADSTGKLNSWNTTTNPCQWTGVSCNRNRVTRLVLEDINLTGSISSLTSLTSLRVLSLKHNNLSGPIPNLSNLTALKLLFLSNNQFSGNFPTSITSLTRLYRLDLSFNNFSGQIPPDLTDLTHLLTLRLESNRFSGQIPNINLSDLQDFNVSGNNFNGQIPNSLSQFPESVFTQNPSLCGAPLLKCTKLSSDPTKPGRPDEAKASPLNKPETVPSSPTSIHGGDKSNNTSRISTISLIAIILGDFIILSFVSLLLYYCFWRQYAVNKKKHSKILEGEKIVYSSNPYPTSTQNNNNQNQQVGDKGKMVFFEGTRRFELEDLLRASAEMLGKGGFGTAYKAVLEDGNEVAVKRLKDAVTVAGKKEFEQQMEVLGRLRHTNLVSLKAYYFAREEKLLVYDYMPNGSLFWLLHGNRGPGRTPLDWTTRLKIAAGAARGLAFIHGSCKTLKLTHGDIKSTNVLLDRSGNARVSDFGLSIFAPSQTVAKSNGYRAPELIDGRKHTQKSDVYSFGVLLLEILTGKCPNMVETGHSGGAVDLPRWVQSVVREEWTAEVFDLELMRYKDIEEEMVGLLQIAMACTAVAADHRPKMGHVVKLIEDIRGGGSEASPCNDGINSAVDSPCLSEDTCGGTTSQ
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [366-632]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [30-226]
- IPR013210: Leucine-rich repeat-containing N-terminal, plant-type (domain) [29-66]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [487-499]
- IPR001611: Leucine-rich repeat (repeat) [92-206]
- IPR017441: Protein kinase, ATP binding site (binding_site) [368-401]
- IPR000719: Protein kinase domain (domain) [362-636]
- IPR046959: Pollen receptor-like kinase 1-6/SFR4-like (family) [17-637]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0050793 (regulation of developmental process), GO:0051239 (regulation of multicellular organismal process), GO:2000241 (regulation of reproductive process), GO:0040008 (regulation of growth), GO:0050794 (regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0080092 (regulation of pollen tube growth), GO:0048638 (regulation of developmental growth), GO:0001558 (regulation of cell growth), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0051510 (regulation of unidimensional cell growth), GO:0022604 (regulation of cell morphogenesis), GO:0010769 (regulation of cell morphogenesis involved in differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0055044 (symplast), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0030312 (external encapsulating structure), GO:0009506 (plasmodesma), GO:0070161 (anchoring junction), GO:0005618 (cell wall), GO:0005886 (plasma membrane), GO:0009505 (plant-type cell wall), GO:0005911 (cell-cell junction)
Protein: Tripeptidyl-peptidase sed1 (EC 3.4.14.10) (Sedolisin-A) (Q70DX9)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Function: Secreted tripeptidyl-peptidase which degrades proteins at acidic pHs and is involved in virulence.
Subcellular location: Secreted, extracellular space {ECO:0000250}.
Sequence: MRLSHVLLGTAAAAGVLASPTPNDYVVHERRAVLPRSWTEEKRLDKASILPMRIGLTQSNLDRGHDLLMEISDPRSSRYGQHLSVEEVHSLFAPSQETVDRVRAWLESEGIAGDRISQSSNEQFLQFDASAAEVERLLGTEYYLYTHQGSGKSHIACREYHVPHSLQRHIDYITPGIKLLEVEGVKKARSIEKRSFRSPLPPILERLTLPLSELLGNTLLCDVAITPLCISALYNITRGSKATKGNELGIFEDLGDVYSQEDLNLFFSTFAQQIPQGTHPILKAVDGAQAPTSVTNAGPESDLDFQISYPIIWPQNSILFQTDDPNYTANYNFSGFLNTFLDAIDGSYCSEISPLDPPYPNPADGGYKGQLQCGVYQPPKVLSISYGGAEADLPIAYQRRQCAEWMKLGLQGVSVVVASGDSGVEGRNGDPTPTECLGTEGKVFAPDFPATCPYLTTVGGTYLPLGADPRKDEEVAVTSFPSGGGFSNIYERADYQQQAVEDYFSRADPGYPFYESVDNSSFAENGGIYNRIGRAYPDVAAIADNVVIFNKGMPTLIGGTSAAAPVFAAILTRINEERLAVGKSTVGFVNPVLYAHPEVFNDITQGSNPGCGMQGFSAATGWDPVTGLGTPNYPALLDLFMSLP
InterPro domains: - IPR036852: Peptidase S8/S53 domain superfamily (homologous_superfamily) [220-643]
- IPR050819: Tripeptidyl-peptidase I and related peptidases (family) [13-643]
- IPR030400: Sedolisin domain (domain) [224-643]
- IPR015366: Peptidase S53, activation domain (domain) [35-179]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0017171 (serine hydrolase activity), GO:0008233 (peptidase activity), GO:0008236 (serine-type peptidase activity), GO:0004175 (endopeptidase activity), GO:0004252 (serine-type endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0006508 (proteolysis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005618 (cell wall), GO:0009277 (fungal-type cell wall)
Protein: Uncharacterized protein YfcL (P64540)
Organism: Escherichia coli (strain K12)
Function: Not known
Sequence: MIAEFESRILALIDGMVDHASDDELFASGYLRGHLTLAIAELESGDDHSAQAVHTTVSQSLEKAIGAGELSPRDQALVTDMWENLFQQASQQ
InterPro domains: - IPR014987: Uncharacterised protein family YfcL (family) [4-86]
Interaction partners: - Elongation factor P lysine hydroxylase
- Probable membrane transporter protein YfcA
- Negative modulator of initiation of replication
- UPF0352 protein YejL
- Cell division protein ZapC
- Uncharacterized protein YheV
- Outer membrane protein assembly factor BamC
- Lipopolysaccharide export system protein LptC
- Penicillin-insensitive murein endopeptidase
- Chorismate synthase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0033554 (cellular response to stress), GO:0006259 (DNA metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0006974 (cellular response to DNA damage stimulus), GO:0006281 (DNA repair)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Retinol-binding protein 1 (Cellular retinol-binding protein) (CRBP) (Cellular retinol-binding protein I) (CRBP-I) (P02694)
Organism: Bos taurus (Bovine)
Function: Cytoplasmic retinol-binding protein. Accepts retinol from the transport protein STRA6, and thereby contributes to retinol uptake, storage and retinoid homeostasis.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q00915}. Lipid droplet {ECO:0000250|UniProtKB:Q00915}.
Sequence: MPVDFTGYWKMLANENFEEYLRALDVNVALRKIANLLKPDKEIVQEGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMTTVSWDGDKLECVQKGEKEGRGWTQWIEGDELHLEMRVEGVVCKQVFKKVN
InterPro domains: - IPR012674: Calycin (homologous_superfamily) [2-135]
- IPR000566: Lipocalin/cytosolic fatty-acid binding domain (domain) [6-133]
- IPR000463: Cytosolic fatty-acid binding (domain) [5-133]
- IPR031259: Intracellular lipid binding protein (family) [1-133]
- IPR031264: Retinol-binding protein 1 (family) [4-134]
Interaction partners: - Lecithin retinol acyltransferase
- Receptor for retinol uptake STRA6
- Retinol-binding protein 4
- Transthyretin
- Retinaldehyde-binding protein 1
- Retinol binding protein 1
- Retinol-binding protein 3
- Retinol dehydrogenase 5
- Short-chain dehydrogenase/reductase family 9C member 7
- Arginine--tRNA ligase, cytoplasmic
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:0008289 (lipid binding), GO:0019842 (vitamin binding), GO:0043178 (alcohol binding), GO:0019840 (isoprenoid binding), GO:0005501 (retinoid binding), GO:0019841 (retinol binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0042445 (hormone metabolic process), GO:0065008 (regulation of biological quality), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:0006066 (alcohol metabolic process), GO:0006629 (lipid metabolic process), GO:0010817 (regulation of hormone levels), GO:0120254 (olefinic compound metabolic process), GO:0042572 (retinol metabolic process), GO:0034308 (primary alcohol metabolic process), GO:0006720 (isoprenoid metabolic process), GO:0006721 (terpenoid metabolic process), GO:0016101 (diterpenoid metabolic process), GO:0001523 (retinoid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Transmembrane protein 150C (Tentonin 3) (B9EJG8)
Organism: Homo sapiens (Human)
Function: Component of a mechanosensitive cation channel. Confers mechanically activated (MA) currents with slow inactivation kinetics. May contribute to proprioception.
Subcellular location: Cell membrane {ECO:0000269|PubMed:25608530}; Multi-pass membrane protein {ECO:0000255}. Lysosome membrane {ECO:0000305|PubMed:25608530}; Multi-pass membrane protein {ECO:0000305}. Note=Localizes at the plasma membrane. A portion co-localizes with LAMP1 lysosomal marker (PubMed:25608530). {ECO:0000269|PubMed:25608530}.
Sequence: MDGKKCSVWMFLPLVFTLFTSAGLWIVYFIAVEDDKILPLNSAERKPGVKHAPYISIAGDDPPASCVFSQVMNMAAFLALVVAVLRFIQLKPKVLNPWLNISGLVALCLASFGMTLLGNFQLTNDEEIHNVGTSLTFGFGTLTCWIQAALTLKVNIKNEGRRVGIPRVILSASITLCVVLYFILMAQSIHMYAARVQWGLVMCFLSYFGTFAVEFRHYRYEIVCSEYQENFLSFSESLSEASEYQTDQV
InterPro domains: - IPR050911: DRAM/TMEM150 Autophagy Modulator (family) [10-241]
- IPR019402: Frag1/DRAM/Sfk1 (family) [9-217]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0003008 (system process), GO:0050877 (nervous system process), GO:0104004 (cellular response to environmental stimulus), GO:0009612 (response to mechanical stimulus), GO:0071496 (cellular response to external stimulus), GO:0071214 (cellular response to abiotic stimulus), GO:0050905 (neuromuscular process), GO:0071260 (cellular response to mechanical stimulus), GO:0007600 (sensory perception), GO:0050884 (neuromuscular process controlling posture)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Large ribosomal subunit protein uL23cz/uL23cy (50S ribosomal protein L23, chloroplastic) (P0C449)
Organism: Oryza sativa (Rice)
Function: Binds to 23S rRNA.
Subcellular location: Plastid, chloroplast.
Sequence: MDGIKYAVFTEKSLRLLGKNQYTFNVESGFTKTEIKHWVELFFGVKVVAVNSHRLPGKGRRMGPILGHTMHYRRMIITLQPGYSIPLLDREKN
InterPro domains: - IPR012678: Ribosomal protein uL23/eL15/eS24 core domain superfamily (homologous_superfamily) [1-89]
- IPR001014: Large ribosomal subunit protein uL23, conserved site (conserved_site) [73-88]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [1-90]
- IPR013025: Large ribosomal subunit protein uL23-like (family) [1-90]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009628 (response to abiotic stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0006950 (response to stress), GO:0009408 (response to heat), GO:0009266 (response to temperature stimulus), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0043933 (protein-containing complex organization), GO:0006996 (organelle organization), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0065003 (protein-containing complex assembly), GO:0042254 (ribosome biogenesis), GO:0022618 (ribonucleoprotein complex assembly), GO:0071826 (ribonucleoprotein complex subunit organization), GO:0042255 (ribosome assembly), GO:0140694 (non-membrane-bounded organelle assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0043231 (intracellular membrane-bounded organelle)
Protein: ADP-ribosylation factor-like protein 6 (Q5M9P8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Probably involved in membrane protein trafficking at the base of the ciliary organelle. May function in cilia biogenesis. Isoform 2 is required for proper retinal function and organization.
Subcellular location: Cell projection, cilium membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}.
Sequence: MGLFDKLAGWLGLKKKEVNVLCLGLDNSGKTTIINQLKPSNAQAQDIVPTIGFSIEKFKTSSLSFTVFDMSGQGRYRNLWEHYYKEGQAIIFVIDSGDKLRMVVAKEELDTLLNHPDIKHRRIPLLFFANKMDLRDALSAVKVSQLLCLENIKDKPWHICASDAVKGEGLLEGVDWLQDQIRAMKT
InterPro domains: - IPR041839: ADP-ribosylation factor-like protein 6 (family) [19-180]
- IPR024156: Small GTPase superfamily, ARF type (family) [14-179]
- IPR005225: Small GTP-binding domain (domain) [16-175]
- IPR006689: Small GTPase superfamily, ARF/SAR type (family) [1-181]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [14-186]
Interaction partners: - ADP-ribosylation factor-like 6 interacting protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0006996 (organelle organization), GO:0030030 (cell projection organization), GO:0022607 (cellular component assembly), GO:0044782 (cilium organization), GO:0070925 (organelle assembly), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0060271 (cilium assembly), GO:0120031 (plasma membrane bounded cell projection assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0005930 (axoneme), GO:0005737 (cytoplasm), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0099568 (cytoplasmic region), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0005929 (cilium), GO:0032838 (plasma membrane bounded cell projection cytoplasm), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0097014 (ciliary plasm)
Protein: AMP-activated protein kinase gamma 2 non-catalytic subunit (Q6V7V4)
Organism: Rattus norvegicus (Rat)
Function: Not known
Sequence: MLEKLEFQEEEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFMKQNLDELGIGTYHNIAFIHPNTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCSKLETLETIVDRIVRAEVHRLVVVNEADSIVGIISLSDILQALILTPAGAKQKETETE
InterPro domains: - IPR046342: CBS domain superfamily (homologous_superfamily) [3-314]
- IPR000644: CBS domain (domain) [32-319]
- IPR050511: AMP-activated protein kinase gamma/SDS23 families (family) [11-311]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0097367 (carbohydrate derivative binding), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0016740 (transferase activity), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:1901265 (nucleoside phosphate binding), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0043168 (anion binding), GO:0004672 (protein kinase activity), GO:0000166 (nucleotide binding), GO:0043169 (cation binding), GO:0019899 (enzyme binding), GO:0032553 (ribonucleotide binding), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity), GO:0016208 (AMP binding), GO:0019900 (kinase binding), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0032555 (purine ribonucleotide binding), GO:0017076 (purine nucleotide binding), GO:0032559 (adenyl ribonucleotide binding), GO:0004679 (AMP-activated protein kinase activity), GO:0019901 (protein kinase binding), GO:0030554 (adenyl nucleotide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0065009 (regulation of molecular function), GO:0050790 (regulation of catalytic activity)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0140535 (intracellular protein-containing complex), GO:0031588 (nucleotide-activated protein kinase complex), GO:1990234 (transferase complex), GO:0061695 (transferase complex, transferring phosphorus-containing groups), GO:1902911 (protein kinase complex)