Protein: ATP-dependent RNA helicase (A0A0R4IJV5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: RNA helicase
Subcellular location: Nucleus, nucleolus
Sequence: MDAFDLFRKLGSGAKFDLKRFAKDAERFKVGKSQSKDSSDQLSGIRYFGRETQEDTSLDSRPNEDDAEEGEASDEEQKQATESVKAARKKKKGAKRKSEDAEPETREGEGIQWMSLQNKTKEAKQESKDKPSLKRLKQLHNEKVNRIRHQNRINVHGTDIPDPVTTFEELQKEYDLDPRIIHNIQAAGFHTPTPIQMQAVPLMMHKREILACAPTGSGKTMAFCLPLLAHLRQPLNKGFRALIISPTRELATQTHRELLKLSEGVGFRVHMINKGVEAVKKYGPKSAKKFDILVTTPNRLIYLLNQDTPAINLSSVEWLVVDESDKLFEDGKTGFREQLATIFLACSSPNVRRVLFSATFATDVERWCKLNLDNLVSVSIGARNSAAETVEQQLLFVGSENGKILAMRNLIKQGFLPPVLVFVQSIDRARELYHELVYEGINVDVIHADRTQQQRDNVVSSFRSGKIWVLICTALLARGIDFKGINLVINYDFPTSAVEYIHRIGRTGRAGHKGKAVTFFTEDDKPLLRSIATVIKKAGCPVPDYMIGFKKIKSKLKHQLVTKPPRRAAIRTTPRMLFDRKLGKGKRKKRKATAKEAKGEAPEVISNC
InterPro domains: - IPR011545: DEAD/DEAH-box helicase domain (domain) [193-366]
- IPR001650: Helicase, C-terminal domain-like (domain) [389-550]
- IPR014014: RNA helicase, DEAD-box type, Q motif (domain) [169-197]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [141-552]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [188-393]
- IPR044764: DDX52/Rok1, DEAD-box helicase domain (domain) [180-381]
Interaction partners: - Something about silencing protein 10
- Nucleolar protein 6
- DDB1- and CUL4-associated factor 13
- Apoptosis-antagonizing transcription factor
- Small subunit processome component 20 homolog
- pre-rRNA processing protein FTSJ3
- rRNA-processing protein FCF1 homolog
- Probable RNA-binding protein 19
- U3 small nucleolar RNA-associated protein 25 homolog
- ATP-dependent RNA helicase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0097159 (organic cyclic compound binding), GO:0004386 (helicase activity), GO:0008186 (ATP-dependent activity, acting on RNA), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0140098 (catalytic activity, acting on RNA), GO:0003724 (RNA helicase activity), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0042254 (ribosome biogenesis), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0034470 (ncRNA processing), GO:0006364 (rRNA processing), GO:0034660 (ncRNA metabolic process), GO:0016072 (rRNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)