Protein: E3 ubiquitin-protein ligase TRIM33 isoform X1 (E7FDQ1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MFTAGPTGRSASPRPDLQKAVCGTCAACKGHLNDSTEPKLLPCLHTVCNTCLTKICTDGSSQDCPSCAQSFGLSEVTECAIFEDLSDNNKAPKCGGCEENEVSGWCVQCEEALCLDCVTAHHRVKVTRDHEVMPKKPPTGWIQRRRCPLHSQESLRFFCLVCEELTCKDCQLITHRGHSFVNQEEAVESQKQQMNSLLDSIRRQKGTISHSLLLLEARLQDIEHVKMLTKKLLIQSVHKIYHSMVLKASQILKDIQAVFAEEVRVLLERKSSLSRLEGCQDYIADFIDKIQRTQGHCLLVYKKRIETQVKMLLSRETCTPESMIKLHIEIQKDLCQHILNFGFVRITKNFVPFTSERTQYIQTNPVSVESLNPNSMETATNVGHAMASSSVNEQIPGDPATSSQTAPNHQILQSILQLSRSNQATTQPQPNHGTLFQPDLSNVRYSDSQSSCSSSPLSVQAQSHEVMSGQSKHAYSPSVHSQHHLPSSQQTKTKCNSKTAKRGNTWTLHYYSDMPNQTIPRIIQTPAPTHSIPASKKTPVQTHPNPTNNQILTPVHPMLAHNQTTIPVYPIQGNNQIPIASNNQTSIPTHPIPGSNQPLLLQQIPANTQSTLLTHAVLVNNLSPVVPYGLTANDQTLVQTQPILANNQTSVPTHAIPFNNQRKPLPQPITDNNKSLVLTHPIPNNNQTPVLMPPIQANNQAATLTHSVQFNNQTPGLTHPVSNIQSDVQTLIVAHPIQAGFLGAVHGFAAQPNVPLTILSTVNALPLNEVTAVSNVHSTGTSNDVMNHCPINSAFNVTPSGSSPHANPLCSDPISGSNRTNIPVKALADSACDQEAGMSSTSFTYADYSESNLPTSTVSDPRESSPLSPDLCFAVLDSLSTTTKKCVRQDKAGQSTTECDSGSKHWSADMPTTFRQLLETTCTPVNSIDSRNATTPVGSTPCGSSEDITGKSVSNGKTIQSCFDHSEGEKNEKESAATLKRFKTQLKEFRRSLCVSLVRLPVSLPPHGHPLPEFHLTTDSSTDHILVQESQGGEIKQVWRWHDGPVASRASSCSTSQMSDIDSSPASDVQFCVVCQSAGASLLCAKCGSAFHSDCHIPPIFTKPREDWVCLLCQDVSETLMIDSGEEMKTTGLSLQDQRRCEKLLLGLQCDENMGLLYSVTKNHSKTAEFDIILGRLQGNRKPPYRTAAELVSDVWTLFDILFIRSENKSLVVSLQQSFQQCLNQSFGTSLHASLLQHSSSTGAGETSQTDPLKQKHRNTLKRMREFFTTKSTIAVKKSCNDKGKKDTTAAKH
InterPro domains: - IPR011011: Zinc finger, FYVE/PHD-type (homologous_superfamily) [1066-1115]
- IPR001841: Zinc finger, RING-type (domain) [25-1113]
- IPR000315: B-box-type zinc finger (domain) [89-183]
- IPR019786: Zinc finger, PHD-type, conserved site (conserved_site) [1072-1113]
- IPR017907: Zinc finger, RING-type, conserved site (conserved_site) [43-52]
- IPR001965: Zinc finger, PHD-type (domain) [1071-1114]
- IPR047153: TRIM45/56/19-like (family) [24-555]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [19-1124]
- IPR019787: Zinc finger, PHD-finger (domain) [1069-1116]
Interaction partners: - E3 ubiquitin-protein ligase TRIM21
- Tripartite motif-containing 46b
- Adenosine deaminase RNA-specific B1b
- Tripartite motif-containing 109
- RNA helicase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0019222 (regulation of metabolic process), GO:0009607 (response to biotic stimulus), GO:0007389 (pattern specification process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0065009 (regulation of molecular function), GO:0051707 (response to other organism), GO:0009892 (negative regulation of metabolic process), GO:0035295 (tube development), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0043207 (response to external biotic stimulus), GO:0009888 (tissue development), GO:0003002 (regionalization), GO:0010646 (regulation of cell communication), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0051090 (regulation of DNA-binding transcription factor activity), GO:0009889 (regulation of biosynthetic process), GO:0009966 (regulation of signal transduction), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0009615 (response to virus), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0051607 (defense response to virus), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0009953 (dorsal/ventral pattern formation), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0051252 (regulation of RNA metabolic process), GO:0051253 (negative regulation of RNA metabolic process), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:2001141 (regulation of RNA biosynthetic process), GO:1902679 (negative regulation of RNA biosynthetic process), GO:1903507 (negative regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045892 (negative regulation of DNA-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)