Protein: Large ribosomal subunit protein uL16 (Q6ZWV3)
Organism: Mus musculus (Mouse)
Function: Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development (By similarity)
Subcellular location: Cytoplasm
Sequence: MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADEFEDMVAEKRLIPDGCGVKYIPNRGPLDKWRALHS
InterPro domains: - IPR001197: Large ribosomal subunit protein uL16, eukaryota/archaea (family) [1-214]
- IPR018255: Large ribosomal subunit protein uL16, conserved site, eukaryota/archaea (conserved_site) [108-129]
- IPR047873: Large ribosomal subunit protein uL16 (family) [12-165]
- IPR036920: Large ribosomal subunit protein uL16 superfamily (homologous_superfamily) [1-174]
- IPR016180: Large ribosomal subunit protein uL16 domain (domain) [41-165]
Interaction partners: - Large ribosomal subunit protein eL21
- Large ribosomal subunit protein uL2
- Large ribosomal subunit protein uL5
- Large ribosomal subunit protein uL14
- Large ribosomal subunit protein eL24
- Large ribosomal subunit protein eL13
- Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein
- Large ribosomal subunit protein eL30
- Large ribosomal subunit protein eL14
- Large ribosomal subunit protein uL18
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0003735 (structural constituent of ribosome)
Biological Process (BP): GO:0008150 (biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0019953 (sexual reproduction), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0051321 (meiotic cell cycle), GO:0022402 (cell cycle process), GO:0007049 (cell cycle), GO:0071840 (cellular component organization or biogenesis), GO:1903046 (meiotic cell cycle process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0061982 (meiosis I cell cycle process), GO:0007276 (gamete generation), GO:0140013 (meiotic nuclear division), GO:0044085 (cellular component biogenesis), GO:0016043 (cellular component organization), GO:0007140 (male meiotic nuclear division), GO:0007283 (spermatogenesis), GO:0007141 (male meiosis I), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0043933 (protein-containing complex organization), GO:0006996 (organelle organization), GO:0048232 (male gamete generation), GO:0007127 (meiosis I), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0042254 (ribosome biogenesis), GO:0022618 (ribonucleoprotein complex assembly), GO:0042273 (ribosomal large subunit biogenesis), GO:0065003 (protein-containing complex assembly), GO:0048285 (organelle fission), GO:0071826 (ribonucleoprotein complex subunit organization), GO:0042255 (ribosome assembly), GO:0000280 (nuclear division), GO:0140694 (non-membrane-bounded organelle assembly), GO:0000027 (ribosomal large subunit assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0030054 (cell junction), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0005790 (smooth endoplasmic reticulum), GO:0043231 (intracellular membrane-bounded organelle)