Protein: HAlF transporter (PGP related) (O45278)
Organism: Caenorhabditis elegans
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MHCLCVLRSTLCCQMPTSTYRMLLQTKAVPVQIIKRDLTAKVKNQKLNQNIRRVDRRNAAYLLRHTTWKDLVELYEIAKPFRKWIFLGTSFMVVSSGIFLIIPRILGKLIDQFDSNTGVQKAEEVFTMKIAKYFKEQPMSLVGLLAIGALATAAKVYCLQIAGVNIVGSLRKMVYSSIIRQDMTFFDKNMVGEIGSRHAADTVIVGYSVSSSLRAGVRAVLVGVGSIGMMLMTSLELSTVSFLTAPIVMGIFKMFGRVQQQCTWQLQEVAADVNQTAIERMANMKTIRMLSAEQQSIDEYCKKGELVLDISKTEALAKGSLIGSFQFTGYSAFSSILFYGSHLINTGHITYGELSSFCLYAVLAAASLSNISGFYNEVMKGLGASSRLLELKNAQPIMNLNSGIKKTDITTSIQFENVSFAYAGRKKTLENISFDIPRGKITAVIGPSGSGKSSIANLMLRLYDPADGRVTVDGVDLRDLNATTWRHAIGTVGQEPVLFTCSIRENILMGTEHPEKVSQYELEEAAQLANALDFIQGFENGFETMVGEHGCKLSGGQKQRIAIARALISKPKIMILDEATSALDATSDYLIRMTLDNLLKNHNLTVLVIAHRLATMQQADQVVYVNRGRIEGQGTFDEMMKIQNSIVEQEARRRGIPMNEQMSRVNTPVARGFSLKF
InterPro domains: - IPR017871: ABC transporter-like, conserved site (conserved_site) [553-567]
- IPR036640: ABC transporter type 1, transmembrane domain superfamily (homologous_superfamily) [31-410]
- IPR003593: AAA+ ATPase domain (domain) [438-629]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [406-649]
- IPR039421: Type 1 protein exporter (family) [65-647]
- IPR003439: ABC transporter-like, ATP-binding domain (domain) [413-652]
- IPR011527: ABC transporter type 1, transmembrane domain (domain) [85-380]
Interaction partners: - Ubiquitin-like protein 5
- Homeobox protein dve-1
- Stress activated transcription factor atfs-1
- Heat shock protein hsp-6
- ATP-dependent Clp protease proteolytic subunit 1, mitochondrial
- Chaperonin homolog Hsp-60, mitochondrial
- Ubiquitin-like protein
- AFG3-like protein spg-7
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0005215 (transporter activity), GO:0140657 (ATP-dependent activity), GO:0016887 (ATP hydrolysis activity), GO:0016787 (hydrolase activity), GO:0042626 (ATPase-coupled transmembrane transporter activity), GO:0022857 (transmembrane transporter activity), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0140359 (ABC-type transporter activity), GO:0042887 (amide transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0015399 (primary active transmembrane transporter activity), GO:1904680 (peptide transmembrane transporter activity), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity), GO:0035673 (oligopeptide transmembrane transporter activity), GO:0017111 (ribonucleoside triphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:1901700 (response to oxygen-containing compound), GO:0010035 (response to inorganic substance), GO:0006979 (response to oxidative stress), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0034599 (cellular response to oxidative stress), GO:0042542 (response to hydrogen peroxide), GO:1901701 (cellular response to oxygen-containing compound), GO:0000302 (response to reactive oxygen species), GO:0062197 (cellular response to chemical stress), GO:0034614 (cellular response to reactive oxygen species), GO:0070301 (cellular response to hydrogen peroxide)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005740 (mitochondrial envelope), GO:0019866 (organelle inner membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031966 (mitochondrial membrane), GO:0005743 (mitochondrial inner membrane)