Protein: Stromal cell-derived factor 1 (Q8AV10)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted
Sequence: MDLKVIVVVALMAVAIHAPISNAKPISLVERCWCRSTVNTVPQRSIRELKFLHTPNCPFQVIAKLKNNKEVCINPETKWLQQYLKNAINKMKKAQQQQV
InterPro domains: - IPR033899: CXC Chemokine domain (domain) [29-89]
- IPR039809: Chemokine beta/gamma/delta (family) [8-90]
- IPR036048: Chemokine interleukin-8-like superfamily (homologous_superfamily) [26-93]
- IPR001811: Chemokine interleukin-8-like domain (domain) [29-87]
Interaction partners: - Atypical chemokine receptor 3b
- C-X-C chemokine receptor type 4b
- C-C motif chemokine 21
- Chemokine (C-X-C motif) ligand 11, duplicate 5
- Chemokine (C-X-C motif) ligand 8a
- C-X-C chemokine receptor type 2
- C-X-C motif chemokine 19 precursor
- Stromal cell-derived factor 1
- C-C chemokine receptor type 9a
- C-C motif chemokine
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (signaling receptor activator activity), GO:0048018 (receptor ligand activity), GO:0042056 (chemoattractant activity)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0040011 (locomotion), GO:0042592 (homeostatic process), GO:0022414 (reproductive process), GO:0040007 (growth), GO:0048519 (negative regulation of biological process), GO:0009605 (response to external stimulus), GO:0019953 (sexual reproduction), GO:0048589 (developmental growth), GO:0048856 (anatomical structure development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0042221 (response to chemical), GO:0042330 (taxis), GO:0051240 (positive regulation of multicellular organismal process), GO:0071840 (cellular component organization or biogenesis), GO:0051239 (regulation of multicellular organismal process), GO:0045927 (positive regulation of growth), GO:0032504 (multicellular organism reproduction), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0050793 (regulation of developmental process), GO:0065008 (regulation of biological quality), GO:0019725 (cellular homeostasis), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0002683 (negative regulation of immune system process), GO:0040017 (positive regulation of locomotion), GO:0006885 (regulation of pH), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0040013 (negative regulation of locomotion), GO:0048523 (negative regulation of cellular process), GO:0040012 (regulation of locomotion), GO:0048869 (cellular developmental process), GO:0007275 (multicellular organism development), GO:0048584 (positive regulation of response to stimulus), GO:0002682 (regulation of immune system process), GO:0048878 (chemical homeostasis), GO:0030029 (actin filament-based process), GO:0051094 (positive regulation of developmental process), GO:0048609 (multicellular organismal reproductive process), GO:0048585 (negative regulation of response to stimulus), GO:0040008 (regulation of growth), GO:0048522 (positive regulation of cellular process), GO:0032989 (cellular component morphogenesis), GO:0032103 (positive regulation of response to external stimulus), GO:0044085 (cellular component biogenesis), GO:2000145 (regulation of cell motility), GO:0002685 (regulation of leukocyte migration), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0080134 (regulation of response to stress), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0002686 (negative regulation of leukocyte migration), GO:0032101 (regulation of response to external stimulus), GO:0000902 (cell morphogenesis), GO:0055082 (intracellular chemical homeostasis), GO:0009887 (animal organ morphogenesis), GO:0030900 (forebrain development), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0045595 (regulation of cell differentiation), GO:0016043 (cellular component organization), GO:0009790 (embryo development), GO:0042246 (tissue regeneration), GO:0051128 (regulation of cellular component organization), GO:0006935 (chemotaxis), GO:0051962 (positive regulation of nervous system development), GO:0010927 (cellular component assembly involved in morphogenesis), GO:0090066 (regulation of anatomical structure size), GO:0048638 (regulation of developmental growth), GO:0016477 (cell migration), GO:2000146 (negative regulation of cell motility), GO:0048639 (positive regulation of developmental growth), GO:0050801 (monoatomic ion homeostasis), GO:0007276 (gamete generation), GO:0045597 (positive regulation of cell differentiation), GO:0050920 (regulation of chemotaxis), GO:0008285 (negative regulation of cell population proliferation), GO:0001558 (regulation of cell growth), GO:0001945 (lymph vessel development), GO:0051130 (positive regulation of cellular component organization), GO:0030641 (regulation of cellular pH), GO:0030307 (positive regulation of cell growth), GO:0048857 (neural nucleus development), GO:0030036 (actin cytoskeleton organization), GO:2000147 (positive regulation of cell motility), GO:0061061 (muscle structure development), GO:0048598 (embryonic morphogenesis), GO:2000026 (regulation of multicellular organismal development), GO:0042127 (regulation of cell population proliferation), GO:0009888 (tissue development), GO:0050922 (negative regulation of chemotaxis), GO:0060322 (head development), GO:0036303 (lymph vessel morphogenesis), GO:0008354 (germ cell migration), GO:0001946 (lymphangiogenesis), GO:0050921 (positive regulation of chemotaxis), GO:0031099 (regeneration), GO:0032102 (negative regulation of response to external stimulus), GO:0031347 (regulation of defense response), GO:0032535 (regulation of cellular component size), GO:0030030 (cell projection organization), GO:0045773 (positive regulation of axon extension), GO:0048880 (sensory system development), GO:0097485 (neuron projection guidance), GO:0032990 (cell part morphogenesis), GO:0001944 (vasculature development), GO:0007369 (gastrulation), GO:0050769 (positive regulation of neurogenesis), GO:0030334 (regulation of cell migration), GO:1902622 (regulation of neutrophil migration), GO:0048666 (neuron development), GO:0031101 (fin regeneration), GO:0022607 (cellular component assembly), GO:0007420 (brain development), GO:0061387 (regulation of extent of cell growth), GO:0050927 (positive regulation of positive chemotaxis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0007399 (nervous system development), GO:0042692 (muscle cell differentiation), GO:0001764 (neuron migration), GO:0072359 (circulatory system development), GO:0030335 (positive regulation of cell migration), GO:0007417 (central nervous system development), GO:0002688 (regulation of leukocyte chemotaxis), GO:0048858 (cell projection morphogenesis), GO:0035701 (hematopoietic stem cell migration), GO:0050926 (regulation of positive chemotaxis), GO:0048882 (lateral line development), GO:0031344 (regulation of cell projection organization), GO:1903034 (regulation of response to wounding), GO:0051453 (regulation of intracellular pH), GO:0055001 (muscle cell development), GO:0060284 (regulation of cell development), GO:0010720 (positive regulation of cell development), GO:0051960 (regulation of nervous system development), GO:0006873 (intracellular monoatomic ion homeostasis), GO:0030239 (myofibril assembly), GO:0001667 (ameboidal-type cell migration), GO:0030336 (negative regulation of cell migration), GO:0022008 (neurogenesis), GO:0050770 (regulation of axonogenesis), GO:0055080 (monoatomic cation homeostasis), GO:0050727 (regulation of inflammatory response), GO:0031346 (positive regulation of cell projection organization), GO:0002689 (negative regulation of leukocyte chemotaxis), GO:0030516 (regulation of axon extension), GO:0006996 (organelle organization), GO:0031032 (actomyosin structure organization), GO:0030182 (neuron differentiation), GO:0097435 (supramolecular fiber organization), GO:0048883 (neuromast primordium migration), GO:0048925 (lateral line system development), GO:0050772 (positive regulation of axonogenesis), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0048920 (posterior lateral line neuromast primordium migration), GO:0030003 (intracellular monoatomic cation homeostasis), GO:0007010 (cytoskeleton organization), GO:0007411 (axon guidance), GO:0050767 (regulation of neurogenesis), GO:0048699 (generation of neurons), GO:0048916 (posterior lateral line development), GO:0070925 (organelle assembly), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0090022 (regulation of neutrophil chemotaxis), GO:0042074 (cell migration involved in gastrulation), GO:0050930 (induction of positive chemotaxis), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0120036 (plasma membrane bounded cell projection organization), GO:0071622 (regulation of granulocyte chemotaxis), GO:0008361 (regulation of cell size), GO:0051146 (striated muscle cell differentiation), GO:0031175 (neuron projection development), GO:0055002 (striated muscle cell development), GO:0048841 (regulation of axon extension involved in axon guidance), GO:0048881 (mechanosensory lateral line system development), GO:0048812 (neuron projection morphogenesis), GO:0061564 (axon development), GO:0031290 (retinal ganglion cell axon guidance), GO:0007409 (axonogenesis), GO:0010975 (regulation of neuron projection development), GO:0048915 (posterior lateral line system development), GO:0140694 (non-membrane-bounded organelle assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)