Protein: Transcription activator MSS11 (Q59N20)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Transcription factor that regulates pseudohyphal differentiation, invasive growth, floculation, adhesion and starch metabolism in response to nutrient availability
Subcellular location: Cytoplasm. Nucleus
Sequence: MSKPPPQHQSKNANNSLSSPVSDKQSNDSRQLLLAHLYNYFKTNGLEETAQALLIECNNTIPKATTNSKGYSLDNSGPDQKDTFLDQWWGLLWSIQSSINPNLNQMTNPSGILTPQHQMIVQQRMLQQQQQQAQQQQQQAQQQQAQQQQQQQQLLQQQRLQQQAMIQQQHQQQLINNLSARQQQVGLSTTTNQMGPPGSNSNNLQSNMSPNNEQLQSQARLQQLKLQFQQQQQQQLQQQQQQLQLQQQQQQQQQQQQQQQQQQQQQQRQQQRQRQKKFQRQLSTSSQKSPVINNGQPQQQLQQDQRPASAPQNQPTPGNNNNNNNNTNAVSPKLHRQSVDDYQMNLLQMENQNNSQRQKYLNNQQTRNSQQQQQQQQSQSQSQQSSPFQPPAQQPKNSTTTSTNTTTSRAQKSSRKQQPKNSRRQSVQQQQQQQPQQQPQQSQQMSTSSQSFTAANNSNNVNNTFDISPQIQDQGMLSTKEQQQQPQQPQPQPQSQPQSQSQSLPSNNNNNNNNKQDVVNVVFDDAFFSGNLLLDDFNEFANSTSNNGNGNGNNDMNSQFNNTQTERIMFSMPPNQNQNQFPSQSGDGGGGGGGSMQPNFFEGIELGDGNNSGNGDDDDAPIITTDWLSSMGSGPGYE
InterPro domains: - IPR006594: LIS1 homology motif (conserved_site) [29-61]
Interaction partners: - Transcriptional regulator of filamentous growth FLO8
- Morphogenetic regulator of filamentous growth protein 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0009628 (response to abiotic stimulus), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0045927 (positive regulation of growth), GO:0009892 (negative regulation of metabolic process), GO:0044237 (cellular metabolic process), GO:0048522 (positive regulation of cellular process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0048523 (negative regulation of cellular process), GO:0040008 (regulation of growth), GO:0044238 (primary metabolic process), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0010570 (regulation of filamentous growth), GO:0060255 (regulation of macromolecule metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0043170 (macromolecule metabolic process), GO:0010033 (response to organic substance), GO:0009891 (positive regulation of biosynthetic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0016043 (cellular component organization), GO:0009890 (negative regulation of biosynthetic process), GO:0090033 (positive regulation of filamentous growth), GO:0080090 (regulation of primary metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0071310 (cellular response to organic substance), GO:0010037 (response to carbon dioxide), GO:1900428 (regulation of filamentous growth of a population of unicellular organisms), GO:0010468 (regulation of gene expression), GO:0022607 (cellular component assembly), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:1900430 (positive regulation of filamentous growth of a population of unicellular organisms), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0051252 (regulation of RNA metabolic process), GO:0043933 (protein-containing complex organization), GO:0051253 (negative regulation of RNA metabolic process), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0065003 (protein-containing complex assembly), GO:0071824 (protein-DNA complex subunit organization), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1902680 (positive regulation of RNA biosynthetic process), GO:1902679 (negative regulation of RNA biosynthetic process), GO:0006357 (regulation of transcription by RNA polymerase II), GO:0045893 (positive regulation of DNA-templated transcription), GO:0006352 (DNA-templated transcription initiation), GO:2000142 (regulation of DNA-templated transcription initiation), GO:0045892 (negative regulation of DNA-templated transcription), GO:1903507 (negative regulation of nucleic acid-templated transcription), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0065004 (protein-DNA complex assembly), GO:2000144 (positive regulation of DNA-templated transcription initiation), GO:0045944 (positive regulation of transcription by RNA polymerase II), GO:0006367 (transcription initiation at RNA polymerase II promoter), GO:0000122 (negative regulation of transcription by RNA polymerase II), GO:0060260 (regulation of transcription initiation by RNA polymerase II), GO:0070897 (transcription preinitiation complex assembly), GO:0009268 (response to pH), GO:0060261 (positive regulation of transcription initiation by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)