Protein: N-glycosylation protein EOS1 (ER-localized and oxidants sensitive protein 1) (P53938)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in oxidative stress resistance and N-glycosylation.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:10649453, ECO:0000269|PubMed:17187761}; Multi-pass membrane protein {ECO:0000269|PubMed:10649453, ECO:0000269|PubMed:17187761}.
Sequence: MTWILSTGMGPHEDKYAKHERATFKKTYSSMKTLSLNHLTAKQHMLMALCRDISLLPPLTYIFTSLRKAWRVSMRTSITLYEPQSLRDAFTYFWQKLNSAYDNNSSFEGASQKAVNGDGKDSLLLSALTTARASEYLLCSLWCLVSLYLSYAILDSLMVRWIVKYSTVAAILRMFSMSLIIVTLELLLLSSLSPELDYFLHTWILISCVLTAVYIWQSYLTSDLRYIRNQEGEVQEDTNVPEETEDYEDGEDDADEDSHVVVADESTVDVPSNDSLSDNSDGGLFPVNRPSVSHSQSPKRPKKYPKKAFNFTTKRTIDLYKITVLCVVPVGLASFITMLGLLRNLFIQRLDVEQLERILHEMHPPA
InterPro domains: - IPR021100: N-glycosylation protein EOS1 (family) [18-362]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0022414 (reproductive process), GO:0000003 (reproduction), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0042221 (response to chemical), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0003006 (developmental process involved in reproduction), GO:0044237 (cellular metabolic process), GO:0071554 (cell wall organization or biogenesis), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0044238 (primary metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0019538 (protein metabolic process), GO:0019637 (organophosphate metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0010033 (response to organic substance), GO:1901135 (carbohydrate derivative metabolic process), GO:0006793 (phosphorus metabolic process), GO:0071852 (fungal-type cell wall organization or biogenesis), GO:1901360 (organic cyclic compound metabolic process), GO:0006629 (lipid metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0035966 (response to topologically incorrect protein), GO:0044260 (cellular macromolecule metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:0097305 (response to alcohol), GO:1901362 (organic cyclic compound biosynthetic process), GO:0006753 (nucleoside phosphate metabolic process), GO:0071310 (cellular response to organic substance), GO:0019438 (aromatic compound biosynthetic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0072521 (purine-containing compound metabolic process), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0036211 (protein modification process), GO:0034976 (response to endoplasmic reticulum stress), GO:0035967 (cellular response to topologically incorrect protein), GO:0043412 (macromolecule modification), GO:0090304 (nucleic acid metabolic process), GO:0015031 (protein transport), GO:0018130 (heterocycle biosynthetic process), GO:0006643 (membrane lipid metabolic process), GO:0090407 (organophosphate biosynthetic process), GO:0006259 (DNA metabolic process), GO:1903509 (liposaccharide metabolic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0006986 (response to unfolded protein), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0046467 (membrane lipid biosynthetic process), GO:0042157 (lipoprotein metabolic process), GO:0008610 (lipid biosynthetic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0051784 (negative regulation of nuclear division), GO:0045471 (response to ethanol), GO:0046474 (glycerophospholipid biosynthetic process), GO:0034620 (cellular response to unfolded protein), GO:0006281 (DNA repair), GO:0042158 (lipoprotein biosynthetic process), GO:0006650 (glycerophospholipid metabolic process), GO:0006497 (protein lipidation), GO:0008654 (phospholipid biosynthetic process), GO:0006664 (glycolipid metabolic process), GO:0009247 (glycolipid biosynthetic process), GO:0006506 (GPI anchor biosynthetic process), GO:0006505 (GPI anchor metabolic process), GO:0046488 (phosphatidylinositol metabolic process), GO:0032200 (telomere organization), GO:0000731 (DNA synthesis involved in DNA repair), GO:0006661 (phosphatidylinositol biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)