Protein: EPM2A-interacting protein 1 (Laforin-interacting protein) (Q7L775)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Endoplasmic reticulum {ECO:0000269|PubMed:12782127}.
Sequence: MWMTPKRSKMEVDEALVFRPEWTQRYLVVEPPEGDGALCLVCRRLIVATRERDVRRHYEAEHEYYERYVADGERAALVERLRQGDLPVASFTPEERAARAGLGLCRLLALKGRGWGEGDFVYQCMEVLLREVLPEHVSVLQGVDLSPDITRQRILSIDRNLRNQLFNRARDFKAYSLALDDQAFVAYENYLLVFIRGVGPELEVQEDLLTIINLTHHFSVGALMSAILESLQTAGLSLQRMVGLTTTHTLRMIGENSGLVSYMREKAVSPNCWNVIHYSGFLHLELLSSYDVDVNQIINTISEWIVLIKTRGVRRPEFQTLLTESESEHGERVNGRCLNNWLRRGKTLKLIFSLRKEMEAFLVSVGATTVHFSDKQWLCDFGFLVDIMEHLRELSEELRVSKVFAAAAFDHICTFEVKLNLFQRHIEEKNLTDFPALREVVDELKQQNKEDEKIFDPDRYQMVICRLQKEFERHFKDLRFIKKDLELFSNPFNFKPEYAPISVRVELTKLQANTNLWNEYRIKDLGQFYAGLSAESYPIIKGVACKVASLFDSNQICEKAFSYLTRNQHTLSQPLTDEHLQALFRVATTEMEPGWDDLVRERNESNP
InterPro domains: - IPR040647: SPIN-DOC-like, zinc-finger (domain) [21-76]
Interaction partners: - Laforin
- E3 ubiquitin-protein ligase CCNB1IP1
- E3 ubiquitin-protein ligase NHLRC1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0071704 (organic substance metabolic process), GO:0009719 (response to endogenous stimulus), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0051716 (cellular response to stimulus), GO:1901698 (response to nitrogen compound), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0046483 (heterocycle metabolic process), GO:0071495 (cellular response to endogenous stimulus), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0043170 (macromolecule metabolic process), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0043434 (response to peptide hormone), GO:1901652 (response to peptide), GO:0071417 (cellular response to organonitrogen compound), GO:0032870 (cellular response to hormone stimulus), GO:0010243 (response to organonitrogen compound), GO:0090304 (nucleic acid metabolic process), GO:0071310 (cellular response to organic substance), GO:1901699 (cellular response to nitrogen compound), GO:0010628 (positive regulation of gene expression), GO:0010467 (gene expression), GO:0010468 (regulation of gene expression), GO:1901653 (cellular response to peptide), GO:0071375 (cellular response to peptide hormone stimulus), GO:0032868 (response to insulin), GO:0032869 (cellular response to insulin stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)