Protein: carnitine O-palmitoyltransferase (A0A8M1N9G1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Mitochondrion outer membrane; Multi-pass membrane protein
Sequence: MAEAHQAVAFQFTVGPDGIDLQLSHEALRQVYLSGIHSWKKKFIRFKNGILNGVYPGSAPGFVLVLAGYLGRAQYLKVDPSLGLLFKLGNYVPISRYMSEQKQMLVGGVMVGTGLWIAIIFGMRTVLKGLLSWHGWMFASHGRMTWKIRLWLVFVKVFSGMQTPMLYSFQNSLPHLFVPSVKETTRRYLESVQPLLSDEEHQRMQRLALDFERNLGPKLQWYLKLKSWWATNYVSDWWEEYIYLRGRGPIMVNSNYYVMDFLYAFPTNIQAARAGNVIHAIMLYRRKLDRAQIKPVFALSNSVPLCSAQWERLFNTSRIPGKERDSVQHVSDSRHIVVYHRGRYFKVWMFYDGRLLLPREIEQQMERILADTSEPQPGEETLAALTAGDRVPWACARNAYLRHGTNKKSLDSVEKAAFFVTLDDTEQRFDQKNPVESLDRYAKSLLHGKCYDRWFDKSINLIIFKNGTMGLNAEHSWADAPIVGHLWEQVLSMDPVKLGYTEDGHCKGEPHANLPGPQRLQWNIPTECQTMITNSLSVAEALADDVDSHIIPFSDFGKGLIKKCRTSPDAFIQLALQLAHYRDKGKFCLTYEASMTRLFREGRTETVRSCTTESCAFVRAMNSNHTREQKLQLLKNAAEKHQQMYRLAMTGHGIDRHLFCLYVVLKYLGQDSPFLKEVLSEPWRLSTSQTPLQQGELFDLVKNPEYVTSGGGFGPVADDGYGVAYVIVGEKLINFHISSKRSSPETDSHRFGNNIRRAMIDMLDLFQLDKKDPK
InterPro domains: - IPR032476: Carnitine O-palmitoyltransferase, N-terminal (domain) [1-47]
- IPR039551: Choline/carnitine acyltransferase domain (domain) [178-756]
- IPR023213: Chloramphenicol acetyltransferase-like domain superfamily (homologous_superfamily) [173-762]
- IPR042231: Choline/Carnitine o-acyltransferase, domain 2 (homologous_superfamily) [232-549]
- IPR000542: Acyltransferase ChoActase/COT/CPT (family) [149-766]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0008374 (O-acyltransferase activity), GO:0016409 (palmitoyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009894 (regulation of catabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0001945 (lymph vessel development), GO:0080090 (regulation of primary metabolic process), GO:0048731 (system development), GO:0062012 (regulation of small molecule metabolic process), GO:0050994 (regulation of lipid catabolic process), GO:0010565 (regulation of cellular ketone metabolic process), GO:0031329 (regulation of cellular catabolic process), GO:0019216 (regulation of lipid metabolic process), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0031998 (regulation of fatty acid beta-oxidation), GO:0019217 (regulation of fatty acid metabolic process), GO:0046320 (regulation of fatty acid oxidation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0019867 (outer membrane), GO:0043227 (membrane-bounded organelle), GO:0005740 (mitochondrial envelope), GO:0031968 (organelle outer membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0031966 (mitochondrial membrane), GO:0005741 (mitochondrial outer membrane)