wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Mu-type opioid receptor (B8JHS2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Cell projection, axon {ECO:0000256|ARBA:ARBA00004489}. Cell projection, dendrite {ECO:0000256|ARBA:ARBA00004279}. Endosome {ECO:0000256|ARBA:ARBA00004177}. Perikaryon {ECO:0000256|ARBA:ARBA00004484}.
Sequence: MMENTGNISDLLYALSNPMVSNSSIFCRNFSNSSGLVNMNSSVCDRTPELDKSSTPVIVAIIITALYSIVCVMGLVGNVLVMYVIIRYTKMKTATNIYIFNLALADSLATSTLPFQSVNYLMGTWPFGDELCKIVMSIDYYNMFTSIFTLTTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMVMASTTSDLHSNGIIDCTLLFPHPSWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIFVIIKALVTIPNSLLQTITWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCVPSPSVLDLQNSTRSRNPQRDGQSSGHTVDRTNQQV
InterPro domains: - IPR000105: Mu opioid receptor (family) [298-382]
- IPR001418: Opioid receptor (family) [87-342]
- IPR017452: GPCR, rhodopsin-like, 7TM (domain) [77-331]
- IPR000276: G protein-coupled receptor, rhodopsin-like (family) [62-339]
Interaction partners: - Pro-opiomelanocortin protein
- Proenkephalin a
- Prodynorphin.
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0033218 (amide binding), GO:0042277 (peptide binding), GO:0004888 (transmembrane signaling receptor activity), GO:0001653 (peptide receptor activity), GO:0042923 (neuropeptide binding), GO:0008528 (G protein-coupled peptide receptor activity), GO:0004930 (G protein-coupled receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007186 (G protein-coupled receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: WbnF (O51400)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Function: Not known
Sequence: MKIFLTGIAGFIGFHVAKKLVEKGHEVLGIDVLNDYYELKFKHERLEALGFCSKDVKTHKIIKSEKYNNLSFAYLDILNKDKLLELFKDHKFTHVCHLAAQAGIRDSLENPDSYVSINIVGFFNVLDVCRVYKENIEHFVYASTSSVYGINENMPSSEDSITDHPLNLYAASKKSNEMMAHAYSASFNIPTTGLRFFTVYGTYGRPDMALYLFSDGIKNGKAINIFNNGNMARDFTYVGDIADGVYKVLKNPAKSDCNFDVKNPNSSTSSFPYRIYNIGTGHATKLLDFISELEANFDKKALKNYMPMQKADVVESCCDILKLKNDVGYEAKVSIKEGIKEFSQWYKMLESTKKT
InterPro domains: - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [1-347]
- IPR001509: NAD-dependent epimerase/dehydratase (domain) [3-257]
Interaction partners: - Small ribosomal subunit protein uS8
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS17
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS12
- Small ribosomal subunit protein uS19
- Small ribosomal subunit protein uS2
- Large ribosomal subunit protein uL4
- Small ribosomal subunit protein uS14
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016835 (carbon-oxygen lyase activity), GO:0016836 (hydro-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0006793 (phosphorus metabolic process), GO:0009225 (nucleotide-sugar metabolic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0019438 (aromatic compound biosynthetic process), GO:0018130 (heterocycle biosynthetic process), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0009226 (nucleotide-sugar biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Merozoite surface protein 7 (Q8IDX8)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Not known
Sequence: MKSNIIFYFSFFFVYLYYVSCNQSTHSTPVNNEEDQEELYIKNKKLEKLKNIVSGDFVGNYKNNEELLNKKIEELQNSKEKNVHVLINGNSIIDEIEKNEENDDNEENNDDDNTYELDMNDDTFLGQNNDSHFENVDDDAVENEQEDENKEKSESFPLFQNLGLFGKNVLSKVKAQSETDTQSKNEQEISTQGQEVQKPAQGGESTFQKDLDKKLYNLGDVFNHVVDISNKKNKINLDEYGKKYTDFKKEYEDFVLNSKEYDIIKNLIIMFGQEDNKSKNGKTDIVSEAKHMTEIFIKLFKDKEYHEQFKNYIYGVYSYAKQNSHLSEKKIKPEEEYKKFLEYSFNLLNTM
InterPro domains: - IPR024781: Merozoite surface protein, C-terminal (domain) [217-346]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0044403 (biological process involved in symbiotic interaction), GO:0051701 (biological process involved in interaction with host), GO:0044000 (movement in host), GO:0044409 (entry into host)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0043226 (organelle), GO:0005576 (extracellular region), GO:0043657 (host cell), GO:0043227 (membrane-bounded organelle), GO:0033643 (host cell part), GO:0043230 (extracellular organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0020003 (symbiont-containing vacuole), GO:0030430 (host cell cytoplasm), GO:0033655 (host cell cytoplasm part)
Protein: Protein SSP120 (P39931)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Not known
Sequence: MRFLRGFVFSLAFTLYKVTATAEIGSEINVENEAPPDGLSWEEWHMDHEHQLKDYTPETFFALHDIKKKGFLDENDILSLYGLNREEIVGAGDGMGQHDESEKIDNEMAKRVVSLIMRLLDVDDNTKITKEEYLQFAKRGNKFPDLGVGVGHHSDFELEYEIHHWNKFHKDKDPDVKVVHKEDIEHELLHHEHEIEHEEEIQRGASRATVITDDELESRIELKNIPEKFKNGIF
InterPro domains: - IPR011992: EF-hand domain pair (homologous_superfamily) [41-139]
- IPR002048: EF-hand domain (domain) [108-143]
- IPR040250: Nucleobindin (family) [37-201]
Interaction partners: - Protein EMP47
- Endoplasmic reticulum transmembrane protein 3
- Peptidyl-prolyl cis-trans isomerase FPR2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0005509 (calcium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044248 (cellular catabolic process), GO:0019538 (protein metabolic process), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0009057 (macromolecule catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0006508 (proteolysis), GO:0044265 (cellular macromolecule catabolic process), GO:0030163 (protein catabolic process), GO:0043632 (modification-dependent macromolecule catabolic process), GO:0010498 (proteasomal protein catabolic process), GO:0051603 (proteolysis involved in protein catabolic process), GO:0019941 (modification-dependent protein catabolic process), GO:0043161 (proteasome-mediated ubiquitin-dependent protein catabolic process), GO:0006511 (ubiquitin-dependent protein catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: 32 kDa beta-galactoside-binding lectin lec-3 (32 kDa GBP) (Q09581)
Organism: Caenorhabditis elegans
Function: Binds galactose.
Sequence: MAEPKSFNIPYRSKLTERIEPGQTLIIRGKTIDESKRFNINLHKDSPDFSGNDVPLHLSIRFDEGKIVYNAYTKGTWGKEERAKNPIKKGDDFDIRIRAHDSKFQVSINHKEVKNFEHRIPLNSVSHLSIDGDVVLNHVQWGGKYYPVPYESGIAADGLVPGKTLVVYGTPEKKAKKFNINLLKKNGDIALHFNPRFDEKANGFMCAKPTPGSVVRNSLVNGEWGNEEREGKNPFERLTAFDLEIRNEEFAFQIFVNGERFASYAHRVDPHDIAGLQIQGDIELTGIQVVNNQPAQE
InterPro domains: - IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [7-292]
- IPR001079: Galectin, carbohydrate recognition domain (domain) [9-290]
- IPR044156: Galectin-like (family) [84-289]
Interaction partners: - N-acyl-aliphatic-L-amino acid amidohydrolase
- DUF1080 domain-containing protein
- RRM domain-containing protein
- RRM domain-containing protein
- Galectin
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0040017 (positive regulation of locomotion), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0051239 (regulation of multicellular organismal process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0040012 (regulation of locomotion), GO:0048522 (positive regulation of cellular process), GO:0010171 (body morphogenesis), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:2000145 (regulation of cell motility), GO:0035556 (intracellular signal transduction), GO:0050920 (regulation of chemotaxis), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009790 (embryo development), GO:0048608 (reproductive structure development), GO:0045137 (development of primary sexual characteristics), GO:0007548 (sex differentiation), GO:2000147 (positive regulation of cell motility), GO:0016477 (cell migration), GO:0061458 (reproductive system development), GO:0010172 (embryonic body morphogenesis), GO:0008406 (gonad development), GO:0030335 (positive regulation of cell migration), GO:0030334 (regulation of cell migration), GO:0001667 (ameboidal-type cell migration), GO:1903354 (regulation of distal tip cell migration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: 5-methylthioadenosine/S-adenosylhomocysteine deaminase (MTA/SAH deaminase) (EC 3.5.4.28) (EC 3.5.4.31) (Q72B14)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
Sequence: MPLPCDTILQAALIVTQDDARTVIEDGAIAIHEGRIAAVGQRDAIVGNWHGVTVIDMGESLIMPGLVNAHTHASMTLLRGLADDLPLMDWLTGHIFPVEKGLTGELVELGALLGCAEMLRTGTTAFSDMYLIEDATLRAVDRAGLRCLAGEAIFAFPSPAYADPETAFDLVRAQHDRWKHHARAALAVAPHAVYTSTPAILARCRDLAEELGLPIHLHLAETATETAQCIEQHGARPVPYCDGLGLLTPRTTLAHCVDLTEGEIDLLAERGVTVAHCPESNMKLASGIAPATAMLGRGMTLGLGTDGAASNNSLNMFTEMTSCALLHKVHHMDPTCAPASAVLDMATRGGAHALHMQGIGRIEAGCPADIIALDLRAPNMQPIFNPASHLVYAATGHETRLTMVGGEVLYLDGCYTRFDMDDLLKEVRKARTWAMEQVRAAR
InterPro domains: - IPR011059: Metal-dependent hydrolase, composite domain superfamily (homologous_superfamily) [6-433]
- IPR050287: 5-Methylthioadenosine/S-adenosylhomocysteine deaminase (family) [3-432]
- IPR006680: Amidohydrolase-related (domain) [62-408]
- IPR032466: Metal-dependent hydrolase (homologous_superfamily) [64-359]
- IPR023512: Deaminase MtaD/DadD (family) [6-435]
Interaction partners: - Purine nucleoside phosphorylase
- SPFH domain/Band 7 family protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0008380 (RNA splicing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: STAS domain-containing protein (Q5B9Q0)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MPGDIPTKVGHGLAKVLRLKLPEKPQPDAVTRGESTFSVGTFDTYSYVEPEPTAAEWFAEITPSWKEIGLYFYRLFPFLSWITRYNTTWLIGDLVAGITVGAVVVPQGMAYAQLAQLPVEYGLYSSFMGVLIYWFFATSKDITIGPVAVMSTLVGNIVTEAAETLPDVEPHVIASCLAVICGGIVTFMGLARLGFIVDFIPLPAITAFMTGSAINICSGQVSTMLGETDKVNTRGATYNTIIQTLRALPSSTLDAAMGVTACAMLYIIRFACNTAAKKQPHRAKMWFFISTLRTVFVILFYTMISAATNLHRRDNPAFKVLGTVPRGFKHAAVPTVNAEIIKTFASELPAAVIVLLIEHIAISKSFGRVNNYTIDPSQELVAIGVTNLLGPFLGGYPATGSFSRTAIKSKAGVRTPLAGVITAVVVLLAIYALPALFWYIPKASLAGVIIHAVGDLITPPNVVYQFYRVSPLDCVIFFVGVIVTVFTSIEIGVYCTVCISVAVLLFRVAKARGEFLGRVTIHSVVGDHVLEESKPGLGDADRTRSIFLPLNHADGSNPEIEIEQPYPGIFIYRFSEGFNYPNANHYTDYLVETIFQKTRRTNPFTYSNPGDRPWNNPGPRKGKQEEDRSHLPTLRAVILDFSSVNNVDVTSVQNLIDVRNQLDIYASPHTVQWHFAHVKNRWTKRALAAAGFGYPTPQSEDGFHRWKPIFSVTEIEGQSSAAAHAEIVANENTRQASSHGHDLESGIKNPSHTAERETHGIEESSNSSIGEDDKLQRDLKDSKAYQNRRKMAVVQGVNLPFFHIDITSALESALANSQEEPADVSSD
InterPro domains: - IPR036513: STAS domain superfamily (homologous_superfamily) [559-703]
- IPR018045: Sulphate anion transporter, conserved site (conserved_site) [119-140]
- IPR011547: SLC26A/SulP transporter domain (domain) [90-479]
- IPR002645: STAS domain (domain) [566-692]
- IPR001902: SLC26A/SulP transporter (family) [66-703]
Interaction partners: - Sulfate transporter family protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901682 (sulfur compound transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015116 (sulfate transmembrane transporter activity), GO:0015103 (inorganic anion transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0098660 (inorganic ion transmembrane transport), GO:0006810 (transport), GO:0072348 (sulfur compound transport), GO:0071705 (nitrogen compound transport), GO:0098661 (inorganic anion transmembrane transport), GO:0015698 (inorganic anion transport), GO:0008272 (sulfate transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: GTPase IMAP family member 5 (Immunity-associated nucleotide 4 protein) (IAN-4) (Immunity-associated nucleotide 4-like 1 protein) (Q8K3L6)
Organism: Rattus norvegicus (Rat)
Function: Required for mitochondrial integrity and T-cell survival. May contribute to T-cell quiescence.
Subcellular location: Lysosome membrane {ECO:0000269|PubMed:28223986}; Single-pass type IV membrane protein {ECO:0000269|PubMed:28223986}. Endosome, multivesicular body membrane {ECO:0000269|PubMed:21487483}; Single-pass type IV membrane protein {ECO:0000305}. Endosome membrane {ECO:0000269|PubMed:28223986}; Single-pass type IV membrane protein {ECO:0000269|PubMed:28223986}.
Sequence: MEDHGFEELSTRTHDLNVRRLTKGNINFLLSTGQETYSVEDSGLLRILLVGKSGCGKSATGNSILRRPAFESRLRGQSVTRTSQAEMGTWEGRSFLVVDTPPIFESKIQNQDMDKDIGNCYLMCAPGPHVLLLVTQLGRYTVEDAMAVRMVKQIFGVGVMRYMIVLFTHKEDLADESLEEFVTHTGNLDLHRLVQECGRRYCAFNNKASGEEQQGQLAELMALVRRLEQEHEGSFHSNDLFVYTQVFLRGGYSEHQEPYKFYLTKVRQEVEKQKRELEEQEGSWMAKMLCRVTSCLDWHIAVSVLLIVLGLTLLITLINMYIGRWK
InterPro domains: - IPR045058: GTPase GIMA/IAN/Toc (family) [45-277]
- IPR006703: AIG1-type guanine nucleotide-binding (G) domain (domain) [42-245]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [37-288]
Interaction partners: - Histocompatibility 2, class II antigen E alpha
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0050794 (regulation of cellular process), GO:0042221 (response to chemical), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0010941 (regulation of cell death), GO:0035556 (intracellular signal transduction), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0034097 (response to cytokine), GO:0071310 (cellular response to organic substance), GO:0043067 (regulation of programmed cell death), GO:0019221 (cytokine-mediated signaling pathway), GO:0071345 (cellular response to cytokine stimulus), GO:0034612 (response to tumor necrosis factor), GO:0071356 (cellular response to tumor necrosis factor)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Chaperone protein DNAJ, putative (Q38DE1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MLRFTSVSSIWRRLAAAPPTAATAAFANVSKRQSSSNKDYYKILGVSQSASQSDIKKAYRKRALETHPDQGGNKEDFAEVAEAYECLSNEEKRRIYDQYGSEAAANMNAGGGMGGFGGRSAEDIFAEFFKGGMGGFGGNRSAGPPQVPPLEVTLRMTLEEVYKGASKSPRVNRPVVCSDCRGFGTKSQKKKPKCSECDGSGHVVQHHRFGPGMVQQTVSQCPRCGGAGTVAKPDDKCPKCKGMGYRHLVQSVSIDIPAGVPPDVTLVVRGEGGTMPEAEPGDLHVHVEVEEHNVFKRRGNDLVVERDVTLSEALLEFDLSLKTLDGRSITVKSPKSSVLQPNSVLRVAGEGMPNSSGGNGDLYIVTKLKLPRTLTDQQKEAVKKAFGEPKKKDPDSGSDKTVTASVLRGGVREMEEALHSNWDSERGGGSQQGNGRRRSGRKQHTAECVHQ
InterPro domains: - IPR001305: Heat shock protein DnaJ, cysteine-rich domain (domain) [164-249]
- IPR036410: Heat shock protein DnaJ, cysteine-rich domain superfamily (homologous_superfamily) [174-245]
- IPR008971: HSP40/DnaJ peptide-binding (homologous_superfamily) [149-381]
- IPR036869: Chaperone J-domain superfamily (homologous_superfamily) [35-141]
- IPR044713: DnaJ homolog subfamily A member 1/2-like (family) [38-395]
- IPR001623: DnaJ domain (domain) [38-111]
- IPR012724: Chaperone DnaJ (family) [36-414]
- IPR002939: Chaperone DnaJ, C-terminal (domain) [150-371]
- IPR018253: DnaJ domain, conserved site (conserved_site) [77-96]
Interaction partners: - Uncharacterized protein
- Heat shock protein, putative
- Chaperone protein DNAJ, putative
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0009628 (response to abiotic stimulus), GO:0019222 (regulation of metabolic process), GO:0006950 (response to stress), GO:0009408 (response to heat), GO:0009266 (response to temperature stimulus), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)