Protein: Wiskott-Aldrich syndrome protein family member (WASP family protein member) (F2FB81)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|RuleBase:RU367034}.
Sequence: MPLPKRSIEPVHVARSVYQQDELQSVELETVTNTTLTNIIRQLSSLSKHAEDVFGELARDVGNIGDRANSLQARIDRLAIKVTQLDSTVEEVPLTDITRKKAFKSAKVFDQQIFSRATMPAPMMDTYAQCDKPPPLDKLNVYRDDGKDGLKFYTDPNYFFELWRQEMLKDTERVMHDKGKKLNRPRQDGGAGGAAGRGNKKQKTKIRVPHNTREQQRQRALVHGETLMPNNVIYRTPNSMVNEEAGYGIQLVKIQTVGEADIDLRHSTLDAHHQVVGNIQDVDTVKPYNMLSHLENNSNVTKQTAVAIADMGVYDTRPPRPNSIELNRSYQSEQIDGSTYEQLPPQMGNQYAATFGNGMGGPQQMHMQHQQMYDAGMYQSHALYGQTGQGVMSPEPIYGPGTPSRNKPRPSQPPPAPPSNGSGGGTPTASNANTPTRGRSMSTSRDALPPPPPVPDVISPMSGMNGVNSGHMAAKLLGRANSSSGAGSPNSVQNANDMVMTQLSNTFHSIGMTGNQLNSLSDLPPPPPVPDQHSPKMSPPNAAPPPPPPPPPVEEGMGSGNQHTLRPHQILPKSLANGEMQQPGQQNGVPHIVAPKKMLPPFHDPRNDLMKAIRDGITLRKVEKSEQKEIERNAAPLDVASILARRVAIELSESEDSDSEDDSEGWMEPNETSA
InterPro domains: - IPR028288: SCAR/WAVE family (family) [1-180]
- IPR003124: WH2 domain (domain) [605-622]
Interaction partners: - Abelson interacting protein, isoform D
- FI14118p
- Cytoplasmic FMR1-interacting protein
- Membrane-associated protein Hem
- Insulin receptor substrate 53 kDa, isoform A
- Wiskott-Aldrich syndrome protein family member
- WASH complex subunit 1
- Actin-related protein 2
- Ras-related protein Rac1
- Cdc42-interacting protein 4, isoform B
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0040011 (locomotion), GO:0022414 (reproductive process), GO:0040007 (growth), GO:0009605 (response to external stimulus), GO:0019953 (sexual reproduction), GO:0048589 (developmental growth), GO:0048856 (anatomical structure development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0042221 (response to chemical), GO:0042330 (taxis), GO:0022402 (cell cycle process), GO:0071840 (cellular component organization or biogenesis), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0050793 (regulation of developmental process), GO:0016049 (cell growth), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0006949 (syncytium formation), GO:0050794 (regulation of cellular process), GO:0008037 (cell recognition), GO:0048869 (cellular developmental process), GO:0007275 (multicellular organism development), GO:0007300 (ovarian nurse cell to oocyte transport), GO:0007155 (cell adhesion), GO:0007049 (cell cycle), GO:0051234 (establishment of localization), GO:0140253 (cell-cell fusion), GO:0030029 (actin filament-based process), GO:0048609 (multicellular organismal reproductive process), GO:0048522 (positive regulation of cellular process), GO:0032989 (cellular component morphogenesis), GO:0033627 (cell adhesion mediated by integrin), GO:0008038 (neuron recognition), GO:0044085 (cellular component biogenesis), GO:0048468 (cell development), GO:0060560 (developmental growth involved in morphogenesis), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0032970 (regulation of actin filament-based process), GO:0044089 (positive regulation of cellular component biogenesis), GO:0044087 (regulation of cellular component biogenesis), GO:0000902 (cell morphogenesis), GO:0048588 (developmental cell growth), GO:0009887 (animal organ morphogenesis), GO:0000768 (syncytium formation by plasma membrane fusion), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0016043 (cellular component organization), GO:0051128 (regulation of cellular component organization), GO:0006935 (chemotaxis), GO:0016477 (cell migration), GO:0007276 (gamete generation), GO:0007281 (germ cell development), GO:0051130 (positive regulation of cellular component organization), GO:0030036 (actin cytoskeleton organization), GO:0061061 (muscle structure development), GO:0008335 (female germline ring canal stabilization), GO:0006810 (transport), GO:0030030 (cell projection organization), GO:0007520 (myoblast fusion), GO:0048880 (sensory system development), GO:0097485 (neuron projection guidance), GO:0032990 (cell part morphogenesis), GO:0090596 (sensory organ morphogenesis), GO:0032956 (regulation of actin cytoskeleton organization), GO:0060491 (regulation of cell projection assembly), GO:0048666 (neuron development), GO:0022607 (cellular component assembly), GO:1902903 (regulation of supramolecular fiber organization), GO:0000904 (cell morphogenesis involved in differentiation), GO:0007399 (nervous system development), GO:0001764 (neuron migration), GO:0042692 (muscle cell differentiation), GO:0007292 (female gamete generation), GO:1902905 (positive regulation of supramolecular fiber organization), GO:0120034 (positive regulation of plasma membrane bounded cell projection assembly), GO:0048858 (cell projection morphogenesis), GO:1990138 (neuron projection extension), GO:0007015 (actin filament organization), GO:0022604 (regulation of cell morphogenesis), GO:0007413 (axonal fasciculation), GO:0031344 (regulation of cell projection organization), GO:0007423 (sensory organ development), GO:0048477 (oogenesis), GO:0031532 (actin cytoskeleton reorganization), GO:0022008 (neurogenesis), GO:0030866 (cortical actin cytoskeleton organization), GO:0031346 (positive regulation of cell projection organization), GO:0033043 (regulation of organelle organization), GO:0006996 (organelle organization), GO:0031032 (actomyosin structure organization), GO:0010638 (positive regulation of organelle organization), GO:0030182 (neuron differentiation), GO:0097435 (supramolecular fiber organization), GO:0120032 (regulation of plasma membrane bounded cell projection assembly), GO:0051493 (regulation of cytoskeleton organization), GO:0051491 (positive regulation of filopodium assembly), GO:0048592 (eye morphogenesis), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:1902284 (neuron projection extension involved in neuron projection guidance), GO:0045010 (actin nucleation), GO:0150063 (visual system development), GO:0007010 (cytoskeleton organization), GO:0007411 (axon guidance), GO:0048699 (generation of neurons), GO:0010592 (positive regulation of lamellipodium assembly), GO:0048675 (axon extension), GO:0051127 (positive regulation of actin nucleation), GO:0008360 (regulation of cell shape), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0001654 (eye development), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0090527 (actin filament reorganization), GO:0051146 (striated muscle cell differentiation), GO:1902745 (positive regulation of lamellipodium organization), GO:0031175 (neuron projection development), GO:0110053 (regulation of actin filament organization), GO:0051495 (positive regulation of cytoskeleton organization), GO:0048812 (neuron projection morphogenesis), GO:0014902 (myotube differentiation), GO:0061564 (axon development), GO:1902743 (regulation of lamellipodium organization), GO:0010591 (regulation of lamellipodium assembly), GO:0007409 (axonogenesis), GO:0051125 (regulation of actin nucleation), GO:0048749 (compound eye development), GO:0051489 (regulation of filopodium assembly), GO:0001745 (compound eye morphogenesis), GO:0106030 (neuron projection fasciculation), GO:0034314 (Arp2/3 complex-mediated actin nucleation), GO:0030865 (cortical cytoskeleton organization), GO:0048846 (axon extension involved in axon guidance)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0045178 (basal part of cell), GO:0031209 (SCAR complex), GO:0045177 (apical part of cell), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)