wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: ADAM metallopeptidase domain 28 (A0A8I5Y766)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Sequence: MQQWRLLVVWFLLSPVPASAIKELPKAKNYEVVYPIRLHLLHKRETKEPEPKETFETELRYKMTVNGKVVELYLKKNNKLLAPGYLETYYNSSGNKVTTSPQIMDSCYYQGHIINEKDSAASISMCQGLRGYFSQADERYFIEPLSSEILDEQAHALFKDDPKEDQENSNCGVDDALWLQGLHQDVVLPATRLIKLNDGMVQEPKKYIEYYVVLDNGEFKKYNKNLDEIRKRVHEMANYVNMLYNKLDAHVALVGMEIWTDEDKIKITPDANTTLENFSKWRGNDLLKRKHHDVAQLISSTDFSGSTVGLAFMSSMCSPYHSVGIVQDHSNYHLRVAGTMAHEMGHNLGMIHDYLSCKCPSEVCVMEQSLRFHMPTDFSSCSRDNYRRFLEEKLSHCLFNSPLPSDIISTPVCGNQLLEMNEDCDCGTPKECTNKCCDAETCKIKAGFQCALGECCEKCQLKKPGVVCRAAKDECDLPEMCDGKSSHCPVDRFRVNGFPCQNGHGYCLKGNCPTLQQQCMDMWGPETKVANKSCYKQNEGGSKYGYCHVENGTHMPCKAKDAMCGKLFCEGGSGDLPWKGLTIAFLTCKLFDPEDINQGVDMVANGTKCGNNKVCINAECVDMEKTYKSANCSSKCKGHAVCDHELQCQCKEGWAPPDCEDSATVFRVSIMVGVLFPLAAIFVVIAIVIHHQSARRKQRRVQRLPPIKDAKLHKQKCRPQKVKDIQPQELITKPNFPPPPIPVSWML
InterPro domains: - IPR018358: Disintegrin, conserved site (conserved_site) [450-469]
- IPR001590: Peptidase M12B, ADAM/reprolysin (domain) [206-402]
- IPR001762: Disintegrin domain (domain) [410-496]
- IPR036436: Disintegrin domain superfamily (homologous_superfamily) [409-493]
- IPR024079: Metallopeptidase, catalytic domain superfamily (homologous_superfamily) [201-403]
- IPR006586: ADAM, cysteine-rich domain (domain) [495-623]
- IPR034027: Reprolysin domain, adamalysin-type (domain) [206-400]
- IPR000742: EGF-like domain (domain) [628-660]
- IPR002870: Peptidase M12B, propeptide (domain) [31-113]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008237 (metallopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0019953 (sexual reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0007276 (gamete generation), GO:0007283 (spermatogenesis), GO:0048232 (male gamete generation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure), GO:0009986 (cell surface)
Protein: Killer cell lectin-like receptor subfamily A member 16 (Q4Z8P4)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
Sequence: MSEQEVTFSTVRFQKTSGLQNRVRLEETLKPRKAGLRVCSVSWQFIVIALGILISLRLVIVAVLVTNIFQYGQQKHELQEFLNHHNNCSIMQSDIKLKNELLKKKSIECNLLESLNRDQNRLYNKTKTVLDFLQHTGRGDKVYWFCYGMKCYYFVMDRKPWSGCKQTCQSSGLSLLKIDDEDELKFLQLVVPSDVCWIGLSYDNKKKDWSWVDNGPSKLALNTRKYNIRDGGCMLLSKTRLDNGNCDQVFICICAKRLDKFPH
InterPro domains: - IPR013600: Ly49-like, N-terminal (domain) [40-154]
- IPR016186: C-type lectin-like/link domain superfamily (homologous_superfamily) [128-263]
- IPR052013: Mouse Killer cell lectin-like receptors (family) [1-263]
- IPR016187: C-type lectin fold (homologous_superfamily) [122-259]
- IPR001304: C-type lectin-like (domain) [140-255]
- IPR033992: Natural killer cell receptor-like, C-type lectin-like domain (domain) [143-256]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:0009615 (response to virus), GO:0043207 (response to external biotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Shewanella-like protein phosphatase 2 (AtSLP2) (EC 3.1.-.-) (Q944L7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Shows phosphatase activity, hydrolyzing the artificial substrate para-nitrophenylphosphate (pNPP) in vitro.
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:21976480}.
Sequence: MSSRENPSGICKSIPKLISSFVDTFVDYSVSGIFLPQDPSSQNEILQTRFEKPERLVAIGDLHGDLEKSREAFKIAGLIDSSDRWTGGSTMVVQVGDVLDRGGEELKILYFLEKLKREAERAGGKILTMNGNHEIMNIEGDFRYVTKKGLEEFQIWADWYCLGNKMKTLCSGLDKPKDPYEGIPMSFPRMRADCFEGIRARIAALRPDGPIAKRFLTKNQTVAVVGDSVFVHGGLLAEHIEYGLERINEEVRGWINGFKGGRYAPAYCRGGNSVVWLRKFSEEMAHKCDCAALEHALSTIPGVKRMIMGHTIQDAGINGVCNDKAIRIDVGMSKGCADGLPEVLEIRRDSGVRIVTSNPLYKENLYSHVAPDSKTGLGLLVPVPKQVEVKA
InterPro domains: - IPR004843: Calcineurin-like, phosphoesterase domain (domain) [55-164]
- IPR029052: Metallo-dependent phosphatase-like (homologous_superfamily) [33-360]
- IPR041787: Shewanella-like phosphatase, metallophosphatase domain (domain) [57-343]
Interaction partners: - AT5g11000/T30N20_270
- PP2A regulatory subunit TAP46
- Mitochondrial intermembrane space import and assembly protein 40 homolog
- Exocyst subunit Exo70 family protein
- Serine/threonine-protein phosphatase 4 regulatory subunit-like protein
- At4g26810
- At3g03590
- SWIB/MDM2 domain superfamily protein
- AGAMOUS-like 67
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0043167 (ion binding), GO:0016787 (hydrolase activity), GO:0043169 (cation binding), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0046872 (metal ion binding), GO:0046914 (transition metal ion binding), GO:0016791 (phosphatase activity), GO:0030145 (manganese ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:0006066 (alcohol metabolic process), GO:0005975 (carbohydrate metabolic process), GO:0044282 (small molecule catabolic process), GO:1901575 (organic substance catabolic process), GO:0044248 (cellular catabolic process), GO:0044262 (cellular carbohydrate metabolic process), GO:0044275 (cellular carbohydrate catabolic process), GO:0006020 (inositol metabolic process), GO:1901616 (organic hydroxy compound catabolic process), GO:0046164 (alcohol catabolic process), GO:0016052 (carbohydrate catabolic process), GO:0019751 (polyol metabolic process), GO:0046174 (polyol catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0005773 (vacuole), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000325 (plant-type vacuole), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Dehydrogenase/reductase (SDR family) member 3 L homeolog precursor (Dehydrogenase/reductase 3) (MGC80882 protein) (Q6GNT6)
Organism: Xenopus laevis (African clawed frog)
Function: Not known
Sequence: MDMSALGRLLLLPVQILFSILKVAANLLMPNKLRDLSGDTVLITGGGRGIGRHLAREFAKQKAKKIILWGRTERCLKETAEEIKQMGTDCSYFVCDVGNREEVYQQAKAVREKVGDVTILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCINSVLALSAIPGAIDYCTSKSSSFAFMESLTLGLLDCPGVNATTVLPYHTSTEMFQGMRVRFPSLFPSLKPETVATKTVEAVQKNKAFLLLPWTMHALVILKSILPQSALEEIHRFSGAYTCMNTFKGRT
InterPro domains: - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [30-293]
- IPR057326: Ketoreductase domain (domain) [39-222]
- IPR002347: Short-chain dehydrogenase/reductase SDR (family) [40-229]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor), GO:0004745 (NAD-retinol dehydrogenase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0009987 (cellular process), GO:0065008 (regulation of biological quality), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0042445 (hormone metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0006082 (organic acid metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0042573 (retinoic acid metabolic process), GO:0010817 (regulation of hormone levels), GO:0006720 (isoprenoid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0016053 (organic acid biosynthetic process), GO:0008299 (isoprenoid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process), GO:0006721 (terpenoid metabolic process), GO:0016114 (terpenoid biosynthetic process), GO:0016101 (diterpenoid metabolic process), GO:0016102 (diterpenoid biosynthetic process), GO:0072330 (monocarboxylic acid biosynthetic process), GO:0032787 (monocarboxylic acid metabolic process), GO:0001523 (retinoid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005811 (lipid droplet)
Protein: DnaJ homolog subfamily C member 17 (Q91WT4)
Organism: Mus musculus (Mouse)
Function: May negatively affect PAX8-induced thyroglobulin/TG transcription.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:D3ZSC8}. Nucleus {ECO:0000250|UniProtKB:D3ZSC8}. Note=Predominantly nuclear. {ECO:0000250|UniProtKB:D3ZSC8}.
Sequence: MAVTKELLQMDLYALLGIEEKAADKEVKKAYRQKALSCHPDKNPDNPRAAELFHQLSQALEVLTDAAARAAYDKVRKAKKQAAERTQRLDENRKKVKLDLEARERQAQAHGSEEEEESRSATTLEQEIARLREEGSRQLEEQQRLIQEQIRQDREQRLRGRTENTEGKGTPKLKLKWKCKKEDESQGGYSRDVLLRLLQKYGEVLNLVLSRKKAGNAIVEFATVRAAELAVRNEVGLADNPLKVSWLEGQPQSTVDPGPPGLSKGSVLSERDFESLVMMRMRQAAERQQLIAQMQQEDEGRPT
InterPro domains: - IPR035979: RNA-binding domain superfamily (homologous_superfamily) [190-259]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [162-258]
- IPR052094: Pre-mRNA-splicing and ERAD-associated protein (family) [1-298]
- IPR034254: DNAJC17, RNA recognition motif (domain) [184-247]
- IPR036869: Chaperone J-domain superfamily (homologous_superfamily) [3-102]
- IPR001623: DnaJ domain (domain) [10-76]
- IPR000504: RNA recognition motif domain (domain) [189-233]
Interaction partners: - TCF3 fusion partner homolog
- WD repeat-containing protein 53
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0008380 (RNA splicing), GO:0006397 (mRNA processing), GO:0016071 (mRNA metabolic process), GO:0000398 (mRNA splicing, via spliceosome), GO:0000375 (RNA splicing, via transesterification reactions), GO:0000377 (RNA splicing, via transesterification reactions with bulged adenosine as nucleophile)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: 2-hydroxyethylphosphonate dioxygenase (EC 1.13.11.72) (Hydroxyethylphosphonate dioxygenase) (Phosphinothricin tripeptide biosynthesis protein D) (Q5IW40)
Organism: Streptomyces viridochromogenes (strain DSM 40736 / JCM 4977 / BCRC 1201 / Tue 494)
Function: Non-heme-dependent dioxygenase that catalyzes the conversion of 2-hydroxyethylphosphonate (HEP) to hydroxymethylphosphonate (HMP) in the biosynthesis of phosphinothricin tripeptide (PTT). PTT contains the unusual amino acid phosphinothricin attached to 2 alanine residues. Synthetic phosphinothricin (glufosinate) is a key component of commercial herbicides.
Sequence: MRIDPFKLAHWMNARKYTAAQTADLAGLPLDDLRRLLGDEANEPDPAAATALAEALSVEPSQLAADAHRNLTVVHKSAEEMHASRRPIQRDGIHFYNYYTLAAPEGRVAPVVLDILCPSDRLPALNNGHLEPAITVNLGPGDINGRWGEEITPQTWRVLHANHGGDRWITGDSYVEPSYCPHSYSLAGDAPARIVSYTAQSNISPLMTEANNWSTGAFEEALKALSGKVSAGSVLDLFLARRAHTRTSAAEAAGVPPADLEAALRSPASETGLTVLRTLGRALGFDYRVLLPADDQHDGVGKTWTTIEDSRRSRRTFGTYEAASMASAAHLPDLVGSFLRVDADGRGADLIDHAENHYVVTEGRLTLEWDGPDGPASVELEPDGSAWTGPFVRHRWHGTGTVLKFGSGAHLGYQDWLELTNTFEPAATLRRGRRDLAGWGYDN
InterPro domains: - IPR011051: RmlC-like cupin domain superfamily (homologous_superfamily) [332-401]
- IPR001387: Cro/C1-type, helix-turn-helix domain (domain) [7-290]
- IPR010982: Lambda repressor-like, DNA-binding domain superfamily (homologous_superfamily) [206-291]
- IPR014710: RmlC-like jelly roll fold (homologous_superfamily) [82-408]
Interaction partners: - Phosphonoacetaldehyde reductase
- PhpE
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0043167 (ion binding), GO:0016491 (oxidoreductase activity), GO:0043169 (cation binding), GO:0051213 (dioxygenase activity), GO:0016701 (oxidoreductase activity, acting on single donors with incorporation of molecular oxygen), GO:0016702 (oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen), GO:0046872 (metal ion binding), GO:0046914 (transition metal ion binding), GO:0005506 (iron ion binding), GO:0008198 (ferrous iron binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044249 (cellular biosynthetic process), GO:0019637 (organophosphate metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006793 (phosphorus metabolic process), GO:0090407 (organophosphate biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Actin-like protein arp6 (O94241)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Sequence: MGLPPKTIVLDNGAYHIKAGFAGGKVVEIPNCLTRSKDGNRLFLGNELANCNDFTTLQFRRAHEKGYLVHWSTETAVWDLVMRNVGVMEPSMADYSLLLTQPVFTMPSIEHNTIQLVFEEFQFDAYLPCTPAELIPWDHGSFTMNQEDAYTGQHGECVLVIDSGYSFTHIIPVIDFSVQEQAVKRVDVGGKLLTNYLKEVISYRKYNMMEETYIVNEIKESVCYVSQNFKEDMEICHEKPRSKLEICYALPDYSTGKHGYIVRDINQKIEQQVLNLSNERFMIPELLFSPSDIEIREAGIPEAVMQSVTHFPENIQAMLLENVVTIGGNCKFPGFHKRLSSELRSLAPANWEVKVFEPSDPICFPWKKASHMPLEHWNANKITRSEYSEHGANIMTRKRRI
InterPro domains: - IPR043129: ATPase, nucleotide binding domain (homologous_superfamily) [5-399]
- IPR004000: Actin family (family) [5-400]
Interaction partners: - RuvB-like helicase 1
- SWR1 complex subunit vps71
- Helicase swr1
- RuvB-like helicase 2
- Histone H2A.Z
- SWR complex protein 2
- SWR1-complex protein 4
- Protein AF-9 homolog
- SWR1-complex protein 5
- Multicopy suppressor of chk1 protein 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0003682 (chromatin binding), GO:0005515 (protein binding), GO:0031491 (nucleosome binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006325 (chromatin organization), GO:0006338 (chromatin remodeling)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0032153 (cell division site), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0005816 (spindle pole body), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0044732 (mitotic spindle pole body), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0005634 (nucleus), GO:0015630 (microtubule cytoskeleton)
Protein: Tumor necrosis factor receptor superfamily member 4 (MRC OX40) (OX40 antigen) (OX40L receptor) (CD antigen CD134) (P15725)
Organism: Rattus norvegicus (Rat)
Function: Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity (By similarity).
Subcellular location: Membrane; Single-pass type I membrane protein.
Sequence: MYVWVQQPTAFLLLGLSLGVTVKLNCVKDTYPSGHKCCRECQPGHGMVSRCDHTRDTVCHPCEPGFYNEAVNYDTCKQCTQCNHRSGSELKQNCTPTEDTVCQCRPGTQPRQDSSHKLGVDCVPCPPGHFSPGSNQACKPWTNCTLSGKQIRHPASNSLDTVCEDRSLLATLLWETQRTTFRPTTVPSTTVWPRTSQLPSTPTLVAPEGPAFAVILGLGLGLLAPLTVLLALYLLRKAWRSPNTPKPCWGNSFRTPIQEEQTDTHFTLAKI
InterPro domains: - IPR020445: Tumour necrosis factor receptor 4 (family) [9-271]
- IPR001368: TNFR/NGFR cysteine-rich region (domain) [25-163]
- IPR034022: Tumour necrosis factor receptor 4, N-terminal (domain) [24-167]
Interaction partners: - Tumor necrosis factor ligand superfamily member 4
- CD70 antigen
- T-lymphocyte activation antigen CD80
- T-lymphocyte activation antigen CD86
- ICOS ligand
- TNF receptor superfamily member 9
- CD40 ligand
- Inducible T-cell costimulator
- CD27 antigen
- TNF superfamily member 9
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003823 (antigen binding), GO:0005515 (protein binding), GO:0019904 (protein domain specific binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0042742 (defense response to bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098552 (side of membrane), GO:0009986 (cell surface), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0009897 (external side of plasma membrane), GO:0005886 (plasma membrane)
Protein: V-ral simian leukemia viral oncogene homolog Bb (Ras related) (EC 3.6.5.2) (Zgc:86798) (Q6IQE6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
Sequence: MAVNKSKAQSSLVLHKVIMVGSGGVGKSALTLQFMYDEFVEDYEPTKADSYRKKVVLDGEEVQIDILDTAGQEDYAAIRDNYFRSGEGFLLVFSITEPESFSASAEFREQILRVKAEEDKIPLLVVGNKSDLEERRQVSADEARSKADEWGVQYVETSAKTRANVDKVFFDLMREVRTKKMSENKEKNLKKGGKKKKSLKERCTLL
InterPro domains: - IPR001806: Small GTPase (family) [8-206]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [8-191]
- IPR005225: Small GTP-binding domain (domain) [16-169]
- IPR020849: Small GTPase, Ras-type (family) [15-192]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048870 (cell motility), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0016477 (cell migration), GO:0048863 (stem cell differentiation), GO:0048864 (stem cell development), GO:0060485 (mesenchyme development), GO:0048762 (mesenchymal cell differentiation), GO:0001667 (ameboidal-type cell migration), GO:0014033 (neural crest cell differentiation), GO:0014032 (neural crest cell development), GO:0090497 (mesenchymal cell migration), GO:0001755 (neural crest cell migration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)