Protein: Leukocyte elastase inhibitor-like protein (A0A139WIH2)
Organism: Tribolium castaneum (Red flour beetle)
Sequence: MRVILGLVFGILLSASTMAEIASELQVLQGNNQFTSKMYKLLSQKKGNIIFSPISMHAVLSMAYQGAQGSTAEHFASTLQVPEAKIAAEGYSEVMKRLNSVQNVTLLMANKVFLKNGFTLLTDFETAVTKSFQSEVQLVDFAQNEAAAKTINDWVEVQTREKIKDLIKKDDLNELTRLVLVNAIYFKGNWKHKFRKEETRTEPFYLNDVDKVEVQMMHTKNKFNYKNDEALDAQILEMPYTNENLSMVIILPNQRNGIGELEKKLENYNLSEITTNMWNTEVNVALPKFKIEQTIDLEEALKKLGLGEIFDQDKANFRGMIELKPNENLYVSKVIQKAFIEVNEEGAEAAAATGVHVMMKRSLVFPEEFNADHPFIYALKISKAKSGNVLFYGKVAQLLPFSPTICRQIFKAKRLIFFTVFCKYDYEGLHLFLCNSSRIVFHCGPSIRIFVDSDIGKRKKSFICWKNHKTFVKSKYKTYIKYSKAIHLNDKNLYNMLELVQQHVFLI
InterPro domains: - IPR036186: Serpin superfamily (homologous_superfamily) [18-396]
- IPR042178: Serpin superfamily, domain 1 (homologous_superfamily) [43-339]
- IPR042185: Serpin superfamily, domain 2 (homologous_superfamily) [186-391]
- IPR023796: Serpin domain (domain) [30-398]
- IPR023795: Serpin, conserved site (conserved_site) [369-379]
- IPR000215: Serpin family (family) [29-397]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140678 (molecular function inhibitor activity), GO:0061134 (peptidase regulator activity), GO:0004857 (enzyme inhibitor activity), GO:0061135 (endopeptidase regulator activity), GO:0030414 (peptidase inhibitor activity), GO:0004866 (endopeptidase inhibitor activity), GO:0004867 (serine-type endopeptidase inhibitor activity), GO:0004869 (cysteine-type endopeptidase inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0065008 (regulation of biological quality), GO:0019222 (regulation of metabolic process), GO:0065009 (regulation of molecular function), GO:0009892 (negative regulation of metabolic process), GO:0050790 (regulation of catalytic activity), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0032351 (negative regulation of hormone metabolic process), GO:0032350 (regulation of hormone metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0044092 (negative regulation of molecular function), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0010817 (regulation of hormone levels), GO:0043086 (negative regulation of catalytic activity), GO:0034248 (regulation of amide metabolic process), GO:0051246 (regulation of protein metabolic process), GO:0051336 (regulation of hydrolase activity), GO:0051248 (negative regulation of protein metabolic process), GO:0034249 (negative regulation of amide metabolic process), GO:0010629 (negative regulation of gene expression), GO:0010468 (regulation of gene expression), GO:0051346 (negative regulation of hydrolase activity), GO:0030162 (regulation of proteolysis), GO:0052547 (regulation of peptidase activity), GO:0045861 (negative regulation of proteolysis), GO:1903317 (regulation of protein maturation), GO:1903318 (negative regulation of protein maturation), GO:0070613 (regulation of protein processing), GO:0052548 (regulation of endopeptidase activity), GO:0010466 (negative regulation of peptidase activity), GO:0010955 (negative regulation of protein processing), GO:0010951 (negative regulation of endopeptidase activity)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)