Protein: protein kinase C (EC 2.7.11.13) (Q5ANK2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Sequence: MSTSQPSQQQNPEQVVNDIRQKIEKERKIIQGFNDVKRNTNNPEVIQKCKSKIIESQSMIDYYQETMNKLTRQMSRLNTNSSSRTASRSSVISEYKPSYSNFDLIKYECPSLGNKIQFMLQYLEFKLQVENKYSEANKKLSHLYLMDGDKSSSNAAEGGRAESDQRIQLLEKALKKYQKFSINDHEFDRDYEIMDSTKHSRKLLTGRLTVSITCIRDVDHIATALAKKRETVVVIKVDDLEKARTKPSKNDNWNEEMVIDVDKSHEIELAVMDKQNGIYVPVAVNWFSLFDLAEEIRKKKVAKDQGSSGWLPAANLPQTGGSGAGTGSSMTGGASYGATSPLPAHNDLRPSVSPSSDAKENKVSVSTWLSLEPGGQMLINLNFEKSITNGKQFRGPLGRHGAIRQKKEEVFEKHGHQFVQKQFYNIMSCALCGEFLRYTGYQCQDCKFLCHKKCYQKVVTKCISKSGSDYDAAQLNHRIPHRFEPITNHGTKWCCHCGYILPWGKKNVRKCTECGVMCHAQCTHLVPDFCGMSLQMANEILATIESTKVSPKKAQHQQSHAKPLPPKPPIESKPSMDSEETLHNEPSYKSLRPASVVHQDTNFVSKLPTTVQNKYQEPVELPPQQQNQVVPSTRRRGHGSTDLSFETGYGQQQHQHHRDVPQIVVEDHQHYNSNDNRDVEMEESKDEFDNFDYNNKYTENEILTDVQQDQVRSPFADQIQGVPETSHAKQQNQQVQQVQQQEELGHQRTHSSGKFGKSKRRKRKVGLDDFQFLAVLGKGNFGKVMLAESRHTSKLCAIKVLKKDFIVENDEAESVKSEKRVFLTANKEMHPFLLNLHCCFQTENRIYFVMEYISGGDLMWHIQKNRFTAKRAKFYACEVLLGLKYFHDNGIVYRDLKLDNILLTTKGHIKIGDYGLCKEDMWHKSTTSTFCGTPEFMAPEIVAGKAYDRSVDWWAFGVLLFQMLLCQSPFKGDDEDDIFNAIENDEVKYPINLSRQTVLVLQALLTKDPSQRLGSGPKDAEEIMEHPYFHDVNFDDVLNCRIPAPYIPEVQSEHDYSNFDKEFTSETPRLTPVETVLTSEMQEQFRGFSHISDNATI
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [767-1087]
- IPR035892: C2 domain superfamily (homologous_superfamily) [202-384]
- IPR046349: C1-like domain superfamily (homologous_superfamily) [406-534]
- IPR000961: AGC-kinase, C-terminal (domain) [1030-1097]
- IPR000008: C2 domain (domain) [189-311]
- IPR037778: Protein kinase C-like, C2 domain (domain) [208-315]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [891-903]
- IPR011072: HR1 rho-binding domain (domain) [2-184]
- IPR002219: Protein kinase C-like, phorbol ester/diacylglycerol-binding domain (domain) [414-532]
- IPR017892: Protein kinase, C-terminal (domain) [1050-1089]
- IPR017441: Protein kinase, ATP binding site (binding_site) [776-799]
- IPR000719: Protein kinase domain (domain) [770-1029]
- IPR037312: Protein kinase C-like, HR1 domain (domain) [110-181]
- IPR036274: HR1 repeat superfamily (homologous_superfamily) [113-183]
Interaction partners: - GTP-binding protein RHO1
- Mitogen-activated protein kinase kinase kinase
- Serine/threonine-protein kinase PKH2
- non-specific serine/threonine protein kinase
- M-phase inducer phosphatase
- Gag1-like clamp domain-containing protein
- Rho family guanine nucleotide exchange factor
- Rho family GTPase
- Cell division control protein 42 homolog
- Rho family guanine nucleotide exchange factor
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity), GO:0004697 (protein kinase C activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0031139 (positive regulation of conjugation with cellular fusion), GO:0071554 (cell wall organization or biogenesis), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0030447 (filamentous growth), GO:0071840 (cellular component organization or biogenesis), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0044238 (primary metabolic process), GO:0032005 (signal transduction involved in positive regulation of conjugation with cellular fusion), GO:0044182 (filamentous growth of a population of unicellular organisms), GO:0071852 (fungal-type cell wall organization or biogenesis), GO:0030968 (endoplasmic reticulum unfolded protein response), GO:0035556 (intracellular signal transduction), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0035966 (response to topologically incorrect protein), GO:0060255 (regulation of macromolecule metabolic process), GO:1901700 (response to oxygen-containing compound), GO:0016043 (cellular component organization), GO:0071555 (cell wall organization), GO:0010033 (response to organic substance), GO:0006793 (phosphorus metabolic process), GO:0031505 (fungal-type cell wall organization), GO:0071310 (cellular response to organic substance), GO:0062197 (cellular response to chemical stress), GO:0071470 (cellular response to osmotic stress), GO:0006796 (phosphate-containing compound metabolic process), GO:0045229 (external encapsulating structure organization), GO:1901701 (cellular response to oxygen-containing compound), GO:0048017 (inositol lipid-mediated signaling), GO:0048015 (phosphatidylinositol-mediated signaling), GO:0016310 (phosphorylation), GO:0006468 (protein phosphorylation), GO:0034620 (cellular response to unfolded protein)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0070938 (contractile ring), GO:0032153 (cell division site), GO:0030427 (site of polarized growth), GO:0005933 (cellular bud), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0005826 (actomyosin contractile ring), GO:0043229 (intracellular organelle), GO:0005935 (cellular bud neck), GO:0005938 (cell cortex), GO:0043228 (non-membrane-bounded organelle), GO:0030863 (cortical cytoskeleton), GO:0110085 (mitotic actomyosin contractile ring), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0030864 (cortical actin cytoskeleton), GO:0015629 (actin cytoskeleton)