wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4) (Q16204)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000305}. Note=May be a cytoskeletal protein.
Sequence: MADSASESDTDGAGGNSSSSAAMQSSCSSTSGGGGGGGGGGGGGKSGGIVISPFRLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGTSHGITRPSPRRSNSPDKFKRPTPPPSPNTQTPVQPPPPPPPPPMQPTVPSAATSQPTPSQHSAHPSSQP
InterPro domains: - IPR019152: Protein of unknown function DUF2046 (family) [1-430]
Interaction partners: - Nuclear receptor coactivator 4
- Proto-oncogene tyrosine-protein kinase receptor Ret
- Serine/threonine-protein phosphatase 4 catalytic subunit
- 3-mercaptopyruvate sulfurtransferase
- Tropomyosin alpha-3 chain
- Serine/threonine-protein phosphatase 4 regulatory subunit 1
- Protein patched homolog 1
- E3 ubiquitin-protein ligase TRIM33
- Sodium-dependent phosphate transport protein 2B
- Proto-oncogene tyrosine-protein kinase ROS
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhesion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Protein tesmin/TSO1-like CXC 8 (AtTCX8) (Q700D0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a role in development of both male and female reproductive tissues.
Subcellular location: Nucleus {ECO:0000305}.
Sequence: MTGNADSGKIATEKDPRKLVFTKLEVSPVFRESPVKELPLFPPISREHSEAKDKTDEEGITSRKHKGCRCKQSKCLKLYCDCFASGVVCTDCDCVDCHNNSEKCDAREAAMVNVLGRNPNAFSEKALGSLTDNQCKAAPDTKPGLLSRGCKCKRTRCLKKYCECFQANLLCSDNCKCINCKNVSEAFQPPAFSAHNSPQVYRRRRDRELTEWNSCPAPLFSIPDNSIQNALGSPMSCSPKLPYRKKRSLMGYTSTLLPDLGDLCSLLVAASESATTTAEDQNRIFTKPDDKEAIELSSESESRNVEEEIQSRGRLIELIDVQYNGEEDSQCKTKTSVNETDIYMEQERAVLETFRDCLQKFIKSRLES
InterPro domains: - IPR028307: Lin-54 family (family) [52-359]
- IPR033467: Tesmin/TSO1-like CXC domain (domain) [63-186]
- IPR005172: CRC domain (domain) [64-185]
Interaction partners: - Proline-rich spliceosome-associated
- Retinoblastoma-related protein 1
- THO complex subunit 4B
- F-box associated ubiquitination effector family protein
- Ras-related protein RABG3d
- Protein ALWAYS EARLY 3
- Transcription factor E2FC
- Protein ALWAYS EARLY 2
- Protein ALWAYS EARLY 1
- Histone-binding protein MSI1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: E3 SUMO-protein ligase NSE2 (E3 SUMO-protein transferase NSE2) (Non-structural maintenance of chromosomes element 2 homolog) (Q8I8I0)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MSDFVSDFSDGGKIKKLLEQSVEQSVEHAVNVVHMKIKHQSLNKAMNQVKNSSATMEEFEEVWKERSKAVEQKRINVKNLHEFKNFVKAVESAAGQAGAEVNDQANGTAYDEDLIMEDSGSEVFSFYDPWSKALIKNPIRNKMCGHIYDRDSVMPIIMDRIGIRCPVLGCANLCYIQPDHLVQDANVQQKIQQSMSNAIVDVTASEEDEE
InterPro domains: - IPR026846: E3 SUMO-protein ligase Nse2 (Mms21) (family) [18-196]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [121-205]
- IPR004181: Zinc finger, MIZ-type (domain) [111-196]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0019787 (ubiquitin-like protein transferase activity), GO:0019789 (SUMO transferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0033554 (cellular response to stress), GO:0006259 (DNA metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0006974 (cellular response to DNA damage stimulus), GO:0006310 (DNA recombination), GO:0006281 (DNA repair), GO:0000725 (recombinational repair), GO:0006302 (double-strand break repair), GO:0000724 (double-strand break repair via homologous recombination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: At2g26500 (Cytochrome b6f complex subunit (PetM)) (Expressed protein) (O48717)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Sequence: MATAAAPAVISWTRSGIVSKSGQTQKKSEMKVSYITGLNSYGGLKAQNNKVVSMGSPLCTEQCFANVVMSLKGRRGNGGALSTTCNAVGEIFKIAAIMNALTLVGVAVGFVLLRIETSVEEAEAE
InterPro domains: - IPR053333: Cytochrome b6-f complex subunit 7 (family) [1-123]
- IPR012595: PetM of cytochrome b6/f complex subunit 7 (family) [87-119]
Interaction partners: - Cytochrome b6-f complex iron-sulfur subunit, chloroplastic
- Cytochrome f
- Cytochrome b6-f complex subunit 6
- Cytochrome b6-f complex subunit 5
- Cytochrome b6-f complex subunit 8
- Cytochrome b
- Plastocyanin major isoform, chloroplastic
- Cytochrome b6-f complex subunit 4
- Small ribosomal subunit protein uS14z/uS14y/uS14x
- Cytochrome b6
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0071840 (cellular component organization or biogenesis), GO:0044237 (cellular metabolic process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0016043 (cellular component organization), GO:0031323 (regulation of cellular metabolic process), GO:0044085 (cellular component biogenesis), GO:0006091 (generation of precursor metabolites and energy), GO:0015979 (photosynthesis), GO:0010109 (regulation of photosynthesis), GO:0043933 (protein-containing complex organization), GO:0019684 (photosynthesis, light reaction), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly), GO:0010207 (photosystem II assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0031975 (envelope), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0034357 (photosynthetic membrane), GO:0043229 (intracellular organelle), GO:0019867 (outer membrane), GO:0009536 (plastid), GO:0043228 (non-membrane-bounded organelle), GO:0043227 (membrane-bounded organelle), GO:0009507 (chloroplast), GO:0042651 (thylakoid membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031976 (plastid thylakoid), GO:0098588 (bounding membrane of organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0009526 (plastid envelope), GO:0042170 (plastid membrane), GO:0031968 (organelle outer membrane), GO:0009941 (chloroplast envelope), GO:0009579 (thylakoid), GO:0055035 (plastid thylakoid membrane), GO:0009535 (chloroplast thylakoid membrane), GO:0009534 (chloroplast thylakoid)
Protein: MOB kinase activator-like 1A (Mob1 homolog 1A) (Mps one binder kinase activator-like 1A) (Q9FHI1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Plays a key role in regulation of cell expansion and cell division. Required for proper plant development, the correct patterning of the root meristem and the control of root growth. Involved in both sporogenesis and gametogenesis.
Subcellular location: Nucleus {ECO:0000269|PubMed:15469496, ECO:0000269|PubMed:21641974, ECO:0000269|PubMed:26685188}. Cell membrane {ECO:0000269|PubMed:26685188}. Vacuole membrane {ECO:0000269|PubMed:26685188}. Note=Observed at the plasma membrane and in the nucleus when associated with SIK1. {ECO:0000269|PubMed:26685188}.
Sequence: MSLFGLGRNQKTFRPKKSAPSGSKGAQLRKHIDATLGSGNLREAVRLPPGEDANEWLAVNTVDFFNQVNLLYGTLTEFCTPDNCPTMTAGPKYEYRWADGVQIKKPIEVSAPKYVEYLMDWIETQLDDETLFPQRLGAPFPQNFKDVVKTIFKRLFRVYAHIYHSHFQKIVSLKEEAHLNTCFKHFILFTHEFGLIDKKELAPLQELIESIISPY
InterPro domains: - IPR005301: MOB kinase activator family (family) [9-212]
- IPR036703: MOB kinase activator superfamily (homologous_superfamily) [2-213]
Interaction partners: - Zinc finger CCCH domain-containing protein 24
- Oxysterol-binding protein-related protein 1D
- tRNA wybutosine-synthesizing protein 2/3/4
- AT3g17020/K14A17_14
- Protein NLP2
- Sugar transport protein 2
- Rop guanine nucleotide exchange factor 14
- Protein NLP1
- Protein NLP3
- 65-kDa microtubule-associated protein 6
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0009987 (cellular process), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0008283 (cell population proliferation), GO:0050794 (regulation of cellular process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0062012 (regulation of small molecule metabolic process), GO:0046890 (regulation of lipid biosynthetic process), GO:0010565 (regulation of cellular ketone metabolic process), GO:0019216 (regulation of lipid metabolic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0042304 (regulation of fatty acid biosynthetic process), GO:0019217 (regulation of fatty acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 (Q9UBI6)
Organism: Homo sapiens (Human)
Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Sequence: MSSKTASTNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDKKTCIIL
InterPro domains: - IPR015898: G-protein, gamma subunit-like domain (domain) [7-72]
- IPR036284: G-protein gamma-like domain superfamily (homologous_superfamily) [2-72]
- IPR001770: G-protein, gamma subunit (family) [2-72]
Interaction partners: - Guanine nucleotide-binding protein subunit beta-4
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein subunit alpha-12
- B2 bradykinin receptor
- Muscarinic acetylcholine receptor M2
- 5-hydroxytryptamine receptor 7
- C-X-C chemokine receptor type 4
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0050794 (regulation of cellular process), GO:0010646 (regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0008277 (regulation of G protein-coupled receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005829 (cytosol), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)
Protein: DUF1476 domain-containing protein (A1B602)
Organism: Paracoccus denitrificans (strain Pd 1222)
Function: Not known
Sequence: MTTFDDRERAHEAKFAHDAELNFKAEARRNRLLGEWAAGLLGKTGDDARAYALTVVTSDFDEPGDEDVFRKLAADLEGKADEETIRAKMVELRATAREQIISEI
InterPro domains: - IPR038293: ATPase inhibitor subunit zeta superfamily (homologous_superfamily) [1-104]
- IPR009945: ATPase inhibitor subunit zeta (family) [1-103]
Interaction partners: - ATP synthase gamma chain
- ATP synthase subunit alpha
- ATP synthase subunit beta
- ATP synthase subunit c
- ATP synthase subunit delta
- ATP synthase epsilon chain
- ATP synthase subunit a
- Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Phosphoribosylformylglycinamidine synthase subunit PurS
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:0070887 (cellular response to chemical stimulus), GO:0010035 (response to inorganic substance), GO:0010038 (response to metal ion), GO:0071241 (cellular response to inorganic substance), GO:0071248 (cellular response to metal ion), GO:0010039 (response to iron ion), GO:0071281 (cellular response to iron ion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0140737 (encapsulin nanocompartment)
Protein: cAMP-dependent protein kinase inhibitor gamma (F7F4X2)
Organism: Rattus norvegicus (Rat)
Function: Not known
Sequence: MFGECDGPGMQLQPSGSLSKGNGSLLCTERWKLSKWVEWLTSSGRELDYNKWGLTWPETGKHPLKPRSAFHLGETGREKGQERAVCPTCPALLSSGFLFYLPILLTWDLCAWRPGSCLRSDATGMMEVESSYSDFISCDRTGRRNAVPDIQGDSEAVSVRKLAGDMGELALEGAEGQAEGSTPDKEASSQPESSDANTSS
InterPro domains: - IPR004171: cAMP-dependent protein kinase inhibitor (family) [62-200]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0008603 (cAMP-dependent protein kinase regulator activity), GO:0030291 (protein serine/threonine kinase inhibitor activity), GO:0004862 (cAMP-dependent protein kinase inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Superoxide dismutase [Cu-Zn] (EC 1.15.1.1) (Q9BLY4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MSSIKIEFAVQMRRGDESYAGALRSALDGVGQVEIDTQEGRVIIQTQRPWSEIQDKIEATGVRAVLSGFGGQSAVALINTTGSVVDKTPIQGVVRFTTITADKKPGVVVDGVVDGLSPGLHGLHIHESGDTSAGCSSVGEHYNPRQSPHGSPAAGAEERHAGDLGNIRADENGRATFRFVDPVLEVWDIIGRAVVLTANADDLGRGGNDQSLIDGNSGERIACGIIARSAGILENFKRICACDGVTLWDERNKPLAGKDRSQKL
InterPro domains: - IPR001424: Superoxide dismutase, copper/zinc binding domain (domain) [72-227]
- IPR036423: Superoxide dismutase-like, copper/zinc binding domain superfamily (homologous_superfamily) [74-254]
- IPR024134: Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone (family) [45-253]
- IPR018152: Superoxide dismutase, copper/zinc, binding site (binding_site) [215-226]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140104 (molecular carrier activity), GO:0016530 (metallochaperone activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0065007 (biological regulation), GO:0032501 (multicellular organismal process), GO:0065008 (regulation of biological quality), GO:0008340 (determination of adult lifespan), GO:0006950 (response to stress), GO:0006979 (response to oxidative stress), GO:0031647 (regulation of protein stability), GO:0050821 (protein stabilization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0042579 (microbody), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005777 (peroxisome)
Protein: Pyridoxal phosphate homeostasis protein (PLP homeostasis protein) (P67080)
Organism: Escherichia coli (strain K12)
Function: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. May have a carrier function to deliver PLP to the target enzymes or a protective function so that PLP does not inactivate essential lysines in proteins. Does not have amino acid racemase activity.
Sequence: MNDIAHNLAQVRDKISAAATRCGRSPEEITLLAVSKTKPASAIAEAIDAGQRQFGENYVQEGVDKIRHFQELGVTGLEWHFIGPLQSNKSRLVAEHFDWCHTIDRLRIATRLNDQRPAELPPLNVLIQINISDENSKSGIQLAELDELAAAVAELPRLRLRGLMAIPAPESEYVRQFEVARQMAVAFAGLKTRYPHIDTLSLGMSDDMEAAIAAGSTMVRIGTAIFGARDYSKK
InterPro domains: - IPR029066: PLP-binding barrel (homologous_superfamily) [1-228]
- IPR001608: Alanine racemase, N-terminal (domain) [7-229]
- IPR011078: Pyridoxal phosphate homeostasis protein (family) [1-234]
Interaction partners: - Uncharacterized protein YggT
- UPF0235 protein YggU
- dITP/XTP pyrophosphatase
- Heme chaperone HemW
- Pyrroline-5-carboxylate reductase
- dTTP/UTP pyrophosphatase
- Purine nucleoside phosphorylase YfiH
- Pyridoxal kinase PdxY
- Pyridoxine/pyridoxal/pyridoxamine kinase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016830 (carbon-carbon lyase activity), GO:0016832 (aldehyde-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0044282 (small molecule catabolic process), GO:0006082 (organic acid metabolic process), GO:0044248 (cellular catabolic process), GO:0005996 (monosaccharide metabolic process), GO:0005975 (carbohydrate metabolic process), GO:1901575 (organic substance catabolic process), GO:0016054 (organic acid catabolic process), GO:0046365 (monosaccharide catabolic process), GO:0043436 (oxoacid metabolic process), GO:0016052 (carbohydrate catabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0046395 (carboxylic acid catabolic process), GO:0032787 (monocarboxylic acid metabolic process), GO:0072329 (monocarboxylic acid catabolic process), GO:0006063 (uronic acid metabolic process), GO:0019585 (glucuronate metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)