Protein: Protein FLOWERING LOCUS T (Q9SXZ2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the mobile flower-promoting signal (floral stimulus or florigen). Promotes the transition from vegetative growth to flowering. Required for 'SEPALLATA3' (SEP3) and 'FRUITFULL' (FUL) accumulation in mature rosette leaves. Seems to acts in parallel with 'LEAFY' to induce flowering by regulating 'APETALA1'. Translated in leaves and then transported to the shoot apical meristem where it activates the transcription of several floral meristem identity genes. May play a role in both the autonomous and the long-day flowering pathways.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16099979}. Nucleus {ECO:0000269|PubMed:16099979, ECO:0000269|PubMed:22529749}. Endoplasmic reticulum {ECO:0000269|PubMed:22529749}.
Sequence: MSINIRDPLIVSRVVGDVLDPFNRSITLKVTYGQREVTNGLDLRPSQVQNKPRVEIGGEDLRNFYTLVMVDPDVPSPSNPHLREYLHWLVTDIPATTGTTFGNEIVCYENPSPTAGIHRVVFILFRQLGRQTVYAPGWRQNFNTREFAEIYNLGLPVAAVFYNCQRESGCGGRRL
InterPro domains: - IPR035810: Phosphatidylethanolamine-binding protein, eukaryotic (family) [9-169]
- IPR008914: Phosphatidylethanolamine-binding protein (family) [52-132]
- IPR036610: PEBP-like superfamily (homologous_superfamily) [1-168]
- IPR001858: Phosphatidylethanolamine-binding, conserved site (conserved_site) [65-87]
Interaction partners: - UPF0235 protein At5g63440
- Protein FD
- Protein TWIN SISTER of FT
- Zinc finger protein CONSTANS
- Small ribosomal subunit protein mS29
- Floral homeotic protein APETALA 1
- Large ribosomal subunit protein mL46
- At1g64880
- Large ribosomal subunit protein mL43
- Large ribosomal subunit protein uL23m
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0050793 (regulation of developmental process), GO:0010022 (meristem determinacy), GO:2000243 (positive regulation of reproductive process), GO:0048856 (anatomical structure development), GO:0051239 (regulation of multicellular organismal process), GO:0010073 (meristem maintenance), GO:2000241 (regulation of reproductive process), GO:0051094 (positive regulation of developmental process), GO:0051240 (positive regulation of multicellular organismal process), GO:0048582 (positive regulation of post-embryonic development), GO:0048580 (regulation of post-embryonic development), GO:0009911 (positive regulation of flower development), GO:0048831 (regulation of shoot system development), GO:2000026 (regulation of multicellular organismal development), GO:0009888 (tissue development), GO:0009909 (regulation of flower development), GO:0048507 (meristem development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)