Protein: Phospholipid-transporting ATPase (Q5ADR3)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein
Sequence: MSNYNRTDNSKSNANPNPNANPNNPFSDNANNLIDLDLESNPYGDFNPNHVYPQTQRNTTTNTTTTTTTPHDPFADQFVLTDDSDEDNDDDDDVDGHNAHNTSFASSSQNRQVPLLNTANIPKSPTNRFFNTHNTNNNEYINMTDKQETSRDFDITHIFRKLKSKITGKPANLGLNDRQQSHQQQQPREINIMNHSANAGFGYYGNHISTTKYNIATFLPKFLFEQFSKYANLFFLVTSIIQQVPHVSPTNRYTTIGTLIVVLVVAAIKEMFEDIKRANADKELNRTKVLVLDPVTGNFTLKKWIKVQVGDVVQVLNEEPFPADLILLSSSEPEGLCYIETANLDGETNLKIKQAIPETAHLVNPRDLVKDLNNAQILSEQPNSSLYTYEGNLKNFRRGPDIPLSPEQMLLRGATLRNTQWINGVVIFTGHETKLMRNATAAPIKRTDVERIINLQILALFGVLIVLALISSIGNVIKVKVDGDKLGYLQLEGISMAKLFFQDLLTYWILFSNLVPISLFVTVELIKYYQAFMIGSDLDMYYEETDTPTGVRTSSLVEELGQIDYIFSDKTGTLTRNVMEFKSCSIGGRCYIEEIPEDGHAQVIDGIEIGYHTFDQLHADLKNTSTQQSAIINEFLTLLSTCHTVIPEVTEEKINYQAASPDEGALVQGAADLGYKFTIRRPKGVTIENTLTGNSSEYELLNICEFNSTRKRMSAIFRCPDGVIRLFCKGADTVILERLSQDEPQPFVDSTLRHLEDFAAEGLRTLCIASRIISDEEYNSWSQTYYEASTSLDNRSDKLDAAAELIEKDLFLLGATAIEDKLQDGVPETIHTLQQAGIKIWVLTGDRQETAINIGMSCKLLSEDMNLLIINEQTKNDTRLNLQEKLTAIQEHQFDAEDGSLESSLALIIDGHSLGYALEPDLEDLLIELGSRCRAVICCRVSPLQKALVVKMVKRKKKTSLLLAIGDGANDVSMIQAAHVGVGISGMEGMQAARSADVSIGQFKFLKKLLLVHGAWSYQRLSNAILYSFYKNIALYMTQFWFVFTNGFSGQSIAESWTLTFYNVLFTSLPPFVLGVFDQFVSARLLDRYPQLYQLGQKRKFFNVAIFWTWILNGFYHSAVIFLCSFFIYRYMNVASNGQTTDNWSWGVAVYTTCTLTALGKAALVVTMWTKFTVIAIPGSFLLWLGWYPAYATIAPMINVSDEYRGVLRMTYPLITFWGMVFGVAILCLLRDFAWKYFKRRYNPESYHYVQEIQKYNIQDYRPRMEQFQKAIRKVRQVQRIKKQRGFAFSQVEGQDQDKIVRLYDTTKKRGVFGELSESK
InterPro domains: - IPR023214: HAD superfamily (homologous_superfamily) [810-1005]
- IPR036412: HAD-like superfamily (homologous_superfamily) [555-1010]
- IPR032631: P-type ATPase, N-terminal (domain) [191-256]
- IPR044492: P-type ATPase, haloacid dehalogenase domain (domain) [551-1016]
- IPR006539: P-type ATPase, subfamily IV (family) [203-1252]
- IPR008250: P-type ATPase, A domain superfamily (homologous_superfamily) [296-439]
- IPR023299: P-type ATPase, cytoplasmic domain N (homologous_superfamily) [574-817]
- IPR032630: P-type ATPase, C-terminal (domain) [993-1245]
- IPR018303: P-type ATPase, phosphorylation site (ptm) [569-575]
- IPR001757: P-type ATPase (family) [937-1047]
- IPR023298: P-type ATPase, transmembrane domain superfamily (homologous_superfamily) [171-1244]
Interaction partners: - Aminophospholipid translocase regulatory protein
- Lem3p
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0140657 (ATP-dependent activity), GO:0140326 (ATPase-coupled intramembrane lipid transporter activity), GO:0005319 (lipid transporter activity), GO:0140303 (intramembrane lipid transporter activity), GO:0140327 (flippase activity), GO:0005548 (phospholipid transporter activity), GO:0140333 (glycerophospholipid flippase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0051234 (establishment of localization), GO:0030447 (filamentous growth), GO:0051641 (cellular localization), GO:0009628 (response to abiotic stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0006950 (response to stress), GO:0071554 (cell wall organization or biogenesis), GO:0051649 (establishment of localization in cell), GO:0016043 (cellular component organization), GO:0044182 (filamentous growth of a population of unicellular organisms), GO:0071852 (fungal-type cell wall organization or biogenesis), GO:0036180 (filamentous growth of a population of unicellular organisms in response to biotic stimulus), GO:0071555 (cell wall organization), GO:0006810 (transport), GO:0031505 (fungal-type cell wall organization), GO:0045229 (external encapsulating structure organization), GO:0006811 (monoatomic ion transport), GO:0006812 (monoatomic cation transport), GO:0030001 (metal ion transport), GO:0000041 (transition metal ion transport), GO:0006826 (iron ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)