Protein: adenylate cyclase (EC 4.6.1.1) (G0TC75)
Organism: Bos taurus (Bovine)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MAVLYKYPVLDCEVEDHVAFLITVPTALAIFFAIFTLVCVESVFKKLLRLFSLVIWICLVAMGYLFMCFGGTVSPWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTSSSHTIVLSVCLSATPGAKEHLVWQILANVVIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFEKRQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTPANHMEAGGVPGRVHISSVTLQHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGERRSPQHLFRPRHTLDGAKMRASVRMTRYLESWGAAKPYAHLHHRDSMTTENGKISTTDVPMGQHNFQNRTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKIIEKEYRATALPAFKYYVTCACLIFFCIFIVQVLVLPKTSILGISFGAAFLSLAFILFVCFAGQLLQCSKKASASLLWLLKSSGIIANRPWPRISLTVITTAIILTMAVFNMFFLSDSEETILPTANASNTSLSGASNQAAIPRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMAALVGYNTIFLHTHAPLLDDYSQVLFERPGIWKDLKTMGSVSLFIFFITLLVLGRQNEYYCRLDFLWKNKFKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIPDFKEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQEHAQEPERQYMHIGTMVEFAFALVGKLDAINKHSFNGFKLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKI
InterPro domains: - IPR018297: Adenylyl cyclase class-4/guanylyl cyclase, conserved site (conserved_site) [336-974]
- IPR009398: Adenylate cyclase, conserved domain (domain) [437-542]
- IPR030672: Adenylate cyclase (family) [1-982]
- IPR029787: Nucleotide cyclase (homologous_superfamily) [169-982]
- IPR001054: Adenylyl cyclase class-3/4/guanylyl cyclase (domain) [177-982]
- IPR032628: Adenylate cyclase, N-terminal (domain) [17-203]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0016829 (lyase activity), GO:0009975 (cyclase activity), GO:0004016 (adenylate cyclase activity), GO:0016849 (phosphorus-oxygen lyase activity), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0000287 (magnesium ion binding), GO:0046914 (transition metal ion binding), GO:0030145 (manganese ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050789 (regulation of biological process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0042221 (response to chemical), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0035556 (intracellular signal transduction), GO:0046483 (heterocycle metabolic process), GO:0019637 (organophosphate metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901700 (response to oxygen-containing compound), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0010033 (response to organic substance), GO:1901135 (carbohydrate derivative metabolic process), GO:0006793 (phosphorus metabolic process), GO:0010035 (response to inorganic substance), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0007186 (G protein-coupled receptor signaling pathway), GO:1902074 (response to salt), GO:0010038 (response to metal ion), GO:0097305 (response to alcohol), GO:1901362 (organic cyclic compound biosynthetic process), GO:0006753 (nucleoside phosphate metabolic process), GO:1901654 (response to ketone), GO:0071310 (cellular response to organic substance), GO:0019438 (aromatic compound biosynthetic process), GO:1902075 (cellular response to salt), GO:0006796 (phosphate-containing compound metabolic process), GO:0072521 (purine-containing compound metabolic process), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0019932 (second-messenger-mediated signaling), GO:1901566 (organonitrogen compound biosynthetic process), GO:0051592 (response to calcium ion), GO:0071241 (cellular response to inorganic substance), GO:0033993 (response to lipid), GO:0019693 (ribose phosphate metabolic process), GO:0018130 (heterocycle biosynthetic process), GO:0090407 (organophosphate biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0014070 (response to organic cyclic compound), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0007188 (adenylate cyclase-modulating G protein-coupled receptor signaling pathway), GO:1901701 (cellular response to oxygen-containing compound), GO:1901655 (cellular response to ketone), GO:0009117 (nucleotide metabolic process), GO:0071277 (cellular response to calcium ion), GO:1901293 (nucleoside phosphate biosynthetic process), GO:0019935 (cyclic-nucleotide-mediated signaling), GO:0071407 (cellular response to organic cyclic compound), GO:0071396 (cellular response to lipid), GO:0009259 (ribonucleotide metabolic process), GO:0071248 (cellular response to metal ion), GO:0046390 (ribose phosphate biosynthetic process), GO:0007189 (adenylate cyclase-activating G protein-coupled receptor signaling pathway), GO:0006163 (purine nucleotide metabolic process), GO:0072522 (purine-containing compound biosynthetic process), GO:0097306 (cellular response to alcohol), GO:1904321 (response to forskolin), GO:0019933 (cAMP-mediated signaling), GO:0009150 (purine ribonucleotide metabolic process), GO:0009260 (ribonucleotide biosynthetic process), GO:0009187 (cyclic nucleotide metabolic process), GO:1904322 (cellular response to forskolin), GO:0052652 (cyclic purine nucleotide metabolic process), GO:0009165 (nucleotide biosynthetic process), GO:0006164 (purine nucleotide biosynthetic process), GO:0046058 (cAMP metabolic process), GO:0009190 (cyclic nucleotide biosynthetic process), GO:0009152 (purine ribonucleotide biosynthetic process), GO:0006171 (cAMP biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)