wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Inositol polyphosphate-5-phosphatase A (EC 3.1.3.56) (Type I inositol 1,4,5-trisphosphate 5-phosphatase) (5PTase) (Q7TNC9)
Organism: Mus musculus (Mouse)
Function: Phosphatase that specifically hydrolyzes the 5-phosphate of inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate, and inositol 1,3,4,5-tetrasphosphate to inositol 1,3,4-trisphosphate. Plays a crucial role in the survival of cerebellar Purkinje cells.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q14642}; Lipid-anchor {ECO:0000250|UniProtKB:Q14642}. Cell projection, dendrite {ECO:0000269|PubMed:26051944}.
Sequence: MAGKAAAPGTAVLLVTANVGSLFDDPENLQKNWLREFYQVLHTHKPHFMALHCQEFGGKNYEASMSHVDKFVKELLSSDAMKEYNRARVYLDENYKSQEHFTALGSFYFLHESLKNIYQFDFKAKKYKKVTGKEIYSDTLESTPMLEKEKFPQDYFPECKWSRKGFIRTRWCIADCAFDLVNIHLFHDASNLVAWETSPSVYSGVRHKALGYVLDRIIDQRFEKVSYFVFGDFNFRLDSKSVVETLCTKATMQTVRAADTNEVVKLIFRESDNDRKVVLQLEKKLFDYFNQDVFRDNNGTALLEFDKELSVFKDRLYELDISFPPSYPYSEDSSQGEQYMNTRCPAWCDRILMSLSAKELVLKSESEEKVATYDHIGPNVCMGDHKPVFLAFRIAPGAGKPHAHVHKCCVVQ
InterPro domains: - IPR036691: Endonuclease/exonuclease/phosphatase superfamily (homologous_superfamily) [6-407]
- IPR039737: Type I inositol 1,4,5-trisphosphate 5-phosphatase (family) [6-406]
- IPR000300: Inositol polyphosphate-related phosphatase (domain) [8-400]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0016791 (phosphatase activity), GO:0052745 (inositol phosphate phosphatase activity), GO:0046030 (inositol trisphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:0006066 (alcohol metabolic process), GO:0005975 (carbohydrate metabolic process), GO:0044262 (cellular carbohydrate metabolic process), GO:0006793 (phosphorus metabolic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0006020 (inositol metabolic process), GO:0019751 (polyol metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: T-cell acute lymphocytic leukemia 2 (T-cell acute lymphocytic leukemia protein 2) (F1QUD8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Sequence: MTRKVFTNTRERWRQHNVNTAFAELRKLIPTHPPEKKLSKNEILRLAMRYINFLVTLLESQGGEPSAHSQAALLTLLTGNMQNLRTDRTWTSDTDPPSPGSSCDSSEAW
InterPro domains: - IPR011598: Myc-type, basic helix-loop-helix (bHLH) domain (domain) [2-60]
- IPR040238: Helix-loop-helix protein TAL-like (family) [1-106]
- IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [1-72]
Interaction partners: - Rhombotin-2
- Rhombotin-1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding), GO:0000987 (cis-regulatory region sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0001944 (vasculature development), GO:0072359 (circulatory system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Pyridoxal kinase (EC 2.7.1.35) (Pyridoxine kinase) (Q55EK9)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Required for synthesis of pyridoxal-5-phosphate from vitamin B6.
Subcellular location: Cytoplasm {ECO:0000250}.
Sequence: MEPKVLSIQSWVCHGYVGNKCAVFALQHLGIEVDPINSVHLSNNTAYPTWKGESLTPNKLGDLFQGLEDNHLTSNYTHVLTGYNNSVQTLHTVLKIVKKLKSENPNLIYVCDPVLGDNNELYVPEDLVEVYKNEVIPNADYIFPNQTEVEFLTGIKIKNDQDALKAIDQFHKMGVKNVVITSLFFDTNPNDIIVIGSTINDDDNNNKYNQFKIKVGPKFNDYYTGTGDLLSSLLLGWSIREPTDLSLVCEKAISILYNIINETHNSKKSIPSNKEKQYYELRLVQSRKFIENSEIRFKSEKL
InterPro domains: - IPR013749: Pyridoxamine kinase/Phosphomethylpyrimidine kinase (domain) [92-262]
- IPR029056: Ribokinase-like (homologous_superfamily) [1-301]
- IPR004625: Pyridoxine kinase (family) [2-301]
Interaction partners: - Pyridoxine-5'-phosphate oxidase
- Probable pyridoxal 5'-phosphate synthase subunit pdx2
- Probable pyridoxal 5'-phosphate synthase subunit pdx1
- Proliferating cell nuclear antigen
- Pyridoxal phosphate homeostasis protein
- 2Fe-2S ferredoxin-type domain-containing protein
- Metalloenzyme domain-containing protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:1901700 (response to oxygen-containing compound), GO:0070887 (cellular response to chemical stimulus), GO:0009743 (response to carbohydrate), GO:0071310 (cellular response to organic substance), GO:1901701 (cellular response to oxygen-containing compound), GO:0071322 (cellular response to carbohydrate stimulus), GO:0034284 (response to monosaccharide), GO:0071326 (cellular response to monosaccharide stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Uncharacterized protein (F4JCB3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MQQIEKRSLLCSFLSVFHLIHLQALLLEMAELRSGVLFKLLEEMGVGKVRRDVDHRPVLLQIRCIIPVLAAGGLWPNKGFFLRITDSTHSIYVSLPREENDLVLYDKLQIGQLIFVEKLEFAYPVPMIKGIRPTPGRRACTGDPIDLIPKERIEKFCVGLSDIEENYDHQVKKPRRTRWNNSSVSELNFTDLGLSKNLSSVMEEKDDTESMISSCSSSFSSAARRRSWIGSADNRKRRDSLDPSMIKNHDHDTKHVSRARSSSATSPSLSIRSYGGIEEKSSSRTRRRDVVVSPSPRWSKSLSYGSRSNKSKNLLPPKSNTFESSDPISRKRSWTETEILWDSLPPKVVNLGKEILRQRDTAIRAASQALLEASAAERLLKCLRSYSELSDRRNQHQENQQPPIQDFLSFQDELSKSRLIIQSLSTEKTEHCNANIVKTGDERREKATQWIKSALATDLKLVSLSASKPTQSPGRKGLTLIAQESDNREGNASESNSRLGEIKERLSRASSELRNWLKEEGRSWYLNRVEKYLDEISNGTKWREMRSEEVGETMYQIKRVSDWLDTIVKGEEDEEEKMVMMMMSESETEACGRVRNKIYRILLKHVETTSLLSHQRSTSLMSHHQQQQHEQHLFQKTMSL
InterPro domains: - IPR048297: Domain of unknown function DUF936, plants (domain) [32-148]
- IPR010341: Protein of unknown function DUF936, plants (family) [29-609]
- IPR049172: Domain of unknown function DUF6857, plants (domain) [329-610]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0015631 (tubulin binding), GO:0008017 (microtubule binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0007389 (pattern specification process), GO:0003002 (regionalization), GO:0010051 (xylem and phloem pattern formation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0099513 (polymeric cytoskeletal fiber), GO:0005874 (microtubule), GO:0015630 (microtubule cytoskeleton)
Protein: Glutamate decarboxylase (EC 4.1.1.15) (Q6FS86)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Function: Not known
Sequence: MLHKHTDKQRLPVNIVDHHHIDPCLQDFKLLSKELQDIASNSEKLKALGSKENKESHLLSMKYVIPKEGVPADQAYDMIHNELTLDGNTHLNLASFVNTSTTHEVRKLISENLTKNLADNDEYPQLIELTQRCISMLSGLWNANPEEEPIGCATTGSSEAIMLGGLAMKKMWEKKMKAAGRTDTSKPNIIMSSACQVALEKFARYFDVECRLVPVSRKSHHMLDPNLLWDFVDENTIGCFVIMGTTYTGHLENVAEVGDVLTAIEKQHPEWANKDIPIHVDGASGGFIVPFAFSREQLKAYGVPNWGFDHPRVVSINTSGHKFGLTTPGLGWVLWRDESHLAPELRFRLKYLGGVEETFGLNFSRPGFQVVHQYYNFMNLGYDGYRDTFKRSLFVARVFAHQILRSPIFNDYFEVVSSIHESIDGDKVPDAANDYWENPEKYKPGVPLIAFKFSDKFQKEYPEVPQALLSHMLRTRGWIIPNYPLPHSTDGSDKCEVLRVVFRNEMSLDLAQLLLSDIQAVLRKLQGSYSGLKTISHESDSDKRRDYVYKMLLALASPDADIGEDEDEETKEKKASKKEEIKQRLKRNYRGTC
InterPro domains: - IPR015421: Pyridoxal phosphate-dependent transferase, major domain (homologous_superfamily) [99-404]
- IPR010107: Glutamate decarboxylase (family) [60-580]
- IPR002129: Pyridoxal phosphate-dependent decarboxylase (family) [77-409]
- IPR015424: Pyridoxal phosphate-dependent transferase (homologous_superfamily) [57-525]
Interaction partners: - 4-aminobutyrate aminotransferase
- NAD-specific glutamate dehydrogenase
- Candida glabrata strain CBS138 chromosome F complete sequence
- Multifunctional fusion protein
- Glutamate dehydrogenase
- Pantoate--beta-alanine ligase
- Candida glabrata strain CBS138 chromosome D complete sequence
- Aldehyde dehydrogenase
- Aldehyde dehydrogenase 5
- Candida glabrata strain CBS138 chromosome H complete sequence
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016830 (carbon-carbon lyase activity), GO:0016831 (carboxy-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006520 (amino acid metabolic process), GO:0043603 (amide metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006082 (organic acid metabolic process), GO:0006536 (glutamate metabolic process), GO:0043436 (oxoacid metabolic process), GO:1901605 (alpha-amino acid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0009064 (glutamine family amino acid metabolic process), GO:0043648 (dicarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Protein ERGIC-53 (ER-Golgi intermediate compartment 53 kDa protein) (Lectin mannose-binding 1) (p58) (Q9D0F3)
Organism: Mus musculus (Mouse)
Function: Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins (By similarity).
Subcellular location: Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Sequence: MAVSRRRVPQAGARSFFCALLLSFSQFTGSDGTGGDAAAPGAAGTQAELPHRRFEYKYSFKGPHLVQSDGTVPFWAHAGNAIPSADQIRIAPSLKSQRGSVWTKAKAAFENWEVEVTFRVTGRGRIGADGLAIWYTENQGLDGPVFGSADTWNGVGIFFDSFDNDGKKNNPAIVVIGNNGQINYDHQNDGATQALASCQRDFRNKPYPVRAKITYYQKTLTVMINNGFTPDKNDYEFCAKVENMVIPTQGHFGISAATGGLADDHDVLSFLTFQLTEPGKEPPTAEKDISEKEKEKYQEEFEHFQQELDKKKEEFQKGHPDLQGQPADDIFESIGDRELRQVFEGQNRIHLEIKQLNRQLDMILDEQRRYVSSLTEEISRRGAGTPGQPGQVSQQELDTVVKSQQEILRQVNEVKNSMSETVRLVSGIQHPGSAGVYETTQHFMDIKEHLHVVKRDIDSLAQRSMPSNEKPKCPDLPPFPSCLSTIHFVIFVVVQTVLFVGYIMYRTQQEAAAKKFF
InterPro domains: - IPR005052: Legume-like lectin (domain) [52-276]
- IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [50-277]
- IPR051136: Intracellular Lectin and Glycoprotein Transporter (family) [35-511]
Interaction partners: - Multiple coagulation factor deficiency protein 2 homolog
- Protein transport protein Sec31A
- Protein transport protein Sec23A
- Endoplasmic reticulum resident protein 44
- Vesicle-trafficking protein SEC22b
- Protein SEC13 homolog
- SEC24 homolog C, COPII coat complex component
- Calnexin
- Coatomer subunit beta
- SEC24 homolog B, COPII coat complex component)
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0046907 (intracellular transport), GO:0051649 (establishment of localization in cell), GO:0006810 (transport), GO:0006888 (endoplasmic reticulum to Golgi vesicle-mediated transport), GO:0016192 (vesicle-mediated transport), GO:0048193 (Golgi vesicle transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005793 (endoplasmic reticulum-Golgi intermediate compartment), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Sporulation-specific protein 12 (P17123)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: It is required for meiosis I chromosome division during sporulation. A component of the FEAR (CDC14 early anaphase release) network which promotes CDC14 release from the nucleolus during early anaphase.
Sequence: MSNKASDQSARTASILKTDITRENTITRSSSSNNDNYHHHNNINNYNESAKTGEDANKENIPNLEEEIAAFRIFRKKSTSNLKSSHTTSNLVKKTMFKRDLLKQDPKRKLQLQQRFASPTDRLVSPCSLKLNEHKVKMFGKKKKVNPMKLNFKGNLAADSEDVEIDEDEEYFY
InterPro domains: - IPR007727: Spo12 (family) [117-152]
Interaction partners: - Cell cycle protein kinase DBF2
- Tyrosine-protein phosphatase CDC14
- Separin
- Cell cycle serine/threonine-protein kinase CDC5/MSD2
- Kinetochore protein SLK19
- Guanine nucleotide exchange factor LTE1
- Protein TEM1
- Securin
- G2/mitotic-specific cyclin-2
- Cell division control protein 15
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0000003 (reproduction), GO:0022414 (reproductive process), GO:0051321 (meiotic cell cycle), GO:0048523 (negative regulation of cellular process), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0007049 (cell cycle), GO:1903828 (negative regulation of protein localization), GO:0060341 (regulation of cellular localization), GO:0032880 (regulation of protein localization), GO:1900181 (negative regulation of protein localization to nucleus), GO:1900180 (regulation of protein localization to nucleus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Pyridoxal-phosphate-dependent serine hydroxymethyltransferase, putative (DUF632) (F4J3B3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MGCCQSRIDSKEIVSRCKARKRYLKHLVKARQTLSVSHALYLRSLRAVGSSLVHFSSKETPLHLHHNPPSPSPPPPPPPRPPPPPLSPGSETTTWTTTTTSSVLPPPPPPPPPPPPPSSTWDFWDPFIPPPPSSSEEEWEEETTTATRTATGTGSDAAVTTAPTTATPQASSVVSGFSKDTMTTTTTGSELAVVVSRNGKDLMEIIKEVDEYFLKAADSGAPLSSLLEISTSITDFSGHSKSGKMYSSSNYECNLNPTSFWTRGFAPSKLSEYRNAGGVIGGNCIVGSHSSTVDRLYAWEKKLYQEVKYAESIKMDHEKKVEQVRRLEMKRAEYVKTEKAKKDVEKLESQLSVSSQAIQSASNEIIKLRETELYPQLVELVKGSMYESHQVQTHIVQQLKYLNTIPSTEPTSELHRQSTLQLELEVQQWHHSFCNLVKAQRDYIQSLTGWLRLSLFQFSKNPLVRSSYESKIYSFCEEWHLAIDRIPDKVASEGIKSFLTAVHGIVAQQADEHKQKKRTESMLKDFEKKSASLRALESKYSPYSVPESRKKNPVIEKRVKVEMLKGKAEEEKSKHEKSVSVTRAMTLNNLQMGFPHVFQAMVGFSSVCMQAFESVYNQAKSIGEDQEEVKRLLP
InterPro domains: - IPR006867: Domain of unknown function DUF632 (domain) [202-503]
- IPR006868: Domain of unknown function DUF630 (domain) [1-59]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0051234 (establishment of localization), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0001666 (response to hypoxia), GO:0006810 (transport), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0070482 (response to oxygen levels), GO:0071456 (cellular response to hypoxia), GO:0071702 (organic substance transport), GO:0071453 (cellular response to oxygen levels), GO:0036293 (response to decreased oxygen levels), GO:0036294 (cellular response to decreased oxygen levels), GO:0015849 (organic acid transport), GO:0015711 (organic anion transport), GO:0046942 (carboxylic acid transport), GO:0015718 (monocarboxylic acid transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Probable metabolite transport protein YFL040W (P43562)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Not known
Subcellular location: Membrane; Multi-pass membrane protein.
Sequence: MTAMKAIVWRLPKMPKIKITKTYEVTKITAILTLVGFIMGLEVPSLATFLTNKTFNEYFKYPTPLQQGLLMGSTPLGGIMGCFICCIMNDRFSRIYQFQSGIIIWNIVTLLNFCIWDILGLLICRMIKGMILGNFSILVASYANEVIPRGKRGSTMSYIQLCLTIGILVMHYLCIALSLWDSHFAFRIAWCIGIIPGLLFWMASYALPESYHWLVLHGKMSEAQEIQHNLAKKFNESQPRDAVPEMSKIELAGDFWIGVNDLDFSKKLPRGSFKPLILGMTLQLLVQFSGINIILGYITYICEIVGLEGNVKLFTSSIPYFINMVLSLLPITFIDYTSRKLITLLGGFPISGLLITIGALFVKYGQDTKPIDGNRSLVWSIGENPFVGGWILTLCFLIVGIFAMSLSSIPWVYTNEMLPSRVKVKGFAICVTFGWLGNFILTFLCPVMIERLKGTTFIIFGSLTFLISLSVLIWFPETKGMSIEDIDKFFEFESKEGTNLHGEKGIKTPDSNSNGGSTRSSQEGQLHKPIKLKSDEEMII
InterPro domains: - IPR036259: MFS transporter superfamily (homologous_superfamily) [20-492]
- IPR020846: Major facilitator superfamily domain (domain) [28-479]
- IPR005829: Sugar transporter, conserved site (conserved_site) [127-152]
- IPR050360: Major Facilitator Superfamily Sugar Transporters (family) [21-499]
- IPR005828: Major facilitator, sugar transporter-like (family) [43-490]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015144 (carbohydrate transmembrane transporter activity), GO:0051119 (sugar transmembrane transporter activity), GO:0015145 (monosaccharide transmembrane transporter activity), GO:0015149 (hexose transmembrane transporter activity), GO:0015578 (mannose transmembrane transporter activity), GO:0005355 (glucose transmembrane transporter activity), GO:0005353 (fructose transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0034219 (carbohydrate transmembrane transport), GO:0006810 (transport), GO:0015749 (monosaccharide transmembrane transport), GO:0071702 (organic substance transport), GO:0008645 (hexose transmembrane transport), GO:0008643 (carbohydrate transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0005773 (vacuole), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0000322 (storage vacuole), GO:0000324 (fungal-type vacuole)
Protein: Cyclotide hyen-J (C0HLP4)
Organism: Pigea enneasperma (Spade flower) (Afrohybanthus enneaspermus)
Function: Probably participates in a plant defense mechanism.
Sequence: GSVPCGESCVWIPCITSIAGCSCSNKVCYMD
InterPro domains: - IPR012323: Cyclotide, bracelet, conserved site (conserved_site) [5-14]
- IPR036146: Cyclotide superfamily (homologous_superfamily) [5-31]
- IPR005535: Cyclotide (family) [1-31]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0090729 (toxin activity), GO:0016247 (channel regulator activity), GO:0140678 (molecular function inhibitor activity), GO:0016248 (channel inhibitor activity), GO:0099106 (ion channel regulator activity), GO:0008200 (ion channel inhibitor activity), GO:0015459 (potassium channel regulator activity), GO:0019870 (potassium channel inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0001906 (cell killing), GO:0006950 (response to stress), GO:0031640 (killing of cells of another organism), GO:0019835 (cytolysis), GO:0006952 (defense response), GO:0051715 (cytolysis in another organism)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)