Protein: Formin-like 2a (F1QKR1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MGNAGSMNQHTDPRGHHMPLKLPMPEPAELEERFALVLNSMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPHTYIHKLQSYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLSFAQYAVTYDGDSSENSTENSVDKSKAWSRSIEDLHGGNHLSSGGSGSNISRTNRHSTIRSNTLPSRRTLKNSRLVCKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDHFKEVCLEEQRFEKLMEYFKNEDNNIDFMVACMQFINIVVHSVEDMNFRVHLQYDFTKLGLDEYLDKLKHTESDKLHVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENMSHLTEKLQDTENEAMAKIVELEKQLMQRNKELDSLRDVYKDANSQVHTLRRMVKEKDEAIQRQCNLEKKIHELEKQGTIKIQKKGDGDIAILTSPPQGNGHLTGSESITGVPSGGVVSHGGVANGVAHGVHIPDPSLPLPPPSSSVSETVLNGPSAAPAPAPPPPPPPPPPPLPVDISAPMPPPPPPMAPPLPGCGSPTVIMNSGLAAVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEMFKTKAQGPAIDITSSKQKTAQKGPHKISLLDANRSKNLAITLRKVGKTSEEICRGIQLFDLRTLPVDFVECLMRFIPSEAELKVLRQYEKERKPLENLTDEDRFMIQFSKIERLMQKMTIMAFVGNFTESIQMLTPQLHAVIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKITLLHYIANVVKDKYQQVSLFYNELNYVEKAAAVSLENVLLDVKELQRGMDLTRKEYSMHGHNTLLKDFIQQNENKLKKLQDDAKIAQDAFDEVVKFFGENAKTTPPSVFFPVFVRFVKAYRQAEEDNEQKKRHEQMMMEKLIEQEAMEQEDQKSPSHKNKRQQQELIAELRKKQVKDSRHVYEGKDGAIEDIITVLKTVPFTARTAKRSSRYFNEELHF
InterPro domains: - IPR015425: Formin, FH2 domain (domain) [613-1049]
- IPR010472: Formin, FH3 domain (domain) [278-473]
- IPR014768: Rho GTPase-binding/formin homology 3 (GBD/FH3) domain (domain) [22-459]
- IPR043592: Formin-like protein, animal (family) [7-1073]
- IPR016024: Armadillo-type fold (homologous_superfamily) [30-451]
- IPR011989: Armadillo-like helical (homologous_superfamily) [22-377]
- IPR014767: Diaphanous autoregulatory domain (domain) [1035-1072]
- IPR010473: Formin, GTPase-binding domain (domain) [22-275]
- IPR042201: Formin, FH2 domain superfamily (homologous_superfamily) [606-991]
Interaction partners: - BAG family molecular chaperone regulator 4
- Cell division cycle 42-like 2
- E2F transcription factor 5
- Rho-related GTP-binding protein RhoA-D
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0071840 (cellular component organization or biogenesis), GO:0030029 (actin filament-based process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0035239 (tube morphogenesis), GO:0044085 (cellular component biogenesis), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0016043 (cellular component organization), GO:0030036 (actin cytoskeleton organization), GO:0030030 (cell projection organization), GO:0048514 (blood vessel morphogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0043933 (protein-containing complex organization), GO:0006996 (organelle organization), GO:0002040 (sprouting angiogenesis), GO:0097435 (supramolecular fiber organization), GO:0007015 (actin filament organization), GO:0022607 (cellular component assembly), GO:0007010 (cytoskeleton organization), GO:0065003 (protein-containing complex assembly), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0008154 (actin polymerization or depolymerization), GO:0051258 (protein polymerization), GO:0120031 (plasma membrane bounded cell projection assembly), GO:0030041 (actin filament polymerization), GO:0046847 (filopodium assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)