Protein: Protein FMC1 homolog (ATP synthase assembly factor FMC1, mitochondrial) (Formation of mitochondrial complex V assembly factor 1 homolog) (Q96HJ9)
Organism: Homo sapiens (Human)
Function: Plays a role in the assembly/stability of the mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V).
Subcellular location: Mitochondrion {ECO:0000269|PubMed:28719601}.
Sequence: MAALGSPSHTFRGLLRELRYLSAATGRPYRDTAAYRYLVKAFRAHRVTSEKLCRAQHELHFQAATYLCLLRSIRKHVALHQEFHGKGERSVEESAGLVGLKLPHQPGGKGWEP
InterPro domains: - IPR037667: Protein FMC1 homologue (family) [1-113]
Interaction partners: - ATP synthase mitochondrial F1 complex assembly factor 2
- GrpE protein homolog 2, mitochondrial
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0065009 (regulation of molecular function), GO:0048523 (negative regulation of cellular process), GO:0009892 (negative regulation of metabolic process), GO:0009894 (regulation of catabolic process), GO:0050790 (regulation of catalytic activity), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0044092 (negative regulation of molecular function), GO:0062012 (regulation of small molecule metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0062014 (negative regulation of small molecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0009895 (negative regulation of catabolic process), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0006140 (regulation of nucleotide metabolic process), GO:0043086 (negative regulation of catalytic activity), GO:0043470 (regulation of carbohydrate catabolic process), GO:0045980 (negative regulation of nucleotide metabolic process), GO:0045820 (negative regulation of glycolytic process), GO:0010563 (negative regulation of phosphorus metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:0051174 (regulation of phosphorus metabolic process), GO:1900542 (regulation of purine nucleotide metabolic process), GO:0006110 (regulation of glycolytic process), GO:1900543 (negative regulation of purine nucleotide metabolic process), GO:0045936 (negative regulation of phosphate metabolic process), GO:0019220 (regulation of phosphate metabolic process), GO:0042325 (regulation of phosphorylation), GO:1903578 (regulation of ATP metabolic process), GO:0033673 (negative regulation of kinase activity), GO:0042326 (negative regulation of phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)