Protein: Diacylglycerol kinase (DAG kinase) (EC 2.7.1.107) (Q17860)
Organism: Caenorhabditis elegans
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Sequence: MAAEGHNVDANLVDMRPNHGHYFVKKTFGKPAYCHHCCDKIWGMLTTGYSCEMCNFVCHEKCLRTVVSYCSSVALQLIKNPVAHTWSAPCLIKRKYCCVCRKRTDDALSVECEVCEYYVHVDCSDLAVSDCKEAATYVANMESANTVQYHHMREGNLPKESKCIVCRKTCFSTECLAGMRCEWCGQTAHAVCYRQMDKECDFGVLRKIMLPPMCLTIPRTELPMEQLLNISSHDQPQSRKVSSPSKIQADDVSTSGEDVKEREDFEIIRVFDGNNSYRSQISRNIVVAKHVSVQQVRDAALRRFHINDTPERYYITQVVGEVEEEILEDPVPLRNVKRPEGKRAQIFIRYYDDPDKDEVKVYGGWLRKVPVTFCAISVSKDTVVQDLVTDALYHFGLDGSCWNRYNLIEVSLDRGVAERTCNPQENVLQLVRNLRKDSLRRYHVVRFYVQEKEDPHDHAVFVGNLPVSLAQRQYERILLKLLGAKEKPFTAIGPIYFEYGSLIITFNTPKAATAAVQKLQSAIYEEKKLIVLCLPNVQPQMIPKDVEPLLVLVNVKSGGCQGTELIQSFRKLLNPFQVFDVLNGGPLVGLYVFRNIPKYKILACGGDGTIGWVLQCLDIAKQDAACFSPPCGIVPLGTGNDLARVLRWGGGYTGEENPMDILKDVIEADTVKLDRWAVVFHEEERNQPTSSGNQTEMNEQTMNNPEDQTSMIIMNNYFGIGIDADVCLKFHNKRDANPEKFQSRLFNKTQYAKIGLQKMFFERTCKDLWKRIELEVDGRIIELPNIEGIVVLNLLSWGSGANPWGTSKEEGNFSKPTHYDGLLEVVGISDVSRLGLIQSKLAAGIRIAQGGSIRITTHEEWPVQVDGEPHIQPPGTITILKSALKAQMLKKAKKSRRGGATNATSLTHPHPETSESMSGPLGVPSTLGDPNHGKTTPDNTAADSDEEGDAFL
InterPro domains: - IPR046349: C1-like domain superfamily (homologous_superfamily) [11-205]
- IPR029071: Ubiquitin-like domain superfamily (homologous_superfamily) [265-454]
- IPR020454: Diacylglycerol/phorbol-ester binding (domain) [18-71]
- IPR001206: Diacylglycerol kinase, catalytic domain (domain) [544-682]
- IPR002219: Protein kinase C-like, phorbol ester/diacylglycerol-binding domain (domain) [20-202]
- IPR000159: Ras-associating domain (domain) [264-454]
- IPR000756: Diacylglycerol kinase, accessory domain (domain) [713-869]
- IPR017438: Inorganic polyphosphate/ATP-NAD kinase, N-terminal (homologous_superfamily) [545-688]
- IPR056392: Diacylglycerol kinase theta, RNA-binding domain (domain) [460-535]
- IPR016064: NAD kinase/diacylglycerol kinase-like domain superfamily (homologous_superfamily) [548-886]
- IPR037607: Diacylglycerol kinase (family) [81-897]
- IPR001965: Zinc finger, PHD-type (domain) [96-167]
Interaction partners: - Guanine nucleotide-binding protein G
- Regulator of G-protein signaling 7
- Guanine nucleotide-binding protein subunit alpha
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta egl-8
- Phorbol ester/diacylglycerol-binding protein unc-13
- Regulator of G-protein signaling egl-10
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0051020 (GTPase binding), GO:0016301 (kinase activity), GO:0031267 (small GTPase binding), GO:0004143 (diacylglycerol kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050789 (regulation of biological process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:2000241 (regulation of reproductive process), GO:0051239 (regulation of multicellular organismal process), GO:0071704 (organic substance metabolic process), GO:0007267 (cell-cell signaling), GO:0044237 (cellular metabolic process), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0040013 (negative regulation of locomotion), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0044238 (primary metabolic process), GO:0040012 (regulation of locomotion), GO:0032094 (response to food), GO:0044255 (cellular lipid metabolic process), GO:0071495 (cellular response to endogenous stimulus), GO:1901700 (response to oxygen-containing compound), GO:0007210 (serotonin receptor signaling pathway), GO:0010033 (response to organic substance), GO:0006793 (phosphorus metabolic process), GO:0009991 (response to extracellular stimulus), GO:0099536 (synaptic signaling), GO:0006629 (lipid metabolic process), GO:1901698 (response to nitrogen compound), GO:0046662 (regulation of oviposition), GO:0070887 (cellular response to chemical stimulus), GO:0050795 (regulation of behavior), GO:0007212 (dopamine receptor signaling pathway), GO:0071417 (cellular response to organonitrogen compound), GO:0071310 (cellular response to organic substance), GO:1901699 (cellular response to nitrogen compound), GO:0006796 (phosphate-containing compound metabolic process), GO:0071869 (response to catecholamine), GO:0010243 (response to organonitrogen compound), GO:0031667 (response to nutrient levels), GO:0099537 (trans-synaptic signaling), GO:0030258 (lipid modification), GO:0014070 (response to organic cyclic compound), GO:1901701 (cellular response to oxygen-containing compound), GO:0071870 (cellular response to catecholamine stimulus), GO:0046834 (lipid phosphorylation), GO:1903350 (response to dopamine), GO:0071868 (cellular response to monoamine stimulus), GO:0071407 (cellular response to organic cyclic compound), GO:0016310 (phosphorylation), GO:0071867 (response to monoamine), GO:0098916 (anterograde trans-synaptic signaling), GO:0007268 (chemical synaptic transmission), GO:1903351 (cellular response to dopamine), GO:0007271 (synaptic transmission, cholinergic)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0048471 (perinuclear region of cytoplasm), GO:0005737 (cytoplasm), GO:0042995 (cell projection), GO:0044297 (cell body), GO:0120025 (plasma membrane bounded cell projection), GO:0043005 (neuron projection), GO:0030424 (axon)