Protein: Probable ribonucleotide transport ATP-binding protein mkl (P9WQL5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Not known, could be involved in the transport of ribonucleotides.
Sequence: MRYSDSYHTTGRWQPRASTEGFPMGVSIEVNGLTKSFGSSRIWEDVTLTIPAGEVSVLLGPSGTGKSVFLKSLIGLLRPERGSIIIDGTDIIECSAKELYEIRTLFGVLFQDGALFGSMNLYDNTAFPLREHTKKKESEIRDIVMEKLALVGLGGDEKKFPGEISGGMRKRAGLARALVLDPQIILCDEPDSGLDPVRTAYLSQLIMDINAQIDATILIVTHNINIARTVPDNMGMLFRKHLVMFGPREVLLTSDEPVVRQFLNGRRIGPIGMSEEKDEATMAEEQALLDAGHHAGGVEEIEGVPPQISATPGMPERKAVARRQARVREMLHTLPKKAQAAILDDLEGTHKYAVHEIGQ
InterPro domains: - IPR003439: ABC transporter-like, ATP-binding domain (domain) [28-264]
- IPR003593: AAA+ ATPase domain (domain) [52-248]
- IPR017871: ABC transporter-like, conserved site (conserved_site) [164-178]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [26-341]
Interaction partners: - Conserved integral membrane protein YrbE1B
- Conserved integral membrane protein YrbE1A
- Conserved hypothetical integral membrane protein YrbE3A
- Conserved hypothetical integral membrane protein YrbE2B
- Conserved integral membrane protein YrbE4B. Possible ABC transporter
- Conserved hypothetical integral membrane protein YrbE3B
- Conserved integral membrane protein YrbE4A. Possible ABC transporter
- Conserved hypothetical integral membrane protein YrbE2A
- Mce-family protein Mce1A
- Possible Mce-family lipoprotein LprK
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0016887 (ATP hydrolysis activity), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity), GO:0017111 (ribonucleoside triphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0071840 (cellular component organization or biogenesis), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0016043 (cellular component organization), GO:0046907 (intracellular transport), GO:0045184 (establishment of protein localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0008104 (protein localization), GO:0043574 (peroxisomal transport), GO:0006996 (organelle organization), GO:0015031 (protein transport), GO:0072594 (establishment of protein localization to organelle), GO:0006625 (protein targeting to peroxisome), GO:0033365 (protein localization to organelle), GO:0072663 (establishment of protein localization to peroxisome), GO:0006605 (protein targeting), GO:0007031 (peroxisome organization), GO:0072662 (protein localization to peroxisome)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)