Protein: Fatty acid 2-hydroxylase (EC 1.-.-.-) (Q8SXY2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}.
Sequence: MPIDMDIPKEAESNDKFIVKYRQQYYDLSRFMHKHPGGINTLKGLNSGDMTARFLKAPPHSDAAMYLMREYKIDPEDSRKPKSSQRETLHHDEDGTLRQRPRETEDKNNNQVDDSMEHLVDWSKAMLPQIANITDCYDEWVHKPVDRPLRLFDPWYLEMCTKTPWWLVPLFWIPVIVKCAVEEFTTAWQDSNQLAVFSGYFLFGVLLWSFLEYTLHRWVFHVKLSNKSGSWLCTFHFMIHGLHHKVPFDPMRLVFPPLPGAVLAAVIYTPLSFVLSHPRVILSGALAGYLCYDMMHYYLHYGNPSLWAFVHMKRYHHHHHFSHQTLGYGISSPLWDVVFKTRIHLRKLRYQLRWS
InterPro domains: - IPR018506: Cytochrome b5, heme-binding site (binding_site) [31-38]
- IPR036400: Cytochrome b5-like heme/steroid binding domain superfamily (homologous_superfamily) [5-88]
- IPR006694: Fatty acid hydroxylase (domain) [201-341]
- IPR014430: Sterol desaturase Scs7 (family) [1-355]
- IPR001199: Cytochrome b5-like heme/steroid binding domain (domain) [6-77]
Interaction partners: - Fatty acid hydroxylase domain-containing protein
- RE26969p)
- Paraplegin, isoform A
- Receptor expression enhancing protein A, isoform I
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006629 (lipid metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006643 (membrane lipid metabolic process), GO:0006672 (ceramide metabolic process), GO:0043604 (amide biosynthetic process), GO:1903509 (liposaccharide metabolic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0046467 (membrane lipid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0006665 (sphingolipid metabolic process), GO:0006677 (glycosylceramide metabolic process), GO:0006664 (glycolipid metabolic process), GO:0046513 (ceramide biosynthetic process), GO:0030148 (sphingolipid biosynthetic process), GO:0009247 (glycolipid biosynthetic process), GO:0006687 (glycosphingolipid metabolic process), GO:0006688 (glycosphingolipid biosynthetic process), GO:0019374 (galactolipid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)