Protein: Ankyrin 2 (A0A0G2KAS9)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Membrane {ECO:0000256|ARBA:ARBA00004370}.
Sequence: MAHAAASIKKVREAELDEKEKNLERERKKQRKIPRDRMERKRKSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLEKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVTEEVTTTTTTITEKHKLNVPETMTEVLDVSDEEGDDTVTGDGGEYLRPEDLKELGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAMIDDTVVIPSHQVSALAKEAERNSYRLSWGTENLDNVALSSSPIHSGFLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCEYTEDELNEILNGMDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNGFGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVAFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRGLVHQAICNLNITLPIYAKESESDQEQEEEICMTSEKNDETESTETSVLKSHLVNEVPVLASPDLLSEVSEMKQDLIKMTAILTTDVSDKAGSIKVKELAKAGEEEPGEPFEIVERVKEDLEKVNAILRSGTYMRDEGSVRSSQSERELEEEWVIVSDEEIEEAKQHAPVEIAEHPCVEVRVDRETKTKVEKDSTGLVNYLTDDLNSYTGTHEKKPQTAPEKSGETSQASAIVKSSESNKGKTSPAEEKQSAQKQVKPSLVIKKPVRRKLKEKQKQKEESPQGSEEKTELKKGSSEESVDEDRGLAPEPLPTAKATSPLIEETPIGSIKDKVKALQKRVEDEQKGRSKLPVRVKGKEDVPKKTTPRTHPVVSPSSKSSPSSKMERHSSLTSSAKTERHSPVSPSSKNEKHSPVSPSAKAERHSPVFSGKPEKHSPGSPSTKNERHSPVSSIKTERHTPVSPSGKTDKRPPVPSSGRTEKHPPVSPGKTEKRSPGAPSIRTPEKQAPGSATGKHEKHLPVSPGKTEKQPPISPTSKTERIEETMSVRELMKAFQSGQDPSKHKTGLFEHKSAKQKQSQDKSKSRVEKEKGHSVTQRETQRIENQTAKRGQRFQVTGAMESRRFRSTTITVGLRTEDPVRERFERTPVIKTPEAVPPVAAAVAAAAAEESHRGAETLQEKTVDEQEDMDLQISPDRKTSTDFSDVIKQELEDNDKYQQFRLTENTEKAQIHLDQVITSPFNTTFPLDYMKDEFLPALSLQSGALGGSSESLKQEVIAGSPCGSLMEGTPQISSEESYKHEGLAETPETSPESLSFSPKKSKEQIGEAKETIKVETPTDIHSEKELPITNDIADSSEKQGAGVPGDSEHVLKEVTQVPPKDVCSKQEDCPGSHSVSLANETCQALTEEGSCRDSQLPLVSSACKTQAVSETQESLATSEVTKAFPPSDATVKTVEGTEPKPQGVIRSPQGLELPLHNRDSEVLSPMADESLAVSHKDSLEASPVLEDNSSHKTPDSLEPSPLKESPCRDSLESSPVEPKMKAGILPSHFPLPAAIAKTDLVAEVASMRSRLLRDPDGSAEDDSLEQTSLMESSGKSPLSPDTPSSEEVSYEVTPKPSDSSTPKPAVIHECAEEDDSENGEKKRFTPEEEMFKMVTKIKTFDELEQEAKQKRDYKREPRQDESSSSSDPDADCSAEVDEQKQMGSTEGESDVPVLVTSESRKASSSSESEPELTQLSKGADSGLLTEPVIRVQPPSPLPSSIDSNSSPEEAQFQPIVPKQYTFKMNEEVKEDPGNPEEDKDCKSHLAEDSQTHSADGADGSHADLNRETPQLEACDGHGCKAVSPSNSATPVSLGVQSPECHDVDKPLAIDNDSLALQDTHGSDLEEREFDPSRVESTQASLPSEHSSLSSSSHCAVPEENESAKEISSPSSPVKVEVTVTDPVLESMSEDCPTQEASTTTHTERFAMDGPVSDIAETDENSHPQITSPYENVASSSFFSGEPSNFQTDTCHPTVVHSPEVYSVIIRSSPEDVIMTSSSSRTDSGEASNCEGHDLDTECEQKSALWPMQSDEPPLSVAPTTPNAPVVTGEQVSKVIITKTDVDADSWSEIREDDAAFEARVKEEEQKIFGLMVDRQSQGTTPDTTPARTPTEEGTPTSEQNPFLFQEGKLFEMTRSGAIDMTKRSYADESLHFFQIGQDSNEETISEDLKEGATGAEPPQTETTSESLELSGPKEAMDDEGELVPDDVSEEIEDLPASDADLDSKVVISASTETPTKEAVSTVAEEPATMQWSDSLSTVKQTSCPTFPEPVGQLDFSTVTRSVYSDRDDESPDSSPEEQKSVIEIPTAPMENVPSAEIKPQIPIRTLPTSVSAPPSAEDESAFSDDFPSGLDGESEEDGAKPKSKIPIKAPPQRTEWHPSHPDISLQKSGVPQGQDVLSRGPDGRSKSESDASSLDAKTKCPVKARSYIETETESRERAEGFESESEEGATKPKLFASRLPVKSRSTSSSSRTGTSPTRESREHFFDLYRNSIEFFEEISDEASKLVDRLTQSEREQEPPSDDESSSALEVSVIENLPPVDTEHSAPEDIFDTRPIWDESIETMIERIPDENGHDRAEDPQDEQERMEERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHATDTVLIECLTKINRMDIVHLLETNTEPLQERMGRTYAEMEQTITLDHSEGFSVLPEELCAVKEKKEQEASKESESSDHPPMVSEEDISVGYSTFQDCIPKTEGDSPAAALSPQMHQESVQQDFSGKMQDQQEYYVTTPGAEVEDTQKATVIPDSLCKTPEDISTPPEEAKPCLQTPVAIEHASPIVQEPEEASEPKEESSPRKTSLVIVESTDDQPQVFEKLDGDAAFQKGDDMPDIPPETVTEEEYVDENGHTVVKKVTRKIIRRYVSSDGTEKEEITMQGMPQEPVNIEDGDSYSKVIKRVVLKSDTQLSEVTLSEPSIVSGTSQFQAEPVEGRRVSKVVKTTMVHGERMEKSLGDSSLATDLPSAKEDFEEDNNE
InterPro domains: - IPR011029: Death-like domain superfamily (homologous_superfamily) [3528-3640]
- IPR036770: Ankyrin repeat-containing domain superfamily (homologous_superfamily) [14-860]
- IPR051165: Multifunctional Ankyrin Repeat Domain-Containing Protein (family) [596-1451]
- IPR002110: Ankyrin repeat (repeat) [45-828]
- IPR040745: Ankyrin, UPA domain (domain) [1306-1435]
- IPR000488: Death domain (domain) [3533-3627]
- IPR000906: ZU5 domain (domain) [981-1286]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0005488 (binding), GO:0005200 (structural constituent of cytoskeleton), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0042221 (response to chemical), GO:0071840 (cellular component organization or biogenesis), GO:0007272 (ensheathment of neurons), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0032989 (cellular component morphogenesis), GO:0044085 (cellular component biogenesis), GO:0008366 (axon ensheathment), GO:0048731 (system development), GO:0016043 (cellular component organization), GO:0010927 (cellular component assembly involved in morphogenesis), GO:0010033 (response to organic substance), GO:0032288 (myelin assembly), GO:0007399 (nervous system development), GO:0042552 (myelination), GO:0051597 (response to methylmercury), GO:0034330 (cell junction organization), GO:0022607 (cellular component assembly), GO:0045216 (cell-cell junction organization), GO:0034329 (cell junction assembly), GO:0007043 (cell-cell junction assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0042995 (cell projection), GO:0043229 (intracellular organelle), GO:0098857 (membrane microdomain), GO:0120025 (plasma membrane bounded cell projection), GO:0005886 (plasma membrane), GO:0043228 (non-membrane-bounded organelle), GO:0043005 (neuron projection), GO:0045121 (membrane raft), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton)