Protein: Ciliary rootlet coiled-coil, rootletin (B1AKD8)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: XREIVTRNLSQPESPVLLPATEMASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERDTEHSQDLESALIRLEEEQQRSASLAQVNAMLREQLDQAGSANQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAYFSNEHSRLLLLWRQVVGFRRLVSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSERTADASNGSLRGLSGQRTPSPPRRSSPGRGRSPRRGPSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLRSALRRGLGLGRAPS
InterPro domains: - IPR055167: Rootletin-like, coiled-coil (domain) [41-192]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0051641 (cellular localization), GO:0022402 (cell cycle process), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0007049 (cell cycle), GO:0071840 (cellular component organization or biogenesis), GO:0007017 (microtubule-based process), GO:0033036 (macromolecule localization), GO:0048522 (positive regulation of cellular process), GO:1903829 (positive regulation of protein localization), GO:0060341 (regulation of cellular localization), GO:0070727 (cellular macromolecule localization), GO:0016043 (cellular component organization), GO:0051130 (positive regulation of cellular component organization), GO:0000226 (microtubule cytoskeleton organization), GO:0031023 (microtubule organizing center organization), GO:0051128 (regulation of cellular component organization), GO:0007098 (centrosome cycle), GO:0044089 (positive regulation of cellular component biogenesis), GO:0044087 (regulation of cellular component biogenesis), GO:0031344 (regulation of cell projection organization), GO:0031346 (positive regulation of cell projection organization), GO:1902117 (positive regulation of organelle assembly), GO:0120034 (positive regulation of plasma membrane bounded cell projection assembly), GO:0033043 (regulation of organelle organization), GO:0032880 (regulation of protein localization), GO:0008104 (protein localization), GO:0006996 (organelle organization), GO:0010638 (positive regulation of organelle organization), GO:1902115 (regulation of organelle assembly), GO:0060491 (regulation of cell projection assembly), GO:0007010 (cytoskeleton organization), GO:0033365 (protein localization to organelle), GO:0120032 (regulation of plasma membrane bounded cell projection assembly), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0045724 (positive regulation of cilium assembly), GO:1902017 (regulation of cilium assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005615 (extracellular space), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0005576 (extracellular region), GO:0005814 (centriole), GO:0043229 (intracellular organelle), GO:0070062 (extracellular exosome), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043230 (extracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0005813 (centrosome), GO:0065010 (extracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:1903561 (extracellular vesicle), GO:0015630 (microtubule cytoskeleton), GO:0015629 (actin cytoskeleton)