Protein: Cholinergic receptor, nicotinic, alpha polypeptide 9 (G3X8Z7)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034104}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00034104}.
Sequence: MNRPHPCISFCWMYFAASGIKAVETANGKYAQKLFSDLFEDYSNALRPVEDTDAVLNVTLQVTLSQIKDMDERNQILTAYLWIRQTWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDGLITWDSPAITKSSCVVDVTYFPFDSQQCNLTFGSWTYNGNQVDIFNALDSGDLSDFIEDVEWEVQGMPAVKNVISYGCCSEPYPDVTFTLLLKRRSSFYIVNLLIPCVLISFLAPLSFYLPAASGEKVSLGVTILLAMTVFQLMVAEIMPASENVPLIGKYYIATMALITASTALTIMVMNIHFCGAEARPVPHWAKVVILKYMSRILFVYDVGESCLSPRHSQEPEQITKVYGKLPGSNLKASRNKDLSRKKELRKLLKNDLGYQGGIPQNTDSYCARYEALTKNIEYIAKCLKDHKATNSKGSEWKKVAKVIDRFFMWIFFAMVFVMTVLIIARAD
InterPro domains: - IPR038050: Neuronal acetylcholine receptor (homologous_superfamily) [241-479]
- IPR006201: Neurotransmitter-gated ion-channel (family) [17-475]
- IPR036734: Neurotransmitter-gated ion-channel ligand-binding domain superfamily (homologous_superfamily) [26-240]
- IPR018000: Neurotransmitter-gated ion-channel, conserved site (conserved_site) [155-169]
- IPR002394: Nicotinic acetylcholine receptor (family) [65-153]
- IPR036719: Neurotransmitter-gated ion-channel transmembrane domain superfamily (homologous_superfamily) [238-477]
- IPR006029: Neurotransmitter-gated ion-channel transmembrane domain (domain) [244-474]
- IPR006202: Neurotransmitter-gated ion-channel ligand-binding domain (domain) [32-236]
Interaction partners: - Acetylcholine receptor subunit delta
- Neuronal acetylcholine receptor subunit alpha-5
- Acetylcholine receptor subunit alpha
- Neuronal acetylcholine receptor subunit alpha-3
- Acetylcholine receptor subunit beta
- Secreted Ly-6/uPAR domain-containing protein 2
- Acetylcholine receptor subunit gamma
- Neuronal acetylcholine receptor subunit beta-4
- Neuronal acetylcholine receptor subunit beta-2
- Neuronal acetylcholine receptor subunit alpha-2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0038023 (signaling receptor activity), GO:0005515 (protein binding), GO:0030594 (neurotransmitter receptor activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0098960 (postsynaptic neurotransmitter receptor activity), GO:0022835 (transmitter-gated channel activity), GO:0015267 (channel activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0005261 (monoatomic cation channel activity), GO:0022824 (transmitter-gated monoatomic ion channel activity), GO:0022839 (monoatomic ion gated channel activity), GO:0022836 (gated channel activity), GO:0099529 (neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential), GO:1904315 (transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential), GO:0099094 (ligand-gated monoatomic cation channel activity), GO:0022834 (ligand-gated channel activity), GO:0015276 (ligand-gated monoatomic ion channel activity), GO:0022848 (acetylcholine-gated monoatomic cation-selective channel activity), GO:0005230 (extracellular ligand-gated monoatomic ion channel activity), GO:0005231 (excitatory extracellular ligand-gated monoatomic ion channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0065008 (regulation of biological quality), GO:0023051 (regulation of signaling), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:1903530 (regulation of secretion by cell), GO:0099177 (regulation of trans-synaptic signaling), GO:0051049 (regulation of transport), GO:0010646 (regulation of cell communication), GO:0042391 (regulation of membrane potential), GO:0051899 (membrane depolarization), GO:0051952 (regulation of amine transport), GO:0051046 (regulation of secretion), GO:0050433 (regulation of catecholamine secretion), GO:0050804 (modulation of chemical synaptic transmission), GO:0014059 (regulation of dopamine secretion), GO:0099171 (presynaptic modulation of chemical synaptic transmission)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0098794 (postsynapse), GO:0043235 (receptor complex), GO:0071944 (cell periphery), GO:0098796 (membrane protein complex), GO:1990351 (transporter complex), GO:0098797 (plasma membrane protein complex), GO:0045211 (postsynaptic membrane), GO:0098590 (plasma membrane region), GO:1902495 (transmembrane transporter complex), GO:0098802 (plasma membrane signaling receptor complex), GO:0045202 (synapse), GO:0005886 (plasma membrane), GO:0099572 (postsynaptic specialization), GO:0097060 (synaptic membrane), GO:0098981 (cholinergic synapse), GO:0099634 (postsynaptic specialization membrane), GO:0034702 (ion channel complex), GO:0005892 (acetylcholine-gated channel complex)