Protein: Putative syntaxin-3 (Q20024)
Organism: Caenorhabditis elegans
Function: Potentially involved in docking of synaptic vesicles at presynaptic active zones (By similarity). Acts in the intestine to regulate anterior body muscle contractions (aBOC) and the expulsion steps during the defecation motor program (DMP).
Subcellular location: Cell membrane {ECO:0000269|PubMed:19028454}; Single-pass type IV membrane protein {ECO:0000305}.
Sequence: MPRDRLKELQEKATVNTIHAYNYDPPARKYDVESQPLINQDADFEMFLERCSNIRGGLKSLEEDYDAVVQLHGALLSTPGADSENSNKLKSHNQMFFSKAEQIKNSLKILSEETSRIPTTACGIMRAKSDQVKSIYKTFENIMLNFNREQDEYKEKAKRKIVDYLKIRNMQLSDEEIENAVSSGNLSEVTKGVMLALNEKKALYDEVKSRADELKNLERQMGELAQMFHDLHIMVVSQAKMVDSIVNSVENATEYAKQARGNVEEARNLQKRARKMKVCIIIGSIIAVLILILFIQSAVCHFTPIC
InterPro domains: - IPR006011: Syntaxin, N-terminal domain (domain) [39-193]
- IPR045242: Syntaxin (family) [86-286]
- IPR000727: Target SNARE coiled-coil homology domain (domain) [199-292]
- IPR006012: Syntaxin/epimorphin, conserved site (conserved_site) [210-249]
- IPR010989: SNARE (homologous_superfamily) [42-259]
Interaction partners: - t-SNARE protein aex-4
- Synaptosomal-associated protein
- PH domain-containing protein
- Soluble NSF attachment protein 29
- Putative syntaxin-5
- Alpha-soluble NSF attachment protein
- Vesicle-trafficking protein SEC22b
- C2 domain-containing protein aex-1
- t-SNARE coiled-coil homology domain-containing protein
- Putative syntaxin 6
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0019953 (sexual reproduction), GO:0001775 (cell activation), GO:2000241 (regulation of reproductive process), GO:2000242 (negative regulation of reproductive process), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0051234 (establishment of localization), GO:0009566 (fertilization), GO:0007343 (egg activation), GO:0140352 (export from cell), GO:0048522 (positive regulation of cellular process), GO:0051302 (regulation of cell division), GO:0051726 (regulation of cell cycle), GO:1903530 (regulation of secretion by cell), GO:0090068 (positive regulation of cell cycle process), GO:0080154 (regulation of fertilization), GO:0051049 (regulation of transport), GO:0006810 (transport), GO:0051781 (positive regulation of cell division), GO:0032940 (secretion by cell), GO:0060627 (regulation of vesicle-mediated transport), GO:0010564 (regulation of cell cycle process), GO:0007338 (single fertilization), GO:0045787 (positive regulation of cell cycle), GO:0006887 (exocytosis), GO:0017157 (regulation of exocytosis), GO:0032465 (regulation of cytokinesis), GO:0046903 (secretion), GO:0051046 (regulation of secretion), GO:0016192 (vesicle-mediated transport), GO:0032467 (positive regulation of cytokinesis), GO:0045055 (regulated exocytosis), GO:0017156 (calcium-ion regulated exocytosis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0032153 (cell division site), GO:0048471 (perinuclear region of cytoplasm), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0098590 (plasma membrane region), GO:0030141 (secretory granule), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0032154 (cleavage furrow), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)