Protein: Adenosine kinase (D6WX36)
Organism: Tribolium castaneum (Red flour beetle)
Function: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives
Subcellular location: Nucleus
Sequence: MQRENLRENMLLGMGNPLLDISATVDKDFLTKYNMKENNAILADESHKNLNSEMIEKYKAEFIAGGSVQNSLRVAQWLLQKPKVTTFFGCVGTDKYSQILKDKAKADGVNVVYQYNDKVPTGTCAVLITGTNRSLCANLAAANCFTIDHIRDPENRKLLESAQYFYISGFFITVSPQSILEVAKHALANDRPFIMNLSAPFISQFYKEPLMQAMPYVDLLFGNETEAETFANEQNFGTKDLKEIALKICNLPKQNENRSRVCVITTGHNPVILAREGKISEFPVDVLSKDKLVDTNGAGDAFAGGFLSQYIQGQSLDVCVRCGIWAASQIVQRSGCTFSGKANFQP
InterPro domains: - IPR011611: Carbohydrate kinase PfkB (domain) [36-339]
- IPR002173: Carbohydrate/purine kinase, PfkB, conserved site (conserved_site) [294-307]
- IPR029056: Ribokinase-like (homologous_superfamily) [11-338]
- IPR001805: Adenosine kinase (family) [6-344]
Interaction partners: - Adenine phosphoribosyltransferase
- Adenylate kinase
- Adenosine deaminase-like protein
- Adenosine deaminase
- Adenosine deaminase
- Purine nucleoside phosphorylase
- purine-nucleoside phosphorylase
- Adenylosuccinate lyase
- GTP:AMP phosphotransferase, mitochondrial
- Adenylate kinase 7-like Protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:0016740 (transferase activity), GO:1901363 (heterocyclic compound binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0097367 (carbohydrate derivative binding), GO:1901265 (nucleoside phosphate binding), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0043168 (anion binding), GO:0000166 (nucleotide binding), GO:0032553 (ribonucleotide binding), GO:0035639 (purine ribonucleoside triphosphate binding), GO:0016301 (kinase activity), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0032555 (purine ribonucleotide binding), GO:0017076 (purine nucleotide binding), GO:0005524 (ATP binding), GO:0019205 (nucleobase-containing compound kinase activity), GO:0019206 (nucleoside kinase activity), GO:0032559 (adenyl ribonucleotide binding), GO:0030554 (adenyl nucleotide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0044249 (cellular biosynthetic process), GO:0043094 (cellular metabolic compound salvage), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0043174 (nucleoside salvage), GO:1901362 (organic cyclic compound biosynthetic process), GO:0043101 (purine-containing compound salvage), GO:0034404 (nucleobase-containing small molecule biosynthetic process), GO:0019438 (aromatic compound biosynthetic process), GO:0018130 (heterocycle biosynthetic process), GO:0009116 (nucleoside metabolic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:1901657 (glycosyl compound metabolic process), GO:0072521 (purine-containing compound metabolic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:1901659 (glycosyl compound biosynthetic process), GO:0072522 (purine-containing compound biosynthetic process), GO:0009163 (nucleoside biosynthetic process), GO:0042278 (purine nucleoside metabolic process), GO:0009119 (ribonucleoside metabolic process), GO:0046128 (purine ribonucleoside metabolic process), GO:0042455 (ribonucleoside biosynthetic process), GO:0042451 (purine nucleoside biosynthetic process), GO:0046085 (adenosine metabolic process), GO:0046129 (purine ribonucleoside biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)