Protein: Protein translocase subunit SecA (EC 7.4.2.8) (Q7WWK0)
Organism: Streptococcus parasanguinis
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|HAMAP-Rule:MF_01382}; Peripheral membrane protein {ECO:0000256|HAMAP-Rule:MF_01382}; Cytoplasmic side {ECO:0000256|HAMAP-Rule:MF_01382}. Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01382}. Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}. Note=Distribution is 50-50. {ECO:0000256|HAMAP-Rule:MF_01382}.
Sequence: MANLLKTIIENDRGEIKRLEKMADKVFSYEEQMAALTDDELKAKTVEFKQRYQDGESLDDLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRTGEGKTLTATMPVYLNALSGKGVHVVTVNEYLTERDATEMGELYSWLGLSVGINLAAKSPAEKKEAYLCDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEARTPLIVSGQTASDTSQLYHMADAYVKTLTEDDYIIDVPSKTIGLSDSGIDKAESYFNLENLYDIENVALTHFIDNALRANYIMILDIDYVVSEDQEILIVDQFTGRTMEGRRYSDGLHQAIEAKEGVPVQEETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIPIPTNRPIARIDHPDLLYPSLKSKFKAVVEDVKSRHEKGQPVLVGTVAVETSDYLSQLLVQAGVPHEVLNAKNHYKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGSERIKAVLDRFKLSEEESVIRSNMFTRQVEGAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAERYDVITANRDLAPEIKAMIKRTIKRIVEGASHSSKEERIEAILNFAKYNLVPEDTISESDIEGKSDKEVIDYLYARAEEIYASQVAKLRDEESVQEFQKVLILRVVDSKWTDHIDALDQLRNAVGLRGYAQNNPVVEYQSESFRMFNDMIGSIEFDVTRLMMKAQIHEQERPRTEHSISTTATRNIAAQQDIPSGIDLSQVKRNDLCPCGSGKKFKNCHGRKF
InterPro domains: - IPR044722: SecA, C-terminal helicase domain (domain) [398-566]
- IPR000185: Protein translocase subunit SecA (family) [3-810]
- IPR014018: SecA motor DEAD (domain) [1-571]
- IPR011116: SecA Wing/Scaffold (domain) [571-780]
- IPR020937: SecA conserved site (conserved_site) [481-496]
- IPR011130: SecA, preprotein cross-linking domain (domain) [227-339]
- IPR011115: SecA DEAD-like, N-terminal (domain) [5-383]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [11-600]
- IPR036266: SecA, Wing/Scaffold superfamily (homologous_superfamily) [573-826]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [87-246]
- IPR004027: SEC-C motif (conserved_site) [818-836]
- IPR036670: SecA, preprotein cross-linking domain superfamily (homologous_superfamily) [229-349]
- IPR001650: Helicase, C-terminal domain-like (domain) [411-570]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0048522 (positive regulation of cellular process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0044403 (biological process involved in symbiotic interaction), GO:0009894 (regulation of catabolic process), GO:0051701 (biological process involved in interaction with host), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0044003 (modulation by symbiont of host process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009891 (positive regulation of biosynthetic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0034248 (regulation of amide metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0034250 (positive regulation of amide metabolic process), GO:0051246 (regulation of protein metabolic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0051247 (positive regulation of protein metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0031331 (positive regulation of cellular catabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0031329 (regulation of cellular catabolic process), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0010468 (regulation of gene expression), GO:0061013 (regulation of mRNA catabolic process), GO:2000112 (regulation of cellular macromolecule biosynthetic process), GO:1902680 (positive regulation of RNA biosynthetic process), GO:0006417 (regulation of translation), GO:2001141 (regulation of RNA biosynthetic process), GO:1903311 (regulation of mRNA metabolic process), GO:0006355 (regulation of DNA-templated transcription), GO:0010608 (post-transcriptional regulation of gene expression), GO:0045893 (positive regulation of DNA-templated transcription), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)