wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: ACD shelterin complex subunit and telomerase recruitment factor (R4GNJ5)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Chromosome, telomere {ECO:0000256|ARBA:ARBA00004574}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MAGSGRLVLRPWIRELILGSETPSSPRAGQLLEDAEAAVAGPSHAPDTSDVGATLLVSDGTHSVRCLVTREALDTSDWEEKEFGFRGTEGRLLLLQDCGVHVQVAEGGAPAEFYLQVDRFSLLPTEQPRLRVPGCNQDLDVQKKLYDCLEEHLSESTSSNAGLSLSQLLDEMREDQEHQGALVCLAESCLTLEGPCTAPPVTHWAASRCKATGEAVYTVPSSMLCISENDQLILSSLGPCQRTQGPELPPPDPALQDLSLTLIASPPSSPSSSGTPALPGHMSSEESGTSISLLPALSLAAPDPGQRSSSQPSPAICSAPATLTPRSPHASRTPSSPLQSCTPSLSPRSHVPSPHQALVTRPQKPSLEFKEFVGLPCKNRPPFPRTGATRGAQEPCSVWYEYEPPCTSLCARVQAVRLPPQLMAWALHFLMDAQPGSEPTPM
InterPro domains: - IPR019437: Shelterin complex subunit TPP1/Est3 (domain) [9-153]
- IPR028631: Adrenocortical dysplasia protein (family) [1-399]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0042162 (telomeric DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0051716 (cellular response to stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0033554 (cellular response to stress), GO:0016043 (cellular component organization), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0006974 (cellular response to DNA damage stimulus), GO:0006259 (DNA metabolic process), GO:0006996 (organelle organization), GO:0000723 (telomere maintenance), GO:0006281 (DNA repair), GO:0051276 (chromosome organization), GO:0032200 (telomere organization), GO:0016233 (telomere capping)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005654 (nucleoplasm), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0016604 (nuclear body), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043231 (intracellular membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Bile salt hydrolase (I3QNT7)
Organism: Bifidobacterium pseudolongum
Function: Not known
Sequence: VDGEDNMFFGRNLDWSFSYGEKVLYTPKDYNYQPVFNGEDRNHAVLGIGIVVDDTPLYFDCANDAGLAVAGLNFPGYAEYASDSVNLTVNVAAYEFPLWVARNFTSVDDVAEALKNVTIVAKPINDQYPVAMLHWIISDATRTIVVEYTASGMHVYDDDI
InterPro domains: - IPR029132: Choloylglycine hydrolase/NAAA C-terminal (domain) [4-159]
- IPR029055: Nucleophile aminohydrolases, N-terminal (homologous_superfamily) [3-159]
- IPR052193: Peptidase C59 family enzymes (family) [5-159]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0016811 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0071704 (organic substance metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0006040 (amino sugar metabolic process), GO:1901071 (glucosamine-containing compound metabolic process), GO:0006044 (N-acetylglucosamine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005618 (cell wall), GO:0009274 (peptidoglycan-based cell wall)
Protein: Inhibitor of apoptosis protein (IAP) (Inhibitor of T-cell apoptosis protein) (Q90660)
Organism: Gallus gallus (Chicken)
Function: Apoptotic suppressor.
Subcellular location: Nucleus. Cytoplasm. Note=Predominantly nuclear. According to PubMed:9372964 it is cytoplasmic.
Sequence: MNIMDSSPLLASVMKQNAHCGELKYDFSCELYRMSTFSTFPVNVPVSERRLARAGFYYTGVQDKVKCFSCGLVLDNWQPGDNAMEKHKQVYPSCSFVQNMLSLNNLGLSTHSAFSPLVASNLSPSLRSMTLSPSFEQVGYFSGSFSSFPRDPVTTRAAEDLSHLRSKLQNPSMSTEEARLRTSHAWPLMCLWPAEVAKAGLDDLGTADKVACVNCGVKLSNWEPKDNAMSEHRRHFPNCPFVENLMRDQPSFNVSNVTMQTHEARVKTFINWPTRIPVQPEQLADAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWIEHAKWFPRCEYLLRVKGGEFVSQVQARFPHLLWNSSCTTSDKPVDENMDPIIHFEPGESPSEDAIMMNTPVVKAALEMGFSRRLIKQTVQSKILATEENYKTVNDLVSELLTAEDEKREEEKERQFEEVASDDLSLIRKNRMALFQRLTSVLPILGSLLSAKVITELEHDVIKQTTQTPSQARELIDTVLVKGNAAASIFRNCLKDFDPVLYKDLFVEKSMKYVPTEDVSGLPMEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKECAPSLRKCPICRGTIKGTVRTFLS
InterPro domains: - IPR041933: BIRC2/BIRC3, UBA domain (domain) [384-430]
- IPR001370: BIR repeat (repeat) [28-331]
- IPR011029: Death-like domain superfamily (homologous_superfamily) [445-572]
- IPR001315: CARD domain (domain) [446-536]
- IPR048875: BIRC2/3-like, UBA domain (domain) [381-433]
- IPR050784: Inhibitor of Apoptosis (family) [28-611]
- IPR001841: Zinc finger, RING-type (domain) [564-599]
Interaction partners: - TNF receptor superfamily member 1A
- TNFRSF1A associated via death domain.
- Uncharacterized protein.
- Mitogen-activated protein kinase kinase kinase 7.
- Caspase 9
- Uncharacterized protein.
- Caspase-3
- TNF receptor-associated factor
- Caspase-7
- E3 ubiquitin-protein ligase XIAP
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0019953 (sexual reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0007276 (gamete generation), GO:0007283 (spermatogenesis), GO:0048232 (male gamete generation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0016020 (membrane), GO:0043226 (organelle), GO:0140513 (nuclear protein-containing complex), GO:0043229 (intracellular organelle), GO:0008180 (COP9 signalosome), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Gamma-sarcoglycan (Gamma-SG) (35 kDa dystrophin-associated glycoprotein) (35DAG) (Q13326)
Organism: Homo sapiens (Human)
Function: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Subcellular location: Cell membrane, sarcolemma {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
Sequence: MVREQYTTATEGICIERPENQYVYKIGIYGWRKRCLYLFVLLLLIILVVNLALTIWILKVMWFSPAGMGHLCVTKDGLRLEGESEFLFPLYAKEIHSRVDSSLLLQSTQNVTVNARNSEGEVTGRLKVGPKMVEVQNQQFQINSNDGKPLFTVDEKEVVVGTDKLRVTGPEGALFEHSVETPLVRADPFQDLRLESPTRSLSMDAPRGVHIQAHAGKIEALSQMDILFHSSDGMLVLDAETVCLPKLVQGTWGPSGSSQSLYEICVCPDGKLYLSVAGVSTTCQEHNHICL
InterPro domains: - IPR006875: Sarcoglycan complex subunit protein (family) [25-278]
- IPR039972: Sarcoglycan gamma/delta/zeta (family) [1-291]
Interaction partners: - Alpha-sarcoglycan
- Dystroglycan 1
- Sarcospan
- Dystrophin
- Delta-sarcoglycan
- Beta-sarcoglycan
- Filamin-C
- Beta-1-syntrophin
- Alpha-1-syntrophin
- Epsilon-sarcoglycan
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0016043 (cellular component organization), GO:0061061 (muscle structure development), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007507 (heart development), GO:0055006 (cardiac cell development), GO:0045229 (external encapsulating structure organization), GO:0042692 (muscle cell differentiation), GO:0035051 (cardiocyte differentiation), GO:0055001 (muscle cell development), GO:0072359 (circulatory system development), GO:0060537 (muscle tissue development), GO:0061024 (membrane organization), GO:0055007 (cardiac muscle cell differentiation), GO:0051146 (striated muscle cell differentiation), GO:0014706 (striated muscle tissue development), GO:0051145 (smooth muscle cell differentiation), GO:0048738 (cardiac muscle tissue development), GO:0035886 (vascular associated smooth muscle cell differentiation), GO:0055013 (cardiac muscle cell development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane), GO:0090665 (glycoprotein complex), GO:0071944 (cell periphery), GO:0098796 (membrane protein complex), GO:0098797 (plasma membrane protein complex), GO:0016010 (dystrophin-associated glycoprotein complex), GO:0005886 (plasma membrane)
Protein: L-lysine 4-chlorinase (EC 1.14.20.-) (Halogenase BesD) (G8XHD5)
Organism: Streptantibioticus cattleyicolor (strain ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057) (Streptomyces cattleya)
Function: Involved in the biosynthesis of terminal alkyne-containing amino acids such as L-propargylglycine (Pra) and L-beta-ethynylserine, that are produced as antibiotics by S.cattleya. Catalyzes the chlorination of L-lysine at the C4 position, leading to the production of 4-chloro-L-lysine.
Sequence: MCAPLEKDDIRRLSQAFHRFGIVTVTELIEPHTRKLVRAEADRLLDQYAERRDLRLATTDYTRRSMSVVPSETIAANSELVTGLYAHRELLAPLEAIAGERLHPCPKADEEFLITRQEQRGDTHGWHWGDFSFALIWVLQAPPIDVGGLLQCVPHTTWDKASPQINRYLVENPIDTYHFESGDVYFLRTDTTLHRTIPLREDTTRIILNMTWAGERDLSRKLAADDRWWDNAEVSAARAIKD
InterPro domains: - IPR056470: L-lysine 4-chlorinase BesD/L-lysine 5-chlorinase HalB-like (family) [6-229]
- IPR053701: L-lysine 4-chlorinase BesD (family) [13-241]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0051213 (dioxygenase activity), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen), GO:0016706 (2-oxoglutarate-dependent dioxygenase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006520 (amino acid metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044283 (small molecule biosynthetic process), GO:0006082 (organic acid metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0008652 (amino acid biosynthetic process), GO:0016053 (organic acid biosynthetic process), GO:0043436 (oxoacid metabolic process), GO:1901605 (alpha-amino acid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process), GO:1901607 (alpha-amino acid biosynthetic process), GO:0009066 (aspartate family amino acid metabolic process), GO:0009067 (aspartate family amino acid biosynthetic process), GO:0006553 (lysine metabolic process), GO:0009085 (lysine biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Leukocyte surface antigen CD53 (Cell surface glycoprotein CD53) (Leukocyte antigen MRC OX-44) (CD antigen CD53) (P24485)
Organism: Rattus norvegicus (Rat)
Function: Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity).
Subcellular location: Cell membrane {ECO:0000250}. Cell junction {ECO:0000250}. Membrane; Multi-pass membrane protein. Note=Concentrates in localized microdomains along the plasma membrane at the contact sites between cells of fused myotubes. {ECO:0000250}.
Sequence: MGMSSLKLLKYVLFFFNFLFWVCGCCILGFGIHLLVQNTYGILFRNLPFLTLGNVLVIVGSIIMVVAFLGCMGSIKENKCLLMSFFVLLLLILLAEVTLAILLFVYEKKINTLVAEGLNDSIQHYHSDNSTRMAWDFIQSQLQCCGVNGSSDWISGPPSSCPSGADVQGCYKKGQAWFHSNFLYIGIVTICVCVIQVLGMSFALTLNCQIDKTSQALGL
InterPro domains: - IPR000301: Tetraspanin, animals (family) [1-218]
- IPR008952: Tetraspanin, EC2 domain superfamily (homologous_superfamily) [104-182]
- IPR018503: Tetraspanin, conserved site (conserved_site) [60-82]
- IPR018499: Tetraspanin/Peripherin (family) [9-209]
Interaction partners: - Lysosomal protein transmembrane 5
- CD48 antigen
- Receptor-type tyrosine-protein phosphatase C
- CD82 antigen
- Integrin beta
- T-cell surface antigen CD2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0051094 (positive regulation of developmental process), GO:0050793 (regulation of developmental process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0060142 (regulation of syncytium formation by plasma membrane fusion), GO:0060143 (positive regulation of syncytium formation by plasma membrane fusion), GO:0051130 (positive regulation of cellular component organization), GO:1901739 (regulation of myoblast fusion), GO:1901741 (positive regulation of myoblast fusion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0005911 (cell-cell junction), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Leucine-rich repeat (LRR) family protein (Q9FHI4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MSTKECDIYKIINILSQLDSDLKKIPVSDKVISHKEQQGEPSEEKRSWWVRVRGSLKRIGKAKKEAFNNASDSGGSQGGSRRSVQNIEEDQKNEDLEIRKLQNDIRQMIAAFKNLTQFQTDMSKNLERDLRSTKLIAILQKKNSFGSRSHVVKEIRRKVSALKCQIPSLLHKQSSRKISITDSQTAEENDEISETGIDIYLPGLHFSEKFKTSSAFEEVVEKFQGLDDFTQKLCLLSFAVFPENREVKRTMLMYWWIGEGFISCDDSENLVTRILDSFSDKKLLEPVEDERKLLPSSYKMEPHVHSAVIYLAKEMDLFELYNKNGKLIMKKSSKKKVCLVKGSSLLRDAKTSVMEPKTLQTVFNSSERYPDFTFKWFPLMDSLRVLYLGRWEQTAKRHIEVESTEFLKNMKSLKNLRLASFQGISRIERLENSICALPELVILDLKACYNLEVLPSDIGLFEKLIYLDVSECYMLDRMPKGIAKLSRLQVLKGFVISESDHENNCAVKHLVNLRKLSITVNKYSFKVESLMESLTGLQGLESLKIAWGACEEPNEAVESRETTNEKKENQGGLATDKKLKDLMEREDDQVQNYGQTSKEEKGNVEETGKQEDGDQGDGINEEANLEDGKKHDEGKEERSLKSDEVVEEEKKTSPSEEATEKFQNKPGDQKGKSNVEGDGDKGKADLEEEKKQDEVEAEKSKSDEIVEGEKKPDDKSKVEKKGDGDKENADLDEGKKRDEVEAKKSESGKVVEGDGKESPPQESIDTIQNMTDDQTKVEKEGDRDKGKVDPEEGKKHDEVEGGIWKSDNGVEGVDKASPSRESTDAIENKPDDHQRGDKQEEKGDGEKEKVNLEEWKKHDEIKEESSKQDNVTGGDVKKSPPKESKDTMESKRDDQKENSKVQEKGDVDKGKAADLDEGKKENDVKAESSKSDKVIEGDEEKNPPQKSKDIIQSKPDDHREISKVQEKVDGEKNGDDLKKLDGGGEAKTQKSRKTTKFGKNVSDHPKRDNTMAEDIHETQSPSRKSKSSKAKWLTGRGNQTKKWGIGWQEDPVVDDTYTLPSNLKKLELECFPETKPPSWLNPKDLKNLKKLSIKGGKLSRIGDESRITEDKWDVEILRLKYLHEFKVEWRDLQTLFPKMTLLEKYKCPKIAFCPTDGNGVWTSSPNM
InterPro domains: - IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [343-559]
- IPR044974: Disease resistance protein, plants (family) [155-566]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [223-309]
- IPR055414: Disease resistance R13L4/SHOC-2-like, LRR domain (domain) [382-553]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0042742 (defense response to bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: At5g63130 (Octicosapeptide/Phox/Bem1p family protein) (Q9FML0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MVAVDYTEKNSGSSLKFLCSYGGRILPRSTDGKLRYVGGHTRVLSVDRSISFSELMKKLYEFCGYSVDLRCQLPNGDLETLISVKSEEELAEIVEEYDRICGAKIRAVLSPPRSSHKTESSPSSSGDRSPKSPFSVTPSPPNSPSPAYGRYLQSRYCLPSTDLPPRRYIQRAEESHCCYACRVHKDSRLVWH
InterPro domains: - IPR053198: Gynoecium Development Regulator (family) [11-143]
- IPR000270: PB1 domain (domain) [29-112]
Interaction partners: - Pyrroline-5-carboxylate reductase
- C2 and GRAM domain-containing protein At5g50170
- Plant intracellular Ras-group-related LRR protein 9
- Gag-Pol-related retrotransposon family protein
- Gag-Pol-related retrotransposon family protein
- Helicase with zinc finger protein
- Uncharacterized mitochondrial protein AtMg00300
- Probable long-chain-alcohol O-fatty-acyltransferase 5
- Uncharacterized mitochondrial protein AtMg00750
- General transcription and DNA repair factor IIH subunit TFB1-3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009620 (response to fungus), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0050832 (defense response to fungus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Mitochondrial carrier protein, putative (Q57ZL4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004448}.
Sequence: MVSEGTSAAGRLEGESPLALRVDTGEIVAGCLAGFVEHFFMFPFDTLKTRVQSGDSTNVILAAKRISRNERLAHLYRGFAPIIVSAVPAHGAYYSTYEAAKRVFGEDSTVSITVSASCAVAAHDTISTPFDVIKQRMQMDGSRKFASSLQCGQCAVAEGGVRCLLLSLPTTILMNIPHFSAYWLVYEGFLAYLGGERRNRETEVAGDYITGGLLAGTVASIVSSPLDVVKTQLQLGLRKNIPDAVRYVLVNRGTKGFFAGVTARVMCTAPAGALSMITYETAKKFMEER
InterPro domains: - IPR018108: Mitochondrial carrier protein, transmembrane region (repeat) [21-287]
- IPR023395: Mitochondrial carrier protein domain superfamily (homologous_superfamily) [25-289]
- IPR002067: Mitochondrial carrier protein (family) [36-138]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0046873 (metal ion transmembrane transporter activity), GO:0046915 (transition metal ion transmembrane transporter activity), GO:0005381 (iron ion transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:0006865 (amino acid transport), GO:0015849 (organic acid transport), GO:0015711 (organic anion transport), GO:0015804 (neutral amino acid transport), GO:0046942 (carboxylic acid transport), GO:0015824 (proline transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0020023 (kinetoplast), GO:0005737 (cytoplasm), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)