Protein: Histocompatibility 13 isoform 1 (A0A0S2Z5V7)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}. Membrane {ECO:0000256|ARBA:ARBA00004366}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004366}; Lumenal side {ECO:0000256|ARBA:ARBA00004366}.
Sequence: MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARGKNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHTISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRKHWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPIKLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYEESNPKDPAAVTESKEGTEASASKGLEKKEK
InterPro domains: - IPR006639: Presenilin/signal peptide peptidase (family) [66-337]
- IPR007369: Peptidase A22B, signal peptide peptidase (family) [32-355]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0008233 (peptidase activity), GO:0046983 (protein dimerization activity), GO:0042802 (identical protein binding), GO:0019899 (enzyme binding), GO:0044389 (ubiquitin-like protein ligase binding), GO:0042803 (protein homodimerization activity), GO:0004175 (endopeptidase activity), GO:0070001 (aspartic-type peptidase activity), GO:0031625 (ubiquitin protein ligase binding), GO:0004190 (aspartic-type endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051641 (cellular localization), GO:0042221 (response to chemical), GO:0006807 (nitrogen compound metabolic process), GO:0051234 (establishment of localization), GO:0051716 (cellular response to stimulus), GO:0065009 (regulation of molecular function), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0033036 (macromolecule localization), GO:0050790 (regulation of catalytic activity), GO:1901564 (organonitrogen compound metabolic process), GO:0046907 (intracellular transport), GO:1901698 (response to nitrogen compound), GO:0033554 (cellular response to stress), GO:0019538 (protein metabolic process), GO:0006810 (transport), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:1901575 (organic substance catabolic process), GO:0043170 (macromolecule metabolic process), GO:0010033 (response to organic substance), GO:0045184 (establishment of protein localization), GO:0034976 (response to endoplasmic reticulum stress), GO:0051341 (regulation of oxidoreductase activity), GO:0009057 (macromolecule catabolic process), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0010243 (response to organonitrogen compound), GO:1901565 (organonitrogen compound catabolic process), GO:0006508 (proteolysis), GO:0015031 (protein transport), GO:0030163 (protein catabolic process), GO:0071702 (organic substance transport), GO:0008104 (protein localization), GO:1903513 (endoplasmic reticulum to cytosol transport), GO:0032527 (protein exit from endoplasmic reticulum), GO:0032768 (regulation of monooxygenase activity), GO:0030970 (retrograde protein transport, ER to cytosol), GO:0033619 (membrane protein proteolysis), GO:0036503 (ERAD pathway), GO:0010498 (proteasomal protein catabolic process), GO:0051603 (proteolysis involved in protein catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0098552 (side of membrane), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0140534 (endoplasmic reticulum protein-containing complex), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:0031984 (organelle subcompartment), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0043229 (intracellular organelle), GO:0098562 (cytoplasmic side of membrane), GO:0098576 (lumenal side of membrane), GO:0098827 (endoplasmic reticulum subcompartment), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005791 (rough endoplasmic reticulum), GO:0098553 (lumenal side of endoplasmic reticulum membrane), GO:0005789 (endoplasmic reticulum membrane), GO:0098554 (cytoplasmic side of endoplasmic reticulum membrane)