Protein: Alpha-(1,4)-fucosyltransferase (EC 2.4.1.-) (FT4-M) (FucTC) (Fucosyltransferase 13) (AtFUT13) (Galactoside 3(4)-L-fucosyltransferase) (Q9C8W3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in cell wall synthesis. Catalyzes alpha-1,4 glycosidic linkages and generates Lewis-a epitopes.
Subcellular location: Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Note=Membrane-bound form in trans cisternae of Golgi. {ECO:0000250}.
Sequence: MPMRYLNAMAALLMMFFTLLILSFTGILEFPSASTSMEHSIDPEPKLSDSTSDPFSDVLVAYKKWDFEVGCARFRENHKDAILGNVSSGSLQEFGCGKLKMKHVKVLVKGWTWIPDNLENLYSCRCGMTCLWTKSSVLADSPDALLFETTTPPLQRRVGDPLRVYMELEAGRKRSGREDIFISYHAKDDVQTTYAGSLFHNNRNYHISPHKNNDVLVYWSSSRCLPHRDRLAKSLLDLIPHHSFGKCLNNVGGLDSALSMYPECVAEHNAEAKWYDHLHCAMSHYKFVLAIENTAVESYVTEKLFYALDSGSVPIYFGASNVQDFVPPHSVIDGSKFGSMQELAAYVKRLGDDPVAYSEYHAWRRCGLMGNYGKTRAVSLDTLPCRLCEEISRRGGKNAGV
InterPro domains: - IPR055270: Fucosyltransferase, C-terminal (domain) [214-394]
- IPR017177: Alpha-(1, 3)-fucosyltransferase/alpha-(1, 4)-fucosyltransferase, plant (family) [1-401]
- IPR001503: Glycosyl transferase family 10 (family) [99-393]
- IPR038577: GT10-like, C-terminal domain superfamily (homologous_superfamily) [164-368]
Interaction partners: - Beta-1,3-galactosyltransferase GALT1
- Beta-hexosaminidase 1
- Alpha-mannosidase 2
- Beta-hexosaminidase 3
- Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
- Beta-1,2-xylosyltransferase
- Beta-hexosaminidase 2
- Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
- Probable alpha-mannosidase At5g66150
- Probable alpha-mannosidase At5g13980
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0008417 (fucosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071554 (cell wall organization or biogenesis), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0044036 (cell wall macromolecule metabolic process), GO:0044085 (cellular component biogenesis), GO:1901576 (organic substance biosynthetic process), GO:0042546 (cell wall biogenesis), GO:0044249 (cellular biosynthetic process), GO:0005975 (carbohydrate metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0044262 (cellular carbohydrate metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:0070589 (cellular component macromolecule biosynthetic process), GO:0044264 (cellular polysaccharide metabolic process), GO:0016051 (carbohydrate biosynthetic process), GO:0005976 (polysaccharide metabolic process), GO:0034637 (cellular carbohydrate biosynthetic process), GO:0010383 (cell wall polysaccharide metabolic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:0044038 (cell wall macromolecule biosynthetic process), GO:0033692 (cellular polysaccharide biosynthetic process), GO:0044042 (glucan metabolic process), GO:0000271 (polysaccharide biosynthetic process), GO:0070592 (cell wall polysaccharide biosynthetic process), GO:0010410 (hemicellulose metabolic process), GO:0006073 (cellular glucan metabolic process), GO:0009250 (glucan biosynthetic process), GO:0010411 (xyloglucan metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0005794 (Golgi apparatus), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0098791 (Golgi apparatus subcompartment), GO:0031985 (Golgi cisterna), GO:0043231 (intracellular membrane-bounded organelle), GO:0005795 (Golgi stack), GO:0031982 (vesicle), GO:0005802 (trans-Golgi network), GO:0000138 (Golgi trans cisterna), GO:0097708 (intracellular vesicle)