Protein: Lysophosphatidic acid receptor 2a (F1QFF1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Cell surface {ECO:0000256|ARBA:ARBA00004241}. Endosome {ECO:0000256|ARBA:ARBA00004177}.
Sequence: MVFNSCEAFDNPVSYFYNRTGKPISPNWRTHDFVVVGLGLPICVFIILANMLVIAAIIVNRKFHFPIYYLLGNMAAADLFAGISYSYLVFHTGPWTINLTIKEWFVRGALINMSLTASVVNLLAVAVERHQTIFTMQLHTTMTRRRVVMLIVTIWVVAVVMGLVPTMGWNCVCDQLGCSTVAPLYSRSFLVFWAILNLMAFFIMVAVYTHIFIYVRRRSQVMSPHTDQPSNNQTVISLMKTMSMILGAFVICWTPGLVILLLDGLKCIECHVLKYEKYCLVLAECNSLVNPIIYSFRDEDMRTTYKRILCFPWRRMRPHEGPSGIRFEPVKTGAPPEKNSQNSSSPEAAPPQSPLS
InterPro domains: - IPR004065: Lysophosphatidic acid receptor (family) [20-315]
- IPR017452: GPCR, rhodopsin-like, 7TM (domain) [49-294]
- IPR000276: G protein-coupled receptor, rhodopsin-like (family) [34-302]
- IPR002277: Lysophosphatidic acid receptor EDG-2 (family) [23-308]
Interaction partners: - Lysophosphatidic acid receptor 1
- G-protein alpha 12 alpha 12) alpha 12a)
- Guanine nucleotide-binding protein
- G-protein alpha 13a, alpha 13a)
- Lysophosphatidic acid receptor 4
- Lysophosphatidic acid receptor 2b
- Transmembrane protein 169a.
- Solute carrier family 10 member 4.
- Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1
- Lysophospholipid acyltransferase 2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004930 (G protein-coupled receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0032501 (multicellular organismal process), GO:0050793 (regulation of developmental process), GO:0002682 (regulation of immune system process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0051239 (regulation of multicellular organismal process), GO:0009653 (anatomical structure morphogenesis), GO:0051093 (negative regulation of developmental process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0048523 (negative regulation of cellular process), GO:0050794 (regulation of cellular process), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0045595 (regulation of cell differentiation), GO:1903706 (regulation of hemopoiesis), GO:2000026 (regulation of multicellular organismal development), GO:0001568 (blood vessel development), GO:0045596 (negative regulation of cell differentiation), GO:0048731 (system development), GO:0035239 (tube morphogenesis), GO:0045637 (regulation of myeloid cell differentiation), GO:0045638 (negative regulation of myeloid cell differentiation), GO:0048514 (blood vessel morphogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0060284 (regulation of cell development), GO:0045646 (regulation of erythrocyte differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0048786 (presynaptic active zone), GO:0098793 (presynapse), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0042734 (presynaptic membrane), GO:0048787 (presynaptic active zone membrane), GO:0045202 (synapse), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0097060 (synaptic membrane), GO:0098978 (glutamatergic synapse)