Protein: Integrin subunit alpha 5 (A0A8I6A7G7)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
Sequence: MGSWTPRSPRSPLHAVLLRWGPRRLPPLLPLLLLLWPPPLQVGGFNLDAEAPAVLSGPPGSLFGFSVEFYRPGRDGVSVLVGAPKANTSQPGVLQGGAVYVCPWGTSPIQCSTIQFDSKGSRILESSLYSEEPVEYKSLQWFGATVRAHGSSILACAPLYSWRTEKDPQNDPVGTCYLSTENFTRILEYAPCRSDFGSAAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQISESYYPQYLINPVQGQLQTRQASSVYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVTVLNGSDIHSLYNVSGEQMASYFGYAVAATDTNGDGLDDLLVGAPLLMERTADGRPQEVGRVYIYLQHPEGIEPTPSLTLTGQDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGEAQQGVVFIFPGGPGGLNTKPSQVLQPLWAAGHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKALVYRGRPIISASASLTIFPSMFNPEERSCSLEGNPVSCINLSFCLNASGKHVPNSIGFEVELQLDWQKQKGGVRRALFLASKQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHIALNFSLDPKAPMDSHGLRPVLHYQSKSRIEDKAQILLDCGEDNICVPDLQLAVYGEKKHVYLGDKNALNLTFLAQNLGEGGAYEAELRVTAPLEAEYSGLVRHPGNFSSLSCDYFAVNQSRQLVCDLGNPMKAGTSIWGGLRFTVPHLQDTKKTIQFDFQILSKNLNNSQSNMVSFPLSVEAQAQVSLNGVSKPEAVIFPVSDWNPQDQPQKEGDLGPAVHHVYELINQGPSSISQGVLEISCPQALEGQQLLYVTKVTGLNNCTSNYTPNSQGLELDPEVSPHHLQRREAPGRSSTTSGTQVLKCPEAKCFRLRCEFGPLHRQESRSLQLHFRVWAKTFLQEYQPFSLQCEALYEALKMPYQILPRQLPQKKLQVATAVQWTKAEGSNGVPLWIIILAILFGLLLLGLLIYVLYKLGFFKPNPPLSSNPPNLFKLCC
InterPro domains: - IPR048285: Integrin alpha, second immunoglobulin-like domain (domain) [645-786]
- IPR000413: Integrin alpha chain (family) [269-1028]
- IPR013649: Integrin alpha, first immunoglubulin-like domain (domain) [490-644]
- IPR028994: Integrin alpha, N-terminal (homologous_superfamily) [45-492]
- IPR013517: FG-GAP repeat (repeat) [326-428]
- IPR032695: Integrin domain superfamily (homologous_superfamily) [491-1002]
- IPR013519: Integrin alpha beta-propellor (repeat) [46-508]
- IPR048286: Integrin alpha, third immunoglobulin-like domain (domain) [792-988]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0060089 (molecular transducer activity), GO:0044877 (protein-containing complex binding), GO:0038023 (signaling receptor activity), GO:0005515 (protein binding), GO:0050839 (cell adhesion molecule binding), GO:0005178 (integrin binding), GO:0005102 (signaling receptor binding), GO:0070851 (growth factor receptor binding), GO:0005154 (epidermal growth factor receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0051716 (cellular response to stimulus), GO:0044706 (multi-multicellular organism process), GO:0044703 (multi-organism reproductive process), GO:0007155 (cell adhesion), GO:0007154 (cell communication), GO:0040017 (positive regulation of locomotion), GO:0007165 (signal transduction), GO:0040012 (regulation of locomotion), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0030155 (regulation of cell adhesion), GO:0007166 (cell surface receptor signaling pathway), GO:0045785 (positive regulation of cell adhesion), GO:0007565 (female pregnancy), GO:2000145 (regulation of cell motility), GO:2000147 (positive regulation of cell motility), GO:0010811 (positive regulation of cell-substrate adhesion), GO:0030335 (positive regulation of cell migration), GO:0007229 (integrin-mediated signaling pathway), GO:0030334 (regulation of cell migration), GO:0010810 (regulation of cell-substrate adhesion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0098794 (postsynapse), GO:0005615 (extracellular space), GO:0098636 (protein complex involved in cell adhesion), GO:0043235 (receptor complex), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0098796 (membrane protein complex), GO:0005576 (extracellular region), GO:0045211 (postsynaptic membrane), GO:0098797 (plasma membrane protein complex), GO:0098590 (plasma membrane region), GO:0098802 (plasma membrane signaling receptor complex), GO:0045202 (synapse), GO:0008305 (integrin complex), GO:0005886 (plasma membrane), GO:0097060 (synaptic membrane), GO:0098978 (glutamatergic synapse)