wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Anaerobic sulfatase-maturating enzyme homolog YdeM (AnSME homolog) (P76134)
Organism: Escherichia coli (strain K12)
Function: Not known
Sequence: MHVTAKPSSFQCNLKCDYCFYLEKESQFTHEKWMDDSTLKEFIKQYIAASGNQVYFTWQGGEPTLAGLDFFRKVIHYQQRYAGQKRIFNALQTNGILLNNEWCAFLKEHEFLVGISIDGPQELHDRYRRSNSGNGTFAKVIAAIERLKSYQVEFNTLTVINNVNVHYPLEVYHFLKSIGSKHMQFIELLETGTPNIDFSGHSENTFRIIDFSVPPTAYGKFMSTIFMQWVKNDVGEIFIRQFESFVSRFLGNGHTSCIFQESCKDNLVVESNGDIYECDHFVYPQYKIGNINKSELKTMNSVQLTAQKKRIPAKCQQCAYKPICNGGCPKHRITKVNNETVSYFCEGYKILFSTMVPYMNAMVELAKNRVPLYHIMDVAKQMENN
InterPro domains: - IPR007197: Radical SAM (domain) [1-231]
- IPR023885: 4Fe4S-binding SPASM domain (domain) [264-345]
- IPR023867: Anaerobic sulphatase maturase, radical SAM (family) [2-379]
- IPR047207: Anaerobic sulfatase maturating enzyme, SPASM domain (domain) [256-357]
- IPR013785: Aldolase-type TIM barrel (homologous_superfamily) [1-367]
- IPR034491: Anaerobic Ser-type sulfatase-maturating enzyme (family) [1-381]
Interaction partners: - Uncharacterized sulfatase YdeN
- Uncharacterized protein YidF
- UPF0718 protein YraQ
- Uncharacterized sulfatase YidJ
- Putative sulfatase AslA
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016782 (transferase activity, transferring sulphur-containing groups), GO:0016783 (sulfurtransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0090304 (nucleic acid metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0010467 (gene expression), GO:0018130 (heterocycle biosynthetic process), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0016070 (RNA metabolic process), GO:0032774 (RNA biosynthetic process), GO:0097659 (nucleic acid-templated transcription), GO:0006351 (DNA-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Na(+)-translocating NADH-quinone reductase subunit D (Na(+)-NQR subunit D) (Na(+)-translocating NQR subunit D) (EC 7.2.1.1) (NQR complex subunit D) (NQR-1 subunit D) (Q57095)
Organism: Vibrio alginolyticus
Function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_00428, ECO:0000305}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00428}.
Sequence: MSSAQNVKKSILAPVLDNNPIALQVLGVCSALAVTTKLETAFVMTLAVTFVTALSNFSVSLIRNHIPNSVRIIVQMAIIASLVIVVDQVLKAYLYDISKQLSVFVGLIITNCIVMGRAEAFAMKSAPVPSLIDGIGNGLGYGFVLITVGFFRELFGSGKLFGLEVLPLVSNGGWYQPNGLMLLAPSAFFLIGFLIWVIRILKPEQVEAKE
InterPro domains: - IPR011292: Na(+)-translocating NADH-quinone reductase subunit D (family) [2-207]
- IPR003667: NqrDE/RnfAE (family) [3-210]
Interaction partners: - Na
- Na
- Na
- Na
- Na
- NADH:ubiquinone reductase
- FAD:protein FMN transferase
- Electron transport complex subunit RsxD
- Electron transport complex subunit RsxG
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016651 (oxidoreductase activity, acting on NAD(P)H), GO:0016655 (oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0006811 (monoatomic ion transport), GO:0006812 (monoatomic cation transport), GO:0030001 (metal ion transport), GO:0000041 (transition metal ion transport), GO:0006826 (iron ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Cerebellar degeneration-related antigen 1 (CDR34) (P51861)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MAWLEDVDFLEDVPLLEDIPLLEDVPLLEDVPLLEDTSRLEDINLMEDMALLEDVDLLEDTDFLEDLDFSEAMDLREDKDFLEDMDSLEDMALLEDVDLLEDTDFLEDPDFLEAIDLREDKDFLEDMDSLEDLEAIGRCGFSGRHGFFGRRRFSGRPKLSGRLGLLGRRGFSGRLGGYWKTWIFWKTWIFWKTWIFRKTYIGWKTWIFSGRCGLTGRPGFGGRRRFFWKTLTDWKTWISFWKTLIDWKTWISFWKTLIDWKI
InterPro domains: - IPR048507: WKTW repeat (repeat) [179-199]
- IPR048506: LED repeat (repeat) [1-176]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0050794 (regulation of cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0019222 (regulation of metabolic process), GO:0044238 (primary metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0006629 (lipid metabolic process), GO:0019637 (organophosphate metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0006644 (phospholipid metabolic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Glutinol synthase (KdGLS) (EC 5.4.99.49) (E2IUA7)
Organism: Kalanchoe daigremontiana (Devil's backbone) (Bryophyllum daigremontianum)
Function: Oxidosqualene cyclase that generates glutinol, a triterpenoid product. Glutinol is probably required to coat the leaf exterior as a defense compound against pathogens or herbivores.
Sequence: MWKLKIADGGSNPYIFTTNNFVGRQIWEFDPQATDPQQLAKVEAARLDFYHNRYKLKPNSDLLWRMQFLEEKDFRQNIPQVKVEDGEEVSYEAVTAALRRGVHLYSALQASDGHWPAENAGPMFFMPPMVMCLYITGHLNAIFTEEHRSETLRYIYYHQNEDGGWGFHIEGHSTMFGTVLNYICMRLLGEGPEGGQDNAVSRGRKWILDHGGATSIPSWGKTWLSIMGLCDWSGCNPMPPEFWLLPSYLPMHPGKMWCYCRMVYMPMSYLYGKRFTARITPLILQLREEIHIQPYDQIDWKKVRHVCCKEDMYYPHPLLQDLLWDTLYLTTEPLLTRWPLNKLIRQRALQKTMKHIHYEDENSRYITIGTVEKVLCMLACWVEDPNGDYFKKHLARVPDYFWVAEDGMKIQSFGSQHWDTVFSAQALLASDMADEIGTTLAKAHYCIKESQVKDNPSGDFRSMYRHISKGSWTFSDQDHGWQLSDCTAEGLKCCLLFSLMQPEVVGEAMPPERLFDSVNILLYLQSKNGGMPGWEPAGASEWLELLNPTEFFENIVIEHEYVECTSSAVQALVLFKKLHPGHRRKEVERFITNGAKYIEDIQMPDGAWYGNWGVCFTYGAWFALGGLAAAGKTYNNCAAVRKGVDFLLRIQLEDGGWGESYQSCPDKKYVPLEDNRSNLVHTSWALMGLLCSGQADRDPNPLHRAAKLLINSQLEDGDFPQQEITGVFKMNCMLHFAAYRSIFPVWALAEYKRFCNLSSEAISKPSK
InterPro domains: - IPR008930: Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid (homologous_superfamily) [121-753]
- IPR032696: Squalene cyclase, C-terminal (domain) [417-753]
- IPR032697: Squalene cyclase, N-terminal (domain) [105-362]
- IPR018333: Squalene cyclase (family) [1-753]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016853 (isomerase activity), GO:0016866 (intramolecular transferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0006720 (isoprenoid metabolic process), GO:0008299 (isoprenoid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0006721 (terpenoid metabolic process), GO:0016114 (terpenoid biosynthetic process), GO:0006722 (triterpenoid metabolic process), GO:0016104 (triterpenoid biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)
Protein: Asparaginyl endopeptidase Rep2 (EC 3.4.22.-) (Vacuolar-processing enzyme 3) (OsVPE3) (Q8GS39)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Asparaginyl endopeptidase that may act as an activator of REP1.
Sequence: MAARWCFALLLALSAAAAGAGAKRTWEPVIRMPGEVVEEEVATVPRGSEGTEEEEKDGVGTRWAVLVAGSSGYGNYRHQADVCHAYQILRKGGLKEENIVVFMYDDIANNILNPRPGVIVNHPQGEDVYAGVPKDYTGDEVTAKNFYAVLLGNKTAVTGGSRKVIDSKPNDHIFIFYSDHGGPGVLGMPNLPYLYAADFMKVLQEKHASNTYAKMVIYVEACESGSIFEGLMPEDLNIYVTTASNAEESSWGTYCPGMEPSPPSEYITCLGDLYSVSWMEDSETHNLKEESIKKQYEVVKKRTSDMNSYGAGSHVMEYGDRTFKDDKLYLYQGFDPANAEVKNKLSWEGPKAAVNQRDADLLFLWRRYELLHDKSEEKLKALREISDTVMHRKLLDSSVDLVGKLLFGFGNGPSVLQAVRPSGQPLVDDWDCLKRMVRIFESHCGPLTQYGMKHMRAFANICNNGISGASMKEASIATCSSHNSGRWSSLVQGYSA
InterPro domains: - IPR001096: Peptidase C13, legumain (family) [3-496]
- IPR046427: Legumain prodomain superfamily (homologous_superfamily) [356-487]
- IPR043577: Asparaginyl endopeptidase (family) [1-496]
- IPR048501: Legumain, prodomain (domain) [358-479]
Interaction partners: - Os02g0219400 protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008234 (cysteine-type peptidase activity), GO:0004175 (endopeptidase activity), GO:0004197 (cysteine-type endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0016043 (cellular component organization), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0051604 (protein maturation), GO:0006508 (proteolysis), GO:0006996 (organelle organization), GO:0010467 (gene expression), GO:0007033 (vacuole organization), GO:0016485 (protein processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0005773 (vacuole), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000325 (plant-type vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0000322 (storage vacuole), GO:0000326 (protein storage vacuole)
Protein: At1g58270/F19C14_8 (F19C14.11 protein) (TRAF-like family protein) (ZW9 protein) (Q9SLV3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MYSEEKKSRNYGSIFVYCFFCFVLIVEVARFAKPYINLQNLIETEAVVEEGFMAVGNSGNLPCGSSKPSSASVRAHDEQKLSQAVTTDTRTRPPNSYCVKFQSFVTMAKQVKENGGKYESRPFSVGGYNWTLLIYPVIYIPTDSGGYVSIYVRVDNSSLITNPKDVYAEITFLAYKSSTDKYQISQETEAQRFHLFKQQWGLLQFLPIYYFENPAYGYFFEGESVVFGVDINIVKPFENWEVFSNEQNIRDPIFEWRLTKFSTRFLDSYTSDSFSSGGRNWALKVYPNGVGNATGNSLSLYLLSDQSNDKGYVEAKLRVIDQIQSNNFEKKVAAWPNATENGWGFDRFLSFADIKNTSKGFLVNDTLKLEVQILSFSKTDYYSHQSSLNVLTGDST
InterPro domains: - IPR002083: MATH/TRAF domain (domain) [94-373]
- IPR008974: TRAF-like (homologous_superfamily) [78-375]
Interaction partners: - TCP-1/cpn60 chaperonin family protein
- Jacalin-related lectin 32
- ATP synthase subunit O, mitochondrial
- Myrosinase 5
- Universal stress protein PHOS32
- ATP synthase subunit beta-1, mitochondrial
- Probable mitochondrial-processing peptidase subunit beta, mitochondrial
- Dirigent protein 6
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0046907 (intracellular transport), GO:0045184 (establishment of protein localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0008104 (protein localization), GO:0015031 (protein transport), GO:0072594 (establishment of protein localization to organelle), GO:0033365 (protein localization to organelle), GO:0006623 (protein targeting to vacuole), GO:0072666 (establishment of protein localization to vacuole), GO:0006605 (protein targeting), GO:0072665 (protein localization to vacuole)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031967 (organelle envelope), GO:0005773 (vacuole), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009526 (plastid envelope), GO:0000325 (plant-type vacuole), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle), GO:0009941 (chloroplast envelope)
Protein: Mannose-1-phosphate guanyltransferase (EC 2.7.7.13) (Q7D5T3)
Organism: Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Function: Not known
Sequence: MATHQVDAVVLVGGKGTRLRPLTLSAPKPMLPTAGLPFLTHLLSRIAAAGIEHVILGTSYKPAVFEAEFGDGSALGLQIEYVTEEHPLGTGGGIANVAGKLRNDTAMVFNGDVLSGADLAQLLDFHRSNRADVTLQLVRVGDPRAFGCVPTDEEDRVVAFLEKTEDPPTDQINAGCYVFERNVIDRIPQGREVSVEREVFPALLADGDCKIYGYVDASYWRDMGTPEDFVRGSADLVRGIAPSPALRGHRGEQLVHDGAAVSPGALLIGGTVVGRGAEIGPGTRLDGAVIFDGVRVEAGCVIERSIIGFGARIGPRALIRDGVIGDGADIGARCELLSGARVWPGVFLPDGGIRYSSDV
InterPro domains: - IPR029044: Nucleotide-diphospho-sugar transferases (homologous_superfamily) [2-308]
- IPR005835: Nucleotidyl transferase domain (domain) [8-235]
- IPR050486: Mannose-1-phosphate guanyltransferase (family) [8-344]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016779 (nucleotidyltransferase activity), GO:0070568 (guanylyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0071554 (cell wall organization or biogenesis), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0044036 (cell wall macromolecule metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044085 (cellular component biogenesis), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0042546 (cell wall biogenesis), GO:0006082 (organic acid metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:0006631 (fatty acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0016053 (organic acid biosynthetic process), GO:0070589 (cellular component macromolecule biosynthetic process), GO:0009273 (peptidoglycan-based cell wall biogenesis), GO:0034645 (cellular macromolecule biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0044038 (cell wall macromolecule biosynthetic process), GO:0006633 (fatty acid biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0071766 (Actinobacterium-type cell wall biogenesis), GO:0046394 (carboxylic acid biosynthetic process), GO:0072330 (monocarboxylic acid biosynthetic process), GO:0032787 (monocarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030312 (external encapsulating structure), GO:0005618 (cell wall), GO:0005886 (plasma membrane), GO:0009274 (peptidoglycan-based cell wall)
Protein: Probable aquaporin PIP2-5 (Plasma membrane intrinsic protein 2-5) (AtPIP2;5) (Plasma membrane intrinsic protein 2d) (PIP2d) (Q9SV31)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Sequence: MTKEVVGDKRSFSGKDYQDPPPEPLFDATELGKWSFYRALIAEFIATLLFLYVTIMTVIGYKSQTDPALNPDQCTGVGVLGIAWAFGGMIFILVYCTAGISGGHINPAVTFGLLLARKVTLVRAVMYMVAQCLGAICGVALVKAFQSAYFTRYGGGANGLSDGYSIGTGVAAEIIGTFVLVYTVFSATDPKRSARDSHVPVLAPLPIGFAVFIVHLATIPITGTGINPARSLGAAIIYNKDKAWDHHWIFWVGPFAGAAIAAFYHQFVLRAGAIKALGSFRSQPHV
InterPro domains: - IPR000425: Major intrinsic protein (family) [31-268]
- IPR034294: Aquaporin transporter (family) [11-279]
- IPR022357: Major intrinsic protein, conserved site (conserved_site) [104-112]
- IPR023271: Aquaporin-like (homologous_superfamily) [23-286]
Interaction partners: - Probable aquaporin PIP2-8
- Syntaxin-121
- PAMP-induced secreted peptide 1
- Probable aquaporin SIP1-2
- Probable aquaporin SIP2-1
- Aquaporin SIP1-1
- Aquaporin PIP2-7
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015267 (channel activity), GO:0005372 (water transmembrane transporter activity), GO:0003723 (RNA binding), GO:0015250 (water channel activity), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0051234 (establishment of localization), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0001101 (response to acid chemical), GO:1901700 (response to oxygen-containing compound), GO:0009414 (response to water deprivation), GO:0010035 (response to inorganic substance), GO:0009415 (response to water), GO:0010033 (response to organic substance), GO:0006810 (transport), GO:1902074 (response to salt), GO:0071702 (organic substance transport), GO:0042044 (fluid transport), GO:0006833 (water transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Protein 4.1 (Band 4.1) (Erythrocyte membrane protein band 4.1) (A0A3B3IUD6)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Cytoplasm, cell cortex {ECO:0000256|ARBA:ARBA00004544}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MTTEKSLVTEAENSQHQQKEEGEEAINSGQQEPQQEESCQTAAEGDNWCEQKLKASNGDTPTHEDLTKNKERTSESRGLSRLFSSFLKRPKSQVSEEEGKEVESDKEKGEGGQKEIEFGTSLDEEIILKAPIAAPEPELKTDPSLDLHSLSSAETQTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGVDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEQYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRASRSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPKAQKETVKAEVKKEDEPPEQAEPEPTEAWKVEKTHIEVTVPTSNGDQTQKLAEKTEDLIRMRKDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPFRTLNINGQIPTGEGVSTLST
InterPro domains: - IPR035963: FERM superfamily, second domain (homologous_superfamily) [185-290]
- IPR019747: FERM conserved site (conserved_site) [158-294]
- IPR029071: Ubiquitin-like domain superfamily (homologous_superfamily) [150-184]
- IPR000798: Ezrin/radixin/moesin-like (family) [167-318]
- IPR000299: FERM domain (domain) [100-385]
- IPR019749: Band 4.1 domain (domain) [104-295]
- IPR014352: FERM/acyl-CoA-binding protein superfamily (homologous_superfamily) [182-289]
- IPR007477: SAB domain (domain) [540-588]
- IPR018980: FERM, C-terminal PH-like domain (domain) [299-389]
- IPR014847: FERM adjacent (domain) [392-438]
- IPR019748: FERM central domain (domain) [186-295]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [290-384]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0043933 (protein-containing complex organization), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)