Protein: DNA-binding transcriptional regulator NtrC (Nitrogen regulation protein NR(I)) (Nitrogen regulator I) (Q74EF9)
Organism: Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Sequence: MLLNRILVADDEESMRWVLSKALRKKGFTVDLARDGEEALRLIQSNEYDLAILDIKMPGFTGLELLDKVRELKHDLLMVIMTAEASMKNAVEAMKRGAYDYITKPFDLDVIDAIIEKVHKAREITSQMTILREELKERYHLEKNIIGNSPAMREVYKTIGKVAPSDVTVLVQGESGTGKELIARAIHFNSKRIGKPFIALNCAAIPKDLLESELFGFEKGAFTGAVERKLGKFEQANGGTIFLDEIGDMPLDLQAKILRVLQEKEVTRTGGSQNIAVDVRIVAATNQNLEELVRKKQFREDLFYRLNVVPIQLVPLRERKEDVPLLVDYFLQNACAELEVSPKKCSPEAMALLTTHSWPGNVRELENTIKRAVILSSDPLLTPSDFPGLRARQTGSEATAADDLSLEALVDMKLRASLTNLDKMESGDIYNLVLKQIERPLIRFVLEKTRGNQVKGAEILGINRNTLRKKIQELGIELRKD
InterPro domains: - IPR003593: AAA+ ATPase domain (domain) [165-319]
- IPR025944: Sigma-54 interaction domain, conserved site (conserved_site) [358-367]
- IPR001789: Signal transduction response regulator, receiver domain (domain) [4-119]
- IPR025943: Sigma-54 interaction domain, ATP-binding site 2 (binding_site) [231-246]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [358-476]
- IPR002078: RNA polymerase sigma factor 54 interaction domain (domain) [145-374]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [137-387]
- IPR011006: CheY-like superfamily (homologous_superfamily) [5-189]
- IPR002197: DNA binding HTH domain, Fis-type (domain) [434-477]
- IPR058031: NorR-like, AAA+ ATPase lid domain (domain) [317-398]
- IPR025662: Sigma-54 interaction domain, ATP-binding site 1 (binding_site) [169-182]
Interaction partners: - histidine kinase
- histidine kinase
- DNA-binding transcriptional regulator NtrC)
- RNA polymerase sigma-54 factor RpoN
- Amidohydrolase, YcaC-related protein
- Glutamate dehydrogenase
- histidine kinase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048522 (positive regulation of cellular process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009891 (positive regulation of biosynthetic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0010468 (regulation of gene expression), GO:1902680 (positive regulation of RNA biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0045893 (positive regulation of DNA-templated transcription), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0032993 (protein-DNA complex)