Protein: Phosphopantothenoylcysteine synthetase, isoform C (EC 6.3.2.5) (E2QD26)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MTHWEDFYNTHLPPADFEDNRSLLKEFCERHNKLQNRIVLVTSGGTTVPLEHNTVRFVDNFSAGTRGSASAEYFLDHDYAVIFMHRHKSLEPFTRHFTGQQFFDMLDIADNSQSSTIAIKPDSVDVFAPVLAKYKIARETQMILYVNFTSVVDYMWLLRAACECLAAFEERAVLYLAAAVSDFYIPEDMMPTHKMQSGDGAPTISLQLVPKMLAPLASLWVPHAFVVSFKLETDESLLIVKARDSLNKYKHKLVIANVLQTRKHRVVFVTPTDSYELHLTREQTLQGLEIEEPIVADVVQKHGEFISNAQQRQXPLSMRRRPQTQHQQHHHQQLATGDEDEDGGDLDRDPYCVTSSHYCRVLNPGTPGFARKY
InterPro domains: - IPR035929: CoaB-like superfamily (homologous_superfamily) [20-310]
- IPR007085: DNA/pantothenate metabolism flavoprotein, C-terminal (domain) [34-263]
Interaction partners: - pantothenate kinase
- Phosphopantothenoylcysteine decarboxylase
- 4'-phosphopantetheine phosphatase
- Bifunctional coenzyme A synthase
- FI04487p
- cystathionine gamma-lyase
- Aspartate aminotransferase, cytoplasmic
- Aspartate aminotransferase
- Cysteine dioxygenase
- Deoxyuridine 5'-triphosphate nucleotidohydrolase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016874 (ligase activity), GO:0016879 (ligase activity, forming carbon-nitrogen bonds), GO:0016881 (acid-amino acid ligase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0042592 (homeostatic process), GO:0022414 (reproductive process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0051641 (cellular localization), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0007300 (ovarian nurse cell to oocyte transport), GO:0090130 (tissue migration), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0009791 (post-embryonic development), GO:0048878 (chemical homeostasis), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0030029 (actin filament-based process), GO:0048609 (multicellular organismal reproductive process), GO:0032989 (cellular component morphogenesis), GO:0007276 (gamete generation), GO:0048736 (appendage development), GO:0007281 (germ cell development), GO:0002165 (instar larval or pupal development), GO:0007552 (metamorphosis), GO:0030707 (follicle cell of egg chamber development), GO:0055088 (lipid homeostasis), GO:0048729 (tissue morphogenesis), GO:0044085 (cellular component biogenesis), GO:0007303 (cytoplasmic transport, nurse cell to oocyte), GO:0007293 (germarium-derived egg chamber formation), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048513 (animal organ development), GO:0090132 (epithelium migration), GO:0048138 (germ-line cyst encapsulation), GO:0051649 (establishment of localization in cell), GO:0035107 (appendage morphogenesis), GO:0030036 (actin cytoskeleton organization), GO:0000902 (cell morphogenesis), GO:0009887 (animal organ morphogenesis), GO:0046907 (intracellular transport), GO:0009888 (tissue development), GO:0046843 (dorsal appendage formation), GO:0006810 (transport), GO:0016043 (cellular component organization), GO:0009886 (post-embryonic animal morphogenesis), GO:0007306 (egg chorion assembly), GO:0010927 (cellular component assembly involved in morphogenesis), GO:0007297 (follicle cell of egg chamber migration), GO:0016477 (cell migration), GO:0010631 (epithelial cell migration), GO:0035120 (post-embryonic appendage morphogenesis), GO:0007423 (sensory organ development), GO:0048707 (instar larval or pupal morphogenesis), GO:0048477 (oogenesis), GO:0035114 (imaginal disc-derived appendage morphogenesis), GO:0048139 (female germ-line cyst encapsulation), GO:0002009 (morphogenesis of an epithelium), GO:0045229 (external encapsulating structure organization), GO:0001667 (ameboidal-type cell migration), GO:0030708 (germarium-derived female germ-line cyst encapsulation), GO:0030855 (epithelial cell differentiation), GO:0022607 (cellular component assembly), GO:0055091 (phospholipid homeostasis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0007292 (female gamete generation), GO:0048737 (imaginal disc-derived appendage development), GO:0002064 (epithelial cell development), GO:0055090 (acylglycerol homeostasis), GO:0048569 (post-embryonic animal organ development), GO:0016482 (cytosolic transport), GO:0048563 (post-embryonic animal organ morphogenesis), GO:0007560 (imaginal disc morphogenesis), GO:0007444 (imaginal disc development), GO:0060429 (epithelium development), GO:0006996 (organelle organization), GO:0007472 (wing disc morphogenesis), GO:0007010 (cytoskeleton organization), GO:0035220 (wing disc development), GO:0022416 (chaeta development), GO:0007476 (imaginal disc-derived wing morphogenesis), GO:0070328 (triglyceride homeostasis), GO:0016333 (morphogenesis of follicular epithelium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)