wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Uncharacterized protein (B6K6Z7)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Sequence: MNSSVLHSEGAATANGKSAAMSSSSVARGNLIPTNTTSGRVRLQKKASMAAKSGSRWMDHERENLQAYDYLCRIGEAKQWLEECLQEDLGVTTDFEKSLRNGIVLAQLAQHFAPEFVPRIFTAKKLQFRHSDNINCFLRFAKALGLPENYSFELTDLYEGKNIPKVIYCIHALSFLLFNEGKAPSLHNLEGQLSFTDEEVTAMQRYLDQTGTALPNFTALSNELVTKKHLNSNPPSPYKSPVHVHAHTRSIDVSSGRSRASSLVSSSDEMLLTPLTSPRSSPHRRSRSEFPPPSFTSPSRSSSNSLHSLAKTISFEDPYFQSHRVGNRSERSSPVLSLRSTFSSPTRRRDALFSPRLSARAVVPEEMPVDVETVKLFQASCRGMLHRLSMVDVLQNLTDQISSIESVQAIARGWIARKNYELRQTAYEEFLSWIIALQSTIRGSRFREQFKKQVLEAEALSTVPHIQACIRGQLLRLRVQRLHERLDETTSSIITVQTASRAYLSRHATVDLLDRLYEKIPQITILESILRGKLVRQPYQDLLKQIASFPTGLHTLCRGFLARKRFNTLLDQLQENETNIILVQSLARGTLQSTAFLDFLHKLKQKQPIWVQIQSSVRGLLLRKRIDYKLCQLDECCDSVIQLQSLSRAYLVEKQCAAIQAHLHSCKSSITGIQSAVRAILIRDDMNYLCLQLEEQIPEIIFLQSSIRGLFARQSYDRKMRSFRENMENPFLAQPIFRGRDQGQTYRELAEAKNPAVMTVKRFVHMLDDNDFDFEEDVEIEKYRQAIVKQVRENELVEEHINQLDIKIALLVKNKISLDDVLKHHVSMKHGQLPTDFVQANASTVNSLTNSSRKYIDLYQCLLYALQTNPEYLTRYLERLLNVQDSESAQKGAIHICLKIFGFGSNRREEILLLKALASFINMEVSRTVYIEDVVTENSFWGRIFAGFTANVRELRLWKILLGKIHRQILQNDELDLEVNPITIFQKLQGNDFEFSDANPKPSVSVAMKNIEVRNLYVFRLRALRKLCQAFLVTLAKNMDEIPYPLCFLSSILKQALEKQYPKAERHIILGVVGQFIYSTYIANVLVSPDNYRLVDGPITATQRNNLTALSSILREIFSLIPRTATELGFFRPLAEFIQVSKQDVAFLLERFVDIADPETYYDFDCFEDLTTTRKPILYLNKDDILTVYSMVTKFTDTLAPSEDDPLREIVRQLGPLNQQDSDFLNLRNEIKLELNPRYCTVEDPAAQERALVVQTKRYILFIIRVQNGTSLLNILVKPVTDDDEDVWQTILEEDITKHERRGESFDESLIDLSFTELKYAALQNVVQLEALGLARRENQYQDIVNSIALDIRTKSRRRIQRQRELETARQTLHGLIEKREYLESQLKSYNEYIEQAKETLQSKKGKKKLLPFSKQYFHIRDLRKSGQVPKFGSFKYTAIKLYERGVLVSMSSTLQQDKLYITLSSDEVGKFVLQAITQNVVIPNGTTELSLDDLLEAQYNKVLTLLVFNGRVKLNTNMLLQLIFSKFYA
InterPro domains: - IPR001715: Calponin homology domain (domain) [71-177]
- IPR000048: IQ motif, EF-hand binding site (binding_site) [399-717]
- IPR000593: RasGAP protein, C-terminal (domain) [1315-1452]
- IPR001936: Ras GTPase-activating domain (domain) [886-1210]
- IPR036872: CH domain superfamily (homologous_superfamily) [55-217]
- IPR008936: Rho GTPase activation protein (homologous_superfamily) [846-1225]
Interaction partners: - Rho family GTPase Cdc42
- Myosin II light chain
- Formin Cdc12
- Myosin type-2 heavy chain 1
- Cell division control protein Cdc15
- Myosin II regulatory light chain Rlc1
- Actin
- Actin Act1
- Myosin type-2 heavy chain 2
- Formin For3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport), GO:0006897 (endocytosis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0030427 (site of polarized growth), GO:0005933 (cellular bud), GO:0030054 (cell junction), GO:0140535 (intracellular protein-containing complex), GO:0000131 (incipient cellular bud site), GO:0001411 (hyphal tip), GO:0070161 (anchoring junction), GO:0005911 (cell-cell junction)
Protein: Decaprenyl diphosphate synthase subunit 2 Dlp1 (B6JZ41)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Sequence: MLTYVRPARLMPRFGRNSSTWSSVLLRAVGVVSQESKYHSDLLATLSEEMENLRSQLVQWTNSEPLLDTVIQPYTTSHARFFHPLLVLLMSRASTLDATPSKQQYQRYKQLSRITELIHAANAIHKSVQEHAKEAHSITKLKVLVGDYLLGKASVDLASLKDNSITELMASAIANLIEGNFPQTRDTMSIESERRRLRLQSAFLPAKACLCASILNRASEHISQACFEYGLHLGTAMQLRQSNPDKTEIRLDDEVNRAKKVLSVLPDVEVKQTLYEIADAIAANDG
InterPro domains: - IPR000092: Polyprenyl synthetase-like (family) [65-240]
- IPR008949: Isoprenoid synthase domain superfamily (homologous_superfamily) [34-281]
Interaction partners: - Tryptophan synthase
- Multifunctional tryptophan biosynthesis protein
- Squalene synthase
- Decaprenyl diphosphate synthase subunit Dps1
- Diphosphomevalonate decarboxylase
- Protein farnesyltransferase subunit beta
- Alkyl transferase
- ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyldiphosphate specific]
- Para-hydroxybenzoate-polyprenyltransferaseCoq2
- Atypical/ABC1/ABC1-A protein kinase Abc1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups), GO:0004659 (prenyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0042180 (cellular ketone metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901576 (organic substance biosynthetic process), GO:0044283 (small molecule biosynthetic process), GO:1901661 (quinone metabolic process), GO:0042181 (ketone biosynthetic process), GO:0006743 (ubiquinone metabolic process), GO:1901663 (quinone biosynthetic process), GO:0006744 (ubiquinone biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:1902494 (catalytic complex), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005739 (mitochondrion), GO:1990234 (transferase complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005740 (mitochondrial envelope), GO:0019866 (organelle inner membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031966 (mitochondrial membrane), GO:0005743 (mitochondrial inner membrane)
Protein: Tropomyosin (B6K811)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Sequence: MDKFREKLNSIRAEAEEALARAEAAEESLKEKEHELARKDQELASLHKKNEDLEEQVDQLEQELKDVKEQAESESNQQSLIDSLNRKIESLEEELENSDKSLRETTEKLRQIDINTEHTERKIQALEHERDDLEVRLEDTTDKYNKVKAELEEVNQALEDL
InterPro domains: - IPR000533: Tropomyosin (family) [1-161]
Interaction partners: - Rho-type GTPase activating protein Rga3
- Rho-type GTPase activating protein Rga4
- Actin
- Actin Act1
- Myosin type-2 heavy chain 1
- Alpha-actinin
- Myosin type-2 heavy chain 2
- D-lactate dehydratase
- D-lactate dehydratase
- Myosin II regulatory light chain Rlc1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0051015 (actin filament binding), GO:0008092 (cytoskeletal protein binding), GO:0003779 (actin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0003008 (system process), GO:0003012 (muscle system process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0036379 (myofilament), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043229 (intracellular organelle), GO:0043292 (contractile fiber), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0099512 (supramolecular fiber)
Protein: Vacuolar sorting protein (B6JWS3)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Sequence: MTQQESQTLLKYIFSLDPFRESRRRSLYSDFSNAIHRNPEGFRANMVAWKDALEKACYNGHWHHKLYIEFNDELRDSLFSTEYGRPLSLGAVANYWLDQGDWVTKNNLKGSVQPQNGNGSIIMGVLRWGFRTLGFTTSSEKKIPKQTYPNGKLFLLSNLQNLCISIISEAERLHTSYSSNIYSYPSFAEIFGKKLWAGHTLDEDELTAILLYLSGKYRRITYDKEVIKFILTPEEELLEQIDHSIAKLRQASFTTSQRLESLNDQIEKLTFKLKECLEQKKKKSALSLLRKRHFLFSNVEQKEGVLLQLDSLVSKIDEALDNRNIVDALSTGAESLGSILRSMGGATNVDLILQRVEEQTQVADEIAESLSAAAPLQEDEDIEKEWNKLVKEEQKEEDLVSLLERTSLRSPSHPITASEPEVKNPERVLEPAMQS
InterPro domains: - IPR005024: Snf7 family (family) [243-413]
Interaction partners: - Vacuolar-sorting protein SNF7
- Vacuolar sorting protein Vps24
- LEM domain-containing protein Heh1/Lem2
- Vacuolar sorting protein Vps20
- Vacuolar sorting protein Did4
- Vacuolar sorting protein Did2
- MVB sorting pathway protein
- Vacuolar sorting protein Vps60
- LEM domain-containing protein Man1
- ESCRT II complex subunit Vps25
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0051649 (establishment of localization in cell), GO:0046907 (intracellular transport), GO:1901575 (organic substance catabolic process), GO:0006810 (transport), GO:0009057 (macromolecule catabolic process), GO:0016192 (vesicle-mediated transport), GO:0016197 (endosomal transport), GO:0007034 (vacuolar transport), GO:0007041 (lysosomal transport), GO:0032509 (endosome transport via multivesicular body sorting pathway), GO:0071985 (multivesicular body sorting pathway), GO:0008333 (endosome to lysosome transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000922 (spindle pole), GO:0043229 (intracellular organelle), GO:0097431 (mitotic spindle pole), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0005819 (spindle), GO:0072686 (mitotic spindle), GO:0015630 (microtubule cytoskeleton)
Protein: TRF Taz1 (B6JYV6)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Sequence: MKTRIMATVSNENHRTSKEHEMKENATNSTTHLYGTKAKEKFVDANLIDYEDDEGNTSESSLPSLHEGISQTSQTPGALDHPSRRVSLDIRNSSTPKAPAADNESQLARDSMVLNDSSPPETPSRIGDLNNLQMKTLLTDMDLLAMRANSISAPLVRSVEGLPGQNRPLTAEGTELFIQKGFLLMEELRQIYNLSSGTLIFRCFKGWDKEFPDLYAHEESMSSLQYCTGIIDLFDKSFIYIALRTMLIDAMLVLENDEDLFQETFDIFIDVCIRVIQHYPVYRKRPLDLIETLIFGSLDHLKELGGSLWQSRRCEEQLKDALLDLKDDAGVKAADDDVFVRKGIQYFKKLRFANRLILPDSRIEHAIARLSSTRALIEHLQKRIMNRANDSSATIKRKISETPTNATKKPKNVIGAERSLNRYNEGFNPRILGMLQKQLNAIAADSSILSQREERIRMQIDHLREQLKLLQQGAVGQIQHLVSPTSTADSHLLETNEYACPTTDLSSPWFLYNSEQHSFSEADNSSTPMYDASDFPPVRDGNAPYSNRAMVMESSMEPPQQSKSRKMTGARRPRKTRQRWSAAQEDELFKMIHLHGCSWSKIQNIQKSHDGPLSVFSQVQLKDKARLVKAKYMKQNRLDELYSISHFWKNVTVGQAYCELHGINNHRKNDKDELPVTEKQT
InterPro domains: - IPR001005: SANT/Myb domain (domain) [576-631]
Interaction partners: - DNA-binding protein RAP1
- Pot1 associated protein Poz1
- Telomere length regulator protein Rif1
- Telomere maintenance protein Ccq1
- Telomerase reverse transcriptase
- Shelterin complex subunit TPP1/Est3 domain-containing protein
- DNA binding factor Trf1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0016032 (viral process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0019058 (viral life cycle), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0019079 (viral genome replication), GO:0039694 (viral RNA genome replication), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0090304 (nucleic acid metabolic process), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0019438 (aromatic compound biosynthetic process), GO:0018130 (heterocycle biosynthetic process), GO:0039689 (negative stranded viral RNA replication), GO:0016070 (RNA metabolic process), GO:0032774 (RNA biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098687 (chromosomal region), GO:0043229 (intracellular organelle), GO:0000781 (chromosome, telomeric region), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome)
Protein: BRO1 domain-containing protein (B6K5C1)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Sequence: MEIISINGKNSLPYDFQKFCKYLENEHCLNEDKLTQDINELALARDQLSKKRYSDNYLVLLDKYEAMLRVLEQKYSNAVPYPFAWSTSISPSRVEQFSSLYFEHGSLLFQRAAVCTQLAQECMQNDVVDSVKACQYLQASAGTFKFIYQKYVFPDSEDLRLELLKGYEHVCLAYAQACVLFKAIEKKSVRVSILAKIASQVAVYFTQAESYMRQAESVPNYIFVLLKTNYFYYKAIAHQHFAKVALESSKFGVQVGHLNCLIDACRNVLKQSSIPSTNTIKTNAQDLLTIVEPELTIAMRDNDLIHLEAVPTSKELASLEKIDMVRSIVPQNLEDEPKVNACFLDALVSTSVYLRYKNLSERAISLKKDAISKLETLTDAGNELVSLFEISLQKQTSSSFSQNAYNDIIHYSKEIKRLGGTLVLSEAENQLNQLIQKTTKTLTESKKLLQLDDSQDSALRLKYGTDRWKREATEHAARSLLLTLQEHELSLRNACEGKANLDTKLRKYTSVLLYLESDTKQLFSQLENNSNPPSADELRLREDVQSSLTTWKQIQSHRQELHSISLPENTLELLNRGGKEQAELLMKNFQQELHNQFNIEQQELEQSLLFEKIQAQLSQLQTMRSLTKKGNDIESLYDQLTDGYQRFIELREELTTGLKFVNDLYDLVHLSHGRCMKFCDSRNVEAKQIISNLESRVESPTKLPKAGVFDPTVHKIRFQKKRE
InterPro domains: - IPR038499: BRO1 domain superfamily (homologous_superfamily) [1-347]
- IPR025304: ALIX V-shaped domain (domain) [407-685]
- IPR004328: BRO1 domain (domain) [2-387]
Interaction partners: - Vacuolar-sorting protein SNF7
- Acid phosphatase
- BRO domain-containing protein 1
- Vacuolar sorting protein Vps20
- vesicle-fusing ATPase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0046907 (intracellular transport), GO:0051649 (establishment of localization in cell), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport), GO:0016197 (endosomal transport), GO:0032509 (endosome transport via multivesicular body sorting pathway), GO:0071985 (multivesicular body sorting pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0005576 (extracellular region), GO:0033643 (host cell part), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043657 (host cell), GO:0043227 (membrane-bounded organelle), GO:0043230 (extracellular organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0031982 (vesicle), GO:0020003 (symbiont-containing vacuole), GO:0033655 (host cell cytoplasm part), GO:0097708 (intracellular vesicle), GO:0030430 (host cell cytoplasm)
Protein: Rho-type GTPase activating protein Rga6 (B6JUV7)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Sequence: MSVNTSTPAFNAGTQFYLAHTSSLSSLQVSEKWQQSPNTNNCISHANTSVMAHSFLETFHTLAEAHRIPTVTINDMVPHCPATPTPDGRPYTSGGLIPFVSSSGNDEIDGSPNVRRTKRYSIRSSPKRSRSQLLHRHSVFVPSSPSSFQPMHSATLSSDRISSLNESADSANGNNLLGFASSESSLALRPKTSAYGSSVHTSQDSPDTADLKRAHRNSWTFFLRHPSTSHLQRKFSISGNSPSSTHHSRNLSSRTNLLASSRSVFGKDILALPDNESTFCEPDALPSHALPASLRVPHVFSQCITALISHGLAVPGIFRISGSGPVIRAIMDYYFEPPSFWYEDPEDLFQKIGEPTAIDIAGVLKRYILMLPGGLLGRQEVLDLLVSLHHAPNQQELPKNVWLEMTVLALAQIDSYRRFSVFASLFALLHLIVLKTQQVEQSLADIGESTYMRAEALGIVFGPLLLGMSDEPYSTKIDGAQLNDVMRFETEKVRLEAKIVENIINNWPGLVAEMRRLEVAAAFPDSPENVTKEENVTVTRNPSTIVEVPSSRALVSQRNSALFNSNVPADLFFTPMSTAFSFYPENDTRNQVSFSFADDSSLTNMQPEDPSVRQTSPLSPSLLEETTRAVLESNNDAGVTVSSSSNEKDLENQLTPAHVSEAEAIQSFIKSTSTLPLPTKNIRRAETVILSAPTSKATEDNVLSDRKLKARTVTAIPSDGTTSSKSDKKESKHGFSRFYKRINIFRRLFKKKKT
InterPro domains: - IPR000198: Rho GTPase-activating protein domain (domain) [283-511]
- IPR008936: Rho GTPase activation protein (homologous_superfamily) [212-516]
Interaction partners: - AMP-activated protein kinase beta subunit
- Tryptophan synthase
- CAMK/CAMKL/AMPK protein kinase Ppk9
- non-specific serine/threonine protein kinase
- Rho-type GTPase activating protein Rga4
- Rho-type GTPase activating protein Rga3
- non-specific serine/threonine protein kinase
- Multifunctional tryptophan biosynthesis protein
- non-specific serine/threonine protein kinase
- non-specific serine/threonine protein kinase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0008047 (enzyme activator activity), GO:0060589 (nucleoside-triphosphatase regulator activity), GO:0051020 (GTPase binding), GO:0030695 (GTPase regulator activity), GO:0005096 (GTPase activator activity), GO:0031267 (small GTPase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0035556 (intracellular signal transduction), GO:0007264 (small GTPase mediated signal transduction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005618 (cell wall), GO:0009277 (fungal-type cell wall)
Protein: Exocyst complex subunit Exo70 (B6K881)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Sequence: MQVGEYDTFQKNLVAVSKKVSDISLLLGSMEGRLKTLQQTTSKVHGDITNYNRISKNVNTALKRLETIREVYLQFSALEDQVKRCEQTDSEPMEQLDGVMETLRQICELKIHLENDNLSYLSSAIDRINELLKSGIQTLQSLCITQLSSFNHMNQDPIDVLDWKYQWAFPTVELKAFVSLIHSFDKDVLIPCSCSSEIDTLYISSRSEYLSGILQEVGKNVDVALLRNQASQNMSDEISIYSAALVRLLPLEANELIEIYGLADAKQLYPLIVNRVVDMVNTVFQQVFQIYNDRYVYDNYILFPMVGNLSTVITVLAKDMPFEDEALTMCLVRIKKKIEKLISSNIVTFYESICTNNTSLKLSLDRIDEETAGVTEYLSILCSSEHAFYLFQRIGNWGWRNEQNIPLDSPNHMADAAGIEIVTNYVMDCIENYIESVRVYAKATTQPPSFASAQVLLVFYHIDHALRALTLNETLYENLITRLSDCKQRFTSAYMDIWNKCSQNLLDATYTKSSSNKTGMAAKDRETLKERFRNFNEQITQVVEIHKAQVRFDPETAPTLLREVLKTVVPLYERFYDRYANSDFTKKREKYIKFGKTDLNTFITSAFEAS
InterPro domains: - IPR046364: Exocyst complex subunit Exo70, C-terminal (domain) [236-604]
- IPR016159: Cullin repeat-like-containing domain superfamily (homologous_superfamily) [93-608]
Interaction partners: - Exocyst complex component SEC15
- Exocyst complex component Sec3 PIP2-binding N-terminal domain-containing protein
- Exocyst complex component EXO84
- Exocyst complex subunit Sec10
- Exocyst complex subunit Sec6
- Exocyst complex component Sec8
- Exocyst complex component SEC5
- GTP-binding protein RHO3
- Rho family GTPase Cdc42
- F-box protein Pof6
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0008289 (lipid binding), GO:0005515 (protein binding), GO:0043168 (anion binding), GO:0019899 (enzyme binding), GO:0005543 (phospholipid binding), GO:0005546 (phosphatidylinositol-4,5-bisphosphate binding), GO:0051020 (GTPase binding), GO:0035091 (phosphatidylinositol binding), GO:0031267 (small GTPase binding), GO:1901981 (phosphatidylinositol phosphate binding), GO:1902936 (phosphatidylinositol bisphosphate binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0051649 (establishment of localization in cell), GO:0046907 (intracellular transport), GO:0051668 (localization within membrane), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport), GO:0016197 (endosomal transport), GO:0098876 (vesicle-mediated transport to the plasma membrane), GO:0032456 (endocytic recycling)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0060187 (cell pole), GO:0051286 (cell tip)
Protein: Fungal protein (B6JXC3)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Subcellular location: Endomembrane system; Multi-pass membrane protein
Sequence: MARIIRKTSLRSRIVNAPIDWVMHLAENIDSIEWEKLSEKWTIPCAIACNLVFILMRIFVRNMSFRQQRSSLFVSQKPSRGSWFQPVASCICFLLVLISIINAGYCLFYQKKKYTMTQPNAMSAPSTPNVYPVSNPVSPEGESMLQLVTWNPSSFHLQFACLFSPIHVLCLWIYSTSFLVLLLTFGFSLQLYYLGRKFQLLIKDQHYLHRQVFYEYDKKFVEPRLSVRKRDVAVSTRSGPGSATIEYYSPRKPIDSFLEHRSAPMSPITPSTSSAFRRSARARHSLATPIRADSSSIPFKRFPRLSEGPREL
InterPro domains: - IPR018819: Nur1/Mug154 (family) [3-277]
Interaction partners: - LEM domain-containing protein Heh1/Lem2
- Heat shock protein Pss1
- Hsp70-like protein
- Endoplasmic reticulum chaperone BIP
- Hamartin
- Hsp90-like protein
- NADH-dependent flavin oxidoreductase
- Heat shock protein S
- Heat shock protein S
- Heat shock protein Pdr13
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0010256 (endomembrane system organization), GO:0007029 (endoplasmic reticulum organization), GO:0071786 (endoplasmic reticulum tubular network organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098687 (chromosomal region), GO:0000785 (chromatin), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000775 (chromosome, centromeric region), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome)