wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Dual specificity protein kinase KNS1 (EC 2.7.12.1) (P32350)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Nonessential protein kinase.
Sequence: MSQNIQIGTRKRSRANMNNSTTTGPANNTSSNKTFLDNFEETRTNKLLDEMFARQNSFLTDNLRNSLDLNQADNPLRPRQHQHQLFLDNENAIELDEEPRIINTTINNSNNHNSSRVDEDADDDIIFIKEQPIQFSSPLILPSSSSINNNNNIVTSNNPGCGTAATSNSTYITTPKKFKKQRTISLPQLPLSKLSYQSNYFNVPDQTNAIVPRVTQTENELLHLTGSCAKTLEGNKAVNLTIAHSTSPFSNPPAQIASLPQSNLKKQIGSSLRKFTSNGSSESASSNKSNFKTDKDGHYVYQENDIFGSGGRFVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKTELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLYGRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDETHIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSAIFHYEYHPPVISTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVIGESLYPIHENLEHMAMMQRINGTPFPTDIIDKMFYKSKHKLGNSPSDLNSTVIKHFDRKTLSLQWPEKNKRGDTITTEKSMKRVLQSCDRLDIYISKVLKQDYGDSLSINWNLPPEKNWSLINSKLAWKRQTHSSSSSTTDELDKETFLFWYWFIDLLRKMFEFDPTKRITAKDALDHEWFNLGILDDGIATYNNTQG
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [305-721]
- IPR051175: Dual specificity CLK kinases (family) [226-721]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [436-448]
- IPR017441: Protein kinase, ATP binding site (binding_site) [319-343]
- IPR000719: Protein kinase domain (domain) [313-720]
Interaction partners: - Serine/threonine-protein kinase SKY1
- DNA polymerase delta catalytic subunit
- DNA-directed RNA polymerase III subunit RPC4
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0006793 (phosphorus metabolic process), GO:0036211 (protein modification process), GO:0006796 (phosphate-containing compound metabolic process), GO:0043412 (macromolecule modification), GO:0006468 (protein phosphorylation), GO:0016310 (phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Defensin D1 (Ns-D1) (P86972)
Organism: Nigella sativa (Black cumin)
Function: Antimicrobial peptide active against fungi, Gram-positive and Gram-negative bacteria. Inhibits growth of hyphae in the fungi A.niger (IC(50)=3.5 ug/ml), B.sorokiniana (IC(50)=3.0 ug/ml), F.oxysporum (IC(50)=9.5 ug/ml), F.graminearum (IC(50)=6.9 ug/ml), F.culmorum (IC(50)=6.9 ug/ml) and B.cinerea (IC(50)=27.4 ug/ml). Has no effect on spore germination. Destroys spores in germinated conidia by disruption of cell walls and membranes in A.niger and B.sorokiniana. Causes vacuolization of germinated macro- and microconidia in F.oxysporum, F.graminearum and F.culmorum. Strongly inhibits growth of P.infestans on potato tubers above concentrations of 13.6 ug/ml. Inhibits growth of Gram-positive bacteria C.michiganensis and B.subtilis and of Gram-negative bacteria P.syringae, E.carotovora and E.coli.
Subcellular location: Secreted {ECO:0000250|UniProtKB:P69241}.
Sequence: KFCEKPSGTWSGVCGNSGACKDQCIRLEGAKHGSCNYKPPAHRCICYYEC
InterPro domains: - IPR036574: Knottin, scorpion toxin-like superfamily (homologous_superfamily) [1-50]
- IPR008176: Defensin, plant (family) [1-24]
- IPR003614: Knottin, scorpion toxin-like (domain) [2-50]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0090729 (toxin activity), GO:0016247 (channel regulator activity), GO:0140678 (molecular function inhibitor activity), GO:0016248 (channel inhibitor activity), GO:0099106 (ion channel regulator activity), GO:0008200 (ion channel inhibitor activity), GO:0017080 (sodium channel regulator activity), GO:0019871 (sodium channel inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0001906 (cell killing), GO:0009605 (response to external stimulus), GO:0006950 (response to stress), GO:0031640 (killing of cells of another organism), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006952 (defense response), GO:0043207 (response to external biotic stimulus), GO:0009620 (response to fungus), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0050832 (defense response to fungus), GO:0042742 (defense response to bacterium), GO:0050829 (defense response to Gram-negative bacterium), GO:0050830 (defense response to Gram-positive bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: 7-methyl-GTP pyrophosphatase (m(7)GTP pyrophosphatase) (EC 3.6.1.-) (P0A729)
Organism: Escherichia coli (strain K12)
Function: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00528, ECO:0000305}.
Sequence: MPKLILASTSPWRRALLEKLQISFECAAPEVDETPRSDESPRQLVLRLAQEKAQSLASRYPDHLIIGSDQVCVLDGEITGKPLTEENARLQLRKASGNIVTFYTGLALFNSANGHLQTEVEPFDVHFRHLSEAEIDNYVRKEHPLHCAGSFKSEGFGITLFERLEGRDPNTLVGLPLIALCQMLRREGKNPLMG
InterPro domains: - IPR003697: Nucleoside triphosphate pyrophosphatase Maf-like protein (family) [1-193]
- IPR029001: Inosine triphosphate pyrophosphatase-like (homologous_superfamily) [1-194]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0046983 (protein dimerization activity), GO:0042802 (identical protein binding), GO:0043169 (cation binding), GO:0042803 (protein homodimerization activity), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0046872 (metal ion binding), GO:0016462 (pyrophosphatase activity), GO:0046914 (transition metal ion binding), GO:0030145 (manganese ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:0006066 (alcohol metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006766 (vitamin metabolic process), GO:0006790 (sulfur compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0034308 (primary alcohol metabolic process), GO:0042723 (thiamine-containing compound metabolic process), GO:0006767 (water-soluble vitamin metabolic process), GO:0072527 (pyrimidine-containing compound metabolic process), GO:0006772 (thiamine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: GIM5A protein (Q9N9D0)
Organism: Trypanosoma brucei brucei
Function: Not known
Subcellular location: Peroxisome membrane {ECO:0000256|ARBA:ARBA00046271}.
Sequence: MSAQAHTYLCDAWNRDKVMAIVQFLPMALEGPARTAGCESLALSLGNLARMGDAYRAVTRLSLLANALSKPTLTSLSKPTGDMVASRIDQLSHLFHIGFCLNENTAVLAGHGVFPKSLHRLSGVAVLCWMYTLVLGIVRQLYLFVKLRPRQASRGAGAGDDKKVPAYTYLELKRAFVNLLKLVCYFLFALTCLPEGKPQLLANASGPLVPLHVMVKALSPNPLHASNTVRGLLGLIASVCEFY
InterPro domains: - IPR008733: Peroxisomal biogenesis factor 11 (family) [13-193]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0007031 (peroxisome organization), GO:0048285 (organelle fission), GO:0016559 (peroxisome fission)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0042579 (microbody), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005777 (peroxisome), GO:0098588 (bounding membrane of organelle), GO:0031903 (microbody membrane), GO:0020015 (glycosome), GO:0005778 (peroxisomal membrane)
Protein: Collagen triple helix repeat-containing protein 1 (Q9D1D6)
Organism: Mus musculus (Mouse)
Function: May act as a negative regulator of collagen matrix deposition.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Sequence: MHPQGRAAPPQLLLGLFLVLLLLLQLSAPISASENPKVKQKALIRQREVVDLYNGMCLQGPAGVPGRDGSPGANGIPGTPGIPGRDGFKGEKGECLRESFEESWTPNYKQCSWSSLNYGIDLGKIAECTFTKMRSNSALRVLFSGSLRLKCRNACCQRWYFTFNGAECSGPLPIEAIIYLDQGSPELNSTINIHRTSSVEGLCEGIGAGLVDVAIWVGTCSDYPKGDASTGWNSVSRIIIEELPK
InterPro domains: - IPR057873: CTHRC1, C-terminal domain (domain) [103-240]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0003008 (system process), GO:0016043 (cellular component organization), GO:0050877 (nervous system process), GO:0009887 (animal organ morphogenesis), GO:0044085 (cellular component biogenesis), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0043933 (protein-containing complex organization), GO:0048880 (sensory system development), GO:0007600 (sensory perception), GO:0007423 (sensory organ development), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly), GO:0050953 (sensory perception of light stimulus), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0051259 (protein complex oligomerization), GO:0007601 (visual perception), GO:0051260 (protein homooligomerization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005576 (extracellular region), GO:0005615 (extracellular space), GO:0031012 (extracellular matrix)
Protein: ALBINO3-like protein 2, chloroplastic (Ath5) (Q8L718)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probably required for the insertion of integral membrane proteins into the chloroplast thylakoid membranes.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Sequence: MAVWRSCLRASSSRHRLSSLFFSHHLKPSSFISHSPPLFSPSPSPSPTCFSPLHRLLSSGPEFPIGSQEIIPTDDSSLPVLAVVDFLEGFHEFTGLPWWMIIASSTVAVRLALLPLLILQLKKLKTISELLPKLPMPIPETPTLKGSIDQFSHFLKESRAIGCPSFLWFFPYLSVQLPCFFLLMASIRKMSLDGHPGFDSGGVLWFQNLSDLPGGSFGPVFPILIATFHYINIQISFDTSTIRQTTGLTGLLMRYYKLYLEILSVPLFFVGYAIPQGSLVYWVTNSSVNIFQQLSLKHPTVGAKLGLLSQGATPGMGHSMEISESVIKYVDSDSKEQTLSLQTLTPEELLSLSVQVLSKGDKETSIQLLRLALEKDPGYVRGLVLMGQALLQKTQLSEATEYLELAISKLLDEDPSDAEDVELLMLASQWAGAAYVQQGKLKSGIIHLERVAKLREPGDPKSKEHYFEALLLLSSALYKEGQSDEAAKILRVVVDHNPAYKPLLEQCEDENELVSDLVSRRKDHF
InterPro domains: - IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [335-511]
- IPR001708: Membrane insertase YidC/ALB3/OXA1/COX18 (family) [74-400]
Interaction partners: - Large ribosomal subunit protein mL45
- AT2G34250 protein
- F9K20.24 protein
- SecY protein transport family protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0071840 (cellular component organization or biogenesis), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0051668 (localization within membrane), GO:0045184 (establishment of protein localization), GO:0008104 (protein localization), GO:0043933 (protein-containing complex organization), GO:0006996 (organelle organization), GO:0090150 (establishment of protein localization to membrane), GO:0061024 (membrane organization), GO:0072657 (protein localization to membrane), GO:0022607 (cellular component assembly), GO:0051205 (protein insertion into membrane), GO:0065003 (protein-containing complex assembly), GO:0007005 (mitochondrion organization), GO:0033108 (mitochondrial respiratory chain complex assembly), GO:0017004 (cytochrome complex assembly), GO:0033617 (mitochondrial cytochrome c oxidase assembly), GO:0008535 (respiratory chain complex IV assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Variant surface glycoprotein (VSG, atypical), putative (Q380U6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Sequence: MTPQATALLALALTAEQARGNIPAGANEQEFGALCAIVDLSRSDITINQFPDQTAALEGAVLALNMSLADESWQKRFSKDGAKKEWIKELPAGTADPGHWKKSWPKWAAAAARLADQGTAAEIKSSGFETLNPIERAGAKASVAQIAAEAQFLTQQIAEKENVGKKHTAATVKAALNEAIYGVKQEAPPDFEPTRNYDGLNTQAREAICVGLGSEAKTTTIAGAIYCICGQDNAQAEKVCARNQADTHKWTSITNAMTKDGFEEIVKHCAGPAKTHLTSSLLMGLITKIKNLIRRVGANAYMGALKTGSSCNGDKTQGICIKYAGYDGTPTKDFAAIPWAQKLLALHDDLRQQEKAIAEATALEQQLAVAKNKAYAAALLQKTAPPTAGQTSSDNVNRKGDQGTQPTNKCNQIVTEETCNKENECSYEKESDGTKRCKYNATKATANGVPVTQPQKGPAKTTENKCKWKPEKDFKSPDCKWDGKECKNSSIIANKQFAMIVSAFVAMVF
InterPro domains: - IPR025932: Trypanosome variant surface glycoprotein, B-type, N-terminal domain (domain) [10-368]
- IPR019609: Trypanosome variant surface glycoprotein, C-terminal (domain) [410-508]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response), GO:0042783 (evasion of host immune response), GO:0020033 (antigenic variation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Protein TusB (tRNA 2-thiouridine synthesizing protein B) (P45530)
Organism: Escherichia coli (strain K12)
Function: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
Subcellular location: Cytoplasm {ECO:0000305}.
Sequence: MLHTLHRSPWLTDFAALLRLLSEGDELLLLQDGVTAAVDGNRYLESLRNAPIKVYALNEDLIARGLTGQISNDIILIDYTDFVRLTVKHPSQMAW
InterPro domains: - IPR007215: Sulphur relay, TusB/DsrH (family) [1-95]
- IPR023526: Sulphur relay, TusB (family) [1-95]
- IPR027396: DsrEFH-like (homologous_superfamily) [1-95]
Interaction partners: - Sulfurtransferase TusD
- Protein TusC
- Sulfurtransferase TusE
- Sulfur carrier protein TusA
- tRNA-specific 2-thiouridylase MnmA
- Uncharacterized protein YheO
- Cysteine desulfurase IscS
- tRNA sulfurtransferase
- Iron-sulfur cluster assembly scaffold protein IscU
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0006950 (response to stress), GO:0009628 (response to abiotic stimulus), GO:0009408 (response to heat), GO:0009266 (response to temperature stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: RmlC-like jelly roll fold protein (Q8GYZ3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MSSKMVKSSEIVGKLNLRAHQEGGFFAETFRDSSVFLSTSQLPPTFKVDRAVSTSIYFLLPSGSVSRLHRIPMAETWHFYLGEPLTVVELYDDGKLKFTCLGPDLFEGDQKPQYTVPPNVWFGSFPTKDVHFSQDGALLKAEARDSENHFSLVGCTCAPAFQFEDFELAKRSDLLSRFPQHESLITMLSYPE
InterPro domains: - IPR011051: RmlC-like cupin domain superfamily (homologous_superfamily) [3-190]
- IPR039935: Uncharacterized protein YML079W-like (family) [2-191]
- IPR009327: Cupin domain of unknown function DUF985 (domain) [9-184]
- IPR014710: RmlC-like jelly roll fold (homologous_superfamily) [2-189]
Interaction partners: - UTP:RNA uridylyltransferase 1
- At5g49280
- mRNA-decapping enzyme-like protein
- Mitochondrial import receptor subunit TOM5 homolog
- Protein RRP6-like 3
- Leucine-rich repeat receptor-like serine/threonine-protein kinase BAM3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016853 (isomerase activity), GO:0016860 (intramolecular oxidoreductase activity), GO:0016861 (intramolecular oxidoreductase activity, interconverting aldoses and ketoses)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0006970 (response to osmotic stress), GO:0001101 (response to acid chemical), GO:1901700 (response to oxygen-containing compound), GO:0009414 (response to water deprivation), GO:0010035 (response to inorganic substance), GO:0009415 (response to water), GO:0010033 (response to organic substance), GO:1902074 (response to salt), GO:0009651 (response to salt stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Nuclear transport factor 2 (NTF-2) (Q57W07)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU369002}. Nucleus {ECO:0000256|RuleBase:RU369002}.
Sequence: MSFQEIGTGFIRQYYEFFSKNRTQLAGVYRPTSLMTWVGEQIQGGENIMARFANLSFDEALFKTEDIDCHPSLSGGVLVVVNGEVLLKGESHPLKFNDVFHLAQEGSQWYISNQIFRIVGGGGH
InterPro domains: - IPR018222: Nuclear transport factor 2, eukaryote (domain) [2-119]
- IPR032710: NTF2-like domain superfamily (homologous_superfamily) [2-119]
- IPR002075: Nuclear transport factor 2 domain (domain) [7-117]
- IPR045875: Nuclear transport factor 2 (family) [3-119]
Interaction partners: - GTP-binding nuclear protein
- DNA repair protein, putative
- MPN domain-containing protein
- Ribosomal protein
- DNA repair protein, putative
- Nucleoporin NSP1-like C-terminal domain-containing protein
- Nucleoporin
- NTF2-related export protein
- Crossover junction endonuclease MUS81
- Nucleoporin
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0051179 (localization), GO:0009987 (cellular process), GO:0051641 (cellular localization), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0033036 (macromolecule localization), GO:0044085 (cellular component biogenesis), GO:0046907 (intracellular transport), GO:0006403 (RNA localization), GO:0006810 (transport), GO:0051649 (establishment of localization in cell), GO:0016043 (cellular component organization), GO:0051236 (establishment of RNA localization), GO:0043170 (macromolecule metabolic process), GO:0050658 (RNA transport), GO:0071705 (nitrogen compound transport), GO:0071702 (organic substance transport), GO:0051169 (nuclear transport), GO:0043933 (protein-containing complex organization), GO:0010467 (gene expression), GO:0022607 (cellular component assembly), GO:0015931 (nucleobase-containing compound transport), GO:0006913 (nucleocytoplasmic transport), GO:0051028 (mRNA transport), GO:0006406 (mRNA export from nucleus), GO:0006405 (RNA export from nucleus), GO:0016973 (poly(A)+ mRNA export from nucleus), GO:0051168 (nuclear export), GO:0050657 (nucleic acid transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0012505 (endomembrane system), GO:0031967 (organelle envelope), GO:0005635 (nuclear envelope), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)