Protein: Cysteine repeat modular protein 4 (Q8IK84)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Not known
Sequence: MKNITFLVSFLIFLRSINANISITNFTYTNQKGDIKVEFFQTDYIAIFKLPFGGSHEQIFEISDDYIITNDKETNNCNIPNNNFGFVYSKSNSQNKFLIVQREYTTIYIKDKNNNCSLISKVEPSLYSFQTIEYKKEKIKLGTTTKCDEKMVEKLKIYIDLLNDMNLSEDKVCNQIIASSFIQNIEIIDCTVYIGSIFLRNNLNREEYYICIKKEDNNNKMKNNISLLINTIDLNNTLIMNTFYCNMERDICSIIINSIYFNNIPNITDDTLVLKAQCNIDSNPLINIDHVLREGYYTFHFRNPKIYFLQICIIDNLKKYRMLGKIYFLKAYEPIICFIGTPCVIKSFTVKENVQYVQNNIDNETFIFTNKKCDNENVNENMNMIETDYDMKELENHQHFYLFSKNPLTDEKYLCTSNNKKFLLLFNIVLIKLPEYNIHYSIINNVVINYSTLFFEYNNYLGPYVKYECSDKSIVPDEYNNFNNNKDNNFLLKNEELNFTIKFKAIIMRLCLKQNNYYYDIGKIYIENFINYKKISSLKDFIFNADVSLHADDINTKLLKFAIKEDHNCHSDQGFFVQSKDNFRADKKPFYKNIFINHTTVYESINQIILDKDIYYICMCSLHEKCYDNNNLIDYNVYTNISIQNEIQPLQNKKKFICKIFADCSFTINFENEYNNTSDIWVAKKGQSCNSKDIQVGIHVSHQNVKEINKEKINVTKVNFKIYYLISHIHYSYLFNKDIFICGNYRNQHFIVHIKSDFFLLYYALPFEEEINIKNVTQTNVATNTYEAQEKNINIQSFENVKQKFKRLFIYSYRDDAKSNLYKTMNINQDENQISNTIKFEIPNDHPTKYNEIYFINECHYDQGVIIYDHKRESNNIAINNDNNNNNNNHIIKSKELYWARKKRIYNKKLKKKENKNEIINIYNCSNEIMNNHTLTSILIFDGPLKPLDIYCYMELDCIHKENFSILNFDYSLFVEISDTQRIIIHIKESEGNNKEKLNKAEKIYFNDSKRTTELILSIPKHISKGLEPGPYKIIYTRKFKQFIHELYVGTFHFIGAPSQKYHLIRENEENIIIHGYFKNIENERIHILKHQNTCVLTNKDKNKKLLKSSEIEYILNEIKTNIQNCTYLDDTKLLCKNDLPVEGKFILCWCYNILNDQNNLCHNLNIYRPKITEVSSLLYSIDPILEISKSSLTNFLNYNIGDFFFIIDDDCKNIKNIKLKSKLNDEQNILDIYKHLQYPKKYDLCICIVQHNIPCDKEENFKNFYIKLNEQIYFTMEMGSIDEFNNKDKFIKDFTFSTDYLDQLKLNIVPVFVFLPGPVEYKEYVCFAGIPCNATIKIKRSAQTRLITGNKQIIGEKKDVANPYTGSYGNRNKANIKKGEEKKEQKRNDKKEGEIGYKKEGEIGYKKEGEIGHKKEDELGDKKEDNNEDQNQDNKQDKIENMNKDINKDKEIKTKETNIEEEEEVEEEEVEEEEEEEEEEEEEEEKEEKEEEEEQEEQFDHNEHEVKGADKNKDKNFNQNKGESQNVNPNTQQNQYDEQIISEEEQDNIENSLLGKHQYIYYTLNDTKECKNEYETVYKSNASSIYVSQEINYLHHEFIDGVYNLKIDIVPTDITKRYEICASFYEDDKYFYNIGNIIFYGIFNESNTLDIISGVPFSFEINQFYSKYDLFIRLIYEKHGDSKTCRLYNNNFENVFLEGTIERTIVQHDKKVLDNYITNYKWKDVTIILDTDNNNYMTSYQNVDGSYNLYVCSCYELTEGHCQSGNYFSTQVMKFYVHTVELKEPKMNSLMHFLKPFTLKLETTKILNGSIKVIPIDIISDLSKLCLELNLKNIYLKYQAEINEYEQTYNITINFLSQGFIICWCGKDNCKDHEYLTKVAFFRLNSPNFIDVHTDLNGNFSFHFLNQFVNINDRVRFVGQASSCLDDENVDLFNNHIVIKNVQNKKGKTSNGGNTKKEQQKNNNKINSNNNEEDENDNENKNERKDEDDNYESYSIDWEQIIEIFGKPRNIFKGINQNWTWVSENYKMKTSNEKYIKICYCFHFYYKNCKDTKNFLYIGLVHNHIWDSKTTIMQNELDTNYEISNMIYFNKDSIKFVAINSFNDLNRNVCDNINYEKNIIMPFFSGYNKFHNTTINQKNILNILKTYYHNEFIFILCYNTEYYKKKTNYLLTTKDMTELNDFTTYYNEEINTYNIIQSSFSYHSDIKDISTTNENIEKYEHMQLLLQNRGNTPNIFENYFYQKDVYKKNNMSIYNMNLYNMSPYVVYNNNKKKITNIQVKNRLKIILTKMYHMTSVDINEVIYYKGKGELLTDLNLQNIFILPKQKKVILCCYNDDYIEVIINDDNKIGMKKSNKIQELIDILKKYHPNFERNKKKQNDILEQFNNINDILFKYDYIRDVNKNQIYYDTGFFRNNIYIQLINQPFDLKIYGSNIQKKKTKDYILYIIEFHNICYNNMNKNGFFLEHKRYNEMENYIHFLQISMNKINNYKLCLYDKERDIYSNVGILNITDYFVIKESSFFDNEDIGNIKKKNMETDSYNYNNDNNYDGNYDNNYDNNYDQNNNKYYIKNYNQDVIKNVCLIMDNNTNQIIVIKGKGSFYFNLQIEKGIFIEKKGQKLNELFPDIKNHEPISCKNKKKNTIILTKTHIFFYTNNNDISFSTKHNLPFPYDIDFDDQYIYVNDLYLNKIARIQILSNKDNKTPIPIINNKQRSKRSIINHGHESQQNIQKTHQTYDHFTPLHKVEKKEILQNNNIVQLKENEFPITNLKNIEYSKNNIPNQKISSKDDIYKMSDFQAFINKYANLITTNSFRLYNYFEKKKYYGTLNYFIKRVWFNKVGPSREENYSTESKIEQNDKNNNNNNNNNINNNYNYNYNDLHNNNHNIILNSNNYNNNNQSSRHQNFIYSYHVSLDGKKKQSENLLTHSLNNFIQFFQNKKNSILKKEKEKRKNIPSYNIMYKNINHITNTLNKRKQQELTSSIIKKRTKRNVQEKRMSQSAYNELVLASIKKYTNKVEPAHFVNNKLDYLNYITNLKSPLNISVQNNILYILDSIKNTFFSYNLINKEIKELEKYDFNDHPLILKNPLHFSIYNGIITEYTEHKNNLAFVTQIDSNEIKVIDLNSSKKYKIIKAIKLRKGYKHNHINYVIGIKQKLLIITSQSQNIDHYKNIIYHYHFNSFDQYFSISFNYTFAKNYNANDNLYITPDIDKYSDNIIYFCFLNSNNKCTNIDELTKLSISHETGIITGKLNYFGTFSLKIFAKTYFQYKINTYSNLYSYCGISQEYNKTKSTCESCPIGTFWNSEKLLCENCQKYIENTSTLKNGSKLKTDCLCSPGYEYSDKSSKCEKCKPGYYKKSVGNFICIKGCPINEKSITYGAKSYAEMDCKCIEGYYRKEDKCVLCLSNYYCPGNELIKPCDKNKISKEGVIHKNDCICKENYIKDNKNNNCVYCASIAKILGKPIYCSLCDPIYFHEDIYKNIFLLPNNIHNYGLINNIYNYDEDLSLQGNIMKYAYFHKTTNIERNFTHYINIKNIYHTFNNNINNYDYLTNSKFAIEIDIPEPKKCIFCDSGYYIKKKKCISCTTKYCEGFNHNPKACPKNSVVNKMKASSIFDCSCKRGYGILNERRNAYSNTITCQICPQNFFKHIISDDSCFPCPLYTYTLNQGATSILQCLPKKGYFIYMFKSINIDYLRYKFDINTENRIYNYFENNNKIFDEDVYNFFLNKQYSKFFYNTENKTNTNNNHNNNNNNNHNHNNHNNNHNNHNNNNNNKYTKDNHFDNQVGNINKHTNNLQIKITENIYNIQYLEHLGFIKKTSLFYIYMILLRNIEERYNFNMDKMLKITCHINLHLKKNPHFTITYKKNLQECIDSCKTNIYCTGIEFSRKRVEYTQIILKNNKKIILGYFKCKQFYFQNIYDYSSYNLDSYLNEHIENQINIKSTLTYTNFIMRNKPDIIYTCSIDRDPKYLLYKNYKLVECVIGKFCPGNNTPYMISCPINSTTIIPASEDVNKCLCLKGYSYVGVTSYRCSLCDRGSYKNSVGNNKCDNCPLTFSTTHRGSTNIKDCSCTSGNYLTFDTLGNFIRTENMQHKNISDQYFVIPIKQESQPENEIKDDNKNINIYNANNINNHDIVYKTKMIKINLHKENDNHNDYMNNILKQTIGLCKPCTLENHYCEGGLESDITFNNKLIKGKFHTLPKKCPRGLGIPNIIKERNSINNCLCIHGKVQRTTENKNVECFPCPPNTFKENEYDNSCSGACPPFSTTFVGSSYENQCFCKNNYYLVSTDDENDTNGNSINNNKNIYNNNNIYNNNNNNNNNNNNNFNNKSDVKKKSCKICPIGAICNRGFNIYIYLKLLNDRSYNNINVIDHETPFPKYGYYAVYREKTNPTKSWDTLDDSAILNYVYPYHKLLLFIQKNIQKGNYFFLEKGNKFFLNDDFVEKMNEKSKYEEENANKFVTKSEIIHNVNTNNLKGKHNTLNNNNNNNNINKSSSFLNQNNYNNDIIQLSSYENNPFKNLSSTSEVSSNNNVISFIQNNDKTNNSTNDNNIENLVDIFNKYVQEAKELQIQNRKFERIPDIHPCTIPNRCLGTLINLCSDGSTGYQCNNCSKNYDMSYFKSKCKKCQNLFYEILHFILLKLLYYIIVIFICSLNGNILNKLHVSGILMRIWLNCSFTFIAYGFFIPNMNSFISKYWYLYKTAFSYHMKIFAYYLRVQCLLNSLNINLSYNQMWYIQKYMNICTPIFDSIFITILLFAVIHIYKFFFYKKNIDIFEQLLCTIPELNTLYKKNCIDNIHKVKNKKFANKVESFEENENQNKEKKNKKNIKRKNKAKNKHNNDNNDNNDDNDNNNDNNNDNNKININSKDEHINHFEKCSSITTILNNLELNNEEKNKESKKKKIFDIKKKTSIENIKENETNHLWNDTHNNVKNKESNINTTNISNNINYELKYIKNKEWYNIFLNKTIQYIYKEKKIFGLWHFIFTKNDNWFKNMGTFLNDTLPCYVLIMILSIPYILLELVQLTYCTPIKYKTQKTYFYLTYLITQKCSLSSKLFITGLIVTITMFALYIFLWILLLYLYSKRKRLNLFDLLTTNLLSGFRKGKGIFELIFLLKHILIVLLICFNIYYGLYYIVFLTLILITFAILEILSNPYDKRSFNILNKSLNIGNVLNIFFPLIIWGSFYWTYENFFIFPIFVIYAYHIYMFYHIVKEFTLSIHFIKTENIVNIQTIGYDPENIKNKNYKIYYKVMNKIKYFLNKNQKKNISNINENKDKHLNKNNNSKDHVKFEPIENIIKRYNLKLNKGILKDANNNNNNNNIKNMSDQVEDNKKDILFIKKNVLPVNVHNVASIWYDEQNEDLLFQMPYQNKFCLNMNNEANENNDQINDLTKDKTSEEENNNDHVNDPTKDQTNDEKKKNKNKKNKNNNNNENNCHSNDNSNNNNNKEVHKNDDNINHNNINNHNKSSNISTTNKKNYFNKFSDYIIDKRNKKSIKYFITSLMEVIEKFLDSSTHGFIYENWFDFTIRFAFVYISWIKKCNKKNNIMLPMNIQQLHIHMDLFIFTPIFPKNNSTCINEQNIQNYSKKKKIYNKINMYDEKIETGELLEKHNSFENTEIKISRSFGSHNYMPNIKNRKNNYDKKEDITSINDINVDIIKQDDQKEDSNINHLINEHNQKEPSQHIYNINDKNIMDYNIDENISKNNEKEKHIKIPPKNISITQKEYYNNNDIFNYSLDIFSSEMFNEKMFHSIISLFELYMAIKTLKLMNPHIFNKLYQMYNKKIITFDTSVMFYINKLRDDIKSEIEQIDKEINTGDTTEKERIQNYYYYKEELFKRKKLEEELLSKIKSLEECIEVNKRSQSLRNMLLTKKKKNNNLNNENLEEHINYIFSHLHNEGTYKLNHSQNMDKKN
InterPro domains: - IPR009030: Growth factor receptor cysteine-rich domain superfamily (homologous_superfamily) [3218-3417]
- IPR056048: Cysteine repeat modular protein A/B-like, DUF7631 (domain) [4329-4377]
- IPR011641: Tyrosine-protein kinase ephrin type A/B receptor-like (domain) [3629-4064]
- IPR033489: E3 ubiquitin-protein ligase RBBP6 family (family) [4232-5906]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0044403 (biological process involved in symbiotic interaction), GO:0051701 (biological process involved in interaction with host), GO:0044000 (movement in host), GO:0044409 (entry into host)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0043226 (organelle), GO:0005576 (extracellular region), GO:0033643 (host cell part), GO:0043657 (host cell), GO:0043227 (membrane-bounded organelle), GO:0043230 (extracellular organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0020003 (symbiont-containing vacuole), GO:0033655 (host cell cytoplasm part), GO:0030430 (host cell cytoplasm)