Protein: Phosphoserine aminotransferase 2, chloroplastic (AtPSAT2) (EC 2.6.1.52) (Q9SHP0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the plastidial phosphorylated pathway of serine biosynthesis (PPSB). Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine.
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Sequence: MAASTNSFLIGNQTQIPSLKPKSISQSFIHFTKPNTINLTTRTKSVSIRCASASTTVGSEQRVINFAAGPAALPENVLLKAQSDLYNWRGSGMSVMEMSHRGKEFLSIIQKAESDLRQLLEIPSEYSVLFLQGGATTQFAALPLNLCKSDDSVDYIVTGSWGDKAFKEAKKYCNPKVIWSGKSEKYTKVPTFDGLEQSSDAKYLHICANETIHGVEFKDYPLVENPDGVLIADMSSNFCSKPVDVSKFGVIYAGAQKNVGPSGVTIVIIRKDLIGNARDITPVMLDYKIHDENSSLYNTPPCFGIYMCGLVFDDLLEQGGLKEVEKKNQRKAELLYNAIDESRGFFRCPVEKSVRSLMNVPFTLEKSELEAEFIKEAAKEKMVQLKGHRSVGGMRASIYNAMPLAGVEKLVAFMKDFQARHA
InterPro domains: - IPR020578: Aminotransferase class-V, pyridoxal-phosphate binding site (binding_site) [248-267]
- IPR015421: Pyridoxal phosphate-dependent transferase, major domain (homologous_superfamily) [76-316]
- IPR015424: Pyridoxal phosphate-dependent transferase (homologous_superfamily) [62-419]
- IPR015422: Pyridoxal phosphate-dependent transferase, small domain (homologous_superfamily) [318-422]
- IPR022278: Phosphoserine aminotransferase (family) [60-421]
- IPR000192: Aminotransferase class V domain (domain) [64-410]
Interaction partners: - D-3-phosphoglycerate dehydrogenase 1, chloroplastic
- D-3-phosphoglycerate dehydrogenase 2, chloroplastic
- Phosphoserine phosphatase, chloroplastic
- D-3-phosphoglycerate dehydrogenase 3, chloroplastic
- Threonine synthase 1, chloroplastic
- Cysteine synthase, mitochondrial
- Cysteine synthase, chloroplastic/chromoplastic
- Cysteine synthase 1
- Bifunctional L-3-cyanoalanine synthase/cysteine synthase D2
- cysteine synthase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:0016740 (transferase activity), GO:1901363 (heterocyclic compound binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0005515 (protein binding), GO:0019842 (vitamin binding), GO:0046983 (protein dimerization activity), GO:0043168 (anion binding), GO:0042802 (identical protein binding), GO:0016769 (transferase activity, transferring nitrogenous groups), GO:0070279 (vitamin B6 binding), GO:0008483 (transaminase activity), GO:0042803 (protein homodimerization activity), GO:0030170 (pyridoxal phosphate binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006520 (amino acid metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0006082 (organic acid metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0008652 (amino acid biosynthetic process), GO:0016053 (organic acid biosynthetic process), GO:0043436 (oxoacid metabolic process), GO:1901605 (alpha-amino acid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0009069 (serine family amino acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process), GO:1901607 (alpha-amino acid biosynthetic process), GO:0009070 (serine family amino acid biosynthetic process), GO:0006563 (L-serine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009532 (plastid stroma), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009570 (chloroplast stroma), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle)