Protein: AICARFT/IMPCHase bienzyme family protein (Putative phosphoribosylaminoimidazolecarboxamide formyltransferase) (Q8RWT5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MLSSAATATSVSARSGDILCGLFRKKSVAPFRFTQPVYRTSLCPSFVAVRAMAESQTAQRNQPQSSGSSGEKQALISLSDKRDLASLGNGLQELGYTIVSTGGTASTLENAGVSVTKVEKLTHFPEMLDGRVKTLHPNIHGGILARRDVEHHMEALNEHGIGTFDVVVVNLYPFYEKVTAPGGISFEDGIENIDIGGPAMIRAAAKNHKDVLIVVDSGDYQAVLEYLKGGQSDQQFRRKLAWKAFQHVAAYDSAVSEWLWKQTEGKEKFPPSFTVPLVLKSSLRYGENPHQKAAFYVDKSLAEVNAGGIATAIQHHGKEMSYNNYLDADAAWNCVSEFENPTCVVVKHTNPCGVASRDDILEAYRLAVKADPVSAFGGIVAFNVEVDEVLAREIREFRSPTDGETRMFYEIVVAPKYTAKGLEVLKGKSKTLRILEAKKNDQGKLSLRQVGGGWLAQDSDDLTPEDISFNSVSDKTPTESELADAKFAWLCVKHVKSNAIVIAKNNCMLGMGSGQPNRVESLRIAFKKAGEEAKGAALASDAFFPFAWKDAVEEACQMGIGVIAEPGGSIRDQDAIDCCKKYGVSLLFTNVRHFRH
InterPro domains: - IPR024051: AICAR transformylase, duplicated domain superfamily (homologous_superfamily) [278-596]
- IPR016193: Cytidine deaminase-like (homologous_superfamily) [280-596]
- IPR011607: Methylglyoxal synthase-like domain (domain) [61-215]
- IPR036914: Methylglyoxal synthase-like domain superfamily (homologous_superfamily) [65-266]
- IPR002695: Bifunctional purine biosynthesis protein PurH-like (family) [65-596]
Interaction partners: - Adenylosuccinate lyase
- Adenylosuccinate lyase
- Adenylosuccinate synthetase, chloroplastic
- Phosphoribosylglycinamide formyltransferase, chloroplastic
- Inosine-5'-monophosphate dehydrogenase 2
- Probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial
- Inosine-5'-monophosphate dehydrogenase 1
- Phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic
- Formate--tetrahydrofolate ligase
- Serine hydroxymethyltransferase 3, chloroplastic
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016787 (hydrolase activity), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0016742 (hydroxymethyl-, formyl- and related transferase activity), GO:0016814 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines), GO:0019238 (cyclohydrolase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0019637 (organophosphate metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0006793 (phosphorus metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0006753 (nucleoside phosphate metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0019693 (ribose phosphate metabolic process), GO:0018130 (heterocycle biosynthetic process), GO:0090407 (organophosphate biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0072521 (purine-containing compound metabolic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0009259 (ribonucleotide metabolic process), GO:0009117 (nucleotide metabolic process), GO:0046390 (ribose phosphate biosynthetic process), GO:0006163 (purine nucleotide metabolic process), GO:0072522 (purine-containing compound biosynthetic process), GO:1901293 (nucleoside phosphate biosynthetic process), GO:0009165 (nucleotide biosynthetic process), GO:0006164 (purine nucleotide biosynthetic process), GO:0009150 (purine ribonucleotide metabolic process), GO:0009260 (ribonucleotide biosynthetic process), GO:0009152 (purine ribonucleotide biosynthetic process), GO:0046058 (cAMP metabolic process), GO:0009190 (cyclic nucleotide biosynthetic process), GO:0006171 (cAMP biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle)