Protein: Phosphatidate cytidylyltransferase (B6JVL2)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Subcellular location: Membrane; Multi- pass membrane protein
Sequence: MSKKRTRKQVRPEVERTANENEGLVSSSLANRKLDTVSNMVGKLREKPLIHKPSQNFIQRTVWTVIMLVFFFIILAMGPFWILVLVTVLQIGVYKEVIAIASVPSREKDLPLTKVVNWCFLITTLYYAYGESILRYFHHLLIVDSYLMPLATHHRFISFMLYTISFVLFVASLKKGNYKFQFSQFCWTHMTLLLVVGQAHFMINNIFEGLFWFFVPVCYVVCNDVFAYLCGKVFGKHPLIQLSPKKTVEGFVGGWVCTVVVGSLLSFMLMRSNYFICPTRDLSATIFSNIECVPNSVFLPKTYNVPLIMSRLFRFPRTLTLAPIYFHLAVFATFASLVAPFGGFFASGLKRAFKLKDFGDSIPGHGGLTDRVDCQLLNGAFVYMYVQSFISEKRGNVTELLEIAVTSLTSAEQLELFEDLKEYLISQGKLTVDAICQACR
InterPro domains: - IPR016720: Phosphatidate cytidylyltransferase, eukaryota (family) [9-430]
- IPR000374: Phosphatidate cytidylyltransferase (family) [347-373]
Interaction partners: - CDP-diacylglycerol--inositol 3-phosphatidyltransferase
- Triacylglycerol lipase
- CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
- Cardiolipin synthase/hydrolase fusion protein
- Uncharacterized protein
- Lipin Ned1
- CDP-diacylglycerol--serine O-phosphatidyltransferase
- Membrane bound O-acyltransferase
- Phospholipase
- Phosphatidate cytidylyltransferase Ptp4
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016779 (nucleotidyltransferase activity), GO:0070567 (cytidylyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0019637 (organophosphate metabolic process), GO:0006793 (phosphorus metabolic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0046486 (glycerolipid metabolic process), GO:0008610 (lipid biosynthetic process), GO:0006644 (phospholipid metabolic process), GO:0045017 (glycerolipid biosynthetic process), GO:0090407 (organophosphate biosynthetic process), GO:0006650 (glycerophospholipid metabolic process), GO:0046474 (glycerophospholipid biosynthetic process), GO:0008654 (phospholipid biosynthetic process), GO:0046471 (phosphatidylglycerol metabolic process), GO:0006655 (phosphatidylglycerol biosynthetic process), GO:0046488 (phosphatidylinositol metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0031090 (organelle membrane), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098827 (endoplasmic reticulum subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0005789 (endoplasmic reticulum membrane)