Protein: DNA-binding heavy metal response regulator (Q87Z28)
Organism: Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Function: Not known
Sequence: MHILLIEDDTKTGEYLKKGLGESGYKVDWTQHGADGLHLALENRYDLIVLDVMLPGIDGWQIIEVLRARQDVPVLFLTARDQLQDRIRGLELGADDYLVKPFSFTELLLRIRTILRRGVVREADHFHLADLELDLLRRRVTRQQQVIVLTNKEFALLHLLLRREGDVLSRAQIASEVWDMNFDSDTNVVDVAIKRLRSKVDLPYPVKLIHTVRGIGYVCEVRPCDASLP
InterPro domains: - IPR006291: Transcriptional regulatory protein CusR-like, heavy metal response (family) [3-218]
- IPR001789: Signal transduction response regulator, receiver domain (domain) [1-115]
- IPR039420: Transcriptional regulatory protein WalR-like (family) [1-217]
- IPR011006: CheY-like superfamily (homologous_superfamily) [1-172]
- IPR001867: OmpR/PhoB-type DNA-binding domain (domain) [123-221]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [119-221]
Interaction partners: - Sensor protein
- Sensor protein
- Sensor protein
- DNA-binding heavy metal response regulator
- DNA-binding heavy metal response regulator
- histidine kinase
- histidine kinase
- histidine kinase
- histidine kinase
- histidine kinase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0003676 (nucleic acid binding), GO:0001216 (DNA-binding transcription activator activity), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0048522 (positive regulation of cellular process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0048523 (negative regulation of cellular process), GO:0009892 (negative regulation of metabolic process), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0009891 (positive regulation of biosynthetic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0051252 (regulation of RNA metabolic process), GO:0051253 (negative regulation of RNA metabolic process), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0010468 (regulation of gene expression), GO:1902680 (positive regulation of RNA biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:1902679 (negative regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903507 (negative regulation of nucleic acid-templated transcription), GO:0045893 (positive regulation of DNA-templated transcription), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045892 (negative regulation of DNA-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0032993 (protein-DNA complex)