Protein: Nucleobase-ascorbate transporter 8 (AtNAT8) (Q8VZQ5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Cell membrane {ECO:0000269|PubMed:16982705}; Multi-pass membrane protein {ECO:0000269|PubMed:16982705}.
Sequence: MAGDGVENAKPPQKQEDLQPHPVKDQLYGITYCLTSPPPWPETILLGFQHYLVMLGTTVLIPTMLVSKIDARNEDKVKLIQTLLFVSGINTLFQSFFGTRLPAVIGASYSYVPTTMSIVLAARYNDIMDPQKRFEQIMRGIQGALIIASFLHILVGFSGLWRNVTRFLSPLSAVPLVAFSGFGLYEQGFPMLAKCIEIGLPEIILLVIFSQYIPHLMQGETCSNFFHRFAVIFSVVIVWLYAYILTIGGAYSNTEINTQISCRTDRAGIISASPWIRVPHPIQWGGAPTFNAGDIFAMMAASFVSLVESTGTYIAVSRYASATPIPPSVLSRGIGWQGFGILLCGLFGAGNATSVSVENAGLLAVTRVGSRRVIQVAAGFMIFFSILGKFGAIFASIPAPIVAALYCLFFSYVGAGGLSLIQFCNLNSFRTKFILGFSIFMGLSIPQYFYQYTTLETYGPVRTSATWFNNIINVPFSSKAFVSGILAFFLDTTLPPKDKTTKKDRGLVWWKRFKSFQSDNRSEEFYSLPLNLSKYFPSH
InterPro domains: - IPR006043: Nucleobase cation symporter 2 family (family) [42-448]
Interaction partners: - Purine-uracil permease NCS1
- Cytoplasmic tRNA 2-thiolation protein 2
- Polyketide cyclase / dehydrase and lipid transport protein
- Amino acid transporter AVT6D
- Protein LOW PHOTOSYNTHETIC EFFICIENCY 1
- Probable sodium/metabolite cotransporter BASS6, chloroplastic
- Uridine 5'-monophosphate synthase
- Putative actin-5
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0015205 (nucleobase transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0022853 (active monoatomic ion transmembrane transporter activity), GO:0005345 (purine nucleobase transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0015291 (secondary active transmembrane transporter activity), GO:0015293 (symporter activity), GO:0015294 (solute:monoatomic cation symporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0009987 (cellular process), GO:0055085 (transmembrane transport), GO:0051234 (establishment of localization), GO:0098739 (import across plasma membrane), GO:0006810 (transport), GO:0072530 (purine-containing compound transmembrane transport), GO:0072531 (pyrimidine-containing compound transmembrane transport), GO:0098657 (import into cell), GO:0071705 (nitrogen compound transport), GO:0071702 (organic substance transport), GO:0015851 (nucleobase transport), GO:0006863 (purine nucleobase transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0055044 (symplast), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0012505 (endomembrane system), GO:0030054 (cell junction), GO:0030312 (external encapsulating structure), GO:0005773 (vacuole), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0009506 (plasmodesma), GO:0070161 (anchoring junction), GO:0043227 (membrane-bounded organelle), GO:0005618 (cell wall), GO:0043231 (intracellular membrane-bounded organelle), GO:0009505 (plant-type cell wall), GO:0005911 (cell-cell junction)