Protein: Ribosome biogenesis protein BOP1 homolog (Q384Z1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Nucleus, nucleolus {ECO:0000256|HAMAP-Rule:MF_03027}. Nucleus, nucleoplasm {ECO:0000256|HAMAP-Rule:MF_03027}.
Sequence: MVKKREPTSRVTSRVHKTPSPSPRAVDDSGKQKPDLSTTPPPSPGEGGNGDEVLTSSQTNATDLRDELIWSDRESDDEVFLFPDAQELVEPQGGPDCDVIRIGATQKLDESDSSEDEATLNRVGDIPLEWYKDEAHYGYDVEGRKLMKSERSALERLLEATDDPNAMRTIYDALHDEKKVLSNADLQMIFNLQRNRTPNPNYNMYEDVAVDTVEFDPLNHPLARSAGPSKRKFLPSDRDMKTIAKMVRRMMKEDKEKENKPKDETESETTILWDDGKVVMDTHTHFKYHNRVPKPKAAPPGTYESYRPPPEYLPSERAKERFARLRAIDKKEHFLPRAFDALRHVPFYNHTIQDRYQRCLDLAFFPRAQRTRLVVDPSKLLPELPDPRDLRPYPERLSFQYKGHTATVRSVAVNPNGQYLATACDDHLVRVYEVMTGRLMKRYDMGAPVQQVEFCPVKTLNILAVAVEYSLVFIVPRFAAHELVNENTLRHLRAPGTAVNNTEVEQVVGGEVSLGGGGITQAALDKDETAHSILQDLHDVEERDKRAEFFDASAKERRAGIVLKIALHAKVKRFTFHARGDYLCALCPKDHVKYRQTVMLQLSKRKVFCPFRKFSEVVTDCKFHPREPLFFLSTTNSVRMYNLLAHKLQRRYKAPGGITTCLSIHTEGDNFLVGDTTSHTQWYDCDFSDKPYKRMRSHKGVVNAVAFHTNTNAYPLFASGAADGQVHVFHGMVYDDYNKNALLVPVKILKHRRAVYSVAWHPTLPWIFTSTEDGVVSAWTE
InterPro domains: - IPR001680: WD40 repeat (repeat) [394-781]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [384-781]
- IPR028598: WD repeat BOP1/Erb1 (family) [1-780]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [396-780]
- IPR012953: BOP1, N-terminal domain (domain) [131-394]
Interaction partners: - Ribosome biogenesis protein NSA1
- rRNA processing protein, putative
- NLE domain-containing protein
- Pescadillo homolog
- Ribosome assembly factor mrt4
- Nucleolar complex protein 2
- Ribosome biogenesis protein NSA2 homolog
- Ribosome biogenesis protein, putative
- Nucleolar protein, putative
- Nucleolar GTP-binding protein 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0042254 (ribosome biogenesis), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0042273 (ribosomal large subunit biogenesis), GO:0034470 (ncRNA processing), GO:0006364 (rRNA processing), GO:0034660 (ncRNA metabolic process), GO:0016072 (rRNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)