Protein: RNA helicase (EC 3.6.4.13) (O83538)
Organism: Treponema pallidum (strain Nichols)
Function: Not known
Sequence: MFSYKQLPVYSQKDKILSALAHHHVIVVESPTGSGKTTQLPLILHEAGYNEGGAIGVTQPRRIAVLSVSEFIAKQVLHVQPGIVGYKMRFEDHTDVETKIKVMTDGILLQEMKLDPLLSKYSIIMVDEAHERSLNIDFILGLLKRVLQQRHDFRIVISSATINTAMFSRYFNECPVIKIDAVAYPVTVIFDPPDTPASTHTKEAEAALLEKIVCIVERVIASRDKGAILIFLPGERSIKNCITRLSHERWFRKLFLLPLYGRLSKEEQEQVFNRAPFGKRKVVIATNIAETSITIDDVTTVIDSGLVKLNSYNPLSYTASLDETPISQASCNQRRGRAGRVRAGTCYRLYSRDDFEQREPYTLEEIYRTDLSEVVMRMAELGIHDFEHFDFISPPGTHGIIGAEDTLRLLGALEDDRSLSEIGKMMCLFPLGPRQSRMIVEALRRYPHSIDDVLIAAAFLSARSPLIFSEDQEEKTKKAHGTFSDPMGDFVSFLRIYRAYAQENNKHSFCQHFYLDERIMAEISNIKEQLELIVSGMGFPLLTGGTVEEYLICVGTGMIQFVCVQEHRDSYRSLTAECIHIHPGSCVYKDRPKFIVAGEIVRTSRMYAMSVSPLSKKIAELIAPALLERRGRAEKHGTSPTRAAFLKKSTLRKGPRKRRVRVGRASLR
InterPro domains: - IPR011709: DEAD-box helicase, OB fold (domain) [553-625]
- IPR002464: DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site (conserved_site) [122-131]
- IPR007502: Helicase-associated domain (domain) [402-494]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [3-517]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [5-189]
- IPR011545: DEAD/DEAH-box helicase domain (domain) [14-163]
- IPR048333: Helicase associated domain (HA2), winged-helix domain (domain) [403-431]
- IPR001650: Helicase, C-terminal domain-like (domain) [207-382]
Interaction partners: - Probable peptidyl-prolyl cis-trans isomerase
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS11
- Cytidylate kinase
- Small ribosomal subunit protein uS4
- Uncharacterized protein TP_1029
- RNA helicase
- RNA-binding protein, putative
- Ankyrin, putative
- Putative ankyrin repeat-containing protein TP_0502
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0008380 (RNA splicing), GO:0006397 (mRNA processing), GO:0016071 (mRNA metabolic process), GO:0000398 (mRNA splicing, via spliceosome), GO:0000375 (RNA splicing, via transesterification reactions), GO:0000377 (RNA splicing, via transesterification reactions with bulged adenosine as nucleophile)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)