Protein: Interferon regulatory factor 8 (A0A8I5Y754)
Organism: Rattus norvegicus (Rat)
Sequence: MCDRNGGRRLRQWLIEQIDSSMYPGLIWESEEKTLFRIPWKHAGKQDYNQEVDASIFKPSVDEYMGIAKRSPSPPEACRSQILPDWWAQQPNAGLPLVTGYTAYDAHHSALSQMVINFYYGGKLVGQATTTSLEGCRLSLSQPGLPKLYGPDGLEPVCFPAADTIPSERQRQVTRKLFGHLERGVLLHSNRKGVFVKRLCQGRVFCSGNAVVCKGRPNKLERDEVVQVFDTNMFLRDLQQFYATQSRLPDSRVVLCFGEEFPDTAPLRSKLILVQVEQLYARQMVEEAGKSCGAGSLMPALEEPQPDQAFRMFPDICTSHQRPFFRENQQITV
InterPro domains: - IPR019471: Interferon regulatory factor-3 (domain) [244-422]
- IPR008984: SMAD/FHA domain superfamily (homologous_superfamily) [245-458]
- IPR001346: Interferon regulatory factor, DNA-binding domain (domain) [45-157]
- IPR017855: SMAD-like domain superfamily (homologous_superfamily) [239-451]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [50-156]
- IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [51-156]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0023056 (positive regulation of signaling), GO:0042221 (response to chemical), GO:0048584 (positive regulation of response to stimulus), GO:0019222 (regulation of metabolic process), GO:0051240 (positive regulation of multicellular organismal process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0009893 (positive regulation of metabolic process), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0051239 (regulation of multicellular organismal process), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010604 (positive regulation of macromolecule metabolic process), GO:1901698 (response to nitrogen compound), GO:0010646 (regulation of cell communication), GO:0070887 (cellular response to chemical stimulus), GO:0009966 (regulation of signal transduction), GO:0060255 (regulation of macromolecule metabolic process), GO:0010647 (positive regulation of cell communication), GO:0001819 (positive regulation of cytokine production), GO:0001817 (regulation of cytokine production), GO:0010033 (response to organic substance), GO:0071310 (cellular response to organic substance), GO:0043331 (response to dsRNA), GO:0010628 (positive regulation of gene expression), GO:1902533 (positive regulation of intracellular signal transduction), GO:0014070 (response to organic cyclic compound), GO:1902531 (regulation of intracellular signal transduction), GO:0010468 (regulation of gene expression), GO:0043122 (regulation of I-kappaB kinase/NF-kappaB signaling), GO:0043123 (positive regulation of I-kappaB kinase/NF-kappaB signaling), GO:0043330 (response to exogenous dsRNA), GO:0071359 (cellular response to dsRNA), GO:0071407 (cellular response to organic cyclic compound), GO:0071360 (cellular response to exogenous dsRNA)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)