Protein: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1) (P62874)
Organism: Mus musculus (Mouse)
Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity).
Sequence: MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
InterPro domains: - IPR019775: WD40 repeat, conserved site (conserved_site) [157-171]
- IPR001680: WD40 repeat (repeat) [44-340]
- IPR020472: PAC1/LIS1-like, WD-40 repeat (repeat) [70-213]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [1-340]
- IPR001632: G-protein beta subunit, WD40 repeats (domain) [51-124]
- IPR016346: G-protein subunit beta 1-5 (family) [1-340]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [4-340]
Interaction partners: - Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Guanine nucleotide-binding protein G
- Adhesion G protein-coupled receptor L3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007186 (G protein-coupled receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0098552 (side of membrane), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0098796 (membrane protein complex), GO:0043209 (myelin sheath), GO:0001750 (photoreceptor outer segment), GO:0001917 (photoreceptor inner segment), GO:1902494 (catalytic complex), GO:0019898 (extrinsic component of membrane), GO:0036477 (somatodendritic compartment), GO:0031090 (organelle membrane), GO:0019897 (extrinsic component of plasma membrane), GO:0042622 (photoreceptor outer segment membrane), GO:0120025 (plasma membrane bounded cell projection), GO:1905360 (GTPase complex), GO:0098562 (cytoplasmic side of membrane), GO:0098797 (plasma membrane protein complex), GO:0098590 (plasma membrane region), GO:0097447 (dendritic tree), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0031253 (cell projection membrane), GO:0005929 (cilium), GO:0098588 (bounding membrane of organelle), GO:0031234 (extrinsic component of cytoplasmic side of plasma membrane), GO:0030425 (dendrite), GO:0009898 (cytoplasmic side of plasma membrane), GO:0043005 (neuron projection), GO:0005834 (heterotrimeric G-protein complex), GO:0060170 (ciliary membrane), GO:0097733 (photoreceptor cell cilium), GO:0097730 (non-motile cilium), GO:0097731 (9+0 non-motile cilium)