Protein: Tumor necrosis factor (TNF-alpha) (Q9DEP9)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
Sequence: MEGYAMTPEDMERGLENSLVDSGPVYKTTVTAVAERKASRGWLWRLCGVLLIAALCAAAALLFAWCQHGRLATMQDGMEPQLEIFIGAKDTHNTLKQIAGNAKAAIHLEGEYNPNLTADTVQWRKDDGQAFSQGGFKLQGNQILIPHTGLFFVYSQASFRVKCNGPGERTTPLSHVIWRYSDSIGDKGNLLSGVRSVCQQNYGNDESNIGEGWYNAVYLSAVFQLNEGDKLWTETNRLTDVEPEQGKNFFGVFAL
InterPro domains: - IPR006053: Tumour necrosis factor (family) [123-254]
- IPR006052: Tumour necrosis factor domain (domain) [104-255]
- IPR008983: Tumour necrosis factor-like domain superfamily (homologous_superfamily) [103-255]
Interaction partners: - TNFR-Cys domain-containing protein
- TNFR-Cys domain-containing protein
- TNFR-Cys domain-containing protein
- TNFR-Cys domain-containing protein
- TNFR-Cys domain-containing protein
- TNFR-Cys domain-containing protein
- TNFR-Cys domain-containing protein
- TNFR-Cys domain-containing protein
- TNFR-Cys domain-containing protein
- TNFR-Cys domain-containing protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0046983 (protein dimerization activity), GO:0042803 (protein homodimerization activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0009607 (response to biotic stimulus), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0002682 (regulation of immune system process), GO:0071840 (cellular component organization or biogenesis), GO:0051050 (positive regulation of transport), GO:0051707 (response to other organism), GO:0040012 (regulation of locomotion), GO:0048522 (positive regulation of cellular process), GO:0051049 (regulation of transport), GO:0044085 (cellular component biogenesis), GO:2000145 (regulation of cell motility), GO:0043207 (response to external biotic stimulus), GO:0002685 (regulation of leukocyte migration), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0009617 (response to bacterium), GO:0050766 (positive regulation of phagocytosis), GO:0034762 (regulation of transmembrane transport), GO:0060255 (regulation of macromolecule metabolic process), GO:0016043 (cellular component organization), GO:0034764 (positive regulation of transmembrane transport), GO:1901700 (response to oxygen-containing compound), GO:0060627 (regulation of vesicle-mediated transport), GO:0010033 (response to organic substance), GO:0010827 (regulation of glucose transmembrane transport), GO:0009743 (response to carbohydrate), GO:0050764 (regulation of phagocytosis), GO:0032496 (response to lipopolysaccharide), GO:0033993 (response to lipid), GO:0002237 (response to molecule of bacterial origin), GO:0010628 (positive regulation of gene expression), GO:0010828 (positive regulation of glucose transmembrane transport), GO:0043933 (protein-containing complex organization), GO:0030334 (regulation of cell migration), GO:0010468 (regulation of gene expression), GO:0022607 (cellular component assembly), GO:0046326 (positive regulation of glucose import), GO:0065003 (protein-containing complex assembly), GO:0046324 (regulation of glucose import), GO:0051259 (protein complex oligomerization), GO:0051260 (protein homooligomerization), GO:0070206 (protein trimerization), GO:0070207 (protein homotrimerization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)