Protein: Uncharacterized helicase C15C4.05 (EC 3.6.4.-) (O60114)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}.
Sequence: MAKKKSKASNSARGYATTSIPSRSASSPANKNQVKGEKNNKTQKVEPKNAFKVENQSNDIGVDTVDAFDHLLLDKTLPTIDAETEVIKNTSLSNSKSFLHSWQTDIRLRKNDNVLGLTEDEIQQILKTFRDSWKSSLKESYAFSNRSSFSLRKRYLWTTFLSLKGMGFEESEIFGAFSSIPIVSIDEYITWMITENLINSEPSNSSFSYEVQPSNYTTFCRMLDEPLPANNPVQSNSRLVPLMKDFSNDIKHTPNKETQPSNQVDDSLKSKDSKPLTMSEVLTQLPEDDIPFDDPFDLTSQYVKVKLKMLRLQIANKKNSEEFSTLNLQLESITSQYLFSSKEAEIVFRKSRIEFMNKLKALQQKLENERIVEEIKKNGIQEDSQSTDDSSKDDDNNSESNDMSPHNDAETRADDDAYLMGDLFNQEEEDIQDTENDLLNANYTLLPLTTDKSGTRPSTTLQYELHKIGSNIKAEFKTMPIGKIGYQSTCFVRCSTGQKTFSDLKTVLPTATLAADYISMIVLFRLMANFTKISLQTFPKSFKEVYGKFSAEKQNTDLAEDAKISEKLDSIIKSKELETPTSATTSKLMAPMDNIGKFSGFERPPETLLNKWRQQLESESAEKFKVFRNQLPATMFRETIIDAVNNSQLLIISGDTGCGKSTQIPAFLLENSTKNGKAVKIYVTEPRRISAISLANRVSQELGGNPPSARSHELVGYSVRLDSKCTPLTPLTYVTTGTFLRLLEVGNEIESVTHLIIDEVHERSIDSDLLLIHVLHLLKQHPHLKIIIMSATLNAEKFQLYFEGSNLITIPGKTYPVHRFYLEDILSQFGNDKSFGNAAGQDVIEEDDYETDQQDASISNKSAEDAIVEMNLIPAWYNEKAINYGLIVYLLKYIFTEGDPKFSKCVLVFLPGISEILRVKSLIEDMPMFRNHRKFCIYMLHSTLSSAQQQSVFNIPPKGCRKIVLSTNIAETGVTIPDVTCVIDTGVHREMRYNSRRHLSRLTDTFVSKANAKQRSGRAGRVQEGICYHLFSKFKHDTQFLSYQTPEILRLNLQEVVLRVKMCQMGDVQDVLGKALDPPSSTNIIRALEKLHQVGALSENEKLTKLGKFLSQLPVDANLGKILVLGCFYKCVDAASSIVAMLTIGSPFRKSVDNEFSANKARLSFAKENTRSDLVLMYYAYCAWREICLSPLGPDEDSFAKEKYLNLEALSMTESLKIQLLSELKDMKLLGASDVDTCKSLKRSICRRFAVIPKEHDINSGNAEILCGVIAASLYPNILRYDYEKRQWSTLSTNKRVRILDVSVNNRSELPNMPSKFVAYTNMMSSTRASEYVNETTMVTLRQLLMMCGLKVENRVSVGQAKLDNFTVYFENVYVSASLSILRRFIETSLNEFFAEPDKRLLNSHLEVIVNIVSRLNYGTKFQKRLKD
InterPro domains: - IPR011709: DEAD-box helicase, OB fold (domain) [1267-1349]
- IPR007502: Helicase-associated domain (domain) [1086-1178]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [597-1186]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [629-820]
- IPR011545: DEAD/DEAH-box helicase domain (domain) [638-796]
- IPR048333: Helicase associated domain (HA2), winged-helix domain (domain) [1087-1115]
- IPR001650: Helicase, C-terminal domain-like (domain) [886-1064]
Interaction partners: - ATP-dependent RNA helicase ded1
- ATP-dependent RNA helicase eIF4A
- Eukaryotic translation initiation factor 5B
- AP-2 complex subunit mu
- Probable eukaryotic translation initiation factor 5
- Eukaryotic translation initiation factor 4 gamma
- AP-1 complex subunit beta-1
- AP-2 complex subunit beta
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0044877 (protein-containing complex binding), GO:0016887 (ATP hydrolysis activity), GO:0016787 (hydrolase activity), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0043021 (ribonucleoprotein complex binding), GO:0043022 (ribosome binding), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity), GO:0017111 (ribonucleoside triphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0042254 (ribosome biogenesis), GO:0042274 (ribosomal small subunit biogenesis), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0034470 (ncRNA processing), GO:0030490 (maturation of SSU-rRNA), GO:0006364 (rRNA processing), GO:0034660 (ncRNA metabolic process), GO:0016072 (rRNA metabolic process), GO:0000462 (maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA))
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)