Protein: Mitochondrial import inner membrane translocase subunit TIM9 (Q6FRT3)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Function: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Intermembrane side {ECO:0000250}.
Sequence: MDQLNAKEQQEFQKLVEQKQMKDFMRLYSGLVERCFTDCVNDFTSSKLTSKEESCILKCSEKFLKHSERVGQRFQEQNAALGQGLGR
InterPro domains: - IPR035427: Tim10-like domain superfamily (homologous_superfamily) [1-87]
- IPR050673: Mitochondrial import inner membrane translocase subunit (family) [7-80]
- IPR004217: Tim10-like (domain) [14-76]
Interaction partners: - Mitochondrial import inner membrane translocase subunit
- Mitochondrial import inner membrane translocase subunit TIM22
- Mitochondrial import inner membrane translocase subunit
- Candida glabrata strain CBS138 chromosome J complete sequence
- Candida glabrata strain CBS138 chromosome L complete sequence
- Mitochondrial import inner membrane translocase subunit TIM54
- Mitochondrial import inner membrane translocase subunit TIM8
- Mitochondrial import inner membrane translocase subunit TIM13
- Succinate dehydrogenase cytochrome b small subunit
- Mitochondrial import inner membrane translocase subunit TIM23
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0009987 (cellular process), GO:0051641 (cellular localization), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0033036 (macromolecule localization), GO:0046907 (intracellular transport), GO:0006810 (transport), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0016043 (cellular component organization), GO:0051668 (localization within membrane), GO:0045184 (establishment of protein localization), GO:0006839 (mitochondrial transport), GO:0090151 (establishment of protein localization to mitochondrial membrane), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0015031 (protein transport), GO:0072594 (establishment of protein localization to organelle), GO:0071702 (organic substance transport), GO:0008104 (protein localization), GO:0006996 (organelle organization), GO:0090150 (establishment of protein localization to membrane), GO:0061024 (membrane organization), GO:0072657 (protein localization to membrane), GO:0072655 (establishment of protein localization to mitochondrion), GO:0007005 (mitochondrion organization), GO:0033365 (protein localization to organelle), GO:0007006 (mitochondrial membrane organization), GO:0006605 (protein targeting), GO:0051205 (protein insertion into membrane), GO:0051204 (protein insertion into mitochondrial membrane), GO:0006626 (protein targeting to mitochondrion), GO:0070585 (protein localization to mitochondrion), GO:0007007 (inner mitochondrial membrane organization), GO:0045039 (protein insertion into mitochondrial inner membrane)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)