Protein: Vesicle-fusing ATPase (EC 3.6.4.6) (B7Z5J7)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496, ECO:0000256|RuleBase:RU367045}.
Sequence: MQAARCPTDELSLTNCAVVNEKDFQSGQHVIVRTSPNHRYTFTLKTHPSVVPGSIAFSLPQRKWAGLSIGQEIEVSLYTFDKAKQCIGTMTIEIDFLQKKSIDSNPYDTDKMAAEFIQQFNNQALSVGQQLVFSFNEKLFGLLVKDIEAMDPSILKGEPATGKRQKIEVGLVVGNSQVAFEKAENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKASTKVEVDMEKAESLQVTRGDFLASLENDIKPAFGTNQEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDRTPLVSVLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQEMEMLNAFSTTIHVPNIATGEQLLEALELLGNFKDKERTTIAQQVKGKKVWIGIKKLLMLIEMSLQMDPEYRVRKFLALLREEGASPLDFD
InterPro domains: - IPR029067: CDC48 domain 2-like superfamily (homologous_superfamily) [82-195]
- IPR004201: CDC48, domain 2 (domain) [106-178]
- IPR003593: AAA+ ATPase domain (domain) [247-666]
- IPR041569: AAA ATPase, AAA+ lid domain (domain) [418-459]
- IPR039812: Vesicle-fusing ATPase (family) [1-733]
- IPR003959: ATPase, AAA-type, core (domain) [251-663]
- IPR009010: Aspartate decarboxylase-like domain superfamily (homologous_superfamily) [1-80]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [201-728]
- IPR054419: NSF, AAA+ ATPase lid domain (domain) [664-731]
- IPR003338: CDC48, N-terminal subdomain (domain) [1-81]
- IPR003960: ATPase, AAA-type, conserved site (conserved_site) [362-380]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0016887 (ATP hydrolysis activity), GO:0016787 (hydrolase activity), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0005102 (signaling receptor binding), GO:0019904 (protein domain specific binding), GO:0035254 (glutamate receptor binding), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0030165 (PDZ domain binding), GO:0016462 (pyrophosphatase activity), GO:0035255 (ionotropic glutamate receptor binding), GO:0017111 (ribonucleoside triphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0051641 (cellular localization), GO:0023056 (positive regulation of signaling), GO:0048522 (positive regulation of cellular process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0051234 (establishment of localization), GO:0023051 (regulation of signaling), GO:0071840 (cellular component organization or biogenesis), GO:0140352 (export from cell), GO:0033036 (macromolecule localization), GO:0009894 (regulation of catabolic process), GO:0046907 (intracellular transport), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0001919 (regulation of receptor recycling), GO:0006810 (transport), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0070727 (cellular macromolecule localization), GO:0060255 (regulation of macromolecule metabolic process), GO:0051649 (establishment of localization in cell), GO:0032940 (secretion by cell), GO:0031323 (regulation of cellular metabolic process), GO:0016043 (cellular component organization), GO:0080090 (regulation of primary metabolic process), GO:0045184 (establishment of protein localization), GO:0009896 (positive regulation of catabolic process), GO:0001921 (positive regulation of receptor recycling), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0006886 (intracellular protein transport), GO:0006887 (exocytosis), GO:0071705 (nitrogen compound transport), GO:0042176 (regulation of protein catabolic process), GO:0051246 (regulation of protein metabolic process), GO:0010256 (endomembrane system organization), GO:0015031 (protein transport), GO:0051247 (positive regulation of protein metabolic process), GO:0071702 (organic substance transport), GO:0045732 (positive regulation of protein catabolic process), GO:0046903 (secretion), GO:0016192 (vesicle-mediated transport), GO:0008104 (protein localization), GO:0061024 (membrane organization), GO:0007009 (plasma membrane organization), GO:0061025 (membrane fusion), GO:0045026 (plasma membrane fusion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)