Protein: White-opaque regulator 3 (Q5A6T8)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Transcription factor that modulates the white-opaque switch
Subcellular location: Nucleus
Sequence: MDQTYLDQQQLDANVNHQQLSQDTNSIPQQQLQQQQQPLQQLQQYQQQPLSNANFSGDNRFQQYQPRVTPSVSSSQQSIHNTTGYVTMHSGNYTPNQQYGVPNQYTVLQQQPPRQQSYEENINPLSYNSNYRTLSAPIPPLHIQHQLASKQNQDQNQSQNRYEQSSMTSIHTNDNSSSVNNSPNTMMIKQEHSTFQPQHSNEGSSAYHPVDQQNHQQQQQPQQQQQPQQQQQPQQQQQPQQPMTRSICTRCKKGFDQPIIYPKSSNSTNGNNSNGQNSSSIPPPEPRTFKLCDHCRKLQRQRSRRWQKKTKDREGVCRRCGSEIPLAERRFVLCPSCRENLRLRKASRAAQGRCVHCSGPLDASILSKENEGNNNGDEQNNKSNEDQNNESRRGSQEKPARGASHKVCQRCRENDKIRRANLEKMGNCNRCAKALDPNEYGRNKVCFNCRTKKKRSPPENVTNTDEVRTSPIQNQYGMNMSHQYIQPPPPPPPPLMTGHHQFQPQPHMMGHEQMNTFTTMSNSGVAGIQQPNNGMVVGDQQQQQQQHNGSMQLQPTYYQSYVQMPPPLQLQQQQQQQQQHYSLDGIPQQPHSAPTSSFPPPPPPPLQLNQHQGLQQYSHAQQQQQQQHQQQQPYHQEYPNN
InterPro domains: - IPR051647: Mediator complex subunit 12 (family) [190-391]
Interaction partners: - White-opaque regulator 1
- Wor4p
- White-opaque regulator 2
- Adhesion and hyphal regulator 1
- Zinc cluster transcription factor CZF1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0040007 (growth), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0042221 (response to chemical), GO:0048584 (positive regulation of response to stimulus), GO:0019222 (regulation of metabolic process), GO:0045927 (positive regulation of growth), GO:0048522 (positive regulation of cellular process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0009893 (positive regulation of metabolic process), GO:0051716 (cellular response to stimulus), GO:0030447 (filamentous growth), GO:0006950 (response to stress), GO:0007154 (cell communication), GO:0040008 (regulation of growth), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0010570 (regulation of filamentous growth), GO:0060255 (regulation of macromolecule metabolic process), GO:0032101 (regulation of response to external stimulus), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0009891 (positive regulation of biosynthetic process), GO:0009991 (response to extracellular stimulus), GO:0044182 (filamentous growth of a population of unicellular organisms), GO:0104004 (cellular response to environmental stimulus), GO:0042594 (response to starvation), GO:0031325 (positive regulation of cellular metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0071214 (cellular response to abiotic stimulus), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0031668 (cellular response to extracellular stimulus), GO:0009268 (response to pH), GO:0090033 (positive regulation of filamentous growth), GO:0080090 (regulation of primary metabolic process), GO:0036171 (filamentous growth of a population of unicellular organisms in response to chemical stimulus), GO:0071496 (cellular response to external stimulus), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0071310 (cellular response to organic substance), GO:0009267 (cellular response to starvation), GO:0036176 (response to neutral pH), GO:1900428 (regulation of filamentous growth of a population of unicellular organisms), GO:1990928 (response to amino acid starvation), GO:0032104 (regulation of response to extracellular stimulus), GO:0010468 (regulation of gene expression), GO:0071467 (cellular response to pH), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:1900430 (positive regulation of filamentous growth of a population of unicellular organisms), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0036177 (filamentous growth of a population of unicellular organisms in response to pH), GO:0031667 (response to nutrient levels), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0032106 (positive regulation of response to extracellular stimulus), GO:0051252 (regulation of RNA metabolic process), GO:0031669 (cellular response to nutrient levels), GO:1901701 (cellular response to oxygen-containing compound), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0034198 (cellular response to amino acid starvation), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0036178 (filamentous growth of a population of unicellular organisms in response to neutral pH), GO:0032107 (regulation of response to nutrient levels), GO:1900436 (positive regulation of filamentous growth of a population of unicellular organisms in response to starvation), GO:1902680 (positive regulation of RNA biosynthetic process), GO:0046688 (response to copper ion), GO:0006357 (regulation of transcription by RNA polymerase II), GO:0045893 (positive regulation of DNA-templated transcription), GO:0071280 (cellular response to copper ion), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045944 (positive regulation of transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)