Protein: Plectin a (A5WV02)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Cell projection {ECO:0000256|ARBA:ARBA00004316}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Sequence: MAVYKGYRTYSTDSVGSDVVFTEDNLYQGMLRAMDERKDERDRVQKKTFTKWVNKHLVKAQRHITDLYEDLRDGHNLISLLEVLSGETLPREKGRMRFHKLQNVQIALDFLKHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVNGQSDDMTAKEKLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFNAIIHKHRPNLIDINKVYRQTNLENLEQAFSIAERDLGVTRLLDPEDVDVPHPDEKSIITYVSSMYDVMPRVPDVRDGVKANELELRWQEYYELVTMLLQWIRHHVIVFEERKFPSSYEEIEVLWRQFLKFKETELPAKETDKNRSKLIYKSFEGAVQAGQVKVPPNYHPIDVEKEWGRLHVAILEREKLLRSEFERLERLQRIVSKVQMESGVCEEQLNQVETLLQTDIRLLSAGKPIQHASDIETDLNKAENMIRYLFNDVQLLKDGRHLQAEQMYRRVYRLHERLVNLRSEFNLRLKSGVTLSQVPMTQVPMTQISHVQTLQQSPQRVRPDLDEVTLKYIQDLLSWVEENQRRIEGAEWGEDLPSVESQLGSHRGLHQSIEEFKYKIDRARADENQLTPVSKGAYREYLGKLDLQYAKLLTSSKTRLRSLDQLHAFVVAATKELMWLNEKEEEEVNYDWSDRNSNMTAKKDNYSGLMRDLEQREKRVNNVQMTGDKLLKDGHPARKTIEAFTAALQTQWSWILQLCCCIETHLKENTAYFQFFSDVKEAEDRMKKMEDTMKKKYVCDRSITVTRLEDLLQDAVEEKEQLNEFKTHLEGLNRRAKTIIQLKPRNPAQPIKGKLPVQAVCDFKQMEITVHKGDECALVNNSQPYKWKVRDSSGNEAVVPSICFIVPPTNKEAVDVSSGLDGSQQRLMVLWQKLHVDMKSLLSWQYLMRDITLINSWNFIMFKTLRVEEYRLTLKNLEQHYQAFLRDSQDSGLFGADDRMQAENSYNKATQHYDNLLRSVEQGEQDESVCKSYITQIKDLRLRLEGCESRTVNRLRQMVDKEPLKACTQRATEQKKVQTELEGIKKDLDKVVEKSEAVLATSQQSSSAPVLRSEIDITQKKMEHVYGLSSVYLDKLKTIDLVIRSTQGAEDILNKYENQLREVNKVPVNEKEIEASQTQLQKLRSEAEGKQATFDRLEEELQRATEVNKRMSQLHSERDVELEHYRQLVGNLRERWQAVFAQIELRQRELDLLNRQMQAYRESYDWLIRWIADAKQRQDKLHAVPIGGSKGLQEQLTQEKKLLEEIEKNKDKVEDCQKFAKGYIDAIKDYELQLVTYKALVEPIASPLKKAKMESASDDIIQEYVTLRTRYSELMTLSSQYIKFIIETQRRLQDEEKAAEKLKEEERKKMAEMQAELEKQKQLAETHAKAIAKAEQEANELKTKMKDEVSKRQDVAVDSEKQKHNIQRELQELKTLSEQEIKAKSQQVEEALLSRTRIEEEIHIIRLQLETTMKQKNTAETELLQLRAKAVDADKLRNAAQEEAEKLRKQVAEETQKKRKAEEELKRKSEAEKDAAKEKKKALEDLEKFKLQAEEAERHLKQAELEKQRQIQVVEEVAKKTAATQLESKQVALTARLEESLKNEQVMVIQLQEEAEHLKKQQAEADKAREQAEKELETWRQKANEALRLRLQAEEEANKKTAAQEEAEKQKEEAKREAKKRAKAEEAALKQKEAAEMELGNQRKMAEETAKQKLAAEQELIRLRADFEHAEQQRTVLDDELQRLKNDVNSAVKQKKELEEELIKVRKEMEILLQQKSKAEKETMSNTEKSKQLLESEAAKMRELAEEATKLRSVAEEAKKQRQIAEEEAARQRAEAEKILKEKLTAINEATRLKTEAEIALKEKEAENDRLKRKAEEEGYQRKVLEDQAAQHKQAIEEKIGQLKKSSDTELDRQKKIVEETLKQRKVVEEEIHILKLNFEKASSGKQELELELKKLKGIADETQKSKAKAEEEAEKFRKLALEEEKKRKEAEAKVKQIQAAEEEAARQHKAAQEEVGRLMKLAEEAKKQKEIAEKEAEKQVILVQEAAQKCSAAEQKAQNVLVQQNKDSMAQDKLKEEFEKAKKLAQEAEKAKDNAEKEAALLHKKAEEAERQKKAAEAEAAKQAKAQEDAEKLRKEAEKEASRRAEAEAAALKLKQEADSEMAKYKKLAEKTLKQKSSVEEELVKVKVQLDETDKQKSVLDVELKRLKQEVSDAIKQKAQVEDELSKVKIQMEDLLKLKLKIEKENQELMKKDKDNTKKLLEEEAENMKKLAEEAARLNIEAQEAARLRQIAESDLAKQRELAEKMLEEKKQAIQEAAKLKAEAEKLQKQKDQAQVEAQKLLEAKKEMQQRLDQETEGFQKSLEAERKRQLEITAEAEKLKVKVTQLSDAQSKAEEEAKKFKKQADEIKIRLQETEKHTSEKHTVVEKLEVQRLQSKQEADGLHKAIADLEKEKEKLKKEAADLQKQSKEMANVQQEQLQQEKTILQQSFFAEKETLLKKEKAIEEEKKKLEKQFEDEVKKAEALKAEQERQRKLMEEERKKLQSAMDAAIKKQKEAEEEMNGKQKEMQDLEKKRIEQEKLLAEENKNLREKLQQLQSSQKASYTKEIEIQTDKVPEEELVQMTMVETTKKVLNGSTEVDGVKKDVPLAFDGIREKVPASRLHEIGVLSKKEYDKLKKGKTTVQELSKNDKVKMCLKGKDCIGGVIVEPNQKMSIYQALKDKMITQSTAIMLLEAQAASGYIIDPIKNRRLSVSESVKDGLIGPELHTKLLSAERAVTGFKDPFTGDTISVFEAMKKGLITEDQAIKLLDCQYATGGIIDPVNSHHVPVQLACTQGQLDEDLSKILSSPPADKKAFIDPNTKDSLTYSELLDQCKPDAETGIPLLPITEQAAQSERTYSDEETKDVFSKANLTVPFGRFKGKTVTIWEVINSEYFTEDQRKDLIRQYKTGKITVEKIIRIVITVVEDKENKKEPAFDGLRSSVPASELLEAKVINKDLFNKLHNGKATLKDVSELEPVKKALKGTHSIAGVQIESTSEKMSLYDAMKKNLLGTEPALNLLEAQAGTGFIIDPVKNQKLTVDEAVKSGVVGPELHEKLLSAERAVCGYKDPYTGKTVSLFEAMQKDLIKKEQGVRLLEAQLATGGIIDPEKSYRITPDIAYKRGHLNEEMNQNLSKPSDLSTVYVDPNTQEKVTYTELLKRCITDKQTGLPLIPLSEKAIKSKDIEPVSDAQTKENLSHATVELHSGLFKGRVITIWEIINSEYFTEEQRIEFIRQYRSGKITIEKLIKIVISTVDEKEKKRQDNFDGLRGPVPASSLLESKIIDKDTYDKILQGKKKPAEVSGSVKQYLQGSDCIAGVFFQKTKEKLSIYQAMKQKLLTSDTGMSLLEAQAATGYIIDPIRNEMFTVDDAVKAGIVGPEVHEKLLSAEKAVTGYKDPYTGNKISLLQAMQKQLVLREHAIPLLDAQVATGGIIDPVNSHRLPNDVAIERGYFSKQLAKSFKDPTDDIKGFTDPNKDENVTYKQLKERCMTDPEFGVALLPLSKAQTHEEAEKSYVYTEEQAQTDLANTQIDIPHERFAGKQVTLWEVMKSDMLPEEEKQRLLEQYRSGKITKERMVIIIIEIIEQREIIKTEQSMSCDVIRRRVTIDELYRARIIDLETYNLLKQGKKAIREVMEMPSVKQYLFGTGSISGVLSDNYAKVSIYQAMKRGLIKPDIGIDLLEAQAATGFMIDPVKDELLTVDEAVRKGLVGPEFHDKLLSAERAVTGYKDPYSGKVISLFQAMKKDLVPEDYAMKLLEAQVATGGLMDPEYYFRLPIDIAMQRGYMNKETSERISDPSGDVNQFIDPTTDEKVSYASLLKRCKVDKESGLRLLSLADKRLLFKGLRKQITPEELLRSQIIDQKTYTGLMEGTISVEDLSKDLKKYLEGISSIAGVFVEATKDRLSVYQAMKKTMIRPGTAFELLEAQAATGYIIDPIKNLKMNVQEAVKMGVVGPEFKDKLLSAERAVTGYKDPYSGKVISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEMAYKRGLFDEEMNGILTDPSDDTKGFFDPNTEENLTYLQLMERCMTDTETGLSLLLLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYIELAEQECEWEEITTSSSDGVVKSMIIDRRSGRQYDIDDAISKGLIDQSALDQYRAGTLSITEFADMLSGNMSGFRSRSSSFGSSSSYPMSPVPSIKTPATTWTDPTEETGPVAGILDTDTLEKVSVTEAMHRNLVDNITGQRLLEAQACTGGIIDPNTGEKFSVADAQNKGLVDKIMVDRINLAQKAYQGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDVTGRVSLDEAVRKGSLDARTAQKLRDVSGYSKYLTCPKTKLKISYKDAIDRSMIEEGSGLRLLEASSQSSKGLYSPYSISGSGSTSGSRSGSRTGSRSGSRRGSFDATGSGFSMGFSSSYSPTSYGRRYDSGVHGGHQMDELKQALTALASGRNCCYDEKRIFTSSHTQTSLVA
InterPro domains: - IPR036872: CH domain superfamily (homologous_superfamily) [22-267]
- IPR001589: Actinin-type actin-binding domain, conserved site (conserved_site) [45-142]
- IPR043197: Plakin (family) [146-2197]
- IPR041615: Desmoplakin, SH3 domain (domain) [805-871]
- IPR001452: SH3 domain (domain) [816-873]
- IPR018159: Spectrin/alpha-actinin (repeat) [283-1396]
- IPR035915: Plakin repeat superfamily (homologous_superfamily) [2644-4485]
- IPR049538: Plectin-like, spectrin-like repeat (repeat) [391-490]
- IPR041573: Desmoplakin, spectrin-like domain (domain) [906-983]
- IPR001101: Plectin repeat (repeat) [2698-4462]
- IPR001715: Calponin homology domain (domain) [43-264]
Interaction partners: - Nesprin-3
- Actin alpha 1, skeletal muscle b.
- Integrin beta.
- Microtubule actin crosslinking factor 1b.
- SUN domain-containing protein 1
- Dystonin.
- Dystrophin
- Calponin
- Calponin
- Calponin
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007610 (behavior), GO:0009888 (tissue development), GO:0061061 (muscle structure development), GO:0048513 (animal organ development), GO:0007626 (locomotory behavior), GO:0007517 (muscle organ development), GO:0060537 (muscle tissue development), GO:0007519 (skeletal muscle tissue development), GO:0060538 (skeletal muscle organ development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0099513 (polymeric cytoskeletal fiber), GO:0005874 (microtubule), GO:0015630 (microtubule cytoskeleton)