Protein: Dickkopf WNT-signaling pathway inhibitor 1b (Dickkopf-like protein 1) (Dickkopf-related protein 1b isoform X1) (Dickkopf1) (Q9PWH3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Sequence: MMHIAMLSTACLIFMGCIKVAGSTMLNSNAIKVGSGAAGASHPVSPSPDVSLLDSLNFALDTPQPLICESDEECGGEEFCFQSRGVCLQCKKRRKRCIRDAMCCPGNHCSNGVCIPNDPDMIQQLGMEEFVSIAHENSTALMPKVSTQGSPQNQMLKGLEGENCLRSSDCAEGLCCARHFWSKICKPVLKEGQVCTKHKRKGTHGLEIFQRCDCGEGLSCRTQRGDGGKASRSLHTCQRH
InterPro domains: - IPR048500: Dickkopf-related protein 1/2/4, C-terminal subdomain 1 (domain) [160-189]
- IPR039863: Dickkopf related protein 1-4 (family) [62-240]
- IPR048499: Dickkopf-related protein 1/2/4, C-terminal subdomain 2 (domain) [192-240]
- IPR047304: Dickkopf-related protein 1, second cysteine-rich domain (domain) [157-238]
- IPR006796: Dickkopf, N-terminal cysteine-rich (domain) [68-115]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0040007 (growth), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0048869 (cellular developmental process), GO:0048589 (developmental growth), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0023057 (negative regulation of signaling), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0043696 (dedifferentiation), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0040012 (regulation of locomotion), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:2000145 (regulation of cell motility), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009966 (regulation of signal transduction), GO:0003170 (heart valve development), GO:0035295 (tube development), GO:0048598 (embryonic morphogenesis), GO:0009888 (tissue development), GO:0060322 (head development), GO:0010646 (regulation of cell communication), GO:0030900 (forebrain development), GO:0009790 (embryo development), GO:0042246 (tissue regeneration), GO:0043697 (cell dedifferentiation), GO:0016477 (cell migration), GO:0031099 (regeneration), GO:0048882 (lateral line development), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0048732 (gland development), GO:0007369 (gastrulation), GO:0030111 (regulation of Wnt signaling pathway), GO:0060485 (mesenchyme development), GO:0030334 (regulation of cell migration), GO:0061008 (hepaticobiliary system development), GO:0001667 (ameboidal-type cell migration), GO:0007420 (brain development), GO:0022008 (neurogenesis), GO:0021872 (forebrain generation of neurons), GO:0048568 (embryonic organ development), GO:0007399 (nervous system development), GO:0061009 (common bile duct development), GO:0072359 (circulatory system development), GO:0007417 (central nervous system development), GO:0030178 (negative regulation of Wnt signaling pathway), GO:0007398 (ectoderm development), GO:0060429 (epithelium development), GO:0030182 (neuron differentiation), GO:0007507 (heart development), GO:1990399 (epithelium regeneration), GO:0048925 (lateral line system development), GO:0042074 (cell migration involved in gastrulation), GO:0030903 (notochord development), GO:0021953 (central nervous system neuron differentiation), GO:0003197 (endocardial cushion development), GO:0048884 (neuromast development), GO:0001889 (liver development), GO:0048699 (generation of neurons), GO:0090090 (negative regulation of canonical Wnt signaling pathway), GO:0048916 (posterior lateral line development), GO:0060828 (regulation of canonical Wnt signaling pathway), GO:0021879 (forebrain neuron differentiation), GO:0048881 (mechanosensory lateral line system development), GO:0048915 (posterior lateral line system development), GO:0048919 (posterior lateral line neuromast development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure), GO:0005576 (extracellular region)