Protein: ATP-dependent RNA helicase (EC 3.6.4.13) (C6KTE4)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Not known
Sequence: MMDDDNDYNTMKNSNDNNLKKTKKNSIIKKKKKKKKKEILENKDSNIDNLKNENYRSESEAESESTNDSVSLNNIEEDNELNENSENNENNENDEDNKNNKNNENNENTSSEEICDHDKNDKTYTDEIKSNNSDHNNNNSKEHFYSELKFEELNICDALKKGLKELNFVTLTEIQAKCIPHFLSGKDILGAAKTGSGKTLAFLVPSINILYNIKFLPKNGTGVLIISPTRELCLQIYQVCKDLCKYIPQTNGIIIGGMSRNEEKKKFIHGINILIATPGRLLDHMQNTKEFIYKNLICLIIDEADRLLQIGFEEEINLIIKRLPKKRQTALFSATQTTKVESLIRLSLQKPIFIEVTTKIATVERLQQGYALVDEDKRFLLLFTFLKKNMSKKIMVFFNNCMSVQFYNDLLNYIDIPTYCIHGKKKQNKRLKSFHDFSAAKCAILLCTNVAARGLDIPNVNYIIQYDPPDDSKEYIHRVGRTCRGQDSNGSAIIFLMKHELKFLNYLKFYNIPINQFAYDPNKLINIQSHIQSIVTKNFHLHKMAREAFKSYLNGYITYALKDVFDVNNLNLLLTSKNFGLEVPPKVDLNLKLNVKKKKFK
InterPro domains: - IPR044773: DDX18/Has1, DEAD-box helicase domain (domain) [160-354]
- IPR000629: ATP-dependent RNA helicase DEAD-box, conserved site (conserved_site) [300-308]
- IPR014014: RNA helicase, DEAD-box type, Q motif (domain) [148-176]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [76-595]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [167-369]
- IPR011545: DEAD/DEAH-box helicase domain (domain) [172-341]
- IPR001650: Helicase, C-terminal domain-like (domain) [365-525]
- IPR025313: ATP-dependent rRNA helicase SPB4-like, C-terminal extension (domain) [526-589]
Interaction partners: - Ribosome biogenesis protein BOP1 homolog
- Ribosome biogenesis protein YTM1, putative
- Nucleolar complex protein 2, putative
- Ribosomal protein L1, putative
- Pescadillo homolog
- Putative rRNA methyltransferase
- Ribosome biogenesis protein BRX1, putative
- 60S ribosome subunit biogenesis protein NIP7 homolog
- Ribosome biogenesis protein MRT4, putative
- Ribosome biogenesis protein NSA2 homolog
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0097159 (organic cyclic compound binding), GO:0004386 (helicase activity), GO:0008186 (ATP-dependent activity, acting on RNA), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0140098 (catalytic activity, acting on RNA), GO:0042802 (identical protein binding), GO:0003724 (RNA helicase activity), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0051276 (chromosome organization), GO:0071103 (DNA conformation change), GO:0032392 (DNA geometric change), GO:0032508 (DNA duplex unwinding)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)