Protein: Nuclear factor of activated T-cells, cytoplasmic 1 (W5U9R6)
Organism: Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MPAPACTRPDSSANFTRPALGKRRGPELCCSAQFSMKSAEEEAFSYTPNVSLSLPLGMANPCLASQYHSLQSSPVISVSSCHQASYGLHESAMAPNYYFPGLRPNGAPPLERPRIEITTYGQMPEEEVEESGTMGPVAKRVNIVTLTLPSADGYRDPSSLSPASSCNSEASYESGFYNYENSPQNSPWQSPCVSPKGTSISMLSCPPHGHAPGPSPRHSPSTSPNDDIGSHGKRKYSFNGTPYGHASGISPNHSPGASPQGSPRLEENWLGTTNQYTNSAIVAAINALSTDGLPDLGDGVPNKSRKTSVEHNSSMSLKVEPANDDLGTDLGQEDYTNSNRMPFKKESYCSGFLDVPPHPYSWPKPKPYLSPSLPALDWQLPSCSGPYNLQIEVQPKSHHRAHYETEGSRGAVKAPSGGHPVVQLYGYMESEPLTLQLFIGTADDRLLRPHAFYQVHRITGKTVSTASHEAMQSNTKVLEIPLLPENNMRAIIDCAGILKLRNSDIELRKGETDIGRKNTRVRMVFRVHINQPNGRTVSLQAASNPIECSQRSAQELPMVDKQSLDSYPASGGKRMLLSGHNFLPESKVMFVEKAQDGHHVWETEANVDKDSRKSTSLVVEIPPYRNQRISSAVPVSFYVCNGKRKRSQYQRFTYLPCNVPMIKTEPADDYESRMSIHANPYFGQQRLPTMMPLDDPEPCMVASYAPCASRPTPMLCSSPSSSPKLHDLSPVPFPKCLSNSPTHSTMPGGMASMQDPPTHHGLALPSSPDPTSLAMHHPQGSPHLGSPSYHPLYPNSSPSSSPNSHPSTPGAATESPYLATFGSTQPGGSSPTLLADDHASPVLPVTIKQEPQELDQMYLDDVNEIIRNDLSCTSAHGHS
InterPro domains: - IPR002909: IPT domain (domain) [556-655]
- IPR008366: Nuclear factor of activated T cells (NFAT) (family) [38-875]
- IPR037059: Rel homology domain (RHD), DNA-binding domain superfamily (homologous_superfamily) [375-550]
- IPR032397: Rel homology dimerisation domain (domain) [559-656]
- IPR008967: p53-like transcription factor, DNA-binding domain superfamily (homologous_superfamily) [378-554]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [551-654]
- IPR014756: Immunoglobulin E-set (homologous_superfamily) [556-656]
- IPR011539: Rel homology domain, DNA-binding domain (domain) [371-553]
Interaction partners: - Calcineurin subunit B type 1
- Serine/threonine-protein phosphatase.
- Serine/threonine-protein phosphatase
- Serine/threonine-protein phosphatase
- Serine/threonine-protein phosphatase
- Serine/threonine-protein phosphatase
- Stress-activated protein kinase JNK
- Stress-activated protein kinase JNK
- Stress-activated protein kinase JNK
- Mitogen-activated protein kinase.
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding), GO:0000987 (cis-regulatory region sequence-specific DNA binding), GO:0000977 (RNA polymerase II transcription regulatory region sequence-specific DNA binding), GO:0000978 (RNA polymerase II cis-regulatory region sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009719 (response to endogenous stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0048545 (response to steroid hormone), GO:0033993 (response to lipid), GO:0014070 (response to organic cyclic compound)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)