Protein: Exocyst complex component 6 (Exocyst complex component Sec15) (Q18286)
Organism: Caenorhabditis elegans
Function: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence: MPNSSSTSQPATTGSETASTSYVNYVEMSAEQEYFLYELETTDSGSMGLVLRAIYDTGDVQSFARALQQRISHYDKNIQKVCSFHYQSFVDAMQELMKLKEQCQDIKEETVAIDAEIQQISQRLCQKKQEIVRYRKLMKNAKTAMDQIAVCLPVLENYAKLQEQMSNRKYYQALKTLEELEHTHLALVEKYRFTQVLAKSMAPVRLEIKEKAYSEFKDFLENIKKVAGRIGKHASKDTAEQHSFGVTDAERAKKIQEEARKNASNVEIEVSADGSIVKKNMSPKRNMKMQVEDDEQVSAQDLIDFTPVHRCCQIFNVLGAKEEFEQYYRQQRKEQCDLVIEPTHKMNNFKHYVEYLDEIVGFFVVEDQILMTQSNLSTTVDKDKLWDNALMKIRQHLDARFGGSPDVLMMLKMKKVILLFILTMKSYGYAVAPLYELLQNFRDQYNEILVKEYCAQFERDLEKDNYTPITVNSEEEFRTIIRKFPFYKRSMEQEPFPRRFPFSPFVTDAYTQAKNYLIGCLKFMDNLQLNTSAVDDTVRRCANVLLGRWAGVLKSFVHKRLSMIQLVQITINLGYLEKSCESLGAFITSKTSGEEAIGTTSHQVVLSEKVFRDVRSEVEQQIDECMRSKVDEIIDLANYDWELPAAAGQASEFISDLINFLQTTFTSFTNLPSGLAKHVCTQTCKHISQSMSDFLLSPETKCISTGALDQFSLDVMQCEMFTTRCPVAGVDPQTLSMTFADLRQLLDLVMSSDWTTFNAEYGKDHAKYLRVKASTAIVVLEKMIEFERKSTGFFGIAKGDRKKLLDTIVRQLKLLEI
InterPro domains: - IPR042044: EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 (homologous_superfamily) [614-756]
- IPR046361: Exocyst complex subunit EXOC6/Sec15, C-terminal (domain) [433-782]
- IPR007225: Exocyst complex component EXOC6/Sec15 (family) [8-817]
- IPR042045: Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 (homologous_superfamily) [430-606]
- IPR048359: Exocyst complex component EXOC6/Sec15, N-terminal domain (domain) [67-234]
Interaction partners: - Exocyst complex component 1
- Exocyst complex component 5
- Exocyst complex component 4
- Exocyst complex component 2
- Exocyst complex component 7
- Exocyst complex component 3
- Exocyst component Exo84 C-terminal domain-containing protein
- Rab8
- GDP/GTP exchange factor Sec2 N-terminal domain-containing protein
- RNA polymerase II-associated protein 3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0051179 (localization), GO:0022414 (reproductive process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0051641 (cellular localization), GO:0009628 (response to abiotic stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0042221 (response to chemical), GO:0042330 (taxis), GO:0140029 (exocytic process), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0033036 (macromolecule localization), GO:0051640 (organelle localization), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0006903 (vesicle targeting), GO:0140352 (export from cell), GO:0048609 (multicellular organismal reproductive process), GO:0032989 (cellular component morphogenesis), GO:0007276 (gamete generation), GO:0007281 (germ cell development), GO:0090522 (vesicle tethering involved in exocytosis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0099022 (vesicle tethering), GO:0051649 (establishment of localization in cell), GO:0051648 (vesicle localization), GO:0051668 (localization within membrane), GO:0009453 (energy taxis), GO:0000902 (cell morphogenesis), GO:0046907 (intracellular transport), GO:0051656 (establishment of organelle localization), GO:0006810 (transport), GO:0099022 (vesicle tethering), GO:0070727 (cellular macromolecule localization), GO:0032940 (secretion by cell), GO:0016043 (cellular component organization), GO:0006935 (chemotaxis), GO:0007297 (follicle cell of egg chamber migration), GO:0016477 (cell migration), GO:0030030 (cell projection organization), GO:0097479 (synaptic vesicle localization), GO:0097485 (neuron projection guidance), GO:0032990 (cell part morphogenesis), GO:0007423 (sensory organ development), GO:0048477 (oogenesis), GO:0046903 (secretion), GO:0051650 (establishment of vesicle localization), GO:0048666 (neuron development), GO:0022008 (neurogenesis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0006887 (exocytosis), GO:0007399 (nervous system development), GO:0016197 (endosomal transport), GO:0007292 (female gamete generation), GO:0015031 (protein transport), GO:0016192 (vesicle-mediated transport), GO:0008104 (protein localization), GO:0048858 (cell projection morphogenesis), GO:0030182 (neuron differentiation), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:1990778 (protein localization to cell periphery), GO:0007411 (axon guidance), GO:0031175 (neuron projection development), GO:0072659 (protein localization to plasma membrane), GO:0048699 (generation of neurons), GO:0032456 (endocytic recycling), GO:0048812 (neuron projection morphogenesis), GO:0061564 (axon development), GO:0007409 (axonogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0043204 (perikaryon), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0150034 (distal axon), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0044297 (cell body), GO:0099023 (vesicle tethering complex), GO:0030427 (site of polarized growth), GO:0098793 (presynapse), GO:0036477 (somatodendritic compartment), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0030054 (cell junction), GO:0043025 (neuronal cell body), GO:0000145 (exocyst), GO:0120025 (plasma membrane bounded cell projection), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0045202 (synapse), GO:0005938 (cell cortex), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0055037 (recycling endosome), GO:0043005 (neuron projection), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0030424 (axon), GO:0097708 (intracellular vesicle)