Protein: Loquacious, isoform F (X2J5X6)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MDQENFHGSSLPQQLQNLHIQPQQASPNPVQTGFAPRRHYNNLVGLGNGNAVSGSPVKGAPLGQRHVKLKKEKISAQVAQLSQPGQLQLSDVGDPALAGGSGLQGGVGLMGVILPSDEALKFVSETDANGLAMKTPVSILQELLSRRGITPGYELVQIEGAIHEPTFRFRVSFKDKDTPFTAMGAGRSKKEAKHAAARALIDKLIGAQLPESPSSSAGPSVTGLTVAGSGGDGNANATGGGDASDKTVGNPIGWLQEMCMQRRWPPPSYETETEVGLPHERLFTIACSILNYREMGKGKSKKIAKRLAAHRMWMRLQETPIDSGKISDSICGELEGEPRSSENYYGELKDISVPTLTTQHSNKVSQFHKTLKNATGKKLLKLQTCLKNNKIDYIKLLGEIATENQFEVTYVDIEEKTFSGQFQCLVQLSTLPVGVCHGSGPTAADAQRHAAQNALEYLKIMTKK
InterPro domains: - IPR051247: RISC Loading Complex Component (family) [124-460]
- IPR014720: Double-stranded RNA-binding domain (domain) [135-460]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0043021 (ribonucleoprotein complex binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0051301 (cell division), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0009892 (negative regulation of metabolic process), GO:0044237 (cellular metabolic process), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0050794 (regulation of cellular process), GO:0098727 (maintenance of cell number), GO:0019827 (stem cell population maintenance), GO:0048609 (multicellular organismal reproductive process), GO:0044238 (primary metabolic process), GO:0007276 (gamete generation), GO:0007281 (germ cell development), GO:0044085 (cellular component biogenesis), GO:0030718 (germ-line stem cell population maintenance), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0046483 (heterocycle metabolic process), GO:0048731 (system development), GO:0060255 (regulation of macromolecule metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0042078 (germ-line stem cell division), GO:0043170 (macromolecule metabolic process), GO:0008356 (asymmetric cell division), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0016043 (cellular component organization), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0017145 (stem cell division), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0048477 (oogenesis), GO:0006325 (chromatin organization), GO:0010468 (regulation of gene expression), GO:0022607 (cellular component assembly), GO:0007399 (nervous system development), GO:0007292 (female gamete generation), GO:0090304 (nucleic acid metabolic process), GO:0098728 (germline stem cell asymmetric division), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0007417 (central nervous system development), GO:0043933 (protein-containing complex organization), GO:0051252 (regulation of RNA metabolic process), GO:0098722 (asymmetric stem cell division), GO:0010467 (gene expression), GO:0010629 (negative regulation of gene expression), GO:0016070 (RNA metabolic process), GO:0060966 (regulation of gene silencing by RNA), GO:0070920 (regulation of production of small RNA involved in gene silencing by RNA), GO:0065003 (protein-containing complex assembly), GO:0048132 (female germ-line stem cell asymmetric division), GO:0031047 (RNA-mediated gene silencing), GO:0006396 (RNA processing), GO:0040029 (epigenetic regulation of gene expression), GO:0022618 (ribonucleoprotein complex assembly), GO:0071826 (ribonucleoprotein complex subunit organization), GO:0034470 (ncRNA processing), GO:0070918 (regulatory ncRNA processing), GO:0070922 (RISC complex assembly), GO:0007549 (dosage compensation), GO:0034660 (ncRNA metabolic process), GO:0035196 (miRNA processing), GO:0010586 (miRNA metabolic process), GO:0009047 (dosage compensation by hyperactivation of X chromosome), GO:0030422 (siRNA processing), GO:0031054 (pre-miRNA processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0140535 (intracellular protein-containing complex), GO:1905348 (endonuclease complex), GO:1902555 (endoribonuclease complex)