wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Uncharacterized protein LOC497366 precursor (Q7T2V7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MDLLLSVFLLLCSIHQTFTSVLGRNTRNLFTERVCCKRQSHVIYIGKDISGSPVNVDVGVCRTHCGQSAHFVALEAGLRASKYSSMLDFLRHKKIRHLDPSSSSSSEVIIGSPSCGLSSSCEPAGVRVDPVMLYEGLREIEIIQDCHCEAKISQCVRAPALKTYHSNTPYETVIDVGKCVGSKGAPEGFSCVPTKFDSTFIETPNKVELIQTVAQCKLIKGCYRMPLMEYHYETTYSDDGVQIESLKEIDVGRCLGSCTSGSRCLLRSVSDLGECLLWAEGQGKACVPQSFESHTILTQNGQIYTVDAITSCVCQS
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0022008 (neurogenesis), GO:0021782 (glial cell development), GO:0010001 (glial cell differentiation), GO:0007417 (central nervous system development), GO:0007399 (nervous system development), GO:0048709 (oligodendrocyte differentiation), GO:0042063 (gliogenesis), GO:0014003 (oligodendrocyte development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: lysozyme (Q90YS5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MRLAVVFLCLAWMSSCESKTLGRCDVYKIFKNEGLDGFEGFSIGNYVCTAYWESRFKTHRVRSADTGKDYGIFQINSFKWCDDGTPGGKNLCKVACSDLLNDDLKASVGCAKLIVKMDGLKSWETWDSYCNGRKMSRWVKGCEQRKQSLRA
InterPro domains: - IPR023346: Lysozyme-like domain superfamily (homologous_superfamily) [19-143]
- IPR000974: Glycoside hydrolase, family 22, lysozyme (family) [20-141]
- IPR019799: Glycoside hydrolase family 22 domain (domain) [92-110]
- IPR001916: Glycoside hydrolase, family 22 (family) [3-145]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0008194 (UDP-glycosyltransferase activity), GO:0035250 (UDP-galactosyltransferase activity), GO:0008378 (galactosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0006950 (response to stress), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006952 (defense response), GO:0043207 (response to external biotic stimulus), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0042742 (defense response to bacterium), GO:0050829 (defense response to Gram-negative bacterium), GO:0050830 (defense response to Gram-positive bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0043227 (membrane-bounded organelle), GO:0120025 (plasma membrane bounded cell projection), GO:0005929 (cilium), GO:0031514 (motile cilium)
Protein: Myocilin (Q5F0G5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell projection, cilium. Cytoplasmic vesicle. Golgi apparatus. Mitochondrion inner membrane. Mitochondrion intermembrane space. Mitochondrion outer membrane. Rough endoplasmic reticulum. Secreted, extracellular exosome. Secreted, extracellular space, extracellular matrix
Sequence: MWFLAVLWISSLLMGSQVQSSANLRRANAGNGRCQYTFMVDSPTEASCPSPGSTPEMEALMSRLGLLEALVARLVGGEAMPESSQSSGSGLQDSYNQVMGENAQLKREKQRLDRQVQDLQQRMEELRQEAERLRSRPCMQQTSSRVPQKDNSFRPGSGHVPSNLASRPGNPQEDKSSLRDPAWQYSNPGYQELTAVVTEVTAPNQDGPADISGCGDLVWVENPEVHRKADSIAGKYGVWMQDPEAKEPYGPDMVWRIDSVGSEVRQLFGYENMDQLTRGFPTKVLLLPESVESTGATMYKGSLYYQRRLSRTLIRYDLHAESIAARRDLPHAGFHGQFPYSWGGYTDIDLAIDENGLWAIYSTNKAKGAIVISQLDPHNLEVKGTWETKIRKTSVANAFMICGKLYTVASYTSPNTTVNYMFDTATSQGKAISVPFKNRYRYNSMVDYNSAKRKLYAWDNYYMVSYSVRLGKQE
InterPro domains: - IPR050605: Olfactomedin-like domain-containing protein (family) [26-469]
- IPR003112: Olfactomedin-like domain (domain) [213-472]
Interaction partners: - WD repeat domain 36
- Cytochrome P450 1A
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0001968 (fibronectin binding), GO:0005102 (signaling receptor binding), GO:0008092 (cytoskeletal protein binding), GO:0017022 (myosin binding), GO:0001664 (G protein-coupled receptor binding), GO:0005109 (frizzled binding), GO:0032027 (myosin light chain binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0072001 (renal system development), GO:0001822 (kidney development), GO:0048793 (pronephros development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0099080 (supramolecular complex), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0035770 (ribonucleoprotein granule), GO:0036464 (cytoplasmic ribonucleoprotein granule), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0099081 (supramolecular polymer), GO:0043231 (intracellular membrane-bounded organelle), GO:0099512 (supramolecular fiber)
Protein: G-protein coupled receptor 6 (A0A0G2L0R2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane; Multi-pass membrane protein
Sequence: MNESESLTNESAMGFPSSSWLEAETFASNGTLALSSASPNFHVNPWDIMLCLSGTVIACENAIVVAIIFYTPTLRNPMFVLIGSLATADLLAGMGLILNFAFQYLVSSETISLITVGFLVASFTASISSLLAITVDRYLSLYNALTYFSEKTLHYVHLMLVGTWGASLCLGLLPVLGWNCLDDASTCSIVRPLKRSNLTLLATSFFIIFILMLSLYFKICKIVCRHAHQIALQQHFFTTSHYVATKKGVSTLAIILGTFGASWLPFAIYCLVGEREYPPVYTYATLLPATYNSMINPIIYAYRNTEIQRSIHMLFCGCFQSNGSYRSRSPSEV
InterPro domains: - IPR001151: G protein-coupled receptor 6 (family) [149-323]
- IPR017452: GPCR, rhodopsin-like, 7TM (domain) [60-300]
- IPR000723: G protein-coupled receptor 3/6/12 orphan (family) [45-312]
- IPR000276: G protein-coupled receptor, rhodopsin-like (family) [60-315]
Interaction partners: - Nuclear receptor-binding protein 2
- Forkhead box O4
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004930 (G protein-coupled receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0042592 (homeostatic process), GO:0051716 (cellular response to stimulus), GO:0048878 (chemical homeostasis), GO:0019725 (cellular homeostasis), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0050801 (monoatomic ion homeostasis), GO:0055082 (intracellular chemical homeostasis), GO:0098771 (inorganic ion homeostasis), GO:0007186 (G protein-coupled receptor signaling pathway), GO:0055080 (monoatomic cation homeostasis), GO:0006873 (intracellular monoatomic ion homeostasis), GO:0055074 (calcium ion homeostasis), GO:0030003 (intracellular monoatomic cation homeostasis), GO:0006874 (intracellular calcium ion homeostasis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: WD repeat-containing protein WRAP73 (B8A4V4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MNFSEVFKQSNQLCKVSPDGKYLATCVQYRLVVRDIGTLQIVHLYTCLDQVMHMEWSSDSLFILCAMYKRGLVQVWSLEQPDWHCKIDEGSIGLVSSRWSPDGRHILNTTEFNLRITVWSLCTKSVSYIKYPKACQKGMDFTADGRYMALAERRDCKDYISVFVCDDWHLLRHFESETQDLAGLEWSPNGCVLAVWDNCLEYKILLYSLDGRLLSFYSAYEWSLGIKSVAWSPSSQFLAIGSYDEKVRILNHITWKKITEFEHPATITNSKAVVFKEVEKRPVVSEDLSIRQLTVDNALFSTQSKYEITQLPVQVPVVKPDPERANPKIGISAVAFSADNRYLATKNDNMPQSLWVWDMQKFSLLAVLEQTAPVRCFVWDPHLPRLALCTGNTKLYMWSPAGCISVTVPVEGFQVQSLFWHCTGSSLVLLSKDQLCLCYTDAEEQK
InterPro domains: - IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [7-445]
- IPR001680: WD40 repeat (repeat) [38-399]
- IPR052778: Centrosome-associated WD domain-containing protein (family) [1-443]
Interaction partners: - ATP-dependent RNA helicase DDX51
- Tumor protein p63-regulated 1-like
- peptidylprolyl isomerase
- NEDD1 gamma-tubulin ring complex targeting factor
- Double-strand-break repair protein rad21-like protein 1
- Rho guanine nucleotide exchange factor (GEF) 16
- Peptidyl-prolyl cis-trans isomerase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0048731 (system development), GO:0030030 (cell projection organization), GO:0006996 (organelle organization), GO:0007399 (nervous system development), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0044782 (cilium organization), GO:0060271 (cilium assembly), GO:0120031 (plasma membrane bounded cell projection assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Solute carrier family 15 member 1 (Q7SYE4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Electrogenic proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides. Transports neutral and monovalently charged peptides with a proton to peptide stoichiometry of 1:1 or 2:1. Primarily responsible for the absorption of dietary di- and tripeptides from the small intestinal lumen. Mediates transepithelial transport of muramyl and N- formylated bacterial dipeptides contributing to recognition of pathogenic bacteria by the mucosal immune system
Subcellular location: Apical cell membrane. Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein
Sequence: MADKEGHKQKKERASCFGYPVSIFFIVVNEFCERFSYYGMKAVLVLYFKYFIGWDDDLSTTIYHTFVALCYLTPIMGAIIADSWLGKFKTIVYLSIVYTIGQVIMAISAIHDITDANRDGKPDNKTLHISLSMLGLILIALGTGGIKPCVAAFGGDQFEDHQEKQRSTFFSIFYLSINAGSLLSTLITPILRSQECGIYAKQSCYPLAFGVPAALMVVALIVFVIGHKMYIMESPKGNILLQVINCIGFALNNRFRHRGKQYPKREHWMDWAEEKYDKLLIAQVKMVVKVLFLYIPLPMFWALFDQQGSRWTIQATTMDGNFGGFVIQPDQMQIVNPILIVIMVPIMDSAIYPLIKLCRINFTPLRKMTVGMVLAALAFVAAALLQLQIDETMPKFPSTSQTQLKFLNVESTSLPVVVEGQDQFMVPGFNASSEYLTLDKENVTISAGGVNDTAFLKTGTRHTVLMNAAGMRNTLDDLTEKPEQGLNAIRFVNGWENRLNVSVKSDNVHADPLDASVYLLVPHGKVNFTIFDGGDGKCHYIMQLGFGSTYTVLIPSTFAFGQTCSESFEAVQDMEPNRIHMAWQVIQYFLLTCGEVVYSVTGLDFSYSQAPSNMKSVLQAGWLLTVAVGNIIVLIVAEAGSLPDQWAEYLLFASLLVAVSIIFAIMAYFYTYIDPNEIEAKFKELEPEDKKRKEMQMTAKDNMAYVHNENTNIKQTKI
InterPro domains: - IPR000109: Proton-dependent oligopeptide transporter family (family) [88-637]
- IPR036259: MFS transporter superfamily (homologous_superfamily) [1-685]
- IPR018456: PTR2 family proton/oligopeptide symporter, conserved site (conserved_site) [77-182]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity), GO:0005342 (organic acid transmembrane transporter activity), GO:0046943 (carboxylic acid transmembrane transporter activity), GO:0015171 (amino acid transmembrane transporter activity), GO:0015175 (neutral L-amino acid transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0009620 (response to fungus), GO:0043207 (response to external biotic stimulus), GO:0001878 (response to yeast)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)
Protein: Transportin-1 (A0A8N7TD97)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm. Nucleus
Sequence: MECQWKPDEQGLQQILQLLKESQSPDTSTQRSVQQKLEQLNQYPDFNNYLIFVLTKLKTEDEPTRSLSGLILKNNVKAHYQNFPNGVSDFIKNECLQSIGDSSPLIRATVGILITTIASKGELQNWPELLPKLCLLLDSEDYNTCEGAFGALQKICEDSAEILDSDMLERPLNVMIPKFLQFFKHSSPKIRSHAIACVNQFIISRTQALMLHIDPFIENLFALAGDEEPEVRKNVCRALVMLLEVRLDRLLPHMHNIIEYMLQRTQDQDENVALEACEFWLTLAEQPVCKEVLCGHLPKLTPVLVNGMKYSEIDIILLKGDVEEDEAIPDNEQDIRPRFHRSRTVAQQHEGGDSIEEDDDDEDDLDDDETISDWNLRKCSAAALDVLANVFRDDLLLHILPLLKELLFHPEWLIKESGILVLGAIAEGCMQGMIPYLPELIPHLVLCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPLIQKWNQLKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVNLVQKTLAQAVLHQNQPEYYEAPDKDFMIVALDLLSGLAEGLGGNIEQLVARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKASFQHVKPCIANFMPILGTNLNPELISVCNNATWAIGEISIQMGSEMQPYVPLVLQQLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMITVNPGGVVQDFIFFCDAVASWMNPKDDLREMFYKILHGFKNQVGDENWRRFSDQFPPPLKERLAAFYGV
InterPro domains: - IPR058584: Importin subunit beta-1/Transportin-1-like, TPR repeats (domain) [667-769]
- IPR016024: Armadillo-type fold (homologous_superfamily) [1-881]
- IPR011989: Armadillo-like helical (homologous_superfamily) [1-891]
- IPR000357: HEAT repeat (repeat) [217-245]
- IPR001494: Importin-beta, N-terminal domain (domain) [33-101]
- IPR040122: Importin beta family (family) [11-866]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0001775 (cell activation), GO:0045321 (leukocyte activation), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0046649 (lymphocyte activation), GO:0030097 (hemopoiesis), GO:0042110 (T cell activation), GO:0002521 (leukocyte differentiation), GO:0030098 (lymphocyte differentiation), GO:1903131 (mononuclear cell differentiation), GO:0030217 (T cell differentiation), GO:0033077 (T cell differentiation in thymus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Synaptosomal-associated protein 29 (A0A8M1NZG6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Also plays a role in ciliogenesis by regulating membrane fusions
Subcellular location: Cell projection, cilium membrane; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein
Sequence: MSAYPKSHNPFADDDEEEDSRAAPRRGFNFDDDPEESSLSPAERRQRQLQQEVMRTAQSAVDSSHRSLGLIYESEKVGAETAEELIRQGEALKRTERMIDNMEQDMRTSQRHINTIKSVWGGMVNYFKGKPEPPKPAQKDQPVCYEASSRLQTALAESKQQEDKYQASHPNLRKLETSGFGASAALDNGSSDQNGFPKNKQLRAAHQQLDRNLDEMSLGLGRLKNLGLGLQTEIDEQDISLDALLNKADTMDGKISSTNRQLKSLK
InterPro domains: - IPR000727: Target SNARE coiled-coil homology domain (domain) [49-265]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0071840 (cellular component organization or biogenesis), GO:0032989 (cellular component morphogenesis), GO:0000902 (cell morphogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0016043 (cellular component organization), GO:0022008 (neurogenesis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0032990 (cell part morphogenesis), GO:0048858 (cell projection morphogenesis), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0048812 (neuron projection morphogenesis), GO:0061564 (axon development), GO:0007409 (axonogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0055037 (recycling endosome), GO:0031982 (vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle)
Protein: G protein-coupled receptor 185 a (A0A2R9YJM5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane; Multi-pass membrane protein
Sequence: MNDLLQNSSLLNWDVLEERNASLAPPWEVEPVPVFINPWDVLLCVTGTLMSCENAVVIALIAYTPTLRAPMFVLIGSLAFADLLAGLGLILNFIITYIIDSGLVTLLSAGLLITAFSASVLNILAITVDRYLSLYNALTYHTERTMTFTYVTLIFMWIISAALGSLPVLGWNCLEDESTCSICRPVNKNNAAALAVSFLLVFALILQLYLQICKIAFRHAQQIAVQRQFMTASHASSTTKGVSTLTTILGTFAFCWIPLAMYSLVADTRSPVIYTYVTALPAICHSIINPMVYAFRNPEILRSLRIACCGCMPYSFSVRPRTPSDV
InterPro domains: - IPR017452: GPCR, rhodopsin-like, 7TM (domain) [53-293]
- IPR000723: G protein-coupled receptor 3/6/12 orphan (family) [38-305]
- IPR000276: G protein-coupled receptor, rhodopsin-like (family) [53-301]
Interaction partners: - Interferon-induced very large GTPase 1
- Plac8 onzin-related protein 4
- Plac8 onzin-related protein 3
- Calcium-activated chloride channel regulator 1 isoform X2
- LIF receptor subunit alpha b
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004930 (G protein-coupled receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007186 (G protein-coupled receptor signaling pathway), GO:0007188 (adenylate cyclase-modulating G protein-coupled receptor signaling pathway), GO:0007189 (adenylate cyclase-activating G protein-coupled receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Zinc finger MIZ domain-containing protein 2 isoform X1 (A0A8M2B1Q3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
Sequence: MNPINSMKPALPPTPHSDSSYPYDPVPWQQGPSQPAGSLSVVTTVWGVTNPSASQVFGAPMGPGGNSAGGHMMPGSSPGMNSPQFMSQQGYPEPNKTYMQQGMYGRPSGGYPAGPGYGGSYPNNGAGSLGMPPHGVRPPTDFTQAAAAAAVAAAAATATATATATVAALQEKQNQELSYGPMGGASSYNTQFLSHSGPRGPPGMSPSGMVGSRPPSMGPMYTQQGQRLPQHPGYPGSQQGPPRHQQALKRPYNSEGFPGQQYGPGMGGGGPYPGQPMQYHGPGPQRSAPSPSYPTHRMPLQQPSMAQYPAGPGNPSQYYKQAEQFNGQGNNHSLSSAVTTGGYSSFNQPTVNGPGRAMPGYPSSPLPGNPTPPMTPGSSMPYMSPNQDVKSPFLHDVKPNISALQPPTGNPSDDLRLTFPVRDGVVLEPFRLEHNLAVSNHVFQLRDSVYKTLMMRPDLELQFKCYHHEDRQMNTNWPASVQVSVNATPLTIERGDNKTSHKPLYLKHVCQPGRNTIQITVTACCCSHLFVLQLVHRPSVRSVLQGLMKKRLLPAEHCVTKIKRNFSSGTIPGTPGLNGEDGVEQTAIKVSLKCPITFRRIQLPARGHDCRHIQCFDLESYLQLNCERGTWRCPVCNKTALLEGLEVDQYMLGILIYIQNSDYEEITIDPVCSWKPVPVKPDLHIKEDPDGPALKRCRTLSPSHMILPSVMEMIAALGPASSPYQSLPAGGSSSTPDYPSQGGSGYSSQPGFSDFPNAPGTPTLGEFTPGPPPLSYQSDLPSGLLTPEKPVGHPMPGQMPHSSRMDPSHNPLQQQQQQHQALHGSSSMGPGAPMHSRGPSQNPRMHTDSFGLGAPGGPGDVSEPALDLLPELTNPDELLSYLGPPDLPNNSNDDLLALFESN
InterPro domains: - IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [539-677]
- IPR004181: Zinc finger, MIZ-type (domain) [579-665]
- IPR057847: ZMIZ1/ZMIZ2, GBD-like domain (domain) [416-539]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0035295 (tube development), GO:0001568 (blood vessel development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0035239 (tube morphogenesis), GO:0048514 (blood vessel morphogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0001570 (vasculogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)