Protein: DNA repair protein Rad21 (Q9UB09)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Chromosome {ECO:0000256|ARBA:ARBA00004286}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MFYEHIILAKKGPLARIWLAAHWDKKITKAHVFETNIEKSVEGILQPKVKLALRTSGHLLLGVVRIYSRKAKYLLADCNEAFVKIKMAFRPGMVDLPEGHREANVNAITLPEVFHDFDTALPELNDIDMEAQFSINQSRADEITMREDYGSLSLSLQDDGFGDIGFEAETPEIIRCSIPSNINDKIFDNDVLENIESLDPHSLDAHADMPGSRLDGDGFGDSFGQPALFEDDLFGDPSQPVEQITKESTTVLNADDSDEDAIDNIHNVPSPATSLVNSIEDEKEENNLNGHASVSENVPMNEITLVQNEDEGFALAPLDVSMYKGVTKAKRKRKLIIDEIKNISGEEMKAQLADTSDILTTLDLAPPTKRLMYWKETGGVEKLFSLPSRSIPARALFGNYNRQLFSHSTFFEDFSSVVPMEILALEFYTKENENALIIFNKKGRKRKNDNMSNLFLDHVPDSVVQSLEAPEVLRANHKSLGVSTVSVEIVSKEQESISCQNELTFFDNMRSPDLLSLNEMEQFSSINELPLTPRNMNHEMGDDFNQGDSTPAGLDHGHATPQHGNIGEMDHDSVIPTKKTAVILNESVGTSVLSDNGVSKRTNNILKGWDNYEIPSFVGQNHGDEQMENETDEQFEERVLNKRAAHLFIDVRAHFIAKDSLELSQLTSGNSRKQAAQKFYSLLVLKKFKVLHIDQSAPYADITITRGPTFENPKI
InterPro domains: - IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [653-710]
- IPR039781: Rad21/Rec8-like protein (family) [1-710]
- IPR006909: Rad21/Rec8-like protein, C-terminal, eukaryotic (domain) [658-710]
- IPR023093: ScpA-like, C-terminal (homologous_superfamily) [621-712]
- IPR006910: Rad21/Rec8-like protein, N-terminal (domain) [1-103]
- IPR049589: NXP-1, middle HEAT-repeat binding domain (domain) [327-404]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0022402 (cell cycle process), GO:0007049 (cell cycle), GO:0009893 (positive regulation of metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0021700 (developmental maturation), GO:0007059 (chromosome segregation), GO:1903047 (mitotic cell cycle process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048469 (cell maturation), GO:0048731 (system development), GO:0060255 (regulation of macromolecule metabolic process), GO:0016043 (cellular component organization), GO:0007062 (sister chromatid cohesion), GO:0000278 (mitotic cell cycle), GO:0071695 (anatomical structure maturation), GO:0022008 (neurogenesis), GO:0098813 (nuclear chromosome segregation), GO:0042551 (neuron maturation), GO:0007399 (nervous system development), GO:0140014 (mitotic nuclear division), GO:0010628 (positive regulation of gene expression), GO:0007064 (mitotic sister chromatid cohesion), GO:0006996 (organelle organization), GO:0000070 (mitotic sister chromatid segregation), GO:0030182 (neuron differentiation), GO:0010468 (regulation of gene expression), GO:0048666 (neuron development), GO:0000819 (sister chromatid segregation), GO:0048699 (generation of neurons), GO:0016322 (neuron remodeling), GO:0048285 (organelle fission), GO:0051276 (chromosome organization), GO:0000280 (nuclear division), GO:0070193 (synaptonemal complex organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0099086 (synaptonemal structure), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:0098687 (chromosomal region), GO:0044815 (DNA packaging complex), GO:0031974 (membrane-enclosed lumen), GO:0000792 (heterochromatin), GO:0000795 (synaptonemal complex), GO:0043229 (intracellular organelle), GO:0005705 (polytene chromosome interband), GO:0043228 (non-membrane-bounded organelle), GO:0043233 (organelle lumen), GO:0008278 (cohesin complex), GO:0043227 (membrane-bounded organelle), GO:0000775 (chromosome, centromeric region), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005721 (pericentric heterochromatin), GO:0070013 (intracellular organelle lumen), GO:0005634 (nucleus), GO:0031981 (nuclear lumen), GO:0005694 (chromosome), GO:0000228 (nuclear chromosome), GO:0000793 (condensed chromosome), GO:0005700 (polytene chromosome), GO:0000794 (condensed nuclear chromosome)