wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Purine permease 14 (AtPUP14) (Q9FXH5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Purine permease implicated in ATP-dependent cytokinin translocation that controls the spatiotemporal landscape of cytokinin signaling. Depletes ligands from the apoplast, which leads to a suppression of the cytokinin response.
Subcellular location: Cell membrane {ECO:0000269|PubMed:27701112}; Multi-pass membrane protein {ECO:0000305}.
Sequence: MAQNQQPIFQTKPPEQFVQIPINIERDSSTTRMNQTGNTIRKPNHWPTITISIIFVIIGQSIAKLLENFYYDKTNRSEYNENRQNDGVWTQSLLQTVGFPLLLLPFLIFITKNKRNHHQQPPITSDSIHLKSLAVIYICIGIIMSVQGRLAAMGKLEIPFGVFTLIYTAQLFFTPIFAAFINKIKFNRWVVISVILAIITGALTLSSSFGGEPDEAEENYARGSWAALFAGICFALLLCNIQNVFDSYIFKRTESTNQKPSFASVFEVIIFSSLVATIISVVGLLIAGEQHDLKREMNGFSKGKGSYVMAMVGQAVSWQVYWVGIVGLVYSVSSVLSNVISVITWPIVSVLVVIFFNFMDDEFDAFKGVALVTAVLSAAAYFFRLHKDNRMAY
InterPro domains: - IPR030182: Purine permease, plant (family) [34-389]
Interaction partners: - Adenine/guanine permease AZG2
- Equilibrative nucleotide transporter 8
- ABC transporter G family member 14
- Equilibrative nucleotide transporter 6
- Adenine/guanine permease AZG1
- Equilibrative nucleotide transporter 1
- Equilibrative nucleotide transporter 3
- E6-like protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015205 (nucleobase transmembrane transporter activity), GO:0005345 (purine nucleobase transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:0015851 (nucleobase transport), GO:0006863 (purine nucleobase transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0005794 (Golgi apparatus), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0098791 (Golgi apparatus subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0005802 (trans-Golgi network), GO:0097708 (intracellular vesicle)
Protein: NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic (EC 7.1.1.-) (NAD(P)H dehydrogenase subunit 3) (NADH-plastoquinone oxidoreductase subunit 3) (P56751)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000255|HAMAP-Rule:MF_01394}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01394}.
Sequence: MFLLYEYDIFWAFLLISSAIPVLAFLISGVLSPIRKGPEKLSSYESGIEPIGDAWLQFRIRYYMFALVFVVFDVETVFLYPWAMSFDVLGVSAFIEAFIFVLILILGLVYAWRKGALEWS
InterPro domains: - IPR000440: NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 (family) [7-120]
- IPR023043: NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid (family) [3-120]
- IPR038430: NADH:ubiquinone oxidoreductase, subunit 3 superfamily (homologous_superfamily) [1-120]
Interaction partners: - NAD
- NAD
- NAD
- NAD
- NAD
- NAD
- NAD
- NAD
- NAD
- NAD
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0008380 (RNA splicing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Cullin (Q5AJB7)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Sequence: MSSTLPPFSDLNATWTFIQPGLEYILGAHGEQGVTATVYMNCYTAVYNYCVNKSRRGTTPVSISNNSDNNSYSLAGAEIYKKLEEYLTEFIKNLKRLPNESFLEFYVRKWTRFTIGAVYMNNVFDYMNRYWVQKERSDGRKDVYDVNTLSFIKWKDEMFKPNSKLLIEQILTCIQQQRDNMIVDTNLISSAIKSLVFLSIDIQDLKKPNLIIYVNSFEIPFLEATMEYYAKESAAFLASHNVIDYMKKCETRIGEEVSRSNNYLEERTKKPLLEVLNAALIEKHANEMYDQFLVLLEQNQIDHIQRMYKLLARVQKTLDPLANTLELYIKKEAAAALEEIQTQAENSEAKKKIVEPKVYVHTLISIYNRFNDIVVRAFSKDTKFIKSLDNACRHFVNNNPIATPKPRSPCRTPELLARYADGFLKSNSKDNEMNADNLMIVFKFIAERDSFEEHYRRLLAKRLVNGTSKSEEMEESVIHRLQEENSIEYTSKMTKMFTDIKASDDLKIKFKDGMNVLFDFSPMVLARSTWPFHSSQDYNDLKLAPELKVTIDSFKAMYLQQGKGKQIEWLWNHGRAELKAHLTKGKGGKPFNFIVSQIQLMVLLAYNYSKTYTLDDLVKIVGIKKELLQNHVTPFVKYKLLKEEGDQLVIVDHYPSKKNKVSFIGAITKTKEEDVEEITKEVQQSRTIFLEASIVRIMKSKKSMAPNNLLNEVVVQAGNRFNAKNIDVKRAIDSLIDKEYLKRNGDDYEYIS
InterPro domains: - IPR036317: Cullin homology domain superfamily (homologous_superfamily) [408-661]
- IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [667-750]
- IPR045093: Cullin (family) [13-750]
- IPR016158: Cullin homology domain (domain) [411-636]
- IPR001373: Cullin, N-terminal (domain) [15-645]
- IPR016159: Cullin repeat-like-containing domain superfamily (homologous_superfamily) [11-401]
- IPR019559: Cullin protein, neddylation domain (domain) [682-749]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [596-752]
Interaction partners: - SCF ubiquitin ligase complex subunit
- E3 ubiquitin ligase complex SCF subunit
- SCF ubiquitin ligase complex subunit
- Ubiquitin-binding SDF ubiquitin ligase complex subunit
- Defective in cullin neddylation protein 1
- SCF ubiquitin ligase complex subunit
- COP9 signalosome complex subunit 5
- NEDD8 family protein
- Protein phosphatase PP2A regulatory subunit B
- Cullin-associated NEDD8-dissociated protein 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0033554 (cellular response to stress), GO:0006974 (cellular response to DNA damage stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0140535 (intracellular protein-containing complex), GO:1990234 (transferase complex), GO:0000151 (ubiquitin ligase complex), GO:0031461 (cullin-RING ubiquitin ligase complex), GO:0019005 (SCF ubiquitin ligase complex)
Protein: Aquaporin 1a (Colton blood group), tandem duplicate 2 (Aquaporin-1a.2 isoform X1) (F1QQB8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MARELKSWSFWRAVLAEFVGMTIFVFIGIASAIGNKHNRYPDQEVKVALAFGLAIATLAQSLGHISGAHLNPAITLGLLVSCQISFFRAFMYIIAQMLGAVLASGIMFKVSPDPDTTLGLNMLGNGVKVGQGFAIELFATFQLVLCVLATTDKNRTDVSGSAPLAIGLSVGLGHLVAISYTGCGINPARSFGPAVVLESFKNHWIYWIAPMCGGVAAALIYDFLLFPKREALRKRMNVLKGTADPDPSATEALIEPRSARSGSGQWPRP
InterPro domains: - IPR000425: Major intrinsic protein (family) [4-224]
- IPR034294: Aquaporin transporter (family) [3-246]
- IPR022357: Major intrinsic protein, conserved site (conserved_site) [69-77]
- IPR023271: Aquaporin-like (homologous_superfamily) [1-245]
Interaction partners: - Aquaporin-10b
- Aquaporin
- Anion exchange protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0005372 (water transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0000902 (cell morphogenesis), GO:0009887 (animal organ morphogenesis), GO:0002088 (lens development in camera-type eye), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0002089 (lens morphogenesis in camera-type eye), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0000904 (cell morphogenesis involved in differentiation), GO:0002064 (epithelial cell development), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0090596 (sensory organ morphogenesis), GO:0070306 (lens fiber cell differentiation), GO:0060429 (epithelium development), GO:0030855 (epithelial cell differentiation), GO:0048592 (eye morphogenesis), GO:0070307 (lens fiber cell development), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0043010 (camera-type eye development), GO:0048593 (camera-type eye morphogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098791 (Golgi apparatus subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0005802 (trans-Golgi network)
Protein: Microcystinase C (MlrC) (Q93CA6)
Organism: Sphingomonas sp
Function: Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC). Cleaves both linear MC and the tetrapeptide degradation product of MC. Cleaves the Adda-Glu peptide bond of linear MC heptapeptides.
Sequence: MLDRRTLMGGILSMAGSKATGAALPGRRLRVFVATLGTETNSFSPLPTGLDAFRATMLWRPGEHPDFATEATGPLWAARERAREGRYEVIEGTCAFAMPGGPVSAQAYQLLRDEILDQLRRAMPVDIVAFGLHGAMLAFGEDECEADLLERARAIVGPDVALGAELDLHAHLSQRLVRAADVLVAFKYYPHIDYVERARDLLDLLERIRAGEIMPTSSLFNCQMVAGLATQSSPMKELVADLFEFERRGEVLSGSLIQGFRAGDVARMGSKVLIYTNNDQPAAASIAQDFGRRYQAMASIMKGNGPERSFAADIELAKAATAYPVILVDSSDNPGGGASGDNMALARAMLDNDLVPSCIGPIWDPLAVQLGFEAGLGADFSLRVGGKVGEASGLPLDVRGKITGLAENVTQNLQGSRPPLGRVVCISTAGLDIIVSEIRDQCYGPDMFRALGVEPANKRYVAVKSSEQWRIGFGDMGRSVIYVASSQQSSIRHYHKRSRPMWPFEPV
InterPro domains: - IPR009197: Microcystin LR degradation protein MlrC (family) [26-507]
- IPR010799: Microcystin LR degradation protein MlrC, C-terminal (domain) [327-485]
- IPR015995: Microcystin LR degradation protein MlrC, N-terminal (domain) [30-298]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0009056 (catabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006766 (vitamin metabolic process), GO:0044282 (small molecule catabolic process), GO:1901575 (organic substance catabolic process), GO:0046483 (heterocycle metabolic process), GO:0044248 (cellular catabolic process), GO:0046700 (heterocycle catabolic process), GO:0009111 (vitamin catabolic process), GO:0044270 (cellular nitrogen compound catabolic process), GO:0006767 (water-soluble vitamin metabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0072524 (pyridine-containing compound metabolic process), GO:1901361 (organic cyclic compound catabolic process), GO:0042816 (vitamin B6 metabolic process), GO:0072526 (pyridine-containing compound catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0042597 (periplasmic space)
Protein: Opacity protein opA52 (opA31) (Q04875)
Organism: Neisseria gonorrhoeae
Function: Implicated in a number of adherence functions. OPA proteins are implicated in pathogenesis and are subject to phase variation.
Subcellular location: Cell outer membrane.
Sequence: AGEDHGRGPYVQADLAYAYEHITRDYPDAAGANKGKISTVSDYFRNIRTHSIHPRVSVGYDFGGWRIAADYARYRKWHNNKYSVNIKELERKNNKTSGGDQLNIKYQKTEHQENGTFHAVSSLGLSTVYDFRVNDKFKPYIGVRVGYGHVRHGIDSTKKTKNTLTAYHGAGTKPTYYDDIDSGKNQKNTYRQNRSSRRLGFGAMAGVGIDVAPGLTLDAGYRYHYWGRLENTRFKTHEASLGVRYRF
InterPro domains: - IPR011250: Outer membrane protein/outer membrane enzyme PagP, beta-barrel (homologous_superfamily) [8-247]
- IPR003394: Porin, opacity type (domain) [58-247]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0044403 (biological process involved in symbiotic interaction), GO:0051701 (biological process involved in interaction with host), GO:0044406 (adhesion of symbiont to host), GO:0044650 (adhesion of symbiont to host cell)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0031975 (envelope), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030312 (external encapsulating structure), GO:0009279 (cell outer membrane), GO:0019867 (outer membrane), GO:0030313 (cell envelope)
Protein: AP-1 complex subunit sigma-2 (Adaptor protein complex AP-1 subunit sigma-1B) (Adaptor-related protein complex 1 subunit sigma-1B) (Clathrin assembly protein complex 1 sigma-1B small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Sigma 1B subunit of AP-1 clathrin) (Sigma-adaptin 1B) (Sigma1B-adaptin) (P56377)
Organism: Homo sapiens (Human)
Function: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
Subcellular location: Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Sequence: MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKRYASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGGEVQETSKKNVLKAIEQADLLQEEAETPRSVLEEIGLT
InterPro domains: - IPR011012: Longin-like domain superfamily (homologous_superfamily) [2-139]
- IPR000804: Clathrin adaptor complex, small chain (conserved_site) [56-66]
- IPR022775: AP complex, mu/sigma subunit (domain) [1-140]
- IPR044733: AP-1 complex subunit sigma (family) [2-144]
- IPR016635: Adaptor protein complex, sigma subunit (family) [1-151]
Interaction partners: - AP-1 complex subunit mu-1
- AP-1 complex subunit gamma-like 2
- AP-1 complex subunit beta-1
- AP-1 complex subunit gamma-1
- AP-1 complex subunit mu-2
- AP-2 complex subunit beta
- AP-1 complex subunit sigma-1A
- Synergin gamma
- Aftiphilin
- AP-1 complex subunit sigma-3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0051179 (localization), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0051234 (establishment of localization), GO:0009605 (response to external stimulus), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:0009615 (response to virus), GO:0006810 (transport), GO:0043207 (response to external biotic stimulus), GO:0016192 (vesicle-mediated transport), GO:0006897 (endocytosis), GO:0006898 (receptor-mediated endocytosis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Alpha-S2-casein-like A (Casein alpha S2-like A) (Gamma-casein) (PP22) (Q02862)
Organism: Mus musculus (Mouse)
Function: Important role in the capacity of milk to transport calcium phosphate.
Subcellular location: Secreted.
Sequence: MKFFIFACLVVVALAKHEIKDKSSSEESSASIYPGKSKLDNSVFFQTTKDSASSSSSEESSEEVSEKIVQSEEQKVNLNQQKKFKQFSQESSFSQCCTPLHQQQQSSVNQWPQPNAIHNTPTQESISTSVEEILKKIIDMIKYIQYQQVTIPQLPQALHPQIPVSYWYPSKDYTFPNAHYTRFY
InterPro domains: - IPR011175: Alpha-s2 casein (family) [1-184]
Interaction partners: - Alpha-S1-casein
- Beta-casein
- Alpha-S2-casein-like B
- Whey acidic protein
- Kappa-casein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0050793 (regulation of developmental process), GO:0048856 (anatomical structure development), GO:0051239 (regulation of multicellular organismal process), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0050794 (regulation of cellular process), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0045595 (regulation of cell differentiation), GO:2000026 (regulation of multicellular organismal development), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0035239 (tube morphogenesis), GO:0048514 (blood vessel morphogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0060284 (regulation of cell development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Uncharacterized protein C17A2.08c (O13758)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Sequence: MRRYLKKAKPKIVQTSDNEEEKHEENLNVSQSNKNANRRKTKAKEKNSGKFRVKYENEEGDDDGEDSQIPLIPKVKKQSSFHSVDDLISRRMDALSHESGYSNAYVDELKRKSRQTPSEFTKKEEDSSTKESELQTRSSPPLPVNTSLEWNMLNQGIPEEAMIKELKDREGRKRNIAMMTDNYISLETGDQLMLAQNHKEEKLLQTEDEIQDEGYSGFENYVEESEKLQEIYHHSSESLRTRSIQMAVDQKNMEMELDDEDIAEPIQSWEHTQIKKGAFGESPAFTNGLSVKLPNILTMDEQIQRLKEAIASEKLQQEERSQIIKSLMEEELEINEQEEKIKHSFIDLDKTLLNNLTKSKS
InterPro domains: - IPR028211: Pre-mRNA-splicing factor Ntr2 (family) [100-339]
Interaction partners: - Pre-mRNA-splicing factor cwf4
- Protein NRDE2 homolog
- G-patch domain-containing protein C1486.03
- U2 small nuclear ribonucleoprotein A'
- Pre-mRNA-splicing factor cwf10
- Pre-mRNA-splicing factor brr2
- Uncharacterized protein C140.04
- Pre-mRNA-splicing factor cwf3
- Probable pre-mRNA-splicing factor ATP-dependent RNA helicase prp43
- Pre-mRNA-splicing factor cwf12
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0008380 (RNA splicing), GO:0006397 (mRNA processing), GO:0016071 (mRNA metabolic process), GO:0000398 (mRNA splicing, via spliceosome), GO:0000375 (RNA splicing, via transesterification reactions), GO:0045292 (mRNA cis splicing, via spliceosome), GO:0000377 (RNA splicing, via transesterification reactions with bulged adenosine as nucleophile)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0140513 (nuclear protein-containing complex), GO:0005737 (cytoplasm), GO:0005681 (spliceosomal complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0071014 (post-mRNA release spliceosomal complex), GO:0005634 (nucleus)