Protein: Kinesin-like protein KIF14 (F1Q554)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton, spindle. Midbody. Nucleus
Sequence: MDLSKGEVTSSFNKTKEINKTYTISALTTNGENAFKIPSKLTLQRKTSRNHHDETTQENPKRLTLQRRTRTGSLNRTKVLTEPNPAPKETQDTIKTPAKTSWGAQKATQEENKTVSTPTRRTQFEKLSVKRDVFEKLAGKDASKPTFPKPGSARGAKPPQMSSESGRSAGEKLLVGGLNRHMTPASQPAQVRRPAGLMSSSTPHGGRRVEGHTPAEGLSKMSELQTQELKMENSAVTVAVRVRPFSSREKIEKACQVIFMENQDTLVQHPDTKQTHKFTFDFSFCSINEADASFSSQQLIYEKLARPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFGEETGVIPRFCEELFSRLARSETKEMSCHLEMSYFEVYNEKIHDLLVAKDEQNQKKMPLRVREHPVYGPYVADLSTNVVSSYSDIKTWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEEEEHDHCITSRINLVDLAGSERCTSAQTSGDRLREGASINKSLLTLGKVISSLSEQSQSRKKVFTPYRESVLTWLLKESLGGNSKTAMIATLSPAASNMEESLSTLRYAQQARMIINIAKVNEDTNAKLIRDLKAEVEKLRAAQMSSQGVEPEKMRLFQQEIAALKNKLCQQEHEMAEAHRTWKEKLEEAERRKREEAKELQRAGVTFKVDNRLPNLVNLNEDPQLSEMLLYMIKEGQTKVGKLKSESAHDIQLSGALIADQHCVISSVKGTVSIKPMPNAKTFVNGHLVSECTVLHHGDRVILGGDHYFRFNHPAEVQSGKRASCWSSGDGHKDFEFAKNELLSAQRAQLEAEIQEARLKAKEEMMQGIQVAKEMAQKELSEQKSLYEIKIRALERELKEESERKREQELHKQRAASQIEQLQSVKTLLEKEVSSHKRRLQMEAQATRQAMADHDVRHAKIVAALEAEKRKIAEDLAQIEMKRALKVTQTPKMAIPQWDAMKLSLMIEEANKISGKLRKHTVFSRHEAADKEVEGGDAQLQVQVQNTKLGISTFWSLEKFQSNLAAMREIEQGESASKDDDVFYDPNDEWEPDLSASSSTSSFSRRRSRSLLKSRRISGRLYEIRVHPIQSLHCTPSQSTGLMNKPPSLHSSTSDSALPGICKDLIGSAVARLRSCQSADESESLADKLTLDLLSVHRAVRAITDLYEDLDDDSEENLFACSTEAQTHLVKATSAVERAVFITMHWVSSITFGSITVSQRAEELKMEVKKIGGYLQLLIQGCDSEISSMVTEARKRVAECMNAVFKTIGFLAAVNGTDLHLNEQNSEIIDNRSIVDCLQDGMRQSVKDLLSVGLLVTEEMLQVSHTGSTLQISKWMDVARSLQNYLRCCLSKSSDSSENHCVDYESSNLYDIQSTTTKLLKLNQAIKDLHSSLSRFLKGRRSDTSLSEAIQSSSQTIDKIISSLPHEITGRSDGLQLQDDVQSALQALLAVFSNSTDEIQKPTTDRHFVQSGYSSRNRTVPKVVYSLSSGISTCSRDARWV
InterPro domains: - IPR036961: Kinesin motor domain superfamily (homologous_superfamily) [234-603]
- IPR008984: SMAD/FHA domain superfamily (homologous_superfamily) [675-779]
- IPR032405: Kinesin-associated (domain) [631-701]
- IPR000253: Forkhead-associated (FHA) domain (domain) [702-769]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [234-588]
- IPR056523: KIF14, four-helical bundle (domain) [1148-1289]
- IPR019821: Kinesin motor domain, conserved site (conserved_site) [474-485]
- IPR001752: Kinesin motor domain (domain) [233-587]
Interaction partners: - Abnormal spindle-like microcephaly-associated protein
- Kinesin-like protein
- Condensin complex subunit 3
- Centromere protein F
- Centrosomal protein of 55 kDa
- Kinesin family member 11
- Protein regulator of cytokinesis 1
- Kinetochore protein Nuf2
- Kinesin-like protein
- Nucleolar and spindle-associated protein 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0016887 (ATP hydrolysis activity), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0016787 (hydrolase activity), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0097367 (carbohydrate derivative binding), GO:0005515 (protein binding), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:1901265 (nucleoside phosphate binding), GO:0043168 (anion binding), GO:0000166 (nucleotide binding), GO:0032553 (ribonucleotide binding), GO:0008092 (cytoskeletal protein binding), GO:0035639 (purine ribonucleoside triphosphate binding), GO:0032555 (purine ribonucleotide binding), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0017076 (purine nucleotide binding), GO:0015631 (tubulin binding), GO:0016462 (pyrophosphatase activity), GO:0005524 (ATP binding), GO:0008017 (microtubule binding), GO:0032559 (adenyl ribonucleotide binding), GO:0030554 (adenyl nucleotide binding), GO:0017111 (ribonucleoside triphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009790 (embryo development), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:1904888 (cranial skeletal system development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048701 (embryonic cranial skeleton morphogenesis), GO:0048705 (skeletal system morphogenesis), GO:0048568 (embryonic organ development), GO:0001501 (skeletal system development), GO:0048562 (embryonic organ morphogenesis), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development), GO:0048704 (embryonic skeletal system morphogenesis), GO:0048706 (embryonic skeletal system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)