Protein: ATP-dependent RNA helicase (EC 3.6.4.13) (Q57WU5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MSLAGSERAHLCVHGLTENDEQDALRHLLSATGSSQLTDISDEVVVKGAAKRKNQAATQCANSSESIKDKKTQRSSEVQQQKPDGGTVGRVKKSSDVPVKRTASKVVPVPKEVEAESVAFQADSVSHEAESLPPIAELVHKKLIRPLTEVLCINSLTRIQKLSWMPMVDKTRDVLVRSETGSGKTLAYALPLLHQLLCDCDTRPLKRDVGSVIIVLCPVRELVVQVSDVLTILTRCALFLTVGGIHGGENRHKEKARLRKGITILATTPGRLLDHLKATSSFRVEELQTIVLDEADRLLDMGFEKTIREVMDLLVAKKRDAHQTGGGDAQSSFKRVLVSATITAAVERLSHFALRDNIVRVGETEDTFSIPSSLRQHYVLVPTKHRLATLISFLRSQLDAGAQRLIVFVSTADSAEFHYYLLSRLKSPFRGKTNSGRSAGAPQKNSNRYSLKKRIGEANRHIHEGRDEDVVTFDDDSDDEDPTEVSELSEKNAVLDVNIFKLHGNMSQVDRASVFHAFKHMDSSVQPSKKGILFCTDVAARGLDMPNVDWIVHYDPPTDAPCYIHRIGRTARIGNTGDSMLFLMPHEEGYASYLSNFLAKETKLGSMAKGANAESGIIEERKYESFLFYLTKLDPKANHMWAQSTATLERAICRLVMKRHSNEENVNDESTGRTDDITRLALFAYQSYIRAYAGHSRELKRLFFNSDALHLGHVAQNFGIDKRPSEVRSQLQGLIKEDRKVARETTSVVLDDGSERPRKVLRTEVPHDDRYRSTVVQKQRKVTRDWYENKKKLEGPTYKHQQFTEFDA
InterPro domains: - IPR000629: ATP-dependent RNA helicase DEAD-box, conserved site (conserved_site) [291-299]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [46-748]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [152-378]
- IPR011545: DEAD/DEAH-box helicase domain (domain) [157-348]
- IPR001650: Helicase, C-terminal domain-like (domain) [450-615]
- IPR025313: ATP-dependent rRNA helicase SPB4-like, C-terminal extension (domain) [647-728]
Interaction partners: - rRNA biogenesis protein, putative
- Nucleolar complex protein 2
- RNA helicase
- Ribosome biogenesis protein BOP1 homolog
- ATP-dependent RNA helicase
- Nop14-like protein
- Pescadillo homolog
- ATP-dependent DEAD/H RNA helicase, putative
- U3 small nucleolar RNA-associated protein 18
- ATP-dependent RNA helicase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0042254 (ribosome biogenesis), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0034470 (ncRNA processing), GO:0006364 (rRNA processing), GO:0034660 (ncRNA metabolic process), GO:0016072 (rRNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)