Protein: Retinitis pigmentosa 9 protein (Pim-1-associated protein) (PAP-1) (Q8TA86)
Organism: Homo sapiens (Human)
Function: Is thought to be a target protein for the PIM1 kinase. May play some roles in B-cell proliferation in association with PIM1 (By similarity).
Subcellular location: Nucleus {ECO:0000250}.
Sequence: MSSRPGREDVGAAGARRPREPPEQELQRRREQKRRRHDAQQLQQLKHLESFYEKPPPGLIKEDETKPEDCIPDVPGNEHAREFLAHAPTKGLWMPLGKEVKVMQCWRCKRYGHRTGDKECPFFIKGNQKLEQFRVAHEDPMYDIIRDNKRHEKDVRIQQLKQLLEDSTSDEDRSSSSSSEGKEKHKKKKKKEKHKKRKKEKKKKKKRKHKSSKSNEGSDSE
InterPro domains: - IPR034585: Retinitis pigmentosa 9 protein (family) [1-221]
Interaction partners: - U4/U6 small nuclear ribonucleoprotein Prp31
- U4/U6 small nuclear ribonucleoprotein Prp3
- Pre-mRNA-processing-splicing factor 8
- Fascin-2
- U5 small nuclear ribonucleoprotein 200 kDa helicase
- Peripherin-2
- Inosine-5'-monophosphate dehydrogenase 1
- E3 ubiquitin-protein ligase Topors
- Ceramide kinase-like protein
- Kelch-like protein 7
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0019538 (protein metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0070647 (protein modification by small protein conjugation or removal), GO:0006396 (RNA processing), GO:0016570 (histone modification), GO:0034470 (ncRNA processing), GO:0032446 (protein modification by small protein conjugation), GO:0016574 (histone ubiquitination), GO:0034660 (ncRNA metabolic process), GO:0016180 (snRNA processing), GO:0016073 (snRNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0140534 (endoplasmic reticulum protein-containing complex), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0098796 (membrane protein complex), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0031090 (organelle membrane), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098827 (endoplasmic reticulum subcompartment), GO:0005791 (rough endoplasmic reticulum), GO:0043231 (intracellular membrane-bounded organelle), GO:0005789 (endoplasmic reticulum membrane), GO:0098588 (bounding membrane of organelle), GO:0030867 (rough endoplasmic reticulum membrane)