wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Possible osmoprotectant (Glycine betaine/carnitine/choline/L-proline) transport integral membrane protein ABC transporter ProW (O69723)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|RuleBase:RU363032}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU363032}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MHYLMTHPGAAWALTVVHLRLSLLPVLIGLMSAVPLGLLVQRAPLLRRLTTATASVIFTIPSLALFVVLPLIIGTRILDEANVIVALAAYTTALLVRAVLEALDAVPAQVHDAATAIGYSRIAQMLKVELPLSIPVLVAGLRVVAVTNIAMVSVGSVIGIGGLGTWFTAGYQTNKSDQIVAGVVAMFLLAIVVDVVINLAGRLATPWERAPRAARRRRQVAAPITGGAR
InterPro domains: - IPR051204: ABC transporter permease/solute-binding domain-containing protein (family) [2-209]
- IPR035906: MetI-like superfamily (homologous_superfamily) [10-204]
- IPR000515: ABC transporter type 1, transmembrane domain MetI-like (domain) [15-203]
Interaction partners: - Possible osmoprotectant binding lipoprotein ProX
- ABC-type quaternary amine transporter
- Possible osmoprotectant transport integral membrane protein ABC transporter ProZ
- Conserved protein
- Probable lipoprotein LpqZ
- Uncharacterized membrane protein Rv3760
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0005515 (protein binding), GO:0015562 (efflux transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response), GO:0052553 (modulation by symbiont of host immune response), GO:0052559 (induction by symbiont of host immune response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: HDC05479 (Q6IGS3)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MSQILRMLYCLPIWLLLLLRADEANGKGICLYFSEKTASWFSALTICKSLHMCLADLNTEVTLFQMKSKINQDDHEYWFGLNAHDKPTYRYVSNNKSIEYSPHNSKLVNNEGCVYVKQQNDFFKFESAKCREHRRFICTKTDECDGVSMKHGNSKCVITAEERDLVAY
InterPro domains: - IPR001304: C-type lectin-like (domain) [10-140]
- IPR016186: C-type lectin-like/link domain superfamily (homologous_superfamily) [20-147]
- IPR016187: C-type lectin fold (homologous_superfamily) [27-140]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:0030246 (carbohydrate binding), GO:0048029 (monosaccharide binding), GO:0005534 (galactose binding)
Biological Process (BP): GO:0008150 (biological process), GO:0000003 (reproduction), GO:0019953 (sexual reproduction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: glutathione transferase (EC 2.5.1.18) (A0A384P5J0)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL
InterPro domains: - IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [1-73]
- IPR036282: Glutathione S-transferase, C-terminal domain superfamily (homologous_superfamily) [76-198]
- IPR050213: Glutathione S-transferase superfamily (family) [1-196]
- IPR004046: Glutathione S-transferase, C-terminal (domain) [105-194]
- IPR010987: Glutathione S-transferase, C-terminal-like (domain) [81-199]
- IPR004045: Glutathione S-transferase, N-terminal (domain) [2-79]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016853 (isomerase activity), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0016860 (intramolecular oxidoreductase activity), GO:0046983 (protein dimerization activity), GO:0042802 (identical protein binding), GO:0043169 (cation binding), GO:0042803 (protein homodimerization activity), GO:0046872 (metal ion binding), GO:0000287 (magnesium ion binding), GO:0005509 (calcium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0007610 (behavior), GO:0044255 (cellular lipid metabolic process), GO:0006629 (lipid metabolic process), GO:0006082 (organic acid metabolic process), GO:0007626 (locomotory behavior), GO:0006631 (fatty acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0033559 (unsaturated fatty acid metabolic process), GO:0006692 (prostanoid metabolic process), GO:0032787 (monocarboxylic acid metabolic process), GO:0006690 (icosanoid metabolic process), GO:0006693 (prostaglandin metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Pregnancy specific beta-1-glycoprotein 18 (E9Q8L0)
Organism: Mus musculus (Mouse)
Function: Not known
Sequence: MELSSELFSNGCTSWQRVLLTASLFICVRPTTLISPTIELVPASVAAGGSILLLVHNIPKYLQSLFWYKGLIAFNKVEIARYRTAKNSGEPGPAHSGRETVYSNGSLLLQNVTWKDTGFYTLRTLTRYQKMEFAHIYLQVDTSHSLCCDTLDSAQLSIDPVPRHAAEGGSVLLQVHNLPEDVQTFSWYKGVLSTQDFKIAEYSIATKSIIRGRAHSRREIGYTNGSLLLQDVTEKDSGLYTLITIDSNVRVVTAHVQVNIHRK
InterPro domains: - IPR013106: Immunoglobulin V-set domain (domain) [44-260]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [36-260]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [37-263]
- IPR003599: Immunoglobulin domain subtype (domain) [40-259]
- IPR050831: Carcinoembryonic antigen-related cell adhesion (family) [1-140]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097367 (carbohydrate derivative binding), GO:1901681 (sulfur compound binding), GO:0005515 (protein binding), GO:0043395 (heparan sulfate proteoglycan binding), GO:0043394 (proteoglycan binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009893 (positive regulation of metabolic process), GO:0042445 (hormone metabolic process), GO:0065008 (regulation of biological quality), GO:0009058 (biosynthetic process), GO:0051239 (regulation of multicellular organismal process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0019222 (regulation of metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0001817 (regulation of cytokine production), GO:0010817 (regulation of hormone levels), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0009690 (cytokinin metabolic process), GO:0046483 (heterocycle metabolic process), GO:0042446 (hormone biosynthetic process), GO:0009308 (amine metabolic process), GO:0032653 (regulation of interleukin-10 production), GO:0010628 (positive regulation of gene expression), GO:0010468 (regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009986 (cell surface)
Protein: UPF0415 protein C7orf25 (Q9BPX7)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MSAHSMLCERIAIAKELIKRAESLSRSRKGGIEGGAKLCSKLKAELKFLQKVEAGKVAIKESHLQSTNLTHLRAIVESAENLEEVVSVLHVFGYTDTLGEKQTLVVDVVANGGHTWVKAIGRKAEALHNIWLGRGQYGDKSIIEQAEDFLQASHQQPVQYSNPHIIFAFYNSVSSPMAEKLKEMGISVRGDIVAVNALLDHPEELQPSESESDDEGPELLQVTRVDRENILASVAFPTEIKVDVCKRVNLDITTLITYVSALSYGGCHFIFKEKVLTEQAEQERKEQVLPQLEAFMKDKELFACESAVKDFQSILDTLGGPGERERATVLIKRINVVPDQPSERALRLVASSKINSRSLTIFGTGDTLKAITMTANSGFVRAANNQGVKFSVFIHQPRALTESKEALATPLPKDYTTDSEH
InterPro domains: - IPR010733: Domain of unknown function DUF1308 (domain) [248-409]
- IPR041076: Domain of unknown function DUF5614 (domain) [1-217]
Interaction partners: - Proteasome subunit alpha type-2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0019222 (regulation of metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0009892 (negative regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0044248 (cellular catabolic process), GO:0046700 (heterocycle catabolic process), GO:0010629 (negative regulation of gene expression), GO:0010468 (regulation of gene expression), GO:0016070 (RNA metabolic process), GO:0031047 (RNA-mediated gene silencing), GO:0006402 (mRNA catabolic process), GO:0006401 (RNA catabolic process), GO:0016071 (mRNA metabolic process), GO:0000956 (nuclear-transcribed mRNA catabolic process), GO:0000184 (nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Feruloyl esterase C (EC 3.1.1.73) (Ferulic acid esterase C) (FAEC) (Q5B2G3)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Involved in degradation of plant cell walls. Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans, and the feruloyl-galactose ester bond in pectin. Active against paranitrophenyl-acetate, methyl ferulate and wheat arabinoxylan.
Subcellular location: Secreted {ECO:0000305}.
Sequence: MLRAVLLPTLLAFGAFTPVHGANSPGCGKQPTLTNGVNQINGREYVLKIPDGYDPSKPHHLIFGLHWRGGNMYNVVNGDSIQPWYGLEARAQGSAIFVAPNGLNAGWANTNGEDVAFIDAIMEQVEDDLCVDQASRFATGFSWGGGMSYALACARAAEFRAVSVLSGGLISGCDGGNDPIAYLGIHGINDPVLPLDGGVTLANTFVSNNGCQPTDIGQPASGSGGSVRTDFSGCSHPVSFIAYDGGHDGAPLGVGSSLAPDATWEFFMAA
InterPro domains: - IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [38-266]
- IPR043595: Feruloyl esterase B/C/D (family) [3-269]
Interaction partners: - Xylanolytic transcriptional activator xlnR
- Probable D-xylulose reductase A
- Probable feruloyl esterase B
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0052689 (carboxylic ester hydrolase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009056 (catabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901575 (organic substance catabolic process), GO:0043170 (macromolecule metabolic process), GO:0005975 (carbohydrate metabolic process), GO:0016052 (carbohydrate catabolic process), GO:0009057 (macromolecule catabolic process), GO:0005976 (polysaccharide metabolic process), GO:0000272 (polysaccharide catabolic process), GO:0044042 (glucan metabolic process), GO:0009251 (glucan catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: N-acetyltransferase ESCO zinc-finger domain-containing protein (Q38BS8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MTKQQMCLRDFFLKGKKGMIKDACSDVIDLHVAVKGDELVDAFSSKEKHEFLDSMPPMKHSTDVSASCYLDDNVPESSSSNHGEGSTLARPSGVTAFPFQTKHVGKYGALTTRSSKRPRSGAQTCLDFGQSDIGGVTTCRICGMIYNAVMPEDIRLHRRFCRPQALSNKRRKELDAADGHCVWLASRDVIVQLDRLAGSQRQNLAMQRRYRAGAAPVCLKVQESTADEFICYVLECGARGLARSAVVSRFVEALQFDDVTLQGESDYCLVAVVQVYLERLVCVVAGRPVARTHEPTLLPYKNHCETALGGKQYLETSQKTLCDVPYIWLQSELVLATTWRGCLQQQIAPAVKSQRDVTRDFFKCRGMASEKKFEDLQQTRSLGDAALSRALSTLGRHVTYGCALCPRRQFSYDSSVVNESVLHRVAGVMGCDDVSTLYTHTGASSHFQ
InterPro domains: - IPR028005: N-acetyltransferase ESCO, zinc-finger (domain) [123-162]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016407 (acetyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0022402 (cell cycle process), GO:0006807 (nitrogen compound metabolic process), GO:0007049 (cell cycle), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0007059 (chromosome segregation), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0044786 (cell cycle DNA replication), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0006259 (DNA metabolic process), GO:0006260 (DNA replication), GO:0006270 (DNA replication initiation), GO:0006261 (DNA-templated DNA replication)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Heat shock protein 70 (Hsp 70) family protein (B3H683)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MLSKARVVSWRSGNVKSGMLSKARVVSWRAGNANGHGERSRVACSERQRKELIDTKNTADTTIYSIEKSLGEYREKIPSEIAKEIEDAVADLRSASSGDDLNEIKAKIEAANKAVSKIGEHMSGGSGGGSAPGGGSEGGSDQAPEAEYEEVKK
InterPro domains: - IPR013126: Heat shock protein 70 family (family) [40-122]
- IPR029048: Heat shock protein 70kD, C-terminal domain superfamily (homologous_superfamily) [41-124]
Interaction partners: - At3g17830
- Heat shock protein 90-6, mitochondrial
- Mitochondrial import inner membrane translocase subunit TIM44-2
- Mitochondrial import inner membrane translocase subunit TIM44-1
- Elongation factor G-1, mitochondrial
- Elongation factor G-2, mitochondrial
- Similar to part of disease resistance protein domain family protein)
- Heat shock 70 kDa protein 17
- AT4g14060/dl3070w
- Major latex protein-like
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009628 (response to abiotic stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0006950 (response to stress), GO:0009408 (response to heat), GO:0009266 (response to temperature stimulus), GO:0016043 (cellular component organization), GO:0010286 (heat acclimation), GO:0006996 (organelle organization), GO:0007005 (mitochondrion organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Biogenesis of lysosome-related organelles complex 1 subunit 4 (BLOC-1 subunit 4) (Protein cappuccino homolog) (Q9NUP1)
Organism: Homo sapiens (Human)
Function: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking.
Subcellular location: Cytoplasm {ECO:0000250}.
Sequence: MEGSFSDGGALPEGLAEEAEPQGAAWSGDSGTVSQSHSSASGPWEDEGAEDGAPGRDLPLLRRAAAGYAACLLPGAGARPEVEALDASLEDLLTRVDEFVGMLDMLRGDSSHVVSEGVPRIHAKAAEMRRIYSRIDRLEAFVRMVGGRVARMEEQVTKAEAELGTFPRAFKKLLHTMNVPSLFSKSAPSRPQQAGYEAPVLFRTEDYFPCCSERPQL
InterPro domains: - IPR024857: Cappuccino (family) [19-216]
Interaction partners: - Biogenesis of lysosome-related organelles complex 1 subunit 6
- Biogenesis of lysosome-related organelles complex 1 subunit 1
- Biogenesis of lysosome-related organelles complex 1 subunit 5
- Dysbindin
- Biogenesis of lysosome-related organelles complex 1 subunit 3
- Biogenesis of lysosome-related organelles complex 1 subunit 2
- SNARE-associated protein Snapin
- BLOC-2 complex member HPS6
- BLOC-2 complex member HPS3
- BLOC-2 complex member HPS5
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0071840 (cellular component organization or biogenesis), GO:0051640 (organelle localization), GO:0051649 (establishment of localization in cell), GO:0016043 (cellular component organization), GO:0046907 (intracellular transport), GO:0006810 (transport), GO:0051656 (establishment of organelle localization), GO:0051647 (nucleus localization), GO:0007097 (nuclear migration), GO:0006996 (organelle organization), GO:0010256 (endomembrane system organization), GO:0007030 (Golgi organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0140535 (intracellular protein-containing complex), GO:0031082 (BLOC complex), GO:0031083 (BLOC-1 complex)
Protein: Outer membrane usher protein FimD (P30130)
Organism: Escherichia coli (strain K12)
Function: Involved in the export and assembly of FimA fimbrial subunits across the outer membrane.
Subcellular location: Cell outer membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Sequence: MSYLNLRLYQRNTQCLHIRKHRLAGFFVRLVVACAFAAQAPLSSADLYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVAGMNLLADDACVPLTTMVQDATAHLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDRSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEKTRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR
InterPro domains: - IPR000015: Outer membrane usher protein (family) [26-878]
- IPR018030: Fimbrial membrane usher, conserved site (conserved_site) [325-335]
- IPR025885: PapC, N-terminal domain (domain) [48-192]
- IPR043142: PapC-like, C-terminal domain superfamily (homologous_superfamily) [796-878]
- IPR025949: PapC-like, C-terminal domain (domain) [799-863]
- IPR042186: Outer membrane usher protein FimD, plug domain (homologous_superfamily) [705-795]
- IPR037224: PapC, N-terminal domain superfamily (homologous_superfamily) [46-170]
Interaction partners: - Chaperone protein FimC
- Type 1 fimbrin D-mannose specific adhesin
- Protein FimG
- Protein FimF
- Fimbrin-like protein FimI
- Type-1 fimbrial protein, A chain
- Probable fimbrial chaperone SfmC
- Uncharacterized fimbrial chaperone YqiH
- Probable fimbrial chaperone YadV
- Probable fimbrial chaperone protein ElfD
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:1901681 (sulfur compound binding), GO:0097367 (carbohydrate derivative binding), GO:0008201 (heparin binding), GO:0005539 (glycosaminoglycan binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0033554 (cellular response to stress), GO:0006974 (cellular response to DNA damage stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0031975 (envelope), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030312 (external encapsulating structure), GO:0009279 (cell outer membrane), GO:0019867 (outer membrane), GO:0030313 (cell envelope)