wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Cilia- and flagella-associated protein 107 (Q2TA11)
Organism: Bos taurus (Bovine)
Function: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:34715025}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:37327785}.
Sequence: MQFLTAVSPQSSSTPSWKIETKYSTRVLTGNWTEERRKFIKATEKTPQTIYRKEYVPFPGHRPDQISRWYSKRTVEGLPYKYLITHHQEPSQRYLISTYDDHYNRHNYHPGLPELRTWNRHKLLWLPEKADFPLLGPPTNYGLYEQLKQKWLPPPEATLRESIYTSSYPRPPAGAMSRREHAIPVPPPRLQPVPHF
InterPro domains: - IPR054709: Cilia- and flagella-associated protein 107 (family) [20-189]
- IPR037662: Cilia- and flagella-associated protein 68/107 (family) [2-190]
Interaction partners: - EF-hand domain-containing family member B
- Tektin-3
- Tektin-4
- Tektin-1
- RIB43A-like with coiled-coils protein 2
- EF-hand domain-containing family member C2
- Cilia- and flagella-associated protein 276
- EF-hand domain-containing protein 1
- Parkin coregulated gene protein
- Protein Flattop
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0070647 (protein modification by small protein conjugation or removal), GO:0032446 (protein modification by small protein conjugation), GO:0016567 (protein ubiquitination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0005930 (axoneme), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0005879 (axonemal microtubule), GO:0005881 (cytoplasmic microtubule), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0099568 (cytoplasmic region), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0005929 (cilium), GO:0032838 (plasma membrane bounded cell projection cytoplasm), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0099513 (polymeric cytoskeletal fiber), GO:0097014 (ciliary plasm), GO:0005874 (microtubule), GO:0015630 (microtubule cytoskeleton)
Protein: Probable thioesterase YBR096W (EC 2.3.1.-) (P38256)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Not known
Sequence: MGVCTIFRWLFAAYLLSSYKSLPGAYFVRFYYYVIQNLFLPMFTGFETENIKKLEKNEYGCFSYTSLDTYASPFECDFYFHKSNSTYFAELDISRGNLMCKIFQKLMLNSKHYPYIPVANVFTNFLKEIKPFQKYSVSSRIICWDEKWIYVMSRFTIKKGTVLCSLSLTKYVLKDGRKTIKPKDALEYCGLYNEKVAKISEDNLKLLTERCGFHETVPLENLSQEYCSEI
InterPro domains: - IPR029069: HotDog domain superfamily (homologous_superfamily) [67-187]
- IPR051490: THEM6/lcsJ thioesterase (family) [3-200]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0008374 (O-acyltransferase activity), GO:0016407 (acetyltransferase activity), GO:0016413 (O-acetyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0006629 (lipid metabolic process), GO:0006082 (organic acid metabolic process), GO:0006631 (fatty acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0001676 (long-chain fatty acid metabolic process), GO:0032787 (monocarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Tetratricopeptide repeat domain-containing protein PYG7, chloroplastic (Protein PALE YELLOW GREEN 7 homolog) (C0PEY7)
Organism: Zea mays (Maize)
Function: Nuclear genome-encoded factor required for the accumulation of photosystem I (PSI). Functions as PSI biogenesis factor. Cooperates with PSA3 to promote the stable assembly of PSI in the thylakoid membrane. May target primarily the PsaC subunit.
Subcellular location: Plastid, chloroplast thylakoid membrane {ECO:0000250|UniProtKB:B9DHG0}; Multi-pass membrane protein {ECO:0000255}. Note=Copurifies with PSI. {ECO:0000250|UniProtKB:B9DHG0}.
Sequence: MARLLLFPSQACVDPGRHLLLHPPVSRPRAVRSGPPPAAPRRTGVVSLPGRCPPPLCWNHHPFLPCRSSKRGWVVFASENVQEISSHLPRKDERRSGNLLLRFSALPYCTMAWLSTAQLAQSSVGEKLNMVYEVGELFELGIQLSYLLILIGLLGAGTFFVIRQVLVRRELDLSAKELQEQVRSGDASATEYFELGAVMLRRKFYPAAIKYLQQAIDKWDRDEQDLAQVYNALGVSYKRENKLDKAIQQFQKAVELQPGYVTAWNNLGDAYEQQKDLKSALKAFEEVLLFDPNNKVARPRVDDLRPRVSMYKGVPVKSEKR
InterPro domains: - IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [184-305]
- IPR019734: Tetratricopeptide repeat (repeat) [189-294]
- IPR047150: SGT (family) [187-297]
Interaction partners: - Photosystem I assembly factor PSA3, chloroplastic
- Toc64
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044237 (cellular metabolic process), GO:0016043 (cellular component organization), GO:0006091 (generation of precursor metabolites and energy), GO:0015979 (photosynthesis), GO:0044085 (cellular component biogenesis), GO:0019684 (photosynthesis, light reaction), GO:0043933 (protein-containing complex organization), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0034357 (photosynthetic membrane), GO:0043229 (intracellular organelle), GO:0019867 (outer membrane), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0043228 (non-membrane-bounded organelle), GO:0009526 (plastid envelope), GO:0042170 (plastid membrane), GO:0009507 (chloroplast), GO:0042651 (thylakoid membrane), GO:0031968 (organelle outer membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031976 (plastid thylakoid), GO:0098588 (bounding membrane of organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0009535 (chloroplast thylakoid membrane), GO:0009534 (chloroplast thylakoid), GO:0009579 (thylakoid), GO:0055035 (plastid thylakoid membrane)
Protein: Dicarboxylate carrier 3, isoform A (FI08040p) (A1Z787)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MGEDSSRRLPRWWFGGVCAAIAVTGTHPIDLIKVQLQTQSQADRKTVGEILKGIHERSGILGFYNGISASWFRQLTYTTTRFALYEAGKDYVDTQKVSSKMALATFAGIVGGIVGVPGDVVTVRLQNDVKLPEEKRRNYKHVFDGLFRIYKEEGVSSLFRGTVPAVSRAVLLTIGTNAAYDQVKQMLKIATGAGEGVPLHFATSTIAGCIAVVITQPLDVIKTTFMNAQPGEFSGIGGAFLSTAKQGPLAFYKGFIPALIRVSPNTIITFVLYEQARMRFGYLPPDK
InterPro domains: - IPR018108: Mitochondrial carrier protein, transmembrane region (repeat) [6-279]
- IPR023395: Mitochondrial carrier protein domain superfamily (homologous_superfamily) [9-282]
- IPR002067: Mitochondrial carrier protein (family) [11-226]
- IPR050391: Mitochondrial Metabolite Transporter (family) [9-277]
Interaction partners: - Lethal
- Uncharacterized protein
- LD13176p
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901682 (sulfur compound transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0005315 (inorganic phosphate transmembrane transporter activity), GO:0015116 (sulfate transmembrane transporter activity), GO:0015103 (inorganic anion transmembrane transporter activity), GO:0015291 (secondary active transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0098660 (inorganic ion transmembrane transport), GO:0006810 (transport), GO:0072348 (sulfur compound transport), GO:0071705 (nitrogen compound transport), GO:0098661 (inorganic anion transmembrane transport), GO:0015698 (inorganic anion transport), GO:0035435 (phosphate ion transmembrane transport), GO:0006817 (phosphate ion transport), GO:0008272 (sulfate transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Hexose transporter HXT8 (P40886)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Probable glucose transporter.
Subcellular location: Membrane; Multi-pass membrane protein.
Sequence: MTDRKTNLPEEPIFEEAEDDGCPSIENSSHLSVPTVEENKDFSEYNGEEAEEVVVPEKPASAYATVSIMCLCMAFGGFMSGWDTGTISGFVNQTDFLRRFGNYSHSKNTYYLSNVRTGLIVSIFNVGSAIGCLFLSKLGDIYGRCMGLIIVIVVYMVGIVIQIASIDKWYQYFIGRIIAGIGAGSISVLAPMLISETAPKHIRGTLLACWQLMVTFAIFLGYCTNYGTKTYSNSVQWRVPLGLCFAWAIIMIGGMTFVPESPRFLVQVGKIEQAKASFAKSNKLSVDDPAVVAEIDLLVAGVEAEEAMGTASWKELFSRKTKVFQRLTMTVMINSLQQLTGDNYFFYYGTTIFKSVGMNDSFETSIVLGIVNFASCFFSLYSVDKLGRRRCLLLGAATMTACMVIYASVGVTRLYPNGKSEPSSKGAGNCTIVFTCFYIFCFSCTWGPVCYVIISETFPLRVRSKCMSVATAANLLWGFLIGFFTPFITSAINFYYGYVFMGCLAFSYFYVFFFVPETKGLTLEEVDEMWMDGVLPWKSESWVPASRRDGDYDNEKLQHDEKPFYKRMF
InterPro domains: - IPR036259: MFS transporter superfamily (homologous_superfamily) [60-532]
- IPR020846: Major facilitator superfamily domain (domain) [69-519]
- IPR005829: Sugar transporter, conserved site (conserved_site) [178-396]
- IPR050360: Major Facilitator Superfamily Sugar Transporters (family) [59-547]
- IPR003663: Sugar/inositol transporter (family) [42-526]
- IPR005828: Major facilitator, sugar transporter-like (family) [69-530]
Interaction partners: - Carbon catabolite-derepressing protein kinase
- Uncharacterized protein YKR075C
- Uncharacterized globin-like protein YNL234W
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015144 (carbohydrate transmembrane transporter activity), GO:0051119 (sugar transmembrane transporter activity), GO:0015145 (monosaccharide transmembrane transporter activity), GO:0015149 (hexose transmembrane transporter activity), GO:0015578 (mannose transmembrane transporter activity), GO:0005355 (glucose transmembrane transporter activity), GO:0005353 (fructose transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0034219 (carbohydrate transmembrane transport), GO:0006810 (transport), GO:0015749 (monosaccharide transmembrane transport), GO:0071702 (organic substance transport), GO:0008645 (hexose transmembrane transport), GO:0008643 (carbohydrate transport), GO:1904659 (glucose transmembrane transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Mitochondrial outer membrane protein OM14 C-terminal domain-containing protein (Q5A8Z9)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Sequence: MSSKAPSNEQIKKDVKKDADNIAKKGKEESEHLKKQGKEAVDEASEKGKEFIDQANKKGKELLDEANDKSKEFLKEARKELNHLEEEGQNLLSQFVAYVKSTANSIGQSLNKAGAELQSATSAAVSRTSVELQNPVVIAQIAVAAGGAAAGYLAYLERYRINTDNKYVVGIHASIITGLVVLDGYLFSTYYPKYDKKVAK
InterPro domains: - IPR039453: Mitochondrial outer membrane protein OM14, C-terminal (domain) [130-197]
- IPR039454: Mitochondrial outer membrane protein OM14 (family) [3-197]
Interaction partners: - Uncharacterized protein
- tRNA threonylcarbamoyladenosine dehydratase
- Prn4p
- Tea1p
- SNAP receptor
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0040007 (growth), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0030447 (filamentous growth), GO:0009628 (response to abiotic stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0006950 (response to stress), GO:0071554 (cell wall organization or biogenesis), GO:0009408 (response to heat), GO:0009266 (response to temperature stimulus), GO:0016043 (cellular component organization), GO:0044182 (filamentous growth of a population of unicellular organisms), GO:0071852 (fungal-type cell wall organization or biogenesis), GO:0071555 (cell wall organization), GO:0033554 (cellular response to stress), GO:0031505 (fungal-type cell wall organization), GO:0006996 (organelle organization), GO:0034605 (cellular response to heat)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Keratin, type I cytoskeletal 17 (Cytokeratin-17) (Keratin-17) (K7EPJ9)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: GSSGLGGGSSRTSCRLSGGLGAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK
InterPro domains: - IPR002957: Keratin, type I (family) [8-222]
- IPR039008: Intermediate filament, rod domain (domain) [68-231]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0045103 (intermediate filament-based process), GO:0042303 (molting cycle), GO:0016043 (cellular component organization), GO:0042633 (hair cycle), GO:0044085 (cellular component biogenesis), GO:0009888 (tissue development), GO:0030154 (cell differentiation), GO:0045104 (intermediate filament cytoskeleton organization), GO:0048513 (animal organ development), GO:0031069 (hair follicle morphogenesis), GO:0001942 (hair follicle development), GO:0043588 (skin development), GO:0060429 (epithelium development), GO:0006996 (organelle organization), GO:0045109 (intermediate filament organization), GO:0008544 (epidermis development), GO:0097435 (supramolecular fiber organization), GO:0030855 (epithelial cell differentiation), GO:0022607 (cellular component assembly), GO:0007010 (cytoskeleton organization), GO:0009913 (epidermal cell differentiation), GO:0030216 (keratinocyte differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005615 (extracellular space), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0005576 (extracellular region), GO:0070062 (extracellular exosome), GO:0043227 (membrane-bounded organelle), GO:0043230 (extracellular organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:1903561 (extracellular vesicle)
Protein: Heme oxygenase PigA (EC 1.14.99.58) (G3XCZ8)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Involved in heme degradation. Catalyzes the degradation of heme to biliverdin, with the release of iron. Forms biliverdin delta (70%) and beta (30%).
Sequence: MDTLAPESTRQNLRSQRLNLLTNEPHQRLESLVKSKEPFASRDNFARFVAAQYLFQHDLEPLYRNEALARLFPGLASRARDDAARADLADLGHPVPEGDQSVREADLSLAEALGWLFVSEGSKLGAAFLFKKAAALELDENFGARHLAEPEGGRAQGWKSFVAILDGIELNEEEERLAAKGASDAFNRFGDLLERTFA
InterPro domains: - IPR016053: Haem oxygenase-like (family) [15-194]
- IPR016084: Haem oxygenase-like, multi-helical (homologous_superfamily) [1-198]
Interaction partners: - Heme uptake outer membrane receptor HasR
- Heme/hemoglobin uptake outer membrane receptor PhuR
- Bacterioferritin BfrB
- Bacterial ferritin
- Bacteriophytochrome
- ferroxidase
- Ferrochelatase
- Protoheme IX farnesyltransferase 2
- Protoheme IX farnesyltransferase 1
- Heme oxygenase, BphO
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016835 (carbon-oxygen lyase activity), GO:0016836 (hydro-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0042440 (pigment metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0042168 (heme metabolic process), GO:0046483 (heterocycle metabolic process), GO:0046148 (pigment biosynthetic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0033013 (tetrapyrrole metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0018130 (heterocycle biosynthetic process), GO:0006783 (heme biosynthetic process), GO:0006778 (porphyrin-containing compound metabolic process), GO:0033014 (tetrapyrrole biosynthetic process), GO:0006779 (porphyrin-containing compound biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: eRF1 methyltransferase catalytic subunit mtq2 (eRF1 MTase catalytic subunit mtq2) (EC 2.1.1.297) (N(5)-glutamine methyltransferase catalytic subunit mtq2) (Q9UT94)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Methylates eRF1 on 'Gln-182' using S-adenosyl L-methionine as methyl donor. eRF1 needs to be complexed to eRF3 in its GTP-bound form to be efficiently methylated.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Sequence: MLSTPVTSQLRLKEFQDVYEPAEDTFALLDALEKDAKKLRQMAEMKNLLTAEIGCGSGCASSFLKSGILKNKPIVHFMSDISNSACRASKITALNNRELYKDDNGLFITVQTSFLDGIRLGNGVDILIFNPPYVPTEFEEIPSEAATIASAWAGGTDGMDVTSTLLNQLKDILSQDGVFYMVAVARNKLHSICEILQKDGFIVNETLKRKAGRETLSILRIYRIGNTIWDE
InterPro domains: - IPR002052: DNA methylase, N-6 adenine-specific, conserved site (conserved_site) [127-133]
- IPR029063: S-adenosyl-L-methionine-dependent methyltransferase superfamily (homologous_superfamily) [11-227]
- IPR052190: Eukaryotic/Archaeal PrmC-Related Methyltransferase (family) [2-223]
Interaction partners: - Multifunctional methyltransferase subunit trm112
- Putative peptide chain release factor 1, mitochondrial
- tRNA
- 18S rRNA
- Probable MRF1 mitochondrial N
- Eukaryotic peptide chain release factor subunit 1
- Protein arginine N-methyltransferase 2
- Protein arginine N-methyltransferase 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016740 (transferase activity), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0140097 (catalytic activity, acting on DNA), GO:0009008 (DNA-methyltransferase activity), GO:0008168 (methyltransferase activity), GO:0008757 (S-adenosylmethionine-dependent methyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0032259 (methylation), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0043414 (macromolecule methylation), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0006479 (protein methylation), GO:0008213 (protein alkylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)