wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Transmembrane protein 176B (Protein LR8) (Q9R1Q6)
Organism: Mus musculus (Mouse)
Function: May play a role in the process of maturation of dendritic cells (By similarity). Required for the development of cerebellar granule cells.
Subcellular location: Nucleus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Sequence: MVQSTVTVNGVKVASTHPQSAHISIHIHQKSALEQLLGAVGSLKKFLSWPQARIHYGQLSLGVTQILLGLVSCALGVCLYFGPWTELCAFGCAFWSGSVAILAGVGTIVHEKRQGKLSGQVSCLLLLACIATAAAATVLGVNSLIRQTSVPYYVEIFSTCNPLQSSMDPGYGTVRYSDDSDWKTERCREYLNMMMNLFLAFCIMLTVVCILEIVVSVASLGLSLRSMYGRSSQALNEEESERKLLDGHPAPASPAKEKIPAIL
InterPro domains: - IPR007237: CD20-like family (family) [61-223]
- IPR009281: Transmembrane protein 176A/B (family) [1-262]
Interaction partners: - Transmembrane protein 176A
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0030154 (cell differentiation), GO:0048468 (cell development), GO:0002244 (hematopoietic progenitor cell differentiation), GO:0030097 (hemopoiesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)
Protein: PRA1 family protein H (AtPRA1.H) (Q8LFP1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in both secretory and endocytic intracellular trafficking in the endosomal/prevacuolar compartments.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:18583532}; Multi-pass membrane protein {ECO:0000269|PubMed:18583532}.
Sequence: MAFSPNPLSLSVPDPAFESWLRDSGYLELLDHRTSAAAAAASSSASVSSSAAATSAASDDVVSSITGGFFASLLSRLVTVSSLLTINPFSKLSADDFSGDTTPWTTGFIGNCDSYSFPSSSQQARMRVHENIKRFARNYATLFIVFFACALYQMPLALVGLLGSLALWELFKYCSDKWKFDRHPSMRKLSIGIGQCATAVLLTFLNVQMALFSALAISYSVMILHAGFRKLTPSKKPTRGR
InterPro domains: - IPR004895: Prenylated rab acceptor PRA1 (family) [92-230]
Interaction partners: - PRA1 family protein A2
- PRA1 family protein A3
- PRA1 family protein C
- PRA1 family protein G2
- PRA1 family protein E
- PRA1 family protein B5
- PRA1 family protein G1
- PRA1 family protein A1
- PRA1 family protein F3
- PRA1 family protein B1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Ribosome modulation factor (RMF) (Hibernation factor RMF) (Protein E) (P0AFW2)
Organism: Escherichia coli (strain K12)
Function: During stationary phase, converts 70S ribosomes to an immature dimeric form (90S ribosomes) which are converted to inactive 100S ribosomes (a process called ribosomal hibernation) by the hibernation promoting factor HPF. Inactivates ribosomes by covering the peptidyl transferase (PTase) center of the 23S rRNA and the entrance of peptide exit tunnel. However crystallization with T.thermophilus 70S ribosomes shows it binds near the 3'-end of the 16S rRNA near the anti-Shine-Dalgarno sequence, where it would sterically hinder translation inititation. In this crystal binding of RMF induces movement of the 30S head domain away from the rest of the ribosome, presumably so they would more easily form dimers. Also involved in protection against heat stress, but this role is not dependent on the maintenance of ribosome dimers.
Subcellular location: Cytoplasm {ECO:0000305}.
Sequence: MKRQKRDRLERAHQRGYQAGIAGRSKEMCPYQTLNQRSQWLGGWREAMADRVVMA
InterPro domains: - IPR007040: Ribosome modulation factor (family) [1-55]
- IPR023200: Ribosome modulation factor domain superfamily (homologous_superfamily) [1-55]
Interaction partners: - Ribosome hibernation promoting factor
- Ribosome-associated inhibitor A
- Elongation factor Tu 2
- Elongation factor Tu 1
- Cold shock-like protein CspC
- Uncharacterized protein YaeQ
- Cell division topological specificity factor
- Uncharacterized protein YodC
- Protein YobF
- Protease 7
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0071840 (cellular component organization or biogenesis), GO:0009892 (negative regulation of metabolic process), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0043933 (protein-containing complex organization), GO:0006996 (organelle organization), GO:0010629 (negative regulation of gene expression), GO:0010468 (regulation of gene expression), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0065003 (protein-containing complex assembly), GO:0042254 (ribosome biogenesis), GO:0022618 (ribonucleoprotein complex assembly), GO:0042273 (ribosomal large subunit biogenesis), GO:0071826 (ribonucleoprotein complex subunit organization), GO:0042255 (ribosome assembly), GO:0140694 (non-membrane-bounded organelle assembly), GO:0000027 (ribosomal large subunit assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Aspartate-beta-hydroxylase (A0A096MK70)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Sarcoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004157}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004157}.
Sequence: MAPRKNAKGGGGNSSSSGSGSGSGSPSTGSSGSSSSPGARREAKHGGHKNGRRGGISGGSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLGKLGVYDADGDGDFDVDDAKVLLGLKERSTSERTFPPEEAETQAELEEQAPEGAEAQNVEDEVKEQIQSLLQESVHTDHDLEADGPAGEPQSEVEDFLTATDSDDRFEALEPGTVHEDTEDSYHVEETASQNHPNDAEEVMSEQESSDHGEAVTDDGLQQHAEEVRHEDYDEPVYEPSENERIEISDNAIDDSNIISEEINVASVEEQQDTPPDT
InterPro domains: - IPR039038: Aspartyl/asparaginyl beta-hydroxylase family (family) [1-305]
- IPR007943: Aspartyl beta-hydroxylase/Triadin domain (domain) [50-115]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0042592 (homeostatic process), GO:0048878 (chemical homeostasis), GO:0019725 (cellular homeostasis), GO:0050801 (monoatomic ion homeostasis), GO:0055082 (intracellular chemical homeostasis), GO:0098771 (inorganic ion homeostasis), GO:0006873 (intracellular monoatomic ion homeostasis), GO:0055074 (calcium ion homeostasis), GO:0055080 (monoatomic cation homeostasis), GO:0006874 (intracellular calcium ion homeostasis), GO:0030003 (intracellular monoatomic cation homeostasis), GO:0051480 (regulation of cytosolic calcium ion concentration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0031984 (organelle subcompartment), GO:0099080 (supramolecular complex), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0043292 (contractile fiber), GO:0043229 (intracellular organelle), GO:0016528 (sarcoplasm), GO:0043228 (non-membrane-bounded organelle), GO:0098827 (endoplasmic reticulum subcompartment), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0099081 (supramolecular polymer), GO:0016529 (sarcoplasmic reticulum), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005789 (endoplasmic reticulum membrane), GO:0099512 (supramolecular fiber), GO:0030016 (myofibril), GO:0033017 (sarcoplasmic reticulum membrane)
Protein: Tat (Twin-arginine translocation) pathway signal sequence containing protein (O05446)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Not known
Sequence: MVTGQPAAAGAHSLSEGAMTAMQSGSVPPPQATPPITTPPVVSAPTMAAGIEATHGPVDTPANTSGAPPASTGTTGPVAPTVVTAGPVAAPAAPVVGGSAVPAGPLPAYGSDLRPPVVAAPAVPSVPTAPVSGAPVAPSASSAPSAGGALVSPVERAASKAVAGQAGASSSTMAGASALSATAGATAGAVSARAAEQQRLQRIVDAVARQEPRISWAAGLRDDGTTTLLVTDLAGGWIPPHVRLPANVTLLEPTARRRDADVIDLLGAVVAVAAHESNTYVAEPGPDAPALTGDRSARSAIPKVDEFGPTLVEAVRRRDSLPRIAQAIALPAVRKTGVLENEAELLHGCITAVKESVLKAYPSHELTAVGDWMLLAAIEALIDEQDYLANYHLAWYAVTTRRGGSRGFAA
InterPro domains: - IPR040604: Domain of unknown function DUF5632 (domain) [195-276]
- IPR040833: Domain of unknown function DUF5631 (domain) [304-397]
Interaction partners: - Conserved hypothetical alanine rich protein
- ESX-2 secretion system protein eccD2
- ESX-2 secretion system ATPase EccB2
- ESX conserved component EccC2. ESX-2 type VII secretion system protein. Possible membrane protein
- PE-PGRS family protein PE_PGRS16
- Methyltransferase domain-containing protein
- Protein-glutamine gamma-glutamyltransferase-like C-terminal domain-containing protein
- Uncharacterized protein Rv2067c
- PPE family protein PPE2
- Probable conserved proline, glycine, valine-rich secreted protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response), GO:0052553 (modulation by symbiont of host immune response), GO:0052559 (induction by symbiont of host immune response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Quick-to-court, isoform L (M9PCM5)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MANGKPRNLSLQLNGGSDISSSGTSSSSSNNKESSPRTTRTPRTPQTPQTPQTPASGVAASVAETPHSCIRQGNCVKANQVKLSTLHESKISPRTPPVTPDSPSTYLDDDIDSMYSFATTTSGRSTMSCEHPYVARNGTTFSGRKMKYVVHCSNYAGQVGPDYLTPTQRAQRQIRRLKELLCIARQDLEQKDTELLRLTREVVELRLFKASLSSPEERSASSDAVTVREAELKTSQDVSPIVDMVDEGNAKGSPRHLSRQQQQQANHSLQAMQMSAEMQSSYADSGHFEDLTMSSVHSKDSQTQSEACGTATPDGEADVGCGAGGDSASNLENYELQRQELISMYEHRIEELIRSQDSATSDLKRSHNDKVEALLQKLAECNTRYSDMVPDYEQAKQRIRELEKQLEDLQRKLIEHEEKQNKMYLHMYQQGQEAERISRADQALDLAQRQPESKVSINELLHQLQSTQDELENIRTIYRRLLEAQKNRTHVDPEVTLQFLKSAIFYFLTDKENSQGHLQAIESILEFTDAEKQKISAANRTPK
InterPro domains: - IPR000237: GRIP domain (domain) [490-538]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0051020 (GTPase binding), GO:0031267 (small GTPase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0019098 (reproductive behavior), GO:0032504 (multicellular organism reproduction), GO:0007610 (behavior), GO:0007617 (mating behavior), GO:0007619 (courtship behavior), GO:0060179 (male mating behavior), GO:0008049 (male courtship behavior)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098791 (Golgi apparatus subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0005802 (trans-Golgi network)
Protein: Trehalose-6-phosphate phosphatase (Trehalose-phosphatase) (Q059G6)
Organism: Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii)
Function: Not known
Sequence: MDSMHPDPTPEVPPSLPDLKAQVARLEASHKEKGLPLSGRIIHVMHHLPVEIVRIVPADALESAGTGFLSPPMTPEFKPEDAETTVESADAKWRIHARTAHPALVSGIKSLSETHDQLLVAWTGEVLIQPDNTQSPQQPSQATFSSIASNLLAPFSAGDATPQPQPPPQQGSLMVFGGEFNEADQKEIASELDRFAEAEAKFDPTDRLKYIPVFLPPDVSKGHYEGFCKKTLWPLFHYLLWLDSTATVPSPDPSWLAYQKTNQMFAQRVAQIYKPGDLIICHDYHLLLAPKMIRESLGQVFHPNAGWGTAHPSPSLHHAQRKGFDWESNQQTPTPEKAKGEKIGAFMNHVGTALGNHLGTMEHGLQNEIMIGMFMHTPWPSSEIFRCLPKRREILDGMLGANLVSFQTYSYSRHFVSTCIRVCGYESTPGGVDANGQVTAVGYCPIGIDIKRVVHDRDQPGVLPKMQALRDLYKDKKIIVGREKLDVAKGVYNKLQAFEKFLQVYPEWRGKVVLIQVTTPALSESPKLERMTAELVSHINGTYGSLDFTPVHHYHQALEKDEYFGLLSCADLALITSLRDGMNTTSMEFILCQDKTSKSPLVLSEFMGTAPSFASALQINPHDLLGVAQAINKGLTMRKEEKAERHANLLEGVLAHTSHTWAATILKQLLENVGGEHTAHHTPALDTAQFTDAYKKANKRLLLFDYDGTLTPIVKVPSHAVPTERTRNAIAALCKDPKNVVYLISGRDGDFLEEHWGHLDRLGLSAEHGSFVKQPGEEDFINMTEALDMSWMSEVEEIFKYYTERTTGSTIEVKKASITWHYRNSDPDFGEFQCKQALDLLESSLAPRRPIEVLVGKKNLEVRPLAVNKGEIVRRLMYENPDVDLIFCAGDDKTDEDMFRALRTIFPPGGVVDNNPVVMKPPVAVTSALEPEEVAELPDVELTIRSKGVFATTVGPPAKRTLAGWHVTCPEEVVEAFESLLEEIQVV
InterPro domains: - IPR006379: HAD-superfamily hydrolase, subfamily IIB (family) [701-905]
- IPR036412: HAD-like superfamily (homologous_superfamily) [700-981]
- IPR003337: Trehalose-phosphatase (family) [697-981]
- IPR023214: HAD superfamily (homologous_superfamily) [702-902]
- IPR001830: Glycosyl transferase, family 20 (family) [35-980]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0016791 (phosphatase activity), GO:0019203 (carbohydrate phosphatase activity), GO:0004805 (trehalose-phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0044249 (cellular biosynthetic process), GO:0005975 (carbohydrate metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044262 (cellular carbohydrate metabolic process), GO:0009311 (oligosaccharide metabolic process), GO:0005984 (disaccharide metabolic process), GO:0016051 (carbohydrate biosynthetic process), GO:0034637 (cellular carbohydrate biosynthetic process), GO:0005991 (trehalose metabolic process), GO:0009312 (oligosaccharide biosynthetic process), GO:0046351 (disaccharide biosynthetic process), GO:0005992 (trehalose biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:1990234 (transferase complex)
Protein: Zwilling (B9UZF4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Sequence: MGNTSFTEGKTALSVGGSSIARGKTSITMGKSSITRGVTTTSMGDSTITRGKTTISLGRASFSRGKTTTSIRKAFMPKRRTK
InterPro domains: - IPR011049: Serralysin-like metalloprotease, C-terminal (homologous_superfamily) [1-76]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016740 (transferase activity), GO:0140098 (catalytic activity, acting on RNA), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0097747 (RNA polymerase activity), GO:0016779 (nucleotidyltransferase activity), GO:0034062 (5'-3' RNA polymerase activity), GO:0003899 (DNA-directed 5'-3' RNA polymerase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0006397 (mRNA processing), GO:0016071 (mRNA metabolic process), GO:0031123 (RNA 3'-end processing), GO:0043631 (RNA polyadenylation), GO:0006378 (mRNA polyadenylation), GO:0031124 (mRNA 3'-end processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Myosin XIX (A0A087WU55)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MLQQVNGHNPGSDGQAREYLREDLQEFLGGEVLLYKLDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAPQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPASWESHKIAERIEQRILNSN
InterPro domains: - IPR036961: Kinesin motor domain superfamily (homologous_superfamily) [16-176]
- IPR001609: Myosin head, motor domain-like (domain) [35-176]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [30-176]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0051640 (organelle localization), GO:0071840 (cellular component organization or biogenesis), GO:0140352 (export from cell), GO:0051649 (establishment of localization in cell), GO:0016043 (cellular component organization), GO:0046907 (intracellular transport), GO:0051656 (establishment of organelle localization), GO:0006810 (transport), GO:0051647 (nucleus localization), GO:0007097 (nuclear migration), GO:0006996 (organelle organization), GO:0010256 (endomembrane system organization), GO:0061024 (membrane organization), GO:0006998 (nuclear envelope organization), GO:0006997 (nucleus organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Glyoxalase I-like protein GILP (EC 4.4.1.5) (C6KSP5)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Not known
Sequence: MKLFVVVIFVLFILLKRYKCLSKKKNRCHYFINRDSYHLKKKKCKRKILKCKVDGIEYKVHDLDKSINFYTNVLNFKVNKKEKDNAQLILGDDGAYIKLIQKGEGNFTIGEHSFLGLGVHLKNFDINKTKLYEGKIDEEIDKRPVTPCILPDEDAQVRRFWTNCFITDPDGYGIEVVLQNESDKLDRIRFFTTSTKDAQKFYSDILGMQLVKIQSHLEEISYPWNIYGGMSYYFSSENNSTILQMAYAYDEEELHMGNSLGNLILCSKNLNLIEKKLNENNIEVIKNDKGEILVKDLDGYNVYLKDK
InterPro domains: - IPR029068: Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase (homologous_superfamily) [52-307]
- IPR004360: Glyoxalase/fosfomycin resistance/dioxygenase domain (domain) [56-176]
- IPR037523: Vicinal oxygen chelate (VOC), core domain (domain) [52-179]
Interaction partners: - hydroxyacylglutathione hydrolase
- hydroxyacylglutathione hydrolase
- Lactoylglutathione lyase
- NADH-cytochrome b5 reductase, putative
- FAD-dependent monooxygenase, putative
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016840 (carbon-nitrogen lyase activity), GO:0016841 (ammonia-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0009056 (catabolic process), GO:0042180 (cellular ketone metabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:0044282 (small molecule catabolic process), GO:1901575 (organic substance catabolic process), GO:0006081 (cellular aldehyde metabolic process), GO:0044248 (cellular catabolic process), GO:0006082 (organic acid metabolic process), GO:0006089 (lactate metabolic process), GO:0042182 (ketone catabolic process), GO:0046185 (aldehyde catabolic process), GO:0009438 (methylglyoxal metabolic process), GO:0043436 (oxoacid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0051596 (methylglyoxal catabolic process), GO:0032787 (monocarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)