Protein: Protein trichome birefringence-like 33 (F4IH21)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable xylan acetyltransferase that plays a role in xylan acetylation and normal deposition of secondary cell walls. Required for 2-O-monoacetylation, 3-O-monoacetylation and 2,3-O-diacetylation of xylosyl residues in xylan. Required for the formation of 3-O-acetylated, 2-O-glucoronic acid-substituted xylosyl residues. May act as a bridging protein that binds pectin and other cell wall polysaccharides. Probably involved in maintaining esterification of pectins (By similarity).
Subcellular location: Golgi apparatus membrane {ECO:0000305|PubMed:26745802}; Single-pass type II membrane protein {ECO:0000255}.
Sequence: MKPSSPISLTSSSIARKARFSPYLFTLLAFILFVSVLYGEDFMCIFGQLEPNFVLPPSRTPEKNKKSEKLAFAIGKTEESCDVFSGKWVRDEVSRPLYEEWECPYIQPQLTCQEHGRPDKDYQFWRWQPNHCDLPSFNASLMLETLRGKRMMYVGDSLNRGMFVSMICLLHRLIPEDQKSIKTNGSLTVFTAKEYNATIEFYWAPFLLESNSDDAIVHRISDRVVRKGSINKHGRHWKGVDIIIFNTYLWWMTGLKMNILQGSFDDKEKNIVEVSTEDAYRMGMKSMLRWVKNNMDRKKTRVFFTSMSPTHAKGIDWGGEPGQNCYNQTTLIEDPSYWGSDCRKSIMKVIGEVFGRSKTPITLLNITQMSNYRKDAHTSIYKKQWSPLTAEQLENPTSYADCVHWCLPGLQDTWNELLFAKLFYT
InterPro domains: - IPR029962: Trichome birefringence-like family (family) [35-419]
- IPR025846: Trichome birefringence-like, N-terminal domain (domain) [79-133]
- IPR026057: Trichome birefringence-like, C-terminal domain (domain) [134-420]
Interaction partners: - Glucuronoxylan 4-O-methyltransferase 1
- Protein REDUCED WALL ACETYLATION 2
- UDP-glucuronate:xylan alpha-glucuronosyltransferase 1
- Protein SODIUM POTASSIUM ROOT DEFECTIVE 2
- UDP-glucuronate:xylan alpha-glucuronosyltransferase 2
- Protein REDUCED WALL ACETYLATION 3
- Beta-1,4-xylosyltransferase IRX9
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0008374 (O-acyltransferase activity), GO:0016407 (acetyltransferase activity), GO:0016413 (O-acetyltransferase activity), GO:1990538 (xylan O-acetyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071554 (cell wall organization or biogenesis), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0044036 (cell wall macromolecule metabolic process), GO:0044085 (cellular component biogenesis), GO:1901576 (organic substance biosynthetic process), GO:0042546 (cell wall biogenesis), GO:0044249 (cellular biosynthetic process), GO:0005975 (carbohydrate metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0044262 (cellular carbohydrate metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:0070589 (cellular component macromolecule biosynthetic process), GO:0016051 (carbohydrate biosynthetic process), GO:0005976 (polysaccharide metabolic process), GO:0034637 (cellular carbohydrate biosynthetic process), GO:0010383 (cell wall polysaccharide metabolic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:0044038 (cell wall macromolecule biosynthetic process), GO:0044264 (cellular polysaccharide metabolic process), GO:0033692 (cellular polysaccharide biosynthetic process), GO:0000271 (polysaccharide biosynthetic process), GO:0070592 (cell wall polysaccharide biosynthetic process), GO:0010410 (hemicellulose metabolic process), GO:0045491 (xylan metabolic process), GO:0045492 (xylan biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)