Protein: RNA helicase (EC 3.6.4.13) (Q9V3C4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MEREIAHSLAGGEERSSDVAPGQVKTFEELRLYRNLLNGLKRNNFVTPTKIQAAAIPMALAKMDLIIQSKSGTGKTLIYVIAVVQSFNPNINQPHAMIVVPTRELAIQVQDTFFHLCKSFRDFKCSAFIGGTDVAKDRKRMNESRVIIGTPGRLLHLYENRVFDVSKLRLLVLDEADQLYQTKSLQHTVSKLIEAMPKNRQIIACSATYDQNLDERLAKVMDKPMLISNSERATVLLGIRQFVYELPQQNNSVEEMRLKLQILGQIFNQLPYEQAIIFASSQMRADSYKNYLTASGIDCHLISGAMEQSERLHVFEGYRNFTMRILVATDLMARGVDSPHANLVINIDPPQDHVTYLHRIGRAGRFGSKGIAITFIASKKESQRFREMSKKIATAWSVLEFPKEPMPNEFNFWDFEKYNFDYYIKEENPLQEMPMPIKENRSKENVDASSVDLENLQKDQDGKRRDPDKLPVALENVETQKELELENLPESSHNNKNLRVKEKEIVRQGKLKETNSKAGGSKTNKTERRKKSNTPSKLQKQITEVQQTPEITVNKYYMQEDIQRTADGKEYHPVNGAGNHQVPSKSNQKPVEFISPELTPTLTPLELTQEPSPTTVTPPAPPANSINNKTYCLAAPTQTSSMTIQNMVISNTVDDASSISSDSMVVCGYHSDRSYDTYYATSDEEEIWNRLMSKQRRQLKSKRGHGKRRVILYKKVFPKLKANVKRKLKKRMSSSCRSKKAHHLRKRHVYKNISLLPHMNLCHLLQKFTNQERFLKRLHKYAKNQFIDNARVGFLLDKLYKSILEMYYNSAKERKKHFKEAMKESLKSIDNYESQESSESEEEEEEEKDLKNKLSVHVTNQMDIPPMPQAAVEIGSGSESDTEDSQEYGEGEEIIVDDEDDGSDGGPNSSSGFVESQESVSSGIDTSVYETESTGASGNNSSAFFISDDESDTESLTDSEAGSNVSATGSSSQRSSVASSTYESSDDDSVTVTNVSSMQNAQSLWLQTFNMQYQFIASHVAKNLQNYY
InterPro domains: - IPR050079: DEAD box RNA helicase (family) [18-546]
- IPR014014: RNA helicase, DEAD-box type, Q motif (domain) [25-53]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [9-402]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [44-242]
- IPR011545: DEAD/DEAH-box helicase domain (domain) [49-215]
- IPR001650: Helicase, C-terminal domain-like (domain) [238-407]
Interaction partners: - Gem-associated protein 5
- Survival motor neuron protein
- Serine-threonine kinase receptor-associated protein
- Gem-associated protein 4a
- Gem-associated protein 2
- Enhancer of mRNA-decapping protein 3
- GH10889p
- Lsm10
- FI05704p
- U6 snRNA-associated Sm-like protein LSm1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0019222 (regulation of metabolic process), GO:0007389 (pattern specification process), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0009892 (negative regulation of metabolic process), GO:0044237 (cellular metabolic process), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0048523 (negative regulation of cellular process), GO:0048609 (multicellular organismal reproductive process), GO:0044238 (primary metabolic process), GO:0007276 (gamete generation), GO:0007281 (germ cell development), GO:0007279 (pole cell formation), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0007349 (cellularization), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0046483 (heterocycle metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0043170 (macromolecule metabolic process), GO:0009880 (embryonic pattern specification), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0003002 (regionalization), GO:0046843 (dorsal appendage formation), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0016043 (cellular component organization), GO:0009790 (embryo development), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0080090 (regulation of primary metabolic process), GO:0035282 (segmentation), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0051246 (regulation of protein metabolic process), GO:0051248 (negative regulation of protein metabolic process), GO:0048477 (oogenesis), GO:0006325 (chromatin organization), GO:0010628 (positive regulation of gene expression), GO:0010468 (regulation of gene expression), GO:0022607 (cellular component assembly), GO:0034248 (regulation of amide metabolic process), GO:0007292 (female gamete generation), GO:0090304 (nucleic acid metabolic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0000578 (embryonic axis specification), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0051252 (regulation of RNA metabolic process), GO:0006996 (organelle organization), GO:0051253 (negative regulation of RNA metabolic process), GO:0007351 (tripartite regional subdivision), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:0010629 (negative regulation of gene expression), GO:0009952 (anterior/posterior pattern specification), GO:0034249 (negative regulation of amide metabolic process), GO:0070925 (organelle assembly), GO:0017148 (negative regulation of translation), GO:0016070 (RNA metabolic process), GO:0001700 (embryonic development via the syncytial blastoderm), GO:0061014 (positive regulation of mRNA catabolic process), GO:0016441 (post-transcriptional gene silencing), GO:0031047 (RNA-mediated gene silencing), GO:0006396 (RNA processing), GO:0040029 (epigenetic regulation of gene expression), GO:0006338 (chromatin remodeling), GO:0045814 (negative regulation of gene expression, epigenetic), GO:2000112 (regulation of cellular macromolecule biosynthetic process), GO:0006417 (regulation of translation), GO:1903311 (regulation of mRNA metabolic process), GO:2000113 (negative regulation of cellular macromolecule biosynthetic process), GO:0010608 (post-transcriptional regulation of gene expression), GO:0031048 (RNA-mediated heterochromatin formation), GO:0034470 (ncRNA processing), GO:0031507 (heterochromatin formation), GO:0034508 (centromere complex assembly), GO:0070828 (heterochromatin organization), GO:1903507 (negative regulation of nucleic acid-templated transcription), GO:0140694 (non-membrane-bounded organelle assembly), GO:0034660 (ncRNA metabolic process), GO:0080188 (gene silencing by RNA-directed DNA methylation), GO:0140718 (facultative heterochromatin formation), GO:0030422 (siRNA processing), GO:0035195 (miRNA-mediated gene silencing), GO:0006346 (DNA methylation-dependent heterochromatin formation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0035770 (ribonucleoprotein granule), GO:0036464 (cytoplasmic ribonucleoprotein granule), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0045495 (pole plasm), GO:0043228 (non-membrane-bounded organelle), GO:0043186 (P granule), GO:0060293 (germ plasm), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005634 (nucleus)