Protein: Hemoglobin subunit delta (Delta-globin) (Hemoglobin delta chain) (P02042)
Organism: Homo sapiens (Human)
Function: Involved in oxygen transport from the lung to the various peripheral tissues.
Sequence: MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARNFGKEFTPQMQAAYQKVVAGVANALAHKYH
InterPro domains: - IPR050056: Hemoglobin and related oxygen transporters (family) [1-147]
- IPR012292: Globin/Protoglobin (homologous_superfamily) [2-147]
- IPR000971: Globin (domain) [3-147]
- IPR002337: Hemoglobin, beta-type (family) [8-146]
- IPR009050: Globin-like superfamily (homologous_superfamily) [2-147]
Interaction partners: - Hemoglobin subunit alpha
- Alpha-hemoglobin-stabilizing protein
- Hemoglobin subunit theta-1
- Hemoglobin subunit zeta
- Hemoglobin subunit mu
- Hemoglobin subunit beta
- Hemoglobin subunit gamma 1
- Hemoglobin subunit gamma-2
- 5-aminolevulinate synthase, erythroid-specific, mitochondrial
- Protein 4.2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016209 (antioxidant activity), GO:0004601 (peroxidase activity), GO:0036094 (small molecule binding), GO:0016491 (oxidoreductase activity), GO:0005515 (protein binding), GO:0019825 (oxygen binding), GO:0016684 (oxidoreductase activity, acting on peroxide as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0065008 (regulation of biological quality), GO:0001775 (cell activation), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0007155 (cell adhesion), GO:0050794 (regulation of cellular process), GO:0050817 (coagulation), GO:0051234 (establishment of localization), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0003008 (system process), GO:0048522 (positive regulation of cellular process), GO:0030168 (platelet activation), GO:0010942 (positive regulation of cell death), GO:0010035 (response to inorganic substance), GO:0050878 (regulation of body fluid levels), GO:0007596 (blood coagulation), GO:0010941 (regulation of cell death), GO:0009611 (response to wounding), GO:0098609 (cell-cell adhesion), GO:0072593 (reactive oxygen species metabolic process), GO:0006979 (response to oxidative stress), GO:0044248 (cellular catabolic process), GO:0006810 (transport), GO:0003014 (renal system process), GO:0042743 (hydrogen peroxide metabolic process), GO:1901700 (response to oxygen-containing compound), GO:1901575 (organic substance catabolic process), GO:0010033 (response to organic substance), GO:0042060 (wound healing), GO:0071705 (nitrogen compound transport), GO:0034109 (homotypic cell-cell adhesion), GO:0042744 (hydrogen peroxide catabolic process), GO:0070527 (platelet aggregation), GO:0070293 (renal absorption), GO:0015669 (gas transport), GO:0042542 (response to hydrogen peroxide), GO:0007599 (hemostasis), GO:0000302 (response to reactive oxygen species), GO:0015671 (oxygen transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005833 (hemoglobin complex), GO:0005829 (cytosol), GO:0072562 (blood microparticle), GO:0005615 (extracellular space), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0012505 (endomembrane system), GO:0005576 (extracellular region), GO:0030141 (secretory granule), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043230 (extracellular organelle), GO:0043233 (organelle lumen), GO:0070062 (extracellular exosome), GO:0043227 (membrane-bounded organelle), GO:0101002 (ficolin-1-rich granule), GO:0030139 (endocytic vesicle), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0070820 (tertiary granule), GO:0070013 (intracellular organelle lumen), GO:0031982 (vesicle), GO:0071682 (endocytic vesicle lumen), GO:1904813 (ficolin-1-rich granule lumen), GO:1903561 (extracellular vesicle), GO:0097708 (intracellular vesicle), GO:1904724 (tertiary granule lumen)