Protein: Neuronal growth regulator 1 (Kindred of IgLON) (Kilon) (Q9Z0J8)
Organism: Rattus norvegicus (Rat)
Function: May be involved in cell-adhesion. May function as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain (By similarity).
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor.
Sequence: MVLLAQGACCSNQWLAAVLLSLCSCLPAGQSVDFPWAAVDNMLVRKGDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTINEGTNVTLTCLATGKPEPAISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVKKVRVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKRLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPSTAQYGITGSACDLFSCWSLALTLSSVISIFYLKNAILQ
InterPro domains: - IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [40-306]
- IPR013098: Immunoglobulin I-set (domain) [40-129]
- IPR007110: Immunoglobulin-like domain (domain) [27-307]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [36-306]
- IPR003598: Immunoglobulin subtype 2 (domain) [45-298]
- IPR003599: Immunoglobulin domain subtype (domain) [39-309]
- IPR050876: IgLON domain-containing protein (family) [38-307]
Interaction partners: - Transmembrane protein 18
- Glucosamine-6-phosphate isomerase
- IgLON family member 5
- Mitochondrial carrier 2
- Kctd15 protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048522 (positive regulation of cellular process), GO:0007155 (cell adhesion), GO:0050794 (regulation of cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0007610 (behavior), GO:0098609 (cell-cell adhesion), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0007631 (feeding behavior), GO:0016043 (cellular component organization), GO:0051130 (positive regulation of cellular component organization), GO:0051128 (regulation of cellular component organization), GO:0007626 (locomotory behavior), GO:0022008 (neurogenesis), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0031344 (regulation of cell projection organization), GO:0031346 (positive regulation of cell projection organization), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0010976 (positive regulation of neuron projection development), GO:0120036 (plasma membrane bounded cell projection organization), GO:0010975 (regulation of neuron projection development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)