Protein: Glycerate kinase (EC 2.7.1.31) (Q8QZY2)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q8IVS8}.
Sequence: MAAALQVLPCLLRAPSRPLLWGPPVARMTSGMALAEQARQLFDSAVGAVQPGPMLQRTLSLDPSGRQLKVRDRTFQLRENLYLVGFGKAVLGMAAAAEELLAQHLVQGVISVPKGIRAAMEHAGKKEMLLKPHSRVQVFEGAEDNLPDRDALRAALTIQQLAEGLTADDLLLVLISGGGSALLPAPIPPVTLEEKQMLTKLLAARGATIQELNTIRKALSQLKGGGLAQAAYPAQVISLILSDVIGDPLEVIASGPTVASAHSVQDCLHILNHYGLRAALPRSVKTVLSRADSDPHGPHTCGHVLNVIIGSNSLALAEAQRQAEVLGYHAMVLSTAMQGDVKRVARFYGLLARVAAAHLTPSLAERPLEEEAELHQLAAELQLPDLQLEEALEAVAKAKGPVCLLAGGEPTVQLQGSGKGGRNQELALHVGVELGRQPLGPIDVLFLSGGTDGQDGPTKVAGAWVMSDLISQASAESLDIATSLTNNDSYTFFCRFRGGTHLLHTGLTGTNVMDVHLLILHPQ
InterPro domains: - IPR007835: MOFRL domain (domain) [402-514]
- IPR037035: Glycerate kinase-like, C-terminal domain superfamily (homologous_superfamily) [306-523]
- IPR038614: Glycerate kinase, N-terminal domain superfamily (homologous_superfamily) [51-305]
- IPR025286: MOFRL-associated domain (domain) [38-288]
- IPR039760: MOFRL domain-containing protein (family) [27-521]
Interaction partners: - Glyoxylate reductase/hydroxypyruvate reductase
- 4-trimethylaminobutyraldehyde dehydrogenase
- Phosphoglycerate mutase 1
- Bisphosphoglycerate mutase
- Aldehyde dehydrogenase X, mitochondrial
- Aldehyde dehydrogenase, mitochondrial
- Aldehyde dehydrogenase family 3 member A2
- Alpha-aminoadipic semialdehyde dehydrogenase
- Phosphoglycerate mutase 2
- Pyruvate kinase PKLR
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044282 (small molecule catabolic process), GO:0019538 (protein metabolic process), GO:0019637 (organophosphate metabolic process), GO:0005996 (monosaccharide metabolic process), GO:0005975 (carbohydrate metabolic process), GO:1901575 (organic substance catabolic process), GO:0043170 (macromolecule metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0006081 (cellular aldehyde metabolic process), GO:0006793 (phosphorus metabolic process), GO:0036211 (protein modification process), GO:0019318 (hexose metabolic process), GO:0043412 (macromolecule modification), GO:0046365 (monosaccharide catabolic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0019682 (glyceraldehyde-3-phosphate metabolic process), GO:0016052 (carbohydrate catabolic process), GO:0019320 (hexose catabolic process), GO:0006468 (protein phosphorylation), GO:0006000 (fructose metabolic process), GO:0016310 (phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)