Protein: Calcium-dependent secretion activator (H9G2V2)
Organism: Caenorhabditis elegans
Function: Not known
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000256|ARBA:ARBA00004156}. Synapse {ECO:0000256|ARBA:ARBA00034103}.
Sequence: MLGASSSEEEDDDFQEDHDSLPIAQVKKRSLLSGAMTPRSSSPAPSDSVSQTNSLKRNNSSSQGRRKDSVQSQTPARSARIMSNVSKPIMQNSQEFDGDEEEGEEGSTTVVGSGDECGGPALSKEEQERMKAEREEEDHKKNLQMYMFLARCIAYPFNGQQTGDMARRQMKVNKQELARIRERFTLFLKGETNIAADEAFTKAIQSYFEVFLKSERVQKVVHAGGFSQHDFREVFRLNIEKRVRSLPDIEGLSKDTVLNSWLAKFDAIIKGDETDQNRNARGRSRNPQNAMSADAVLGKEQLYDVFQQILGVKKFEHQIIFNALQLDNPDEQAAAIRREFATREEALKDPIKMKRLTPKFVVKDMETLYMDEVRMSINTLIGNLETVPVTTRGATVGKRKDKSRNQTKNKRSRSIEDLSLFNSLKRRTSSGSLNKGDSEDGDVTLTKSDVSLALSMEVVVMEVQGLKSVQPSKIVYCTMEVDGHKLQTDHAEASKPKWDTQGDFSTKNPLPVVKVKLYTEVKSMIAFEDKELGKVIIQPTPNCARSPEWYTMTLPKSSQDQNLKIRIAIRVEKPPNLKYCGYCYCIGRNAWKKWKKRFFCLVQVSQYAFAVCSFRQKKADPTEFIQLDGFTIDYMPESDPELSAQGGKHFFTAIKEGDELKFATDDENERHLWVQALYRATGQAYKPVPPKQSTIAPKAQGFQDKASKHGMDAMIQADSINFDHDHFYSDVQRLTLDFRINEPICSLGWFSPGQAFVLEEYSARYMVRGCFRHVTLLSNLLDKADDGLLIDPALIHYSFAFCASHVHGNRCMPDRQGPEGVGTVTLEEKEKFQEIKERLRVLLEKQITNFRYCFPFGRPEGALKGTLGLLERVLMKDVVSPVPPEEVRAVIRKCLEDAALVNYTRICNEAKIEQRMGIDVSPAQRIEDMIRVTEFCIDLLKENEEHHGEAFAWFSDLLSDHSEIFWSLYSVDLDSALEVQPHDSWDSFPLFQMLNDFLLSESSLKGGIFHNKIVQQFQPLVVRYIDLMEHSIAQAIDKGFSKEKWESRKEGCATSEDIYWKLDALHTFVIDLNWPEEDFRKYLQTKMKSLTSDMISKVSDCTFTAFDSWMQRAKKSTDYMLPSEVCVQINVMFSSKSRAVRVTVDSGEYKYQSKLDETLETMLKTMESCIQEKLHGVLESVLSRLARYDEGNPIGAILNIAPKPASIFNKLKTMAGDTSAQATTTARQPLTAQQSSGQIGNSYVTFFHGCTELLRQVIIDEIWVNGLFEHWYDNQMKSINEWLTERLQQSLSATQYISLSTIVKKVYQDFSLQGIDEERLNSKTYQSISRRLQLEESNSHIQEAAINGSAQGSVFPTSLGNATAAVSNMSSMVEGAGAKMFSLFK
InterPro domains: - IPR035892: C2 domain superfamily (homologous_superfamily) [454-572]
- IPR001849: Pleckstrin homology domain (domain) [576-684]
- IPR014770: Munc13 homology 1 (domain) [971-1102]
- IPR057457: CAPS, C2 domain (domain) [475-573]
- IPR000008: C2 domain (domain) [437-554]
- IPR010439: MUN domain (domain) [888-1263]
- IPR033227: Calcium-dependent secretion activator (family) [1-1345]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [576-689]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0023052 (signaling), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0051641 (cellular localization), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0042221 (response to chemical), GO:0051234 (establishment of localization), GO:0051241 (negative regulation of multicellular organismal process), GO:0051239 (regulation of multicellular organismal process), GO:0032504 (multicellular organism reproduction), GO:0007267 (cell-cell signaling), GO:0065008 (regulation of biological quality), GO:0019098 (reproductive behavior), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051716 (cellular response to stimulus), GO:0140352 (export from cell), GO:0007154 (cell communication), GO:0040012 (regulation of locomotion), GO:0007610 (behavior), GO:0048522 (positive regulation of cellular process), GO:0050920 (regulation of chemotaxis), GO:0048731 (system development), GO:0044057 (regulation of system process), GO:0048513 (animal organ development), GO:0018991 (oviposition), GO:0007631 (feeding behavior), GO:0051649 (establishment of localization in cell), GO:0032101 (regulation of response to external stimulus), GO:0001505 (regulation of neurotransmitter levels), GO:1901700 (response to oxygen-containing compound), GO:0051130 (positive regulation of cellular component organization), GO:0090325 (regulation of locomotion involved in locomotory behavior), GO:0030537 (larval behavior), GO:0010033 (response to organic substance), GO:0048521 (negative regulation of behavior), GO:0007626 (locomotory behavior), GO:0010035 (response to inorganic substance), GO:0099536 (synaptic signaling), GO:0007635 (chemosensory behavior), GO:0070887 (cellular response to chemical stimulus), GO:0006810 (transport), GO:0032940 (secretion by cell), GO:0051128 (regulation of cellular component organization), GO:0050795 (regulation of behavior), GO:0023061 (signal release), GO:1902074 (response to salt), GO:0007419 (ventral cord development), GO:0071705 (nitrogen compound transport), GO:0031344 (regulation of cell projection organization), GO:0010037 (response to carbon dioxide), GO:1902075 (cellular response to salt), GO:0071702 (organic substance transport), GO:0046903 (secretion), GO:0090257 (regulation of muscle system process), GO:1902667 (regulation of axon guidance), GO:0006836 (neurotransmitter transport), GO:0099504 (synaptic vesicle cycle), GO:0006887 (exocytosis), GO:0007399 (nervous system development), GO:0031346 (positive regulation of cell projection organization), GO:0071241 (cellular response to inorganic substance), GO:0099643 (signal release from synapse), GO:0030536 (larval feeding behavior), GO:0099537 (trans-synaptic signaling), GO:2000252 (negative regulation of feeding behavior), GO:0060259 (regulation of feeding behavior), GO:0007417 (central nervous system development), GO:0007269 (neurotransmitter secretion), GO:0016192 (vesicle-mediated transport), GO:1901701 (cellular response to oxygen-containing compound), GO:0016079 (synaptic vesicle exocytosis), GO:0048791 (calcium ion-regulated exocytosis of neurotransmitter), GO:0006937 (regulation of muscle contraction), GO:0015850 (organic hydroxy compound transport), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0010976 (positive regulation of neuron projection development), GO:0015844 (monoamine transport), GO:0098916 (anterograde trans-synaptic signaling), GO:0099003 (vesicle-mediated transport in synapse), GO:1902669 (positive regulation of axon guidance), GO:1903998 (regulation of eating behavior), GO:0071244 (cellular response to carbon dioxide), GO:0045055 (regulated exocytosis), GO:0007268 (chemical synaptic transmission), GO:0017156 (calcium-ion regulated exocytosis), GO:0006837 (serotonin transport), GO:0043051 (regulation of pharyngeal pumping), GO:0010975 (regulation of neuron projection development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0044297 (cell body), GO:0036477 (somatodendritic compartment), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0030054 (cell junction), GO:0043025 (neuronal cell body), GO:0030141 (secretory granule), GO:0120025 (plasma membrane bounded cell projection), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0043227 (membrane-bounded organelle), GO:0043005 (neuron projection), GO:0099503 (secretory vesicle), GO:0031045 (dense core granule), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0030424 (axon), GO:0097708 (intracellular vesicle)