wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Tetratricopeptide repeat protein 23 (TPR repeat protein 23) (Cervical cancer proto-oncogene 8 protein) (HCC-8) (Q5W5X9)
Organism: Homo sapiens (Human)
Function: Participates positively in the ciliary Hedgehog (Hh) signaling.
Subcellular location: Cell projection, cilium {ECO:0000250|UniProtKB:Q8CHY7}. Note=Colocalizes with EVC and IQCE at the EvC zone of primary cilia. {ECO:0000250|UniProtKB:Q8CHY7}.
Sequence: MQESQETHISNHLDEVVAAVSITHRKKFQNKLLQTALFQPPREKLHLCEEKAKSYSNSHEYKQAVHELVRCVALTRICYGDSHWKLAEAHVNLAQGYLQLKGLSLQAKQHAEKARQILANSIVPPYSENTDVFKFSIELFHTMGRALLSLQKFKEAAENLTKAERLSKELLQCGRIIKEEWIEIEARIRLSFAQVYQGQKKSKEALSHYQAALEYVEISKGETSRECVPILRELAGVEQALGLHDVSINHFLQAHLIILSRSPSQVEAADSAHIVAHAAVASGRHEHHDVAEQYFQESMAHLKDSEGMGRTKFLSIQDEFCHFLQMTGQKERATSILRESLEAKVEAFGDFSPEVAETYRLLGGADLAQGNHSGARKKLKKCLQIQTLLYGPQDKRTLATQQAMGMLSTAPKVASKPRQASKAKVAFCTSIPQDTLLGKARPGTTAD
InterPro domains: - IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [26-424]
- IPR042621: Tetratricopeptide repeat protein TTC23/TTC23L (family) [2-436]
- IPR019734: Tetratricopeptide repeat (repeat) [87-389]
Interaction partners: - IQ domain-containing protein E
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023056 (positive regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010647 (positive regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0010646 (regulation of cell communication), GO:0045880 (positive regulation of smoothened signaling pathway), GO:0008589 (regulation of smoothened signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0042995 (cell projection), GO:0043226 (organelle), GO:0120025 (plasma membrane bounded cell projection), GO:0043227 (membrane-bounded organelle), GO:0005929 (cilium)
Protein: MGT2 magnesium transporter (Q57XY6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MPCATKGEASPPVTTPVGRDGCLCVVTWQTAGRMSLQTCALESAADALVFLRNNLPGIALCGLWVDMQKCSEEEHRQVLQLLYPNMQPSHVEAVLANDMYDVVELQPTEGEYVVGCLSCSPSHGGPFPAATAMSRTELGCEEGVLCSFVCSERVLLTLHTAPFAGLAELFRHVLKCNGSEAERHSRECEDSVVGIVKDPSSHRSSFVPVAMGTDALCTLVCFTCEASFPAPASLLSEVGDINEMVFLISPGEQDQTDLLRRVALLRRRISSFRTALFLKEKLIHQLISPAMRLTFVSKSHPSAVAYKEILARVQKVSEKLDDARDMLNHANLNFITGVSMRMSQASAGLDFKMNILNSVAAVSLPINLVVSLFGMNLKVPFMTGEGSTLIPFWTICAVFVVWAGICLTPLFRRAQRGLKNDPIAPYE
InterPro domains: - IPR044089: Magnesium transporter Alr1-like (family) [64-413]
- IPR045863: CorA, transmembrane region (homologous_superfamily) [351-412]
- IPR045861: CorA, cytoplasmic domain (homologous_superfamily) [62-329]
- IPR002523: Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB (family) [236-406]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0046873 (metal ion transmembrane transporter activity), GO:0015095 (magnesium ion transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0006811 (monoatomic ion transport), GO:0006812 (monoatomic cation transport), GO:0030001 (metal ion transport), GO:0015693 (magnesium ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Rifin (Q8IM84)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Not known
Sequence: MKVHYINILLFAFPLNILVNTHKKPSITPHHTPKIPTTRLLCECELFEPANYDSDPQMRAVMDNFSKQTQQRFHEYDESLQSKRMQCKDKCDKEIQKIILKDKLEKQMKQELTTLETKITTDDIPTCICEKSVADKMEKGCLRCAGVFSGGVAPSVGLLGGIGVYGWKMGAPTVAMELAKQAGIEEGVKTVIAQIKGISIFNPYLESVECSKYITKLNYDNVSGLMKAVQAAIKSTGETCEANSGDIVCETIYNKVERFLPVVQAGKQATTTTTETVKNAALDTIESTATTCTTAITASIIAIVVIVLIMVIIYKILRYRRKKKMKKKLQYIKLLEE
InterPro domains: - IPR006373: Variant surface antigen Rifin (family) [1-337]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response), GO:0042783 (evasion of host immune response), GO:0020033 (antigenic variation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0033643 (host cell part), GO:0043657 (host cell), GO:0033644 (host cell membrane), GO:0020002 (host cell plasma membrane)
Protein: Regulator of G-protein signaling rgs-2 (P49808)
Organism: Caenorhabditis elegans
Function: Weakly inhibits G protein signaling in nervous system, interacting preferentially with the G(O) subfamily member goa-1. In vitro, it acts as a GTPase activator of goa-1. Rgs-1 and rgs-2 redundantly adjust signaling when worms are fed to allow rapid induction of egg-laying behavior. Modulates chemotaxis responses by regulating negatively the sensitivity to quinine in ASH sensory neurons.
Sequence: MRLLTCDCTFMGQKHSGSVSVEKKNQENDGPPTYEIVFGWSQSFENLMKHRAGQKYFAEFLKGEYSDENILFWQACEELKREKNAEKIEEKARIIYEDFISILSPKEVSLDSRVREIVNTNMGRPSASTFDEAQNQIYTLMQRDSYPRFLASNIYKTVMGTFGIKEEAV
InterPro domains: - IPR044926: RGS, subdomain 2 (homologous_superfamily) [65-144]
- IPR024066: RGS, subdomain 1/3 (homologous_superfamily) [39-158]
- IPR036305: RGS domain superfamily (homologous_superfamily) [37-160]
- IPR016137: RGS domain (domain) [40-159]
Interaction partners: - Regulator of G-protein signaling rgs-11
- Guanine nucleotide-binding protein subunit alpha
- Guanine nucleotide-binding protein alpha-5 subunit
- Guanine nucleotide-binding protein subunit beta-2
- Guanine nucleotide-binding protein subunit beta-1
- Guanine nucleotide-binding protein alpha-16 subunit
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0008047 (enzyme activator activity), GO:0060589 (nucleoside-triphosphatase regulator activity), GO:0030695 (GTPase regulator activity), GO:0005096 (GTPase activator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0003008 (system process), GO:0007610 (behavior), GO:0042221 (response to chemical), GO:0007635 (chemosensory behavior), GO:0050877 (nervous system process), GO:0007600 (sensory perception), GO:0007606 (sensory perception of chemical stimulus), GO:0050909 (sensory perception of taste), GO:0050913 (sensory perception of bitter taste)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: C4-dicarboxylic acid transporter DauA (Dicarboxylic acid uptake system A) (P0AFR2)
Organism: Escherichia coli (strain K12)
Function: Responsible for the aerobic transport of succinate from the periplasm to the cytoplasm at acidic pH. Can transport other C4-dicarboxylic acids such as aspartate and fumarate. May also play a role in the regulation of C4-dicarboxylic acid metabolism at pH 7, via regulation of expression and/or activity of DctA. May act as a co-sensor of DcuS.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996, ECO:0000269|PubMed:23278959}; Multi-pass membrane protein {ECO:0000255}.
Sequence: MNKIFSSHVMPFRALIDACWKEKYTAARFTRDLIAGITVGIIAIPLAMALAIGSGVAPQYGLYTAAVAGIVIALTGGSRFSVSGPTAAFVVILYPVSQQFGLAGLLVATLLSGIFLILMGLARFGRLIEYIPVSVTLGFTSGIGITIGTMQIKDFLGLQMAHVPEHYLQKVGALFMALPTINVGDAAIGIVTLGILVFWPRLGIRLPGHLPALLAGCAVMGIVNLLGGHVATIGSQFHYVLADGSQGNGIPQLLPQLVLPWDLPNSEFTLTWDSIRTLLPAAFSMAMLGAIESLLCAVVLDGMTGTKHKANSELVGQGLGNIIAPFFGGITATAAIARSAANVRAGATSPISAVIHSILVILALLVLAPLLSWLPLSAMAALLLMVAWNMSEAHKVVDLLRHAPKDDIIVMLLCMSLTVLFDMVIAISVGIVLASLLFMRRIARMTRLAPVVVDVPDDVLVLRVIGPLFFAAAEGLFTDLESRLEGKRIVILKWDAVPVLDAGGLDAFQRFVKRLPEGCELRVCNVEFQPLRTMARAGIQPIPGRLAFFPNRRAAMADL
InterPro domains: - IPR036513: STAS domain superfamily (homologous_superfamily) [442-559]
- IPR018045: Sulphate anion transporter, conserved site (conserved_site) [58-79]
- IPR011547: SLC26A/SulP transporter domain (domain) [29-411]
- IPR002645: STAS domain (domain) [449-559]
- IPR001902: SLC26A/SulP transporter (family) [18-555]
Interaction partners: - Carbonic anhydrase 1
- Acyl carrier protein
- Carbonic anhydrase 2
- Putative ankyrin repeat protein YahD
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901682 (sulfur compound transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015116 (sulfate transmembrane transporter activity), GO:0015103 (inorganic anion transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0098739 (import across plasma membrane), GO:0006810 (transport), GO:0072530 (purine-containing compound transmembrane transport), GO:0071702 (organic substance transport), GO:0098657 (import into cell), GO:0071705 (nitrogen compound transport), GO:0015851 (nucleobase transport), GO:0006863 (purine nucleobase transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Protein ARABIDILLO 2 (Q9M224)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Promotes lateral root initiation and development, independently of auxin (IAA) and abscisis acid (ABA).
Subcellular location: Nucleus {ECO:0000269|PubMed:16434475}.
Sequence: MSRRVRQRVEDNGKYKVDSPSYTVIGVEDLAPKVQQYVNWTSLPYDTVFHLFTRLNYRDRASLASTCRTWRSLGASSFLWSSLDLRAHKFDLSMAASLATRCVDLQKIRFRGVDSADAIIHLKARSLLEISGDYCRKITDATLSMIAARHEALESLQLGPDFCERITSDAIRVIAFCCPKLKKLRVSGMRDVSSEAIESLAKHCPQLSDLGFLDCLNINEEALGKVVSLRYLSVAGTSNIKWKVALENWEKLPKLIGLDVSRTTIDHIAVSRLLKSSQSLKVLCALNCPYLEEDKSYSSNRFKGKVLLAVFTDTFDELASIFADNSKKPKNIFSYWRDLIRKDKSIDEIMLWIEWIISHTLLRIAESSNSQGLNDFWLNQGATLLLSLMQSAQEDVQERAATGLATFIVVDDENASIDCGRAEAVMRDGGIRLLLELAKSWREGLQSEAAKAIANLSVNAKVAKAVAEEGGISVLADLAKSMNRLVAEEAAGGLWNLSVGEEHKNAIAQAGGVNALVDLIFRWPHGCDGVLERAAGALANLAADDKCSMEVARAGGVHALVMLARNCKYEGAQEQAARALANLAAHGDSNGNNAAVGQEAGALEALVQLTQSPHEGVKQEAAGALWNLAFDDKNRESIAAFGGVEALVALAKSSSNASTGLQERVAGALWGLSVSEANSIAIGHEGGIPPLIALVRSEAEDVHETAAGALWNLSFNPGNALRIVEEGGVVALVQLCSSSVSKMARFMAALALAYMFDGRMDEYAMIGTSLESTSKSVTLNGARTMALDQIKAFIKTFMEHQIFSTGALSSAPSMLAQVSERARIPEAGHLRCSGSEIGRFVTMLRNPCLVLRACAAFALLQFTIPESRHAMHHASLMQNAGEARGLRSAAAAASMPREAKIFMKIVLRNLEHQQAESPEGMKVSYNRI
InterPro domains: - IPR016024: Armadillo-type fold (homologous_superfamily) [367-793]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [33-300]
- IPR001810: F-box domain (domain) [37-86]
- IPR011989: Armadillo-like helical (homologous_superfamily) [355-766]
- IPR006553: Leucine-rich repeat, cysteine-containing subtype (repeat) [178-229]
- IPR000225: Armadillo (repeat) [418-757]
Interaction partners: - U-box domain-containing protein 27
- Armadillo repeat only 1
- U-box domain-containing protein 5
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009791 (post-embryonic development), GO:0090696 (post-embryonic plant organ development), GO:0099402 (plant organ development), GO:0048731 (system development), GO:0048364 (root development), GO:0048528 (post-embryonic root development), GO:0022622 (root system development), GO:0048527 (lateral root development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Coiled-coil domain containing 106 (K7EMI9)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MNDRSSRRRTKPPEAASSALALMNSVKTQLHMALERNSWLQKRIEDLEEERDFLRCQLDKFISSARMEAEDHCRMKPGPRRMEGDSRGGAGGEASDPESAASSLSGASEEGSASERRRQKQKGGASRRRFGKPKARERQRVKDADGVLCRYKKILGTFQKLKSMSRAFEHHRVDRNTVALTTPIAELLIVAPEKLAEVGEFDPSKERLLEYSRRCFLALDDETLKKVQALKKSKLLLPITYRFKR
InterPro domains: - IPR031591: Coiled-coil domain-containing protein 106 (family) [10-244]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0090304 (nucleic acid metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0010467 (gene expression), GO:0018130 (heterocycle biosynthetic process), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0016070 (RNA metabolic process), GO:0032774 (RNA biosynthetic process), GO:0097659 (nucleic acid-templated transcription), GO:0006351 (DNA-templated transcription), GO:0006366 (transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Damage response protein 1 (Q12091)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Not known
Sequence: MSFIKNLLFGGVKTSEDPTGLTGNGASNTNDSNKGSEPVVAGNFFPRTLSKFNGHDDEKIFIAIRGKVYDCTRGRQFYGPSGPYTNFAGHDASRGLALNSFDLDVIKDWDQPIDPLDDLTKEQIDALDEWQEHFENKYPCIGTLIPEPGVNV
InterPro domains: - IPR050577: MAPR/Neuferricin/Neudesin-like (family) [33-145]
- IPR001199: Cytochrome b5-like heme/steroid binding domain (domain) [44-145]
- IPR036400: Cytochrome b5-like heme/steroid binding domain superfamily (homologous_superfamily) [39-147]
Interaction partners: - Lanosterol 14-alpha demethylase CYP51
- Cytochrome b5
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:0097159 (organic cyclic compound binding), GO:0008289 (lipid binding), GO:0005515 (protein binding), GO:0019842 (vitamin binding), GO:0005496 (steroid binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0062012 (regulation of small molecule metabolic process), GO:1902930 (regulation of alcohol biosynthetic process), GO:0019216 (regulation of lipid metabolic process), GO:0046890 (regulation of lipid biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019218 (regulation of steroid metabolic process), GO:0050810 (regulation of steroid biosynthetic process), GO:0106118 (regulation of sterol biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005739 (mitochondrion), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: U1 small nuclear ribonucleoprotein 70 kDa (A0A8I6G5W4)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKDERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDGAPDDGPPGELGPEGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDREHKRGERGSERGRDEARGGGGSGQDNGLEGLGSDGRDMYMEAEGGDGYMAPENGYLMEAAPE
InterPro domains: - IPR035979: RNA-binding domain superfamily (homologous_superfamily) [88-204]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [90-215]
- IPR051183: U1 snRNP 70 kDa and U11/U12 snRNP 35 kDa (family) [29-361]
- IPR022023: U1 small nuclear ribonucleoprotein of 70kDa N-terminal (domain) [3-94]
- IPR000504: RNA recognition motif domain (domain) [103-181]
- IPR034143: snRNP70, RNA recognition motif (domain) [102-187]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0043021 (ribonucleoprotein complex binding), GO:0070990 (snRNP binding), GO:1990446 (U1 snRNP binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0071495 (cellular response to endogenous stimulus), GO:1901700 (response to oxygen-containing compound), GO:0070848 (response to growth factor), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0071559 (response to transforming growth factor beta), GO:0034097 (response to cytokine), GO:1901701 (cellular response to oxygen-containing compound), GO:0071310 (cellular response to organic substance), GO:0033993 (response to lipid), GO:0071363 (cellular response to growth factor stimulus), GO:0032526 (response to retinoic acid), GO:0071560 (cellular response to transforming growth factor beta stimulus), GO:0071345 (cellular response to cytokine stimulus), GO:0034612 (response to tumor necrosis factor), GO:0071300 (cellular response to retinoic acid), GO:0071396 (cellular response to lipid), GO:0071356 (cellular response to tumor necrosis factor)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0140513 (nuclear protein-containing complex), GO:0005737 (cytoplasm), GO:0120114 (Sm-like protein family complex), GO:0030532 (small nuclear ribonucleoprotein complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0097525 (spliceosomal snRNP complex), GO:0043231 (intracellular membrane-bounded organelle), GO:0005685 (U1 snRNP), GO:0005634 (nucleus)