Protein: protein kinase C (A0A139WL43)
Organism: Tribolium castaneum (Red flour beetle)
Sequence: MFGKPDPQQQWSVHAEFTISHPRSDPDNLPQAHTEQADNGVRMTYTWTSSSQAASAWSAPPSTSSEGAPKYGFQKGNLLFTSTPPRRVHDSGYGSDLLSPNSYQRRPVQPYNRKCRSTCNIVLSTNIDENRTEETDSVHTQCGRTQSLRCQTPTLRCDRKDNFYGCGDPWCHHYEDFSGRFSPVMETCEDCPSGQASTKECDNRRDACVQTFEMIDKCTSPIVKMGRVKYAEYEDRKEKREKKKYGSGSRRRTEPIFQRSQSPSSITPDSLEGTKGQRRLVRKNATVGKDKDSSTDSKLSDSSKKPRTVHIDVYCTGTEMESDSSSESETASTPQTVFESEKVRITHKRADETEMPFSVRKSRSKSKEKEAKRIEESDDDGASTAYPSKLSSYSTIRDFESSISSVPQSWTPYSMSSCTVPDDYDSVANTSWKDTFSDIDSLIHSRSSIAQTESLDFVPRKLFEKNESIDETPEILETPSQESLQPSDSFEYANSEDRLRIKKMEEFWKNKTHSKHWKSPHVERRYLLQQKKIKEYLEKRLSDKNLPKGESKDSDSDASDGSEKGWTIVKEKNTELAPPKISDISCKSPSVLAIQQKLTMDPTLRAPFTIVPGIYTNQRAIAKKFGSIVPVVRKPGHHIGPVKNPDCLCEHCQRHFASVGHRGRTRSMGDPPSSFQNWKNIGYPQAESASNKRALKTWRISVEAQDSLRASSMKLDLLRKSLEMRRAELPADSPVAMQLKEELANAQTFSPLSVHYTSLQPFRERSNGNKMLTSSSTINRCAAVTGTLEVRLMGCQDLLEDVPGRPRKEADGSSSPMDLRFFKKGVTGRGSSKSYSIKDEVSDEIMAVLKLDNTTVAQTSWKPCSQQAWDQRFSIELDKHRELEIGVYWRDWRSLCAVKFLKLEEFIDDDRHGMALHLEPQGLLFAEIKFLNPMISKQPKLQRQKRIFKQVMPRAKQMNINIVTWGRWMKQSSRIPNRNNTIVQSTEMLPEEPEDKPETPGETPDPQAFGLGGQRPLGLGVAVLPETPPPVPTAPPPIAKKRMCVTPPPVPPRLDPESAAALKEFDFLEEQEMSRTGPLLIPSTPSPVVIPEQLVPPSPQPVIEFPDDEPPLEAVNVARRPVARELGYRDSAYESRRHSQYTGMSIDNFKLISVLGRGHFGKVILSQYRNTGEYFAIKALKKGDIIARDEVESLLSEKRIFEVANSIRHPFLVNLFACFQTEAHVCFVMEYAAGGDLMMHIHADVFSEPRAVFYAACVVLGLQYLHENKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGFGDRTGTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIFEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSLESIAIMRRLLRKIPDRRLGSSERDAEDVKKQAFFRHIQWDELLHRRVPPPFVPTVHSMEDVSNFDEEFTSEKPHLTPPKEPRPLTEQDQYLFRDFTYIADWC
InterPro domains: - IPR008271: Serine/threonine-protein kinase, active site (active_site) [1270-1282]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [1146-1463]
- IPR000719: Protein kinase domain (domain) [1149-1408]
- IPR017441: Protein kinase, ATP binding site (binding_site) [1155-1178]
- IPR000961: AGC-kinase, C-terminal (domain) [1409-1476]
- IPR000008: C2 domain (domain) [787-915]
- IPR035892: C2 domain superfamily (homologous_superfamily) [842-932]
- IPR017892: Protein kinase, C-terminal (domain) [1429-1471]
Interaction partners: - Serine/threonine-protein kinase N-like Protein
- 3-phosphoinositide-dependent protein kinase 1
- Ras-like GTP-binding protein Rho1
- Ras-like GTP-binding protein Rho1
- Rho1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023056 (positive regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010647 (positive regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0010646 (regulation of cell communication), GO:1902533 (positive regulation of intracellular signal transduction), GO:1902531 (regulation of intracellular signal transduction), GO:1901222 (regulation of NIK/NF-kappaB signaling), GO:1901224 (positive regulation of NIK/NF-kappaB signaling)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)