Protein: Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2) (Q5U1Y2)
Organism: Rattus norvegicus (Rat)
Function: Not known
Sequence: MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKDTIEKLKEKKLAPITYPQGLALAKDIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQQKRPCSLL
InterPro domains: - IPR001806: Small GTPase (family) [1-192]
- IPR003578: Small GTPase Rho (family) [3-186]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [1-182]
- IPR005225: Small GTP-binding domain (domain) [1-156]
Interaction partners: - Neutrophil cytosolic factor 1
- NADPH oxidase 2
- Cytochrome b-245 light chain
- Neutrophil cytosol factor 4
- Proto-oncogene vav
- Dedicator of cytokinesis 2
- Serine/threonine-protein kinase PAK 1
- Plexin-B1
- TIAM Rac1 associated GEF 1
- Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0097367 (carbohydrate derivative binding), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0016787 (hydrolase activity), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0005515 (protein binding), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:1901265 (nucleoside phosphate binding), GO:0043168 (anion binding), GO:0000166 (nucleotide binding), GO:0019899 (enzyme binding), GO:0032553 (ribonucleotide binding), GO:0035639 (purine ribonucleoside triphosphate binding), GO:0051117 (ATPase binding), GO:0019900 (kinase binding), GO:0051020 (GTPase binding), GO:0032555 (purine ribonucleotide binding), GO:0042826 (histone deacetylase binding), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0017076 (purine nucleotide binding), GO:0016462 (pyrophosphatase activity), GO:0005525 (GTP binding), GO:0019001 (guanyl nucleotide binding), GO:0031267 (small GTPase binding), GO:0032561 (guanyl ribonucleotide binding), GO:0019901 (protein kinase binding), GO:0017111 (ribonucleoside triphosphate phosphatase activity), GO:0003924 (GTPase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0042592 (homeostatic process), GO:0048871 (multicellular organismal-level homeostasis), GO:0071840 (cellular component organization or biogenesis), GO:0030029 (actin filament-based process), GO:0048771 (tissue remodeling), GO:0046849 (bone remodeling), GO:0030036 (actin cytoskeleton organization), GO:0016043 (cellular component organization), GO:0060249 (anatomical structure homeostasis), GO:0001894 (tissue homeostasis), GO:0006996 (organelle organization), GO:0045453 (bone resorption), GO:0007010 (cytoskeleton organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0005829 (cytosol), GO:0071944 (cell periphery), GO:0030054 (cell junction), GO:0098794 (postsynapse), GO:0036477 (somatodendritic compartment), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0120025 (plasma membrane bounded cell projection), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0005794 (Golgi apparatus), GO:0043197 (dendritic spine), GO:0097447 (dendritic tree), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0098982 (GABA-ergic synapse), GO:0098588 (bounding membrane of organelle), GO:0030425 (dendrite), GO:0043005 (neuron projection), GO:0031982 (vesicle), GO:0000139 (Golgi membrane), GO:0097708 (intracellular vesicle), GO:0044309 (neuron spine)