Protein: Peroxidase mlt-7 (EC 1.11.1.7) (Molting defective protein 7) (MoLT-7) [Cleaved into: Peroxidase mlt-7 light chain; Peroxidase mlt-7 heavy chain] (Q23490)
Organism: Caenorhabditis elegans
Function: Plays an essential role in cuticle biogenesis. Required in combination with bli-3 for correct formation of cross-links in cuticle collagens.
Sequence: MRRLHRNLSLLFLICILNEYRIESQTLSPPITDRFKCLTNGCCDHHEWCRFWASIGECNANKDWMTENCQLACGTCTAPAAPLLPVTTTASSFNGGGFVQTTTQSSGPTTTITIPPSSLTSVTSCERVKDSIAQASELMSISRLINPVEDNFGRNMLSIDDITRSVPTGCVPQLSDVGVDCRKSLCYHLMYRTLDGTCNNLEKPMQGAAFRRFNRHFPAQYDDGKGEPISSLNQSRPSAREANRVMLSSAQSVVHDKFNNMMMQWGQFMSHDMSKTTLQPSANCKTCDPVPSKCMPIPIGEKDPNLGFKSKQCLKVSRSAPICRVEPREQLNENTAYIDGSMIYGSSLKDLHKFRDGRTGFLRVTRFNNQNVLPFDQSKCANKDKCTASFTAGDIRANLFIGLSSLHIMFAREHNRIAQKLTELNPTWSGDRVFQEARKIVGAQIQNVLYKEYLPKLLGVSFDKVIGPYKGYDTNVDATIANEFTTSAFRFGHGMIEEFYKRVDLSGNNITHGGFFFGDGVFKSGKILFEGGVDPIIRGFMTTAVKRPHRMTPAITEKMFGSTDLGSLNIQRGRDHGIPSYNKMRQFCGLKSANTFDDFADMILDRNLRAGLARNYNTTNDVDFYVGSMLEDPVIGGLVGTTLSCAIGEQFKRARDGDRFYFENPGIFTRSQMEEIKKSSLSRIICDNADNFELVSQDAFLLPGSNLTPCSKIPKMDLSKWRAL
InterPro domains: - IPR019791: Haem peroxidase, animal-type (family) [178-724]
- IPR010255: Haem peroxidase superfamily (homologous_superfamily) [185-722]
- IPR037120: Haem peroxidase domain superfamily, animal type (homologous_superfamily) [175-723]
- IPR003582: ShKT domain (domain) [41-77]
Interaction partners: - Dual oxidase maturation factor 1
- Tetraspanin-15
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0016209 (antioxidant activity), GO:0003824 (catalytic activity), GO:0004601 (peroxidase activity), GO:0016491 (oxidoreductase activity), GO:0016684 (oxidoreductase activity, acting on peroxide as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0009653 (anatomical structure morphogenesis), GO:0044237 (cellular metabolic process), GO:0042303 (molting cycle), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0032989 (cellular component morphogenesis), GO:0000902 (cell morphogenesis), GO:0010171 (body morphogenesis), GO:0048598 (embryonic morphogenesis), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0016043 (cellular component organization), GO:0009790 (embryo development), GO:0042335 (cuticle development), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0000904 (cell morphogenesis involved in differentiation), GO:0030154 (cell differentiation), GO:0045229 (external encapsulating structure organization), GO:0043062 (extracellular structure organization), GO:0010172 (embryonic body morphogenesis), GO:0009792 (embryo development ending in birth or egg hatching), GO:0030198 (extracellular matrix organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062023 (collagen-containing extracellular matrix), GO:0005604 (basement membrane)