Protein: ATP-dependent RNA helicase DHX30 (A0A8N7TE51)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm. Mitochondrion matrix, mitochondrion nucleoid
Sequence: MAMSSALTPLRALLSLRSKTLEINKDIRSRWAFIRQYRSKPDVVHTRRHSPPETINKAHPDYLHAKNLLYNTLSRSVGLSNVSQYLKFSCTDGEVKRATVTLLWPVRIETEGFGSRKQEAERNAAAAALQKLCELGVYAPGKRRQEAGMLRMKDRQTSLCDNEEENHLQSLPIQKKTQKDRAHGLVEEDSRLSEALAIFPRPRTLLGSVIQVATSSCRVRDLLQYKTSGGKVKVCELNVLWPTPMTFTASGRRRLEAEANAAALACLKLKELNLLDEQNKPLTHARYHQDQVREAGERHRQPCRMQIPEQLELRIQQYLSQYPVEAEVQKLWDEEEHQSSSISTAADDYDEDEFITDAITSKPYRALEPKEAEHLSQRLLSMWKRVGPARGAELPVDAHKESILEAVRSSQVVVISGETGCGKTTRIPRFLLEDGVLRGEGAECNVLVTQPRRISAVSVAQRVAHEIGPALQHCVGYQVRLESRPPERSGGALLFLTLGVLLKKLQSNPRLEGISHVIVDEVHERDVQTDLLLHLLRCVLSLRPELKVLLMSASGDSQRLAQYFGGCPVLRVPGFMHPVRARFLEDMQLDSRRPLLDMGSTQWSAEVRGRMGKEENNVTPDLDLVADVIDHIHRTGEPGAVLCFLPGWQEIKAVQQQLEEKQAYRSGSQIILPLHSSMAVSEQQVVFQRPPAGQRKIVLATNIAETSITIDDIVHVVDAGVQKEQNYDPRTKVSALNTVWISQANVTQRRGRAGRCQPGHSYHLFPRKQLERMEPFPVPEILRTPLESVVMQAKIHCPESKAEDFLSQVLDSPDTQAVRTAVKNLMDIGVLDASEDLTPLGHHVSCMSCDPRLGKVLVFSALFSCVQPVLSVVACLTRDPFYNSLQNRTLVSKAKAELSGSSGSDYLVFSRVVQSWREQHSRDSRQDYLDKHTLSGASLRFIHGLMQQFSDNLCEAGLVDHSAECLRLSSPVNQQSKEEQLITAVLLAGLYPNLIQVKKGVVTKSGRFRAENVSFRTESGPVLLHRSSVNRDKQHLWSRWLTFFSAVKSSGQVFIRDSTVVHPLALLLLTDCDLSERVVGDRVEVALPGPALIRWEFSPAVWELLWDLRASIQAMIYRKLRQSECKSSSEQRKDSELIDLLVDLLNNTDPDVSRDQEDALNSSNTENAEADSC
InterPro domains: - IPR056755: dsRNA binding domain (domain) [64-132]
- IPR011545: DEAD/DEAH-box helicase domain (domain) [401-554]
- IPR001650: Helicase, C-terminal domain-like (domain) [627-797]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [392-582]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [345-918]
- IPR014720: Double-stranded RNA-binding domain (domain) [111-134]
- IPR002464: DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site (conserved_site) [515-524]
- IPR007502: Helicase-associated domain (domain) [820-910]
- IPR011709: DEAD-box helicase, OB fold (domain) [982-1070]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0016887 (ATP hydrolysis activity), GO:0004386 (helicase activity), GO:1901363 (heterocyclic compound binding), GO:0016787 (hydrolase activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0097159 (organic cyclic compound binding), GO:0008186 (ATP-dependent activity, acting on RNA), GO:0003676 (nucleic acid binding), GO:0140098 (catalytic activity, acting on RNA), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0003724 (RNA helicase activity), GO:0003723 (RNA binding), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity), GO:0017111 (ribonucleoside triphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0009653 (anatomical structure morphogenesis), GO:0032989 (cellular component morphogenesis), GO:0000902 (cell morphogenesis), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0032990 (cell part morphogenesis), GO:0070584 (mitochondrion morphogenesis), GO:0007005 (mitochondrion organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)