Protein: Rac GTPase-activating protein 1 (Q6P3H8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Sequence: METAVMNLHSIFESLRAQADVLNESIEPQFIQLAINFEDNRRRWLRLEQELNACKEVLTKAETERGALEVKLKHARNQVDVEIRRRQKAESDCAKLDRQIQLIRELLVSEGSSSSIQLNEEQRSALAFLNARSQNPANLNTSRRLATIDESASILSDISYDKTDDSLDWDSSAIRTVRLKKRQKRRSSRNHTEGPPAAAKRSRSTGRTSEKGNESLVAKTTVTVPADGGPIEAVTTVEAVPYWTRSRRKTVFCSSEQCISLNYSSAAVEWDTVDTDSVQSMDVFKQPSLPNAENRAEPSTPQGNGGVRLHEFISKTVIKPESCVPCGKRIKFGKISLKCRDCRVVAHPECRERCPLPCIPSMTGTPVKIGEGTLANYVSNTSPMIPSLVVHCINEIEQRGLHETGLYRVSGSDRVVKDLKEKFLRGKTVPLLSKVEDIHAITGLLKDFLRNLKEPLLTFRLNRAFMDAAELSDDDNSIALMYQNISDLPQPHRDTLAFLIIHLQRVAQSPATKMDITNLARVFGPTIVGHAVSNPEPMTILQDTKRQPRVVERLLSLPVEYWSQFMISDHDHARNDHMIIENANVHTTPDQKMSMFGPITTPDQQMSKTPSSSSLSQRMKNATLNAITPKFSSRSRATAAVPRQGNFFASPLLK
InterPro domains: - IPR046349: C1-like domain superfamily (homologous_superfamily) [302-361]
- IPR008936: Rho GTPase activation protein (homologous_superfamily) [364-569]
- IPR000198: Rho GTPase-activating protein domain (domain) [372-562]
- IPR002219: Protein kinase C-like, phorbol ester/diacylglycerol-binding domain (domain) [309-359]
Interaction partners: - Kinesin-like protein
- Epithelial cell-transforming 2
- Kinesin-like protein
- Kinesin family member 11
- Kinesin family member 20Ba
- Protein regulator of cytokinesis 1b.
- Anillin
- SHC SH2-domain-binding protein 1.
- Nucleolar and spindle-associated protein 1
- Uncharacterized protein.
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0008047 (enzyme activator activity), GO:0060589 (nucleoside-triphosphatase regulator activity), GO:0030695 (GTPase regulator activity), GO:0005096 (GTPase activator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007017 (microtubule-based process), GO:0071840 (cellular component organization or biogenesis), GO:0051301 (cell division), GO:0022402 (cell cycle process), GO:0007049 (cell cycle), GO:0016043 (cellular component organization), GO:0000278 (mitotic cell cycle), GO:0000910 (cytokinesis), GO:0000226 (microtubule cytoskeleton organization), GO:1903047 (mitotic cell cycle process), GO:0061640 (cytoskeleton-dependent cytokinesis), GO:0006996 (organelle organization), GO:0000281 (mitotic cytokinesis), GO:0007010 (cytoskeleton organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0048471 (perinuclear region of cytoplasm), GO:0071944 (cell periphery), GO:0140535 (intracellular protein-containing complex), GO:0030496 (midbody), GO:0099080 (supramolecular complex), GO:0032153 (cell division site), GO:0005737 (cytoplasm), GO:0005881 (cytoplasmic microtubule), GO:0043229 (intracellular organelle), GO:0032154 (cleavage furrow), GO:0005938 (cell cortex), GO:0043228 (non-membrane-bounded organelle), GO:0098590 (plasma membrane region), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0099081 (supramolecular polymer), GO:0055028 (cortical microtubule), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0030863 (cortical cytoskeleton), GO:0099512 (supramolecular fiber), GO:0099513 (polymeric cytoskeletal fiber), GO:0030981 (cortical microtubule cytoskeleton), GO:0005634 (nucleus), GO:0005856 (cytoskeleton), GO:0005819 (spindle), GO:0005874 (microtubule), GO:0072686 (mitotic spindle), GO:0015630 (microtubule cytoskeleton)