Protein: Pumilio/PUF RNA binding protein 8, putative (Q582W0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MGKTNTKKQEARVARLRSLPKSERLVKIARIKKREGRILDSAEKHALKMSSEYGEIIRLWEVLRTSEGQSKEEEEKEKQKKKGKNKKGEDSTDDVKQQKLSRYKHKYPTVDKLLKKIEPKFDTYVRTPRTSRVIQSMIKYGSTEQLGKIVGLISSGYANYATDAYGHFVVVALLRHAPHDLFDKILSLTIPAVPTLISHRFGIEVIHSAYSSNLCTATNRNLLILAVFKDNIALMKRWKGYPILEDVLAQEVEQRKRLLPKLFELCEKLVSQKSAVDFPFVQRLAAAFIRNGTKHEVSELCDTLRPHLAVLCTIREGAPLASLAFSLTEPKKRKVILRAFSENLGVLVVSKYSAPVIARLFDIVYDVQLLCKYVVNDVVSHITQLINSPFGHQILLHLLTPHDERKTKFLLPNWFQHNLYSVENTRWNCHTWLTHEYKEEEVELCSKDAEQTHLAVLPTLIKKFLEVLSNSEVASKLNKHYVGLIAREVLHVHEKEPAYRKALKLSANDVQVLERLSLSRGKKEPRHEEGGNSVGKITSEVQNKTKGRRLERPQMQKPAETPRVVKKMMKSSGVERSRKEGTKVETVSHAVSTLKKKKKVLPKK
InterPro domains: - IPR016024: Armadillo-type fold (homologous_superfamily) [108-416]
- IPR033133: Pumilio homology domain (domain) [91-439]
- IPR011989: Armadillo-like helical (homologous_superfamily) [89-517]
- IPR040059: Pumilio homologue 3 (family) [3-585]
- IPR001313: Pumilio RNA-binding repeat (repeat) [116-412]
Interaction partners: - Nucleolar protein, putative
- rRNA processing protein, putative
- Ribosome production factor 2 homolog
- Ribosome biogenesis protein, putative
- Nucleolar GTP-binding protein 1
- RNA-binding protein, putative
- RNA-binding protein, putative
- Ribosomal protein L1p/L10e family
- ATP-dependent RNA helicase
- Peter pan protein, putative
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0065008 (regulation of biological quality), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0048522 (positive regulation of cellular process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0031647 (regulation of protein stability), GO:0009891 (positive regulation of biosynthetic process), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0034248 (regulation of amide metabolic process), GO:0034250 (positive regulation of amide metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0051246 (regulation of protein metabolic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0051247 (positive regulation of protein metabolic process), GO:0010628 (positive regulation of gene expression), GO:0050821 (protein stabilization), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0010468 (regulation of gene expression), GO:2000112 (regulation of cellular macromolecule biosynthetic process), GO:0006417 (regulation of translation), GO:0045727 (positive regulation of translation), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)