wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Rhombotin-2 (LIM domain only protein 2) (LMO-2) (zlmo2) (Q9PTJ3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Transcription factor that acts synergistically with tal1/scl in primitive and definitive hematopoiesis, and in endothelial development. Specifies mesodermal precursors to a hemangioblast cell fate. Hemangioblasts are bipotential precursors of blood and endothelium, and in the absence of hematopoietic induction cues such as gata1, tal1/scl-lmo2-induced haemangioblasts differentiate into endothelial cells.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P25801}.
Sequence: MASTIERKTLEANEEPVDEVLQMPPSLLTCGGCQQSIGDRFFLKAIEQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCEKRIRAFEMTMRVRDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQDIFEWTKLNGSIV
InterPro domains: - IPR050945: LMO/RBTN Transcription Factors (family) [2-157]
- IPR001781: Zinc finger, LIM-type (domain) [28-154]
Interaction partners: - T-cell acute lymphocytic leukemia protein 1 homolog
- GATA-binding protein 1a.
- LIM domain-binding protein 1-A.
- Endothelial transcription factor GATA-2a
- BHLH domain-containing protein.
- Transcription factor 3a.
- Runt-related transcription factor
- LIM domain-binding protein 1-A
- Fli-1 protein
- Growth factor-independent 1A transcription repressor b.
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0042592 (homeostatic process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0048871 (multicellular organismal-level homeostasis), GO:0002262 (myeloid cell homeostasis), GO:0034101 (erythrocyte homeostasis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048872 (homeostasis of number of cells), GO:0030097 (hemopoiesis), GO:0030218 (erythrocyte differentiation), GO:0030099 (myeloid cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Vesicle transport v-SNARE N-terminal domain-containing protein (Q57YW6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00046280}; Single-pass type IV membrane protein {ECO:0000256|ARBA:ARBA00046280}.
Sequence: MSSDLLREYENDFNETLKEANDVASRLQESLQRSGVSYQAPPAAGPQSRSQQCHSLQQSLTRLRELITNMSYESNEVEPASAKEEVKRRLEDYRGKLVALEKQLSRLRQESREADRTDLLGNGREMGDDGGSMEEHARMLGTTTKLKEGTGALQKAEALLHGTNELGLETLSVVRGQTETMKHIHGVVIDVDDDVTESRRIVHRMQQVARKQKLIMAGVIGMLVFTFLIIVFWK
InterPro domains: - IPR027027: GOSR2/Membrin/Bos1 (family) [9-234]
- IPR007705: Vesicle transport v-SNARE, N-terminal (domain) [1-107]
- IPR010989: SNARE (homologous_superfamily) [43-108]
- IPR038407: Vesicle transport v-SNARE, N-terminal domain superfamily (homologous_superfamily) [1-115]
Interaction partners: - Vesicle-associated membrane protein, putative
- Syntaxin 5
- Vacuolar protein sorting 33, putative
- Pep3/Vps18/deep orange beta-propeller domain-containing protein
- Vacuolar assembly protein vps41, putative
- RING-type domain-containing protein
- Vacuolar protein sorting complex subunit, putative
- Syntaxin, putative
- Vacuolar protein sorting-associated protein 45, putative
- Syntaxin, putative
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060090 (molecular adaptor activity), GO:0030674 (protein-macromolecule adaptor activity), GO:0005484 (SNAP receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0043233 (organelle lumen), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0099568 (cytoplasmic region), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005929 (cilium), GO:0032838 (plasma membrane bounded cell projection cytoplasm), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0097014 (ciliary plasm), GO:0005634 (nucleus)
Protein: Fructose-1,6-bisphosphatase class 2 (FBPase class 2) (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2) (Q6M6E7)
Organism: Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)
Function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Is essential for growth on gluconeogenic carbon sources. Also displays a low activity toward glucose 6-phosphate, and fructose 6-phosphate, glycerol 3-phosphate, ribulose 1,5-bisphosphate and myo-inositol-monophosphate are not significant substrates.
Subcellular location: Cytoplasm {ECO:0000250}.
Sequence: MNLKNPETPDRNLAMELVRVTEAAALASGRWVGRGMKNEGDGAAVDAMRQLINSVTMKGVVVIGEGEKDEAPMLYNGEEVGTGFGPEVDIAVDPVDGTTLMAEGRPNAISILAAAERGTMYDPSSVFYMKKIAVGPEAAGKIDIEAPVAHNINAVAKSKGINPSDVTVVVLDRPRHIELIADIRRAGAKVRLISDGDVAGAVAAAQDSNSVDIMMGTGGTPEGIITACAMKCMGGEIQGILAPMNDFERQKAHDAGLVLDQVLHTNDLVSSDNCYFVATGVTNGDMLRGVSYRANGATTRSLVMRAKSGTIRHIESVHQLSKLQEYSVVDYTTAT
InterPro domains: - IPR004464: Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase (family) [9-329]
Interaction partners: - Transketolase
- Fructose-bisphosphate aldolase
- Transaldolase
- Glucose-6-phosphate isomerase
- ATP-dependent 6-phosphofructokinase
- Fructose-1-phosphate kinase and related fructose-6-phosphate kinase
- Fructose-1-phosphate kinase and related fructose-6-phosphate kinase
- mannose-6-phosphate isomerase
- Glyceraldehyde-3-phosphate dehydrogenase
- Glucose-6-phosphate 1-dehydrogenase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0016791 (phosphatase activity), GO:0019203 (carbohydrate phosphatase activity), GO:0050308 (sugar-phosphatase activity), GO:0042132 (fructose 1,6-bisphosphate 1-phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006066 (alcohol metabolic process), GO:0005975 (carbohydrate metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044283 (small molecule biosynthetic process), GO:0044262 (cellular carbohydrate metabolic process), GO:1901617 (organic hydroxy compound biosynthetic process), GO:0019400 (alditol metabolic process), GO:0046165 (alcohol biosynthetic process), GO:0019751 (polyol metabolic process), GO:0016051 (carbohydrate biosynthetic process), GO:0034637 (cellular carbohydrate biosynthetic process), GO:0046173 (polyol biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Mitochondrial dicarboxylate carrier (DIC) (Solute carrier family 25 member 10) (O89035)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the electroneutral exchange or flux of physiologically important metabolites such as dicarboxylates (malonate, malate, succinate), inorganic sulfur-containing anions, and phosphate, across mitochondrial inner membrane. Plays an important role in gluconeogenesis, fatty acid metabolism, urea synthesis, and sulfur metabolism, particularly in liver, by supplying the substrates for the different metabolic processes. Regulates fatty acid release from adipocytes, and contributes to systemic insulin sensitivity (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000305|PubMed:3355813}; Multi-pass membrane protein.
Sequence: MAEARTSRWYFGGLASCGAACCTHPLDLLKVHLQTQQEVKLRMTGMALQVVRTDGFLALYNGLSASLCRQMTYSLTRFAIYETMRDYMTKDSQGPLPFYSKVLLGGISGLTGGFVGTPADLVNVRMQNDMKLPLSQRRNYSHALDGLYRVAREEGLKKLFSGATMASSRGALVTVGQLSCYDQAKQLVLSTGYLSDNIFTHFLSSFIAGGCATFLCQPLDVLKTRLMNSKGEYQGVFHCAVETAKLGPQAFFKGLVPAGVRLVPHTVLTFMFLEQLRKHFGIKVAT
InterPro domains: - IPR018108: Mitochondrial carrier protein, transmembrane region (repeat) [7-281]
- IPR023395: Mitochondrial carrier protein domain superfamily (homologous_superfamily) [7-283]
- IPR002067: Mitochondrial carrier protein (family) [81-286]
- IPR050391: Mitochondrial Metabolite Transporter (family) [6-277]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity), GO:0005342 (organic acid transmembrane transporter activity), GO:0046943 (carboxylic acid transmembrane transporter activity), GO:0005310 (dicarboxylic acid transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0015849 (organic acid transport), GO:0015711 (organic anion transport), GO:0046942 (carboxylic acid transport), GO:0006835 (dicarboxylic acid transport), GO:0015740 (C4-dicarboxylate transport), GO:0015744 (succinate transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Growth hormone secretagogue receptor type 1 (GH-releasing peptide receptor) (Ghrelin receptor) (C7G181)
Organism: Coturnix japonica (Japanese quail) (Coturnix coturnix japonica)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Sequence: MRSRSGTMREGSAENRTGGESPLRLFPAPVLTGITVACVLLFVVGVLGNMMTMLVVSRFRDMRTTTNFYLSSMAFSDLLIFLCMPLDLFRLWQYRPWNFGDLLCKLFQFISESCTYSTILNITALSVERYVAICFPLRAKVIITKRKVKLVILILWAISFISAGPIFVLVGVEHENGTNPLSTNECRATEYAIRSGLLTIMVWISSIFFFLPVFCLTVLYSLIGRKLWRRKRKNIGPSTVIRDKNNKQTVKMLVVVVFAFILCWLPFHVGRYLFSKSFEAGSLEIAVISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAACRLFGLKTLPKKRLSSTKQDSSRVWTEPTVAT
InterPro domains: - IPR017452: GPCR, rhodopsin-like, 7TM (domain) [48-311]
- IPR000276: G protein-coupled receptor, rhodopsin-like (family) [33-319]
- IPR003905: Growth hormone secretagogue receptor/motilin receptor (family) [25-353]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0033218 (amide binding), GO:0042562 (hormone binding), GO:0017046 (peptide hormone binding), GO:0042277 (peptide binding), GO:0004888 (transmembrane signaling receptor activity), GO:0004930 (G protein-coupled receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007186 (G protein-coupled receptor signaling pathway), GO:0007218 (neuropeptide signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)
Protein: Cell division protein ZipA (FtsZ interacting protein A) (P77173)
Organism: Escherichia coli (strain K12)
Function: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of the downstream cell division proteins FtsK, FtsQ, FtsL and FtsN. ZipA overproduction protects FtsZ from degradation by ClpP by preventing recognition by ClpX. Does not affect the GTPase activity of FtsZ.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:16079137, ECO:0000269|PubMed:9008158}; Single-pass type I membrane protein {ECO:0000269|PubMed:9008158}. Note=Localizes to the Z ring in an FtsZ-dependent manner (PubMed:10209756, PubMed:9008158, PubMed:9864327). Localization does not depend upon FtsA or FtsI (PubMed:10209756, PubMed:9864327). {ECO:0000269|PubMed:10209756, ECO:0000269|PubMed:9008158, ECO:0000269|PubMed:9864327}.
Sequence: MMQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRMKSKRDDDSYDEDVEDDEGVGEVRVHRVNHAPANAQEHEAARPSPQHQYQPPYASAQPRQPVQQPPEAQVPPQHAPHPAQPVQQPAYQPQPEQPLQQPVSPQVAPAPQPVHSAPQPAQQAFQPAEPVAAPQPEPVAEPAPVMDKPKRKEAVIIMNVAAHHGSELNGELLLNSIQQAGFIFGDMNIYHRHLSPDGSGPALFSLANMVKPGTFDPEMKDFTTPGVTIFMQVPSYGDELQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDIIREVKDANA
InterPro domains: - IPR036765: ZipA, C-terminal FtsZ-binding domain superfamily (homologous_superfamily) [189-328]
- IPR011919: Cell division protein ZipA (family) [2-328]
- IPR007449: ZipA, C-terminal FtsZ-binding domain (domain) [191-320]
Interaction partners: - Cell division protein FtsA
- Cell division protein FtsZ
- Cell division protein FtsQ
- Cell division protein FtsN
- Cell division protein FtsL
- Cell division ATP-binding protein FtsE
- Probable peptidoglycan glycosyltransferase FtsW
- DNA translocase FtsK
- Peptidoglycan D,D-transpeptidase FtsI
- Cell division protein ZapA
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050794 (regulation of cellular process), GO:1900190 (regulation of single-species biofilm formation), GO:1900231 (regulation of single-species biofilm formation on inanimate substrate)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: FKBP-type peptidyl-prolyl cis-trans isomerase FkpA (PPIase) (EC 5.2.1.8) (Rotamase) (P45523)
Organism: Escherichia coli (strain K12)
Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Subcellular location: Periplasm.
Sequence: MKSLFKVTLLATTMAVALHAPITFAAEAAKPATAADSKAAFKNDDQKSAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAFADKSKLSDQEIEQTLQAFEARVKSSAQAKMEKDAADNEAKGKEYREKFAKEKGVKTSSTGLVYQVVEAGKGEAPKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGLKNIKKGGKIKLVIPPELAYGKAGVPGIPPNSTLVFDVELLDVKPAPKADAKPEADAKAADSAKK
InterPro domains: - IPR036944: Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily (homologous_superfamily) [26-142]
- IPR000774: Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal (domain) [46-152]
- IPR046357: Peptidyl-prolyl cis-trans isomerase domain superfamily (homologous_superfamily) [143-257]
- IPR001179: FKBP-type peptidyl-prolyl cis-trans isomerase domain (domain) [159-249]
Interaction partners: - Periplasmic serine endoprotease DegP
- Chaperone SurA
- Thiol:disulfide interchange protein DsbC
- Chaperone protein Skp
- Thiol:disulfide interchange protein DsbA
- Periplasmic chaperone PpiD
- Chaperone protein HtpG
- Trigger factor
- FKBP-type peptidyl-prolyl cis-trans isomerase SlyD
- Peptidyl-prolyl cis-trans isomerase B
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016853 (isomerase activity), GO:0097159 (organic cyclic compound binding), GO:0033218 (amide binding), GO:1901363 (heterocyclic compound binding), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0016859 (cis-trans isomerase activity), GO:0003755 (peptidyl-prolyl cis-trans isomerase activity), GO:0005527 (macrolide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0006457 (protein folding), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0061077 (chaperone-mediated protein folding), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0018193 (peptidyl-amino acid modification), GO:0018208 (peptidyl-proline modification), GO:0000413 (protein peptidyl-prolyl isomerization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0031975 (envelope), GO:0042597 (periplasmic space), GO:0030313 (cell envelope), GO:0030288 (outer membrane-bounded periplasmic space)
Protein: Odorant receptor 85a (Q9VHS4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates. The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration. May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability.
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Sequence: MIFKYIQEPVLGSLFRSRDSLIYLNRSIDQMGWRLPPRTKPYWWLYYIWTLVVIVLVFIFIPYGLIMTGIKEFKNFTTTDLFTYVQVPVNTNASIMKGIIVLFMRRRFSRAQKMMDAMDIRCTKMEEKVQVHRAAALCNRVVVIYHCIYFGYLSMALTGALVIGKTPFCLYNPLVNPDDHFYLATAIESVTMAGIILANLILDVYPIIYVVVLRIHMELLSERIKTLRTDVEKGDDQHYAELVECVKDHKLIVEYGNTLRPMISATMFIQLLSVGLLLGLAAVSMQFYNTVMERVVSGVYTIAILSQTFPFCYVCEQLSSDCESLTNTLFHSKWIGAERRYRTTMLYFIHNVQQSILFTAGGIFPICLNTNIKMAKFAFSVVTIVNEMDLAEKLRRE
InterPro domains: - IPR004117: Olfactory receptor, insect (family) [37-388]
Interaction partners: - Odorant receptor 85b
- Odorant receptor 47a
- Odorant receptor 56a
- Putative odorant receptor 92a
- Odorant receptor 67d
- Odorant receptor 67a
- Odorant receptor 10a
- Odorant receptor 43a
- Odorant receptor 88a
- Odorant receptor 65a
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004984 (olfactory receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0003008 (system process), GO:0051606 (detection of stimulus), GO:0042221 (response to chemical), GO:0050906 (detection of stimulus involved in sensory perception), GO:0050877 (nervous system process), GO:0009593 (detection of chemical stimulus), GO:0007600 (sensory perception), GO:0050907 (detection of chemical stimulus involved in sensory perception), GO:0007606 (sensory perception of chemical stimulus), GO:0050911 (detection of chemical stimulus involved in sensory perception of smell), GO:0007608 (sensory perception of smell)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)
Protein: Protein NRT1/ PTR FAMILY 2.3 (AtNPF2.3) (Probable nitrate excretion transporter 3) (Protein NAXT1-like 2) (Q9M175)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transporter involved in a passive nitrate efflux.
Subcellular location: Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Sequence: MASLVSGDKEAQISGDPGSKRGGWITFPFMLATLLGLSVTSFGWVMNLIVFLIEEFNIKSIAAAQISNVANGCLSMLPVVAAILADSFFGNIPVIAASSFISLLGIVLLTLIASLDYLRPRPCEAGSVLCTPPSKLHLGILYTALALVTTGAGGTRFTMASAGANQYEKPKEQGSFFNWYFLTLYAGAITGATAIVYIQDNASWKLGFGLCAAANLISFIVFVSGKRYYKHDKPMGSPFTSLIRVVVSATVKRKAVISCNEEDYHHYGLEKEVKTSAAMPSKSFRFLNRAALMTKDDLNQKEGSVNNIWRLCSVQEVEDFKAILRVFPLWLSIIFVSTPMVMQTSLIVLQALVTDRGLGPNFKVPAGSLQVIIIITACIVIIMNNWLVFPMYKKLTHKLLTPLQKVGIGQVLTILSMALSAVVEAKRLKTVENGHPMSVLWLFPPLVIVGIGEAFQFPANIELFYGEFPESLRNTATSLTSVVIGISFYLSTALIDLIQRTTAWLPNDINHGRVDNVYWLLVIGGILNFGYFLVCSWVYKYRNLKDNDQEQDPKDGTM
InterPro domains: - IPR036259: MFS transporter superfamily (homologous_superfamily) [4-549]
- IPR018456: PTR2 family proton/oligopeptide symporter, conserved site (conserved_site) [81-105]
- IPR000109: Proton-dependent oligopeptide transporter family (family) [94-503]
Interaction partners: - High affinity nitrate transporter 2.5
- Peptide transporter family protein
- Uncharacterized protein At5g19190
- High affinity nitrate transporter 2.4
- At5g43870)
- Tagatose-6-phosphate ketose/aldose isomerase, putative
- High affinity nitrate transporter 2.7
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0008509 (monoatomic anion transmembrane transporter activity), GO:0015108 (chloride transmembrane transporter activity), GO:0015103 (inorganic anion transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:0070887 (cellular response to chemical stimulus), GO:1902074 (response to salt), GO:0006810 (transport), GO:0006811 (monoatomic ion transport), GO:0015698 (inorganic anion transport), GO:1902075 (cellular response to salt), GO:0006821 (chloride transport), GO:0006820 (monoatomic anion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)