Protein: Protein farnesyltransferase subunit beta (FTase-beta) (EC 2.5.1.58) (Q6IQG3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Sequence: MEEAPPSLRCFQESHSSELFNDDGLQTVTSREQRKVERSIQEVYSVYQQIHTSPQPALLREQHYHYLKKGLRHLSDAYECLDASRPWLCYWILHSLELLEEPVPAAVASDVCQFLARCQAPTGGFGGGPGQQAHLAPTYAAVNALCILGTEEAYNVINRETLLDFLYSVKQPDGSFVMHIGGEVDVRSAYCAASVASLTNIIAPTLFDGTHNWIISCQNWEGGLGGVPGLEAHGGYTFCGTAALVILGKEHMLDLKALLRWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALFKEGDSTLSVSSWMFERKALQEYILLCCQNPGGGLLDKPGKSRDFYHTSYCLSGLSVAQHFGNKDLHNELILGRDENKLAPTHPVYNICPEKVARAVEYFHRLPVPIPTGATASAMDQS
InterPro domains: - IPR008930: Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid (homologous_superfamily) [19-404]
- IPR026872: Protein farnesyltransferase subunit beta (family) [60-358]
- IPR045089: Prenyltransferase subunit beta (family) [58-401]
- IPR001330: Prenyltransferase alpha-alpha toroid domain (domain) [58-388]
Interaction partners: - Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
- Alkyl transferase
- Geranylgeranyl diphosphate synthase 1
- CAAX prenyl protease 2
- CAAX prenyl protease 2
- All trans-polyprenyl-diphosphate synthase PDSS1
- CAAX prenyl protease
- Farnesyl pyrophosphate synthase
- Dehydrodolichyl diphosphate synthase complex subunit nus1
- Prenyl
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups), GO:0004659 (prenyltransferase activity), GO:0004311 (farnesyltranstransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048583 (regulation of response to stimulus), GO:0048856 (anatomical structure development), GO:0023056 (positive regulation of signaling), GO:0023051 (regulation of signaling), GO:0007275 (multicellular organism development), GO:0048522 (positive regulation of cellular process), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0035295 (tube development), GO:0009967 (positive regulation of signal transduction), GO:0009790 (embryo development), GO:0010647 (positive regulation of cell communication), GO:0048513 (animal organ development), GO:0009888 (tissue development), GO:0010646 (regulation of cell communication), GO:0048731 (system development), GO:0009966 (regulation of signal transduction), GO:1902533 (positive regulation of intracellular signal transduction), GO:0048568 (embryonic organ development), GO:0060429 (epithelium development), GO:0035050 (embryonic heart tube development), GO:0072359 (circulatory system development), GO:1902531 (regulation of intracellular signal transduction), GO:0007507 (heart development), GO:0051057 (positive regulation of small GTPase mediated signal transduction), GO:0051056 (regulation of small GTPase mediated signal transduction), GO:0046579 (positive regulation of Ras protein signal transduction), GO:0046578 (regulation of Ras protein signal transduction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0140535 (intracellular protein-containing complex), GO:1990234 (transferase complex)