Protein: non-specific serine/threonine protein kinase (F1QUT2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell projection, cilium. Cytoplasm, cytoskeleton. Nucleus
Sequence: MNRYTTLKQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWEECMNLREVKSLKKLNHANVVKLKEVIRENDHLYFVFEYMKENLYQLMKDRENKMFTENEIRNIMFQVLSGLAFVHKHGFFHRDMKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRWYRAPEVLLRSPVYSSPIDIWAVGCIMAELYTLRPLFPGNSEVDEIFKICQVLGTVKKSDWPEGHQLASAMNFRFPQCVPTPLKTLIPNATNEALDIMRDLLQWDPKKRPSAVKALRYPYFQVGQLLGPRPMTPDARKAPVKAVLPSELRSEMQSVSEPVLPSQTKGQSRNSHQPLQQIPLPQSLTQTDTVALHTQKVVGGENSLMGLKNGRRRWGQTNMKPSDSWDDSDCSDTAASLSKKPSKGPEEEKTTPQPKEQKPLYTFSTVTKLPNTSRLNQSDSSHQSTSSARQHYLRQSRYMPGLISKNTQSLGSKESQQDFWDTSALMSKPLAPIGGAPMSRISPGNFVTTTYNLSGGYIPSFQKKEVGSVGQRIQLAPLGHQHALDLSATADCKTGKAKPSKSKPSSTVSVNDNSEDYDGWKRRAERTQLKGTSYSALGKNSANLITHAPSVQPVHGRIDWAAKYGSHR
InterPro domains: - IPR008271: Serine/threonine-protein kinase, active site (active_site) [122-134]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [1-286]
- IPR017441: Protein kinase, ATP binding site (binding_site) [10-33]
- IPR000719: Protein kinase domain (domain) [4-285]
- IPR050117: Mitogen-activated protein (MAP) kinase (family) [3-347]
Interaction partners: - DNA replication licensing factor MCM2
- Chromatin licensing and DNA replication factor 1
- Origin recognition complex subunit 3
- Origin recognition complex subunit 4
- DNA replication licensing factor MCM4
- Origin recognition complex subunit 5
- DNA helicase MCM9
- Origin recognition complex subunit 1
- DNA replication licensing factor MCM3
- DNA replication licensing factor MCM3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050794 (regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0044087 (regulation of cellular component biogenesis), GO:0031344 (regulation of cell projection organization), GO:1902115 (regulation of organelle assembly), GO:0033043 (regulation of organelle organization), GO:0060491 (regulation of cell projection assembly), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:1902017 (regulation of cilium assembly), GO:0120032 (regulation of plasma membrane bounded cell projection assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0005930 (axoneme), GO:0005737 (cytoplasm), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0099568 (cytoplasmic region), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0005929 (cilium), GO:0032838 (plasma membrane bounded cell projection cytoplasm), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0097014 (ciliary plasm)