Protein: RE18408p (Q7YU35)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Sequence: MTVSYAGEVPNGSSFGCFWKILWKWRGSVYKLIWRELVAYLCLYYTINVIYRFGLTESQQAIFKKIRLYFGQQSESIPMSFVLGFYVNLVVKRWWEQYRLLPWPDTLALFISAAIPNSNGGVNNETGRLMRRNIMRYMVLAYVITLQRISLRVKRRFPTTQHLVDAGLMHESEMKIFEALNQKSPMSKYWMPLVWATNIINRARKDGLIASDHIVQTILVELSDIRRRLGGLIGYDTVCVPLVYTQVVTLVLYTYFIAALLGRQMLPNVLDRSGREDPDLFFPLFTVLQFVFYVGWLKVAEVLINPFGEDDGDIELNWLIDRHIKAAYMIVDEMHEEHPELLRDQYWECVVPKDLPYTVASEHYRKDEPKGSAEKYKVKKEDAMYANIMPGGGKRMLSDDVYADYESVDTPMVERRKNNWLVRQLSRMGSMRSQSTAYSSGGMPFNRNRLNSVYSSPESGLPLTILQQQQLQQAHQQQQAGSQPSKSSLYGKFVHRKSLRAQRQLIKQNSKLNGLNVNVAKTRPRIPTPEVAKDGNTNPATSSVLMAPQQLSTTSAPPGMYPSSYAPDTLLHQESGQVLGTLLLSPIKEMDSSSSNNTLIPGHPATAALAASMKEGFTPSSIPAATNITTLSFPFSVTSTGGETMPTGTLSILPISANAQLPTITTTASGYDPNDVITTIPVSLSIQRSPSALSIVELTGADVQDGYSNSGSSNGNGGITTTALLSVKPLNGNQNISRNNSFNLSLNLQDPQQRSSMRSAGPTGTVDNSGTMPIPQRSGGLETGEVGGSSAPSTLAKHKPEQKTGEVYV
InterPro domains: - IPR021134: Bestrophin-like (family) [1-333]
- IPR000615: Bestrophin (family) [1-512]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0008509 (monoatomic anion transmembrane transporter activity), GO:0015108 (chloride transmembrane transporter activity), GO:0015103 (inorganic anion transmembrane transporter activity), GO:0015267 (channel activity), GO:0005253 (monoatomic anion channel activity), GO:0005254 (chloride channel activity), GO:0061778 (intracellular chloride channel activity), GO:0005229 (intracellular calcium activated chloride channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0042592 (homeostatic process), GO:0051234 (establishment of localization), GO:0048878 (chemical homeostasis), GO:0065008 (regulation of biological quality), GO:0071840 (cellular component organization or biogenesis), GO:0019725 (cellular homeostasis), GO:0006884 (cell volume homeostasis), GO:0055082 (intracellular chemical homeostasis), GO:0016043 (cellular component organization), GO:0090066 (regulation of anatomical structure size), GO:0030104 (water homeostasis), GO:0006810 (transport), GO:0032535 (regulation of cellular component size), GO:0009992 (intracellular water homeostasis), GO:0006811 (monoatomic ion transport), GO:0015698 (inorganic anion transport), GO:0006821 (chloride transport), GO:0008361 (regulation of cell size), GO:0006820 (monoatomic anion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0042579 (microbody), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005777 (peroxisome)