Protein: Calcium-transporting ATPase (EC 7.2.2.10) (Q95XP5)
Organism: Caenorhabditis elegans
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane {ECO:0000256|RuleBase:RU361146}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU361146}.
Sequence: MPEYGASLEELRALMEYRSAEAKEKIETDYGGTTGLCERLKTDPNNGLPNNEEELERRRNVFGANEIPPHPPKCFLQLVWEALQDVTLVILLVSAIVSLALSFYRPPGEDTAGSDDSEHDAGWIEGVAILISVIVVVLVTALNDYTKERQFRGLQAKIETEHRFFVLRGGQSVQVVVNELVVGDIAQIKYGDLIPSDGIIIQSNDLKMDESSLTGESDQIRKSPEHDPIILSGTHVMEGSGKMLVTAVGVNSQTGIIMTLLGAAKTVAEEERKTAKREGGDGASGAEEGTAQALLDSKGDEAMANGKAVAAAESDGKKERSVLQAKLTRLAIQIGYAGSFVAGCTVLILIIRFCISRYAIDGKSFSLADFQHFINFLIIGVTVLVVAVPEGLPLAVTLSLAYSVKKMMLDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSFVNDVHYKDTPKIESLDQNTAKLMMDCISINSSYSSQVIPPKQLGEQATQLGNKTECGMLGFVLALGKSYQEIRDRHPEETIPKVYTFNSVRKSMSTVINLPDGGYRVFSKGASEIVTKRCKYFLGKNGTLTKFSSKDAENLVRDVIEPMASDGLRTICVAYKDYVPSSKKTADNQIAYSSEPDWENEEMIVGDMTAIAVLGIQDPVRPEVPAAITRCQEAGITVRMVTGDNINTARSIATACGILKPGEDFIALEGKEFNARIRDENGEVSQEKLDLIWPKLRVLARAQPSDKYVLVKGIIDSRVTDSREVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSIAKFLQFQLTVNVVAVVVAFVGACAIQDTPLKAVQMLWVNLIMDTLASLALATEMPTEELLKRKPYGRTSPLISRTMCKNILGHAVYQLVILFTLIFYGEVCFNIPSGRWAPLHSPPSKHFTIVFNTFVMMTLFNEINARKIHGERNIFKGLFSNPIYYVIWIATMISQVVIIQFGGRWFSTSALNTTEWLWCLAFGVGTLLWGQIVTSIPTGSLPANMTIGSGEAPTNDPLMPDYEDSDTHEKRSGQILWVRGLTRLQTQLRVVKAFRSSLEEFDERRSIASTHSVQSMRGGFWSGGGRHTTTAASPEPAGQRIAMAAITHRQSPQPYPYYHHQQPRTPSPQPHIVVENGTSSGNNGQAATAAAAAPKAETNGKTEKVPLVQQWSPDTNSSYTQTQRSINKSMSLDTPVSVAHV
InterPro domains: - IPR008250: P-type ATPase, A domain superfamily (homologous_superfamily) [163-260]
- IPR001757: P-type ATPase (family) [353-843]
- IPR023299: P-type ATPase, cytoplasmic domain N (homologous_superfamily) [436-658]
- IPR036412: HAD-like superfamily (homologous_superfamily) [429-867]
- IPR044492: P-type ATPase, haloacid dehalogenase domain (domain) [412-815]
- IPR018303: P-type ATPase, phosphorylation site (ptm) [432-438]
- IPR006408: P-type ATPase, subfamily IIB (family) [287-1031]
- IPR023214: HAD superfamily (homologous_superfamily) [652-779]
- IPR006068: Cation-transporting P-type ATPase, C-terminal (domain) [848-1027]
- IPR022141: Plasma membrane calcium transporting P-type ATPase, C-terminal (domain) [1066-1108]
- IPR004014: Cation-transporting P-type ATPase, N-terminal (domain) [29-103]
- IPR023298: P-type ATPase, transmembrane domain superfamily (homologous_superfamily) [31-1030]
Interaction partners: - Plasma membrane calcium-transporting ATPase mca-1
- Calcium-transporting ATPase
- Calcium-transporting ATPase
- Calcium-transporting ATPase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0140657 (ATP-dependent activity), GO:0042626 (ATPase-coupled transmembrane transporter activity), GO:0022857 (transmembrane transporter activity), GO:0140358 (P-type transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0019829 (ATPase-coupled monoatomic cation transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0015399 (primary active transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0015662 (P-type ion transporter activity), GO:0005388 (P-type calcium transporter activity), GO:0022853 (active monoatomic ion transmembrane transporter activity), GO:0015085 (calcium ion transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0046873 (metal ion transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0065008 (regulation of biological quality), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0032879 (regulation of localization), GO:0040017 (positive regulation of locomotion), GO:0050794 (regulation of cellular process), GO:0051234 (establishment of localization), GO:0045927 (positive regulation of growth), GO:0051050 (positive regulation of transport), GO:0040008 (regulation of growth), GO:0040012 (regulation of locomotion), GO:0009791 (post-embryonic development), GO:0048522 (positive regulation of cellular process), GO:0040009 (regulation of growth rate), GO:0051049 (regulation of transport), GO:0006810 (transport), GO:0051481 (negative regulation of cytosolic calcium ion concentration), GO:0009790 (embryo development), GO:0060627 (regulation of vesicle-mediated transport), GO:0002164 (larval development), GO:0051130 (positive regulation of cellular component organization), GO:0040010 (positive regulation of growth rate), GO:0045807 (positive regulation of endocytosis), GO:0051128 (regulation of cellular component organization), GO:0030100 (regulation of endocytosis), GO:0071702 (organic substance transport), GO:0016192 (vesicle-mediated transport), GO:0002119 (nematode larval development), GO:0006811 (monoatomic ion transport), GO:0009792 (embryo development ending in birth or egg hatching), GO:0006812 (monoatomic cation transport), GO:0006897 (endocytosis), GO:0006816 (calcium ion transport), GO:0030001 (metal ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)