Protein: Cytochrome P450, family 17, subfamily A, polypeptide 1 (A0A8M1PIC7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane
Sequence: MAEALILPWLLCLSLFSAVTLAALYLKQKMNGFVPAGNRSPPSLPSLPIIGSLMSLVSDSPPHIFFQDLQKKYGDLYSLMMGSHKLLIVNNHHHAKEILIKKGKIFAGRPRTVTTDLLTRDGKDIAFADYSSTWKFHRKMVHGALCMFGEGSVSIEKIICREASSMCEVLTESQNSAVDLGPELTRAVTNVVCALCFNSSYKRGDAEFESMLQYSQGIVDTVAKDSLVDIFPWLQIFPNKDLRILRQCISIRDKLLQKKYEEHKVTYSDNVQRDLLDALLRAKRSSENNNSSTRDVGLTEDHVLMTVGDIFGAGVETTTTVLKWSIAYLVHNPQVQRKIQEELDSKIGKERHPQLSDRGNLPYLEATIREVLRIRPVSPLLIPHVALQDSSVGEYTVQKGTRVVINLWSLHHDEKEWKNPELFDPGRFLNEEGDGLCCPSGSYLPFGAGVRVCLGEALAKMELFLFLAWILQRFTLEMPTGQPLPDLQGKFGVVLQPKKFKVVAKVRADWEKSPLMQHC
InterPro domains: - IPR017972: Cytochrome P450, conserved site (conserved_site) [446-455]
- IPR036396: Cytochrome P450 superfamily (homologous_superfamily) [39-507]
- IPR001128: Cytochrome P450 (family) [41-502]
- IPR002401: Cytochrome P450, E-class, group I (family) [70-476]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016491 (oxidoreductase activity), GO:0016830 (carbon-carbon lyase activity), GO:0004497 (monooxygenase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016229 (steroid dehydrogenase activity), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor), GO:0016832 (aldehyde-lyase activity), GO:0008395 (steroid hydroxylase activity), GO:0033764 (steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065008 (regulation of biological quality), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0008207 (C21-steroid hormone metabolic process), GO:0044281 (small molecule metabolic process), GO:0042445 (hormone metabolic process), GO:0071704 (organic substance metabolic process), GO:0003006 (developmental process involved in reproduction), GO:0044238 (primary metabolic process), GO:0042180 (cellular ketone metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0120254 (olefinic compound metabolic process), GO:0030238 (male sex determination), GO:0044249 (cellular biosynthetic process), GO:0010817 (regulation of hormone levels), GO:0007530 (sex determination), GO:0042448 (progesterone metabolic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0120255 (olefinic compound biosynthetic process), GO:0008202 (steroid metabolic process), GO:0042181 (ketone biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0006694 (steroid biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)