Protein: Polyadenylate-binding protein (PABP) (B2RXY9)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU362004}.
Sequence: MDTGGHGCSLSSLYVGDLHPDVTESMLYEMFSPIGNILSIRVCRDVATRRSLGYAYINFQQPADAERALDTMNFEVIKGQPIRIMWSHRDPGLRKSGMGNIFIKNLENSIDNKALYDTFSTFGSILSSKVVYNEHGSRGFGFVHFETHEAAQKAINTMNGMLLNDRKVFVGHFKSRQKREAELGARALGFTNIYVKNLHANVDEQRLQDLFSQFGNMQSVKVMRDSNGQSRGFGFVNFEKHEEAQKAVDHMNGKEVSGQLLYVGRAQKRAERQSELKRRFEQMKQERQNRYQGVNLYVKNLDDSINDERLKEVFSTYGVITSAKVMTESSHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYRRRPSHPVLSSFQQPTSYLLPAVPQSTAQAVYYSSGSITPMQPDPRWTAQPHGPPSTCPPAASVVQPLSTTQHPCIHLSGASQVSSQVPHTQRVVNIGTQTTGPGGEGSSIPGQLLVPHRGTSAVHSAHGVQESAVYVPGHQPLTVSMLAAAPLHEQKQMIGERLYSLIHDACAPLTGKITGMLLELDNLELLLLLESPESLHAKIEEAVAVLQVHREMESTDRN
InterPro domains: - IPR035979: RNA-binding domain superfamily (homologous_superfamily) [12-374]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [9-383]
- IPR006515: Polyadenylate binding protein, human types 1, 2, 3, 4 (family) [11-596]
- IPR045305: PABP, RNA recognition motif 2 (domain) [97-172]
- IPR002004: Polyadenylate-binding protein/Hyperplastic disc protein, C-terminal (domain) [523-600]
- IPR034364: PABP, RNA recognition motif 1 (domain) [12-91]
- IPR036053: PABC (PABP) domain (homologous_superfamily) [478-601]
- IPR000504: RNA recognition motif domain (domain) [11-370]
- IPR003954: RNA recognition motif domain, eukaryotic-type (domain) [12-366]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003727 (single-stranded RNA binding), GO:0070717 (poly-purine tract binding), GO:0008143 (poly(A) binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0051640 (organelle localization), GO:0044237 (cellular metabolic process), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0019222 (regulation of metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0009893 (positive regulation of metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0021700 (developmental maturation), GO:0071704 (organic substance metabolic process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0044238 (primary metabolic process), GO:0007276 (gamete generation), GO:0007281 (germ cell development), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0046483 (heterocycle metabolic process), GO:0048469 (cell maturation), GO:0060255 (regulation of macromolecule metabolic process), GO:0016043 (cellular component organization), GO:0009994 (oocyte differentiation), GO:0006725 (cellular aromatic compound metabolic process), GO:0001556 (oocyte maturation), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0051647 (nucleus localization), GO:0071695 (anatomical structure maturation), GO:0007292 (female gamete generation), GO:0090304 (nucleic acid metabolic process), GO:0048599 (oocyte development), GO:0048477 (oogenesis), GO:0006325 (chromatin organization), GO:0010628 (positive regulation of gene expression), GO:0010467 (gene expression), GO:0010468 (regulation of gene expression), GO:0040029 (epigenetic regulation of gene expression), GO:0006338 (chromatin remodeling), GO:0016070 (RNA metabolic process), GO:0045815 (transcription initiation-coupled chromatin remodeling), GO:0006396 (RNA processing), GO:0006397 (mRNA processing), GO:0016071 (mRNA metabolic process), GO:0031123 (RNA 3'-end processing), GO:0043631 (RNA polyadenylation), GO:0006378 (mRNA polyadenylation), GO:0031124 (mRNA 3'-end processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)