wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Histone H2B type 1-D (H2B-clustered histone 5) (HIRA-interacting protein 2) (Histone H2B.1 B) (Histone H2B.b) (H2B/b) (P58876)
Organism: Homo sapiens (Human)
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Subcellular location: Nucleus. Chromosome.
Sequence: MPEPTKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
InterPro domains: - IPR009072: Histone-fold (homologous_superfamily) [1-126]
- IPR055333: Histone H2B, conserved site (conserved_site) [93-115]
- IPR000558: Histone H2B (family) [9-124]
- IPR007125: Histone H2A/H2B/H3 (domain) [11-101]
Interaction partners: - Histone H2A type 1-C
- Histone H4
- Histone H3.2
- Histone H3-like centromeric protein A
- Histone H2A type 1-D
- Histone H2A.J
- Histone H2B type 1-H
- Histone H2A type 1-B/E
- Histone H2A type 2-A
- Histone H2B type 1-C/E/F/G/I
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0002376 (immune system process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0006950 (response to stress), GO:0051707 (response to other organism), GO:0006955 (immune response), GO:0009607 (response to biotic stimulus), GO:0006952 (defense response), GO:0043207 (response to external biotic stimulus), GO:0002251 (organ or tissue specific immune response), GO:0045087 (innate immune response), GO:0006959 (humoral immune response), GO:0098542 (defense response to other organism), GO:0019730 (antimicrobial humoral response), GO:0002385 (mucosal immune response), GO:0061844 (antimicrobial humoral immune response mediated by antimicrobial peptide)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005615 (extracellular space), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0005576 (extracellular region), GO:0043230 (extracellular organelle), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0070062 (extracellular exosome), GO:0043227 (membrane-bounded organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:1903561 (extracellular vesicle), GO:0005634 (nucleus)
Protein: Flagellar hook-associated protein 1 (HAP1) (P0A1J5)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function: Not known
Subcellular location: Secreted {ECO:0000250}. Bacterial flagellum {ECO:0000250}.
Sequence: MSSLINHAMSGLNAAQAALNTVSNNINNYNVAGYTRQTTILAQANSTLGAGGWIGNGVYVSGVQREYDAFITNQLRGAQNQSSGLTTRYEQMSKIDNLLADKSSSLSGSLQSFFTSLQTLVSNAEDPAARQALIGKAEGLVNQFKTTDQYLRDQDKQVNIAIGSSVAQINNYAKQIANLNDQISRMTGVGAGASPNDLLDQRDQLVSELNKIVGVEVSVQDGGTYNLTMANGYTLVQGSTARQLAAVPSSADPTRTTVAYVDEAAGNIEIPEKLLNTGSLGGLLTFRSQDLDQTRNTLGQLALAFADAFNAQHTKGYDADGNKGKDFFSIGSPVVYSNSNNADKTVSLTAKVVDSTKVQATDYKIVFDGTDWQVTRTADNTTFTATKDADGKLEIDGLKVTVGTGAQKNDSFLLKPVSNAIVDMNVKVTNEAEIAMASESKLDPDVDTGDSDNRNGQALLDLQNSNVVGGNKTFNDAYATLVSDVGNKTSTLKTSSTTQANVVKQLYKQQQSVSGVNLDEEYGNLQRYQQYYLANAQVLQTANALFDALLNIR
InterPro domains: - IPR049119: Flagellar hook-associated protein 1, D2-like domain (domain) [336-416]
- IPR010930: Flagellar basal-body/hook protein, C-terminal domain (domain) [512-552]
- IPR001444: Flagellar basal body rod protein, N-terminal (domain) [5-35]
- IPR019776: Flagellar basal body rod protein, conserved site (conserved_site) [11-31]
- IPR002371: Flagellar hook-associated protein 1 (family) [1-552]
- IPR053927: Flagellar hook-associated protein FlgK, helical domain (domain) [92-328]
Interaction partners: - Flagellar basal-body rod protein FlgC
- Flagellar basal-body rod protein FlgG
- Flagellar hook-associated protein 2
- Flagellar secretion chaperone FliS
- Peptidoglycan hydrolase FlgJ
- Flagellar basal body rod protein FlgB
- Flagellar hook protein FlgE
- Flagellar hook-associated protein 3
- Basal-body rod modification protein FlgD
- Flagella synthesis protein FlgN
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0006996 (organelle organization), GO:0022607 (cellular component assembly), GO:0030030 (cell projection organization), GO:0070925 (organelle assembly), GO:0030031 (cell projection assembly), GO:0044781 (bacterial-type flagellum organization), GO:0044780 (bacterial-type flagellum assembly), GO:0140694 (non-membrane-bounded organelle assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0043228 (non-membrane-bounded organelle)
Protein: LD22578p (Q8MZ45)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000256|ARBA:ARBA00004120}.
Sequence: MGIRQLFMDIEGTKVIFIDDHSQGYVFLPVVEEALLIPDIPKQCLGCLWDLTQPNIFISYDARIVNTHVFVRHSVQGTHTLMVGESKLNPGQFPLLLCGGEMALHIDGGQYATQSLSTHVVNPSNSQAANLQMLLKLRNYDEAYKLCKQMNQSSAWREFGEQAISDLEPDIAIRAYRQLGDAALVNALSELRYVEDLDMLIGCCCTLLAQYDQAKEHMLKGVYTRAALDLCRDLLQWDQALLLAHKNDPQEVPYIAREYAQQLEFNGNYTDALYHYEKGYKEDLINSKETETDALMDSSPEYEEHVRLCKMGIARTSIRAGDFRRGIQYAVELEDQQLLFDCAELLATVGHLTEAAGLYERGGFYDEACGHYIALKMWNKANNILPKVKSTKLHAAYAKAKENDGHYEEAIRSYRIAGDLDACVRIYLDHLCDPHAASEIVLESRSMDSAKLLAKFYQKIGDVEQALQFLVICGCVEEAFALAQRHNKLRRHGELLERYENAKSSDYLALAHYFEGEKYTLLAGKYYFLAREFTKALRFLLKASAFNNEEQVSLSLAIDCVATSNNEQLATQLIEFLLGEVDGVPKDPRYLFRLYMARKHYKDAAKTAVIIANQEQIAGNYKSARDLLYSMYQELRRNNLSVTAEMRHQFILLHRYTLVRIHVKLGNHLLAAKLLVQVAACISQFPEHIIPILTSTVIECHRAGLKKSAFTYASTLMRPDYRNQLDPRYAKKIESIVRKAPKGIKQLRDEIDGETMECPICDSNLANMEVTCYSCKTTLPICIATGQHIIKQLMTSCPQCDFLCFRAEMENILSENGECPMCGENVAPEQLLDVEDIRPYILAAS
InterPro domains: - IPR040379: WD repeat-containing protein 19/dyf-2 (family) [2-841]
- IPR056170: IFT121-like, zinc finger domain (domain) [780-824]
- IPR039468: WDR19, WD40 repeat domain (domain) [1-119]
- IPR056168: IF140/IFT172/WDR19, TPR domain (domain) [139-557]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0071840 (cellular component organization or biogenesis), GO:0051649 (establishment of localization in cell), GO:0016043 (cellular component organization), GO:0046907 (intracellular transport), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport), GO:0016197 (endosomal transport), GO:0006996 (organelle organization), GO:0010256 (endomembrane system organization), GO:0061024 (membrane organization), GO:0016050 (vesicle organization), GO:0048193 (Golgi vesicle transport), GO:0048284 (organelle fusion), GO:0061025 (membrane fusion), GO:0006897 (endocytosis), GO:0007032 (endosome organization), GO:0006906 (vesicle fusion), GO:0090174 (organelle membrane fusion), GO:0034058 (endosomal vesicle fusion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0043227 (membrane-bounded organelle), GO:0120025 (plasma membrane bounded cell projection), GO:0005929 (cilium), GO:0097730 (non-motile cilium)
Protein: Modulator of FtsH protease YccA (P0AAC6)
Organism: Escherichia coli (strain K12)
Function: Negatively modulates the activity of the FtsH protease for membrane substrates. Overexpression or stabilizing YccA counteracts the FtsH-mediated degradation of SecY when the SecYEG preprotein translocator is jammed.
Subcellular location: Cell inner membrane; Multi-pass membrane protein. Note=There are conflicting results regarding the localization of the C-terminus of this protein: According to a report, the C-terminus localizes in the periplasm (PubMed:10357810). Another report gives the C-terminus in the cytoplasm (PubMed:15919996). We show the periplasmic location. {ECO:0000269|PubMed:10357810, ECO:0000269|PubMed:15919996}.
Sequence: MDRIVSSSHDRTSLLSTHKVLRNTYFLLSLTLAFSAITATASTVLMLPSPGLILTLVGMYGLMFLTYKTANKPTGIISAFAFTGFLGYILGPILNTYLSAGMGDVIAMALGGTALVFFCCSAYVLTTRKDMSFLGGMLMAGIVVVLIGMVANIFLQLPALHLAISAVFILISSGAILFETSNIIHGGETNYIRATVSLYVSLYNIFVSLLSILGFASRD
InterPro domains: - IPR006213: Bax inhibitor 1, conserved site (conserved_site) [87-117]
- IPR006214: Bax inhibitor 1-related (family) [19-214]
Interaction partners: - Sulfurtransferase TusE
- Protease HtpX
- ATP-dependent zinc metalloprotease FtsH
- Uncharacterized protein YbhM
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0033554 (cellular response to stress), GO:0006974 (cellular response to DNA damage stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Putative melanocortin 2 receptor (A7Y4C2)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Sequence: MNDVSALPSNHTDCQVVKVPHLVFLVLGMVSLSENLLVVVAVVRNKNLHSPMYMFICSLATFNTISSLSKTWETLMMEFSDVGQLDSRGDSVRRVDDIIDALLCMSFIGCICSFLAIAVDRYVTIFHALRYHNIMTTRRAAAALAGIWALCGVAGAVMVAFCDATVIKIFFIVLFLISLLLILFLYVHMFLLARSHARKIAALPGSAMPHRSLRGALTLTMLFGVFVVCWAPFFLHLLLLMVCVENPYCECYRSLFQLNLVLLMSHAVVDPAIYAFRSAELRNTFRKMLFCSDSPLCYKVKALFH
InterPro domains: - IPR001908: Melanocortin receptor 3-5 (family) [172-262]
- IPR001671: Melanocortin/ACTH receptor (family) [44-291]
- IPR017452: GPCR, rhodopsin-like, 7TM (domain) [34-274]
- IPR000276: G protein-coupled receptor, rhodopsin-like (family) [19-289]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0033218 (amide binding), GO:0042562 (hormone binding), GO:0017046 (peptide hormone binding), GO:0042277 (peptide binding), GO:0004888 (transmembrane signaling receptor activity), GO:0001653 (peptide receptor activity), GO:0008528 (G protein-coupled peptide receptor activity), GO:0004930 (G protein-coupled receptor activity), GO:0008188 (neuropeptide receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0071495 (cellular response to endogenous stimulus), GO:0009755 (hormone-mediated signaling pathway), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0070887 (cellular response to chemical stimulus), GO:0007186 (G protein-coupled receptor signaling pathway), GO:0032870 (cellular response to hormone stimulus), GO:0071310 (cellular response to organic substance)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Probable electron transfer flavoprotein subunit alpha, mitochondrial (Alpha-ETF) (P78790)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).
Subcellular location: Mitochondrion matrix {ECO:0000250}.
Sequence: MLRTTSRTFSRALSSSNFKINCGRRHWFSVLTLLEHQGGNLSPASLSAVEAAKRTGGDVFGFVIGKDSSQISQKVAKSVNDLKKVIYVENPSYEHNIPDQIANVLFENVKKNEISHVFSAHSTVGKGVMPRLAAMFDVMQISDIIGVVSADTFVRPTYAGNVNVTVSTKDPIKIVTVRASAFDAAPSSGEGAATVVEGIDPKPAALQEWVSENIIKNARPDLSSAERVVAGGRPLKDKETFERILTPLADKLGAAIGATRVAVDSGYADNSLQIGQTGKIIAPKLYIAVGIDGAIQHLAGIKDSKVIAAINRDENAPIFQTADVGIVGDLFEIVPELTEKL
InterPro domains: - IPR014731: Electron transfer flavoprotein, alpha subunit, C-terminal (domain) [221-302]
- IPR029035: DHS-like NAD/FAD-binding domain superfamily (homologous_superfamily) [220-341]
- IPR033947: Electron transfer flavoprotein, alpha subunit, N-terminal (domain) [29-197]
- IPR018206: Electron transfer flavoprotein subunit alpha, conserved site (conserved_site) [285-311]
- IPR001308: Electron transfer flavoprotein alpha subunit/FixB (family) [26-341]
- IPR014729: Rossmann-like alpha/beta/alpha sandwich fold (homologous_superfamily) [28-214]
- IPR014730: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal (domain) [30-213]
Interaction partners: - Probable electron transfer flavoprotein subunit beta
- Secretory component protein psh3
- Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial
- Acetyl-CoA acetyltransferase
- Succinate--CoA ligase subunit alpha, mitochondrial
- Putative acyl carrier protein, mitochondrial
- Succinate dehydrogenase iron-sulfur subunit, mitochondrial
- Probable NADPH:adrenodoxin oxidoreductase, mitochondrial
- ATP synthase subunit alpha
- Uncharacterized protein C14C4.04
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0009055 (electron transfer activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006091 (generation of precursor metabolites and energy), GO:0015980 (energy derivation by oxidation of organic compounds), GO:0045333 (cellular respiration), GO:0009060 (aerobic respiration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Proteasome activator complex subunit 3 (Activator of multicatalytic protease subunit 3) (Proteasome activator 28 subunit gamma) (K7ENH2)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MASLLKVDQEVKLKVDSFRERITSEAEDLVANFFPKKLLELDSFLKEPILNIHDLTQIHSDMNLPVPDPILLTNSHDGLDGPTYKKRRLDECEEAFQGTKVFVMPNGMLKSNQQLVDIIEKVKPEIRLLIEKCNTEETVAELRTVESEAASYLDQISRYYITRAKLVSKIAKYPHVEDY
InterPro domains: - IPR003185: Proteasome activator PA28, N-terminal domain (domain) [10-69]
- IPR003186: Proteasome activator PA28, C-terminal domain (domain) [136-179]
- IPR036997: Proteasome activator PA28, C-terminal domain superfamily (homologous_superfamily) [135-179]
- IPR036252: Proteasome activator superfamily (homologous_superfamily) [5-179]
- IPR009077: Proteasome activator PA28 (family) [4-135]
- IPR036996: Proteasome activator PA28, N-terminal domain superfamily (homologous_superfamily) [5-64]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051052 (regulation of DNA metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0006275 (regulation of DNA replication), GO:0090329 (regulation of DNA-templated DNA replication), GO:0030174 (regulation of DNA-templated DNA replication initiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Mind the gap, isoform E (A0A0C4DHF5)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MNFFVIGFLIMQAARLACGTCVLSSDFGFILDCNFKKSGLFRVRNLGGLKAHFGLGFSLGDELGFPESLGNTESDRRRAISYKNGAPPDLVGVLPSTQQQVNPPVQHPLPEKRISSRSTGAAPYNLQQVQQQQQLQLQQQKLQQQQLQQQLKLKQLLLLQQQQQQQQQLMTEARPLPLGVPAFRPIPQKQLAATQPSAPSSTPAERRVAVDTPEPRVSVNNKLVSSIDQPHSNRTFHVANPVVSQPVAVPVFQAMPQSIARIANVGKEHRTVSSHPNYLQFEEPKFDLKDVTVEELAAAANVTVDTIKHAIYVREQQLKAEHRAQLAAKLREEFMRTSTVRTTTTTTTTTTTTPRPQKSLAEHKVSKVMNAPKEYYPVGYDKNFDDNFKSKVDLPPTSFSCAKQKHFPGLYADTDLGCMVFHVCALTDDGMVRKSFLCPENTLFDQTILKCNWWFYVDCSSSTSVYDSNIPISKSYQLMKSLTYFSKYAGGQRHEQGGDKDENALDIDSLRESMEGVARRQEQAKKAELRVEEQRSMPKEDHEHVVPAEAEQQLSN
InterPro domains: - IPR036508: Chitin binding domain superfamily (homologous_superfamily) [405-462]
- IPR002557: Chitin binding domain (domain) [398-461]
- IPR052976: Scoloptoxin-like (family) [193-530]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097367 (carbohydrate derivative binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0048731 (system development), GO:0007399 (nervous system development), GO:0034330 (cell junction organization), GO:0022607 (cellular component assembly), GO:0007416 (synapse assembly), GO:0050808 (synapse organization), GO:0034329 (cell junction assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0150034 (distal axon), GO:0044306 (neuron projection terminus), GO:0042995 (cell projection), GO:0030054 (cell junction), GO:0005615 (extracellular space), GO:0098793 (presynapse), GO:0005576 (extracellular region), GO:0120025 (plasma membrane bounded cell projection), GO:0043679 (axon terminus), GO:0045202 (synapse), GO:0043083 (synaptic cleft), GO:0043195 (terminal bouton), GO:0043005 (neuron projection), GO:0030424 (axon)
Protein: MinK-related peptide, potassium channel accessory subunit protein 4 (P34394)
Organism: Caenorhabditis elegans
Function: Not known
Sequence: MTFPKENINNYASSSFNYKYLIEEFLQWSSSCNRISYPTKYFDFLLVIIMTFVFLCLVYLLIWIEVLLNSSRPDPKHRVYYPRTNFWQRTD
InterPro domains: - IPR020383: MinK-related peptide, potassium channel accessory subunit protein 4 (family) [1-78]
Interaction partners: - BTB domain-containing protein
- MAM domain-containing protein
- BTB domain-containing protein
- MPS-3
- MiRP K channel accessory Subunit
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0002376 (immune system process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0006955 (immune response), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0045087 (innate immune response), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Homoserine dehydrogenase (HDH) (EC 1.1.1.3) (F4K6Y8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MKKIPVLLMGCGGVGRHLLQHIVSCRSLHAKMGVHIRVIGVCDSKSLVAPMDVLKEELNDELLSEVCLIKSTGSALSKLGALEKGGYRVVHDSELSTETEEIAKLLGKSTGLAVVDCSASMETIEILMKAVDLGCCIVLANKKPVTSTLEHYDKLALHPRFIRHESTVGAGLPVIASLNRIISSGDPVHRIVGSLSGTLGYVMSELEDGKPLSQVVQAAKKLGYTEPDPRDDLGGMDVARKGLILARLLGKRIIMDSIKIESLYPEEMGPGLMSVDDFLHNGIVKLDQNIEERVKKASSKGCVLRYVCVIEGSSVQVGIREVSKDSPLGRLRGSDNIVEIYSRCYKEQPLVIQGAGAGNDTTAAGVLADIIDLQDLFH
InterPro domains: - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [1-192]
- IPR001342: Homoserine dehydrogenase, catalytic (domain) [173-371]
- IPR022697: Homoserine dehydrogenase lacking ACT domain (family) [1-378]
- IPR019811: Homoserine dehydrogenase, conserved site (conserved_site) [219-241]
- IPR011147: Bifunctional aspartokinase/homoserine dehydrogenase, homoserine dehydrogenase domain (domain) [2-377]
Interaction partners: - Aspartokinase 1, chloroplastic
- Aspartokinase 3, chloroplastic
- Aspartokinase 2, chloroplastic
- Homoserine kinase
- aspartate-semialdehyde dehydrogenase
- Phosphoserine phosphatase, chloroplastic
- Homoserine kinase, putative / HSK
- Probable cystathionine gamma-synthase 2
- Cystathionine gamma-synthase 1, chloroplastic
- 4-hydroxy-tetrahydrodipicolinate synthase 2, chloroplastic
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0006970 (response to osmotic stress), GO:0001101 (response to acid chemical), GO:1901700 (response to oxygen-containing compound), GO:0009414 (response to water deprivation), GO:0010035 (response to inorganic substance), GO:0009415 (response to water), GO:0010033 (response to organic substance), GO:1902074 (response to salt), GO:0009651 (response to salt stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0043231 (intracellular membrane-bounded organelle)