Protein: Reticulon (Q4G5W2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU210713}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU210713}.
Sequence: MDDQISSTTPSYDVHHDDEGEFRAEKQANSLMDEDFSSSEAQAHVPEVEGILDLAGGAKDALERHRSTMPRKEEPLLDFGEPEPEPSSTIKPEPEAPKPAPISSFGDASPKQAKPEEKEEKPTVAPYKCNSSCSLVELLYWRDLQRTGVVFGAGLFLLLSLSMCSIISVLSYVALALLSVTVSFRIYKGILQAVQKSEDGHPFKMYLDKDTALPAEMVHKYSDSTLVHINTVIKELRRLFLVEDLVDSLKFAVLMWILTYVGALFNGLTLIILGFIGAFSCPVIYEKHQAQIDHYYGLVNKQFKDVVGKIQAKIPGAKPKTE
InterPro domains: - IPR046964: Reticulon 1-4 (family) [24-322]
- IPR003388: Reticulon (domain) [135-322]
Interaction partners: - Dehydrodolichyl diphosphate synthase complex subunit nus1
- Reticulon 4 receptor.
- Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1-B
- Oligodendrocyte myelin glycoprotein b
- Atlastin-1
- Myelin-associated glycoprotein
- Atlastin GTPase 2.
- Atlastin 3
- Receptor expression-enhancing protein.
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0009605 (response to external stimulus), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0042221 (response to chemical), GO:0042330 (taxis), GO:0071840 (cellular component organization or biogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0050794 (regulation of cellular process), GO:0040013 (negative regulation of locomotion), GO:0048523 (negative regulation of cellular process), GO:0040012 (regulation of locomotion), GO:0032989 (cellular component morphogenesis), GO:0021675 (nerve development), GO:2000145 (regulation of cell motility), GO:0001568 (blood vessel development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0000902 (cell morphogenesis), GO:0009888 (tissue development), GO:0060322 (head development), GO:0009790 (embryo development), GO:0016043 (cellular component organization), GO:0006935 (chemotaxis), GO:2000146 (negative regulation of cell motility), GO:0035239 (tube morphogenesis), GO:0048882 (lateral line development), GO:0030030 (cell projection organization), GO:0048880 (sensory system development), GO:0001944 (vasculature development), GO:0032990 (cell part morphogenesis), GO:0097485 (neuron projection guidance), GO:0007423 (sensory organ development), GO:0021545 (cranial nerve development), GO:0030334 (regulation of cell migration), GO:0061053 (somite development), GO:0048666 (neuron development), GO:0030855 (epithelial cell differentiation), GO:0030336 (negative regulation of cell migration), GO:0007420 (brain development), GO:0022008 (neurogenesis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0007399 (nervous system development), GO:0048514 (blood vessel morphogenesis), GO:0007422 (peripheral nervous system development), GO:0072359 (circulatory system development), GO:0007417 (central nervous system development), GO:0060429 (epithelium development), GO:0048858 (cell projection morphogenesis), GO:0002040 (sprouting angiogenesis), GO:0030182 (neuron differentiation), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0048925 (lateral line system development), GO:0001654 (eye development), GO:0048934 (peripheral nervous system neuron differentiation), GO:0060231 (mesenchymal to epithelial transition), GO:0021554 (optic nerve development), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0048884 (neuromast development), GO:0048935 (peripheral nervous system neuron development), GO:0150063 (visual system development), GO:0007411 (axon guidance), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0048916 (posterior lateral line development), GO:0048881 (mechanosensory lateral line system development), GO:0048915 (posterior lateral line system development), GO:0048812 (neuron projection morphogenesis), GO:0048936 (peripheral nervous system neuron axonogenesis), GO:0061564 (axon development), GO:0043010 (camera-type eye development), GO:0048919 (posterior lateral line neuromast development), GO:0007409 (axonogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)