Protein: High-affinity nitrate transporter 2.1 (AtNRT2:1) (Protein ACH1) (Protein LATERAL ROOT INITIATION 1) (O82811)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in nitrate transport, but does not seem to be able to mediate transport by its own. Acts as a dual component transporter with NTR3.1. Acts as a repressor of lateral root initiation under high sucrose/low nitrate conditions.
Subcellular location: Cell membrane {ECO:0000269|PubMed:17573350, ECO:0000269|PubMed:17583518, ECO:0000269|PubMed:19704673, ECO:0000269|PubMed:20561257}; Multi-pass membrane protein {ECO:0000269|PubMed:17573350, ECO:0000269|PubMed:17583518, ECO:0000269|PubMed:19704673, ECO:0000269|PubMed:20561257}.
Sequence: MGDSTGEPGSSMHGVTGREQSFAFSVQSPIVHTDKTAKFDLPVDTEHKATVFKLFSFAKPHMRTFHLSWISFSTCFVSTFAAAPLVPIIRENLNLTKQDIGNAGVASVSGSIFSRLVMGAVCDLLGPRYGCAFLVMLSAPTVFSMSFVSDAAGFITVRFMIGFCLATFVSCQYWMSTMFNSQIIGLVNGTAAGWGNMGGGITQLLMPIVYEIIRRCGSTAFTAWRIAFFVPGWLHIIMGILVLNLGQDLPDGNRATLEKAGEVAKDKFGKILWYAVTNYRTWIFVLLYGYSMGVELSTDNVIAEYFFDRFHLKLHTAGLIAACFGMANFFARPAGGYASDFAAKYFGMRGRLWTLWIIQTAGGLFCVWLGRANTLVTAVVAMVLFSMGAQAACGATFAIVPFVSRRALGIISGLTGAGGNFGSGLTQLLFFSTSHFTTEQGLTWMGVMIVACTLPVTLVHFPQWGSMFLPPSTDPVKGTEAHYYGSEWNEQEKQKNMHQGSLRFAENAKSEGGRRVRSAATPPENTPNNV
InterPro domains: - IPR011701: Major facilitator superfamily (family) [69-425]
- IPR036259: MFS transporter superfamily (homologous_superfamily) [56-466]
- IPR044772: Nitrate transporter (family) [4-515]
Interaction partners: - Nitrate reductase 1
- Nitrate reductase 2
- Ferredoxin--nitrite reductase, chloroplastic
- High-affinity nitrate transporter 3.1
- Protein NRT1/ PTR FAMILY 6.3
- Protein NLP7
- CBL-interacting serine/threonine-protein kinase 23
- Protein NRT1/ PTR FAMILY 7.3
- Protein NRT1/ PTR FAMILY 4.6
- Ammonium transporter 2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015103 (inorganic anion transmembrane transporter activity), GO:0015112 (nitrate transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0051234 (establishment of localization), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:0055085 (transmembrane transport), GO:1901700 (response to oxygen-containing compound), GO:0010035 (response to inorganic substance), GO:1901698 (response to nitrogen compound), GO:0070887 (cellular response to chemical stimulus), GO:0098660 (inorganic ion transmembrane transport), GO:0006810 (transport), GO:1902074 (response to salt), GO:1901699 (cellular response to nitrogen compound), GO:0010167 (response to nitrate), GO:0071705 (nitrogen compound transport), GO:0098661 (inorganic anion transmembrane transport), GO:0071241 (cellular response to inorganic substance), GO:1901701 (cellular response to oxygen-containing compound), GO:1902075 (cellular response to salt), GO:0015698 (inorganic anion transport), GO:1902025 (nitrate import), GO:0015706 (nitrate transmembrane transport), GO:1902170 (cellular response to reactive nitrogen species)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)