Protein: Tau tubulin kinase 1 (A0A0G2JTK1)
Organism: Rattus norvegicus (Rat)
Function: Not known
Sequence: MQCLAAALKDETNMSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDALLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPPILPGRPPEGLGPGPHLVPHPGGPEAEVWEETDVNRNKLRINIGKTPCVEEEQSRGVGVPSSPVRAPPDSPTTPVRSLRYRRVNSPESERLSTAADGRAELQERRSRMDLPGSPSRQACSSQPAQMLSVDTGHADRQASGRMDVSASVEQEALSNAFRSVPLAEEEDFDSKEWVIIDKETELKDFPPGAEPSTSGTTDEEPEELRPLPEEGEERRRLGTEPTVRPRGRGMQTLAEEDPRQMLPQPAPPQLSQADGRSETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQRQVFSVAPPFEVNGLPRAVPLGLPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQVPLAPFQPQANGKEGEEEEEEDEEEEEEEEEEDEEDEEEEDEEDEDEEEEEAGALGEVLGPRSGSSSEGSERSQEGAPSTLLADDQKEARGRASMADGDLEPEEGSKTLVLVSPGDMKKSPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSILKSEPKPSGPGAGVGVGLVAPGAGVTAVTSPFTKVERTFVHIAEKSHLNVMSSGGQAPRPEELSTGGELGLEMLSEVGAAEEGAPQPLENGMALVGPDGTEMESCALSGPPGETPSEVVTDSLPDGPALADEPAPASPQEPITKKGTIISPSRHAMPGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWSKRARPQQDLARLVMEKRQGRLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPAAALPRKAGRAATTRSRIPRPISVSMPAEGQQLPGRPHGAASATDSAITSRLQLQKPPGLATAADHRPKQPASRASGPGRAQVSKPAAPRSPGLPTSTARHSSGSPRSQSLSRKESSSPSHQARPGFPPSRGVLQVRSQSEASPGGPKKGPKGKQLQTLRAATKGRPAVSEGRPGNR
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [30-311]
- IPR042714: Tau-tubulin kinase 1, catalytic domain (domain) [33-294]
- IPR050235: Casein Kinase 1 Ser/Thr Protein Kinase (family) [22-762]
- IPR017441: Protein kinase, ATP binding site (binding_site) [40-63]
- IPR000719: Protein kinase domain (domain) [34-308]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0048522 (positive regulation of cellular process), GO:0032879 (regulation of localization), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0051050 (positive regulation of transport), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0051049 (regulation of transport), GO:0044085 (cellular component biogenesis), GO:0032388 (positive regulation of intracellular transport), GO:0060341 (regulation of cellular localization), GO:0019538 (protein metabolic process), GO:0016043 (cellular component organization), GO:0060627 (regulation of vesicle-mediated transport), GO:0051130 (positive regulation of cellular component organization), GO:0032886 (regulation of microtubule-based process), GO:0051128 (regulation of cellular component organization), GO:0043170 (macromolecule metabolic process), GO:0006793 (phosphorus metabolic process), GO:0036211 (protein modification process), GO:0030100 (regulation of endocytosis), GO:0043412 (macromolecule modification), GO:0030030 (cell projection organization), GO:0032355 (response to estradiol), GO:0070201 (regulation of establishment of protein localization), GO:0060632 (regulation of microtubule-based movement), GO:0033043 (regulation of organelle organization), GO:0006796 (phosphate-containing compound metabolic process), GO:0032880 (regulation of protein localization), GO:0006996 (organelle organization), GO:0010638 (positive regulation of organelle organization), GO:1905477 (positive regulation of protein localization to membrane), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:1900242 (regulation of synaptic vesicle endocytosis), GO:0051493 (regulation of cytoskeleton organization), GO:0030031 (cell projection assembly), GO:1903747 (regulation of establishment of protein localization to mitochondrion), GO:0006468 (protein phosphorylation), GO:0120036 (plasma membrane bounded cell projection organization), GO:0044782 (cilium organization), GO:0018193 (peptidyl-amino acid modification), GO:0120031 (plasma membrane bounded cell projection assembly), GO:0018105 (peptidyl-serine phosphorylation), GO:0060271 (cilium assembly), GO:0018209 (peptidyl-serine modification)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0150034 (distal axon), GO:0042995 (cell projection), GO:0044297 (cell body), GO:0030427 (site of polarized growth), GO:0036477 (somatodendritic compartment), GO:0048471 (perinuclear region of cytoplasm), GO:0005737 (cytoplasm), GO:0043025 (neuronal cell body), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0030426 (growth cone), GO:0043227 (membrane-bounded organelle), GO:0043005 (neuron projection), GO:0043231 (intracellular membrane-bounded organelle), GO:0030424 (axon), GO:0005634 (nucleus)