Protein: Mitogen-activated protein kinase (EC 2.7.11.24) (Q23993)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MSVSMSLVQGGAAGGAPQGASAILAAAAPYYQPPAVPQDVQPDRPIGYGAFGVVWAVTDPRDGRRVALKKLPNVFQSLVSSKRVFRELKMLCFFKHENVLSALDILQPPHLDFFQEIYVITELLQSDLHKIIVSPQHLSADHIKVFLYQILRGLKYLHSARILHRDIKPGNLLVNSNCVLKICDFGLARVEEPDQAKHMTQEVVTQYYRAPEILMGARHYSSAVDVWSVGCIFGELLGRRILFQAQNPVQQLELITELLGTPTMEDMRHACEGARTHMLRRAPKPPSFSVLYTLSSHATHEAVHLLCQMLVFDPDKRISVTDALAHPYLDEGRLRYHSCMCKCCFTTSAGMRQYTADFEPSAGQPFDDLWERKLTSVQQVKEEMHKFIAEQLQTGRVPLCINPQSAAFKSFGQPMRMRKSTTTTTTTTTTTTCTAAPAAAPIRRRLLLRCPREPIQVQIEILGARSPLTRTTRYRHA
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [42-332]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [162-174]
- IPR050117: Mitogen-activated protein (MAP) kinase (family) [43-370]
- IPR003527: Mitogen-activated protein (MAP) kinase, conserved site (conserved_site) [75-178]
- IPR017441: Protein kinase, ATP binding site (binding_site) [46-69]
- IPR000719: Protein kinase domain (domain) [40-329]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0040011 (locomotion), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0007163 (establishment or maintenance of cell polarity), GO:0042330 (taxis), GO:0051240 (positive regulation of multicellular organismal process), GO:0007389 (pattern specification process), GO:0006807 (nitrogen compound metabolic process), GO:0051239 (regulation of multicellular organismal process), GO:0071704 (organic substance metabolic process), GO:0045927 (positive regulation of growth), GO:0009791 (post-embryonic development), GO:0050793 (regulation of developmental process), GO:0065008 (regulation of biological quality), GO:0044237 (cellular metabolic process), GO:0050794 (regulation of cellular process), GO:0044238 (primary metabolic process), GO:0051094 (positive regulation of developmental process), GO:0040008 (regulation of growth), GO:0048522 (positive regulation of cellular process), GO:0048639 (positive regulation of developmental growth), GO:0048736 (appendage development), GO:0002165 (instar larval or pupal development), GO:0042067 (establishment of ommatidial planar polarity), GO:0007552 (metamorphosis), GO:0048729 (tissue morphogenesis), GO:1901564 (organonitrogen compound metabolic process), GO:0048731 (system development), GO:0019538 (protein metabolic process), GO:0048513 (animal organ development), GO:0050803 (regulation of synapse structure or activity), GO:0051130 (positive regulation of cellular component organization), GO:0035107 (appendage morphogenesis), GO:0042332 (gravitaxis), GO:0044089 (positive regulation of cellular component biogenesis), GO:0043170 (macromolecule metabolic process), GO:0044087 (regulation of cellular component biogenesis), GO:0006793 (phosphorus metabolic process), GO:0009887 (animal organ morphogenesis), GO:2000026 (regulation of multicellular organismal development), GO:0009888 (tissue development), GO:0003002 (regionalization), GO:0009629 (response to gravity), GO:0007164 (establishment of tissue polarity), GO:0009886 (post-embryonic animal morphogenesis), GO:0016318 (ommatidial rotation), GO:0051128 (regulation of cellular component organization), GO:0051962 (positive regulation of nervous system development), GO:0048638 (regulation of developmental growth), GO:1901890 (positive regulation of cell junction assembly), GO:0050807 (regulation of synapse organization), GO:0048880 (sensory system development), GO:1901888 (regulation of cell junction assembly), GO:0035120 (post-embryonic appendage morphogenesis), GO:0007423 (sensory organ development), GO:0048707 (instar larval or pupal morphogenesis), GO:0090596 (sensory organ morphogenesis), GO:0035114 (imaginal disc-derived appendage morphogenesis), GO:0006796 (phosphate-containing compound metabolic process), GO:0002009 (morphogenesis of an epithelium), GO:0051960 (regulation of nervous system development), GO:1904398 (positive regulation of neuromuscular junction development), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0048737 (imaginal disc-derived appendage development), GO:0051965 (positive regulation of synapse assembly), GO:0048569 (post-embryonic animal organ development), GO:0007474 (imaginal disc-derived wing vein specification), GO:0045887 (positive regulation of synaptic assembly at neuromuscular junction), GO:0048563 (post-embryonic animal organ morphogenesis), GO:0007560 (imaginal disc morphogenesis), GO:0008582 (regulation of synaptic assembly at neuromuscular junction), GO:0007444 (imaginal disc development), GO:0060429 (epithelium development), GO:0001736 (establishment of planar polarity), GO:0048592 (eye morphogenesis), GO:0001654 (eye development), GO:0007472 (wing disc morphogenesis), GO:0006468 (protein phosphorylation), GO:0150063 (visual system development), GO:1904396 (regulation of neuromuscular junction development), GO:0016310 (phosphorylation), GO:0035220 (wing disc development), GO:0051963 (regulation of synapse assembly), GO:0007476 (imaginal disc-derived wing morphogenesis), GO:0001738 (morphogenesis of a polarized epithelium), GO:0048749 (compound eye development), GO:0001745 (compound eye morphogenesis), GO:0046777 (protein autophosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)