Protein: Ras and Rab interactor 2 (E7F662)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm
Sequence: MSVEMMMQSCLMDRSSSFFKLIDTFSTEISELKQEMVQPAREPETEILQGLEGEVSGLFLQSSACAGVPGVRDSGYDSLRRRMSMLDRLMQTHSVWLLLSLSDDEARHILQPQPAGSFVVRRCYKLQKKVISLRMDSDTLIVRDFPVKESQYTFSLEGSGISFADLFRLVAFCCISRDVLPFTLKLPEAIASAKTPTDLEEVAKLGKGFWDSELCNKNKSSVSGETACDGSKQRLKRSPAVPFTRTPSELECSQSNGALCFINPLFLQTHQSNPSPKKQEPSPGDEGGGSQHHHRALHRTGQQQGDSSVFCRKTPSKPHISVSRSESERSPPPRPPPPRFGSSRSAVLRKQKTMPETVCWIKTPQEKTSLLGRLGSSFISLSPSSSPPKKFSKPILVPSARNKNSSGLLDADGIRCHMALDDQTIEDAVSWSLAKLSSRNPTAMENGSPAHEHCSTGRERLSDISISTSSSDSLDFSHSFPLPMEASPSKTDRPTGDSSQEEEEDDGINLESDQEVPSPFKSKKQNSAGTFVLPRALRGQLRKMSDVLNSLMTPERRAIRKIVEQSRDKGTYFGCLVQDYVSFLQENRGCHTSGLELLQTLRQFMTQMKSYLLQSSELDPPIESLIPEDQIDQVMEKAMHKCVLKPLKPVIEAALRDFQLSSGTMQQLKENLLLAKAKQPQEMGVDGARPPDPVAIEKIRHKFNNMCKMYSPEKKVSLLLSVCKLIYTIMENNSGRMYGADDFLPMLTYVMAQCDMPELDTEIQYMMELLDPSLLHGEGGYYLTSAYGAMSLIKNFQEDQAARELSSETRNTLHQWHRRRTTQRTTPSVDDFQNYLRVALQDASSGCTAKTLQVQPYATTEDVCQICADKFKISDPENYALFLLTEETTQQLTLDTHPQKIKAELHSRPQPQIFYFVYRQIQNFPVLSEQLDDNTSAN
InterPro domains: - IPR045046: Vacuolar protein sorting-associated protein 9-like (family) [246-919]
- IPR003123: VPS9 domain (domain) [662-811]
- IPR037191: VPS9 domain superfamily (homologous_superfamily) [576-820]
- IPR036860: SH2 domain superfamily (homologous_superfamily) [91-214]
- IPR029071: Ubiquitin-like domain superfamily (homologous_superfamily) [832-899]
- IPR000159: Ras-associating domain (domain) [832-923]
- IPR000980: SH2 domain (domain) [96-188]
Interaction partners: - Ras-related protein Rab-35
- Ras-related protein Rab-35
- USP6 N-terminal-like protein
- Sorting nexin
- small monomeric GTPase
- High mobility group nucleosomal-binding domain 2
- E2 ubiquitin-conjugating enzyme
- RAB6-interacting golgin
- small monomeric GTPase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0048519 (negative regulation of biological process), GO:0032501 (multicellular organismal process), GO:0050793 (regulation of developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0050794 (regulation of cellular process), GO:0051093 (negative regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0000902 (cell morphogenesis), GO:0007162 (negative regulation of cell adhesion), GO:0045596 (negative regulation of cell differentiation), GO:0048731 (system development), GO:0030155 (regulation of cell adhesion), GO:0045595 (regulation of cell differentiation), GO:0010812 (negative regulation of cell-substrate adhesion), GO:0007399 (nervous system development), GO:0010810 (regulation of cell-substrate adhesion), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0022407 (regulation of cell-cell adhesion), GO:0022408 (negative regulation of cell-cell adhesion), GO:2000736 (regulation of stem cell differentiation), GO:2000737 (negative regulation of stem cell differentiation), GO:0001953 (negative regulation of cell-matrix adhesion), GO:1902036 (regulation of hematopoietic stem cell differentiation), GO:0060232 (delamination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)