Protein: RE26469p (Q8IGU8)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Sequence: LRFNRRWSQTCPKCQKYLPRFSENSALWNEIRMDPDNDIYAFYDIRGYKGKCRPGRPNSERILQPRMSLLGKPLNYNRGTRRDVRYRRLQSRLYNFLERPRGLHAIFYHVMVFLMVFTCLALSVFSTIKEYEEDAVYILFRMEILVVIWFTMEFGARLWSSGCRSRYQGCLGRLKFVKRPFCIIDIVTILASIVVLGMGTSGQVFATSALRGLRFFQILRMVRMDRRGGTWKLLGSVVYAHRQELITTMYIGFLGLIFASFLVYMWEKDVNDKFSNFAQALWWGVITLCTVGYGDMVPITWQGKLIASCCALLGISFFALPAGILGSGFALKVQQQQRQKHMIRRRQPAATLIQAVWRCYAADEHSVSVATWNIHRVALPSPPASRASSSFKHNTSFVARLPTIRRHKSQTIQTPGGGDGGGVSKPPGSSRASTRYTRTIRDINASVENLDEEDEPRCTQLTNRHKTAIRFIRKLKYFVARRKFKEALKPYDVKDVMEQYAAGHVDLLGRVKMLHLRLDQILGKQGSKAKDVYASKISLASRVVKVERQVADIEEKLDILIKAYMEDRDRFLALPLPAKPKIHSISPSHKPLHHAHNLAMIDVWKRTAALSVHPEQVTTTPLLNPSAPDSSELRSLTATQTPTTTTDAIATQTPMPPHVQHTATNTKSSVLNSYQLGSEKQQHNDVFMTELENRTKKRVTLSLHRSTSEPYSKQEQRIIIPDEGADSLDSSAKPTPPDSSIILIDEYEDFEEEDLNCEGEMDHFPTWEIDSDIGVEVDVDADADGDCDESTEDTALLQCATRTAIVITPISPVSSAHNLQQLNDQTTTLNKSNLLPPDSG
InterPro domains: - IPR003937: Potassium channel, voltage dependent, KCNQ (family) [58-410]
- IPR013821: Potassium channel, voltage dependent, KCNQ, C-terminal (domain) [445-566]
- IPR005821: Ion transport domain (domain) [105-336]
- IPR027359: Voltage-dependent channel domain superfamily (homologous_superfamily) [77-226]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0015267 (channel activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0005261 (monoatomic cation channel activity), GO:0022839 (monoatomic ion gated channel activity), GO:0022836 (gated channel activity), GO:0022843 (voltage-gated monoatomic cation channel activity), GO:0005244 (voltage-gated monoatomic ion channel activity), GO:0022832 (voltage-gated channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0051234 (establishment of localization), GO:0065008 (regulation of biological quality), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0051239 (regulation of multicellular organismal process), GO:0003008 (system process), GO:0003012 (muscle system process), GO:0009790 (embryo development), GO:0002027 (regulation of heart rate), GO:0003013 (circulatory system process), GO:0006810 (transport), GO:0044057 (regulation of system process), GO:0003015 (heart process), GO:0008015 (blood circulation), GO:0006811 (monoatomic ion transport), GO:1903522 (regulation of blood circulation), GO:0009792 (embryo development ending in birth or egg hatching), GO:0006936 (muscle contraction), GO:0006941 (striated muscle contraction), GO:0008016 (regulation of heart contraction), GO:0006812 (monoatomic cation transport), GO:0060047 (heart contraction), GO:0001700 (embryonic development via the syncytial blastoderm), GO:0060048 (cardiac muscle contraction), GO:0030001 (metal ion transport), GO:0006813 (potassium ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)