Protein: Alpha-galactosidase 1 (AtAGAL1) (EC 3.2.1.22) (Alpha-D-galactoside galactohydrolase 1) (Melibiase 1) (Q9FT97)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May regulate leaf (and possibly other organ) development by functioning in cell wall loosening and cell wall expansion.
Subcellular location: Secreted, cell wall {ECO:0000250|UniProtKB:Q8RX86}. Secreted, extracellular space, apoplast {ECO:0000250|UniProtKB:Q8RX86}.
Sequence: MSRRAMVIKMPILMILISSMVMTMVESSRSVNNGHDDSEILRRHLLTNGLGVTPPMGWNSWNHFSCNIDEKMIKETADALVTTGLSKLGYNYVNIDDCWAEISRDSKGSLVPKKSTFPSGIKAVADYVHSKGLKLGIYSDAGYFTCSKTMPGSLGYEEHDAKTFAEWGIDYLKYDNCNSDGSKPTVRYPVMTRALMKSGRPIFHSLCEWGDMHPALWGSPVGNSWRTTNDIKDTWLSMISIADMNEVYAEHARPGGWNDPDMLEVGNGGMTKDEYIVHFSIWAISKAPLLLGCDIRNMTKETMEIVANKEVIAINQDPHGVQAKKVRMEGDLEVWAGPLSGYRVALLLLNRGPSRTSITALWEDIEIPANSIVEARDLWEHQTLKQKFVGNLTATVDSHACKLYVLKPVA
InterPro domains: - IPR000111: Glycoside hydrolase family 27/36, conserved site (conserved_site) [89-105]
- IPR017853: Glycoside hydrolase superfamily (homologous_superfamily) [47-318]
- IPR002241: Glycoside hydrolase, family 27 (family) [14-408]
- IPR013785: Aldolase-type TIM barrel (homologous_superfamily) [46-319]
- IPR041233: Alpha galactosidase, C-terminal domain (domain) [329-406]
- IPR013780: Glycosyl hydrolase, all-beta (homologous_superfamily) [320-409]
Interaction partners: - Probable galactinol--sucrose galactosyltransferase 1
- Probable galactinol--sucrose galactosyltransferase 5
- Probable galactinol--sucrose galactosyltransferase 2
- Probable galactinol--sucrose galactosyltransferase 6
- alpha-D-xyloside xylohydrolase
- Probable galactinol--sucrose galactosyltransferase 4
- beta-galactosidase
- Aldose 1-epimerase
- Beta-hexosaminidase 3
- Beta-hexosaminidase 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds), GO:0015925 (galactosidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:1901575 (organic substance catabolic process), GO:0043170 (macromolecule metabolic process), GO:0005975 (carbohydrate metabolic process), GO:0016052 (carbohydrate catabolic process), GO:0009057 (macromolecule catabolic process), GO:0005976 (polysaccharide metabolic process), GO:0000272 (polysaccharide catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0030312 (external encapsulating structure), GO:0005576 (extracellular region), GO:0048046 (apoplast), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005618 (cell wall), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0009505 (plant-type cell wall), GO:0097708 (intracellular vesicle)