Protein: Uncharacterized CDP-alcohol phosphatidyltransferase class-I family protein C22A12.10 (O13901)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Subcellular location: Membrane; Multi-pass membrane protein
Sequence: MQLNRKQLKNLHNYKYSAIDNSLLSKYILKPYWWNQLLKVIPMSMAPNLITLIGLGFVVINILTMLVYKYHYEMDAFPSWVYASWAIGLFLYQSFDAIDGSQARRTGTSSPLGQLFDHGVDAINTSFEVLLTIELLQLDMFSSILTQFASLLYFYISTWEEYHTGTLYLSYFSGPVEGIVMVIGLFALTAIKGDSFWLKLHPTPESWGFVRSFLPYYTYGSCLYNFMAFALLLNVLQSLRNALQAVQKNNGSVIKALSGILPYFLQWMAVFSLYAKYPAFFEHHFLTIFCLNAFIFAYSVGVVIVSHITESPFPYWNVLILPFLVDAVDAYTFGVLKNVQTEYFFCYVGICIGVYGNFVAHVIAMITEEYGIKCLTIPSKPESKKN
InterPro domains: - IPR014472: Choline/ethanolamine phosphotransferase (family) [2-385]
- IPR048254: CDP-alcohol phosphatidyltransferase, conserved site (conserved_site) [99-121]
- IPR000462: CDP-alcohol phosphatidyltransferase (family) [46-190]
- IPR043130: CDP-alcohol phosphatidyltransferase, transmembrane domain (homologous_superfamily) [21-200]
Interaction partners: - Probable ethanolamine-phosphate cytidylyltransferase
- Phosphatidylserine decarboxylase proenzyme 3
- Phosphatidylserine decarboxylase proenzyme 1, mitochondrial
- Phosphatidylserine decarboxylase proenzyme 2, mitochondrial
- Phosphatidyl-N-methylethanolamine N-methyltransferase
- Phospholipase D1
- Nuclear elongation and deformation protein 1
- CDP-diacylglycerol--inositol 3-phosphatidyltransferase
- Lysophospholipid acyltransferase
- Phosphatidylethanolamine N-methyltransferase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016780 (phosphotransferase activity, for other substituted phosphate groups), GO:0017169 (CDP-alcohol phosphatidyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006629 (lipid metabolic process), GO:0019637 (organophosphate metabolic process), GO:0006793 (phosphorus metabolic process), GO:0046470 (phosphatidylcholine metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0046486 (glycerolipid metabolic process), GO:0006644 (phospholipid metabolic process), GO:0008610 (lipid biosynthetic process), GO:0045017 (glycerolipid biosynthetic process), GO:0090407 (organophosphate biosynthetic process), GO:0006650 (glycerophospholipid metabolic process), GO:0046474 (glycerophospholipid biosynthetic process), GO:0008654 (phospholipid biosynthetic process), GO:0006656 (phosphatidylcholine biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0031090 (organelle membrane), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098827 (endoplasmic reticulum subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0005789 (endoplasmic reticulum membrane)