Protein: Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb (A0A2R8Q5T8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted
Sequence: MLLDSLWPVQVLLVLSVLTLVLGNEPQNAPRVFLSFKDLRSTGTAHYFSFLLNTSDYRILRMDEDHDRMYVGSKDYILSLDLHDINREPLIIHWPVSPQRKTECVLSGKDTNGECGNFIRLIEPWNRTHLYICGTGAYNPVCTYVNRGRKPMTAMHLQMPQTRGRASRAAEPETVFDETGLQEYVFHLEPGKEDSGKGKCPYDPKLNSVSALINGELYAGVYIDFMGTDSAIFRTLGKNAVMRTDQYNSRWLNDPSFVHVHLIPDSGEKNDDKLYFFFREKSSEMGQSPKSQSRIGRICLNDDGGHCCLVNKWSTFLKARLICSVPGADGIETHFDELRDVYIQPTQDTKNPVIYGVFSVSGSVFKGSAVCVYSMADIRMVFNGPFAHKEGPNYQWVAYTGKIPYPRPGTCPGGTFTPNMKSTKDYPDEVINFMRNHPTMYNSVYPVHKRPLVVRTNVDYEFTTITVDQVTAADGNYEVLFLGTDRGTVQKVIVLPSDDLQTEELVLEEVEVFKVPTSITTMKISSKRQQLYVASAVGVTHMALHRCDVYGEACADCCLARDPYCAWDGKSCSRYSASQKRLPFRRSRRQDVKYGNPIRQCRGYNSNINKNTLETVQYGVEGSSTFLECQARSPHAAIKWHLHRDNSDRRREVRSDGRVLKTDQGLLLRSLQSSDSGIYICTATEKNFKHTLVKLQLLVLTNQAVNNILVDTGRPVVSPLQSSAWTPSAGQYKDLLTILSQPEMGLINQYCQDYWQYGDPLTGVIKAKDLKELKEQKKPRNRRHHGDEEET
InterPro domains: - IPR027231: Semaphorin (family) [12-774]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [616-699]
- IPR003599: Immunoglobulin domain subtype (domain) [614-700]
- IPR003598: Immunoglobulin subtype 2 (domain) [620-688]
- IPR007110: Immunoglobulin-like domain (domain) [621-693]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [619-699]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [26-548]
- IPR036352: Sema domain superfamily (homologous_superfamily) [29-550]
- IPR001627: Sema domain (domain) [31-544]
- IPR016201: PSI domain (domain) [546-602]
Interaction partners: - Neuropilin-1a
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0042221 (response to chemical), GO:0042330 (taxis), GO:0071840 (cellular component organization or biogenesis), GO:0032989 (cellular component morphogenesis), GO:0000902 (cell morphogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0016043 (cellular component organization), GO:0006935 (chemotaxis), GO:0022008 (neurogenesis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0097485 (neuron projection guidance), GO:0032990 (cell part morphogenesis), GO:0048858 (cell projection morphogenesis), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0007411 (axon guidance), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0048812 (neuron projection morphogenesis), GO:0061564 (axon development), GO:0007409 (axonogenesis), GO:0008045 (motor neuron axon guidance)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005576 (extracellular region), GO:0005615 (extracellular space), GO:0031012 (extracellular matrix), GO:0062023 (collagen-containing extracellular matrix)