wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Octaprenyl diphosphate synthase (EC 2.5.1.90) (All-trans-octaprenyl-diphosphate synthase) (Octaprenyl pyrophosphate synthase) (OPP synthase) (P0AD57)
Organism: Escherichia coli (strain K12)
Function: Supplies octaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone and menaquinone.
Sequence: MNLEKINELTAQDMAGVNAAILEQLNSDVQLINQLGYYIVSGGGKRIRPMIAVLAARAVGYEGNAHVTIAALIEFIHTATLLHDDVVDESDMRRGKATANAAFGNAASVLVGDFIYTRAFQMMTSLGSLKVLEVMSEAVNVIAEGEVLQLMNVNDPDITEENYMRVIYSKTARLFEAAAQCSGILAGCTPEEEKGLQDYGRYLGTAFQLIDDLLDYNADGEQLGKNVGDDLNEGKPTLPLLHAMHHGTPEQAQMIRTAIEQGNGRHLLEPVLEAMNACGSLEWTRQRAEEEADKAIAALQVLPDTPWREALIGLAHIAVQRDR
InterPro domains: - IPR008949: Isoprenoid synthase domain superfamily (homologous_superfamily) [1-323]
- IPR000092: Polyprenyl synthetase-like (family) [27-321]
- IPR033749: Polyprenyl synthetase, conserved site (conserved_site) [81-215]
Interaction partners: - Ditrans,polycis-undecaprenyl-diphosphate synthase
- 4-hydroxybenzoate octaprenyltransferase
- Farnesyl diphosphate synthase
- 1,4-dihydroxy-2-naphthoate octaprenyltransferase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups), GO:0043169 (cation binding), GO:0004659 (prenyltransferase activity), GO:0046872 (metal ion binding), GO:0000287 (magnesium ion binding), GO:0046914 (transition metal ion binding), GO:0005506 (iron ion binding), GO:0030145 (manganese ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0042180 (cellular ketone metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901576 (organic substance biosynthetic process), GO:0044283 (small molecule biosynthetic process), GO:1901661 (quinone metabolic process), GO:0042181 (ketone biosynthetic process), GO:0009233 (menaquinone metabolic process), GO:1901663 (quinone biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005829 (cytosol), GO:1902494 (catalytic complex), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:1990234 (transferase complex)
Protein: Azurocidin 1 (A0A087WXP0)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNVSAPCGGRRGPERY
InterPro domains: - IPR043504: Peptidase S1, PA clan, chymotrypsin-like fold (homologous_superfamily) [1-136]
- IPR009003: Peptidase S1, PA clan (homologous_superfamily) [1-137]
- IPR001254: Serine proteases, trypsin domain (domain) [1-150]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0017171 (serine hydrolase activity), GO:0008233 (peptidase activity), GO:0008236 (serine-type peptidase activity), GO:0004175 (endopeptidase activity), GO:0004252 (serine-type endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050794 (regulation of cellular process), GO:0030155 (regulation of cell adhesion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0099080 (supramolecular complex), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0035770 (ribonucleoprotein granule), GO:0036464 (cytoplasmic ribonucleoprotein granule), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0010494 (cytoplasmic stress granule)
Protein: Ubiquitin carboxyl-terminal hydrolase-related protein (F4IGQ3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MKRTTFLEDAERVKLYNDARALFANGDHIKALEIIEDIILVHKEDEKSWILHSEQGEMFNDLAGKAENPYVDFTYMLGSVGCYSKDVLLSRPWAHGLHYLAQESGSVMYYKKCVNVAKQGLSVTFPDASESFAQLLLENLKNDMKENLETLIKDAESNIADSKTVELKGLLQQDFEPEVLESKKRPELVKNEFKGLRSFWLGLDVNVKRDFMKVSIAKLIGFVKGVHHRPGRDALKQILDSAKEDRKWTFWMCRTKCSKKFSSAEECKNHLEKEHAADYKPFSEMDMAKRIGKDWTRKISLGSWEPVDIAAAVEMIKNRLPEVKAFSYKNGWSKEWPLAEDEERSKLLKEIKFFLVMFCDLKILPCSIRDWMKRYSVTHLKNLNVSEQSLVDSHLVDTPQSICFLECHKLSYILNLLKRIKCERDDGTNLVRRAVDSILDSTRSKEKIDFDPQFSFLLLDRRLLKSNNGPFVDEGEINVFDPNVHYAKAHAQGDDIVSWLTDYNSVEKTFPRPIREHNLDIWVAVLRAVQFTCRTFGTKYAKKVQLFDYLAAIVAAEKLCKSEYERRRKLKEDQWNSYASLLCDKCEECFSRKNFLKRKLFLSVVRDILEEASDLTFDLPDIEGCMNLIREHKSLNDDIVLKSLICLNSVVIFKILLIDSKILLVDNSRISLLNNLTRLSLFDNRTYILQLLKPFLLNEIVNMESKAKSDAAVADLLLEEEKKNPKPSPIQSKKKKNTSKKRNSTSMSSPLSKPGEHLEPETTSPTVEEDSMELGDTVNQEEVMKNMLGEDSQSEHLESALSEASARYNSALDMTLKALLNIKILKEDLMHNMQPLQHHLEDQVPSVLQNFFTAFVSEEIKTEGVYSYLLSDLLALLEEVLSMSSGAAEVLVAILEFWHCWKNAERESLVTRLFTLEEKERMSCRKCRKKPNYPEQSSYGIVMAADSIRDLKCALGNIEFVDILKVIRMDYTMLCDIKNGGCGIANFIHHIISKCPPIFTIVLEWEKSETEKEISETTKAFEWEIDISRLYAGLEPKTNYRLASMVGCDEKQEHICIAYEKNRWVNLRRDALAGEDVGNWKSVVRFCGERKVRPEILFYEVVRSMA
InterPro domains: - IPR052398: Ubiquitin carboxyl-terminal hydrolase 53/54 (family) [19-1100]
- IPR013087: Zinc finger C2H2-type (domain) [251-280]
- IPR006866: Domain of unknown function DUF627, N-terminal (domain) [18-124]
- IPR001394: Peptidase C19, ubiquitin carboxyl-terminal hydrolase (domain) [806-1099]
- IPR006865: Domain of unknown function DUF629 (domain) [196-654]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008234 (cysteine-type peptidase activity), GO:0019783 (ubiquitin-like protein peptidase activity), GO:0101005 (deubiquitinase activity), GO:0004843 (cysteine-type deubiquitinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0003006 (developmental process involved in reproduction), GO:0009791 (post-embryonic development), GO:0048316 (seed development), GO:0009790 (embryo development), GO:0048608 (reproductive structure development), GO:0009793 (embryo development ending in seed dormancy), GO:0048731 (system development), GO:0061458 (reproductive system development), GO:0010154 (fruit development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Thioredoxin Y1, chloroplastic (AtTrxy1) (Q6NPF9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Thiol-disulfide oxidoreductase that poorly activates chloroplastic malate dehydrogenase (NADP-MDH) and fructose-1,6-bisphosphatase. Provides reducing equivalents for peroxiredoxin Q.
Subcellular location: Plastid, chloroplast stroma {ECO:0000269|PubMed:15531707, ECO:0000269|PubMed:19259774}.
Sequence: MASISLSSSTVPSLNSKESSGVSAFASRSISAVKFQFPVRRVRTGDLKFPSLSSTTRCTPRRIEAKKQTFDSFEDLLVNSDKPVLVDYYATWCGPCQFMVPILNEVSETLKDKIQVVKIDTEKYPSIANKYKIEALPTFILFKDGEPCDRFEGALTAKQLIQRIEDSLKVKP
InterPro domains: - IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [69-169]
- IPR017937: Thioredoxin, conserved site (conserved_site) [85-103]
- IPR013766: Thioredoxin domain (domain) [5-169]
- IPR005746: Thioredoxin (family) [70-166]
Interaction partners: - Ferredoxin-thioredoxin reductase catalytic chain, chloroplastic
- Zinc finger BED domain-containing protein DAYSLEEPER
- Ubinuclein-2
- Expressed protein
- Ribonuclease H
- Terpenoid synthase 1
- Capsid-like protein
- ATP-dependent DNA helicase DDM1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0016491 (oxidoreductase activity), GO:0016667 (oxidoreductase activity, acting on a sulfur group of donors), GO:0008047 (enzyme activator activity), GO:0016671 (oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0065007 (biological regulation), GO:0009628 (response to abiotic stimulus), GO:0065009 (regulation of molecular function), GO:0050790 (regulation of catalytic activity), GO:0009314 (response to radiation), GO:0044093 (positive regulation of molecular function), GO:0043085 (positive regulation of catalytic activity), GO:0009416 (response to light stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009532 (plastid stroma), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009570 (chloroplast stroma), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Lectin-like transmembrane protein (Q6DUV0)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
Sequence: MSEQEVTYSTVRFHKSSGLQNQVRPEDNQGSREAGHKECSIPWHLIVIAFGILCVLLLVIVAVLVTNILQYKQEKHELQETLNCHHNCSTMQSDINAKEEMLRNMPLECSTGDDLLKSLNREQKRWYSETKSVLNSSKHPGGSLEIHWFCYGIKCYYFIMNKKGWHKCKQICEHYSLSLLKIDAEDELKFLQLQVTPDSYWIGFSFDKKSEKWTWIENGTSKYALNMSTYNVKSGECVFLSKTRLENNKCEHVYPCICEKRLDKFPDSLPNNS
InterPro domains: - IPR013600: Ly49-like, N-terminal (domain) [40-158]
- IPR016186: C-type lectin-like/link domain superfamily (homologous_superfamily) [131-267]
- IPR052013: Mouse Killer cell lectin-like receptors (family) [1-267]
- IPR016187: C-type lectin fold (homologous_superfamily) [130-263]
- IPR001304: C-type lectin-like (domain) [144-260]
- IPR033992: Natural killer cell receptor-like, C-type lectin-like domain (domain) [145-260]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0042287 (MHC protein binding), GO:0042288 (MHC class I protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007166 (cell surface receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: UPF0598 protein C8orf82 homolog (Q8VE95)
Organism: Mus musculus (Mouse)
Function: Not known
Sequence: MWPPSGAVRNLALVLARSQRARTCSGVERVSYTQGQSPEPRTREYFYYVDHQGQLFLDDSKMKNFITCFKDLQFLVTFFSRLRPNHSGRYEASFPFLSLCGRERNFLRCEDRPVVFTHLLASDSESPRLSYCGGGEALAIPFEPARLLPLAANGRLYHPAPERAGGVGLVRSALAFELSACFEYGPSSPTVPSHVHWQGRRIALTMDLAPLLPAAPPP
InterPro domains: - IPR028108: Protein of unknown function DUF4505 (family) [13-211]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0071310 (cellular response to organic substance), GO:0034097 (response to cytokine), GO:1990823 (response to leukemia inhibitory factor), GO:0071345 (cellular response to cytokine stimulus), GO:1990830 (cellular response to leukemia inhibitory factor)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Receptor expression-enhancing protein 5 (Q6PBX9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Plays an essential role in heart function and development by regulating the organization and function of the sarcoplasmic reticulum in cardiomyocytes.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q60870}; Multi-pass membrane protein {ECO:0000255}. Sarcoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q60870}; Multi-pass membrane protein {ECO:0000255}.
Sequence: MAAALKQRFDNALHEKNMVTDLLAKIEAKTGVNRSYIAYAVIAFIAIYLVIGYGASLLCNLIGFVYPAYISIKAIESPAKDDDTKWLTYWVVYGVFSVVEFFADIFLSWFPFYFLAKCAFLVWCMAPTPSNGSIMLYTRIIRPFFLKNEAKIDNVMKDLTDKAAGAADKIKDEAKKATANIMFEEKKHY
InterPro domains: - IPR004345: TB2/DP1/HVA22 (family) [53-173]
Interaction partners: - Reticulon.
- Reticulon
- Reticulon
- Reticulon
- Reticulon
- Reticulon
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0010842 (retina layer formation), GO:0060042 (retina morphogenesis in camera-type eye), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0003407 (neural retina development), GO:0009790 (embryo development), GO:0060041 (retina development in camera-type eye), GO:0060059 (embryonic retina morphogenesis in camera-type eye), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0090596 (sensory organ morphogenesis), GO:0048592 (eye morphogenesis), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0043010 (camera-type eye development), GO:0048593 (camera-type eye morphogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098827 (endoplasmic reticulum subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0071782 (endoplasmic reticulum tubular network)
Protein: Uncharacterized protein At2g14060 (Q9ZPT3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MKGGTGDHSYATNSHYQRSVFYEIQPLVIENVREMLLKNGFPGCIKVADLGCSTGQNTVLAMSAIAYTIMESYQQMSKNPPEIDCYLNDLPENDFNTTFKLFHSFQEKLKPEVKGKWFVSGVPGSFYSRLFPRKSLHFVHSAFSIHWLSRIPDGLESNTKSIHIKYPYPSNVYKSYLNQFKIDFSLFLKMRSEEVVHNGHMVLTFVGRKVSDTLSKDCFQVWSLLSDCLLDLASEGFVNDSMVKSFNMPFYNPNEEEVREFILKEGSFEITKIEKFDHVVPYKIDREEEDEEQSLQLEAGIKHASWARCITEPLLVAHFGDAIIEPVFNKYAHYMAKYLSVSNHRRNMTLVIVVSLTRK
InterPro domains: - IPR005299: SAM dependent carboxyl methyltransferase (family) [2-358]
- IPR029063: S-adenosyl-L-methionine-dependent methyltransferase superfamily (homologous_superfamily) [1-359]
- IPR042086: Methyltransferase, alpha-helical capping domain (homologous_superfamily) [1-342]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0008168 (methyltransferase activity), GO:0008171 (O-methyltransferase activity), GO:0008757 (S-adenosylmethionine-dependent methyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0006082 (organic acid metabolic process), GO:0006631 (fatty acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0016053 (organic acid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0006633 (fatty acid biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process), GO:0072330 (monocarboxylic acid biosynthetic process), GO:0032787 (monocarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Ras-related protein Rab-7a (Q23146)
Organism: Caenorhabditis elegans
Function: Not known
Sequence: MSGTRKKALLKVIILGDSGVGKTSLMNQYVNRRFSNQYKATIGADFLTRDVNIDDRTVTLQIWDTAGQERFQSLGVAFYRGADCCVLAFDVTNAASFKSLDSWRDEFLIQASPRDPDHFPFVLLGNKVDLESQRAVSSKRAQSWCQTKGNIPYYEVSAKEALNVEAAFLAIARDALARESQETNDFPEFPDQIRLNPNQQNQQNSGCNC
InterPro domains: - IPR001806: Small GTPase (family) [5-209]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [3-199]
- IPR005225: Small GTP-binding domain (domain) [10-168]
Interaction partners: - Vacuolar protein sorting-associated protein 18 homolog
- Vacuolar protein sorting-associated protein 16 homolog
- Vacuolar protein sorting-associated protein 39 homolog
- Vacuolar protein sorting-associated protein 11 homolog
- Rab GDP dissociation inhibitor
- Vacuolar protein sorting-associated protein 41 homolog
- Vacuolar fusion protein CCZ1 homolog
- TBC1 domain family member 15
- Vacuolar fusion protein MON1 homolog
- PH domain-containing protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0097367 (carbohydrate derivative binding), GO:0005515 (protein binding), GO:1901265 (nucleoside phosphate binding), GO:0043168 (anion binding), GO:0000166 (nucleotide binding), GO:0032553 (ribonucleotide binding), GO:0035639 (purine ribonucleoside triphosphate binding), GO:0032555 (purine ribonucleotide binding), GO:0017076 (purine nucleotide binding), GO:0005525 (GTP binding), GO:0019001 (guanyl nucleotide binding), GO:0032561 (guanyl ribonucleotide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0046907 (intracellular transport), GO:0051649 (establishment of localization in cell), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport), GO:0016197 (endosomal transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0030659 (cytoplasmic vesicle membrane), GO:0012506 (vesicle membrane), GO:0097708 (intracellular vesicle)
Protein: Septin-2 (P54359)
Organism: Drosophila melanogaster (Fruit fly)
Function: Involved in cytokinesis.
Subcellular location: Cytoplasm. Cytoplasm, cytoskeleton, spindle {ECO:0000250}.
Sequence: MSVEVDFVDKKEVHLRTLKQSGHVGFDSLPDQLVNKSVQNGFVFNVMCIGETGLGKSTLMDTLFNTSFESTPSPHTLPSVKLKAHTYELQESNVRLKLTICDTVGYGDQINKDDSFKAVVDYIDAQFENYLQEELKIKRSLVTCHDSRIHICLYFICPTGHGLKSLDLVCMKKLDSKVNIIPVIAKADTISKVELQRFKAKIIQELNANGVHIYQFPTDDETVAETNTSMNSHIPFAVVGSTEFIKVGNKLIRARQYPWGTVQVENETHCDFVKLREMLIRTNMEDMREKTHTRHYELYRQKRLEQMGFSDVDSDNKPISFQQTFEAKRSNHLAELQSKEEEVRQMFVQRVKEKEAELKESEKDLHAKFEKLKRDHAEEKRKLEESRKALEEDYLDFQRRKQQLATAHHTLTLGKSKKK
InterPro domains: - IPR016491: Septin (family) [4-419]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [18-308]
- IPR030379: Septin-type guanine nucleotide-binding (G) domain (domain) [40-307]
Interaction partners: - Septin-1
- Protein peanut
- Septin
- Septin
- Anillin
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0050794 (regulation of cellular process), GO:0009653 (anatomical structure morphogenesis), GO:0009791 (post-embryonic development), GO:0051726 (regulation of cell cycle), GO:0048736 (appendage development), GO:0002165 (instar larval or pupal development), GO:0007552 (metamorphosis), GO:0035107 (appendage morphogenesis), GO:0009887 (animal organ morphogenesis), GO:0009886 (post-embryonic animal morphogenesis), GO:0048513 (animal organ development), GO:0035114 (imaginal disc-derived appendage morphogenesis), GO:0048563 (post-embryonic animal organ morphogenesis), GO:0007560 (imaginal disc morphogenesis), GO:0007444 (imaginal disc development), GO:0048737 (imaginal disc-derived appendage development), GO:0035120 (post-embryonic appendage morphogenesis), GO:0048707 (instar larval or pupal morphogenesis), GO:0048569 (post-embryonic animal organ development), GO:0007476 (imaginal disc-derived wing morphogenesis), GO:0035220 (wing disc development), GO:0007472 (wing disc morphogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0070938 (contractile ring), GO:0016020 (membrane), GO:0031105 (septin complex), GO:0032153 (cell division site), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0098590 (plasma membrane region), GO:0043229 (intracellular organelle), GO:0032154 (cleavage furrow), GO:0005938 (cell cortex), GO:0005886 (plasma membrane), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0032156 (septin cytoskeleton)