Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (A0A0G2K7W4)
Organism: Rattus norvegicus (Rat)
Function: Not known
Sequence: MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEDEKRRVEREQEYIRRQLEEEQRHLEILQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHAQQPPPPQQQDRSKPSYHAPEPKPHYDPADRAREVEDRFRKTNHSSPEAQAKQTGRGLEPPVPSRSESFSNGNSESVHPALQRPAEPQVQWSHLASLKNNVSPVSRSHSFSDPSPKFAHHHLRSQDPCPPSRSEGLSQSSDSKSEVPEPTQKAWSRSDSDEVPPRVPVRTTSRSPVLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAAKKPEDKKEVFRPLKPADLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEEEDVEQEGADDSTSGPEDTRAASSLNLSNGETESVKTMIVHDDVESEPAMTPSKEGTLIVRQSTVDQKRASHHESNGFAGRIHLLPDLLQQSHSSSTSSTSSSPSSSQPTPTMSPQTPQDKLTANETQSASSTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSCDGLRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLISRRRFQQMDVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQCTIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [24-290]
- IPR001180: Citron homology (CNH) domain (domain) [1061-1359]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [149-161]
- IPR051700: STE20 Ser/Thr Protein Kinase (family) [5-1378]
- IPR017441: Protein kinase, ATP binding site (binding_site) [31-54]
- IPR000719: Protein kinase domain (domain) [25-289]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0065008 (regulation of biological quality), GO:0050793 (regulation of developmental process), GO:0023057 (negative regulation of signaling), GO:0051051 (negative regulation of transport), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0051093 (negative regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0046888 (negative regulation of hormone secretion), GO:0010648 (negative regulation of cell communication), GO:1903530 (regulation of secretion by cell), GO:0070570 (regulation of neuron projection regeneration), GO:0051049 (regulation of transport), GO:0051129 (negative regulation of cellular component organization), GO:0010646 (regulation of cell communication), GO:1903828 (negative regulation of protein localization), GO:0080134 (regulation of response to stress), GO:0060341 (regulation of cellular localization), GO:0051224 (negative regulation of protein transport), GO:0080135 (regulation of cellular response to stress), GO:0010817 (regulation of hormone levels), GO:0051128 (regulation of cellular component organization), GO:0070571 (negative regulation of neuron projection regeneration), GO:0051048 (negative regulation of secretion), GO:1903531 (negative regulation of secretion by cell), GO:0046883 (regulation of hormone secretion), GO:0061179 (negative regulation of insulin secretion involved in cellular response to glucose stimulus), GO:0051223 (regulation of protein transport), GO:0090276 (regulation of peptide hormone secretion), GO:0031344 (regulation of cell projection organization), GO:0090087 (regulation of peptide transport), GO:0070201 (regulation of establishment of protein localization), GO:0002792 (negative regulation of peptide secretion), GO:0050709 (negative regulation of protein secretion), GO:0051046 (regulation of secretion), GO:0032880 (regulation of protein localization), GO:0031345 (negative regulation of cell projection organization), GO:0050708 (regulation of protein secretion), GO:1904950 (negative regulation of establishment of protein localization), GO:0090278 (negative regulation of peptide hormone secretion), GO:0046676 (negative regulation of insulin secretion), GO:0002791 (regulation of peptide secretion), GO:0061178 (regulation of insulin secretion involved in cellular response to glucose stimulus), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0010977 (negative regulation of neuron projection development), GO:0050796 (regulation of insulin secretion), GO:0010975 (regulation of neuron projection development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098794 (postsynapse), GO:0098793 (presynapse), GO:0030054 (cell junction), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0099572 (postsynaptic specialization), GO:0043228 (non-membrane-bounded organelle), GO:0098984 (neuron to neuron synapse), GO:0099091 (postsynaptic specialization, intracellular component), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0014069 (postsynaptic density), GO:0098978 (glutamatergic synapse), GO:0032279 (asymmetric synapse), GO:0099092 (postsynaptic density, intracellular component)