Protein: Calcium-binding mitochondrial carrier protein Aralar1-like Protein (D6W9D8)
Organism: Tribolium castaneum (Red flour beetle)
Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein
Sequence: MDTFLAKAYCQEGGGYLRRANPQHLHDIFNKYASQEKNGERFMTPEDFIIKYLGLFEPENFNAHSVRLLAGIVDTSKDGLISYSEFQAFEGLLCFPDALYKTAFQLFDTNGNGMVSFQEFVEVMKKTELHERIPFNMDSPFIQLYFGRDKKRLVPYSEFSQFLHDFHEEYAIEGFRRADKTGSGFISVLDFQFIMTNIKSHLLTKQVQSHLIETAQGATSGRRVSFPYFIAFNSLLNNMELAKRIYLNVTNGHRTQEVTKEEFMHSAQAMSQMTPLEVDILFQLCDVLHQTGRIVYNDLNAIAPEQYYKQITNRLAEIHAVSSPEDRGVFIQVLESMYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRTGSFIGELMYRNSIDCFKKVIRHEGVFGLYRGLVPQLMGVAPEKAIKLTVNDFVRDKFYDKNGNISGIGEVISGAAAGASQVIFTNPLEIVKIRLQVAGEIAGGSKVRAWHVVKELGLFGLYKGAKACLLRDIPFSAIYFPTYAHTKAKFADETGYNHPLSLLAAGAIAGVPAAGLVTPADVIKTRLQVVARAGQTTYNGVFDAARKIYVEEGFRAFWKGAIARVCRSSPQFGVTLVTYEVLQRMLYIDFGGTRPAGSELKVTALGGDAPKLQKPDHVGGYSVSIPVFSGIETKFGLCLPKLGLLSERK
InterPro domains: - IPR011992: EF-hand domain pair (homologous_superfamily) [23-299]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [108-120]
- IPR002067: Mitochondrial carrier protein (family) [339-556]
- IPR023395: Mitochondrial carrier protein domain superfamily (homologous_superfamily) [331-616]
- IPR018108: Mitochondrial carrier protein, transmembrane region (repeat) [334-615]
- IPR002048: EF-hand domain (domain) [65-201]
- IPR051028: Mitochondrial Solute Carrier (family) [268-666]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0005342 (organic acid transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity), GO:0042887 (amide transmembrane transporter activity), GO:0046943 (carboxylic acid transmembrane transporter activity), GO:0005313 (L-glutamate transmembrane transporter activity), GO:0015171 (amino acid transmembrane transporter activity), GO:0015179 (L-amino acid transmembrane transporter activity), GO:0015172 (acidic amino acid transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0044237 (cellular metabolic process), GO:0055085 (transmembrane transport), GO:1990542 (mitochondrial transmembrane transport), GO:0006091 (generation of precursor metabolites and energy), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0015980 (energy derivation by oxidation of organic compounds), GO:0071705 (nitrogen compound transport), GO:0015931 (nucleobase-containing compound transport), GO:0045333 (cellular respiration), GO:0015748 (organophosphate ester transport), GO:0022904 (respiratory electron transport chain), GO:0019646 (aerobic electron transport chain), GO:0009060 (aerobic respiration), GO:0015865 (purine nucleotide transport), GO:0006119 (oxidative phosphorylation), GO:0051503 (adenine nucleotide transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)