Protein: Threonylcarbamoyl-AMP synthase (EC 2.7.7.87) (L-threonylcarbamoyladenylate synthase) (Q8I610)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Sequence: MALIIKGNEIFENEDLRKKLKEHIEGDKLIGIPTETVYGLGGNSLSQRSLQNIFRMKNRPVSDPIISHVYNIYQAYDQLYHINIYEKYIIYILSKYFWPGPLSIIAKAKKEAPLILTAYTQFCAVRIPDNKITREIIKICNTPIAAPSANKFQHISPTNSLHVYDEFKNEDLLIFDDGQCDVGIESTVLKITKYRINHEDKNTDEVLKEKDVNVMKDIKKINNINVNNSEGNNPVEIVNDEEYECECNEELAFLRAATNSKESESNMEVYEKLKNMFDLIERMNSINNDDDNNNNDDNNNNDNNNNNNIIVDKILKYKSLYNYSIKIYRRGKYTKGDIENVLKKYDLLKDINVEMYEKIKFENLDIFKNEYPKSGIKDYRCDNINKEDDIYKTFNNEIEKNEVCPGLLLTHYSPFVSTYLLDIISCKTIEKENKGELLETNNNVCKKINLNKCVLLDIGSSLLKYDKNFLKYINICYDSLEVNERIKYITKQFFLFLRQAERLAIENKADNILISIVNIKSCDENYLSIFDRIYRAASGKMINLFIEHKDIIAYIK
InterPro domains: - IPR005145: Threonylcarbamoyl-AMP synthase, C-terminal domain (domain) [398-538]
- IPR050156: Threonylcarbamoyl-AMP synthase, SUA5 (family) [18-342]
- IPR038385: Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily (homologous_superfamily) [393-554]
- IPR006070: Threonylcarbamoyl-AMP synthase-like domain (domain) [14-212]
- IPR017945: DHBP synthase RibB-like alpha/beta domain superfamily (homologous_superfamily) [13-194]
Interaction partners: - riboflavin kinase
- N
- tRNA N6-adenosine threonylcarbamoyltransferase
- tRNA N6-adenosine threonylcarbamoyltransferase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0016740 (transferase activity), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0097367 (carbohydrate derivative binding), GO:1901265 (nucleoside phosphate binding), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0043168 (anion binding), GO:0000166 (nucleotide binding), GO:0032553 (ribonucleotide binding), GO:0035639 (purine ribonucleoside triphosphate binding), GO:0016779 (nucleotidyltransferase activity), GO:0032555 (purine ribonucleotide binding), GO:0017076 (purine nucleotide binding), GO:0005524 (ATP binding), GO:0032559 (adenyl ribonucleotide binding), GO:0030554 (adenyl nucleotide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0043412 (macromolecule modification), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0009451 (RNA modification), GO:0006400 (tRNA modification), GO:0034470 (ncRNA processing), GO:0070525 (tRNA threonylcarbamoyladenosine metabolic process), GO:0034660 (ncRNA metabolic process), GO:0002949 (tRNA threonylcarbamoyladenosine modification), GO:0006399 (tRNA metabolic process), GO:0008033 (tRNA processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0020011 (apicoplast), GO:0043231 (intracellular membrane-bounded organelle)