Protein: Echinoid, isoform C (M9PCI6)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Sequence: MRRKTTTKGTAIVNSRSARRAATTICNFFLIALVALSSTTLADESIDTRENADLTLKCRFNDKYEANDFSFFWTRWTANPAQFDNVAIGEVQLSSGYRLDFQPERGIYDLQIKNVSYNRDNGRFECRIKAKGTGADVHQEFHNLTVLTPPHPPVISPGNIAVATEDKPMELTCSSIGGSPDPTITWYREGSNTPLPATVLKGGTKDQPTNATLSIIPRREDDGAKYKCVVRNRAMNEGKRLEATATLNVNYYPRVEVGPENPLRVERDRTAKLECNVDAKPKVPNVRWNRNGRFISSSLVHTIHRVSVQDAGKYTCIADNGLGKTGEQELILDILYPPMVVIESKTREAEEGDTVTIRCNVTANPAPVTIEWLKENSPDFRYNGDVLTLTSVRADHAGNYICRAVNIMQSQGMERSERVGNSTVALLVRHRPGQAYITPNKPVVHVGNGVTLTCSANPPGWPVPQYRWFRDMDGEFSSTQKILAQGPQYSIPKAHLGNEGKYHCHAVNELGIGMMATIVLEIHQPPQFLAKLQQHMTRRVADTDYTVTCSAKGKPAPSVKWLKDAVEILPEENLYEVQTNPDQGLNGMVTVQSQLKFRGKARPNGNALVPGDRGLYTCLYQNEVNSANSSMQLRIEHEPIVLHQYNKVAFDIRETAEVVCKVQAYPKPEFQWQFGNNPSPLTMSSDGHYEISTTTDNNDIYTSVLKINSLTHSDYGEYTCRVANTLDTIRAPIRLQQKGPPEKPTNLRATEVGHNYVSLSWDPGFDGGLSKTKFFVSYRRVAMPREEQLIPDCATLANSNSAWVEVDCQRDIPCKVTALEQHQSYAFKVKALNPKSDSPYSSEIMVTTKVSRIPPPLQVTYEPNTRTLGIDVGATCLNLVAVVESMVNADSPMAAWEVVTTMDNLQLSGNGPTHKEKIIDRIIGARRVGGGRALGHTISEDEDDNGLNSLALEDENSPTVRVKLCLRTNPEHCGDYTDAEIGRPYIAEANALATPTLIAIIVSCVVFALFAGLILMFCRCKRNQSKKSAAAKDYEMDSVRPSIVAAQQNQAPPPYYPASGLDNKALEHSMDLALSMEDQKTALYATQNGYSYHPGSGVVGVGMGGGVVGVGVGGSVVSGMGGGVGGIGGSGVGVNGIPGLSAHTMPGNEWVNMGYMENNYSNSNNGGSVNSQDSLWQVKMSAAAVGNQQGMVQAPMNQYVEQQPAYGYDPLTHGGYGAVDDYAPYPHLTATPSQVGDEYHNLRNSQNPSRQDYCSDPYASVQKPKKRVDQHLADIIQDVTL
InterPro domains: - IPR036116: Fibronectin type III superfamily (homologous_superfamily) [735-864]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [44-735]
- IPR003961: Fibronectin type III (domain) [741-851]
- IPR013162: CD80-like, immunoglobulin C2-set (domain) [540-604]
- IPR007110: Immunoglobulin-like domain (domain) [37-736]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [38-852]
- IPR003598: Immunoglobulin subtype 2 (domain) [164-727]
- IPR003599: Immunoglobulin domain subtype (domain) [43-738]
- IPR051275: Cellular adhesion and signaling domain-containing protein (family) [38-326]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0050839 (cell adhesion molecule binding), GO:0005102 (signaling receptor binding), GO:0070851 (growth factor receptor binding), GO:0005154 (epidermal growth factor receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0022414 (reproductive process), GO:0048519 (negative regulation of biological process), GO:0048856 (anatomical structure development), GO:0023057 (negative regulation of signaling), GO:0009653 (anatomical structure morphogenesis), GO:0051241 (negative regulation of multicellular organismal process), GO:0071840 (cellular component organization or biogenesis), GO:0051239 (regulation of multicellular organismal process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0009791 (post-embryonic development), GO:0050793 (regulation of developmental process), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0048522 (positive regulation of cellular process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0051093 (negative regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0048869 (cellular developmental process), GO:0023056 (positive regulation of signaling), GO:0007275 (multicellular organism development), GO:0048584 (positive regulation of response to stimulus), GO:0007155 (cell adhesion), GO:0030029 (actin filament-based process), GO:0006950 (response to stress), GO:0001763 (morphogenesis of a branching structure), GO:0048585 (negative regulation of response to stimulus), GO:0032989 (cellular component morphogenesis), GO:0002165 (instar larval or pupal development), GO:0009968 (negative regulation of signal transduction), GO:0007552 (metamorphosis), GO:0048729 (tissue morphogenesis), GO:0044085 (cellular component biogenesis), GO:0051961 (negative regulation of nervous system development), GO:0048731 (system development), GO:0046533 (negative regulation of photoreceptor cell differentiation), GO:0048513 (animal organ development), GO:0009966 (regulation of signal transduction), GO:0032970 (regulation of actin filament-based process), GO:0010453 (regulation of cell fate commitment), GO:0035295 (tube development), GO:0009887 (animal organ morphogenesis), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0045595 (regulation of cell differentiation), GO:0016043 (cellular component organization), GO:0009790 (embryo development), GO:0009886 (post-embryonic animal morphogenesis), GO:0051128 (regulation of cellular component organization), GO:0010927 (cellular component assembly involved in morphogenesis), GO:0035239 (tube morphogenesis), GO:0009967 (positive regulation of signal transduction), GO:0048736 (appendage development), GO:0010648 (negative regulation of cell communication), GO:0009611 (response to wounding), GO:0098609 (cell-cell adhesion), GO:0061138 (morphogenesis of a branching epithelium), GO:0035107 (appendage morphogenesis), GO:0030036 (actin cytoskeleton organization), GO:0061061 (muscle structure development), GO:2000026 (regulation of multicellular organismal development), GO:0048598 (embryonic morphogenesis), GO:0009888 (tissue development), GO:0046843 (dorsal appendage formation), GO:0010646 (regulation of cell communication), GO:0045596 (negative regulation of cell differentiation), GO:0010647 (positive regulation of cell communication), GO:0007306 (egg chorion assembly), GO:0045664 (regulation of neuron differentiation), GO:0060562 (epithelial tube morphogenesis), GO:0008593 (regulation of Notch signaling pathway), GO:0048707 (instar larval or pupal morphogenesis), GO:0032956 (regulation of actin cytoskeleton organization), GO:0002009 (morphogenesis of an epithelium), GO:0016331 (morphogenesis of embryonic epithelium), GO:0048754 (branching morphogenesis of an epithelial tube), GO:0022607 (cellular component assembly), GO:0050768 (negative regulation of neurogenesis), GO:0048737 (imaginal disc-derived appendage development), GO:0035146 (tube fusion), GO:1901184 (regulation of ERBB signaling pathway), GO:1902533 (positive regulation of intracellular signal transduction), GO:0048563 (post-embryonic animal organ morphogenesis), GO:0007560 (imaginal disc morphogenesis), GO:0007444 (imaginal disc development), GO:2000027 (regulation of animal organ morphogenesis), GO:0007015 (actin filament organization), GO:0045747 (positive regulation of Notch signaling pathway), GO:1901185 (negative regulation of ERBB signaling pathway), GO:0022604 (regulation of cell morphogenesis), GO:0035120 (post-embryonic appendage morphogenesis), GO:0060284 (regulation of cell development), GO:0007423 (sensory organ development), GO:0035114 (imaginal disc-derived appendage morphogenesis), GO:0048644 (muscle organ morphogenesis), GO:0010454 (negative regulation of cell fate commitment), GO:0051960 (regulation of nervous system development), GO:0045229 (external encapsulating structure organization), GO:0045665 (negative regulation of neuron differentiation), GO:0042060 (wound healing), GO:0042659 (regulation of cell fate specification), GO:0098742 (cell-cell adhesion via plasma-membrane adhesion molecules), GO:0048569 (post-embryonic animal organ development), GO:0009996 (negative regulation of cell fate specification), GO:0033043 (regulation of organelle organization), GO:0007517 (muscle organ development), GO:0060429 (epithelium development), GO:0006996 (organelle organization), GO:0010721 (negative regulation of cell development), GO:0097435 (supramolecular fiber organization), GO:1902531 (regulation of intracellular signal transduction), GO:0009792 (embryo development ending in birth or egg hatching), GO:0060541 (respiratory system development), GO:0051493 (regulation of cytoskeleton organization), GO:0007472 (wing disc morphogenesis), GO:0007424 (open tracheal system development), GO:0007010 (cytoskeleton organization), GO:0090175 (regulation of establishment of planar polarity), GO:0035147 (branch fusion, open tracheal system), GO:0051017 (actin filament bundle assembly), GO:0050767 (regulation of neurogenesis), GO:0007476 (imaginal disc-derived wing morphogenesis), GO:0007391 (dorsal closure), GO:0035330 (regulation of hippo signaling), GO:0008360 (regulation of cell shape), GO:0042058 (regulation of epidermal growth factor receptor signaling pathway), GO:0046532 (regulation of photoreceptor cell differentiation), GO:0001700 (embryonic development via the syncytial blastoderm), GO:0035220 (wing disc development), GO:0007156 (homophilic cell adhesion via plasma membrane adhesion molecules), GO:0061572 (actin filament bundle organization), GO:0035332 (positive regulation of hippo signaling), GO:0060446 (branching involved in open tracheal system development), GO:0042059 (negative regulation of epidermal growth factor receptor signaling pathway), GO:0030038 (contractile actin filament bundle assembly), GO:0110116 (regulation of compound eye photoreceptor cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0009986 (cell surface), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0012505 (endomembrane system), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0070161 (anchoring junction), GO:0005938 (cell cortex), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0005769 (early endosome), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0005911 (cell-cell junction), GO:0005912 (adherens junction), GO:0097708 (intracellular vesicle)