Protein: Anoctamin (Q9V416)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Membrane; Multi-pass membrane protein
Sequence: MHGNEEVRDGVPFSEQQQSSEDVPDSTATTTATSTAGELGGGPRDGGEDDFTDDNNFESNLRRRKGKIISCAKETIENASRQLRRKVPYAGHLMTPRRLWLNKIPTQCDVVIEFPEDAPDEALRWLLARIRSQPPAGLGLLVQVKAHESTRRNAFYVSAPVNVLFKAAEEARLPKRLRPDLGGALREFTTRESHCFQQLRGDVGSTALFTSQERQWLVLQVLQGLRAGCSDIEALHGRAAVAEGQSIVATWQESGLITQVFPLHEPSSLTQLQTHWVKQIFAPQPLDDIAAYFGVKVALYFAWLGHYTCALGVPAVFGTILYCILWGKGQTAQDMGHVLFSLFNVAWASLYLEAWKRYSVELAFRWGTLSTPPELLEPPRPLYKGPLEENNVTGRLEPKEAPAWQRRAFRYLVSFPIIGCCLCVVFAVMFLMLRFQDWWDSKLPEESVLCCLSVIPKVLLAGAITLMDEAYFKLAVWLNDRENYRLQSKYENHLIAKVALFQFVNSFLSLFYIAFYLRDEEKLKEQLAGLLISRQIIGNLRESAIPYFLEQWKLAKLSFNMWGALSPTQNVTRSLAEELATAEAELKAESTGTPTKSQQPESSSKRNIGQAEIESSLYKYDGTFSDHLEMLVQMGYVVLFSAAFPLAGVCALINNLMEIRSDAFKLAHVHQRPFGQRVANIGTWQNALSILSLAAVIVNCALIGLSGQVSRLWPGLTTAQTIILIVTLEHIMLGLRQALTWLLPELPSWLAAEIARAEHCRREMQCKGTSPRPTPPTPQSTTSTQPEQEGPGGLQMESGANTTRDQSMESQVAEDILLYGQEFAGYGHNIEADVNIYENRDSSPDSPPSQTSTILIRPLHESTPPHGGASLTSLHQDGNGGACQSWVKKSQMFIPEIPPYLGYSVRNLTTFAGNSRKMQQHQKLQSGASASTLALNSAAYAARMQSMHIQEIPPFRKKSTDSADHTGSSASSSPQRTTMRQLSAQREPQQQTIPEIPPYKTRKISAESAMHLNMSDKLHIKLHAPEWMSRLKVNDNANLHRSIDCISKELGNSADTADILKPAPSWCNVAMRSGAPGSNLATPPASQHQQQIVASSSSSSGGGGSVFSPSGPGPAGASGVGISNSQSRPSVGALSNSSSGSSHKQQLKQQAKEEKERAKEEKERAKEEKERVKEKEKERLKEKEIEKAMEKEKEKDAQGAAASTSTAATDDEAKAAELAAKKSRLKQKLVKSARSVAIFSLKLKERRQREAEKAATIAVEHAKALAKLPMPQPVGGELSLIPIEQLIQIEDIIPAMKAASTSGATTSSSQAGPSTYHQQQHQQQHYHPPSNPHPHTDN
InterPro domains: - IPR049452: Anoctamin, transmembrane domain (domain) [289-756]
- IPR007632: Anoctamin (family) [91-771]
Interaction partners: - Liprin-gamma, isoform C
- Protein tipE
- Uncharacterized protein, isoform B
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0008509 (monoatomic anion transmembrane transporter activity), GO:0015103 (inorganic anion transmembrane transporter activity), GO:0015267 (channel activity), GO:0005216 (monoatomic ion channel activity), GO:0015108 (chloride transmembrane transporter activity), GO:0005253 (monoatomic anion channel activity), GO:0022839 (monoatomic ion gated channel activity), GO:0022836 (gated channel activity), GO:0005254 (chloride channel activity), GO:0005244 (voltage-gated monoatomic ion channel activity), GO:0061778 (intracellular chloride channel activity), GO:0022832 (voltage-gated channel activity), GO:0005247 (voltage-gated chloride channel activity), GO:0008308 (voltage-gated monoatomic anion channel activity), GO:0005229 (intracellular calcium activated chloride channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0006811 (monoatomic ion transport), GO:0015698 (inorganic anion transport), GO:0006821 (chloride transport), GO:0006812 (monoatomic cation transport), GO:0006820 (monoatomic anion transport), GO:0030001 (metal ion transport), GO:0006813 (potassium ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0098793 (presynapse), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0042734 (presynaptic membrane), GO:0098590 (plasma membrane region), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0097060 (synaptic membrane), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)