Protein: Homeobox protein php-3 (Posterior Hox protein paralog 3) (Q9XW88)
Organism: Caenorhabditis elegans
Function: Probable transcription factor, involved in posterior embryonic patterning, morphogenetic movements of the posterior hypodermis, and cell fate specification. May regulate expression of transcription factor dmd-3.
Subcellular location: Nucleus {ECO:0000255|RuleBase:RU000682}.
Sequence: MISVMQQMMNNSNMPPPFVKSSDSHETHDESPTSPFIKRSDSPATTSSAAAAAMQHNFWSTRAAQLQQSVSGSSGVSSGSSSSASNNLSRTQADNHSERGSDTASSPQVAPLPTSSGMSMPAAAAAGMYPFNAGRFPTEFNMMVNQSMYNDFYSNSLAASSWPYSYPQQYPFANYSMPSLDGNLNDGGQLEWTSSSHAMRKKRKPYTKAQTLELEKEFLYNTYVSKQKRWELAKYLHLTERQVKIWFQNRRMKDKKQKQRTSGDPTGMLMPPGLD
InterPro domains: - IPR001356: Homeodomain (domain) [197-261]
- IPR020479: Homeodomain, metazoa (domain) [221-255]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [188-258]
- IPR017970: Homeobox, conserved site (conserved_site) [232-255]
- IPR046333: Homeobox protein Hox-A10/abdominal-B-like (family) [37-262]
Interaction partners: - Homeobox protein ceh-40
- Homeobox protein ceh-20
- Homeobox protein unc-62
- Homeobox protein ceh-60
- Homeobox protein lin-39
- Homeobox protein egl-5
- Homeobox protein mab-5
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0019098 (reproductive behavior), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048522 (positive regulation of cellular process), GO:0019222 (regulation of metabolic process), GO:0007389 (pattern specification process), GO:0009893 (positive regulation of metabolic process), GO:0032504 (multicellular organism reproduction), GO:0007610 (behavior), GO:0045165 (cell fate commitment), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0003002 (regionalization), GO:0031325 (positive regulation of cellular metabolic process), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0018991 (oviposition), GO:0060255 (regulation of macromolecule metabolic process), GO:0009790 (embryo development), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009891 (positive regulation of biosynthetic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0022008 (neurogenesis), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0007399 (nervous system development), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0009954 (proximal/distal pattern formation), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0030182 (neuron differentiation), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0009952 (anterior/posterior pattern specification), GO:0010468 (regulation of gene expression), GO:0009792 (embryo development ending in birth or egg hatching), GO:1902680 (positive regulation of RNA biosynthetic process), GO:0048699 (generation of neurons), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0006357 (regulation of transcription by RNA polymerase II), GO:0045893 (positive regulation of DNA-templated transcription), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045944 (positive regulation of transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)