Protein: Transcription factor IND (Basic helix-loop-helix protein 40) (AtbHLH40) (bHLH 40) (Protein INDEHISCENT) (Transcription factor EN 120) (bHLH transcription factor bHLH040) (O81313)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription regulator required for seed dispersal. Involved in the differentiation of all three cell types required for fruit dehiscence. Acts as the key regulator in a network including SHP and ALC that controls specification of the valve margin. Works with ALC, SHP, and FUL to allow differentiation of the lignified valve layer, the spring-loaded mechanism of fruit that promotes opening. Regulates the expression of the YJ80 marker.
Subcellular location: Nucleus {ECO:0000305}.
Sequence: MENGMYKKKGVCDSCVSSKSRSNHSPKRSMMEPQPHHLLMDWNKANDLLTQEHAAFLNDPHHLMLDPPPETLIHLDEDEEYDEDMDAMKEMQYMIAVMQPVDIDPATVPKPNRRNVRISDDPQTVVARRRRERISEKIRILKRIVPGGAKMDTASMLDEAIRYTKFLKRQVRILQPHSQIGAPMANPSYLCYYHNSQP
InterPro domains: - IPR011598: Myc-type, basic helix-loop-helix (bHLH) domain (domain) [118-173]
- IPR045843: Transcription factor IND-like (family) [37-182]
- IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [119-177]
Interaction partners: - SNF1-related protein kinase regulatory subunit beta-2
- B3 domain-containing transcription factor NGA4
- Myosin-4
- B3 domain-containing transcription factor NGA2
- RNA polymerase II transcriptional coactivator KIWI
- Floral homeotic protein PISTILLATA
- Trihelix transcription factor PTL
- B3 domain-containing transcription factor NGA3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0003006 (developmental process involved in reproduction), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0009791 (post-embryonic development), GO:0090698 (post-embryonic plant morphogenesis), GO:0099402 (plant organ development), GO:1905393 (plant organ formation), GO:0048449 (floral organ formation), GO:1905392 (plant organ morphogenesis), GO:0090567 (reproductive shoot system development), GO:0048731 (system development), GO:0090696 (post-embryonic plant organ development), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0048608 (reproductive structure development), GO:0048437 (floral organ development), GO:0048438 (floral whorl development), GO:0080090 (regulation of primary metabolic process), GO:0048444 (floral organ morphogenesis), GO:0048367 (shoot system development), GO:0061458 (reproductive system development), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0048827 (phyllome development), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0048467 (gynoecium development), GO:0051252 (regulation of RNA metabolic process), GO:0048440 (carpel development), GO:0009908 (flower development), GO:0010468 (regulation of gene expression), GO:0090697 (post-embryonic plant organ morphogenesis), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)