Protein: Cytochrome c oxidase assembly protein COX11, mitochondrial (Q9Y6N1)
Organism: Homo sapiens (Human)
Function: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
Subcellular location: Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side
Sequence: MGGLWRPGWRCVPFCGWRWIHPGSPTRAAERVEPFLRPEWSGTGGAERGLRWLGTWKRCSLRARHPALQPPRRPKSSNPFTRAQEEERRRQNKTTLTYVAAVAVGMLGASYAAVPLYRLYCQTTGLGGSAVAGHASDKIENMVPVKDRIIKISFNADVHASLQWNFRPQQTEIYVVPGETALAFYRAKNPTDKPVIGISTYNIVPFEAGQYFNKIQCFCFEEQRLNPQEEVDMPVFFYIDPEFAEDPRMIKVDLITLSYTFFEAKEGHKLPVPGYN
InterPro domains: - IPR023471: Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily (homologous_superfamily) [140-272]
- IPR007533: Cytochrome c oxidase assembly protein CtaG/Cox11 (family) [75-273]
Interaction partners: - Protoheme IX farnesyltransferase, mitochondrial
- Cytochrome c oxidase subunit 2
- Cytochrome c oxidase subunit 3
- Cytochrome c oxidase subunit 1
- Protein SCO1 homolog, mitochondrial
- Cytochrome c oxidase copper chaperone
- Heme A synthase COX15
- Protein SCO2 homolog, mitochondrial
- Surfeit locus protein 1
- Cytochrome c oxidase assembly protein COX19
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0005515 (protein binding), GO:0016491 (oxidoreductase activity), GO:0009055 (electron transfer activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0065009 (regulation of molecular function), GO:0048523 (negative regulation of cellular process), GO:0009892 (negative regulation of metabolic process), GO:0050790 (regulation of catalytic activity), GO:0044092 (negative regulation of molecular function), GO:0062012 (regulation of small molecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0045912 (negative regulation of carbohydrate metabolic process), GO:0043086 (negative regulation of catalytic activity), GO:0010675 (regulation of cellular carbohydrate metabolic process), GO:0010906 (regulation of glucose metabolic process), GO:0010563 (negative regulation of phosphorus metabolic process), GO:0010677 (negative regulation of cellular carbohydrate metabolic process), GO:0006109 (regulation of carbohydrate metabolic process), GO:0051338 (regulation of transferase activity), GO:0051174 (regulation of phosphorus metabolic process), GO:0043549 (regulation of kinase activity), GO:0051348 (negative regulation of transferase activity), GO:0045936 (negative regulation of phosphate metabolic process), GO:0019220 (regulation of phosphate metabolic process), GO:0042325 (regulation of phosphorylation), GO:0033673 (negative regulation of kinase activity), GO:0042326 (negative regulation of phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005740 (mitochondrial envelope), GO:0019866 (organelle inner membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031966 (mitochondrial membrane), GO:0005743 (mitochondrial inner membrane)