wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Stathmin-3 (Q9JHU6)
Organism: Rattus norvegicus (Rat)
Function: Exhibits microtubule-destabilizing activity, which is antagonized by STAT3
Subcellular location: Golgi apparatus. Cell projection, growth cone. Cell projection, axon. Cytoplasm, cytosol
Sequence: MASTVSAYKEKMKELSVLSLICSCFYSQPHPNTIYQYGDMEVKQLDKRASGQSFEVILKSPSDLSPESPVLSSPPKRKDASLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSPLAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEMSG
InterPro domains: - IPR030514: Stathmin, conserved site (conserved_site) [75-117]
- IPR036002: Stathmin superfamily (homologous_superfamily) [39-175]
- IPR000956: Stathmin family (family) [4-180]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0150034 (distal axon), GO:0042995 (cell projection), GO:0044297 (cell body), GO:0005829 (cytosol), GO:0030427 (site of polarized growth), GO:0036477 (somatodendritic compartment), GO:0048471 (perinuclear region of cytoplasm), GO:0005737 (cytoplasm), GO:0043025 (neuronal cell body), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0030426 (growth cone), GO:0043227 (membrane-bounded organelle), GO:0043005 (neuron projection), GO:0043231 (intracellular membrane-bounded organelle), GO:0030424 (axon), GO:0005634 (nucleus)
Protein: Secreted beta-glucosidase SUN41 (Q59NP5)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Cell surface beta-glucosidase involved in cytokinesis, cell wall biogenesis, adhesion to host tissue, and biofilm formation; thus playing an important role in the host-pathogen interaction. Has hydrolytic activity on linear (1->3)-beta-D-glucans such as laminaribiose and other laminarioligosaccharides
Subcellular location: Secreted, cell wall. Secreted. Note=Secreted into the medium of cells growing as blastospores as well as those forming hyphae. Secretion is decreased in cells lacking VPS4
Sequence: MRFSQATVLAFAALSLAAPAFEADNKNIKREDCDKTSFHGHHKHKRAVAYDYAYVTVTVDGNGNPITTVSPVLSIETIAKSEETSSTSTSISSTTTIVQNDSLTSDEPKTLSLPSGTIKPSSFATESQSQSQSSSTGGSGSGSTNGIEGDLAAFEDPTEEFEDGVLSCSDFPSGQGVIPLDHLGFGGWSGIENSDGSTGGNCKEGSYCSYACQSGMSKTQWPEDQPSNGVSIGGLLCKNGKLYKSSTRSNYLCEWGVKKANVVNKLSETVAICRTDYPGTENMVIPTVVGGGSTSVITVVDQSTYYTWRGGATSAQYYVNNAGVSWEDGCVWGTPGSGVGNWAPLNFGAGYANGIAYLSLIPNPNNRDSLNFKVKIVGESGSTVSGSCSYANGKFNGNSDDGCTVGVTSGEADFVLYN
InterPro domains: - IPR005556: SUN family (family) [163-405]
- IPR051526: Secreted Beta-Glucosidase SUN (family) [1-417]
Interaction partners: - Probable circularly permuted 1,3-beta-glucanase TOS1
- Cell surface mannoprotein MP65
- Agglutinin-like protein 3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0071554 (cell wall organization or biogenesis), GO:0071555 (cell wall organization), GO:0016043 (cellular component organization), GO:0071852 (fungal-type cell wall organization or biogenesis), GO:0045229 (external encapsulating structure organization), GO:0031505 (fungal-type cell wall organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009986 (cell surface), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005576 (extracellular region), GO:0005618 (cell wall), GO:0009277 (fungal-type cell wall)
Protein: Synaptojanin-2-binding protein (Q9WVJ4)
Organism: Rattus norvegicus (Rat)
Function: Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction
Subcellular location: Mitochondrion outer membrane
Sequence: MNGRVDYLVSEEEINLTRGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKEDGAAARDGRLQEGDKILSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQHRLPVQNGPIVHRGDGEPSGVPVAVVLLPVFALTLVAVWAFVRYRKQL
InterPro domains: - IPR050614: Synaptic Scaffolding LAP/MAGUK Families (family) [12-102]
- IPR036034: PDZ superfamily (homologous_superfamily) [1-111]
- IPR001478: PDZ domain (domain) [13-100]
Interaction partners: - Ribosome-binding protein 1
- Synaptojanin-2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0071840 (cellular component organization or biogenesis), GO:0051640 (organelle localization), GO:0051646 (mitochondrion localization), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0048311 (mitochondrion distribution), GO:0007005 (mitochondrion organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009986 (cell surface)
Protein: Trace amine-associated receptor 13c (Q5QNP2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Olfactory receptor for medium length odd-chained diamines including cadaverine which is generated by bacterial decarboxylation of the basic amino acid lysine and contributes to the odor of decomposing tissue. Mediates pronounced innate aversion behavior to cadaverine
Subcellular location: Cell membrane; Multi-pass membrane protein
Sequence: MDLSSQEYDPSQFCFPAVNNSCLKGTHHVSTQTVVYLILASAMTVTVLGNSVVIISIAHFKQLQTPTNILVMSLALADLLLGLVVMPFSMIRSVDGCWYYGETFCLLHTGFDLFLTSVSIFHLIFIAVDRHQAVCFPLQYPTRITIPVAWVMVMISWSMAAFYSYGVVYSKANLEGLEEYIASVYCMGGCTLYFNALWSVLDTLLTFFLPCSVMVGLYARIFVVAKKHIKSITEANQNENENVFKNPRRSERKAAKTLGIVVGAFILCWLPFFINSLVDPYINFSTPYALFDAFGWLGYTNSTLNPIIYGLFYPWFRKTLSLIVTLRIFEPNSSDINLFTV
InterPro domains: - IPR050569: Trace Amine-Associated Receptor (family) [19-325]
- IPR009132: Trace amine associated receptor family (family) [56-292]
- IPR000276: G protein-coupled receptor, rhodopsin-like (family) [34-323]
- IPR017452: GPCR, rhodopsin-like, 7TM (domain) [49-309]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004930 (G protein-coupled receptor activity), GO:0008227 (G protein-coupled amine receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0042445 (hormone metabolic process), GO:0050793 (regulation of developmental process), GO:0051239 (regulation of multicellular organismal process), GO:0044237 (cellular metabolic process), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0040008 (regulation of growth), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0009991 (response to extracellular stimulus), GO:0031668 (cellular response to extracellular stimulus), GO:0040014 (regulation of multicellular organism growth), GO:0042594 (response to starvation), GO:0071496 (cellular response to external stimulus), GO:0048638 (regulation of developmental growth), GO:0033554 (cellular response to stress), GO:0007186 (G protein-coupled receptor signaling pathway), GO:0010570 (regulation of filamentous growth), GO:0009267 (cellular response to starvation), GO:0031669 (cellular response to nutrient levels), GO:0031667 (response to nutrient levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)
Protein: Transgelin (P31232)
Organism: Rattus norvegicus (Rat)
Function: Actin cross-linking/gelling protein
Subcellular location: Cytoplasm
Sequence: MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIVMQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPEGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVTKTDMFQTVDLFEGKDMAAVQRTVMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTDSQLQEGKHVIGLQMGSNRGASQAGMTGYGRPRQIIS
InterPro domains: - IPR001715: Calponin homology domain (domain) [24-137]
- IPR003096: Smooth muscle protein/calponin (family) [3-191]
- IPR050606: Calponin-like (family) [1-199]
- IPR000557: Calponin repeat (repeat) [175-200]
- IPR036872: CH domain superfamily (homologous_superfamily) [17-160]
Interaction partners: - Actin, aortic smooth muscle
- Myosin-10
- Myosin regulatory light polypeptide 9
- Smoothelin
- Myocardin
- Actin, gamma-enteric smooth muscle
- Actin, alpha skeletal muscle
- Actin, alpha skeletal muscle
- Actin, alpha skeletal muscle
- Actin, alpha skeletal muscle
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0060090 (molecular adaptor activity), GO:0044877 (protein-containing complex binding), GO:0030674 (protein-macromolecule adaptor activity), GO:0005515 (protein binding), GO:0051015 (actin filament binding), GO:0008092 (cytoskeletal protein binding), GO:0003779 (actin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0030029 (actin filament-based process), GO:0030036 (actin cytoskeleton organization), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0007010 (cytoskeleton organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0044297 (cell body), GO:0030054 (cell junction), GO:0099080 (supramolecular complex), GO:0098794 (postsynapse), GO:0036477 (somatodendritic compartment), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0043228 (non-membrane-bounded organelle), GO:0043025 (neuronal cell body), GO:0043197 (dendritic spine), GO:0097447 (dendritic tree), GO:0099572 (postsynaptic specialization), GO:0099081 (supramolecular polymer), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0014069 (postsynaptic density), GO:0098978 (glutamatergic synapse), GO:0030425 (dendrite), GO:0043005 (neuron projection), GO:0098984 (neuron to neuron synapse), GO:0099512 (supramolecular fiber), GO:0099513 (polymeric cytoskeletal fiber), GO:0032279 (asymmetric synapse), GO:0005856 (cytoskeleton), GO:0044309 (neuron spine), GO:0015629 (actin cytoskeleton), GO:0005884 (actin filament)
Protein: Tubulin alpha-3 chain (P05214)
Organism: Mus musculus (Mouse)
Function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin
Subcellular location: Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, flagellum axoneme
Sequence: MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDSVEAEAEEGEEY
InterPro domains: - IPR018316: Tubulin/FtsZ, 2-layer sandwich domain (domain) [248-393]
- IPR003008: Tubulin/FtsZ, GTPase domain (domain) [3-246]
- IPR017975: Tubulin, conserved site (conserved_site) [142-148]
- IPR000217: Tubulin (family) [2-439]
- IPR008280: Tubulin/FtsZ, C-terminal (homologous_superfamily) [246-437]
- IPR002452: Alpha tubulin (family) [18-438]
- IPR036525: Tubulin/FtsZ, GTPase domain superfamily (homologous_superfamily) [1-268]
- IPR037103: Tubulin/FtsZ-like, C-terminal domain (homologous_superfamily) [269-383]
- IPR023123: Tubulin, C-terminal (homologous_superfamily) [384-436]
Interaction partners: - Tubulin beta-4A chain
- Tubulin beta-4B chain
- Tubulin beta-6 chain
- Tubulin beta-1 chain
- Tubulin beta-2A chain
- Tubulin beta-3 chain
- Tubulin beta-5 chain
- Tubulin beta chain
- Tubulin beta chain
- Tubulin beta-5 chain
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0042221 (response to chemical), GO:0007017 (microtubule-based process), GO:0016043 (cellular component organization), GO:0000226 (microtubule cytoskeleton organization), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0034097 (response to cytokine), GO:0006996 (organelle organization), GO:0071310 (cellular response to organic substance), GO:0007010 (cytoskeleton organization), GO:0070670 (response to interleukin-4), GO:0071345 (cellular response to cytokine stimulus), GO:0071353 (cellular response to interleukin-4)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Phenyl-N-(sulfonatooxy)methanimidothioate sulfolyase (A1XLE2)
Organism: Lepidium sativum (Garden cress)
Function: Specifier protein that contributes to constitutive and herbivore-induced simple nitrile formation (By similarity). Catalyzes thiocyanate and simple nitrile formation from benzylglucosinolate in the presence of myrosinase. Converts also aliphatic glucosinolates to both epithionitriles and simple nitriles
Sequence: MALTLQGEWIKIEQKGGPAPGPRSSHCMAVVGDKLYMFGGELKPQFHLDKHLYVFDFKTNTWSIAEPKGEAPSLSCLGVRMVAVGTKIYIFGGRDENRNYSDFYSYDTVKKEWKFLTKLDEERVPEARSFPAIAADDNHVYIFGGVSKGGVQSTPFRFKSTIVYNIAEGTWSQLPNPGPDFEPRGGAGLAVIDKKLWVVCGFANSTSGGINDYNSNKVQYYDLVSGKWIEVKTSGVKPSGRSVFAYAVIGKQIVIYGGEIFRDENGHLGPGTMSNEGYALDTETLVWEKLVDGGEPMTPLGWTANCTGTVYGKTGLLMHGGKQPFNNRTDDFYFYSF
InterPro domains: - IPR015915: Kelch-type beta-propeller (homologous_superfamily) [3-337]
- IPR006652: Kelch repeat type 1 (repeat) [87-194]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030234 (enzyme regulator activity), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0046677 (response to antibiotic)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: BOS complex subunit TMEM147 (A0A8I3MKU8)
Organism: complex subunit TMEM147 {ECO:0000305};
Function: Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes. The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions. Also acts as a negative regulator of CHRM3 function, most likely by interfering with its trafficking to the cell membrane (By similarity). Negatively regulates CHRM3-mediated calcium mobilization and activation of RPS6KA1/p90RSK activity (By similarity). Regulates LBR localization to the nucleus inner membrane (By similarity)
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
Sequence: MTLFHFGNCFALAYFPYFITYKCSGLSEYNAFWKCVQAGVTYLFVQLCKMLFLATFFPTWEGGIYDFIGEFMKASVDVADLIGLNLVMSRNAGKGEYKIMVAALGWATAELIMSRCIPLWVGARGIEFDWKYIQMSIDSNISLVHYIVASAQVWMITRYDLYHTFRPAVLLLMFLSVYKAFVMETFVHLCSLGSWTALLARAVVTGLLALSTLALYVAVVNVHS
InterPro domains: - IPR019164: Transmembrane protein 147 (family) [1-220]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0051239 (regulation of multicellular organismal process), GO:0019222 (regulation of metabolic process), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0060627 (regulation of vesicle-mediated transport), GO:0051049 (regulation of transport), GO:0042127 (regulation of cell population proliferation), GO:0001817 (regulation of cytokine production), GO:0010941 (regulation of cell death), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0050764 (regulation of phagocytosis), GO:0080164 (regulation of nitric oxide metabolic process), GO:0070663 (regulation of leukocyte proliferation), GO:0043067 (regulation of programmed cell death), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:0042981 (regulation of apoptotic process), GO:0032944 (regulation of mononuclear cell proliferation), GO:0045428 (regulation of nitric oxide biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Transmembrane protein 160 (Q9NX00)
Organism: Homo sapiens (Human)
Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein
Sequence: MGGGWWWARAARLARLRFRRSLLPPQRPRSGGARGSFAPGHGPRAGASPPPVSELDRADAWLLRKAHETAFLSWFRNGLLASGIGVISFMQSDMGREAAYGFFLLGGLCVVWGSASYAVGLAALRGPMQLTLGGAAVGAGAVLAASLLWACAVGLYMGQLELDVELVPEDDGTASAEGPDEAGRPPPE
InterPro domains: - IPR026801: Transmembrane protein 160 (family) [1-187]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0071840 (cellular component organization or biogenesis), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0016043 (cellular component organization), GO:0031323 (regulation of cellular metabolic process), GO:0044085 (cellular component biogenesis), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0034248 (regulation of amide metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0006996 (organelle organization), GO:0051246 (regulation of protein metabolic process), GO:0010468 (regulation of gene expression), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0031326 (regulation of cellular biosynthetic process), GO:0042254 (ribosome biogenesis), GO:0006417 (regulation of translation), GO:0010608 (post-transcriptional regulation of gene expression), GO:2000112 (regulation of cellular macromolecule biosynthetic process), GO:0140694 (non-membrane-bounded organelle assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Transmembrane protein 18 (Q641M3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus membrane; Multi-pass membrane protein
Sequence: MTASNTKNASAIPIDKFSNVRITSIWTFLQSVDWSEPWLMALLAFHVFCFAFTLLSCKYYRIQICHFLLMVAMVYSAEYLNELAAMNWRSFSKFQYFDSKGMFISLVYSVPLLLNTVIIVAVWVWRTFSTMTELKILQLKRKAARENHKKTQ
InterPro domains: - IPR026721: Transmembrane protein 18 (family) [28-143]
Interaction partners: - Melanocortin receptor 4
- Golgi to ER traffic protein 4 homolog
- Glucosamine-6-phosphate isomerase
- Zinc finger protein 64
- Protein transport protein Sec16B isoform X1
- N-acetyltaurine hydrolase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0042592 (homeostatic process), GO:0048878 (chemical homeostasis), GO:0050794 (regulation of cellular process), GO:0010941 (regulation of cell death), GO:0055088 (lipid homeostasis), GO:0043067 (regulation of programmed cell death), GO:0042981 (regulation of apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0043229 (intracellular organelle), GO:0005635 (nuclear envelope), GO:0043227 (membrane-bounded organelle), GO:0031965 (nuclear membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)