Protein: Reelin (Q6Q144)
Organism: Bos taurus (Bovine)
Function: Not known
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Sequence: VFLKDGERKICTPYLDTTGYGNLRFYFVMGGICDPGDSHENDVALYAKTEGRKEHITLDTLSYSSYKVPSLVSVVINPDLQTPATKFCLRQKNHQGYNRNVWAVDFFHVLPVLPSTMSHMIQFSINLGCGTQQPGNSISLEFSTNHGRSWSLLHTECLPEICAGPHLPHSTIYSSENYSGWNRITIPLPNAALTRDTRIRWRQTXPILGNMWAIDNVYIGPSCLKFCSGRGQCTRHGCKCDPGFSGPACEMASQTFPMFISESFGSSRLSSYHNFYSIRGAEVSFGCGVLASGKALVFNKDGRRQLITSFLDSSQSRFLQFTLRLGSKSVLSTCKAPDQPGEGVLLHYSYDNGITWKLLEHYSYLXYHEPRIISVELPDDARQFGIQFRWWQPYHSSQGEDVWAIDEIIMTSVLFNSISLDFTNLVEVTQSLGFYLGNVQPYCGHDWTLCFTGDSKLASSMRYVETQSMQIGASYMIQFSLVMGCGQKYTPHIDNQVKLEYSTNHGLTWHLVQEECLPSMPSCQEFTSASIYHASEFTQWRRVIVLLPQKTWSSATRFRWSQSYYTAQDEWALDSIYIGQQCPNMCSGHGSCDRGMCRCDQGYQGTECHPEAALPSTIMSDFENPSAWESDWQEVIGGQIVKPEEGCGVISSGSSLYFSKAGKRQLVSWDLDTSWVDFVQFYIQIGGESSACNKPDSREEGVLLQYSNNGGIQWHLLAEMYFSDFSKPRFVYLELPAAAKTPCTRFRWWQPVFSGEDYDQWAVDDIIILSEKQKQIIPVVNPTLPQNFYEKPAFDYPMNQMSVWLMLANEGMVKNETFCSATPSAMVFGKSDGDRFAVTRDLTLKPGYVLQFKLNIGCANQFSSAAPVLLQYSHDAGMSWFLVKEGCYPASAGKGCEGNSRELSEPTMYHTGDFEEWTRITIVIPRSLASSKTRFRWIQESSSQKNVPPFALDGVYISEPCPSYCSGHGDCVSGVCFCDLGYTAAQGTCVSIVPNHSEMFDRFEGKLSPLWYKITGGQVGTGCGTLNDGKSLYFSGPGKREARTVPLDTRNIRLVQFYIQIGSKTSGITCIKPRARNEGLVVQYSNDNGILWHLLRELDFMSFLEPQIISIDLPRESKTPATAFRWWQPQHGKHSAQWALDDVLIGMNDSSQTGFQDKFDGSLDLQANWYRIQGGQVDIDCLSMDTALIFTENIGKPRYAETWDFHVSASTFLQFEMSMGCSKPFSDSHSVQLQYSLNNGRDWHLVTEECVPPTIGCLHYTESSIYTSERFQNWKRITVYLPLSTISPRTRFRWIQANYTLGADSWAIDNVVLASGCPWMCSGRGICDAGRCVCDRGFGGAYCVPVIPLPSILKDDFNXNLHPDLWPEVYGAERGNLNGETIKSGTSLIFKGEGLRMLISRDLDCTNTMYVQFSLRFIAKSTPERSHSILLQFSINGGITWHLMDEFYFPQTTNILFINVPLPYTAQTNATRFRLWQPYNNGKKEEIWIVDDFIIDGNNLNNPVMLLDTFDFGPRERQLVFLSWWYIGLYCPYSSKGAPEEDSAMVFVSNEVGEHSITTRDLNVNENTIIQFEINVGCSTDSSSADPVRLEFSRDFGATWHLLLPLCYHSSGHVSSLCSTEHHPSSTYHAGTTQGWRREVVHFGKLHLCGSVRFRWYQGFYSAGSQPVTWAIDNVYIGPQCEEMCNGHGSCINGTKCICDPGYSGPTCKISTKNPDFLKDDFEGQLESDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLMTRDLDLSHARFVQFFMRLGCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYIALEIPLKARSASTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTVLEDDFTTLDSRKWLLHPGGTKMPVCGSTGDALVFIEKASTRYVVTTDIAVNEDSFLQIDFAASCSVTDSCYAIELEYSIDLGLSWHPLIRDCLPTNVECSRYHLQRILVSDTFNKWTRITVPLPPYTRSQATRFRWHQPAPFDKQQTWAIDNVYIGDGCIDMCGGHGRCIQGNCVCDEQWGGLYCDEPETSLPTQLKDNFNRAPSNQNWLTVNGGKLSTVCGAVASGMALHFSGGCSRLLVTVDLNLTNAEFIQFYFMYGCLITPNNRNQGVLLEYSVNGGITWNLLMEIFYDQYSKPGFVNILLPPDAKEIATRFRWWQPRHDGLDQNDWAIDNVLISGSADQRTVMLDTFSSAPVPQHERSPADAGPVGRIAFDMFMEDKTAVNEHWLFHDDCTVERFCDSPDGVMICGSHDGREVYAVTPGLTPTEGWIMQFKISVGCKVSEKVTQNQIHVQYSTDFGVSWNYLVPQCLPADAKCSGSVSQPSVFFPTKGWKRITYPLPESLVGNPVRFRFYQKHSDMQWAIDNFYLGPECLDNCRGHGDCLKEQCICDPGYSGPNCYLTHTLKTFLKERFDSEEIKPDLWMSLEGGSTCTECGILAEDTALYFGGSTVRQAITQDLDLRGAKFLQYWGRIGSENNMTSCHRPICRKEGVVLDYSTDGGITWTLLHEMDYQKYISVRHDYILLPEEALTNTTRLRWWQPFVISNGLVVSGVERAQWALDNILIGGAEINPSQLVDTFDDEGTSHEENWSFYPNAVRTAGFCGNPSFHLYWPNKKKDKTHNALSSRELIIQPGYMMQFKIVVGCEATSCGDLHSVMLEYTKDARSDSWQLVQTQCLPSSSNSIGCSPFQFHEATIYNAVNSSSWKRITIQLPDHVSSSAHSSAGSRRAKKQRSRAGQSITCTSERLAPSSAVGTDTAPPVPSASAMKVSKAMTALFSVMTFPVTLKIILSRQESLRQTGKLFKVEYRKWLWAAGTLCPWGLALFYGCQIRQAATKPLDLTRASKIMFVLQIGSTSQTDSCNSDLSGPHAVDKAVLLQYSVNNGITWHVIAQHQPKDFTQAQRVSYNVPLEARMKGVLLRWWQPRHNGTGHDQWALDHVEVVLVSTRKQNYMMNFSRQHGLRHFYNRRRRSLRRYP
InterPro domains: - IPR013111: Epidermal growth factor-like domain, extracellular (domain) [1681-1708]
- IPR049419: Reelin, subrepeat B (repeat) [1-2973]
- IPR034968: Reelin (family) [630-2753]
- IPR036278: Sialidase superfamily (homologous_superfamily) [135-2650]
- IPR000742: EGF-like domain (domain) [222-2432]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0019538 (protein metabolic process), GO:0016043 (cellular component organization), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0090304 (nucleic acid metabolic process), GO:0006325 (chromatin organization), GO:0006259 (DNA metabolic process), GO:0022411 (cellular component disassembly), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006029 (proteoglycan metabolic process), GO:0018149 (peptide cross-linking), GO:0030203 (glycosaminoglycan metabolic process), GO:0006396 (RNA processing), GO:0043687 (post-translational protein modification), GO:0018410 (C-terminal protein amino acid modification), GO:0008380 (RNA splicing), GO:0006397 (mRNA processing), GO:0016071 (mRNA metabolic process), GO:0000375 (RNA splicing, via transesterification reactions), GO:0000377 (RNA splicing, via transesterification reactions with bulged adenosine as nucleophile)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)