Protein: DNA mismatch repair proteins mutS family domain-containing protein (Q9TXR4)
Organism: Caenorhabditis elegans
Function: Not known
Sequence: MSGGKDEASDKALLKILKSKSPNTIAIFSRGEYFSVYGDDATFVATNIFKSDVCVKTFTLSTDNSQQMKYISVNRGQYEKVVRETIVLLRCSVELYSSEQGEWKMTKRGSPGNTVDFEQEIGVSDQAPILAIYIHPGDDDNRVTLCAWDAGNVRIVISEYIDTPSFSQTEQCIFGLCPTEYILVNEGSVAPKAKKIASMFTRMEVHNKQQLKPKSQWSDVIESVHLDYKDEAEKQNENIKECLQILHSNAADEYSISEKYSIFNYGTHGNMLIDSCAVEALELFQLNYNYLEKSNNLTLYNVLNKCKTLPGEKLLRDWLSRPLCQIDHINERLDIVEALFENQTIRQKLRDSILARMPDCSQLARRLMRKCTLQDLNRFYQAATLLETVEMQLIQLSEAEQFAPSINRLLKSEITEILKKVERFQVLCDEFFDFDYEKENKEIRVRVDFVPEIQEISEKLEQMERVAEKLRKKYSAKFECDNLKLDKNSQYGFYFRVTLKEEKSIRKKDVHILETTKGSGVKFSVGELSDINDEFLEFHLKYTRAEEEVISMLCKKAEEFIPLIPAMAQLIATLDVFVSLSTFAATSSGIYTRPNLLPLGSKRLELKQCRHPVIEGNSEKPFIPNDVVLDKCRLIILTGANMGGKSTYLRSAALSILLAQIGSFVPCSSATISVVDGIFTRVGASDKQSQGISTFMAEMLDCSAILQRATKNSFVVIDELGRGTSTFDGFGIASAIAQDILNRIQCLSIFATHFHEMGKLAEQPGAVALQMGVQIENNEIHMLYKVFEGVAQCSFGLQVAKMVGIDENVINKAAQLLEGLEKKLVIDSKKKKELLESADIRQAILSLVK
InterPro domains: - IPR036678: MutS, connector domain superfamily (homologous_superfamily) [111-257]
- IPR000432: DNA mismatch repair protein MutS, C-terminal (domain) [632-821]
- IPR045076: DNA mismatch repair MutS (family) [15-831]
- IPR007696: DNA mismatch repair protein MutS, core (domain) [277-617]
- IPR007861: DNA mismatch repair protein MutS, clamp (domain) [449-539]
- IPR036187: DNA mismatch repair protein MutS, core domain superfamily (homologous_superfamily) [274-586]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [592-846]
- IPR007695: DNA mismatch repair protein MutS-like, N-terminal (domain) [17-117]
- IPR016151: DNA mismatch repair protein MutS, N-terminal (homologous_superfamily) [4-110]
- IPR011184: DNA mismatch repair Msh2-type (family) [1-849]
Interaction partners: - DNA mismatch repair protein S5 domain-containing protein
- DNA mismatch repair protein
- Mismatch repair endonuclease PMS2
- Exonuclease 1
- ERCC1-like central domain-containing protein
- XPA C-terminal domain-containing protein
- DNA repair endonuclease XPF
- Proliferating cell nuclear antigen
- DNA repair protein RAD51 homolog
- Flap endonuclease 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0022414 (reproductive process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0051321 (meiotic cell cycle), GO:0022402 (cell cycle process), GO:0006807 (nitrogen compound metabolic process), GO:0007049 (cell cycle), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0044237 (cellular metabolic process), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:1903046 (meiotic cell cycle process), GO:0048609 (multicellular organismal reproductive process), GO:0044238 (primary metabolic process), GO:0061982 (meiosis I cell cycle process), GO:0007276 (gamete generation), GO:0000706 (meiotic DNA double-strand break processing), GO:0007281 (germ cell development), GO:0044085 (cellular component biogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0046483 (heterocycle metabolic process), GO:0070192 (chromosome organization involved in meiotic cell cycle), GO:0045132 (meiotic chromosome segregation), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0051026 (chiasma assembly), GO:0007283 (spermatogenesis), GO:0007131 (reciprocal meiotic recombination), GO:0007059 (chromosome segregation), GO:1901360 (organic cyclic compound metabolic process), GO:0140013 (meiotic nuclear division), GO:0006139 (nucleobase-containing compound metabolic process), GO:0016043 (cellular component organization), GO:0009790 (embryo development), GO:0044260 (cellular macromolecule metabolic process), GO:0098813 (nuclear chromosome segregation), GO:0007127 (meiosis I), GO:0022607 (cellular component assembly), GO:0045143 (homologous chromosome segregation), GO:0090304 (nucleic acid metabolic process), GO:0006259 (DNA metabolic process), GO:0007129 (homologous chromosome pairing at meiosis), GO:0006996 (organelle organization), GO:0048232 (male gamete generation), GO:0009792 (embryo development ending in birth or egg hatching), GO:0048285 (organelle fission), GO:0006310 (DNA recombination), GO:0051276 (chromosome organization), GO:0000280 (nuclear division), GO:0035825 (homologous recombination), GO:0140527 (reciprocal homologous recombination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)