wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Probable LRR receptor-like serine/threonine-protein kinase At1g63430 (EC 2.7.11.1) (C0LGH8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Sequence: MRSKYFCSLALVLGLFFVSCDGFASNEVQALRRFKEAIYEDPLLVMSNWNDPNSDPCDWTGIYCSPSKDHVIKINISASSIKGFLAPELGQITYLQELILHGNILIGTIPKEIGNLKNLKILDLGNNHLMGPIPAEIGSLSGIMIINLQSNGLTGKLPAELGNLKYLRELHIDRNRLQGSLLVAGASGYQSKVYSSNSSANIAGLCKSLKVADFSYNFFVGNIPKCLENLPRTSFQGNCMQNKDLKHRSSSQCANAQLVKTHGSPSAAPKHQSAQMVAKHHRASKPKWLLALEIVTGSMVGLLLLVALFSAVHRWNNRSTLIIPWKKSSSEKEKFTVYVDSEMLKDVSRLTRQELEVACEDFSNIIGLSADSQIYKGTLKGGSEIAVISLCVKEEDWTGYLELYFQREVADLARLNHENTAKLLGYCKEISPFTRMLVFEYASNGTLYEHLHYGEAALVSWARRMKIVIGIARGLKYLHMELDPPFTISELSSNAIYLTEDFTPKLVDFECWKTILARSEKNLRNISSQGSICVLPNGMESRYLDVSGNIYAFGILLLEIVSGRPPYCKDKGFLIEWAKEFLEAPEAMSGLVDPELKHFNQEDLETVCEVASQCLNRDPTNNNNNHNKPSVQELCETLESRISLSISAELRSSSLAWAELALDS
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [339-621]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [26-265]
- IPR013210: Leucine-rich repeat-containing N-terminal, plant-type (domain) [25-65]
- IPR001245: Serine-threonine/tyrosine-protein kinase, catalytic domain (domain) [364-569]
- IPR001611: Leucine-rich repeat (repeat) [95-140]
- IPR000719: Protein kinase domain (domain) [360-642]
Interaction partners: - Probable galacturonosyltransferase 10
- Putative disease resistance protein At1g50180
- Cyclic nucleotide-gated ion channel 11
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0032502 (developmental process), GO:0050896 (response to stimulus), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0009605 (response to external stimulus), GO:0009856 (pollination), GO:0048856 (anatomical structure development), GO:0044706 (multi-multicellular organism process), GO:0042221 (response to chemical), GO:0003006 (developmental process involved in reproduction), GO:0010183 (pollen tube guidance), GO:0042330 (taxis), GO:0048868 (pollen tube development), GO:0006935 (chemotaxis), GO:0050918 (positive chemotaxis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Diuretic hormone 44 receptor 2, isoform A (IP10431p) (Q4V3E9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Sequence: MADDDLRALVDSLDDASQEDLAKVIANFSVDMLQRASALIGAQQGSSGGQLQNRTLQCQQQQQREEEQASLEALASGGKRILQCPSSFDSVLCWPRTNAGSLAVLPCFEEFKGVHYDTTDNATRFCFPNGTWDHYSDYDRCHQNSGSIPVVPDFSPNVELPAIIYAGGYFLSFATLVVALIIFLSFKDLRCLRNTIHANLFLTYITSALLWILTLFLQVITTESSQAGCITLVIMFQYFYLTNFFWMFVEGLYLYTLVVQTFSSDNISFIIYALIGWGCPAVCILVWSIAKAFAPHLENEHFNGLEIDCAWMRESHIDWIFKVPASLALLVNLVFLIRIMWVLITKLRSAHTLETRQYYKASKALLVLIPLFGITYLLVLTGPEQGISRNLFEAIRAFLISTQGFFVALFYCFLNSEVRQTLRHGFTRWRESRNIHRNSSIKNRRHRASKDYSLRSRTESLRLTSTSPIPTGHYE
InterPro domains: - IPR001879: GPCR, family 2, extracellular hormone receptor domain (domain) [57-150]
- IPR017983: GPCR, family 2, secretin-like, conserved site (conserved_site) [84-418]
- IPR000832: GPCR, family 2, secretin-like (family) [161-414]
- IPR036445: GPCR family 2, extracellular hormone receptor domain superfamily (homologous_superfamily) [43-169]
- IPR050332: G-protein coupled receptor 2 (family) [51-451]
- IPR017981: GPCR, family 2-like, 7TM (domain) [161-415]
- IPR002001: GPCR, family 2, diuretic hormone receptor (family) [107-462]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0009628 (response to abiotic stimulus), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0009755 (hormone-mediated signaling pathway), GO:0070887 (cellular response to chemical stimulus), GO:0007186 (G protein-coupled receptor signaling pathway), GO:0006970 (response to osmotic stress), GO:0071495 (cellular response to endogenous stimulus), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0032870 (cellular response to hormone stimulus), GO:0071310 (cellular response to organic substance), GO:0009651 (response to salt stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: NADH-cytochrome b5 reductase (EC 1.6.2.2) (Q95T90)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MARIVESNFVPLAVGVVAVLAGALIVHYLLNKKSTKPRREPNRTARLRTLVDPNDKYLLPLIEKENLSHDTRRFQFGLPSKQHVLGLPVGQHIHLIATIDNELIIRPYTPISSDEDVGYVDLVVKVYFKDSHPKFPAGGKMTQHLEQLELGDKISFRGPSGRLQYLGNGTFSIKKLRKDPPKHVTAKRVNMIAGGTGITPMLQLAREVLKRSDKDKTELALLFANQSEKDILLRAELDELAQKHPDQFKIWYTVDKANEGELQ
InterPro domains: - IPR001834: NADH:cytochrome b5 reductase-like (family) [31-258]
- IPR017938: Riboflavin synthase-like beta-barrel (homologous_superfamily) [49-168]
- IPR001433: Oxidoreductase FAD/NAD(P)-binding (domain) [191-260]
- IPR017927: FAD-binding domain, ferredoxin reductase-type (domain) [54-166]
- IPR001709: Flavoprotein pyridine nucleotide cytochrome reductase (domain) [106-240]
- IPR008333: Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain (domain) [59-165]
- IPR039261: Ferredoxin-NADP reductase (FNR), nucleotide-binding domain (homologous_superfamily) [152-262]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0005515 (protein binding), GO:0016491 (oxidoreductase activity), GO:0016651 (oxidoreductase activity, acting on NAD(P)H), GO:0016653 (oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0032879 (regulation of localization), GO:0010883 (regulation of lipid storage)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0012505 (endomembrane system)
Protein: Evasin-1 (EVA1) (P0C8E7)
Organism: Rhipicephalus sanguineus (Brown dog tick) (Ixodes sanguineus)
Function: Salivary chemokine-binding protein which shows chemokine neutralizing activity and binds to host chemokines CCL3, CCL4 and CCL18. Binds to CCL3 with 1:1 stoichiometry.
Subcellular location: Secreted {ECO:0000305}.
Sequence: MTFKACIAIITALCAMQVICEDDEDYGDLGGCPFLVAENKTGYPTIVACKQDCNGTTETAPNGTRCFSIGDEGLRRMTANLPYDCPLGQCSNGDCIPKETYEVCYRRNWRDKKN
InterPro domains: - IPR045797: Evasins Class A (family) [32-104]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019955 (cytokine binding), GO:0019956 (chemokine binding), GO:0019957 (C-C chemokine binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0023057 (negative regulation of signaling), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0040013 (negative regulation of locomotion), GO:0023051 (regulation of signaling), GO:0065009 (regulation of molecular function), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0040012 (regulation of locomotion), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:2000145 (regulation of cell motility), GO:0010469 (regulation of signaling receptor activity), GO:0050922 (negative regulation of chemotaxis), GO:0010646 (regulation of cell communication), GO:0050920 (regulation of chemotaxis), GO:0044092 (negative regulation of molecular function), GO:0009966 (regulation of signal transduction), GO:0032101 (regulation of response to external stimulus), GO:0051098 (regulation of binding), GO:2000146 (negative regulation of cell motility), GO:0032102 (negative regulation of response to external stimulus), GO:0051100 (negative regulation of binding), GO:0030334 (regulation of cell migration), GO:0043393 (regulation of protein binding), GO:0030336 (negative regulation of cell migration), GO:1900120 (regulation of receptor binding), GO:0032091 (negative regulation of protein binding)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Cycloartenol synthase LCA (EC 5.4.99.8) (A0A125SXN3)
Organism: Lycopodium clavatum (Stag's-horn clubmoss)
Function: Oxidosqualene cyclase involved in the biosynthesis of cycloartenol.
Sequence: MWSLKIAEGGGPWMSSLNDHVGRQIWQYDDNGGTPQERSAIDALQAQFTRNRHDVRHSSDSIMRFQFSKDNPLPPLPLQVKVKGHEQLTRDIVEKTLRRALRFYSTIQANDGHWPGDYGGPMFLMPGLVITLYITGALRVILSEQHQLEMCRYLYNHQNNDGGWGLHIEGHSTMFGTILTYVTLRLLNQGSGAHAAMEKARAWILDHGGATAAPSWGKFWLAALGIFDWSGVDPLPPEMWLLPYILPVYPGRMWCHCRMVYLPMSYIYGRRYSSPLTKLTSDIRNEIYVVPYEEVNWDSARNDCAREDLYYPHPFLQDLLWATLHKCVEPILMHWPGSLLRQRALAMVIEHIHYKDENTRYVCIGPVNKVINMLCCWVENPNSEAFKKHLPRVLDYLWLAEDGMKMQGYNGTQLWDTAFAVQALVSTQLLDECGSMLKKAHHYIERSQVQEDCAGDLRRWFRHISKGAWPFSTRDHGWPISDCSSEGLKASLELSSLSGDLVGDPIPAQRLYDCVNVILSYQNPNGGIATYESTRSYAWLELLNPAETFGDIVIDYPCVECTSACVQALAAFKRKYPEHRSKEIATTIRQGSMYIKNVQRSDGSWYGSWGVCFTYGTWFGIMGLLASGETYSTSASLRNACSFLLSKQLPSGGWGESYLSSQDKTYTHLEGDEAHLVNTSWAMLALIASGQVERDPTPLHKAXVLLVNAQFENGDYPQQEIIGVFNRNCMISYSAYRNIFPIWALGAYQCKVLGH
InterPro domains: - IPR008930: Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid (homologous_superfamily) [120-753]
- IPR032697: Squalene cyclase, N-terminal (domain) [99-383]
- IPR032696: Squalene cyclase, C-terminal (domain) [414-749]
- IPR018333: Squalene cyclase (family) [1-753]
- IPR002365: Terpene synthase, conserved site (conserved_site) [602-616]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016853 (isomerase activity), GO:0016866 (intramolecular transferase activity), GO:0031559 (oxidosqualene cyclase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0006720 (isoprenoid metabolic process), GO:0008299 (isoprenoid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0006721 (terpenoid metabolic process), GO:0016114 (terpenoid biosynthetic process), GO:0006722 (triterpenoid metabolic process), GO:0016104 (triterpenoid biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005811 (lipid droplet)
Protein: Pentatricopeptide repeat-containing protein At3g13150 (Q9LK58)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MSKVGSSLYSRLHGIFKESSIATAKSAKPRSQTKSTKFPSKLKASTASVGDGGQSSNDAKDSKNSKLTQKVEKFKRSCESESFRQVHGLYSAFIRRLREAKKFSTIDEVLQYQKKFDDIKSEDFVIRIMLLYGYSGMAEHAHKLFDEMPELNCERTVKSFNALLSAYVNSKKLDEAMKTFKELPEKLGITPDLVTYNTMIKALCRKGSMDDILSIFEELEKNGFEPDLISFNTLLEEFYRRELFVEGDRIWDLMKSKNLSPNIRSYNSRVRGLTRNKKFTDALNLIDVMKTEGISPDVHTYNALITAYRVDNNLEEVMKCYNEMKEKGLTPDTVTYCMLIPLLCKKGDLDRAVEVSEEAIKHKLLSRPNMYKPVVERLMGAGKIDEATQLVKNGKLQSYFRYLPDLSAGKKKTTSSPVSSSAKTTSTPVSSSPDTSSFLLSLSLAADSSSSDSDSSSPDSSSSVSSSPDSSSSVSSSPDSYSSFSSSPDSSSSVSSSLFSSSRENSSSPDYSNSVSSSLDYSGSVSSSSDYSSSVFPSANSSSSSSGLLDD
InterPro domains: - IPR050667: Pentatricopeptide repeat-containing protein (family) [33-393]
- IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [60-432]
- IPR002885: Pentatricopeptide repeat (repeat) [131-366]
Interaction partners: - At2g20720
- Pentatricopeptide repeat
- Endoplasmic reticulum transmembrane protein
- Vacuolar protein sorting-associated 9A-like protein
- Pentatricopeptide repeat-containing protein At1g02370
- H/ACA ribonucleoprotein complex non-core subunit NAF1
- Transcription factor EMB1444
- Pentatricopeptide repeat-containing protein At1g06270
- At5g17180
- Endoplasmic reticulum transmembrane protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0007276 (gamete generation), GO:0048229 (gametophyte development), GO:0048235 (pollen sperm cell differentiation), GO:0030154 (cell differentiation), GO:0009555 (pollen development), GO:0048232 (male gamete generation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Transmembrane protein (DUF2215) (Q0WVK0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Nucleus inner membrane {ECO:0000256|ARBA:ARBA00004575}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004575}; Nucleoplasmic side {ECO:0000256|ARBA:ARBA00004575}.
Sequence: MSDSSSVIVRSSNFIVVILFLNLVTFFSLVSSNELVFAVGETGSLQVTPRTEVIYSPGLKRGITSICERLHIHGLQRRLEHIDRYAHSLKLTLLSNNASNSIDVCFHRNSSRAIGMCPDNQWKRVSKGLPWVGIMSPFDYKILDIRTFGGSSNVSTVELVAKQEFFIYRIVFLIMGIVLLSLASRLSKSVAFYYIGAMSIGIVILVTLIINQGIKRLPTRGKSRFQLFFYSSMIGVGGYFLQYIRGLVQDLLMQIEISEDLYIPLAILLVVFVFMLGAWSGFWTVKKFVVTKDGSVDISTSIFVSWSIRAFAVALILQSSLDPLLAGGALITGILISLILKSISRKLLAQRIYEQDDETESCSPGLIHATSFASPLPRGSNKKLRTVPLSESDIFPSSFHKTPEGRRKLTKEELQKFTKESTENALKELVSSPGFGEWAVKNAKRITVNPIKESSSK
InterPro domains: - IPR019358: NEMP family (family) [162-441]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0001666 (response to hypoxia), GO:0016043 (cellular component organization), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0070482 (response to oxygen levels), GO:0071456 (cellular response to hypoxia), GO:0006325 (chromatin organization), GO:0071453 (cellular response to oxygen levels), GO:0036293 (response to decreased oxygen levels), GO:0036294 (cellular response to decreased oxygen levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005635 (nuclear envelope), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031965 (nuclear membrane), GO:0019866 (organelle inner membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0005637 (nuclear inner membrane), GO:0005634 (nucleus)
Protein: Tubby-like F-box protein 7 (AtTLP7) (Q93VI8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MPLSRSLLSRRISNSFRFHQGETTTAPESESIPPPSNMAGSSSWSAMLPELLGEIIRRVEETEDRWPQRRDVVTCACVSKKWREITHDFARSSLNSGKITFPSCLKLPGPRDFSNQCLIKRNKKTSTFYLYLALTPSFTDKGKFLLAARRFRTGAYTEYIISLDADDFSQGSNAYVGKLRSDFLGTNFTVYDSQPPHNGAKPSNGKASRRFASKQISPQVPAGNFEVGHVSYKFNLLKSRGPRRMVSTLRCPSPSPSSSSAGLSSDQKPCDVTKIMKKPNKDGSSLTILKNKAPRWHEHLQCWCLNFHGRVTVASVKNFQLVATVDQSQPSGKGDEETVLLQFGKVGDDTFTMDYRQPLSAFQAFAICLTSFGTKLACE
InterPro domains: - IPR025659: Tubby-like, C-terminal (homologous_superfamily) [96-379]
- IPR000007: Tubby, C-terminal (domain) [105-379]
- IPR018066: Tubby, C-terminal, conserved site (conserved_site) [307-379]
Interaction partners: - Probable ADP-ribosylation factor GTPase-activating protein AGD13
- Probable peroxygenase 5
- Protein PLANT CADMIUM RESISTANCE 11
- Shaggy-related protein kinase beta
- F-box protein At3g62230
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0019222 (regulation of metabolic process), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0043207 (response to external biotic stimulus), GO:0009620 (response to fungus), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: T-cell leukemia translocation-altered gene protein (T-cell leukemia translocation-associated gene protein) (P57738)
Organism: Homo sapiens (Human)
Function: May be required for cellular fusion during osteoclastogenesis.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Sequence: MAESWSGQALQALPATVLGALGSEFLREWEAQDMRVTLFKLLLLWLVLSLLGIQLAWGFYGNTVTGLYHRPGLGGQNGSTPDGSTHFPSWEMAANEPLKTHRE
InterPro domains: - IPR016560: T-cell leukemia translocation-altered gene protein (family) [1-103]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0071840 (cellular component organization or biogenesis), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0016043 (cellular component organization), GO:0051668 (localization within membrane), GO:0045184 (establishment of protein localization), GO:0008104 (protein localization), GO:0006996 (organelle organization), GO:0010256 (endomembrane system organization), GO:0090150 (establishment of protein localization to membrane), GO:0061024 (membrane organization), GO:0072657 (protein localization to membrane), GO:0051205 (protein insertion into membrane), GO:0033365 (protein localization to organelle), GO:0007029 (endoplasmic reticulum organization), GO:0045048 (protein insertion into ER membrane), GO:0071816 (tail-anchored membrane protein insertion into ER membrane)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)