Protein: Histone acetyltransferase (EC 2.3.1.48) (Q8III2)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU361211}.
Sequence: MVLGGKNENKVNVIKGAGSIGKYIMKENGSKIKEVGEWNNSSENENSDNNNNDREDNIKEKVDNNNKNDDNNNNDREDNIKEKVDNNNNNDDNNNDNNNNNKSDNNNNKSDNNNNKSDNYNNKIGDVSNIPSTNTSTVSNKIQGKGSVSYKSKEKTGDHSSNNKNTKGNNNKVRTSGKVINSLSKYSDSYALIFPNALPVKQVLWGLDPLNKVWRYCSIVYARPKNKVLNDTNFMFPLNMNKNEIINKVNNELNNNNSVSMSEGDYDYYVHWEKFDRRLDCWLAYENLRLLDKEPDDGLPLIKDNDNVSDHEHAGIDKEYLREHEENTKLKTINQIRFGKYLIDTWYFSPYPKEYQNIDILYICEFCLSFFKEYSELKRHIEKCEIRHPPGNEIYREEKISIFEIDGSYFRIYCENLCFLSKLFLDHKTLKHRVNLFLFYVITEYDEYGYHITGYFSKEKYSKNNVSCILTLPQHQKKGYGKFLINFSYFLSQTEKRTGTPERPLSDLGVASYMAYWYETILKVLINYEQLSIQELSEITSIETNDIISCLEEKDIFKNSLNGLDSFYYINPKQLEFILNKLKQTNNTQLSKNKLHWVSYDYYLALYE
InterPro domains: - IPR040706: MYST, zinc finger domain (domain) [331-384]
- IPR016181: Acyl-CoA N-acyltransferase (homologous_superfamily) [331-587]
- IPR002717: Histone acetyltransferase domain, MYST-type (domain) [328-599]
- IPR025995: RNA binding activity-knot of a chromodomain (domain) [260-289]
- IPR016197: Chromo-like domain superfamily (homologous_superfamily) [190-292]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [505-587]
- IPR050603: MYST family histone acetyltransferases (family) [250-599]
Interaction partners: - DNA methyltransferase 1-associated protein 1, putative
- Enhancer of polycomb-like protein
- PI3K/PI4K catalytic domain-containing protein
- Zinc finger protein, putative
- Histone H4
- Bromodomain protein, putative
- Histone H2A
- Histone H3-like centromeric protein CSE4
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0061733 (peptide-lysine-N-acetyltransferase activity), GO:0016746 (acyltransferase activity), GO:0004402 (histone acetyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016407 (acetyltransferase activity), GO:0016410 (N-acyltransferase activity), GO:0010485 (histone H4 acetyltransferase activity), GO:0008080 (N-acetyltransferase activity), GO:0034212 (peptide N-acetyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0050793 (regulation of developmental process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0006793 (phosphorus metabolic process), GO:0045595 (regulation of cell differentiation), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:0006796 (phosphate-containing compound metabolic process), GO:0043412 (macromolecule modification), GO:0043543 (protein acylation), GO:0018193 (peptidyl-amino acid modification), GO:0016310 (phosphorylation), GO:0006473 (protein acetylation), GO:0018205 (peptidyl-lysine modification), GO:0018394 (peptidyl-lysine acetylation), GO:0006475 (internal protein amino acid acetylation), GO:0018393 (internal peptidyl-lysine acetylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)