Protein: Multidrug resistance-associated protein 1 (G5EFP3)
Organism: Caenorhabditis elegans
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Sequence: MEPNLQAKLKGIDAFCGERYWDPAVWNASTVPILSQCYQHTTLVWFPTAIVFLLAPILTAQIFYRRPNPIPWTRRIQLKIGLACILIADSLSLFTVAIYETLFQGFPYAVDFVYPLTLCLAMVVLTALIVSCRNYGIVTSGGLFISWLVFTISAIPELLYWIQQIVNPAEAWNWIDYPRCIAFFIWFFCCAFETYLHCYADASPEGYKYLSAARNPSPETTSSFLNRITMWWFNSLCSLGVKKPLEVSDLYSLNEADTSNLLVPKWYNLWDKQSKKFEETAARRRIGSNASRTNRRRTSSNDTTPLLNDQSTDDYGSVPAGQSTQKMPSIIWTLFLMFKWDVITAMFVKLLSDVLLFCNPLLLKSLIRFTEELERPMWQGVVLAFTMFFSAELSSILLSHYFYLMYRVGTRVQTCLTAAVYRKTLRLSNAARREKTVGEIVNLMAIDVDRFQQITPQTMQYWSNPFQIGLALFLLFQQLGVSVFSGVAVMVLLFPINFVITMIIRKWQIAQMYYKDERTKMVNEVLNGIKVIKLYAWEPPMEQVIEDLREQELGLIKKAAFLRTFSDMLNTASPFLVALSTFATFIYIDPKNVLTPEIAFVSLTLFNQLRSPMSQVAELITQTVQVVVSNRRLKEFLVSEELNVEAIDHRARDNNDVICLKEACLSWESAEHQPVPTLTNISFSVNRGQLVTIVGRVGAGKSSMLQALMGEMEKLSGSISMHGRLCYVPQQPWMQNNTLRQNITFGKQFDEYFYSRVLDACALYRDLQILPLGDNTEIGEKGINLSGGQKARISLARAVYQNHDIYLLDDPMSAVDAHVGSQLFGSVIGPEGMLRNKTRILVTNELSFLEKSDLIIVMNEGKIEYSGKYDDLMQQGAFEQLLIECEKEERERREAEASADEDDENSEPGGIMIGGDSDFEYDDDVMASPIIDHVLGTSHMSTVSGIINRRRISTSTHKQRRRLSTTKSHTHSITSASTQTRQLTGTERVETGRVKMDTYYKYFGAMGMSIAVLFVLGMTTSTIFSMGRNLWLTDWSNDNAARSGSNTTGQPIAIRLGVYAGLGFSEIILLFIGMLSLLYGGVSASRNLHAPLMRNLFRVPMAFYDTTPFGRILNRIGKDIETVDVLLPFNVQFFAQCLLQVVSTLIIIMISTPVFGIVIIPLSVMYLMVMRYYIATSRQLKRLESITRSPIYSHLSESIQGSATIRAYHLVDRFCKLSETKVDSHVQCRYLNYVANRWLSVRLEFIGNCIVLFSALFAALTRTTTTSGVIGLSVSYALNITTVLNFAVRQITKLETNIVSVERVKEYAETETEAEWKSEPGKEPPQNWPSEGRIVMNNYSARYRPGLNLVVKQLNVEIKPHEKVGIVGRTGAGKSSVTLSLFRIIEAAEGQIVVDGINLAEIGLHDLRSNLTIIPQDPVLFSGTLRFNLDPFNHYSDGDIWKTLEMANLKEFATAHNEQLNYIITEGGDNISVGQRQLVCLARALLRKTRVLILDEATAAVDVSTDALIQKTIREEFANATVLTIAHRLNTIMDYDRIIVLNDGKVGEFDSPANLLSNRNSEFYSMAKRAGLI
InterPro domains: - IPR017871: ABC transporter-like, conserved site (conserved_site) [785-1485]
- IPR036640: ABC transporter type 1, transmembrane domain superfamily (homologous_superfamily) [320-1314]
- IPR005292: Multi drug resistance-associated protein (family) [17-1572]
- IPR003593: AAA+ ATPase domain (domain) [687-1545]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [662-1568]
- IPR003439: ABC transporter-like, ATP-binding domain (domain) [660-1568]
- IPR050173: ATP-binding cassette transporter C-like (family) [221-1568]
- IPR011527: ABC transporter type 1, transmembrane domain (domain) [343-1296]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0140657 (ATP-dependent activity), GO:0042626 (ATPase-coupled transmembrane transporter activity), GO:0022857 (transmembrane transporter activity), GO:0140359 (ABC-type transporter activity), GO:0090482 (vitamin transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0015399 (primary active transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0035966 (response to topologically incorrect protein), GO:0051788 (response to misfolded protein), GO:0071310 (cellular response to organic substance), GO:0035967 (cellular response to topologically incorrect protein), GO:0071218 (cellular response to misfolded protein)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0005773 (vacuole), GO:0031090 (organelle membrane), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0005774 (vacuolar membrane), GO:0098588 (bounding membrane of organelle), GO:0005764 (lysosome), GO:0098852 (lytic vacuole membrane), GO:0005765 (lysosomal membrane)