Protein: Zinc finger protein 385A (F8VRY0)
Organism: Homo sapiens (Human)
Subcellular location: Nucleus
Sequence: MQPPLDLKQILPFPLEPAPTLGLFSNYSTMDPVQKAVLSHTFGGPLLKTKRPVISCNICQIRFNSQSQAEAHYKGNRHARRVKGIEAAKTRGREPGVREPGDPAPPGSTPTNGDGVAPRPVSMENGLGPAPGSPEKQPGSPSPPSIPETGQGVTKGEGGTPAPASLPGGSKEEEEKAKRLLYCALCKVAVNSLSQLEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGE
InterPro domains: - IPR003604: Matrin/U1-C-like, C2H2-type zinc finger (domain) [51-212]
- IPR051845: Zinc finger protein 385 (family) [1-229]
- IPR013087: Zinc finger C2H2-type (domain) [54-205]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [11-211]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0002039 (p53 binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048519 (negative regulation of biological process), GO:0023056 (positive regulation of signaling), GO:0023057 (negative regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0060548 (negative regulation of cell death), GO:0080134 (regulation of response to stress), GO:0080135 (regulation of cellular response to stress), GO:0009966 (regulation of signal transduction), GO:2001022 (positive regulation of response to DNA damage stimulus), GO:2001021 (negative regulation of response to DNA damage stimulus), GO:0010941 (regulation of cell death), GO:0010646 (regulation of cell communication), GO:0010647 (positive regulation of cell communication), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:2001234 (negative regulation of apoptotic signaling pathway), GO:1902532 (negative regulation of intracellular signal transduction), GO:2001233 (regulation of apoptotic signaling pathway), GO:2001020 (regulation of response to DNA damage stimulus), GO:1902230 (negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage), GO:1902533 (positive regulation of intracellular signal transduction), GO:1902531 (regulation of intracellular signal transduction), GO:2001242 (regulation of intrinsic apoptotic signaling pathway), GO:0042981 (regulation of apoptotic process), GO:1901796 (regulation of signal transduction by p53 class mediator), GO:0043066 (negative regulation of apoptotic process), GO:2001243 (negative regulation of intrinsic apoptotic signaling pathway), GO:1901797 (negative regulation of signal transduction by p53 class mediator), GO:1901798 (positive regulation of signal transduction by p53 class mediator), GO:1902229 (regulation of intrinsic apoptotic signaling pathway in response to DNA damage), GO:0043516 (regulation of DNA damage response, signal transduction by p53 class mediator), GO:0043516 (regulation of DNA damage response, signal transduction by p53 class mediator), GO:1902253 (regulation of intrinsic apoptotic signaling pathway by p53 class mediator), GO:1902165 (regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator), GO:1902254 (negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005694 (chromosome), GO:0005634 (nucleus)