Protein: Anaphase-promoting complex subunit 2 (Q95TK2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MRVYLTESLRNSLEARILHPGVNTMDILTGYVAAIKAIRHLDSTGVILEMVTAPIKDYLRKRNDTVRRVVTGLTEEGPTDLSEELAKGETIKECKDSGTDEFSNWENWQPDPFGIDASIMQYNSSRKMRSADIISMVVDIYGSKELFMTEYRNLMADRLLAQLDFNSEKEIRNLELLKIRFGESLLHSCEVMLKDVTDSKRINAHIHSDGDRTENQLFDISSLIVSAQFWPSFNKESLQLPEEIENEFKKYTKAYEAYKGNRTLNWRTVTGRVNIEIEIGDRTMEMVVSPILAVIIYHFQTKNEWTIEDLSSITKVPASALRRRLSFWQNHGLISETTPGIFTLLEKESEKSQYEDMSLAEADEEDLESAMASASDQREEELQVFWSYIVGMLTNLDSMPIDRIHQMLKLFASHSGGVEFTQDELKHFLQRKVREHKLIFSGGVYQLAK
InterPro domains: - IPR036317: Cullin homology domain superfamily (homologous_superfamily) [106-351]
- IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [377-447]
- IPR014786: Anaphase-promoting complex subunit 2, C-terminal (domain) [388-447]
- IPR044554: Anaphase-promoting complex subunit 2 (family) [2-448]
- IPR057975: Anaphase-promoting complex subunit 2, TPR repeats (domain) [2-62]
- IPR016158: Cullin homology domain (domain) [132-329]
- IPR001373: Cullin, N-terminal (domain) [142-325]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [377-448]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0050793 (regulation of developmental process), GO:0065008 (regulation of biological quality), GO:0050794 (regulation of cellular process), GO:0023051 (regulation of signaling), GO:0051241 (negative regulation of multicellular organismal process), GO:0051239 (regulation of multicellular organismal process), GO:0045926 (negative regulation of growth), GO:0051093 (negative regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0040008 (regulation of growth), GO:0048522 (positive regulation of cellular process), GO:0051726 (regulation of cell cycle), GO:2000026 (regulation of multicellular organismal development), GO:0051129 (negative regulation of cellular component organization), GO:0010646 (regulation of cell communication), GO:0051961 (negative regulation of nervous system development), GO:0048640 (negative regulation of developmental growth), GO:0050803 (regulation of synapse structure or activity), GO:0099177 (regulation of trans-synaptic signaling), GO:0051128 (regulation of cellular component organization), GO:0048638 (regulation of developmental growth), GO:0044087 (regulation of cellular component biogenesis), GO:1905809 (negative regulation of synapse organization), GO:0051964 (negative regulation of synapse assembly), GO:0050807 (regulation of synapse organization), GO:1901888 (regulation of cell junction assembly), GO:0050804 (modulation of chemical synaptic transmission), GO:0045886 (negative regulation of synaptic assembly at neuromuscular junction), GO:0008582 (regulation of synaptic assembly at neuromuscular junction), GO:0051960 (regulation of nervous system development), GO:1901889 (negative regulation of cell junction assembly), GO:0051963 (regulation of synapse assembly), GO:1904397 (negative regulation of neuromuscular junction development), GO:1904396 (regulation of neuromuscular junction development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:1902494 (catalytic complex), GO:0140513 (nuclear protein-containing complex), GO:0140535 (intracellular protein-containing complex), GO:1990234 (transferase complex), GO:0000151 (ubiquitin ligase complex), GO:0000152 (nuclear ubiquitin ligase complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005680 (anaphase-promoting complex), GO:0043231 (intracellular membrane-bounded organelle), GO:0031461 (cullin-RING ubiquitin ligase complex), GO:0005634 (nucleus)