wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Eukaryotic translation initiation factor 1B, isoform CRA_a (GC20 protein) (cDNA, FLJ92189, Homo sapiens translation factor sui1 homolog (GC20), mRNA) (Q6FG85)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MSTIQNLQSFDPFADATKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLLEVGIVKEEQLKVHGF
InterPro domains: - IPR005874: Eukaryotic translation initiation factor SUI1 (family) [1-113]
- IPR001950: SUI1 domain (domain) [28-102]
- IPR036877: SUI1 domain superfamily (homologous_superfamily) [2-113]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0034248 (regulation of amide metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0051246 (regulation of protein metabolic process), GO:0006446 (regulation of translational initiation), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:0006417 (regulation of translation), GO:0010608 (post-transcriptional regulation of gene expression), GO:2000112 (regulation of cellular macromolecule biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: RIKEN cDNA 1810065E05 gene (Q5NC41)
Organism: Mus musculus (Mouse)
Function: Not known
Sequence: MFWSSVSKSLLAVCVVTEFAVIFVESLSCENSMCTNGLCQPMGTCNTSKSCFSQTQEFKMPELSTSLSVQQKGCSLDECTGLAFSATLGDQRTFRYDQRCCTTDKCNQVDTKPSQVPAKANGVQCLACYMEAGRVCIPTPLKCTGSETKCVAVIGTAVGSSSPLSVVMVGSGCATESACNLNMTVLDFVNIRTFCSSGFPVLPTPSSAPDGLGLRSASISTVPVLISLLLLKVLV
InterPro domains: - IPR016054: Ly-6 antigen/uPA receptor-like (domain) [35-195]
- IPR045860: Snake toxin-like superfamily (homologous_superfamily) [119-198]
- IPR050918: CNF-like Phospholipase A2 Inhibitor (family) [11-232]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:0009617 (response to bacterium), GO:0043207 (response to external biotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Transgelin-2 (Epididymis tissue protein Li 7e) (SM22-alpha homolog) (P37802)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNRGASQAGMTGYGMPRQIL
InterPro domains: - IPR036872: CH domain superfamily (homologous_superfamily) [1-196]
- IPR003096: Smooth muscle protein/calponin (family) [3-190]
- IPR050606: Calponin-like (family) [1-198]
- IPR000557: Calponin repeat (repeat) [174-199]
- IPR001715: Calponin homology domain (domain) [24-136]
Interaction partners: - WD repeat-containing protein 90
- Actin, cytoplasmic 1
- Peptidyl-prolyl cis-trans isomerase A
- Cofilin-1
- Profilin-1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0009888 (tissue development), GO:0030154 (cell differentiation), GO:0061061 (muscle structure development), GO:0048513 (animal organ development), GO:0007517 (muscle organ development), GO:0060429 (epithelium development), GO:0030855 (epithelial cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030054 (cell junction), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0070161 (anchoring junction), GO:0043227 (membrane-bounded organelle), GO:0030055 (cell-substrate junction), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0005925 (focal adhesion), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Rifin (Q8IAS6)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Not known
Sequence: MRIHYINMFLFSLMFNILLNVNKNHYNTTLHTPNTTKIPTTRLLCECELYAPSNYNNDPEMKQVMDNFDRHTQQRFHEYEQRMIKNRKECKEQCEQNIQKLILKEKIQKELKEKFSALQIDISTHDIPTCVCEKSVADKTEKFCLKCGYGLGGALTAWQIFGYTGIYGWANYAALLAHEAGVKAGIKVVIDMFSTYPGLISLPGVDLTKMINGSNFNIPMELVNIVKGLSNGLCKTPNKHLFCAFTNMEKGQSLVSFANSASQSGIMEAASVQGAKVAIIKTTTADFSYNMIVSGITIFVIVLVMVIIYFILRYRRKKKMKKKLQYIKLLKE
InterPro domains: - IPR006373: Variant surface antigen Rifin (family) [1-332]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response), GO:0042783 (evasion of host immune response), GO:0020033 (antigenic variation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0033643 (host cell part), GO:0043657 (host cell), GO:0033644 (host cell membrane), GO:0020002 (host cell plasma membrane)
Protein: Fasciclin-2 (Fasciclin II) (FAS II) (P34082)
Organism: Drosophila melanogaster (Fruit fly)
Function: Neuronal recognition molecule for the MP1 axon pathway, pathway recognition for axons during the development of nerve fascicles.
Subcellular location: [Isoform 1]: Cell membrane {ECO:0000305|PubMed:1913818}; Single-pass type I membrane protein {ECO:0000255}.; SUBCELLULAR LOCATION: [Isoform 2]: Cell membrane {ECO:0000269|PubMed:1913818}; Lipid-anchor, GPI-anchor {ECO:0000305|PubMed:1913818}.
Sequence: MGELPPNSVGVFLALLLCSCSLIELTRAQSPILEIYPKQEVQRKPVGKPLILTCRPTVPEPSLVADLQWKDNRNNTILPKPNGRNQPPMYTETLPGESLALMITSLSVEMGGKYYCTASYANTEILEKGVTIKTYVAITWTNAPENQYPTLGQDYVVMCEVKADPNPTIDWLRNGDPIRTTNDKYVVQTNGLLIRNVQESDEGIYTCRAAVIETGELLERTIRVEVFIQPEIISLPTNLEAVEGKPFAANCTARGKPVPEISWIRDATQLNVATADRFQVNPQTGLVTISSVSQDDYGTYTCLAKNRAGVVDQKTKLNVLVRPQIYELYNVTGARTKEIAITCRAKGRPAPAITFRRWGTQEEYTNGQQDDDPRIILEPNFDEERGESTGTLRISNAERSDDGLYQCIARNKGADAYKTGHITVEFAPDFSHMKELPPVFSWEQRKANLSCLAMGIPNATIEWHWNGRKIKDLYDTNLKIVGTGPRSDLIVHPVTRQYYSGYKCIATNIHGTAEHDMQLKEARVPDFVSEAKPSQLTATTMTFDIRGPSTELGLPILAYSVQYKEALNPDWSTAYNRSWSPDSPYIVEGLRPQTEYSFRFAARNQVGLGNWGVNQQQSTPRRSAPEEPKPLHNPVQHDKEEPVVVSPYSDHFELRWGVPADNGEPIDRYQIKYCPGVKISGTWTELENSCNTVEVMETTSFEMTQLVGNTYYRIELKAHNAIGYSSPASIIMKTTRGIDVIQVAERQVFSSAAIVGIAIGGVLLLLFVVDLLCCITVHMGVMATMCRKAKRSPSEIDDEAKLGSGQLVKEPPPSPLPLPPPVKLGGSPMSTPLDEKEPLRTPTGSIKQNSTIEFDGRFVHSRSGEIIGKNSAV
InterPro domains: - IPR036116: Fibronectin type III superfamily (homologous_superfamily) [524-735]
- IPR051170: Neural and epithelial cell adhesion domain-containing protein (family) [228-666]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [40-527]
- IPR003961: Fibronectin type III (domain) [524-738]
- IPR013098: Immunoglobulin I-set (domain) [143-520]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [33-737]
- IPR007110: Immunoglobulin-like domain (domain) [31-520]
- IPR003598: Immunoglobulin subtype 2 (domain) [45-511]
- IPR003599: Immunoglobulin domain subtype (domain) [39-522]
- IPR009138: Neural cell adhesion (family) [133-329]
Interaction partners: - Fasciclin-1
- Protein elav
- Bruchpilot, isoform J
- Fasciclin-3
- Semaphorin-1A
- Neuroglian
- Microtubule-associated protein futsch
- Glutamate receptor IIA
- Beaten path Ia, isoform B
- Disks large 1 tumor suppressor protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0006950 (response to stress), GO:0009611 (response to wounding), GO:0042060 (wound healing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Lysine demethylase 5B (A0A3B3IT85)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: XRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQLNKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSGDSLRKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTEARTHNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQECSKPQEAFGFEQAARDYTLRTF
InterPro domains: - IPR001606: ARID DNA-binding domain (domain) [34-125]
- IPR011011: Zinc finger, FYVE/PHD-type (homologous_superfamily) [241-299]
- IPR019787: Zinc finger, PHD-finger (domain) [243-293]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [229-316]
- IPR047981: Lysine-specific demethylase 5B, ARID domain (domain) [31-120]
- IPR019786: Zinc finger, PHD-type, conserved site (conserved_site) [246-290]
- IPR036431: ARID DNA-binding domain superfamily (homologous_superfamily) [14-128]
- IPR047978: Lysine-specific demethylase 5B, first PHD-finger (domain) [245-290]
- IPR001965: Zinc finger, PHD-type (domain) [245-291]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0006357 (regulation of transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Small nuclear ribonucleoprotein Sm D3 (Sm-D3) (snRNP core protein D3) (P62320)
Organism: Mus musculus (Mouse)
Function: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome (By similarity). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:P62318}. Nucleus {ECO:0000269|PubMed:19470752}. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes. {ECO:0000250|UniProtKB:P62318}.
Sequence: MSIGVPIKVLHEAEGHIVTCETNTGEVYRGKLIEAEDNMNCQMSNITVTYRDGRVAQLEQVYIRGSKIRFLILPDMLKNAPMLKSMKNKNQGSGAGRGKAAILKAQVAARGRGRGMGRGNIFQKRR
InterPro domains: - IPR027141: Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 (family) [3-114]
- IPR047575: Sm domain (domain) [5-77]
- IPR010920: LSM domain superfamily (homologous_superfamily) [6-118]
- IPR034099: Small nuclear ribonucleoprotein Sm D3 (family) [6-75]
- IPR001163: Sm domain, eukaryotic/archaea-type (domain) [8-73]
Interaction partners: - Small nuclear ribonucleoprotein G
- Small nuclear ribonucleoprotein F
- Small nuclear ribonucleoprotein E
- Small nuclear ribonucleoprotein Sm D2
- Small nuclear ribonucleoprotein Sm D1
- Small nuclear ribonucleoprotein-associated protein B
- U6 snRNA-associated Sm-like protein LSm7
- Pre-mRNA-processing-splicing factor 8
- U1 small nuclear ribonucleoprotein C
- U6 snRNA-associated Sm-like protein LSm3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0019899 (enzyme binding), GO:0003723 (RNA binding), GO:0070034 (telomerase RNA binding), GO:0017069 (snRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0072359 (circulatory system development), GO:0007507 (heart development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1) (P58771)
Organism: Mus musculus (Mouse)
Function: Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P04692}. Note=Associates with F-actin stress fibers. {ECO:0000250|UniProtKB:P04692}.
Sequence: MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
InterPro domains: - IPR000533: Tropomyosin (family) [67-283]
Interaction partners: - Troponin I, cardiac muscle
- Actin, alpha cardiac muscle 1
- Tropomyosin beta chain
- Myosin light chain 1/3, skeletal muscle isoform
- Actin, alpha skeletal muscle
- Troponin T, cardiac muscle
- Myosin regulatory light chain 11
- Troponin T, slow skeletal muscle
- Troponin T, fast skeletal muscle
- Myosin-4
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0005488 (binding), GO:0005200 (structural constituent of cytoskeleton), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0003008 (system process), GO:0003012 (muscle system process), GO:0006936 (muscle contraction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0150034 (distal axon), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0032153 (cell division site), GO:0030427 (site of polarized growth), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0098590 (plasma membrane region), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0032154 (cleavage furrow), GO:0005938 (cell cortex), GO:0030426 (growth cone), GO:0005886 (plasma membrane), GO:0043228 (non-membrane-bounded organelle), GO:0030863 (cortical cytoskeleton), GO:0043005 (neuron projection), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0002102 (podosome), GO:0005856 (cytoskeleton), GO:0030424 (axon), GO:0015629 (actin cytoskeleton)
Protein: Sortilin (Q8IKV8)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Sequence: MKKKLEKQKKLLEYEKGYYSNKVKMRNMLFFKSIGNKNHLFLVFLLFLFFSFSCINFTQCQITKKKVSVSEINFDSAVDDVQWCGNNHMTVLVKTVKGRLYRSSDGGKIWTNITGNLSDKENNKSDPSSNHMNEMTTVDLIMVNSVNKNIVLIIGNQKNHYISEDSGETFRLLNYQNKINFWQFHSTKTHWALVSSWTEACYSNDDNSGECMQTLSLTKDLGRTFQLIDIYVVQFNWGDKESHLEDTIYYTRHKNRNGHQQRFSGWSKDVDFVATHNFGKSVDVLVKQGNKFLISNGYIFVAKLNDVIKQTVNMMVSTDGGKTFNKANLPENIHEKSYTVLDTSEGSIMLHVNHGTSSEKINTGNVYISDASGLNYTLSLPNNIRTSSGECEFDRVLSLDGVYIANFLDVNNEIKDEDLRFQNFKSAIEEDIAPFETNTEKRKKQYNKGKNEDAVRTVISFNKGGEWSYLKAPKVDSRGNKYECGDNCYLHLHGITNYHQYAPFYSIENAVGIIMGTGNVGSHLRYESDEVNTFLSRDGGVTWIEAHKGPYIYEYGDYGGLIVMADDLRKTNQIVFSWNEGQSWFDFELGQFSIDVDNIVAEPNSASVEFLVYGTRNDVGVLYHLDFNALGQPLCKGLWAADSVSSDYETWSPTSGNFNDKCILGRKITYTRRKQTSECFNGKDLKRTVDKKPCECTPEDYECETGFTRKIGSYECKPNDPTLTIEGCTSSSYFYANAYRKVPGDICVNGWVPEKVPVPCPSYAPFNKTAKSILFIIFIMGIVMLIITYICRNPKFKNLFYNYGFDTFENVKYSVIKTKRGNVNNNVFEPEMEFIDAEQDDNEEDVPTLLPYSSDRNRSTNKDFTLARNRTNQNNNITSRNISPSKNYADNIELL
InterPro domains: - IPR031778: Sortilin, N-terminal (domain) [99-599]
- IPR050310: VPS10-related sortilin family receptors (family) [89-765]
- IPR036278: Sialidase superfamily (homologous_superfamily) [99-400]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [57-257]
- IPR006581: VPS10 (domain) [89-765]
- IPR031777: Sortilin, C-terminal (domain) [602-758]
Interaction partners: - Vacuolar protein sorting-associated protein 35
- Calponin homology domain-containing protein, putative
- Proteasome subunit beta
- Proteasome subunit alpha type
- Proteasome subunit alpha type-1, putative
- Proteasome subunit alpha type
- Proteasome subunit beta
- Vacuolar protein sorting-associated protein 26
- Phosphoinositide phosphatase SAC1
- SDE2-like domain-containing protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0046907 (intracellular transport), GO:0045184 (establishment of protein localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0006886 (intracellular protein transport), GO:0016192 (vesicle-mediated transport), GO:0071705 (nitrogen compound transport), GO:0008104 (protein localization), GO:0015031 (protein transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)
Protein: Transducin/WD40 repeat-like superfamily protein (F4K0D3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MDLICNSYANDSDDEPEPVTNERLTSKIAAAPSIPSKRPYPVPEERQYKPPRRPYPPHGSYSESQTSSSFSIPVPVPVPVPGRYVSKRERSLLASLSTIPTPDQSSDLSQKPYSSPTVLGSISDSDVPRHVLSSVRHRPKGSSLQTEMPSRMSISLTGHTKAVTAIDWSTSHVHLLASAGLDGAVYVWNVWSNDKKKVRAFLHHNAPVKDVKWSKQGLSLLSCGYDCTSRLFDVERGVETQSFKEDEVVGVVKFHPDNCNVFLSGGSKGSLRLWDIRANKFVHEYVRDLGPILDVEFIAGGKQFISSSDVSGRNISENAVIVWDISREVPLSNQVYVEAYTCPCIKRHPQDPVFIAQSHGNYTAIFSTNPPFKLNKYKRFEGHWVAGFPIKCNFSPDGETLASGSSDGSVYMYDYKSTALIKKLKAYEQPCVNVSYHPVLPNVVAACSWNGQVSVFE
InterPro domains: - IPR001680: WD40 repeat (repeat) [149-457]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [148-456]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [131-457]
- IPR053053: WD repeat-containing protein (family) [3-457]
- IPR019775: WD40 repeat, conserved site (conserved_site) [176-190]
Interaction partners: - Pre-mRNA-splicing factor SYF2
- Pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH7
- At2g20330/F11A3.12
- CwfJ-like family protein
- At3g05070
- Protein pleiotropic regulatory locus 1
- Protein pleiotropic regulator PRL2
- Peptidyl-prolyl cis-trans isomerase CYP18-2
- Pre-mRNA-processing factor 19 homolog 2
- Peptidyl-prolyl cis-trans isomerase CYP57
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0008380 (RNA splicing), GO:0006397 (mRNA processing), GO:0016071 (mRNA metabolic process), GO:0000398 (mRNA splicing, via spliceosome), GO:0000375 (RNA splicing, via transesterification reactions), GO:0000380 (alternative mRNA splicing, via spliceosome), GO:0000377 (RNA splicing, via transesterification reactions with bulged adenosine as nucleophile)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)