Protein: Down syndrome cell adhesion molecule 1, isoform AX (Q0E9L8)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MNMPNERLKWLMLFAAVALIACGSQTLAANPPDADQKGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKLVFPPFRAEDYRQEVHAQVYACLARNQFGSIISRDVHVRAVVHQFYQTRVIDEFVLRGNSATLKCLVPSFVADFIDVEGWIDEEGVEILRPLPDDSVDGKYLVLPSGELHIREVGPEDGYKSYQCRTKHRLTGETRLSATKGRLVITEPIGARAPTFSTDSNSFSYTRSVGQSFALLCQAQAYPVPIMRWYKFIEGTTRKQAVVLNDRVKQVSGTLIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNPIKTVSWMKDGKAIGHSEPVLRIESVKKEDKGMYQCFVRNDQESAEASAELKLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANNDRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNVYGLPYIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRALPINRKQKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSARGSLEVQVMVPPKITPFDFGDAPTNVEDSVSVMCLISNGDLPIDIEWFFNDYGISSYSGINVVKGGKRNSMLSIDSVQARHAGKYSCRAKNHAAAVNYTTELIVNVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGDTPGEYKDLKKSDNIRVEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNNMRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDRVIVPGHTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETINFITEEGKEHNLELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYDETKRHYKKTASSDTVLHGLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEAPTDVKALVMGNAAILVSWRPPAQPNGIITQYTVYSKAEGAETETKTQKVPHYQMSFEATELEKNKPYEFWVTASTTIGEGQQSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIKGVEFSANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPPQSPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEFGEWETSEVSVDSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPEKPRFIEVSSNSVSLHFKAWKDGGCPMSHFVVESKKRDQIEWNQISNNVKPDNNYVVLDLEPATWYNLRITAHNSAGFTVAEYDFATLTVTGGTIAPSRDLPELSAEDTIRIILSNLNLVVPVVAALLVIIIAIIVICILRSKGNHHKDDVVYNQTMGPGATLDKRRPDLRDELGYIAPPNRKLPPVPGSNYNTCDRIKRGRGGLRSNHSTWDPRRNPNLYEELKAPPVPMHGNHYGHAHGNAECHYRHPGMEDEICPYATFHLLGFREEMDPTKAMNFQTFPHQNGHAGPVPGHAGTMLPPGHPGHVHSRSGSQSMPRANRYQRKNSQGGQSSIYTPAPEYDDPANCAEEDQYRRYTRVNSQGGSLYSGPGPEYDDPANCAPEEDQYGSQYGGPYGQPYDHYGSRGSMGRRSIGSARNPGNGSPEPPPPPPRNHDMSNSSFNDSKESNEISEAECDRDHGPRGNYGAVKRSPQPKDQRTTEEMRKLIERNETGPKQLQLQQANGAGFTAYDTMAV
InterPro domains: - IPR036116: Fibronectin type III superfamily (homologous_superfamily) [912-1583]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [38-1408]
- IPR003961: Fibronectin type III (domain) [914-1597]
- IPR013098: Immunoglobulin I-set (domain) [260-1402]
- IPR007110: Immunoglobulin-like domain (domain) [39-1397]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [33-1592]
- IPR056754: DSCAM/DSCAML, C-terminal domain (domain) [1512-1600]
- IPR003598: Immunoglobulin subtype 2 (domain) [52-1392]
- IPR003599: Immunoglobulin domain subtype (domain) [46-1403]
- IPR021012: Cell adhesion molecule Dscam1, C-terminal (domain) [1871-1989]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0005488 (binding), GO:0003823 (antigen binding), GO:0038023 (signaling receptor activity), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0004888 (transmembrane signaling receptor activity), GO:0046983 (protein dimerization activity), GO:0042803 (protein homodimerization activity), GO:0008046 (axon guidance receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0051179 (localization), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0040007 (growth), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0048869 (cellular developmental process), GO:0009628 (response to abiotic stimulus), GO:0048856 (anatomical structure development), GO:0048589 (developmental growth), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0042221 (response to chemical), GO:0042330 (taxis), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0003008 (system process), GO:0050793 (regulation of developmental process), GO:0016049 (cell growth), GO:0009607 (response to biotic stimulus), GO:0050794 (regulation of cellular process), GO:0008037 (cell recognition), GO:0051606 (detection of stimulus), GO:0051707 (response to other organism), GO:0009581 (detection of external stimulus), GO:0032989 (cellular component morphogenesis), GO:0021551 (central nervous system morphogenesis), GO:0050773 (regulation of dendrite development), GO:0008038 (neuron recognition), GO:0009593 (detection of chemical stimulus), GO:0043207 (response to external biotic stimulus), GO:0048468 (cell development), GO:0060560 (developmental growth involved in morphogenesis), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009582 (detection of abiotic stimulus), GO:0009595 (detection of biotic stimulus), GO:0016319 (mushroom body development), GO:0050906 (detection of stimulus involved in sensory perception), GO:0010033 (response to organic substance), GO:0000902 (cell morphogenesis), GO:0048588 (developmental cell growth), GO:0060322 (head development), GO:0009617 (response to bacterium), GO:0006810 (transport), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0016043 (cellular component organization), GO:0050877 (nervous system process), GO:0009612 (response to mechanical stimulus), GO:0051128 (regulation of cellular component organization), GO:0006935 (chemotaxis), GO:0007419 (ventral cord development), GO:0030030 (cell projection organization), GO:0007413 (axonal fasciculation), GO:0031344 (regulation of cell projection organization), GO:0097485 (neuron projection guidance), GO:0032990 (cell part morphogenesis), GO:0070593 (dendrite self-avoidance), GO:0002237 (response to molecule of bacterial origin), GO:0048814 (regulation of dendrite morphogenesis), GO:0050982 (detection of mechanical stimulus), GO:0007600 (sensory perception), GO:0048666 (neuron development), GO:0050974 (detection of mechanical stimulus involved in sensory perception), GO:0007420 (brain development), GO:0022008 (neurogenesis), GO:0050770 (regulation of axonogenesis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0032490 (detection of molecule of bacterial origin), GO:0007399 (nervous system development), GO:0007422 (peripheral nervous system development), GO:0098581 (detection of external biotic stimulus), GO:0007417 (central nervous system development), GO:0016192 (vesicle-mediated transport), GO:0048858 (cell projection morphogenesis), GO:1990138 (neuron projection extension), GO:0030182 (neuron differentiation), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0006909 (phagocytosis), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:1902284 (neuron projection extension involved in neuron projection guidance), GO:0050976 (detection of mechanical stimulus involved in sensory perception of touch), GO:0007411 (axon guidance), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0048675 (axon extension), GO:0050954 (sensory perception of mechanical stimulus), GO:0050975 (sensory perception of touch), GO:0048812 (neuron projection morphogenesis), GO:0061564 (axon development), GO:0106030 (neuron projection fasciculation), GO:0007409 (axonogenesis), GO:0010975 (regulation of neuron projection development), GO:0048846 (axon extension involved in axon guidance)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0044297 (cell body), GO:0036477 (somatodendritic compartment), GO:0042995 (cell projection), GO:0097447 (dendritic tree), GO:0043025 (neuronal cell body), GO:0120025 (plasma membrane bounded cell projection), GO:0043005 (neuron projection), GO:0030425 (dendrite), GO:0030424 (axon)