wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Signal recognition particle receptor alpha subunit, putative (Q383U0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004397}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004397}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004397}.
Sequence: MIDTLSIVSNGGIVLWERSSDVSRKCSIINQVIQEFLLEDRAGMHETVIGDYKVHWMLENDAHFFVVAIHPKFVSYPQMCAFLRTIARCFVKKYGRVRDNVLVEYDFSAEYAETLSMLDAGVPGVDALGGGDQISNGDTEGEEEDEDLLEDAADREPQGEGECSAAGAASGAYQGPDTFVTKSGHVIGRKGKKLAGSKSTTATSQKRSKQVKRATRWDEPSADSAVEEQRGQGTRPTEEELEVQTALQRAAFIKRLPNGSVAPVREKEWEGQQRGLLANWLRSYVGRRELDSQDFNNVIPGLREKLITKNVAVEVAEHVCKSVEASLTGKVLGTFESLHQCIEAAMISALRRILQPKHEINILRAVASSRGRNKPYSIVLCGVNGVGKSTTLAKITYWLQQNGHTVMIAAGDTFRHGAVEQLEVHGRCLGVDVFQMGYGTDPSAVAAAAISRATRDGCDVVMIDTAGRMQDHESRMRALAKLIHDNQPDLVLFVGEALVGNTGVDQLRRFNQCLVDFVPVGSVPRGIDGIVLTKFDTIDDKVGAAVSMVYELGQPIVFVGAGQTYQDLKVMEPDVVVSALMA
InterPro domains: - IPR007222: Signal recognition particle receptor, alpha subunit, N-terminal (domain) [27-223]
- IPR000897: Signal recognition particle, SRP54 subunit, GTPase domain (domain) [375-582]
- IPR042101: Signal recognition particle SRP54, N-terminal domain superfamily (homologous_superfamily) [253-356]
- IPR003593: AAA+ ATPase domain (domain) [374-519]
- IPR036225: SRP/SRP receptor, N-terminal (homologous_superfamily) [277-356]
- IPR011012: Longin-like domain superfamily (homologous_superfamily) [1-120]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [359-582]
- IPR013822: Signal recognition particle SRP54, helical bundle (domain) [278-343]
Interaction partners: - Signal recognition particle 54 kDa protein
- Signal recognition particle receptor subunit beta
- Signal recognition particle subunit SRP72
- Signal recognition particle subunit SRP68
- 60S ribosomal protein L5, putative
- SRP19 protein
- Large ribosomal subunit protein uL5
- 60S ribosomal protein L17, putative
- 60S ribosomal protein L35, putative
- Pretranslocation protein, alpha subunit, putative
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Glutaredoxin 5 (D4ADD7)
Organism: Rattus norvegicus (Rat)
Function: Not known
Sequence: MRLPGKAHRYGVSDMIGGIEPVLSNHETHPRAYPMRTSSGPAGHQGLCKPSGGRRSGDQRAGMSASLSRAAAALLRWGRGAGGGVLPRAGVRAASSGGQAEQLDALVKKDKVVVFLKGTPEQPQCGFSNAVVQILRLHGVRDYAAYNVLEDPELRQGIKDYSNWPTIPQVYLNGEFVGGCDILLQMHQNGDLVEELKKLGIRSALIDEKDQDSK
InterPro domains: - IPR033658: Glutaredoxin, PICOT-like (domain) [103-193]
- IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [101-201]
- IPR002109: Glutaredoxin (domain) [112-177]
- IPR004480: Monothiol glutaredoxin-related (family) [64-207]
Interaction partners: - BolA-like protein 1
- Iron-sulfur cluster assembly 1 homolog, mitochondrial
- BolA-like protein 2
- BolA-like protein 3
- Iron-sulfur cluster assembly 2 homolog, mitochondrial
- Iron-sulfur clusters transporter ABCB7, mitochondrial
- Iron-sulfur cluster assembly enzyme ISCU
- Glutaredoxin-3
- Mitochondrial glycine transporter
- Iron-sulfur cluster co-chaperone protein HscB
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0051020 (GTPase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:1901698 (response to nitrogen compound), GO:0010033 (response to organic substance), GO:0010243 (response to organonitrogen compound), GO:0014075 (response to amine), GO:0001975 (response to amphetamine)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0043233 (organelle lumen), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043005 (neuron projection), GO:0043231 (intracellular membrane-bounded organelle), GO:0005759 (mitochondrial matrix), GO:0070013 (intracellular organelle lumen)
Protein: GM14561p (Q95S24)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MLLKGLPGFVALWVVLQLAGADSPEEEQGVRYANRCEACKILATELEARLGETGKSHDVIEIGYSVDDVKPKKRTEYRRSELRLLESLENVCERVLEYNLHKERSDSTRFAKGMSQTFQTLHGLVDKGVKVDLGIPYELWDKPPVEVTQMKTQCENLLEEYEETISDWYFKHQDEKSLKKHLCEDHVLKKKAERECLKEQLAPPEAKKAKREKAKGDKEEL
InterPro domains: - IPR021852: Domain of unknown function DUF3456 (domain) [35-189]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0051087 (chaperone binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0006457 (protein folding), GO:0061077 (chaperone-mediated protein folding)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0012505 (endomembrane system)
Protein: N-acyl-aliphatic-L-amino acid amidohydrolase (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase) (V9HWA0)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Sequence: MTSKGPEEEHPSVTLFRQYLRIRTVQPKPDYGAAVAFFEETARQLGLGCQKVEVAPGYVVTVLTWPGTNPTLSSILLNSHTDVVPVFKEHWSHDPFEAFKDSEGYIYARGAQDMKCVSIQYLEAVRRLKVEGHRFPRTIHMTFVPDEEVGGHQGMELFVQRPEFHALRAGFALDEGIANPTDAFTVFYSERSPWWVRVTSTGRPGHASRFMEDTAAEKLHKVVNSILAFREKEWQRLQSNPHLKEGSVTSVNLTKLEGGVAYNVIPATMSASFDFRVAPDVDFKAFEEQLQSWCQAAGEGVTLEFAQKWMHPQVTPTDDSNPWWAAFSRVCKDMNLTLEPEIMPAATDNRYIRAVGVPALGFSPMNRTPVLLHDHDERLHEAVFLRGVDIYTRLLPALASVPALPSDS
InterPro domains: - IPR002933: Peptidase M20 (family) [76-395]
- IPR052083: Aminoacylase-1 peptidase M20A (family) [5-402]
- IPR011650: Peptidase M20, dimerisation domain (domain) [189-298]
- IPR010159: N-acyl-L-amino-acid amidohydrolase (family) [1-401]
- IPR001261: ArgE/DapE/ACY1/CPG2/YscS, conserved site (conserved_site) [75-150]
- IPR036264: Bacterial exopeptidase dimerisation domain (homologous_superfamily) [194-307]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0016811 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0080090 (regulation of primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0006508 (proteolysis), GO:0051246 (regulation of protein metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005615 (extracellular space), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0005576 (extracellular region), GO:0070062 (extracellular exosome), GO:0043227 (membrane-bounded organelle), GO:0043230 (extracellular organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:1903561 (extracellular vesicle)
Protein: Rhino (Q49BK5)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MSRNHQRPNLGLVDAPPNDHVEEYVVEKILGKRFVNGRPQVLVKWSGFPNENNTWEPLENVGNCMKLVSDFESEVFRLHRKAAAKSVGKSKSSPSSSGPLITENGTSSSKKTQQHSKSVQAKNTAGMSKMDQKKGKNIKKTAGKIKDIENYPKTQMPITSQVSTDSTEVFDGSPSATTTNMIKSPRIQSLFSDLNLIEPTKDKDVGDTSLKTHPKSRRPIEFPQREDAPLSSKHVSPMLIRKESQPLQSSCTDDSDLGESSSSMSLPTVSSTSSEKSIKVTKSEPKTLGQIKFSSRSSDGGHAASSLGAPKEGDIGLDLSGSDSMDSEVESMRRCPRRKRKKTYPNWKFPEITKPFGVNRGLDLDEILHCYQMNDDLFMFVTWKGCSSIDAVHINDIKEAYPLQIIKYFESLRIIVPK
InterPro domains: - IPR000953: Chromo/chromo shadow domain (domain) [23-76]
- IPR023780: Chromo domain (domain) [24-73]
- IPR051219: Heterochromatin-associated chromo domain-containing protein (family) [19-408]
- IPR016197: Chromo-like domain superfamily (homologous_superfamily) [18-416]
- IPR049558: Rhino, chromodomain (domain) [23-73]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0007389 (pattern specification process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0048609 (multicellular organismal reproductive process), GO:0007276 (gamete generation), GO:0030707 (follicle cell of egg chamber development), GO:0007281 (germ cell development), GO:0030703 (eggshell formation), GO:0009888 (tissue development), GO:0003002 (regionalization), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0030381 (chorion-containing eggshell pattern formation), GO:0002064 (epithelial cell development), GO:0007292 (female gamete generation), GO:0048477 (oogenesis), GO:0007304 (chorion-containing eggshell formation), GO:0060429 (epithelium development), GO:0030855 (epithelial cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Protein BIG GRAIN 1-like D (Q9LYH0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in auxin transport. Regulator of the auxin signaling pathway.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:Q10R09}.
Sequence: MHKSKRNPSFSSTLLDEIYNSIDPKTQKTQPYVGSVNTTTKKQSIVTRSVPDRKIHRDRFFGSVSSSSDSNSSIFSSSDTELTHGKKTTSSRPLCFGPSKTKPRKTEDKTLFHQNRATRVYDDYDYASDVPKFNRHDENWENTRNRRSVKSSGNQKKPKTPASPGGRIVNFLNSLFSNNSKQSNAVKSYPRKTSYDDSAYVRKTSNDYHSSTTTCSSASSFSRSCMNKGYEKSSGRIKRSVRFSPVNVIVPESFTSKEEDYFSNGNARKSVKKNVEDGGRRSVEEIAREFLRDYHKNHENSLVKTNGFEDYEDDDEDDDDDDVASDSSSDLFELDLVGNHHHHNVYGDELPVYETTFAGLIL
InterPro domains: - IPR039621: Protein BIG GRAIN 1-like (family) [3-356]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0050793 (regulation of developmental process), GO:0065008 (regulation of biological quality), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0051234 (establishment of localization), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0007154 (cell communication), GO:0009991 (response to extracellular stimulus), GO:0104004 (cellular response to environmental stimulus), GO:2000280 (regulation of root development), GO:0042594 (response to starvation), GO:0033554 (cellular response to stress), GO:0071214 (cellular response to abiotic stimulus), GO:0006810 (transport), GO:0009629 (response to gravity), GO:0006970 (response to osmotic stress), GO:0071495 (cellular response to endogenous stimulus), GO:1901700 (response to oxygen-containing compound), GO:0031668 (cellular response to extracellular stimulus), GO:0071496 (cellular response to external stimulus), GO:0010033 (response to organic substance), GO:0009606 (tropism), GO:0009725 (response to hormone), GO:0009630 (gravitropism), GO:0097305 (response to alcohol), GO:0032870 (cellular response to hormone stimulus), GO:0033993 (response to lipid), GO:0009267 (cellular response to starvation), GO:0031667 (response to nutrient levels), GO:0071470 (cellular response to osmotic stress), GO:0009737 (response to abscisic acid), GO:0031669 (cellular response to nutrient levels), GO:0015698 (inorganic anion transport), GO:0006972 (hyperosmotic response), GO:0009958 (positive gravitropism), GO:0060918 (auxin transport), GO:0043562 (cellular response to nitrogen levels), GO:0042538 (hyperosmotic salinity response), GO:0071474 (cellular hyperosmotic response), GO:0071396 (cellular response to lipid), GO:0009926 (auxin polar transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: TBC1 domain family member 25 (Q3MII6)
Organism: Homo sapiens (Human)
Function: Acts as a GTPase-activating protein specific for RAB33B. Involved in the regulation of autophagosome maturation, the process in which autophagosomes fuse with endosomes and lysosomes.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21383079}. Cytoplasmic vesicle, autophagosome {ECO:0000269|PubMed:21383079}. Note=It is dispersed in the cytoplasm under nutrient-rich conditions. Localizes at autophagosomes under cell starving conditions.
Sequence: MATASGASDLSGSGAPPPGVGAQAAAAAEEEEREVVRVRVKKCESFLPPEFRSFAVDPQITSLDVLQHILIRAFDLSGKKNFGISYLGRDRLGQEVYLSLLSDWDLSTAFATASKPYLQLRVDIRPSEDSPLLEDWDIISPKDVIGSDVLLAEKRSSLTTAALPFTQSILTQVGRTLSKVQQVLSWSYGEDVKPFKPPLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYEQLKSEWAQRANPEDLEFIRSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLPPDPPEHEVELVGPPSQVADAGFGGHRGWPVRQRHMLRPAGGGGSTFEDAVDHLATASQGPGGGGRLLRQASLDGLQQLRDNMGSRRDPLVQLPHPAALISSKSLSEPLLNSPDPLLSSFSHPDSPSSSSPPSTQEASPTGDMAVGSPLMQEVGSPKDPGKSLPPVPPMGLPPPQEFGRGNPFMLFLCLAILLEHRDHIMRNGLDYNELAMHFDRLVRKHHLGRVLRRARALFADYLQSEVWDSEEGAEATAAS
InterPro domains: - IPR035969: Rab-GAP-TBC domain superfamily (homologous_superfamily) [204-670]
- IPR000195: Rab-GAP-TBC domain (domain) [225-457]
Interaction partners: - Gamma-aminobutyric acid receptor-associated protein-like 2
- GABA type A receptor associated protein like 1
- Ras-related protein Rab-33B
- Gamma-aminobutyric acid receptor-associated protein
- Ras-related protein Rab-33A
- Microtubule-associated protein 1 light chain 3 beta
- Transcription factor E3
- Ubiquitin carboxyl-terminal hydrolase 6
- Cell division cycle protein 16 homolog
- ETS domain-containing protein Elk-1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0008047 (enzyme activator activity), GO:0060589 (nucleoside-triphosphatase regulator activity), GO:0030695 (GTPase regulator activity), GO:0005096 (GTPase activator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport), GO:0048193 (Golgi vesicle transport), GO:0006892 (post-Golgi vesicle-mediated transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0005769 (early endosome), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)
Protein: histidine kinase (EC 2.7.13.3) (Q1D948)
Organism: Myxococcus xanthus (strain DK1622)
Function: Not known
Sequence: MTVPAELASAPSAPDTPELSVRMLRSVMLYYERTYGRDRLVRVWQREELPLTLAYVETLTNFVSVGFTERLFDVLDKDSGDPDFMTKAGRSIASPEAVGFLYYMMKALATPRSVYERALELDHTYNRVGGFHIDTLTDSRVQVRYVSRIRERDRNFCRARQGNLSAFPAIWNLPLAEVKELRCQVDGADCCEYDIRWQSLPPLAWRYIVGGMAGMVAGLVSGTLNLAPPVFAVSSLGMVGVAAGAWLDTRAALLRKDEKLSEQHQGLQTSLEDLQRRNDEIFAANKALEDRVAERTQELSEANTKLEASLARQQELDRLKSEFFDNVSHELRTPLTLILLTLEALAKEAESLPPELPPLVTNMERSAQRLLRLINNLLDLAQLESGKARLRYQPLELFGFLSTVVPPFHTMAERQGVTLRLEGATVTPVHVDHERIEIVFQNLLGNALKFTQKGGVTVRVREDDSEVHVEVEDSGQGIAPQDIPVIFDRFSQADNSGTRRFGGSGIGLALVKETLELHAGGISVTSELGQGSVFHVRLPKGTAHIREDLRERRQAVMPVRRERRISGAFPSLEPTGTDVLGASPPPARDHAGPGPESPRIMVVEDDPEIRSFLARLLAQHYRVMEAINGDDGRQRALRERPDLILSDVMMPVMSGLQMLTALRNDPQTVDIPVILLTARQEVTAKVEGLGTGANDYLGKPFSPNELLARIETQLRLREAAVRAAENERLAAIGLLTSGFAHEVRNPLNGLMNALLPLKDMLTGGSADVELSKAMLEVVEECGQRIRHLAESLLSFTRTSESPVVLSLDSSLDSTLSVLAWKVPPGVKVERAYHCSEPIRGNPGALNQVWLNLLDNALRAVGDKGRVRISTANTAEEAIVTIGDDGVGIRPEDMERLFQPFFSTRAAGEGTGLGLALSRRIIIQHGGSIALSSVPGEGTQVEVRLPLRPVAPRVTGGLPDLASEPRVGRLG
InterPro domains: - IPR036890: Histidine kinase/HSP90-like ATPase superfamily (homologous_superfamily) [375-950]
- IPR003594: Histidine kinase/HSP90-like ATPase domain (domain) [431-948]
- IPR001789: Signal transduction response regulator, receiver domain (domain) [598-714]
- IPR005467: Histidine kinase domain (domain) [326-948]
- IPR036097: Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily (homologous_superfamily) [306-799]
- IPR011006: CheY-like superfamily (homologous_superfamily) [593-721]
- IPR004358: Signal transduction histidine kinase-related protein, C-terminal (domain) [467-945]
- IPR003661: Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (domain) [319-801]
- IPR024096: NO signalling/Golgi transport ligand-binding domain superfamily (homologous_superfamily) [130-197]
Interaction partners: - histidine kinase
- Response regulator FrzZ
- Conserved domain protein
- Response regulator
- PilZ domain-containing protein
- histidine kinase
- Sensory/regulatory protein RpfC
- histidine kinase
- Response regulator
- histidine kinase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0044403 (biological process involved in symbiotic interaction), GO:0050794 (regulation of cellular process), GO:1900190 (regulation of single-species biofilm formation), GO:0051701 (biological process involved in interaction with host), GO:1900231 (regulation of single-species biofilm formation on inanimate substrate), GO:0044406 (adhesion of symbiont to host)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Centromere protein F (E9PY14)
Organism: Mus musculus (Mouse)
Function: Not known
Sequence: MSWALEEWKEGLPSRALQKIQELEGQLEKLKKEKQQRQFQLDSLEAALQKQKQKVEDGKTEGADLKRENQRLMEICEHLEKSRQKLSHELQVKESQVNLQESQLSSCKKQIEKLEQELKRCKSEFERSQQVAQSADVSLNPCSTPQKLFATPLTPSSTYEDLKEKYNKEVEERKRLEEEVKALHAKKVSLPVSQATMNHRDIARHQASSSVFPWQQENTPSRLSSDALKTPLRRDGSAAHFLGEEVSPNKSSMKTGRGDCSSLPDLKSKMTELELRLQGQEKEMRSQVNKCQDLQLQLEKTKVELIEKERILNKTRDEVVRSTAQYDQAAAKCTTLEQKLKTLTEELSCHRQNAESAKRSLEQRIKEKEKELQEELSRQHQSFQALDSEYTQMKTRLTQELQQVKHLHSTLQLELEKVTSVKQQLERNLEEIRLKLSRAEQALQASQVAENELRRSSEEMKKENSLIRSQSEQRTREVCHLEEELGKVKVSLSKSQNFAEEMKAKNTSQEIMLRDLQEKLNQQENSLTLEKLKLALADLERQRNCSQDLLKKREHHIDQLNNKLNKIEKEFETLLSALELKKKECEELKEEKNQISFWKIDSEKLINQIESEKEILLGKINHLETSLKTQQVSPDSNERIRTLEMERENFTVEIKNLQSMLDSKMVEIKTQKQAYLELQQKSESSDQKHQKEIENMCLKANKLTGQVESLECKLQLLSSEVVTKDQQYQDLRMEYETLRDLLKSRGSSLVTNEDNQRSSEDNQRSSEDNQRGSLAFEQQPAVSDSFANVMGRKGSINSERSDCSVDGGRSPEHIAILQNRVTSLESSLESQNQMNSDLQMRCEELLQIKGEVEENLSKAEQIHQNFVAETNQCISKLQEDAAVHQNIVAETLATLESKEKELQLLKEKLEAQQTEVQKLNKNNCLLEGTLKELQLLSDTLSSEKKEMNSIIS
InterPro domains: - IPR018463: Centromere protein Cenp-F, N-terminal (domain) [1-288]
- IPR043513: Centromere protein Cenp-F (family) [1-952]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050793 (regulation of developmental process), GO:0048634 (regulation of muscle organ development), GO:1901861 (regulation of muscle tissue development), GO:0016202 (regulation of striated muscle tissue development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0005930 (axoneme), GO:0140535 (intracellular protein-containing complex), GO:0005737 (cytoplasm), GO:0036064 (ciliary basal body), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0099568 (cytoplasmic region), GO:0043228 (non-membrane-bounded organelle), GO:0005813 (centrosome), GO:0097539 (ciliary transition fiber), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005929 (cilium), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0032838 (plasma membrane bounded cell projection cytoplasm), GO:0005634 (nucleus), GO:0005856 (cytoskeleton), GO:0097014 (ciliary plasm), GO:0015630 (microtubule cytoskeleton), GO:0045120 (pronucleus)