Protein: Tyrosine-protein phosphatase non-receptor type (EC 3.1.3.48) (A0A8I5YBL2)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245, ECO:0000256|PIRNR:PIRNR000927}.
Sequence: MLRCGLHTTSSGTGYSAAVMTSRLRALGGRINNIRTSELPKEKTRSEVTCSIRFLDGLVQTFKVNKQDLGQSLLDMAYGHLGVTEKEYFGLQHGDDPVDSPRWLEASKPLRKQLKGGLPCILHFRVRYFIPDPNTLQQEQTRHLYFLQLKMDVCEGRLTCPLNSAVVLASYAVQSHIGDFNSSIHHPGYLADSQFIPDQNDDFLSKVESLHEQHSGLKQSEAESCYINIARTLDFYGVELHGGRDLHNLDLMIGIASAGIAVYRKYICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHSFFQAKKLLPQEKNVLSQYWTLGSRNPKKSVNNQYCKKVIGGMVWNPVMRRSLSVERLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSLSPKDSDSEVSQNHSPHRGSLSENNPAQSCLTQKSSSSVSPCSNAPGSFSPDGVDQQFLEDYHKVTKGGSIEEASQYYCDKNDDGDGYLVLIRITPDKEGRFGFNLKGGVDQKMPLVVSRINPESPADTCMPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRESHSRELALVIRRKAVRSLAEIRSEDELSQLFPEAMFPACPEGGDSLEGSMELLKKGLESGTVLIQFEQLYRKKPGLAVTFAKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHTCAQFWQVVWDQKLSLVVMLTTLTERGRTKCHQYWPDPPDIMDHGIFHIQCQAEDCTIAYVSREMLVTNTETGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVKYVRSLRVGGEPALVHCSAGIGRTGVLVTMETAMCLIERNLPVYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRVYEEGLVQTLDPS
InterPro domains: - IPR036034: PDZ superfamily (homologous_superfamily) [517-616]
- IPR018979: FERM, N-terminal (domain) [52-115]
- IPR014352: FERM/acyl-CoA-binding protein superfamily (homologous_superfamily) [128-235]
- IPR019749: Band 4.1 domain (domain) [44-241]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [236-330]
- IPR035963: FERM superfamily, second domain (homologous_superfamily) [131-236]
- IPR012151: Protein-tyrosine phosphatase, non-receptor type-3, -4 (family) [20-932]
- IPR001478: PDZ domain (domain) [529-617]
- IPR041783: PTPN3/4, FERM domain C-lobe (domain) [235-328]
- IPR000387: Tyrosine-specific protein phosphatases domain (domain) [838-911]
- IPR016130: Protein-tyrosine phosphatase, active site (active_site) [859-869]
- IPR029021: Protein-tyrosine phosphatase-like (homologous_superfamily) [648-930]
- IPR019747: FERM conserved site (conserved_site) [211-240]
- IPR029071: Ubiquitin-like domain superfamily (homologous_superfamily) [46-131]
- IPR000299: FERM domain (domain) [48-331]
- IPR018980: FERM, C-terminal PH-like domain (domain) [245-335]
- IPR003595: Protein-tyrosine phosphatase, catalytic (domain) [819-919]
- IPR000242: Tyrosine-specific protein phosphatase, PTPase domain (domain) [664-922]
- IPR019748: FERM central domain (domain) [132-241]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0004721 (phosphoprotein phosphatase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0004725 (protein tyrosine phosphatase activity), GO:0016791 (phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0031099 (regeneration), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048732 (gland development), GO:0031100 (animal organ regeneration), GO:0061008 (hepaticobiliary system development), GO:0001889 (liver development), GO:0097421 (liver regeneration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)