Protein: ubiquitinyl hydrolase 1 (D6RBV3)
Organism: Homo sapiens (Human)
Sequence: MRVKDPTKALPEKAKRSKRPTVPHDEDSSDDIAVGLTCQHVSHAISVNHVKRAIAENLWSVCSECLKERRFYDGQLVLTSDIWLCLKCGFQGCGKNSESQHSLKHFKSSRTEPHCIIINLSTWIIWCYECDEKLSTHCNKKVLAQIVDFLQKHASKTQTSAFSRIMKLCEEKCETDEIQKGGKCRNLSVRGITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPSSDSQLDPLVVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKWVHLHLI
InterPro domains: - IPR028889: Ubiquitin specific protease UPS, catalytic domain (domain) [190-289]
- IPR018200: Ubiquitin specific protease, conserved site (conserved_site) [191-206]
- IPR050164: Ubiquitin carboxyl-terminal hydrolases (family) [59-281]
- IPR001607: Zinc finger, UBP-type (domain) [36-153]
- IPR038765: Papain-like cysteine peptidase superfamily (homologous_superfamily) [189-286]
- IPR001394: Peptidase C19, ubiquitin carboxyl-terminal hydrolase (domain) [190-279]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [34-155]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0080134 (regulation of response to stress), GO:0019538 (protein metabolic process), GO:0080135 (regulation of cellular response to stress), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0006508 (proteolysis), GO:0051052 (regulation of DNA metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:2001020 (regulation of response to DNA damage stimulus), GO:0000018 (regulation of DNA recombination), GO:0006282 (regulation of DNA repair), GO:0070646 (protein modification by small protein removal), GO:0070647 (protein modification by small protein conjugation or removal), GO:0016570 (histone modification), GO:0016579 (protein deubiquitination), GO:0010569 (regulation of double-strand break repair via homologous recombination), GO:0016578 (histone deubiquitination), GO:2000779 (regulation of double-strand break repair), GO:2001032 (regulation of double-strand break repair via nonhomologous end joining)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)