Protein: Rhea, isoform I (M9PF06)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MSTLSLRIQLEGGRVTKTIQFQPNTTVFDACKVIRDKFAEAVQGQPSEYGLFISDEQNQQGVWLEPGRTLGYYILHNQDTLEYRRKTRTLRVRMLDGAVKTILVDDSQPVSQLMVVICTKIGITNHEEYGLVREDNEAQNENLPDNKFGTLTLKRKIMEKDRDAKMESLRKKLKTDDEMNWVDVSRTLREQGIDEAETVLLRRRFFFSDQNIDSRDPVQLNLLYVQARDAILDGTHPVTQDKACEFAGIQVHIQFGPHNEAKHKTGFLDLKDFLPQSYVRTKGIEKKIFSEHRKHVDLSEIDAKVLYTKTARELPTYGVTFFLVKEKMNGKNKLVPRLLGVTKDSVLRLDEHTKEILISWPLTTVRRWGASPNTFTLDFGDYANQYYSVQTTEAEQIVQLIAGYIDIILKKKQTKDHFGIEGDEGSTMVEESVAPSKATFLQHETNRMEQLNVESLAHPGIMRPYDGERSYMENEVQTVQYGAFVGQVNHAHQPPTPVVIQCFTKLRKFALVL
InterPro domains: - IPR035963: FERM superfamily, second domain (homologous_superfamily) [203-317]
- IPR019747: FERM conserved site (conserved_site) [181-209]
- IPR029071: Ubiquitin-like domain superfamily (homologous_superfamily) [82-134]
- IPR018979: FERM, N-terminal (domain) [92-140]
- IPR000299: FERM domain (domain) [88-412]
- IPR019749: Band 4.1 domain (domain) [84-322]
- IPR014352: FERM/acyl-CoA-binding protein superfamily (homologous_superfamily) [206-316]
- IPR032425: Talin, N-terminal F0 domain (domain) [4-85]
- IPR002404: IRS-type PTB domain (domain) [322-409]
- IPR019748: FERM central domain (domain) [214-322]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [317-414]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0050839 (cell adhesion molecule binding), GO:0005178 (integrin binding), GO:0005102 (signaling receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0050793 (regulation of developmental process), GO:0007275 (multicellular organism development), GO:0023057 (negative regulation of signaling), GO:0009653 (anatomical structure morphogenesis), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0009791 (post-embryonic development), GO:0048736 (appendage development), GO:0009968 (negative regulation of signal transduction), GO:0002165 (instar larval or pupal development), GO:0010648 (negative regulation of cell communication), GO:0007552 (metamorphosis), GO:0009887 (animal organ morphogenesis), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0010646 (regulation of cell communication), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009966 (regulation of signal transduction), GO:0045595 (regulation of cell differentiation), GO:0035107 (appendage morphogenesis), GO:0009886 (post-embryonic animal morphogenesis), GO:1901185 (negative regulation of ERBB signaling pathway), GO:0045664 (regulation of neuron differentiation), GO:0034329 (cell junction assembly), GO:0048737 (imaginal disc-derived appendage development), GO:0002064 (epithelial cell development), GO:0035120 (post-embryonic appendage morphogenesis), GO:0048707 (instar larval or pupal morphogenesis), GO:0048569 (post-embryonic animal organ development), GO:1901184 (regulation of ERBB signaling pathway), GO:0035114 (imaginal disc-derived appendage morphogenesis), GO:0048563 (post-embryonic animal organ morphogenesis), GO:0007560 (imaginal disc morphogenesis), GO:1902532 (negative regulation of intracellular signal transduction), GO:0007444 (imaginal disc development), GO:0060429 (epithelium development), GO:1902531 (regulation of intracellular signal transduction), GO:0042058 (regulation of epidermal growth factor receptor signaling pathway), GO:0043408 (regulation of MAPK cascade), GO:0035220 (wing disc development), GO:0042058 (regulation of epidermal growth factor receptor signaling pathway), GO:0007476 (imaginal disc-derived wing morphogenesis), GO:0007472 (wing disc morphogenesis), GO:0042059 (negative regulation of epidermal growth factor receptor signaling pathway), GO:0043409 (negative regulation of MAPK cascade), GO:0070373 (negative regulation of ERK1 and ERK2 cascade), GO:0070372 (regulation of ERK1 and ERK2 cascade)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0005911 (cell-cell junction), GO:0043296 (apical junction complex)