Protein: DHRS-12_like_SDR_c-like domain-containing protein (Q6W2N6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MSLYRNSAWFLKGLTEFTKGAFLSASKNFVEKDLETSMAGRSFMITGANSGIGKAAAMAIAKKGGTVHMVCRNKDKAEEARAEIVKESGNKEIYVHILDLSETKKVWEFVESFKKKYKTLNVLINNAGCMMTKREVNGEGLEKSFASNSLAVFIFIKSLIPLLEKSPDPRVITVSSGGMLVQKLRTGNLQSQRGRYDGTMVYAQNKRQQVVMTEQFAKAHPSIHFSVMHPGWVDTPTIANAMPDFHSSMKERLRTTEQGADTVVWLAVSEAAAKNPSGRFYQDRKMVSAHLPLAWTHSSQLEDQKFMSVMEDLAKGFQPH
InterPro domains: - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [37-289]
- IPR052992: Short-chain dehydrogenases/reductases member 12 (family) [1-316]
- IPR002347: Short-chain dehydrogenase/reductase SDR (family) [42-269]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor), GO:0004033 (aldo-keto reductase (NADP) activity), GO:0008106 (alcohol dehydrogenase (NADP+) activity), GO:0052650 (NADP-retinol dehydrogenase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0044237 (cellular metabolic process), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0071704 (organic substance metabolic process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0009887 (animal organ morphogenesis), GO:0010842 (retina layer formation), GO:0009888 (tissue development), GO:0001568 (blood vessel development), GO:0030154 (cell differentiation), GO:0060042 (retina morphogenesis in camera-type eye), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0003407 (neural retina development), GO:0007166 (cell surface receptor signaling pathway), GO:0060041 (retina development in camera-type eye), GO:0035239 (tube morphogenesis), GO:0072001 (renal system development), GO:0048863 (stem cell differentiation), GO:0060562 (epithelial tube morphogenesis), GO:0048514 (blood vessel morphogenesis), GO:0048880 (sensory system development), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0007423 (sensory organ development), GO:0090596 (sensory organ morphogenesis), GO:0035051 (cardiocyte differentiation), GO:0001822 (kidney development), GO:0048794 (swim bladder development), GO:0048793 (pronephros development), GO:0048592 (eye morphogenesis), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0043010 (camera-type eye development), GO:0048593 (camera-type eye morphogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)