Protein: Stathmin (A2A2D0)
Organism: Homo sapiens (Human)
Subcellular location: Cytoplasm, cytoskeleton
Sequence: MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQK
InterPro domains: - IPR030514: Stathmin, conserved site (conserved_site) [40-82]
- IPR036002: Stathmin superfamily (homologous_superfamily) [5-85]
- IPR000956: Stathmin family (family) [3-85]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0009605 (response to external stimulus), GO:0048856 (anatomical structure development), GO:0023057 (negative regulation of signaling), GO:0022402 (cell cycle process), GO:0007049 (cell cycle), GO:0051301 (cell division), GO:0071840 (cellular component organization or biogenesis), GO:0009607 (response to biotic stimulus), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0065009 (regulation of molecular function), GO:0007017 (microtubule-based process), GO:0048523 (negative regulation of cellular process), GO:0051707 (response to other organism), GO:0048585 (negative regulation of response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050790 (regulation of catalytic activity), GO:0009968 (negative regulation of signal transduction), GO:0000910 (cytokinesis), GO:0010648 (negative regulation of cell communication), GO:0044093 (positive regulation of molecular function), GO:0051129 (negative regulation of cellular component organization), GO:1903047 (mitotic cell cycle process), GO:0043207 (response to external biotic stimulus), GO:0035556 (intracellular signal transduction), GO:0044092 (negative regulation of molecular function), GO:0007051 (spindle organization), GO:0048513 (animal organ development), GO:0009966 (regulation of signal transduction), GO:0000226 (microtubule cytoskeleton organization), GO:0051098 (regulation of binding), GO:0032886 (regulation of microtubule-based process), GO:0032970 (regulation of actin filament-based process), GO:0044087 (regulation of cellular component biogenesis), GO:0009888 (tissue development), GO:0010646 (regulation of cell communication), GO:0016043 (cellular component organization), GO:0007166 (cell surface receptor signaling pathway), GO:0051128 (regulation of cellular component organization), GO:0009615 (response to virus), GO:0000278 (mitotic cell cycle), GO:1902850 (microtubule cytoskeleton organization involved in mitosis), GO:0043254 (regulation of protein-containing complex assembly), GO:0007167 (enzyme-linked receptor protein signaling pathway), GO:0051336 (regulation of hydrolase activity), GO:0008277 (regulation of G protein-coupled receptor signaling pathway), GO:0032956 (regulation of actin cytoskeleton organization), GO:0007052 (mitotic spindle organization), GO:0043588 (skin development), GO:1902532 (negative regulation of intracellular signal transduction), GO:1902904 (negative regulation of supramolecular fiber organization), GO:0051099 (positive regulation of binding), GO:0031109 (microtubule polymerization or depolymerization), GO:0031333 (negative regulation of protein-containing complex assembly), GO:0045744 (negative regulation of G protein-coupled receptor signaling pathway), GO:1902903 (regulation of supramolecular fiber organization), GO:0010639 (negative regulation of organelle organization), GO:0070507 (regulation of microtubule cytoskeleton organization), GO:0032231 (regulation of actin filament bundle assembly), GO:0061640 (cytoskeleton-dependent cytokinesis), GO:0008544 (epidermis development), GO:0033043 (regulation of organelle organization), GO:0043933 (protein-containing complex organization), GO:0060429 (epithelium development), GO:0006996 (organelle organization), GO:0022411 (cellular component disassembly), GO:0097435 (supramolecular fiber organization), GO:1904424 (regulation of GTP binding), GO:1902531 (regulation of intracellular signal transduction), GO:0000281 (mitotic cytokinesis), GO:0032272 (negative regulation of protein polymerization), GO:0051058 (negative regulation of small GTPase mediated signal transduction), GO:0051493 (regulation of cytoskeleton organization), GO:0051494 (negative regulation of cytoskeleton organization), GO:0032271 (regulation of protein polymerization), GO:0031113 (regulation of microtubule polymerization), GO:0007019 (microtubule depolymerization), GO:0098773 (skin epidermis development), GO:0031111 (negative regulation of microtubule polymerization or depolymerization), GO:0031115 (negative regulation of microtubule polymerization), GO:0007010 (cytoskeleton organization), GO:0043087 (regulation of GTPase activity), GO:0110020 (regulation of actomyosin structure organization), GO:0007169 (transmembrane receptor protein tyrosine kinase signaling pathway), GO:0051056 (regulation of small GTPase mediated signal transduction), GO:0032984 (protein-containing complex disassembly), GO:0031110 (regulation of microtubule polymerization or depolymerization), GO:0032232 (negative regulation of actin filament bundle assembly), GO:0110053 (regulation of actin filament organization), GO:0051492 (regulation of stress fiber assembly), GO:0046578 (regulation of Ras protein signal transduction), GO:0051497 (negative regulation of stress fiber assembly), GO:0051261 (protein depolymerization), GO:0046580 (negative regulation of Ras protein signal transduction), GO:0061436 (establishment of skin barrier), GO:0035024 (negative regulation of Rho protein signal transduction), GO:0035023 (regulation of Rho protein signal transduction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005615 (extracellular space), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0005576 (extracellular region), GO:0070062 (extracellular exosome), GO:0043227 (membrane-bounded organelle), GO:0043230 (extracellular organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:1903561 (extracellular vesicle)