Protein: Protein transport protein SEC23 D (AtSEC23D) (Protein transport protein SEC23/SEC24-like 1) (AtSec23/Sec24L1) (Protein transport protein SEC24 D) (Q9ZQH3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER) (By similarity). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). May contribute to COPII-coated vesicles formation and ER-Golgi vesicle transport. Together with SEC23A, essential for pollen wall development and exine patterning, probably by regulating endoplasmic reticulum (ER) export of lipids and proteins (e.g. sporopollenin) necessary for pollen wall formation. Also involved in plastid physiology in anther tapetal cells.
Subcellular location: Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000269|PubMed:29390074}; Peripheral membrane protein {ECO:0000250|UniProtKB:P15303}; Cytoplasmic side {ECO:0000250|UniProtKB:P15303}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:29390074}; Peripheral membrane protein {ECO:0000250|UniProtKB:P15303}; Cytoplasmic side {ECO:0000250|UniProtKB:P15303}. Membrane {ECO:0000250|UniProtKB:P15303}; Peripheral membrane protein {ECO:0000250|UniProtKB:P15303}; Cytoplasmic side {ECO:0000250|UniProtKB:P15303}. Note=Observed at endoplasmic reticulum exit sites (ERESs), characteristic for COPII-coated vesicles localization. {ECO:0000269|PubMed:29390074}.
Sequence: MAVRATVSRFPIDSDAQEASGLPWGLTVTPFAAKDENGIGPACGSNGHLLPRCENCYAYFNTYCELDQWAWNCSLCGTLNGLPSDAIARYSNPHSIPEMTSSFIDLEMPLDGSEEEMTQARPVYVAAIDISSSEEFLELTKSALLAALEALSPGALFGLVTFSHKIGLYDVQGPIPVVKNVFIPPDGESSLSLELEDVMPLLQFLAPVETCKDRIAAALETLRPITSWERSAGAGQGMDSVLMGGRGFGTAMEALFNYLGSEFGNTFALARVFAFLSGPPDYGRGQLDTSRYGEQYASKRVDADRALLPEQTPFYKDLATIAVQSGVCVDLFAVTNEYTDLASLKFLSIESGGSLFLYSSTDDSTLPQDMFRMLNRPYAFNCVLRLRTSTEFKPGNSFGHFFPDPQYENLQHIICCDSYATYAYDFEFADNTGFSRHSGEQPVVQIAFQYTVVVPPEGLSNSEMSSSSRGKHTLQRRLRIRTMQFGTAHNINEIYDSVDHEVVLSLLVHKVILASLEDGVREGRALLHDWLVILTAQYNDAFNLVQYKNGNKSMSSQIDITFSQCPQLEPLPRLVFALLRNPLLRFHEEGVHPDYRIYLQCLFSVLDPSSLHCGIYPALMSYSTPDTLAYPRHSLSRAALITSGSPIFFLDAYTTLIVFYSSTADPSIPFPPPQDCLLRQTINKVKQERSITPKLVFIRGGRDDATVFENYLIEEQDVDGNGFASAMGFVSFLDDISQRVTEYMK
InterPro domains: - IPR050550: SEC23/SEC24 family, SEC24 subfamily (family) [3-738]
- IPR036174: Zinc finger, Sec23/Sec24-type superfamily (homologous_superfamily) [46-109]
- IPR006900: Sec23/Sec24, helical domain (domain) [499-611]
- IPR006895: Zinc finger, Sec23/Sec24-type (domain) [51-84]
- IPR036175: Sec23/Sec24 helical domain superfamily (homologous_superfamily) [499-616]
- IPR006896: Sec23/Sec24, trunk domain (domain) [121-373]
- IPR036465: von Willebrand factor A-like domain superfamily (homologous_superfamily) [121-378]
Interaction partners: - Protein transport protein SEC13 homolog B
- Protein transport protein SEC31 homolog B
- Protein transport protein SEC31 homolog A
- Protein transport protein SEC13 homolog A
- Protein transport protein SEC16B homolog
- Protein transport protein SEC16A homolog
- small monomeric GTPase
- Protein transport protein SEC24 C
- Protein transport protein SEC24 B
- Protein transport protein SEC23 B
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0032501 (multicellular organismal process), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0099402 (plant organ development), GO:0046907 (intracellular transport), GO:0045184 (establishment of protein localization), GO:0048731 (system development), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0008104 (protein localization), GO:0015031 (protein transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)