Protein: Uncharacterized serine-rich protein C2F12.03c (O14338)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Not known
Subcellular location: Nucleus {ECO:0000269|PubMed:10759889}.
Sequence: MSAIDSCEHTVSWKLCEQKYNEATTLLSKLKKLLGNFKENCTSVVVDGHKKPRSESRKKYDAKKQHQSSHFATPVKGVESSEPTEKKKRNKEALWLRARQKKWKEIFELCQKITSLLGGTILIDVSFSMEKDVLTYLWMRVHYQVISFFKHRIYEASTQHDPELLSSLVTMHIQYLNSTIQFYTTLIAIIGELYHLQCLSPLTSFFTSCVTPKTILESPLRKQGSHNWKTSTNSQSRLAALFSSIFEDSCLEVDSVKRLLSGSPSSSSSPLKKDSSSNSLTYEPALTDHKPQYLVLCVYRSLIYIGDVHRYLAEVRSPNVPDYQVSRRYYVMAANVAPDYGVHFHQLGLIEVADARSSSRKSSSGQSSSLKGNVNVEDKRLIQALPAISFFFLSSISPNNVAASSAKTSLFIALKRCFGKTNDGSNPCLYHKESSAISLFLRLYAIAFSNTDADYIQDSGPLFKRVRFLLSESLKSGLFSESSLLQMTYCALAARVLAPFIGFSDSGEHGESYPNLKLATQTTTMFFEVLSDSVNSQLPLQALTSGVSSKKDGNFDDLVERRQYGSLSSNAVLMPMLLPLCVLTSSCLQNGDVWLTKDIRTGLSQIFNRLSFFLENTNQTAPDDSVLVRCSSKSIGLLFFFPLVKVCGVPRDTLQWLYFSNHYPFNEEGKGPQVDDSDALITIALDSLYVLLNMRAKSTPNSTSFSSPPTPHRSPFSGQAFTGMGLSNYSLMSSSSFPSAQSSPTSPFLSGTPSIANQSSSIASLQFGRMVDSLVGPVQPIPAQTTGCSVHSLQQRTFSNESPRAVDSGFSRTSTPFSESTSSYPLVSGNLSSCETHLNGSPQNGHLQGERVLFRPLRSPALNTFSTPATEPPEHLVLSELLKKMVNISNN
InterPro domains: - IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [78-721]
- IPR045153: Est1/Ebs1-like (family) [74-660]
- IPR018834: DNA/RNA-binding domain, Est1-type (domain) [326-637]
- IPR019458: Telomerase activating protein Est1-like, N-terminal (domain) [132-315]
Interaction partners: - ATP-dependent helicase upf1
- Nonsense-mediated mRNA decay protein 3
- Nonsense-mediated mRNA decay protein 2
- Eukaryotic translation initiation factor 4 gamma
- CENP-A recruiting complex protein mis19
- Telomerase reverse transcriptase
- CENP-A recruiting complex protein mis20
- SWI/SNF chromatin-remodeling complex subunit sol1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003723 (RNA binding), GO:0043565 (sequence-specific DNA binding), GO:0003697 (single-stranded DNA binding), GO:0042162 (telomeric DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:1901576 (organic substance biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0016043 (cellular component organization), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0090304 (nucleic acid metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0018130 (heterocycle biosynthetic process), GO:0006259 (DNA metabolic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0043933 (protein-containing complex organization), GO:0006996 (organelle organization), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0022607 (cellular component assembly), GO:0071897 (DNA biosynthetic process), GO:0065003 (protein-containing complex assembly), GO:0071824 (protein-DNA complex subunit organization), GO:0000723 (telomere maintenance), GO:0051276 (chromosome organization), GO:0032200 (telomere organization), GO:0065004 (protein-DNA complex assembly), GO:0006278 (RNA-templated DNA biosynthetic process), GO:0010833 (telomere maintenance via telomere lengthening), GO:0007004 (telomere maintenance via telomerase)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098687 (chromosomal region), GO:0000785 (chromatin), GO:0000792 (heterochromatin), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000775 (chromosome, centromeric region), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005721 (pericentric heterochromatin), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome), GO:0005634 (nucleus)