wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Ran GDP/GTP exchange factor (B6K6W4)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Sequence: MLGTWKSLKSKEIRRRYGSYLRMKAMTEKRRQRAVEATEEHDDEHRPIKRSRTGLVTSKTTQPAFHAHRLNHVPKAPTHLLNVYVFGSGSMNELGMADDDVDVIYRPRLNPSLTREKAGVVTLAVGGMHTAVVTHDGRVLTWGVNDDFALGRLTKNQVDEDGEPIDNDTLEGTPYPVEGELLNKHVVKVVCSDNLTVAITDEGECYAWGTFRCSDGILGFSATQKHSPSPTKIDIPEVADVAVGTDHVLALTTAGQVYAWGNGQQCQLGREIPEAVRKEGLVPHLLNLKNILAVGAGSYHSFAVDRDGRVYAWGLNAARQCGIYYENNDEGVIVKEPTLVEALAPFKVESITGGEHHSMAILRGGRVLAWGRHDRHQLGIPEEELPSTVLRDDRGNIYSVPIPTIVPSLVDIVQVCCGTHHNLAIDKHGKAFSWGSGENYEVGQGTDDEDVAIPTLIRSKAIKDVAIKVVGAGGQFSVIAGLPTESTTPKITEKTPAVVRTTEDVSSQSGSITSAFTATSSVFVKDTTVTETVYTSN
InterPro domains: - IPR051553: Ran GTPase-activating (family) [30-486]
- IPR058923: RCC1-like domain (domain) [83-479]
- IPR009091: Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II (homologous_superfamily) [59-501]
- IPR000408: Regulator of chromosome condensation, RCC1 (repeat) [81-483]
Interaction partners: - GTP-binding nuclear protein
- Histone H4
- Importin subunit alpha
- Importin subunit alpha
- Ran GAP Rna1
- Ran GTPase binding protein Sbp1
- Histone H2A
- Histone H2A
- Phosphoprotein phosphatase
- Histone H2B
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0140678 (molecular function inhibitor activity), GO:0060589 (nucleoside-triphosphatase regulator activity), GO:0005085 (guanyl-nucleotide exchange factor activity), GO:0030695 (GTPase regulator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0051302 (regulation of cell division), GO:0051726 (regulation of cell cycle), GO:0051781 (positive regulation of cell division), GO:0090068 (positive regulation of cell cycle process), GO:0010564 (regulation of cell cycle process), GO:0045787 (positive regulation of cell cycle), GO:0032465 (regulation of cytokinesis), GO:0032467 (positive regulation of cytokinesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098687 (chromosomal region), GO:0000785 (chromatin), GO:0043229 (intracellular organelle), GO:0000775 (chromosome, centromeric region), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome)
Protein: cAMP-dependent protein kinase (B6K6I0)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Sequence: MEVKYMSANSGIREQQPFEEGRTQKKYEMAPHAWNEDTVPNRTDTEEGRFNEKNDELVITPEELEKQRQREIRGARIMPLLDLQRKRIRPQTHQTKGRYNMEDFSFSRTLGTGSFGRVHLVQSKHNHLFYAIKVLEKRKVVEMKQVEHSCDERQILSRVQHPFITILWGTFQDARNLFMVMDFVEGGELFSLLRKCHRFPERVARFYAAEVILALDYLHHNQIVYRDLKPENLLLDRGGHVKIVDFGFAKNVSQGNCFTLCGTPDYLAPEIISLKPYNKAVDWWSLGILLFEMLAGYPPFYSNNPMKLYENILESTVKYPSHFSPLATDLISRLLQRDLSKRYGNLKNGSLDIILHPWFEDINWESILTRKVEVPYVPPIRAGTGDSSQFEVYADAPLDYGDNTSPQFTELFQDF
InterPro domains: - IPR008271: Serine/threonine-protein kinase, active site (active_site) [223-235]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [91-390]
- IPR017441: Protein kinase, ATP binding site (binding_site) [110-133]
- IPR000961: AGC-kinase, C-terminal (domain) [360-415]
- IPR000719: Protein kinase domain (domain) [104-359]
Interaction partners: - cAMP-dependent protein kinase regulatory subunit
- Adenylate cyclase
- GTPase Ras1
- Lysophospholipase NTE1
- non-specific serine/threonine protein kinase
- non-specific serine/threonine protein kinase
- mitogen-activated protein kinase
- non-specific serine/threonine protein kinase
- Heterotrimeric G protein beta subunit Git5
- Rheb GTPase Rhb1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity), GO:0004690 (cyclic nucleotide-dependent protein kinase activity), GO:0004691 (cAMP-dependent protein kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0006793 (phosphorus metabolic process), GO:0036211 (protein modification process), GO:0006796 (phosphate-containing compound metabolic process), GO:0043412 (macromolecule modification), GO:0006468 (protein phosphorylation), GO:0016310 (phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0045177 (apical part of cell), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0005938 (cell cortex), GO:0099568 (cytoplasmic region), GO:0045179 (apical cortex), GO:0099738 (cell cortex region)
Protein: Inner centromere protein Mis6 (B6JWB0)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Subcellular location: Chromosome, centromere. Nucleus
Sequence: MTETDENVQSRTTFASFCSCLDAYSLPPKAQLKSIKELYEYVKTVGLSNAEIGLLLSVVLGQKESPFSQGNRVKLIHCLLPTEPVSEDIQLRIVSALDPTGRRVPWTIQTELLRWMMHVFHVCSSTNVLSRNYGILFHFLEFQTFRPYVCPLLVWLTRRKNVRTFRIHHLLALYNRPGNYGDPYLLELIITFKKHYPDVIVGTYEHTKAFSFQWDETWLARLQDILQNAAPLKHALKRLRADSIFPPLQTLQVKPNESSLEENHTAKELSNCIERLKFPSHIASIIAAPPLSQLAFLIISQSLPELSARLDFWVAGALHQAIRDGLHLSYSFHQLSLFLSISKQTMPRTIRLLVDALHQASLSKECVKGIYSVLSSINAESILQYGDEILTLLFKSFLDNDHDPSWIHETEDLFFQWLFTLQSSSQKELGKTIISRMLDGWLETVNRQIKNDTLLYTCLRLFASISAIEYFADIVLTTPFADFVSRATFSPFPPCREAISEYLLHYPGNDRLACNVQNAFLGKASKKGVLLLLRNEQLNLDSLFSNIFNKHDQGSSPSFIKQLPFSNLGSVFSIQLLAHTFRCFTDVERTKLITLSKFLDYELRTKSNEKSRFISSTEQTFSENFNKQLPSFLHSQGFVYFTRFVYAHQNTTTRESELP
InterPro domains: - IPR012485: Centromere protein I (family) [42-227]
Interaction partners: - Tubulin alpha chain
- Tubulin alpha chain
- Dynein heavy chain, cytoplasmic
- Centromere-specific histone H3 CENP-A
- Spindle checkpoint protein Mad2
- Dynein intermediate chain Dic1
- Kinetochore protein Mis16
- EB1 family Mal3
- Microtubule-associated protein Dis1
- Kinetochore protein Mis15
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009893 (positive regulation of metabolic process), GO:0048522 (positive regulation of cellular process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051052 (regulation of DNA metabolic process), GO:0051054 (positive regulation of DNA metabolic process), GO:0045740 (positive regulation of DNA replication), GO:0006275 (regulation of DNA replication), GO:0090329 (regulation of DNA-templated DNA replication), GO:2000105 (positive regulation of DNA-templated DNA replication)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Vacuolar sorting protein Vps24 (B6K517)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Sequence: METIKSFFFKPSLQEQNRKWQSTLRKEQRALDRQNYALKTSKDKAERQIKLLARKNDVHNVRVLAKEVVRLKRHQRRLAESKALLNSLGLQLNEQMANIKIQGAMQSSSKIMHSVSSLSRLPQLSSLMQSLSMEMTKAGVLEEMVDDVLSPAADEEDLLDEIDEEDEEVRQIIAQYMPEAVKSATPSVSVTPQQVSAPEPILDLPSIPKPVEEPVAKDELQESDILDIRGRLDALKS
InterPro domains: - IPR005024: Snf7 family (family) [9-235]
Interaction partners: - Vacuolar sorting protein Did4
- Vacuolar sorting protein Vps20
- Vacuolar-sorting protein SNF7
- Vacuolar sorting protein Did2
- Vacuolar sorting protein
- Vacuolar sorting protein Vps60
- MVB sorting pathway protein
- ESCRT II complex subunit Vps25
- Vacuolar protein sorting-associated protein 28
- vesicle-fusing ATPase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0046907 (intracellular transport), GO:0045184 (establishment of protein localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0008104 (protein localization), GO:0015031 (protein transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0033643 (host cell part), GO:0043657 (host cell), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0033655 (host cell cytoplasm part), GO:0033647 (host intracellular organelle), GO:0030430 (host cell cytoplasm), GO:0033648 (host intracellular membrane-bounded organelle), GO:0044165 (host cell endoplasmic reticulum), GO:0042025 (host cell nucleus)
Protein: Medial ring protein Mid1 (B6JZV3)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Sequence: MSVDAEHVAVYDSADDALPSDYSFTSEKTPLFIERDASFVDQMDQSADERSQNNMASTSDVSMGNMSALNVATDLLESLDLRSMYMRGYGHKDAISGDEDDSVYENDQELPSSTDRLPLQDIPQRPNSKRVPSLTFSCSGTCTSASSTDSASDAMLDAVQQYDTWYRRHQLRSKSLSEEVLSDFDPSRNSSMRSSSRVSHRGSWAPSCRSESVSSRRSNVSTSSKPLPPIPADEPWQPENRALPNVPEPVAAAAAATTTTVAENVEQKEREPSPLPFDYKPLEPLTPIQEAALEDASDTTPVTDLHTPLISRSKVLARVESKRATTSESRISLQEKEILDEIEKFYSDNKSFHSILSHLQSNNQSSAPASREALADSSTINLARGFDADETKSNMYEMSPKSDDEMEDIVIKEVPRHPMSAGNMSTKVVSLRGRIRSSSSFDNLSAIIGSNENSPPMPQKRVVSGTKRVFSNLTPHPSTESVDQYTKSDSPYSSANRSGSDTGTVRFRCTSATSAYPDSIHTYGSMAPPILKRDEAFVPVSRSFDIPRARTAAGARALDVPFPATQYARPHTAMCCTDAYATPNPVKQVTKGKLYLHLADISDVRLLRGERIKKFKCTISTGEHTIQLPWQMVGEQMKMDHDFMFSCSDDMVVDISFTFTRLRTRTKVTKSAVAHTRSKSEQVPSASQKKPKKRGFFSRLFRRGHKKQKVSTKDIRPATTSPLKRSMTAGTPASPQVAVSTTETEEHGHLRLELARLHTKCLGKVHQLALPIVDEKQVEAAGASKLPSESLSVPCVIGRISLRCLYVPPLHMDEDELPNSLEQAEADLQLVKWSKNNKEGYLYVDEKGALQKRFAMLTGKLFVMSEDKGGPELCSFELRSSLLAHPLAEGKQAGPNGINAFGFLMYGPSGERLKCFASSAEAMKSWIDALNKPAARVSKASKLWLQKLVSVLNA
InterPro domains: - IPR001849: Pleckstrin homology domain (domain) [835-937]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [832-937]
Interaction partners: - Riboflavin synthase
- 6,7-dimethyl-8-ribityllumazine synthase
- thymidylate synthase
- GTP cyclohydrolase II
- GTP cyclohydrolase II
- 3,4-dihydroxy-2-butanone 4-phosphate synthase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0008289 (lipid binding), GO:0005543 (phospholipid binding), GO:0035091 (phosphatidylinositol binding), GO:1901981 (phosphatidylinositol phosphate binding), GO:0032266 (phosphatidylinositol-3-phosphate binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0007010 (cytoskeleton organization), GO:0032185 (septin cytoskeleton organization), GO:0031106 (septin ring organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0019867 (outer membrane), GO:0043227 (membrane-bounded organelle), GO:0005740 (mitochondrial envelope), GO:0031968 (organelle outer membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0031966 (mitochondrial membrane), GO:0005741 (mitochondrial outer membrane)
Protein: Glucan endo-1,3-alpha-glucosidase Agn1 (B6K491)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Sequence: MLWLSLLSLVIHLLIQAVSADKEVFAHFIVGNTYPYTVSDWQADIQEAVATGIDGFALNMGSDAWQVERIDDAFTAAASVSSSFKLFISFDMSVISADATFIEGVVRRFANKPNQFWYNGKIFVSTFAGEVDTFGYTDESSGWQNAIKEPLAEAGYPIFFAPSWTSLGTGALNLAVTDGFFSWNSWPTSSNDMNDNDDISYQQLANSLGKLYIAPVSPWFFTHLSYKNFVYKSDWLIMDRWQEMLDMQPDMIEVISWNDFGESHYMGSIRGALPAGSDVYVDGFDHKAWRYLMYPYIDAYKNGLSAPQVTFESLFYWYRPTSKYAVATSDSYGYPSGGDYMEDNIYVAVYLLDAAEVTITSGSNSQTFSGVAGVNRFSIAFETDTTPSFSVSRGGLVMASGTGPEITSSTASYNFNAYTGHLFF
InterPro domains: - IPR005197: Glycoside hydrolase family 71 (family) [18-398]
Interaction partners: - glucan endo-1,3-beta-D-glucosidase
- Deoxyuridine 5'-triphosphate nucleotidohydrolase
- DNA repair endonuclease XPF
- Coenzyme A/diphosphate transporter
- Transcription factor CBF/NF-Y/archaeal histone domain-containing protein
- Fungal protein
- Replication protein A subunit
- Crossover junction endonuclease MUS81
- Nuclear transport factor 2
- Medial ring protein Mid2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds), GO:0015926 (glucosidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009056 (catabolic process), GO:0044237 (cellular metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:1901575 (organic substance catabolic process), GO:0044248 (cellular catabolic process), GO:0005975 (carbohydrate metabolic process), GO:0044262 (cellular carbohydrate metabolic process), GO:0016052 (carbohydrate catabolic process), GO:0044275 (cellular carbohydrate catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Reticulon-like protein (B6JZ25)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Subcellular location: Endoplasmic reticulum membrane; Multi- pass membrane protein
Sequence: MSSSEPTHNPFQAPNRVAEEEQVLDNLHSATDAASEKLNDLLHSASANVGKTTPATSAHVDPDFFSNLAGSGSHSEPKAASEQAGEGSCPVATSSHHPEKPTSVLDDKSYVAVDSSVPEGTTCPVSNSSVENVKCPVSGSAGKAGICPAKNVHDNKMDIPVSEEEAKENAGKACPFSKATVDSQQKVASCPVNVCQSDDKTCPVVDAGCLFEYKPLTAEQKQFQGAFVDVLLWKNKYCSMSVLAAIFTALYLPCVLSIHRNLFNISSWIFGVSAVVEYVSRIITGGKSGVLGRFRNNQFFTLNKGSIHACLDSVIEPVNCMLVELQRLFLAENPCKSVSAFFLAWFYYRMSLLLSLKTIFALSVIAAFSLPPFYQANKRVIDGTLSNIKFQIEEYTCQFRKTAESKGRAASQKVADALNLQKKTA
InterPro domains: - IPR003388: Reticulon (domain) [227-425]
Interaction partners: - Protein sey1
- Eukaryotic protein
- Protein YOP1
- Spindle pole body docking protein Cut11
- MSP domain-containing protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0010256 (endomembrane system organization), GO:0007029 (endoplasmic reticulum organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Nuclear pore complex protein Nup85 (B6JVQ6)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Function: Functions as a component of the nuclear pore complex (NPC)
Subcellular location: Nucleus, nuclear pore complex
Sequence: MSTYEETIHEPQEEPLVYHINDAPIKDSESWEQSDGTIGFSLHPYLAQGASYITTKKVNSTSTAASLIPKSEVFELQVPSYVVEPETLLVEWADLWNELQQYNFSTVLEAQQFQQSFLKRVSFLFREKLKPALQNLQDQINEGKKNLQPSLNTLWEVASAWKCAEALYLSSPEEPTLAFGIMDWVNSYDPQPSIKDGMEIMTYEVPHQHPEFWSYVFKTALRGLFEQTVSCLDSSSLILESASLKSCIPEIIDIIQAAPHKQKRTHSKFDFEKHWRRWRARVLGMRETVFADEGLNTHYRENLDLLLRVLSGDQDVLRSLSNHWQEYFGALCYLYDPVGCDDVNGASILYEIATAPETGYLPDVTLEFECVCSYLCKKKPLEAVQHAFLLDLGFSVHLTDLLTKSGYLENFVTSKFPVTLREHLILEFGNAVLQSTGNWKVAYSYWKYVPNFGPQRIKESISHVEIKSQDDVQSALQFCAELDLEDERKSILSHWAQLLVQKGEYGEACLHMNKAEDVISLNRLNWNLFEKLLDSKKPLDSLDSTMLHLMSSPMECPAVLATMLAPLATLNQYFSLRENGQISQAISSLVAILKADGLPKKYFFPLLSELSSFISYLFEDEENRVKLMSLNDTYDCIASLEDHRSDDDFDKPQVITLRKQLAHITARLFLLK
InterPro domains: - IPR011502: Nucleoporin Nup85-like (family) [30-660]
Interaction partners: - NUP37 family WD repeat protein
- Nucleoporin Nup131
- Nucleoporin Seh1
- COPII-coated vesicle component Sec13
- Nucleoporin Nup189
- Nucleoporin Nup120
- Nuclear pore complex protein
- Nucleoporin Nup157/170
- Nucleoporin Nup132
- Nucleoporin Nup186
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051641 (cellular localization), GO:0071704 (organic substance metabolic process), GO:0033036 (macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0051236 (establishment of RNA localization), GO:0046907 (intracellular transport), GO:0006810 (transport), GO:0006403 (RNA localization), GO:0043170 (macromolecule metabolic process), GO:0071702 (organic substance transport), GO:0050658 (RNA transport), GO:0051169 (nuclear transport), GO:0071705 (nitrogen compound transport), GO:0010467 (gene expression), GO:0015931 (nucleobase-containing compound transport), GO:0006913 (nucleocytoplasmic transport), GO:0051028 (mRNA transport), GO:0006406 (mRNA export from nucleus), GO:0006405 (RNA export from nucleus), GO:0051168 (nuclear export), GO:0050657 (nucleic acid transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0140513 (nuclear protein-containing complex), GO:0012505 (endomembrane system), GO:0031967 (organelle envelope), GO:0031080 (nuclear pore outer ring), GO:0005635 (nuclear envelope), GO:0005643 (nuclear pore), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Myosin II regulatory light chain Rlc1 (B6JYK4)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Sequence: MTSKNKRLPKSLPSKLVTSKRINSGTFSQLTTSQIQELKEAFALLDKDGDGVVDRDDLKSMLTSLNQDASDEALDQMLSEVNPPINLASFLTAIGSMLCKISPRADLMEAFYTIEDTQSGKMSLRSFEEALSRSGSDIKGSELEDVIRPYTNHGTFYYEKFVNAIAGTKEN
InterPro domains: - IPR002048: EF-hand domain (domain) [33-81]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [46-58]
- IPR011992: EF-hand domain pair (homologous_superfamily) [30-165]
- IPR050403: Myosin regulatory light chain (family) [17-168]
Interaction partners: - Myosin type-2 heavy chain 1
- Myosin type-2 heavy chain 2
- Uncharacterized protein
- Tropomyosin
- Nucleoporin Nup60
- Paxillin-like protein Pxl1
- Actin
- Actin Act1
- Myosin II light chain
- Alpha-actinin
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051301 (cell division), GO:0071840 (cellular component organization or biogenesis), GO:0030029 (actin filament-based process), GO:0022402 (cell cycle process), GO:0007049 (cell cycle), GO:0032506 (cytokinetic process), GO:0016043 (cellular component organization), GO:0000910 (cytokinesis), GO:1903047 (mitotic cell cycle process), GO:0044837 (actomyosin contractile ring organization), GO:0030036 (actin cytoskeleton organization), GO:0000278 (mitotic cell cycle), GO:0036213 (contractile ring contraction), GO:0000916 (actomyosin contractile ring contraction), GO:0061640 (cytoskeleton-dependent cytokinesis), GO:0030866 (cortical actin cytoskeleton organization), GO:0006996 (organelle organization), GO:1902410 (mitotic cytokinetic process), GO:0031032 (actomyosin structure organization), GO:0000281 (mitotic cytokinesis), GO:0007010 (cytoskeleton organization), GO:0030865 (cortical cytoskeleton organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015629 (actin cytoskeleton)