Protein: Cathepsin B-like cysteine proteinase 3 (EC 3.4.22.-) (Cysteine protease-related 3) (P43507)
Organism: Caenorhabditis elegans
Function: Not known
Sequence: MLKVYFLALFLAGCSAFVLDEIRGINIGQSPQKVLVDHVNTVQTSWVAEHNEISEFEMKFKVMDVKFAEPLEKDSDVASELFVRGEIVPEPLPDTFDAREKWPDCNTIKLIRNQATCGSCWAFGAAEVISDRVCIQSNGTQQPVISVEDILSCCGTTCGYGCKGGYSIEALRFWASSGAVTGGDYGGHGCMPYSFAPCTKNCPESTTPSCKTTCQSSYKTEEYKKDKHYGASAYKVTTTKSVTEIQTEIYHYGPVEASYKVYEDFYHYKSGVYHYTSGKLVGGHAVKIIGWGVENGVDYWLIANSWGTSFGEKGFFKIRRGTNECQIEGNVVAGIAKLGTHSETYEDDGGAATSCSFIMCTLMVLTYYFV
InterPro domains: - IPR013128: Peptidase C1A (family) [64-328]
- IPR025661: Cysteine peptidase, asparagine active site (active_site) [299-318]
- IPR000169: Cysteine peptidase, cysteine active site (active_site) [114-125]
- IPR000668: Peptidase C1A, papain C-terminal (domain) [92-335]
- IPR038765: Papain-like cysteine peptidase superfamily (homologous_superfamily) [35-334]
- IPR025660: Cysteine peptidase, histidine active site (active_site) [282-292]
Interaction partners: - Aspartic protease 3
- Aspartic protease 4
- legumain
- Neprilysin-2
- Actin
- Neprilysin-1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008234 (cysteine-type peptidase activity), GO:0004175 (endopeptidase activity), GO:0004197 (cysteine-type endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0051641 (cellular localization), GO:0019098 (reproductive behavior), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0042303 (molting cycle), GO:0022404 (molting cycle process), GO:0050794 (regulation of cellular process), GO:0051234 (establishment of localization), GO:0032504 (multicellular organism reproduction), GO:0007610 (behavior), GO:0009791 (post-embryonic development), GO:0048522 (positive regulation of cellular process), GO:0035295 (tube development), GO:0010171 (body morphogenesis), GO:0035239 (tube morphogenesis), GO:0048856 (anatomical structure development), GO:0010942 (positive regulation of cell death), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0010941 (regulation of cell death), GO:0048731 (system development), GO:0006810 (transport), GO:0048513 (animal organ development), GO:0018991 (oviposition), GO:0051649 (establishment of localization in cell), GO:0009790 (embryo development), GO:0048608 (reproductive structure development), GO:0002164 (larval development), GO:0045137 (development of primary sexual characteristics), GO:0007548 (sex differentiation), GO:0009886 (post-embryonic animal morphogenesis), GO:0018996 (molting cycle, collagen and cuticulin-based cuticle), GO:0097164 (ammonium ion metabolic process), GO:0061458 (reproductive system development), GO:0055123 (digestive system development), GO:0043067 (regulation of programmed cell death), GO:0043068 (positive regulation of programmed cell death), GO:0048569 (post-embryonic animal organ development), GO:0008406 (gonad development), GO:0071702 (organic substance transport), GO:0016192 (vesicle-mediated transport), GO:0002119 (nematode larval development), GO:0048546 (digestive tract morphogenesis), GO:0048565 (digestive tract development), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043065 (positive regulation of apoptotic process), GO:0042981 (regulation of apoptotic process), GO:0006909 (phagocytosis), GO:0040025 (vulval development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane), GO:0098857 (membrane microdomain), GO:0045121 (membrane raft)