Protein: Cadherin-13 (Q8VDK4)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Sequence: MQPRTPLTLCVLLSQVLLVTSADDLECTPGFQQKVLHIHQPAEFIEDQPVLNLTFSDCKGNEKLHYEVSSPHFKVNSDGTLVALRNITAVGRTLFVHARTPHAEDMAELVIVGGKDIQGSLQDIFKFARTSPVPRQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRPEGSKFRLTGKGVDQDPKGTFRINENTGSVSVTRTLDRETIATYQLYVETTDASGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIVIDDKNDHSPKFTKKEFQATVEEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEGPVFYPDPMMVTKQENISVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLSINPINGTVDTTAVLDRESPFVHNSVYTALFLAIDSGNPPATGTGTLLITLEDINDNAPVIYPTVAEVCDDARNLSVVILGASDKDLHPNTDPFKFEIHKQTVPDKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCKNSKVDCNGAGALHLSLSLLLLFSLLSLLSGL
InterPro domains: - IPR014868: Cadherin prodomain (domain) [26-112]
- IPR002126: Cadherin-like (domain) [145-695]
- IPR039808: Cadherin (family) [119-690]
- IPR015919: Cadherin-like superfamily (homologous_superfamily) [22-683]
- IPR020894: Cadherin conserved site (conserved_site) [351-583]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0042562 (hormone binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0051641 (cellular localization), GO:0023056 (positive regulation of signaling), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048870 (cell motility), GO:0042221 (response to chemical), GO:0090130 (tissue migration), GO:0048584 (positive regulation of response to stimulus), GO:0019222 (regulation of metabolic process), GO:0007155 (cell adhesion), GO:0008283 (cell population proliferation), GO:0032879 (regulation of localization), GO:0071840 (cellular component organization or biogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0009653 (anatomical structure morphogenesis), GO:0048522 (positive regulation of cellular process), GO:0009719 (response to endogenous stimulus), GO:0040017 (positive regulation of locomotion), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0009893 (positive regulation of metabolic process), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0040012 (regulation of locomotion), GO:0009967 (positive regulation of signal transduction), GO:0032103 (positive regulation of response to external stimulus), GO:0051049 (regulation of transport), GO:0044085 (cellular component biogenesis), GO:2000145 (regulation of cell motility), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0035556 (intracellular signal transduction), GO:0098609 (cell-cell adhesion), GO:0050920 (regulation of chemotaxis), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0008285 (negative regulation of cell population proliferation), GO:0009966 (regulation of signal transduction), GO:0090132 (epithelium migration), GO:0030155 (regulation of cell adhesion), GO:0060255 (regulation of macromolecule metabolic process), GO:0032101 (regulation of response to external stimulus), GO:0060627 (regulation of vesicle-mediated transport), GO:0045785 (positive regulation of cell adhesion), GO:0051668 (localization within membrane), GO:0010033 (response to organic substance), GO:2000147 (positive regulation of cell motility), GO:0009891 (positive regulation of biosynthetic process), GO:0071402 (cellular response to lipoprotein particle stimulus), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0042127 (regulation of cell population proliferation), GO:1901698 (response to nitrogen compound), GO:0007162 (negative regulation of cell adhesion), GO:0010646 (regulation of cell communication), GO:0031325 (positive regulation of cellular metabolic process), GO:0050673 (epithelial cell proliferation), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0016043 (cellular component organization), GO:0031323 (regulation of cellular metabolic process), GO:0010647 (positive regulation of cell communication), GO:0055094 (response to lipoprotein particle), GO:0080090 (regulation of primary metabolic process), GO:0051128 (regulation of cellular component organization), GO:0050921 (positive regulation of chemotaxis), GO:0008284 (positive regulation of cell population proliferation), GO:0016477 (cell migration), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0035239 (tube morphogenesis), GO:0030100 (regulation of endocytosis), GO:0010811 (positive regulation of cell-substrate adhesion), GO:0010631 (epithelial cell migration), GO:0050926 (regulation of positive chemotaxis), GO:0030030 (cell projection organization), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010810 (regulation of cell-substrate adhesion), GO:0001944 (vasculature development), GO:0048661 (positive regulation of smooth muscle cell proliferation), GO:0043616 (keratinocyte proliferation), GO:0030334 (regulation of cell migration), GO:0050678 (regulation of epithelial cell proliferation), GO:0010468 (regulation of gene expression), GO:0050679 (positive regulation of epithelial cell proliferation), GO:0001667 (ameboidal-type cell migration), GO:0022607 (cellular component assembly), GO:0048660 (regulation of smooth muscle cell proliferation), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0050927 (positive regulation of positive chemotaxis), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0098742 (cell-cell adhesion via plasma-membrane adhesion molecules), GO:0010243 (response to organonitrogen compound), GO:0048514 (blood vessel morphogenesis), GO:0072359 (circulatory system development), GO:0071404 (cellular response to low-density lipoprotein particle stimulus), GO:0031326 (regulation of cellular biosynthetic process), GO:1901184 (regulation of ERBB signaling pathway), GO:0030335 (positive regulation of cell migration), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:1902533 (positive regulation of intracellular signal transduction), GO:0051252 (regulation of RNA metabolic process), GO:0007264 (small GTPase mediated signal transduction), GO:0002040 (sprouting angiogenesis), GO:0031328 (positive regulation of cellular biosynthetic process), GO:1902531 (regulation of intracellular signal transduction), GO:0042058 (regulation of epidermal growth factor receptor signaling pathway), GO:0043408 (regulation of MAPK cascade), GO:2001141 (regulation of RNA biosynthetic process), GO:0001952 (regulation of cell-matrix adhesion), GO:0120036 (plasma membrane bounded cell projection organization), GO:0006355 (regulation of DNA-templated transcription), GO:0043542 (endothelial cell migration), GO:0007265 (Ras protein signal transduction), GO:0016339 (calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules), GO:0007156 (homophilic cell adhesion via plasma membrane adhesion molecules), GO:0050848 (regulation of calcium-mediated signaling), GO:0001936 (regulation of endothelial cell proliferation), GO:0001954 (positive regulation of cell-matrix adhesion), GO:1902680 (positive regulation of RNA biosynthetic process), GO:0006357 (regulation of transcription by RNA polymerase II), GO:0007266 (Rho protein signal transduction), GO:0045893 (positive regulation of DNA-templated transcription), GO:0097581 (lamellipodium organization), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:0120031 (plasma membrane bounded cell projection assembly), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0016601 (Rac protein signal transduction), GO:0045944 (positive regulation of transcription by RNA polymerase II), GO:0030032 (lamellipodium assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098552 (side of membrane), GO:0009986 (cell surface), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0009897 (external side of plasma membrane), GO:0005886 (plasma membrane)