wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Flagellin B (Q56572)
Organism: Vibrio anguillarum (Listonella anguillarum)
Function: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. FlaB is not essential for flagellar synthesis and motility.
Subcellular location: Secreted. Bacterial flagellum.
Sequence: MAINVSTNVSAMTAQRYLNNAADGTQKSMERLSSGYKINSARDDAAGLQISNRLTSQSRGLDMAVRNANDGISIAQTAEGAMNETTNILQRMRDLSLQSANGSNSSSERQAIQEEVSALNDELNRIAETTSFGGNKLLNGSFGNKSFQIGADSGEAVMLSMSDMRSDTKAMGGKSYVATNGKAPDWSVTNATDLTLSYTDKQGEAREVTINAKAGDDLEEVATYINGQNGDIKASVGDEGKLQLFAANQKVSSDVTIGGGLGTEIGFAAGKDVTVKDINVTTVGGSQEAVALIDGALKAVDSQRASLGAFQNRFGHAISNLDNINENVNASRSRIKDTDYARETTQMTKSQILQQASTSVLAQAKQSPSAALSLLG
InterPro domains: - IPR042187: Flagellin, C-terminal domain, subdomain 2 (homologous_superfamily) [327-375]
- IPR046358: Flagellin, C-terminal domain (domain) [291-375]
- IPR010810: Flagellin hook, IN motif (conserved_site) [193-248]
- IPR001029: Flagellin, N-terminal domain (domain) [5-141]
- IPR001492: Flagellin (family) [4-376]
Interaction partners: - Flagellar secretion chaperone FliS
- Flagellar filament capping protein FliD
- Protein FlaG
- Flagellum-specific ATP synthase
- Flagellar motor switch protein FliG
- Flagellar motor switch protein FliN
- Flagellar basal-body rod protein FlgC
- Flagellar hook-associated protein FlgK
- Flagellar biosynthesis protein FlgE
- Flagellar biosynthesis protein FlhB
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0048870 (cell motility), GO:0001539 (cilium or flagellum-dependent cell motility), GO:0097588 (archaeal or bacterial-type flagellum-dependent cell motility), GO:0071973 (bacterial-type flagellum-dependent cell motility)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0043228 (non-membrane-bounded organelle), GO:0099081 (supramolecular polymer), GO:0120025 (plasma membrane bounded cell projection), GO:0005929 (cilium), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0099513 (polymeric cytoskeletal fiber), GO:0005884 (actin filament), GO:0015629 (actin cytoskeleton)
Protein: TSC22D4 protein (Q8IV54)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MSGGKKKSSFQITSVTTDYEGPGSPGASDPPTPQPPTGPPPRLPNGEPSPDPGGKGTPRNGSPPPGAPSSRFRVVKLPHGLGEPYRRGRWTCVDVYERDLEPHSFGGLLEGIRGASGGAGGRSLDSRLELASLGLGAPTPPSGLSQGPTSWLRPPPTSPGPQARSFTGGLGQLVVPSKAKAEKPPLSASSPQQRPPEPETGESAGTSRAATPLPSLRVEAEAGGSGARTPPLSRRKAVDMRLRMELGAPEEMGQVPPLDSRPSSPALYFTHDASLVHKSPDPFGAVAAQKFSLAHSMLAISGHLDSDDDR
InterPro domains: - IPR042553: TSC22 domain family protein 4 (family) [1-309]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048522 (positive regulation of cellular process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009891 (positive regulation of biosynthetic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0010468 (regulation of gene expression), GO:1902680 (positive regulation of RNA biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0006357 (regulation of transcription by RNA polymerase II), GO:0045893 (positive regulation of DNA-templated transcription), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045944 (positive regulation of transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Transmembrane protein 87B (Q96K49)
Organism: Homo sapiens (Human)
Function: May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN).
Subcellular location: Golgi apparatus membrane {ECO:0000305|PubMed:26157166}; Multi-pass membrane protein {ECO:0000255}.
Sequence: MVAACRSVAGLLPRRRRCFPARAPLLRVALCLLCWTPAAVRAVPELGLWLETVNDKSGPLIFRKTMFNSTDIKLSVKSFHCSGPVKFTIVWHLKYHTCHNEHSNLEELFQKHKLSVDEDFCHYLKNDNCWTTKNENLDCNSDSQVFPSLNNKELINIRNVSNQERSMDVVARTQKDGFHIFIVSIKTENTDASWNLNVSLSMIGPHGYISASDWPLMIFYMVMCIVYILYGILWLTWSACYWKDILRIQFWIAAVIFLGMLEKAVFYSEYQNISNTGLSTQGLLIFAELISAIKRTLARLLVIIVSLGYGIVKPRLGTVMHRVIGLGLLYLIFAAVEGVMRVIGGSNHLAVVLDDIILAVIDSIFVWFIFISLAQTMKTLRLRKNTVKFSLYRHFKNTLIFAVLASIVFMGWTTKTFRIAKCQSDWMERWVDDAFWSFLFSLILIVIMFLWRPSANNQRYAFMPLIDDSDDEIEEFMVTSENLTEGIKLRASKSVSNGTAKPATSENFDEDLKWVEENIPSSFTDVALPVLVDSDEEIMTRSEMAEKMFSSEKIM
InterPro domains: - IPR009637: Transmembrane protein GPR107/GPR108-like (family) [112-523]
- IPR054101: TMEM87A/B, GOLD domain (domain) [44-174]
- IPR053937: GOST, seven transmembrane domain (domain) [215-458]
Interaction partners: - Fibulin-7
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport), GO:0048193 (Golgi vesicle transport), GO:0006890 (retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0005773 (vacuole), GO:0031090 (organelle membrane), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0005774 (vacuolar membrane), GO:0098588 (bounding membrane of organelle), GO:0005764 (lysosome), GO:0098852 (lytic vacuole membrane), GO:0005765 (lysosomal membrane)
Protein: BTB domain-containing protein (Q20476)
Organism: Caenorhabditis elegans
Function: Not known
Sequence: MLARASLHSNGVDMHTAEYADYKKAEVTSHHARDIVHINAGGTRFTTLYDTLAQSKSSYFLNFIRIDRTSGKIVLLQQRTIRDESGAIFVNRDGRLFAFVLQFMRDGKNTVLPKDKDVLAQLKREADFFGMEVFKYLIQETLVDIEKEQRANTNDIVDIRNSVNQIANNTYYNNGGRI
InterPro domains: - IPR003131: Potassium channel tetramerisation-type BTB domain (domain) [36-132]
- IPR000210: BTB/POZ domain (domain) [34-146]
- IPR011333: SKP1/BTB/POZ domain superfamily (homologous_superfamily) [27-147]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0032501 (multicellular organismal process), GO:0051239 (regulation of multicellular organismal process), GO:0007610 (behavior), GO:0050795 (regulation of behavior), GO:0007626 (locomotory behavior), GO:0060259 (regulation of feeding behavior), GO:1903998 (regulation of eating behavior), GO:0043051 (regulation of pharyngeal pumping)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0055120 (striated muscle dense body), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0030054 (cell junction), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043229 (intracellular organelle), GO:0043292 (contractile fiber), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0099512 (supramolecular fiber)
Protein: Secretoglobin, family 2B, member 27 (A0A087WRN7)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Sequence: MKGTLLLLALLVTGELGFQTTEACAPFVGAYVKILGGNRLALNAYLSMFQATAAERVAFEKIQDCFNEEPLTTKLKSPQIMT
InterPro domains: - IPR035960: Secretoglobin superfamily (homologous_superfamily) [22-82]
- IPR015332: Major allergen I polypeptide chain 2-like (family) [1-82]
- IPR016126: Secretoglobin (family) [22-82]
- IPR053723: Secretoglobin Domain-Containing (homologous_superfamily) [1-82]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:0008289 (lipid binding), GO:0005496 (steroid binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:0006952 (defense response), GO:1901700 (response to oxygen-containing compound), GO:0010035 (response to inorganic substance), GO:0043207 (response to external biotic stimulus), GO:0006979 (response to oxidative stress), GO:0010033 (response to organic substance), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0002237 (response to molecule of bacterial origin), GO:0032496 (response to lipopolysaccharide), GO:0033993 (response to lipid), GO:0000302 (response to reactive oxygen species)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: 48 related 2, isoform E (A0A0B4LH77)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MSRNQLPDSSSSPPISHLPFHNFDDDLINDLPSCIYAGQHQGGGATGGGGGSGGGGGSSGLRLSSNNLRHIQQHYMQHSGENLLDSSTNPMGVHNSGGGAPLMCNSPSASSSGGGCGNAGSATPGGAGGPNPGYGSVGAATASSYKMQRQAANVRERKRIQSSINSAFDELRVHVPTFPYEKRLSKIDTLRLAIAYISLLREVLQTDYDPLTYVEKCLRGEIKADRANWNTNLTARLSWINWENLGVHPGRRTLLTSLALSSEPMCGAHCGMP
InterPro domains: - IPR011598: Myc-type, basic helix-loop-helix (bHLH) domain (domain) [148-206]
- IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [139-209]
- IPR050283: E-box Binding Transcriptional Regulators (family) [119-209]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0006950 (response to stress), GO:0048523 (negative regulation of cellular process), GO:0050794 (regulation of cellular process), GO:0060548 (negative regulation of cell death), GO:0010941 (regulation of cell death), GO:0006979 (response to oxidative stress), GO:0080134 (regulation of response to stress), GO:0080135 (regulation of cellular response to stress), GO:1900407 (regulation of cellular response to oxidative stress), GO:1901214 (regulation of neuron death), GO:1901215 (negative regulation of neuron death), GO:1903201 (regulation of oxidative stress-induced cell death), GO:1903202 (negative regulation of oxidative stress-induced cell death), GO:1902882 (regulation of response to oxidative stress), GO:1903203 (regulation of oxidative stress-induced neuron death), GO:1903204 (negative regulation of oxidative stress-induced neuron death)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Alpha-1-acid glycoprotein (Orosomucoid) (OMD) (P02764)
Organism: Rattus norvegicus (Rat)
Function: Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain (By similarity). Appears to function in modulating the activity of the immune system during the acute-phase reaction.
Subcellular location: Secreted {ECO:0000250}.
Sequence: MALHMVLVVLSLLPLLEAQNPEPANITLGIPITNETLKWLSDKWFYMGAAFRDPVFKQAVQTIQTEYFYLTPNLINDTIELREFQTTDDQCVYNFTHLGVQRENGTLSKCAGAVKIFAHLIVLKKHGTFMLAFNLTDENRGLSFYAKKPDLSPELRKIFQQAVKDVGMDESEIVFVDWTKDKCSEQQKQQLELEKETKKETKKDP
InterPro domains: - IPR012674: Calycin (homologous_superfamily) [19-191]
- IPR000566: Lipocalin/cytosolic fatty-acid binding domain (domain) [42-179]
- IPR001500: Alpha-1-acid glycoprotein (family) [1-204]
Interaction partners: - Albumin
- Haptoglobin
- Alpha-1-antiproteinase
- Alpha-2-macroglobulin
- Transthyretin
- Ceruloplasmin
- Alpha-2-HS-glycoprotein
- Hemopexin
- Vitamin D-binding protein
- Protein AMBP
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:0043167 (ion binding), GO:0008289 (lipid binding), GO:0043168 (anion binding), GO:0043177 (organic acid binding), GO:0019840 (isoprenoid binding), GO:0031406 (carboxylic acid binding), GO:0005501 (retinoid binding), GO:0033293 (monocarboxylic acid binding), GO:0001972 (retinoic acid binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0044706 (multi-multicellular organism process), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0044703 (multi-organism reproductive process), GO:1901700 (response to oxygen-containing compound), GO:0007565 (female pregnancy), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0048545 (response to steroid hormone), GO:0014070 (response to organic cyclic compound), GO:1901654 (response to ketone), GO:0033993 (response to lipid), GO:0032570 (response to progesterone)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: HTH myb-type domain-containing protein (A0A178VYP6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MIPSMEGGGKTNREEEEEEEEEEEEGEESKVSSNSTVEESDKKTKVRPYVRSKVPRLRWTPDLHLRFVRAVERLGGQERATPKLVRQMMNIKGLSIAHVKSHLQMYRSKKIDDQGQAIAGHKHLFETSTDRNIYKLSQLPMFRGYNHNHDSPFRYGSKISNASLWNSSSQGTERSLIDQIRPGLIRNASVSNNIRGSDYWTNNKSFQNIYSSSISNHFPKLRHDHHERTNSVTFNSIQGHSRTFQKFHNGVEENTNHSYCSKTNGKRDASRSIDLDLSLKLRQPEKTILEETETAATTTDQTLSLSLCPGSSSWKKSRLMKDEEDRTVKIGQESTLDLTL
InterPro domains: - IPR001005: SANT/Myb domain (domain) [56-107]
- IPR046955: Myb family transcription factor PHR1-like (family) [41-274]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [53-109]
- IPR017930: Myb domain (domain) [51-111]
- IPR006447: Myb domain, plants (domain) [55-110]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: UDP-glycosyltransferase 73C13 (EC 2.4.1.368) (Oleanolate 3-O-glucosyltransferase UGT73C13) (K4GHS2)
Organism: Barbarea vulgaris (Yellow rocket) (Erysimum barbarea)
Function: Catalyzes the transfer of a glucose (Glc) moiety from UDP-Glc to the C-3 position of the oleanane sapogenins oleanolate and hederagenin, and to the C-28 carboxylic group of the lupane sapogenin betulinate. The monoglucosylated hederagenin 3-O-beta-D-glucoside is a feeding deterrent of the yellow-striped flea beetle (Phyllotreta nemorum).
Sequence: MVSEITHKSYPLHFVLFPFMAQGHMIPMVDIARLLAQRGVKITIVTTPHNAARFENVLNRAIESGLPISIVQVKLPSQEAGLPEGNETFDSLVSMELLVPFFKSVNMLEEPVQKLFEEMSPQPSCIISDFCLPYTSKIAKKFNIPKILFHGMCCFCLLCMHVLRKNHEIVENLKSDKEHFVVPYFPDRVEFTRPQVPVATYVPGDWHEITGDMVEADKTSYGVIVNTCQELEPAYANDYKEARSGKAWTIGPVSLCNKVGADKAERGNKADIDQDECLKWLNSKEEGSVLYVCLGSICNLPLSQLKELGLGLEESQRPFIWVIRGWEKNKELLEWFSESGFEERIKDRGLLIKGWAPQMLILSHHSVGGFLTHCGWNSTLEGLTAGLPLLTWPLFADQFCNEKLAVQVLKAGVSAGVDQPMKWGEEEKIGVLVDKEGVKKAVEELMGESDDAKEIRRRAKELGELAHKAVEEGGSSHSNITSLLEDIMQLAQSNN
InterPro domains: - IPR002213: UDP-glucuronosyl/UDP-glucosyltransferase (family) [12-479]
- IPR035595: UDP-glycosyltransferase family, conserved site (conserved_site) [355-398]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0008194 (UDP-glycosyltransferase activity), GO:0046527 (glucosyltransferase activity), GO:0035251 (UDP-glucosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0071704 (organic substance metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:1901657 (glycosyl compound metabolic process), GO:0016137 (glycoside metabolic process), GO:0016134 (saponin metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Type 3 secretion system stator protein (T3SS stator protein) (Low calcium response locus protein KC) (Yop proteins translocation protein L) (P69976)
Organism: Yersinia pestis
Function: Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (Probable). Acts as a regulator of the YscN/SctN ATPase activity (By similarity).
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q01253}.
Sequence: MSQTCQTGYAYMQPFVQIIPSNLSLACGLRILRAEDYQSSLTTEELISAAKQDAEKILADAQEVYEQQKQLGWQAGMDEARTLQATLIHETQLQCQQFYRHVEQQMSEVVLLAVRKILNDYDQVAMTLQVVREALALVSNQKQVVVRVNPDQAGAIREQIAKVHKDFPEISYLEVTADARLDQGGCILETEVGIIDASIDGQIEALSRAISTTLGQMKVTE
InterPro domains: - IPR051472: Type III Secretion System Stator and Flagellar Assembly (family) [9-216]
- IPR018035: Flagellar assembly protein FliH/Type III secretion system HrpE (domain) [85-205]
- IPR012842: Type 3 secretion system stator protein SctL/SctL2 (family) [30-198]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:0070887 (cellular response to chemical stimulus), GO:0010035 (response to inorganic substance), GO:0010038 (response to metal ion), GO:0071241 (cellular response to inorganic substance), GO:0071248 (cellular response to metal ion), GO:0010039 (response to iron ion), GO:0071281 (cellular response to iron ion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0033643 (host cell part), GO:0043657 (host cell), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0030430 (host cell cytoplasm)