Protein: Epididymis luminal protein 12 (Epididymis secretory sperm binding protein Li 53e) (V9HW83)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MSSSGTPDLPVLLTDLKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS
InterPro domains: - IPR016160: Aldehyde dehydrogenase, cysteine active site (conserved_site) [296-307]
- IPR015590: Aldehyde dehydrogenase domain (domain) [29-492]
- IPR016161: Aldehyde/histidinol dehydrogenase (homologous_superfamily) [13-496]
- IPR016162: Aldehyde dehydrogenase, N-terminal (homologous_superfamily) [34-492]
- IPR029510: Aldehyde dehydrogenase, glutamic acid active site (conserved_site) [268-275]
- IPR016163: Aldehyde dehydrogenase, C-terminal (homologous_superfamily) [274-463]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0042562 (hormone binding), GO:0005515 (protein binding), GO:0016491 (oxidoreductase activity), GO:0060589 (nucleoside-triphosphatase regulator activity), GO:0008047 (enzyme activator activity), GO:0016903 (oxidoreductase activity, acting on the aldehyde or oxo group of donors), GO:0030695 (GTPase regulator activity), GO:0005096 (GTPase activator activity), GO:0016620 (oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor), GO:0004030 (aldehyde dehydrogenase [NAD(P)+] activity), GO:0004029 (aldehyde dehydrogenase (NAD+) activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0098754 (detoxification), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0071704 (organic substance metabolic process), GO:1990748 (cellular detoxification), GO:0009056 (catabolic process), GO:1901700 (response to oxygen-containing compound), GO:1901575 (organic substance catabolic process), GO:0010033 (response to organic substance), GO:1901135 (carbohydrate derivative metabolic process), GO:0006081 (cellular aldehyde metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0009636 (response to toxic substance), GO:0110095 (cellular detoxification of aldehyde), GO:0097237 (cellular response to toxic substance), GO:1901136 (carbohydrate derivative catabolic process), GO:1901701 (cellular response to oxygen-containing compound), GO:0006040 (amino sugar metabolic process), GO:0110096 (cellular response to aldehyde), GO:0046348 (amino sugar catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0005576 (extracellular region), GO:0005615 (extracellular space), GO:0070062 (extracellular exosome), GO:0043227 (membrane-bounded organelle), GO:0043230 (extracellular organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:1903561 (extracellular vesicle)