Protein: DAB adaptor protein 2 (A0A8M1P9G4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm
Sequence: MSQSPEAETVTVVPAEPASTTESASVTITTAPVTRTSFWKERRKIPEKTDEFLLARFQGDGVRYKAKLIGVDDVQDARGDKMCQDSMMKLKGMAIAARSQGKHKQRIWINISLTGIKIVDEKTGVIEHEHVVNKISFIARDVTDNRAFGYVCGAEGQHQFFAIKTAQQAEPLVIDLKDLFQLIFNMKKKEQEAGQKGEGNGTENGGDALLAVDGNENPVKSVEQMNLFGDMSTPPDIHSPTPDSVLLLELSDLFDGNQVNQDNPFITNPSPLCNKPFDKSASSTSDLFPTLSSDPFSDDPFSPLNDQSDSVFSSNNESDFSSFLLNGPDSSEDPSPKSQQFNKLFDSQLSNESPNNQVQQLPISDLNGGTNSIFSQNPFLSISLNNPPIVNGLYSSDPPVLQAPLCNGSNKQLALFQTNPSTTVQNGGLTALCPPPQNLKPRCARRREKSPGNDLFGSGLFAPPAQNESQASNQNASIPADLFNSTPSSTINAFGSMSLGHAPGTAPVSWGQTPTMFPPQAGVQVTIPGPPRPFPQPSAFGGLSAPAWGQQGASPFGPPAGTQAWGQPGAAAPVGTWPAPGPVASPFQPNQFAPMMPPNAMMGMQQGAVAPPRPPPRPPVKEEPPVVKSAFTALDPLGEKESKSGKDMFKNFQMVKPQKPEPGPDPNTNGSFDQYFSNKVGLAQDAADHDDFEINQISANSNGTSKPASQLIPTMDAIPQAAGLIPAPATGLLDVAFSSNPVPAPTNPAPAAGTDLFDDTFGVNPFGAPLMNTSTPATQNAALADAFGDPFGGNPFA
InterPro domains: - IPR006020: PTB/PI domain (domain) [59-193]
- IPR048561: Disabled, phosphotyrosine-binding domain (domain) [47-196]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [46-203]
- IPR048559: Disabled homolog 1/2, sulfatide-binding motif (conserved_site) [54-72]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019904 (protein domain specific binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051234 (establishment of localization), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0090287 (regulation of cellular response to growth factor stimulus), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0001568 (blood vessel development), GO:0010646 (regulation of cell communication), GO:0048731 (system development), GO:0006810 (transport), GO:0009966 (regulation of signal transduction), GO:0007166 (cell surface receptor signaling pathway), GO:0035239 (tube morphogenesis), GO:0048514 (blood vessel morphogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0090092 (regulation of transmembrane receptor protein serine/threonine kinase signaling pathway), GO:0016192 (vesicle-mediated transport), GO:0030510 (regulation of BMP signaling pathway), GO:0007219 (Notch signaling pathway), GO:0006897 (endocytosis), GO:0006898 (receptor-mediated endocytosis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0070971 (endoplasmic reticulum exit site), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)