Protein: Interferon gamma 2 (B6UQB7)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Function: Not known
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Sequence: MDVLSRAVMCFCLMGWMTLGWSNAAQYTSINMKRNIDKLKVHYKISKDQLFNGNPVFPKDTFEDSEQRVLMSVVLDVYLSIFSQMLNQTGDQEVRERLDQVKGKVQETQKHYFLGRVPELRTHLQNLWAIKTSDTTVQGKALSEFITIYEKASKLAHEIHLKKDNRRKRRQAQRLKSHIM
InterPro domains: - IPR002069: Interferon gamma (family) [6-174]
- IPR009079: Four-helical cytokine-like, core (homologous_superfamily) [29-174]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0005126 (cytokine receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0002376 (immune system process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0009605 (response to external stimulus), GO:0051641 (cellular localization), GO:0023056 (positive regulation of signaling), GO:0042221 (response to chemical), GO:0048584 (positive regulation of response to stimulus), GO:0019222 (regulation of metabolic process), GO:0006955 (immune response), GO:0033036 (macromolecule localization), GO:0009892 (negative regulation of metabolic process), GO:0009607 (response to biotic stimulus), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0009893 (positive regulation of metabolic process), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0006950 (response to stress), GO:0051707 (response to other organism), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0043207 (response to external biotic stimulus), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0009966 (regulation of signal transduction), GO:0006952 (defense response), GO:0060255 (regulation of macromolecule metabolic process), GO:0010033 (response to organic substance), GO:0045087 (innate immune response), GO:0098542 (defense response to other organism), GO:0010646 (regulation of cell communication), GO:0031325 (positive regulation of cellular metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0070727 (cellular macromolecule localization), GO:0010647 (positive regulation of cell communication), GO:0007166 (cell surface receptor signaling pathway), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009615 (response to virus), GO:0034097 (response to cytokine), GO:0010562 (positive regulation of phosphorus metabolic process), GO:0051607 (defense response to virus), GO:0071310 (cellular response to organic substance), GO:0051246 (regulation of protein metabolic process), GO:0010628 (positive regulation of gene expression), GO:1904894 (positive regulation of receptor signaling pathway via STAT), GO:1904892 (regulation of receptor signaling pathway via STAT), GO:0010468 (regulation of gene expression), GO:0140546 (defense response to symbiont), GO:0140374 (antiviral innate immune response), GO:0051247 (positive regulation of protein metabolic process), GO:0034341 (response to type II interferon), GO:0008104 (protein localization), GO:0019221 (cytokine-mediated signaling pathway), GO:0010629 (negative regulation of gene expression), GO:0051174 (regulation of phosphorus metabolic process), GO:0033365 (protein localization to organelle), GO:0046427 (positive regulation of receptor signaling pathway via JAK-STAT), GO:0031399 (regulation of protein modification process), GO:0046425 (regulation of receptor signaling pathway via JAK-STAT), GO:0045937 (positive regulation of phosphate metabolic process), GO:0071345 (cellular response to cytokine stimulus), GO:0019220 (regulation of phosphate metabolic process), GO:0140888 (interferon-mediated signaling pathway), GO:0071346 (cellular response to type II interferon), GO:0031401 (positive regulation of protein modification process), GO:0042325 (regulation of phosphorylation), GO:0001932 (regulation of protein phosphorylation), GO:0042327 (positive regulation of phosphorylation), GO:0001934 (positive regulation of protein phosphorylation), GO:0050731 (positive regulation of peptidyl-tyrosine phosphorylation), GO:0042509 (regulation of tyrosine phosphorylation of STAT protein), GO:0050730 (regulation of peptidyl-tyrosine phosphorylation), GO:0042531 (positive regulation of tyrosine phosphorylation of STAT protein)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)