Protein: N-(5'-phosphoribosyl)anthranilate isomerase (PRAI) (EC 5.3.1.24) (P43073)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Sequence: MKVVKICGIKTVEAASVAIDNGANLLGCILVPNRARTIDLEVAKQIARMVKRDRNPPPKFAGGTSTQHFEQVAQWIIENGPFLVGVFRNQPKEEVFRIAREVGLDFIQLHGSEDKLEFLGTEFGLIPRYVVPDELDLLEEQSLSLTQCVSLPLLDSEVGGEGKLLDWTFIEKLPTKAILAGGLTPENLPTFDNILGYDVSGGVETNGVKDSLKIIKFIQKGHAQSS
InterPro domains: - IPR011060: Ribulose-phosphate binding barrel (homologous_superfamily) [3-219]
- IPR013785: Aldolase-type TIM barrel (homologous_superfamily) [2-224]
- IPR001240: N-(5'phosphoribosyl) anthranilate isomerase (PRAI) domain (domain) [1-224]
- IPR044643: N-(5'-phosphoribosyl)anthranilate isomerase family (family) [2-223]
Interaction partners: - Tryptophan synthase
- Multifunctional tryptophan biosynthesis protein
- Anthranilate phosphoribosyltransferase
- Imidazoleglycerol-phosphate dehydratase
- anthranilate synthase
- Orotidine 5'-phosphate decarboxylase
- 3-isopropylmalate dehydrogenase
- aminodeoxychorismate synthase
- Alpha-aminoadipate reductase
- Phosphoribosylaminoimidazole carboxylase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016853 (isomerase activity), GO:0016860 (intramolecular oxidoreductase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0046483 (heterocycle metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006066 (alcohol metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006766 (vitamin metabolic process), GO:0006790 (sulfur compound metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0006767 (water-soluble vitamin metabolic process), GO:0009110 (vitamin biosynthetic process), GO:0044272 (sulfur compound biosynthetic process), GO:0019438 (aromatic compound biosynthetic process), GO:0018130 (heterocycle biosynthetic process), GO:0034308 (primary alcohol metabolic process), GO:1901617 (organic hydroxy compound biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0042723 (thiamine-containing compound metabolic process), GO:0072527 (pyrimidine-containing compound metabolic process), GO:0046165 (alcohol biosynthetic process), GO:0042364 (water-soluble vitamin biosynthetic process), GO:0006772 (thiamine metabolic process), GO:0034309 (primary alcohol biosynthetic process), GO:0042724 (thiamine-containing compound biosynthetic process), GO:0072528 (pyrimidine-containing compound biosynthetic process), GO:0009228 (thiamine biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062039 (biofilm matrix), GO:0062040 (fungal biofilm matrix)