Protein: Nr4a1 protein (Q6GMG3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytosol. Nucleus
Sequence: MTCVQSQHGVQSYESSLFSSEFLNPDFTSRLAMDVTEQREQLSAPSLPSITSLVGGYVGEFDTYSCQIATGAASTCVGSTSGQLDSFKLDDLQVYGCYPGTFALSYLDETLSSSGGSNCFGSPASAPSPSTPGYQHMSAWDSTFGPCSPDEGCWGSEKPLNQAASFFTFGHVTADELSPLGQMQSQIPDQDPFSHTPQHGSPLPFSPLSLEQGSRDGSGLMDGHLSPKVRSPTGNEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKAVQDSVSVSSPVNIIASLVTAHIDSNPASANLDYSKYQESTSGLPEKEDANDIQQFYDLLTGSMDVIRKWAGSIPGFSAFCKEDQELLLESAFVELFILRLAYRSNPETDKLIFCNGVVLHRTQCVRSFGDWIDSIMEFSQSLHRLNLDISAFSCLATLVIITDRHGLKEPKRIEDFQNRLITCLRDHVSTSALEVGRPNSLSRLLSKLPELRTLCTQGLQRIFYLKLEDLVPPPPIVDKIFMDTLPF
InterPro domains: - IPR001723: Nuclear hormone receptor (family) [300-547]
- IPR013088: Zinc finger, NHR/GATA-type (homologous_superfamily) [231-332]
- IPR003070: Nuclear receptor subfamily 4 group A member 1-3 (family) [43-572]
- IPR000536: Nuclear hormone receptor, ligand-binding domain (domain) [336-571]
- IPR035500: Nuclear hormone receptor-like domain superfamily (homologous_superfamily) [310-574]
- IPR001628: Zinc finger, nuclear hormone receptor-type (domain) [236-311]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0060089 (molecular transducer activity), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0038023 (signaling receptor activity), GO:0097159 (organic cyclic compound binding), GO:0003676 (nucleic acid binding), GO:0004879 (nuclear receptor activity), GO:0098531 (ligand-activated transcription factor activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003677 (DNA binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding), GO:0000987 (cis-regulatory region sequence-specific DNA binding), GO:0000977 (RNA polymerase II transcription regulatory region sequence-specific DNA binding), GO:0000978 (RNA polymerase II cis-regulatory region sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0042592 (homeostatic process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0001776 (leukocyte homeostasis), GO:0048871 (multicellular organismal-level homeostasis), GO:0002262 (myeloid cell homeostasis), GO:0048468 (cell development), GO:0060322 (head development), GO:0030154 (cell differentiation), GO:0030900 (forebrain development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0001780 (neutrophil homeostasis), GO:0048872 (homeostasis of number of cells), GO:0007420 (brain development), GO:0022008 (neurogenesis), GO:0021872 (forebrain generation of neurons), GO:0007399 (nervous system development), GO:0007417 (central nervous system development), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0071542 (dopaminergic neuron differentiation), GO:0048699 (generation of neurons), GO:0021953 (central nervous system neuron differentiation), GO:0021879 (forebrain neuron differentiation), GO:0021954 (central nervous system neuron development), GO:0021884 (forebrain neuron development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)