Protein: T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (P47208)
Organism: Caenorhabditis elegans
Function: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
Subcellular location: Cytoplasm.
Sequence: MPPAVPAAAATARQSASGRERNFKDKDKPESVRNSNIVAAKAVADAVRTSLGPRGMDKMIQSGNGDVTITNDGATILNQMSVIHPTAKMLVELSKAQDIEAGDGTTTVVVMAGALLDAAQNLLSKGIHPTTISESFQSAAAEAEKILDEMSSPVDLSNDALLNKMATTSLNSKVVSQHSWLLAPMAVNAVKKIINSENDSNVNLKMIKIIKKMGDTVEESELIEGALIDQKTMGRGAPTRIEKAKIGLIQFQISPPKTDMENQVIITDYAQMDRALKEERQYLLEICKQIKAAGCNVLLIQKSILRDAVNELALHFLAKMKIMCIKDIEREDIEFYSRILGCRPVASVDHFNADALGYADLVEEIPTGGDGKVIKVTGVQNPGHAVSILLRGSNKLVLEEADRSIHDALCVIRCLVKKKALLPGGGAPEMEIAVKLRNLAQTQHGATQYCWRAFADALELIPYTLAENAGLSPIHTVTELRNNHANGNSSYGVNVRKGYVTDMVEEDVVQPLLVTASAIKQASECVRSILKIDDIVMAVR
InterPro domains: - IPR027410: TCP-1-like chaperonin intermediate domain superfamily (homologous_superfamily) [153-419]
- IPR012717: T-complex protein 1, delta subunit (family) [23-538]
- IPR053374: TCP-1 chaperonin-containing T-complex (family) [31-538]
- IPR027409: GroEL-like apical domain superfamily (homologous_superfamily) [219-392]
- IPR054827: Thermosome subunit alpha (family) [27-538]
- IPR002423: Chaperonin Cpn60/GroEL/TCP-1 family (family) [43-539]
- IPR002194: Chaperonin TCP-1, conserved site (conserved_site) [48-105]
- IPR027413: GroEL-like equatorial domain superfamily (homologous_superfamily) [25-538]
- IPR017998: Chaperone tailless complex polypeptide 1 (TCP-1) (family) [26-536]
Interaction partners: - T-complex protein 1 subunit alpha
- T-complex protein 1 subunit gamma
- T-complex protein 1 subunit epsilon
- T-complex protein 1 subunit zeta
- T-complex protein 1 subunit theta
- T-complex protein 1 subunit eta
- T-complex protein 1 subunit beta
- SET domain-containing protein
- Probable prefoldin subunit 5
- Putative peroxisomal biogenesis factor 19
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0006950 (response to stress), GO:0008340 (determination of adult lifespan), GO:0042221 (response to chemical), GO:0051649 (establishment of localization in cell), GO:1901700 (response to oxygen-containing compound), GO:0010035 (response to inorganic substance), GO:0046907 (intracellular transport), GO:0006979 (response to oxidative stress), GO:0010033 (response to organic substance), GO:0006810 (transport), GO:1902074 (response to salt), GO:0010038 (response to metal ion), GO:0051592 (response to calcium ion), GO:0051169 (nuclear transport), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0042542 (response to hydrogen peroxide), GO:0000302 (response to reactive oxygen species), GO:0006913 (nucleocytoplasmic transport), GO:0006611 (protein export from nucleus), GO:0051168 (nuclear export)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0140535 (intracellular protein-containing complex), GO:0005832 (chaperonin-containing T-complex), GO:0101031 (chaperone complex)