Protein: Lipocalin Can f 6.0101 (Allergen Can f 6) (allergen Can f 6.0101) (H2B3G5)
Organism: Canis lupus familiaris (Dog) (Canis familiaris)
Function: Not known
Subcellular location: Secreted {ECO:0000269|PubMed:23464525, ECO:0000305|PubMed:22515174}.
Sequence: MKLLLLCLGLILVHAHEEENDVVKGNFDISKISGDWYSILLASDIKEKIEENGSMRVFVKDIEVLSNSSLIFTMHTKVNGKCTKISLICNKTEKDGEYDVVHDGYNLFRIIETAYEDYIIFHLNNVNQEQEFQLMELYGRKPDVSPKVKEKFVRYCQGMEIPKENILDLTQVDRCLQARQSEAAQVSSAE
InterPro domains: - IPR012674: Calycin (homologous_superfamily) [14-190]
- IPR000566: Lipocalin/cytosolic fatty-acid binding domain (domain) [33-172]
- IPR022272: Lipocalin family conserved site (conserved_site) [26-39]
- IPR002345: Lipocalin (family) [4-175]
- IPR002971: Major urinary protein (family) [16-176]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:0043167 (ion binding), GO:0008289 (lipid binding), GO:0043168 (anion binding), GO:0043177 (organic acid binding), GO:0019840 (isoprenoid binding), GO:0031406 (carboxylic acid binding), GO:0005501 (retinoid binding), GO:0033293 (monocarboxylic acid binding), GO:0001972 (retinoic acid binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0023057 (negative regulation of signaling), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0048522 (positive regulation of cellular process), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0042127 (regulation of cell population proliferation), GO:0060548 (negative regulation of cell death), GO:0010941 (regulation of cell death), GO:0010646 (regulation of cell communication), GO:0080134 (regulation of response to stress), GO:0080135 (regulation of cellular response to stress), GO:0009966 (regulation of signal transduction), GO:0008284 (positive regulation of cell population proliferation), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:0070302 (regulation of stress-activated protein kinase signaling cascade), GO:1902532 (negative regulation of intracellular signal transduction), GO:1902531 (regulation of intracellular signal transduction), GO:0043408 (regulation of MAPK cascade), GO:0042981 (regulation of apoptotic process), GO:0070303 (negative regulation of stress-activated protein kinase signaling cascade), GO:0043066 (negative regulation of apoptotic process), GO:0032872 (regulation of stress-activated MAPK cascade), GO:0043409 (negative regulation of MAPK cascade), GO:0032873 (negative regulation of stress-activated MAPK cascade)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)