Protein: Probable E3 ubiquitin-protein ligase LUL4 (EC 2.3.2.27) (Probable RING-type E3 ubiquitin transferase LUL4) (Protein LOG2-LIKE UBIQUITIN LIGASE 4) (RING finger protein 208) (Q8LA32)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates (in vitro).
Sequence: MGISFSNNNRRRDNNNRRHLHHYPPPPPYYYLDPPPPPPPFPPHYDYNYSNYHLSPPLPPQPQINSCSYGHYHYHPQPPQYFTTAQPNWWGPMMRPAYYCPPQPQTQPPKPYLEQQNAKKVRNDVNVHRDTVRLEVDDLVPGHHLVSFVFDALFDGSFTITFFAKEEPNCTIIPQFPEVYSPTRFHFQKGPGQKFLQPSGTGTDLSFFVLDDLSKPLEEDVYPLVISAETIISPNSISEQSSVHKQVTQAVLEKDNDGSFKVKVVKQILWIEGVRYELRELYGSTTQGAASGLDESGSGTECVICMTEAKDTAVLPCRHLCMCSDCAKELRLQSNKCPICRQPIEELLEIKMNSSDEQH
InterPro domains: - IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [285-358]
- IPR045195: LOG2-like, modified RING finger, C3HC5-type (domain) [300-341]
- IPR045194: E3 ubiquitin-protein ligase MGRN1/RNF157-like (family) [1-354]
- IPR001841: Zinc finger, RING-type (domain) [302-341]
Interaction partners: - DNA-binding protein BIN4
- Zinc finger CCCH domain-containing protein 34
- Probable manganese-transporting ATPase PDR2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0042592 (homeostatic process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0010118 (stomatal movement), GO:0048878 (chemical homeostasis), GO:0019725 (cellular homeostasis), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0055082 (intracellular chemical homeostasis), GO:0009755 (hormone-mediated signaling pathway), GO:0070887 (cellular response to chemical stimulus), GO:0071495 (cellular response to endogenous stimulus), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0097305 (response to alcohol), GO:0032870 (cellular response to hormone stimulus), GO:0071310 (cellular response to organic substance), GO:0033993 (response to lipid), GO:0080144 (intracellular amino acid homeostasis), GO:0009737 (response to abscisic acid), GO:1901701 (cellular response to oxygen-containing compound), GO:0009738 (abscisic acid-activated signaling pathway), GO:0071215 (cellular response to abscisic acid stimulus), GO:0097306 (cellular response to alcohol), GO:0071396 (cellular response to lipid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)