Protein: GEO01805p1 (IP02725p) (SKP1-related B) (SKPB) (Q7KJ69)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MPIIRLESADKEIFDTDQEIAKCSETIRIAIEDLGDESDNSVLPLPNVNSLILKKVLHWATYHKDDPVVTEEVENKEKRTDDISSWDADFLKVDQGTLFELILAANYLNIQGLLDVTCKTVANMIKGKSPQAIRDTFAIQNDFLPQEEEQVRKENEWCEDK
InterPro domains: - IPR001232: S-phase kinase-associated protein 1-like (family) [1-110]
- IPR016073: SKP1 component, POZ domain (domain) [3-65]
- IPR011333: SKP1/BTB/POZ domain superfamily (homologous_superfamily) [2-161]
- IPR036296: SKP1-like, dimerisation domain superfamily (homologous_superfamily) [83-158]
- IPR016897: S-phase kinase-associated protein 1 (family) [1-161]
- IPR016072: SKP1 component, dimerisation (domain) [111-158]
Interaction partners: - S-phase kinase-associated protein 2
- Cullin homolog 1
- Cullin 6
- Supernumerary limbs, isoform B
- RING-box protein 1B
- Calcyclin-binding protein
- JmjC domain-containing histone demethylation protein 1
- F-box-like/WD repeat-containing protein ebi
- Transcriptional activator cubitus interruptus
- APC-like, isoform A
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0060090 (molecular adaptor activity), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0008152 (metabolic process), GO:0048519 (negative regulation of biological process), GO:0048856 (anatomical structure development), GO:0023057 (negative regulation of signaling), GO:2000241 (regulation of reproductive process), GO:0022402 (cell cycle process), GO:0006807 (nitrogen compound metabolic process), GO:0051241 (negative regulation of multicellular organismal process), GO:0071840 (cellular component organization or biogenesis), GO:0051239 (regulation of multicellular organismal process), GO:0009892 (negative regulation of metabolic process), GO:0050793 (regulation of developmental process), GO:0065008 (regulation of biological quality), GO:2000243 (positive regulation of reproductive process), GO:0002683 (negative regulation of immune system process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0021700 (developmental maturation), GO:0051093 (negative regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0048869 (cellular developmental process), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0007049 (cell cycle), GO:0002682 (regulation of immune system process), GO:0071704 (organic substance metabolic process), GO:0044237 (cellular metabolic process), GO:0009893 (positive regulation of metabolic process), GO:0045926 (negative regulation of growth), GO:0007017 (microtubule-based process), GO:0048585 (negative regulation of response to stimulus), GO:0040008 (regulation of growth), GO:0044238 (primary metabolic process), GO:0048522 (positive regulation of cellular process), GO:0050777 (negative regulation of immune response), GO:0009968 (negative regulation of signal transduction), GO:0090068 (positive regulation of cell cycle process), GO:0051129 (negative regulation of cellular component organization), GO:0060548 (negative regulation of cell death), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0051961 (negative regulation of nervous system development), GO:0080134 (regulation of response to stress), GO:0044786 (cell cycle DNA replication), GO:0048731 (system development), GO:0009966 (regulation of signal transduction), GO:0060255 (regulation of macromolecule metabolic process), GO:0032101 (regulation of response to external stimulus), GO:0002700 (regulation of production of molecular mediator of immune response), GO:0050803 (regulation of synapse structure or activity), GO:0061060 (negative regulation of peptidoglycan recognition protein signaling pathway), GO:0006725 (cellular aromatic compound metabolic process), GO:0044089 (positive regulation of cellular component biogenesis), GO:0044087 (regulation of cellular component biogenesis), GO:0045787 (positive regulation of cell cycle), GO:0071695 (anatomical structure maturation), GO:0031348 (negative regulation of defense response), GO:0051726 (regulation of cell cycle), GO:0009894 (regulation of catabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0002701 (negative regulation of production of molecular mediator of immune response), GO:0048469 (cell maturation), GO:0002697 (regulation of immune effector process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0016043 (cellular component organization), GO:0002698 (negative regulation of immune effector process), GO:0051128 (regulation of cellular component organization), GO:0044260 (cellular macromolecule metabolic process), GO:0007098 (centrosome cycle), GO:0010564 (regulation of cell cycle process), GO:0048638 (regulation of developmental growth), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0010648 (negative regulation of cell communication), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0080135 (regulation of cellular response to stress), GO:1900077 (negative regulation of cellular response to insulin stimulus), GO:0051298 (centrosome duplication), GO:0051130 (positive regulation of cellular component organization), GO:0000226 (microtubule cytoskeleton organization), GO:0034641 (cellular nitrogen compound metabolic process), GO:0031647 (regulation of protein stability), GO:0043170 (macromolecule metabolic process), GO:0002831 (regulation of response to biotic stimulus), GO:1900076 (regulation of cellular response to insulin stimulus), GO:2000026 (regulation of multicellular organismal development), GO:0050776 (regulation of immune response), GO:0010941 (regulation of cell death), GO:0006139 (nucleobase-containing compound metabolic process), GO:0010646 (regulation of cell communication), GO:0031325 (positive regulation of cellular metabolic process), GO:0048640 (negative regulation of developmental growth), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0031023 (microtubule organizing center organization), GO:0002832 (negative regulation of response to biotic stimulus), GO:0000278 (mitotic cell cycle), GO:0009896 (positive regulation of catabolic process), GO:0032102 (negative regulation of response to external stimulus), GO:0051964 (negative regulation of synapse assembly), GO:0031347 (regulation of defense response), GO:0007346 (regulation of mitotic cell cycle), GO:0050807 (regulation of synapse organization), GO:0051246 (regulation of protein metabolic process), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:0070302 (regulation of stress-activated protein kinase signaling cascade), GO:0042023 (DNA endoreduplication), GO:1900424 (regulation of defense response to bacterium), GO:0010468 (regulation of gene expression), GO:0048666 (neuron development), GO:0007399 (nervous system development), GO:0090304 (nucleic acid metabolic process), GO:0046627 (negative regulation of insulin receptor signaling pathway), GO:1900425 (negative regulation of defense response to bacterium), GO:0006259 (DNA metabolic process), GO:0030178 (negative regulation of Wnt signaling pathway), GO:0008582 (regulation of synaptic assembly at neuromuscular junction), GO:0002920 (regulation of humoral immune response), GO:0008348 (negative regulation of antimicrobial humoral response), GO:0010629 (negative regulation of gene expression), GO:0042551 (neuron maturation), GO:0002784 (regulation of antimicrobial peptide production), GO:0046626 (regulation of insulin receptor signaling pathway), GO:0045088 (regulation of innate immune response), GO:0042176 (regulation of protein catabolic process), GO:1901888 (regulation of cell junction assembly), GO:0002921 (negative regulation of humoral immune response), GO:0062207 (regulation of pattern recognition receptor signaling pathway), GO:0030111 (regulation of Wnt signaling pathway), GO:1902532 (negative regulation of intracellular signal transduction), GO:0051960 (regulation of nervous system development), GO:0045931 (positive regulation of mitotic cell cycle), GO:1901889 (negative regulation of cell junction assembly), GO:1905809 (negative regulation of synapse organization), GO:0022008 (neurogenesis), GO:0002759 (regulation of antimicrobial humoral response), GO:0045886 (negative regulation of synaptic assembly at neuromuscular junction), GO:0051247 (positive regulation of protein metabolic process), GO:0033043 (regulation of organelle organization), GO:0045732 (positive regulation of protein catabolic process), GO:0031331 (positive regulation of cellular catabolic process), GO:0031329 (regulation of cellular catabolic process), GO:0006996 (organelle organization), GO:0010638 (positive regulation of organelle organization), GO:0030182 (neuron differentiation), GO:1902531 (regulation of intracellular signal transduction), GO:0042981 (regulation of apoptotic process), GO:0030162 (regulation of proteolysis), GO:1904397 (negative regulation of neuromuscular junction development), GO:1904396 (regulation of neuromuscular junction development), GO:0007010 (cytoskeleton organization), GO:0051963 (regulation of synapse assembly), GO:0006260 (DNA replication), GO:0070303 (negative regulation of stress-activated protein kinase signaling cascade), GO:0048699 (generation of neurons), GO:0016322 (neuron remodeling), GO:0090090 (negative regulation of canonical Wnt signaling pathway), GO:0033044 (regulation of chromosome organization), GO:0060828 (regulation of canonical Wnt signaling pathway), GO:2000058 (regulation of ubiquitin-dependent protein catabolic process), GO:0032872 (regulation of stress-activated MAPK cascade), GO:0035330 (regulation of hippo signaling), GO:0043409 (negative regulation of MAPK cascade), GO:0043408 (regulation of MAPK cascade), GO:0035331 (negative regulation of hippo signaling), GO:0061058 (regulation of peptidoglycan recognition protein signaling pathway), GO:0043066 (negative regulation of apoptotic process), GO:0051276 (chromosome organization), GO:2001252 (positive regulation of chromosome organization), GO:0045862 (positive regulation of proteolysis), GO:1901800 (positive regulation of proteasomal protein catabolic process), GO:2000060 (positive regulation of ubiquitin-dependent protein catabolic process), GO:0061136 (regulation of proteasomal protein catabolic process), GO:0006261 (DNA-templated DNA replication), GO:0032436 (positive regulation of proteasomal ubiquitin-dependent protein catabolic process), GO:0032873 (negative regulation of stress-activated MAPK cascade), GO:0046328 (regulation of JNK cascade), GO:1903052 (positive regulation of proteolysis involved in protein catabolic process), GO:0032434 (regulation of proteasomal ubiquitin-dependent protein catabolic process), GO:1903050 (regulation of proteolysis involved in protein catabolic process), GO:0030261 (chromosome condensation), GO:0046329 (negative regulation of JNK cascade)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005829 (cytosol), GO:1902494 (catalytic complex), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0140535 (intracellular protein-containing complex), GO:1990234 (transferase complex), GO:0000151 (ubiquitin ligase complex), GO:0031461 (cullin-RING ubiquitin ligase complex), GO:0019005 (SCF ubiquitin ligase complex)