Protein: Phospholipase (EC 3.1.4.4) (A4UZ54)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00037868}; Lipid-anchor {ECO:0000256|ARBA:ARBA00037868}.
Sequence: MADAGTVGGALPPYALTNSDEEHGSGEEDASEENSNNEEGEGVFRDCTDEAVVEHHNRCLPEFQFSLVDSEYDETLAFPDSVTILSNVGDKPVLVERKETDDDEEEFDDEENNSVVLRHEIPFTSIYGPSVKFNSFQRKVFIPGREIHVRIVDTERSVTTHLLNPNLYTIELTHGPFKWTIKRRYKHFNSLHQQLSFFRTSLNIPFPSRSHKEKRTTLKATAREMADESTLKDLPSHTKVKQTSTPLRAEGRSSKIAGSNANNAMAMISPNHSSILAGLTPRRIQKKRKKKKKRKLPRFPNRPESLVTVENLSVRIKQLEDYLYNLLNISLYRSHHETGKEGVILKRTGSTRPGQAGCNFFGCFQKNCCVRCNYFCSDVVCGTWRNRWFFVKETCFGYIRPTDGSIRAVILFDQGFDVSTGIYQTGMRKGLQVLTNNRHIVLKCWTRRKCKEWMQYLKNTANSYARDFTLPNPHMSFAPMRANTHATWYVDGAQYMSAVADGLEAALEEIYIADWWLSPEIYMKRPALDGDYWRLDKILLRKAEQGVRVFVLLYKEVEMALGINSYYSKSTLAKHENIKVMRHPDHARGGILLWAHHEKIVVIDQTYAFMGGIDLCYGRWDDHHHRLTDLGSISTSSFSGSTRRTPSLYFTKDDTDSAFGSRKSSRNAHYDTSAKERPPSPPPDEPNTSIELKTLKPGDRLLIPSTLVSSPGETPAESGIALEGMKLNTPEMERKNVLDRLKNNAMKGARMGKDFMHRLTATETEEKSAEVYTIESEEATDHEVNLNMASGGQEVAITTSSTQILSEFCGQAKYWFGKDYSNFILKDWMNLNSPFVDIIDRTTTPRMPWHDVGLCVVGTSARDVARHFIQRWNAMKLEKLRDNTRFPYLMPKSYHQVRLNPNIQQNRQQRVTCQLLRSVSAWSCGFIEADLVEQSIHDAYIQTITKAQHYVYIENQFFITMQLGMGVPGAYNNVRNQIGETLFKRIVRAHKERKPFRVYVIMPLLPGFEGDVGGSTGIAVRAITHWNYASISRGRTSILTRLQEAGIANPENYISFHSLRNHSFLNNTPITELIYVHSKLLIADDRVVICGSANINDRSMIGKRDSEIAAILMDEEFEDGRMNGKKYPSGVFAGRLRKYLFKEHLGLLESEGSSRSDLDINDPVCEKFWHGTWRRISMQNTEIYDEVFKCIPTDFVKTFASLRKYQEEPPLAKTAPDLAANRANDIQGYLVDLPLEFLNKEVLTPPGTSKEGLIPTSVWT
InterPro domains: - IPR036871: PX domain superfamily (homologous_superfamily) [134-248]
- IPR001683: Phox homology (domain) [146-355]
- IPR015679: Phospholipase D family (family) [395-1238]
- IPR001736: Phospholipase D/Transphosphatidylase (domain) [592-1099]
- IPR016555: Phospholipase D, eukaryotic type (family) [1-1260]
- IPR025202: Phospholipase D-like domain (domain) [941-1117]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [334-469]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0016298 (lipase activity), GO:0042578 (phosphoric ester hydrolase activity), GO:0008081 (phosphoric diester hydrolase activity), GO:0004620 (phospholipase activity), GO:0004630 (phospholipase D activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0051606 (detection of stimulus), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0051050 (positive regulation of transport), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0048522 (positive regulation of cellular process), GO:0009581 (detection of external stimulus), GO:0051049 (regulation of transport), GO:0048598 (embryonic morphogenesis), GO:0007349 (cellularization), GO:0009314 (response to radiation), GO:0016043 (cellular component organization), GO:0009582 (detection of abiotic stimulus), GO:0060627 (regulation of vesicle-mediated transport), GO:0051130 (positive regulation of cellular component organization), GO:0009790 (embryo development), GO:0051128 (regulation of cellular component organization), GO:0007602 (phototransduction), GO:0031340 (positive regulation of vesicle fusion), GO:0009416 (response to light stimulus), GO:0031338 (regulation of vesicle fusion), GO:0010256 (endomembrane system organization), GO:0007369 (gastrulation), GO:0033043 (regulation of organelle organization), GO:0006996 (organelle organization), GO:0010638 (positive regulation of organelle organization), GO:0009583 (detection of light stimulus), GO:0007030 (Golgi organization), GO:0001703 (gastrulation with mouth forming first), GO:0010004 (gastrulation involving germ band extension)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle)