wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Chromodomain helicase DNA binding protein 3 (B0QZH8)
Organism: Mus musculus (Mouse)
Function: Not known
Sequence: LKIKLGLLGGKRKKAGSCAFQSEEGHEPEAEESDLDSGSVHSASGWPDGPVRAKKLKRGRPGRKKKKVTGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEKEGVQWEAKEEEEEYE
InterPro domains: - IPR011011: Zinc finger, FYVE/PHD-type (homologous_superfamily) [51-128]
- IPR019787: Zinc finger, PHD-finger (domain) [82-129]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [73-132]
- IPR019786: Zinc finger, PHD-type, conserved site (conserved_site) [85-126]
- IPR001965: Zinc finger, PHD-type (domain) [84-127]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006325 (chromatin organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:1902494 (catalytic complex), GO:0140513 (nuclear protein-containing complex), GO:0005667 (transcription regulator complex), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0070603 (SWI/SNF superfamily-type complex), GO:0000118 (histone deacetylase complex), GO:0043229 (intracellular organelle), GO:1904949 (ATPase complex), GO:0043227 (membrane-bounded organelle), GO:0016581 (NuRD complex), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0090545 (CHD-type complex), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005694 (chromosome), GO:0005634 (nucleus)
Protein: Glial fibrillary acidic protein (F1RR02)
Organism: Sus scrofa (Pig)
Function: Not known
Sequence: MERRRVTSAARRSYVSSLETVGGGRRLGPGPRLSLARMPPPLPARVDFSLAGALNTGFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAELRELRLRLDQLTANGARLEVERDNLAQDLGTLRQKLQDETNLRLEAENNLATYRQEADEATLARLDLERKIESLEEEIRFLRKIHDEEVRELQEQLAQQQVHVEMDVTKPDLTAALREIRTQYEAVATSNMQEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQALTCDVESLRGTNESLERQMREQEERHAREAASYQEALTRLEEEGQSLKDEMARHLQEYQELLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRGGKSTKEGEGHKVTRHLKSLTIQVIPIQAHQIVNGAPPALETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKESKQEHKDVV
InterPro domains: - IPR050405: Intermediate filament structural protein (family) [8-461]
- IPR006821: Intermediate filament head, DNA-binding domain (domain) [7-62]
- IPR018039: Intermediate filament protein, conserved site (conserved_site) [359-367]
- IPR039008: Intermediate filament, rod domain (domain) [64-373]
Interaction partners: - Aquaporin-4
- Neurotrophic factor BDNF precursor form
- Oligodendrocyte transcription factor 2
- Microtubule-associated protein
- Paired box 6.
- Caspase-3
- Lactoperoxidase
- Myelin basic protein
- Doublecortin
- Interleukin-6
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0045103 (intermediate filament-based process), GO:0045104 (intermediate filament cytoskeleton organization), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0007010 (cytoskeleton organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0099513 (polymeric cytoskeletal fiber), GO:0005882 (intermediate filament), GO:0045111 (intermediate filament cytoskeleton)
Protein: ADD1 protein (Q96D30)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004413}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Sequence: MNGDSRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSMILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMSLGMVTPVNDLRGSDSIAYDKGEKLLRCKLAAFYRLADLFGWSQLIYNHITTRVNSEQEHFLIVPFGLLYSEVTASSLVKINLQGDIVDRGSTNLGVNQAGFTLHSAIYAARPDVKCVVHIHTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILRNHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLNPEKYKAKSRSPGSPVGEGTGSPPKWQIGEQEFEALMRMLDNLGYRTSSSGRRQDG
InterPro domains: - IPR036409: Class II aldolase/adducin N-terminal domain superfamily (homologous_superfamily) [135-391]
- IPR001303: Class II aldolase/adducin N-terminal (domain) [147-329]
- IPR051017: Aldolase class II Adducin subfamily (family) [1-393]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006520 (amino acid metabolic process), GO:0043603 (amide metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006082 (organic acid metabolic process), GO:0006536 (glutamate metabolic process), GO:0043436 (oxoacid metabolic process), GO:1901605 (alpha-amino acid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0009064 (glutamine family amino acid metabolic process), GO:0043648 (dicarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015629 (actin cytoskeleton)
Protein: Fms related receptor tyrosine kinase 1 (F1RSU5)
Organism: Sus scrofa (Pig)
Function: Not known
Sequence: MNSDLLVDSDDFYKQPITMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLARDIYKNPDYVRKGDTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKEGVRMRAPEYATPEIYQIMLDCWHKDPKERPRFVELVEKLGDLLQANVQQDGKDYIPLNAILTSNSGFTYSTPAFSEDFFKEDISAPKFNSASSDNVRYVNAFNLISLERIKTFEELSPNATTSVLNDYQMDNGSLLACPLLKRFTWTESKPKASLKIDLRVTSKSKESGLCDLNRPTFCHSSCGHLSTGQRRFTYDHSELERKISCCSPPPDYNSVVLYSSPPV
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [14-175]
- IPR050122: Receptor Tyrosine Kinase (family) [14-188]
- IPR001245: Serine-threonine/tyrosine-protein kinase, catalytic domain (domain) [14-177]
- IPR000719: Protein kinase domain (domain) [1-181]
- IPR008266: Tyrosine-protein kinase, active site (active_site) [41-53]
- IPR020635: Tyrosine-protein kinase, catalytic domain (domain) [1-177]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0050793 (regulation of developmental process), GO:0051093 (negative regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0050794 (regulation of cellular process), GO:0045595 (regulation of cell differentiation), GO:0045596 (negative regulation of cell differentiation), GO:0010453 (regulation of cell fate commitment), GO:0009996 (negative regulation of cell fate specification), GO:0042659 (regulation of cell fate specification), GO:0010454 (negative regulation of cell fate commitment)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Fe2+/Zn2+ uptake regulation proteins (Q8NNC4)
Organism: Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Sequence: MGINRISQGSAPKLGVRSTRQRKAVIDVLEEIDNFASAKEIHHELSTREHNVGLTTVYRTLQSLADIGAVDVLTVTGGETLYRQCHDEGHHHHLVCTNCGRTVEIDGGPVETWAQEIATKNGFALSSHEAEIFGLCADCKEKVT
InterPro domains: - IPR043135: Ferric-uptake regulator, C-terminal domain (homologous_superfamily) [92-143]
- IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [13-138]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [9-91]
- IPR002481: Ferric-uptake regulator (family) [13-142]
Interaction partners: - DNA-directed RNA polymerase subunit alpha
- ABC-type transporter, permease components
- Predicted transcriptional regulators
- ABC-type transporter, ATPase component
- ABC-type transporter, permease components
- ABC-type transporter, periplasmic component
- ABC-type transporter, periplasmic component
- GTPases
- Diphtheria toxin repressor
- DNA-directed RNA polymerase subunit omega
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0032993 (protein-DNA complex)
Protein: WAS/WASL-interacting protein family member 2 (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein) (WIP-related protein) (Q8TF74)
Organism: Homo sapiens (Human)
Function: Plays an active role in the formation of cell surface protrusions downstream of activated PDGFB receptors. Plays an important role in actin-microspike formation through cooperation with WASL. May cooperate with WASP and WASL to induce mobilization and reorganization of the actin filament system.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11829459, ECO:0000269|PubMed:12213210}. Note=Localized to stress fibers and bundles of actin filaments.
Sequence: MPIPPPPPPPPGPPPPPTFHQANTEQPKLSRDEQRGRGALLQDICKGTKLKKVTNINDRSAPILEKPKGSSGGYGSGGAALQPKGGLFQGGVLKLRPVGAKDGSENLAGKPALQIPSSRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPPPLRNGHRDSITTVRSFLDDFESKYSFHPVEDFPAPEEYKHFQRIYPSKTNRAARGAPPLPPILR
InterPro domains: - IPR003124: WH2 domain (domain) [36-61]
Interaction partners: - Actin nucleation-promoting factor WASL
- Actin nucleation-promoting factor WAS
- Cytoplasmic protein NCK2
- SH2/SH3 adapter protein NCK1
- WAS/WASL-interacting protein family member 3
- WAS/WASL-interacting protein family member 1
- Growth factor receptor-bound protein 2
- Cell division control protein 6 homolog
- Actin-binding protein WASF1
- Unconventional myosin-If
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044183 (protein folding chaperone), GO:0005515 (protein binding), GO:0005522 (profilin binding), GO:0019904 (protein domain specific binding), GO:0008092 (cytoskeletal protein binding), GO:0017124 (SH3 domain binding), GO:0003779 (actin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0030029 (actin filament-based process), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0030036 (actin cytoskeleton organization), GO:0043933 (protein-containing complex organization), GO:0006996 (organelle organization), GO:0097435 (supramolecular fiber organization), GO:0007015 (actin filament organization), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly), GO:0007010 (cytoskeleton organization), GO:0008154 (actin polymerization or depolymerization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: UPF0716 protein FxsA (Suppressor of F exclusion of phage T7) (P37147)
Organism: Escherichia coli (strain K12)
Function: Overexpression alleviates the exclusion of phage T7 in cells harboring the F plasmid.
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Sequence: MRWLPFIAIFLYVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGMSLVRNQGFKNFVLMQQKMAAGENPAAEMIKSVSLIIAGLLLLLPGFFTDFLGLLLLLPPVQKHLTVKLMPHLRFSRMPGGGFSAGTGGGNTFDGEYQRKDDERDRLDHKDDRQD
InterPro domains: - IPR007313: FxsA cytoplasmic membrane protein (family) [1-155]
Interaction partners: - Small heat shock protein IbpA
- Chaperedoxin
- UPF0250 protein YbeD
- ATP-dependent protease subunit HslV
- UPF0283 membrane protein YcjF
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051641 (cellular localization), GO:0055085 (transmembrane transport), GO:0042221 (response to chemical), GO:0051234 (establishment of localization), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0033036 (macromolecule localization), GO:0046907 (intracellular transport), GO:0071806 (protein transmembrane transport), GO:0006810 (transport), GO:0046677 (response to antibiotic), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0051668 (localization within membrane), GO:0045184 (establishment of protein localization), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0043952 (protein transport by the Sec complex), GO:0015031 (protein transport), GO:0072594 (establishment of protein localization to organelle), GO:0071702 (organic substance transport), GO:0065002 (intracellular protein transmembrane transport), GO:0008104 (protein localization), GO:0090150 (establishment of protein localization to membrane), GO:0072657 (protein localization to membrane), GO:0033365 (protein localization to organelle), GO:0006612 (protein targeting to membrane), GO:0006605 (protein targeting), GO:0072599 (establishment of protein localization to endoplasmic reticulum), GO:0051205 (protein insertion into membrane), GO:0070972 (protein localization to endoplasmic reticulum), GO:0006613 (cotranslational protein targeting to membrane), GO:0045047 (protein targeting to ER), GO:0006614 (SRP-dependent cotranslational protein targeting to membrane)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Pteridine reductase 1 (EC 1.5.1.33) (H region methotrexate resistance protein) (Q01782)
Organism: Leishmania major
Function: Exhibits a NADPH-dependent biopterin reductase activity. Has good activity with folate and significant activity with dihydrofolate and dihydrobiopterin, but not with quinonoid dihydrobiopterin. Confers resistance to methotrexate (MTX).
Sequence: MTAPTVPVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRFAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVDDMPPAVWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLTRA
InterPro domains: - IPR014058: Pteridine reductase (family) [7-288]
- IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [8-285]
- IPR020904: Short-chain dehydrogenase/reductase, conserved site (conserved_site) [181-209]
- IPR002347: Short-chain dehydrogenase/reductase SDR (family) [8-284]
Interaction partners: - Bifunctional dihydrofolate reductase-thymidylate synthase
- Putative 3-oxoacyl-ACP reductase
- Dihydropteridine reductase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0042180 (cellular ketone metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0046483 (heterocycle metabolic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0042181 (ketone biosynthetic process), GO:0006720 (isoprenoid metabolic process), GO:0008299 (isoprenoid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0018130 (heterocycle biosynthetic process), GO:0006721 (terpenoid metabolic process), GO:0016114 (terpenoid biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Chromosome 11 open reading frame 54 (E9PIP1)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MACAEFSFHVPSLEELAGVMQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLVNQKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPVIQTESEHKPPVNGSYFAHVNPADGGCLLEKYSEKCHDFQCALLANLFASEGQPGKVI
InterPro domains: - IPR015021: Ester hydrolase C11orf54, Domain of unknown function DUF1907 (domain) [1-171]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023056 (positive regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010647 (positive regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0010646 (regulation of cell communication), GO:0045745 (positive regulation of G protein-coupled receptor signaling pathway), GO:0008277 (regulation of G protein-coupled receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)