Protein: 14-3-3-like protein GF14 upsilon (General regulatory factor 5) (P42645)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes. May be involved in cell cycle regulation by binding to soluble EDE1 and sequestering it in an inactive form during the early stages of mitosis.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21558460}. Nucleus {ECO:0000269|PubMed:21558460}. Note=Not associated with microtubules (PubMed:21558460). Translocates from the cytosol to the nucleus when phosphorylated (By similarity). {ECO:0000250|UniProtKB:P48349, ECO:0000269|PubMed:21558460}.
Sequence: MSSDSSREENVYLAKLAEQAERYEEMVEFMEKVAKTVETEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEDSRGNSDHVSIIKDYRGKIETELSKICDGILNLLEAHLIPAASLAESKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLVAYKSAQDIALADLAPTHPIRLGLALNFSVFYYEILNSSDRACSLAKQAFDEAISELDTLGEESYKDSTLIMQLLRDNLTLWTSDLNDEAGDDIKEAPKEVQKVDEQAQPPPSQ
InterPro domains: - IPR023409: 14-3-3 protein, conserved site (conserved_site) [47-238]
- IPR036815: 14-3-3 domain superfamily (homologous_superfamily) [1-250]
- IPR000308: 14-3-3 protein (family) [1-249]
- IPR023410: 14-3-3 domain (domain) [7-250]
Interaction partners: - Ubiquitin-ribosomal protein eS31z fusion protein
- Dual specificity phosphatase Cdc25
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0050794 (regulation of cellular process), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0007165 (signal transduction), GO:0007154 (cell communication), GO:0071495 (cellular response to endogenous stimulus), GO:1901700 (response to oxygen-containing compound), GO:0009755 (hormone-mediated signaling pathway), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0009725 (response to hormone), GO:0048545 (response to steroid hormone), GO:0009741 (response to brassinosteroid), GO:0032870 (cellular response to hormone stimulus), GO:0014070 (response to organic cyclic compound), GO:0071310 (cellular response to organic substance), GO:0033993 (response to lipid), GO:1901701 (cellular response to oxygen-containing compound), GO:0043401 (steroid hormone mediated signaling pathway), GO:0071367 (cellular response to brassinosteroid stimulus), GO:0071383 (cellular response to steroid hormone stimulus), GO:0071396 (cellular response to lipid), GO:0071407 (cellular response to organic cyclic compound), GO:0009742 (brassinosteroid mediated signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0005829 (cytosol), GO:0055044 (symplast), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0012505 (endomembrane system), GO:0030312 (external encapsulating structure), GO:0005794 (Golgi apparatus), GO:0005773 (vacuole), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0009506 (plasmodesma), GO:0070161 (anchoring junction), GO:0043227 (membrane-bounded organelle), GO:0005618 (cell wall), GO:0005886 (plasma membrane), GO:0009536 (plastid), GO:0000325 (plant-type vacuole), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle), GO:0009505 (plant-type cell wall), GO:0005911 (cell-cell junction), GO:0005634 (nucleus)