Protein: Sterol 3-beta-glucosyltransferase (Q5A950)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Sterol glycosyltransferase responsible for the glycosylation of ergosterol to form ergosterol-glucoside
Subcellular location: Cytoplasm. Membrane; Peripheral membrane protein
Sequence: MSFYKKVTRGLATPLQGSINLFSGSPNVSGDEGTDADNENPEHRTTYHSLSGRVNHDDDDEDVAKLEDIVGFFTGLLNTTTVCAGLGSLNNLKKHYLDEFIKKSALNPLRPQNYGPETSSKLNNNSIEELLNNGDTSLEKVRKMSLYDFDEHTSDSEEEDSADKEEESIAENLKPGKSGKARNHPRDSRTTATLITTQITRTKTATTATPTPTPTSSVDTDVTDVTEPIGKVTTKIPEEQLQGLNPLQKSVVKNLDPHHVREGVLIKVKNSETPLKNDRQELLEKIQLRLKIADKLQRVFDLSDEDTFCGNYSAWLIKDVLLQGHVYLTKDALLYFAFLPKRFSLENSSEVLDEDNSSSIVYSGNLGLKSAKYGEVVLNTVLQHRYWAVLRAETLSIYSSSTNLYFPVLVIDIKKCLYTEIIDKEKLNREAISPVNRGTYSPNGGLSGTATPRASTLENTASELNSMLSGDSYSPTEDNVETTASTVWFKLVTKKKTYKFSCDSSFSARQWCNNITKLIFQHNNANSNGEVLIKIPISKIAEYNKRALFSEEEEEDRTLDVTMNDIPLNVTIKYLGDNDNERKRDKLKRKYKGEEPTIEEVHFLFPKSGVEFFETFDKLVNPVVSDNDNQSSKSSITSTNFSEKAISTLSKSPNHLVQTVLDFNKPVDDDISAFKKFGTTITSPTRIFKATITSPEMTSIDETSLRDSFDSDRLHLPRDMSERALKNLEVSFVTSLKKLEDASKRYEKPHMEHSQTNLASILSDPSEVKKESKTAISKSIKALYSVGTHWSATPNHYFELGKYYVNKVQDRDSSQRNFQSHFSTNSKLLASYYGHLLRTVPVYGKIYVSETDVCFRSLLPGVSTKMVLPMTDIEEVRASRGSRLTYHGLRLIVRGSEELDLEFGSSKSRDDFQKVVLSVLERLHSKEGFRPEPYQWGSNFEVELYKTRMEYSDSENREIQQYDNSIDIKFAEKKIEMARVRMFEDRLMAASGLDVPIILEDSPFFKTELRPSTSYNITLLTIGSRGDVQPYIALGKGLVKEGHNVTIATHAEFGDWIKTFGLGFKEIAGDPAELMSFMVTHNSMSVGFLKNAQQKFRSWISKLLTTSWEACQGSDILIESPSAMSGIHIAEALGIPYFRAFTMPWTRTRAYPHAFFVPEQKKGGSYNYLTHVLFENIFWKGISGQVNKWRVEELDLPKTNLYRLQQTRVPFLYNVSPAILPPSVDFPDWIKVTGYWFLDEGSGDYKPPEELVQFMKKASRDKKKIVYIGFGSIVVKDAKSLTKAVVSAVRRADVRCILNKGWSDRLDNKDKNEIEIELPPEIYNSGTIPHDWLFPRIDAAVHHGGSGTTGATMRAGIPTIIKPFFGDQFFYATRIEDLGAGIALKKLTAKTLGDALVKATHDLKIIDKAKRVSQQIKHEHGVLSAIESIYSELEYSRNLILIKDIHNQNYKRHHPVPSGVQTPAYDTDSDDYDDDEDDDESDKDDEEEEEENSYDGYDGNGVNNSPSQNSSN
InterPro domains: - IPR004182: GRAM domain (domain) [294-924]
- IPR004276: Glycosyltransferase family 28, N-terminal domain (domain) [1017-1152]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [351-922]
- IPR001849: Pleckstrin homology domain (domain) [359-522]
- IPR050426: Glycosyltransferase 28 (family) [821-1462]
- IPR002213: UDP-glucuronosyl/UDP-glucosyltransferase (family) [1015-1429]
- IPR048065: Autophagy-related protein 26, PH-GRAM domain 2 (domain) [825-917]
- IPR010610: Erythromycin biosynthesis protein CIII-like, C-terminal domain (domain) [1308-1414]
Interaction partners: - Sorting nexin-4
- Autophagy-related protein 11
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060090 (molecular adaptor activity), GO:0030674 (protein-macromolecule adaptor activity), GO:0043495 (protein-membrane adaptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0030447 (filamentous growth), GO:0006950 (response to stress), GO:0009607 (response to biotic stimulus), GO:0007154 (cell communication), GO:0009991 (response to extracellular stimulus), GO:0031668 (cellular response to extracellular stimulus), GO:0044182 (filamentous growth of a population of unicellular organisms), GO:0036180 (filamentous growth of a population of unicellular organisms in response to biotic stimulus), GO:0042594 (response to starvation), GO:0071496 (cellular response to external stimulus), GO:0033554 (cellular response to stress), GO:0036170 (filamentous growth of a population of unicellular organisms in response to starvation), GO:0009267 (cellular response to starvation), GO:0031669 (cellular response to nutrient levels), GO:0031667 (response to nutrient levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)