Protein: Translation initiation factor eIF4G (A0A1D8PI73)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Cytoplasm
Sequence: MSDNTTSNQSSTGDSKSTPGAVPSSTDGSSSAPIGNSVNSVDQTSVSTDKQHGNQNVPQSSGAYSGQNYNANYQGYGNNPNYNNNYNNNNNNNPNYYHKNQYNKNYTGGNSGGSGGRQNNYNNNANQNNNQRYNNNKKQYNNQKMNHHHHNQQQPQQQYVNYPYNTAAAAASQMYGYYMGGYQPVYGLPLQYGGIPATPGQQYPGQVASPVVPTVQPQQISTPPTPKIRLTTKDGKPVDLDEKKRKTASSTPVASPQPARATTVSSEKDKTPSSSATPATENKPAGISAAEEFKRKIRERAAAAAAAASKGKETKEETKEETTATETKKETEETPIAKESSSTVDQPSVVPPQESHKDIVETPKPEVTETSVEATKELPASEETKEVLSSETNDTTAVEKPKVEEKPVEVNDKVESQIELQSPSVEGDSESIVENEDEEESTISEKGEPQTETETETETQTEPEPESEPTPTANAPEFTISQFLERLKIATPIDDILATKYPETIQGVDGSKQISGKKYRYDPQFLIQFRDVISYTIDPTFKAHLESLDIHPNAMKRSGSTRDASSRGGLPNKFTGGLPARFNGPGGKGGGQFDGGRQNSRSGSKRGGGRGASSRDKSTRKGTPSKRGGRGGDRSEMRERGGAGAGAGAGAGGENDGNNQGDGKPVEEVKPLEKSANRWVPKSRMQAKKETKVAEDGTILLEPEDIEKKTKSLLNKLTLEMFTAISDEIIALTNQSKHEKDAATIKQIISLTFAKACDEPHWSEMYAKLCAKMCTSVSNDITDESITLKDGTHASGGVLARRLLLATCQKEYEKGWTDKLPTNPDGSPLEPEMMSDEYYAMAAAKRRGLGLVKFIGHLYNLNMLNDHVIYVCLKDQTKNTVDPSDDSLENLTQLIQTVGPKLDSNERTRTMLKIVFDYIEKVLEGVKLTSRIKFMLMDLQDLREAKWVSLKGDAGPKTIEEIHRDAEIKKMEEERAKNEKKRKQHQLGGGVGGGSDSRSNSSRGGSNWNNNNNNNNNNNNNQSSNGPFMKKSPSFMTQRVGSSRSPSTSTFQNSDLQRDTSKRSEPSQSNIFAALEGGDDDEDE
InterPro domains: - IPR016024: Armadillo-type fold (homologous_superfamily) [702-948]
- IPR022745: Eukaryotic translation initiation factor 4G1, eIF4E-binding domain (domain) [470-538]
- IPR003890: MIF4G-like, type 3 (domain) [707-946]
- IPR036211: eIF4G, eIF4e-binding domain superfamily (homologous_superfamily) [462-556]
Interaction partners: - Eukaryotic translation initiation factor 4E
- ATP-dependent RNA helicase eIF4A
- Polyadenylate-binding protein, cytoplasmic and nuclear
- ATP-dependent RNA helicase
- Nuclear cap-binding protein complex subunit 1
- Tif3p
- Eukaryotic translation initiation factor 3 subunit B
- Nuclear cap-binding protein subunit 2
- Translation initiation factor eIF5
- Translation initiation factor eIF2 subunit beta
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0045182 (translation regulator activity), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:0090079 (translation regulator activity, nucleic acid binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0008135 (translation factor activity, RNA binding), GO:0003743 (translation initiation factor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0006970 (response to osmotic stress), GO:0009266 (response to temperature stimulus), GO:0104004 (cellular response to environmental stimulus), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0071214 (cellular response to abiotic stimulus), GO:0062197 (cellular response to chemical stress), GO:0071470 (cellular response to osmotic stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0016281 (eukaryotic translation initiation factor 4F complex), GO:0005737 (cytoplasm)