wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Leucine aminopeptidase 1 (EC 3.4.11.-) (Leucyl aminopeptidase 1) (LAP1) (Q8J2N2)
Organism: Aspergillus sojae
Function: Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.
Subcellular location: Secreted {ECO:0000250}.
Sequence: MRFLPCIATLAATASALAIGDHIRSDDQYVLELGPGETKVVTEAEKWALRAEGKRFFDITGRTSSLELASNKKQKLAVTYPDSVQHNETVQNLINSLDKKNFETVLQPFSEFHNRYYKSDNGKKSSEWLQGKIQEIISASGAKGVTVEPFKHFFPQSSLIAKIPGKSDKTIVLGAHQDSINLNSPSEGRAPSADDDGSGVVTILEAFRVLLTDEKVAAGEAPNTVEFHFYAGEEGGLLGSQDIFEQYLQKSRDVKAMLQQDMTGYTKGTTDAGKPESIGIITDNVDENLTKFLKIIVDAYCTIPTVDSKCGYGCSDHASATKYGYPAAFAFESAFGDDSPYIHSADDTIETVNFDHVLQHGRLTLGFAYELAFADSL
InterPro domains: - IPR045175: Peptidase M28 family (family) [81-357]
- IPR007484: Peptidase M28 (domain) [159-366]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008238 (exopeptidase activity), GO:0004177 (aminopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0006508 (proteolysis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Ionotropic receptor 100a (Q9V9T2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Sequence: MATTLQLIMLALVGGTLGQANNTDHKQVLTSIVKQLEGGLELHLRTSEDGGNDLVQFLMQEKSSIIISAKQEEVPSRAKIMRHHFFIFDGVHQMQEIRTSLFNTDGFYILALENNTIEDDVLLMEFAADVWLQHGHSRIYYVQLSKKSVLLFNPFLQRLVVVQDSKTYSRIYKDLEGYHLRIYIFDSVYSSVIGDGENKVLSVTGADAKLAKTVARQLNFTADFVWPDDEFFGGRLANGEYSGGVGRAHRGEVDIIFAGFFIKDYLTTHIQFSAAVYMDELCLYVKKAQRIPQSILPLFAVHMDVWLCFLLVGLLGALVWLILRAVNLILGIEGVPDGSRATRISYFGAARRIFVDTWVIWVRVNVGRFPPFHSERIFVASLCLVSVIFGALLESSLATVYIRPLYYRDVNTLRELDESGQPIYIKHPAFKDDLFYGHNSEVYRRLDAKMMLVAEGEERLIEMVSKRGGFAGVTRSASLQLSDIRYVMTKKVHKIPECPKNYHIAYVLPRPSPYLEEVNRIVLRLVAGGIVGLWTGEAKERAKWSIQRFPEYLAELDVGRWKVLTLSDVQLAFYALTIGCLLSAIVCMAEILLGRQRRLHSPK
InterPro domains: - IPR052192: Insect Ionotropic Receptors for Sensory Perception (family) [127-597]
Interaction partners: - Ionotropic receptor 11a
- IP13856p
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004984 (olfactory receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0003008 (system process), GO:0051606 (detection of stimulus), GO:0042221 (response to chemical), GO:0050906 (detection of stimulus involved in sensory perception), GO:0050877 (nervous system process), GO:0009593 (detection of chemical stimulus), GO:0007600 (sensory perception), GO:0050907 (detection of chemical stimulus involved in sensory perception), GO:0007606 (sensory perception of chemical stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0043235 (receptor complex), GO:0036477 (somatodendritic compartment), GO:0042995 (cell projection), GO:0097447 (dendritic tree), GO:0120025 (plasma membrane bounded cell projection), GO:0043005 (neuron projection), GO:0030425 (dendrite), GO:0071683 (sensory dendrite)
Protein: Branchpoint-bridging protein (A0A0R4IBT0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU367126}.
Sequence: MATGANATPLGKLHPSIGAKRGFDSGPGPGLMPPPGPSVPFPLQNFQPPQLSNPGFPQFPGAVSSALSNPIVVGQQSQAGGGDFGQKKRKRSRWSSETPDQKTVIPGMPTVIPPGLTRDQERAYIVQLQIEDLTRKLRTGDLGIPVNPEDRSPSPEPIYNSEGKRLNTREYRTRKKLEEERHSLITEMVGLNPEFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECCAKIMIRGKGSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSTEPRSITNTTLCTKCGGAGHISSDCKFTSSFAPRPGEPPQSAQDKARMDKEYLSLMAELGEAPVPSSGGGHNNAPPSGPRPSGPNNNQPPPNRPPWMNSGPTDNRNFHGMHQGPGGPHNFPPPMPNMGGPPMPPNPNGMPPPWMQPPPPPMGQGPAPPGHPMGLLPPPMGMMPPPPPPPNNQPPPPPSGPLPPWQQQAPPPPPTSSMATSAPMPWQQNTTTTSTPATGNLPPWQQPQQTAASASQPPPPMGNPSMVPPPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPMDPNFVTMMGIPGMPPYGMPPAPPPPPPQS
InterPro domains: - IPR036612: K Homology domain, type 1 superfamily (homologous_superfamily) [204-332]
- IPR045071: KH domain-containing BBP-like (family) [70-450]
- IPR004087: K Homology domain (domain) [206-299]
- IPR047086: Splicing factor 1, helix-hairpin domain superfamily (homologous_superfamily) [115-198]
- IPR055256: KHDC4/BBP-like, KH-domain type I (domain) [218-299]
- IPR001878: Zinc finger, CCHC-type (domain) [350-366]
- IPR032570: Splicing factor 1, helix-hairpin domain (domain) [90-202]
Interaction partners: - Splicing factor 3A subunit 2
- Splicing factor 3A subunit 1
- Splicing factor 3a, subunit 3.
- Cell division cycle 5-like protein
- Probable ATP-dependent RNA helicase DDX46
- Splicing factor U2AF subunit
- U2 snRNP auxiliary factor large subunit
- Splicing factor 3B subunit 1
- U1 small nuclear ribonucleoprotein C
- Pleiotropic regulator 1.
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0060041 (retina development in camera-type eye), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0043010 (camera-type eye development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Uncharacterized Nudix hydrolase P35G2.12 (EC 3.6.-.-) (Q9P791)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Sequence: MSQDQKPKVLEVSNLENQDAKWTSLKKIRWQDEKGKIRFWEMAERTTRSEANVDAVAILAIVPIDGSPHVLCQKQFRPPIGKFCIEIPAGLVDSKESCEDAAIRELREETGYVGTVMDSTTVMYNDPGLTNANLKIILADIDMSKPENQNPQQQLDDGEYIENFPIKLSSLQEELFSLEKKGFAIDVRLSTFALGLHAGLKYLSS
InterPro domains: - IPR020084: NUDIX hydrolase, conserved site (conserved_site) [90-111]
- IPR000086: NUDIX hydrolase domain (domain) [51-189]
- IPR015797: NUDIX hydrolase-like domain superfamily (homologous_superfamily) [16-177]
Interaction partners: - Phosphoglucomutase
- Ribose-phosphate pyrophosphokinase 1
- Ribose-phosphate pyrophosphokinase 2
- Ribose-phosphate pyrophosphokinase 5
- Probable phosphoribomutase
- SAGA complex subunit Sgf73
- SAGA complex subunit Sus1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Uncharacterized protein (Q57UT7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MSEEHANDSTLRVKVATINDKGEEVYASSLSHDGTYLAAVFGDGALVIFNPSTFSALDSSAAGKGYDNVPCTAVQWLESSEGGLYRLVSVSSAGGVFIWQWDGAALHRTNRVPEKGNEITCLAVSPECDMFITAGSDRTVRLYDADGTLKANLQMAHDESGVSRLAHTSRIFSVRFVSQGVAVSGGWGGPLQVWDLKANEARVEIRGAQVSSDGIELITGTNCVLVASRRQKEQLQVFDCVSGQELADDSARLSMALGELIPLSSRLCKTSGLVWTITSSPSKVLVTSYSTGQLIASYDSAYDLMNISIFEGLPNNAYISCAEGKLLFATVKQ
InterPro domains: - IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [6-322]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [14-296]
- IPR001680: WD40 repeat (repeat) [11-195]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0019222 (regulation of metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0010468 (regulation of gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0010608 (post-transcriptional regulation of gene expression), GO:0008380 (RNA splicing), GO:0006397 (mRNA processing), GO:0016071 (mRNA metabolic process), GO:0000398 (mRNA splicing, via spliceosome), GO:0000375 (RNA splicing, via transesterification reactions), GO:0000377 (RNA splicing, via transesterification reactions with bulged adenosine as nucleophile)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: SPI-2 type 3 secretion system translocon protein SctB (SPI-2 T3SS translocon protein SctB) (Secreted effector protein SseD) (Secretion system effector D) (Q9R803)
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. May act as a translocator that mediates translocation of SPI-2 TTSS effector proteins from intraphagosomal bacterial cells into the host cells.
Subcellular location: Secreted {ECO:0000269|PubMed:11159962, ECO:0000269|PubMed:11567004}. Cell surface {ECO:0000269|PubMed:11159962, ECO:0000269|PubMed:11567004}. Host membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}. Note=Secreted via the type III secretion system 2 (SPI-2 T3SS) (PubMed:11159962, PubMed:11567004). After secretion, localizes mainly on the surface of the bacterial cell (PubMed:11159962, PubMed:11567004). {ECO:0000269|PubMed:11159962, ECO:0000269|PubMed:11567004}.
Sequence: MEASNVALVLPAPSLLTPSSTPSPSGEGMGTESMLLLFDDIWMKLMELAKKLRDIMRSYNVEKQRLAWELQVNVLQTQMKTIDEAFRASMITAGGAMLSGVLTIGLGAVGGETGLIAGQAVGHTAGGVMGLGAGVAQRQSDQDKAIADLQQNGAQSYNKSLTEIMEKATEIMQQIIGVGSSLVTVLAEILRALTR
InterPro domains: - IPR008611: SPI-2 type 3 secretion system translocon protein SctB-like (family) [38-195]
Interaction partners: - SPI-2 type 3 secretion system translocon protein SctE
- Secretion system effector
- Secretion system chaparone
- Type III secretion system chaperone SseA
- Secreted effector protein SseB
- Secretion system apparatus protein SsaL
- Secretion system apparatus lipoprotein SsaJ
- Secretion system apparatus protein
- Secretion system chaparone
- Secretion system effector
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0055085 (transmembrane transport), GO:0140352 (export from cell), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0032940 (secretion by cell), GO:0045184 (establishment of protein localization), GO:0071806 (protein transmembrane transport), GO:0006810 (transport), GO:0030254 (protein secretion by the type III secretion system), GO:0035592 (establishment of protein localization to extracellular region), GO:0071702 (organic substance transport), GO:0046903 (secretion), GO:0071705 (nitrogen compound transport), GO:0008104 (protein localization), GO:0009306 (protein secretion), GO:0015031 (protein transport), GO:0071692 (protein localization to extracellular region)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: DNA-(apurinic or apyrimidinic site) endonuclease (EC 3.1.-.-) (E5KN95)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU362131}. Cytoplasm {ECO:0000256|RuleBase:RU362131}. Mitochondrion {ECO:0000256|RuleBase:RU362131}.
Sequence: MLRVVSWNINGIRRPLQGVANQEPSNCAAVAVGRILDELDADIVCLQETKVTRDALTEPLAIVEGYNSYFSFSRNRSGYSGVATFCKDNATPVAAEEGLSGLFATQNGDVGCYGNMDEFTQEELRALDSEGRALLTQHKIRTWEGKEKTLTLINVYCPHADPGRPERLVFKMRFYRLLQIRAEALLAAGSHVIILGDLNTAHRPIDHWDAVNLECFEEDPGRKWMDSLLSNLGCQSASHVGPFIDSYRCFQPKQEGAFTCWSAVTGARHLNYGSRLDYVLGDRTLVIDTFQASFLLPEVMGSDHCPVGAVLSVSSVPAKQCPPLCTRFLPEFAGTQLKILRFLVPLEQSPVLEQSTLQHNNQTRVQTCQNKAQVRSTRPQPSQVGSSRGQKNLKSYFQPSPSCPQASPDIELPSLPLMSALMTPKTPEEKAVAKVVKGQAKTSEAKDEKELRTSFWKSVLAGPLRTPLCGGHREPCVMRTVKKPGPNLGRRFYMCARPRGPPTDPSSRCNFFLWSRPS
InterPro domains: - IPR010666: Zinc finger, GRF-type (domain) [467-518]
- IPR004808: AP endonuclease 1 (family) [2-313]
- IPR005135: Endonuclease/exonuclease/phosphatase (domain) [5-304]
- IPR036691: Endonuclease/exonuclease/phosphatase superfamily (homologous_superfamily) [1-312]
- IPR020847: AP endonuclease 1, binding site (binding_site) [41-50]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0033554 (cellular response to stress), GO:0006259 (DNA metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0006974 (cellular response to DNA damage stimulus), GO:0006281 (DNA repair), GO:0006284 (base-excision repair)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0001650 (fibrillar center), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)
Protein: Ribose 5-phosphate isomerase (Q4CQE2)
Organism: Trypanosoma cruzi (strain CL Brener)
Function: Not known
Sequence: MTRRVAIGTDHPAFAIHENLILYVKEAGDEFVPVYCGPKTAESVDYPDFASRVAEMVARKEVEFGVLACGSGIGMSIAANKVPGVRAALCHDHYTAAMSRIHNDANIVCVGERTTGVEVIREIIITFLQTPFSGEERHVRRIEKIRAIEASHAGKKGVQ
InterPro domains: - IPR036569: Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily (homologous_superfamily) [1-159]
- IPR003500: Sugar-phosphate isomerase, RpiB/LacA/LacB family (family) [2-152]
- IPR004785: Ribose 5-phosphate isomerase B (family) [4-149]
Interaction partners: - Transketolase
- 6-phosphogluconate dehydrogenase, decarboxylating
- 6-phosphogluconate dehydrogenase, decarboxylating
- ribulose-phosphate 3-epimerase
- Ribulose-phosphate 3-epimerase
- Ribulose-phosphate 3-epimerase
- Phosphomannomutase-like protein, putative
- Ribokinase
- Ribose-phosphate pyrophosphokinase, putative
- ribose-phosphate diphosphokinase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016853 (isomerase activity), GO:0016860 (intramolecular oxidoreductase activity), GO:0016861 (intramolecular oxidoreductase activity, interconverting aldoses and ketoses)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006520 (amino acid metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006082 (organic acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:1901605 (alpha-amino acid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0009066 (aspartate family amino acid metabolic process), GO:0006531 (aspartate metabolic process), GO:0043648 (dicarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Asparagine--tRNA ligase, cytoplasmic 2 (EC 6.1.1.22) (Asparaginyl-tRNA synthetase 2) (AsnRS 2) (AtNS2) (Q9SW95)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Cytoplasm, cytosol {ECO:0000305|PubMed:16251277, ECO:0000305|PubMed:16297076}.
Sequence: MESHGKTHQKEHDNDLSPKPITLSKYSKRVELKTLLDRSDRGAGLAGKRVVIGGWVKSARAVKKNSPPPPLPVVAAPSPSSGGDQAHTTANIRCTEIIQSKMNIFKRFFDVLSGGGKTYPIFDKTELAGQKAVPPPEYVFYFLISDGSSISSLQVVVDSALSTVPATQLMALGTCIVAEGVLRLPLAASAKHVIELEAEKLLHVGTVDPEKYPLSKKQLPLHMLRDFSHFRPRTTTVGSVTRVHSALTLASHTFLQYHGFQYVQVPVITTTTGFGEMFRVTTLLGKTDDKEEKKPPVQEKDGFSIDTVKAVIKEKTRLIDHLKRSDSNRETVVAAVHDLKKTNDLASQIEMKQKSKTGTLVKPEKLDFSKDFFGRDTYLTASGRFHLESYASALGKVYTFGPRFIADKIDNARHLAEKWNVETEMAFAELDDAMDCADEYFKFLCKYVLENRDEDMKFISKRVDKTITTRLEATASSSLLRFSYTEVISLLQKATTTKFETKPEWGVALTTEHLSYLTDEIYKGPVIVHTYPKAIKQFYVRLNDDKKTVAAFDLVVPKVGVVITGSQNEERFEILDARIGESGFTREKFEWYLDLRRHGTVKHSGISLSMEQMLLYATGLPDIKDAIPFPRSWGKANN
InterPro domains: - IPR004522: Asparagine-tRNA ligase (family) [140-636]
- IPR004364: Aminoacyl-tRNA synthetase, class II (D/K/N) (domain) [370-631]
- IPR045864: Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (homologous_superfamily) [215-637]
Interaction partners: - Glutamyl-tRNA
- Glutamyl-tRNA
- Glutamyl-tRNA
- Proline--tRNA ligase, cytoplasmic
- Proline--tRNA ligase, chloroplastic/mitochondrial
- proline--tRNA ligase
- Putative glycine--tRNA ligase, cytoplasmic
- Protein SWOLLEN 1
- Histidine--tRNA ligase, cytoplasmic
- Histidine--tRNA ligase, chloroplastic/mitochondrial
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016874 (ligase activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0140098 (catalytic activity, acting on RNA), GO:0016875 (ligase activity, forming carbon-oxygen bonds), GO:0004812 (aminoacyl-tRNA ligase activity), GO:0140101 (catalytic activity, acting on a tRNA)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0003006 (developmental process involved in reproduction), GO:0009791 (post-embryonic development), GO:0048316 (seed development), GO:0009790 (embryo development), GO:0048608 (reproductive structure development), GO:0009793 (embryo development ending in seed dormancy), GO:0048731 (system development), GO:0061458 (reproductive system development), GO:0010154 (fruit development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0005773 (vacuole), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000325 (plant-type vacuole), GO:0043231 (intracellular membrane-bounded organelle)