Protein: Cryptochrome circadian regulator 3a (A0A8M1P943)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm. Nucleus
Sequence: MAPNSIHWFRKGLRLHDNPALQEAVRGADTVRCVYFLDPWFAGSSNLGVNRWRFLLQCLDDLDSNLRKLNSRLFVVRGQPANVFPRLFKEWKISRLTFEYDSEPFGKERDAAIKKLAMEAGVEVIVKTSHTLYNLDKIIELNGGQPPLTYKRFQTLISRMDPPEMPVETLSNSIMGCCVTPVSEDHGDKYGVPSLEELGFDIEGLPSAVWPGGETEALTRIERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYRKVKKTSTPPLSLYGQLLWREFFYTAATTNPRFDKMEGNPICVRIPWDKNPEALAKWAEAKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSVNAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDFIRRYLPILRGFPAKYIYDPWNAPDSVQAAAKCIIGVHYPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLLASVPSTHNGNGNGMAYSPGEQQSGTNTPAPAVSSGSVASGNRSGSILLNFDSEEHQGPSGIQQQHQQQQQQQQQQQLGYHHMPDSGHNSRFYKSNVSHDMAAGHLLHKGGSVTGKRERESERDLDGEDESLSTSHKLQRQIAEVTSVYASSGNQSSMRS
InterPro domains: - IPR002081: Cryptochrome/DNA photolyase class 1 (family) [4-551]
- IPR014729: Rossmann-like alpha/beta/alpha sandwich fold (homologous_superfamily) [6-212]
- IPR006050: DNA photolyase, N-terminal (domain) [3-156]
- IPR036134: Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily (homologous_superfamily) [196-489]
- IPR005101: Cryptochrome/DNA photolyase, FAD-binding domain (domain) [288-486]
- IPR036155: Cryptochrome/photolyase, N-terminal domain superfamily (homologous_superfamily) [4-214]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0009628 (response to abiotic stimulus), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0048523 (negative regulation of cellular process), GO:0009892 (negative regulation of metabolic process), GO:0009266 (response to temperature stimulus), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0009314 (response to radiation), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0009416 (response to light stimulus), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0051252 (regulation of RNA metabolic process), GO:0051253 (negative regulation of RNA metabolic process), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:0010468 (regulation of gene expression), GO:2001141 (regulation of RNA biosynthetic process), GO:1902679 (negative regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903507 (negative regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045892 (negative regulation of DNA-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005667 (transcription regulator complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)