Protein: PR domain zinc finger protein 14 isoform X1 (PR domain-containing 14) (F1QWQ9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Sequence: MSVSLSSHPAVRDRSLAVYPSLPGAHYADVLKSAHSIFHPLKSLGRMVTDAQTIMPFNFSGATPFFSHNSAIFHEQILNVSNIPYFQHIQPSQSVYNARHEDQSTGSLSDFSSPSSVKSSSALSSPVKDNFSCPQAAHPTPEHARTYSFTEEDLFTVLYGYSKKQGQNAGHAISGLSFPPSTADRQILPVDIEGFELPEGISILQTTCGSLSHYGAFADKSTIPKGTRFGPFQGKLVNTSEIKTYDDNTLMWEIFENGRLSHFVDGRGAPGNWMSLVKCARFPEEQNLIAVQCDGQIYYEACKEIRAGQELLVWYGDCYVQFLGIPLTLKEFIDDSEALPAEDSGEGFKCDRCGKVFAYKYYRDKHLKYTRCVDQGDRKFPCHLCNRSFEKRDRLRIHILHVHEKHRPHKCSVCGKSFSQSSSLNKHMRVHSGERPYKCVYCNKAFTASSILRTHIRQHSGERPFKCKHCGKAFASHAAHDSHVRRTHAKDKQLSCDVCGATFQEAQELKYHMKAHKKRPLLESSVVPPADENALFSTKESLHAQTQLADTFSFPGMTSISSEYRPWN
InterPro domains: - IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [378-517]
- IPR044408: PRDM14, PR/SET domain (domain) [195-327]
- IPR046341: SET domain superfamily (homologous_superfamily) [194-333]
- IPR013087: Zinc finger C2H2-type (domain) [348-518]
- IPR050331: Zinc finger (family) [197-522]
- IPR001214: SET domain (domain) [199-326]
Interaction partners: - CBFA2/RUNX1 partner transcriptional co-repressor 2.
- Nanos homolog 3
- Deleted in azoospermia-like
- POU domain, class 5, transcription factor 1
- Transcription factor AP-2 gamma
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0042592 (homeostatic process), GO:0002376 (immune system process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0007389 (pattern specification process), GO:0048871 (multicellular organismal-level homeostasis), GO:0009892 (negative regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0002262 (myeloid cell homeostasis), GO:0048523 (negative regulation of cellular process), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0001708 (cell fate specification), GO:0060255 (regulation of macromolecule metabolic process), GO:0060581 (cell fate commitment involved in pattern specification), GO:0031324 (negative regulation of cellular metabolic process), GO:0048872 (homeostasis of number of cells), GO:0045165 (cell fate commitment), GO:0034101 (erythrocyte homeostasis), GO:0003002 (regionalization), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0021517 (ventral spinal cord development), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0009790 (embryo development), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0080090 (regulation of primary metabolic process), GO:0030097 (hemopoiesis), GO:0021510 (spinal cord development), GO:0048665 (neuron fate specification), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0048663 (neuron fate commitment), GO:0021515 (cell differentiation in spinal cord), GO:0030099 (myeloid cell differentiation), GO:0010468 (regulation of gene expression), GO:0060573 (cell fate specification involved in pattern specification), GO:0022008 (neurogenesis), GO:0021511 (spinal cord patterning), GO:0048568 (embryonic organ development), GO:0007399 (nervous system development), GO:0030218 (erythrocyte differentiation), GO:0021514 (ventral spinal cord interneuron differentiation), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0007417 (central nervous system development), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0009953 (dorsal/ventral pattern formation), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0051252 (regulation of RNA metabolic process), GO:0002244 (hematopoietic progenitor cell differentiation), GO:0051253 (negative regulation of RNA metabolic process), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:0030182 (neuron differentiation), GO:0021953 (central nervous system neuron differentiation), GO:2001141 (regulation of RNA biosynthetic process), GO:0021513 (spinal cord dorsal/ventral patterning), GO:0006355 (regulation of DNA-templated transcription), GO:0035162 (embryonic hemopoiesis), GO:0048699 (generation of neurons), GO:1902679 (negative regulation of RNA biosynthetic process), GO:0060319 (primitive erythrocyte differentiation), GO:0006357 (regulation of transcription by RNA polymerase II), GO:0045892 (negative regulation of DNA-templated transcription), GO:0060215 (primitive hemopoiesis), GO:1903507 (negative regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0000122 (negative regulation of transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)