Protein: Branched-chain amino acid aminotransferase, putative (Q586R1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MTFLAKKIFVQRVANPPPLPSLQGVMFGTLFSPHMLVIDADGNGKWGKPRIVPFENLSLPPQTACLHYAIQCFEGMKAYRDSHGNIRLFRPDRNCRRLLDSTRRLCLPGFDPDELQKLIEEFVKVERDYVPSERGYSLYLRPTVIGTGSKLSAVAGSAAKLFVIASPVGPYYPSGMKPVRLHVEEERRRAWPGGVGNVKLGANYAAPMLVQQEASELGFQQVLWLGAGEEVQEVGAMNFMCLWRPSANSNEVELVTAPLDGTILPGVTRDSILSLVRQWGEARVSERSFTIHELTAALREKRVLECFGCGTAAIVSPVEALSYKGELLNVPCPAPGASLTHRVLKAITDIQYGDVEHEWSRIVGTTS
InterPro domains: - IPR001544: Aminotransferase class IV (family) [71-319]
- IPR005786: Branched-chain amino acid aminotransferase II (family) [2-365]
- IPR043131: Branched-chain-amino-acid aminotransferase-like, N-terminal (homologous_superfamily) [27-359]
- IPR043132: Branched-chain-amino-acid aminotransferase-like, C-terminal (homologous_superfamily) [173-348]
- IPR036038: Aminotransferase-like, PLP-dependent enzymes (homologous_superfamily) [8-362]
- IPR033939: Branched-chain aminotransferase (family) [58-353]
Interaction partners: - 3-methyl-2-oxobutanoate dehydrogenase
- 2-oxoisovalerate dehydrogenase subunit alpha
- Homoserine kinase, putative
- Branched-chain amino acid aminotransferase, putative
- Glutamate--cysteine ligase
- Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
- hydroxymethylglutaryl-CoA lyase
- Bifunctional dihydrofolate reductase-thymidylate synthase
- Phosphonopyruvate decarboxylase-like protein, putative
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016769 (transferase activity, transferring nitrogenous groups), GO:0008483 (transaminase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0006082 (organic acid metabolic process), GO:0019538 (protein metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006520 (amino acid metabolic process), GO:0043094 (cellular metabolic compound salvage), GO:0043170 (macromolecule metabolic process), GO:0006790 (sulfur compound metabolic process), GO:0036211 (protein modification process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0043412 (macromolecule modification), GO:0000096 (sulfur amino acid metabolic process), GO:0044272 (sulfur compound biosynthetic process), GO:0043436 (oxoacid metabolic process), GO:0008652 (amino acid biosynthetic process), GO:0016053 (organic acid biosynthetic process), GO:0009081 (branched-chain amino acid metabolic process), GO:0043102 (amino acid salvage), GO:1901605 (alpha-amino acid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0071267 (L-methionine salvage), GO:1901607 (alpha-amino acid biosynthetic process), GO:0009066 (aspartate family amino acid metabolic process), GO:0000097 (sulfur amino acid biosynthetic process), GO:0046394 (carboxylic acid biosynthetic process), GO:0006555 (methionine metabolic process), GO:0009086 (methionine biosynthetic process), GO:0009067 (aspartate family amino acid biosynthetic process), GO:0071265 (L-methionine biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0099568 (cytoplasmic region), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005929 (cilium), GO:0032838 (plasma membrane bounded cell projection cytoplasm), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0097014 (ciliary plasm), GO:0005634 (nucleus)