Protein: Glucocorticoid receptor (Nuclear receptor subfamily 3 group C member 1) (Q6RKQ3)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Function: Not known
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm, cytoskeleton, spindle {ECO:0000256|ARBA:ARBA00004186}. Mitochondrion {ECO:0000256|ARBA:ARBA00004173}. Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|RuleBase:RU004334}.
Sequence: MDSLIGDSDPNLFPMSMRTETAFSRDQNPMDMDQEGYIGKDQKLFSDNTLDLLQDFELTGSPSDFYVGDDAFLSSLADDTLLGDESQDRGVSNSTSKPAATMTNSGSFSGSNTTTLNGSSLLACQDESNSSTSMTTTATFPMVKMEKESGFIQLCTPGVIKQENTSAMRSSSCQMSGSTGGSTSSSPSELSSSSPSPISICGVSTSGGQSYHFGGNSSINTTLASTTSGASQQKDQKPSVFSLYPPLVTVGEAWNNISYGDGASGMQGLSSPTSAFSSSYASSTSKLGGGAASCTTQGKAGTTHKVCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGTGARGQHNYLCAGRNDCIIDKIRRKNCPACRFRKCLLAGMNLEARKTKKLNRLKGVQQPTTAELTPRPLPEARSLVPKSMPQLTPTMLSLLKAIEPDTIYSGYDGTLPDTSTRIMTTLNRLGGRQVVSAVKWAKALPGFRNLHLDDQMTLLQCSWLFLMSFGLGWRSYQQCDGNMLCFAPDLVINQDRMKLPYMADQCEQMLKISSEFVRLQVSHDEYLCMKVLLLLSTVPKDGLKSQAVFDEIRMSYIKELGKAIVKREENSSQNWQRFYQLTKLLDSMHEMVGGLLDFCFYTFVNKSLSVEFPEMLAEIISNQLPKFKAGSVKPLLFHQK
InterPro domains: - IPR001409: Glucocorticoid receptor (family) [18-283]
- IPR035500: Nuclear hormone receptor-like domain superfamily (homologous_superfamily) [395-669]
- IPR000536: Nuclear hormone receptor, ligand-binding domain (domain) [416-650]
- IPR050200: Nuclear hormone receptor family NR3 subfamily (family) [164-649]
- IPR001628: Zinc finger, nuclear hormone receptor-type (domain) [304-384]
- IPR001723: Nuclear hormone receptor (family) [373-563]
- IPR013088: Zinc finger, NHR/GATA-type (homologous_superfamily) [298-402]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0060089 (molecular transducer activity), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0008289 (lipid binding), GO:0038023 (signaling receptor activity), GO:0097159 (organic cyclic compound binding), GO:0042562 (hormone binding), GO:0003676 (nucleic acid binding), GO:0003707 (nuclear steroid receptor activity), GO:0005496 (steroid binding), GO:0098531 (ligand-activated transcription factor activity), GO:1990239 (steroid hormone binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003677 (DNA binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding), GO:0001046 (core promoter sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009893 (positive regulation of metabolic process), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0009719 (response to endogenous stimulus), GO:0060255 (regulation of macromolecule metabolic process), GO:1901700 (response to oxygen-containing compound), GO:0010035 (response to inorganic substance), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0010038 (response to metal ion), GO:0048545 (response to steroid hormone), GO:0097305 (response to alcohol), GO:0010628 (positive regulation of gene expression), GO:0014070 (response to organic cyclic compound), GO:1901654 (response to ketone), GO:0033993 (response to lipid), GO:0010468 (regulation of gene expression), GO:0046688 (response to copper ion), GO:0031960 (response to corticosteroid), GO:0051414 (response to cortisol), GO:0051384 (response to glucocorticoid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0045178 (basal part of cell), GO:0097574 (lateral part of cell), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)