Protein: Myosin-10 (Myosin XI D) (AtXID) (F4IVR7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Myosin heavy chain that is required for the cell cycle-regulated transport of various organelles and proteins for their segregation. Functions by binding with its tail domain to receptor proteins on organelles and exerting force with its N-terminal motor domain against actin filaments, thereby transporting its cargo along polarized actin cables (By similarity).
Sequence: MVWKHQLIGFSGIFSNVSPASVKVTVGSQVWVEDPDEAWLDGEVVEANGQEIKVNCQTKTVVAKVNAVHPKDPEFPELGVDDMTKLAYLHEPGVLLNLKARYNANEIYTYTGNILIAVNPFKRLPHLYGNEIMEQYKGTDFGELSPHPFAVADSAYRKMINEGVSQAILVSGESGAGKTESTKMLMQYLAYMGGKAESEGRSVEQQVLESNPVLEAFGNAKTVRNNNSSRFGKFVEIQFNHMGRISGAAIRTYLLERSRVCQVSDPERNYHCFYMLCAAPEQETERYQLGKPSTFHYLNQSNCHALDAIDDSKEYLATRKAMDVVGISPEEQDAIFRVVAAILHLGNIEFAKSEESDGAEPKDDKSRFHLKVAAKLFMCDEKALENSLCNRVMVTRGESITKPLDPGSAALSRDALAKIVYSKLFDWLVTKINNSIGQDSSSKYIIGVLDIYGFESFKTNSFEQFCINLTNEKLQQHFNQHVFKMEQEEYTKEEIDWSYIEFIDNQDVLDLIEKKPGGIIALLDEACMFPRSTHDTLAEKLYQTFGSHKRFTKPKLARTDFTICHYAGDVTYQTELFLDKNKDYVVGEHQSLMNSSDCSFVSSLFPKSREESSKSSKFSSIGSQFKQQLQSLLETLNTTEPHYIRCVKPNNVLKPEIFENVNVLHQLRCGGVMEAIRISCAGYPTRKPFNEFLTRFRILAPEATERSFDEVDACKKLLARVDLKGFQIGKTKVFLRAGQMAELDAHRAEVLGHSARIIQRKVITYLSRKKYLLLQSASTEIQAFCRGHIARVQFKATRREAASVRIQKQARTYICQTAFKKLCASAISIQSGLRAMAARVEFQYRTKRKAAIIIQSQIRRCLCRRRYLRTKKAAITTQCGWRVKVAHRELRKLKMAAKETGALQDAKTKLEKEVEELTSCLELEKQMRMELEQVKTQEVEDLRSALNDMKLQLGETQVTKSEEILKLQSALQDMQLEFEELAKELEMTNDLAAENEQLKDLVSSLQRKIDESDSKYEETSKLSEERVKQEVPVIDQGVIIKLEAENQKLKALVSTLEKKIDSLDRKHDVTSSNISDQLKESASSDYEMLSNLAAENERLKALVSSLENENYENDGNDSPNEQKEGPQMLKEEILAEDFSIDDEMTNKLAAENKDLYDLVDLLERKIDETEKKYEEASKLCEERLKQVVDTEKKYEEASRLCEERLKQVVDTETKLIELKTSMQRLEEKVSDMEAEDKILRQQALRNSASRKMSPQKSLDLFVFMYLFQPVENGHHESFAPIPSRRFGAMSFRRSQIEQQPHEFVDVLLKCVSKNVGFSHGKPVAAFTIYKCLIHWKLFEAEKTSVFDRIVPIFGSAIENPEDDSNLAYWLTNTSTLLFLLQRSLKSHSTTGASPKKPPQPTSFFGRMTQGFRSPSSASLSGDVVQQVDARYPALLFKQQLTAYIETIYGIFQENVKRKLAPVLSSCIQGLKDSSHEFSAETLSAESSEQNSPEKPSEENPPEKLSEDNSSGKLSEDYLAAKPSEDNSPAKPSEENSQAKLSEVNPQAKPSAENSLAKPSEENSPTETWQDVIGLLNQLLGTLKKNYVPLFLAQKIFCQTFQDINVQLFNSLLQRECCTFIMGKKVNVWLNELESWCSQATEDFVGSSWDELKNTRQALVLLVTEQKSTITYDDLTTNLCPALSTQQLYRICTLCKIDDHEDQNVSPDVISNLKLLVTDEDEDSRSFLLDNNSSIPFAADEISNSMQEKDFTNVKPAVELADNPNFHFLKE
InterPro domains: - IPR000048: IQ motif, EF-hand binding site (binding_site) [750-891]
- IPR036018: Plant myosin, class XI, motor domain (domain) [92-736]
- IPR002710: Dilute domain (domain) [1347-1718]
- IPR004009: Myosin, SH3 domain (domain) [25-73]
- IPR001609: Myosin head, motor domain-like (domain) [72-749]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [53-899]
- IPR036961: Kinesin motor domain superfamily (homologous_superfamily) [81-678]
- IPR037975: Class XI myosin, cargo binding domain (domain) [1298-1739]
Interaction partners: - Protein trichome birefringence
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0030029 (actin filament-based process), GO:0030048 (actin filament-based movement)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0042579 (microbody), GO:0043229 (intracellular organelle), GO:0019867 (outer membrane), GO:0043227 (membrane-bounded organelle), GO:0005740 (mitochondrial envelope), GO:0031968 (organelle outer membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0005777 (peroxisome), GO:0098588 (bounding membrane of organelle), GO:0031966 (mitochondrial membrane), GO:0005741 (mitochondrial outer membrane)