Protein: AP-1 complex subunit gamma (B3KXW5)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000256|ARBA:ARBA00004156}. Endomembrane system {ECO:0000256|ARBA:ARBA00029433}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00029433}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00029433}. Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}.
Sequence: MEKNINLRNCQTLNTYVMLTHLRMPAPIRLRELIRTIRTARTQAEEREMIQKECAAIRSSFREEDNTYRCRNVAKLLYMHMLGYPAHFGQLECLKLIASQKFTDKRIGYLGAMLLLDERQDVHLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFRKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLLRILGRNDDDSSEAMNDILAQVATNTETSKNVGNAILYETVLTIMDIKSESGLRVLAINILGRFLLNNDKNIRYVALTSLLKTVQTDHNAVQRHRSTIVDCLKDLDVSIKRRAMELSFALVNGNNIRGMMKELLYFLDSCEPEFKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGSSIDVELQQRAVEYNALFKKYDHMRSALLERMPVMEKVTTNGPTEIVQTNGETEPAPLETKPPPSGPQPTSQANDLLDLLGGNDITPVIPTAPTSKPSSAGGELLDLLGDINLTGAPAAAPAPASVPQISQPPFLLDGLSSQPLFNDIAAGIPSITAYSKNGLKIEFTFERSNTNPSVTVITIQASNSTELDMTDFVFQAAVPKTFQLQLLSPSSSIVPAFNTGTITQVIKVLNPQKQQLRMRIKLTYNHKGSAMQDLAEVNNFPPQSWQ
InterPro domains: - IPR016024: Armadillo-type fold (homologous_superfamily) [45-622]
- IPR050840: Adaptor Complexes Large Subunit (family) [31-832]
- IPR013041: Clathrin adaptor, appendage, Ig-like subdomain superfamily (homologous_superfamily) [718-844]
- IPR017107: Adaptor protein complex AP-1, gamma subunit (family) [26-843]
- IPR008152: Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain (domain) [722-840]
- IPR011989: Armadillo-like helical (homologous_superfamily) [15-611]
- IPR002553: Clathrin/coatomer adaptor, adaptin-like, N-terminal (domain) [46-596]
- IPR008153: Gamma-adaptin ear (GAE) domain (domain) [725-840]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0030742 (GTP-dependent protein binding), GO:0019899 (enzyme binding), GO:0008092 (cytoskeletal protein binding), GO:0019894 (kinesin binding), GO:0051020 (GTPase binding), GO:0031267 (small GTPase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0051640 (organelle localization), GO:0006903 (vesicle targeting), GO:0051649 (establishment of localization in cell), GO:0051648 (vesicle localization), GO:0046907 (intracellular transport), GO:0051656 (establishment of organelle localization), GO:0048199 (vesicle targeting, to, from or within Golgi), GO:0006810 (transport), GO:0016482 (cytosolic transport), GO:0016192 (vesicle-mediated transport), GO:0007034 (vacuolar transport), GO:0051650 (establishment of vesicle localization), GO:0006895 (Golgi to endosome transport), GO:0048193 (Golgi vesicle transport), GO:0006896 (Golgi to vacuole transport), GO:0006892 (post-Golgi vesicle-mediated transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005829 (cytosol), GO:0031984 (organelle subcompartment), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0098791 (Golgi apparatus subcompartment), GO:0005794 (Golgi apparatus), GO:0005773 (vacuole), GO:0043227 (membrane-bounded organelle), GO:0055037 (recycling endosome), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0032588 (trans-Golgi network membrane), GO:0012506 (vesicle membrane), GO:0005802 (trans-Golgi network), GO:0030135 (coated vesicle), GO:0005774 (vacuolar membrane), GO:0031982 (vesicle), GO:0030659 (cytoplasmic vesicle membrane), GO:0000139 (Golgi membrane), GO:0005764 (lysosome), GO:0097708 (intracellular vesicle), GO:0030136 (clathrin-coated vesicle), GO:0098852 (lytic vacuole membrane), GO:0005765 (lysosomal membrane)