Protein: ADP ribosylation factor interacting protein 2 (A0A087X1E4)
Organism: Homo sapiens (Human)
Subcellular location: Golgi apparatus, trans-Golgi network membrane
Sequence: MTDGILGKAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGDGLIPTGKSISCARREVWVGPQRCLVYLREAGVRELDPLGSGRHPSHSTTPSGPGDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGRGSRTVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEELSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLLFHNAVSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ
InterPro domains: - IPR027267: AH/BAR domain superfamily (homologous_superfamily) [151-351]
- IPR030798: Arfaptin family (family) [6-374]
- IPR010504: Arfaptin homology (AH) domain (domain) [122-354]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0008289 (lipid binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0097367 (carbohydrate derivative binding), GO:0005515 (protein binding), GO:0030742 (GTP-dependent protein binding), GO:1901265 (nucleoside phosphate binding), GO:0005543 (phospholipid binding), GO:0042802 (identical protein binding), GO:0043168 (anion binding), GO:0000166 (nucleotide binding), GO:0050839 (cell adhesion molecule binding), GO:0019899 (enzyme binding), GO:0032553 (ribonucleotide binding), GO:0035639 (purine ribonucleoside triphosphate binding), GO:0045296 (cadherin binding), GO:0035091 (phosphatidylinositol binding), GO:0051020 (GTPase binding), GO:0032555 (purine ribonucleotide binding), GO:0017076 (purine nucleotide binding), GO:0005525 (GTP binding), GO:0019001 (guanyl nucleotide binding), GO:0031267 (small GTPase binding), GO:0032561 (guanyl ribonucleotide binding), GO:1901981 (phosphatidylinositol phosphate binding), GO:0070273 (phosphatidylinositol-4-phosphate binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0051641 (cellular localization), GO:0044237 (cellular metabolic process), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0030029 (actin filament-based process), GO:0061919 (process utilizing autophagic mechanism), GO:0033036 (macromolecule localization), GO:0009056 (catabolic process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0044085 (cellular component biogenesis), GO:0035556 (intracellular signal transduction), GO:0044248 (cellular catabolic process), GO:0070727 (cellular macromolecule localization), GO:0016043 (cellular component organization), GO:0030036 (actin cytoskeleton organization), GO:0006914 (autophagy), GO:0016236 (macroautophagy), GO:0030030 (cell projection organization), GO:0000422 (autophagy of mitochondrion), GO:0008104 (protein localization), GO:0007264 (small GTPase mediated signal transduction), GO:0006996 (organelle organization), GO:0022411 (cellular component disassembly), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0007010 (cytoskeleton organization), GO:0007005 (mitochondrion organization), GO:0007033 (vacuole organization), GO:0000423 (mitophagy), GO:0034497 (protein localization to phagophore assembly site), GO:1905037 (autophagosome organization), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0061912 (selective autophagy), GO:1903008 (organelle disassembly), GO:0000045 (autophagosome assembly), GO:0120031 (plasma membrane bounded cell projection assembly), GO:0097581 (lamellipodium organization), GO:0031529 (ruffle organization), GO:0061726 (mitochondrion disassembly), GO:0030032 (lamellipodium assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0031252 (cell leading edge), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0005829 (cytosol), GO:0031984 (organelle subcompartment), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0031090 (organelle membrane), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0005938 (cell cortex), GO:0001726 (ruffle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0098791 (Golgi apparatus subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0032588 (trans-Golgi network membrane), GO:0005802 (trans-Golgi network)