Protein: Msx2-interacting protein (F1QMN6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
Sequence: MVRETRHLWVGNLPENVREEKIIEHFKRYGRVESVKVLPKRGSEGGVAAFVDFVDIKSAQKAHNSINKMGDRDLRTDYNEPGTIPSAARGLDDSLSIATRGRDVSGFTRGAGGPVYGPSVSLHSREGRFERRLDGTSDSRERSYDHSAYGHHERSSSNSTSFDRQRHYESDYYRDSRDRALSGTSGSASSASGSIGGSSSAGSIGVAGNVAGSSGAGGSTAAGVGSGGSTPGGIVYYGSRSRSPSRFETTETRYEPRAREAFTLASVVHRDLFREERGRRGERTYHHSRSRSPHSSQSHNPSPQRLQSQAARPARSRSGSGSRSRSSSSDSVSSTSSSGSGSSDSSSTSSDRSPARSVQSTAVPAPSTQPLPSLDKDEPRKSFGIKVQNLPVRSTDTSLKDGLFHEFKKHGKVTSVQIHGASEERYGLVFFRQQEDQEKALSASKGKLFFGMQIDVTAWHGPETESENEFRPLDERIDEFHPKATRTLFIGNLEKTTTYNDLLNIFQRFGEIVDIDIKKVNGSPQYAFLQYCDIASVCKAIKKMDGEYLGNNRLKLGFGKSMPTTCVWLDGLSSSITEQYLTRHFCRYGHVVKVVFDRLKGMALILYNNIEYAQAAVKETKGWKIGGNKIKVDFANQESQMAFYRSMQGSGQDIRDFYEIISERRDERRTPYHEFTAERAYYENVRTPTSYTEDPRRKYPARSREFFSEWDPYQGDYYDPRYYDDSREYRDFRDPYEQDIRKYSYLQRERERERERFETDRERDHGRRTIEHQQSPTHSRRPASPTASPSLSERPPSDSEHHVYSRSSERSGSCSSLSPPRFEKPDKIRLERHNRNDKLEKEKSLFETERGNGGEKERRAGRKEKGEKDRTERQKLKKLKLASPTVPSPEAELELDRDASPEANITLRGKVSKSLIKDKDYSGKGKLDLLPCVVQLTRVKEKEGKLIDSILCEKQKTKVGSDPVLSPTTPSSGDHKSMPFRKDTQARDFFKHGKHLKEKGLASQVEVVDKEEKVKNKKYFKSDLAFESSSSVDADRKAARKRRFEETSAKADNLRRVSQEEDEGKLRRIIDEPLLKDTDYDKKLLRKEAHKRERKIKPERMVTVSTTIEELDNVMPVGPSLDLQARLGEPAEDAIDPLDSLDQKIGAFGANRQPSFSLAVSDDGSVDMDFSREQEQQHLTSYHTLSSRQERVSESKESLLSDIDHSQSCRKQMEQNRRLQQQMLECDKSDKTESTPSTDAEEFEHRSIVHEVVKPLQDVTGSSPTSKQKKLGGFEFDFGKREQNYEMFRLRNDEPERGLASHPGTPLAEEERNASQLLDKDPDLPVTMDKNSSHLDVSKYNTSNAVHQGLSPHAEILKVKPSVTKEEFSWESNIRQGTLREMSFPTSIVKRESIRKRPERELEPGEVQSDSDEDESRHYSLKPISFKREHEERLSDVKYSESLEKNKFYEFALDKTITPDTKALLERAKSLSSSREENWFFLNHDSKFKSLQNNIDKEKSEPTPRPIPSWYLKKKKSRSDSDGKLDEKKQDAKPDEQERQDLLASRFLHSSIFEQDSRRLQHLERKNTDPDVRIGRDSVTSNSQGEQPGTGGSDLTQEPRVLFHSRFLELQQRDKNQQLPISEKLSLTDQMEKTLDEEFRPSPNLSDISQESLASHSLTPTISPVSQSKISEMSVHHEKPVLHTTLPNIHNPAVVNVRSENAPIDYPSLISLKDENNTIPLSTPSPEPMIKEDVIVEEPEEKLRDSRKTVHAAVEHEIEIKPPTPGASLGNVEPECDALQASSPLYPNPSKDQETTELSETTTEPANSSLVVSPLEVPDTEIEQVEQVLPPRKQPKSKKVKNVSSAQTPITQVVNEKPATRKSERIDKEKLKRSPRGDSTKLTADSRNSAKSPVQVLDSEQGLELNTNQGRTRQRRNVRSVYATPPEEESPQQQGKEVTEPPRSTLKRSRGRPPKTRRRVDDMSPVKGDQIKNSEAEDTENKESTSSGEITKSTEAWRSPRSQKGQSSPIRSGQSKKTLKLDKVSGTSACVQLDREAVDVPPALDRKAESKETLMQVGHLSKDTKQNSISTREKELVAEEISTDDRVEITPVEKILDKEVKTSRSTRNTKTMSDNKAVNVVKLTMDAVKEAVHSGDDITVCFEGSLKANVPQSVIEQSDIQDYHKKENVNSLDEKDETLSEMEPPTDPVAALLARQMELERAVENISRFTDDQHPVPYKEPRTEPPTLTAPVVVQPAEDTEVGKPANPASETELAEAINSITAEDISGDTDGFSASTTYTTLLPQPETLDLPVPNEVVETESDLTVKTIAQSEQDNVMVPVSKSSKCKTDTSLKESPLTEVAKRGGRARPKTAKKSRGRKVSLNRKLDIAEDVVLEPESTTVKLPESIPEEIQTVNPKAATSAAAAAVVTVAAACKHEAASTVILNTPKEAEQPAVDQPEPQESAFHSGNNSPSYLRTQQSSPERGASALTSPTTRLNSPASSNIPPEWNTRTEEKVMLPKPQGNVALSIPGAGGPPANPPMPPDTKASDINASSSTLRKILMEPKYVSASNSNSVTSMQFTTTLADPRMSDNENSVEAVLPLKTSLPEDRPSPIAQLVPRTTPPQPPPLQQCETPQILKEKLAITSTATSVISRIPMPFDFEDTPRISLSNRNSGMSLPKQKYRTGLNENNRYHGHNTSEDGGSVGRPVVEGTHCNTGSSTGLRVNTSEGVVVLSYSGQKTEGPQRIIAKISQIPPASAVDIEFQQSITKSQIKQEPSSHPSTPKGSQTPTGYSHTGVVLAGQSINAQPVISSIRQESPGSEKSETSYQQGSSLKSFHQSPSHPQLLRYGQSITPQHHMKKNGETESFSMKADIKPDIKATQTFNVKPVLSPRHPSFSGNHILSPSAPHERAVPQPKQDSHSPRASNHSMSPFPKVCPPNSPVVLGPAGPMSQYVSNIHHAEQSVIMPPHSVTQSVPMSHLSQGDVRASTPTLSGIGYGLRSENLLSPRSAPPQRSTTPQPAVIRDVILKSHAGSSVGGHVVETSNDDAQNLPQGLRRSSAPQLQQESMVIQSEFKNLHHRALRLDQYARLMQQHLTDHPGVVESRQTRTAEVVQSSSHISSASSKASSIVKNAPQIVRDGQKTVELKMSPSPHSDNRITGHPPGSVMVSPQGVQLNYPGNGNTMNEYYKEMRGFHPQYPGHSVIGINLANRGIPVSQVSQIDHSQRHKVPSLSSSESVGSFSESKLEGSHIRHSGTMDLSHISRVQSEAGSPSYISPVTITPKLELAITLQKGPQGPVSNKMPLPSLASSQMRSDFKLDHTGLRSVDMVQLLTKYPIIWQGHLALKNDTAAVQLHFVSGNNVLAHRSLPPPEGGAFLRIAQRMRLEASQLEGVARRMTAENEYCLLLALPCGLDQEDVHNQTHALKTGFITYLQAKQAAGIINVPNPGSNQPAYVVQIFPPCEFSESHLSHLAPDLLNSISSISPHLMIVIASV
InterPro domains: - IPR012921: Spen paralogue and orthologue SPOC, C-terminal (domain) [3314-3474]
- IPR016194: SPOC-like, C-terminal domain superfamily (homologous_superfamily) [3307-3476]
- IPR035979: RNA-binding domain superfamily (homologous_superfamily) [5-638]
- IPR049095: Msx2-interacting protein, MID domain (domain) [2097-2398]
- IPR034175: SHARP, RNA recognition motif 4 (domain) [558-634]
- IPR049093: Msx2-interacting protein, nuclear receptor-interacting domain (domain) [2422-2650]
- IPR010912: Spen paralogue/orthologue C-terminal, metazoa (domain) [3310-3476]
- IPR000504: RNA recognition motif domain (domain) [6-637]
- IPR034173: SHARP, RNA recognition motif 2 (domain) [384-457]
- IPR034174: SHARP, RNA recognition motif 3 (domain) [484-557]
- IPR034172: SHARP, RNA recognition motif 1 (domain) [7-81]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [2-655]
Interaction partners: - Leucine zipper protein 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0042221 (response to chemical), GO:0007389 (pattern specification process), GO:0051716 (cellular response to stimulus), GO:0003008 (system process), GO:0009887 (animal organ morphogenesis), GO:0003002 (regionalization), GO:0030154 (cell differentiation), GO:0070887 (cellular response to chemical stimulus), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0001708 (cell fate specification), GO:0009799 (specification of symmetry), GO:1901700 (response to oxygen-containing compound), GO:0003013 (circulatory system process), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0009855 (determination of bilateral symmetry), GO:0003018 (vascular process in circulatory system), GO:0032870 (cellular response to hormone stimulus), GO:0008015 (blood circulation), GO:0060972 (left/right pattern formation), GO:0071310 (cellular response to organic substance), GO:0072359 (circulatory system development), GO:0003015 (heart process), GO:0003143 (embryonic heart tube morphogenesis), GO:1901701 (cellular response to oxygen-containing compound), GO:0007507 (heart development), GO:0061371 (determination of heart left/right asymmetry), GO:0007368 (determination of left/right symmetry), GO:0060047 (heart contraction), GO:0071407 (cellular response to organic cyclic compound), GO:0001947 (heart looping)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)