Protein: Cholinergic receptor, nicotinic, beta 4 (neuronal) (Neuronal acetylcholine receptor subunit beta-4) (A0A0R4ISQ3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034104}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00034104}.
Sequence: MGLKRCRIPAGSSMTRALCVLLCALSLARSGVCADSEERLMNWLLGKHRYNKLIRPALNRTERVTVLLQVSLAQLISVNEREQIMTTNVWLTQNWNDYRLSWDPAEYEGIDKLRIPSRHIWLPDIVLYNNADGTYEVTVFTNAIVLFNGSIAWLPPAIYKSACKIEVKHFPFDQQNCTLKFRSWTYDHTEIDLLLKSDAASMDDFTPSGEWDILALPGRRTVSPLDATYVDLTYDFIIKRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLIGKYLMFTMVLVTFSIITSVCVLNVHHRSPSTHSMPAWVKIVFLVRLPALLFMQRPRGHSARQRLRQNRRLLGLADTPGRSVMCSSASALLAASSASALSSPGLLYNKGHFGSRRAEGLNNGHGSAQDLKGNRLYCEWGSEIQEAVDGVRYVADHMMGNDDDQSVIEDWKYVAMVVDRLFLWIFVIVCVVGTLGLFLQPLFQNQTLAIQQPNTEPARRDGM
InterPro domains: - IPR038050: Neuronal acetylcholine receptor (homologous_superfamily) [248-515]
- IPR006201: Neurotransmitter-gated ion-channel (family) [19-500]
- IPR036734: Neurotransmitter-gated ion-channel ligand-binding domain superfamily (homologous_superfamily) [30-247]
- IPR018000: Neurotransmitter-gated ion-channel, conserved site (conserved_site) [163-177]
- IPR002394: Nicotinic acetylcholine receptor (family) [73-161]
- IPR036719: Neurotransmitter-gated ion-channel transmembrane domain superfamily (homologous_superfamily) [242-506]
- IPR006029: Neurotransmitter-gated ion-channel transmembrane domain (domain) [249-500]
- IPR006202: Neurotransmitter-gated ion-channel ligand-binding domain (domain) [37-242]
Interaction partners: - Cholinergic receptor, nicotinic, alpha 3.
- Acetylcholine receptor subunit alpha
- Cholinergic receptor nicotinic beta 3 subunit b
- Neuronal acetylcholine receptor subunit alpha-5
- Cholinergic receptor, nicotinic, alpha 6.
- Cholinergic receptor, nicotinic, alpha 4b
- Cholinergic receptor, nicotinic, alpha 2a
- Cholinergic receptor, nicotinic, alpha 7
- Cholinergic receptor, nicotinic, beta 1
- Acetylcholine receptor subunit gamma precursor
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0030594 (neurotransmitter receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0015464 (acetylcholine receptor activity), GO:0098960 (postsynaptic neurotransmitter receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0007267 (cell-cell signaling), GO:0007154 (cell communication), GO:0099536 (synaptic signaling), GO:0099537 (trans-synaptic signaling), GO:0098916 (anterograde trans-synaptic signaling), GO:0007268 (chemical synaptic transmission), GO:0007271 (synaptic transmission, cholinergic)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0043235 (receptor complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:1990351 (transporter complex), GO:0098802 (plasma membrane signaling receptor complex), GO:0098797 (plasma membrane protein complex), GO:1902495 (transmembrane transporter complex), GO:0005886 (plasma membrane), GO:0034702 (ion channel complex), GO:0005892 (acetylcholine-gated channel complex)