Protein: Activating transcription factor 1 (F7FD47)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MEDSHKSNTSETASQPGSTVPGIISQIVHQVSSLSESEESQDSSDSIGSSQKAHGILARRPSYRKILKDLSSEDTRGRKGDGENPSISAVTSMSVPTPIYQTSSGQYIAIAPNGALQLASPGPDGVQALQTLTMTNSSSAQQGAILQYAQTSDGQQILVPSNQVVVQTASGDMQTYQIRTTPSATSLPQTMVMTSPVTLTSQTTKTDDPQLKREIRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYSHKSV
InterPro domains: - IPR004827: Basic-leucine zipper domain (domain) [208-265]
- IPR003102: Cyclic AMP-responsive element-binding protein 1-like, pKID (domain) [30-89]
- IPR046347: Basic-leucine zipper domain superfamily (homologous_superfamily) [211-263]
- IPR001630: cAMP response element binding (CREB) protein (family) [21-266]
Interaction partners: - Histone lysine acetyltransferase CREBBP
- Cyclic AMP-responsive element-binding protein 3-like protein 1
- Cyclic AMP-dependent transcription factor ATF-2
- Cyclic AMP-responsive element-binding protein 3-like protein 2
- Cyclic AMP-responsive element-binding protein 3-like protein 3
- Cyclic AMP-responsive element-binding protein 3-like protein 4
- Cyclic AMP-responsive element-binding protein 1
- non-specific serine/threonine protein kinase
- cAMP responsive element binding protein 5
- Cyclic AMP-dependent transcription factor ATF-4
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0044877 (protein-containing complex binding), GO:0097159 (organic cyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0042221 (response to chemical), GO:0048522 (positive regulation of cellular process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0010035 (response to inorganic substance), GO:0044085 (cellular component biogenesis), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0016043 (cellular component organization), GO:0031323 (regulation of cellular metabolic process), GO:0051130 (positive regulation of cellular component organization), GO:0080090 (regulation of primary metabolic process), GO:0051128 (regulation of cellular component organization), GO:0010033 (response to organic substance), GO:0009891 (positive regulation of biosynthetic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0010038 (response to metal ion), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0031344 (regulation of cell projection organization), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0031346 (positive regulation of cell projection organization), GO:0051052 (regulation of DNA metabolic process), GO:0051054 (positive regulation of DNA metabolic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0043933 (protein-containing complex organization), GO:0014070 (response to organic cyclic compound), GO:0051252 (regulation of RNA metabolic process), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0010468 (regulation of gene expression), GO:0022607 (cellular component assembly), GO:0006275 (regulation of DNA replication), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0032025 (response to cobalt ion), GO:1902680 (positive regulation of RNA biosynthetic process), GO:0065003 (protein-containing complex assembly), GO:0045740 (positive regulation of DNA replication), GO:2001141 (regulation of RNA biosynthetic process), GO:0010976 (positive regulation of neuron projection development), GO:0006355 (regulation of DNA-templated transcription), GO:0006357 (regulation of transcription by RNA polymerase II), GO:0045893 (positive regulation of DNA-templated transcription), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0010975 (regulation of neuron projection development), GO:0045944 (positive regulation of transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005667 (transcription regulator complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)