Protein: LD29223p (PAR-6) (Par-6, isoform B) (O97111)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Cell junction, tight junction {ECO:0000256|ARBA:ARBA00004435}. Cell membrane {ECO:0000256|ARBA:ARBA00004236}. Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Sequence: MSKNKINTTSATAASDTNLIEVKSKFDAEFRRWSFKRNEAEQSFDKFASLIEQLHKLTNIQFLILYIDPRDNDLLPINNDDNFGRALKTARPLLRVIVQRKDDLNEYSGFGTMKPRNLIGSILMGHTPVKTKAPSISIPHDFRQVSAIIDVDIVPETHRRVRLLKHGSDKPLGFYIRDGTSVRVTASGLEKQPGIFISRLVPGGLAESTGLLAVNDEVIEVNGIEVAGKTLDQVTDMMVANSSNLIITVKPANQRTLTSTHRGSFSRNSQLSSGSHHTNNTNTSDEIEHDDQDDIVDLTGVTLDESPTSTSAGNHNHQPPLSSSPSSHHQQAASNASTIMASDVKDGVLHL
InterPro domains: - IPR036034: PDZ superfamily (homologous_superfamily) [130-256]
- IPR051741: Partitioning defective 6 homolog protein (family) [9-257]
- IPR053793: PB1-like domain (domain) [19-101]
- IPR000270: PB1 domain (domain) [19-101]
- IPR034868: Partitioning defective protein 6, PB1 domain (domain) [20-101]
- IPR001478: PDZ domain (domain) [160-253]
Interaction partners: - Cdc42 homolog
- Bazooka, isoform B
- Atypical protein kinase C
- Protein crumbs
- Patj homolog
- Lethal
- Protein PALS1
- Protein lin-7 homolog
- Inscuteable
- Ras-related protein Rac1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0051641 (cellular localization), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0007163 (establishment or maintenance of cell polarity), GO:0071840 (cellular component organization or biogenesis), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0048609 (multicellular organismal reproductive process), GO:0033036 (macromolecule localization), GO:0007276 (gamete generation), GO:0030707 (follicle cell of egg chamber development), GO:0007281 (germ cell development), GO:0048729 (tissue morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0044085 (cellular component biogenesis), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0061245 (establishment or maintenance of bipolar cell polarity), GO:0070727 (cellular macromolecule localization), GO:0016332 (establishment or maintenance of polarity of embryonic epithelium), GO:0009790 (embryo development), GO:0016043 (cellular component organization), GO:0042335 (cuticle development), GO:0040003 (chitin-based cuticle development), GO:0010927 (cellular component assembly involved in morphogenesis), GO:0007292 (female gamete generation), GO:0002064 (epithelial cell development), GO:0035088 (establishment or maintenance of apical/basal cell polarity), GO:0048477 (oogenesis), GO:0002009 (morphogenesis of an epithelium), GO:0008104 (protein localization), GO:0060429 (epithelium development), GO:0016331 (morphogenesis of embryonic epithelium), GO:0034330 (cell junction organization), GO:0030855 (epithelial cell differentiation), GO:0022607 (cellular component assembly), GO:0045197 (establishment or maintenance of epithelial cell apical/basal polarity), GO:0045216 (cell-cell junction organization), GO:0034329 (cell junction assembly), GO:0007043 (cell-cell junction assembly), GO:0034332 (adherens junction organization), GO:0043297 (apical junction assembly), GO:0034333 (adherens junction assembly), GO:0045186 (zonula adherens assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0045177 (apical part of cell), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0098590 (plasma membrane region), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0016324 (apical plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)