Protein: 2'-5' oligoadenylate synthetase 1H (E9Q326)
Organism: Mus musculus (Mouse)
Function: Not known
Sequence: MAKNLSSTRIALCSTPAWRLDKFIEGHLLGDITFLTELRTDVNSISAFLKERCFQGAAHPMRVSRVVMGGSYNRYTVLKGRSEVDLLVFFNNLTCFDDQFKLQKEVIEEIQKHLCQFQQEKRLREKFKVQSSDQPNFRSVSFKLSYPKFQQEVEFHMQTAYDALYEVRRKENHNCEIYNKVYARLIRECTMLGKEGEFNICFMELQQDFLWKRPCELKNLICLVKHWYQLPDKKGFVFL
InterPro domains: - IPR002934: Polymerase, nucleotidyl transferase domain (domain) [57-130]
- IPR043519: Nucleotidyltransferase superfamily (homologous_superfamily) [10-213]
- IPR006116: 2-5OAS/ClassI-CCAase, nucleotidyltransferase domain (domain) [34-164]
- IPR018952: 2'-5'-oligoadenylate synthetase 1, domain 2/C-terminal (domain) [179-233]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003725 (double-stranded RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048523 (negative regulation of cellular process), GO:0048609 (multicellular organismal reproductive process), GO:0009892 (negative regulation of metabolic process), GO:0007276 (gamete generation), GO:0007281 (germ cell development), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0009994 (oocyte differentiation), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0007292 (female gamete generation), GO:0051246 (regulation of protein metabolic process), GO:0048599 (oocyte development), GO:0051248 (negative regulation of protein metabolic process), GO:0048477 (oogenesis), GO:0031061 (negative regulation of histone methylation), GO:0031060 (regulation of histone methylation), GO:0031399 (regulation of protein modification process), GO:0031400 (negative regulation of protein modification process), GO:0061085 (regulation of histone H3-K27 methylation), GO:0031057 (negative regulation of histone modification), GO:0031056 (regulation of histone modification)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)