Protein: FI04457p (GRIP and coiled-coil domain containing 185 kDa) (Q9VGE4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Sequence: MEAASPRETQKNPNPIEALSKDEIISKYKGLLNIAKKAKQAKDELTEENHRLKDALKRAAEKQSSLPAMQEMVQDFTDKNLILTEEVNNLKRKTKEDADRLTQFEIENESLKRQLGRLSDENDALLANVDRMEKAMQQVNALGNEQRKNLELLEVDIAKIKEAEAENASLRQQVATMEEESSVLQQKYQNIKELNSEQRKKFNSLKDRFIDVHRKLKNLKECKCVLLETQHEYAASVSKWQVEIIKASQLLCAKMASLQAENEKLKLNNGKSDNNPQTIDTGIDRKRLLQRVQEMDRLAKIVKQKQKNQRSNLNVEYLLKKITALEELAVIIKQQHRIDKEQLISVTKEQENTKNHARNLNVSLFQTKLDQMQNLVKVIAKERDNQQRKLQELEAICIELRQHNEDLLTRYHLKEQEHGELLTEMRELNEALKGRGDAISRLQEQHEAEVKRQRDLEAQLSNSQQAAQEKLQKIKQLQSRVEELEQANADAQSDVLSTSTISRAEELSRLRELDEGYEEKYHKLRAIAAKLKKKLQEQTQQLNEMEQSGALKEELEAIKLAQAQLQQDLNAARAENQKLKSKEKVKHSSVLNLEIEAAEKSLSEVSAKLTAKSSELEAVKESLASKENTIVQLRKEIAILEEAKNGEAAHSLELKEQIDRMQVQVKDAVHSKQQALTQNKDLEHGVEQAKLEAEQLRLQLSESAQQYESKLNTATQQLLSQTQELEMHLAEQKRLETALRNAERALEDLRVEYTEYKLKAQSVLRKNQNKGSNREQELEEELVALRESERNLRASNDGRAARLAQLDSQIEELRQDNTDLQKRSKELVSLVDELRQQNDLLSLENQRQLQFQHDLMQQHRQQVDELDAGHQLQLTQVQEQLEEAQKMQANVSQHTTASAASVDTSPEQAKIDYLLMDHETGLDGHAGDVSLAQLAAQRKISTASRRSHDFMPLDELLNTSMNQITSDTVTTISNFGRSVSQQEDEEAEMAARGDFSVQSAQLQATKERLSIQESRVKHLTALLAENEQDLAKLTQMNDMLKEELRRQERSEEREQHMHNSEYLKNVFLKFLTLNNVDERQRLVPVLNTILRLSRNEMEMLNCVAKGQKVSADGSSRSWTGFLTAWSGGGSPNNNN
InterPro domains: - IPR000237: GRIP domain (domain) [1053-1103]
- IPR051841: Microtubule and Golgi organization protein (family) [39-1112]
Interaction partners: - Syntaxin 16
- Ras-related protein Rab6
- GRIP and coiled-coil domain containing 88 kDa
- Ran GTPase-activating protein
- ADP-ribosylation factor-like protein 1
- Probable nucleoporin Nup54
- Ras-related protein Rab-2
- LD27967p
- GTP-binding nuclear protein Ran-like
- GTP-binding nuclear protein Ran
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0023052 (signaling), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0022414 (reproductive process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0048519 (negative regulation of biological process), GO:0009605 (response to external stimulus), GO:0019953 (sexual reproduction), GO:0051641 (cellular localization), GO:0048856 (anatomical structure development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0042221 (response to chemical), GO:0051240 (positive regulation of multicellular organismal process), GO:0007389 (pattern specification process), GO:0071840 (cellular component organization or biogenesis), GO:0051239 (regulation of multicellular organismal process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0051050 (positive regulation of transport), GO:0007267 (cell-cell signaling), GO:0065008 (regulation of biological quality), GO:0050793 (regulation of developmental process), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0009607 (response to biotic stimulus), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0051707 (response to other organism), GO:0007165 (signal transduction), GO:0048869 (cellular developmental process), GO:0023056 (positive regulation of signaling), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0032879 (regulation of localization), GO:0051234 (establishment of localization), GO:0009893 (positive regulation of metabolic process), GO:0006950 (response to stress), GO:0140352 (export from cell), GO:0007017 (microtubule-based process), GO:0048609 (multicellular organismal reproductive process), GO:0007154 (cell communication), GO:0048522 (positive regulation of cellular process), GO:0032989 (cellular component morphogenesis), GO:0051047 (positive regulation of secretion), GO:0044085 (cellular component biogenesis), GO:0043207 (response to external biotic stimulus), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0071495 (cellular response to endogenous stimulus), GO:0060255 (regulation of macromolecule metabolic process), GO:0007308 (oocyte construction), GO:0060627 (regulation of vesicle-mediated transport), GO:0050803 (regulation of synapse structure or activity), GO:0030317 (flagellated sperm motility), GO:0044089 (positive regulation of cellular component biogenesis), GO:0044087 (regulation of cellular component biogenesis), GO:0000902 (cell morphogenesis), GO:0009887 (animal organ morphogenesis), GO:0046907 (intracellular transport), GO:0050806 (positive regulation of synaptic transmission), GO:0051656 (establishment of organelle localization), GO:0048469 (cell maturation), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0032940 (secretion by cell), GO:0016043 (cellular component organization), GO:0009790 (embryo development), GO:0030952 (establishment or maintenance of cytoskeleton polarity), GO:0009994 (oocyte differentiation), GO:0051128 (regulation of cellular component organization), GO:0051962 (positive regulation of nervous system development), GO:0007297 (follicle cell of egg chamber migration), GO:0016477 (cell migration), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0007276 (gamete generation), GO:0007281 (germ cell development), GO:1903530 (regulation of secretion by cell), GO:0051049 (regulation of transport), GO:0007349 (cellularization), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0060341 (regulation of cellular localization), GO:0048515 (spermatid differentiation), GO:0051649 (establishment of localization in cell), GO:0001505 (regulation of neurotransmitter levels), GO:0051130 (positive regulation of cellular component organization), GO:0000226 (microtubule cytoskeleton organization), GO:0007317 (regulation of pole plasm oskar mRNA localization), GO:0030036 (actin cytoskeleton organization), GO:0007283 (spermatogenesis), GO:0098542 (defense response to other organism), GO:0007018 (microtubule-based movement), GO:0045165 (cell fate commitment), GO:0001709 (cell fate determination), GO:2000026 (regulation of multicellular organismal development), GO:0003002 (regionalization), GO:0010646 (regulation of cell communication), GO:0031325 (positive regulation of cellular metabolic process), GO:0016358 (dendrite development), GO:0006810 (transport), GO:0001539 (cilium or flagellum-dependent cell motility), GO:0010647 (positive regulation of cell communication), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0045807 (positive regulation of endocytosis), GO:1903532 (positive regulation of secretion by cell), GO:0030030 (cell projection organization), GO:0046928 (regulation of neurotransmitter secretion), GO:0050807 (regulation of synapse organization), GO:0051246 (regulation of protein metabolic process), GO:0048880 (sensory system development), GO:0032990 (cell part morphogenesis), GO:0090596 (sensory organ morphogenesis), GO:0007369 (gastrulation), GO:0050769 (positive regulation of neurogenesis), GO:0048260 (positive regulation of receptor-mediated endocytosis), GO:0007298 (border follicle cell migration), GO:0051650 (establishment of vesicle localization), GO:0099111 (microtubule-based transport), GO:0048666 (neuron development), GO:0022607 (cellular component assembly), GO:0000904 (cell morphogenesis involved in differentiation), GO:0007399 (nervous system development), GO:0030706 (germarium-derived oocyte differentiation), GO:0007292 (female gamete generation), GO:1902117 (positive regulation of organelle assembly), GO:0048813 (dendrite morphogenesis), GO:0009953 (dorsal/ventral pattern formation), GO:0048858 (cell projection morphogenesis), GO:1901890 (positive regulation of cell junction assembly), GO:0030100 (regulation of endocytosis), GO:0061458 (reproductive system development), GO:0035282 (segmentation), GO:0098813 (nuclear chromosome segregation), GO:0007167 (enzyme-linked receptor protein signaling pathway), GO:0031344 (regulation of cell projection organization), GO:0007423 (sensory organ development), GO:0048477 (oogenesis), GO:0017157 (regulation of exocytosis), GO:0046903 (secretion), GO:0032880 (regulation of protein localization), GO:0051960 (regulation of nervous system development), GO:0045921 (positive regulation of exocytosis), GO:1902115 (regulation of organelle assembly), GO:0022008 (neurogenesis), GO:0050770 (regulation of axonogenesis), GO:0016197 (endosomal transport), GO:0051965 (positive regulation of synapse assembly), GO:0031346 (positive regulation of cell projection organization), GO:0051247 (positive regulation of protein metabolic process), GO:0033043 (regulation of organelle organization), GO:0051046 (regulation of secretion), GO:0016192 (vesicle-mediated transport), GO:0009950 (dorsal/ventral axis specification), GO:0006996 (organelle organization), GO:0048232 (male gamete generation), GO:0010638 (positive regulation of organelle organization), GO:0030182 (neuron differentiation), GO:0051174 (regulation of phosphorus metabolic process), GO:0009952 (anterior/posterior pattern specification), GO:0048592 (eye morphogenesis), GO:0046552 (photoreceptor cell fate commitment), GO:0045937 (positive regulation of phosphate metabolic process), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0150063 (visual system development), GO:1904396 (regulation of neuromuscular junction development), GO:0042461 (photoreceptor cell development), GO:0051963 (regulation of synapse assembly), GO:0098916 (anterograde trans-synaptic signaling), GO:0042052 (rhabdomere development), GO:0048699 (generation of neurons), GO:0051028 (mRNA transport), GO:0048675 (axon extension), GO:0031401 (positive regulation of protein modification process), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0001654 (eye development), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0031399 (regulation of protein modification process), GO:0046530 (photoreceptor cell differentiation), GO:0120036 (plasma membrane bounded cell projection organization), GO:0048285 (organelle fission), GO:0019220 (regulation of phosphate metabolic process), GO:0035220 (wing disc development), GO:0007435 (salivary gland morphogenesis), GO:0031175 (neuron projection development), GO:0047496 (vesicle transport along microtubule), GO:0001738 (morphogenesis of a polarized epithelium), GO:0001932 (regulation of protein phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0031984 (organelle subcompartment), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0031090 (organelle membrane), GO:0005794 (Golgi apparatus), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098791 (Golgi apparatus subcompartment), GO:0098827 (endoplasmic reticulum subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0005789 (endoplasmic reticulum membrane), GO:0005795 (Golgi stack), GO:0098588 (bounding membrane of organelle), GO:0000139 (Golgi membrane), GO:0000137 (Golgi cis cisterna)