wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Isoliquiritigenin 2'-O-methyltransferase (MsCHMT) (EC 2.1.1.154) (Chalcone O-methyltransferase) (ChOMT) (Licodione 2'-O-methyltransferase) (MsLMT) (EC 2.1.1.65) (P93324)
Organism: Medicago sativa (Alfalfa)
Function: Methylates the 2'-hydroxyl of isoliquiritigenin and licodione. Does not methylate narigenin chalcone, caffeic acid or daidzein. Involved in the root nodulation initiation by promoting the biosynthesis of nod-inducing molecules.
Sequence: MGNSYITKEDNQISATSEQTEDSACLSAMVLTTNLVYPAVLNAAIDLNLFEIIAKATPPGAFMSPSEIASKLPASTQHSDLPNRLDRMLRLLASYSVLTSTTRTIEDGGAERVYGLSMVGKYLVPDESRGYLASFTTFLCYPALLQVWMNFKEAVVDEDIDLFKNVHGVTKYEFMGKDKKMNQIFNKSMVDVCATEMKRMLEIYTGFEGISTLVDVGGGSGRNLELIISKYPLIKGINFDLPQVIENAPPLSGIEHVGGDMFASVPQGDAMILKAVCHNWSDEKCIEFLSNCHKALSPNGKVIIVEFILPEEPNTSEESKLVSTLDNLMFITVGGRERTEKQYEKLSKLSGFSKFQVACRAFNSLGVMEFYK
InterPro domains: - IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [21-127]
- IPR012967: O-methyltransferase, dimerisation domain (domain) [21-125]
- IPR029063: S-adenosyl-L-methionine-dependent methyltransferase superfamily (homologous_superfamily) [130-369]
- IPR001077: O-methyltransferase, C-terminal domain (domain) [148-353]
- IPR016461: O-methyltransferase-like (family) [5-372]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [36-200]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0008168 (methyltransferase activity), GO:0008757 (S-adenosylmethionine-dependent methyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0019748 (secondary metabolic process), GO:0071704 (organic substance metabolic process), GO:0044550 (secondary metabolite biosynthetic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0009698 (phenylpropanoid metabolic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0019438 (aromatic compound biosynthetic process), GO:0009699 (phenylpropanoid biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Periplasmic nitrate reductase, electron transfer subunit (Diheme cytochrome c NapB) (P0ABL3)
Organism: Escherichia coli (strain K12)
Function: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from the membrane-anchored tetraheme c-type NapC protein and transfers these to NapA subunit, thus allowing electron flow between membrane and periplasm. Essential for periplasmic nitrate reduction with nitrate as the terminal electron acceptor.
Subcellular location: Periplasm {ECO:0000269|PubMed:10234835, ECO:0000269|PubMed:10548535, ECO:0000269|PubMed:17130127}.
Sequence: MKSHDLKKALCQWTAMLALVVSGAVWAANGVDFSQSPEVSGTQEGAIRMPKEQDRMPLNYVNQPPMIPHSVEGYQVTTNTNRCLQCHGVESYRTTGAPRISPTHFMDSDGKVGAEVAPRRYFCLQCHVPQADTAPIVGNTFTPSKGYGK
InterPro domains: - IPR005591: Nitrate reductase cytochrome c-type subunit NapB (family) [3-149]
- IPR036280: Multiheme cytochrome superfamily (homologous_superfamily) [48-145]
Interaction partners: - Ferredoxin-type protein NapG
- Cytochrome c-type protein NapC
- Ferredoxin-type protein NapH
- Periplasmic nitrate reductase
- Chaperone NapD
- Ferredoxin-type protein NapF
- Cytochrome c-552
- Cytochrome c-type protein TorC
- Nitrite reductase small subunit
- Respiratory nitrate reductase 1 alpha chain
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0016491 (oxidoreductase activity), GO:0009055 (electron transfer activity), GO:0046906 (tetrapyrrole binding), GO:0020037 (heme binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006091 (generation of precursor metabolites and energy), GO:0015980 (energy derivation by oxidation of organic compounds), GO:0022900 (electron transport chain), GO:0022904 (respiratory electron transport chain), GO:0045333 (cellular respiration), GO:0019645 (anaerobic electron transport chain), GO:0009061 (anaerobic respiration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0031975 (envelope), GO:0016020 (membrane), GO:1902494 (catalytic complex), GO:0071944 (cell periphery), GO:0070469 (respirasome), GO:0098796 (membrane protein complex), GO:1990351 (transporter complex), GO:0098797 (plasma membrane protein complex), GO:1902495 (transmembrane transporter complex), GO:0098803 (respiratory chain complex), GO:0070470 (plasma membrane respirasome), GO:1990204 (oxidoreductase complex), GO:0030964 (NADH dehydrogenase complex), GO:0005886 (plasma membrane), GO:0045271 (respiratory chain complex I)
Protein: C-C motif chemokine 1 (P500) (SIS-epsilon) (Small-inducible cytokine A1) (T-cell activation protein 3) (TCA-3) (TCA3) (P10146)
Organism: Mus musculus (Mouse)
Function: Cytokine that is chemotactic for neutrophils.
Sequence: MKPTAMALMCLLLAAVWIQDVDSKSMLTVSNSCCLNTLKKELPLKFIQCYRKMGSSCPDPPAVVFRLNKGRESCASTNKTWVQNHLKKVNPC
InterPro domains: - IPR039809: Chemokine beta/gamma/delta (family) [6-89]
- IPR000827: CC chemokine, conserved site (conserved_site) [33-75]
- IPR036048: Chemokine interleukin-8-like superfamily (homologous_superfamily) [27-89]
- IPR001811: Chemokine interleukin-8-like domain (domain) [30-89]
Interaction partners: - C-C chemokine receptor type 8
- C-C chemokine receptor type 5
- C-C chemokine receptor type 6
- C-C chemokine receptor type 1
- C-X-C motif chemokine 9
- Atypical chemokine receptor 4
- C-C chemokine receptor type 2
- C-X-C motif chemokine 10
- C-C chemokine receptor type 10
- Probable C-C chemokine receptor type 3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0005126 (cytokine receptor binding), GO:0001664 (G protein-coupled receptor binding), GO:0042379 (chemokine receptor binding), GO:0048020 (CCR chemokine receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0050793 (regulation of developmental process), GO:0019222 (regulation of metabolic process), GO:0009607 (response to biotic stimulus), GO:0051240 (positive regulation of multicellular organismal process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0051239 (regulation of multicellular organismal process), GO:0006950 (response to stress), GO:0051707 (response to other organism), GO:0048522 (positive regulation of cellular process), GO:0043207 (response to external biotic stimulus), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0006952 (defense response), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0001819 (positive regulation of cytokine production), GO:0001817 (regulation of cytokine production), GO:0009615 (response to virus), GO:0098542 (defense response to other organism), GO:0140546 (defense response to symbiont), GO:0032481 (positive regulation of type I interferon production), GO:0051607 (defense response to virus), GO:0010628 (positive regulation of gene expression), GO:0010468 (regulation of gene expression), GO:0032479 (regulation of type I interferon production)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Chaperone protein DNAJ, putative (Q57VU5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MSDSGDEYERREDILLQDDINLAGANVNGVDTDPCGYYASLGVSQDSSQAAIRRAFLQLSQIFHTDKHVGEDEEIQALMNERFQQLMEAYSVLSDEGKRAAYDASGKLGLNRYSLIPKEITQREDILRYMSTLEREAELLKLSKLLSASSRTTVSYSVDHLTNSMWKLGTSANDTLQQQSNGVDTEEAGTDEGETETPPKGDIADAANGAEGSSAQPVPLNTSVAVREVQLDGKNLLVLIPGDEVQQQLRQQLQHSTGGGSGGSAAPLSPEQRFGGVPLAAKLLLGLLPRKLHFEHSIHHYASPSFSVRTKTEAQHEGMRSVLRCTAIASYQPNPVTLYSISWRLSVARLHIACTWERILNNLWRLKSKLVLFNTQSLLPMYELSLKRMLAAGLEIENTWVMSMRNRGLFRTTIGQSTPEGAQRGLQFLVGYRSANVSLFSTAPVVWGGGEPGCGGVSRGVLEHSVSVDALRGRAHVGFSSWYTISKYNRIGVGFSTALPCPRGLSRYVSPFVDHPEYLSINEMSFLLGRGDHLIRIPVVVFHSPKVQSALLWLTAPVLLYRIGRLVMRPYQSARMAALYRQNRLDHRTEMDVARVRATHEQKALQSSSLRSRMAEEQIGGLVIINARYGVLQPRYPESLVLPPKQPNAAGNRSEVSGRQRQTWWRFWRAGRGTPTPSESVTVNGKKKDEGEETEGDSSSSVLVLDVTVPLQNFVRDSQLVLPEGSKSKLVGFTDPDPFTRERKQLKIVYRFQRRRHVVILDDEDIVRLPQREHLVES
InterPro domains: - IPR024586: DnaJ-like protein C11, C-terminal (domain) [583-770]
- IPR036869: Chaperone J-domain superfamily (homologous_superfamily) [23-120]
- IPR001623: DnaJ domain (domain) [36-117]
- IPR052243: Mitochondrial inner membrane organizing protein (family) [23-777]
- IPR018253: DnaJ domain, conserved site (conserved_site) [83-102]
Interaction partners: - Heat shock 70 kDa protein, putative
- Heat shock 70 kDa protein, mitochondrial, putative
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Semaphorin-3D (Semaphorin-2) (Semaphorin-Z2) (Sema Z2) (Q9W6G6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: May play a role in the guidance of several axon pathways.
Subcellular location: Secreted {ECO:0000250}.
Sequence: MKTAGEPDRRRQRRQVRTGRFSCAWWSTSVMLFFSLPEGNCMKESLPRVKLGYKDLIHSRSVVPFTGSSEGQHFQTVLLDEERSRLLLGAKDHVYLLDPDNINKHPKKLSWPASRDRVEMCILAGKNPLTECANFIRVLHSYNRTHVYACGTGAFHPTCAFLEIKGHKEDRWLLLHSNTMESGRMKCPFDPNQPFASVLTDQYLYAGTASDFLGKDSTFTRSLGPPPHQQYIRTDISEDYWINEGKFISAHPISDTYNPDDDKIYFFFREASRDGSTTDKSVLSRVARICRNDVGGLRSLTNKWTTFLKARLVCSIPGPDGVDTHFDELQDIFLLPSRDEKNPMVYGVFTTTSSIFKGSAVCVYTMEDIRAAFNGPYAHKEGPDHRWVEYEGRIPYPRPGTCPSRTYDPHIKTTKDFPDEVISFIRLHPLMYQSVHPMTGRPIFTRINTEYRLTQIIVDRVAAEDGQYAVMFLGTDMGSVLKVVSITQENWSSEEIILEELQVFKNPSPILNMEVSSKQQQLFVGGSDGLVQVSLHRCQIYGQGCAECCLARDPYCAWDGTQCSRYIPASKRRARRQDIKHGDPSSHCWDTEDVLGRNVEEKVLYGVESNSSFLECVSKSQQALIRWFVLKPGVDHRQEIKPDERVLITDRGLLIRWLQRGDAGSYFCTSQEHRFTRTLLHVSLHILDRGQINAHQPAIRESSENPAVTEPRQRYKDYLRMLSGPARSLDEYCETMWHREKKQKQKGKWKHVQELRKSRNRRHH
InterPro domains: - IPR016201: PSI domain (domain) [537-589]
- IPR036352: Sema domain superfamily (homologous_superfamily) [47-541]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [600-686]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [43-539]
- IPR001627: Sema domain (domain) [48-535]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [605-688]
- IPR042582: Semaphorin-3D, Sema domain (domain) [65-538]
- IPR027231: Semaphorin (family) [42-737]
Interaction partners: - Neuropilin-1a
- Neuropilin
- Plexin A3
- T-box transcription factor 18.
- Neuropilin
- Neuropilin 1b.
- Plexin D1.
- Plexin-A2
- Transcription factor 21
- Dihydropyrimidinase-related protein 3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0035239 (tube morphogenesis), GO:0048514 (blood vessel morphogenesis), GO:0002040 (sprouting angiogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Aquaporin FA-CHIP (P50501)
Organism: Pelophylax lessonae (Pool frog) (Rana lessonae)
Function: Forms a water-specific channel.
Subcellular location: Membrane; Multi-pass membrane protein.
Sequence: MASEFKKKAFWRAVIAEFLAMILFVFISIGAALGFNFPIEEKANQTVGRSQDIVKVSLAFGISIATMAQSVGHVSGAHLNPAVTLGCLLSCQISILKAVMYIIAQCLGAVVATAILSGITSGLENNSLGLNGLSPGVSAGQGLGVEILVTFQLVLCVVAVTDRRRHDVSGSVPLAIGLSVALGHLIAIDYTGCGMNPARSFGSAVLTKNFTYHWIFWVGPMIGGAAAAIIYDFILAPRTSDLTDRMKVWTNGQVEEYELDGDDNTRVEMKPK
InterPro domains: - IPR022357: Major intrinsic protein, conserved site (conserved_site) [78-86]
- IPR000425: Major intrinsic protein (family) [4-234]
- IPR023274: Aquaporin 1 (family) [1-272]
- IPR023271: Aquaporin-like (homologous_superfamily) [1-251]
- IPR034294: Aquaporin transporter (family) [4-257]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0005515 (protein binding), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015267 (channel activity), GO:0005372 (water transmembrane transporter activity), GO:0015250 (water channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0021537 (telencephalon development), GO:0060322 (head development), GO:0030900 (forebrain development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0021591 (ventricular system development), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0045178 (basal part of cell), GO:0045177 (apical part of cell), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0009925 (basal plasma membrane), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0016324 (apical plasma membrane), GO:0016323 (basolateral plasma membrane)
Protein: Presenilin 1 (H0YM52)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Cell projection, growth cone {ECO:0000256|ARBA:ARBA00004624}. Early endosome membrane {ECO:0000256|ARBA:ARBA00004520}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004520}.
Sequence: MTELPAPLSYFQNAQMSEDNHLSNTNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQL
InterPro domains: - IPR002031: Peptidase A22A, presenilin 1 (family) [1-68]
- IPR001108: Peptidase A22A, presenilin (family) [36-108]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0016032 (viral process), GO:0051641 (cellular localization), GO:0048524 (positive regulation of viral process), GO:0046794 (transport of virus), GO:0019058 (viral life cycle), GO:0051234 (establishment of localization), GO:0051716 (cellular response to stimulus), GO:0050792 (regulation of viral process), GO:0006950 (response to stress), GO:0140352 (export from cell), GO:0051050 (positive regulation of transport), GO:0046755 (viral budding), GO:0051640 (organelle localization), GO:0009894 (regulation of catabolic process), GO:0051701 (biological process involved in interaction with host), GO:0044085 (cellular component biogenesis), GO:0046907 (intracellular transport), GO:0051656 (establishment of organelle localization), GO:0033554 (cellular response to stress), GO:0006810 (transport), GO:0051649 (establishment of localization in cell), GO:0032940 (secretion by cell), GO:0002443 (leukocyte mediated immunity), GO:0051648 (vesicle localization), GO:0030537 (larval behavior), GO:0046596 (regulation of viral entry into host cell), GO:0010970 (transport along microtubule), GO:0006887 (exocytosis), GO:0030705 (cytoskeleton-dependent intracellular transport), GO:0044000 (movement in host), GO:0046903 (secretion), GO:0016192 (vesicle-mediated transport), GO:0051650 (establishment of vesicle localization), GO:0099111 (microtubule-based transport), GO:0072384 (organelle transport along microtubule), GO:0022607 (cellular component assembly), GO:0047496 (vesicle transport along microtubule), GO:0099518 (vesicle cytoskeletal trafficking)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0012505 (endomembrane system), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0030054 (cell junction), GO:0005654 (nucleoplasm), GO:0005794 (Golgi apparatus), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: LP02983p (Q8MS96)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MITSCYVRDVTKHRELLQQDAISFIEDRLPKEKVKDFVKDESEVHKPSVLIMGLDSTSRINLRRAMPSVYKFVRQPGWFEMQGYNKVGDNTFPNLLAALTGDSEKGVGDYCDVTKPGCLDSLNFIWKRFKKANYTTAFAEDCSSISTFNYLKPGFVKQPTDYYLRPLLFAIEKQFKVTNDFGFAYCVGRHLSFSYVWDFGQQFIDRFLGRSPMFGFLWSNSFTHDYYEGATALDNLLWKYLKSFEESNLFQKSIVILMSDHGHRYNTLRRASTGYFEERMPMMFIYLPPWFRRKYPHLASNLGKNQNRLSSNYDVYMTLQHLLQLDSKSVDEFPDNLRARQCKSCQSLFFELPFNRTCQMAGIEEKWCCCQPTETITNSPHVSTIAEAIVQRMNEHLISHNLSDLCHNFTLDYVEKADRKTILSNGLRPADKNEQVYIIVFETVPKNPIFEATVRWNSRTQRLLHFDVEELSRLTSYKNDANCINRKNAKKYCICKDSLSRPS
InterPro domains: - IPR017850: Alkaline-phosphatase-like, core domain superfamily (homologous_superfamily) [32-341]
- IPR004245: Protein of unknown function DUF229 (family) [1-496]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0016298 (lipase activity), GO:0042578 (phosphoric ester hydrolase activity), GO:0008081 (phosphoric diester hydrolase activity), GO:0004620 (phospholipase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0000003 (reproduction), GO:0019953 (sexual reproduction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: DUF222 domain-containing protein (Q8NRW3)
Organism: Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / BCRC 11384 / CCUG 27702 / LMG 3730 / NBRC 12168 / NCIMB 10025 / NRRL B-2784 / 534)
Function: Not known
Sequence: MSITTHVQALTTALNAIDNHLASMLDHGVTPDQYKAIEPDLIALEHTINHHATIAAQTTALAERTNAAQSIGSTHLIDYLTTTFGLSKARAHHRINLAHSLYPIPKPNSGSGNGGNGGNPDGGPDGGDSGDDDSGDDDPDPEPDKPEDGKPDSDKPRRPRISAEKHAIITDELARLNPNTTPSAEELRNQALSQAIWRTPEDLRTWLRHQVTTANKNNPNPITAMKRRYLSVGKPDADNMVRISGLVPAATAALITANTAPLTKRGNLVDLPAAEDMRTRGQRHADALHHIMEIYNHGIVTPARGGTASIIISMTTDDLDEINHANSSGESLLNNLYPTNTGYSLNLAEIMNLIAAKYDFAVLLDGETGQPLNVNRMQRSANLTQRIALFASELVCSAPNCDRPQLECEVHHLDPWMRGGLTNLVNLTHQCFNHHPRNDDSRSGVNGKGFMDRDPATGRVGHYPVGGEGPVFNRSAAADRSGGAWARRKHHGPPPTPPDPPDPPGPEPDPGDEGRLF
InterPro domains: - IPR003870: Domain of unknown function DUF222 (domain) [169-390]
- IPR003615: HNH nuclease (domain) [385-435]
Interaction partners: - HNH nuclease domain-containing protein
- HNH nuclease domain-containing protein
- HNH nuclease domain-containing protein
- HNH nuclease domain-containing protein
- HNH domain-containing protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0006950 (response to stress), GO:0009991 (response to extracellular stimulus), GO:0071496 (cellular response to external stimulus), GO:0031668 (cellular response to extracellular stimulus), GO:0033554 (cellular response to stress), GO:0006974 (cellular response to DNA damage stimulus), GO:0009432 (SOS response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0140535 (intracellular protein-containing complex), GO:0030880 (RNA polymerase complex), GO:1990234 (transferase complex), GO:0000428 (DNA-directed RNA polymerase complex), GO:0061695 (transferase complex, transferring phosphorus-containing groups)