Protein: Protein borderless (Q9U4G1)
Organism: Drosophila melanogaster (Fruit fly)
Function: In the developing eye, has a role in axonal targeting of the R7 photoreceptor where it functions together with tutl. Probably mediates homotypic cell adhesion; the effect is inhibited by Lar.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000255}. Cell projection, axon {ECO:0000269|PubMed:24174674}.
Sequence: MPAKRSRTFRQSGSALLALLAIILLMNISCTSAARDHRRQTNLEAKVGSHVVFNCYIDFPFDAPIPYLVHWTKDNKKIFTWYEQETSTSELFNGRLHLVENHPEFGRASVNLTAIRESDQGWYHCQVSFPNRSPSVRNNGTAYHLAVQGGSLIRIPPVNQTIREGQTAFFHCVMKHPENSQASWYKDGVLLQEVQDLVRRFYMGPDGSLSIDPTMMSDLGEYECKVRNSDGELQTAKAFLNIQYKAKVIYAPPEVFLPYGQPAVLDCHFRANPPLKNLRWEKDGLLFDSYNVPGVFYKMNGSLFFAKVDENHAGSYTCTPYNDLGTDGPSPVISVIVLRPPIFSVTPKAIYIQKLGEAAELPCEAIDRDGNNRPSIIWGRKDGQPLPADRFSLSGGNLTITGLVEGDRGIYECSATNEAATITAEAELMIENIAPRAPYNLTANSTETCITIRWQPGYLRPNLEYTVWYRLMEAPEWRTLRVLDKKVMEATVQHLQPGKEYEFMVLSQDKYGDGMFSKQFRFQTLPSPIRADDFDAQQLQHDLGQVTAPAGGLGAPWNLTAISNQQGWLLHWEHPVQGLEGLRLYAVRWWKEPEHFLIGHAETFDNYYQLRHLKEDTLFKVQVLAVGTETQQSVPSHELLIDVPSQRKVRALIIGSSVGVIFLLCALCAFLYVKRSCLRHLFAKDSSASEDEDTAESGDCDSDEQDQRDRDSIKIRQST
InterPro domains: - IPR036116: Fibronectin type III superfamily (homologous_superfamily) [434-629]
- IPR013106: Immunoglobulin V-set domain (domain) [41-147]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [41-430]
- IPR003961: Fibronectin type III (domain) [434-646]
- IPR013098: Immunoglobulin I-set (domain) [154-241]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [37-528]
- IPR007110: Immunoglobulin-like domain (domain) [48-429]
- IPR003598: Immunoglobulin subtype 2 (domain) [46-420]
- IPR003599: Immunoglobulin domain subtype (domain) [40-431]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0042221 (response to chemical), GO:0042330 (taxis), GO:0071840 (cellular component organization or biogenesis), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0008037 (cell recognition), GO:0040012 (regulation of locomotion), GO:0032989 (cellular component morphogenesis), GO:0008038 (neuron recognition), GO:0048468 (cell development), GO:0050920 (regulation of chemotaxis), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0032101 (regulation of response to external stimulus), GO:0000902 (cell morphogenesis), GO:0016043 (cellular component organization), GO:0051128 (regulation of cellular component organization), GO:0006935 (chemotaxis), GO:0016477 (cell migration), GO:0030030 (cell projection organization), GO:0031344 (regulation of cell projection organization), GO:0097485 (neuron projection guidance), GO:0032990 (cell part morphogenesis), GO:1902667 (regulation of axon guidance), GO:0048666 (neuron development), GO:0022008 (neurogenesis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0007399 (nervous system development), GO:0008347 (glial cell migration), GO:0048813 (dendrite morphogenesis), GO:0048858 (cell projection morphogenesis), GO:0030182 (neuron differentiation), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0007411 (axon guidance), GO:0070983 (dendrite guidance), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0048812 (neuron projection morphogenesis), GO:0061564 (axon development), GO:0008045 (motor neuron axon guidance), GO:0007409 (axonogenesis), GO:0010975 (regulation of neuron projection development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)