Protein: MAM domain-containing glycosylphosphatidylinositol anchor 2a (A0A8M6YTC4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor
Sequence: MDIIWALLWLLAALFEGVFCQGVYAPPTVQIIHSGHACNIEEERYTERVYTIREGETLELTCLVSGHPRPQIRWTKTAGSATDRFQDSSVFNETLRITRIQRHQGGRYYCKAENGLGTPAIKSIRVDVYYLDDPIVTVHQSIGEAKEQFYYERTVFLRCAANSNPPVRYSWRRGREFLYQGSDKGVEIYEPFFTQGETKILKLKNLRPQDYANYTCTASVRSVCGIPDKSVLFQLTNKTASPTIKLLVEDPIVANPGQTVTLVCIISGGEPSPTLSWVRNTEELPKKSVLNGGTLTIPAISTDDAGVYSCVASNNVGNPAKKSTNIVVRALKKGRFWITPDPYHNDDNIQIGREVKISCQVEATPPEELMFSWLKNGRPLRSSERMVITQTDPDVAPGTTNLDIIDLKFTDFGTYTCVASLKNGGIPEISIDVNISSTTVPPNLTVPRGKSPLVTQEGDTVELQCLVSGKPKPIIIWSRADKEAPMPDGNMQTESYDGVLRIVNVSREMTGTYRCQTSQYNGFNVKPREAIVELIVQYPPAVEPVYTEIRQGLGRPFSLSCRVLRAHPSRVLKYEWKLGTRLLTMGQFDTRDETEYHVRALNREGYGAYTCDITNEAGAGRCTFLVTGKAFAPEFFYDTYSALWQNKPRVYGFKLQWTQMNPNAVDRIMAYRLGIKQMGHQRWWEQEIPTEDNIQKGELLSYNLTELIKPEAYQVRLTPITRFGEGDSTERIIRYSAPVNPHWSKFHCGFEEDTICMFTQDKTEEFDWTRHSAATRDTKYTPNTGPSSDRSGSKQGFYMYIETSRPRLEGDKARLLTPSFNVAPKNPYGNVASNPTYCFSFYYHMYGKHIGTLNVYLRQKSQTGQDTSVWTLSGNQGDRWRQARVNINPTSSFQIVMEGIRGSGIEGDIAVDDVTIEEGECRDPPPSSNIRSLASPTEVHIWQLALTLLLVLVGLRR
InterPro domains: - IPR013098: Immunoglobulin I-set (domain) [348-423]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [49-627]
- IPR050958: Cell Adhesion and Cytoskeletal Organization (family) [17-933]
- IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [744-921]
- IPR000998: MAM domain (domain) [743-923]
- IPR007110: Immunoglobulin-like domain (domain) [27-627]
- IPR003598: Immunoglobulin subtype 2 (domain) [53-522]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [654-733]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [43-734]
- IPR003599: Immunoglobulin domain subtype (domain) [47-629]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0050793 (regulation of developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0050794 (regulation of cellular process), GO:0051241 (negative regulation of multicellular organismal process), GO:0051239 (regulation of multicellular organismal process), GO:0051093 (negative regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:2000026 (regulation of multicellular organismal development), GO:0042127 (regulation of cell population proliferation), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0051961 (negative regulation of nervous system development), GO:0045596 (negative regulation of cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0045595 (regulation of cell differentiation), GO:0022008 (neurogenesis), GO:0050768 (negative regulation of neurogenesis), GO:0007399 (nervous system development), GO:0048880 (sensory system development), GO:0060284 (regulation of cell development), GO:0007423 (sensory organ development), GO:0010001 (glial cell differentiation), GO:0060253 (negative regulation of glial cell proliferation), GO:0051960 (regulation of nervous system development), GO:0010721 (negative regulation of cell development), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0014014 (negative regulation of gliogenesis), GO:0001654 (eye development), GO:0050767 (regulation of neurogenesis), GO:0048699 (generation of neurons), GO:0150063 (visual system development), GO:0043010 (camera-type eye development), GO:0014013 (regulation of gliogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)