Protein: WD repeat domain 62 (F6NPK9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MADGAVNFGASMNQSCLTSRAKKANNNSTSVPANTRRKTRQSHRRDIHNRVVLEKVLGITASSSSALTCDPNTGLVAYPAGCVIVILSPKKNKQTHIFNTSRKTFSALAFSQNGKYLVTGESGHMPCVRVWDVAERTQVAEVQCHKYGVSCVAFSPNGSYIVSVGYQHDRTVSVWEWKKGTVIASNKVSSRVLGVSFSEDNSYFVTAGNRHVKFWYLDASKERRVNSTVPLIGRSGLLGEHQNSQFCGLACGRGSMASSTYCITHTGLLCQFNSNRQLDSWVDLKTTSAQCLSVSGTFVFCGCADGTVRVFSPQDLRYITTLHRPHCLGVDVSQGTQPGHLFSANPEAQYPDTLALTFDPVTKHLTCVYNDHSVYVWDVRDIRNVGKVYSALYHSGCVWSVETYPELEDPSAACLSPGSFLTCSSDNTIRLWRSESPQSHSAALGLRHNLYSQDIVRIVYVDDDTQYLKAEAEKAEGGAGQDGKSGIRVLGISPDGQHLAAGDRSGNLRIFGLQFMDELQKIEAHDSEVLCLAFSPAETGLHLLASASRDRLIHIFDMDSKCNLVQTVYDHSASITAVKFTGLNSELCMVSCGADKSVYFRSAEKTSDGLVFSRSHHIVEKTTLYDMDLDATRTHTAIACQDRNIRVYNVKSGKMKKCFKGSMNDDGTLLKVQLDPSGMFLATSCSDKNICVFDYESGECVATLFGHSEIVTGMKFSQDCRHLITVSGDSCVFVWRLDSQMTNSMRKRLAERKQQAGLRLQRAPTKQEVIRRETYITVPCNALTHMEEDGLMAEVNPEDGLEDCRTPDRLDSTDASLDSVVLQTNGKMPMWVRRLGGEGEKDGTGAANRVQYQPQGRWAVQSDPLAIRTVLEMKSNQLPLSHTPSRVMGEEELEEDPRFHPQSLDSLLDEDLEDGEEEEEEKICGVSSDGFSSSLHGPEFLQFPHGEENFNPELSSSEKTGYILYPANSTALSTGEGEFDVKALCEGTAGDPDEEELSPDSACSAESPESHSDQPHDQDTDSLSQVSSTGSSGVEEDEEESGTLLRQHFDTLGVATNEKFNTDLSSLQPTTESNFLNPRLSISTRFLSRFQSRFRSAACRPAACLSSIPDESTDSQTLDQTMEKPKHLSNSGSVEEKEKTEITNKNQSTTQSTTSAPGVLSNKSTSNSCDASVTRSRQSYMGPTASSRAKINQSNSVESLNLCISEETPLNALPNVEHSKENMIPPSSPVVSSAPLHQSPVLGNHSARASLRLDLIGHNRASLSPVSLKSRRGKVEHHDSPRRQALVTPTEMRSLGKESRKQISNIEQSLAPSDRLSTGAGMFSRSPMVRQTSDTVFEDLQSVRSDQTSVSSPMTNAVSQDNQDSADNNSIPEETGLSAEALSVQMCKEMVNELWHTIHKATDLYSKLCSIPELSEQQEQMKGVLQEVFVGVQSELNSICPQKTQPSTKSTRPISEDSPGRQLRDDRAVALLEKYSEMLLLRMTEKGAQATLE
InterPro domains: - IPR056161: MABP1/WDR62, first WD40 domain (domain) [65-392]
- IPR011047: Quinoprotein alcohol dehydrogenase-like superfamily (homologous_superfamily) [80-741]
- IPR056162: MABP1/WDR62, second WD40 domain (domain) [398-737]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [264-437]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [62-774]
- IPR001680: WD40 repeat (repeat) [91-745]
- IPR055292: Mitogen-activated protein kinase-binding protein 1 (family) [14-1167]
Interaction partners: - Abnormal spindle-like microcephaly-associated protein
- Centrosomal P4.1-associated protein
- SCL-interrupting locus protein homolog
- Centrosomal protein of 63 kDa
- Centrosomal protein of 135 kDa
- Microcephalin 1
- Dual specificity mitogen-activated protein kinase kinase 7
- Serine/threonine-protein kinase PLK4
- Pericentrin
- Si:ch211-269m15.3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0050793 (regulation of developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0050794 (regulation of cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0032989 (cellular component morphogenesis), GO:0000902 (cell morphogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0045595 (regulation of cell differentiation), GO:0016043 (cellular component organization), GO:0032886 (regulation of microtubule-based process), GO:0051128 (regulation of cellular component organization), GO:0022008 (neurogenesis), GO:1902903 (regulation of supramolecular fiber organization), GO:0070507 (regulation of microtubule cytoskeleton organization), GO:0000904 (cell morphogenesis involved in differentiation), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0032990 (cell part morphogenesis), GO:0033043 (regulation of organelle organization), GO:0048858 (cell projection morphogenesis), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0051493 (regulation of cytoskeleton organization), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0031110 (regulation of microtubule polymerization or depolymerization), GO:0032271 (regulation of protein polymerization), GO:0031113 (regulation of microtubule polymerization), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0048812 (neuron projection morphogenesis), GO:0061564 (axon development), GO:0007409 (axonogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)