wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Lysozyme 3 (EC 3.2.1.17) (1,4-beta-N-acetylmuramidase 3) (Invertebrate-type lysozyme 3) (cv-lysozyme 3) (B3A003)
Organism: Crassostrea virginica (Eastern oyster)
Function: Has antibacterial activity against the Gram-negative bacterium E.coli. No antibacterial activity detected against the Gram-negative bacterium V.vulnificus.
Subcellular location: Secreted {ECO:0000250|UniProtKB:P83673}.
Sequence: MNGLFLFCVATTAALAYGSDAPCTNSGGVCQDDHLACHNGHYQSGLCTGGAHRRCCLTSASHTGSFSTGIVSQQCLQCICNVESGCKAIGCHFDVNSDSCGYFQIKEGYWHDCGSPGSSWRSCANDLACASKCVQAYMSRYIGFSGCSHSCESYARIHNGGPAGCKHTNTLGYWSHVHAQGCSHNSK
InterPro domains: - IPR023346: Lysozyme-like domain superfamily (homologous_superfamily) [71-160]
- IPR008597: Invertebrate-type lysozyme (family) [51-183]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0061783 (peptidoglycan muralytic activity), GO:0016787 (hydrolase activity), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0003796 (lysozyme activity), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0006950 (response to stress), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006952 (defense response), GO:0043207 (response to external biotic stimulus), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0042742 (defense response to bacterium), GO:0050829 (defense response to Gram-negative bacterium), GO:0050830 (defense response to Gram-positive bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase) (LAL) (EC 3.1.1.13) (Cholesteryl esterase) (Diacylglycerol lipase) (Lipase A) (Sterol esterase) (Triacylglycerol ester hydrolase) (Triacylglycerol lipase) (Q64194)
Organism: Rattus norvegicus (Rat)
Function: Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol.
Subcellular location: Lysosome {ECO:0000269|PubMed:4062953}.
Sequence: MQLLGRVICFVVGILLSGGPTGTISAVDPEANMNVTEIIMHWGYPEHSVQTGDGYILGVHRIPHGRKNQFDKGPKPVVYLQWRHGFLADSSNWVTNIDNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEYWAFSFDEMAKYDLPASINYILNKTGQEQLYNVGHSQGCTIGFIAFSQMPELAKKVKMFFALAPVLSLNFASGPMVKLGRLPDLLLEDLFGQKQFLPQSAMVKWLSTHICTHVIMKELCANIFFLICGFNEKNLNMSRVDVYTTHCPAGTSVQNMVHWTQVVKYHKLQAFDWGSSDKNYFHYNQSYPPLYSIKDMQLPTALWSGGKDWLADTSDINILLTEIPTLVYHKNIPEWDHLDFIWGLDAPWRLYNEVVSLMKKYQ
InterPro domains: - IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [22-395]
- IPR025483: Lipase, eukaryotic (family) [1-397]
- IPR000073: Alpha/beta hydrolase fold-1 (domain) [84-378]
Interaction partners: - 7-dehydrocholesterol reductase
- Bile salt-activated lipase
- Delta
- Sterol 26-hydroxylase, mitochondrial
- Cytochrome P450 7A1
- Cholesterol 25-hydroxylase
- Cholesterol 24-hydroxylase
- Cholesterol side-chain cleavage enzyme, mitochondrial
- Steryl-sulfatase
- Apolipoprotein B-100
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016491 (oxidoreductase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016298 (lipase activity), GO:0052689 (carboxylic ester hydrolase activity), GO:0016615 (malate dehydrogenase activity), GO:0004806 (triglyceride lipase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0044281 (small molecule metabolic process), GO:0007586 (digestion), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006082 (organic acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0043648 (dicarboxylic acid metabolic process), GO:0006108 (malate metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Retinol dehydrogenase 14 (All-trans and 9-cis), isoform CRA_a (cDNA, FLJ95921, Homo sapiens retinol dehydrogenase 14 (all-trans and 9-cis)(RDH14), mRNA) (Q53RX3)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MAVATAAAVLAALGGALWLAARRFVGPRVQRLRRGGDPGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPVEGAQTSIYLASSPEVEGVSGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGLLK
InterPro domains: - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [41-308]
- IPR002347: Short-chain dehydrogenase/reductase SDR (family) [44-292]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor), GO:0004033 (aldo-keto reductase (NADP) activity), GO:0008106 (alcohol dehydrogenase (NADP+) activity), GO:0052650 (NADP-retinol dehydrogenase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0001503 (ossification), GO:0030154 (cell differentiation), GO:0001649 (osteoblast differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005829 (cytosol), GO:0005654 (nucleoplasm), GO:0031984 (organelle subcompartment), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0043229 (intracellular organelle), GO:0098827 (endoplasmic reticulum subcompartment), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0005773 (vacuole), GO:0043233 (organelle lumen), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0005789 (endoplasmic reticulum membrane), GO:0005774 (vacuolar membrane), GO:0070013 (intracellular organelle lumen), GO:0005764 (lysosome), GO:0005634 (nucleus), GO:0031981 (nuclear lumen), GO:0098852 (lytic vacuole membrane), GO:0005765 (lysosomal membrane)
Protein: Claudin-5 (Q9JKD6)
Organism: Rattus norvegicus (Rat)
Function: Plays a major role in tight junction-specific obliteration of the intercellular space.
Subcellular location: Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Sequence: MGSAALEILGLVLCLVGWVGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYESVLALSAEVQAARALTVGAVLLALVALFVTLTGAQCTTCVAPGPVKARVALTGGALYALCGLLALVPLCWFANIVVREFYDPTVPVSQKYELGAALYIGWAASALLMCGGGLVCCGAWVCTGRPEFSFPVKYSAPRRTTANGDYDKKNYV
InterPro domains: - IPR017974: Claudin, conserved site (conserved_site) [49-64]
- IPR003551: Claudin-5 (family) [8-198]
- IPR006187: Claudin (family) [5-189]
- IPR004031: PMP-22/EMP/MP20/Claudin (family) [6-180]
Interaction partners: - Occludin
- Tight junction protein ZO-1
- Tight junction protein 2
- Endothelial cell-selective adhesion molecule
- SRY-box transcription factor 18
- Cadherin-5
- Junctional adhesion molecule A
- Tight junction protein 3
- Claudin-12
- Claudin-3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019904 (protein domain specific binding), GO:0050839 (cell adhesion molecule binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0009893 (positive regulation of metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0019222 (regulation of metabolic process), GO:0007155 (cell adhesion), GO:0009892 (negative regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0098609 (cell-cell adhesion), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0010628 (positive regulation of gene expression), GO:0034330 (cell junction organization), GO:0010629 (negative regulation of gene expression), GO:0010468 (regulation of gene expression), GO:0022607 (cellular component assembly), GO:0045216 (cell-cell junction organization), GO:0034329 (cell junction assembly), GO:0007043 (cell-cell junction assembly), GO:0120193 (tight junction organization), GO:0120192 (tight junction assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0005911 (cell-cell junction), GO:0043296 (apical junction complex), GO:0070160 (tight junction), GO:0005923 (bicellular tight junction)
Protein: Bacterioferritin-associated ferredoxin (Bfd) (Q9HY80)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Not known
Sequence: MYVCLCQGVTDNQIRDAIYEGCCSYREVREATGVGTQCGKCACLAKQVVRETLNDLQSAQPVPAFGTTAFVAA
InterPro domains: - IPR007419: BFD-like [2Fe-2S]-binding domain (domain) [2-50]
- IPR041854: BFD-like [2Fe-2S]-binding domain superfamily (homologous_superfamily) [1-56]
- IPR052371: Bacterioferritin-associated ferredoxin (family) [1-69]
Interaction partners: - Bacterioferritin BfrB
- Bacterial ferritin
- Ferredoxin--NADP reductase
- Protein TonB
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0051540 (metal cluster binding), GO:0016491 (oxidoreductase activity), GO:0051536 (iron-sulfur cluster binding), GO:0051537 (2 iron, 2 sulfur cluster binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006520 (amino acid metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006082 (organic acid metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0043436 (oxoacid metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0072522 (purine-containing compound biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0032993 (protein-DNA complex)
Protein: Phospholipase A2-beta (F4ITF6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Sequence: MMFRTSLMRFAAAFFAIVFVVLVGVARSEECTRTCIAQNCDTLSIRYGKYCGIGHSGCPGEEPCDDLDACCKIHDHCVELNGMTNISCHKKFQRCVNRLSKAIKQSKNKKVGFSTKCPYSVVIPTVNQGMDIGILFSQLAYHRKFVTD
InterPro domains: - IPR033113: Phospholipase A2, histidine active site (active_site) [70-77]
- IPR036444: Phospholipase A2 domain superfamily (homologous_superfamily) [19-146]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0016298 (lipase activity), GO:0052689 (carboxylic ester hydrolase activity), GO:0004623 (phospholipase A2 activity), GO:0004620 (phospholipase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0048589 (developmental growth), GO:0009856 (pollination), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0009628 (response to abiotic stimulus), GO:0044706 (multi-multicellular organism process), GO:0009653 (anatomical structure morphogenesis), GO:0016049 (cell growth), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0009846 (pollen germination), GO:0045927 (positive regulation of growth), GO:0003006 (developmental process involved in reproduction), GO:0040008 (regulation of growth), GO:0048522 (positive regulation of cellular process), GO:0000902 (cell morphogenesis), GO:0048588 (developmental cell growth), GO:0048468 (cell development), GO:0060560 (developmental growth involved in morphogenesis), GO:0030154 (cell differentiation), GO:0009826 (unidimensional cell growth), GO:0001558 (regulation of cell growth), GO:0009629 (response to gravity), GO:0009860 (pollen tube growth), GO:0048868 (pollen tube development), GO:0030307 (positive regulation of cell growth), GO:0051128 (regulation of cellular component organization), GO:0010033 (response to organic substance), GO:0009606 (tropism), GO:0009725 (response to hormone), GO:0009630 (gravitropism), GO:0000904 (cell morphogenesis involved in differentiation), GO:0009733 (response to auxin), GO:0009932 (cell tip growth)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Allantoicase (EC 3.5.3.4) (Allantoate amidinohydrolase) (P25335)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Utilization of purines as secondary nitrogen sources, when primary sources are limiting.
Sequence: MKFFSLADEAEFKSIIISKNKAVDVIGSKLGGQVVSFSDEWFASAENLIQPTAPIRDPTRFVHSGAWYDGWETRRHNEMEYDWVIIKMGVAAAHIIGGEIDTAFFNGNHAPFVSIEALYDEGEEGNIVEDDSRWVEIVEKFECGPSQRHLFVRGNGLTKERFTHIKLKMYPDGGIARFRLYGRVVPPELKTKDHIIDLAYVCNGAVALKYSDQHFGSVDNLLLPGRGHDMSDGWETKRSRQPGHTDWAVIQLGRESSFIEKIIVDTAHFRGNFPQFITVEGCLKESESSENTGEGTWVELVGKSKTGPDKEHVYEIRKSIRVSHVKLTIIPDGGVKRIRVWGY
InterPro domains: - IPR005164: Allantoicase (family) [1-343]
- IPR015908: Allantoicase domain (domain) [31-342]
- IPR008979: Galactose-binding-like domain superfamily (homologous_superfamily) [4-343]
Interaction partners: - Ureidoglycolate lyase
- Allantoinase
- Urea amidolyase
- Protein DAL82
- Allantoin permease
- Malate synthase 2
- Protein DCG1
- Nitrogen regulatory protein DAL80
- Transcriptional activator protein DAL81
- Urea active transporter
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0016813 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0071941 (nitrogen cycle metabolic process), GO:0019627 (urea metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0000050 (urea cycle), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Candida glabrata strain CBS138 chromosome K complete sequence (Q6FMP9)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Function: Not known
Sequence: MVAQVQKPAPTFKKTAVIDGMFEEVSLDKYKGKYVVLAFVPLAFTFVCPTEIVAFSEAAKRFEALDAQVLFASTDSEYSLLAWTNVARKDGGLGPVDIPLLADTNHKLSRDYGVLIEDEGIALRGLFIIDPKGIVRHITINDLPVGRNVEESLRLVEGFQWTDKNGTVLPCNWTPGSATIKPTVEDSKEYFKEANSKN
InterPro domains: - IPR024706: Peroxiredoxin, AhpC-type (family) [1-198]
- IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [4-194]
- IPR013766: Thioredoxin domain (domain) [3-161]
- IPR019479: Peroxiredoxin, C-terminal (domain) [158-192]
- IPR000866: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant (domain) [5-138]
- IPR050217: Thiol-specific antioxidant peroxiredoxin (family) [3-194]
Interaction partners: - Sulfiredoxin
- Thioredoxin reductase
- Candida glabrata strain CBS138 chromosome M complete sequence
- Thioredoxin
- Catalase
- Candida glabrata strain CBS138 chromosome E complete sequence
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0006979 (response to oxidative stress), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0034599 (cellular response to oxidative stress), GO:0062197 (cellular response to chemical stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Subtilisin-like protease SBT3.6 (EC 3.4.21.-) (Subtilase subfamily 3 member 6) (AtSBT3.6) (Q8L7I2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Secreted {ECO:0000250|UniProtKB:Q84WS0}.
Sequence: MMNYRTSIYVVLSLVIFLNVQRSFVAESSAKRKVHIVYLGEKQHDDPEFVTESHHRMLWSLLGSKEDANDSMVYSYRHGFSGFAAKLTESQAKKIADLPDVVHVIPDSFYKLATTRTWDYLGLSAANPKSLLHETNMGEQIIIGVIDTGVWPESEVFNDSGFGPVPSHWKGGCETGENFNSSNCNKKLIGAKYFINGFLAENESFNSTNSLDFISPRDLDGHGTHVSTIAGGSFVPNISYKGLAGGTVRGGAPRAHIAMYKACWYLDDDDTTTCSSADILKAMDEAMHDGVDVLSISLGSSVPLYGETDIRDGITTGAFHAVLKGITVVCSGGNSGPDSLTVTNTAPWIITVAATTLDRSFATPLTLGNNKVILGQAMYTGPGLGFTSLVYPENPGNSNESFSGTCEELLFNSNRTMEGKVVLCFTTSPYGGAVLSAARYVKRAGGLGVIIARHPGYAIQPCLDDFPCVAVDWELGTDILLYTRSSGSPVVKIQPSKTLVGQPVGTKVATFSSRGPNSIAPAILKPDIAAPGVSILAATTNTTFSDQGFIMLSGTSMAAPAISGVAALLKALHRDWSPAAIRSAIVTTAWKTDPFGEQIFAEGSPPKLADPFDYGGGLVNPEKSANPGLVYDMGLEDYVLYMCSVGYNETSISQLIGKTTVCSNPKPSVLDFNLPSITIPNLKDEVTITRTVTNVGPLNSVYRVTVEPPLGFQVTVTPETLVFNSTTKKVYFKVKVSTTHKTNTGYYFGSLTWSDSLHNVTIPLSVRTQILQNYYDEN
InterPro domains: - IPR015500: Peptidase S8, subtilisin-related (family) [138-569]
- IPR034197: Cucumisin-like catalytic domain (domain) [110-590]
- IPR010259: Peptidase S8 propeptide/proteinase inhibitor I9 (domain) [34-112]
- IPR023828: Peptidase S8, subtilisin, Ser-active site (active_site) [554-564]
- IPR000209: Peptidase S8/S53 domain (domain) [138-592]
- IPR041469: Subtilisin-like protease, fibronectin type-III domain (domain) [671-766]
- IPR036852: Peptidase S8/S53 domain superfamily (homologous_superfamily) [11-681]
- IPR037045: Peptidase S8 propeptide/proteinase inhibitor I9 superfamily (homologous_superfamily) [19-113]
- IPR045051: Subtilisin-like protease (family) [48-765]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0017171 (serine hydrolase activity), GO:0008233 (peptidase activity), GO:0008236 (serine-type peptidase activity), GO:0004175 (endopeptidase activity), GO:0004252 (serine-type endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0002376 (immune system process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0006950 (response to stress), GO:0051707 (response to other organism), GO:0006955 (immune response), GO:0009607 (response to biotic stimulus), GO:0006952 (defense response), GO:0043207 (response to external biotic stimulus), GO:0045087 (innate immune response), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0009682 (induced systemic resistance), GO:0042742 (defense response to bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0005618 (cell wall), GO:0009505 (plant-type cell wall)