Protein: NUDIX hydrolase, conserved (Q57Z14)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MYRKNVCVVIFNEDLNFLACQRIHEDKFQFVQGGVEEGDADIIRAAYREVHEEVGLFPEDLRLIGEIMPPSGDPHEFRYILHEGANLRHFGYVGQQQRLFLFYTPSSTIQRVRLVPPKGSVAKQEFSHVEWLPIDEIIERCPKEKQHIFVAVSKVAIPMAKAFLKTRSSI
InterPro domains: - IPR000086: NUDIX hydrolase domain (domain) [1-154]
- IPR022927: RNA pyrophosphohydrolase RppH (family) [1-156]
- IPR015797: NUDIX hydrolase-like domain superfamily (homologous_superfamily) [3-144]
Interaction partners: - 5'-3' exoribonuclease 2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0065008 (regulation of biological quality), GO:0044237 (cellular metabolic process), GO:0019222 (regulation of metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0009892 (negative regulation of metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0044248 (cellular catabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0034655 (nucleobase-containing compound catabolic process), GO:0009057 (macromolecule catabolic process), GO:0044270 (cellular nitrogen compound catabolic process), GO:0090304 (nucleic acid metabolic process), GO:0044265 (cellular macromolecule catabolic process), GO:0019439 (aromatic compound catabolic process), GO:1901361 (organic cyclic compound catabolic process), GO:0046700 (heterocycle catabolic process), GO:0010629 (negative regulation of gene expression), GO:0010468 (regulation of gene expression), GO:0016070 (RNA metabolic process), GO:0006402 (mRNA catabolic process), GO:0006401 (RNA catabolic process), GO:0016071 (mRNA metabolic process), GO:0000956 (nuclear-transcribed mRNA catabolic process), GO:0000288 (nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay), GO:0110154 (RNA decapping), GO:0000290 (deadenylation-dependent decapping of nuclear-transcribed mRNA), GO:0110156 (methylguanosine-cap decapping)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)