Protein: Nickel import ATP-binding protein NikD (EC 7.2.2.11) (P33593)
Organism: Escherichia coli (strain K12)
Function: Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_01711}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01711}.
Sequence: MPQQIELRNIALQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAATLGILPAGVRQTAGEILADGKPVSPCALRGIKIATIMQNPRSAFNPLHTMHTHARETCLALGKPADDATLTAAIEAVGLENAARVLKLYPFEMSGGMLQRMMIAMAVLCESPFIIADEPTTDLDVVAQARILDLLESIMQKQAPGMLLVTHDMGVVARLADDVAVMSDGKIVEQGDVETLFNAPKHTVTRSLVSAHLALYGMELAS
InterPro domains: - IPR017871: ABC transporter-like, conserved site (conserved_site) [141-155]
- IPR050388: ABC Transporter, Nickel and Peptide Import (family) [7-244]
- IPR014138: Nickel import ATP-binding protein NikD (family) [18-245]
- IPR003593: AAA+ ATPase domain (domain) [28-218]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [4-250]
- IPR003439: ABC transporter-like, ATP-binding domain (domain) [2-241]
Interaction partners: - Nickel-binding periplasmic protein
- Nickel import ATP-binding protein NikE
- Nickel transport system permease protein NikB
- Nickel transport system permease protein NikC
- Probable D,D-dipeptide transport system permease protein DdpC
- Glutathione transport system permease protein GsiD
- Dipeptide transport system permease protein DppC
- Oligopeptide transport system permease protein OppC
- Uncharacterized ABC transporter ATP-binding protein YdcT
- Arginine transport ATP-binding protein ArtP
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0005215 (transporter activity), GO:0140657 (ATP-dependent activity), GO:0016887 (ATP hydrolysis activity), GO:0016787 (hydrolase activity), GO:0042626 (ATPase-coupled transmembrane transporter activity), GO:0022857 (transmembrane transporter activity), GO:0005515 (protein binding), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0140359 (ABC-type transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0015399 (primary active transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0022853 (active monoatomic ion transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity), GO:0046873 (metal ion transmembrane transporter activity), GO:0046915 (transition metal ion transmembrane transporter activity), GO:0017111 (ribonucleoside triphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:0015695 (organic cation transport), GO:0015846 (polyamine transport), GO:0015847 (putrescine transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0098796 (membrane protein complex), GO:1990351 (transporter complex), GO:0098797 (plasma membrane protein complex), GO:1902495 (transmembrane transporter complex), GO:0005886 (plasma membrane), GO:0043190 (ATP-binding cassette (ABC) transporter complex), GO:0098533 (ATPase dependent transmembrane transport complex)