wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: RING-type E3 ubiquitin transferase (A0A8M1P379)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasmic vesicle membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein
Sequence: MNMPLHQISVIPRDVTSSRVCSSGKAKEKDKQNEKPLGHSASRSSNISKAGSPTSVNAPCSFPRSSVTPSNQDICSSNDLAQDVGSQRPLQATVVMLNSNGKSSASQGVTMTTLCLDSPAKPKNRTLFGTEWLSLLKPSVNLKPEAGSLKFSKSLNDVGQKMDSLCSGLHFIDRTCSDGELETEKEQLMQNGQIKALNVHGVPPPLFASQPPSFLNNYKYISNPGPEQCLAPSAPPHSDRRRSSNFLRLIFPFTRSSTAGSLQVSEMGSYASRLHIDKSSSAVLDVSESCCMEEIGDDEVFEEVPSRWKMKMEGVRAPLCSLEEDCDLDQCTSPLSEKNAPLSPYSLSGDCCRICHCEGDDESPLITPCHCTGSLRFVHQACLQQWIKSSDTRCCELCKYDFIMETKLKPLRKWEKLQMTASERRKIMCSVTFHVIAITCVVWSLYVLIDRTAEEIKQAGRIPGGLKLHPGLAYGGSESRILEWPFWTKLVVVAIGFTGGLVFMYVQCKVYIQLWRRLKAYNRVIYVQNRPETCKIKVFDKPSLLEPNLENKEALVPAQSDTNSSQYTETEDYSMEILHV
InterPro domains: - IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [343-413]
- IPR011016: Zinc finger, RING-CH-type (domain) [344-405]
- IPR001841: Zinc finger, RING-type (domain) [352-399]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0070647 (protein modification by small protein conjugation or removal), GO:0032446 (protein modification by small protein conjugation), GO:0016567 (protein ubiquitination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0005769 (early endosome), GO:0031982 (vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle)
Protein: Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 (X1WHV8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Mitochondrion. Nucleus
Sequence: MEMELSTDVEELSKTTESQDIDSDDLLELNQFDGLPFSSRYYKLLRERKCLPVWEAKCEFMDSLINSQIVIVTGTAKTGQSTQIPQWCAEFCLSAQYQNGMVVCTQIHHQTTVELALRVADEMDVNIGNEVGYSIPLQACCSQDTVLRYCTDDVLLREMMSDPLLEQCGVVVLDQAQERTVSTDLLLGLLKDVLLTRPELRLVILSAPHSSEKLLRHYGSVPQIKLEGPQPCEVLFGSGRGGVKDYLCSALRLALEIHQNENHGDIVAFLATEQEIECAHAILRREGANLALSHGELVPVSLCPRQGDSLSLTEESKSRRVFLTCSPSEDLFWALHTIRFVIDAGVQKRYVYNPRIRANSIVIRPISKSQAESRKQLAGPTGKCFCLYQEDTSLPAESVPHLLESDITSTVLFLKRMEIAGLSHCDLIDRPDPEGLMQALEELDYLAALDDDGNLSEIGIIMSEFPLEPQMAKTLLASCEFDCVCEVLTIAAMLTAPSCFIIPPVEMRQKALLCHQKFQHAEGDHFTLINIFNAYRYAKDGSYSKVEQWCDEHFLSLAALQTADAIRSELTEILKRLELPVSLPAFGSRSNSLNVRRALLAGFFMQVARDIDGSGNYFMLTHKHVAQIHPLSGYGLEVNKKNLPEWVLYHEHTLSENNCIRTVSQISAIEFIQMAPQYFFYNLPSSESKDLLQHTIDHGTAAPSKGKRKCQNSSSAATEEQTPERCTIQ
InterPro domains: - IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [61-227]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [3-554]
- IPR048333: Helicase associated domain (HA2), winged-helix domain (domain) [439-467]
- IPR007502: Helicase-associated domain (domain) [438-529]
- IPR011709: DEAD-box helicase, OB fold (domain) [595-678]
Interaction partners: - Something about silencing protein 10
- Nucleolar protein 58
- BMS1 ribosome biogenesis factor
- Tuftelin-interacting protein 11
- Nucleolar protein 56
- WD repeat domain 36
- Activator of basal transcription 1
- Pre-mRNA-splicing factor SYF1
- Pre-mRNA-processing-splicing factor 8
- Si:dkey-251i10.3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0008380 (RNA splicing), GO:0006397 (mRNA processing), GO:0016071 (mRNA metabolic process), GO:0000398 (mRNA splicing, via spliceosome), GO:0000375 (RNA splicing, via transesterification reactions), GO:0000377 (RNA splicing, via transesterification reactions with bulged adenosine as nucleophile)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Pentraxin family member (A3KPH5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted
Sequence: MLGFIFTLLILTPAAAEVGLGGKVLLFPTQSATSYVKLTPDKLLSLSAFTLCMRVATELQGGREVILFAYRTSEVDELNVWRENDGRLSMYIQSSSDAARFYLPPLSTFQTHLCVSWESATGLTAFWVDGRRSLYQIYKKDASVRPGGTVLLGQDPDSYVGSFDANQCFIGEITDVKLWDYVLSEIQIKALYSNQDPLVPAGNVFDWDTVKYDVVGNVTVANDNL
InterPro domains: - IPR001759: Pentraxin domain (domain) [17-225]
- IPR030476: Pentaxin, conserved site (conserved_site) [112-119]
- IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [19-221]
- IPR051005: Pentraxin domain-containing protein (family) [6-222]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:0097159 (organic cyclic compound binding), GO:0008289 (lipid binding), GO:0043178 (alcohol binding), GO:0005496 (steroid binding), GO:0032934 (sterol binding), GO:0015485 (cholesterol binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:0009617 (response to bacterium), GO:0043207 (response to external biotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009986 (cell surface)
Protein: RING finger protein 4 (A0A0R4IUS5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MSTTVTQRKRRTSTTCSRRGNSKRNRAQMSQTVMETIDVLENDRTNSEDVVDLTCEGSEPAVVDLTNNDSIVVVEDGVQRRVGPCTESYVLSSDEEEESSLRLSPGLLSSLRDSSRARSTPGAISCPVCMDVYSEIMDSGRLMVSTKCGHLFCSQCIRDSLSRAHSCPTCRKKLTHKQYHPIYI
InterPro domains: - IPR017907: Zinc finger, RING-type, conserved site (conserved_site) [148-157]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [122-184]
- IPR047134: E3 ubiquitin-protein ligase RNF4 (family) [12-184]
- IPR001841: Zinc finger, RING-type (domain) [126-171]
Interaction partners: - Small ubiquitin-related modifier
- Small ubiquitin-related modifier
- Small ubiquitin-related modifier 1
- Small ubiquitin-related modifier 2
- KxDL motif-containing protein 1
- Ubiquitin-conjugating enzyme E2N-like
- Ube2n protein
- Small ubiquitin-related modifier 3-like
- Ubiquitin-ribosomal protein eL40 fusion protein
- Ubiquitin-ribosomal protein eS31 fusion protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0030154 (cell differentiation), GO:0048468 (cell development), GO:0030097 (hemopoiesis), GO:0030099 (myeloid cell differentiation), GO:0002521 (leukocyte differentiation), GO:0002573 (myeloid leukocyte differentiation), GO:0030851 (granulocyte differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Vezatin (A0A0R4IYV3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell junction, adherens junction. Cell membrane; Multi-pass membrane protein. Nucleus
Sequence: MTEDFDEEVVFENSPLFQYLQDLGHTDFEACTPVSQEEEPGAGGEEAPFPQDILQSRTKSGVWRLVDALRGLNPLRRDSATHWQEQQLDSAFRQSSLRCLLSQDVLLQEDVELIELLDPSVLSLGSADTVCPSAAVPAPRCLSTFSIWDVSVLVGLLSVLLGLCFSSSDLEPSLWLCVYLLCVLSVCRGLCLWRKTDLQRRVQSLAVQLEDLVNNSRSLTSLSRKSLRLIQETEVISRGFTLVSGACPFNRAGQLRSQQLIGLRKAAYQSLRCAFRASRLATCVMLKSFPLNSEIDNVTNYVSTVPIRELGLGLGVEHLSDEQAQELTNDYSLPALKMLFQLWVGQSSEFFRRLALLLSPGREEQDSRPCPVSYSSIPLITDALHRSLSSCLADLQRSYDFHRYFETQHQPMASGRHRRAQQKCRELNSLHTSVRSLQLHLKTLLNEVIILEDDLEKLMVARESDEVTCAGYQELKERLQLLQPHMQASSCCWDDTIAQVERMLRRVSSCPEGSDQPEETTVPDPPPSAPITHIQDRDPVPEEQELEAYVSDSDSDTEWRGGSDMLSPCELERQRREREESRRVLLELKSVLGIRTSDGERDKRKLLLFSDQAALAPFAKDSSETGTNSLDTEISLDSTTATINHVSPLDEQNKNTPQTETLNALEHENQAVTEFTCGDSDSTAAAKDAIEETPQETQLFQSDGLIDAGHDGIHPLSARVPTVSVMDRLTEMHGTEAISFSSALAAQVAARSHTFTNMQECTYEDSDEEEEATSQQTRESEDD
InterPro domains: - IPR026859: Myosin-binding domain (domain) [153-442]
- IPR026858: Vezatin (family) [1-773]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007155 (cell adhesion), GO:0007275 (multicellular organism development), GO:0098609 (cell-cell adhesion), GO:0009790 (embryo development), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: PHD finger protein 6 (Q803W6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MSGQRKGASARLRKCAFCRTNRDKECGQLLVAESHRVAAHHKCMLFSSALVTSHSDSENIGGFSIEDVKKEIKRGNKLMCTSCHRPGATIGCDVKTCRRTYHYYCALWDKAQTKENPSQGIYLVYCRKHRDASQDGSDDEQGVAANDSDSSPPRSRGRGRFEKSRIRGVSRGQSDDTRSTSSQGNDDTESSSHRDRSPLRGSPGDSGLRCGFCHAGEEENETRGVLHSDNAKKVAAHCKCMLFSSGTVQLTTSSRAEFGNFDIKTVIQEIKRGKRMKCTLCAQLGATIGCEIKACVKTYHYHCGLQDKAKYIENMARGIYKLYCKNHSGNEERDEEDEERESRSREKAAIDNRADPPSQVNGN
InterPro domains: - IPR011011: Zinc finger, FYVE/PHD-type (homologous_superfamily) [75-108]
- IPR051188: PHD-type Zinc Finger Domain-Containing Protein (family) [6-197]
- IPR001965: Zinc finger, PHD-type (domain) [79-328]
- IPR034732: Extended PHD (ePHD) domain (domain) [12-328]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [9-330]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:1901363 (heterocyclic compound binding), GO:0097159 (organic cyclic compound binding), GO:0003676 (nucleic acid binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003677 (DNA binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding), GO:0000987 (cis-regulatory region sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0071684 (organism emergence from protective structure), GO:0007275 (multicellular organism development), GO:0001824 (blastocyst development), GO:0009790 (embryo development), GO:0035188 (hatching), GO:0009792 (embryo development ending in birth or egg hatching), GO:0001835 (blastocyst hatching), GO:0043009 (chordate embryonic development), GO:0001701 (in utero embryonic development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Exportin-1 (A0A8M9PPG9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
Sequence: MPAIMTMLADHAARQLLDFNQKLDINLLDNVVNCLYHGVGPQQRMAQEVLTHLKEHPDAWTRVDTILEFSQNMNTKYYALQILETVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDAANVEKEKVYIGKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNNMIILKLLSEEVFDFSSGQMTQVKAKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGYIFETKLISTLVYKFLNVPMFRNVTLKCLTEIAGVSVSQYEEQFVNLFTLTMMQLKQMLPLNTNIRLAYANGKDDEQNFIQNLSLFLCTFLKEHGQLIEKRLNLRETLMEALHYMLLVSEVEETEIFKICLEYWNHLAAELYRESPFSTSTSPLLSGSQHFDVPPRRQLYLPVLSKVRLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYADTERIMTEKLHNQVNGTEWSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKRGKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIAQKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQAVQEHLIEKYMLLPNQVWDSIIQQATKNVDILKDPETVKQLGSILKTNVRACKAVGHPFVIQLGRIYLDMLNVYKCLSENISAAIQTNGEMVTKQPLIRSMRTVKRETLKLISGWVSRSNDPQMVGENFVPPLLDAVLIDYQRNVPAAREPEVLSTMATIVNKLGGHITGEIPQIFDAVFECTLNMINKDFEEYPEHRTHFFYLLQAVNSHCFPAFLAIPPAQFKLVLDSIIWAFKHTMRNVADTGLQILYTLLQNVAQEEAAAQSFYQTYFCDILQHIFSVVTDTSHTAGLTMHASILAYMFNLVEEGKISTTLNPSNPVNNQVFIQEYVANLLKSAFPHLQDAQVKVFVTGLFSLNQDIAAFKEHLRDFLVQIKEFAGEDTSDLFLEEREASLRQAQEEKHKLQMSVPGILNPHEIPEEMCD
InterPro domains: - IPR041123: Chromosome region maintenance repeat (repeat) [345-381]
- IPR045065: Exportin-1/5 (family) [20-1066]
- IPR016024: Armadillo-type fold (homologous_superfamily) [28-1033]
- IPR011989: Armadillo-like helical (homologous_superfamily) [1-1055]
- IPR014877: Exportin-1, C-terminal (domain) [709-1027]
- IPR013598: Exportin-1/Importin-beta-like (domain) [124-268]
- IPR040485: Exportin-1, repeat 3 (repeat) [485-535]
- IPR001494: Importin-beta, N-terminal domain (domain) [46-112]
- IPR041235: Exportin-1, repeat 2 (repeat) [405-472]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Heterogeneous nuclear ribonucleoprotein U-like 1 (Q6NUT5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
Sequence: MSLDVKKLKVNELKEELQKRGLDSRGLKADLVERLLAALEDEKQPTCDEEVETGVAEAGNDEQSDQEQMAGEKESSEMGTDFPEVPNDESKIKSVDEQPATVETVSKEEHEVAPVKLKSEDDIKTEEQEQRPEASSEREALESQQTEECKTEPDRHSHHGHKRRYDEAHGNSHYDHREDKRSRSPQPSAEEDDEDFDDTLVAIDTYNSDLHFKVSPDHCSGYPLTIEGFAYLWSGARATYGVNKGRVCYELKVKEYISVKHLPSSEPDPHVVRVGWSLDSCSTQLGEEAFSYGYGGTGKKSTNYKFGDYGEKFGEGDIIGCYIDFDSHEQVEMAFSKNGKWLDVAFRVSKEELAGQALFPHVLVKNCAVEFNFGQREEPYFPLPDGYSFIGDVSLENRVRGTVGPSSKSDCQVLMMVGLPACGKTTWAAKHAEMNPDKRFNILGTNAIMEKMKVMGLRRQRNYAGRWDILIQQATQCLNRLLQIASHKKRNYILDQTNVYGSAQRRKMRPFEGFHRKAVVICPRDEDLKERRCKQAEDGKDVPDQAVLEMKANFVLPEAGDFLDEVMFIELQRDEARDLIKRYNEEGRKAGPPPEKRFNSWGDRRRENNNNQRYDSHGGSRGGHQSRGGSGGGYSGGGYNRDGYSQNRWGGNYRDSRDGYSSSSSHQTGGNYNNSRYGSYNKEGYGQGYNQGYNQGNQSSYGQGNYNQGYNYGNYNQYPGYGQGYQDNQGSGQSYNQQNYNQQYQQYAQQWQEYYQNQSQWNQYYGQYGNYSGQQGSQSSYGSQ
InterPro domains: - IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [199-380]
- IPR036361: SAP domain superfamily (homologous_superfamily) [2-46]
- IPR001870: B30.2/SPRY domain (domain) [181-378]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [407-585]
- IPR003877: SPRY domain (domain) [244-377]
- IPR043136: B30.2/SPRY domain superfamily (homologous_superfamily) [199-410]
- IPR003034: SAP domain (domain) [4-40]
- IPR035778: Heterogeneous nuclear ribonucleoprotein U, SPRY domain (domain) [201-378]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:0009410 (response to xenobiotic stimulus), GO:0070887 (cellular response to chemical stimulus), GO:0071466 (cellular response to xenobiotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Carbonic anhydrase Xb (A0A8M2BBM0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Does not have a catalytic activity
Sequence: MPHVWEFVLILNINVIFVEAQPVSSKLHDGWWAYKDVVQGSFIPVPSFWGLVNTAWNLCAIGKRQSPVNIETSRMIFDPFLNPLRLNAGQRKVSGTMYNTGRHVSLRPDKSHLVNISGGPLSYSYRLEEIRLHFGSEDNRGSEHLLNGQAFPGEVQLIHYNQDLYLNYSDAVRSPNGIAVVSIFMKISEPTNVFLNRMLNRETVTRITYKHDAYLLMGLNIEELYPETSRFITYEGSITIPPCLETATWILMNKPIYISQIEMQSLRLLSQNQPSQIFLSMGDNMRPTQTLHQRCIRTNINFSQRRDCPNNRMLRPQYRVNEWLLK
InterPro domains: - IPR023561: Carbonic anhydrase, alpha-class (family) [30-294]
- IPR036398: Alpha carbonic anhydrase domain superfamily (homologous_superfamily) [26-309]
- IPR001148: Alpha carbonic anhydrase domain (domain) [30-300]
- IPR041878: Carbonic anhydrase-related protein X/XI (family) [45-301]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016835 (carbon-oxygen lyase activity), GO:0016836 (hydro-lyase activity), GO:0004089 (carbonate dehydratase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0007610 (behavior), GO:0007626 (locomotory behavior), GO:0036269 (swimming behavior)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Vezatin (A8WFS3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell junction, adherens junction. Cell membrane; Multi-pass membrane protein. Nucleus
Sequence: MTCSCLFTTSHCKNSPLFQYLQDLGHTDFEACTPVSQEEEPGAGREEAPFPQDILQSRTTCVWRLVDALRGLNPLRRDSATHWQEQQLDSAFRQSSLRCLLSQDVLLQEDVELIELLDPSVLSLGSADTVCPSAAVPAPRCLSTFSIWDVSVLVGLLSVLLGLCFSSSDLEPSLWLCVYLLCVLSVCRGLCLWRKTDLQRRVQSLAVQLEDLVNNSRSLTSLSRKSLRLIQETEVISRGFTLVSGACPFNRAGQLRSQQLIGLRKAAYQSLRCAFRASRLATCVMLKSFPLNSEIDNVTNYVSTVPIRELGLGLGVEHLSDEQAQELTNDYSLPALKMLFQLWVGQSSEFFRRLALLLSPGREEQDSRPCPVSYSSIPLITDALHRSLSSCLADLQRSYDFHRYFETQHQPMASGRHRRAQQKCRELNSLHTSVRSLQLHLKTLLNEVIILEDDLEKLMVARESDEVTCAGYQELKERLQLLQPHMQASSCCWDDTIAQVERMLRRVSSCPEGSDQPEETTVPDPPPSAPITHIQDRDPVPEEQELEAYVSDSDSDTEWRGGSDMLSPCELERQRREREESRRVLLELKSVLGIRTSDGERDKRKLLLFSDQAALAPFAKDSSETGTNSLDTEISLDSTTATINHVSPLDEQNKNTPQTETLNALEDENQAVTEFTCGDSDSTAAAKDAIEETPQETQLFQSDGLIDAGHDGIHPLSARVPTVSVMDRLTEMHGTEAISFSSALAAQVAARSHTFTNMQECTYEDSDEEEEATSQQTRESEDD
InterPro domains: - IPR026859: Myosin-binding domain (domain) [153-442]
- IPR026858: Vezatin (family) [13-773]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007155 (cell adhesion), GO:0007275 (multicellular organism development), GO:0098609 (cell-cell adhesion), GO:0009790 (embryo development), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Proenkephalin-B (A0A8M3B6F1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opioid activity, it is 700 times more potent than Leu-enkephalin
Subcellular location: Secreted
Sequence: MMEWYVLVLMLSFPTLSQADCSAQCLRCAQQISDLDSAVNRLTCTLECEGAVPPTGTLDRCEKALQGLSDDLAELNTGADGETNALNTDEDLQEKTSNLVKRYGGFIKRIDKNKNKFFSSPWKENAILKGLFAKKYGESLSKLGERDLPSITEDDEGEDMGAENETGVYDNEVPLNEVKRYGGFLRKFGPKRSYFVDDTNPQVLQKRYGGFMRRIRPKLRWDNQKRYGGFLRRHFKISVRSDEEPSSYEDYAL
InterPro domains: - IPR006024: Opioid neuropeptide precursor (family) [2-250]
- IPR000750: Proenkephalin B (family) [101-252]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0001664 (G protein-coupled receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0043010 (camera-type eye development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)