Protein: Uncharacterized protein F31E3.4 (P53015)
Organism: Caenorhabditis elegans
Function: Not known
Sequence: MASATTNQGNEWRFVAPININTTTENTVSCVKFDPHEDLFWIGSSTGKVTSLLPTNHFTRYSAFVVSNISGVHSLEPTESLIFTLSDTMLRATTRQGIPVAKFTSPSMTKMAASCHMPGTSTFIMGGFQEKLIHYDFVKEKEIRTTELKASENAIIIRYNGTNTFTADTRGNVFVKNSKNCETIHTLDCHQDQVLDFDVQGNKLITCGVSMNRLKNMDQFIKVYDLRMYKALSPIGMPYLPQFARFMPSYCERVCVTYQTMYNQPGQTATWSNHPAGVKMFDLNSNGNSAEFPIETSLISAFDFSSNKNFIAVGNHCGIVNVFADRDQPQVNENSKETVFAAPPVQPPLSFAIDDTTQTFGSIPLGFSQEPLVSDWPTELTQIVYRRRKPPTEQTNVKSIHYLSQIKNPRINSKLKRHNIVPYFFEQEELIEASNDHGSKEEAPQEMKRIKVSKLYKKRPLIVNQVPARRGNSQDETQETYTWNIIRHVTMQSTHGMNLVANTLVQVAYSLSPIRSIVLRHICTEDSCITCELHFLFTAFSSKIGDNSGMLTNNLAWALARNGVSLKAGGVLSATQQIIKTVIDDVARTDASGSICSKFDRHLRCIRCRGLQQQESVTDHLLKLNYAPVYQASLCQLIEKSLHIGDDSGEIECEDCKQMSRMECKRKVRELSPVLLIDTNASSNGFVEFWRRQLSLFERKPGGNRSSALGTVPESPSEKKNCRFGTDCRNKKTCKFVHGLVDWPAEQTKLLEDVDLPEWAHYIPSRIAAQLCEGIVRLSDVSDLPDYDEPSAVIYELDAMIHAVGNGENDVNWTHPVTLLRESPVISSSWTLINEQLVSRLHDHEARHIDGRWKLPALLAYKKKNFDVKTSEDIISNDLFLAEENLASNGMTSLAVQSLEELPKEKELVGLDAEFIKIKTDLLEFDGKTVQMRAVGRASCVDSTGERIIFDDHVKLTDDVEVVDYLTKFSGIVKADLCPTTSEKYLTTHKRLLLRMHVLIQRGVTFVGHALHNDFTVLNVHVAESQIIDTVTLMRLGTQRMLSLQFLVKEILGETIQMEAHDSVVDARYALKLYRKYLEIKEQGLLGSEMRRIYTILPCPSPNQTSSPLVVSTTRKTPEDTNPADAAPKSV
InterPro domains: - IPR050785: PAN2-PAN3 complex catalytic subunit (family) [11-577]
- IPR012337: Ribonuclease H-like superfamily (homologous_superfamily) [906-1078]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [6-333]
- IPR028881: PAN2, UCH domain (domain) [494-838]
- IPR036397: Ribonuclease H superfamily (homologous_superfamily) [904-1094]
- IPR013520: Ribonuclease H-like domain (domain) [893-1083]
- IPR048841: PAN2-PAN3 deadenylation complex catalytic subunit PAN2, N-terminal (domain) [27-323]
- IPR028889: Ubiquitin specific protease UPS, catalytic domain (domain) [489-864]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [24-323]
Interaction partners: - PAN2-PAN3 deadenylation complex subunit PAN3
- Target of EGR1 protein 1
- CCR4-NOT transcription complex subunit 7
- poly
- Endonuclease/exonuclease/phosphatase domain-containing protein
- CCR4-NOT transcription complex subunit let-711
- 3'-5' exoribonuclease parn-1
- Polyadenylate-binding protein
- Polyadenylate-binding protein
- Proliferating cell nuclear antigen
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0019222 (regulation of metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0009056 (catabolic process), GO:0009892 (negative regulation of metabolic process), GO:0065008 (regulation of biological quality), GO:0044237 (cellular metabolic process), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0048522 (positive regulation of cellular process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0048523 (negative regulation of cellular process), GO:0048609 (multicellular organismal reproductive process), GO:0044238 (primary metabolic process), GO:0007276 (gamete generation), GO:0007281 (germ cell development), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0043487 (regulation of RNA stability), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0046483 (heterocycle metabolic process), GO:0044248 (cellular catabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0043170 (macromolecule metabolic process), GO:0009894 (regulation of catabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0033554 (cellular response to stress), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0080090 (regulation of primary metabolic process), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0009896 (positive regulation of catabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0034655 (nucleobase-containing compound catabolic process), GO:0044270 (cellular nitrogen compound catabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0006974 (cellular response to DNA damage stimulus), GO:0051246 (regulation of protein metabolic process), GO:0043488 (regulation of mRNA stability), GO:0019439 (aromatic compound catabolic process), GO:0051248 (negative regulation of protein metabolic process), GO:0048477 (oogenesis), GO:0046700 (heterocycle catabolic process), GO:0050779 (RNA destabilization), GO:0010468 (regulation of gene expression), GO:0009057 (macromolecule catabolic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0034248 (regulation of amide metabolic process), GO:0007292 (female gamete generation), GO:0090304 (nucleic acid metabolic process), GO:0044265 (cellular macromolecule catabolic process), GO:1901361 (organic cyclic compound catabolic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0031331 (positive regulation of cellular catabolic process), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0051252 (regulation of RNA metabolic process), GO:0031329 (regulation of cellular catabolic process), GO:0010629 (negative regulation of gene expression), GO:0034249 (negative regulation of amide metabolic process), GO:0017148 (negative regulation of translation), GO:0016070 (RNA metabolic process), GO:0061013 (regulation of mRNA catabolic process), GO:0061014 (positive regulation of mRNA catabolic process), GO:0006402 (mRNA catabolic process), GO:0006401 (RNA catabolic process), GO:2000112 (regulation of cellular macromolecule biosynthetic process), GO:0006417 (regulation of translation), GO:1903311 (regulation of mRNA metabolic process), GO:0061157 (mRNA destabilization), GO:2000113 (negative regulation of cellular macromolecule biosynthetic process), GO:1903313 (positive regulation of mRNA metabolic process), GO:0010608 (post-transcriptional regulation of gene expression), GO:0000956 (nuclear-transcribed mRNA catabolic process), GO:0016071 (mRNA metabolic process), GO:0000288 (nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay), GO:0000289 (nuclear-transcribed mRNA poly(A) tail shortening)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0043229 (intracellular organelle), GO:0035770 (ribonucleoprotein granule), GO:0036464 (cytoplasmic ribonucleoprotein granule), GO:0045495 (pole plasm), GO:0043228 (non-membrane-bounded organelle), GO:0043186 (P granule), GO:0060293 (germ plasm), GO:0043232 (intracellular non-membrane-bounded organelle)