Protein: Microtubule-associated serine/threonine-protein kinase 3 (Q3U214)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm
Sequence: MKSRREKLLIPALTLDLSPSSQSPCLLSPGSPCSPCSPSLGLQPWSCRSGNRKSLVVGTPSPTLSRPLSPLSVPTAGNSPLDSPRNFSAAAAISFPFARRADGRRWSLASLPSSGYGTNTPSSTVSSSSSSRERLHQLPFQPTADELRFLSKHFRSSESVVDEDGGRSPRLRPRSRSLSPGRTSGTFDNEIVMMNHVYRERFPKATAQMEGRLQDFLAAFAPGDRLALADGVLGFIHHQIVELARDCLAKSGEALVTSRYFLEMQDKLERLLQDAHERSDSAEVGFIVQLVRKLLIIISRPARLLECLEFDPEEFYHLLEAAEGQAREDQGVKTDLPRYIIRQLGLAKDPLEEIQPLNDLDESQPPAPGSPESRGLGGPSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFVDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVILYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEGDEALPLDAQDLITRLLRQSPMDRLGTGGTHEVKQHPFFLALDWAGLLRHKAEFVPQLEAEDDTSYFDTRSERYRHLGSEDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFLAVQPTPTFAERSFSEDREDGWGQSLGDRGRRLSADLRLRSWTPASSCQPSSCQTDRGPSPSLLSTISLDVMPKFAFSSEDEGASSGPADPQKPVFILGEPDPPPPTTPVTPKPCNLSADTAVLSHARLRSNSTGARHSTPRPLDAGRGRRLGGSRDPGPEKPRASPGGSGGRVPKSASVSALSLIITADDGSGGPLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIHSSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEEGSPAQEAGLRAGDLITHINGESVLGLVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDRRKSLFKRISKPSSVLHTSRSFSSGLQHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDAPTDTASPPNVSPSSSSPASPATGHTRPSSLHGLAAKLGPPRHKSGRRKSTSSIPPSPLACPPVPTPPPRSPSPLPGHIPIPARSPRLRRGQSADKLGLGTSERLDGDGGRRARGAEAELVVMRRLHLSERRDSFKKQEAVQEVSFDEEPGPPRGVPKIAVQGAEATPGTPGHARKD
InterPro domains: - IPR001478: PDZ domain (domain) [966-1054]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [508-520]
- IPR037711: Microtubule-associated serine/threonine-protein kinase, catalytic domain (domain) [388-667]
- IPR050236: Serine/threonine-protein kinases, AGC (family) [144-713]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [387-741]
- IPR041489: PDZ domain 6 (domain) [1001-1040]
- IPR023142: Microtubule-associated serine/threonine-protein kinase, pre-PK domain superfamily (homologous_superfamily) [203-303]
- IPR000719: Protein kinase domain (domain) [389-662]
- IPR015022: Microtubule-associated serine/threonine-protein kinase, pre-PK domain (domain) [80-353]
- IPR000961: AGC-kinase, C-terminal (domain) [663-734]
- IPR036034: PDZ superfamily (homologous_superfamily) [962-1060]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0015631 (tubulin binding), GO:0008017 (microtubule binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0016043 (cellular component organization), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development), GO:0006996 (organelle organization), GO:0007010 (cytoskeleton organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0036477 (somatodendritic compartment), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0044297 (cell body), GO:0043025 (neuronal cell body), GO:0120025 (plasma membrane bounded cell projection), GO:0043005 (neuron projection)