wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Prestalk A differentiation protein A (Q54LW0)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Involved in development and cell differentiation.
Sequence: MQTNITSTKMSILVTGGTGVVGRQVVKSLELREKNINIRVGGRDQDKCNQLGFGKNSTFTRFDFMDPTTWDKSLEGVDRVFLIALPMDPTPEKSLGPFIEKCKERKLKKIVVLSVIDAERVPLVKIEQMVQGSGLTFVILRPPFFSENFSEGFMKHDIDQGTIRVPVGEHSVNWISTHDIGECASIVLMDSKFDGRTIEITGPKPINFKELSEVVSKNVGKQIRFEDIKPQEYKKCLMDRGISEPSANYLNELFTSAREDKLSKCTKGVNEITGHDPRSFEQFAKETFSNTSGSCTSKPVI
InterPro domains: - IPR051604: Ergot Alkaloid Biosynthesis Oxidoreductase (family) [10-292]
- IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [9-254]
- IPR016040: NAD(P)-binding domain (domain) [16-148]
Interaction partners: - Cytochrome b-c1 complex subunit Rieske, mitochondrial
- NADH-ubiquinone oxidoreductase 23 kDa subunit
- NADH dehydrogenase flavoprotein 1, mitochondrial
- NADH-ubiquinone oxidoreductase subunit 9
- NADH-ubiquinone oxidoreductase 49 kDa subunit
- NADH dehydrogenase 1 alpha subcomplex subunit 12
- Cytochrome c1, heme protein, mitochondrial
- NADH dehydrogenase flavoprotein 2, mitochondrial
- NADH dehydrogenase iron-sulfur protein 4
- NADH-ubiquinone oxidoreductase 75 kDa subunit
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:1901700 (response to oxygen-containing compound), GO:0014070 (response to organic cyclic compound), GO:1901654 (response to ketone), GO:0033574 (response to testosterone)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0030139 (endocytic vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle), GO:0045335 (phagocytic vesicle)
Protein: 4,5-DOPA dioxygenase extradiol (MjDOD) (EC 1.13.11.29) (DOPA 4,5-dioxygenase) (B6F0W8)
Organism: Mirabilis jalapa (Garden four-o'clock)
Function: Opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid. Produces mainly (S)-betalamic acid. Required for the coloration of flowers.
Subcellular location: Cytoplasm {ECO:0000305}.
Sequence: MKGTYYINHGDPLMYLKKHIKLRQFLEGWQENVVIEKPKSILIISAHWDTNVPTVNFVEHCDTIHDFDDYPDPLYQIQYRAPGAPNLAKKVEELLKESGMECEIDTKRGLDHAAWFPLMFMYPEANIPICELSVQPSKDGIHHYNVGKALSPLLQQGVLIIGSGGTVHPSDDTPHCPNGVAPWAIEFDNWLEDALLSGRYEDVNNFKKLAPNWEISHPGQEHLYPLHVALGAAGKNPKTQLIHRSWAANGVFGYSTYNFTPTTQKTD
InterPro domains: - IPR004183: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B (domain) [5-256]
- IPR014436: Extradiol aromatic ring-opening dioxygenase, DODA-type (family) [1-261]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0051213 (dioxygenase activity), GO:0016701 (oxidoreductase activity, acting on single donors with incorporation of molecular oxygen), GO:0016702 (oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006725 (cellular aromatic compound metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Probable acetyl-CoA acetyltransferase (EC 2.3.1.9) (Acetoacetyl-CoA thiolase) (Q86AD9)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Not known
Sequence: MISNLSKVLNSNVKRMYTTAKNLESVVIVSAVRTPIGSIGGSLSTIPGTKLSSITIEEAVKRAGIKPSDVDEAIIGNVISANLGQAPARQCALGAGLEQKTITTTINKVCSSGMKAIVFGAQSIALGHSKTVVAGGFESMSQVPYYADKMRFGAKYGNQTFIDGLVRDGLADAYNGSAMGVCGDDCADKYKITREQQDKFAVDSYLRALEAQKNGFFNDEIVQVPIVGRGGKVTYVVEDEEPKKVLFDKIPNLKPAFTPNGTVTPANASKLNDGASSVILMSESHAKELGLKPLARIIGYADAEQAPIEFPTAPALAIPKALKNAGINMSQVDLFEINEAFAVVGLANAKILDIDHNKLNVNGGAVALGHPIGSSGCRIVVTLTHLLQNKNLKYGVAAICNGGGGSTALVLEKL
InterPro domains: - IPR020616: Thiolase, N-terminal (domain) [26-284]
- IPR002155: Thiolase (family) [20-414]
- IPR020613: Thiolase, conserved site (conserved_site) [360-376]
- IPR020617: Thiolase, C-terminal (domain) [291-413]
- IPR016039: Thiolase-like (homologous_superfamily) [16-414]
- IPR020615: Thiolase, acyl-enzyme intermediate active site (active_site) [106-124]
Interaction partners: - 3-hydroxybutyryl-CoA dehydrogenase
- Hydroxymethylglutaryl-CoA synthase B
- Hydroxymethylglutaryl-CoA synthase A
- Probable succinyl-CoA:3-ketoacid coenzyme A transferase, mitochondrial
- malate synthase
- Peroxisomal acyl-coenzyme A oxidase 1
- Acetyl-CoA carboxylase
- Probable short/branched chain specific acyl-CoA dehydrogenase
- Mevalonate kinase
- Citrate synthase, mitochondrial
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016408 (C-acyltransferase activity), GO:0016407 (acetyltransferase activity), GO:0003988 (acetyl-CoA C-acyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0051703 (biological process involved in intraspecies interaction between organisms), GO:0099120 (socially cooperative development), GO:0048856 (anatomical structure development), GO:0030587 (sorocarp development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0030139 (endocytic vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle), GO:0045335 (phagocytic vesicle)
Protein: Transducin/WD40 repeat-like superfamily protein (F4HUT3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MWEAIKDRETGRIRSNSFANRFKSRRILSLQLSNRKDFVSPHRGSVNSLQVDLTEGRYLLSGAADGSAAVFDVQRATDYEASGLIAKHKCIFTVDKQHENGHKYAISSAIWYPIDTGLFITGSFDHYLKVWDTNTAQAVVDFKMPGKVYRTAMSSMAMSHTLIAAGTEDVQVRLCDIASGAFSHTLSGHRDGVMSVEWSTSSEWVLYTGGCDGAIRFWDIRRAGCFRVLDQSQTQLGFRPPILKRTAVGSKLSSVAKSSLGGQNRLKTLQSKQTGSQSVKGSSSAKASVEKSRQKRIHPGMLSTLDRATAHYGAVTGLKATNDGMYLLSAGSDSRIRLWDIESGRNTLVNFETGRIQTNKGIQLDTSDDPALVFVPCMKTVKVAFGMWSGRTTLMLRGHYESVNTCCFNSNDQELYTSGSDRQILVWSPGGTVEDEMVQDEVAEDKDNWSD
InterPro domains: - IPR001680: WD40 repeat (repeat) [33-428]
- IPR019775: WD40 repeat, conserved site (conserved_site) [206-341]
- IPR020472: PAC1/LIS1-like, WD-40 repeat (repeat) [119-341]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [1-437]
- IPR042238: DNA excision repair protein Rad28/ERCC8/Ckn1/ATCSA-1 (family) [1-451]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [39-429]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0044237 (cellular metabolic process), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0009314 (response to radiation), GO:0033554 (cellular response to stress), GO:0006259 (DNA metabolic process), GO:0009416 (response to light stimulus), GO:0090304 (nucleic acid metabolic process), GO:0006974 (cellular response to DNA damage stimulus), GO:0006281 (DNA repair), GO:0009411 (response to UV), GO:0010224 (response to UV-B)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Carboxyl-terminal protease (EC 3.4.21.-) (Q729L4)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Function: Not known
Sequence: MRVTLWVVSLGLCAAVAFSGGAVFATTEESKYDALKRFSQVLDIVERYYVRDVPRKDLMNGAVKGMLQGLDPHSTFLSPEEFKEMQETTSGEFFGIGIEISSENGQLTVVSPIEDTPAFKAGLKAGDLILAVDGQPTQEMSTQEAVSRIRGPKGSEVELLILHREAKAPSTVKIVRDAIPLVSVKSKQLEQGYVWVRLTRFSERTTSDLLEALREANKRGPVKGVVLDLRNNPGGLLDQAVSVSDVFLRDGGIVSIRGRGDDTGREYNAKAQSTDVTAPMVVLINAGSASASEIVAGALRDQKRALLVGERSFGKGSVQNVIPLSDGAGLKLTVALYYTPNGRSIQAEGIDPDIEIPFEAPREDDAKPMQRFNMLREKDLSRHLENGAGGKQGKNDQSDEVRDLLERDNQLRMALQFVKRLPALKEIR
InterPro domains: - IPR036034: PDZ superfamily (homologous_superfamily) [82-181]
- IPR055210: Activating protease CtpA/B, N-terminal domain (domain) [28-78]
- IPR004447: C-terminal-processing peptidase S41A (family) [31-359]
- IPR029045: ClpP/crotonase-like domain superfamily (homologous_superfamily) [32-361]
- IPR005151: Tail specific protease (domain) [167-357]
- IPR041489: PDZ domain 6 (domain) [109-161]
- IPR001478: PDZ domain (domain) [82-165]
Interaction partners: - Peptidase, M23/M37 family
- Pyruvate:ferredoxin oxidoreductase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0030030 (cell projection organization), GO:0022607 (cellular component assembly), GO:0030031 (cell projection assembly), GO:0043711 (pilus organization), GO:0009297 (pilus assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0031975 (envelope), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030312 (external encapsulating structure), GO:0009279 (cell outer membrane), GO:0019867 (outer membrane), GO:0030313 (cell envelope)
Protein: Probable glutathione S-transferase (EC 2.5.1.18) (G2-4) (Heat shock protein 26A) (P32110)
Organism: Glycine max (Soybean) (Glycine hispida)
Function: May play a role in the cellular response to stress.
Sequence: MAATQEDVKLLGIVGSPFVCRVQIALKLKGVEYKFLEENLGNKSDLLLKYNPVHKKVPVFVHNEQPIAESLVIVEYIDETWKNNPILPSDPYQRALARFWSKFIDDKIVGAVSKSVFTVDEKEREKNVEETYEALQFLENELKDKKFFGGEEFGLVDIAAVFIAFWIPIFQEIAGLQLFTSEKFPILYKWSQEFLNHPFVHEVLPPRDPLFAYFKARYESLSASK
InterPro domains: - IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [7-108]
- IPR045074: Glutathione S-transferases Tau, C-terminal alpha-helical domain, plant (domain) [91-217]
- IPR036282: Glutathione S-transferase, C-terminal domain superfamily (homologous_superfamily) [79-219]
- IPR045073: Glutathione S-transferase Omega/Tau-like (family) [5-223]
- IPR004046: Glutathione S-transferase, C-terminal (domain) [100-198]
- IPR010987: Glutathione S-transferase, C-terminal-like (domain) [90-214]
- IPR004045: Glutathione S-transferase, N-terminal (domain) [6-85]
Interaction partners: - Peroxiredoxin
- DHAR class glutathione S-transferase
- DHAR class glutathione S-transferase
- DHAR class glutathione S-transferase
- DHAR class glutathione S-transferase
- Glutathione peroxidase
- Glutathione peroxidase
- Glutathione peroxidase
- Glutathione peroxidase
- Glutathione peroxidase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups), GO:0046983 (protein dimerization activity), GO:0004364 (glutathione transferase activity), GO:0042803 (protein homodimerization activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0098754 (detoxification), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009407 (toxin catabolic process), GO:0009056 (catabolic process), GO:0044237 (cellular metabolic process), GO:0019748 (secondary metabolic process), GO:0042221 (response to chemical), GO:0044248 (cellular catabolic process), GO:0009404 (toxin metabolic process), GO:0009636 (response to toxic substance)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0042579 (microbody), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005777 (peroxisome)
Protein: Uncharacterized protein (Q387Z1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MAGGSTSPAVRAQQMMKTADLVNKFVISTAQFLNRFAAYCESKLLETNRSLQRLETLTLLLEAKIASVDDELKETQPQTVEGQTTVKALGDNVARLMIPDRQVPPPMPGLSPEGGQRRLPPPPPSHQNRKGPPPPPGSAAPAVKAPPPPPVPLPPLMPGPPPPGALPVQPPPMPLMGGVPMRSHPRLAGYYQMLALRVPAEVIKEKMRSDGYQPEWLDTPDAVSPSALPSRKRDMYDSD
InterPro domains: - IPR019309: WASH complex subunit 3 (family) [10-235]
Interaction partners: - WASH complex subunit strumpellin
- Heat shock factor binding protein
- WASH complex subunit 7
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Nucleobindin 1 (Q9VVK7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MVQNVALLGLALIAISASIVALPVTQNKKDHKEAAESSTPATADVETALEYERYLREVVEALEADPEFRKKLDKAPEADIRSGKIAQELDYVNHHVRTKLDEIKRREVERLRELANQAYELSNDIDRKHLKVSQHLDHDNEHTFEIEDLRKLIQKTSDDLAEADRKRRGEFKEYEMQKEFEREAQKKEMDEESRKKFETELKEKEEKHKDHEKLHHPGNKAQLEDVWEKQDHMDKNDFDPKTFFSIHDVDSNGYWDEAEVKALFVKELDKVYQSDLPEDDMRERAEEMERMREHYFQETDMNHDGLISIDEFMVQTNKEEFQKDPEWETIDRQQQYTHEEYLEYERRRQEEVQRLIAQGQLPPHPNMPQGYYAAPPPGGVAYQQAPPGAQLHYQHPDQVHAQQQQQYAQQQQQYAQQYQQQQYGNGQQPVQLQPNQVYQHAGQIPQQQQPVYQNQPVYQQQQPVYQQQQPVQQQQKPVQQPVQQQQQPVQQQQQPVQQQQQTVQQQQPVQQQQQTVQQQQPVQQQQQTAQQQPVAQQQIHNQSPPPVLNQQVPVQQQQKQHQESLNQQH
InterPro domains: - IPR040250: Nucleobindin (family) [5-504]
- IPR011330: Glycoside hydrolase/deacetylase, beta/alpha-barrel (homologous_superfamily) [306-383]
- IPR011992: EF-hand domain pair (homologous_superfamily) [224-314]
- IPR057576: NUCB1-like, N-terminal domain (domain) [19-156]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [300-312]
Interaction partners: - Uncharacterized protein
- Uncharacterized protein, isoform B
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0005509 (calcium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0000003 (reproduction), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0019953 (sexual reproduction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0042742 (defense response to bacterium), GO:0050829 (defense response to Gram-negative bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005576 (extracellular region), GO:0005615 (extracellular space), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Glycophorin-E (P15421)
Organism: Homo sapiens (Human)
Function: This protein is a minor sialoglycoprotein in human erythrocyte membranes.
Subcellular location: Membrane; Single-pass type I membrane protein.
Sequence: MYGKIIFVLLLSGIVSISASSTTGVAMHTSTSSSVTKSYISSQTNGITLINWWAMARVIFEVMLVVVGMIILISYCIR
InterPro domains: - IPR001195: Glycophorin (family) [1-45]
Interaction partners: - Glycophorin-C
- Glycophorin-B
- Band 3 anion transport protein
- Kell blood group glycoprotein
- Alpha-hemoglobin-stabilizing protein
- FRAS1-related extracellular matrix protein 3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhesion), GO:0098609 (cell-cell adhesion), GO:0098742 (cell-cell adhesion via plasma-membrane adhesion molecules), GO:0007157 (heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Protein kinase, putative (Q387Y1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MLLDFVLKYVRGTHPADSEDASKEGSPSAASAYGGKDRKHHPPAEGHRSPPDENVSGNEQGRGIMTLLPKVPSAESVRDKPFYSNGSGHGERRELDGHEKESSVDGKHRQHRSHVLPSMDMDRAPSQFSASGSRQLEGPHGVNCAQVTEQSLEVHDPNDGVDRCHDRSGTGTAHDNNRLAADQIGCTATVAEELRAHRSTTPIKIVNAAAQNVEDDIDDDNEVVGNALVKPMTPQSYSSLMFNSDFRKLNYKEDDIKRRIAVGEGRSLLILQNRGVSCDALSAIPALERHVSDARSCPARSVQSSECAGGVLTSSPRKEEPQRERNFHSEKRPPTADTDGQTICTCGLTVGSSPTEQFSCPGGAAEDSFNRKTCKIHGTNLGCRAHSSELISEWVSECIPPEPVELINVNAGRPRVNVLKKGVINCCVAVRKSLDDAKMMLNNKYVIYFRWCLGVGSSSKVFLCYNLHEKAFYAMKVYNRGRLRRKGFGANCALNNVRREIDIMKKLRHPNILSLVEVIDDPFSRKIYLVLELAEKGAVMTLEGDGTVVPSVSGAALPEEEVARAIRSVVEALIYVHDLGIVHRDVKPQNILLDAEECVKLSDFGVSIMVDGCTSPVPREGTVAFLPPEMLASSEVRVALSDAASHKDTSIGSTNSHQVCSRMNDELPVKTLPEGEREEIGSLQTTDTSVRTQNDNASVSVGSECKQVASTGVASLSGSNNPGCEVSPSDCAGLPACDPTGTPVADFFKADVFALGVTTFVLLMGRLPWLARSSRSQMKAINAQPDPFEEPLRKAYGCPSGEGLKGPTLCNRSLHGSEPPESSAIFLEGTTERTASQQMFSSSSCGRFLASNDADTLDHHVSRSSTKPDCTDWCNSGMSRVSREDEVGAQLLASSPTQCAIGGEWKDSKLLQSSEVGGSPRAHEEADGAQRSPYGHTNTSMRVCCGCRSSSNTATVPTTSFGSLSEAGKAPVSRENKPEFSAVSCFSQPNAAGEATPFRRTHSPSKFPLGRRSTSVFVSNNSSLHSWRIQEGHQPHAGDAVLNEDLEGSLTSDANFPLSAGREFTFPLCQHCATCNNTNNGPYTESGVGDTMSGEQTSGSKMEVPERRGLPETDTHKCISADAIEFVRSCLRINPMERSTMKELYEMPWLQKGR
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [441-1152]
- IPR017441: Protein kinase, ATP binding site (binding_site) [453-476]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [581-593]
- IPR000719: Protein kinase domain (domain) [447-1150]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Rifin (Q8IK38)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Not known
Sequence: MKVHYINILLFSLPLNILEHNPWNHYMKPHTYTNRSLCECELYELANYDNDPQMKEVMENFIKQTQQRFHEYDERLQSKRKQYKDKCDKEIQKIILKDKLEKQMAQQLTTLDPNITTEDIPTCVCEKSLADKTEKFCLNCGKTMGGVAPGWGLVSGLGYAGWSHYAATTLVKIATDAGIAEGLKVGLTKVTEIVTQLSSSTEVAIPTIDVLTNLTTGISADNVTLLGIFKTINIGMKGEFDTDTYALFSTWVQNIATTPKSYMGRYLTEAEEVTKAFADAQTRVLTQAGNVTSNLTTGITVSIIAIVVIVLVMLIIYLILRYRRKKKMKKKLQYIKLLKE
InterPro domains: - IPR006373: Variant surface antigen Rifin (family) [1-340]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response), GO:0042783 (evasion of host immune response), GO:0020033 (antigenic variation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0033643 (host cell part), GO:0043657 (host cell), GO:0033644 (host cell membrane), GO:0020002 (host cell plasma membrane)