Protein: Breast cancer susceptibility protein (Q8QFV6)
Organism: Gallus gallus (Chicken)
Function: Not known
Sequence: MAYKSGKRPTFFEVFKAHCSDSDLGPISLDWFEELSSEAPPYEPKLLGEPEGPIGWFDQTFKTPKAKSSTDSQLASTPLIFKEQNTMPPFSSPGKELDQKKMETSRENLLSPSMAGRKTDQENQILASPHGICHNYTAASPAIVRNPCRTPQRSNIPGPYGSLFCTPKFLEIPTPKRISESLGAEVDPEMSWTSSLATPPTLGVTVIIARENDSISGAKQQDERAEIVLHNFLSEDDGYTAKNDTSLLSIPETVKLNARDDIKDLESEVLDGLFGETNSFEDSFNLPAESSGILLSPRALDAIEKCEIKIDEAQEKSDVLSEQHRRRKSTISQEVKAANWTEKSCCVEVKDSIIQNTNEDIMDSKDNCLLGREKELEYLRIAGNLQDNRTQKSSVNEKLVKDVLSSSSQWSQLNLSGLDVTHLEMSICSSPQSDSCREKGLEEKSVLMTKDDAVETSLLNTSGLRNAQELSSASLSENGSDTKISKNNPMSEITPVKPVCASPKLVKGYAHEEVSGMSFLNCSSFLIESTNVMEYSVVYNSTFSTHLKATSQSVVTDVLSHPLICSAASPDNCSDLHLRNTENTLRKSNFKSLNMLSRLRKKSKRFIYTINNTLVYQEENVQKEVTSESPDNPVLTHLESDLHEFKDCQVATDDCLLSAERQSNIKENNLNTLTIKVDIMDNSSDNSVNNRLKQELSESGKNAREYQPATSFKCLKASHTESEDTTDCLNSGRISNIKHKVLTSAYLMARRHSRLFPEDCCLRKGKNDTYTVSNVNSRAAVPWSPKGQPPQSSPSCSDCLIDMHHGTAFVTNSKFNNTLSHIKFGMNRVSSNSCNKISADKRRASDQLSVAECREIVAPLGINCLENNSTSLKQRGKEDVDENQETLSIKSSENRQAAAWNNESIEVAEEFLDCIDNSLNEVVSEEDRQVAPVYFNTKPIESLEHKGKSSGDLNACSSSLSFGGFQTASNKQIKFSESSIAKGKMLFKDIENEFEFFEASSMERVRNFSNRVQKENIFSSDLESKTGSTSSGLQTRCMQYIPRKVDLCKNSPRNQLSVQEPNQSLTASQEAEIAELSNILEETGSQFEFEFTQFRKQSNMIQSHIQQFGATNVENASEAGGDTNFYSTLKSENHVINDEYCSKLKNENECKMVEYEKEDTVVFHKNKRKVTFTNLDRNESRISSHESCPVPLRDSFSNFVGFTSAGGKKINISKAALTRSAELFKDLDDDNFLFKSSGTNTRCCNSDGRVSSNWNFLRCQTKEDEGGILCVPNIKSVGPISHHSEKKYAENISSPCKENTENWTEILSDNVDFSCTNGGYSASGMRNSPSSFKKPHQNCKNSDQFLNQGNSEVEGCLQEDTSYLICLGDNITSAEEHDLNVSDEMENLSPNQKEDRKQEDEHLLLNRQAADTDAVSISDSSFRSSLRDLNVRCGERDTDVSEKSSKQKTNSVSVEGEDSTYKNLFVSESEIKIGSNQRHQVPSEQEMDVDKNKVKGTYLTGFCTASGKKITIADGFLAKAEEFFSENNVDLGKDDNDCFEDCLRKCNKSYVKDRDLCMDSTAHCDADVLNFKDKLIPEEPGDRLKQTIEESPIIQAVNHDSIKVGAFINVDEDCERNLAAPCANKEAYVRPGKSEVQSLPVHGNNSLSRTLLLEDRKQFAERDVEYSATKRDNSESKPDSSLKCATSLHLTKVSSHLADNSVPGGIIQTVSAEDSCKSNQSFLLPRGSVPRSTSPYLNCGNKEIDLKRLNEPCSNTDSFTNTVDNAHQEQSEFDLPEDETNLTCLQETSLTAESQKSDLKQVFSTAKGKAVSVSESALASIRQMFQTDCDASVKSEIETKSGTNQTAIAGSSSFTIHAGGPGFATFLDTRKSEMNVAAPHFINGNGNLIENNHQGANMFADADSVPGFQMQCFEQKSKLLGHFPVPDKQMEQSGPSGNLGFFSTASGKPVQLSEESLKKARQLFSEMEGSHSSGLQDAHLLEDVEKSNNRGEVFPREMQLLLPRGKENASTDKISSPALGFSTASGKQVTISESAYQKAKAILKEADGFLSSELGVTNELCEIKESGQHAEYLTGKVISESKTEKSCSEELDLKSIHPEKMKSLPSTHRVKITEYVPHSKRNSQSAPFKNSFEQEETRFFRKGELNLGIKTESESDLCSATSKAEINIFQTPKDYLKTEAVESAKAFMEDDLSDSGVQVKSAQSFGKMSDNFQNKPFGKRHLDEKDSHGEPPIKRQLLLEFEKMKIPPKSVKPLKSTPDGIFKDRRKFMYHVPLKPVTCQPLGTTKERQEVRNPTLTLPDQDLKGFKSIPAVFQHCALRQSSSGASGLFTPHKAVAKDSEETRSLCKSGKAVKTFVPPFKTKLTLSTGEQGGSKRCHSPIRNSVMEERELNQIPVEQNSAEARDHQSCILHAAVTDIENDNLVTSNMMANLHCARDLQEMRIKKKYRQNISPQPGSLYVTKTSARNRISLKTAVEEETPSFHSTEKLYTYGVSKHCIQVNSTNAESFQFLIEEFFSKEYLLAGNGIQLADGGWLIPTDEGKAGKKEFYRALCDTPGVDPKLITEAWVYNHYRWIVWKLAAMEVCFPHKFANRCLTPETVLLQLKYRYDLEIDKSKRSAIKKITERDDAAGKTLVLCVSKVLSLNTAVSPSNSNNNTEGEKAAAIIEVTDGWYGIRALLDPPLKAFLHRRRLTVGQKIIVHGAELIGSPNGCTPLEAPDSLMLKIAANSTRCARWYTKLGFHRDPRPFPLPLSSLYSEGGTVGCIDVVVQRTYPIQWMEKTSAGSYVFRNSRAEEREAAKHAEDQQKKLEALFAKIQAEFEKHEERNCRRAPRSRIVTRQQIHNLQDGAELYEAIQNAADPSYMEGYLSEDQLKALNAHKQLMNDKKQTRIREEFKKAVESAEQEKHGFSKRDVSTVWKLFVIDYRKQEKHRGVILSIWRPLLDVCSLLKEGSRYRICQLSTSQSKGRSDSTNVQLSATKKTRYLQLSVSQKMLQQIFFPRKALKFTSLLDPSYQPPCAEVDVVGVVISISRTGFSNMVYLSDESYNLVAIKIWADLRHFAIEDIVVRCSFIAASNLQWQSEFRSEIPVLLAGDLSAFSASPKENHLQEKFNELRRMIENVDSFCSDAESKLMNLLQRNCSLTPILPKRCGLECSSPSCNSGLYAEDRSSISSKIETKHPSPLSASTPNTKLFPQGSAITPSSAVSSENHPRNSKKRKAVDFLSCIPAPPPLTPLCSIISPSLKKAFQPPRRLGSQHSKLSKETNPNAGCVTPSRKLREAVQLPDNDLVADEELAMINTQALINTVPEEKKMDYVNEDSTRATNLSGDTRATNLSRDMRAPNLSGDLSSKNSSRSAKEANSSLKSSSEGADALQKDTEEPEGSLSIRRVLQRRKSRKCY
InterPro domains: - IPR015252: Breast cancer type 2 susceptibility protein, helical domain (domain) [2429-2614]
- IPR015205: Tower domain (domain) [2777-2818]
- IPR002093: BRCA2 repeat (repeat) [958-2048]
- IPR015188: BRCA2, OB3 (domain) [3000-3136]
- IPR015525: Breast cancer type 2 susceptibility protein (family) [1-3396]
- IPR048262: BRCA2, OB2 domain (domain) [2750-3002]
- IPR015187: BRCA2, OB1 (domain) [2617-2742]
- IPR055077: BRCA2, TR2 domain (domain) [3207-3283]
- IPR036315: BRCA2 helical domain superfamily (homologous_superfamily) [2425-2615]
- IPR012340: Nucleic acid-binding, OB-fold (homologous_superfamily) [2616-3143]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0051179 (localization), GO:0009987 (cellular process), GO:0051641 (cellular localization), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0033036 (macromolecule localization), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0006810 (transport), GO:0070727 (cellular macromolecule localization), GO:0016043 (cellular component organization), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0045184 (establishment of protein localization), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0090304 (nucleic acid metabolic process), GO:0015031 (protein transport), GO:0072594 (establishment of protein localization to organelle), GO:0006259 (DNA metabolic process), GO:0071702 (organic substance transport), GO:0043933 (protein-containing complex organization), GO:0008104 (protein localization), GO:0006996 (organelle organization), GO:0022607 (cellular component assembly), GO:0006606 (protein import into nucleus), GO:0033365 (protein localization to organelle), GO:0033365 (protein localization to organelle), GO:0072666 (establishment of protein localization to vacuole), GO:0065003 (protein-containing complex assembly), GO:0006310 (DNA recombination), GO:0065003 (protein-containing complex assembly), GO:0071824 (protein-DNA complex subunit organization), GO:0006310 (DNA recombination), GO:0051259 (protein complex oligomerization), GO:0000725 (recombinational repair), GO:0065004 (protein-DNA complex assembly), GO:0072665 (protein localization to vacuole), GO:0051260 (protein homooligomerization), GO:0000724 (double-strand break repair via homologous recombination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)