Protein: FI23202p1 (Pebble) (Q9U7D8)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MEMETIEEQSKCEMSITTLPTRICLVGGVGQDADTLQAAESFGLPIVTSDTGLDILGESSDWRTFYVLDDFEGASFEAIHKQKECILGPPALKYAAEMKQTLGQNSRPIYNYAMRGVVTCFTGIRKKDELTKLVNLIHSMGGCIKKDLNTKTTHLICNHSGGEKYQYAKTFRLTVVRPAWVFAAWADRNSLEFDATQENFTKTHRLKAFEGQKICFFGFPVEEHQHMVDVLLENGGVCAELDDPECSHVVVDEHTTLTKPEPKNNHTHILKSDWFWYTIQNGYANEMDYLFGDYLDSITNTPNTDRRDSLPISFNKRKRKRFSQRIQLEGTPLGSGKRRSSVSDAGLLSVSNSLFDCTTSPDKLESDKLLHAEPEASDATPAKKSMRFNHFMDFYTTESNYVGILDTILNLFKNKLEELAETNDPLLNKSEIKTIFGNFLPIHEVHQSMLEHLRKLHANWREDCLIGDIIIQHRDELIKAYPPYVNFFEQMKEQLQYCDREYPRFHAFLKINQTKPECGRQGLQDLMIRPVQRLPSISLLLNDILKHTTSGNADHGRLEEALKAIKQVTLHINEDKRRTESRMAIFDIFNDIEGCPAHLVSSNRSFILKCEVNELSDSLSGRGDSLVLYLFSDSIELCKRRSKGFNTAKSPSTAKTHKHLKLISLNTIRLVIDISDSPRAFGLLLRGDKEKLYTFTISDEETDKSVYVKKLCNQIAAHTCRTDADKLLICRTSQELEVDISDVNVSTLSKAFKLAAKTRLKVGRAFSFNKTPNKLKRAVSTMMTSPFGSTNSLTPASQLAQMRLASCTNINEVDDEDCASMRSSSPSTQSEMLVVPPLSVQPTRKNKAVVGRI
InterPro domains: - IPR000219: Dbl homology domain (domain) [386-575]
- IPR049395: ECT2, PH domain (domain) [601-716]
- IPR049396: ECT2, BRCT0 domain (domain) [57-110]
- IPR026817: Guanine nucleotide exchange factor Ect2 (family) [1-848]
- IPR035899: Dbl homology (DH) domain superfamily (homologous_superfamily) [372-593]
- IPR036420: BRCT domain superfamily (homologous_superfamily) [15-292]
- IPR001357: BRCT domain (domain) [109-282]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [586-753]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0008289 (lipid binding), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0005102 (signaling receptor binding), GO:0005543 (phospholipid binding), GO:0051020 (GTPase binding), GO:0035091 (phosphatidylinositol binding), GO:0030215 (semaphorin receptor binding), GO:0031267 (small GTPase binding), GO:1901981 (phosphatidylinositol phosphate binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0051641 (cellular localization), GO:0007275 (multicellular organism development), GO:0023057 (negative regulation of signaling), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0090130 (tissue migration), GO:0051321 (meiotic cell cycle), GO:0022402 (cell cycle process), GO:0007049 (cell cycle), GO:0051301 (cell division), GO:0071840 (cellular component organization or biogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0033036 (macromolecule localization), GO:0050793 (regulation of developmental process), GO:0065008 (regulation of biological quality), GO:0051235 (maintenance of location), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0008037 (cell recognition), GO:0051651 (maintenance of location in cell), GO:0023051 (regulation of signaling), GO:0030029 (actin filament-based process), GO:1903046 (meiotic cell cycle process), GO:0007017 (microtubule-based process), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0032506 (cytokinetic process), GO:0061982 (meiosis I cell cycle process), GO:0009968 (negative regulation of signal transduction), GO:0000910 (cytokinesis), GO:0010648 (negative regulation of cell communication), GO:0048729 (tissue morphogenesis), GO:0008038 (neuron recognition), GO:0044085 (cellular component biogenesis), GO:1903047 (mitotic cell cycle process), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0007051 (spindle organization), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0032507 (maintenance of protein location in cell), GO:0009966 (regulation of signal transduction), GO:0007442 (hindgut morphogenesis), GO:0000226 (microtubule cytoskeleton organization), GO:0030036 (actin cytoskeleton organization), GO:0035295 (tube development), GO:0001704 (formation of primary germ layer), GO:0007059 (chromosome segregation), GO:0048598 (embryonic morphogenesis), GO:0061983 (meiosis II cell cycle process), GO:0009888 (tissue development), GO:0044837 (actomyosin contractile ring organization), GO:0010646 (regulation of cell communication), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0070727 (cellular macromolecule localization), GO:0009790 (embryo development), GO:0016043 (cellular component organization), GO:0007509 (mesoderm migration involved in gastrulation), GO:0051128 (regulation of cellular component organization), GO:0033206 (meiotic cytokinesis), GO:0090066 (regulation of anatomical structure size), GO:0000278 (mitotic cell cycle), GO:0045185 (maintenance of protein location), GO:0016477 (cell migration), GO:0035239 (tube morphogenesis), GO:0072001 (renal system development), GO:0048619 (embryonic hindgut morphogenesis), GO:0032535 (regulation of cellular component size), GO:0022604 (regulation of cell morphogenesis), GO:0060562 (epithelial tube morphogenesis), GO:0030030 (cell projection organization), GO:0031344 (regulation of cell projection organization), GO:0055123 (digestive system development), GO:0001707 (mesoderm formation), GO:0007443 (Malpighian tubule morphogenesis), GO:0000915 (actomyosin contractile ring assembly), GO:0007369 (gastrulation), GO:0030111 (regulation of Wnt signaling pathway), GO:0002009 (morphogenesis of an epithelium), GO:0048546 (digestive tract morphogenesis), GO:0001667 (ameboidal-type cell migration), GO:0048666 (neuron development), GO:0022607 (cellular component assembly), GO:0022008 (neurogenesis), GO:0050770 (regulation of axonogenesis), GO:0051225 (spindle assembly), GO:0007414 (axonal defasciculation), GO:0061326 (renal tubule development), GO:0007110 (meiosis I cytokinesis), GO:0007399 (nervous system development), GO:0061640 (cytoskeleton-dependent cytokinesis), GO:0030866 (cortical actin cytoskeleton organization), GO:1902410 (mitotic cytokinetic process), GO:0048332 (mesoderm morphogenesis), GO:0000912 (assembly of actomyosin apparatus involved in cytokinesis), GO:0030178 (negative regulation of Wnt signaling pathway), GO:0072002 (Malpighian tubule development), GO:0008104 (protein localization), GO:0007498 (mesoderm development), GO:0060429 (epithelium development), GO:0006996 (organelle organization), GO:0031032 (actomyosin structure organization), GO:0048565 (digestive tract development), GO:0030182 (neuron differentiation), GO:0000281 (mitotic cytokinesis), GO:0070925 (organelle assembly), GO:0008360 (regulation of cell shape), GO:0042074 (cell migration involved in gastrulation), GO:0008078 (mesodermal cell migration), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0007415 (defasciculation of motor neuron axon), GO:0120036 (plasma membrane bounded cell projection organization), GO:1902407 (assembly of actomyosin apparatus involved in mitotic cytokinesis), GO:0008361 (regulation of cell size), GO:0061525 (hindgut development), GO:1903475 (mitotic actomyosin contractile ring assembly), GO:0007010 (cytoskeleton organization), GO:0061333 (renal tubule morphogenesis), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0090090 (negative regulation of canonical Wnt signaling pathway), GO:0060828 (regulation of canonical Wnt signaling pathway), GO:0061564 (axon development), GO:0045792 (negative regulation of cell size), GO:0030865 (cortical cytoskeleton organization), GO:0140694 (non-membrane-bounded organelle assembly), GO:0010975 (regulation of neuron projection development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0032153 (cell division site), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0098590 (plasma membrane region), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0032154 (cleavage furrow), GO:0005938 (cell cortex), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)