Protein: Cyclin-D3-1 (Cyclin-delta-3) (Cyclin-d3) (G1/S-specific cyclin-D3-1) (CycD3;1) (P42753)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the control of the cell cycle at the G1/S (start) transition. Activates the G1/S phase transition in response to cytokinin hormone signal, but declines in response to sucrose starvation leading to G1 arrest. Involved in the induction of mitotic cell division. Plays an important role in the switch from cell proliferation to the final stages of differentiation during plant development. May not be involved in the activation of cell cycle in the root apical meristem (RAM) in the early phase of seed germination. Promotes divisions in the guard cells (GCs) after the guard mother cells (GMC) symmetric division.
Sequence: MAIRKEEESREEQSNSFLLDALYCEEEKWDDEGEEVEENSSLSSSSSPFVVLQQDLFWEDEDLVTLFSKEEEQGLSCLDDVYLSTDRKEAVGWILRVNAHYGFSTLAAVLAITYLDKFICSYSLQRDKPWMLQLVSVACLSLAAKVEETQVPLLLDFQVEETKYVFEAKTIQRMELLILSTLEWKMHLITPISFVDHIIRRLGLKNNAHWDFLNKCHRLLLSVISDSRFVGYLPSVVAAATMMRIIEQVDPFDPLSYQTNLLGVLNLTKEKVKTCYDLILQLPVDRIGLQIQIQSSKKRKSHDSSSSLNSPSCVIDANPFNSDESSNDSWSASSCNPPTSSSSPQQQPPLKKMRGAEENEKKKPILHLPWAIVATP
InterPro domains: - IPR048258: Cyclins, cyclin-box (conserved_site) [87-118]
- IPR004367: Cyclin, C-terminal domain (domain) [189-310]
- IPR013763: Cyclin-like domain (domain) [92-281]
- IPR039361: Cyclin (family) [45-292]
- IPR006671: Cyclin, N-terminal (domain) [85-186]
- IPR036915: Cyclin-like superfamily (homologous_superfamily) [56-283]
Interaction partners: - Cyclin-dependent kinase A-1
- Retinoblastoma-related protein 1
- Cyclin-dependent kinase B1-1
- Cyclin-dependent kinase B2-1
- Cyclin-dependent kinase inhibitor 1
- Cyclin-dependent kinase B2-2
- Transcription factor E2FA
- Cyclin-dependent kinase B1-2
- Cyclin-D3-3
- Cyclin-D3-2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0048869 (cellular developmental process), GO:0050793 (regulation of developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0003006 (developmental process involved in reproduction), GO:0009791 (post-embryonic development), GO:0048316 (seed development), GO:0048608 (reproductive structure development), GO:0010374 (stomatal complex development), GO:0009888 (tissue development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0010440 (stomatal lineage progression), GO:0090558 (plant epidermis development), GO:0061458 (reproductive system development), GO:1905421 (regulation of plant organ morphogenesis), GO:0090627 (plant epidermal cell differentiation), GO:0010154 (fruit development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)