Protein: RE35509p (Uncharacterized protein, isoform C) (Q9VGG9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|PIRNR:PIRNR038901}.
Sequence: MKRRSQTRAEQAVPPAKTTKENSGSLTVSQLSSDVIWQLASQYWTPDTKADHLPYSAKIIERIYNEEIGDGGGHSARRINMLEFSQYLEQYLWPHYQRETATHAHLMSIVIMANEKFRERVEVWTVFEKLPDQYPAFFRHVLESCLPSKKAKEASSTLRERTALLMFINHCFNSMEIELCREQAKRLVSLSMWHCLQPRRREQELREVPEWRKYWKRLLKKEKDSKPEVLWERHFMQNLIIDFLHILESIPAEGEVPRNVVHYCERFLEFIIDLEALLPTRRFFNTVLDDCHLIVRALLSPLVRREEGKLFGQLLDMLKFYTRFEINDVTGSSLTDHDMTQLHYKKITSLQRAVFAKFPSLRVFALSNVATVDNRESLEQHFGGLDGKGLLQIATFLNLVPEEVVSPLDWHRVDEQFLRELLITRHERRCSQLEALNEMPLYPTEQIIWDENVVPSEYYSGDSCLALPKLNLQFLTLHDYLLRNFNLFRLESTYEIRQDIEDAVSRMLPWKSEDGDVVFGGWARMALPIASFAVVEVAKPHLGEKKPSRVRADVGVTLSVRREIKAEWENLRKHDVCFLITVKPTQPYGTKYKHREPFVPQVGLVSVRGCEVEGMLDANGRVIEDGPEPRPQLQGENRCYRVWLDSNQYRLDMDDLQEGADDVYESFNILMRRKPKENNFKAVLETIRHLMNTECVVPPWLHDILLGYGDPGAAHYSNMPNQERSLEFNDTFMDYNHLEASFPQYNLKCEVPVENRQPPFRLIFEDVPIQKESDGEDPEEKPEEKLTKSILVQPYKYEARGPYPSDKPKQNSIRFTPTQVEAIRAGMQPGLTLVVGPPGTGKTDVAVQIISNIYHNHPNQRTLIVTHSNQALNQLFEKIMALDIDERHLLRLGHGEEALETEKDYSRYGRVNYVLAKRMDLLSQVQKLQEALGVSGDNAYTCETAGYFYLYNVMARWEKFQSQISVHKGEADAEKLRAEFEKEFPFGKFFADAPQPLFKGANYDELMDIACSNFRYISDIFNELEEFRAFELLRTGLDRSKYLLVKEAKIIAMTCTHAALKRKELVNLGFRYDNILMEESAQILEIETFIPLLLQNPLDGLNRLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRLVRLGVPTVDLDGQGRARASICSLYKWRYKKLEDLQHIFERDEYKQANPGFVHDYQLINVEDFKGVGESEPNPYFYQNLAEAEYIVAVYMYMRLLGYPAAKISILTTYNGQKHLIRDVINARCGNNPLIGWPHKITTVDKYQGQQNDYILISLVRTKAVGHLRDVRRLVVAMSRARLGLYVFGRVSLFKNCLELQQTFKLRPLKLSLVPEDKFPTDRLASAAVASQDIKTVENMSEMAQFVYERYMAKMEELKGTLPSEEELEAMRNQLLQEDEESVPEASEEPPEKRAAKEEPLSKKKTTEAFKPTPILNEINVDDTEMGQREQIEEEATDQDKTQESAPAEES
InterPro domains: - IPR041677: DNA2/NAM7 helicase, helicase domain (domain) [818-1122]
- IPR047187: Upf1-like, C-terminal helicase domain (domain) [1156-1337]
- IPR048966: RNA helicase aquarius, beta-barrel (domain) [509-673]
- IPR045055: DNA2/NAM7-like helicase (family) [425-1332]
- IPR026300: CWF11 family (family) [16-1463]
- IPR041679: DNA2/NAM7 helicase-like, C-terminal (domain) [1131-1322]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [768-1339]
- IPR032174: RNA helicase aquarius, N-terminal domain (domain) [36-429]
- IPR048967: RNA helicase aquarius, insertion domain (domain) [721-806]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0004386 (helicase activity), GO:1901363 (heterocyclic compound binding), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0097159 (organic cyclic compound binding), GO:0008186 (ATP-dependent activity, acting on RNA), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0140098 (catalytic activity, acting on RNA), GO:0003724 (RNA helicase activity), GO:0003723 (RNA binding), GO:0003727 (single-stranded RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0008380 (RNA splicing), GO:0006397 (mRNA processing), GO:0016071 (mRNA metabolic process), GO:0000398 (mRNA splicing, via spliceosome), GO:0000375 (RNA splicing, via transesterification reactions), GO:0000377 (RNA splicing, via transesterification reactions with bulged adenosine as nucleophile)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000974 (Prp19 complex), GO:1902494 (catalytic complex), GO:0140513 (nuclear protein-containing complex), GO:0005681 (spliceosomal complex), GO:0043229 (intracellular organelle), GO:0071013 (catalytic step 2 spliceosome), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0071011 (precatalytic spliceosome), GO:0005634 (nucleus)