wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: F9K20.7 protein (Ubiquitin-specific protease family C19-related protein) (Q9ZVA7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MGSRYASHQLSNGLFVSGRPEQPKEKPPTMSSVAMPYTGGDIKKSGELGKMFDIPTDGTKSRKSGPITGGSSRSGAQSGPVPNATGRMSGNLASAGSNSMKKTNSGPLSKHGEPLKKSSGPQSGGVTRQNSGPIPILPTTGLITSGPITSGPLNSSGAPRKISGPLDYSGSMKTHMPSVVHNQAVTTLAPEDDFSCMKSFPKPVLWLVILIFVMGFLAGGFILGAVHNAILLIVVAVLFTVVAALFIWNISCERRGITDFIARYPDADLRTAKNGQYVKVTGVVTCGNVPLESSFHRVPRCVYTSTCLYEYRGWGSKPANASHRRFTWGLRSAERHVVDFYISDFQSGLRALVKTGNGAKVTPLVDDSVVIDFKPGNEQASPDFVRWLGKKNLTNDDRIMRLKEGYIKEGSTVSVIGVVQRNDNVLMIVPTTEPLAAGWQWSKCTFPASLEGIVLRCEDSSNVDAIPV
InterPro domains: - IPR040339: Uncharacterized membrane protein At1g16860-like (family) [1-468]
Interaction partners: - 26S proteasome non-ATPase regulatory subunit 6 homolog
- 26S proteasome regulatory subunit
- ATP-dependent Clp protease proteolytic subunit 5, chloroplastic
- Nucleobase-ascorbate transporter 2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0048523 (negative regulation of cellular process), GO:0009892 (negative regulation of metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0045912 (negative regulation of carbohydrate metabolic process), GO:0043255 (regulation of carbohydrate biosynthetic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010675 (regulation of cellular carbohydrate metabolic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0032881 (regulation of polysaccharide metabolic process), GO:0010677 (negative regulation of cellular carbohydrate metabolic process), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0006109 (regulation of carbohydrate metabolic process), GO:0032950 (regulation of beta-glucan metabolic process), GO:0032885 (regulation of polysaccharide biosynthetic process), GO:2000112 (regulation of cellular macromolecule biosynthetic process), GO:0010962 (regulation of glucan biosynthetic process), GO:2000113 (negative regulation of cellular macromolecule biosynthetic process), GO:0032951 (regulation of beta-glucan biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: DNA/RNA-binding protein Alba-like domain-containing protein (Q583J0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MPSYPSHDDRQRTKNEGAKEKGQGAENEIRVTARPGSRGYITYALALLRGEEGKPKYDSVKISAMGAAIRSAVGVAEVLKRRVAGLHQTTEISSEVIHDTYEGNDDKTEKKEVERKVSTILITLSLKPLDVNHIGYQAPLPESEVKEEEERSQISRGRGGGGGSRAGGRGAGRGGGSRGGGRGAAGSRGRGRGRGRGGTGGGAHGSQRDGSDLGEGN
InterPro domains: - IPR002775: DNA/RNA-binding protein Alba-like (domain) [27-95]
- IPR036882: Alba-like domain superfamily (homologous_superfamily) [23-142]
- IPR051958: Alba-like nucleic acid-binding (family) [21-203]
Interaction partners: - DNA/RNA-binding protein Alba-like domain-containing protein
- DNA/RNA-binding protein Alba-like domain-containing protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0010467 (gene expression), GO:0042254 (ribosome biogenesis), GO:0042274 (ribosomal small subunit biogenesis), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0034470 (ncRNA processing), GO:0030490 (maturation of SSU-rRNA), GO:0006364 (rRNA processing), GO:0034660 (ncRNA metabolic process), GO:0016072 (rRNA metabolic process), GO:0000462 (maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA))
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0035770 (ribonucleoprotein granule), GO:0036464 (cytoplasmic ribonucleoprotein granule), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0010494 (cytoplasmic stress granule), GO:0043232 (intracellular non-membrane-bounded organelle)
Protein: Pentatricopeptide repeat-containing protein At1g79490, mitochondrial (Protein EMBRYO DEFECTIVE 2217) (Q9SAK0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Mitochondrion {ECO:0000305}.
Sequence: MIRGRTAKVIPRNVIFTLSRSSISESPLISPSRINPKLAGSFSFNIRLLSYFTVRNGFCPDCSVPRDPNFVGLTTQCRSIVRRFCSEKIGSSESSGWTEEVEYLDESGSVLHSGKGIRSVEPGLDDHVMVGGLKKPYMNASSVAKIVEVVQRWKWGPELETQLDKLQFVPNMVHITQSLKIVKEVDAALSLFRWAKKQPWYLPSDECYVVLFDGLNQGRDFVGIQSLFEEMVQDSSSHGDLSFNAYNQVIQYLAKAEKLEVAFCCFKKAQESGCKIDTQTYNNLMMLFLNKGLPYKAFEIYESMEKTDSLLDGSTYELIIPSLAKSGRLDAAFKLFQQMKERKLRPSFSVFSSLVDSMGKAGRLDTSMKVYMEMQGFGHRPSATMFVSLIDSYAKAGKLDTALRLWDEMKKSGFRPNFGLYTMIIESHAKSGKLEVAMTVFKDMEKAGFLPTPSTYSCLLEMHAGSGQVDSAMKIYNSMTNAGLRPGLSSYISLLTLLANKRLVDVAGKILLEMKAMGYSVDVCASDVLMIYIKDASVDLALKWLRFMGSSGIKTNNFIIRQLFESCMKNGLYDSARPLLETLVHSAGKVDLVLYTSILAHLVRCQDEDKERQLMSILSATKHKAHAFMCGLFTGPEQRKQPVLTFVREFYQGIDYELEEGAARYFVNVLLNYLVLMGQINRARCVWKVAYENKLFPKAIVFDQHIAWSLDVRNLSVGAALIAVVHTLHRFRKRMLYYGVVPRRIKLVTGPTLKIVIAQMLSSVESPFEVSKVVLRAPGELVMEWFKKPIVQQFLLNEIPSRSDILMHKMNVMFPSSAPELRSMSPPKPLMSSKAF
InterPro domains: - IPR002625: Smr domain (domain) [707-786]
- IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [158-632]
- IPR002885: Pentatricopeptide repeat (repeat) [245-486]
- IPR033443: PROP1-like, PPR domain (domain) [246-398]
Interaction partners: - Pentatricopeptide repeat-containing protein At2g17033
- Protein-S-isoprenylcysteine O-methyltransferase A
- Jacalin-related lectin 33
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0008380 (RNA splicing), GO:0000375 (RNA splicing, via transesterification reactions), GO:0000377 (RNA splicing, via transesterification reactions with bulged adenosine as nucleophile), GO:0000373 (Group II intron splicing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Chaperonin GroEL (EC 5.6.1.7) (60 kDa chaperonin) (Chaperonin-60) (Cpn60) (Q9KJ23)
Organism: Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533)
Function: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00600}.
Sequence: MAKEIKFSENARHSLLKGVDKLADTVKTTLGPKGRNVVLEKSYGAPDITNDGVTIAKSIELENHFENMGAKLVSEAAQKTNDIAGDGTTTATVLTQAIVREGMKNVTAGANPVGIRRGIETATKAAVDELHKISHKVSTKDEIAQVASVSSASTEVGNLIADAMEKVGHDGVITIEESKGIDTELSVVEGMQFDRGYLSQYMVTDNDKMEADLDNPYILITDKKISNIQDILPLLQEIVQQGKSLLIIADDVDGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGTVISSDLGLELKDTKIDQLGKAGKVTVTKDSTTIVEGAGSKEAIAERVDQIKKQIADTTSDFDREKLQERLAKLAGGVAVIKVGAATETELKERKYRIEDALNATRAAVEEGYVAGGGTALVDVMKSIQGTVKGDSEDAETGVKIVMKALGAPVRQIAENAGKDGAVILDHLEHEDPEVGYNAATNKWENMVKAGIIDPTKVTRSALQNAASIAALLLTTEAVVADAPEDDKNQAPAAPNPGMGMGM
InterPro domains: - IPR027410: TCP-1-like chaperonin intermediate domain superfamily (homologous_superfamily) [136-408]
- IPR018370: Chaperonin Cpn60, conserved site (conserved_site) [403-414]
- IPR027409: GroEL-like apical domain superfamily (homologous_superfamily) [182-374]
- IPR002423: Chaperonin Cpn60/GroEL/TCP-1 family (family) [22-523]
- IPR027413: GroEL-like equatorial domain superfamily (homologous_superfamily) [1-524]
- IPR001844: Chaperonin Cpn60/GroEL (family) [1-543]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009893 (positive regulation of metabolic process), GO:0051239 (regulation of multicellular organismal process), GO:0019222 (regulation of metabolic process), GO:0051240 (positive regulation of multicellular organismal process), GO:0060255 (regulation of macromolecule metabolic process), GO:0001819 (positive regulation of cytokine production), GO:0001817 (regulation of cytokine production), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0010628 (positive regulation of gene expression), GO:0032677 (regulation of interleukin-8 production), GO:0032757 (positive regulation of interleukin-8 production), GO:0010468 (regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0043226 (organelle), GO:0009986 (cell surface), GO:0005576 (extracellular region), GO:0033643 (host cell part), GO:0043657 (host cell), GO:0043227 (membrane-bounded organelle), GO:0043230 (extracellular organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0020003 (symbiont-containing vacuole), GO:0033655 (host cell cytoplasm part), GO:0030430 (host cell cytoplasm)
Protein: Membrane-spanning 4-domains subfamily A member 4A (CD20 antigen-like 1) (Four-span transmembrane protein 1) (Q96JQ5)
Organism: Homo sapiens (Human)
Function: May be involved in signal transduction as a component of a multimeric receptor complex.
Subcellular location: Membrane; Multi-pass membrane protein.
Sequence: MHQTYSRHCRPEESTFSAAMTTMQGMEQAMPGAGPGVPQLGNMAVIHSHLWKGLQEKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYCNYYGNSNNCHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETASPTPLNEV
InterPro domains: - IPR007237: CD20-like family (family) [65-207]
- IPR030417: Membrane-spanning 4-domains subfamily A (family) [21-217]
Interaction partners: - Membrane-spanning 4-domains subfamily A member 6E
- V-set and immunoglobulin domain-containing protein 4
- Scavenger receptor cysteine-rich type 1 protein M130
- Membrane-spanning 4-domains subfamily A member 10
- Complement C1q subcomponent subunit A
- Complement C1q subcomponent subunit B
- Phospholipid-transporting ATPase ABCA7
- Membrane-spanning 4-domains subfamily A member 6A
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0010942 (positive regulation of cell death), GO:0010941 (regulation of cell death), GO:0043067 (regulation of programmed cell death), GO:0043068 (positive regulation of programmed cell death), GO:0043065 (positive regulation of apoptotic process), GO:0042981 (regulation of apoptotic process), GO:1904037 (positive regulation of epithelial cell apoptotic process), GO:1904035 (regulation of epithelial cell apoptotic process), GO:1904037 (positive regulation of epithelial cell apoptotic process), GO:2000351 (regulation of endothelial cell apoptotic process), GO:2000353 (positive regulation of endothelial cell apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005615 (extracellular space), GO:0071944 (cell periphery), GO:0005576 (extracellular region), GO:0070062 (extracellular exosome), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043230 (extracellular organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:1903561 (extracellular vesicle)
Protein: RNA binding motif protein 17 (Q5W010)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MSLYDDLGVETSDSKTEGWSKNFKLLQSQLQVKKAALTQAKSQRTKQSTVLAPVIDLKRGGSSDDRQIVDTPPHVAAGLKDPVPSGFSAGEVLIPLADEYDPMFPNDYEKVVKRQREERQRQRELERQKEIEEREKRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPRS
InterPro domains: - IPR040052: Splicing factor 45 (family) [1-221]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0008380 (RNA splicing), GO:0006397 (mRNA processing), GO:0016071 (mRNA metabolic process), GO:0000398 (mRNA splicing, via spliceosome), GO:0000375 (RNA splicing, via transesterification reactions), GO:0000380 (alternative mRNA splicing, via spliceosome), GO:0000377 (RNA splicing, via transesterification reactions with bulged adenosine as nucleophile)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Amino acid transporter AVT1C (AtAvt1C) (F4IUW3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Sequence: MNHVPSDQSFYIESEDEDDRKDYVEEDGGSHSDSSDDVYDENQAHIKPSSYTTAWPQSYRQSIDLYSSVPSPGIGFLGNNSMTRFGSSFLSSGLIRRHTPESLPTVTKPLLEEQADEQALPKHRLSSQGLLSPIPSRRGSMRKDEKSSMVSHEIPMSRNSSYGQAVLNGLNVLCGVGILSTPYAAKEGGWLGLMILFVYGLLSFYTGILLRYCLDSESDLETYPDIGQAAFGTTGRIFVSIVLYLELYACCVEYIILESDNLSSLYPNAALSIGGFQLDARHLFALLTTLAVLPTVWLRDLSVLSYISAGGVIASVLVVLCLFWIGLVDEVGIHSKGTTLNLSTLPVAIGLYGYCYSGHAVFPNIYTSMAKPSQYPAVLLTCFGICTLMYAGVAVMGYTMFGESTQSQFTLNLPQDLIATKIAVWTTVVNPFTKYALTISPVAMSLEELIPSRHIRSHWYAIGIRTLLVFSTLLVGLAIPFFGLVMSLIGSLLTMLVTLILPPACFLSIVRRKVTPTQMMLCVLIIIVGAISSVIGSYSALSKIVEKLTN
InterPro domains: - IPR013057: Amino acid transporter, transmembrane domain (domain) [159-540]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0005342 (organic acid transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity), GO:0046943 (carboxylic acid transmembrane transporter activity), GO:0015171 (amino acid transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:0015849 (organic acid transport), GO:0006865 (amino acid transport), GO:0015711 (organic anion transport), GO:0015804 (neutral amino acid transport), GO:0046942 (carboxylic acid transport), GO:0015824 (proline transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0005773 (vacuole), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000325 (plant-type vacuole), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Calaxin (EF-hand calcium-binding domain-containing protein 1) (Q9D3N2)
Organism: Mus musculus (Mouse)
Function: Component of the outer dynein arm-docking complex (ODA-DC) that mediates outer dynein arms (ODA) binding onto the doublet microtubule. Seems to regulate the assembly of both ODAs and their axonemal docking complex onto ciliary microtubules (By similarity). Regulates ciliary and flagellar motility and is required for cilia-driven determination of body laterality.
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:31240264}. Cell projection, cilium {ECO:0000250|UniProtKB:Q9HAE3}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q9HAE3}.
Sequence: MNRKKLQKLTDTLTKNCKHFDKFEVKCLITLFYNLVGDVAERPGVVTGLDRNVFRNILHVTFGMTDDMIMDRVFRGFDKDNDGCISVSEWIHGLSLFLRGTLDEKMKYCFEVFDLNGDGFISKEEMFHMLKNSLLKQPSEEDPDEGIKDLVEITLKKMDHDHDGKLSFVDYEKAVREENLLLEAFGPCLPDPKSQMEFEAQVFKDPNEFNDM
InterPro domains: - IPR011992: EF-hand domain pair (homologous_superfamily) [16-198]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [78-171]
- IPR002048: EF-hand domain (domain) [65-181]
- IPR028846: Recoverin family (family) [10-181]
Interaction partners: - Piercer of microtubule wall 1 protein
- Outer dynein arm-docking complex subunit 2
- EF-hand domain-containing family member C2
- Outer dynein arm-docking complex subunit 4
- Armadillo repeat-containing protein 3
- Outer dynein arm-docking complex subunit 3
- Cilia-and flagella-associated protein 96
- IQ motif and ubiquitin-like domain-containing protein
- Outer dynein arm-docking complex subunit 1
- Piercer of microtubule wall 2 protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030234 (enzyme regulator activity), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0048306 (calcium-dependent protein binding), GO:0043169 (cation binding), GO:0010851 (cyclase regulator activity), GO:0008047 (enzyme activator activity), GO:0030249 (guanylate cyclase regulator activity), GO:0046872 (metal ion binding), GO:0010853 (cyclase activator activity), GO:0030250 (guanylate cyclase activator activity), GO:0005509 (calcium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007017 (microtubule-based process), GO:0007018 (microtubule-based movement), GO:0003341 (cilium movement)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0036477 (somatodendritic compartment), GO:0042995 (cell projection), GO:0097447 (dendritic tree), GO:0120025 (plasma membrane bounded cell projection), GO:0043005 (neuron projection), GO:0030425 (dendrite), GO:0030424 (axon)