Protein: Coatomer subunit alpha (O77285)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|PIRNR:PIRNR003354}. Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004255, ECO:0000256|PIRNR:PIRNR003354}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004255, ECO:0000256|PIRNR:PIRNR003354}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004255}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000256|ARBA:ARBA00004347}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004347}; Cytoplasmic side {ECO:0000256|ARBA:ARBA00004347}.
Sequence: MLTNFESKSARVKGLSFHPKRPWILVSLHSGVIQLWDYRMHTLLEKFDEHDGPVRGVAFHQQMPLFVSGGDDYKIKVWNYKQRRCIFTLLAHLDYVRTVAFHHEYPWILSASDDQTIRIWNWQSRNCICVLTGHNHYVMCAQFHPTEDQIVSASLDQTVRVWDISGLRKKNVAPGPGGLDDHLKGHPGATDLFGQADAVVKHVLEGHDRGFNWASFHPTLPLIVSGADDRLVKLWRMNEYKAWEVDTCRGHYNNVSSVLFHPRQDLILSNGEDRSIRVWDMTKRQCLFTFRRDNERFWILTAHPTLNLFAAGHDGGMVVFKLERERPAYAVHGNILYYVKERFLRKLDFTTTKDTVVMQLRPGKSPVYSMSYNPALNAVLICTRTNNLENSTYDLCQIPKDTESQSESDSKRSSGITAIWVARNRFAVLDRNQQLVIKNFKNEVTKKLPTFCEEIFYAGTGMLLIRDPEFVTLYEVQRLVSVGSIKLAKCRYVVWSPDMSLVALLCKHSVTICDRRLQYLCTVQENCRVKSGAWDESGVFIYTTSNHIKYAITNGDHGIIRTLDLPIYLTRVKGNQVFCLDRECRTRVLHIDPTEYKFKLALIQRKYDEVLHMVRNARLVGQSIIAYLQQKGYPEVALHFVKDEKTRFGLALECGNIEIALEAAKALDDKDCWDRLGQSALLQGNHQVVEMCYQRTKNFDKLSFLYLITGNLEKLKKMNKIAEIRKDVSAQYQGALLLGDVKERVNILKNCGQLSLAYLTAATHGFDELTESLGESITSQGNSLPEVNPNAQLLQPPVPIQQLETNWPLLSVSKGFFEGAMVTRAGSSATARQALNINADAALLDEHNGGGDGWGADADLGLDEDGDDEMHDALSNDGDGGAGGEEGAGWDVGDDDLVVPEELASKIKASALDSNYYAAPNKGLSPAQQWANNSPLVLDHVKAGSFETAFRLLHDQLGVVNFQPFKTLFLQNYACSRTSYTANPNLQSLSGYPLRNYSETNIKLQRPAVGIKLNDLVARLQAGYQLTTSGKFSEAVEKFHSILISIPLLVVDTKLDAAEAQQLLRICAEYIVGLKMETVRKGMPKSTLEEQKRLCEMAAYFTHCKLQPVHQILTLRTALNMFFKLKNYKTAASFARRLLELAPRPDVAQQVRKILQAYEVNPVDEHQLQYEEFNPFTICGISWKPLYRGKPEVTCPFCSSSFDPQFKGNLCTVCEVSQIGKDSIGLRISNLQFR
InterPro domains: - IPR019775: WD40 repeat, conserved site (conserved_site) [150-164]
- IPR001680: WD40 repeat (repeat) [2-321]
- IPR020472: PAC1/LIS1-like, WD-40 repeat (repeat) [108-281]
- IPR016391: Coatomer subunit alpha (family) [1-1230]
- IPR047312: Coatomer subunit alpha, WD Associated Region (domain) [327-773]
- IPR010714: Coatomer, alpha subunit, C-terminal (domain) [814-1234]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [1-323]
- IPR056176: COPA/B, TPR domain (domain) [622-769]
- IPR050844: Coatomer complex subunit (family) [7-334]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [5-546]
- IPR006692: COPA/B, second beta-propeller domain (domain) [364-581]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0019953 (sexual reproduction), GO:0051641 (cellular localization), GO:0048856 (anatomical structure development), GO:0009653 (anatomical structure morphogenesis), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0051321 (meiotic cell cycle), GO:0022402 (cell cycle process), GO:0032879 (regulation of localization), GO:0007049 (cell cycle), GO:0051301 (cell division), GO:0071840 (cellular component organization or biogenesis), GO:1903046 (meiotic cell cycle process), GO:0032504 (multicellular organism reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0033036 (macromolecule localization), GO:0000902 (cell morphogenesis), GO:0007276 (gamete generation), GO:0000910 (cytokinesis), GO:0140013 (meiotic nuclear division), GO:0070727 (cellular macromolecule localization), GO:0016043 (cellular component organization), GO:0010883 (regulation of lipid storage), GO:0051668 (localization within membrane), GO:0033206 (meiotic cytokinesis), GO:0007140 (male meiotic nuclear division), GO:0007112 (male meiosis cytokinesis), GO:0061640 (cytoskeleton-dependent cytokinesis), GO:0008104 (protein localization), GO:0006996 (organelle organization), GO:0048232 (male gamete generation), GO:0072657 (protein localization to membrane), GO:0048285 (organelle fission), GO:1990778 (protein localization to cell periphery), GO:0000280 (nuclear division)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0030117 (membrane coat), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0048475 (coated membrane), GO:0005793 (endoplasmic reticulum-Golgi intermediate compartment), GO:0005794 (Golgi apparatus), GO:0043227 (membrane-bounded organelle), GO:0030126 (COPI vesicle coat), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0012506 (vesicle membrane), GO:0005798 (Golgi-associated vesicle), GO:0030120 (vesicle coat), GO:0030135 (coated vesicle), GO:0031982 (vesicle), GO:0030659 (cytoplasmic vesicle membrane), GO:0097708 (intracellular vesicle), GO:0030137 (COPI-coated vesicle), GO:0030662 (coated vesicle membrane), GO:0030660 (Golgi-associated vesicle membrane), GO:0030663 (COPI-coated vesicle membrane)