wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: RRM domain-containing protein (Q7JMB8)
Organism: Caenorhabditis elegans
Function: Not known
Sequence: MNASSAPQQQQQQQQPQQGQAPQQQQQGPPQHQYQQQRPFHGRVQNHMRGSGPFGNSNGYGRYTAPRGDQQHHDSTPLSSTNLYIRGLMPNTNDDLLREMCSKYGNIASTKAIMDKATNNCKGYGFVDFESPQAAAAAVDGLNTEGVQAQMAKLQQQEQDPTNLYIANLPLDFTEQMLETELNKFGMVISTRILRTPDNQSRGVGFARMDSKEKCEVIISALNGGRFDTMSKEGPALLIKQADTGRKSKHSMNNPEMLQRMQYPQVYQSYYGYHPAAVYQQHYDVNSLASQMGGMHVGGGNPQANGGGDMYGAHMYGQNAGGQGGQGVGQGGQGGNQQFYNPNNGRNKKYFQPMNPQ
InterPro domains: - IPR035979: RNA-binding domain superfamily (homologous_superfamily) [79-227]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [2-252]
- IPR000504: RNA recognition motif domain (domain) [81-244]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0048523 (negative regulation of cellular process), GO:0009892 (negative regulation of metabolic process), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0034248 (regulation of amide metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0051246 (regulation of protein metabolic process), GO:0051248 (negative regulation of protein metabolic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0010629 (negative regulation of gene expression), GO:0010468 (regulation of gene expression), GO:0034249 (negative regulation of amide metabolic process), GO:0017148 (negative regulation of translation), GO:2000112 (regulation of cellular macromolecule biosynthetic process), GO:0006417 (regulation of translation), GO:2000113 (negative regulation of cellular macromolecule biosynthetic process), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Globin c1 (Hemoglobin alpha, adult chain 3) (Q63910)
Organism: Rattus norvegicus (Rat)
Function: Not known
Sequence: MVLSEEDKNNIKKAWVKIGNHAAEIGAETIGRLFIVFPSSKTYFPHFNTSEGSDQVKAHGKKVADALTNAASHLDDLPGALSTLSDLHAHKLRVDPVNFKFLSHCLLVTLASHHPGDFTPAMHASLDKFFASVSTVLTSKYR
InterPro domains: - IPR002339: Hemoglobin, pi (family) [4-116]
- IPR012292: Globin/Protoglobin (homologous_superfamily) [2-142]
- IPR050056: Hemoglobin and related oxygen transporters (family) [1-142]
- IPR000971: Globin (domain) [2-142]
- IPR002338: Hemoglobin, alpha-type (family) [3-142]
- IPR009050: Globin-like superfamily (homologous_superfamily) [2-142]
Interaction partners: - Hemoglobin subunit beta-1
- Globin b1
- Epsilon 3 globin
- Haptoglobin
- Hemoglobin alpha, adult chain 2
- Globin a1
- Hemoglobin subunit beta like 1
- Hemoglobin subunit beta-2
- Epsilon 2 globin
- Alpha-hemoglobin-stabilizing protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0033218 (amide binding), GO:0005515 (protein binding), GO:0042277 (peptide binding), GO:0005102 (signaling receptor binding), GO:0001540 (amyloid-beta binding), GO:0001664 (G protein-coupled receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:1901700 (response to oxygen-containing compound), GO:0032355 (response to estradiol), GO:0033993 (response to lipid), GO:0014070 (response to organic cyclic compound)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction), GO:0045202 (synapse)
Protein: Protein bunched, class 2/F/G isoform (Protein shortsighted) (Q24523)
Organism: Drosophila melanogaster (Fruit fly)
Function: Probable transcription factor required for peripheral nervous system morphogenesis, eye development and oogenesis. May be required for the transmission of the dpp signal and for a morphogenetic movement of the medulla in the brain that reorients the second optic lobe relative to the first. Plays a role in determining proper dorsal cell fates leading to the formation of the dorsal appendages.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:7555710}. Nucleus {ECO:0000269|PubMed:7555710}.
Sequence: MFDRTVNAKFKPASSNAGPGNNPVRRNSMLTPSRGVTIGGTGGNIRKLTKVSSLTSNHHFAVCYPPSNIYQNSNNAGSNSALQRTTSESLRLNMMSRVAAGATPTTVSRASSNSSLATSTSTSLAPKSSSSSGGSNSTPQQQQQQLVSSNNSSSSSNNSFTKASSPNNNGARSVGGAATSAATGTTAAAGSHHHQPHHHHHHHHHHHQHHNHQQQQQQQTSLSQGHASLTVAGGSASAGGGGGGGSGSSSGTAAGGTNRKPKTTSSFEITSVTVGHPKLNAAGDTGDESADDLDESHTDDNSRITDLENETPSMSEDTFSKEEVYYANNALSTNAPVIPTSSQYGLVVVDPIAPSLGQTIQNVQVNVSDNIINVVSGAVTPGGTKKKDDIKETQHRSERFKVVKIESTEPFKRGRWMCMDYLDHSSVGNGGNNNEKTGSSTSEAHAATTDGGAAGVGAGSEAPAHKTTQSMILPPTQKLNENHLEANSTDANWNYAEQQQQQQQQQQQQQTIVGNALTKTLPVALRNVSRSSSVTRSPNATVEFLSPNLLAQQQQQQQQLFDSVNANAASSPNPAGDPNNMDYARTAAMQLHQTLQQLKQREDAMDVPPGAGGYANYQNGGDSAVGAASNNNSAAAATGESQLSTSYVEQQQQQQQPLSPAPLTPQAAPTFAAVAAGQSPNFQLEQQQQQQQATSQIDGIVPQPFNPQQQQQQTPQQSTAQQAAAAANATSAVTAPPPQQTSNTSNAAVTTGQGQTMPLLSHMTSYEQQQPNLGAAAAAAAAGGTAATSVAAPQAIPTLQLQSAPSTIADPQQLMVPQQQQQQQHQEEQQQQPQQQQQPLPPANIASASANNSNLNLTNTNVVATGEATTNALTLTDEQATAALAAAFATGAAAAATGATSAAAATQQQIQQLQQQPNAESETESFITASNPGGNRKRAFSNPHIGGPNDPSFMHRLNPQLYYYNKSQSGRSSFCVDESLWPTNNPNGAVSDTNLYMGSSTDEDYEEAIDQFSPTIYTTRSASRAIPIPNSAGSSPQHQMHHSQPRIAIGINQMEGGGPTRSTGAFSASPSIYAYPHSPFYASSPETSFGSAAMPGHPAASSRISFSYDPAFQRLQVPNASGDRRPRSPLECASVFAAVAAAATCGDAAGGAADTVISSASGTSAVAIDNKIEQAMDLVKSHLMIAVREEVEVLKERISELMDKINKLELENSILKSNIPQETLQQLQLQLQLAAPPATPAIQAAPAVQSVVAPAAAGQAVQQQAAGAVAVTGVATSPASAVVPTSIPNGSAENGSSAVESAAVSVEQQVQQVTSAAAAAASVVTANGPMS
InterPro domains: - IPR047862: TSC22/Bun, conserved site (conserved_site) [1176-1192]
- IPR000580: TSC22/Bun (family) [1176-1232]
Interaction partners: - Nuclear receptor-binding protein homolog
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0065007 (biological regulation), GO:0048523 (negative regulation of cellular process), GO:0050794 (regulation of cellular process), GO:0060548 (negative regulation of cell death), GO:0010941 (regulation of cell death), GO:1901214 (regulation of neuron death), GO:1901215 (negative regulation of neuron death)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Serine protease 27 (EC 3.4.21.-) (Marapsin) (Pancreasin) (Q8BJR6)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Secreted {ECO:0000250}.
Sequence: MRQPHIAALLLLPLLLRSGTEGARTLRACGHPKMFNRMVGGENALEGEWPWQVSIQRNGIHFCGGSLIAPTWVLTAAHCFSNTSDISIYQVLLGALKLQQPGPHALYVPVKQVKSNPQYQGMASSADVALVELQGPVTFTNYILPVCLPDPSVIFESGMNCWVTGWGSPSEQDRLPNPRVLQKLAVPIIDTPKCNLLYNKDVESDFQLKTIKDDMLCAGFAEGKKDACKGDSGGPLVCLVDQSWVQAGVISWGEGCARRNRPGVYIRVTSHHKWIHQIIPELQFQGRAGTQQQQKDSQGQQRLAGNSAPCLAAHAMVLALGALLLRIV
InterPro domains: - IPR001314: Peptidase S1A, chymotrypsin family (family) [64-237]
- IPR043504: Peptidase S1, PA clan, chymotrypsin-like fold (homologous_superfamily) [41-276]
- IPR018114: Serine proteases, trypsin family, histidine active site (active_site) [74-79]
- IPR033116: Serine proteases, trypsin family, serine active site (active_site) [226-237]
- IPR009003: Peptidase S1, PA clan (homologous_superfamily) [1-279]
- IPR001254: Serine proteases, trypsin domain (domain) [37-280]
Interaction partners: - Condensin-2 complex subunit G2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0016247 (channel regulator activity), GO:0099106 (ion channel regulator activity), GO:0017080 (sodium channel regulator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0051234 (establishment of localization), GO:0051050 (positive regulation of transport), GO:0032879 (regulation of localization), GO:0051049 (regulation of transport), GO:0043270 (positive regulation of monoatomic ion transport), GO:0006810 (transport), GO:0010765 (positive regulation of sodium ion transport), GO:0043269 (regulation of monoatomic ion transport), GO:0070633 (transepithelial transport), GO:0010959 (regulation of metal ion transport), GO:0002028 (regulation of sodium ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0030141 (secretory granule), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0001669 (acrosomal vesicle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)
Protein: Tropomyosin 1 (B7Z596)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDHERKLRETAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEGKILSSVFSLILMVEYQPGKTIFQFKGIHIDTLLCTCTFFLCVLWGFSLWLLNS
InterPro domains: - IPR000533: Tropomyosin (family) [7-224]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0001503 (ossification), GO:0030154 (cell differentiation), GO:0001649 (osteoblast differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015629 (actin cytoskeleton)
Protein: Spermatogenesis-associated protein 22 (Testis development protein NYD-SP20) (Q8NHS9)
Organism: Homo sapiens (Human)
Function: Meiosis-specific protein required for homologous recombination in meiosis I.
Subcellular location: Chromosome {ECO:0000250|UniProtKB:Q5SV06}. Note=Localizes on meiotic chromosome axes. Accumulates on resected DNA. Localization is dependent on MEIOB. {ECO:0000250|UniProtKB:Q5SV06}.
Sequence: MKRSLNENSARSTAGCLPVPLFNQKKRNRQPLTSNPLKDDSGISTPSDNYDFPPLPTDWAWEAVNPELAPVMKTVDTGQIPHSVSRPLRSQDSVFNSIQSNTGRSQGGWSYRDGNKNTSLKTWNKNDFKPQCKRTNLVANDGKNSCPVSSGAQQQKQLRIPEPPNLSRNKETELLRQTHSSKISGCTMRGLDKNSALQTLKPNFQQNQYKKQMLDDIPEDNTLKETSLYQLQFKEKASSLRIISAVIESMKYWREHAQKTVLLFEVLAVLDSAVTPGPYYSKTFLMRDGKNTLPCVFYEIDRELPRLIRGRVHRCVGNYDQKKNIFQCVSVRPASVSEQKTFQAFVKIADVEMQYYINVMNET
InterPro domains: - IPR033536: Spermatogenesis-associated protein 22 (family) [1-362]
Interaction partners: - Meiosis-specific with OB domain-containing protein
- Heat shock factor 2-binding protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0033554 (cellular response to stress), GO:0006259 (DNA metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0006974 (cellular response to DNA damage stimulus), GO:0006310 (DNA recombination), GO:0006281 (DNA repair), GO:0000725 (recombinational repair), GO:0006302 (double-strand break repair), GO:0000724 (double-strand break repair via homologous recombination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0016604 (nuclear body), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005694 (chromosome), GO:0005634 (nucleus)
Protein: Sodium-coupled monocarboxylate transporter 1 (Electrogenic sodium monocarboxylate cotransporter) (zSMCTe) (Sodium solute symporter family 5 member 8 protein) (Solute carrier family 5 member 8) (Q3ZMH1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane.
Subcellular location: Apical cell membrane {ECO:0000250|UniProtKB:Q8N695}; Multi-pass membrane protein {ECO:0000255}.
Sequence: MPGSGGPVATFSVWDYVVFAGLILVAAGIGLFQSFRGRKEASSDEFLLGGRQMTAVPVALSLTASFMSGITVIGTPAEAYLYGTPFWLFFISYAIMSTISAEIFVPLFYRLNITSTYEYLEMRYNKLIRVIGTSMYIIQTALYTGMVIFAPALALNQITGLDLWGVLVATGAVCIIYCTLGGLKAVIWTDVFQMIIMLGGFVAVIARGAVLQGGLGRVWNDSFYGGRLETFSFDPDPLRRHSFWTIVVGGSLMWASMYSINQSQVQRYISCRTMTHAKLSLYVNMVGLWVTVSLAMMSGLTMYSIYKDCDPFTNKDVGATDQLLPYLVMDILADFPGLPGLFVAAAYSGTLSTVSSSINALVAVTVEDFMKPAWPSLTERQLSWINMGMSVFYGAVCIGMAGVASMMGNILQAALSIFGMISGPLLGLYMLGMFFRCANSTGGLAGLASGLAITLWVGIGAQLYPPLPEKTLRLPLSVEGCVALNTSETTTMTPFSTVLQTTTPQPRPALADNWYSLSYLYFSPVGIVVTMIIALIVSAISGGCKQKKVRPELFISKSDLICFRCKKSDSEVSDLIETKPKDNQGLDSPVFYDNEIVLKEKDQQEKITKL
InterPro domains: - IPR041992: SMCT1, solute-binding domain (domain) [8-547]
- IPR051163: Sodium:Solute Symporter (SSF) (family) [9-563]
- IPR038377: Sodium/glucose symporter superfamily (homologous_superfamily) [40-561]
- IPR001734: Sodium/solute symporter (family) [12-464]
Interaction partners: - Neutral amino acid uniporter 4
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity), GO:0005342 (organic acid transmembrane transporter activity), GO:1901618 (organic hydroxy compound transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0046943 (carboxylic acid transmembrane transporter activity), GO:0008028 (monocarboxylic acid transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0071702 (organic substance transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Gametocyte-specific factor 1-like (Protein FAM112A) (Q9H1H1)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MEPEAFEICPYDPHHRIPLSRFQYHLASCRRKNPKKAKKMATCKYNACHVVPIKNLEEHEAVCVNRSAVEEEDTENPLKVSPPSSEQNDDTQQVSPCLPSPDIWNVDGANCQHVFVLKTFFPQKVVCENDTKESARETSPQKILRPGQ
InterPro domains: - IPR022776: TRM13/UPF0224 family, U11-48K-like CHHC zinc finger domain (domain) [6-67]
- IPR051591: UPF0224 (FAM112) RNA Processing (family) [2-92]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [6-34]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0000049 (tRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0008380 (RNA splicing), GO:0034470 (ncRNA processing), GO:0034660 (ncRNA metabolic process), GO:0000394 (RNA splicing, via endonucleolytic cleavage and ligation), GO:0006399 (tRNA metabolic process), GO:0008033 (tRNA processing), GO:0006388 (tRNA splicing, via endonucleolytic cleavage and ligation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Assembly factor cbp4 (Cytochrome b mRNA-processing protein 4) (Q9USV6)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Sequence: MNRVVKSIVYGVGIVGFGYMTMKLTTPSPERVVNSLPPDLRASYEMNKKDRSQAEGVLRMIEDAKRNPKNLV
InterPro domains: - IPR012420: Cbp4 (family) [3-54]
Interaction partners: - CBP3-like protein
- Cytochrome b-c1 complex subunit 9
- Cytochrome b-c1 complex subunit 8
- Cytochrome b-c1 complex subunit 7
- Cytochrome b
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044237 (cellular metabolic process), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0006091 (generation of precursor metabolites and energy), GO:0043933 (protein-containing complex organization), GO:0015980 (energy derivation by oxidation of organic compounds), GO:0006996 (organelle organization), GO:0022900 (electron transport chain), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly), GO:0007005 (mitochondrion organization), GO:0045333 (cellular respiration), GO:0022904 (respiratory electron transport chain), GO:0033108 (mitochondrial respiratory chain complex assembly), GO:0019646 (aerobic electron transport chain), GO:0009060 (aerobic respiration), GO:0017004 (cytochrome complex assembly), GO:0042773 (ATP synthesis coupled electron transport), GO:0017062 (respiratory chain complex III assembly), GO:0006119 (oxidative phosphorylation), GO:0034551 (mitochondrial respiratory chain complex III assembly), GO:0042775 (mitochondrial ATP synthesis coupled electron transport), GO:0006122 (mitochondrial electron transport, ubiquinol to cytochrome c)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)