Protein: NFAT nuclear factor, isoform G (M9PH25)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MLLKFTKTSGAGPSAVPLLTTAPATVTSSASMQATTTSYAARGTGMRMTMSTNSTMSARIHRKGFRIPSKRQPGKGLPGKLHTITRTGPGKMVPGKRIPQRPHPPPCDNSNDSGLGFDQHTELRSSAGAGGVTDPAANGGSGSNSGQRSSLLVNSALTNTVAAAAAAAAAAVASNTLQQHQQHHQQQQQQQQQQQQQQQQQQQQQQQQQHSPQQHLIRAIPVSRFISARNVTRVANKRQPTTPLNSVASSNDGQVQLEILSQPEQQHRARYQTEGSRGAVKDRSGNGFPIVRLTGYDKVAVLQVFIGTDIGRVAPHMFYQACKVAGKNSTQCNEKKVDGTMVIEIDFKPETDMTITCDCVGILKERNVDVEHRFPEHLAQKNKKKSTRCRMVFRTQLTRDDGTTETLQVCSNPIICTQPPGVPEICKKSLNSCPVDGGLELFIIGKNFLKDTHVVFQETYDSVNGDDPATEIAVRQQLIGGTAALWEQSVLPDKEYLHQTHLICTVPPYLHQNILKPVQVQVSIVSSGKKSEPHTFTYTAKGQYTTLAAASTLSNTIHAQAI
InterPro domains: - IPR002909: IPT domain (domain) [422-539]
- IPR008366: Nuclear factor of activated T cells (NFAT) (family) [235-543]
- IPR015646: Nuclear factor of activated T-cells 5, Rel homology domain, DNA-binding domain (domain) [255-418]
- IPR037059: Rel homology domain (RHD), DNA-binding domain superfamily (homologous_superfamily) [243-417]
- IPR032397: Rel homology dimerisation domain (domain) [424-541]
- IPR008967: p53-like transcription factor, DNA-binding domain superfamily (homologous_superfamily) [249-422]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [418-543]
- IPR014756: Immunoglobulin E-set (homologous_superfamily) [421-542]
- IPR011539: Rel homology domain, DNA-binding domain (domain) [239-421]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0009628 (response to abiotic stimulus), GO:0065008 (regulation of biological quality), GO:0051051 (negative regulation of transport), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0023051 (regulation of signaling), GO:0006950 (response to stress), GO:0048523 (negative regulation of cellular process), GO:1903530 (regulation of secretion by cell), GO:0051049 (regulation of transport), GO:0010646 (regulation of cell communication), GO:0006970 (response to osmotic stress), GO:0001505 (regulation of neurotransmitter levels), GO:0060627 (regulation of vesicle-mediated transport), GO:0099177 (regulation of trans-synaptic signaling), GO:0051048 (negative regulation of secretion), GO:1903531 (negative regulation of secretion by cell), GO:0051588 (regulation of neurotransmitter transport), GO:0046928 (regulation of neurotransmitter secretion), GO:0050804 (modulation of chemical synaptic transmission), GO:0017157 (regulation of exocytosis), GO:0009651 (response to salt stress), GO:0051046 (regulation of secretion), GO:0045920 (negative regulation of exocytosis), GO:1903306 (negative regulation of regulated secretory pathway), GO:1903305 (regulation of regulated secretory pathway), GO:2000300 (regulation of synaptic vesicle exocytosis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)