Protein: Acryloyl-CoA reductase electron transfer subunit beta (Electron transfer flavoprotein large subunit) (ETFLS) (Electron transfer flavoprotein subunit beta) (Beta-ETF) (G3KIM6)
Organism: Anaerotignum propionicum (Clostridium propionicum)
Function: Part of the ETF-acryloyl-CoA reductase complex involved in the pathway of L-alanine fermentation. The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for acryloyl-CoA reductase.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:12603323}.
Sequence: MAFNSADINSFRDIWVFCEQREGKLINTDFELISEGRKLADERGSKLVGILLGHEVEEIAKELGGYGADKVIVCDHPELKFYTTDAYAKVLCDVVMEEKPEVILIGATNIGRDLGPRCAARLHTGLTADCTHLDIDMNKYVDFLSTSSTLDISSMTFPMEDTNLKMTRPAFGGHLMATIICPRFRPCMSTVRPGVMKKAEFSQEMAQACQVVTRHVNLSDEDLKTKVINIVKETKKIVDLIGAEIIVSVGRGISKDVQGGIALAEKLADAFGNGVVGGSRAVIDSGWLPADHQVGQTGKTVHPKVYVALGISGAIQHKAGMQDSELIIAVNKDETAPIFDCADYGITGDLFKIVPMMIDAIKEGKNA
InterPro domains: - IPR014731: Electron transfer flavoprotein, alpha subunit, C-terminal (domain) [240-322]
- IPR029035: DHS-like NAD/FAD-binding domain superfamily (homologous_superfamily) [238-360]
- IPR033947: Electron transfer flavoprotein, alpha subunit, N-terminal (domain) [14-208]
- IPR050041: Acryloyl-CoA reductase electron transfer subunit beta (family) [5-363]
- IPR001308: Electron transfer flavoprotein alpha subunit/FixB (family) [7-366]
- IPR014729: Rossmann-like alpha/beta/alpha sandwich fold (homologous_superfamily) [10-235]
- IPR014730: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal (domain) [14-227]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0016491 (oxidoreductase activity), GO:1901265 (nucleoside phosphate binding), GO:0016627 (oxidoreductase activity, acting on the CH-CH group of donors), GO:0043168 (anion binding), GO:0000166 (nucleotide binding), GO:0016628 (oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor), GO:0070402 (NADPH binding), GO:0017076 (purine nucleotide binding), GO:0030554 (adenyl nucleotide binding), GO:0050661 (NADP binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006575 (cellular modified amino acid metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901575 (organic substance catabolic process), GO:0044248 (cellular catabolic process), GO:0006577 (amino-acid betaine metabolic process), GO:0044270 (cellular nitrogen compound catabolic process), GO:0042219 (cellular modified amino acid catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0006579 (amino-acid betaine catabolic process), GO:0009437 (carnitine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)