Protein: thioredoxin-dependent peroxiredoxin (EC 1.11.1.24) (Q9VUM4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MRMLNINQVAPNFTTNAVVSGGYRNFALTDLRGRYVLLVFYPADFSYVCPTELQAFSDRAPEFRNVGCEVLACSTDSHFVHCAWMNTPRKNGGLGELDIPLLADKNMKIARDYGVLDEDTGLALRALFIIDREGRIRQITVNDMGVGRSVDEALRLVQAFQFSDEFGEVCPVNWRPGAKTMKADATGKEEYFKHAI
InterPro domains: - IPR024706: Peroxiredoxin, AhpC-type (family) [1-196]
- IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [3-193]
- IPR013766: Thioredoxin domain (domain) [4-162]
- IPR019479: Peroxiredoxin, C-terminal (domain) [159-193]
- IPR000866: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant (domain) [6-138]
- IPR050217: Thiol-specific antioxidant peroxiredoxin (family) [4-194]
Interaction partners: - Peroxiredoxin 2
- Sulfiredoxin
- Peroxiredoxin-5
- AT22380p
- Thioredoxin-2
- Thioredoxin-1
- Proteasome subunit beta
- Thioredoxin-T
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016209 (antioxidant activity), GO:0004601 (peroxidase activity), GO:0005515 (protein binding), GO:0016491 (oxidoreductase activity), GO:0016684 (oxidoreductase activity, acting on peroxide as acceptor), GO:0051920 (peroxiredoxin activity), GO:0140824 (thioredoxin-dependent peroxiredoxin activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0022414 (reproductive process), GO:0042592 (homeostatic process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0019725 (cellular homeostasis), GO:0048870 (cell motility), GO:0008340 (determination of adult lifespan), GO:0044237 (cellular metabolic process), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0007155 (cell adhesion), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0009056 (catabolic process), GO:0009991 (response to extracellular stimulus), GO:0007276 (gamete generation), GO:0007281 (germ cell development), GO:0042594 (response to starvation), GO:0045454 (cell redox homeostasis), GO:0006979 (response to oxidative stress), GO:0048468 (cell development), GO:0072593 (reactive oxygen species metabolic process), GO:0030154 (cell differentiation), GO:0044248 (cellular catabolic process), GO:0042743 (hydrogen peroxide metabolic process), GO:0008354 (germ cell migration), GO:1901575 (organic substance catabolic process), GO:0016477 (cell migration), GO:0042744 (hydrogen peroxide catabolic process), GO:0031667 (response to nutrient levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)