Protein: Histone deacetylase-like protein HDO2 (Q8T6T5)
Organism: Trypanosoma brucei
Function: Not known
Sequence: MVVEPPASIPPVAVIVSTDVDAPASLPALQHNKLIIDMVRHYGCTPFPRKEVGGEAAFCNDIFEWVDRNLPSVDVEDMTAFHDESYVRYLSLREVASGDDEHVLSFSGCSNIRGTPSKRFASRRCSAPLPPFVLFPQNGDKRFNLVGDSAPFSGMWRFTQAVVSGTLAATRLLAQPSRFAAIHWMGGKHNAKRASAGGSCLVNDVVLAVLELRKLLPANRNVVLAVDPDAHHGDGAQEAFLSDPRVVTLSLHAYGIGIFPGTGSLEEIGSGLGRGYTMNIPLPVGATDALVVPMAQRGIYSAFRRAGVELGAVVVVCGSNSLSGDPYGLLNLTIGGYQRILRTLLTEAASHSAKVLMLGGSCNVEVAAARLAGVLTRDVFSCATALRNGDTSYFSWSPDLSTEKGVEVPEDCEYFTMYGPSFLMHSLPLAVVDEVHHFPPDSVLFSRMRQIAAKGERNSQMRDRAARKTVIEDDEEEESESEEEDTDEEEETESEGDENTSSQEGTDEEVVIDEDEETNGEGDEDTSSQEGNDEEEDTDETVLTDHVREGFPCLKERICGSLSEGQ
InterPro domains: - IPR023696: Ureohydrolase domain superfamily (homologous_superfamily) [34-433]
- IPR037138: Histone deacetylase domain superfamily (homologous_superfamily) [33-443]
- IPR023801: Histone deacetylase domain (domain) [70-360]
- IPR000286: Histone deacetylase HDAC (family) [186-320]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0033558 (protein lysine deacetylase activity), GO:0019213 (deacetylase activity), GO:0004407 (histone deacetylase activity), GO:0016811 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:1901657 (glycosyl compound metabolic process), GO:0072521 (purine-containing compound metabolic process), GO:0009116 (nucleoside metabolic process), GO:0009119 (ribonucleoside metabolic process), GO:0042278 (purine nucleoside metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0043233 (organelle lumen), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0099568 (cytoplasmic region), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005929 (cilium), GO:0032838 (plasma membrane bounded cell projection cytoplasm), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0097014 (ciliary plasm), GO:0005634 (nucleus)