wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Dehydration-induced protein RD22-like protein (Q8VWQ1)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Function: Not known
Sequence: MKVLSPILACLALAVVVSHAALSPEQYWSYKLPNTPMPKAVKEILHPELMEEKSTSVNVGGGGVNVNTGKGKPGGDTHVNVGGKGVGVNTGKPGGGTHVNVGDPFNYLYAASETQIHEDPNVALFFLEKDMHPGATMSLHFTENTEKSAFLPYQTAQKIPFSSDKLPEIFNKFSVKPGSLKAEMMKNTIKECEQPAIEGEEKYCATSLESMIDYSISKLGKVDQAVSTEVEKQTPMQKYTIAAGVQKMTDDKAVVCHKQNYAYAVFYCHKSETTRAYMVPLEGADGTKAKAVAVCHTDTSAWNPKHLAFQVLKVEPGTIPVCHFLPRDHIVWVPK
InterPro domains: - IPR044816: BURP domain-containing protein (family) [17-334]
- IPR004873: BURP domain (domain) [123-335]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016787 (hydrolase activity), GO:0140098 (catalytic activity, acting on RNA), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0004518 (nuclease activity), GO:0004540 (ribonuclease activity)
Biological Process (BP): GO:0008150 (biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048589 (developmental growth), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0016049 (cell growth), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0009791 (post-embryonic development), GO:0000902 (cell morphogenesis), GO:0048316 (seed development), GO:0090378 (seed trichome elongation), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0060560 (developmental growth involved in morphogenesis), GO:0030154 (cell differentiation), GO:0009826 (unidimensional cell growth), GO:0048731 (system development), GO:0090376 (seed trichome differentiation), GO:0048608 (reproductive structure development), GO:0061458 (reproductive system development), GO:0000904 (cell morphogenesis involved in differentiation), GO:0090558 (plant epidermis development), GO:0010026 (trichome differentiation), GO:0010154 (fruit development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0005794 (Golgi apparatus), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0098791 (Golgi apparatus subcompartment), GO:0065010 (extracellular membrane-bounded organelle), GO:0031985 (Golgi cisterna), GO:0043231 (intracellular membrane-bounded organelle), GO:0005795 (Golgi stack), GO:0031982 (vesicle), GO:0005802 (trans-Golgi network), GO:0000138 (Golgi trans cisterna), GO:0097708 (intracellular vesicle)
Protein: Possible transcriptional regulatory protein (P95217)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Not known
Sequence: MAQAHSAPLTGYRIAVTSARRAEELCALLRRQGAEVCSAPAIKMIALPDDDELQNNTEALIADPPDILVAHTGIGFRGWLAAAEGWGLANELLESLSSARIISRGPKATGALRAAGLREEWSPDSESSHEVLEYLLESGVSRTRIAVQLHGAADSWDPFPEFLGGLRFAGAQVVPIRVYRWKPAPLGGVFDHLVTGIARRQFDAVTFTSAPAAAAVLERSRELDIEDQLLAALRTDVHAMCVGPVTSRPLIRKGVPTSAPERMRLGALARHIAEELPLLGSCTFKAAGHVIEIRGTSVLVDDSVKPLSPSGMAILRALVHRPGGVVSRGDLLRVLPGDGSDTHAVDTAVLRLRTALGDKNIVATVVKRGYRLAVDSRHDDV
InterPro domains: - IPR036108: Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily (homologous_superfamily) [11-276]
- IPR039793: Uroporphyrinogen-III synthase (family) [1-283]
- IPR003754: Tetrapyrrole biosynthesis, uroporphyrinogen III synthase (domain) [14-272]
- IPR001867: OmpR/PhoB-type DNA-binding domain (domain) [281-374]
- IPR016032: Signal transduction response regulator, C-terminal effector (homologous_superfamily) [286-372]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [281-380]
Interaction partners: - uroporphyrinogen-III C-methyltransferase
- Porphobilinogen deaminase
- Sirohydrochlorin chelatase
- Probable uroporphyrin-III C-methyltransferase HemD
- Uroporphyrinogen decarboxylase
- Probable integral membrane nitrite extrusion protein NarK3
- assimilatory sulfite reductase
- Nitrate/nitrite transporter
- Tetracyclin repressor-like C-terminal domain-containing protein
- Probable conserved membrane protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016835 (carbon-oxygen lyase activity), GO:0016836 (hydro-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006520 (amino acid metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044283 (small molecule biosynthetic process), GO:0006082 (organic acid metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0009072 (aromatic amino acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0016053 (organic acid biosynthetic process), GO:0019438 (aromatic compound biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0009073 (aromatic amino acid family biosynthetic process), GO:0046394 (carboxylic acid biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: ATP synthase, putative (EC 3.6.3.14) (Q383Y7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MSEARQIQSMIDFIEREAQEKADELNSAAQEEYDVEKMRLVEAEKVKVRANNEQKLKQVDVGRRVARANFSKAQRLRIMEAQSNIVEQLKENIKTKLMAFVKNTDSYKKLLVSILHEALSAVRTDAIVYTCKNDEPIVTGMLSELEQWYLKTVGTRVSIRMGKEYLNAEEALGGVVVKSHDGHIVCNWTLSSRMRNCVNDQLPTIRYYLFNPESSI
InterPro domains: - IPR038495: V-type ATPase subunit E, C-terminal domain superfamily (homologous_superfamily) [88-215]
- IPR002842: V-type ATPase subunit E (family) [4-211]
Interaction partners: - Vacuolar proton pump subunit B
- Uncharacterized protein
- V-type proton ATPase subunit
- V-type proton ATPase subunit F
- V-type ATPase, C subunit, putative
- 
- V-type proton ATPase subunit C
- V-type proton ATPase subunit H
- H
- Vacuolar ATP synthase subunit D, putative
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0140657 (ATP-dependent activity), GO:0042626 (ATPase-coupled transmembrane transporter activity), GO:0022857 (transmembrane transporter activity), GO:0005515 (protein binding), GO:0042625 (ATPase-coupled ion transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0019829 (ATPase-coupled monoatomic cation transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0015399 (primary active transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0022853 (active monoatomic ion transmembrane transporter activity), GO:0044769 (ATPase activity, coupled to transmembrane movement of ions, rotational mechanism), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0046961 (proton-transporting ATPase activity, rotational mechanism), GO:0015078 (proton transmembrane transporter activity), GO:0009678 (pyrophosphate hydrolysis-driven proton transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0098660 (inorganic ion transmembrane transport), GO:0006810 (transport), GO:0034220 (monoatomic ion transmembrane transport), GO:0098655 (monoatomic cation transmembrane transport), GO:0006811 (monoatomic ion transport), GO:0098662 (inorganic cation transmembrane transport), GO:0006812 (monoatomic cation transport), GO:1902600 (proton transmembrane transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: NADH-ubiquinone oxidoreductase chain 1 (EC 7.1.1.2) (Q2F9A3)
Organism: Oryza sativa subsp. indica (Rice)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|RuleBase:RU000471}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU000471}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: TYIAVPAEILCLILPLLLGVAFLVLAERKVMAFVQRRKGPDVVGSFGLLQPLADGLKLILKEPISPSSANFSLFRMAPVATFMLSLVAWAVVPFDYGMVLSDPNIGLLYLFAISSLGVYGIIIAGWSSNSKYAFLGALRSAAQMVPYEVSIGLILITVLICVGPCNSSEIVMAQKQIWSGIPLFPVLVMFFIPCLAETNRAPSDLPEAEAESVAGYNVEYASMGSALFFLGEYANMILMRGLCTSLFPGGWPPILDLPISKKIPCSIWFSIKVLLFLFLYIWVRAAFPRYRYDQLMGLGRKVFLPLSLARVVPVSGVSVTFRWLP
InterPro domains: - IPR001694: NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H (family) [1-323]
- IPR018086: NADH:ubiquinone oxidoreductase, subunit 1, conserved site (conserved_site) [47-62]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016651 (oxidoreductase activity, acting on NAD(P)H), GO:0003954 (NADH dehydrogenase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0006970 (response to osmotic stress), GO:0001101 (response to acid chemical), GO:0009266 (response to temperature stimulus), GO:1901700 (response to oxygen-containing compound), GO:0009414 (response to water deprivation), GO:0010035 (response to inorganic substance), GO:0009415 (response to water), GO:0009409 (response to cold), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:1902074 (response to salt), GO:0097305 (response to alcohol), GO:0009651 (response to salt stress), GO:0009737 (response to abscisic acid), GO:0033993 (response to lipid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Ectodermal-neural cortex 1 (Q2V9T0)
Organism: Rattus norvegicus (Rat)
Function: Not known
Sequence: MSVRVHENRKSRASSGSINIYLFHKSSYADSVLTHLNLLRQQRLFTDVLLHAGNRTFPCHRAVLAACSRYFEAMFSGGLKESQDSEVNFDNSIHPEVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDACAEFLEKNLHPTNCLGMLLLSDAHQCTKLYELSWRMCLSNFQTIRKNEDFLQLPQDMVVQLLSSEELETEDERLVYESAMNWISYDLKKRYCYLPELLQTVRLALLPAIYLMENVAMEELITKQRKSKEIVEEAIRCKLKILQNDGVVTSLCARPRKTGHALFLLGGQTFMCDKLYLVDQKAKEIIPKADIPSPRKEFSACAIGCKVYITGGRGSENGVSKDVWVYDTLHEEWSKAAPMLVARFGHGSAELKHCLYVVGGHTAATGCLPASPSVSLKQVEQYDPTTNKWTMVAPLREGVSNAAVVSAKLKLFAFGGTSVSHDKLPKVQCYDQCENRWTVPATCPQPWRYTAAAVLGNQIFIMGGDTEFSACSAYKFNSETYQWTKVGDVTAKRMSCHAVASGNKLYVVGGYFGIQRCKTLDCYDPTLDVWNSITTVPYSLIPTAFVSTWKHLPS
InterPro domains: - IPR011705: BTB/Kelch-associated (domain) [149-251]
- IPR030562: Ectoderm-neural cortex protein 1, BTB/POZ domain (domain) [6-152]
- IPR006652: Kelch repeat type 1 (repeat) [296-585]
- IPR000210: BTB/POZ domain (domain) [36-144]
- IPR011333: SKP1/BTB/POZ domain superfamily (homologous_superfamily) [17-145]
- IPR015915: Kelch-type beta-propeller (homologous_superfamily) [284-586]
- IPR017096: BTB-kelch protein (family) [1-589]
- IPR047097: Ectoderm-neural cortex protein 1, BACK domain (domain) [145-242]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0051130 (positive regulation of cellular component organization), GO:0031344 (regulation of cell projection organization), GO:0031346 (positive regulation of cell projection organization), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0010976 (positive regulation of neuron projection development), GO:0010975 (regulation of neuron projection development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016363 (nuclear matrix), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:0044297 (cell body), GO:0036477 (somatodendritic compartment), GO:0034399 (nuclear periphery), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043025 (neuronal cell body), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005694 (chromosome), GO:0005634 (nucleus)
Protein: Tuberoinfundibular peptide of 39 residues (TIP39) (Parathyroid hormone 2) (Q8QGA2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Plays a role as a potent and selective agonist of pth2r resulting in adenyl cyclase activation and intracellular calcium level elevation.
Subcellular location: Secreted {ECO:0000305|PubMed:15297442}.
Sequence: MALSLPPRPALLFLVLMSVTLMASAFPQPQLRPLQSNLPAIGQEDSKGEQWEVVYPSISLRDWSIQMLTAPDFGAAKTGREQLVADDWLPLSQSQMEEELVKGWTGDWPSRVGHQQKRNIVVADDAAFREKSKLLTAMERQKWLNSYMQKLLVVNSK
InterPro domains: - IPR029396: Tuberoinfundibular peptide of 39 residues (family) [7-157]
Interaction partners: - Parathyroid hormone 2 receptor
- Parathyroid hormone 1 receptor b
- Parathyroid hormone 2 receptor
- Parathyroid hormone/parathyroid hormone-related peptide receptor
- Parathyroid hormone
- Parathyroid hormone 1a.
- Parathyroid hormone-like hormone
- Parathyroid hormone-like hormone b
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0001664 (G protein-coupled receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0043010 (camera-type eye development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed] (P60706)
Organism: Gallus gallus (Chicken)
Function: Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P60710}. Nucleus {ECO:0000250|UniProtKB:O93400}.
Sequence: MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
InterPro domains: - IPR020902: Actin/actin-like conserved site (conserved_site) [104-116]
- IPR043129: ATPase, nucleotide binding domain (homologous_superfamily) [3-375]
- IPR004000: Actin family (family) [3-375]
- IPR004001: Actin, conserved site (conserved_site) [53-364]
Interaction partners: - Profilin
- Cofilin-2
- Vinculin
- Profilin
- Profilin
- Ezrin
- Hematopoietic lineage cell-specific protein
- Talin-1
- Filamin B
- Uncharacterized protein.
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0009893 (positive regulation of metabolic process), GO:0048856 (anatomical structure development), GO:0009653 (anatomical structure morphogenesis), GO:0090130 (tissue migration), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0009887 (animal organ morphogenesis), GO:0048729 (tissue morphogenesis), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0009888 (tissue development), GO:0048513 (animal organ development), GO:0010628 (positive regulation of gene expression), GO:0072132 (mesenchyme morphogenesis), GO:0060485 (mesenchyme development), GO:0010468 (regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0099512 (supramolecular fiber), GO:0032982 (myosin filament)
Protein: Secreted protein P60-related protein (P71594)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Not known
Sequence: MNYSEVELLSRAHQLFAGDSRRPGLDAGTTPYGDLLSRAADLNVGAGQRRYQLAVDHSRAALLSAARTDAAAGAVITGAQRDRAWARRSTGTVLDEARSDTTVTAVMPIAQREAIRRRVARLRAQRAHVLTARRRARRHLAALRALRYRVAHGPGVALAKLRLPSPSGRAGIAVHAALSRLGRPYVWGATGPNQFDCSGLVQWAYAQAGVHLDRTTYQQINEGIPVPRSQVRPGDLVFPHPGHVQLAIGNNLVVEAPHAGASVRVSSLGNNVQIRRPLSGR
InterPro domains: - IPR051794: Peptidoglycan Endopeptidase C40 (family) [112-276]
- IPR000064: Endopeptidase, NLPC/P60 domain (domain) [167-281]
- IPR038765: Papain-like cysteine peptidase superfamily (homologous_superfamily) [163-272]
Interaction partners: - Uncharacterized HTH-type transcriptional regulator Rv0023
- Possible penicillin-binding lipoprotein
- Uncharacterized protein Rv0025
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0017171 (serine hydrolase activity), GO:0008233 (peptidase activity), GO:0008236 (serine-type peptidase activity), GO:0008238 (exopeptidase activity), GO:0070008 (serine-type exopeptidase activity), GO:0004180 (carboxypeptidase activity), GO:0004185 (serine-type carboxypeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response), GO:0042783 (evasion of host immune response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005618 (cell wall), GO:0009274 (peptidoglycan-based cell wall)
Protein: Cutinase CUT1 (EC 3.1.1.74) (CcCUT1) (B9U443)
Organism: Coprinopsis cinerea (Inky cap fungus) (Hormographiella aspergillata)
Function: Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle. Also degrades suberin, a specialized macromolecule found in the cell wall of various plant tissues.
Sequence: MKFTTLATLALGAVSALAAPVTELESRQLFCRDVYVFFARGTGEVGTLGTVVGPGLSAAVKLAVRDSVEFEGIDYPALVSGYLAGGDRGGARTMANKVSQTASRCPNAKIFISGYSQGAQVTHLAARQLSAADQARVTGVVTFGDPYRDDALPGGLQSRRKTYCNVGDLICAGLPTLLAPHFTYGSDTPDAARWIAARV
InterPro domains: - IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [1-199]
- IPR000675: Cutinase/acetylxylan esterase (family) [31-199]
- IPR011150: Cutinase, monofunctional (family) [28-198]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0052689 (carboxylic ester hydrolase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009056 (catabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901575 (organic substance catabolic process), GO:0006629 (lipid metabolic process), GO:0016042 (lipid catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)