wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Histone H1 (P54671)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
Subcellular location: Nucleus. Chromosome.
Sequence: MGPKAPTTPTKKAAATKSKPKPNHPTYQVMISTAIAHYKDRTGSSQPAIIKYIEANYNVAPDTFKTQLKLALKRLVAKGTLTMVKASYKLSEEGKKEHQATLGPVAKKPKAKTTATSTETTAAPPATPTKKAAPKKPAAKAASTSTKTAAAKKNSAKVTKAVSKKPAAKKAPSKKVAAKK
InterPro domains: - IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [20-99]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [18-101]
- IPR005818: Linker histone H1/H5, domain H15 (domain) [21-97]
- IPR005819: Linker histone H1/H5 (family) [10-180]
Interaction partners: - Histone H4
- Histone H2B.v3
- Cyclin-dependent kinase 5 homolog
- Histone H2A.z
- Histone H3.3 type a
- Histone H3.3 type c
- Cyclin-dependent kinase 1
- Putative cyclin-dependent serine/threonine-protein kinase DDB_G0272797/DDB_G0274007
- Probable cyclin-dependent serine/threonine-protein kinase DDB_G0292550
- Histone H3.3 type b
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003690 (double-stranded DNA binding), GO:0000217 (DNA secondary structure binding), GO:0003680 (minor groove of adenine-thymine-rich DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0051276 (chromosome organization), GO:0030261 (chromosome condensation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome)
Protein: Cutinase pbc1 (EC 3.1.1.74) (Cutin hydrolase) (Q9Y7G8)
Organism: Pyrenopeziza brassicae
Function: Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants (Probable). Degrades cutin, a macromolecule that forms the structure of the plant cuticle (Probable). Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of fungal infection (Probable).
Subcellular location: Secreted {ECO:0000250|UniProtKB:P11373}.
Sequence: MKVTALGNTLTGFGQALATTLGVDTTSSSPNCAEMMVVFARGTSEPGNVGLFSGPTFFDALEVMMGAGAVSVQGVEYGASIEGFLQGGDPAGSAAMAGIVEGTVQNCPNAKIVMSGYSQGGQLVHNAAAMLPAATMAKISSLVIFGDPNDGKPIANADPSKVMVVCHPGHNICDGRDLVLVEHLTYSRDAVEAATFAAARAKA
InterPro domains: - IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [1-202]
- IPR000675: Cutinase/acetylxylan esterase (family) [30-201]
- IPR043580: Cutinase, serine active site (conserved_site) [108-120]
- IPR011150: Cutinase, monofunctional (family) [26-202]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0052689 (carboxylic ester hydrolase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0006629 (lipid metabolic process), GO:1901575 (organic substance catabolic process), GO:0044248 (cellular catabolic process), GO:0006638 (neutral lipid metabolic process), GO:0046486 (glycerolipid metabolic process), GO:0044242 (cellular lipid catabolic process), GO:0016042 (lipid catabolic process), GO:0046461 (neutral lipid catabolic process), GO:0006639 (acylglycerol metabolic process), GO:0046503 (glycerolipid catabolic process), GO:0046464 (acylglycerol catabolic process), GO:0006641 (triglyceride metabolic process), GO:0019433 (triglyceride catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Collagen alpha-1(XXV) chain (CLAC-P) [Cleaved into: Collagen-like Alzheimer amyloid plaque component (CLAC)] (Q99MQ5)
Organism: Mus musculus (Mouse)
Function: Inhibits fibrillization of amyloid-beta peptide during the elongation phase. Has also been shown to assemble amyloid fibrils into protease-resistant aggregates. Binds heparin (By similarity).
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. Note=After proteolytic cleavage, CLAC is secreted. {ECO:0000250}.
Sequence: MLVKKLAGKGGGRESGSEDPRPLGQRCAGTMPSCTALATLLSVVAVAFCFYLGVKTNDLQARIAALESAKGTPSFHPLSDTVDELKAMVQEKVERLLAQKSYEHMAKIRTAREAPLECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPGTPGMDGQKGEPGSPGAAGQSGLPGPKGEPGKEGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGDRGEAGPPGRGERGDPGAPGPKGKQGESGARGPKGSKGDRGDKGDSGALGPRGPPGQKGDPGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGVDGEQGLKGSKGDMGDPGVPGEKGGLGLPGLPGANGVKGEKGDTGLPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGASGLDGKPGSRGADGPIGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKGFRGVKGEKGEPGQPGLDGLDAPCQLGPDGLPMPGCWQK
InterPro domains: - IPR050938: Collagen and Collagen-like Structural Proteins (family) [49-666]
- IPR008160: Collagen triple helix repeat (repeat) [122-643]
Interaction partners: - Collagen alpha-1
- Furin
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0001503 (ossification), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0001763 (morphogenesis of a branching structure), GO:0009887 (animal organ morphogenesis), GO:0036075 (replacement ossification), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0060349 (bone morphogenesis), GO:0048705 (skeletal system morphogenesis), GO:0060348 (bone development), GO:0001501 (skeletal system development), GO:0001958 (endochondral ossification), GO:0060350 (endochondral bone morphogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Protein LF2 (P0C725)
Organism: Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4)
Function: Prevents the establishment of cellular antiviral state by blocking the cellular IRF7-mediated innate immunity. May also inhibit viral replication by modulating BRLF1 activity.
Sequence: MAEAYPGGAHAALASRRSSFRNSLRRLRPTEKPDTSFMRGVWKYEIFPSYVRVTNKQVLQLDAQCQELPPCPSVGQILSFKLPSFSFNTTTYGSRYFTVAFLFFGAEDNEVFLKPFFVMHSDQDIVLSVLNPRSLFIEKGKFTWYIVPIRLVKNPYLYLQILPGQSDIQLTRSCTQSGDKLNTSEPQIFLSGSPVTSQDECLPYLLAQHTPPFLKSYARIHTFPGKVCPVNAIRRGKGYVRVSVDTPDLKREGPLNVKVGMTLLDDVIIAFRYNPYPKSHWRWDGESTDIRYFGSPVIIPPNFITELEYNNTYEAPLSSKITAVVVSHSSNPVFYVYPQEWKPGQTLKLTVRNISNNPITIVTGQSMAQAFFIYAGDPSISTIMRRYIQRQGCALTLPGNIVVESSSLPTFERINKTFNGNIVASEGTL
InterPro domains: - IPR006882: Herpesvirus Orf11 (family) [37-401]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0016032 (viral process), GO:0044068 (modulation by symbiont of host cellular process), GO:0050794 (regulation of cellular process), GO:0035821 (modulation of process of another organism), GO:0019048 (modulation by virus of host process), GO:0044403 (biological process involved in symbiotic interaction), GO:0048522 (positive regulation of cellular process), GO:0051701 (biological process involved in interaction with host), GO:0031341 (regulation of cell killing), GO:0052040 (modulation by symbiont of host programmed cell death), GO:0060548 (negative regulation of cell death), GO:0010941 (regulation of cell death), GO:0044003 (modulation by symbiont of host process), GO:0031343 (positive regulation of cell killing), GO:0075136 (response to host), GO:0051709 (regulation of killing of cells of another organism), GO:0019054 (modulation by virus of host cellular process), GO:0052150 (modulation by symbiont of host apoptotic process), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:0052041 (suppression by symbiont of host programmed cell death), GO:0052150 (modulation by symbiont of host apoptotic process), GO:0052150 (modulation by symbiont of host apoptotic process), GO:0042981 (regulation of apoptotic process), GO:0043066 (negative regulation of apoptotic process), GO:0019050 (suppression by virus of host apoptotic process), GO:0033668 (suppression by symbiont of host apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0033643 (host cell part), GO:0043657 (host cell), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0033647 (host intracellular organelle), GO:0030430 (host cell cytoplasm), GO:0033648 (host intracellular membrane-bounded organelle), GO:0042025 (host cell nucleus)
Protein: CCAAT-binding factor domain-containing protein (Q38AX4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MAAMQRYLMNTSYLSSQLKELHSLHNRTVSDYGELVENLTKECSILCDVIPNYKISATIEEEDGGQTGRKQKEVYQVQKLEHEVLVQYEHFLQLLRRLQRKPHPEQQALGSRLCARLVPRASEFNHADKLLSLAVTFANAKSTRVARPALTALAELLDGQMVSDATECIVSALLDIVRKQHYAMNPKLLNLLLHIRVAMVDMHRRDLTEEVAKNKRLKKEDKELARQLQKSKARRDRAEIVVKQSRILHRVFVIYLRVLEASKSCSQQHQTRILAPALEGLVKFAPLVNVELHQQLITALKDLVNDEATSVTTKLHALVSVASLAQRDATTTASDWRVDLSYFHEVLFRCLPEALTLPKCVESNKGTTGEGGDGDDDGDEVASQGSTSSAGSLSSQAFSITESMAQEKFVHSNASREWTFRVGLVLRAMDLLVLTQKHLPVPRVTAFVRRIMQAIPSCPPHIGLSLLALNHRLMLRYPAVSGIVIGGSDNFIAGRGVYTPGATQIASSNADCSFTWELSLLAKSFHPTMRNVAEVFCKHFYKVSKLTHGQAPVVTKQLDALGPYELLESHDPSSGEIRPPPPLPETMKRRKSGKLTAGVKRAHNDEASDPAGE
InterPro domains: - IPR016024: Armadillo-type fold (homologous_superfamily) [90-330]
- IPR016903: Nucleolar complex-associated protein 3 (family) [2-608]
- IPR005612: CCAAT-binding factor (domain) [315-533]
Interaction partners: - Nucleolar complex protein 2
- Nucleolar protein, putative
- Nucleolar GTP-binding protein 1
- NLE domain-containing protein
- Ribosome biogenesis protein, putative
- Pescadillo homolog
- Ribosome biogenesis protein BOP1 homolog
- Protein MAK16 homolog
- RNA-binding protein, putative
- Eukaryotic translation initiation factor 6
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0042254 (ribosome biogenesis), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0034470 (ncRNA processing), GO:0006364 (rRNA processing), GO:0034660 (ncRNA metabolic process), GO:0016072 (rRNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Acyl-acyl carrier protein thioesterase ATL4, chloroplastic (EC 3.1.2.-) (Acyl-ACP thioesterase ATL4) (Acyl-lipid thioesterase 4) (F4HX80)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acyl-ACP thioesterase involved in the production of fatty acids and beta-keto fatty acids. Can produce fatty acids of medium to long chain (6:0, 8:0, 10:0 and 16:1) and small amounts of medium to long chain beta-keto fatty acids (8:0, 14:0 and 16:1) when expressed in a heterologous organism (E.coli). Possesses thioesterase activity for lauroyl-ACP (12:0-ACP) in vitro. May play a role in the development of floral organs by generating short chain fatty acids.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:24214063}.
Sequence: MIRVTGTAAPAMSVVFPTSWRQPVMLPLRSAKTFKPHTFLDLKGGKEMSEFHEVELKVRDYELDQFGVVNNAVYANYCQHGMHEFLESIGINCDEVARSGEALAISELTMNFLAPLRSGDKFVVKVNISRTSAARIYFDHSILKLPNQEVILEAKATVVWLDNKHRPVRIPSSIRSKFVHFLRQNDTV
InterPro domains: - IPR029069: HotDog domain superfamily (homologous_superfamily) [48-186]
- IPR050563: 4-hydroxybenzoyl-CoA thioesterase (family) [29-186]
Interaction partners: - Chaperone protein dnaJ 39
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016790 (thiolester hydrolase activity), GO:0004312 (fatty acid synthase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0006629 (lipid metabolic process), GO:0044282 (small molecule catabolic process), GO:1901575 (organic substance catabolic process), GO:0044248 (cellular catabolic process), GO:0006082 (organic acid metabolic process), GO:0030258 (lipid modification), GO:0006631 (fatty acid metabolic process), GO:0016054 (organic acid catabolic process), GO:0044242 (cellular lipid catabolic process), GO:0043436 (oxoacid metabolic process), GO:0016042 (lipid catabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0046395 (carboxylic acid catabolic process), GO:0034440 (lipid oxidation), GO:0019395 (fatty acid oxidation), GO:0009062 (fatty acid catabolic process), GO:0072329 (monocarboxylic acid catabolic process), GO:0006635 (fatty acid beta-oxidation), GO:0032787 (monocarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Hxt5p (A0A1D8PSH1)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MSSVSSENNSGLFGTDVYDETKENKPKYEHEEGLEFGSDFDFDGEFEKYAAMGAAEKQSGAWMTNFKNLEFPLGVSPSVLVQTLGIFAAFCGILSGVDQSLISGASIGMDKSLHFNSHENSLVSSLMPLGAVAGSILLTPLQRFGRKKALMASCILYTIGAILCAAAPIPKELADGTFNNHRSRDVMYAGRFILGIGVGIEGGGVGVYISESVPSNKRGSLVSLYQLSIALGEVLGYAIAAIFYEVHGGWRFMVGSSLVFSTIVLIGLFFLPESPRYLVFKGKFGEAFNVFARLRDLGDRHSKIEFVQMVQAAEAERELRLTQNKSKVWFELVTIPRNRRALVYGIVMITLGQLTGINAVMYYLSTLMGRIGFSTKNSVFMSLVGGGSLLIGTIPAILYMDKFGRRVWGYNLVGFFVGLVLVGVGYSIDIETNLAAAEGVYLTGLILYMGFFGSYACLTWVVPAESFSLGTRSQGMTICSALLYLWAFTVTYNFNRMKVAMTYTGLTIGFYGGIAFLGFFYQVLFMPETKGKTLEEIDEIFEKPSRQLIKENLSGLKRFWGR
InterPro domains: - IPR036259: MFS transporter superfamily (homologous_superfamily) [76-545]
- IPR020846: Major facilitator superfamily domain (domain) [84-530]
- IPR005829: Sugar transporter, conserved site (conserved_site) [193-218]
- IPR050814: Myo-inositol Transporter (family) [61-552]
- IPR003663: Sugar/inositol transporter (family) [78-537]
- IPR005828: Major facilitator, sugar transporter-like (family) [86-541]
Interaction partners: - Hgt12p
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901618 (organic hydroxy compound transmembrane transporter activity), GO:0015166 (polyol transmembrane transporter activity), GO:0005365 (myo-inositol transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0015791 (polyol transmembrane transport), GO:0034219 (carbohydrate transmembrane transport), GO:0006810 (transport), GO:0015749 (monosaccharide transmembrane transport), GO:0071702 (organic substance transport), GO:0008645 (hexose transmembrane transport), GO:0015850 (organic hydroxy compound transport), GO:0008643 (carbohydrate transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: 40S ribosomal protein S21, putative (Q385B9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MATIGTYNEEGVNVDLYIPRKCHATNSLITSFDHSAVQIAIANVDPNGVIDGTTTTLCIAGYLRCQGESDHAINHLAIAKGIVRIKTGKKPRAKKTKNLKVASGARTQQKGGRNAAGQTKGAAQRGAAQKPTGRPQQAQRQGGRPARTEEGNRQRQGQQRQKPQQQQQQRQQQQQQRGGDRRAPQGRSGKAAPQRK
InterPro domains: - IPR001931: Small ribosomal subunit protein eS21 (family) [8-92]
- IPR038579: Small ribosomal subunit protein eS21 superfamily (homologous_superfamily) [1-90]
Interaction partners: - 40S ribosomal protein S14
- 40S ribosomal protein S33, putative
- 40S ribosomal protein S16, putative
- 40S ribosomal protein S5, putative
- 40S ribosomal protein S23, putative
- 40S ribosomal protein S26
- Small ribosomal subunit protein uS5
- 40S ribosomal protein S25
- 40S ribosomal protein S15a, putative
- 40S ribosomal protein S27, putative
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0019538 (protein metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006412 (translation), GO:0009059 (macromolecule biosynthetic process), GO:0006518 (peptide metabolic process), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:0010467 (gene expression), GO:0043043 (peptide biosynthetic process), GO:0002181 (cytoplasmic translation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: EG:100G10.5 protein (UDP-galactose transporter, isoform B) (O76865)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MALLPAPVTYSYSHRTVNANTLKYISLLTLTLQNAILGLSMRYARTRPGDIFLSSTAVLMAEFAKLITCLFLVFNEEGKDAQKFVRSLHKTIIANPMDTLKVCVPSLVYIVQNNLLYVSASHLDAATYQVTYQLKILTTAMFAVVILRRKLLNTQWGALLLLVMGIVLVQLAQTEGPTSGSAGGAAAAATAASSGGAPEQNRMLGLWAALGACFLSGFAGIYFEKILKGAEISVWMRNVQLSLLSIPFGLLTCFVNDGSRIFDQGFFKGYDLFVWYLVLLQAGGGLIVAVVVKYADNILKGFATSLAIIISCVASIYIFDFNLTLQFSFGAGLVIASIFLYGYDPARSAPKPTMHGPGGDEEKLLPRV
InterPro domains: - IPR037185: Multidrug transporter EmrE superfamily (homologous_superfamily) [105-173]
- IPR007271: Nucleotide-sugar transporter (family) [1-365]
Interaction partners: - Probable galactose-1-phosphate uridylyltransferase
- Protein Mo25
- UDP-glucose 4-epimerase
- GH11113p
- Hexosyltransferase
- Lysosomal dipeptide transporter MFSD1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015932 (nucleobase-containing compound transmembrane transporter activity), GO:1901505 (carbohydrate derivative transmembrane transporter activity), GO:0005338 (nucleotide-sugar transmembrane transporter activity), GO:0015165 (pyrimidine nucleotide-sugar transmembrane transporter activity), GO:0005459 (UDP-galactose transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0015780 (nucleotide-sugar transmembrane transport), GO:0034219 (carbohydrate transmembrane transport), GO:0006810 (transport), GO:0015749 (monosaccharide transmembrane transport), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:0090481 (pyrimidine nucleotide-sugar transmembrane transport), GO:0015931 (nucleobase-containing compound transport), GO:0008645 (hexose transmembrane transport), GO:0008643 (carbohydrate transport), GO:0072334 (UDP-galactose transmembrane transport), GO:1901264 (carbohydrate derivative transport), GO:0015711 (organic anion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098791 (Golgi apparatus subcompartment), GO:0031985 (Golgi cisterna), GO:0043231 (intracellular membrane-bounded organelle), GO:0005795 (Golgi stack), GO:0005797 (Golgi medial cisterna)