Protein: Diaphanous protein, homolog 1, putative (C4M1G6)
Organism: Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM)
Sequence: MSESNYVFRRVKLPARGDKLSSPFQKFDTSVPKKQLTVVGKQTGLNKNIKTKGGITAADLQSAKLSALPPTNYIDEKFKEISALFDISPNESNELSYETKWLLLQRHSPDASQSKLRNATFAVSSLRCEPTPTLIESIIVFLKNEKWSSQFIEADGVEALIDALTSSMNGSEKKNGAEVSRNCLRALRAIAPIAEDRVVKSTVCDLLMKCLTVNVADERIRTEATMLLCLISNKKKGSEEVLAAIDKVKGKEGRFKILVELFGKTDDSELKATIVAMFSYLTNNADDIFTRISRRAELTLSGFDEKCNGEKSKASLAMSKDVSDILNQIGIYEKLRGEDDAKMKERFKDIPMLSVEHTDEKLRGVLEQARAEIYYVQMLKEIEFLVGTDYTKNKNETILQQKLVVATRFIRQLGLYSYENDQHNTIEFNEHSIDINSLVSGAADCLGMAKLLEENATLKLSGGVKKTKIDDEEKEKLIQQKMEEMKKQSSLIAANEEKVTLKLKEVEEKEKKIALLESSQAALDGLKIKYDELNVQHNNTMEVMKILTKNPKLVDHLKAVGGVFAFSETAVQIADKSQEEVVNKEDLDRLKDAVLKLSPKGVVPPPSNTATAPPPPPPGASSVPPPPPPPGASSVPPPPPPPGASSVPPPPPPPGMPGMPPPPPPPGMPGMPPPPPLPGMPGMPPPPPGMPGMPPPPPGFGFRPPGAPALKVQTTLSKLKQPKNKLKAVQWQKIPERQLTNTIFSKMEGDVAVSECFDDLEEMFKQKEVVVKKEDTSKSNKIQYVGIFDGKKSQNINIMLNKFKGVSVETIIDNINALDMTLFDEVSLIEGLKNALPVASSDKDEPGLLKDYYEHPEKYVGKQLDPSEIFSYKLSQCSNAEKKLDVMMKLLQFPSKFDDCSRNVKTLLTASTQLCESKSFLKLLEVILIIGNYMNKASKKPITCGFKMSVLGKLADTKSNDNQKNLVYFLCKYIHEKHPDLSHWMEEVEAVVPAVRVMGSEVESTFAELKKTVAGFDSTIAQLQKTPGNEGFVAELSQLNSGYSTNMLVLENDKKKYDVQYSKVCQLYGEDTSKLPKSEDFFKNFKDFYESYEKAEQMYQDDKAKAEKEAKKEAEKKRKMEEQERKAKEREAKKKQQEAMVEGMAEDMIKPIKKVKKVKKSRKETMEVDFEKDLAEELKLAQDKPEDEPVKKVRKIVKRKVHKKATVATEEN
InterPro domains: - IPR015425: Formin, FH2 domain (domain) [716-1164]
- IPR010472: Formin, FH3 domain (domain) [236-434]
- IPR014768: Rho GTPase-binding/formin homology 3 (GBD/FH3) domain (domain) [66-421]
- IPR016024: Armadillo-type fold (homologous_superfamily) [74-421]
- IPR011989: Armadillo-like helical (homologous_superfamily) [66-350]
- IPR051412: Formin Homology Diaphanous subfamily (family) [648-1192]
- IPR010473: Formin, GTPase-binding domain (domain) [66-230]
- IPR042201: Formin, FH2 domain superfamily (homologous_superfamily) [721-1139]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0030029 (actin filament-based process), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0030036 (actin cytoskeleton organization), GO:0043933 (protein-containing complex organization), GO:0006996 (organelle organization), GO:0097435 (supramolecular fiber organization), GO:0007015 (actin filament organization), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly), GO:0007010 (cytoskeleton organization), GO:0008154 (actin polymerization or depolymerization), GO:0051017 (actin filament bundle assembly), GO:0061572 (actin filament bundle organization), GO:0051258 (protein polymerization), GO:0030041 (actin filament polymerization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0043229 (intracellular organelle), GO:0120025 (plasma membrane bounded cell projection), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015629 (actin cytoskeleton)