Protein: Chaski, isoform A (Chaski, isoform B) (Chaski, isoform C) (LD30953p) (MIP06944p) (Q8T043)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MAKLATDPNASNNNSCEAVNNNHNGQNQSQNGGASNYQALPLTPAPANTPLHKAIKHDLFPEVTFCNLSVEELADGAGHSRVVRSSVIELEDGTMTCLMNGNGQVKRRKRLISNESGDSIDSSSTEKKTPKMPDGGYGWVVVFASLVVSLIADGLSFSFGLINVELLEYFGESTSKTAWISSLFFSVPLLMGPIWSNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTFGIISGLGLGIGYVTAVVSIAFWFDKKRTFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLILGGTMLNACVCGALMRDPDWLIEENRLESRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVLDSLVTKNNTEANQQIDDPLDSALKRYRSEIFLPTFLSTQELDSICEVKSLSRRSLRHKEGEEAPSRENLLSMSSGAGAYPPSTAVIGSPDDTLMGGIAHEAAEEAKKAYLASIETLSPSEKRSTGRTPNGSLRSSDEGYLTQKHASSRYSLNENIFMAKHTTPSISNLKVNGLRHNSVDILSEDMHCYYSKDETFALLEPSRRIRPTVIAIPEQEQSVNSELATRRARLDSITGIRRLSRSKKPSHHRSNLRRNISIRNSNFLKDMRIHRNSIHYRGAMLNTHRYRLRASSCPNIYRNSMTTIAKEEEDTWYDNFVDTMKSIFDFSLFLDMKFALFNLSTLFLFIWFIIPYLYLPDYMKQYKYDVSQSAELISDVGIAQTVGMIGLGYLGDLSWMNINICYSLCMLVCGASVFFMPLLITNYMGLMVMCVIFGFTFASSFSFTPSILVSIVDLDDFTCAYGLVLLVQGVGMIAGPPIAGVIYEYTGRWDDTFYYAGIFIALSGVCSYLIEFCEKKAPKESDSDVLETKKAQLLH
InterPro domains: - IPR050327: Proton-linked Monocarboxylate Transporter (family) [133-872]
- IPR036259: MFS transporter superfamily (homologous_superfamily) [134-879]
- IPR020846: Major facilitator superfamily domain (domain) [685-894]
- IPR011701: Major facilitator superfamily (family) [150-880]
Interaction partners: - Uncharacterized protein, isoform D
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity), GO:0005342 (organic acid transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0046943 (carboxylic acid transmembrane transporter activity), GO:0008028 (monocarboxylic acid transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0032501 (multicellular organismal process), GO:0051234 (establishment of localization), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0055085 (transmembrane transport), GO:0009790 (embryo development), GO:1903825 (organic acid transmembrane transport), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0022008 (neurogenesis), GO:0010001 (glial cell differentiation), GO:0071705 (nitrogen compound transport), GO:0007399 (nervous system development), GO:1905039 (carboxylic acid transmembrane transport), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0009792 (embryo development ending in birth or egg hatching), GO:0015711 (organic anion transport), GO:0048699 (generation of neurons), GO:0043009 (chordate embryonic development), GO:0015849 (organic acid transport), GO:0046942 (carboxylic acid transport), GO:0015718 (monocarboxylic acid transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0045178 (basal part of cell), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0009925 (basal plasma membrane), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0016323 (basolateral plasma membrane)