Protein: Fork head domain-containing protein crocodile-like Protein (D6WIB6)
Organism: Tribolium castaneum (Red flour beetle)
Subcellular location: Nucleus
Sequence: MHTIFTEHQNAYYRPGGGYSTAAAAVTATANPYAYEQYSRYGYAAWHHQQHQLSTAKDMVKPPYSYIALIAMAIQNAPDKKITLNGIYQFIMERFPYYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFDNGSYLRRRRRFKKKDALREKEEAIKRQQLDSNVTAKRDEKPLEEAKKLECKPKREPAELTQCKYNDVKSVIVHQEHVISEAMAMDSAAAFTVDSLMTTREQHAYGNSGRLHTSGGMYYCPSATPQQYIGDEAAPRYSPWYSPETSPESGYRDMIFDSSAAPSCQLAGFRHSGVSPSPPNYRTAAAYYQQDCVGQKY
InterPro domains: - IPR018122: Fork head domain conserved site1 (conserved_site) [61-74]
- IPR050211: Forkhead box domain-containing protein (family) [36-299]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [47-156]
- IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [60-155]
- IPR001766: Fork head domain (domain) [59-155]
- IPR030456: Fork head domain conserved site 2 (conserved_site) [105-111]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0048519 (negative regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0048523 (negative regulation of cellular process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0009892 (negative regulation of metabolic process), GO:0001704 (formation of primary germ layer), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0048598 (embryonic morphogenesis), GO:0048729 (tissue morphogenesis), GO:0009888 (tissue development), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0009790 (embryo development), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0048333 (mesodermal cell differentiation), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0001707 (mesoderm formation), GO:0031326 (regulation of cellular biosynthetic process), GO:0007369 (gastrulation), GO:0048332 (mesoderm morphogenesis), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0051252 (regulation of RNA metabolic process), GO:0007498 (mesoderm development), GO:0051253 (negative regulation of RNA metabolic process), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:0010468 (regulation of gene expression), GO:2001141 (regulation of RNA biosynthetic process), GO:1902679 (negative regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903507 (negative regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045892 (negative regulation of DNA-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)