Protein: Testis-specific gene A8 protein (Q9JJL0)
Organism: Mus musculus (Mouse)
Subcellular location: Cytoplasm. Nucleus, nucleoplasm. Note=Strongly expressed in the nucleus of round spermatids. As spermatids mature, nuclear expression declines and cytoplasmic expression increases. Elongating spermatids have mainly cytoplasmic expression
Sequence: MDVPTSSTDSQEVKPIMPIRTKAACKFYPPHILCGKGAKTNKRGKRGGAQKASTKKDIGETTPPVAKKSKVAKEPTMLAAAAAPEAAASPESSAAAAAPEAAASPESSAAAAAPEAAASPESSAAAAAPEAAASLESSAAAAAPEAAAAPATPAAPEAAAAPEVAAAPATPAAPEATAAPAAPEAATTPAAPEAPAAAPAVEEEEMVWEAAAVVGEAAVKPPEEEPTSGEAVATTTMT
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0019953 (sexual reproduction), GO:0051321 (meiotic cell cycle), GO:0032259 (methylation), GO:0019222 (regulation of metabolic process), GO:0022402 (cell cycle process), GO:0006807 (nitrogen compound metabolic process), GO:0007049 (cell cycle), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0009892 (negative regulation of metabolic process), GO:0044237 (cellular metabolic process), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:1903046 (meiotic cell cycle process), GO:0048609 (multicellular organismal reproductive process), GO:0044238 (primary metabolic process), GO:0061982 (meiosis I cell cycle process), GO:0007276 (gamete generation), GO:0046483 (heterocycle metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0043414 (macromolecule methylation), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0007283 (spermatogenesis), GO:1901360 (organic cyclic compound metabolic process), GO:0140013 (meiotic nuclear division), GO:0006139 (nucleobase-containing compound metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0016043 (cellular component organization), GO:0044260 (cellular macromolecule metabolic process), GO:0007140 (male meiotic nuclear division), GO:0007141 (male meiosis I), GO:0007127 (meiosis I), GO:0010468 (regulation of gene expression), GO:0006306 (DNA methylation), GO:0043412 (macromolecule modification), GO:0090304 (nucleic acid metabolic process), GO:0006259 (DNA metabolic process), GO:0006996 (organelle organization), GO:0048232 (male gamete generation), GO:0010467 (gene expression), GO:0010629 (negative regulation of gene expression), GO:0016070 (RNA metabolic process), GO:0006304 (DNA modification), GO:0048285 (organelle fission), GO:0031047 (RNA-mediated gene silencing), GO:0006396 (RNA processing), GO:0034470 (ncRNA processing), GO:0070918 (regulatory ncRNA processing), GO:0000280 (nuclear division), GO:0006305 (DNA alkylation), GO:0034660 (ncRNA metabolic process), GO:0034587 (piRNA processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)