Protein: Leucine-rich HEV glycoprotein (Leucine-rich alpha-2-glycoprotein) (Q91XL1)
Organism: Mus musculus (Mouse)
Function: Not known
Sequence: MVSWQHQGSLQDLKTCLARTLFLLALLGRVSSLKECLILQSAEGSTVSCHGPTEFPSSLPADTVHLSVEFSNLTQLPAAALQGCPGLRELHLSSNRLQALSPELLAPVPRLRALDLTRNALRSLPPGLFSTSANLSTLVLRENQLREVSAQWLQGLDALGHLDLAENQLSSLPSGLLASLGALHTLDLGYNLLESLPEGLLRGPRRLQRLHLEGNRLQRLEDSLLAPQPFLRVLFLNDNQLVGVATGSFQGLQHLDMLDLSNNSLSSTPPGLWAFLGRPTRDMQDGFDISHNPWICDKNLADLCRWLVANRNKMFSQNDTRCAGPEAMKGQRLLDVAELGSL
InterPro domains: - IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [29-339]
- IPR050328: Multifunctional Developmental and Immune Receptor (family) [22-326]
- IPR003591: Leucine-rich repeat, typical subtype (repeat) [84-275]
- IPR001611: Leucine-rich repeat (repeat) [87-275]
- IPR000483: Cysteine-rich flanking region, C-terminal (domain) [292-342]
Interaction partners: - Endoglin
- Haptoglobin
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0050793 (regulation of developmental process), GO:0048856 (anatomical structure development), GO:0023056 (positive regulation of signaling), GO:0007275 (multicellular organism development), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0051239 (regulation of multicellular organismal process), GO:0006950 (response to stress), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:2000026 (regulation of multicellular organismal development), GO:0042127 (regulation of cell population proliferation), GO:0009611 (response to wounding), GO:0048468 (cell development), GO:0010646 (regulation of cell communication), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009966 (regulation of signal transduction), GO:0006952 (defense response), GO:0010647 (positive regulation of cell communication), GO:0008284 (positive regulation of cell population proliferation), GO:0022008 (neurogenesis), GO:0006954 (inflammatory response), GO:0007399 (nervous system development), GO:1901342 (regulation of vasculature development), GO:0045766 (positive regulation of angiogenesis), GO:0021782 (glial cell development), GO:0010001 (glial cell differentiation), GO:0007417 (central nervous system development), GO:1902533 (positive regulation of intracellular signal transduction), GO:0045765 (regulation of angiogenesis), GO:1902531 (regulation of intracellular signal transduction), GO:0042063 (gliogenesis), GO:0051896 (regulation of protein kinase B signaling), GO:0051897 (positive regulation of protein kinase B signaling), GO:0014068 (positive regulation of phosphatidylinositol 3-kinase signaling)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)