Protein: Asparagine synthetase domain-containing protein C4F6.11c (O74397)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Sequence: MCGILFALAEDRDNLLESPSFSALRKRIRARGPDFFGKHKLNSGPWNLHFESSVLHLRGPSDHLTPQPHVDSFGNVLCWNGEIWQINHSDHHKFTLNRNENDGAKLFELLNNNPGDIEKILGSIQGPFAFVYYQVRTNTLWWGRDRLGRRSLLYSLRDSNFVLSSVGNSSDFREVEPGFHSVQVDLIPKINFSKSLMQLEKTNPLPPVDESFLMGSISSDTVDTLHTYLIKALQDRVLTIPKLCSSNLDCSHYSRVCVLYSGGVDCGVLARLMHDIVPNNESIDLINVAFENPRFTETYRDRETGLLPDNFDAYDVCPDRQTGLQGWQELISVCPARKWNFVAINVPYTEVCEAQEIVKTLIYPNDSVMDLSIGLAFYFASQGRGVLLQNVDDIKLKHQLPSYTIKAKVLISGLGADEQLGGYMRHLRAFERKGMAGLEEELQLDIDRIPHRNLGRDDRVMSNQGKEVRYPFLDERLMALFSKMKTTDKMRLDLVGGDKLILRELGRRLGCPLASQEKKRAIQFGSKAAKMTPGTGRTSGRKKLEVCI
InterPro domains: - IPR029055: Nucleophile aminohydrolases, N-terminal (homologous_superfamily) [1-184]
- IPR001962: Asparagine synthase (domain) [255-526]
- IPR017932: Glutamine amidotransferase type 2 domain (domain) [2-193]
- IPR051857: Asparagine synthetase domain-containing protein (family) [1-535]
- IPR014729: Rossmann-like alpha/beta/alpha sandwich fold (homologous_superfamily) [216-539]
Interaction partners: - Glutamate synthase
- Probable asparagine synthetase
- CTP synthase
- Glutamine synthetase
- Tryptophan synthase
- Inosine-5'-monophosphate dehydrogenase
- Probable NAD-specific glutamate dehydrogenase
- Probable glutamate 5-kinase
- Probable NADPH:adrenodoxin oxidoreductase, mitochondrial
- Glutamyl-tRNA
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016874 (ligase activity), GO:0016879 (ligase activity, forming carbon-nitrogen bonds), GO:0016884 (carbon-nitrogen ligase activity, with glutamine as amido-N-donor)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0090304 (nucleic acid metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0018130 (heterocycle biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0010467 (gene expression), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0016070 (RNA metabolic process), GO:0090305 (nucleic acid phosphodiester bond hydrolysis), GO:0032774 (RNA biosynthetic process), GO:0097659 (nucleic acid-templated transcription), GO:0006396 (RNA processing), GO:0090501 (RNA phosphodiester bond hydrolysis), GO:0034470 (ncRNA processing), GO:0031123 (RNA 3'-end processing), GO:0006351 (DNA-templated transcription), GO:0006353 (DNA-templated transcription termination), GO:0034660 (ncRNA metabolic process), GO:0042780 (tRNA 3'-end processing), GO:0006399 (tRNA metabolic process), GO:0006383 (transcription by RNA polymerase III), GO:0008033 (tRNA processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)