Protein: Probable alpha-glucosidase AglA (Maltase) (Glucoinvertase) (Glucosidosucrase) (Maltase-glucoamylase) (Lysosomal alpha-glucosidase) (Acid maltase) (O53198)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Not known
Sequence: MDQHQRPDPMGPGSPRASARRPEPDPMGEPWWSRAVFYQVYPRSFADSNGDGVGDLDGLASRLDHLQQLGVDAIWINPVTVSPMADHGYDVADPRDIDPLFGGMPAFERLVAAAHRQGIKVTMDVVPNHTSSAHPWFQAALADLPGSPARDRYFFRDGRGPDGSLPPNNWESVFGGPAWTRVREPDGNPGQWYLHLFDTEQPDLNWDNPEILDDFEKTLRFWLDRGVDGFRIDVAHGMAKPPGLPDSPDLGIEVLHHRDDDPRFNHPNVHAIHRDIRTVIDEYPGAVTVGEVWVHDNARWAEYLRPDELHLGFNFRLARTEFDAAEIRDAVANSLAAAALQNATPTWTLANHDVGREVSRYGGGEIGLRRAKAMAVVMLALPGVVFLYNGQELGLPDVDLPDEVLQDPTWERSGRTERGRDGCRVPIPWSGNIPPFGFSTCPDTWLPMPPEWAALTAEKQRADAGSTLSFFRLALRLRRERNEFDGDVDWLAAPDDALIFRRHGGGLVCALNAAERPLALPAGEPILASAPLTDATLPPNAAAWLV
InterPro domains: - IPR017853: Glycoside hydrolase superfamily (homologous_superfamily) [30-484]
- IPR006047: Glycosyl hydrolase family 13, catalytic domain (domain) [39-482]
- IPR045857: Oligo-1,6-glucosidase, domain 2 (homologous_superfamily) [131-208]
Interaction partners: - Maltokinase
- 4-alpha-glucanotransferase
- Group 2 truncated hemoglobin GlbO
- Probable beta-glucosidase BglS
- Trehalose synthase/amylase TreS
- Uncharacterized glycosyl hydrolase Rv2006
- Uncharacterized transporter Rv1979c
- Probable cationic amino acid transport integral membrane protein RocE
- Possible cationic amino acid transport integral membrane protein
- Probable conserved integral membrane alanine and valine and leucine rich protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016853 (isomerase activity), GO:0016787 (hydrolase activity), GO:0016866 (intramolecular transferase activity), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds), GO:0015926 (glucosidase activity), GO:0090599 (alpha-glucosidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044248 (cellular catabolic process), GO:0044249 (cellular biosynthetic process), GO:0005975 (carbohydrate metabolic process), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0044262 (cellular carbohydrate metabolic process), GO:0044275 (cellular carbohydrate catabolic process), GO:0009057 (macromolecule catabolic process), GO:0009311 (oligosaccharide metabolic process), GO:0016051 (carbohydrate biosynthetic process), GO:0005976 (polysaccharide metabolic process), GO:0034637 (cellular carbohydrate biosynthetic process), GO:0016052 (carbohydrate catabolic process), GO:0044264 (cellular polysaccharide metabolic process), GO:0005984 (disaccharide metabolic process), GO:0005991 (trehalose metabolic process), GO:0000272 (polysaccharide catabolic process), GO:0006073 (cellular glucan metabolic process), GO:0009312 (oligosaccharide biosynthetic process), GO:0044042 (glucan metabolic process), GO:0046351 (disaccharide biosynthetic process), GO:0044247 (cellular polysaccharide catabolic process), GO:0005992 (trehalose biosynthetic process), GO:0009251 (glucan catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)