Protein: Serine/threonine-protein kinase BSK4 (EC 2.7.11.1) (Brassinosteroid-signaling kinase 4) (F4HU55)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable serine/threonine kinase that acts as positive regulator of brassinosteroid (BR) signaling downstream of the receptor kinase BRI1. Functions redundantly with BSK3, BSK6, BSK7 and BSK8.
Subcellular location: Cell membrane {ECO:0000305|PubMed:12912986}; Lipid-anchor {ECO:0000305|PubMed:12912986}.
Sequence: MGGQSSKIGTCCSHKTTALEAPDVENKENGEVNGVHSFREYSLEQLKIATSCFALENVVSEHGETAPNVVYQGKLENHMKIAIKRFSGTAWPDPRQFLEEARLVGQLRSKRMANLLGYCCEGGERLLVAEFMPNETLAKHLFHWDTEPMKWAMRLRVALYISEALEYCSNNGHTLYHDLNAYRVLFDEECNPRLSTFGLMKNSRDGKSYSTNLAFTPPEYLRTGRITAESVIYSFGTLLLDLLTGKHIPPSHALDLIRDRNLQTLTDSCLEGQFSDSDGTELVRLTSCCLQYEARERPNIKSLVTALISLQKDTEVLSHVLMGLPQSGTFASPPSPFAEACSGKDLTSMVEILEKIGYKDDEDLSFMWTEQMQEAINSKKKGDIAFRRKDFSEAIEFYTQFLDLGMISATVLVRRSQSYLMSNMAKEALDDAMKAQGISPVWYVALYLQSAALSVLGMEKESQIALTEGSILEARKISASTQN
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [29-318]
- IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [372-482]
- IPR045845: Serine/threonine-protein kinase BSK (family) [1-476]
- IPR001245: Serine-threonine/tyrosine-protein kinase, catalytic domain (domain) [63-307]
- IPR000719: Protein kinase domain (domain) [56-322]
Interaction partners: - Serine/threonine-protein phosphatase BSU1
- Protein BRASSINOSTEROID INSENSITIVE 1
- BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1
- Shaggy-related protein kinase eta
- Shaggy-related protein kinase iota
- Protein BRASSINAZOLE-RESISTANT 1
- Putative acyl-activating enzyme 19
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0050794 (regulation of cellular process), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0007165 (signal transduction), GO:0007154 (cell communication), GO:0071495 (cellular response to endogenous stimulus), GO:1901700 (response to oxygen-containing compound), GO:0009755 (hormone-mediated signaling pathway), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0009725 (response to hormone), GO:0048545 (response to steroid hormone), GO:0009741 (response to brassinosteroid), GO:0032870 (cellular response to hormone stimulus), GO:0014070 (response to organic cyclic compound), GO:0071310 (cellular response to organic substance), GO:0033993 (response to lipid), GO:1901701 (cellular response to oxygen-containing compound), GO:0043401 (steroid hormone mediated signaling pathway), GO:0071367 (cellular response to brassinosteroid stimulus), GO:0071383 (cellular response to steroid hormone stimulus), GO:0071396 (cellular response to lipid), GO:0071407 (cellular response to organic cyclic compound), GO:0009742 (brassinosteroid mediated signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)