Protein: Unconventional myosin-IXa-like (F0IWT2)
Organism: Caenorhabditis elegans
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Sequence: MSFDSISAGATGCFPRRAHTINATDDAHTHTVAVYMHSFNPDCENDTVHLEVHKRCTTEELIEKVLAGRAELEGQSVQDFDLFEMMGTPDGQTYKERRLDPGEYPVAVQAIWSRLPVVVDSATPKNRFVFRHRGYRAATGGTRFGSAEVASSIDAFLTKFLVQPQDREYADLCNLPELTEQTLLDNLRERFANGHIYTYIGPILVAVNPFCFFPIYNPKYARLYFQSKRLGSLPPHIFAIADVCYHNMLRIKENQCVVISGESGSGKTESTNHLMSHLISLSQKGSTGCSTEQTLLSAGPVLEAFGNAVTLTNNNSSRFGKFIKINYRENGMVSGANVEIYLLEKSRIIFQTKGERNYHVFYYLLEGADEEERKKYFLLKPHDYKYLNQNEPFALEGVNERNEFDRLRHAMSSVGFCAKTQQTIFGIISAVLLLGNITYIKRHGYHSDESGYIENEEVVDLVANLLHIKTDTLMQALTMKRHVMKTETVVLRYSVSEATNTRDAMAKCIYNSLFHYIVLRINQALLKKDFSAGKGYYIGILDIFGFEDVGSQCNSFEQLCINYANEKLQSYFNQHIFQFEQEEYLKEGISWTNIEYTDNTECVQLFQSKPYGILRLVDEESNINNGTDDSMLAKLNQFLKNNEYYETPQKKEPAFIVAHYAGKVKYQITGFREKNKDLMRQDVLNALKSSTSSVMKTLLGIDPVAVHRWNVLRSVFRAMNAFKQSTRKLQKSESAGHLRVMDSIVTSPRRGSDSALSAFLRGELRCEVPDFCDTSMFNTIRNQARRTPAGKSDDKMSLLKSLQILKEAIGGRRLAKKPSSVSKQFEYSLTRLMSTLANATPYFIRCIKSNNDKIANHFDDNIILRQLRYTGMLETVRIRRAGYSVRIEYPSFVQQYRILLRNGRDSTVDDVKEYIHSHASIDNDNIQYGTNKIFMRDAEKLILDDHLHRTIMQSIDTLQRWFRTMLARKRYLRMKEGIIKIQALIRGSFARAEVRKKALAAQTIQCNWKKYKQRQKYLSIRESVIALQSAYRGASVRKRVGEIPKGNGALNVKKSPFRVRKVHAVNLTKFDLSDPSSLAAFALSDDDSDSDKSTQDGLDDDISEESDAFQDDDAVDVDATFILEDTKLKLIEGADLSHHRRQSLAPTASTTKLKMLRRANSTESNNFSMSRCDDSFTLSPTHSKKKGGAGKLGFQKAKKNLKALFGRNEDEDEPSPGPSFASELTPDVFVAKDHQFKMSRLHRQEICALCNRHLTNFISQAHKCQRCKMCLHKECFVFASSIPCNPTSPVRSPTRLHSPKRPWDLMPHKQRQSSSPIPSTGTFSLTKTKQQIDPGNMLVESTDDLRQFSIFIFNKTRHLNESNAKRDTVVDAVFKKSLRAFHMELLGYEAVLSVEQSVLKYRDVITMFEGLLTKVCLEESVSFPTTLGVNAFRGFLNEYVHVQSKKKRGKEKSSMIKKVGKKRVKSDVAAVHAGHRFRAEAVHVPTYCEVCNQLIWHHEKLYTCVACRISCHKKCQPKVTHPCQMTGKAIDPKTNGGRFFGASLVSIVDDDHTVPTLLDRLFFAIETRALFVEGVYRKSGSLPQVRSIRKVIESTADADSVNLEDIGVHVLTTLVKAFFRELAEPIIIFDLYENFLNVSEVEDMGERVRCLSVMIELLPKPNRAVLDRLMYHLARVADQEAVNKMGCNNLALIFGPCVLRRQDSAHAQEQLNDVARQTGCVQTLIEEKLKQYKATIHNIVELEDASQKVSANLRKIEEHRRNSEPSKFSPNIGTAKQLFEEQLEFLGKQKERLLQELPPLAPVASSEDLSSSDENAIHASSSLSVEEYALDLDAPPVFCLLRYPTKLRPPGPAHRRRPDLDLRRKAFANSRGIVSFYSPV
InterPro domains: - IPR046349: C1-like domain superfamily (homologous_superfamily) [1220-1525]
- IPR000048: IQ motif, EF-hand binding site (binding_site) [950-1041]
- IPR029071: Ubiquitin-like domain superfamily (homologous_superfamily) [29-133]
- IPR046987: Unconventional class IX myosin (family) [23-1175]
- IPR036023: Class IX myosin, motor domain (domain) [181-936]
- IPR000159: Ras-associating domain (domain) [28-135]
- IPR002219: Protein kinase C-like, phorbol ester/diacylglycerol-binding domain (domain) [1233-1525]
- IPR000198: Rho GTPase-activating protein domain (domain) [1542-1732]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [167-1000]
- IPR001609: Myosin head, motor domain-like (domain) [161-949]
- IPR036961: Kinesin motor domain superfamily (homologous_superfamily) [171-882]
- IPR008936: Rho GTPase activation protein (homologous_superfamily) [1533-1744]
Interaction partners: - Ras-like GTP-binding protein rhoA
- Cell division control protein 42 homolog
- CHp/Wrch Rho-like protein homolog
- Rho-GAP domain-containing protein
- Ras-related protein ced-10
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003774 (cytoskeletal motor activity), GO:0140657 (ATP-dependent activity), GO:0005515 (protein binding), GO:0000146 (microfilament motor activity), GO:0005516 (calmodulin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0030029 (actin filament-based process), GO:0030048 (actin filament-based movement), GO:0070252 (actin-mediated cell contraction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0099080 (supramolecular complex), GO:0016020 (membrane), GO:0055120 (striated muscle dense body), GO:0030017 (sarcomere), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0031672 (A band), GO:0043292 (contractile fiber), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0005886 (plasma membrane), GO:0043228 (non-membrane-bounded organelle), GO:0099081 (supramolecular polymer), GO:0043005 (neuron projection), GO:0099512 (supramolecular fiber), GO:0030016 (myofibril), GO:0043232 (intracellular non-membrane-bounded organelle)