Protein: DNAation factor-related protein 4 (Q9V3H0)
Organism: Drosophila melanogaster (Fruit fly)
Sequence: MISYIRDAIMSPTTRSSSNNKKSSQPTGEVLKDVSSSESRGTAGAPMRGYKVTDNERTRKYGIGANSLEMLIAKAKSKFPLLEPHLYLASDGFEVSDDEYLKSLPAQTLFIVSGPDAVITTDADFEFEKMRQQSPLLKVADIFYDFIEQHPEKFRRMITEYEHQKQRRVLDNSKTHLSLKAEHVEWFTGGEERFHSKEEAMATRAQTRVRGYYYKAKEELTRNPLYRQNAKARQVINSVLEKFRYLLIGCDFFSMMFDRNCKQKHEFLKQHLGDEETDAGRIPSKRLRQVIREYTKENCILDEWSTSLCSDLGDFYCQGSYSENGNSCSKQHTINPYASRENLILFQVWNLDHQIELCRTILPALVANVEELVSHPQTKCSIHKKQVVDISVLEYFLEIFSLKNLKLVHIVCHEKAQRSNRSNGRLLCSDCHEYRIVQELMEVQVDSLAT
InterPro domains: - IPR044925: His-Me finger superfamily (homologous_superfamily) [134-439]
- IPR039729: DNA fragmentation factor 40 (family) [41-447]
- IPR015311: DNA fragmentation factor 40, C-terminal (domain) [152-435]
- IPR003508: CIDE-N domain (domain) [46-121]
Interaction partners: - DNAation factor-related protein 1, isoform B
- DNAation factor-related protein 3, isoform A
- DNAation factor-related protein 2, isoform B
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016787 (hydrolase activity), GO:0140098 (catalytic activity, acting on RNA), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0004518 (nuclease activity), GO:0004540 (ribonuclease activity), GO:0004519 (endonuclease activity), GO:0004521 (RNA endonuclease activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0097194 (execution phase of apoptosis), GO:0008219 (cell death), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0012501 (programmed cell death), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0006921 (cellular component disassembly involved in execution phase of apoptosis), GO:0046483 (heterocycle metabolic process), GO:0044248 (cellular catabolic process), GO:0016043 (cellular component organization), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0034655 (nucleobase-containing compound catabolic process), GO:0009057 (macromolecule catabolic process), GO:0044270 (cellular nitrogen compound catabolic process), GO:0090304 (nucleic acid metabolic process), GO:0044265 (cellular macromolecule catabolic process), GO:0019439 (aromatic compound catabolic process), GO:1901361 (organic cyclic compound catabolic process), GO:0006915 (apoptotic process), GO:0046700 (heterocycle catabolic process), GO:0030262 (apoptotic nuclear changes), GO:0006259 (DNA metabolic process), GO:0022411 (cellular component disassembly), GO:0006308 (DNA catabolic process), GO:0006309 (apoptotic DNA fragmentation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)