Protein: Armadillo repeat-containing protein 8 (B7Z637)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MKNAVIGNNKQKANLIVLGAVPRLLYLLQQETSSTELKTECAVVLGSLAMGTENNVKSLLDCHIIPALLQGLLSPDLKFIEACLRCLRTIFTSPVTPEELLYTGPDHQTILFNHGAVQNIAHLLTSLSYKVRMQALKCFSVLAFENPQVSMTLVNVLVDGELLPQIFVKMLQRDKPIEMQLTSAKCLTYMCRAGAIRTDDNCIVLKTLPCLVRMCSKERLLEERVEGAETLAYLIEPDVELQRIASITDHLIAMLADYFKYPSSVSAITDIKRLDHDLKHAHELRQAAFKLYASLGANDEDIRKKIIETENMMDRIVTGLSESSVKVRLAAVRCLHSLSRSVQQLRTSFQDHAVWKPLMKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAVELLCGLTQSENPALRVNGIWALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHGKQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKDLIMTNDDILQKIKYYMGHSHVKLQLAAMFCISNLIWNEEEGSQERQDKLRDMGIVDILHKLSQSPDSNLCDKAKMALQQYLA
InterPro domains: - IPR016024: Armadillo-type fold (homologous_superfamily) [7-599]
- IPR038739: Armadillo-type fold containing protein ARMC8/Vid28 (family) [104-596]
- IPR011989: Armadillo-like helical (homologous_superfamily) [1-600]
- IPR000225: Armadillo (repeat) [8-600]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0051179 (localization), GO:0050789 (regulation of biological process), GO:0042592 (homeostatic process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0051641 (cellular localization), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0045494 (photoreceptor cell maintenance), GO:0048871 (multicellular organismal-level homeostasis), GO:0033036 (macromolecule localization), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0044238 (primary metabolic process), GO:0051302 (regulation of cell division), GO:0010171 (body morphogenesis), GO:0044085 (cellular component biogenesis), GO:1901564 (organonitrogen compound metabolic process), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0019538 (protein metabolic process), GO:0048513 (animal organ development), GO:0009966 (regulation of signal transduction), GO:0043170 (macromolecule metabolic process), GO:0060249 (anatomical structure homeostasis), GO:0045184 (establishment of protein localization), GO:0009887 (animal organ morphogenesis), GO:0010646 (regulation of cell communication), GO:0070727 (cellular macromolecule localization), GO:0016043 (cellular component organization), GO:0001894 (tissue homeostasis), GO:0030030 (cell projection organization), GO:0006508 (proteolysis), GO:0010256 (endomembrane system organization), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0090596 (sensory organ morphogenesis), GO:0001895 (retina homeostasis), GO:0048666 (neuron development), GO:0022607 (cellular component assembly), GO:0036211 (protein modification process), GO:0022008 (neurogenesis), GO:0043412 (macromolecule modification), GO:0007399 (nervous system development), GO:0008104 (protein localization), GO:0006996 (organelle organization), GO:0030182 (neuron differentiation), GO:1902531 (regulation of intracellular signal transduction), GO:0061024 (membrane organization), GO:0033365 (protein localization to organelle), GO:0048592 (eye morphogenesis), GO:0001654 (eye development), GO:0046530 (photoreceptor cell differentiation), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0150063 (visual system development), GO:0042461 (photoreceptor cell development), GO:0007030 (Golgi organization), GO:0048699 (generation of neurons), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0061512 (protein localization to cilium), GO:0043010 (camera-type eye development), GO:0001754 (eye photoreceptor cell differentiation), GO:0042462 (eye photoreceptor cell development), GO:0097499 (protein localization to non-motile cilium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0140535 (intracellular protein-containing complex), GO:0012505 (endomembrane system), GO:1902494 (catalytic complex), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0005576 (extracellular region), GO:0030141 (secretory granule), GO:1990234 (transferase complex), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0000151 (ubiquitin ligase complex), GO:0043227 (membrane-bounded organelle), GO:0060205 (cytoplasmic vesicle lumen), GO:0031983 (vesicle lumen), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0034774 (secretory granule lumen), GO:0042581 (specific granule), GO:0070820 (tertiary granule), GO:0070013 (intracellular organelle lumen), GO:0031982 (vesicle), GO:0035580 (specific granule lumen), GO:0097708 (intracellular vesicle), GO:0005634 (nucleus), GO:0031981 (nuclear lumen), GO:1904724 (tertiary granule lumen)