wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Cytochrome c2 (P86323)
Organism: Rhodoplanes tepidamans (Rhodoplanes cryptolactis)
Function: Cytochrome c2 is found mainly in purple, non-sulfur, photosynthetic bacteria where it functions as the electron donor to the oxidized bacteriochlorophyll in the photophosphorylation pathway. However, it may also have a role in the respiratory chain and is found in some non-photosynthetic bacteria.
Subcellular location: Periplasm {ECO:0000269|PubMed:20697695}.
Sequence: QQVAAGAVSFRKCTPCHNIGEGATNKVGPVLDGLEGRHSGSIPGFNYSEANKKSGLTWDKATFKSYIADPRAKIPGTKMVFAGIKNEKEQEDLWAFLTQYGPDGKKK
InterPro domains: - IPR009056: Cytochrome c-like domain (domain) [1-101]
- IPR036909: Cytochrome c-like domain superfamily (homologous_superfamily) [1-107]
- IPR002327: Cytochrome c, class IA/ IB (family) [5-99]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0046906 (tetrapyrrole binding), GO:0020037 (heme binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006091 (generation of precursor metabolites and energy), GO:0015979 (photosynthesis), GO:0022900 (electron transport chain), GO:0019684 (photosynthesis, light reaction), GO:0009767 (photosynthetic electron transport chain)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0042597 (periplasmic space)
Protein: Transcriptional regulatory protein WalR (I6L8Z5)
Organism: Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Sequence: MKKILIVDDEKPISDIIKFNLAKEGYDTITAFDGREALSKYEEENPDLIILDLMLPELDGLEVAKEVRKNSHVPIIMLSAKDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIESAVAEENASGIPEIIIGDLQILPDAFVAKKRGTEVELTHREFELLHHLATHTGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD
InterPro domains: - IPR001789: Signal transduction response regulator, receiver domain (domain) [2-116]
- IPR039420: Transcriptional regulatory protein WalR-like (family) [1-232]
- IPR047791: Transcriptional regulatory protein WalR (family) [2-233]
- IPR011006: CheY-like superfamily (homologous_superfamily) [1-126]
- IPR001867: OmpR/PhoB-type DNA-binding domain (domain) [134-233]
- IPR058071: WalR, receiver domain (domain) [4-118]
- IPR016032: Signal transduction response regulator, C-terminal effector (homologous_superfamily) [137-231]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [124-234]
Interaction partners: - histidine kinase
- Metallo-beta-lactamase domain-containing protein
- histidine kinase
- histidine kinase
- histidine kinase
- histidine kinase
- UDP-N-acetylglucosamine 2-epimerase
- Glucosyltransferase-SI
- Glucosyltransferase-S
- histidine kinase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0003676 (nucleic acid binding), GO:0001217 (DNA-binding transcription repressor activity), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0032993 (protein-DNA complex)
Protein: Vasopressin-neurophysin 2-copeptin precursor (Vasotocin-neurophysin) (Q8AV79)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Sequence: MSDSLLSVCVLCVLALSTLSSACYIQNCPRGGKRSQPEPIRQCMSCGPGGVGRCFGPSICCGPGLGCVLGSPEAQVCMEEEQLSGPCETGGTSCGDRGGRCAAEGICCDSESCAVDPDCPEGSSAGLKSISGETLLRLLNLATRRQRPF
InterPro domains: - IPR022423: Neurohypophysial hormone, conserved site (conserved_site) [23-31]
- IPR036387: Neurohypophysial hormone domain superfamily (homologous_superfamily) [38-127]
- IPR000981: Neurohypophysial hormone (family) [1-148]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (signaling receptor activator activity), GO:0048018 (receptor ligand activity), GO:0005179 (hormone activity), GO:0005184 (neuropeptide hormone activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:1901700 (response to oxygen-containing compound), GO:1901698 (response to nitrogen compound), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0009314 (response to radiation), GO:0043434 (response to peptide hormone), GO:1901652 (response to peptide), GO:0009416 (response to light stimulus), GO:0010243 (response to organonitrogen compound), GO:0032868 (response to insulin)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Cyclin-G2 (O08918)
Organism: Mus musculus (Mouse)
Function: May play a role in growth regulation and in negative regulation of cell cycle progression.
Subcellular location: Cytoplasm. Nucleus. Note=Primarily found in the cytoplasm. A minor portion can be detected in some cells in the nucleus.
Sequence: MKDLGAKHLAGGEGVQLFGLLNFYLEQEQRYQPREKGLILMEATPENDNTLCSRLRNAKVEDLRSLTNFFGSGTETFVLAVNILDRFLALMKVKPKHLSCIGVCCFLLAARLAEEEGDVPPTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLYHAIVFCHTSERKEILSLDKLEAQLKACNCRVVFSKARPSVLALCLLNLEIETIKSVELLEILLLVKKHLKLSDTEFFYWRELVSKCLAEYSSPRCCKPDLKKLVWIVSRRTAQNLHSSYYSVPELPTIPEGGCFDGSESEDSGEDMSCGEESLSSSPPSDQECTFFFDFQVAQTLCFPP
InterPro domains: - IPR013763: Cyclin-like domain (domain) [61-147]
- IPR039361: Cyclin (family) [51-237]
- IPR006671: Cyclin, N-terminal (domain) [21-153]
- IPR036915: Cyclin-like superfamily (homologous_superfamily) [21-153]
Interaction partners: - Cyclin-G1
- E3 ubiquitin-protein ligase Mdm2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0065009 (regulation of molecular function), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0051726 (regulation of cell cycle), GO:0060255 (regulation of macromolecule metabolic process), GO:0050790 (regulation of catalytic activity), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051338 (regulation of transferase activity), GO:1904029 (regulation of cyclin-dependent protein kinase activity), GO:0051246 (regulation of protein metabolic process), GO:0051174 (regulation of phosphorus metabolic process), GO:0000079 (regulation of cyclin-dependent protein serine/threonine kinase activity), GO:0043549 (regulation of kinase activity), GO:0031399 (regulation of protein modification process), GO:0019220 (regulation of phosphate metabolic process), GO:0042325 (regulation of phosphorylation), GO:0001932 (regulation of protein phosphorylation), GO:0045859 (regulation of protein kinase activity), GO:0071900 (regulation of protein serine/threonine kinase activity)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Pcdha1 protein (Protocadherin alpha 1) (Q641K6)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Sequence: MLFSRLRGLRARRLLLFSLLFLAAWEAGSGQIHYSVPEEAKHGTFVGRIAQDLGLELTELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVKDINDNPPVFKGAEQRIFIPENRQLDSRFPLEGAVDADIGANSLLTYTLSPTDYFSLKVETTDELSKSLSLELRKSLDREETPELQLLLTATDGGKPELEGTVRLQITVLDVNDNAPLFDQAIYRAQLVESTVNGTLVTTLNATDADEGVNGEVVFSFGNDVSLDIQEKFNVDSLSGEIRVIGDLDYEKTKSYEIQIKAVDKGTPSMSNHCKVLVKVLDINDNAPELSITSLSLPIKEDTPLNTIIALIKVSDIDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSTLDRETTADYKVVVTARDGGSPSLWATASVSVEVADVNDNAPVFAQPEYTVFVKENNPPGAHIFTVSAMDADAQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLQFQVSARDAGVPALGSNVTLQVFVLDENDNPPTLLGPHAGSAVSELVSRTMGAGHVVTKVRAVDADSGYNAWLSYELQPPTGGARNPFRVGLYTGEISTTRSLDEVDVPRQRLLVLVKDHGEPMLTATATVLVSLVESSPIQKASLPVLTGAVGSKASLVDVNVYLIIAICAVSSLLVLTLLLYTALRCSATPTDGACGPGKPMLVCSSAVGSWSYSQQRRQKVCSGEGPPKTDLMAFSPGLAPGLNIAERSDHAEVNSDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPEPKKQTQVSFLPRRKGEASQPRQ
InterPro domains: - IPR050174: Protocadherin/Cadherin-related Cell Adhesion (family) [17-757]
- IPR002126: Cadherin-like (domain) [22-681]
- IPR031904: Cadherin, C-terminal catenin-binding domain (domain) [798-882]
- IPR013164: Cadherin, N-terminal (domain) [31-112]
- IPR015919: Cadherin-like superfamily (homologous_superfamily) [31-666]
- IPR020894: Cadherin conserved site (conserved_site) [231-564]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0005509 (calcium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhesion), GO:0098609 (cell-cell adhesion), GO:0098742 (cell-cell adhesion via plasma-membrane adhesion molecules), GO:0007156 (homophilic cell adhesion via plasma membrane adhesion molecules)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)
Protein: Hormone receptor 83 (RT11831p) (Q9VI12)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MSNFSACAVCGDQSSGKHYGVSCCDGCSCFFKRSVRRGSSYACIALVGNCVVDKARRNWCPSCRFQRCLAVGMNAAAVQEERGPRNQQVALYRTGRRQAPPSQAAPSPTPHSQALHFQILAQILVTCLRQAKANEQFALLDRCQQDAIFQVVWSEIFVLRASHWSLDISAMIDGCGDEQLKRLICEAHQLRADVLELNFMESLILCRKELAINAEYAVILGSHSKAALISLARYTLQQSNYLRFGQLLLGLRQLCLRRFDCALSCMFRSVVRDILKTL
InterPro domains: - IPR050274: Nuclear hormone receptor family NR2 subfamily (family) [6-258]
- IPR001628: Zinc finger, nuclear hormone receptor-type (domain) [4-80]
- IPR035500: Nuclear hormone receptor-like domain superfamily (homologous_superfamily) [77-276]
- IPR013088: Zinc finger, NHR/GATA-type (homologous_superfamily) [1-103]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0042742 (defense response to bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Protein VCF2 (VCP nuclear cofactor family member 2) (Q5XKR9)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MGGCPVRKRRRNGSKEGNHHSTQPKRNKRNPIFQDSQDTEFSWSDNERSSSRINIPERASGPEGNLNQIVTEPDANFPQFLHEGLSKPVYVINWFMSFGPEIKLNTSQQGRNQAV
InterPro domains: - IPR029222: VCF1/2-like (family) [6-113]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023056 (positive regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010647 (positive regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0010646 (regulation of cell communication), GO:0030111 (regulation of Wnt signaling pathway), GO:0030177 (positive regulation of Wnt signaling pathway), GO:0060828 (regulation of canonical Wnt signaling pathway), GO:0090263 (positive regulation of canonical Wnt signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Putative galactosidae (Q8W4Z8)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Function: Not known
Sequence: CTLGPLDEFGLQREPKWGHLKDVHRALSLCKRALFWGFPTTLKLGPDQQAIVWQQPGTSACAALLANNNTRLAQHVNFRGQDIRLPARSISVLPDCKTVVFNTQLVTTQHNSRNFVRSEIANKNFNWEMYREVPPVGLGFKFDVPRELFHLTKDTTDYAWYTTSLLLGRRDLPMKKNVRPVLRVASLGHGIHAYVNGEYAGSAHGSKVEKSFVCRELSSLKEGENHIALLGYLVGLPDSGAYMEKRFAGPRSITILGLNTGTLDISQNGWGHQVGTDGEKKKLFTEEGSKSVQWTKPDQGGPLTWYKGYFDAPEGDNPVAIVMTGMGKGMVWVNGRSIGRYWNNYLSPLKKPTQSEYHIPRAYLKPKNLIVLLEEEGGNPKDV
InterPro domains: - IPR001944: Glycoside hydrolase, family 35 (family) [5-382]
- IPR048913: Beta-galactosidase, galactose-binding domain (domain) [303-367]
- IPR041392: Beta-galactosidase, beta-sandwich domain (domain) [50-106]
- IPR008979: Galactose-binding-like domain superfamily (homologous_superfamily) [90-381]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0097367 (carbohydrate derivative binding), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0016787 (hydrolase activity), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0005515 (protein binding), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0043168 (anion binding), GO:0000166 (nucleotide binding), GO:0043169 (cation binding), GO:0032553 (ribonucleotide binding), GO:0035639 (purine ribonucleoside triphosphate binding), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds), GO:0032555 (purine ribonucleotide binding), GO:0046872 (metal ion binding), GO:0017076 (purine nucleotide binding), GO:0005524 (ATP binding), GO:0046914 (transition metal ion binding), GO:0032559 (adenyl ribonucleotide binding), GO:0030554 (adenyl nucleotide binding), GO:0005507 (copper ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0009791 (post-embryonic development), GO:0048316 (seed development), GO:0090376 (seed trichome differentiation), GO:0048608 (reproductive structure development), GO:0009888 (tissue development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0090558 (plant epidermis development), GO:0061458 (reproductive system development), GO:0010026 (trichome differentiation), GO:0010154 (fruit development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Protease inhibitor HPI (HbPI1) (Protease inhibitor 1) (Q6XNP7)
Organism: Hevea brasiliensis (Para rubber tree) (Siphonia brasiliensis)
Function: Inhibitor of serine proteases, strongly inhibits subtilisin A and weakly inhibits trypsin. Does not inhibit chymotrypsin, papain, pepsin, pronase E, protease type XIII and thermolysin. HPI-1 inhibits subtilisin A with an Ki of 0.21 nM. HPI-2a inhibits subtilisin A with an Ki of 0.08 nM. HPI-2b inhibits subtilisin A with an Ki of 0.1 nM.
Sequence: MASQCPVKNSWPELVGTNGDIAAGIIQTENANVKAIVVKEGLPITQDLNFNRVRVFVDENRVVTQVPAIG
InterPro domains: - IPR000864: Proteinase inhibitor I13, potato inhibitor I (family) [5-70]
- IPR036354: Proteinase inhibitor I13, potato inhibitor I superfamily (homologous_superfamily) [4-70]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140678 (molecular function inhibitor activity), GO:0061134 (peptidase regulator activity), GO:0004857 (enzyme inhibitor activity), GO:0061135 (endopeptidase regulator activity), GO:0030414 (peptidase inhibitor activity), GO:0004866 (endopeptidase inhibitor activity), GO:0004867 (serine-type endopeptidase inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009620 (response to fungus), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0050832 (defense response to fungus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Proteasome chaperone 3 (Increased recombination centers protein 25) (Q07951)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in 20S proteasome assembly, facilitating the alpha-ring formation.
Sequence: MISYEFQTHLPKGKDSSLNASSENKELYVQATHFNNTILLQIRLNGEMDSTYEVSSKGLNPILDINVPLAGNLGNTGGDYDDEEEEFVRDHLSDYQVVTKLGDSADPKVPVVCVQIAELYRRVILPEVSGTMAQDNMQFSLLISMSSKIWRATKEQSADDNDFGKLVFVLKCIKDMYAK
InterPro domains: - IPR053720: Proteasome Assembly Chaperone (homologous_superfamily) [1-179]
- IPR018854: Proteasome chaperone 3/4 (family) [1-174]
Interaction partners: - Proteasome chaperone 4
- Proteasome subunit alpha type-5
- Proteasome chaperone 1
- Proteasome assembly chaperone 2
- Proteasome maturation factor UMP1
- Proteasome subunit alpha type-4
- Proteasome subunit alpha type-3
- Proteasome activator BLM10
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0043933 (protein-containing complex organization), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly), GO:0043248 (proteasome assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: WD_REPEATS_REGION domain-containing protein (Q17872)
Organism: Caenorhabditis elegans
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MAVVTITTDTEDSEIPQRTEVGSSTPLVDEIMQHADVKLSKILFTGETSSQIISLGKGRGRCISLWERDDGIDPFKVLATKNSEIDPNDACTMTDNRVCIGYADGSLAVFSTDKDDLALMSRIPSIHSGSASRKICRHGNSILSASSNGSLVAVDVETGMPRTIFTGQAGIRSVCTTFGTNVVMAGDANGQITMWDLRENNEHSNTLDPIKTLIPSKKALDAVTALCSHPAQSNLVCCGTDDGIVGLIDARNVRGANITSTYLVAKKAISQVMFHPKCGDNLLVSSNDGSLIRIDASGAPIAVGPRSTKDTIWLEGDLVNSLRLDPIRNESVHSISSFDIRSDTVVTASSIGLISLYQQLPFFPNSNFGRF
InterPro domains: - IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [33-361]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [55-358]
- IPR001680: WD40 repeat (repeat) [158-295]
Interaction partners: - Nuclear Pore complex Protein
- Nuclear pore complex protein 5
- Nuclear pore complex protein Nup85
- Nuclear pore complex protein 15
- Nsp1_C domain-containing protein
- Protein SEC13 homolog
- Nucleoporin SEH1
- Nucleoporin_N domain-containing protein
- Nuclear pore protein
- Nuclear pore complex protein Nup98-Nup96
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0046907 (intracellular transport), GO:0051649 (establishment of localization in cell), GO:0006810 (transport), GO:0051169 (nuclear transport), GO:0006913 (nucleocytoplasmic transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0035770 (ribonucleoprotein granule), GO:0036464 (cytoplasmic ribonucleoprotein granule), GO:0043229 (intracellular organelle), GO:0045495 (pole plasm), GO:0043228 (non-membrane-bounded organelle), GO:0043186 (P granule), GO:0060293 (germ plasm), GO:0043232 (intracellular non-membrane-bounded organelle)