Protein: Rho-related BTB domain-containing protein 1 (O94844)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MDADMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDEVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGLPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPPPVIKIPECPSMGTNEAACLLDNPLCADVLFILQDQEHIFAHRIYLATSSSKFYDLFLMECEESPNGSEGACEKEKQSRDFQGRILSVDPEEEREEGPPRIPQADQWKSSNKSLVEALGLEAEGAVPETQTLTGWSKGFIGMHREMQVNPISKRMGPMTVVRMDASVQPGPFRTLLQFLYTGQLDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMNQEITKAFHVRKANRIKECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVESANSEVYLPNINKISMQAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQELTKAATSGVGIDGEVLSYLELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSADNQEYFERHRWPPVWYLKEEDHYQRVKREREKEDIALNKHRSRRKWCFWNSSPAVA
InterPro domains: - IPR003578: Small GTPase Rho (family) [14-218]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [11-216]
- IPR000210: BTB/POZ domain (domain) [266-583]
- IPR011333: SKP1/BTB/POZ domain superfamily (homologous_superfamily) [241-630]
- IPR001806: Small GTPase (family) [8-325]
Interaction partners: - Cullin-3
- Kelch-like ECH-associated protein 1
- Kelch-like protein 13
- Kelch-like protein 9
- Rho-related BTB domain-containing protein 2
- Rho-associated protein kinase 1
- NEDD8-conjugating enzyme Ubc12
- COP9 signalosome complex subunit 1
- COP9 signalosome complex subunit 6
- cGMP-specific 3',5'-cyclic phosphodiesterase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0050789 (regulation of biological process), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0071840 (cellular component organization or biogenesis), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0051649 (establishment of localization in cell), GO:0016043 (cellular component organization), GO:0060627 (regulation of vesicle-mediated transport), GO:0051049 (regulation of transport), GO:0046907 (intracellular transport), GO:0006810 (transport), GO:0016482 (cytosolic transport), GO:0016192 (vesicle-mediated transport), GO:0016197 (endosomal transport), GO:0006996 (organelle organization), GO:0010256 (endomembrane system organization), GO:0042147 (retrograde transport, endosome to Golgi), GO:0016050 (vesicle organization), GO:0007032 (endosome organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0005622 (intracellular anatomical structure), GO:0016020 (membrane), GO:0005576 (extracellular region), GO:0005615 (extracellular space), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0005794 (Golgi apparatus), GO:0031090 (organelle membrane), GO:0043229 (intracellular organelle), GO:0070062 (extracellular exosome), GO:0043227 (membrane-bounded organelle), GO:0043230 (extracellular organelle), GO:0098791 (Golgi apparatus subcompartment), GO:0065010 (extracellular membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0032588 (trans-Golgi network membrane), GO:0031982 (vesicle), GO:0005802 (trans-Golgi network), GO:1903561 (extracellular vesicle)