Protein: Cell surface glycoprotein CD200 receptor 4 (CD200 cell surface glycoprotein receptor-like 4) (CD200 receptor-like 4) (CD200 cell surface glycoprotein receptor-like a) (CD200RLa) (Cell surface glycoprotein OX2 receptor 4) (Q6XJV4)
Organism: Mus musculus (Mouse)
Function: Involved in the recruitment or surface expression of the TYROBP receptor.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Sequence: MHALGRIPTLTLLIFINIFVSGSSCTDENQTIQNDSSSSLTQVNTTMSVQMDKKALLCCFSSPLINAVLITWIIKHRHLPSCTIAYNLDKKTNETSCLGRNITWASTPDHSPELQISAVALQHEGTYTCEIVTPEGNLEKVYDLQVLVPPEVTYFPGKNRTAVCEAMAGKPAAQISWTPDGDCVTKSESHSNGTVTVRSTCHWEQNNVSVVSCLVSHSTGNQSLSIELSQGTMTTPRSLLTILYVKMALLVIILLNVGFAFFQKRNFART
InterPro domains: - IPR013106: Immunoglobulin V-set domain (domain) [42-147]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [41-229]
- IPR013162: CD80-like, immunoglobulin C2-set (domain) [157-220]
- IPR007110: Immunoglobulin-like domain (domain) [8-229]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [26-237]
- IPR003599: Immunoglobulin domain subtype (domain) [44-147]
- IPR040012: Cell surface glycoprotein CD200 receptor (family) [1-266]
Interaction partners: - OX-2 membrane glycoprotein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0002682 (regulation of immune system process), GO:0051239 (regulation of multicellular organismal process), GO:0051240 (positive regulation of multicellular organismal process), GO:0002684 (positive regulation of immune system process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0002694 (regulation of leukocyte activation), GO:0002696 (positive regulation of leukocyte activation), GO:0042127 (regulation of cell population proliferation), GO:0050865 (regulation of cell activation), GO:0050867 (positive regulation of cell activation), GO:0008284 (positive regulation of cell population proliferation), GO:0051251 (positive regulation of lymphocyte activation), GO:0070665 (positive regulation of leukocyte proliferation), GO:0070663 (regulation of leukocyte proliferation), GO:0051249 (regulation of lymphocyte activation), GO:0032946 (positive regulation of mononuclear cell proliferation), GO:0050670 (regulation of lymphocyte proliferation), GO:0050864 (regulation of B cell activation), GO:0050871 (positive regulation of B cell activation), GO:0032944 (regulation of mononuclear cell proliferation), GO:0050671 (positive regulation of lymphocyte proliferation), GO:0030890 (positive regulation of B cell proliferation), GO:0030888 (regulation of B cell proliferation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098552 (side of membrane), GO:0009986 (cell surface), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0009897 (external side of plasma membrane), GO:0005886 (plasma membrane)