Protein: Probable mitochondrial phosphate carrier protein (Q9P7V8)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Transport of phosphate groups from the cytosol to the mitochondrial matrix.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}.
Sequence: MSTPLIPPAPPKKTLQLYTPQYYGLCTLGGLLACGTTHSAITPLDLIKCRKQVNPNIYPGNIAGFKTILSKEGLRGLYTGGMPTLIGYSLQGCGKYGFYELFKHKYSTLVGAQKAHEYRTSIYLAASASAELLADIMLCPMEAIKVRVQTSNPRFANTTREAWSKIVTNEGFGTLYRGLAPLWFRQIPYTMMKFASFERIVEALYTYIGKPKNMYSKAEKIGISFAGGYMAGVLCAIISHPADVMVSKLNSNKKAGEGAGAAAARIYKEIGFSGLWNGLGVRIVMIGTLTGAQWLIYDSFKIMCGFPATGA
InterPro domains: - IPR018108: Mitochondrial carrier protein, transmembrane region (repeat) [21-303]
- IPR023395: Mitochondrial carrier protein domain superfamily (homologous_superfamily) [12-306]
- IPR044677: Mitochondrial phosphate carrier protein SLC25A3/Pic2/Mir1-like (family) [12-310]
Interaction partners: - Cytochrome b-c1 complex subunit Rieske, mitochondrial
- ATP synthase subunit alpha
- Cytochrome b-c1 complex subunit 2, mitochondrial
- ATP synthase subunit beta, mitochondrial
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0005315 (inorganic phosphate transmembrane transporter activity), GO:0015291 (secondary active transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0042592 (homeostatic process), GO:0009987 (cellular process), GO:0048878 (chemical homeostasis), GO:0019725 (cellular homeostasis), GO:0055085 (transmembrane transport), GO:0051234 (establishment of localization), GO:0050801 (monoatomic ion homeostasis), GO:0055082 (intracellular chemical homeostasis), GO:0098660 (inorganic ion transmembrane transport), GO:0006810 (transport), GO:0098771 (inorganic ion homeostasis), GO:0034220 (monoatomic ion transmembrane transport), GO:0098655 (monoatomic cation transmembrane transport), GO:0098662 (inorganic cation transmembrane transport), GO:0055080 (monoatomic cation homeostasis), GO:0055070 (copper ion homeostasis), GO:0006873 (intracellular monoatomic ion homeostasis), GO:0006811 (monoatomic ion transport), GO:0015698 (inorganic anion transport), GO:0006878 (intracellular copper ion homeostasis), GO:0035435 (phosphate ion transmembrane transport), GO:0006812 (monoatomic cation transport), GO:0006817 (phosphate ion transport), GO:0035434 (copper ion transmembrane transport), GO:0030003 (intracellular monoatomic cation homeostasis), GO:0030001 (metal ion transport), GO:0000041 (transition metal ion transport), GO:0006825 (copper ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)