wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: AP complex subunit sigma (Q29RE3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. AP-4 is involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos, but may also recognize other types of sorting signal
Subcellular location: Endomembrane system; Peripheral membrane protein
Sequence: MIKFLLMVNKQGQTRLSKYYEAVDLGKRAALEADVVRGCLARRKEECSFVEYKDYKLVYRQYAALFIVVGVTENENELSIYELVHNFVEVLDKYFSRVSELDIMFNLDKVHIILDEMILNGHIVETNKNRILAPLLALDKMTES
InterPro domains: - IPR022775: AP complex, mu/sigma subunit (domain) [1-141]
- IPR016635: Adaptor protein complex, sigma subunit (family) [1-143]
- IPR011012: Longin-like domain superfamily (homologous_superfamily) [1-136]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0016043 (cellular component organization), GO:0048731 (system development), GO:0045229 (external encapsulating structure organization), GO:0043062 (extracellular structure organization), GO:0007399 (nervous system development), GO:0030198 (extracellular matrix organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0048471 (perinuclear region of cytoplasm), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Fibroblast growth factor (Q2LGG1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted
Sequence: MATAQRFLTSMCESSGRWTWTAVVLLGFLIGIVSSYPTSDRTNATSLEKRWEKLFSRSVLGISVEKSDLNWESDYLLGIKRVRRLYCNVGIGFHLQVLPDGRINGVHNENQYSLIEISAVERGVVSLYGVKSGLFVAMSSRGRLYGTRAFRDECKFKETLLPNNYNAYESSIYKGFYMALSKHGRLKRGYKASPAMTVTHFLPRL
InterPro domains: - IPR002209: Fibroblast growth factor family (family) [58-205]
- IPR008996: Cytokine IL1/FGF (homologous_superfamily) [79-204]
Interaction partners: - Fibroblast growth factor receptor 4
- Fibroblast growth factor receptor 2
- Fibroblast growth factor receptor 3
- Fibroblast growth factor receptor 1-A
- Platelet-derived growth factor receptor alpha
- receptor protein-tyrosine kinase
- Vascular endothelial growth factor receptor 2
- Vascular endothelial growth factor receptor kdr-like
- receptor protein-tyrosine kinase
- Vascular endothelial growth factor receptor 3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0070851 (growth factor receptor binding), GO:0005104 (fibroblast growth factor receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0007389 (pattern specification process), GO:0070121 (Kupffer's vesicle development), GO:0009799 (specification of symmetry), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0003002 (regionalization), GO:0009855 (determination of bilateral symmetry), GO:0030030 (cell projection organization), GO:0006996 (organelle organization), GO:0060972 (left/right pattern formation), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0030031 (cell projection assembly), GO:0007368 (determination of left/right symmetry), GO:0120036 (plasma membrane bounded cell projection organization), GO:0044782 (cilium organization), GO:0060271 (cilium assembly), GO:0120031 (plasma membrane bounded cell projection assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane), GO:0042383 (sarcolemma)
Protein: Sesquipedalian (Q0P3X0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane
Subcellular location: Early endosome. Recycling endosome. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, clathrin-coated vesicle
Sequence: MKIHKKILTHYLSCTSPVDKEGYLYKKRERNTTYLRRWFVLKGNLLFYQERPGDRNLLGVIVLEGCMVQACETDGQFCFSLVFTGPGLRTYRLAADDHPSQESWIAALFCASHIYLSMIVRDLERRYEEAKRDKGLCVSIQTSEVTSAPNTIMASWYTGQPYFIQGTSIVPRDGRSYSTSSIAPTYVPNRPSNFSLHAPPAQFKATNKRSPKLWPKRNAHVTPLNGPAPSHSEWPMMGFDPLEEFSKLHEHYGNEVRQLRADWLKKKRKETGYIEEDLIDLG
InterPro domains: - IPR001849: Pleckstrin homology domain (domain) [17-115]
- IPR045188: PH domain containing protein Boi1/Boi2-like (family) [2-276]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [12-135]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0009653 (anatomical structure morphogenesis), GO:0048523 (negative regulation of cellular process), GO:0050794 (regulation of cellular process), GO:0032989 (cellular component morphogenesis), GO:0000902 (cell morphogenesis), GO:0016043 (cellular component organization), GO:0060548 (negative regulation of cell death), GO:0010941 (regulation of cell death), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0030097 (hemopoiesis), GO:1901215 (negative regulation of neuron death), GO:0030030 (cell projection organization), GO:0006996 (organelle organization), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:0032990 (cell part morphogenesis), GO:0043066 (negative regulation of apoptotic process), GO:0042981 (regulation of apoptotic process), GO:0043524 (negative regulation of neuron apoptotic process), GO:0043523 (regulation of neuron apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle)
Protein: Ras-related protein Rab-35 (Q6DEJ0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, clathrin-coated vesicle. Endosome. Melanosome. Membrane, clathrin-coated pit
Sequence: MARDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVELNGEKVKLQIWDTAGQERFRTITSTYYRGTHGVVVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPNSKVVETNDAQKFAEQMGISLFETSAKENVNVEEMFNCITELVLRAKKESVAKQQQQQQNDVIKLKQNSKRKKKCC
InterPro domains: - IPR001806: Small GTPase (family) [1-201]
- IPR050305: Small GTPase superfamily, Rab (family) [3-201]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [1-201]
- IPR005225: Small GTP-binding domain (domain) [9-164]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0016043 (cellular component organization), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0022008 (neurogenesis), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0120036 (plasma membrane bounded cell projection organization), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0061564 (axon development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0005794 (Golgi apparatus), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0098791 (Golgi apparatus subcompartment), GO:0055037 (recycling endosome), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0005802 (trans-Golgi network), GO:0097708 (intracellular vesicle)
Protein: Organic solute carrier partner 1a (A0A8M2BLE8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MDVSHSIRERTIAENSLVILLQGLHGQVTTVDLRDESTARGRVINVDAFMNIRLENVLYRDRRGRKSSMDDLFITGRNVRYVHIPDQINIIETIEAQLSKIHRVRNFGAGGGRKEYSKKK
InterPro domains: - IPR047575: Sm domain (domain) [16-88]
- IPR001163: Sm domain, eukaryotic/archaea-type (domain) [19-84]
- IPR052840: U7 snRNA-associated Sm-like (family) [1-120]
- IPR010920: LSM domain superfamily (homologous_superfamily) [20-86]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0072359 (circulatory system development), GO:0007507 (heart development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Pyridoxal phosphate homeostasis protein (B1H1M3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'- phosphate (PLP), the active form of vitamin B6
Sequence: MWRVVMMSEEVGKKVQAVVERVNQAVSRRPKTLPCIPPRLVAVSKTKPPEMVVEAYKHGQRNFGENYVNELVEKASNPQILSSCPEIKWHFIGHLQKGNVNKLLGVPNLYMVETIDSVKLAEKVNSSWQKLRAANTHRLKIMVQINTSGEDSKHGLPPDETVNMVKHVVSQCPALDLAGLMTIGRYGYDLNDGPNPDFQLLLKCRVEVCESLKIPLEQVELSMGMSTDFEHAIEVGSTNIRVGSTIFGTREYPNTPSPSPEKKPKVVCEEAARKMDRLTVTEQ
InterPro domains: - IPR011078: Pyridoxal phosphate homeostasis protein (family) [9-257]
- IPR029066: PLP-binding barrel (homologous_superfamily) [5-255]
- IPR001608: Alanine racemase, N-terminal (domain) [38-250]
Interaction partners: - Purine nucleoside phosphorylase LACC1
- Erlin-2
- Pyridoxal kinase
- Pyridoxal kinase
- Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
- Small ribosomal subunit protein mS33
- 10 kDa heat shock protein, mitochondrial
- Sulfite oxidase, mitochondrial
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016830 (carbon-carbon lyase activity), GO:0016831 (carboxy-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048732 (gland development), GO:0061008 (hepaticobiliary system development), GO:0001889 (liver development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Amino acid transporter (A0A8N7UZX7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Multi-pass membrane protein
Sequence: MMPKHVEVRMHESHLEPIEARPLSKWGTICQKMRKNLLLTLTVMGVIMGAVSGMLLRVASPIDDNIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGLDAKSSGRLGSRAMIYYMTTTVIAAVLGVILVLLIHPGNPKLKENLGEGLENDEVSSLDAFFDLIRNLFPENLVQACFQQIQTVVKKVEVQPDLDDTNSTMSEYLSNATKPPPIFKDKKSLQFKSGMNVLGLIGFFIAFGICMGKMGEKARLMIDFFNILNEIVMKLVIMIMWYSPFGIACLICGKIISIKDLEVVARQLGMYMITVIVGLIIHGAIFLPCIYFAIVRKNPFSFFMGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGIDLDPGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRFRTSVNVVGDSYGAGIVYHLSKAELDALDAQHGKTDDIEMMTKTQSYYDDLKNHHENNSNQCVFAAQNTGLVDDCKVTLAATNGSTAEITVVEEEPWKND
InterPro domains: - IPR018107: Sodium:dicarboxylate symporter, conserved site (conserved_site) [73-400]
- IPR001991: Sodium:dicarboxylate symporter (family) [38-481]
- IPR036458: Sodium:dicarboxylate symporter superfamily (homologous_superfamily) [28-491]
- IPR050746: Dicarboxylate/Amino Acid:Cation Symporter (family) [18-518]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0042887 (amide transmembrane transporter activity), GO:0005342 (organic acid transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0046943 (carboxylic acid transmembrane transporter activity), GO:0005313 (L-glutamate transmembrane transporter activity), GO:0015171 (amino acid transmembrane transporter activity), GO:0015172 (acidic amino acid transmembrane transporter activity), GO:0015179 (L-amino acid transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0007610 (behavior), GO:0030537 (larval behavior), GO:0007626 (locomotory behavior), GO:0008345 (larval locomotory behavior)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098793 (presynapse), GO:0150034 (distal axon), GO:0044306 (neuron projection terminus), GO:0042995 (cell projection), GO:0030054 (cell junction), GO:0045202 (synapse), GO:0043679 (axon terminus), GO:0120025 (plasma membrane bounded cell projection), GO:0043005 (neuron projection), GO:0030424 (axon)
Protein: Tetraspanin (Q6DGC4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Multi-pass membrane protein
Sequence: MEGDCLSCIKYLMFIFNFFIFLGGSFLLGVGIWVLVDPTGFREIVAANSLLFTGVYAILIMGGMLFLLGFLGCCGAIRENKCLLLFFFMLILVIFLAELAVAILAFIFREHLTRDYFTKELKTHYQGTNSTDVFTSTWNAIMTTFNCCGVNSAEDFDDQSLFRRLNPSRIVPEVCCQRTDLMMSKEECLRGIMPIRNKGCYSAVVDYFETYIYMAGALAIVVLTIELFAMVFAMCLFRGIQ
InterPro domains: - IPR018503: Tetraspanin, conserved site (conserved_site) [62-84]
- IPR008952: Tetraspanin, EC2 domain superfamily (homologous_superfamily) [109-211]
- IPR000301: Tetraspanin, animals (family) [3-240]
- IPR018499: Tetraspanin/Peripherin (family) [9-238]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050793 (regulation of developmental process), GO:0051239 (regulation of multicellular organismal process), GO:2000026 (regulation of multicellular organismal development), GO:0022603 (regulation of anatomical structure morphogenesis), GO:1901342 (regulation of vasculature development), GO:0045765 (regulation of angiogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Opioid receptor, delta 1a (A3QJX7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane; Multi-pass membrane protein
Sequence: MEPSVIPGADIPDLYSINPFNVTFPDDVLSFVPDGRNYTEPNPVKSPAGIIIAISITALYSVICVVGLLGNILVMYGVVRYTKLKTATNIYIFNLALADALATSTLPFQSTKYLMNTWPFGELLCKVVIAIDYYNMFTSIFTLTMMSVDRYIAVCHPVRALEFRTPIKAKIINVCIWILSSAVGVPIMIMAVTRVTNQNTTVCMLKFPDPDWYWDTVTKICVFIFAFVVPVLVITICYGLMILRLKSVRLLSGSKEKDRNMRRITRMVLVVVAAFIICWTPIHIFIIVKTLVDINQKNPFVIASWHLCIALGYTNSSLNPVLYAFLDENFKRCFRDFCLPFRTRADQSNLNRARNATREPVSVCAPSDTGKKPV
InterPro domains: - IPR017452: GPCR, rhodopsin-like, 7TM (domain) [70-323]
- IPR001418: Opioid receptor (family) [80-334]
- IPR000276: G protein-coupled receptor, rhodopsin-like (family) [55-331]
Interaction partners: - Pro-opiomelanocortin protein
- Proenkephalin a
- Phosphatase and actin regulator 4A
- Zinc finger protein 131
- Proenkephalin-B
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0001653 (peptide receptor activity), GO:0008528 (G protein-coupled peptide receptor activity), GO:0004930 (G protein-coupled receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007186 (G protein-coupled receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: HCLS1-associated protein X-1 (Q6DHN8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MSVFDLFRGFFGVPGGHYREDGRRDPFFDGMIHEDDDDEDEDDFNRPHRDPFDDAFRFGFSFGPGGARFEEPQMFGQIFRDMEEMFAGLGRFDERHGFGPRGFPSIEAPPPQEGVEKGRSGTGSGNPIRDFMLKSPDRSPKDPEHREDSPPNHPHRRPFSKFNDIWKDGLLKPKGEDKREDGDLDSQVSSGGLDQILKDPAPSQPKTRSFFKSVSVTKVVRPDGTVEERRTVRDGEGNEETTVTISERPGGQDRPVLDQSGPLMPGGSDMQDDFSMFSKFFRGFRS
InterPro domains: - IPR017248: HS1-associating protein X-1 (family) [1-286]
Interaction partners: - Aquaporin-10b
- Pygopus homolog 2 (Drosophila)
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0051716 (cellular response to stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0006950 (response to stress), GO:0032989 (cellular component morphogenesis), GO:0000902 (cell morphogenesis), GO:0009611 (response to wounding), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0033554 (cellular response to stress), GO:0048731 (system development), GO:0016043 (cellular component organization), GO:0031099 (regeneration), GO:0022008 (neurogenesis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0032990 (cell part morphogenesis), GO:0031102 (neuron projection regeneration), GO:0048858 (cell projection morphogenesis), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0048678 (response to axon injury), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0031103 (axon regeneration), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0048812 (neuron projection morphogenesis), GO:0061564 (axon development), GO:0007409 (axonogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Carbonic anhydrase (A0A8M3ANQ1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Reversible hydration of carbon dioxide. Its role in saliva is unknown
Subcellular location: Secreted
Sequence: MEQLTLVLLFVTSLNFASAGVDGDYWTYSGELDQKHWAEKYHDCGGQQQSPIDIQRRKVRYSPRMQQLELTGYEDIRGSFLMKNNGHSVEIQLPSTMKITKGFPHQYTAVQMHLHWGGWDLEASGSEHTMDGIRYMAELHVVHYNSEKYPSFEEAKNKPDGLAVLAFFFEDGHFENTYYSDFISNLANIKYVGQSMSISNLNVLSMLSENLSHFYRYKGSLTTPPCFESVMWTVFDTPITLSHNQIRKLESTLMDHDNKTLWNDYRMAQPLNERVVESTFLPRLSKGGMCRQEEIEAKLKRIESLILSLDKKAVQASRPSSTGGKQPISPLVLYFPQKNVESFAVVNLTHPMELKSFTACMNVQIPPIRDLTVLSYSTSHDNELMISLGSEVGLWIGDEFVNLSFDLPSSDWTNYCLTWASHNGGAELWVNGVVGKERYIRTGYIIPAGGRLILGKDQDGFLGISVNDAFVGHMSDVNIWDYVLTEGEIVEQMSCDNGKVKGNVLSWGVTQLSLYGGVQLQGEQVCHRDNNNNRETEK
InterPro domains: - IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [332-519]
- IPR036398: Alpha carbonic anhydrase domain superfamily (homologous_superfamily) [22-288]
- IPR001759: Pentraxin domain (domain) [325-526]
- IPR023561: Carbonic anhydrase, alpha-class (family) [25-275]
- IPR018338: Carbonic anhydrase, alpha-class, conserved site (conserved_site) [126-142]
- IPR001148: Alpha carbonic anhydrase domain (domain) [24-280]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016835 (carbon-oxygen lyase activity), GO:0016836 (hydro-lyase activity), GO:0004089 (carbonate dehydratase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0007610 (behavior), GO:0007626 (locomotory behavior), GO:0036269 (swimming behavior)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009986 (cell surface)