wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Spermidine synthase (SPDSY) (EC 2.5.1.16) (Putrescine aminopropyltransferase) (P19623)
Organism: Homo sapiens (Human)
Function: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine.
Sequence: MEPGPDGPAASGPAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQVSKKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDAFDVIITDSSDPMGPAESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIPTYPSGQIGFMLCSKNPSTNFQEPVQPLTQQQVAQMQLKYYNSDVHRAAFVLPEFARKALNDVS
InterPro domains: - IPR035246: Spermidine synthase, tetramerisation domain (domain) [19-73]
- IPR030668: Spermidine/spermine synthase, eukaryotes (family) [9-302]
- IPR037163: Spermidine synthase, tetramerisation domain superfamily (homologous_superfamily) [1-74]
- IPR030374: Polyamine biosynthesis domain (domain) [18-253]
- IPR029063: S-adenosyl-L-methionine-dependent methyltransferase superfamily (homologous_superfamily) [16-302]
- IPR001045: Spermidine/spermine synthases (family) [14-301]
- IPR030373: Polyamine biosynthesis domain, conserved site (conserved_site) [97-110]
Interaction partners: - Ornithine decarboxylase
- Guanidino acid hydrolase, mitochondrial
- S-methyl-5'-thioadenosine phosphorylase
- Diamine acetyltransferase 1
- Spermine synthase
- Diamine oxidase [copper-containing]
- Thialysine N-epsilon-acetyltransferase
- Alpha-aminoadipic semialdehyde synthase, mitochondrial
- Antizyme inhibitor 2
- Arginase-2, mitochondrial
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0009308 (amine metabolic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0006576 (biogenic amine metabolic process), GO:0009309 (amine biosynthetic process), GO:0042401 (biogenic amine biosynthetic process), GO:0006595 (polyamine metabolic process), GO:0006596 (polyamine biosynthetic process), GO:0008216 (spermidine metabolic process), GO:0008295 (spermidine biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Uncharacterized protein DKFZp586B2022 (Q9Y423)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: KLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKRMS
InterPro domains: - IPR034960: Testin, LIM domain 3 (domain) [76-134]
- IPR001781: Zinc finger, LIM-type (domain) [14-130]
- IPR047120: Prickle/Espinas/Testin (family) [1-134]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0023056 (positive regulation of signaling), GO:0023057 (negative regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0010646 (regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0010647 (positive regulation of cell communication), GO:0033143 (regulation of intracellular steroid hormone receptor signaling pathway), GO:0033145 (positive regulation of intracellular steroid hormone receptor signaling pathway), GO:0033144 (negative regulation of intracellular steroid hormone receptor signaling pathway), GO:0033146 (regulation of intracellular estrogen receptor signaling pathway), GO:0033146 (regulation of intracellular estrogen receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: N-acetylneuraminic acid outer membrane channel protein NanC (N-acetylneuraminic acid-inducible outer membrane channel) (NanR-regulated channel) (Porin NanC) (P69856)
Organism: Escherichia coli (strain K12)
Function: Outer membrane channel protein allowing the entry of N-acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria (Probable). NanC proteins form high-conductance channels which are open at low membrane potentials and which have a weak anion selectivity.
Subcellular location: Cell outer membrane {ECO:0000269|PubMed:19796645}; Multi-pass membrane protein {ECO:0000269|PubMed:19796645}.
Sequence: MKKAKILSGVLLLCFSSPLISQAATLDVRGGYRSGSHAYETRLKVSEGWQNGWWASMESNTWNTIHDNKKENAALNDVQVEVNYAIKLDDQWTVRPGMLTHFSSNGTRYGPYVKLSWDATKDLNFGIRYRYDWKAYRQQDLSGDMSRDNVHRWDGYVTYHINSDFTFAWQTTLYSKQNDYRYANHKKWATENAFVLQYHMTPDITPYIEYDYLDRQGVYNGRDNLSENSYRIGVSFKL
InterPro domains: - IPR009331: Oligogalacturonate-specific porin (family) [1-238]
- IPR053713: Bacterial Outer Membrane Channel Superfamily (homologous_superfamily) [25-238]
Interaction partners: - N-acetylneuraminate epimerase
- Sialic acid transporter NanT
- N-acetylneuraminate lyase
- Probable 9-O-acetyl-N-acetylneuraminic acid deacetylase
- Outer membrane porin G
- Sialic acid transporter NanX
- HTH-type transcriptional repressor NanR
- Outer membrane porin F
- Outer membrane protein A
- N-acetylneuraminate anomerase NanQ
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015267 (channel activity), GO:0022829 (wide pore channel activity), GO:0015288 (porin activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0034219 (carbohydrate transmembrane transport), GO:0006810 (transport), GO:0015749 (monosaccharide transmembrane transport), GO:0071702 (organic substance transport), GO:0008645 (hexose transmembrane transport), GO:0008643 (carbohydrate transport), GO:1904659 (glucose transmembrane transport), GO:0046323 (glucose import)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0031975 (envelope), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030312 (external encapsulating structure), GO:0009279 (cell outer membrane), GO:0019867 (outer membrane), GO:0030313 (cell envelope)
Protein: Female-specific lacrimal gland protein (Female-specific LG protein) (Q99MG7)
Organism: Mesocricetus auratus (Golden hamster)
Function: Not known
Subcellular location: Secreted {ECO:0000269|PubMed:15950295, ECO:0000269|PubMed:7887957}. Note=Secreted by the lacrimal gland into tears. {ECO:0000269|PubMed:15950295, ECO:0000269|PubMed:7887957}.
Sequence: MVKFLLLALALGVSCAHYQNLEVSPSEVDGKWYSLYIAADNKEKVSEGGPLRAYIKNVECIDECQTLKITFYTKVEGVCQEHTIVGRKGEDGKYITDFSGQNYFHIVEKSDDTMTFHNVNVDDSGKTNVILVVGRGESSSIEQKQRFEKTAEEYDIPKENIEDLVPTDNCDQ
InterPro domains: - IPR012674: Calycin (homologous_superfamily) [17-171]
- IPR000566: Lipocalin/cytosolic fatty-acid binding domain (domain) [30-168]
- IPR022272: Lipocalin family conserved site (conserved_site) [22-35]
- IPR002345: Lipocalin (family) [5-170]
- IPR002448: Lipocalin, OBP-like (family) [28-171]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:0043167 (ion binding), GO:0008289 (lipid binding), GO:0043168 (anion binding), GO:0005504 (fatty acid binding), GO:0043177 (organic acid binding), GO:0031406 (carboxylic acid binding), GO:0033293 (monocarboxylic acid binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0014070 (response to organic cyclic compound), GO:0032355 (response to estradiol), GO:1901701 (cellular response to oxygen-containing compound), GO:0071310 (cellular response to organic substance), GO:0033993 (response to lipid), GO:0071392 (cellular response to estradiol stimulus), GO:0071407 (cellular response to organic cyclic compound), GO:0071396 (cellular response to lipid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Cold shock protein CspA (CSP-A) (7.4 kDa cold shock protein) (CS7.4) (P0A9X9)
Organism: Escherichia coli (strain K12)
Function: Binds to and stimulates the transcription of the CCAAT-containing, cold-shock-inducible promoters of the H-NS and GyrA proteins. Binds also to the inverted repeat 5'-ATTGG-3'.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:2404279}.
Sequence: MSGKMTGIVKWFNADKGFGFITPDDGSKDVFVHFSAIQNDGYKSLDEGQKVSFTIESGAKGPAAGNVTSL
InterPro domains: - IPR012156: Cold shock, CspA (family) [1-70]
- IPR011129: Cold-shock domain (domain) [6-70]
- IPR050181: Cold shock domain-containing protein (family) [2-69]
- IPR019844: Cold-shock domain, conserved site (conserved_site) [18-37]
- IPR002059: Cold-shock protein Csp, DNA-binding (domain) [4-69]
- IPR012340: Nucleic acid-binding, OB-fold (homologous_superfamily) [2-70]
Interaction partners: - Large ribosomal subunit protein bL25
- Small ribosomal subunit protein bS21
- Ribonuclease E
- Small ribosomal subunit protein uS15
- Elongation factor Tu 1
- Uncharacterized protein YaeQ
- Small ribosomal subunit protein uS12
- Large ribosomal subunit protein bL31
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein bS20
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0006950 (response to stress), GO:0009628 (response to abiotic stimulus), GO:0009266 (response to temperature stimulus), GO:0009409 (response to cold)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Obg like ATPase 1 (C9JTK6)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MPPKKGGDGIKPPPIIGRFGTSLKIGIVGLPNVGKSTFFNVLTNSQASAENFPFCTIDPNESRVPVPDERFDFLCQYHKPASKIPAFLNVVDIAGLVKGAHNGQGLGNAFLSHISA
InterPro domains: - IPR031167: OBG-type guanine nucleotide-binding (G) domain (domain) [23-116]
- IPR006073: GTP binding domain (domain) [24-116]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [1-116]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity), GO:0017111 (ribonucleoside triphosphate phosphatase activity), GO:0003924 (GTPase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0044248 (cellular catabolic process), GO:0009057 (macromolecule catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0006508 (proteolysis), GO:0044265 (cellular macromolecule catabolic process), GO:0030163 (protein catabolic process), GO:0043632 (modification-dependent macromolecule catabolic process), GO:0010498 (proteasomal protein catabolic process), GO:0051603 (proteolysis involved in protein catabolic process), GO:0019941 (modification-dependent protein catabolic process), GO:0043161 (proteasome-mediated ubiquitin-dependent protein catabolic process), GO:0006511 (ubiquitin-dependent protein catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Protein channel (Q59LZ5)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Subcellular location: Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004572}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004572}.
Sequence: MSSDNFFIKNRTAIIVTALTAFSAAGAYYYYTQQQSTGGSNSSSKSNKSSSEEGNTSTSSSSSKKKKKSKKSKGSATPEPTNSTSSSTTTTTTTTTTSSSDSKSTSSKKIKYPINSEGLPELTSDIISKLSETEKEEWAMQLKEDGNQEFKNKNFKKAIEFYSAALELKQDPIYYSNRSACYAALDDHENVIKDTTEAINLKPDYTKCILRRATSFEVLEKYEDAMFDLTALTIYGGFSNKSIEQVLERVLRKHSIKIVESKPKKLILPSAATIGSFFGAFVEETEPEGINESHENEGVKALYTALQKINANTQNGYEEADELISKAVTELESAIESATELKPVLAIALEYLAAFQFLKNDPVSAAESIEKAISLKPRPRAYVFRALINADKSSYEAALKDFKTAEELDDKCPDIFYHLGQLFYLTGDLTNAEINFNKAKELHPDNVYAYIQLACITYKNGQIELANEKFTEAKLKFPTSPEVPNYYGEILADKGDIQGACKQFEIASRLQEKLDRFSVGALPLINEATVISRESLEKIGEAEELLTKACALDPKSELARISLAQIKLQKDEVDDAIVLFEESSDLARSIEEKIQATSFAEATKMQKRIKNDPILNNKIAELMRQSGAM
InterPro domains: - IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [125-622]
- IPR019734: Tetratricopeptide repeat (repeat) [139-590]
Interaction partners: - Mitochondrial import receptor subunit TOM20
- Tom22p
- Translocase of outer membrane 40 kDa subunit
- Mitochondrial outer membrane protein porin
- Tom7p
- Mitochondrial import inner membrane translocase subunit TIM17
- Mitochondrial import inner membrane translocase subunit TIM44
- Mitochondrial import inner membrane translocase subunit TIM23
- Mitochondrial import inner membrane translocase subunit TIM21
- Mitochondrial import inner membrane translocase subunit TIM8
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0033218 (amide binding), GO:0042277 (peptide binding), GO:0005048 (signal sequence binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0071840 (cellular component organization or biogenesis), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0016043 (cellular component organization), GO:0046907 (intracellular transport), GO:0045184 (establishment of protein localization), GO:0006810 (transport), GO:0006839 (mitochondrial transport), GO:0071702 (organic substance transport), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0008104 (protein localization), GO:0006996 (organelle organization), GO:0015031 (protein transport), GO:0072594 (establishment of protein localization to organelle), GO:0072655 (establishment of protein localization to mitochondrion), GO:0007005 (mitochondrion organization), GO:0033365 (protein localization to organelle), GO:0006605 (protein targeting), GO:0006626 (protein targeting to mitochondrion), GO:0070585 (protein localization to mitochondrion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Ciliary microtubule associated protein 1A (Outer dense fiber of sperm tails protein 3) (Outer dense fiber protein 3) (Sperm tail protein SHIPPO 1) (Transcript induced in spermiogenesis protein 50) (Q96PU9)
Organism: Homo sapiens (Human)
Function: Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q920N1}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q920N1}. Note=Expressed in the cytoplasmic lobe of spermatids. {ECO:0000250|UniProtKB:Q920N1}.
Sequence: MTEEVWMGTWRPHRPRGPIMALYSSPGPKYLIPPTTGFMKHTPTKLRAPAYSFRGAPMLLAENCSPGPRYNVNPKILRTGKDLGPAYSILGRYQTKTMLTPGPGDYFPEKSTKYVFDSAPSHSISARTKAFRVDSTPGPAAYMLPMVMGPNTVGKASQPSFSIKGRSKLGGFSDDLHKTPGPAAYRQTDVRVTKFKAPQYTMAARVEPPGDKTLKPGPGAHSPEKVTLTKPCAPVVTFGIKHSDYMTPLLVDVE
InterPro domains: - IPR051291: Ciliary Microtubule Associated (family) [9-240]
- IPR010736: Sperm-tail PG-rich repeat (repeat) [100-243]
Interaction partners: - Outer dense fiber protein 4
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009893 (positive regulation of metabolic process), GO:0065009 (regulation of molecular function), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0050790 (regulation of catalytic activity), GO:0031323 (regulation of cellular metabolic process), GO:0044093 (positive regulation of molecular function), GO:0031325 (positive regulation of cellular metabolic process), GO:0010562 (positive regulation of phosphorus metabolic process), GO:0051338 (regulation of transferase activity), GO:0043085 (positive regulation of catalytic activity), GO:0051174 (regulation of phosphorus metabolic process), GO:0045937 (positive regulation of phosphate metabolic process), GO:0043549 (regulation of kinase activity), GO:0051347 (positive regulation of transferase activity), GO:0019220 (regulation of phosphate metabolic process), GO:0042325 (regulation of phosphorylation), GO:0033674 (positive regulation of kinase activity), GO:0042327 (positive regulation of phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0005881 (cytoplasmic microtubule), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0099513 (polymeric cytoskeletal fiber), GO:0005874 (microtubule), GO:0015630 (microtubule cytoskeleton)
Protein: Sad1 and UNC84 domain containing 1 (H0Y742)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Nucleus inner membrane {ECO:0000256|ARBA:ARBA00004540}.
Sequence: GDVGAAAATAHNGFSCSNCSMLSERKDVLTAHPAAPGPVSRVYSRDRNQKCGASFYVNRILWLARYTASSFSSFLVQLFQVVLMKLSYESENYKLKTHESKDCESESYKSKSHESKAHASYYGRMNVREVLREDGHLSVNGEALCYFLLQILRRIGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNICKFLVLLIPLFLLLAGLSLRGQGNFFSFLPVLNWASMHRTQRVDDPQDVFKPTTSRLKQPLQGDSEAFPWHWMSGVEQQVASLSGQCHHHGENLRELTTLLQKLQARVDQMEGGAAGPSASVRDAVGQPPRETDFMAFHQEHEVRMSHLEDILGKLREKSEAIQKELEQTKQKTISAVGEQLLPTVEHLQLELDQLKSELSSWRHVKTGCETVDAVQERVDVQVREMVKLLFSEDQQGGSLEQLLQRFSSQFVSKGDLQTMLRDLQLQILRNVTHHVSVTKQLPTSEAVVSAVSEAGASGITEAQARAIVNSALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALMSLFGIPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMMIHPAAFTLEHIPKTLSPTGNISSAPKDFAVYGLENEYQEEGQLLGQFTYDQDGESLQMFQALKRPDDTAFQIVELRIFSNWGHPEYTCLYRFRVHGEPVK
InterPro domains: - IPR032680: SUN domain-containing protein 1, N-terminal (domain) [6-216]
- IPR045119: SUN domain-containing protein 1-5 (family) [7-708]
- IPR012919: SUN domain (domain) [547-709]
- IPR040994: SUN coiled coil domain 2 (domain) [472-530]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051641 (cellular localization), GO:0071840 (cellular component organization or biogenesis), GO:0051651 (maintenance of location in cell), GO:0051235 (maintenance of location), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0016043 (cellular component organization), GO:0045185 (maintenance of protein location), GO:0032507 (maintenance of protein location in cell), GO:0072595 (maintenance of protein localization in organelle), GO:0008104 (protein localization), GO:0006996 (organelle organization), GO:0033365 (protein localization to organelle), GO:0006997 (nucleus organization), GO:0051457 (maintenance of protein location in nucleus), GO:0034504 (protein localization to nucleus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005635 (nuclear envelope), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031965 (nuclear membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)