Protein: Cullin-associated NEDD8-dissociated protein 1, C-terminal part (Cullin-associated and neddylation-dissociated protein 1, C-terminal part) (Q5BAH2)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor when interacting with candA-N (By similarity).
Subcellular location: Nucleus {ECO:0000269|PubMed:21119001}.
Sequence: MSSDAMSDYSHDDEHDPQTDELRETALVTLEALISSCSSQMQSYLPNTINSALRFLKYDPNVADMGEDEEMSGTQDDGSEDDVTEEPDLEDDDFEDFEEEGGYSDIDDMSWKVRRCAAKLLYAVISTYGRGRALDDTSLYQQIAPAIVARFNKEREESVKLELVSTMDALVRKTAEGSMIMTSSGFLESVGSGSKISRKRRRQDSDASMIDFEPSMGTSSAAGTPLAAPSSPQSGPQSELANALPVIVRSLVTMWKQASIHLKQAIIILLKSLALVRYGGLADHLQQIEDPIADVLKSSLSGAPSASIGISASAGTLQIETLSLISAISETHASDALLPFLIALIPGVIVAVNDKNYKVSSEALAAVEQIVKALTPPRVTTASQDLIFQLEKLYDVSHSRITDTSADLEVRQRAIHVLGVLLARTSDEQGSAFLSFEKRSKGLVTLVDRLKNETTRLSAVRAIDDVAVLCSRKDDVDSNWVREVTAELGAQLRKSDRVLRSASLETLRSLSMNPNTRAHYDGETMKNLEECLIPLISVEDVHLLAPSLIIIAKLVPGNAQLLVNDGLVSAICSIVRTSLAGTVLKALLLLVKVIGEEGSGLTLMQNLLQDVGVNGDTSVVGRSIGTLLVHGGSNVGVRMEDFLSELQKTQDPQRQCLALAILGESALRLGASCSLTPNVFIPHFNSKSEKVRLASATALGNAAAGNVKAYLPTILGGLEKSDPQSYLLLHSVKELLQHPEMVRRDVAPSALKLWQALLVVSKEEDNRAMGAECVGRLALLDPPAYIPQFQEYLANGDAGIRSIVVSAFRFTLSDSRDVFNDVLRPLIVPLLVNMLSDRDLGNHRLALTTLNSAIHNKLALILPHLGELLPAVLGDTQIKPELIREVQMGPFKHKVDDGLELRKSAYETVYAALDTSFSLSHITELYSRILAGIDDEQDIRTICNLMTSKLITLAPEETQRHLDALSERYTAILNFKPKENAVKQEIEKAQEASTGVLKITRELSKAFPNAETMGDHHKWKAYMEMVRAQFGTQLSNLESEF
InterPro domains: - IPR016024: Armadillo-type fold (homologous_superfamily) [19-1030]
- IPR011989: Armadillo-like helical (homologous_superfamily) [4-1030]
- IPR013932: TATA-binding protein interacting (TIP20) (domain) [860-1026]
- IPR039852: Cullin-associated NEDD8-dissociated protein 1/2 (family) [9-1029]
Interaction partners: - Cullin-associated NEDD8-dissociated protein 1, N-terminal part
- RING-box protein 1
- Ubiquitin ligase subunit CulD, putative
- JmjC domain-containing histone demethylation protein 1
- Cullin-1
- SCF ubiquitin ligase subunit CulC, putative
- DNA damage-binding protein 1
- Ubiquitin-like domain-containing protein
- SCF E3 ubiquitin ligase complex F-box protein grrA
- E3 ubiquitin ligase complex SCF subunit sconC
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0019954 (asexual reproduction), GO:0043934 (sporulation), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0030435 (sporulation resulting in formation of a cellular spore), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0030436 (asexual sporulation), GO:0048315 (conidium formation), GO:0061794 (conidium development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)