Protein: CLIP domain-containing serine protease (EC 3.4.21.-) (Q9VA44)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Secreted {ECO:0000256|RuleBase:RU366078}.
Sequence: MKVIAAVLLCLLIIRTAHGQYVSCRNPNQRTGYCVNIPLCVPLNSVLAKSNPTDSEMRFIRESRCLVSDQSDLPFVCCTPDTDYNTTRARPNDEVIHSTLLPDRSICGGDIAYNQITKGNETVLTEFAWMVLLEYRPHDGQQLRTYCAGSLINNRYVVTAAHCVSAATRARKGDVSFRVSVRLGEHNTSAVVDCLNGRCLPEPVQIAVEEIRIHESFGTRLFWNDIALIRLAREVAYSPSIRPVCLPSTVGLQNWQSGQAFTVAGWGRTLTSESSPVKMKLRVTYVEPGLCRRKYASIVVLGDSHLCAEGRSRGDSCDGDSGGPLMAFHEGVWVLGGIVSFGLNCGSRFWPAVYTNVLSYETWITQNIRP
InterPro domains: - IPR001314: Peptidase S1A, chymotrypsin family (family) [148-326]
- IPR043504: Peptidase S1, PA clan, chymotrypsin-like fold (homologous_superfamily) [116-365]
- IPR038565: Proteinase, regulatory CLIP domain superfamily (homologous_superfamily) [15-78]
- IPR001254: Serine proteases, trypsin domain (domain) [106-369]
- IPR018114: Serine proteases, trypsin family, histidine active site (active_site) [158-163]
- IPR033116: Serine proteases, trypsin family, serine active site (active_site) [315-326]
- IPR022700: Proteinase, regulatory CLIP domain (domain) [23-79]
- IPR009003: Peptidase S1, PA clan (homologous_superfamily) [106-369]
- IPR051487: Serine/Threonine Proteases with Immune and Developmental Roles (family) [28-369]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0017171 (serine hydrolase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0048584 (positive regulation of response to stimulus), GO:0019222 (regulation of metabolic process), GO:0009607 (response to biotic stimulus), GO:0002684 (positive regulation of immune system process), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0009893 (positive regulation of metabolic process), GO:0002682 (regulation of immune system process), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0051707 (response to other organism), GO:0044238 (primary metabolic process), GO:0048522 (positive regulation of cellular process), GO:0002831 (regulation of response to biotic stimulus), GO:0032103 (positive regulation of response to external stimulus), GO:0050776 (regulation of immune response), GO:1901564 (organonitrogen compound metabolic process), GO:0043207 (response to external biotic stimulus), GO:0031325 (positive regulation of cellular metabolic process), GO:0002833 (positive regulation of response to biotic stimulus), GO:0080134 (regulation of response to stress), GO:0019538 (protein metabolic process), GO:0006952 (defense response), GO:0050778 (positive regulation of immune response), GO:0032101 (regulation of response to external stimulus), GO:0043455 (regulation of secondary metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0031349 (positive regulation of defense response), GO:0043170 (macromolecule metabolic process), GO:0009620 (response to fungus), GO:0098542 (defense response to other organism), GO:0031347 (regulation of defense response), GO:0045089 (positive regulation of innate immune response), GO:0045088 (regulation of innate immune response), GO:0050832 (defense response to fungus), GO:0051604 (protein maturation), GO:0035007 (regulation of melanization defense response), GO:0010467 (gene expression), GO:0072376 (protein activation cascade), GO:0160032 (Toll receptor ligand protein activation cascade)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)