Protein: Transient receptor potential cation channel, subfamily C, member 7 (A0A8I6GIF7)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MLGSNTFKNMQRRHTTLREKGRRQAIRGPAYMFNEKGTSLTPEEERFLDSAEYGNIPVVRKMLEESKTLNFNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARVGDALLLAISKGYVRIVEAILSHPAFAQGQRLTLSPLEQELRDDDFYAYDEDGTRFSHDITPIILAAHCQEYEIVHILLLKGARIERPHDYFCKCNECTEKQRKDSFSHSRSRMNAYKGLASAAYLSLSSEDPVLTALELSNELARLANIETEFKFVAHPNCQQQLLTMWYENLSGLRQQSIAVKFLAVFGVSIGLPFLAIAYWIAPCSKLGRTLRSPFMKFVAHAVSFTIFLGLLVVNASDRFEGVKTLPNETFTDYPKQIFRVKTTQFSWTEMLIMKWVLGMIWSECKEIWEEGPREYVLHLWNLLDFGMLSVFVASFTARFMAFLKASEAQLYVDQYVQDVTLHNVSLPPEVAYFTYARDKWWPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLYSYYRGAKYNPAFTTVEESFKTLFWSIFGLSEVISVVLKYDHKFIENIGYVLYGVYNVTMVVVLLNMLIAMINNSYQEIEEDADVEWKFARAKLWLSYFDEGRTLPAPFNLVPSPKSFYYLIMRIKMCLIKLCKSKAKRCENDLEMGMLNSKFRKTRYQAGMRNSENLTANSTFSKPTRYQKIMKRLIKRYVLKAQVDRENDEVNEGELKEIKQDISSLRYELLEEKSQATGELADLIQQLSEKFGKNLNKDHLRVNKGKDI
InterPro domains: - IPR013555: Transient receptor ion channel domain (domain) [198-260]
- IPR005463: Transient receptor potential channel, canonical 7 (family) [1-801]
- IPR036770: Ankyrin repeat-containing domain superfamily (homologous_superfamily) [31-220]
- IPR002110: Ankyrin repeat (repeat) [42-192]
- IPR002153: Transient receptor potential channel, canonical (family) [260-782]
- IPR005821: Ion transport domain (domain) [351-622]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0015267 (channel activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0005261 (monoatomic cation channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0042221 (response to chemical), GO:0055085 (transmembrane transport), GO:0051240 (positive regulation of multicellular organismal process), GO:0051234 (establishment of localization), GO:0051239 (regulation of multicellular organismal process), GO:0050793 (regulation of developmental process), GO:0065008 (regulation of biological quality), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0007568 (aging), GO:0051094 (positive regulation of developmental process), GO:0048522 (positive regulation of cellular process), GO:0045597 (positive regulation of cell differentiation), GO:0001666 (response to hypoxia), GO:0050773 (regulation of dendrite development), GO:0006979 (response to oxidative stress), GO:0098660 (inorganic ion transmembrane transport), GO:0048731 (system development), GO:0070482 (response to oxygen levels), GO:0048513 (animal organ development), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0035295 (tube development), GO:2000026 (regulation of multicellular organismal development), GO:0007204 (positive regulation of cytosolic calcium ion concentration), GO:1901698 (response to nitrogen compound), GO:0060322 (head development), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0030900 (forebrain development), GO:0006810 (transport), GO:0051962 (positive regulation of nervous system development), GO:0034599 (cellular response to oxidative stress), GO:0071456 (cellular response to hypoxia), GO:0098655 (monoatomic cation transmembrane transport), GO:0071453 (cellular response to oxygen levels), GO:0062197 (cellular response to chemical stress), GO:0060284 (regulation of cell development), GO:0010720 (positive regulation of cell development), GO:0071702 (organic substance transport), GO:0050769 (positive regulation of neurogenesis), GO:0051960 (regulation of nervous system development), GO:0006811 (monoatomic ion transport), GO:0007420 (brain development), GO:0098662 (inorganic cation transmembrane transport), GO:0007399 (nervous system development), GO:0010243 (response to organonitrogen compound), GO:0036293 (response to decreased oxygen levels), GO:0007417 (central nervous system development), GO:0014070 (response to organic cyclic compound), GO:1901701 (cellular response to oxygen-containing compound), GO:0006812 (monoatomic cation transport), GO:0036294 (cellular response to decreased oxygen levels), GO:0006812 (monoatomic cation transport), GO:0036294 (cellular response to decreased oxygen levels), GO:0006816 (calcium ion transport), GO:0050767 (regulation of neurogenesis), GO:0030001 (metal ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0005622 (intracellular anatomical structure), GO:0048471 (perinuclear region of cytoplasm), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005801 (cis-Golgi network)