Protein: Tsr1p (Q5A346)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Sequence: MANSHRNTLKHDHKPFKSKHATKGQIKARIKGKVEKSSNSSGGSKSSKVVSKLERKNLSKQQRDNKILETKLTKKLFEGNSGAEKIVTIITLTNDLSAVDIANRLFNEQEDTSNESITRFDFGYPSVTNINIAKFKTNLKVIIPKQNNMISILDAAQVSDFVLLGISATEEIGENSFGETVLRALIAQGISTTIGVLPNIVSAYPKRNLQLDVKQSLQSFYHHFFPSRDGSSNRGSGTDSGGNKLYSLELDSDNSNCLRIICQKFPQSITWRDSRGWLVADKVEIFNPNGMPVENQQQMMVVEGMVRGVGFNVNRLVHLPGLGDFQLHKLEKLARKARGNSSRNHRGGMDIDTGNDGDAEETFLPNEQQESLDELNPDEGIDMGTMEDDDDFLNNDNFGVRSEGKIYFDNGNSNGTSSSSTGKKLVPRGTSEYQGRWFVDDVLDEDASDLEEQREGEGEEEEDANIVDDDMMVEDNMEADDITDSIHDSEMMHVDLSPEEESRQLEEYRSLAKDDLEFPDEIELHPNESAIERLKGFRGVKSLGNCDWDYDEYDPEAPSILKRLFQVSNYKATKNKVNKQFIKQTEITAGNRVRLYIIIPPGASNNVSSVIGSCSSVPFPVYELLEHEHKLGVCNFSFEAWQDYEKPIINKEQIIVQYGPRRQIIQPLYNQANNNPNNVHKLENFVHHNQGGGGAIIATAITPVLFTNSPTLFFKIHPDADDSSNSNGGSVEFVGKGTYLGSDAKRIMVQRVVLTGHPIKIHKRVVTIRYMFFNREDINYFKAVSLFTKNSGRVGFIKESLGTHGYFKANFDGKLTSQDVVAMSLYKRSWPEVSTAWNKFNY
InterPro domains: - IPR030387: Bms1/Tsr1-type G domain (domain) [83-267]
- IPR007034: Ribosome biogenesis protein BMS1/TSR1, C-terminal (domain) [521-831]
- IPR012948: AARP2CN (domain) [253-337]
- IPR039761: Ribosome biogenesis protein Bms1/Tsr1 (family) [9-840]
Interaction partners: - Serine/threonine-protein kinase RIO2
- 20S-pre-rRNA D-site endonuclease NOB1
- Ltv1p
- SnoRNA-binding rRNA-processing protein
- mRNA-binding protein
- rRNA adenine N
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein eS6
- Small ribosomal subunit protein eS7
- Small ribosomal subunit protein uS4
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0043021 (ribonucleoprotein complex binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044237 (cellular metabolic process), GO:0044238 (primary metabolic process), GO:0044085 (cellular component biogenesis), GO:0046483 (heterocycle metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0042274 (ribosomal small subunit biogenesis), GO:0016070 (RNA metabolic process), GO:0090305 (nucleic acid phosphodiester bond hydrolysis), GO:0006396 (RNA processing), GO:0042254 (ribosome biogenesis), GO:0090501 (RNA phosphodiester bond hydrolysis), GO:0034470 (ncRNA processing), GO:0031123 (RNA 3'-end processing), GO:0030490 (maturation of SSU-rRNA), GO:0006364 (rRNA processing), GO:0034660 (ncRNA metabolic process), GO:0000469 (cleavage involved in rRNA processing), GO:0031125 (rRNA 3'-end processing), GO:0000462 (maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)), GO:0090502 (RNA phosphodiester bond hydrolysis, endonucleolytic), GO:0016072 (rRNA metabolic process), GO:0043628 (regulatory ncRNA 3'-end processing), GO:0000478 (endonucleolytic cleavage involved in rRNA processing), GO:0000479 (endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA))
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)