Protein: ABC transporter, white homologue (Q9EPG9)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MACLMAAFSVGTAMNASNYSAAMTEPKSVCVSVDEVVSSNVDELETDLLNGHLKKVDNNFTEAQRFSSLPRRAAVNIEFKDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGMPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQERDEGRREMVKEILTALGLLPCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIVCTIHQPSAKLFELFDQLYVLSQGQCVYRGKVSNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDYKRELGGDGDVNPFLWHRPAEEDSASMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMSVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTMTSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIAETCHFQKSEAILRELDVENAKLYLDFIVLGIFFISLRLIAYFVLRYKIRAER
InterPro domains: - IPR013525: ABC-2 type transporter, transmembrane domain (domain) [391-600]
- IPR005284: Pigment precursor permease/Protein ATP-binding cassette sub-family G (family) [61-665]
- IPR017871: ABC transporter-like, conserved site (conserved_site) [217-231]
- IPR003593: AAA+ ATPase domain (domain) [110-293]
- IPR043926: ABC transporter family G domain (domain) [274-332]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [74-340]
- IPR003439: ABC transporter-like, ATP-binding domain (domain) [77-317]
- IPR050352: ATP-binding cassette subfamily G transporters (family) [57-654]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140657 (ATP-dependent activity), GO:0005215 (transporter activity), GO:0042626 (ATPase-coupled transmembrane transporter activity), GO:0022857 (transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0015399 (primary active transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0065008 (regulation of biological quality), GO:0023056 (positive regulation of signaling), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0051234 (establishment of localization), GO:0023051 (regulation of signaling), GO:0051050 (positive regulation of transport), GO:0033036 (macromolecule localization), GO:0048522 (positive regulation of cellular process), GO:0010876 (lipid localization), GO:1903530 (regulation of secretion by cell), GO:1903829 (positive regulation of protein localization), GO:0051049 (regulation of transport), GO:0051047 (positive regulation of secretion), GO:0046887 (positive regulation of hormone secretion), GO:0010646 (regulation of cell communication), GO:0060341 (regulation of cellular localization), GO:0006810 (transport), GO:0010647 (positive regulation of cell communication), GO:0051130 (positive regulation of cellular component organization), GO:0051222 (positive regulation of protein transport), GO:0010817 (regulation of hormone levels), GO:0051128 (regulation of cellular component organization), GO:0046883 (regulation of hormone secretion), GO:1903532 (positive regulation of secretion by cell), GO:0006869 (lipid transport), GO:0051223 (regulation of protein transport), GO:0090276 (regulation of peptide hormone secretion), GO:0090087 (regulation of peptide transport), GO:1904951 (positive regulation of establishment of protein localization), GO:0070201 (regulation of establishment of protein localization), GO:0002793 (positive regulation of peptide secretion), GO:0033043 (regulation of organelle organization), GO:0071702 (organic substance transport), GO:0051046 (regulation of secretion), GO:0090277 (positive regulation of peptide hormone secretion), GO:0032880 (regulation of protein localization), GO:0050708 (regulation of protein secretion), GO:0010638 (positive regulation of organelle organization), GO:0050714 (positive regulation of protein secretion), GO:0015850 (organic hydroxy compound transport), GO:0002791 (regulation of peptide secretion), GO:0032024 (positive regulation of insulin secretion), GO:0035774 (positive regulation of insulin secretion involved in cellular response to glucose stimulus), GO:0061178 (regulation of insulin secretion involved in cellular response to glucose stimulus), GO:0050796 (regulation of insulin secretion), GO:0015918 (sterol transport), GO:0030301 (cholesterol transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098552 (side of membrane), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0009986 (cell surface), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0012505 (endomembrane system), GO:0009897 (external side of plasma membrane), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0055037 (recycling endosome), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)