Protein: MIF4G domain-containing protein (SMG-3) (G5EDT8)
Organism: Caenorhabditis elegans
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Sequence: MRRKVETSWLEELKKRVKYQETSRLQMVEIRETLLDNEKELRSLDSTLKKTTSFMKKVKLLSAATVPQLIEELSKLNLSKFVEEMASGIIETKLKLSDIPKVTELCLAISAKYSNFSEQMAGEFKKVLPVKKSDKIANVAKLRVDIIFLAELCLCGVFNEKEGLQVLGAVLSYLIQTDKTDFVNVGLLATVSRTVGWQIANIVPIPMDDAETVEIQDEELPESSALSVEQKKSIRELFKSYYDSLYSKTEKTCSARNKAMKRVKRQERSRGDAGDEEKTTLNDLQSELDSLRKMAIEISSAIGVEMKPLKEEASDDEEDEAANLEMGRKLAEGAIKLWSDEETKAFYEDLIDLRQMVPKDLYKESEQRTLSKAKMAERIEDVDMENINESGAMDAKRSSLQRGESEKETTPEDSQLQALLKEAVDASEERGVSKWQSFVLDLDHLVSKYSTDQAAIYFVSNLNNKGCRKRLVKLMIDPPPSRIDVVPFYARLVATLENVMPDLTTEIVTQLLEKFRGFLQQKPSSATAIIKVESKMVCVMMIAELMKFGVISRAEGLSCLRQLVYDLRGHSVEMTATFMESSGLYLYRHTESHAKMKRLLEVVKAKRERMKDQRQAMLIDNAYFTCLPPEDSKEERLRLKLDEEDTPMKRFIRHIILDINESTVDVFLKCLRRLEWYDPEVADYAIRYLSSTWLLPIENLQHVASAIAGLCNLVHLQWIGMAVIDSTIETIRISLENPGVYNQWAHSAAVYLAELYSFELCDEDLVLKILYQLISYPEPENSWRDLHRIRMICAMLEILREFFMKGSGKIKMRYFLSYFHRYYYIKKDAWDQEVAEQQPNSGGETGENQNPLDVQTSFPYEVELAYTELCRQFRQKKSNSLRWPKNLKEAQDIVTKIEKKFKGELKEFAGEHKDIEGDGLNELNVIEEDDEEDEDENRDSELDEDDSEEDRQKIENFSNAVTKEEDDEFQRELDRMMGEGFRQSAMPVAAAQYDVTLPAAVKDRFNRSIKFAETVKDEPAASSSKQDNDDDEDVYEKSPTIAASGRQKQTRVTLMVRGKTNKPSLKTVNIDDDQLQERWKEEKAREEQERADMKRLTLGQHRRIEMEEEKALLASLNSSRKGNAKRGQFRPQFPKPHLEGEW
InterPro domains: - IPR016024: Armadillo-type fold (homologous_superfamily) [66-906]
- IPR003890: MIF4G-like, type 3 (domain) [48-870]
- IPR007193: Up-frameshift suppressor 2, C-terminal (domain) [954-1098]
- IPR039762: Nonsense-mediated mRNA decay protein Nmd2/UPF2 (family) [2-1109]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019899 (enzyme binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0044237 (cellular metabolic process), GO:0019222 (regulation of metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0009892 (negative regulation of metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0044248 (cellular catabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0034655 (nucleobase-containing compound catabolic process), GO:0009057 (macromolecule catabolic process), GO:0044270 (cellular nitrogen compound catabolic process), GO:0090304 (nucleic acid metabolic process), GO:0044265 (cellular macromolecule catabolic process), GO:0019439 (aromatic compound catabolic process), GO:1901361 (organic cyclic compound catabolic process), GO:0046700 (heterocycle catabolic process), GO:0010629 (negative regulation of gene expression), GO:0010468 (regulation of gene expression), GO:0016070 (RNA metabolic process), GO:0006402 (mRNA catabolic process), GO:0006401 (RNA catabolic process), GO:0016071 (mRNA metabolic process), GO:0000956 (nuclear-transcribed mRNA catabolic process), GO:0000184 (nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)