Protein: Protein VACUOLELESS GAMETOPHYTES (Q6NQN8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Essential for development of both female (megagametogenesis) and male (microgametogenesis) gametophytes by promoting the formation of large vacuoles early in development, maybe via the regulation of vesicular fusion.
Subcellular location: Endomembrane system {ECO:0000269|PubMed:28107777}. Prevacuolar compartment {ECO:0000269|PubMed:28107777}. Endosome, multivesicular body {ECO:0000269|PubMed:28107777}. Note=Localized to multivesicular bodies in gametophytes during mega- and microgametogenesis. {ECO:0000269|PubMed:28107777}.
Sequence: MASRPSVRHPSHNHPLRGHKAQVEDEIICSGCDLDLLGAYFKCTKSECDYFLHKSCFDLPREIRHKSHPDHPLILLYSPQNNNSTYTCDACGEYGSGFTYNCSICQYDVHVGCVSVPETMKHDEHVHPLALIYKAPCPKDHIFTCDVCDETMPHNLWLYYCQKCDYGAHLHSCVAEEEEKSKKGGRGRGGEGGSGGNGVNRGRSSANSELAAMLKAQREMEQMQIALHLEMQRAKIDKKSRKHMLKMI
InterPro domains: - IPR046349: C1-like domain superfamily (homologous_superfamily) [32-127]
- IPR043145: Zinc finger, ZZ-type superfamily (homologous_superfamily) [78-132]
- IPR004146: DC1 (domain) [10-170]
Interaction partners: - Senescence-induced receptor-like serine/threonine-protein kinase
- Probable LRR receptor-like protein kinase At1g51890
- pEARLI1-like lipid transfer protein 3
- Transmembrane protein
- Probable WRKY transcription factor 29
- Similarity to disease resistance protein domain family protein)
- Reticulon-like protein B4
- Dirigent protein 11
- Uncharacterized protein At3g61930
- Cytochrome P450 81F2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0023051 (regulation of signaling), GO:0023057 (negative regulation of signaling), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0001666 (response to hypoxia), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0010646 (regulation of cell communication), GO:0070482 (response to oxygen levels), GO:0009966 (regulation of signal transduction), GO:0071456 (cellular response to hypoxia), GO:1902532 (negative regulation of intracellular signal transduction), GO:1902531 (regulation of intracellular signal transduction), GO:0036293 (response to decreased oxygen levels), GO:0070297 (regulation of phosphorelay signal transduction system), GO:0036294 (cellular response to decreased oxygen levels), GO:0010104 (regulation of ethylene-activated signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0055044 (symplast), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0012505 (endomembrane system), GO:0030312 (external encapsulating structure), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0009506 (plasmodesma), GO:0070161 (anchoring junction), GO:0043227 (membrane-bounded organelle), GO:0005618 (cell wall), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0009505 (plant-type cell wall), GO:0005911 (cell-cell junction)