Protein: BTB/POZ domain-containing protein At1g30440 (Q9S9Q9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Sequence: MACMKLGSKSDAFQRQGQAWFCTTGLPSDIVVEVGEMSFHLHKFPLLSRSGVMERRIAEASKEGDDKCLIEISDLPGGDKTFELVAKFCYGVKLELTASNVVYLRCAAEHLEMTEEHGEGNLISQTETFFNQVVLKSWKDSIKALHSCDEVLEYADELNITKKCIESLAMRASTDPNLFGWPVVEHGGPMQSPGGSVLWNGISTGARPKHTSSDWWYEDASMLSFPLFKRLITVMESRGIREDIIAGSLTYYTRKHLPGLKRRRGGPESSGRFSTPLGSGNVLSEEEQKNLLEEIQELLRMQKGLVPTKFFVDMLRIAKILKASPDCIANLEKRIGMQLDQAALEDLVMPSFSHTMETLYDVDSVQRILDHFLGTDQIMPGGVGSPCSSVDDGNLIGSPQSITPMTAVAKLIDGYLAEVAPDVNLKLPKFQALAASIPEYARLLDDGLYRAIDIYLKHHPWLAETERENLCRLLDCQKLSLEACTHAAQNERLPLRIIVQVLFFEQLQLRTSVAGCFLVSDNLDGGSRQLRSGGYVGGPNEGGGGGGGWATAVRENQVLKVGMDSMRMRVCELEKECSNMRQEIEKLGKTTKGGGSASNGVGSKTWENVSKKLGFGFKLKSHQMCSAQEGSVSKSNNENVKIEKLKDVKERRGKHKKASSISSER
InterPro domains: - IPR043454: NPH3/RPT2-like family (family) [22-618]
- IPR027356: NPH3 domain (domain) [214-508]
- IPR000210: BTB/POZ domain (domain) [26-115]
- IPR011333: SKP1/BTB/POZ domain superfamily (homologous_superfamily) [6-119]
Interaction partners: - UDP-D-xylose:L-fucose alpha-1,3-D-xylosyltransferase MGP4
- Transmembrane 9 superfamily member 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0071704 (organic substance metabolic process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0044238 (primary metabolic process), GO:0104004 (cellular response to environmental stimulus), GO:1901564 (organonitrogen compound metabolic process), GO:0009314 (response to radiation), GO:0071214 (cellular response to abiotic stimulus), GO:0019538 (protein metabolic process), GO:0030522 (intracellular receptor signaling pathway), GO:0043170 (macromolecule metabolic process), GO:0009606 (tropism), GO:0071478 (cellular response to radiation), GO:0036211 (protein modification process), GO:0009416 (response to light stimulus), GO:0043412 (macromolecule modification), GO:0009638 (phototropism), GO:0009785 (blue light signaling pathway), GO:0009637 (response to blue light), GO:0070647 (protein modification by small protein conjugation or removal), GO:0071482 (cellular response to light stimulus), GO:0071483 (cellular response to blue light), GO:0032446 (protein modification by small protein conjugation), GO:0016567 (protein ubiquitination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)