Protein: Probable proteasome inhibitor (Q9M330)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Could play an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome (By similarity).
Sequence: MANSQTVMAMIRLARPPFRNNHDKVAFAIHSSFVASGYILTATGRPAFADEALSSSSQNDVGIEGWNEFEGEYAFVYANPKKGSKKILVKCLAMDDKLLVDAIADGGAEPAHLEIKVGDYAEESNEGDYSAQFKNLDKLVTDLQSEIIDKLDGKPKPVASRAQSSSETNEEPRYYDDTPNPLGPQIHPSGVVVPPIPGNGGYSDLFPGPGAGMYPGRGGFGDGSMLVGPTDPRFFPFGDGSDRPGFMGPPHPGMPPPGARFDPYGPPGVPGFEPGRFTRQPPRGPGGGHPDLEHFPGGSDFI
InterPro domains: - IPR021625: PI31 proteasome regulator, N-terminal (domain) [15-154]
- IPR045128: Proteasome inhibitor PI31-like (family) [1-298]
Interaction partners: - Proteasome subunit beta type-4
- Proteasome subunit beta type-1
- Proteasome subunit beta type-6
- Proteasome subunit alpha type-1-A
- Proteasome subunit beta type-7-A
- Proteasome subunit beta type-7-B
- Proteasome subunit alpha type-7-A
- Proteasome subunit alpha type-7-B
- Proteasome subunit alpha type-1-B
- ARM repeat superfamily protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0044237 (cellular metabolic process), GO:0019222 (regulation of metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0009893 (positive regulation of metabolic process), GO:0071704 (organic substance metabolic process), GO:0003006 (developmental process involved in reproduction), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0009791 (post-embryonic development), GO:0048316 (seed development), GO:1901564 (organonitrogen compound metabolic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0044248 (cellular catabolic process), GO:0048731 (system development), GO:0019538 (protein metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0009790 (embryo development), GO:0048608 (reproductive structure development), GO:0080090 (regulation of primary metabolic process), GO:0009793 (embryo development ending in seed dormancy), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0061458 (reproductive system development), GO:0009057 (macromolecule catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0006508 (proteolysis), GO:0051246 (regulation of protein metabolic process), GO:0044265 (cellular macromolecule catabolic process), GO:0030163 (protein catabolic process), GO:0051247 (positive regulation of protein metabolic process), GO:0010154 (fruit development), GO:0043632 (modification-dependent macromolecule catabolic process), GO:0051603 (proteolysis involved in protein catabolic process), GO:0019941 (modification-dependent protein catabolic process), GO:0006511 (ubiquitin-dependent protein catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)