Protein: Kinesin-like protein (Q9VRK9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Sequence: MPQEEANAGTTAQLDDEIENVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKPNATANEPPKTYYFDNVFDGGSNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGIIPNAFAHIFGHIAKAKENQKFLVRVSYMEIYNEEVRDLLGKDVGKSLEVKERPDIGVFVKDLSGYVVHNADDLENIMRLGNKNRAVGATKMNQESSRSHAIFSITVERSELGEGDVQHVRMGKLQLVDLAGSERQSKTQASGQRLKEATKINLSLSVLGNVISALVDGKSTHIPYRNSKLTRLLQDSLGGNSKTVMCATISPADSNYMETISTLRYASRAKNIQNRMHINEEPKDALLRHFQEEIARLRKQLEEGDSLEEEPPSSEEEEDTADDELEAPLEIELESSTIQAVEKKPKKKREKTDAEKEELAKRKNEHQKEIEHAKTEQETLRNKLVSLEGKILVGGENLLEKAQTQELLLEQSIAELEQHEKSEEALKQTLQQKATERIDIEERYSTLQDASTGITKKIHRVMQMLMGVKSELADQQQEHQREKEGIYENIRSLSRELALCELVLNSYVPKEYQSMINQYTHWNEDIGEWQLKCVAYTGNNMRKHISAHKTSGKEPDFLDLSHVYLSYNTDGVSNPMRSKSARPRTSGVPRPTTARRY
InterPro domains: - IPR027640: Kinesin-like protein (family) [19-577]
- IPR019821: Kinesin motor domain, conserved site (conserved_site) [251-262]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [20-385]
- IPR036961: Kinesin motor domain superfamily (homologous_superfamily) [19-371]
- IPR001752: Kinesin motor domain (domain) [18-360]
Interaction partners: - Kinesin associated protein 3, isoform G
- Kinesin-like protein Klp68D
- No mechanoreceptor potential B, isoform D
- Protein smoothened
- Kinesin-like protein
- Suppressor of fused homolog
- Intraflagellar transport protein 122 homolog
- Intraflagellar transport protein 57 homolog
- Kurtz arrestin
- Reduced mechanoreceptor potential A, isoform B
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003774 (cytoskeletal motor activity), GO:0140657 (ATP-dependent activity), GO:0003777 (microtubule motor activity), GO:0005515 (protein binding), GO:0008574 (plus-end-directed microtubule motor activity), GO:0019899 (enzyme binding), GO:0008092 (cytoskeletal protein binding), GO:0051020 (GTPase binding), GO:0019902 (phosphatase binding), GO:0031267 (small GTPase binding), GO:0019903 (protein phosphatase binding), GO:0008157 (protein phosphatase 1 binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0008152 (metabolic process), GO:0042592 (homeostatic process), GO:0048519 (negative regulation of biological process), GO:0051641 (cellular localization), GO:0048856 (anatomical structure development), GO:0023057 (negative regulation of signaling), GO:0009653 (anatomical structure morphogenesis), GO:0031503 (protein-containing complex localization), GO:0022402 (cell cycle process), GO:0007389 (pattern specification process), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0048871 (multicellular organismal-level homeostasis), GO:0009791 (post-embryonic development), GO:0007267 (cell-cell signaling), GO:0050793 (regulation of developmental process), GO:0048522 (positive regulation of cellular process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0007165 (signal transduction), GO:0051640 (organelle localization), GO:0048869 (cellular developmental process), GO:0009628 (response to abiotic stimulus), GO:0007275 (multicellular organism development), GO:0007049 (cell cycle), GO:0051234 (establishment of localization), GO:0071704 (organic substance metabolic process), GO:0033036 (macromolecule localization), GO:0044237 (cellular metabolic process), GO:0051235 (maintenance of location), GO:0098727 (maintenance of cell number), GO:0006950 (response to stress), GO:0019827 (stem cell population maintenance), GO:0007017 (microtubule-based process), GO:0048585 (negative regulation of response to stimulus), GO:0007154 (cell communication), GO:0044238 (primary metabolic process), GO:0009968 (negative regulation of signal transduction), GO:0002165 (instar larval or pupal development), GO:0007552 (metamorphosis), GO:0044085 (cellular component biogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0009314 (response to radiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009966 (regulation of signal transduction), GO:0045184 (establishment of protein localization), GO:0045787 (positive regulation of cell cycle), GO:0006793 (phosphorus metabolic process), GO:0035295 (tube development), GO:0051726 (regulation of cell cycle), GO:0009887 (animal organ morphogenesis), GO:0046907 (intracellular transport), GO:0051656 (establishment of organelle localization), GO:0045595 (regulation of cell differentiation), GO:0016043 (cellular component organization), GO:0007166 (cell surface receptor signaling pathway), GO:0009790 (embryo development), GO:0009886 (post-embryonic animal morphogenesis), GO:0007098 (centrosome cycle), GO:0008284 (positive regulation of cell population proliferation), GO:0035239 (tube morphogenesis), GO:0007276 (gamete generation), GO:0048736 (appendage development), GO:0010648 (negative regulation of cell communication), GO:1903047 (mitotic cell cycle process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0009799 (specification of symmetry), GO:0051649 (establishment of localization in cell), GO:0035107 (appendage morphogenesis), GO:0000226 (microtubule cytoskeleton organization), GO:0043170 (macromolecule metabolic process), GO:0060249 (anatomical structure homeostasis), GO:0007059 (chromosome segregation), GO:0042127 (regulation of cell population proliferation), GO:0009888 (tissue development), GO:0003002 (regionalization), GO:0010646 (regulation of cell communication), GO:0051653 (spindle localization), GO:0035152 (regulation of tube architecture, open tracheal system), GO:0006810 (transport), GO:0070727 (cellular macromolecule localization), GO:0001894 (tissue homeostasis), GO:0000278 (mitotic cell cycle), GO:0045664 (regulation of neuron differentiation), GO:0007346 (regulation of mitotic cell cycle), GO:0071705 (nitrogen compound transport), GO:0030705 (cytoskeleton-dependent intracellular transport), GO:0048707 (instar larval or pupal morphogenesis), GO:0090596 (sensory organ morphogenesis), GO:0048732 (gland development), GO:0051220 (cytoplasmic sequestering of protein), GO:0071702 (organic substance transport), GO:0051169 (nuclear transport), GO:0007052 (mitotic spindle organization), GO:0051294 (establishment of spindle orientation), GO:0007350 (blastoderm segmentation), GO:0035272 (exocrine system development), GO:0099111 (microtubule-based transport), GO:0048666 (neuron development), GO:0009948 (anterior/posterior axis specification), GO:0022607 (cellular component assembly), GO:0051983 (regulation of chromosome segregation), GO:0051225 (spindle assembly), GO:0006886 (intracellular protein transport), GO:0043412 (macromolecule modification), GO:0007399 (nervous system development), GO:0048737 (imaginal disc-derived appendage development), GO:0007292 (female gamete generation), GO:0015031 (protein transport), GO:0048599 (oocyte development), GO:0048563 (post-embryonic animal organ morphogenesis), GO:0007560 (imaginal disc morphogenesis), GO:0007444 (imaginal disc development), GO:0048858 (cell projection morphogenesis), GO:0061024 (membrane organization), GO:1902850 (microtubule cytoskeleton organization involved in mitosis), GO:0010970 (transport along microtubule), GO:0098813 (nuclear chromosome segregation), GO:0007224 (smoothened signaling pathway), GO:0035120 (post-embryonic appendage morphogenesis), GO:0140014 (mitotic nuclear division), GO:0007423 (sensory organ development), GO:0035114 (imaginal disc-derived appendage morphogenesis), GO:0006796 (phosphate-containing compound metabolic process), GO:1902532 (negative regulation of intracellular signal transduction), GO:0008589 (regulation of smoothened signaling pathway), GO:0036211 (protein modification process), GO:0045880 (positive regulation of smoothened signaling pathway), GO:0022008 (neurogenesis), GO:1901987 (regulation of cell cycle phase transition), GO:0048569 (post-embryonic animal organ development), GO:0008104 (protein localization), GO:0060429 (epithelium development), GO:0006996 (organelle organization), GO:0000070 (mitotic sister chromatid segregation), GO:0022612 (gland morphogenesis), GO:0030182 (neuron differentiation), GO:1902531 (regulation of intracellular signal transduction), GO:0009952 (anterior/posterior pattern specification), GO:0060541 (respiratory system development), GO:0006606 (protein import into nucleus), GO:0048592 (eye morphogenesis), GO:0046552 (photoreceptor cell fate commitment), GO:0007472 (wing disc morphogenesis), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0007424 (open tracheal system development), GO:0150063 (visual system development), GO:0016310 (phosphorylation), GO:0007010 (cytoskeleton organization), GO:0042461 (photoreceptor cell development), GO:0060119 (inner ear receptor cell development), GO:0035315 (hair cell differentiation), GO:0048699 (generation of neurons), GO:0007476 (imaginal disc-derived wing morphogenesis), GO:0044782 (cilium organization), GO:0070925 (organelle assembly), GO:0006913 (nucleocytoplasmic transport), GO:0033365 (protein localization to organelle), GO:0035214 (eye-antennal disc development), GO:0046530 (photoreceptor cell differentiation), GO:0006468 (protein phosphorylation), GO:0120036 (plasma membrane bounded cell projection organization), GO:0035220 (wing disc development), GO:0007455 (eye-antennal disc morphogenesis), GO:0031175 (neuron projection development), GO:0001738 (morphogenesis of a polarized epithelium), GO:0009913 (epidermal cell differentiation), GO:0050954 (sensory perception of mechanical stimulus), GO:0034502 (protein localization to chromosome), GO:0098930 (axonal transport), GO:0048812 (neuron projection morphogenesis), GO:0061564 (axon development), GO:0042462 (eye photoreceptor cell development), GO:0007409 (axonogenesis), GO:0051383 (kinetochore organization), GO:0048749 (compound eye development), GO:0001745 (compound eye morphogenesis), GO:0140694 (non-membrane-bounded organelle assembly), GO:0001754 (eye photoreceptor cell differentiation), GO:0001751 (compound eye photoreceptor cell differentiation), GO:0042051 (compound eye photoreceptor development), GO:0031623 (receptor internalization), GO:0071459 (protein localization to chromosome, centromeric region), GO:1903083 (protein localization to condensed chromosome)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005875 (microtubule associated complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005871 (kinesin complex), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015630 (microtubule cytoskeleton)