Protein: ESF1 homolog (ESF1, nucleolar pre-rRNA-processing protein, homolog (S. cerevisiae)) (B8JKQ1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Sequence: MTSKNTASGDDRFSKVKKDPRFWEMPNKERKIKIDKRFQSMFHDERFKLKYTVDKRGRPVKHTSTEDLKRFYKLSDSEQSDDDDDDEDEEKTEEEQKEKRGFEADKEAEVEEDDDDYEEEEGESDESEQEEEQKIQRNKEAKKTKKGVRVYEEDEDVESGVEEDDDDDDDDDEEESDSGPDLARGKGNIETSSDEDEEDEGDEVEDLLQREKEEIEHDWGEMWKDAPRSDDTSRRLAVCNMDWDRLKAKDLLALFNSFKPKGGVVLSVTVYPSEFGKERIHAEQTQGPLELSSLPENPDADTDEQRIYREKVRDYQFKRLRYYYAVVECDSAETASKIYEECDGIEYETSCSMIDLRFIPDDVTFDDEPKDRATDVDYGSYKPKLFTSTATTTSKVELTWDETDHDRVSALCRKFNKDELLDMDFKAYLASSSEEDEDEEEEQTKAVKPVESLPEEKKASKGKKGSGQIDKYRELLKSIQDKDKKKEDDDNNMNMEITWVPGLKESTENLVKKKMMGKDRLTPWEEFLEKKKEKKKEKRKGKKEVVEAELQISDDELPPDVDLSDPFFTEELVSTASLKNKESKKNRKKEEERTPEEQEEMERRKAEMELLMDDDEDDKHKHFNYDKIVEHQNLSKKKRKKLLKSNTPLEEGDDFKVDVQDPRFQAMFTSHLYNLDPSDPAYKKTKATQSILEEKQRRREEKHSQEETRRSKHTQEEDKTHTPSASSSTMDPSLSLLIKSVKNKTQQFQARKKQKTK
InterPro domains: - IPR039754: Pre-rRNA-processing protein Esf1 (family) [152-756]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [150-358]
- IPR056750: ESF1, RRM domain (domain) [234-374]
- IPR012580: NUC153 (domain) [661-688]
Interaction partners: - Something about silencing protein 10
- ATP-dependent RNA helicase
- DEAD
- UTP6 small subunit processome component.
- UTP18 small subunit processome component.
- Nucleolar protein 6
- RNA cytidine acetyltransferase
- Activator of basal transcription 1
- Nucleolar protein 10
- Nucleolar MIF4G domain-containing protein 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0048732 (gland development), GO:0061008 (hepaticobiliary system development), GO:0010467 (gene expression), GO:0031016 (pancreas development), GO:0042254 (ribosome biogenesis), GO:0016070 (RNA metabolic process), GO:0001889 (liver development), GO:0006396 (RNA processing), GO:0034470 (ncRNA processing), GO:0006364 (rRNA processing), GO:0034660 (ncRNA metabolic process), GO:0016072 (rRNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)