Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q57V67)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MAQVADECKALSSELFLSKYRIMKGIGKGSFGEAVLVRSKEDGKRYVAKAIESAAMSAKEKRDVQNEIRILAAANHPNIIRYHEHFEDGTLIFIVMEYADGGDLNTRIKDAKKNDPVVPFEPKLAMFWFLQICMALKYLHDNHILHRDLKTANIFLTAKNVVKLGDFGISTVVQNTLACAKTVCGTPYYFSPELCQNKPYNNKSDVWALGVILYELLTLQRPFLARSLKELLKKILVGQYEPIPSTVPAEIRGLCGALLQVNPVQRPSINRILESPFVQESLKGFSADLEKQAEKERAEYEARNPKITKPVKPVSTPEKPKEYPKEPQLSQKEQMAKLRGMNRESIKAMLAEQAAAGPPQEQQQQSPSKSEQDDGHHEVDDDGEYIEQKKLIVEQSKNIVGKTNLGGHPEEFGDGPSDSSPQEDMIILSSGKSVPASQVRAILEKEIGVKLLNEAAELVNQLMLNNEISNVDIQKQLNELLGAQHAHHSNAITKLCVYEGKKM
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [16-279]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [144-156]
- IPR051131: NEK Ser/Thr protein kinase family, NIMA subfamily (family) [18-425]
- IPR001245: Serine-threonine/tyrosine-protein kinase, catalytic domain (domain) [96-269]
- IPR017441: Protein kinase, ATP binding site (binding_site) [26-49]
- IPR000719: Protein kinase domain (domain) [20-278]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:0016740 (transferase activity), GO:1901363 (heterocyclic compound binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0140096 (catalytic activity, acting on a protein), GO:0097367 (carbohydrate derivative binding), GO:1901265 (nucleoside phosphate binding), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0004672 (protein kinase activity), GO:0043168 (anion binding), GO:0000166 (nucleotide binding), GO:0032553 (ribonucleotide binding), GO:0035639 (purine ribonucleoside triphosphate binding), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0032555 (purine ribonucleotide binding), GO:0017076 (purine nucleotide binding), GO:0005524 (ATP binding), GO:0032559 (adenyl ribonucleotide binding), GO:0030554 (adenyl nucleotide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0006793 (phosphorus metabolic process), GO:0036211 (protein modification process), GO:0006796 (phosphate-containing compound metabolic process), GO:0043412 (macromolecule modification), GO:0006468 (protein phosphorylation), GO:0016310 (phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0036064 (ciliary basal body), GO:0043233 (organelle lumen), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005929 (cilium), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0031981 (nuclear lumen), GO:0005634 (nucleus), GO:0015630 (microtubule cytoskeleton)