Protein: Peptidase, putative (EC 3.4.24.-) (Q57YQ9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MTREEVRIVTPSVLRVQHFGYIFKNGVKCIVVQDPNARVPAAAMNIRAGQLNDPEVLPGLAHFCEHMLFMGTEKYPSEGEYSDYITKNGGYCNAWTADRGTTYYFTVAQDALQGALERFVEFFIAPSFDASSISREVKAVHSEDEKNHSVDFWRQDELLRSLCDPRHPRSRYGNGNMTTLWDEPLQKQVDIREQLLKFFEAHYVSGAACIAVYSAFPPEWVLSIIEEPLSKMRVGEPSPFRFMQPSDPLLRSTASGGLWLNVRTVRKTRSIAMIWPVKSHSSLWRSSPSGYVSYILGHECDSSVFGILRQQGLAVAMSVGPRRIDDDNELFCVDISLTLDGVRCIPDVIDMVYQGIGQTAHVDTSVYEHMKSEELLSFESCDISGYADHCVELAYSANETDLPNCWVSGNRVLEDDIHATEEYVAQLTPEKCVITFMWGDMPCSTDDDTPREEGPESAIEEEEEDAEESEEEQCASSVFHTLPNFAQIPCNCATRFHKTKFSLCRVPDDLLRRWAASLHKPTQAGLSLPPPNPFLATDFTLYNEGSSDGHCEPAVETFNTMYGVTLMRKNVWHYQTFKSSIHWCALSPCVYATPKNRFYARVMRSILKDALAEVSYFGVLASLENSVELSTGGISLSVTGPQQRIVDFFFSLFEKFFSPNVLRGTAEKYNTYSEVALRHLVGSAAKQPYELVNDAFVKVGKVVMYTFDEILNAASSISYKEYLSFVDEYLRSGIYFECFIAGNIPSASYMRECLLDTMEKKLSCMNVPPAPKESIPRFRDAYAFSRDSSKLGTPVVSVMSYPPFNPENPNVAVLLDIYVGEETAMVRALCDCMNKLLSSSFFNELRTKEALGYIVFSRSLRLQGTAHLQFGVQSAVEGVDGLYLFSRIIAFLAAVEEKLVAVCSETDVQTVVSGLIEARKKLPDSADHDCDDLSGRYLNPLGIQGKEAVVAALEQVSPQMVREFFQTYVANSNPHRKAVLTIVNSSASAATDAFNTDQEEVALPSRRPCEGAQPIDGDDVAAANRGCVLNLPDFTAVPMRIAIKRYGSPQEFQANLPVIRCRTF
InterPro domains: - IPR032632: Peptidase M16, middle/third domain (domain) [483-713]
- IPR007863: Peptidase M16, C-terminal (domain) [192-356]
- IPR050626: Peptidase M16 (family) [11-992]
- IPR054734: Coenzyme PQQ synthesis protein F-like, C-terminal lobe, domain 4 (domain) [833-926]
- IPR001431: Peptidase M16, zinc-binding site (binding_site) [49-72]
- IPR011765: Peptidase M16, N-terminal (domain) [30-165]
- IPR011249: Metalloenzyme, LuxS/M16 peptidase-like (homologous_superfamily) [21-980]
Interaction partners: - CAAX prenyl protease
- Cytosolic leucyl aminopeptidase, putative
- Peroxin-13
- Peroxisome targeting signal 1 receptor
- Polyubiquitin, putative
- Proteasome 26S non-ATPase subunit 9, putative
- Nonspecific lipid-transfer protein, putative
- propanoyl-CoA C-acyltransferase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0004175 (endopeptidase activity), GO:0008237 (metallopeptidase activity), GO:0004222 (metalloendopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0044248 (cellular catabolic process), GO:0009057 (macromolecule catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0006508 (proteolysis), GO:0044265 (cellular macromolecule catabolic process), GO:0030163 (protein catabolic process), GO:0043632 (modification-dependent macromolecule catabolic process), GO:0051603 (proteolysis involved in protein catabolic process), GO:0019941 (modification-dependent protein catabolic process), GO:0006511 (ubiquitin-dependent protein catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)