Protein: TIP41-like protein (Q8VXY4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in the regulation of the TOR signaling pathway. Indirectly activates the PP2A phosphatase via interaction with its suppressor TAP46. Could play a role in cytoskeleton functions.
Sequence: METVVDKDVLKSSGAELLPDGRRGLRIHDWEIETLRGTILTSLAVEEWEKKLKTSHLPEMVFGENALVLKHLGSNTKIHFNAFDALAGWKQEGLPPVEVPAAAQWKFRSKPSQQVILDYDYTFTTPYCGSEVVEKDKETVEAKANPKGEATLQWENCEDQIDLAALSLKEPILFYDEVVLYEDELADNGVSLLTVKVRVMPSSWFLLLRFWLRVDGVLMRLRETRMHYRFGEDEAPTVLRENCWREATFQSLSAKGYPVDLAVWSDPSSISQRLPVIKHTTQKLKIPSKV
InterPro domains: - IPR007303: TIP41-like protein (family) [60-252]
- IPR051330: Phosphatase regulators and Met sulfoxide reductases (family) [22-287]
Interaction partners: - Aquaporin TIP4-1
- RGS1-HXK1-interacting protein 1
- Vacuolar fusion protein MON1 homolog
- Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A gamma isoform
- PP2A regulatory subunit TAP46
- AT4g33380/F17M5_140
- AP-2 complex subunit mu
- Serine/threonine-protein phosphatase PP2A-1 catalytic subunit
- F-box/kelch-repeat protein At5g15710
- non-specific serine/threonine protein kinase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0016787 (hydrolase activity), GO:0003676 (nucleic acid binding), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0016791 (phosphatase activity), GO:0003993 (acid phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0007154 (cell communication), GO:0001101 (response to acid chemical), GO:0009991 (response to extracellular stimulus), GO:1901700 (response to oxygen-containing compound), GO:0031668 (cellular response to extracellular stimulus), GO:0009414 (response to water deprivation), GO:0010035 (response to inorganic substance), GO:0104004 (cellular response to environmental stimulus), GO:0009415 (response to water), GO:0071496 (cellular response to external stimulus), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0071214 (cellular response to abiotic stimulus), GO:1902074 (response to salt), GO:0042631 (cellular response to water deprivation), GO:0071229 (cellular response to acid chemical), GO:0071462 (cellular response to water stimulus), GO:1901701 (cellular response to oxygen-containing compound), GO:1902075 (cellular response to salt)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)