wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Glutathione peroxidase (Q6ESJ0)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Not known
Sequence: MPSRTAPFISRLRLLRTAAALSPFSSSAPPRHSPRILRAIPVGAPHPPRVSAAVSPLVRPVAAGFALFSMATAASSAASVHDFTVKDASGKDVDLSTFKGKVLLIVNVASQCGLTNSNYTELSQLYEKYKDQGFEILAFPCNQFGGQEPGTNEEIVQFACTRFKAEYPIFDKVDVNGDNTAPIYKFLKSSKGGLFGDNIKWNFSKFLVDKEGRVVERYAPTTSPLSMEKDIKKLLGSS
InterPro domains: - IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [79-236]
- IPR013766: Thioredoxin domain (domain) [74-236]
- IPR000889: Glutathione peroxidase (family) [70-238]
- IPR029759: Glutathione peroxidase active site (active_site) [100-115]
- IPR029760: Glutathione peroxidase conserved site (conserved_site) [137-144]
Interaction partners: - Glutathione hydrolase
- Glutathione synthetase
- Glutathione reductase
- Probable glutathione S-transferase DHAR1, cytosolic
- Os01g0151400 protein
- Os01g0151500 protein
- Glutathione reductase, cytosolic
- Probable glutathione S-transferase DHAR2, chloroplastic
- Os11g0125601 protein
- Glutathione S-transferase 3, mitochondrial
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0016209 (antioxidant activity), GO:0003824 (catalytic activity), GO:0004601 (peroxidase activity), GO:0016491 (oxidoreductase activity), GO:0016684 (oxidoreductase activity, acting on peroxide as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0006950 (response to stress), GO:0006979 (response to oxidative stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Uncharacterized TLC domain-containing protein C17A2.02c (O13752)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Not known
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein {ECO:0000269|PubMed:16823372}.
Sequence: MSSAVTPSDQGLLPRGPIALEEFVKPFCDRFGLTKLPRHMHVILLSALFYQIINILSPVISRHLSTHYAKLSKKTRLNWDAHVVSSVQSIVLICLGYTCLKEVNAFPDKLFGYSVVAGDIYALTAGYFVWDLYITVRYVHITGIGFVIHAIAALFVITFSYRPYLMYYGPTYLSWELSTPFLNIHYFLDKTNRTGSKFQMINGFILIVTFICVRIAWGWFSAYSTAIEILNHINVAPWALSLFYLAANMSLNCLNLFWVSKMIDAIRRRAHGEKKSTPLQVTSEYAKKNI
InterPro domains: - IPR006634: TRAM/LAG1/CLN8 homology domain (domain) [74-271]
- IPR050846: TLC domain-containing (family) [40-270]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016410 (N-acyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006629 (lipid metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006643 (membrane lipid metabolic process), GO:0006672 (ceramide metabolic process), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0046467 (membrane lipid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0006665 (sphingolipid metabolic process), GO:0046513 (ceramide biosynthetic process), GO:0030148 (sphingolipid biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Amino acid transporter, putative (Q381J1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MSDKGKCATDVENTTSPVTQQTFPAEPSGIVDASEPIHTDDKNKRVDARGDAPPSVWQSFSAKMKHIAGTVVPYGGLVSSVFNLCSVCIGAGILGLPAAANRSGLVMAMLYLVVIGGLGVFSLHILSLVMEKTGLRTFEHTARGVMGRRFEYFVVVIRWINSFGATVSYVISVGHVLNPIIEKSCGAPEFLRTPGGIRLLTALTWMVFMLPLVLPKRVNSLRYVSGFAIIFVLYFVFAIVIHGAQSGLPKLTSDEEDGVKLFNTGNSAIASVGVFMFAYVCQINCYEVYWEMKKRSCARFTVYAAISMAFCGILYALTILFAYGEFGGAIDNSILLMYNPITEVMMMIGFIGMVVKLCVAYALQTMALRNTIYHVLGWELETLPYWKHFSFVIPLSLVVLLAGLFIPNINTVFGIVGAICGGFLSFIFPSLFYMYSGKWTRRNVGNFHFFGTYFLLCAGVVGLVFGTVSVVSENILALIANKVEVVRVRAPETQC
InterPro domains: - IPR013057: Amino acid transporter, transmembrane domain (domain) [77-470]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901474 (azole transmembrane transporter activity), GO:0005342 (organic acid transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity), GO:0046943 (carboxylic acid transmembrane transporter activity), GO:0015171 (amino acid transmembrane transporter activity), GO:0015173 (aromatic amino acid transmembrane transporter activity), GO:0015174 (basic amino acid transmembrane transporter activity), GO:0015179 (L-amino acid transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0009628 (response to abiotic stimulus), GO:0009314 (response to radiation), GO:0006810 (transport), GO:0009416 (response to light stimulus), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:0015849 (organic acid transport), GO:0006865 (amino acid transport), GO:0015711 (organic anion transport), GO:0046942 (carboxylic acid transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Gnt-II system L-idonate transporter (L-Ido transporter) (L-idonate transporter) (5-keto-D-gluconate transporter) (L-idonate/5-ketogluconate/gluconate transporter) (P39344)
Organism: Escherichia coli (strain K12)
Function: Transports L-idonate, D-gluconate and 5-keto-D-gluconate, from the periplasm across the inner membrane.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000255}.
Sequence: MPLIIIAAGVALLLILMIGFKVNGFIALVLVAAVVGFAEGMDAQAVLHSIQNGIGSTLGGLAMILGFGAMLGKLISDTGAAQRIATTLIATFGKKRVQWALVITGLVVGLAMFFEVGFVLLLPLVFTIVASSGLPLLYVGVPMVAALSVTHCFLPPHPGPTAIATIFEANLGTTLLYGFIITIPTVIVAGPLFSKLLTRFEKAPPEGLFNPHLFSEEEMPSFWNSIFAAVIPVILMAIAAVCEITLPKTNTVRLFFEFVGNPAVALFIAIVIAIFTLGRRNGRTIEQIMDIIGDSIGAIAMIVFIIAGGGAFKQVLVDSGVGHYISHLMTGTTLSPLLMCWTVAALLRIALGSATVAAITTAGVVLPIINVTHADPALMVLATGAGSVIASHVNDPGFWLFKGYFNLTVGETLRTWTVMETLISIMGLLGVLAINAVLH
InterPro domains: - IPR003474: Gluconate transporter (family) [1-439]
Interaction partners: - Probable 3-phenylpropionic acid transporter
- Siroheme synthase
- 5-keto-D-gluconate 5-reductase
- Thermosensitive gluconokinase
- Uncharacterized protein YjgR
- HTH-type transcriptional regulator IdnR
- L-idonate 5-dehydrogenase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity), GO:0005342 (organic acid transmembrane transporter activity), GO:0046943 (carboxylic acid transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0006810 (transport), GO:1903825 (organic acid transmembrane transport), GO:1905039 (carboxylic acid transmembrane transport), GO:0071702 (organic substance transport), GO:0015849 (organic acid transport), GO:0015711 (organic anion transport), GO:0046942 (carboxylic acid transport), GO:0015718 (monocarboxylic acid transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Exportin-1/Importin-beta-like domain-containing protein (Q38AK6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MSVERIVQILSVVYAAEDNGDRRRATFELHEVEEQMNSEEIVSIGTGLLAVTDRGAAVQAYGAVLLRNAVVSGRIPPSVVPYEELMTWYFNEPTLGRLLCADIVELLIECMVREWPESYPDLIARVCAPPTQLAQQPRKLHFLSSFIAHITSPHVGGVPVNRMKRLKKAIELYGRTILVEVIQALFDLYTQAGGAASNSCAPGTKESVTDCLMTVANATPCLPVHVWSEVGLTNTLSALVRWGPAAQEALAATTALLRCDRLSCAGESTAADSLRTELLNVALGSVDMWVAESNHGNIEEVVGLLHDSPDTLLQPAAPVAGRVCLLTLSIPSVLLASVACSIFRRLGDAAFTQINPLELLARLAVLVPKNKLHPCCGTCEGGMQISEHDFGTVEAFTQAFSEFRSLAAHVLTSVARIYPVVANQFMLQLVSNLSDSRGTEEDARTQCGFVTQRSDTFCNWEATQFLLYSLSESFKHSSEYVPQIINELVKREPEDMVIFPVYLNMLSLLWNCRDDTALGVWQGTMGIILKSLGNRYREVNDIDVVSARKRALTLLVTACSKHAKQLVLLGEPFLCQMERLLMFSSTSAMERTLLYEAIAAFTTALPEDEAQRRLQSFLDPVAKIMVDHTTNMCQNAFNDIIIGRTTAQRDEGYVIRDSINVFAGVLRRCKTLPYVVEAASSLVPSIMKLMEFAHNIDAKDLPPEYKTLFGTYNGDGGAASHLRSREGEGAGGRKSDVYRARKILLDIRLALYQVIGALSSFFSVEPLENMLQMLVCVTRLLPIHAMRQLLSHCLFPVASAQERLIPATLSVCTTFYMQRNRGASRAPEAEAVDGRQLFGLSKDIFAFIRQNVVDPKRLDGNPALCQIVVDVTLSVLESGVNIAEASRFISAIVSNGNDANRFSGTANAQMVDMALCAYRRMIDFAVRADESLLPPREREKLLVTLADTYVSQYPLYVTAMKDRYPQPQVDELNTHLTMMGRIDVKRRYFKEFLQRFAGQVCVDGGQEGDR
InterPro domains: - IPR016024: Armadillo-type fold (homologous_superfamily) [1-778]
- IPR011989: Armadillo-like helical (homologous_superfamily) [1-821]
- IPR045065: Exportin-1/5 (family) [2-813]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140104 (molecular carrier activity), GO:0140142 (nucleocytoplasmic carrier activity), GO:0005049 (nuclear export signal receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0046907 (intracellular transport), GO:0045184 (establishment of protein localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0051169 (nuclear transport), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0008104 (protein localization), GO:0015031 (protein transport), GO:0006913 (nucleocytoplasmic transport), GO:0006611 (protein export from nucleus), GO:0051168 (nuclear export)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Ig-like domain-containing protein (A0A4W8)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Sequence: MLLSRLLPLLWVLKWASGNCFILPREVIGTYPSLTLELQSVTVQEGLCVLVPCHLIEYPMNRWSDAAFGYWFHEGENTHPDSLVATNKPYQLVQKEMQSRFHFSGDCSLDIRDAQKGDNGSYFFRLEKGGKTWNFCEERISVHVTDLTHSPNISIPQTLELGRPTNVMCSVPWACERGTPPIFSWMSAALISLGPTTTLSSVLTLTPRLQDHGTNLTCQVTFPGAGVTVQKTIQIDVTWKPRPLADVVQVAMGEAAIKFLLLGICFFFLSKRSHTKRVERPATHMDQAHAVMD
InterPro domains: - IPR013106: Immunoglobulin V-set domain (domain) [40-134]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [31-233]
- IPR007110: Immunoglobulin-like domain (domain) [32-234]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [33-242]
- IPR051036: Sialic acid-binding Ig-like lectin (family) [2-243]
- IPR003599: Immunoglobulin domain subtype (domain) [38-238]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0038024 (cargo receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0051649 (establishment of localization in cell), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport), GO:0006897 (endocytosis), GO:0006898 (receptor-mediated endocytosis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009986 (cell surface)
Protein: TRAF family member associated NFKB activator (E7EQA9)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MDKNIGEQLNKAYEAFRQACMDRDSAVKELQQKTENYEQRIREQQEQLSLQQTIIDKLKSQLLLVNSTQDNNYGCVPLLEDSETRKNNLTLDQPQDKVISGIAREKLPKVRRQEVSSPRKETSARSLGSPLLHERGNIEKTFWDLKEEFHKICMLAKAQKDHLSKLNIPDTATETQCSVPIQCTDKTDKQEALFKPQAKDDINRGAPSITSVTPRGLCRDEEDTSFESLSKFNVKFPPMDNDSTFLHSTPERPGILSPATSEAVCQEKFNMEFRDNPGNFVKTEETLFEIQGIDPIASAIQNLKTTDKTKPSNLVNTCIRTTLDRAACLPPGDHNALYVNSFPLLDPSDAPFPSLDSPGKAIRGPQQSVHSCFSRWHPALYICFLYYSKGNSCPFGSPFLIKTVTRWY
InterPro domains: - IPR039669: TRAF family member-associated NF-kappa-B activator (family) [1-371]
- IPR024581: Tbk1/Ikki binding domain (domain) [133-186]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Transcriptional regulator Myc-A (c-Myc-A) (zc-Myc) (P52160)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.
Subcellular location: Nucleus.
Sequence: MERHSLNTSVKMPVSASLACKNYDYDYDSIQPYFYFDNDDEDFYHHQQGQTQPSAPSEDIWKKFELLPTPPLSPSRRQSLSTAEQLEMVSEFLGDDVVSQSFICDDADYSQSFIKSIIIQDCMWSGFSAAAKLEKVVSERLASLHAERKELMSDSNSNRLNASYLQDLSTSASECIDPSVVFPYPLTECGKAGKVASPQPMLVLDTPPNSSSSSGSDSEDEEEEDEEEEEEEEEEEEEEEEEEIDVVTVEKRQKRHETDASESRYPSPLVLKRCHVSTHQHNYAAHPSTRHDQPAVKRLRLEASNNHSINSSSSNRHVKQRKCASPRTSDSEDNDKRRTHNVLERQRRNELKLSFFALRDEIPEVANNEKAAKVVILKKATECIHSMQLDEQRLLSIKEQLRRKSEQLKHRLQQLRSSH
InterPro domains: - IPR050433: Myc family transcription factors (family) [19-417]
- IPR002418: Transcription regulator Myc (family) [12-418]
- IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [327-418]
- IPR011598: Myc-type, basic helix-loop-helix (bHLH) domain (domain) [335-393]
- IPR012682: Transcription regulator Myc, N-terminal (domain) [13-326]
- IPR003327: Leucine zipper, Myc (domain) [390-419]
Interaction partners: - Kruppel-like factor 4.
- Biklf
- Cellular tumor antigen p53
- Mitogen-activated protein kinase
- G1/S-specific cyclin-D1
- Catenin beta-1
- Transcription factor Sox-2
- POU domain, class 5, transcription factor 1
- Ubiquitin-specific peptidase 28
- Mitogen-activated protein kinase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003690 (double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0030154 (cell differentiation), GO:0048468 (cell development), GO:0002244 (hematopoietic progenitor cell differentiation), GO:0030097 (hemopoiesis), GO:0060216 (definitive hemopoiesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Endonuclease or glycosyl hydrolase with C2H2-type zinc finger domain-containing protein (F4K209)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MSTAEADYVKAKTSVWWDIENCEVPRGWDAHVIALNVSSSLLKMNYCGPVSISAYGDTNLIPLHHQQALSSTGVALNHIPAGVKDASDKKILVDMLLWAIDNPAPANLLLISGDRDFSNALHQLRMRRYNILLAQPPRASVPLVAAARDVWLWTVLASGGPPLTSVESSLLFNNGGFRVSNKGVSKLPVSEQAQPSQPTGSTSNAGDTKDHKTREKHVPRGSLQENRKNMLQHSSGATGESATTCRICNVVCDSFEKFTAHLSDIRHISQAAIVESRRAQASVSAKPIHQAVLVEPLLCKVCQISFTNNDTYKNHTYGKKHRNNLELQSGKSKNILVGPAEPSKEVLEKHNMNKKVMIESRAQANAEFVCLMCNVVCQSQIVFNSHLRGKKHANMLSQSEALIVSTKLQEKGVGEKEQPSETVAELQLQSQKAQEKQVLVDSKKLPEKGDEVKGQPKEMTALRNASAKYICRMCNVGCHSPIVFETHLRGQKHAANLNQSKDQALIDSKKLQEKGFGEKEQPRETIVEPQLQSQNAQENSKCFEKHVVMVNQSEVLINASKLEEKDAQEKAQPIESIAEPQSQSQNTQEHTKFFEKQNEELRKICGTLESSVKEPLPSTKDWVETLNKQIPNGEFFFGDLRSDFEVPREASECFDGIVKPVNLSKGETKHSWEAAFVASNGSQSSVSTNPLKEPEGLQPVWCQVCQISCNSKVAFASHTYGKKHRQNLESQSAKNETMSTGPGKLSKDYGEKTKKVSCKNQTTFDSQLKSQNHYTMAKELVEKAFVSAFEHVSALEQFSIVDSRTIREDTDQEKEATKEQTLVKMDGNGFRGAPEDKVELNQEKHREALEQFSIDSRIIREETDQEKEATEEQTLVKMDDLGFRGAPEDKVELKERHTVSENLVHRVFTEQNRESRIPNEPRGCLDVIPERVKLPPNVNVAKNLEDEQKHKPEPKAQEAENKSGGRKDLPGEAAKREEIKGQADNFWTRLWGKKY
InterPro domains: - IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [293-734]
- IPR003604: Matrin/U1-C-like, C2H2-type zinc finger (domain) [240-731]
- IPR013087: Zinc finger C2H2-type (domain) [243-724]
- IPR024768: Meiosis regulator and mRNA stability factor 1 (family) [10-444]
- IPR021139: NYN domain (domain) [12-148]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0009561 (megagametogenesis), GO:0016043 (cellular component organization), GO:0009559 (embryo sac central cell differentiation), GO:0048229 (gametophyte development), GO:0030154 (cell differentiation), GO:0010197 (polar nucleus fusion), GO:0006996 (organelle organization), GO:0009553 (embryo sac development), GO:0048284 (organelle fusion), GO:0006997 (nucleus organization), GO:0000741 (karyogamy)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Protocadherin alpha 2 (Q91Y17)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Sequence: MPSLRGGPEVRQCLLLLLPFLAAWEAGNGQLHYSVPEEAKHGTFVGRIAQDLGLELTELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVRDINDNPPRFPMTEKTIQFSESRSLDSRFPLEGASDADIGVNALLSYKLSPSELFFLDVQTSDELSQSLFLVLGKSLDREEDAEVKLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFPQSVYKVQLLENTANGTLVMKLNASDADEGSNSEIVYSLGSDVSSTTRTKFQIDPNSGEVRTKGELDYEERTSYEIQVIASDKGTPAMSGHCKISVKLVDINDNTPEVSITSLSLPVQENAPLGAVIALISVSDRDSGVNGQVTCSLSPHVPFKLVSTFKNYYSLVLDSALDREATADYKVMVTARDGGSPSLRATASVSVEVADVNDNAPVFAQPEYTVFVKENNPPGAHIFTVSAMDADAQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLQFQVTARDAGVPALGSNVTLQVFVLDENDNAPLLLPQGAVGVGGSVSELVPRSVGSGHVVTKVRAVDADSGYNAWLSYELQSTVGMRSLFRVGLYTGEISTTRALDEVDAPRQRLLVLVKDHGEPSLTATATVLVSLVENSQAPKTSSRALVDAAGQEASLVTVNVYLVIAICAVSSLLVLTLLLYTALRCSAMPTDGACAPGRPMLVCSSAVGSWSYSQQRRQRVCSGEGPPKTDLMAFSPSLSQGPESAEERQPPLEAEYLGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPANNQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
InterPro domains: - IPR050174: Protocadherin/Cadherin-related Cell Adhesion (family) [14-769]
- IPR002126: Cadherin-like (domain) [28-677]
- IPR031904: Cadherin, C-terminal catenin-binding domain (domain) [798-931]
- IPR013164: Cadherin, N-terminal (domain) [30-111]
- IPR015919: Cadherin-like superfamily (homologous_superfamily) [30-667]
- IPR020894: Cadherin conserved site (conserved_site) [230-563]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0005509 (calcium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhesion), GO:0098609 (cell-cell adhesion), GO:0098742 (cell-cell adhesion via plasma-membrane adhesion molecules), GO:0007156 (homophilic cell adhesion via plasma membrane adhesion molecules)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Gastric inhibitory polypeptide (Glucose-dependent insulinotropic polypeptide) (A1DPK4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Sequence: MKAAMFALVLICLGSVWPSAGSQPLDSSIIHSSPNDIQKLSRRYAESTIASDISKIVDSMVQKNFVNFLLNQREKKSEPALTEDPESHIFNDLLKKEFVMWIQSKGDTFKNQ
InterPro domains: - IPR000532: Glucagon/GIP/secretin/VIP (domain) [44-71]
- IPR039078: Gastric inhibitory polypeptide (family) [1-78]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0001664 (G protein-coupled receptor binding), GO:0071855 (neuropeptide receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0043010 (camera-type eye development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)