Protein: Heterogeneous nuclear ribonucleoprotein L2 (A8KC22)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MATQTARFYSEGGRATKRQKTENEGGMATEGYTDPHKTLPSLVVHVRGLVDGVLESDIVEALQEFGTISYVVLMPKKRQALVEYEDMNGSCNAVTYANDNQIYIAGHPAFVNYSTSQKISRPGDPDDARSVNNVLLLTIMNPIYPITSDVLYTICNNCGPVQRIVIFRKNGVQAMVEFDSVQSAQRAKASLNGADIYSGCCTLKIEYAKPTRLNVFKNDQDTWDYTNPSLGTQDMNANPNKRQRQPALLGDHPPEYGGYPGYPDESYGYEGRRMGPPMSAPRRGGASQRYSAQYGGPPPPPPGEYGAHADSPVIMVYGLDPVKINADRVFNIFCLYGNVERVKFMKSKPGAAMVEMGDCYAVDRAISHLNNNFLFNQKLNLCVSKQQAIMPGQSYELDDGTNSFKDYHGSRNNRFATPEQAAKNRIQHPSNVLHFFNAVPEATPEMFTRLCEEHGVKNPSNIKIFVAKGNSPDRSSSGLLEWESVNDAMEALAMINHNQMKNPNGPYPFTLKLCFSTAQHAN
InterPro domains: - IPR021790: PTBP1-like, RNA recognition motif 2 (domain) [132-209]
- IPR035005: hnRNP-L, RNA recognition motif 1 (domain) [40-119]
- IPR035979: RNA-binding domain superfamily (homologous_superfamily) [33-408]
- IPR034816: hnRNP-L, RNA recognition motif 3 (domain) [310-386]
- IPR055204: Heterogeneous nuclear ribonucleoprotein L, RRM domain (domain) [423-519]
- IPR006536: HnRNP-L/PTB (family) [40-520]
- IPR035008: hnRNP-L, RNA recognition motif 2 (domain) [129-228]
- IPR000504: RNA recognition motif domain (domain) [42-386]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [42-515]
Interaction partners: - Heterogeneous nuclear ribonucleoprotein H
- Heterogeneous nuclear ribonucleoprotein K
- Heterogeneous nuclear ribonucleoprotein U
- SUMO-conjugating enzyme UBC9-B
- RNA-binding protein FUS
- Heterogeneous nuclear ribonucleoprotein C
- Serine/arginine-rich splicing factor 2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0042221 (response to chemical), GO:0042330 (taxis), GO:0071840 (cellular component organization or biogenesis), GO:0032989 (cellular component morphogenesis), GO:0000902 (cell morphogenesis), GO:0009887 (animal organ morphogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0016043 (cellular component organization), GO:0006935 (chemotaxis), GO:0022008 (neurogenesis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0097485 (neuron projection guidance), GO:0032990 (cell part morphogenesis), GO:0048858 (cell projection morphogenesis), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0007411 (axon guidance), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0048812 (neuron projection morphogenesis), GO:0061564 (axon development), GO:0007409 (axonogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)