Protein: Adenosine deaminase RNA-specific (A0A8M1P8J0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm
Sequence: MSRGRGGNYKDSQRFSLPFRKGQPQFYSSTTTGQSRGPRVPSPSSLSGSSPHPSFYSSYSSGPGVPPRDHPFPPRHSDPSLWASPQHGSDQISDSNGVSFRQNQVQFLRGQSAQAPQFKAPQPRGSQSSSRGEEVSTEPIQYQTGYRDFKSNSYSFGRRNCYGRGQDNWQGEQNFGPKKRSGWNHPHQKGQYYSNQHYKQFWNARANDLSSGIYNLSFGDRVKRVDTSDTLSCSNSSSKVSSSSSSFRDSLYLTPEIHQQVCAFLTSLRPAETIQAKVLGKKLGLPKKIVNKVLYDLLKSNQVVKQGETPPLWRLCEESRESIREKDQTQSSKDLEKEPGQSPYINQKVGGDFTTTSTPSPSKIPIDADSDTSDESEDSEGDDSCEKLLADQDKKTLSPTVQSVTLSTMADSKDSKEKILQYLYEAGTGNALVIAKNLGLRSAKQVNPTLYALEKQGDVNRNTEVNPPTWELSAHRQEKMDRQRKAAATANQDVNSAATLSLEDDEIANVALVNFEPMEGGGKPLVEMLDNDNVFGNTEIDIPGLEPVSKASDLSSSTHRNFQPNQFPYYQETPSNGGEQSQWASDDIPEFLNTIRSEVAVSLAAPPPPTQSMESNRLQKLKEARSKNPVSGLMEFAQHLGYTCEFLLLEQSGPSHDPRFRMQVMLDGRRFPAAEGSNKKVAKKDAAAITLKILWKELDGGGGEEEEEPNIEGAGSTTDMADDMGGTDTPPQALSRSLPGGKNPVSVLMEHSQRSGHPIQFIKTGQEGPSHDPRFMFRVKVGERLFQEASAPSKKAARQLAAEEAVKELMGDGLLHLNKPPSSFCPMGDSESQPMFPACPSLPPLTAAELQAAHEAGVGDLINHLNNNAVSGLLEYARARGFAAEIRLVGQSGPSHEPKFTYQAKLGGRWFPAVCASNKKQGKQEAADAALRVLIGEAEKAARTGELMPELPVSGSTIHDQIAMLSHQRFNALTARIQHSLLGRKILATIVMRNGTDSLGKVVSLGTGNRCVKGEELSLRGDTVNDCHAEIISRRGFIRFLYSELMKHWESPGDETIFELAGDGKLKIKSDITFHLYISTAPCGDGALFDKSCSEAAELNGSGHMPLFENIKQGKLRTKVENGEGTIPVESSDIVPTWDGIQHGERLRTMSCSDKILRWNVLGLQGALLTHFIHPIYLHSITLGYLYSHGHLTRAVCCRLSRDGDTFKSSLPANFTLNHPEVGRVSVYDSTRHTSKTKESSVNWSQPDQYSVEVLDGTKGKLDSPKMEVSRVSKSNLFRLFHALCQRAGRADLLALQSYAHAKMAATSFQEAKRLFFLALSQHGYGAWIGKPLEEKSFEGEAKSFEPMGGSGDVQASGCVVDPNSFLSSENNNFLSAAQGF
InterPro domains: - IPR002466: Adenosine deaminase/editase (domain) [957-1339]
- IPR044456: ADAR1, first double-stranded RNA binding domain (domain) [627-697]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [242-483]
- IPR014720: Double-stranded RNA-binding domain (domain) [628-936]
- IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [246-481]
- IPR042371: Z-binding domain (domain) [250-476]
- IPR044457: ADAR1, third double-stranded RNA binding domain (domain) [867-937]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0032501 (multicellular organismal process), GO:0050793 (regulation of developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0048523 (negative regulation of cellular process), GO:0009892 (negative regulation of metabolic process), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0045595 (regulation of cell differentiation), GO:0031323 (regulation of cellular metabolic process), GO:0016043 (cellular component organization), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0060041 (retina development in camera-type eye), GO:0045664 (regulation of neuron differentiation), GO:0007399 (nervous system development), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0048880 (sensory system development), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0007423 (sensory organ development), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0043933 (protein-containing complex organization), GO:0051252 (regulation of RNA metabolic process), GO:0051253 (negative regulation of RNA metabolic process), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:0010468 (regulation of gene expression), GO:0022607 (cellular component assembly), GO:0001654 (eye development), GO:0065003 (protein-containing complex assembly), GO:2001141 (regulation of RNA biosynthetic process), GO:1902679 (negative regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0150063 (visual system development), GO:1903507 (negative regulation of nucleic acid-templated transcription), GO:0043010 (camera-type eye development), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045892 (negative regulation of DNA-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)