wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: 2-hydroxyacyl-CoA lyase (D6WWN7)
Organism: Tribolium castaneum (Red flour beetle)
Sequence: MEEIDGNAILAQALKEQGIEYVFGICGFPVIELSMALQTAGIHYIGMRNEQAACYAAQAIGYLTGVPGGVLVVSGPGLLHVCAGMANAQVNCWPVVVIGGSCPQDHEGIGGFQECYQVELARPYCKYSARPPSLALIPQHVEKAVRLATYGRPGAVYLDFPGNLLQARTTIDKIPKQYTAPEIPVIYPEPRKIDEAAALIMGAQRPLVIVGKGAAYARAEGQVRELVDSTNLPFLATPMGKGVVSDTNPNSIQPARSLALQRADVVLLLGARLNWILHFGRPPRYNPNVKVIQIDVCAEELNNSVKAAVAIQSDLKPAVGQLVQSLKRRNFTFSKNSDWWNDLNKKIQDNKRKVQEMTLDVSEPLNYYAVFHHLQEVLPQNPIIVSEGANTMDIGRAVLMNGLPRHRLDAGTFGTMGVGLGFAIAAALYCRHFEPKKRVICVEGDSAFGFSGMEIETMVRYKLPVIIVVVNNSGIYGGLPQEVYKDLQESGEVTKVTPPTTLFTSTHYEKMMTMFGRQGYHCTTIAELQKAVKEALKETEGPSIINVIISPSADRKPQDFNWLTESKL
InterPro domains: - IPR029035: DHS-like NAD/FAD-binding domain superfamily (homologous_superfamily) [187-354]
- IPR045025: TPP-binding domain containing protein HACL1-like (family) [2-567]
- IPR029061: Thiamin diphosphate-binding fold (homologous_superfamily) [3-555]
- IPR011766: Thiamine pyrophosphate enzyme, TPP-binding (domain) [388-547]
- IPR012001: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (domain) [6-119]
- IPR012000: Thiamine pyrophosphate enzyme, central domain (domain) [193-322]
Interaction partners: - Branched-chain-amino-acid aminotransferase
- Peroxisomal targeting signal 1 receptor
- (S)-2-hydroxy-acid oxidase
- 2-oxoisovalerate dehydrogenase subunit alpha
- Probable hydroxyacid-oxoacid transhydrogenase, mitochondrial
- Succinyl-CoA:glutarate CoA-transferase
- Alpha-methylacyl-CoA racemase-like Protein
- Malic enzyme
- Malic enzyme
- Citrate synthase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016830 (carbon-carbon lyase activity), GO:0016832 (aldehyde-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0009056 (catabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044282 (small molecule catabolic process), GO:1901575 (organic substance catabolic process), GO:0006082 (organic acid metabolic process), GO:0044248 (cellular catabolic process), GO:0016054 (organic acid catabolic process), GO:0043436 (oxoacid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0046395 (carboxylic acid catabolic process), GO:0043649 (dicarboxylic acid catabolic process), GO:0043648 (dicarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0042579 (microbody), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005777 (peroxisome)
Protein: Hormone-sensitive lipase-like Protein (D2A0J0)
Organism: Tribolium castaneum (Red flour beetle)
Sequence: MTDQDNAVNGLEPKEASASNIEVLKDLCENNANFFAKDTSENGQRLYISFMGIRENLDEISQKMARIASEAPRFDFDESTPGNGYRSFLSVANSAIDYGIALNKKICLKRASAFFRKSQLTKDVESCAHLIASLDTCFKHLETLISWSSAGNLFPDEEHSPQELLSNYEDINQYCFYGRCMGFQFCESLRNILQFISMSMAIFSEIYYNQGSFFAKATTSLMATSKYVNDPEQRARRIVNISQNADVNFCKAFWFLSENELMTNMPYVVAPSVAVSRIISLPPEPFTLEVDGREIDVPVPSSHIGRKPVQVRLISHEVHEGMIGEASNKYKSKPPARGLIIHCHGGGFVAQSSLSHECYLREWAKQLKVPILSIDYSLAPEAPFPRALEEVTYAYCWALKNCQLLGSTGERIIGAGDSAGANLLLSTTLKCLNLGIPPPMGLFVAYVPTLVNFVPSPSRLLCMMDPLLPFGFMMRCLKAYACPDNKKVENCDQTSDTESFEEISESDLMELQAHKSPVSETSDTLTYGSLNSGEDDRNKDIDLQSSNIENSQKYVSDFLEKYVLDSDTETDGTRVPVLKHESATSSQSIDDSLQTKVSSFVSNLKWRFNSWIAQKAQVGVDFMVPRSASAAEKYLDLDRQGNLLDEFKFTVPEDPFLSPFCAKDEDLERFPPVRVLTVHLDPCLDDCVMFSKRLKQLNKNVHLDILSGLPHGFLNFSLISKEAYEGSKLCVKRINELLNLDNLPPLQ
InterPro domains: - IPR010468: Hormone-sensitive lipase, N-terminal (domain) [21-322]
- IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [309-741]
- IPR013094: Alpha/beta hydrolase fold-3 (domain) [340-714]
Interaction partners: - Tryptophan 2,3-dioxygenase
- Acyl carrier protein
- NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
- Acyl-CoA synthetase family member 4 homolog-like Protein
- 1-acylglycerol-3-phosphate O-acyltransferase ABHD5-like Protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0006629 (lipid metabolic process), GO:0006638 (neutral lipid metabolic process), GO:0046486 (glycerolipid metabolic process), GO:0006639 (acylglycerol metabolic process), GO:0006641 (triglyceride metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Glutamate-rich WD repeat-containing protein 1 (D6WH34)
Organism: Tribolium castaneum (Red flour beetle)
Subcellular location: Nucleus
Sequence: MSDQEMDVVDDNESENEEAMQEENEGNTEKPSEVYLPTKPLEEGEELVCDQSAYVMLHQAQTGAPCLSFDIIKDSLGESRDTYPLTAYIVAGTQAPQTHVNNVIVMKLSNLHKTNKGEDDDDDDDEESDDDEVSKNPKMAGALIKHQGCVNRIRSTVINNKIIAASWSELGRVNLWDLSQQLEAVDNDQLLSRYNKENKANSVKPLFTFTGHQQEGFAMDWCSTNVGVLATGDCKRDIHIWKPASGASWQVDQRPLVGHTNSVEDLQWSPNERSVIASCSVDKSIRIWDTRAQPSKACMLTAENAHESDVNVISWNKNEPFIVSGGDDGFLHIWDLRRFQQKTPVATFKHHTEPVTTVEWHPTDSAVFISGGSDNQVALWDLSVEKDDESGSEEVDGIPPQLLFIHQGQNNIKELHWHPQLPGVIISTAESGFNIFRTISV
InterPro domains: - IPR020472: PAC1/LIS1-like, WD-40 repeat (repeat) [276-382]
- IPR051972: Glutamate-rich WD repeat-containing (family) [9-441]
- IPR022052: Histone-binding protein RBBP4-like, N-terminal (domain) [45-112]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [128-436]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [3-438]
- IPR001680: WD40 repeat (repeat) [136-437]
- IPR019775: WD40 repeat, conserved site (conserved_site) [276-336]
Interaction partners: - Ribosome biogenesis protein BOP1 homolog
- Protein Peter pan-like Protein
- Ribosomal L1 domain-containing protein CG13096-like Protein
- Ribosome assembly factor mrt4
- Nucleolar complex protein 2 homolog-like Protein
- Periodic tryptophan protein 1 homolog-like Protein
- Bystin-like Protein
- MKI67 FHA domain-interacting nucleolar phosphoprotein-like
- RNA helicase
- ATP-dependent RNA helicase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0003006 (developmental process involved in reproduction), GO:0007389 (pattern specification process), GO:0009791 (post-embryonic development), GO:0009799 (specification of symmetry), GO:0048608 (reproductive structure development), GO:0003002 (regionalization), GO:0090567 (reproductive shoot system development), GO:0048731 (system development), GO:0009855 (determination of bilateral symmetry), GO:0048367 (shoot system development), GO:0061458 (reproductive system development), GO:0009953 (dorsal/ventral pattern formation), GO:0009908 (flower development), GO:0048262 (determination of dorsal/ventral asymmetry)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Serine/threonine-protein kinase receptor (A0A139WM83)
Organism: Tribolium castaneum (Red flour beetle)
Subcellular location: Membrane; Single-pass type I membrane protein
Sequence: MPPKTHRNNMARTSLLVFCCAVFWLSRLDNGVQALKCKCDNCKETNYTCQTDGYCFTSTYLSKSGGVEHNYRCLDKRQFFPPEEPRWCHSRPTTEYVQRCLDRSLQVPHNNPLLCHRQNPLNSEFVMECCKNEDYCNVHLSPRLMQKPQAPKFSNFTTAEIVLMSVIPTMLLCFIGVGVYYFYKTKHKRGGLHHHLRHGEDSIEAPDHPILKGVSLQHMIEMTTSGSGSGLPLLVQRSIARQIQLVEIIGQGRFGEVWRGRWRGENVAVKIFSSREERSWFREAEIYQTVMLRHDNILGFIAADNKDNGTWTQLWLITDYHEYGSLFDFLGRNTLDTTGMIRMALSIATGLAHLHMDIMGTQGKPAIAHRDLKSKNILVKSNFTCAIGDLGLAVRHDATTDTVDIPLNNRVGTKRYMAPEVLDETMNVNHFDSFKRADVYALGLIFWEIARRCNVGGIYDEYQLPFYDAVPSDPTIEEMRRVVCVDKQRPNIPNRWQSCEALRVMLKLMKECWYHNATARLTALRIKKTLSNFRTSEELKM
InterPro domains: - IPR045860: Snake toxin-like superfamily (homologous_superfamily) [34-140]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [367-379]
- IPR001245: Serine-threonine/tyrosine-protein kinase, catalytic domain (domain) [243-529]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [223-530]
- IPR017441: Protein kinase, ATP binding site (binding_site) [249-270]
- IPR003605: GS domain (domain) [214-243]
- IPR000472: Activin types I and II receptor domain (domain) [35-138]
- IPR000719: Protein kinase domain (domain) [243-533]
- IPR000333: Ser/Thr protein kinase, TGFB receptor (family) [26-536]
Interaction partners: - Serine/threonine-protein kinase receptor
- Protein decapentaplegic
- Mothers against decapentaplegic homolog
- Glass bottom boat2
- Dawdle
- Serine/threonine-protein kinase receptor
- Myoglianin
- TGF-beta family profile domain-containing protein
- E3 ubiquitin-protein ligase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009719 (response to endogenous stimulus), GO:0071495 (cellular response to endogenous stimulus), GO:0070848 (response to growth factor), GO:0071559 (response to transforming growth factor beta), GO:0071363 (cellular response to growth factor stimulus), GO:0071560 (cellular response to transforming growth factor beta stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Uncharacterized protein (D6X0W5)
Organism: Tribolium castaneum (Red flour beetle)
Sequence: MLILLLVPLLTGASATSNVTIDEIPETYLNLSAGNSLWTALLKNCRQPTMACVEKTVYEYLKRTVETREDLHVVPFVKMKRNQVDYDRISGPEIGDWDEEEPESSLEAMSRDLHGKSVKFLMTHDMEVQLPETMFQGSVLKISPRAFEGNGALVKLEIQPKEVQGIAEGRLFKKLKNFISEKLIYALLAILLVIKLLAAKFMFFMPMAVGAVTAKKLLIKVLLFLFPALHHFFKLCAYVPHGTKYHHHKHHISHIHHVAPHKHHHHGHHHPHPHDSVEVIHPHAEGPPVVEGPWHHGGASLHHSIEIEEPHKTYYKPHEQELEYYSGGPHLSHHFINHRQDSQEDNEVQPAQGHRNKKPSNRPLTPSEIEAMVLKAEKEAKLKVRLQQERHRIQEENARLQEQLKLALKIQEKLKQQAAVVKAKLPVPPSTNLQTPASEQKQVYSAKVKQPEVVQPETKKEPTPFETALHQAAAITYDPFYSPILEKIDKILVGLGFNEEPCRERLICSMYKNPVKFSPHSNLLSAELSRDSKELQKPTTTNAAVIRFYRYVQAARDGQDKRECLRLYPSCSINTEQ
InterPro domains: - IPR006631: Protein of unknown function DM4/12 (family) [485-571]
- IPR012464: Protein of unknown function DUF1676 (family) [2-332]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0046907 (intracellular transport), GO:0045184 (establishment of protein localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0008104 (protein localization), GO:0015031 (protein transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Protein neuralized (D6WC61)
Organism: Tribolium castaneum (Red flour beetle)
Function: Involved in neurogenesis. Interacts with other neurogenic proteins in the specification of the neuroblast versus epidermoblast cell fate
Subcellular location: Nucleus
Sequence: MGISENKACNCKADKVKGDDIFSPLKGKMKVLKKIKRRMGLASRSGSNGGGTNNLPPLLFHNVHGENIRISRDGTIARRVESFCKGIAFSSRPVKVNEKICIKFLEISNNWSGVIRFGFTFNDPSSLRYGLPKYACPDLTNKPGYWAKALPERFCSQNTVLFYYVTSTGDVHFGINGEEKGIFFSSVETRGPLWALIDVYGNSTAIEFVDIRHQLNNSRRNIASNSCENPPEDVDRIIYRMEQVHIQQRDNEDLSLPLLRYQPPQLNFNPMMLHRTRGRNVRFGSTRNNAYRTDTEFCQGYVFTARPLQLGERVVVQILATEPMFQGCLGLGLTSCDPATLQSGDLPDDSNFLLDRPEYWVLSRDFARNLNKGDEISYCISPTGEVQISRNGDSPLVVIHVDQTLRLWAFFDIYGSTQRIRVLSCPAPVSPVRNFERRIISPSATESMNSINSQSEIRRNSVMQSNSRLCCVAPADIQVQPATNGGAVLSVILPPAHANFLNQQTQTVHVNHQNSVHTQNGHGPHPSYVGPAIPISPVVAPVPNLQPTGTMISTCSSTYVEPISDSSSYSTPLGWAEVNGATVGTGTECTICYENSIDAVLYMCGHMCMCYECALQQWRGKGGGHCPLCRAVIRDVIRTYKS
InterPro domains: - IPR001841: Zinc finger, RING-type (domain) [589-630]
- IPR043136: B30.2/SPRY domain superfamily (homologous_superfamily) [59-424]
- IPR037962: Neuralized (family) [51-642]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [579-642]
- IPR006573: Neuralized homology repeat (NHR) domain (domain) [55-425]
Interaction partners: - RING-type E3 ubiquitin transferase
- RING-type E3 ubiquitin transferase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0008289 (lipid binding), GO:0005515 (protein binding), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity), GO:0035091 (phosphatidylinositol binding), GO:0061659 (ubiquitin-like protein ligase activity), GO:0061630 (ubiquitin protein ligase activity), GO:1901981 (phosphatidylinositol phosphate binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048870 (cell motility), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0016477 (cell migration), GO:0072359 (circulatory system development), GO:0007507 (heart development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle)
Protein: TAR DNA-binding protein 43 (D6WYQ8)
Organism: Tribolium castaneum (Red flour beetle)
Subcellular location: Mitochondrion. Nucleus
Sequence: MSVEYLQVAEDEGEEPIELPTEDDGTLLLSTLAAQFPGSSGLKYRNPETKAMRGVRLSEGRLHPPPEIGWGTQIFYCVFPKENKRKSDDNLENSTAKTKRMETKLRCTDLIVLGLPWKTTEQNLREYFETFGEVLMAQVKKDPKTGQSKGFGFIRFASYESQMRVLAQRHMIDGRWCDVKVPNSKEGLIQQVPCKVFIGRCTEELTADDLREYFGKYGEVTDVFIPKPFRAFSFVTFLDPEVAQSLCGEDHIIKGVSVHVSNAAPKSETRGGGYGGGGPRGANHGNNRSGPGPDGPGMYQQRYNPGPNQGNWSNQGPRGNIDMPNLQALGITGQGQQGSNQQSCNPLGLGLNLSALPMNPALVAAALNQAGWGLIGNLQNQPEPNFNQGFNNGPNNNSGNTPNGSNQGGSSNPGFLSWINQGGGQNQDGGQWPRPPPQQAQENKGFLKYD
InterPro domains: - IPR000504: RNA recognition motif domain (domain) [108-265]
- IPR035979: RNA-binding domain superfamily (homologous_superfamily) [108-296]
- IPR041105: TAR DNA-binding protein 43, N-terminal (domain) [5-79]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [108-269]
Interaction partners: - Lesswright
- Serine-arginine protein 55-like Protein
- Uncharacterized protein
- Heterogeneous nuclear ribonucleoprotein K-like Protein
- Microtubule-associated protein
- RRM domain-containing protein
- Ribonuclease 3-like Protein
- Putative ATP-dependent RNA helicase DHX34-like Protein
- Survival of motor neuron-related-splicing factor 30
- Small nuclear ribonucleoprotein Sm D3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003723 (RNA binding), GO:0003697 (single-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0009408 (response to heat), GO:0009266 (response to temperature stimulus), GO:0035556 (intracellular signal transduction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Neurogenic protein big brain-like Protein (D6W7H3)
Organism: Tribolium castaneum (Red flour beetle)
Subcellular location: Membrane; Multi- pass membrane protein
Sequence: MAEERVNLSSEPSIDYHIVTLFEKLEALRNDKPNSQFTSKLSIKVEVRTLEFWRSVISECIASFVYVFVVCGAKAGAFDGGSATTSLGVLSTALAAGFAMISLTQCFGHISGAHINPAVSLAMGITKNISLLRTTMFIVAQCGGAIAGAAFLYGVSIPRTQEDLPMSLPIKDGPWERFGNEFILTFVVVLAYFVSMDAQRRWMGMSAITIGATYSACSFVSPMPHLNPARSLGPSFVLKKWDNHWVYWLGPIIGGVAAGLIHEYIFNSKRSKRQNSSSDGDSSSIQSDEDTYDDLDKPNAPKYQESTYNSYRAGAPNGPTGYCPSLTSASLYSTPATKLERVESLYGGTRSLYCKSPPLTRANLNRSQSVYTKNSGGPRDILPKPGPLVPTQSLHSIKLNQQTHVHNQNLQNQLQQRSESVYGVRGNPPGSLSRPETEKSAYPSKNSAPNSEESKKNSKINRPESMYGIMSLQRRGQSAQSDDSSYGSYHGPAPRNNTYHSNTSGFQNKAGSVASYVSRNAGSAEGRPPPSANQLLTTTGNPTNSYHHHQHSPSSQY
InterPro domains: - IPR023271: Aquaporin-like (homologous_superfamily) [23-281]
- IPR034294: Aquaporin transporter (family) [23-448]
- IPR000425: Major intrinsic protein (family) [46-265]
- IPR022357: Major intrinsic protein, conserved site (conserved_site) [114-122]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015267 (channel activity), GO:0005372 (water transmembrane transporter activity), GO:0015250 (water channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0021700 (developmental maturation), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0009791 (post-embryonic development), GO:0048316 (seed development), GO:0048608 (reproductive structure development), GO:0010431 (seed maturation), GO:0048731 (system development), GO:0071695 (anatomical structure maturation), GO:0061458 (reproductive system development), GO:0010154 (fruit development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Striatin-interacting protein 1-like Protein (D6W7U6)
Organism: Tribolium castaneum (Red flour beetle)
Sequence: MDPNGNGKRGLPRLREIIRRQRQDSDGGGTDSPDLDFIYDDTDTHPNEIAELYSYTEQPELALNVKAFEDQMEQYNLPPSWQRLSLEQRKSVVMKLLDQLEVSSKPLRMRAARCILYIAQGCWAEMQSDAEQQQWARVNVMLLYQLGVFSAFTDLLNIEIENSTAAHVAMRKIAVSLADSQDLRVILSVLYTITEVIRNEKYSGSTEYQSDVESFCSDLANSYDDELLIVKLLGMVTRFCSGAAPHFPMKKVLLLLWKLILVTLGGMTVLKDLKDEKREKAGLPRLDEDTMEIAKTMRASSPPASASDLLEAQNQKRNTRPFRRNLMKQSSLDDHESLGMELDATLVGGDNGDELGELSEYDDRRPPENSENNQMYSNYQNRPTSPPLQSSLVVPRGLPWKPKVRQKDIDLFLDTARLKFVGYSLQGDRDSLAGLPLPIHEGVKTLKEHVYTSLAELQIQKEEEIARNPLSTSEGEIEMTPTEILYQAMLPNLPQYMIALLKILLAAAPTSKAKTDSINIMADVLPEEMPMTVLQSMKLGIDVNRHKEIIVKAVSAILLLLLKHFKLNHIYQFEFMSQHLVFANCIPLVLKFFNQNIMAYVGAKNVIPILDFPSCVIGDQPELTAESLEIGDSAPFSWRNMFSCINLLRILNKLTKWKHSRIMMLVVFKSAPILKRTLKVRHAMTQLYVLKLLKMQTKYLGRQWRKSNMKTISAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRASVDRFNNRRYTQANQDSEFAPVDNCLNSVLGTTYDLSESFKQHYQLWLEQEVYGNTIEWEELLLNQTI
InterPro domains: - IPR012486: Far11/STRP, N-terminal (domain) [32-331]
- IPR021819: Far11/STRP, C-terminal (domain) [436-793]
- IPR040185: Far11/STRP (family) [11-812]
Interaction partners: - Striatin-3-like Protein
- Uncharacterized protein CG10915-like Protein
- MOB kinase activator-like 4
- Programmed cell death protein 10-like protein
- Serine/threonine-protein phosphatase
- Sarcolemmal membrane-associated protein-like Protein
- Circulating cathodic antigen homolog-like Protein
- non-specific serine/threonine protein kinase
- Protein phosphatase PP2A regulatory subunit A
- Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit-like Protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0051239 (regulation of multicellular organismal process), GO:0044057 (regulation of system process), GO:0090257 (regulation of muscle system process), GO:0006937 (regulation of muscle contraction), GO:0006940 (regulation of smooth muscle contraction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)