Protein: Uncharacterized protein (Q57ZX9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000256|ARBA:ARBA00004120}.
Sequence: MHLYLTKRVAIPSTVAVTAVAWNEEQGWLAVGGKGGLLKVLKIDGGGSQRGGLAMNQTLEGHETDVSVVAWNHQYRKLTSSDAGGQIIVWMLHKGMWLEEMINNRNKSTVRDLAWSVDGTKVCIVYEDGAVILGGVDGNRLWGKDLKCELTNVTWSPDDRYILFGTKSGDVQMHDSATGHLVNQVAITHQANKVPLAGLEWSSAWVDRPEPLPSLAVCYKNGRIHLLRGITDHEARVVEAGINVTGIAWNPQGTMLAVCGVPATGGASGDGGTSAQGGATGGDAGADGSASSVLTLIYNGDGVHMRTLRMNGKFCGGITWEGDGLRVAVAVDAAMYFANVRCDYKYAYFHKTVVFAYNRPDRTDSSVMFWNTRNNERVIRHIRGLLHIHACRNACLIVNAPGEERCCIVQLVNAIGCPIESRMLDMEPIVSGLNSSHVVVADEENIYIWQFRDPSVVVDALDPVSVQMSRRETHDRVVHVDDFVRADTPSALTTQTALTNDLICTVCLSEDFLFVARESGLLQLYRFNPLQLVGKAVLPCRPQSIAVNCNSTRLVLIDVVGVMRMFHIDPTTMSLAPSKLVPQPGFERKDVWNVQWAQDDPEMLAVMERSRLHIYHGTESEEPITCSTHICKFRSLKVRSLLLDELKQDPERPRREYVIDHDTRALRDAREVMQTASTRDALRYMDEHSHPKLWSLFAEHALAQLDFDSAELAFIRCGDYPAIQFVKRIKTLDDPQKQRAEIHTYYHRFDQAEKIYKDIDRKDLALELRYRLGDWFRVVQLVQEGGGDESHMRRAWENIGDFYADRQKWTKAAQYYSQSQQLHKLAHILFLQEDYDLLVQLIQNAEHDRELLLKLGEMLLSVGLGEEALRAYLAAGEPRLAVESCTQLNQWDCVMAVAEEYKLTDVSKQLGRHATRLVDSGRLSEAIGLYRKAGQHDEAARLLAGLGQRAATTNPLSAKKFYVLSALEVEKYRKKKMTLSGNGTAAVEALLDVEQSGKGQERAFDAAWRGAEAYHFFLLCQQHILNRNLVYALNVAMRLMDYDDIISPVDSYSLIALTAYLAKNYSICSKAFTRLEAAEQMDEQSQSEGGEARGAVQLQMMDMIADLDVSCRTKVGHGVGPAGGGAGGVSGTTRLDGTTTSLQLTNPSKGAVSAIQMTYPTVTLTEPRRRFADLASKIFTQHKPEDNFIDRVKCHKCEAHNKEWASACVRCQQPFHVCIYSGRSITSEEFWQCSVCHHRLLDVETDRFRNCPLCHTPLRH
InterPro domains: - IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [749-877]
- IPR056158: IFT121, second beta-propeller domain (domain) [346-660]
- IPR001680: WD40 repeat (repeat) [5-175]
- IPR057361: WD repeat-containing protein 35, TPR repeats (repeat) [905-971]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [16-619]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [6-641]
- IPR056157: IFT80/172/WDR35, TPR domain (domain) [693-782]
- IPR057979: IFT121-like, TPR repeats (domain) [1005-1087]
- IPR017233: WD repeat protein 35 (family) [1-1260]
- IPR056159: IFT121/TULP4, N-terminal (domain) [1-341]
- IPR056170: IFT121-like, zinc finger domain (domain) [1217-1258]
Interaction partners: - Intraflagellar transport protein 122 homolog
- Intraflagellar transport protein 140
- WD repeat-containing protein 19
- Uncharacterized protein
- Intraflagellar transport protein 80
- IFT80/172/WDR35 TPR domain-containing protein
- Intraflagellar transport protein IFT88, putative
- Intraflagellar transport protein A1
- Intraflagellar transport protein 56 homolog
- Intraflagellar transport protein 57/55
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0009987 (cellular process), GO:0051641 (cellular localization), GO:0031503 (protein-containing complex localization), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0007017 (microtubule-based process), GO:0042073 (intraciliary transport), GO:0007018 (microtubule-based movement), GO:0044085 (cellular component biogenesis), GO:0046907 (intracellular transport), GO:0006810 (transport), GO:0051649 (establishment of localization in cell), GO:0016043 (cellular component organization), GO:0010970 (transport along microtubule), GO:0030030 (cell projection organization), GO:0030705 (cytoskeleton-dependent intracellular transport), GO:0035721 (intraciliary retrograde transport), GO:0035735 (intraciliary transport involved in cilium assembly), GO:0006996 (organelle organization), GO:0099111 (microtubule-based transport), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0044782 (cilium organization), GO:0120031 (plasma membrane bounded cell projection assembly), GO:0060271 (cilium assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0030990 (intraciliary transport particle)