wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Bleomycin hydrolase (EC 3.4.22.40) (A8JV24)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|PIRNR:PIRNR005700}.
Sequence: MKNYNLDEFEFSQAFLFYWDKIERCNYFLNNVVKTAQRGEKVDGRLVSFLLLDPTSDGGQWDMLVNLITKHGLMPKKCFPESFSCESSLRMNAILKSKLREYARNLRVLMEKNPTDEEIACKIQEQMAEIYKVVGICLGIPSETFTWEYYDKSKNYQSIGPVSSLEFYERYVKPHFNVEDKVCLVTDPRPTSSYDQAYTVDCLGNVVGGRPVLYNNQSVELLLAVVTKSLKAGEAVWFGCEVSKRFASKQGIEDVDVHDFKLVFDIDIQTTFSKADRLIYGESAMTHAMVFTAVSVDKSGVAQKLRVENSWGEDRGEKGYLVMNADWFREFGFEVVVDKKYVPEDVLRVFDMDPIVLPAWDPMGTLAQ
InterPro domains: - IPR004134: Peptidase C1B, bleomycin hydrolase (family) [1-368]
- IPR038765: Papain-like cysteine peptidase superfamily (homologous_superfamily) [2-366]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008234 (cysteine-type peptidase activity), GO:0019783 (ubiquitin-like protein peptidase activity), GO:0101005 (deubiquitinase activity), GO:0004843 (cysteine-type deubiquitinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0070647 (protein modification by small protein conjugation or removal), GO:0032446 (protein modification by small protein conjugation), GO:0016567 (protein ubiquitination), GO:0000209 (protein polyubiquitination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Armadillo repeat-containing protein LFR (Protein LFR ortholog) (OsLFR) (Q6YTW6)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Plays critical roles in both embryo and endosperm development. Required for free nuclei division and cellularization in early endosperm development, by preventing premature cell death in the endosperm. Involved in the regulation of pattern formation and organ differentiation during embryogenesis, by regulating genes involved in the early stages of seed development.
Subcellular location: Nucleus {ECO:0000269|PubMed:32808364}.
Sequence: MSHVRSAPAGKSGGGGGSTPAKRGRPFGSTTGSGAAAAAAAAAIGDAAAPAALVGPSLQVLTALSDQNNKRIVLALQSGLKSEILWALNALTVLSFKEKDDLRRDTTPLAKVPGLLDALLQVIDDWRDIAMPKDHTKPPRVRTLGVNTTLSGFGHENVEKVYSDTTTPSDDQTKTADSTVTKKRSAGFLFDEEGLFNVDDEGRTEKQQCAVAASNIIRNFSFMPENETVMVQHRHCLETVFQCLEDQNTEDDELITNMLETLVNLAPVLDLRIFSSSKPSFIKITEKRAVQAIMGMLASSIRVWHCAAAELIGRLIINPDNEPFLLPAIPQIYKRLVDLLSVPAVDAQAAAISALYNVAEVNMDFRLKLASERWAVDRLLKVVKTPHPVPEVCRKASMIVESLVSEPQNRMHLLVHENTFAEILTSEGKYSDTFARILYELTARPSNKVTAGQAIWGNIN
InterPro domains: - IPR016024: Armadillo-type fold (homologous_superfamily) [81-414]
- IPR011989: Armadillo-like helical (homologous_superfamily) [202-449]
- IPR021906: SWI/SNF-like complex subunit BAF250/Osa (family) [121-443]
- IPR033388: SWI/SNF-like complex subunit BAF250, C-terminal (domain) [209-240]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0003006 (developmental process involved in reproduction), GO:0009791 (post-embryonic development), GO:0099402 (plant organ development), GO:0090567 (reproductive shoot system development), GO:0048731 (system development), GO:0048608 (reproductive structure development), GO:0048437 (floral organ development), GO:0048438 (floral whorl development), GO:0048653 (anther development), GO:0048443 (stamen development), GO:0048367 (shoot system development), GO:0061458 (reproductive system development), GO:0048466 (androecium development), GO:0048827 (phyllome development), GO:0009908 (flower development), GO:0048366 (leaf development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Hypoxia up-regulated protein 1 (O46067)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Endoplasmic reticulum lumen {ECO:0000256|ARBA:ARBA00004319}.
Sequence: MKLVLLLSALLAGIALSQGAAVMSVDLGSEWMKVGVVSPGVPMEIALNRESKRKTPAILAFRDGTRTIGEDAQTIGIKDPNSAYGYLLDLLGKTIDNPIVDLYRKRFPYYNIVGDPERNTVVFRKSDTDEFSVEELVAQLLVKAKQFAQESVQQPITECVLTVPGYFGQAEREALLSAAQLANLKVLQLINDYAAVALNYGVFHRGEINETAQYFLFYDMGAYKTSAAVVSYQLVKDKQTREINPVVQVLGVGYDRTLGGLEIQLRLRDYLAQEFNALKKTKTDVTTSPRALAKLFKEAGRLKNVLSANTEFFAQIENLIEDIDFKLPVTREKLEQLCEDLWPRATKPLEEALASSHLSLDVINQVILFGGGTRVPRVQETIKAVIKQELGKNLNADESATMGAVYKAADLSAGFKVKKFVVKDATLFPLQVSFERDPGDGAAVKQVKRALFALMNPYPQKKVITFNKHTDDFEFYVNYADLDRYSKEEIAALGSLNVTKVQLKQVKELLEKSKKELVDNKGIKAYFYLDDSGIFRCTGVEYVYEKQKPEDDADEDSTLSKFGSTLSKLFTKEGEEKKDNSEQEEAANAGEEPSKSEDNEKAKEEDASKEQKSEESTKQDTEAKNETIKLVTVKSPVTYESQTQFVVPLVGSAYDQSVAKLAAINKAEEQRVRLESAFNALEAHIIEVQQKLDEESYAKCATAEEKEKLLAECSTLGEWLYEDLEDPKAEIYEEKLAQLKKLSNVFLARHWEHEERPEAIKALKGMIDGAEKFLVTGRNLTKDTNPEKDVFTQVEIDTLDKVITETNAWLKTETAAQKKLAKNADIRLTVKDITDKMSLLDREVKYLVNKIKIWKPKVKPAAEKEKKKEEEVVASGSGDDTKSEDAEQQQEQATKEEQQEQEPVDEITPTPAEEETKTPHSEL
InterPro domains: - IPR029048: Heat shock protein 70kD, C-terminal domain superfamily (homologous_superfamily) [652-761]
- IPR013126: Heat shock protein 70 family (family) [21-896]
- IPR018181: Heat shock protein 70, conserved site (conserved_site) [366-380]
- IPR029047: Heat shock protein 70kD, peptide-binding domain superfamily (homologous_superfamily) [416-629]
- IPR043129: ATPase, nucleotide binding domain (homologous_superfamily) [22-409]
Interaction partners: - Endoplasmic reticulum chaperone BiP
- Nucleotide exchange factor Sil1
- Heat shock protein 83
- Calreticulin
- LD25575p
- RE14391p
- Heat shock protein 83
- GrpE protein homolog, mitochondrial
- Protein disulfide-isomerase A6 homolog
- DnaJ-like-2, isoform A
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0097367 (carbohydrate derivative binding), GO:0005515 (protein binding), GO:1901265 (nucleoside phosphate binding), GO:0051082 (unfolded protein binding), GO:0043168 (anion binding), GO:0000166 (nucleotide binding), GO:0032553 (ribonucleotide binding), GO:0035639 (purine ribonucleoside triphosphate binding), GO:0032555 (purine ribonucleotide binding), GO:0017076 (purine nucleotide binding), GO:0005524 (ATP binding), GO:0032559 (adenyl ribonucleotide binding), GO:0030554 (adenyl nucleotide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0006950 (response to stress), GO:0008340 (determination of adult lifespan), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:0035966 (response to topologically incorrect protein), GO:0006986 (response to unfolded protein)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0012505 (endomembrane system)
Protein: Zinc-alpha-2-glycoprotein (Zn-alpha-2-GP) (Zn-alpha-2-glycoprotein) (Q63678)
Organism: Rattus norvegicus (Rat)
Function: Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers.
Subcellular location: Secreted.
Sequence: MVPVLLSLPLLLGPAVLQETGSYSLIFLYTGLSRPSKGLPRFQATAFLNDQAFFHYNSNSGKAEPVEPWSHVEGMEDWEKESQLQRAREEIFLVTLKDIMDYYEDSTGSHTFQGMFGCEITNNRSSGAVWRYAYDGEDFIEFNKEIPAWIPLDPAAANTKLKWEAEKVYVQRAKAYLEEECPTMLKKYLTYSRSHLDRTDPPTVKITSRVAPGRNRIFRCLAYDFYPQRISLHWNQASKKLASEPERGVFPNGNGTYLSWMEVEVPPQNRDPFVCHIEHKGLSQSLSVQWDEKSKV
InterPro domains: - IPR011162: MHC classes I/II-like antigen recognition protein (homologous_superfamily) [21-198]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [202-291]
- IPR050208: Antigen-presenting and immune regulatory MHC class I-related (family) [18-288]
- IPR011161: MHC class I-like antigen recognition-like (domain) [21-196]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [199-293]
- IPR007110: Immunoglobulin-like domain (domain) [202-287]
- IPR037055: MHC class I-like antigen recognition-like superfamily (homologous_superfamily) [20-198]
- IPR001039: MHC class I alpha chain, alpha1 alpha2 domains (domain) [77-192]
- IPR003597: Immunoglobulin C1-set (domain) [213-285]
Interaction partners: - Prolactin-inducible protein homolog
- Beta-2-glycoprotein 1
- Histidine-rich glycoprotein
- Haptoglobin
- Fetuin-B
- Inter-alpha-trypsin inhibitor heavy chain 4
- Afamin
- Long-chain fatty acid transport protein 2
- Serum amyloid P-component
- Apolipoprotein A-II
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0033218 (amide binding), GO:0005515 (protein binding), GO:0042277 (peptide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0002376 (immune system process), GO:0006955 (immune response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005615 (extracellular space), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005576 (extracellular region), GO:0005794 (Golgi apparatus), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: cDNA, FLJ94397, highly similar to Homo sapiens uroplakin 1B (UPK1B), mRNA (B2R9H7)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MAKDNSTVRCFQGLLIFGNVIIGCCGIALTAECIFFVSDQHSLYPLLEATDNDDIYGAAWIGIFVGICLFCLSVLGIVGIMKSSRKILLAYFILMFIVYAFEVASCITAATQRDFFTPNLFLKQMLERYQNNSPPNNDDQWKNNGVTKTWDRLMLQDNCCGVNGPSDWQKYTSAFRTENNDADYPWPRQCCVMNNLKEPLNLEACKLGVPGFYHNQGCYELVSGPMNRHAWGVAWFGFAILCWTFWVLLGTMFYWSRIEY
InterPro domains: - IPR008952: Tetraspanin, EC2 domain superfamily (homologous_superfamily) [119-228]
- IPR018499: Tetraspanin/Peripherin (family) [14-250]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0009888 (tissue development), GO:0030154 (cell differentiation), GO:0060429 (epithelium development), GO:0030855 (epithelial cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0005576 (extracellular region), GO:0005615 (extracellular space), GO:0070062 (extracellular exosome), GO:0043227 (membrane-bounded organelle), GO:0043230 (extracellular organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:1903561 (extracellular vesicle)
Protein: Protein HEATR9 (HEAT repeat-containing protein 9) (A2RTY3)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MAYEKSTDISDVSRSMFLYPWLEYPDKTKELRKAMAPVHLPLSCYQMPKEEFPPSPECWRQHPSKPNSVPYCYFKKPEIYTHWHDLYDQREEREAEKMLRKMRDDCRYIKEVHQTHIKMFHLPMSKLTIKSEMRSRPLEPTQDPLKWQRLRELTKSLESPREDEQFYAAQALGCLRISDKFVMEALQQVAQTGPEKVKYEAYRTLAILGCLNKHVIRALIKQLKEKNEGQRMETLTGLRMALNSWAAVSKDKRTQVGDEGKLVPVLQTLIKKSSSEASLEAALCLGFLRPCSNMVQEFLLQCLCQGLKTQRMKALRMLVKVMHVHSAPVIKAILDQLCSSSVLEDRFEATQMLKTIGLEQIQAQGLEELTFNLLRRKTHNEPFLAVRQAVAQTVEELKLKPTMMNLVEAQLMNPDATARQEAVISLGVLGIRSPQVFHLLLDLLDAENHQAVKKSLQETLILCASIDPWIQNKLKNKVLSVYEAPKTNVKAEPTRFQKEPENPEELTIQDFRLAKLNPLFIAKSITKVGQKKTPAFPPCCSKPRKHRPQVIGPWQPRIKKQLRVLAEIAK
InterPro domains: - IPR016024: Armadillo-type fold (homologous_superfamily) [149-476]
- IPR011989: Armadillo-like helical (homologous_superfamily) [134-471]
- IPR052873: HEAT repeat-containing protein 9 (family) [1-490]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0030154 (cell differentiation), GO:0048468 (cell development), GO:0002244 (hematopoietic progenitor cell differentiation), GO:0030097 (hemopoiesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0005930 (axoneme), GO:0005737 (cytoplasm), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0099568 (cytoplasmic region), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0005929 (cilium), GO:0032838 (plasma membrane bounded cell projection cytoplasm), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0097014 (ciliary plasm)
Protein: Fibronectin type-III domain-containing protein (Q3UVK9)
Organism: Mus musculus (Mouse)
Function: Not known
Sequence: MRPLPLWLPSLLLCGLGAAASSPDSFSQLAAPLNPRLHLYNDEQILTWEPSPSSNDPRPVVYQVEYSFIDGSWHRLLEPNCTDITETKCDLTGGGRLKLFPHPFTVFLRVRAKRGNLTSKWVGLEPFQHYENVTVGPPKNISVTPGKGSLVIHFSPPFDVFHGATFQYLVHYWEKSETQQEQVEGPFKSNSIVLGNLKPYRVYCLQTEAQLILKNKKIRSHGLLSNVSCHETTANASARLQQVILIPLGIFALLLGLTGACFTLFLKYQIRVKYWFQAPPNIPEQIEEYLKDPDQFILEVLDKDGSPKEDSWDSVSIISSPEKERDDVLQTP
InterPro domains: - IPR036116: Fibronectin type III superfamily (homologous_superfamily) [30-232]
- IPR003961: Fibronectin type III (domain) [7-236]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [32-238]
- IPR015373: Interferon/interleukin receptor domain (domain) [135-232]
- IPR050650: Type II Cytokine and Tissue Factor Receptors (family) [11-316]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0005488 (binding), GO:0038023 (signaling receptor activity), GO:0005515 (protein binding), GO:0004888 (transmembrane signaling receptor activity), GO:0140375 (immune receptor activity), GO:0004896 (cytokine receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009615 (response to virus), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0140546 (defense response to symbiont), GO:0051607 (defense response to virus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: At3g44100 (MD-2-related lipid recognition domain-containing protein) (Q9LXQ2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MAISQAQPLLLLLLSVFFLPALHATSFTYCDKRLDPVKVTGVKISPDPVVSGAAATFKIFGSTGEDISGGKVVIRVLYVGIPVHTETHDLCDETACPVAPGSFVLSHSQTLPSITPPGTYTLKMTINDKNGGRLTCISFKFKITVGSAVFAS
InterPro domains: - IPR014756: Immunoglobulin E-set (homologous_superfamily) [24-143]
- IPR033917: ML domain, phosphatidylinositol/phosphatidylglycerol transfer protein (domain) [27-141]
- IPR039670: Sterol transport protein NPC2-like (family) [7-144]
- IPR003172: MD-2-related lipid-recognition domain (domain) [25-143]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0006970 (response to osmotic stress), GO:0001101 (response to acid chemical), GO:0010033 (response to organic substance), GO:1901700 (response to oxygen-containing compound), GO:0009414 (response to water deprivation), GO:0010035 (response to inorganic substance), GO:0009415 (response to water), GO:1902074 (response to salt), GO:0009651 (response to salt stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0005773 (vacuole), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000325 (plant-type vacuole), GO:0043231 (intracellular membrane-bounded organelle)
Protein: 60S ribosome subunit biogenesis protein NIP7 homolog (Q389E3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Nucleus, nucleolus {ECO:0000256|ARBA:ARBA00004604}.
Sequence: MRPLTEEETKKLFDKLAQYIGPNTAHLLQQKGTKSAGVAPFNNGKTTGNNGSNDDDDGDDGEEQNSQQTYVFRLHKNRIWYMPLRLAKLASCVAKSNLMGIGVLFAKVTHHGHVRLQVTALEYIAQYSLFKVWLKPSQEQKFLYGGHVTRAGLGRITEATPRHQKVAVFSMGDVPLGFGVAALGTLECRRCEMNSTVLFHEADVGEYLRNEARLT
InterPro domains: - IPR005155: UPF0113, PUA domain (domain) [130-210]
- IPR002478: PUA domain (domain) [130-205]
- IPR055359: 60S ribosome subunit biogenesis protein Nip7, pre-PUA domain, eukaryotes (domain) [2-123]
- IPR040598: 60S ribosome subunit biogenesis protein NIP7, pre-PUA domain (domain) [1-31]
- IPR036974: PUA domain superfamily (homologous_superfamily) [130-215]
- IPR016686: Ribosome biogenesis factor, NIP7 (family) [1-215]
- IPR015947: PUA-like superfamily (homologous_superfamily) [131-205]
Interaction partners: - Nucleolar protein, putative
- Ribosome biogenesis protein, putative
- Ribosome assembly factor mrt4
- Pescadillo homolog
- RNA-binding protein, putative
- rRNA processing protein, putative
- Ribosome biogenesis protein NSA2 homolog
- NLE domain-containing protein
- Nucleolar GTP-binding protein 1
- RNA processing factor 1, putative
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0010467 (gene expression), GO:0042254 (ribosome biogenesis), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0034470 (ncRNA processing), GO:0006364 (rRNA processing), GO:0034660 (ncRNA metabolic process), GO:0016072 (rRNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Matrix protein 2 (Proton channel protein M2) (Q20MH8)
Organism: Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1))
Function: Not known
Subcellular location: Virion membrane {ECO:0000256|HAMAP-Rule:MF_04069}. Host apical cell membrane {ECO:0000256|HAMAP-Rule:MF_04069}; Single-pass type III membrane protein {ECO:0000256|HAMAP-Rule:MF_04069}. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion). {ECO:0000256|HAMAP-Rule:MF_04069}.
Sequence: MSLLTEVETPIRNEWGCRCNDSSDPLVIAANIIGILHLILWILDRLFFKCIYRRFKYGLKRGPSTEGVPESMREEYRKEQQNAVDVDDGHFVNIELE
InterPro domains: - IPR002089: Influenza virus matrix protein 2 (family) [1-97]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0016032 (viral process), GO:0019068 (virion assembly), GO:0019058 (viral life cycle)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0033643 (host cell part), GO:0043657 (host cell), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0030430 (host cell cytoplasm)