Protein: G_PROTEIN_RECEP_F2_4 domain-containing protein (Secretin receptor-like protein SEB-3) (G5EBF7)
Organism: Caenorhabditis elegans
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Sequence: MTSIIRAEYAACQELKKLENSSYNPGGCSVDFDKSLCWASAHIGQQMTRDCPFTFCTAIPGCEEIKDRYMVSRNCNSMGVWQDSNYTMCIKVVEEYAQCLQGFCRVCPDVLRDLVISVSLTLSFVSVILLVAAIVLFSIFDSIQCRRLSIHKNLATAFVFRFAVLAIWTIVQTTNVFQDCTRLTPLPLWDYEWICKAILWFVIYFNVASVMWMLIEGAFLYSRFTVFAMRHSDAPWSLYLACGWGVPFVVVTAWALVHQYISSQQTNSFCWLPYAQGLHLWILAGTMGSALIMNLIFLLMIVVILVQKLRTENSAESKKIWRTIKATLLLVPLLGISNIPLFYEPEHPSSVYMLGSAILQHSQGIFIAVLYCFLNSEIQGALKRQLSKVPFEFFKTRNRFETERTYVPEARNATKNGVPMEEMNKTKNIESGENTESQDQVSTGKQIYSVSTKS
InterPro domains: - IPR001879: GPCR, family 2, extracellular hormone receptor domain (domain) [11-98]
- IPR017983: GPCR, family 2, secretin-like, conserved site (conserved_site) [28-52]
- IPR000832: GPCR, family 2, secretin-like (family) [114-374]
- IPR036445: GPCR family 2, extracellular hormone receptor domain superfamily (homologous_superfamily) [1-100]
- IPR050332: G-protein coupled receptor 2 (family) [6-409]
- IPR017981: GPCR, family 2-like, 7TM (domain) [115-375]
Interaction partners: - Guanine nucleotide-binding protein G
- Neuropeptide-Like Protein
- Guanine nucleotide-binding protein subunit alpha
- Guanine nucleotide-binding protein subunit beta-2
- Guanine nucleotide-binding protein subunit beta-1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0001653 (peptide receptor activity), GO:0008528 (G protein-coupled peptide receptor activity), GO:0004930 (G protein-coupled receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0050793 (regulation of developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0042221 (response to chemical), GO:0051240 (positive regulation of multicellular organismal process), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0051239 (regulation of multicellular organismal process), GO:0071704 (organic substance metabolic process), GO:0003006 (developmental process involved in reproduction), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0044238 (primary metabolic process), GO:0046660 (female sex differentiation), GO:0010171 (body morphogenesis), GO:0048598 (embryonic morphogenesis), GO:1901564 (organonitrogen compound metabolic process), GO:0007186 (G protein-coupled receptor signaling pathway), GO:0048731 (system development), GO:0019538 (protein metabolic process), GO:0048513 (animal organ development), GO:0009790 (embryo development), GO:0048608 (reproductive structure development), GO:0007548 (sex differentiation), GO:0042335 (cuticle development), GO:0046661 (male sex differentiation), GO:0043170 (macromolecule metabolic process), GO:0016477 (cell migration), GO:0006793 (phosphorus metabolic process), GO:0036211 (protein modification process), GO:0061458 (reproductive system development), GO:0043412 (macromolecule modification), GO:0048806 (genitalia development), GO:0048569 (post-embryonic animal organ development), GO:0045138 (nematode male tail tip morphogenesis), GO:0006796 (phosphate-containing compound metabolic process), GO:0007188 (adenylate cyclase-modulating G protein-coupled receptor signaling pathway), GO:0009792 (embryo development ending in birth or egg hatching), GO:0007189 (adenylate cyclase-activating G protein-coupled receptor signaling pathway), GO:0006468 (protein phosphorylation), GO:0016310 (phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)