Protein: HCG2043421, isoform CRA_c (RNA binding protein, mRNA processing factor) (cDNA FLJ61582, highly similar to RNA-binding protein with multiple splicing) (B4E3T4)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MNNGGKAEKENTPSEANLQEEEVRTLFVSGLPLDIKPRELYLLFRPFKGYEGSLIKLTSKQPVGFVSFDSRSEAEAAKNALNGIRFDPEIPQTLRLEFAKANTKMAKNKLVGTPNPSTPLPNTVPQFIAREPYELTVPALYPSSPEVWAPYPLYPAELAPALPPPAFTYPASLHAQVIDTHRPGLHSLHHQSFQTWFPRAHHTTNTYPANRSTLKRLMIPSKSS
InterPro domains: - IPR035979: RNA-binding domain superfamily (homologous_superfamily) [15-109]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [14-111]
- IPR000504: RNA recognition motif domain (domain) [24-101]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0097159 (organic cyclic compound binding), GO:0003712 (transcription coregulator activity), GO:0003676 (nucleic acid binding), GO:0046983 (protein dimerization activity), GO:0042802 (identical protein binding), GO:0003713 (transcription coactivator activity), GO:0042803 (protein homodimerization activity), GO:0003723 (RNA binding), GO:0003727 (single-stranded RNA binding), GO:0070717 (poly-purine tract binding), GO:0008143 (poly(A) binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0023056 (positive regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0019222 (regulation of metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044237 (cellular metabolic process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0009893 (positive regulation of metabolic process), GO:0023051 (regulation of signaling), GO:0006950 (response to stress), GO:0044238 (primary metabolic process), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0006979 (response to oxidative stress), GO:0046483 (heterocycle metabolic process), GO:0009966 (regulation of signal transduction), GO:0060255 (regulation of macromolecule metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0010646 (regulation of cell communication), GO:0031325 (positive regulation of cellular metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0010647 (positive regulation of cell communication), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0010562 (positive regulation of phosphorus metabolic process), GO:0051246 (regulation of protein metabolic process), GO:0090092 (regulation of transmembrane receptor protein serine/threonine kinase signaling pathway), GO:0090304 (nucleic acid metabolic process), GO:0090100 (positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway), GO:0051247 (positive regulation of protein metabolic process), GO:1902533 (positive regulation of intracellular signal transduction), GO:0010467 (gene expression), GO:1902531 (regulation of intracellular signal transduction), GO:0051174 (regulation of phosphorus metabolic process), GO:0016070 (RNA metabolic process), GO:0031399 (regulation of protein modification process), GO:0045937 (positive regulation of phosphate metabolic process), GO:0006396 (RNA processing), GO:0060391 (positive regulation of SMAD protein signal transduction), GO:0019220 (regulation of phosphate metabolic process), GO:0060390 (regulation of SMAD protein signal transduction), GO:0010862 (positive regulation of pathway-restricted SMAD protein phosphorylation), GO:0031401 (positive regulation of protein modification process), GO:0042325 (regulation of phosphorylation), GO:0001932 (regulation of protein phosphorylation), GO:0042327 (positive regulation of phosphorylation), GO:0001934 (positive regulation of protein phosphorylation), GO:0060393 (regulation of pathway-restricted SMAD protein phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0099080 (supramolecular complex), GO:0035770 (ribonucleoprotein granule), GO:0036464 (cytoplasmic ribonucleoprotein granule), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0010494 (cytoplasmic stress granule), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)