Protein: Pentatricopeptide repeat-containing protein GUN1, chloroplastic (Pentatricopeptide repeat-containing protein At2g31400) (Protein GENOMES UNCOUPLED 1) (Q9SIC9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in nuclear gene expression via the retrograde plastid-to-nucleus signaling. Plastid signals that depend on GUN1 can affect photomorphogenesis developments, such as cotyledon opening and expansion, anthocyanin biosynthesis, and hypocotyl elongation.
Subcellular location: Plastid, chloroplast {ECO:0000269|PubMed:17395793}.
Sequence: MASTPPHWVTTTNNHRPWLPQRPRPGRSVTSAPPSSSASVSSAHLSQTTPNFSPLQTPKSDFSGRQSTRFVSPATNNHRQTRQNPNYNHRPYGASSSPRGSAPPPSSVATVAPAQLSQPPNFSPLQTPKSDLSSDFSGRRSTRFVSKMHFGRQKTTMATRHSSAAEDALQNAIDFSGDDEMFHSLMLSFESKLCGSDDCTYIIRELGNRNECDKAVGFYEFAVKRERRKNEQGKLASAMISTLGRYGKVTIAKRIFETAFAGGYGNTVYAFSALISAYGRSGLHEEAISVFNSMKEYGLRPNLVTYNAVIDACGKGGMEFKQVAKFFDEMQRNGVQPDRITFNSLLAVCSRGGLWEAARNLFDEMTNRRIEQDVFSYNTLLDAICKGGQMDLAFEILAQMPVKRIMPNVVSYSTVIDGFAKAGRFDEALNLFGEMRYLGIALDRVSYNTLLSIYTKVGRSEEALDILREMASVGIKKDVVTYNALLGGYGKQGKYDEVKKVFTEMKREHVLPNLLTYSTLIDGYSKGGLYKEAMEIFREFKSAGLRADVVLYSALIDALCKNGLVGSAVSLIDEMTKEGISPNVVTYNSIIDAFGRSATMDRSADYSNGGSLPFSSSALSALTETEGNRVIQLFGQLTTESNNRTTKDCEEGMQELSCILEVFRKMHQLEIKPNVVTFSAILNACSRCNSFEDASMLLEELRLFDNKVYGVVHGLLMGQRENVWLQAQSLFDKVNEMDGSTASAFYNALTDMLWHFGQKRGAELVALEGRSRQVWENVWSDSCLDLHLMSSGAARAMVHAWLLNIRSIVYEGHELPKVLSILTGWGKHSKVVGDGALRRAVEVLLRGMDAPFHLSKCNMGRFTSSGSVVATWLRESATLKLLILHDHITTATATTTTMKSTDQQQRKQTSFALQPLLL
InterPro domains: - IPR036063: Smr domain superfamily (homologous_superfamily) [765-863]
- IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [224-764]
- IPR002885: Pentatricopeptide repeat (repeat) [267-708]
- IPR002625: Smr domain (domain) [781-873]
Interaction partners: - Multiple organellar RNA editing factor 2, chloroplastic
- Magnesium-chelatase subunit ChlH, chloroplastic
- Multiple organellar RNA editing factor 1, mitochondrial
- Tetrapyrrole-binding protein, chloroplastic
- Ethylene-responsive transcription factor ABI4
- Heme oxygenase 1, chloroplastic
- Small ribosomal subunit protein bS1c
- Transcription activator GLK1
- Ferrochelatase-1, chloroplastic/mitochondrial
- Chlorophyll a-b binding protein 3, chloroplastic
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0008380 (RNA splicing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)