Protein: RNA helicase (F1Q5L6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MPGYSDRDRGRDRGSYSSGPPRFGGSRNGPPPAKKFGNPGDRLRKKHWNLDELPKFEKNFYQENPDVARRSAQEVEHYRRSKEITVKGRDGPKPIVKFHEANFPKYVMDVITKQNWTDPTPIQAQGWPVALSGKDMVGIAQTGSGKTLSYLLPAIVHINHQPFLEHGDGPICLVLAPTRELAQQVQQVAAEYGKASRIKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLEAGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKEYIQINVGALQLSANHNILQIVDVCNDGEKEDKLIRLLEEIMSEKENKTIIFVETKRRCDDLTRRMRRDGWPAMGIHGDKNQQERDWVLNEFKYGKAPILIATDVASRGLDVEDVKFVINFDYPNNSEDYIHRIGRTARSQKTGTAYTFFTPNNMKQAHDLVSVLREANQAINPKLIQMAEDRGGRSRGGRGGGYRDDRRDRHSGSRRDFGSYSQDNRSGGDSYGQKKVFGNKTQNGSSSYNNSSSSSSSFNGGGYNNNGQGNFGNQSGGYGNQGYQNQQFPPNQGGVQNGMNHPPPFPFNPQQMPQTMQFPMAPPAFPQ
InterPro domains: - IPR011545: DEAD/DEAH-box helicase domain (domain) [120-290]
- IPR001650: Helicase, C-terminal domain-like (domain) [329-477]
- IPR014014: RNA helicase, DEAD-box type, Q motif (domain) [96-124]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [49-481]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [115-318]
- IPR000629: ATP-dependent RNA helicase DEAD-box, conserved site (conserved_site) [248-256]
Interaction partners: - Regulator of nonsense transcripts 3B
- Pre-mRNA-splicing factor SLU7
- Pre-mRNA-splicing factor CWC22 homolog
- Leukocyte receptor cluster (LRC) member 1
- Pre-mRNA-splicing factor syf2
- Peptidyl-prolyl cis-trans isomerase
- Peptidyl-prolyl cis-trans isomerase
- H/ACA ribonucleoprotein complex subunit DKC1
- Splicing regulator SDE2
- FLJ22626-like
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0008380 (RNA splicing), GO:0006397 (mRNA processing), GO:0016071 (mRNA metabolic process), GO:0000398 (mRNA splicing, via spliceosome), GO:0000375 (RNA splicing, via transesterification reactions), GO:0000377 (RNA splicing, via transesterification reactions with bulged adenosine as nucleophile)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)