wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Anaphase-promoting complex subunit 16 (APC16) (Cyclosome subunit 16) (Q96DE5)
Organism: Homo sapiens (Human)
Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:20360068}. Nucleus {ECO:0000269|PubMed:20360068}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:20813266}.
Sequence: MAASSSSSSAGGVSGSSVTGSGFSVSDLAPPRKALFTYPKGAGEMLEDGSERFLCESVFSYQVASTLKQVKHDQQVARMEKLAGLVEELEADEWRFKPIEQLLGFTPSSG
InterPro domains: - IPR029641: Anaphase-promoting complex subunit 16 (family) [1-110]
Interaction partners: - Anaphase-promoting complex subunit 10
- Anaphase-promoting complex subunit CDC26
- Anaphase-promoting complex subunit 7
- Anaphase-promoting complex subunit 1
- Cell division cycle protein 23 homolog
- Cell division cycle protein 27 homolog
- Anaphase-promoting complex subunit 5
- Cell division cycle protein 20 homolog
- Cell division cycle protein 16 homolog
- Anaphase-promoting complex subunit 15
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0044248 (cellular catabolic process), GO:0009057 (macromolecule catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0006508 (proteolysis), GO:0044265 (cellular macromolecule catabolic process), GO:0030163 (protein catabolic process), GO:0043632 (modification-dependent macromolecule catabolic process), GO:0010498 (proteasomal protein catabolic process), GO:0051603 (proteolysis involved in protein catabolic process), GO:0019941 (modification-dependent protein catabolic process), GO:0043161 (proteasome-mediated ubiquitin-dependent protein catabolic process), GO:0006511 (ubiquitin-dependent protein catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: J domain-containing protein (Q9TY07)
Organism: Caenorhabditis elegans
Function: Not known
Sequence: MAPREDSPYITLGISSTSDDVEIKKAYRKLALKWHPDKHTDDKSKEEAEQKFKKIAQAYEILTDKKKRADLDRTENPGLHRRRSTPGGMHRMHSHDMFRSPFDIFREFFGNRDPFENVFFDDAFTFPDVDSYAFKHPPRSADFTTKNHYHRFPSSRVHIFYDENKNTKERDDKNTFSTVIRFSSPTEPGKNATVRKTSTSTKLVDGKKIVTKTVENGDEHIVEVHEDGELKCRTVTTPPTSPTVTVAAI
InterPro domains: - IPR001623: DnaJ domain (domain) [6-75]
- IPR043183: DnaJ homolog subfamily B member 2/6-like (family) [9-237]
- IPR036869: Chaperone J-domain superfamily (homologous_superfamily) [4-120]
Interaction partners: - Heat shock protein hsp-1
- Heat shock protein 110
- Heat shock protein 70
- Heat shock 70 kDa protein C
- DUF148 domain-containing protein
- Heat shock protein hsp-6
- Heat-shock protein 12.1
- BAG domain-containing protein
- Activator of Hsp90 ATPase AHSA1-like N-terminal domain-containing protein
- Heat shock protein 70
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0031072 (heat shock protein binding), GO:0030544 (Hsp70 protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0006950 (response to stress), GO:0009628 (response to abiotic stimulus), GO:0009408 (response to heat), GO:0009266 (response to temperature stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Immunogenic protein MPT70 (P9WNF5)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Not known
Subcellular location: Secreted.
Sequence: MKVKNTIAATSFAAAGLAALAVAVSPPAAAGDLVGPGCAEYAAANPTGPASVQGMSQDPVAVAASNNPELTTLTAALSGQLNPQVNLVDTLNSGQYTVFAPTNAAFSKLPASTIDELKTNSSLLTSILTYHVVAGQTSPANVVGTRQTLQGASVTVTGQGNSLKVGNADVVCGGVSTANATVYMIDSVLMPPA
InterPro domains: - IPR000782: FAS1 domain (domain) [57-192]
- IPR036378: FAS1 domain superfamily (homologous_superfamily) [31-193]
- IPR050904: Cell adhesion and biosynthesis-related protein (family) [63-193]
Interaction partners: - Protein DipZ
- ECF RNA polymerase sigma factor SigK
- NADH-quinone oxidoreductase subunit D
- Immunogenic protein MPT64
- Anti-sigma-K factor RskA
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0030246 (carbohydrate binding), GO:0030247 (polysaccharide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006091 (generation of precursor metabolites and energy), GO:0015980 (energy derivation by oxidation of organic compounds), GO:0045333 (cellular respiration), GO:0009060 (aerobic respiration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005576 (extracellular region), GO:0005618 (cell wall), GO:0009274 (peptidoglycan-based cell wall)
Protein: Cilia- and flagella-associated protein 91 (Flagellar-associated protein 91) (Q386N1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Axoneme-associated protein involved in flagellum motility and central pair positioning.
Subcellular location: Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:32161152}.
Sequence: MYYRTQQKPASVLGANGFTAEVGGRDRVRYFRPPVEVAGVPMRYSGIDTVRFSATAPTTPNLPRTFAETRFDRPTSMAAGLVGPPHHLPSLPRRAGAAPPHPVKAKSVKLPPQRTKRVEKLASTIGTDGKCDAAMQTVFRENEAQTLPYTPNYYIPEGGDPNPQVLGLMELHWNEGLPAGKEEVELIQRLRRRRAVEASLLDETSKEAKMENFCKLYDLEVKEREEREQHFENLRKRRLDQIHEALQERERARDELNRQRLEKVKEQRLANLQRVIEQMESKRVGMGRKALAEQASKAPAAAGRGLYAVDPIETFKRKPDLIQTYARRGTGAVEPQLCTNNGGGSASASPRRDRSRKPLRNYRQYDIQPAMLKYEGGIAELEANKIPKIQQIAPNAFAAPENHAINSLPSLYQRREATRVVEALEYVHAKIHKSDTPAETIRVLELYRATPRPQRPDTPTLELEGDVNEAVEESCTLLQRLLRGRAVQNDFFDGKERCRGLIEELQAASNAKYAERSAEEKQAEAEEKMREAIADSIGNEAQGDIICDTLDYLFHEMTRQQDLLALEALRHEAEAVRAEREAREAELRAQERILHDKEAVQYAAYVRAIEDIVECYSHDLYATVAEECAMEEAIEAECQRLEQLPPPTSNILSDPEVAENLVCDVLDNFVLPAVIDMVRMKPEELDRKAPAAAAAGFRQRSPNEKETKE
InterPro domains: - IPR026720: Cilia- and flagella-associated protein 91 (family) [19-708]
- IPR032840: CFAP91 domain (domain) [135-289]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0007017 (microtubule-based process), GO:0016043 (cellular component organization), GO:0000226 (microtubule cytoskeleton organization), GO:0044085 (cellular component biogenesis), GO:0030030 (cell projection organization), GO:0006996 (organelle organization), GO:0001578 (microtubule bundle formation), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0007010 (cytoskeleton organization), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0044782 (cilium organization), GO:0035082 (axoneme assembly), GO:0060271 (cilium assembly), GO:0120031 (plasma membrane bounded cell projection assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0005930 (axoneme), GO:0005737 (cytoplasm), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0099568 (cytoplasmic region), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0005929 (cilium), GO:0032838 (plasma membrane bounded cell projection cytoplasm), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0097014 (ciliary plasm)
Protein: Epididymal-specific lipocalin-9 (MUP-like lipocalin) (Q8WX39)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Secreted.
Sequence: MALLLLSLGLSLIAAQEFDPHTVMQRNYNVARVSGVWYSIFMASDDLNRIKENGDLRVFVRNIEHLKNGSLIFDFEYMVQGECVAVVVVCEKTEKNGEYSINYEGQNTVAVSETDYRLFITFHLQNFRNGTETHTLALYETCEKYGLGSQNIIDLTNKDPCYSKHYRSPPRPPMRW
InterPro domains: - IPR012674: Calycin (homologous_superfamily) [22-168]
- IPR000566: Lipocalin/cytosolic fatty-acid binding domain (domain) [34-155]
- IPR022272: Lipocalin family conserved site (conserved_site) [27-40]
- IPR002345: Lipocalin (family) [4-140]
- IPR002971: Major urinary protein (family) [34-126]
Interaction partners: - Epididymal-specific lipocalin-8
- Cystatin-11
- Epididymal-specific lipocalin-6
- Epididymal-specific lipocalin-12
- Epididymal-specific lipocalin-10
- Lipocalin-1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0007610 (behavior), GO:0007635 (chemosensory behavior)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Putative metacaspase (E9AEY0)
Organism: Leishmania major
Function: Not known
Sequence: MADLFDIWGIGAVASLIPMLANGLLLVDRPKRVDINAGRRLIHTVRPIIPYRAPVPYTGGRVRALFIGINYTGMRNALRGCVNDVSSMLGTLQQISFPISECCILVDDPSFPGFCGMPTRDNIIKHMLWLTGDVRPGDVLFFHFSGHGGQAKATRDSEEKYDQCLIPLDHVKNGSILDDDLFLMLVAPLPSGVRMTCVFDCCHSASMLDLPFSYVAPRVGGGGACEYMQQVRRGNFSNGDVVMFSGCTDRGTSADVQNGGHANGAATLAFTWSLLNTHGLSYLNILLKTREELRKKGRVQVPQLTSSKPIDLYKPFSLFGMITVNASMMHCVPQQYQQRPQSLPPQVMPPATGYPVHVPPPPQGYYPPPQSPGWGLGYPVQGIPVQQATLGVSRCPPSQYLPAPPPAVYAPPPPGQRGPPQPPPAQYTFSPLPPG
InterPro domains: - IPR050452: Metacaspase (family) [59-317]
- IPR011600: Peptidase C14, caspase domain (domain) [63-308]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008234 (cysteine-type peptidase activity), GO:0004175 (endopeptidase activity), GO:0004197 (cysteine-type endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0006508 (proteolysis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle)
Protein: Allophycocyanin alpha chain (Q01951)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex. Allophycocyanin has a maximum absorption at approximately 650 nanometers.
Subcellular location: Cellular thylakoid membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Forms the core of the phycobilisome. {ECO:0000250}.
Sequence: MSIVTKSIVNADAEARYLSPGELDRIKAFVTGGAARLRIAETLTGSRETIVKQAGDRLFQKRPDIVSPGGNAYGEEMTATCLRDMDYYLRLVTYGVVSGDVTPIEEIGLVGVREMYRSLGTPIEAVAQSVREMKEVASGLMSSDDAAEASAYFDFVIGKMS
InterPro domains: - IPR038719: Phycobilisome, alpha/beta subunit superfamily (homologous_superfamily) [1-160]
- IPR009050: Globin-like superfamily (homologous_superfamily) [2-161]
- IPR012128: Phycobilisome, alpha/beta subunit (family) [1-161]
Interaction partners: - C-phycocyanin alpha subunit
- Phycobilisome 7.8 kDa linker polypeptide, allophycocyanin-associated, core
- Phycobilisome rod-core linker polypeptide CpcG
- C-phycocyanin beta subunit
- Allophycocyanin beta chain
- Phycobilisome 32.1 kDa linker polypeptide, phycocyanin-associated, rod 1
- Phycobiliprotein ApcE
- Phycobilisome 32.1 kDa linker polypeptide, phycocyanin-associated, rod 2
- Allophycocyanin subunit beta-18
- Photosystem I-associated linker protein CpcL
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044281 (small molecule metabolic process), GO:0044237 (cellular metabolic process), GO:0006730 (one-carbon metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:0043229 (intracellular organelle), GO:0034357 (photosynthetic membrane), GO:0043228 (non-membrane-bounded organelle), GO:0042651 (thylakoid membrane), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0009579 (thylakoid)
Protein: 3-methylornithine synthase (EC 5.4.99.58) ((2R,3R)-3-methylornithine synthase) ((3R)-3-methyl-D-ornithine synthase) (Pyrrolysine biosynthesis protein PylB) (Q46E78)
Organism: Methanosarcina barkeri (strain Fusaro / DSM 804)
Function: Catalyzes the isomerization of L-lysine to (2R,3R)-3-methylornithine via a radical-based mechanism, a step in the biosynthesis pathway of pyrrolysine.
Sequence: MIQKMALDEFDSLGDKVIEGYQLTDNDLRTLLSLESKEGLERLYSAARKVRDHYFGNRVFLNCFIYFSTYCKNQCSFCYYNCRNEINRYRLTMEEIKETCKTLKGAGFHMVDLTMGEDPYYYEDPNRFVELVQIVKEELGLPIMISPGLMDNATLLKAREKGANFLALYQETYDTELYRKLRVGQSFDGRVNARRFAKQQGYCVEDGILTGVGNDIESTILSLRGMSTNDPDMVRVMTFLPQEGTPLEGFRDKSNLSELKIISVLRLMFPKRLIPASLDLEGIDGMVLRLNAGANIVTSILPPDSQLEGVANYDRDLEERDRDIKSVVRRLEIMGMKPARQADFEAVLGC
InterPro domains: - IPR007197: Radical SAM (domain) [57-279]
- IPR006638: Elp3/MiaA/NifB-like, radical SAM core domain (domain) [61-270]
- IPR013785: Aldolase-type TIM barrel (homologous_superfamily) [1-350]
- IPR023891: Pyrrolysine biosynthesis protein PylB (family) [4-349]
- IPR034422: HydE/PylB-like (family) [11-340]
Interaction partners: - 3-methyl-D-ornithine--L-lysine ligase
- Pyrrolysine--tRNA ligase
- Diaminopimelate decarboxylase
- Pyrrolysine synthase
- Monomethylamine methyltransferase MtmB1
- L-lysine 2,3-aminomutase
- Biotin synthesis BioY protein
- Biotin--
- Methylcobamide:CoM methyltransferase MtaA
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006575 (cellular modified amino acid metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0043603 (amide metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0046483 (heterocycle metabolic process), GO:0006082 (organic acid metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0043604 (amide biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0042398 (cellular modified amino acid biosynthetic process), GO:0016053 (organic acid biosynthetic process), GO:0043436 (oxoacid metabolic process), GO:0018130 (heterocycle biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Gpt1p (A0A1D8PDH1)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MNSGIHTPHEIHPVVSQVHVDDMGIASILSNKNITINVDHVIDSDEAMLLAIGYRQELRREFSLWSIFAVSFSVLGLLPSIAACFDYQQLVVGMSPLPWLIAMIFITSVAYSMAEIASAFPCSAGTPYAVSQLAPKKYASFLTWFTCWTNWSCQITAAPSVSYSCACMMLALHSFTDPSFVASNAQIFGLTTGIQVLCAFMACFPTKWVARFSSAGTTCNIVFLVVVFVMILGGNKRDQIKEGISKFNSNSTAWGLDNQAEWPTGLSFLISFMGVIWAMSGYDSPFHLAEECSNAAVAAPRAIVLTSTVGGLIGFMFMIAIAYTLVDLNQISADPEGLGQPFVTYLTQIMDKNLVIGATALTIISSFFMAQNCLLASSRVTYAYARDGLFPLSGIWKKVSPKTQTPINAVIMNFIVEELLLLLIFGGDVSIGSIFSIGALAGFISFTMPTLLKITYARKTFQPGPWNLGKWSEPIGWVSVAFVGLMVPILCFPTVKGADLTPTEMNWTCLVYFGLILLTTIWFVVDARRWYVGPRTNISEEDIVYGEKTEDEGDEIPDVIDGQKVSISSTEKRYQ
InterPro domains: - IPR002293: Amino acid/polyamine transporter I (family) [62-514]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0005342 (organic acid transmembrane transporter activity), GO:1901474 (azole transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity), GO:0015189 (L-lysine transmembrane transporter activity), GO:0046943 (carboxylic acid transmembrane transporter activity), GO:0015171 (amino acid transmembrane transporter activity), GO:0015173 (aromatic amino acid transmembrane transporter activity), GO:0015174 (basic amino acid transmembrane transporter activity), GO:0015179 (L-amino acid transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0006810 (transport), GO:1903825 (organic acid transmembrane transport), GO:1905039 (carboxylic acid transmembrane transport), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:0006865 (amino acid transport), GO:0015849 (organic acid transport), GO:0015711 (organic anion transport), GO:0003333 (amino acid transmembrane transport), GO:0046942 (carboxylic acid transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: LD31195p (Sprouty-related protein with EVH-1 domain, isoform B) (F0JAK5)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MTEGHESDFLVTVRAQVMTRDESTEGWLPLAGGGLANVSIRKRARLSPLASGHDYIIYGQRISDQSVILSCVINRDLKYYKVMPTFHHWRAGKQRNGLTFQTAADARAFDKGVLRAYNELIDDDVFMTLDLPVESESLQKIHSSPEGSEKSHKSVSNNSDSEKLPPPPIHYISTDKTSATTSPPDAPPASAAPSPATAGQIAASENYSYVTLTAVHHDYNYPVVDQPVGAQVLNARRESISALKKRNALEAAQAMAAAQTAAGGGLACRDGGSGKPLHKPNVSDILKKETRLRCRYCHELYSEDFNRRGACEYAPDAFRSGYECISGMGCARCMIYHCMSDAEGETAQHPCDCSASEAGCSKRWLGLAILSLFVPCLWCYPPLRACHLAGIHCGLCGGQHKPHV
InterPro domains: - IPR000697: WH1/EVH1 domain (domain) [1-120]
- IPR041937: SPRE, EVH1 domain (domain) [9-122]
- IPR007875: Sprouty (family) [291-402]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [1-125]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0048519 (negative regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0023057 (negative regulation of signaling), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0007389 (pattern specification process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0090287 (regulation of cellular response to growth factor stimulus), GO:0035295 (tube development), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0009887 (animal organ morphogenesis), GO:0003002 (regionalization), GO:0010646 (regulation of cell communication), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009966 (regulation of signal transduction), GO:0090288 (negative regulation of cellular response to growth factor stimulus), GO:0035239 (tube morphogenesis), GO:0045746 (negative regulation of Notch signaling pathway), GO:0048514 (blood vessel morphogenesis), GO:0090101 (negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0090596 (sensory organ morphogenesis), GO:0090092 (regulation of transmembrane receptor protein serine/threonine kinase signaling pathway), GO:0030510 (regulation of BMP signaling pathway), GO:0048592 (eye morphogenesis), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0001745 (compound eye morphogenesis), GO:0048749 (compound eye development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)