Protein: Boron transporter 1 (Q8VYR7)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Efflux-type boron (B) transporter for xylem loading, responsive of boron translocation from roots to shoots under boron limitation. Boron is essential for maintaining the integrity of plants cell walls.
Subcellular location: Cell membrane {ECO:0000269|PubMed:12447444, ECO:0000269|PubMed:27449211}; Multi-pass membrane protein {ECO:0000255}. Endosome membrane {ECO:0000269|PubMed:12447444, ECO:0000269|PubMed:16103374, ECO:0000269|PubMed:27449211}; Multi-pass membrane protein {ECO:0000255}. Vacuole membrane {ECO:0000269|PubMed:12447444, ECO:0000269|PubMed:16103374, ECO:0000269|PubMed:27449211}; Multi-pass membrane protein {ECO:0000255}. Note=Transferred from the plasma membrane via the endosomes to the vacuole under high-concentration of boron in a DRP1A-dependent manner (PubMed:16103374, PubMed:20194745, PubMed:27449211). Localized to the polar inner/stele-side domain of the plasma membrane under low-boron conditions, this polar localization is established after cell division (PubMed:27449211). Co-localizes with DRP1A in the cell plate and the plasma membrane (PubMed:27449211). Under boron excess, BOR1 is transferred from the plasma membrane via the endosomes to the vacuole for degradation in a DRP1A-dependent manner (PubMed:16103374, PubMed:20194745, PubMed:27449211). {ECO:0000269|PubMed:16103374, ECO:0000269|PubMed:20194745, ECO:0000269|PubMed:27449211}.
Sequence: MEETFVPFEGIKNDLKGRLMCYKQDWTGGFKAGFRILAPTTYIFFASAIPVISFGEQLERSTDGVLTAVQTLASTAICGMIHSIIGGQPLLILGVAEPTVIMYTFMFNFAKARPELGRDLFLAWSGWVCVWTALMLFVLAICGACSIINRFTRVAGELFGLLIAMLFMQQAIKGLVDEFRIPERENQKLKEFLPSWRFANGMFALVLSFGLLLTGLRSRKARSWRYGTGWLRSLIADYGVPLMVLVWTGVSYIPAGDVPKGIPRRLFSPNPWSPGAYGNWTVVKEMLDVPIVYIIGAFIPASMIAVLYYFDHSVASQLAQQKEFNLRKPSSYHYDLLLLGFLTLMCGLLGVPPSNGVIPQSPMHTKSLATLKYQLLRNRLVATARRSIKTNASLGQLYDNMQEAYHHMQTPLVYQQPQGLKELKESTIQATTFTGNLNAPVDETLFDIEKEIDDLLPVEVKEQRVSNLLQSTMVGGCVAAMPILKMIPTSVLWGYFAFMAIESLPGNQFWERILLLFTAPSRRFKVLEDYHATFVETVPFKTIAMFTLFQTTYLLICFGLTWIPIAGVMFPLMIMFLIPVRQYLLPRFFKGAHLQDLDAAEYEEAPALPFNLAAETEIGSTTSYPGDLEILDEVMTRSRGEFRHTSSPKVTSSSSTPVNNRSLSQVFSPRVSGIRLGQMSPRVVGNSPKPASCGRSPLNQSSSN
InterPro domains: - IPR003020: Bicarbonate transporter, eukaryotic (family) [2-606]
- IPR011531: Bicarbonate transporter-like, transmembrane domain (domain) [7-600]
Interaction partners: - Probable aquaporin NIP5-1
- peptidylprolyl isomerase
- Aquaporin NIP6-1
- Receptor-like cytosolic serine/threonine-protein kinase RBK2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0015562 (efflux transmembrane transporter activity), GO:0015103 (inorganic anion transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0015698 (inorganic anion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016328 (lateral plasma membrane), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0012505 (endomembrane system), GO:0030312 (external encapsulating structure), GO:0005773 (vacuole), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)