Protein: Prb1p (Q59Z57)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Sequence: MKVTNVISFATVASTAVSLVIPDITSFFSSFNQILIPHHQQALLINQDAHLPSDDNQPDTKTGILSNPLNKIIPNHYIVVLKDDLSQAQFLQHQNWVQNEHVSISSCKSNVNKKPLEFFQIDNFVRGYTGFFTDDLINKILELPEVAFVERDSIFHTVEFDIQKDATWGISRVSHRENIDDGKYLFDNDGGKGVTAYVIDTGIKVGHPDFEDRAQWGASIAFPNIKQDYNGHGTHCAGTIGSKTYGIAKNVNLVAVGVMNMLGAGSTSDIIKGLEFVVKSHQDDVRAKKKGFKGSTVNMSIGGGISDALDLAVNAGTKAGLHISVAAGNDNADACQYSPARATGPITIGASNIRDEKASFSNWGSCVDLFAPGEDIESTFIWSDTTVMSGTSMASPHIAGLLSYYLSLQPDVTSEFYTQAIEPADLKNKLIKYGTKGVLTGLDSVSPNILAFNGAGGNLTDFWSL
InterPro domains: - IPR023827: Peptidase S8, subtilisin, Asp-active site (active_site) [196-207]
- IPR000209: Peptidase S8/S53 domain (domain) [191-420]
- IPR022398: Peptidase S8, subtilisin, His-active site (active_site) [232-242]
- IPR050131: Subtilisin-like serine protease (family) [40-435]
- IPR010259: Peptidase S8 propeptide/proteinase inhibitor I9 (domain) [77-157]
- IPR036852: Peptidase S8/S53 domain superfamily (homologous_superfamily) [70-458]
- IPR023828: Peptidase S8, subtilisin, Ser-active site (active_site) [390-400]
- IPR037045: Peptidase S8 propeptide/proteinase inhibitor I9 superfamily (homologous_superfamily) [75-157]
- IPR015500: Peptidase S8, subtilisin-related (family) [191-405]
- IPR034193: Proteinase K-like catalytic domain (domain) [168-436]
Interaction partners: - Proteinase B
- Autophagy-related protein 8
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0017171 (serine hydrolase activity), GO:0008233 (peptidase activity), GO:0008236 (serine-type peptidase activity), GO:0004175 (endopeptidase activity), GO:0004252 (serine-type endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0048856 (anatomical structure development), GO:0009653 (anatomical structure morphogenesis), GO:0044237 (cellular metabolic process), GO:0009607 (response to biotic stimulus), GO:0006807 (nitrogen compound metabolic process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0061919 (process utilizing autophagic mechanism), GO:0071704 (organic substance metabolic process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0009056 (catabolic process), GO:0051707 (response to other organism), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0043207 (response to external biotic stimulus), GO:0042594 (response to starvation), GO:0033554 (cellular response to stress), GO:0044248 (cellular catabolic process), GO:0019538 (protein metabolic process), GO:0030435 (sporulation resulting in formation of a cellular spore), GO:1901575 (organic substance catabolic process), GO:0043170 (macromolecule metabolic process), GO:0006914 (autophagy), GO:0030242 (autophagy of peroxisome), GO:0016236 (macroautophagy), GO:0009057 (macromolecule catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0009267 (cellular response to starvation), GO:0031667 (response to nutrient levels), GO:0030163 (protein catabolic process), GO:0031669 (cellular response to nutrient levels), GO:0061912 (selective autophagy), GO:0007039 (protein catabolic process in the vacuole)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0005576 (extracellular region), GO:0043227 (membrane-bounded organelle), GO:0043230 (extracellular organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:1903561 (extracellular vesicle)