Protein: Small conductance calcium activated potassium channel type 4 transcript variant 2 (D1MQ08)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MHDQHFHLLTPLPHRGLSCQRGPAVHDRQRAAGLARGADRAAGNASYRSIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIQYTKEMKESAARVLQEAWMFYKHTRRKESHAARRHQRKLLAAINAFRQVRLKHRKLREQVNSMVDISKMHMILYDLQQNLSSSHRALEKQIDTLAGKLDALTELLSTALGPRQLPEPSQQSK
InterPro domains: - IPR013099: Potassium channel domain (domain) [80-157]
- IPR015449: Potassium channel, calcium-activated, SK (family) [43-282]
- IPR036122: SK, calmodulin-binding domain superfamily (homologous_superfamily) [155-243]
- IPR004178: Calmodulin-binding domain (domain) [172-245]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0005515 (protein binding), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0019899 (enzyme binding), GO:0015079 (potassium ion transmembrane transporter activity), GO:0015267 (channel activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0019902 (phosphatase binding), GO:0005216 (monoatomic ion channel activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0046873 (metal ion transmembrane transporter activity), GO:0005261 (monoatomic cation channel activity), GO:0022839 (monoatomic ion gated channel activity), GO:0005267 (potassium channel activity), GO:0022836 (gated channel activity), GO:0019903 (protein phosphatase binding), GO:0005227 (calcium activated cation channel activity), GO:0015269 (calcium-activated potassium channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0065008 (regulation of biological quality), GO:0023056 (positive regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0032879 (regulation of localization), GO:0002684 (positive regulation of immune system process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051234 (establishment of localization), GO:0002682 (regulation of immune system process), GO:0023051 (regulation of signaling), GO:0006950 (response to stress), GO:0051050 (positive regulation of transport), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0051049 (regulation of transport), GO:0050776 (regulation of immune response), GO:0010646 (regulation of cell communication), GO:0043270 (positive regulation of monoatomic ion transport), GO:0042391 (regulation of membrane potential), GO:0006810 (transport), GO:0009966 (regulation of signal transduction), GO:0006952 (defense response), GO:0034762 (regulation of transmembrane transport), GO:0050778 (positive regulation of immune response), GO:0034764 (positive regulation of transmembrane transport), GO:0010647 (positive regulation of cell communication), GO:0034767 (positive regulation of monoatomic ion transmembrane transport), GO:0043268 (positive regulation of potassium ion transport), GO:0034765 (regulation of monoatomic ion transmembrane transport), GO:0050857 (positive regulation of antigen receptor-mediated signaling pathway), GO:0050854 (regulation of antigen receptor-mediated signaling pathway), GO:0071702 (organic substance transport), GO:0043269 (regulation of monoatomic ion transport), GO:0006811 (monoatomic ion transport), GO:0006812 (monoatomic cation transport), GO:1904062 (regulation of monoatomic cation transmembrane transport), GO:1904064 (positive regulation of cation transmembrane transport), GO:1901381 (positive regulation of potassium ion transmembrane transport), GO:0050856 (regulation of T cell receptor signaling pathway), GO:0006816 (calcium ion transport), GO:0010959 (regulation of metal ion transport), GO:0043266 (regulation of potassium ion transport), GO:0030001 (metal ion transport), GO:1901379 (regulation of potassium ion transmembrane transport), GO:0006813 (potassium ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)