Protein: Factor arrest protein 11 (P53917)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Participates in the control of the reentry into the cell cycle following pheromone treatment.
Sequence: MNASGRSHSKGPIIRSVSLEDLKRNSSFKGNLKYKDEVTSHKEPQVGTLSNEELLKDLDNMLRGKLNMGRNSFHADKRNKSDGNISALTFKARSGLEGDIRTIDIQQDSSDENDNFKFSDDGVNKDRNNEKDNNTDNAVEFQDDAEEAEEENEDESFANVDELDGFDLNKVSDGKHVPINEKGEVDYNMPVDKEFQKSLDQCAASLEERSSAPYALQRAVDWELKMFYSLEDELSEWFCSSDYMHFGQTQTLFKQKITQPQLFFDDENYAASVVECLIEDIPNSLASNLLALSYISMGCFAFTNSKSEHTKIIRRNNLMLVPHIQEIVHAFKKIAISCRDDNRNLKKQTILLFHSSTILYFICSICIEGRGENPEAVNVVIDAFEKTDLLEFLTKYIENWRWNSRLAMRIRNMISLLFKLIVLQFGDSSVYKQTKSSIYNLHGLTYPSKHPEKLSISPLHYQAFREDITSRFPDYNMPSSGLPKDVDKSESLSQFLEIPRPKSKNPLNMALIVPEKHIATPAPSPPSSPQLMHLGEGPRPRKSFQTNMAYPCLYPSDNEGSEDDTLEDRIDLNIERKPDNDIVIPFSTEEAARILSESLEIKLSTKQLWYERDLFMITERGWKQQLENEPYDYAALNHDANSSKEEKSAICIMQRIDKYYKSCLSSFNSLVFVLLQTMESSLTNNFHRKSEVSDKNLLNMLTPQLEIVRAKELSLKSAAGILHALLKWFKLSHILKFEHLAVVIHDSRYINTCASILSKYSEVYPERVFNKYVQTPNSFWKECSLSNESYRESYSVDDSGEVDTEIMPSFAYLLRILRKVTGNKTQRLKELPLSIGILFKRYYRLFNLDMYHPILKITRELTPFKNKRWKSEHMELISGVYLYEKLELTDNWVTGKDISGELSDACGQEIALRALLQFYNFQHYEISMEDLGYGHRNSSSQDLLNKESEYLNI
InterPro domains: - IPR012486: Far11/STRP, N-terminal (domain) [217-488]
- IPR040185: Far11/STRP (family) [1-949]
- IPR021819: Far11/STRP, C-terminal (domain) [585-950]
Interaction partners: - Factor arrest protein 8
- Factor arrest protein 3
- Vacuolar protein sorting-associated protein 64
- Factor arrest protein 10
- Protein phosphatase PP2A regulatory subunit A
- Factor arrest protein 7
- Serine/threonine-protein phosphatase PP2A-1 catalytic subunit
- Serine/threonine-protein phosphatase PP2A-like PPG1
- Serine/threonine-protein phosphatase PP2A-2 catalytic subunit
- Serine/threonine-protein kinase KIC1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0048519 (negative regulation of biological process), GO:0051641 (cellular localization), GO:0031503 (protein-containing complex localization), GO:0050794 (regulation of cellular process), GO:0051234 (establishment of localization), GO:0051716 (cellular response to stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0007017 (microtubule-based process), GO:0048523 (negative regulation of cellular process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0033036 (macromolecule localization), GO:0044085 (cellular component biogenesis), GO:0051129 (negative regulation of cellular component organization), GO:0046907 (intracellular transport), GO:0035556 (intracellular signal transduction), GO:0006810 (transport), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0016043 (cellular component organization), GO:0000226 (microtubule cytoskeleton organization), GO:0051128 (regulation of cellular component organization), GO:0045184 (establishment of protein localization), GO:0044087 (regulation of cellular component biogenesis), GO:0010970 (transport along microtubule), GO:0006886 (intracellular protein transport), GO:0030030 (cell projection organization), GO:0071705 (nitrogen compound transport), GO:0031344 (regulation of cell projection organization), GO:0015031 (protein transport), GO:0030705 (cytoskeleton-dependent intracellular transport), GO:0072594 (establishment of protein localization to organelle), GO:0071702 (organic substance transport), GO:0033043 (regulation of organelle organization), GO:0008104 (protein localization), GO:0007264 (small GTPase mediated signal transduction), GO:0007034 (vacuolar transport), GO:0006996 (organelle organization), GO:1902115 (regulation of organelle assembly), GO:0099111 (microtubule-based transport), GO:0060491 (regulation of cell projection assembly), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0007010 (cytoskeleton organization), GO:0033365 (protein localization to organelle), GO:0120032 (regulation of plasma membrane bounded cell projection assembly), GO:1902116 (negative regulation of organelle assembly), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0045724 (positive regulation of cilium assembly), GO:0072659 (protein localization to plasma membrane), GO:0030031 (cell projection assembly), GO:1902017 (regulation of cilium assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0044782 (cilium organization), GO:0035082 (axoneme assembly), GO:0120031 (plasma membrane bounded cell projection assembly), GO:0060271 (cilium assembly), GO:0072665 (protein localization to vacuole)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005773 (vacuole), GO:0005816 (spindle pole body), GO:0031967 (organelle envelope), GO:0005635 (nuclear envelope), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0000322 (storage vacuole), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0000324 (fungal-type vacuole), GO:0005634 (nucleus), GO:0015630 (microtubule cytoskeleton)