Protein: ATP synthase subunit alpha (A0A1D8PDC4)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Sequence: MLSARPVLRTAARTATIAARSSLRVARPTLLTAQRFASAKAAPTEVSSILEDRIRGVSEEANLNETGRVLSVGDGIARIYGLNNIQAEELVEFSSGAKGMALNLEADQVGVVLFGSDRLVKEGETVKRTGQIVSVPIGPELLGRVVDGLGNPIDGKGPIKAAAYSRAQVKAPGILPRRSVHEPMQTGLKSVDALVPIGRGQRELIIGDRQTGKTAVALDAILNQKRWNNGSDEKKKLYCVYVAVGQKRSTVAQLVQTLEQHDALKYSVIVAATASEAAPLQYIAPFTACAIGEWFRDNGRHALIVYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKMSDAYGGGSLTALPVIETQGGDVSAYIPTNVISITDGQIFLEAELFYKGIRPAINVGLSVSRVGSAAQVKAMKQVAGSLKLFLAQYREVAAFAQFGSDLDASTKQTLNRGERLTQLLKQKQYNPLAAEEQVPLIFAGVNGFLDNVALDRIGEFEEAFLGHLKSNETGILDAIKTKGELSKDELEKLRKVTEEFVASF
InterPro domains: - IPR023366: ATP synthase subunit alpha, N-terminal domain-like superfamily (homologous_superfamily) [37-131]
- IPR033732: ATP synthase, F1 complex, alpha subunit nucleotide-binding domain (domain) [132-413]
- IPR000793: ATP synthase, alpha subunit, C-terminal (domain) [417-546]
- IPR005294: ATP synthase, F1 complex, alpha subunit (family) [39-546]
- IPR020003: ATPase, alpha/beta subunit, nucleotide-binding domain, active site (active_site) [401-410]
- IPR004100: ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (domain) [65-130]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [132-417]
- IPR000194: ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (domain) [187-410]
- IPR036121: ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily (homologous_superfamily) [48-132]
- IPR038376: ATP synthase, alpha subunit, C-terminal domain superfamily (homologous_superfamily) [418-546]
Interaction partners: - Uncharacterized protein
- ATP synthase subunit a
- ATP synthase subunit beta
- ATP synthase subunit 9, mitochondrial
- ATP synthase subunit 5
- ATP synthase subunit 4
- ATP synthase subunit gamma
- ATP synthase subunit delta, mitochondrial
- F1F0 ATP synthase subunit g
- ATP synthase subunit d
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0005215 (transporter activity), GO:0140657 (ATP-dependent activity), GO:0016887 (ATP hydrolysis activity), GO:0016874 (ligase activity), GO:0016787 (hydrolase activity), GO:0022857 (transmembrane transporter activity), GO:0046933 (proton-transporting ATP synthase activity, rotational mechanism), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0015267 (channel activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0005261 (monoatomic cation channel activity), GO:0016462 (pyrophosphatase activity), GO:0015078 (proton transmembrane transporter activity), GO:0015252 (proton channel activity), GO:0017111 (ribonucleoside triphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0019637 (organophosphate metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0006793 (phosphorus metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0006753 (nucleoside phosphate metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0019693 (ribose phosphate metabolic process), GO:0018130 (heterocycle biosynthetic process), GO:0090407 (organophosphate biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0072521 (purine-containing compound metabolic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0009259 (ribonucleotide metabolic process), GO:0009141 (nucleoside triphosphate metabolic process), GO:0009117 (nucleotide metabolic process), GO:0046390 (ribose phosphate biosynthetic process), GO:0006163 (purine nucleotide metabolic process), GO:0072522 (purine-containing compound biosynthetic process), GO:1901293 (nucleoside phosphate biosynthetic process), GO:0009165 (nucleotide biosynthetic process), GO:0009144 (purine nucleoside triphosphate metabolic process), GO:0006164 (purine nucleotide biosynthetic process), GO:0009150 (purine ribonucleotide metabolic process), GO:0009260 (ribonucleotide biosynthetic process), GO:0009199 (ribonucleoside triphosphate metabolic process), GO:0009142 (nucleoside triphosphate biosynthetic process), GO:0009201 (ribonucleoside triphosphate biosynthetic process), GO:0009152 (purine ribonucleotide biosynthetic process), GO:0046034 (ATP metabolic process), GO:0009145 (purine nucleoside triphosphate biosynthetic process), GO:0009205 (purine ribonucleoside triphosphate metabolic process), GO:0006754 (ATP biosynthetic process), GO:0009206 (purine ribonucleoside triphosphate biosynthetic process), GO:0015986 (proton motive force-driven ATP synthesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)