Protein: Luteinizing hormone/choriogonadotropin receptor (E7ESK4)
Organism: Homo sapiens (Human)
Subcellular location: Cell membrane; Multi-pass membrane protein
Sequence: MKQRFSALQLLKLLLLLQPPLPRALREALCPEPCNCVPDGALRCPGPTAGLTRLSLAYLPVKVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFINLPRLKYLSICNTGIRKFPDVTKVFSSESNFILEICDNLHITTIPGNAFQGMNNESVTLKLYGNGFEEVQSHAFNGTTLTSLELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSYGLESIQRLIATSSYSLKKLPSRETFVNLLEATLTYPSHCCAFRNLPTKEQNFSHSISENFSKQCESTVRKVNNKTLLLHGALSAAHSLS
InterPro domains: - IPR026906: BspA-type LRR region (repeat) [61-240]
- IPR002273: Lutropin-choriogonadotropic hormone receptor (family) [30-256]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [33-321]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0051641 (cellular localization), GO:0065008 (regulation of biological quality), GO:0044237 (cellular metabolic process), GO:0055085 (transmembrane transport), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051234 (establishment of localization), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0003008 (system process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0044238 (primary metabolic process), GO:0033036 (macromolecule localization), GO:1901564 (organonitrogen compound metabolic process), GO:0010646 (regulation of cell communication), GO:0007186 (G protein-coupled receptor signaling pathway), GO:0006810 (transport), GO:0019538 (protein metabolic process), GO:0009966 (regulation of signal transduction), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0016043 (cellular component organization), GO:0050877 (nervous system process), GO:0051668 (localization within membrane), GO:0043170 (macromolecule metabolic process), GO:0090066 (regulation of anatomical structure size), GO:0045184 (establishment of protein localization), GO:0006793 (phosphorus metabolic process), GO:0036211 (protein modification process), GO:0032535 (regulation of cellular component size), GO:0007187 (G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger), GO:0043412 (macromolecule modification), GO:0071705 (nitrogen compound transport), GO:0015031 (protein transport), GO:0071702 (organic substance transport), GO:0006796 (phosphate-containing compound metabolic process), GO:0008104 (protein localization), GO:0007600 (sensory perception), GO:0090150 (establishment of protein localization to membrane), GO:0072657 (protein localization to membrane), GO:0016310 (phosphorylation), GO:0006812 (monoatomic cation transport), GO:0035296 (regulation of tube diameter), GO:0072659 (protein localization to plasma membrane), GO:0006468 (protein phosphorylation), GO:0050954 (sensory perception of mechanical stimulus), GO:0018193 (peptidyl-amino acid modification), GO:0007605 (sensory perception of sound), GO:0018105 (peptidyl-serine phosphorylation), GO:0018209 (peptidyl-serine modification)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)