wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Uncharacterized protein (A9CEW3)
Organism: Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
Function: Not known
Sequence: MIGRQGSRRLVQALDKAARAAGIRPGTPVSKAQALVPGLLVEDLDAAGDARALQQLAFHFLRIYAPIVAADPPDGLVLDTSGADHLHGNEALMLSSMLNRLHAAGFAARAAIADSWGAAHALARFSREEISIVPPGGQRAAISGLPLSALRLEDRIVSGLKVLGFRTIGELAEAPRAPLTLRFGPELVRRRSQAFGEIGDPIEPVRVAELVEVRRVFPEPIAAAETIARYSQKLVTALCASLEKRGLGARRVDLVLHRVDSGLQAIRAGTSRPVRDVKQLVRLLTDRIDTIDPGFGIEMMVLTATHAEPLVAAQARSSLLDEGRAEIADTVDVILNRGHRVYRYAAVASDVPERSLARVAALAPEDTLGWPGHWPRPVRLFARPEPIETLALLPDHPPRYFLWKGERHNVRRADGPERVFGEWWKRDREKAAVRDYFTVENEGGERFWIFRSGDGEHAETGSQGWFIHGVFA
InterPro domains: - IPR017961: DNA polymerase, Y-family, little finger domain (domain) [214-308]
- IPR050356: Bacterial Cell Division Inhibitor SulA (family) [28-472]
- IPR043502: DNA/RNA polymerase superfamily (homologous_superfamily) [4-201]
- IPR001126: UmuC domain (domain) [2-119]
- IPR045443: Domain of unknown function DUF6504 (domain) [396-468]
Interaction partners: - Damage-inducible protein
- Error-prone DNA polymerase 1
- Beta sliding clamp
- LexA repressor
- DNA polymerase I
- Probable peptidoglycan glycosyltransferase FtsW
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0006950 (response to stress), GO:0009991 (response to extracellular stimulus), GO:0071496 (cellular response to external stimulus), GO:0031668 (cellular response to extracellular stimulus), GO:0033554 (cellular response to stress), GO:0006974 (cellular response to DNA damage stimulus), GO:0009432 (SOS response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0140535 (intracellular protein-containing complex), GO:0005886 (plasma membrane), GO:0042575 (DNA polymerase complex), GO:1990234 (transferase complex), GO:0061695 (transferase complex, transferring phosphorus-containing groups)
Protein: Ubiquitin-conjugating enzyme E2 5A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 5A) (Ubiquitin carrier protein 5a) (OsUBC5a) (Ubiquitin-protein ligase 5A) (Q8S920)
Organism: Oryza sativa subsp. japonica (Rice)
Function: E2 conjugating enzyme that associates with the E3 ubiquitin-protein ligase EL5 to mediates ubiquitination of target proteins.
Sequence: MASKRIQKELKDLQKDPPTSCSAGPVGEDMFHWQATIMGPSDSPYAGGVFLVTIHFPPDYPFKPPKVAFRTKVFHPNINSNGSICLDILKDQWSPALTISKVLLSICSLLTDPNPDDPLVPEIAHMYKTDRHKYENTARTWTQRYAM
InterPro domains: - IPR023313: Ubiquitin-conjugating enzyme, active site (active_site) [74-89]
- IPR016135: Ubiquitin-conjugating enzyme/RWD-like (homologous_superfamily) [1-147]
- IPR000608: Ubiquitin-conjugating (UBC), catalytic core domain (domain) [1-147]
Interaction partners: - HECT-type E3 ubiquitin transferase
- HECT-type E3 ubiquitin transferase
- HECT-type E3 ubiquitin transferase
- Os05g0392000 protein
- Os05g0392050 protein
- Ubiquitin-ribosomal protein eL40y fusion protein
- Anaphase-promoting complex subunit 11
- Anaphase-promoting complex subunit 11
- Os10g0491801 protein
- Ubiquitin-ribosomal protein eS31z fusion protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0070647 (protein modification by small protein conjugation or removal), GO:0032446 (protein modification by small protein conjugation), GO:0016567 (protein ubiquitination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) (A0A060WX43)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Function: Not known
Sequence: MAEADIALIGLAVMGQNIILNMNDHGFVVCAYNRTVSKVHDFLANEAKGTKIIGAESLEDMVAKLKKPRRIVMLVKAGQAVDDFIDKLVPLLEAGDIIIDGGNSEYRDTTRRCKSLKEKNLLFVGSGVSGGEEGARYGPSLMPGGHKEAWPHIKEIFQSIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMDHDVMAQAFEDWNKTELDSFLIEITAGILKFRDTDGTHLLPKIRDAAGQKGTGKWTAISALEYGTPVTLIGEAVFARCLSALKDERVEASRSLAGPQGAKFNGDKASFLEDIRKALYASKIISYAQGFMLLRQAAKEFGWSLNYGAIALMWRGGCIIRSVFLGKIKEAFDRDAELQNLLLDTFFSNAVQDCQDSWRRAVSIGVQQGIPMPCFTTALSFYDGYRHDMLPANLLQAQRDYFGAHTYELLSNPGKYIHTNWTGHGGNVSSSSYNA
InterPro domains: - IPR008927: 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (homologous_superfamily) [178-473]
- IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [4-175]
- IPR006115: 6-phosphogluconate dehydrogenase, NADP-binding (domain) [5-164]
- IPR006183: 6-phosphogluconate dehydrogenase (family) [3-482]
- IPR006113: 6-phosphogluconate dehydrogenase, decarboxylating (family) [1-478]
- IPR013328: 6-phosphogluconate dehydrogenase, domain 2 (homologous_superfamily) [182-436]
- IPR006114: 6-phosphogluconate dehydrogenase, C-terminal (domain) [180-470]
- IPR006184: 6-phosphogluconate-binding site (binding_site) [254-266]
Interaction partners: - GDH/6PGL endoplasmic bifunctional protein
- Hexose-6-phosphate dehydrogenase
- Glucose-6-phosphate 1-dehydrogenase
- Glucose-6-phosphate 1-dehydrogenase
- Glucose-6-phosphate 1-dehydrogenase
- Transaldolase
- Transaldolase
- glucose-6-phosphate dehydrogenase
- Ribulose-phosphate 3-epimerase
- Transketolase N-terminal domain-containing protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:1901700 (response to oxygen-containing compound), GO:0009743 (response to carbohydrate), GO:0034284 (response to monosaccharide), GO:0009746 (response to hexose), GO:0009749 (response to glucose)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0042579 (microbody), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005777 (peroxisome)
Protein: Sideroflexin-2 (Q96NB2)
Organism: Homo sapiens (Human)
Function: Mitochondrial amino-acid transporter that mediates transport of serine into mitochondria. Involved in mitochondrial iron homeostasis by regulating heme biosynthesis.
Subcellular location: Mitochondrion inner membrane {ECO:0000269|PubMed:30442778}; Multi-pass membrane protein {ECO:0000255}. Mitochondrion outer membrane {ECO:0000269|PubMed:30570704}; Multi-pass membrane protein {ECO:0000255}.
Sequence: MEADLSGFNIDAPRWDQRTFLGRVKHFLNITDPRTVFVSERELDWAKVMVEKSRMGVVPPGTQVEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQLPGGMIITGFMLQFYRTMPAVIFWQWVNQSFNALVNYTNRNAASPTSVRQMALSYFTATTTAVATAVGMNMLTKKAPPLVGRWVPFAAVAAANCVNIPMMRQQELIKGICVKDRNENEIGHSRRAAAIGITQVVISRITMSAPGMILLPVIMERLEKLHFMQKVKVLHAPLQVMLSGCFLIFMVPVACGLFPQKCELPVSYLEPKLQDTIKAKYGELEPYVYFNKGL
InterPro domains: - IPR004686: Tricarboxylate/iron carrier (family) [8-322]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0005515 (protein binding), GO:0008514 (organic anion transmembrane transporter activity), GO:0005342 (organic acid transmembrane transporter activity), GO:0046943 (carboxylic acid transmembrane transporter activity), GO:0015171 (amino acid transmembrane transporter activity), GO:0015175 (neutral L-amino acid transmembrane transporter activity), GO:0022889 (serine transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0044237 (cellular metabolic process), GO:0055085 (transmembrane transport), GO:0044281 (small molecule metabolic process), GO:1990542 (mitochondrial transmembrane transport), GO:1903825 (organic acid transmembrane transport), GO:0006730 (one-carbon metabolic process), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:1905039 (carboxylic acid transmembrane transport), GO:0003333 (amino acid transmembrane transport), GO:0006865 (amino acid transport), GO:0015849 (organic acid transport), GO:0015711 (organic anion transport), GO:0015804 (neutral amino acid transport), GO:0046942 (carboxylic acid transport), GO:0032329 (serine transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005740 (mitochondrial envelope), GO:0019866 (organelle inner membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031966 (mitochondrial membrane), GO:0005743 (mitochondrial inner membrane)
Protein: Receptor-binding cancer antigen expressed on SiSo cells (Cancer-associated surface antigen RCAS1) (Estrogen receptor-binding fragment-associated gene 9 protein) (Q9D0V7)
Organism: Mus musculus (Mouse)
Function: May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Note=Predominantly located in the Golgi. {ECO:0000250}.
Sequence: MAITQFRLFKVCTCLATVFSFLKRLICRSGRGRKLSGDQITLPTTVDYSSVPKQTDVEEWTSWDEDAPTSVKIEGGNGNVATQQNSLEQLEPDYFKDMTPTIRKTQKIVIKKREPLNFGVPDGSTGFSSRLAATQDMPFIHQSSELGDLDTWQENSNAWEEEEDAAWQAEEVLRQQKIADREKRAAEQQRKKMEKEAQRLMKKEQNKIGVKLS
InterPro domains: - IPR017025: Cancer-associated antigen RCAS1 (family) [1-213]
Interaction partners: - Estrogen receptor
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport), GO:0006897 (endocytosis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0030141 (secretory granule), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle)
Protein: Transcription factor Sp9 (P0CG40)
Organism: Homo sapiens (Human)
Function: Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Sequence: MATSILGEEPRFGTTPLAMLAATCNKIGNTSPLTTLPESSAFAKGGFHPWKRSSSSCNLGSSLSGFAVATGGRGSGGLAGGSGAANSAFCLASTSPTSSAFSSDYGGLFSNSAAAAAAAAGVSPQEAGGQSAFISKVHTTAADGLYPRVGMAHPYESWYKSGFHSTLAAGEVTNGAASSWWDVHSSPGSWLEVQNPAGGLQSSLHSGAPQASLHSQLGTYNPDFSSLTHSAFSSTGLGSSAAAASHLLSTSQHLLAQDGFKPVLPSYSDSSAAVAAAAASAMISGAAAAAAGGSSARSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHIKTHNGGGGGKKGSDSDTDASNLETPRSESPDLILHDSGVSAARAAAAAAAAAAAAAAAASAGGKEAASGPNDS
InterPro domains: - IPR013087: Zinc finger C2H2-type (domain) [332-416]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [346-416]
Interaction partners: - Acrosomal protein SP-10
- Lipase member N
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048736 (appendage development), GO:0009790 (embryo development), GO:0035107 (appendage morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0035108 (limb morphogenesis), GO:0060173 (limb development), GO:0035113 (embryonic appendage morphogenesis), GO:0030326 (embryonic limb morphogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Lipid/polyisoprenoid-binding YceI-like domain-containing protein (O07742)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Not known
Sequence: MAHKTRREGRAGRSSEYSRGVSDAVWTLDASDGELVLRTGVVGRAARLGHRLTIAMTRWQALVNWSGTDPVAGELVAEVDSFEVMRGEGGVKGLSEPEKALVRANALKTLNASRFPHIRFTTEAIAQTGNGYRLTGKLHIRGKSREHVIDLHTEDLGAAWRISADTTVRQSNYGVKPYSLLMGSIRVADEVSVAFTAVRAKDD
InterPro domains: - IPR007372: Lipid/polyisoprenoid-binding, YceI-like (domain) [25-200]
- IPR036761: Lipid/polyisoprenoid-binding, YceI-like superfamily (homologous_superfamily) [24-201]
Interaction partners: - Probable oxidoreductase
- Thiamine-phosphate synthase
- Mycoketide-CoA synthase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: N-succinylarginine dihydrolase (EC 3.5.3.23) (P76216)
Organism: Escherichia coli (strain K12)
Function: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
Sequence: MNAWEVNFDGLVGLTHHYAGLSFGNEASTRHRFQVSNPRLAAKQGLLKMKALADAGFPQAVIPPHERPFIPVLRQLGFSGSDEQVLEKVARQAPHWLSSVSSASPMWVANAATIAPSADTLDGKVHLTVANLNNKFHRSLEAPVTESLLKAIFNDEEKFSVHSALPQVALLGDEGAANHNRLGGHYGEPGMQLFVYGREEGNDTRPSRYPARQTREASEAVARLNQVNPQQVIFAQQNPDVIDQGVFHNDVIAVSNRQVLFCHQQAFARQSQLLANLRARVNGFMAIEVPATQVSVSDTVSTYLFNSQLLSRDDGSMMLVLPQECREHAGVWGYLNELLAADNPISELKVFDLRESMANGGGPACLRLRVVLTEEERRAVNPAVMMNDTLFNALNDWVDRYYRDRLTAADLADPQLLREGREALDVLSQLLNLGSVYPFQREGGGNG
InterPro domains: - IPR007079: Succinylarginine dihydrolase (family) [1-441]
- IPR037031: Succinylarginine dihydrolase superfamily (homologous_superfamily) [1-447]
Interaction partners: - N-succinylglutamate 5-semialdehyde dehydrogenase
- Succinylglutamate desuccinylase
- Succinylornithine transaminase
- Arginine N-succinyltransferase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0043167 (ion binding), GO:0016787 (hydrolase activity), GO:0043169 (cation binding), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0016813 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines), GO:0046872 (metal ion binding), GO:0046914 (transition metal ion binding), GO:0030145 (manganese ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006520 (amino acid metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044282 (small molecule catabolic process), GO:1901575 (organic substance catabolic process), GO:0006082 (organic acid metabolic process), GO:0044248 (cellular catabolic process), GO:0016054 (organic acid catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0043436 (oxoacid metabolic process), GO:1901605 (alpha-amino acid metabolic process), GO:0009063 (amino acid catabolic process), GO:0019752 (carboxylic acid metabolic process), GO:1901606 (alpha-amino acid catabolic process), GO:0009064 (glutamine family amino acid metabolic process), GO:0046395 (carboxylic acid catabolic process), GO:0009065 (glutamine family amino acid catabolic process), GO:0006527 (arginine catabolic process), GO:0006525 (arginine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: 5-hydroxyisourate hydrolase (HIU hydrolase) (HIUHase) (EC 3.5.2.17) (U6C7K1)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Function: Not known
Sequence: THVLNTGMGVPGAHMALSLHRMDPSTSLWNLLTTGTTNDDGRCPGLITRETFTPAVYKIRFETGQYWGSLGETSFYPYVEIVFTITDHSQKFHVPLLCSRFSY
InterPro domains: - IPR023416: Transthyretin/hydroxyisourate hydrolase domain (domain) [1-103]
- IPR014306: Hydroxyisourate hydrolase (family) [1-103]
- IPR036817: Transthyretin/hydroxyisourate hydrolase domain superfamily (homologous_superfamily) [1-103]
- IPR000895: Transthyretin/hydroxyisourate hydrolase (family) [32-87]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0016812 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0022607 (cellular component assembly), GO:0043933 (protein-containing complex organization), GO:0065003 (protein-containing complex assembly), GO:0051259 (protein complex oligomerization), GO:0051260 (protein homooligomerization), GO:0051262 (protein tetramerization), GO:0051289 (protein homotetramerization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Ifr2p (A0A1D8PSE7)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Sequence: MKAAVVPESVTETKLAEVKEIPKPTIGDDQILIKAEAAAVNPTDWKHIVFQMSKPGDVIGSDVSGTVEEVGSKVTNFKKGDTVSSFIIGNISPDSGAFGEYVIAYPQATIKYDHSLSHSSATNSSTIKSYEGAASVTLGLSTIGISFSHYLNIGKHKKEGDSILIWGGATATGILAIQVAKLVYNLNVITTASPKNHAFLKELGADHTLDYNDPNVIENLKALGPIKFGLDTIANTTTFQGLYDATAGTPEVYLDSLLGLDGKSIKTDPSRENSVHWGYTLAYLCVIKEKSFGPTKFVQTPELVDDYLKWWNEVLPTFIGKIKHANLKILGDGLASANEALQLSRDSKVSAQKIVFTV
InterPro domains: - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [130-243]
- IPR020843: Enoylreductase domain (domain) [8-334]
- IPR013149: Alcohol dehydrogenase-like, C-terminal (domain) [172-246]
- IPR011032: GroES-like superfamily (homologous_superfamily) [11-173]
- IPR047122: Trans-enoyl reductase-like (family) [1-358]
- IPR013154: Alcohol dehydrogenase-like, N-terminal (domain) [27-109]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016903 (oxidoreductase activity, acting on the aldehyde or oxo group of donors), GO:0016620 (oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor), GO:0004030 (aldehyde dehydrogenase [NAD(P)+] activity), GO:0004029 (aldehyde dehydrogenase (NAD+) activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0019748 (secondary metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044550 (secondary metabolite biosynthetic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0046483 (heterocycle metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0018130 (heterocycle biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005576 (extracellular region), GO:0031012 (extracellular matrix), GO:0062039 (biofilm matrix), GO:0062040 (fungal biofilm matrix)