Protein: Cyclic nucleotide gated channel subunit alpha 2a isoform X1 (Q0GFG2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Multi- pass membrane protein
Sequence: MTCQLLLESMDLSPHRLSVKTSIEDESEPADCTFSRDQSICDDTSSELQRVATLEQQRLNSFRDRGALSRLVNMVVTLREWAHKSLQEEEERPDSFLERFRGPELQIATSRLSISRHDIQDGNTSAKTKKKSDVFILSPADDLYYRWLFVIASAVLYNWCFVVARACFNELQTRNFILWLFLDYLSDVIYILDTCVRLRTGFLEQGLLVKDLIKLRESYFHTLQFKLDLLSIIPTDLGYIVIGIHVPELRLNRLMRFSRLFEFFDRTETRTSYPNLFRICNLVLYILVIIHWNACIYFAISKSLGFGSDQWVYPNISDPKFGTLTRGYVYCLYWSTLTLTTIGEMPAPVQDEEYLFVVFDFLVGVLIFATIVGNVGAMISNMNATRAEFQGQIDAIKHYMKFRKVSKELEARVIKWFDYLWTNKKTIDEQDVLKNLPNKLRAEIAINVHLETLKKVRIFQDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGCLAVVADDGVTQYAHLTAGSCFGEISILNIRGSKMGNRRTANIRSIGYSDLFCLSKGDLMEAVMEYPDAKKVLEEKGRQILIKEGLLEEVEADGIGVEDIEKRVERMEDTIEILQTRFARLLAQYTATQQHLKQRLTTLECRTNHSGSGFLSDGNESTIDGDGTNSEVNIHL
InterPro domains: - IPR018490: Cyclic nucleotide-binding domain superfamily (homologous_superfamily) [385-577]
- IPR032406: Cyclic nucleotide-gated channel, C-terminal leucine zipper domain (domain) [574-642]
- IPR014710: RmlC-like jelly roll fold (homologous_superfamily) [450-585]
- IPR005821: Ion transport domain (domain) [145-385]
- IPR018488: Cyclic nucleotide-binding, conserved site (conserved_site) [485-546]
- IPR000595: Cyclic nucleotide-binding domain (domain) [458-582]
- IPR050866: Cyclic nucleotide-gated cation channel (family) [43-649]
Interaction partners: - Solute carrier family 12 member 8
- Dynein light chain Tctex-type 5
- Adenylate kinase isoenzyme 5
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0015267 (channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0006810 (transport), GO:0030030 (cell projection organization), GO:0006996 (organelle organization), GO:0006811 (monoatomic ion transport), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0044782 (cilium organization), GO:0060271 (cilium assembly), GO:0120031 (plasma membrane bounded cell projection assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0098590 (plasma membrane region), GO:0120025 (plasma membrane bounded cell projection), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0005798 (Golgi-associated vesicle), GO:0031253 (cell projection membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0005929 (cilium), GO:0098588 (bounding membrane of organelle), GO:0031982 (vesicle), GO:0030659 (cytoplasmic vesicle membrane), GO:0012506 (vesicle membrane), GO:0060170 (ciliary membrane), GO:0030660 (Golgi-associated vesicle membrane), GO:0097708 (intracellular vesicle)