Protein: Protein pal1 (Pears and lemons protein 1) (Q9UU83)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Involved in cellular morphogenesis and cell wall integrity. Important for the maintenance of a cylindrical cell shape.
Subcellular location: Cell membrane {ECO:0000269|PubMed:15975911}; Peripheral membrane protein {ECO:0000269|PubMed:15975911}. Note=Localizes to cell tips during interphase and to the medial ring during mitosis and cytokinesis.
Sequence: MMVIENPFLSTATSSQTPQEDGVYTSSLHNSNNPFLAPKTERVADPVMESMADDLFNSIQKKKEPSPASSASASPVKKSAEALAERSNSSMGTFDPPPRYSKIARARSTHVASSSRHRSPSHNDSSPSTQSSLKSRGSIRRYKSVREGSHRPGRSSKEPLDQIDRLDVTGLYGSGSFHHDGPFDACRPHRNRNSKKAPVAAFPKDSIANSIPKVGETYNDPSVPKDFSRKAIHESLRTKNILQSPYKSVGIEEEFPSSGNNDTPGLTDSTRIEGAMASKNAIARNEEMLAMEKAGLGRKNSLIRKLGLNRSASMMSRTPNTLNRPSNYRSHSSMGTRRSPLNSPSQLDPISNENESDTDDSNTGLRNRTSPTAAPPPPSRRKTGGLNTRPYPQHAESQMSLPLTAKERSKPKKMGFFRRLFHKKS
InterPro domains: - IPR013226: Pal1 cell morphology (family) [2-425]
Interaction partners: - Endocytosis protein end4
- PH and SEC7 domain-containing protein C11E3.11c
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0008047 (enzyme activator activity), GO:0060589 (nucleoside-triphosphatase regulator activity), GO:0030695 (GTPase regulator activity), GO:0005096 (GTPase activator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0051641 (cellular localization), GO:0023057 (negative regulation of signaling), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051234 (establishment of localization), GO:0023051 (regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0051050 (positive regulation of transport), GO:0048585 (negative regulation of response to stimulus), GO:0033036 (macromolecule localization), GO:0048522 (positive regulation of cellular process), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:1903829 (positive regulation of protein localization), GO:0051049 (regulation of transport), GO:0046907 (intracellular transport), GO:0032388 (positive regulation of intracellular transport), GO:0010646 (regulation of cell communication), GO:0060341 (regulation of cellular localization), GO:0006810 (transport), GO:0009966 (regulation of signal transduction), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0060627 (regulation of vesicle-mediated transport), GO:0051222 (positive regulation of protein transport), GO:0045184 (establishment of protein localization), GO:0031348 (negative regulation of defense response), GO:0006886 (intracellular protein transport), GO:0090316 (positive regulation of intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0032386 (regulation of intracellular transport), GO:1904951 (positive regulation of establishment of protein localization), GO:0015031 (protein transport), GO:0070201 (regulation of establishment of protein localization), GO:0071702 (organic substance transport), GO:0051169 (nuclear transport), GO:0032880 (regulation of protein localization), GO:0008104 (protein localization), GO:1902531 (regulation of intracellular signal transduction), GO:0006913 (nucleocytoplasmic transport), GO:0032006 (regulation of TOR signaling), GO:0006611 (protein export from nucleus), GO:0032007 (negative regulation of TOR signaling), GO:0046824 (positive regulation of nucleocytoplasmic transport), GO:0033157 (regulation of intracellular protein transport), GO:0046822 (regulation of nucleocytoplasmic transport), GO:0034504 (protein localization to nucleus), GO:0051170 (import into nucleus), GO:0051168 (nuclear export)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0032153 (cell division site), GO:0005829 (cytosol), GO:0030427 (site of polarized growth), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0060187 (cell pole), GO:0051286 (cell tip), GO:0120025 (plasma membrane bounded cell projection), GO:0043332 (mating projection tip), GO:0043229 (intracellular organelle), GO:0005938 (cell cortex), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005937 (mating projection), GO:0005634 (nucleus)