Protein: Tryptophanyl-tRNA synthetase (G3V277)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSYKAAAGEDYKADCPPGNPAPTSNHGPDATEAEEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHHFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAY
InterPro domains: - IPR014729: Rossmann-like alpha/beta/alpha sandwich fold (homologous_superfamily) [76-212]
- IPR001412: Aminoacyl-tRNA synthetase, class I, conserved site (conserved_site) [164-174]
- IPR000738: WHEP-TRS domain (domain) [8-68]
- IPR009068: uS15/NS1, RNA-binding domain superfamily (homologous_superfamily) [9-64]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0009628 (response to abiotic stimulus), GO:0023056 (positive regulation of signaling), GO:0009058 (biosynthetic process), GO:0042221 (response to chemical), GO:0048584 (positive regulation of response to stimulus), GO:0019222 (regulation of metabolic process), GO:0051240 (positive regulation of multicellular organismal process), GO:0006807 (nitrogen compound metabolic process), GO:0051239 (regulation of multicellular organismal process), GO:0071704 (organic substance metabolic process), GO:0009892 (negative regulation of metabolic process), GO:0050793 (regulation of developmental process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0009893 (positive regulation of metabolic process), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0006950 (response to stress), GO:0051094 (positive regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0044238 (primary metabolic process), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0045597 (positive regulation of cell differentiation), GO:0001666 (response to hypoxia), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0070482 (response to oxygen levels), GO:0009966 (regulation of signal transduction), GO:0060255 (regulation of macromolecule metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901700 (response to oxygen-containing compound), GO:0006520 (amino acid metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0010033 (response to organic substance), GO:1901360 (organic cyclic compound metabolic process), GO:2000026 (regulation of multicellular organismal development), GO:0006139 (nucleobase-containing compound metabolic process), GO:0010646 (regulation of cell communication), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0006082 (organic acid metabolic process), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0045595 (regulation of cell differentiation), GO:0010647 (positive regulation of cell communication), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0071456 (cellular response to hypoxia), GO:0009059 (macromolecule biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0006753 (nucleoside phosphate metabolic process), GO:0006518 (peptide metabolic process), GO:0071453 (cellular response to oxygen levels), GO:0051246 (regulation of protein metabolic process), GO:0071310 (cellular response to organic substance), GO:0043436 (oxoacid metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0051248 (negative regulation of protein metabolic process), GO:1901342 (regulation of vasculature development), GO:0045766 (positive regulation of angiogenesis), GO:0010628 (positive regulation of gene expression), GO:0050769 (positive regulation of neurogenesis), GO:0051960 (regulation of nervous system development), GO:0030177 (positive regulation of Wnt signaling pathway), GO:0031060 (regulation of histone methylation), GO:0010468 (regulation of gene expression), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0036293 (response to decreased oxygen levels), GO:0018130 (heterocycle biosynthetic process), GO:0036293 (response to decreased oxygen levels), GO:0010563 (negative regulation of phosphorus metabolic process), GO:0051247 (positive regulation of protein metabolic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0045765 (regulation of angiogenesis), GO:0010467 (gene expression), GO:0010629 (negative regulation of gene expression), GO:0051174 (regulation of phosphorus metabolic process), GO:0016070 (RNA metabolic process), GO:0031399 (regulation of protein modification process), GO:0031400 (negative regulation of protein modification process), GO:0043039 (tRNA aminoacylation), GO:0019220 (regulation of phosphate metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0036294 (cellular response to decreased oxygen levels), GO:0032774 (RNA biosynthetic process), GO:0097659 (nucleic acid-templated transcription), GO:0045936 (negative regulation of phosphate metabolic process), GO:0042325 (regulation of phosphorylation), GO:0001933 (negative regulation of protein phosphorylation), GO:0001932 (regulation of protein phosphorylation), GO:0042326 (negative regulation of phosphorylation), GO:0006351 (DNA-templated transcription), GO:0034660 (ncRNA metabolic process), GO:0036293 (response to decreased oxygen levels), GO:0006399 (tRNA metabolic process), GO:0098781 (ncRNA transcription), GO:0016074 (sno(s)RNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)