Protein: Growth hormone (Q0QBH4)
Organism: Ovis aries (Sheep)
Function: Not known
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU003618}.
Sequence: MMAAGPRTSLLLAFTLLCLLWTQVVGAFPAMSLSCLFANAVLRAQHLHQLAADTFKEFERTYIPEGQRYSIQNTQVAFCFSETIPAPTSKNEAQQKSDLELLRISLLLIQSWLGPLQFLSRVFTNSLVFGTSDRVYEKLKDLEEGILALMRELEDVTPRAGQILKQTYDKFDTNMRSDDALLKNYSLLSCFRKDLHKTETYLRVMKCRRFGEASCAF
InterPro domains: - IPR018116: Somatotropin hormone, conserved site (conserved_site) [79-207]
- IPR034975: Somatotropin (family) [36-215]
- IPR001400: Somatotropin/prolactin (family) [8-215]
- IPR009079: Four-helical cytokine-like, core (homologous_superfamily) [28-217]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0016791 (phosphatase activity), GO:0019203 (carbohydrate phosphatase activity), GO:0050308 (sugar-phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0042592 (homeostatic process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0019222 (regulation of metabolic process), GO:0032879 (regulation of localization), GO:0051050 (positive regulation of transport), GO:0048878 (chemical homeostasis), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0065009 (regulation of molecular function), GO:0006950 (response to stress), GO:0048522 (positive regulation of cellular process), GO:0050801 (monoatomic ion homeostasis), GO:0044093 (positive regulation of molecular function), GO:0051049 (regulation of transport), GO:0032409 (regulation of transporter activity), GO:0006970 (response to osmotic stress), GO:0034762 (regulation of transmembrane transport), GO:0034764 (positive regulation of transmembrane transport), GO:0098771 (inorganic ion homeostasis), GO:0043462 (regulation of ATP-dependent activity), GO:0031325 (positive regulation of cellular metabolic process), GO:0032411 (positive regulation of transporter activity), GO:0043270 (positive regulation of monoatomic ion transport), GO:0031323 (regulation of cellular metabolic process), GO:0010765 (positive regulation of sodium ion transport), GO:2000377 (regulation of reactive oxygen species metabolic process), GO:0010960 (magnesium ion homeostasis), GO:0034765 (regulation of monoatomic ion transmembrane transport), GO:0009651 (response to salt stress), GO:0055074 (calcium ion homeostasis), GO:0006972 (hyperosmotic response), GO:0034767 (positive regulation of monoatomic ion transmembrane transport), GO:0043268 (positive regulation of potassium ion transport), GO:0055080 (monoatomic cation homeostasis), GO:0055078 (sodium ion homeostasis), GO:0032414 (positive regulation of ion transmembrane transporter activity), GO:0022898 (regulation of transmembrane transporter activity), GO:0043269 (regulation of monoatomic ion transport), GO:2000379 (positive regulation of reactive oxygen species metabolic process), GO:0032781 (positive regulation of ATP-dependent activity), GO:1903406 (regulation of P-type sodium:potassium-exchanging transporter activity), GO:0090322 (regulation of superoxide metabolic process), GO:1903408 (positive regulation of P-type sodium:potassium-exchanging transporter activity), GO:1904064 (positive regulation of cation transmembrane transport), GO:2000651 (positive regulation of sodium ion transmembrane transporter activity), GO:0032412 (regulation of monoatomic ion transmembrane transporter activity), GO:0042538 (hyperosmotic salinity response), GO:0010959 (regulation of metal ion transport), GO:1902307 (positive regulation of sodium ion transmembrane transport), GO:0032930 (positive regulation of superoxide anion generation), GO:1904062 (regulation of monoatomic cation transmembrane transport), GO:1901381 (positive regulation of potassium ion transmembrane transport), GO:1901018 (positive regulation of potassium ion transmembrane transporter activity), GO:1901016 (regulation of potassium ion transmembrane transporter activity), GO:0032928 (regulation of superoxide anion generation), GO:1902305 (regulation of sodium ion transmembrane transport), GO:1901379 (regulation of potassium ion transmembrane transport), GO:2000649 (regulation of sodium ion transmembrane transporter activity), GO:0043266 (regulation of potassium ion transport), GO:0002028 (regulation of sodium ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)