Protein: Pyruvate carboxylase (EC 6.4.1.1) (Q8JHF6)
Organism: Gallus gallus (Chicken)
Function: Not known
Sequence: MSQLCVPRGGRALLGAWRLPLLRPPPGSVRSASCQPIRKVLVANRGEIAIRVFRACTELGLRTVAVYSEQDTGQMHRQKADEAYLVGRGLPPVQAYLHVPDIIRVARENAVDAIHPGYGFLSERADFAQACVDAGVRFVGPPPEVVRKMGDKVEARSIAIAAGVPVVPGTSAPVATLGEAQDFAARVGFPIIFKAAHGGGGRGMRAVRGPQELEESFSRASSEALAAFGDGALFVEKLMERPRHIEGQILGDKHGNVVHLYERDCSIQRRHQKVVEIAPAARLDPQLRAQLASDAVRIAQQVGYENAGTVEFLVDRDGKHYFIEVNSRLQVEHTVTEEITGVDLVQAQLLVAAGRSLSELGLQQDSVRVNGCAIQCRVTTEDPARGFQPDTGRIEVFRSGEGMGIRLDGASAFQGALISPHYDSLLVKVIAHGPDQPSAAAKMSRALGEFRIRGVKTNIPFLQNVLAHPQFLGGAVDTQFIDENPELFHLRPSQNRAQKLLHYLGHVMVNGPSTPLPVKAKAAVVEPVPPPVPMGSPPEGLRAVLQREGPAGFARALRGHRGLLLXDTTFRDAHQSLLATRVRTRDLARIAPFVAHSLSPLCSMETWGGATFDVAMRFLHECPWERLRELRRLVPNIPFQMLLRGANAVGYTNYPDNVIYRFCEVAAANGMDIFRIFDALNYLPNLLLGVEAVGRAGAVVEAALSYTGDVADPTRTKYSLDYYLGLAKELVAAGTHILCIKDMAGLLTPAAARLLVSSLRDRFPDVPIHVHTHDTAGAAIATLLAAANADADVVDVAVDAMSGMTSQPSMGALVACARGTPLDTGIALERVFEYSEYWEGARGLYAAFDCTATMKSGNADVYENEIPGGQYTNLHFQAHAMGLGHKFKEVKKAYAEANKLLGDLIKVTPSSKVVGDLAQFMVQNGLSREEAEARADELSFPLSVVEFLQGYIGTPPGGFPEPFRSKVLKDLPRVEGRPGASLPPLDFEALSQELGARDGTPPSPEDLLSAALYPKVYAEFRDFTSTFGPVSCLGTRLFLEGPTIAEEFEVELERGKTLHIKALALGDLNAAGQREAFFELNGQLRSILVRDTQALKEMHVHPKADRSAKGQVGAPMPGEVVEVRVKEGEAVEKGAPLCVLSAMKMETVVTAPRGGTVSRLHVRPGMSLEGDDLIAEIE
InterPro domains: - IPR005481: Biotin carboxylase-like, N-terminal domain (domain) [37-145]
- IPR016185: Pre-ATP-grasp domain superfamily (homologous_superfamily) [34-149]
- IPR000089: Biotin/lipoyl attachment (domain) [1109-1178]
- IPR005482: Biotin carboxylase, C-terminal (domain) [375-483]
- IPR005930: Pyruvate carboxylase (family) [32-1178]
- IPR011761: ATP-grasp fold (domain) [156-353]
- IPR005479: Carbamoyl phosphate synthase, ATP-binding domain (domain) [151-359]
- IPR055268: Pyruvate carboxylase-like (family) [30-1178]
- IPR011764: Biotin carboxylation domain (domain) [36-486]
- IPR003379: Carboxylase, conserved domain (domain) [861-1061]
- IPR013785: Aldolase-type TIM barrel (homologous_superfamily) [516-1037]
- IPR000891: Pyruvate carboxyltransferase (domain) [563-835]
- IPR011054: Rudiment single hybrid motif (homologous_superfamily) [370-489]
- IPR011053: Single hybrid motif (homologous_superfamily) [1099-1178]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016874 (ligase activity), GO:0016885 (ligase activity, forming carbon-carbon bonds)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044283 (small molecule biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0006082 (organic acid metabolic process), GO:0019637 (organophosphate metabolic process), GO:0005996 (monosaccharide metabolic process), GO:0005975 (carbohydrate metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901575 (organic substance catabolic process), GO:0006091 (generation of precursor metabolites and energy), GO:1901135 (carbohydrate derivative metabolic process), GO:0006793 (phosphorus metabolic process), GO:0006753 (nucleoside phosphate metabolic process), GO:0019318 (hexose metabolic process), GO:0046364 (monosaccharide biosynthetic process), GO:0006757 (ATP generation from ADP), GO:0043436 (oxoacid metabolic process), GO:0019693 (ribose phosphate metabolic process), GO:0016051 (carbohydrate biosynthetic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0072521 (purine-containing compound metabolic process), GO:0016052 (carbohydrate catabolic process), GO:0009259 (ribonucleotide metabolic process), GO:0006006 (glucose metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0009141 (nucleoside triphosphate metabolic process), GO:0009117 (nucleotide metabolic process), GO:0006096 (glycolytic process), GO:0009132 (nucleoside diphosphate metabolic process), GO:0006163 (purine nucleotide metabolic process), GO:0019319 (hexose biosynthetic process), GO:0016310 (phosphorylation), GO:0009185 (ribonucleoside diphosphate metabolic process), GO:0006165 (nucleoside diphosphate phosphorylation), GO:0009135 (purine nucleoside diphosphate metabolic process), GO:0046939 (nucleotide phosphorylation), GO:0009144 (purine nucleoside triphosphate metabolic process), GO:0032787 (monocarboxylic acid metabolic process), GO:0009150 (purine ribonucleotide metabolic process), GO:0009199 (ribonucleoside triphosphate metabolic process), GO:0006094 (gluconeogenesis), GO:0046034 (ATP metabolic process), GO:0046031 (ADP metabolic process), GO:0009205 (purine ribonucleoside triphosphate metabolic process), GO:0006090 (pyruvate metabolic process), GO:0009179 (purine ribonucleoside diphosphate metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)