Protein: Anion exchange protein (Q9VM31)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Basolateral cell membrane {ECO:0000256|ARBA:ARBA00004554}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004554}. Membrane {ECO:0000256|RuleBase:RU362035}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU362035}.
Sequence: MAEKNEYIELPWTMNSSSGDDEAPKDPRTGGEDFTQQFTENDFEGHRAHTVYVGVHVPGGRRHSQRRRKHHHSGPGGGGGGGGGGGSIGGSGSVGGGAGKDNVSEKQQEVERPVTPPAQRVQFILGEDVDDGTHVSHPLFSEMGMLVKEGDEIEWKETARWIKFEEDVEEGGNRWSKPHVATLSLHSLFELRRLLVNGSVMLDMEAQNLEVMADLVCDHMVSAGTLPPGVKDKVKDALLRRHRHQHEYAKKTRLPIIRSLADMRNHSSSKKKKSNSKHSRPAQNLSSITEDMVKSPSNQSMARPGSGTELSEQQHKGNTHFMRKIPPGAEASNILVGEVDFLERTLSCFIRLSQAVVLGDLTEVPVPTRFVFILLGPPGSQSNFHEIGRAMATLMSDEIFHEVAYRARKRDHLLSGVDEFLDAVTVLPPGEWDPTIRIEPPAAIPSQEVRKRPPELPKEEVDEEEEEARLREENGLSRTGRLFGGLINDIKRKAPWYISDYKDALSMQCVASWIFLYFACLSPIITFGGLLAEATGKHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGWDYMTFRFWIGMWVAGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQGIYDCVCTPPIGSNASVIDYAKYNWDSCESYNGTLVGGDCGTPPTENVFLMSVVLCAGTFLISTVLKEFKNALFFPSIVRQYISDFSVLIAIFAMSFFDYSLGVPTQKLEVPNELKPTLSTRGWLIPPFVEKNPWWSAIIAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFILSILIAICSMMGLPWFVAATVLSINHVNSLKLESECSAPGEKPQFLGVREQRVTHILIFLTIGVSVLLTPLLGNIPMPVLFGVFLYMGVASLKGLQFFDRILIMFMPAKYQPDYMFLRQVPIKRVHLFTMIQLACLIILWLIKSFSQTSILFPLMLVVMIGIRKALDLVFTRRELKILDDIMPEMTKRAAADDLHKLDAEVGLLARIFPWGKGSRSRVVTKPPGLDDGIVGSGGAVGAGLITCTTSNANEKEFEAQSSLLKK
InterPro domains: - IPR013769: Band 3 cytoplasmic domain (domain) [138-434]
- IPR011531: Bicarbonate transporter-like, transmembrane domain (domain) [481-1020]
- IPR003020: Bicarbonate transporter, eukaryotic (family) [134-1026]
- IPR016152: Phosphotransferase/anion transporter (homologous_superfamily) [134-461]
- IPR003024: Sodium bicarbonate cotransporter (family) [168-617]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0022853 (active monoatomic ion transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0015106 (bicarbonate transmembrane transporter activity), GO:0015081 (sodium ion transmembrane transporter activity), GO:0015291 (secondary active transmembrane transporter activity), GO:0015293 (symporter activity), GO:0140410 (solute:bicarbonate symporter activity), GO:0015294 (solute:monoatomic cation symporter activity), GO:0046873 (metal ion transmembrane transporter activity), GO:0015370 (solute:sodium symporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0007267 (cell-cell signaling), GO:0023051 (regulation of signaling), GO:0042221 (response to chemical), GO:0007154 (cell communication), GO:0050794 (regulation of cellular process), GO:0099536 (synaptic signaling), GO:0099177 (regulation of trans-synaptic signaling), GO:0010646 (regulation of cell communication), GO:0046685 (response to arsenic-containing substance), GO:0050804 (modulation of chemical synaptic transmission), GO:0099537 (trans-synaptic signaling), GO:0032228 (regulation of synaptic transmission, GABAergic), GO:0098916 (anterograde trans-synaptic signaling), GO:0007268 (chemical synaptic transmission), GO:0007271 (synaptic transmission, cholinergic)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)