Protein: Sprouty-related protein with EVH-1 domain, isoform C (A0A0B4KG11)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MTEGHESDFLVTVRAQVMTRDESTEGWLPLAGGGLANVSIRKRARLSPLASGHDYIIYGQRISDQSVILSCVINRDLKYYKVMPTFHHWRAGKQRNGLTFQTAADARAFDKGVLRAYNELIDGLAKSNPTIICPPLTKYDSVGEDDVFMTLDLPVESESLQKIHSSPEGSEKSHKSVSNNSDSEKLPPPPIHYISTDKTSATTSPPDAPPASAAPSPATAGQIAASENYSYVTLTAVHHDYNYPVVDQPVGAQVLNARRESISALKKRNALEAAQAMAAAQTAAGGGLACRDGGSGKPLHKPNVSDILKKETRLRCRYCHELYSEDFNRRGACEYAPDAFRSGYECISGMGCARCMIYHCMSDAEGETAQHPCDCSASEAGCSKRWLGLAILSLFVPCLWCYPPLRACHLAGIHCGLCGGQHKPHVXHLEARLQGQHDDDPRPRSEFHYHHSEQSIMNSAKRPWGAKQKQSQQSQQSQRHFYNWELSHSLGAPQHQTPPYLMQSTGRKAPQNDYGRLLF
InterPro domains: - IPR000697: WH1/EVH1 domain (domain) [1-120]
- IPR041937: SPRE, EVH1 domain (domain) [9-122]
- IPR007875: Sprouty (family) [313-424]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [1-128]
Interaction partners: - Neurofibromin 1, isoform B
- Ras-like protein 1
- Titin
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0023057 (negative regulation of signaling), GO:0009653 (anatomical structure morphogenesis), GO:0007389 (pattern specification process), GO:0051241 (negative regulation of multicellular organismal process), GO:0051239 (regulation of multicellular organismal process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0009791 (post-embryonic development), GO:0050793 (regulation of developmental process), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0051093 (negative regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0048609 (multicellular organismal reproductive process), GO:0048585 (negative regulation of response to stimulus), GO:0007276 (gamete generation), GO:0048736 (appendage development), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0002165 (instar larval or pupal development), GO:0007552 (metamorphosis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009966 (regulation of signal transduction), GO:0035107 (appendage morphogenesis), GO:0009887 (animal organ morphogenesis), GO:0009888 (tissue development), GO:0003002 (regionalization), GO:0010646 (regulation of cell communication), GO:0045596 (negative regulation of cell differentiation), GO:0045595 (regulation of cell differentiation), GO:0009886 (post-embryonic animal morphogenesis), GO:0045879 (negative regulation of smoothened signaling pathway), GO:0045664 (regulation of neuron differentiation), GO:0035120 (post-embryonic appendage morphogenesis), GO:0048707 (instar larval or pupal morphogenesis), GO:0035114 (imaginal disc-derived appendage morphogenesis), GO:1902532 (negative regulation of intracellular signal transduction), GO:0008589 (regulation of smoothened signaling pathway), GO:0030855 (epithelial cell differentiation), GO:0048737 (imaginal disc-derived appendage development), GO:0002064 (epithelial cell development), GO:0048569 (post-embryonic animal organ development), GO:0048563 (post-embryonic animal organ morphogenesis), GO:0007560 (imaginal disc morphogenesis), GO:0007444 (imaginal disc development), GO:0060429 (epithelium development), GO:1902531 (regulation of intracellular signal transduction), GO:0007478 (leg disc morphogenesis), GO:0007480 (imaginal disc-derived leg morphogenesis), GO:0035218 (leg disc development), GO:0007476 (imaginal disc-derived wing morphogenesis), GO:0007472 (wing disc morphogenesis), GO:0035220 (wing disc development), GO:0007476 (imaginal disc-derived wing morphogenesis), GO:0043409 (negative regulation of MAPK cascade), GO:0070373 (negative regulation of ERK1 and ERK2 cascade), GO:0070372 (regulation of ERK1 and ERK2 cascade)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)