wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Proton myo-inositol cotransporter (H(+)-myo-inositol cotransporter) (Hmit) (H(+)-myo-inositol symporter) (Solute carrier family 2 member 13) (Q96QE2)
Organism: Homo sapiens (Human)
Function: H(+)-myo-inositol cotransporter. Can also transport related stereoisomers.
Subcellular location: Cell membrane {ECO:0000269|PubMed:11500374}; Multi-pass membrane protein {ECO:0000269|PubMed:11500374}.
Sequence: MSRKASENVEYTLRSLSSLMGERRRKQPEPDAASAAGECSLLAAAESSTSLQSAGAGGGGVGDLERAARRQFQQDETPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSPRITFKPIAPSGQNATCTRYSYCNECMLDPDCGFCYKMNKSTVIDSSCVPVNKASTNEAAWGRCENETKFKTEDIFWAYNFCPTPYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNRLCTCGTSDSDEGRYIEYIRVKGSNYHLSDNDASDVE
InterPro domains: - IPR036259: MFS transporter superfamily (homologous_superfamily) [73-615]
- IPR020846: Major facilitator superfamily domain (domain) [84-598]
- IPR005829: Sugar transporter, conserved site (conserved_site) [180-397]
- IPR050814: Myo-inositol Transporter (family) [45-618]
- IPR003663: Sugar/inositol transporter (family) [78-545]
- IPR005828: Major facilitator, sugar transporter-like (family) [84-609]
Interaction partners: - Major facilitator superfamily
- Sodium/myo-inositol cotransporter
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0005515 (protein binding), GO:1901618 (organic hydroxy compound transmembrane transporter activity), GO:0015166 (polyol transmembrane transporter activity), GO:0005365 (myo-inositol transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0015850 (organic hydroxy compound transport), GO:0015798 (myo-inositol transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Lectin29Ca (Q6GUW9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MYKYATCIFSIFALWNFWGVSAKKRDTSTGTNELPKAPMPYYTIENIDMHQQHWFTYNSLRQNGTLWRIGNMEQRLEMRLQSFQNQMETQLRALKQQIEPYMENVKMSNKIKMSVFKKIGSRHFYLEKQKKMPWDSAYDTCRQMGGHLANILDEKELNEIFSEETKKNYWVDINSRANDGASWISTLSGRDVPFLKWKPNLATNIHRHCVYINSNEMYFENCANDNYFACQAEQWA
InterPro domains: - IPR001304: C-type lectin-like (domain) [109-231]
- IPR016186: C-type lectin-like/link domain superfamily (homologous_superfamily) [59-234]
- IPR016187: C-type lectin fold (homologous_superfamily) [119-232]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:0030246 (carbohydrate binding), GO:0097367 (carbohydrate derivative binding), GO:0005515 (protein binding), GO:0048029 (monosaccharide binding), GO:0005537 (mannose binding)
Biological Process (BP): GO:0008150 (biological process), GO:0000003 (reproduction), GO:0019953 (sexual reproduction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Probable protein phosphatase 2C 69 (AtPP2C69) (EC 3.1.3.16) (Q8LAY8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MGYLDLALSYSNQPQTVEAPASGGGLSQNGKFSYGYASSAGKRSSMEDFFETRIDGINGEIVGLFGVFDGHGGARAAEYVKRHLFSNLITHPKFISDTKSAITDAYNHTDSELLKSENSHNRDAGSTASTAILVGDRLVVANVGDSRAVISRGGKAIAVSRDHKPDQSDERERIENAGGFVMWAGTWRVGGVLAVSRAFGDRLLKQYVVADPEIQEEKIDDTLEFLILASDGLWDVFSNEAAVAMVKEVEDPEDSAKKLVGEAIKRGSADNITCVVVRFLEKKSASSSHISSSSSKEAKEMPPLGDLAISSNEAKQVQIGSGNKPENVTNRKPDTASRSTDTLTLERNSVTDKV
InterPro domains: - IPR036457: PPM-type phosphatase-like domain superfamily (homologous_superfamily) [25-306]
- IPR000222: PPM-type phosphatase, divalent cation binding (binding_site) [64-72]
- IPR015655: Protein phosphatase 2C (family) [28-279]
- IPR001932: PPM-type phosphatase-like domain (domain) [23-279]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0004721 (phosphoprotein phosphatase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0004722 (protein serine/threonine phosphatase activity), GO:0016791 (phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0006950 (response to stress), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006807 (nitrogen compound metabolic process), GO:0044238 (primary metabolic process), GO:0006952 (defense response), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043207 (response to external biotic stimulus), GO:0043170 (macromolecule metabolic process), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0006793 (phosphorus metabolic process), GO:0036211 (protein modification process), GO:0006796 (phosphate-containing compound metabolic process), GO:0043412 (macromolecule modification), GO:0042742 (defense response to bacterium), GO:0016311 (dephosphorylation), GO:0006470 (protein dephosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: CMP-sialic acid transporter 4 (CMP-SA-Tr 4) (CMP-Sia-Tr 4) (F4JN00)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Sugar transporter involved in the transport of CMP-sialic acid from the cytoplasm into the Golgi (By similarity). Essential protein.
Subcellular location: Golgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Sequence: MEYRKIKDEDDHDVASDIESVKGKSHTVASSNIAMATLGVGSSERINWKRKGVVTCALTILTSSQAILIVWSKRAGKYEYSVTTANFLVGTLKCALSLLALTRIWKNEGVTDDNRLSTTFDEVKVFPIPAALYLFKNLLQYYIFAYVDAPGYQILKNLNIISTGVLYRIILKRKLSEIQWAGFILLCCGCTTAQLNSNSDRVLQTSLPGWTMAIVMALLSGFAGVYTEAIIKKRPSRNINVQNFWLYVFGMAFNAVAIVIQDFDAVANKGFFHGYSFITLLMILNHALSGIAVSMVMKYADNIVKVYSTSVAMLLTAVVSVFLFNFHLSLAFFLGSTVVSVSVYLHSAGKLR
InterPro domains: - IPR037185: Multidrug transporter EmrE superfamily (homologous_superfamily) [118-197]
- IPR007271: Nucleotide-sugar transporter (family) [30-351]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015932 (nucleobase-containing compound transmembrane transporter activity), GO:1901505 (carbohydrate derivative transmembrane transporter activity), GO:0005338 (nucleotide-sugar transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0015849 (organic acid transport), GO:0015711 (organic anion transport), GO:0046942 (carboxylic acid transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Anaerobic dimethyl sulfoxide reductase chain C (DMSO reductase anchor subunit) (P18777)
Organism: Escherichia coli (strain K12)
Function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. DmsC anchors the DmsAB dimer to the membrane and stabilizes it.
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Sequence: MGSGWHEWPLMIFTVFGQCVAGGFIVLALALLKGDLRAEAQQRVIACMFGLWVLMGIGFIASMLHLGSPMRAFNSLNRVGASALSNEIASGSIFFAVGGIGWLLAMLKKLSPALRTLWLIVTMVLGVIFVWMMVRVYNSIDTVPTWYSIWTPMGFFLTMFMGGPLLGYLLLSLAGVDGWAMRLLPAISVLALVVSGVVSVMQGAELATIHSSVQQAAALVPDYGALMSWRIVLLAVALCLWIAPQLKGYQPAVPLLSVSFILLLAGELIGRGVFYGLHMTVGMAVAS
InterPro domains: - IPR007059: DMSO reductase anchor subunit (DmsC) (family) [1-286]
Interaction partners: - Anaerobic dimethyl sulfoxide reductase chain B
- Dimethyl sulfoxide reductase DmsA
- Tat proofreading chaperone DmsD
- Putative dimethyl sulfoxide reductase chain YnfE
- Probable dimethyl sulfoxide reductase chain YnfF
- Probable anaerobic dimethyl sulfoxide reductase chain YnfG
- Biotin sulfoxide reductase
- Hydrogenase-2 operon protein HybA
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016661 (oxidoreductase activity, acting on other nitrogenous compounds as donors), GO:0016662 (oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006520 (amino acid metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044282 (small molecule catabolic process), GO:1901575 (organic substance catabolic process), GO:0006082 (organic acid metabolic process), GO:0044248 (cellular catabolic process), GO:0016054 (organic acid catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0043436 (oxoacid metabolic process), GO:1901605 (alpha-amino acid metabolic process), GO:0009063 (amino acid catabolic process), GO:0019752 (carboxylic acid metabolic process), GO:1901606 (alpha-amino acid catabolic process), GO:0009064 (glutamine family amino acid metabolic process), GO:0046395 (carboxylic acid catabolic process), GO:0009065 (glutamine family amino acid catabolic process), GO:0006560 (proline metabolic process), GO:0006527 (arginine catabolic process), GO:0006525 (arginine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: SIT4 phosphatase-associated family protein (F4I6B2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MFWRMAGLSTASAVEAILDKDSFTLEDLLDEDEIIQECKALNGRLLNFLREKVQVEQLIRYIIEEPLEDVEKKRTFKFPFIACEIFTCEIEMILKTLVEDEELMLLLFSFLEAKETHNSLLAGYFSKVVICLLVRKTIPFMQFIKDHQEILKQLVDLIGITSIMEVLKRLVGTDEHLYSNYTSAMQWIEDTDVLEMIVDKFGSSESPEVHANAAEILCTVARYAPPGLATKLSSPSCTGRLLKHTLEDSRPKSVLVNSLSVCISLLDPKRFTLGTYHIYGRQLTHGSMVTNPETVEGMLGSLGDLLMLLNVSSAEGVLLTTYGKLQPPLGKHRLKIVEFISVLLTVGSEAAEKEVIRLGAVKRVLDLFFEYPYNNFLHHHVENVILSCMESKNSQLVDHLLSECNLIGSILEAEKDSTLTAGDSDKLQPTVPAEGKKPLRIGNIGHLTRISNKLLQLANSNVEIQSHLQENSKWVDWQTDVLSKRNTLENVYSWACGRPTSLHDRSRDSDDDDYHDRDYDVAALANNLSQAFRYGIYSNDDMDEAQGSMERDDEDVYFDDESAEVVISSLRLGDDQESDSLFTNSNWFAFDDDKAANERSMTSAASPSPNADGDGEDDDDVVIGEADEFNATAASSPPVDMETEDSTSKHPSENPSEPEPEKSPAWVEWRETSESTAPPSSNPEETTILSNGDVQIEKEDNDDDDDTDNKSAVKTPGVPGDETTEKLPDESGVEPTENSPKASGIEPTESSPKASGAEVTGNLRDSDPAESHADAKSSEPESPHGTKETEVAAEADTKETEEAVKEPEKVV
InterPro domains: - IPR016024: Armadillo-type fold (homologous_superfamily) [166-461]
- IPR007587: SIT4 phosphatase-associated protein family (family) [1-738]
Interaction partners: - Phytochrome-associated serine/threonine-protein phosphatase 1
- Phytochrome-associated serine/threonine-protein phosphatase 3
- P-loop containing nucleoside triphosphate hydrolases superfamily protein
- F6D8.10
- Tapetal oleosin GRP-17
- Receptor-like protein 51
- Serine/threonine-protein phosphatase BSL1
- Serine/threonine-protein phosphatase BSU1
- Serine/threonine-protein phosphatase BSL2
- Protein RER1A
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0065009 (regulation of molecular function), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0050790 (regulation of catalytic activity), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051246 (regulation of protein metabolic process), GO:0051336 (regulation of hydrolase activity), GO:0051174 (regulation of phosphorus metabolic process), GO:0010921 (regulation of phosphatase activity), GO:0031399 (regulation of protein modification process), GO:0019220 (regulation of phosphate metabolic process), GO:0043666 (regulation of phosphoprotein phosphatase activity), GO:0035303 (regulation of dephosphorylation), GO:0035304 (regulation of protein dephosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Actin-binding LIM protein 1 (A0A8I5ZVV8)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Sequence: MPSFLGLRCLEKLCSSEKGKGPSPERASLRGSHGRRLVIEDLSVPETPHPARHRHGTVTYLFYLYSSNRGPPELRFSSCDSSVAHPQDPHHSSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGDYLCTLDYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKEATCSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEYISKDGSPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYEDKQDRQSLGESPRTLSPTPSAEGFQDGRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHAALAAQNKASEDIIKFSKFPAAQAPDPNEIPKIETDHWPGPPSLAAIGTDPRRRSSGREEDEEELLRRRQLQEEQLMKLNSGLGQLILKEEMEKENRERASLLASRYDSPLHSASHAPSSKTSSLPGYGKSGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPKIFPYEMLMVTNRGRNKILRDVDRTRLERHLAPEVFWEIFGMSIQEFDKLPLWRRNDMKKKAKLF
InterPro domains: - IPR032402: Putative adherens-junction anchoring domain (domain) [350-729]
- IPR051618: Actin-binding LIM (family) [90-779]
- IPR003128: Villin headpiece (domain) [711-779]
- IPR001781: Zinc finger, LIM-type (domain) [98-337]
- IPR036886: Villin headpiece domain superfamily (homologous_superfamily) [701-779]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0016043 (cellular component organization), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0022008 (neurogenesis), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0120036 (plasma membrane bounded cell projection organization), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098794 (postsynapse), GO:0030054 (cell junction), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0099572 (postsynaptic specialization), GO:0043228 (non-membrane-bounded organelle), GO:0098984 (neuron to neuron synapse), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0014069 (postsynaptic density), GO:0098978 (glutamatergic synapse), GO:0032279 (asymmetric synapse), GO:0005856 (cytoskeleton), GO:0015629 (actin cytoskeleton)
Protein: WRKY transcription factor WRKY76 (OsWRKY76) (Q6IEK5)
Organism: Oryza sativa subsp. indica (Rice)
Function: Transcription repressor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Regulates, probably indirectly, the activation of defense-related genes during defense response (By similarity). Modulates plant innate immunity against X.oryzae pv. oryzae (Xoo) (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q6QHD1, ECO:0000255|PROSITE-ProRule:PRU00223}.
Sequence: MDAAWRGGVGCSPVCLDLCVGLSPVREPSAARHELLDRPAGCRGGGDSKSMTNDEAKILEAKVTQMSEENRRLTEVIARLYGGQIARLGLDGSASPPRPVSPLSGKKRSRESMETANSCDANSNRHQGGDADHAESFAADDGTCRRIKVSRVCRRIDPSDTSLVVKDGYQWRKYGQKVTRDNPSPRAYFRCAFAPSCPVKKKVQRSAEDSSLLVATYEGEHNHPHPSPRAGELPAAVGGAGGSLPCSISINSSGPTITLDLTKNGGAVQVVEAAHPPPPPDLKEVCREVASPEFRTALVEQMASALTSDPKFTGALAAAILQKLPEF
InterPro domains: - IPR044810: WRKY transcription factor, plant (family) [53-322]
- IPR003657: WRKY domain (domain) [160-226]
- IPR036576: WRKY domain superfamily (homologous_superfamily) [152-227]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0003682 (chromatin binding), GO:0003700 (DNA-binding transcription factor activity), GO:1990841 (promoter-specific chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:1901700 (response to oxygen-containing compound), GO:0043207 (response to external biotic stimulus), GO:0010033 (response to organic substance), GO:0009620 (response to fungus), GO:0009617 (response to bacterium), GO:0014070 (response to organic cyclic compound), GO:0009751 (response to salicylic acid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: N-alpha-acetyltransferase 35, NatC auxiliary subunit (Embryonic growth-associated protein) (zEGAP) (Protein MAK10 homolog) (Q7T322)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Regulates cell proliferation during embryonic development. May be involved in acetylating the N-terminus of mtor.
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:Q5VZE5}.
Sequence: MVMKSSVEEEEGGWGLGIPEKMRNNANWVDVTQEFKGACKELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFDQAVKDEAIRVKDLSIPELIGIMDTCFCCLITWLEGHSLAQTVFTCLYVHNPDLIQDPALKAFALGILKICDIAREKVNKAAVFEEEDFQAMTYGFKMANNVTDLRVTGMLKDVEDELQRKVKSTRSRQGEQRDPEVELDHQQCLALFSRVKFTRLLLSALISFTKKETSAVSEAQKLMSQAADLLPAVHATIQYGIQSQNDTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFSKLIERIKSVCEVINITNLHSILDFFCEFSEQSPCVLSRSLLQTTFLIDNKKVFGTHLMQDMIKDALRCFVSPPVLSSKCSLNNNHQAKDYIDSFVTHCTRPFCSLIQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHGLLMKLEPQRQHLACLGTWILYHNLRIMIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRADSSQMAEERILEEQLKVRSSKKSKKKKKARPLSKEITMSQAYQNMCAGMYKTMIALDMDRKVRKPQFELDSEQVRYEHRFAPFNSVVTPPPVHYIQFKEMSDLKKYNPPPRSADLYMAASKHFQQAKLLLENVTSPDAEVNRILKVAKPNIVVMKLLAGGHKKETKALPEFDFSAHKYFPIVKIL
InterPro domains: - IPR007244: NAA35-like (family) [21-723]
- IPR057982: NAA35-like, TPR repeats (domain) [338-721]
- IPR057983: NAA35-like, N-terminal (domain) [45-188]
Interaction partners: - N-alpha-acetyltransferase 38, NatC auxiliary subunit
- N-alpha-acetyltransferase 30
- Small nuclear ribonucleoprotein E
- N-alpha-acetyltransferase 50
- N
- PHD finger protein 20, b
- Zinc finger protein 710
- N-terminal amino-acid N
- N-alpha-acetyltransferase 20
- DALR anticodon-binding domain-containing protein 3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0030097 (hemopoiesis), GO:0048863 (stem cell differentiation), GO:0002244 (hematopoietic progenitor cell differentiation), GO:0060216 (definitive hemopoiesis), GO:0060218 (hematopoietic stem cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0140535 (intracellular protein-containing complex), GO:0031248 (protein acetyltransferase complex), GO:1990234 (transferase complex), GO:1902493 (acetyltransferase complex)