Protein: CDK-activating kinase assembly factor MAT1 (CDK7/cyclin-H assembly factor) (Menage a trois) (RING finger protein MAT1) (A0A8I6ATM4)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR003338}.
Sequence: MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLENTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQESEQRRLFIQKEEELQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKSMKPVTFSTGIKMGSLISLAPIQKLEEALYEYQPLQIETCGPQVPEQELLGRLGKVMVEGVTEINS
InterPro domains: - IPR017907: Zinc finger, RING-type, conserved site (conserved_site) [26-35]
- IPR004575: Cdk-activating kinase assembly factor MAT1/Tfb3 (family) [1-278]
- IPR003903: Ubiquitin interacting motif (conserved_site) [142-161]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [1-65]
- IPR015877: MAT1, centre (domain) [53-250]
- IPR001841: Zinc finger, RING-type (domain) [3-50]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0007049 (cell cycle), GO:0048523 (negative regulation of cellular process), GO:0022402 (cell cycle process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0044770 (cell cycle phase transition), GO:1903047 (mitotic cell cycle process), GO:0042127 (regulation of cell population proliferation), GO:0060548 (negative regulation of cell death), GO:0010941 (regulation of cell death), GO:0000278 (mitotic cell cycle), GO:0008284 (positive regulation of cell population proliferation), GO:0048660 (regulation of smooth muscle cell proliferation), GO:0048661 (positive regulation of smooth muscle cell proliferation), GO:0044772 (mitotic cell cycle phase transition), GO:0044843 (cell cycle G1/S phase transition), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:0043066 (negative regulation of apoptotic process), GO:0042981 (regulation of apoptotic process), GO:0000082 (G1/S transition of mitotic cell cycle)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0140535 (intracellular protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:1902494 (catalytic complex), GO:0140513 (nuclear protein-containing complex), GO:0005667 (transcription regulator complex), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0030880 (RNA polymerase complex), GO:0032806 (carboxy-terminal domain protein kinase complex), GO:0043233 (organelle lumen), GO:0055029 (nuclear DNA-directed RNA polymerase complex), GO:1990234 (transferase complex), GO:0016591 (RNA polymerase II, holoenzyme), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0090575 (RNA polymerase II transcription regulator complex), GO:0000428 (DNA-directed RNA polymerase complex), GO:0043231 (intracellular membrane-bounded organelle), GO:0005675 (transcription factor TFIIH holo complex), GO:0070013 (intracellular organelle lumen), GO:0061695 (transferase complex, transferring phosphorus-containing groups), GO:0031981 (nuclear lumen), GO:1902911 (protein kinase complex), GO:0005634 (nucleus), GO:1902554 (serine/threonine protein kinase complex), GO:0000307 (cyclin-dependent protein kinase holoenzyme complex)