Protein: Putative nucleotidyltransferase MAB21L1 (Q6NYB4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Putative nucleotidyltransferase required for several aspects of embryonic development including normal development of the eye (By similarity). It is unclear whether it displays nucleotidyltransferase activity in vivo. Binds single-stranded RNA (ssRNA) (By similarity)
Subcellular location: Nucleus
Sequence: MIAAQAKLVYHLNKYYNEKCQSRKAAISKTIREVCKVVSDVLKEVEVQEPRFISSLNEMDNRFEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECYSLNGKQSSAESDAWVLQFAEAENRLLLGGCRKKCLSLLKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDENCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL
InterPro domains: - IPR024810: MAB21L/Cyclic GMP-AMP synthase-like receptor (family) [61-347]
- IPR046903: Mab-21-like, nucleotidyltransferase domain (domain) [63-243]
- IPR046906: Mab-21-like, HhH/H2TH-like domain (domain) [246-343]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0060900 (embryonic camera-type eye formation), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0048729 (tissue morphogenesis), GO:0002088 (lens development in camera-type eye), GO:0009888 (tissue development), GO:0002089 (lens morphogenesis in camera-type eye), GO:0048731 (system development), GO:0061303 (cornea development in camera-type eye), GO:0048513 (animal organ development), GO:0009790 (embryo development), GO:1904888 (cranial skeletal system development), GO:0060041 (retina development in camera-type eye), GO:0048705 (skeletal system morphogenesis), GO:0048568 (embryonic organ development), GO:0007399 (nervous system development), GO:0001501 (skeletal system development), GO:0048562 (embryonic organ morphogenesis), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0048484 (enteric nervous system development), GO:0090596 (sensory organ morphogenesis), GO:0002072 (optic cup morphogenesis involved in camera-type eye development), GO:0048701 (embryonic cranial skeleton morphogenesis), GO:0009792 (embryo development ending in birth or egg hatching), GO:0002009 (morphogenesis of an epithelium), GO:0060429 (epithelium development), GO:0016331 (morphogenesis of embryonic epithelium), GO:0048483 (autonomic nervous system development), GO:0043009 (chordate embryonic development), GO:0002011 (morphogenesis of an epithelial sheet), GO:0048592 (eye morphogenesis), GO:0001654 (eye development), GO:0048704 (embryonic skeletal system morphogenesis), GO:0048048 (embryonic eye morphogenesis), GO:0031076 (embryonic camera-type eye development), GO:0061386 (closure of optic fissure), GO:0150063 (visual system development), GO:0048706 (embryonic skeletal system development), GO:0043010 (camera-type eye development), GO:0048593 (camera-type eye morphogenesis), GO:0048596 (embryonic camera-type eye morphogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)