Protein: [histone H3]-trimethyl-L-lysine(27) demethylase (A0A8M3AU53)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
Sequence: MHHTAEQFTGCSTRDPFPLDGLNRGPWAPVGSRAWPPPSRCLTGVNQHQLLPHMPSHMTGLNHPSKFLNNGPIHRGDKQDQSQALMPALQRMPPAPPRPWDPTRAGQGYEPLPGDNHNRLRNSYNAGPPSHLTARANQLLKFGAPHPQLATHGSRPIHPLPDLWTPPENQQQPRGTHSNSGQLKRPGPPLGEHSVIQHTPPPSLHRPIEDLPSPSKRKKSSGSEQIAHSAMQRLSGPTVHLNQQPSSHYPPPKPGFWNPLHKVGAPWNPTEHKSGPIHFQDSAKPEVESIPYKAPPISLSTLSSPTINTTSGYGQSRASSSQSQKATQSPQSLGPPLQSPHIHHSAYSYSNNRPSDQSQGEPHGTTPQRGHHLDTPPPLIPKFSASLRADRERPAPSPANHTTVPYSHPQFQPHPGLVHSTSPPASNQAKATVPQHNLHKPWRNQESHDCAGTGVSQIAARHSQAHNSVVGNQGPRTPQHVSPPQASARKPVITPNLETPHPPCSLKPYTSVGSIPTMSSAPLTTSSIHSTLSIGRPTDSSVLMSNPNHLSMIGQNPPHLGYQGVHPGVGTLPHLHGVQSQIQQSTLTHTGQSRPNYTPVSSTPSTLNSGLQRSGDSVITSKPSNTLPQPVSSPLSCPHPPAQIKANSILQPMSSRSYNSVTTESSSSISQATTTVPTPVYPGSSLQPTVPCSIADAFNKLDAELQGHMQAEERKRQQEEKRKQIVEKQEVNTKPHCESAIRSLERLLSGNTTEPPPPRLSPANAPSSISPSSQNSPPYPWLSRGGVPPRPSGISATIIEQSQPPPLTPQTEYAREKQRQREKLKSGTPSQNSTGISTYHSESTLISTSNHNMQLKPDPSKDFMLKTAQNIGIIGAIPNPPPLREQPKLYQAFHKDANPSCTLISMTENNLQKQIPSAGLQGLGSNASSCSGDSDGAQFEEETSELLPDGLANIMKMLDESIKKEEELYSGQKGEQAVSELQFSTNVAPVKSYLCAPDLVPALKQSPAEDYQPDGHASPPVLSRQGSLASPCSRTSSLEEEEEVLASSLKVIPKSANSNSVLSQDGSLATTGTNYRHSDLAKLYGISEVVKSECEDDEDEVDREDETPSCSPPQRPHLHQTGVNSMFKNLASVLESQKYTYRGGPFGRPPRSAFVGVKYSSSLSLGPDICRQQQSTSPTSGSASHPGFSSPTQTSAISNSGQTCPLSPTSCESESKRGDKISPSDLLGNDDEKDISEEPKVKVDSGNMKDLLERRPKLTTISESSLAELGQSLEVNKHIIPFKDHSKAEAREICKPVEEKERHRDRERERKHKHSSSSKKHEDKKERKKKHRERHDDASLSSSSSSSSSRRHRDGKSHKEKKSRQVLGNLDLQSKELREKEQERDGDKKRRKEESGRPQNEGEAWTQIREKGSSSGHSSDLPSGSSALCSDDFQKLKALTDGPPKELKIRLIKVESGDRETFIASEVEEKRIPLKDITIKNSASEIIRACKAARVKGKFKESYLLDAFSVKPVVRTELPIPREKLNPPTPSIYLESKRDAFSPVLLQFCTDPKNPITVIRGLAGSLRLNLGLFSTKSLVEANSEHAVEVRTQVQQPADENWDASGTGQTWPCESSRSHTTIAKYAQYQASSFQESLQEEKGSDAEEDNDEKPTTKAESTTSNSSAPNSSSEQKTVGKIIKFGTNIDLSDPKRWKPQLQELQKLPAFMRVSSSGNMLSHVGHTILGMNTVQLYMKIPGCRTPGHQENNNFCSVNINIGPGDCEWFAVHDDYWEAISDFCQKHGVDYLTGSWWPVLDDLYRANIPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPVNAYQYQVALERFEWNEVKKVKSIVPMIHVSWNVARTVKVTDPDAYNMIKHCLLQSIKHIQILRDQLVAAGMKISYQSRVKDEPAYYCNECDVEVFNLLFVTSENGSRKMYVVHCEDCARQRSPNLSNVVVLEQYRMEELMNMYDSFSLAVSPSSR
InterPro domains: - IPR048560: Lysine-specific demethylase 6A/B-like, GATA-like (domain) [1917-1977]
- IPR003347: JmjC domain (domain) [1692-1855]
- IPR048562: Lysine-specific demethylase 6A/B-like, C-terminal helical domain (domain) [1845-1899]
- IPR051630: Transcriptional Corepressor and Histone Demethylase (family) [931-1990]
- IPR046941: Lysine-specific demethylase 6, GATA-like domain superfamily (homologous_superfamily) [1910-1976]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009887 (animal organ morphogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0060042 (retina morphogenesis in camera-type eye), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0003407 (neural retina development), GO:0060041 (retina development in camera-type eye), GO:0022008 (neurogenesis), GO:0007399 (nervous system development), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0090596 (sensory organ morphogenesis), GO:0060219 (camera-type eye photoreceptor cell differentiation), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0042461 (photoreceptor cell development), GO:0042670 (retinal cone cell differentiation), GO:0048592 (eye morphogenesis), GO:0001654 (eye development), GO:0048699 (generation of neurons), GO:0046530 (photoreceptor cell differentiation), GO:0150063 (visual system development), GO:0043010 (camera-type eye development), GO:0048593 (camera-type eye morphogenesis), GO:0001754 (eye photoreceptor cell differentiation), GO:0042462 (eye photoreceptor cell development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)