wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Uncharacterized ABC transporter ATP-binding protein YphE (P77509)
Organism: Escherichia coli (strain K12)
Function: Probably part of a binding-protein-dependent transport system YphDEF. Probably responsible for energy coupling to the transport system
Sequence: MFTATEAVPVAKVVAGNKRYPGVVALDNVNFTLNKGEVRALLGKNGAGKSTLIRMLTGSERPDSGDIWIGETRLEGDEATLTRRAAELGVRAVYQELSLVEGLTVAENLCLGQWPRRNGMIDYLQMAQDAQRCLQALGVDVSPEQLVSTLSPAQKQLVEIARVMKGEPRVVILDEPTSSLASAEVELVISAVKKMSALGVAVIYVSHRMEEIRRIASCATVMRDGQVAGDVMLENTSTHHIVSLMLGRDHVDIAPVAPQEIVDQAVLEVRALRHKPKLEDISFTLRRGEVLGIAGLLGAGRSELLKAIVGLEEYEQGEIVINGEKITRPDYGDMLKRGIGYTPENRKEAGIIPWLGVDENTVLTNRQKISANGVLQWSTIRRLTEEVMQRMTVKAASSETPIGTLSGGNQQKVVIGRWVYAASQILLLDEPTRGVDIEAKQQIYRIVRELAAEGKSVVFISSEVEELPLVCDRILLLQHGTFSQEFHAPVNVDELMSAILSVH
InterPro domains: - IPR003593: AAA+ ATPase domain (domain) [35-480]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [7-498]
- IPR050107: ABC transporter carbohydrate import ATP-binding proteins (family) [9-501]
- IPR017871: ABC transporter-like, conserved site (conserved_site) [405-419]
- IPR003439: ABC transporter-like, ATP-binding domain (domain) [8-499]
Interaction partners: - Probable ABC transporter permease protein YphD
- ABC transporter periplasmic-binding protein YphF
- Autoinducer 2 import system permease protein LsrC
- Ribose import permease protein RbsC
- D-allose transport system permease protein AlsC
- L-arabinose transport system permease protein AraH
- L-arabinose transport system permease protein AraH
- Galactose/methyl galactoside import permease protein MglC
- Autoinducer 2 import system permease protein LsrD
- Autoinducer 2 import system permease protein LsrD
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0044238 (primary metabolic process), GO:0055085 (transmembrane transport), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0005996 (monosaccharide metabolic process), GO:0005975 (carbohydrate metabolic process), GO:0034219 (carbohydrate transmembrane transport), GO:0006810 (transport), GO:0015749 (monosaccharide transmembrane transport), GO:0071702 (organic substance transport), GO:0019321 (pentose metabolic process), GO:0008643 (carbohydrate transport), GO:0042732 (D-xylose metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: UPF0073 inner membrane protein YqfA (P67153)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell inner membrane; Multi-pass membrane protein
Sequence: MVQKPLIKQGYSLAEEIANSVSHGIGLVFGIVGLVLLLVQAVDLNASATAITSYSLYGGSMILLFLASTLYHAIPHQRAKMWLKKFDHCAIYLLIAGTYTPFLLVGLDSPLARGLMIVIWSLALLGILFKLTIAHRFKILSLVTYLAMGWLSLVVIYEMAVKLAAGSVTLLAVGGVVYSLGVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYIGQA
InterPro domains: - IPR004254: AdipoR/Haemolysin-III-related (family) [6-215]
- IPR005744: Hly-III (family) [15-216]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0043167 (ion binding), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0043169 (cation binding), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0052689 (carboxylic ester hydrolase activity), GO:0046872 (metal ion binding), GO:0046914 (transition metal ion binding), GO:0030145 (manganese ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0043933 (protein-containing complex organization), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly), GO:0051259 (protein complex oligomerization), GO:0051260 (protein homooligomerization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: UPF0114 protein YqhA (P67244)
Organism: Escherichia coli (strain K12)
Subcellular location: Cell membrane; Multi-pass membrane protein
Sequence: MERFLENAMYASRWLLAPVYFGLSLALVALALKFFQEIIHVLPNIFSMAESDLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISENKEKLNWLGKMDATSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLTRHNH
InterPro domains: - IPR005134: Uncharacterised protein family UPF0114 (family) [9-125]
- IPR020761: Uncharacterised protein family UPF0114, bacteria (family) [1-164]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0015267 (channel activity), GO:0015079 (potassium ion transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0005261 (monoatomic cation channel activity), GO:0005267 (potassium channel activity), GO:0046873 (metal ion transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0034220 (monoatomic ion transmembrane transport), GO:0098660 (inorganic ion transmembrane transport), GO:0006810 (transport), GO:0098655 (monoatomic cation transmembrane transport), GO:0098662 (inorganic cation transmembrane transport), GO:0006811 (monoatomic ion transport), GO:0071805 (potassium ion transmembrane transport), GO:0006812 (monoatomic cation transport), GO:0030001 (metal ion transport), GO:0006813 (potassium ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Transcription factor ZEB2 (I1RFC6)
Organism: Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084
Function: Transcription factor that specifically controls transcription of the zearalenone biosynthesis cluster genes
Subcellular location: Nucleus
Sequence: MQSTESFHALPTRSDVEDPNERRKIQNRIAQKKHRQKMKRRIEELETKVNNQCQTSNWTSHAPTDSCQEQQFLDNTDFGLMLEDDLLYRELSASLDGAGLTAVAQMHDSPRPNQQQRLSVSGMPSSPTSTSNVAQRGLSIGDHSSASNHLSSLSLVPGSTEGSLPTRQHDNLCNQDLRDMVPEEKMSRILKVIQDAGYKDMDSFMTEYYVRDFDASSHVSAVQRQSRSRRLRGFLEQLRVGAESWSDYEAHDYQQEISKSAEAIYAKELDVFSTTTLGENASFQGLASLYRVLQSTVGSDIENHLRHEQSMMQRQVSEIVHRQVYTFNPAQC
InterPro domains: - IPR046347: Basic-leucine zipper domain superfamily (homologous_superfamily) [18-53]
- IPR052635: Secondary Metabolite Biosynthesis Regulator (family) [14-145]
- IPR004827: Basic-leucine zipper domain (domain) [22-37]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0019748 (secondary metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044550 (secondary metabolite biosynthetic process), GO:0044249 (cellular biosynthetic process), GO:0009404 (toxin metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044283 (small molecule biosynthetic process), GO:0046483 (heterocycle metabolic process), GO:0006082 (organic acid metabolic process), GO:0030638 (polyketide metabolic process), GO:1901334 (lactone metabolic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0043385 (mycotoxin metabolic process), GO:0009403 (toxin biosynthetic process), GO:0016053 (organic acid biosynthetic process), GO:0043436 (oxoacid metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0018130 (heterocycle biosynthetic process), GO:0030639 (polyketide biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0043386 (mycotoxin biosynthetic process), GO:1901336 (lactone biosynthetic process), GO:0046394 (carboxylic acid biosynthetic process), GO:0072330 (monocarboxylic acid biosynthetic process), GO:0032787 (monocarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Zinc-regulated GTPase metalloprotein activator 1 (O74310)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Zinc chaperone that directly transfers zinc cofactor to target metalloproteins, thereby activating them. Catalyzes zinc insertion into the active site of methionine aminopeptidase map1, which function to cleave the initiator methionine from polypeptides during or after protein translation. Mechanistically, the N-terminal psi-PxLVp motif binds to the C6H2-type zinc finger of inactive form of map1. After formation of the docked complex, zinc is transferred from the CXCC motif in the GTPase domain of zng1 to the zinc binding site in the peptidase domain of map1 in a process requiring GTP hydrolysis. GTP/GDP exchange is required for release of active map1
Sequence: MDFEIENESEIPQLVDVEEVNTQPHSETLSVPTVSSNNDIDSFEQQSDFLLVDHDSTLDPVPVTILTGFLGAGKTSLLRSILENRNGKRVAVLMNEVGDSGDLERSLMEDVGGEELYEEWVALSNGCMCCTVKDNGIKALEKIMRQKGRFDNIVIETTGIANPGPLAQTFWLDDALKSDVKLDGIVTVIDCKNIDNILKDESDIGFIQISHADCLILNKTDLISSEALSVVRQTILKINCLAKIIETTYGRLDDISEILDLDAYGNENTSNLEWSIQRSNDSNINCSTCLDVDCQHLHSLDTHSLDISTHTFKLPPLMSKEVFQQFLQWVRHTLWSCLEEGEDEEFMIYRSKGIFNKDDGSWYIFQGVREVFEIMPLSEKPRAFLEKDIHPEIILIGRNLHRISPFVVGNQ
InterPro domains: - IPR051316: Zinc-regulated GTPase metalloprotein activator (family) [55-402]
- IPR011629: Zinc chaperone CobW-like, C-terminal (domain) [307-411]
- IPR036627: CobW-like, C-terminal domain superfamily (homologous_superfamily) [290-404]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [58-268]
- IPR003495: CobW/HypB/UreG, nucleotide-binding domain (domain) [62-245]
Interaction partners: - General negative regulator of transcription subunit 2
- Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
- Methionine aminopeptidase 1
- Large ribosomal subunit protein bL28m
- Large ribosomal subunit protein bL33m
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140104 (molecular carrier activity), GO:0016530 (metallochaperone activity)
Biological Process (BP): GO:0008150 (biological process), GO:0042592 (homeostatic process), GO:0048878 (chemical homeostasis), GO:0019725 (cellular homeostasis), GO:0050801 (monoatomic ion homeostasis), GO:0055082 (intracellular chemical homeostasis), GO:0098771 (inorganic ion homeostasis), GO:0006873 (intracellular monoatomic ion homeostasis), GO:0006882 (intracellular zinc ion homeostasis), GO:0055080 (monoatomic cation homeostasis), GO:0030003 (intracellular monoatomic cation homeostasis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Protein zyg-11 homolog (Q5TYQ1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Serves as substrate adapter subunit in an E3 ubiquitin ligase complex zyg11-cul2-elongin BC. Targets substrates bearing N-terminal glycine degrons for proteasomal degradation
Sequence: MIHLSQTMDKSSLPSLSDLCMSLVSSRLELFCEMRDDGSLSFREPLVFPQELADQLLCKMATDGVLNDSTVGIFRNCQQFRLRHACIRTARISAEAFHRALCPHRLVELDASRVNADLTIADILRGLSSNKSLQESLQRLVLNGLTMSSLEEPSRRCFSAMQGLRALSVSNVDFYDWGLADVCLLPRLESLDISNTSVSNLTPLLGLRSRLRYLTMHQLKRLEMTTAQLLAVLSQLEVLQHLDISDDKQFTSDVARQLLETPGILPQLVSLDVSGRKQVTDAAVKAFVEARPGMTFVGLLATDAGFSEFLSGEGSLKVTGEANETQICEALRRYSEREGFVREALFHLFSLTHAIEKPRPDILKLVALGMKNHPTTLNVQLAASACVFNLTKQELAFGIPVRLLGNVTQQLLEAMKTFPNHQQLQKNCLLSLCSDRILQEVPFNRFEAAKLVMQWLCNHEDQNMQRMAVAIISILAAKLSTEQTAQLGAELFIVKQLLHIVRQKTCQSTVDATLKFTLSALWNLTDESPTTCRHFIENQGLELFIKVLESFPSESSIQQKVLGLLNNIAEVSELHGELMVQSFLDHIRTLLHSPEVEVSYFAAGILAHLTSRGEKVWTLELTLRNTLLQQLHSAILKWPTPECEMVAYRSFNPFFPLLECFQTPGVQLWAAWAMQHVCSKNAGRYCSMLLEEGGLQHLEAITSHPKTHSDVRRLTESILDGLQRHRARTGYTAIPKTQAHREKCNP
InterPro domains: - IPR016024: Armadillo-type fold (homologous_superfamily) [341-724]
- IPR011989: Armadillo-like helical (homologous_superfamily) [360-729]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [56-292]
- IPR055142: Protein zer-1 homolog-like, C-terminal domain (domain) [369-722]
- IPR000225: Armadillo (repeat) [480-611]
- IPR051341: Zyg-11-related ubiquitin ligase adapter protein (family) [14-709]
Interaction partners: - Cullin-2
- Elongin-C
- Elongin-C
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0071684 (organism emergence from protective structure), GO:0001824 (blastocyst development), GO:0009790 (embryo development), GO:0035188 (hatching), GO:0009792 (embryo development ending in birth or egg hatching), GO:0001835 (blastocyst hatching), GO:0043009 (chordate embryonic development), GO:0001701 (in utero embryonic development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0140535 (intracellular protein-containing complex), GO:1990234 (transferase complex), GO:0000151 (ubiquitin ligase complex), GO:0031461 (cullin-RING ubiquitin ligase complex), GO:0031462 (Cul2-RING ubiquitin ligase complex)
Protein: Histone H3 (B6JV95)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Subcellular location: Chromosome. Nucleus
Sequence: MARTKQTARKSTGGKAPRKQLASKAARKSAPPTTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAIGALQEAVEAYLVSLFEDTNLCAIHGKRVTIQPKDMQLARRLRGERS
InterPro domains: - IPR000164: Histone H3/CENP-A (family) [1-137]
- IPR009072: Histone-fold (homologous_superfamily) [2-137]
- IPR007125: Core Histone H2A/H2B/H3 domain (domain) [45-132]
Interaction partners: - Chromodomain protein Chp1
- RSC complex subunit Sfh1
- Histone H2B
- Histone H4
- Histone-lysine N-methyltransferase
- Histone-lysine N-methyltransferase, H3 lysine-36 specific
- Histone-lysine N-methyltransferase, H3 lysine-4 specific
- Histone H2A
- Histone acetyltransferase GCN5
- DNA-directed RNA polymerase subunit
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0007276 (gamete generation), GO:0007289 (spermatid nucleus differentiation), GO:0007281 (germ cell development), GO:0016043 (cellular component organization), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0007283 (spermatogenesis), GO:0035092 (sperm DNA condensation), GO:0048515 (spermatid differentiation), GO:0006325 (chromatin organization), GO:0007286 (spermatid development), GO:0006996 (organelle organization), GO:0048232 (male gamete generation), GO:0006997 (nucleus organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0032993 (protein-DNA complex), GO:0000785 (chromatin), GO:0098687 (chromosomal region), GO:0044815 (DNA packaging complex), GO:0000786 (nucleosome), GO:0043229 (intracellular organelle), GO:0000775 (chromosome, centromeric region), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome)
Protein: Calcium-transporting ATPase (A0A2H1A643)
Organism: Candidozyma auris (Yeast) (Candida auris)
Function: Catalyzes the hydrolysis of ATP coupled with the transport of calcium
Subcellular location: Endomembrane system; Multi-pass membrane protein. Membrane; Multi-pass membrane protein
Sequence: MSLISEKNPSRANTPSARFAQQSIKDTIAEFVTDAHLGLSNTQDILNRRSIHGDNELTHDEKESLVVKFFQAFNDPLILLLIGSAVISFWMGNVDDAVSISLAITIVVTVGFVQEYRSEKSLEALNRLVPAEAKLTRNGNTSTVLASHLVPGDLVHFSQGDRIPADVRLTDAVHLTIDESNLTGENDPVKKSANVNNPTDHTGDVSKDLPVTERSSIAFMGTLVRDGHGSGIVVATGGQTEFGTVFEMMSEIEKPKTPLQQAMDRLGKDLSVFSFGVIGTICLLGIIQGREWLDMFQISVSLAVAAIPEGLPIIVTVTLALGVLRMAKRKAIVRRLPSVETLGSVNVICSDKTGTLTQNHMTVTKIWSFDFQGSFNSPFLVVEKLDDSALHEKLTPNIRKVLEIGNVCNNARYSHESDKYVGNPSDIALLETLPHFSLEDVRGTKQRINEIPFSSDRKFMAVCAHSGDASRCETYVKGANEAILKLSDKYLDEQGNTKPLTEALKNHIHERAVALSSEGLRVLAFAKKSSKLTHDKDHTISSDLTFCGLVGMKDPPRPNVARSIAQLMKGGVHVIMITGDSPSTATNIARQIGIPISGKDSILTGDQLDRLSEESLSHAIHNVSVFARTTPEHKVTIVKALQRRGDVVAMTGDGVNDAPALKLADIGIAMGKNGTDVAKEAADMVLTDDDFSTILNAIEEGKGIFYNIQNFITFQLSTSIAALTLIALATFFGLPNPLNAMQILWINILMDGPPAQSLGVEPVDHEVMNKPPRKRNENILTQQVIKRVLQSAAMIILGTMYIFIKEMRDGQVTARDTTMTFTCFVLYDMFNALSCRHYTRSIFELGFDNNMFNLSVIGSLLGQMCAIYVPFFQAVFQTEALSFTDLVHLVFLTSTVFIADEIRKYLLRRRNQMINGYSYTYAV
InterPro domains: - IPR004014: Cation-transporting P-type ATPase, N-terminal (domain) [18-93]
- IPR006413: P-type ATPase, subfamily IIA, PMR1-type (family) [16-911]
- IPR023214: HAD superfamily (homologous_superfamily) [346-696]
- IPR036412: HAD-like superfamily (homologous_superfamily) [347-754]
- IPR044492: P-type ATPase, haloacid dehalogenase domain (domain) [331-702]
- IPR008250: P-type ATPase, A domain superfamily (homologous_superfamily) [130-249]
- IPR023299: P-type ATPase, cytoplasmic domain N (homologous_superfamily) [355-560]
- IPR018303: P-type ATPase, phosphorylation site (ptm) [351-357]
- IPR001757: P-type ATPase (family) [246-740]
- IPR006068: Cation-transporting P-type ATPase, C-terminal (domain) [735-906]
- IPR059000: P-type ATPase, A domain (domain) [128-249]
- IPR023298: P-type ATPase, transmembrane domain superfamily (homologous_superfamily) [19-910]
Interaction partners: - Conserved oligomeric Golgi complex subunit 4
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:0070887 (cellular response to chemical stimulus), GO:0010035 (response to inorganic substance), GO:0010038 (response to metal ion), GO:0071241 (cellular response to inorganic substance), GO:0032026 (response to magnesium ion), GO:0071248 (cellular response to metal ion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: superoxide dismutase (A0A2H1A2D9)
Organism: Candidozyma auris (Yeast) (Candida auris)
Subcellular location: Membrane; Lipid- anchor, GPI-anchor. Secreted, cell wall
Sequence: MIWKPFTFAALFSAAAVADPAPESHDSPTDVSYRATFTKGVDGYVNFSSKNGSVIVDVDISGLPNYGGPFMYHIHEKQVPSDGNCTGTKAHFNPYHGYEKAPTPAELEVGDLSGRHGEIHAQSFQTSYIDPYLSLNPDNKAFFANLSVVVHLHNTSRIACANITKEYTVPPVEGGASGKTLAAGAVALAAGALLI
InterPro domains: - IPR024134: Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone (family) [27-164]
- IPR036423: Superoxide dismutase-like, copper/zinc binding domain superfamily (homologous_superfamily) [26-169]
- IPR001424: Superoxide dismutase, copper/zinc binding domain (domain) [41-184]
Interaction partners: - Superoxide dismutase 1 copper chaperone
- Catalase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016209 (antioxidant activity), GO:0004784 (superoxide dismutase activity), GO:0043167 (ion binding), GO:0016491 (oxidoreductase activity), GO:0043169 (cation binding), GO:0016721 (oxidoreductase activity, acting on superoxide radicals as acceptor), GO:0046872 (metal ion binding), GO:0046914 (transition metal ion binding), GO:0005507 (copper ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0009607 (response to biotic stimulus), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0051707 (response to other organism), GO:0010035 (response to inorganic substance), GO:0043207 (response to external biotic stimulus), GO:0006979 (response to oxidative stress), GO:0072593 (reactive oxygen species metabolic process), GO:0098869 (cellular oxidant detoxification), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0075136 (response to host), GO:1901700 (response to oxygen-containing compound), GO:0034599 (cellular response to oxidative stress), GO:0052200 (response to host defenses), GO:0062197 (cellular response to chemical stress), GO:0006801 (superoxide metabolic process), GO:1901701 (cellular response to oxygen-containing compound), GO:0000302 (response to reactive oxygen species), GO:0000305 (response to oxygen radical), GO:0000303 (response to superoxide), GO:0052572 (response to host immune response), GO:0034614 (cellular response to reactive oxygen species), GO:0071450 (cellular response to oxygen radical), GO:0071451 (cellular response to superoxide)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)