Protein: Patched family protein (F4JTN1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004127}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004127}.
Sequence: MAIPTKLLLLQLFTFSLLLTANLTHSEPSNNRHSKEYCAMYDICGHRSDGKVLNCPYASPSIQPDELFSAKIQSLCPTISGNVCCTETQFDTLRSQVQQAVPFLVGCPACLRNFLNLFCELSCSPNQSLFINVTSVAEVSGNLTVDGIDYHITDTFGEGLYESCKEVKFGTMNTRAINFVGGGAKNFREWFTFIGQKAPSGFPGSPYAINFKSSIPESSAMVPMNVSVYSCGDTSLGCSCGDCPSSPACSSPEPLPPHDEDSCSIRIGPLKVRCIELSMALVYVLLVSCFFGWAGLNRRRNTTQPLDSSKPLLHPVEEDGINSEMKENILGVKVQRHAQLSPVQRYMAKFYRSYGSWIARNPSLVLFMSVAIVLALCSGLYNFKVETRPEKLWVGPESKAAEEKKFFDTHLSPFYRIEQLILATVPDPKSGRAPSIVTDENILLLFDIQQKVDQIRGNYSGSEVSLPDICLKPLGEDCATQSILQYFKMDSGTFDDYGGVEHAEYCFQHYTSSETCLSAFQAPVDPSAVLGGFSGNNYSEVMVSELGCSVPFDCYSDVKRTLFQATAFVVTYPVNNVIGDSSNENARAVAWEKSFIQLAKEELLPMVRSKNLSLSFSSESSIEEELKRESTADVITIAASYLVMFVYISVTLGDAPQFYTFYISSKVLLGLSGVVLVLLSVLGSVGVFSALGVKSTLIIMEVIPFLVLAVGVDNMCILVHAVKRQPREVSLEQRISSALVEVGPSITLASLSEVLAFAVGAFVPMPACRIFSMFAALAIMLDFFLQITAFVALIVFDCKRSADNRIDCFPCIKVPSSSRESVEGGREPGFLERYMKEVHAPVLGLWGVKMVVVAVFFAFALASIAISPRLETGLEQKIVLPRDSYLQDYFDSLSEYLRVGPPLYFVVKNYNYSSESRHTNQLCSISQCNSNSLLNEISRASQASDTSYIAKPAASWLDDFLVWLSPEAFGCCRKFTNGSYCPPDDQPPCCTAEEDICSLDGICKDCTTCFRHSDLVQDRPSTAQFREKLPWFLNALPSADCAKGGHGAYTNSVDLKGYESGVIQASEFRTYHTPLNTQGDYVNALRAAREFSSRISNSLKIDIFPYSVFYIFFEQYLNIWTVALTNLAIAIGAIFIVCWLITSSAWSSAIIVLVLVMILVDLMGMMVILGIQLNAVSVVNLIMSIGIAVEFCVHISHAFLMSSGDREHRAREALETMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSLAGPPQLNLDIEQQQTDEASSSLLN
InterPro domains: - IPR004765: NPC1-like (family) [38-1274]
- IPR053958: HMGCR/SNAP/NPC1-like, sterol-sensing domain (domain) [663-813]
- IPR032190: Niemann-Pick C1, N-terminal (domain) [36-265]
- IPR000731: Sterol-sensing domain (domain) [633-796]
- IPR053956: NPC1, middle luminal domain (domain) [404-619]
Interaction partners: - Transcription factor bHLH27
- Transcription factor bHLH35
- At5g17540
- Cytochrome P450 76C3
- Cytochrome P450 76C1
- Cytochrome P450 76C4
- Cytochrome P450 76C2
- Phosphomethylpyrimidine synthase, chloroplastic
- Cytochrome P450, family 76, subfamily C, polypeptide 5
- Cytochrome P450 monooxygenase-like protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:0008289 (lipid binding), GO:0005515 (protein binding), GO:0005496 (steroid binding), GO:0032934 (sterol binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0048229 (gametophyte development), GO:0080090 (regulation of primary metabolic process), GO:0044087 (regulation of cellular component biogenesis), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0046890 (regulation of lipid biosynthetic process), GO:0009555 (pollen development), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0019216 (regulation of lipid metabolic process), GO:0090153 (regulation of sphingolipid biosynthetic process), GO:1905038 (regulation of membrane lipid metabolic process), GO:0031326 (regulation of cellular biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031967 (organelle envelope), GO:0005783 (endoplasmic reticulum), GO:0005635 (nuclear envelope), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)