Protein: Activating transcription factor-2 (Q56H90)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MDTAGDMDHLASVSFGDFETKSPEGDVSCYQNFRAQAEHVSLDISLGQKSDTLFAADQTPTPTRLIKNCDEVGLFEDLQHVNPFDIGFQQAAERNVSGTPSRPEARPNDGESLHTPQVYPVEAPTVVSVPSENQVPQSVSCGDMDVDQLLATTVTSPSKASQDGPPPLQLIQPQVLTWVLPAQSVPISIATVDCNRNRVKPTGAIHPFILPKPTAKELNKTSKRPEPILVSCNPPNNEPSSASLTPTSQLPIKERLKAIIHSNNNRRSFSTPPKAAKAKDRSRDEDCMERRRAAASRYRNKMRNEHKDLIKQNAQLQQENQELHERISRLEKELQQHRSHSSLAGVVADQLRIPPSSIHLLINVPNVLVPSSASNASAAKK
InterPro domains: - IPR004827: Basic-leucine zipper domain (domain) [281-339]
- IPR051027: Basic leucine zipper (bZIP) transcription factors (family) [41-266]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0001216 (DNA-binding transcription activator activity), GO:0042802 (identical protein binding), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific), GO:0046983 (protein dimerization activity), GO:0042803 (protein homodimerization activity), GO:0003677 (DNA binding), GO:0001228 (DNA-binding transcription activator activity, RNA polymerase II-specific), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0002376 (immune system process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0009628 (response to abiotic stimulus), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0006955 (immune response), GO:0030431 (sleep), GO:0071840 (cellular component organization or biogenesis), GO:0009892 (negative regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0048522 (positive regulation of cellular process), GO:0009266 (response to temperature stimulus), GO:0035556 (intracellular signal transduction), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0006970 (response to osmotic stress), GO:0060255 (regulation of macromolecule metabolic process), GO:0002251 (organ or tissue specific immune response), GO:0009891 (positive regulation of biosynthetic process), GO:0009408 (response to heat), GO:0104004 (cellular response to environmental stimulus), GO:0031325 (positive regulation of cellular metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0071214 (cellular response to abiotic stimulus), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0016043 (cellular component organization), GO:0080090 (regulation of primary metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0062197 (cellular response to chemical stress), GO:0071470 (cellular response to osmotic stress), GO:0000165 (MAPK cascade), GO:0006325 (chromatin organization), GO:0009651 (response to salt stress), GO:0002385 (mucosal immune response), GO:0010468 (regulation of gene expression), GO:0046890 (regulation of lipid biosynthetic process), GO:0031098 (stress-activated protein kinase signaling cascade), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0090207 (regulation of triglyceride metabolic process), GO:0034605 (cellular response to heat), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0019216 (regulation of lipid metabolic process), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0010629 (negative regulation of gene expression), GO:0051403 (stress-activated MAPK cascade), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0040029 (epigenetic regulation of gene expression), GO:0006338 (chromatin remodeling), GO:0045814 (negative regulation of gene expression, epigenetic), GO:1902680 (positive regulation of RNA biosynthetic process), GO:0010866 (regulation of triglyceride biosynthetic process), GO:0006357 (regulation of transcription by RNA polymerase II), GO:0045893 (positive regulation of DNA-templated transcription), GO:0031507 (heterochromatin formation), GO:0070828 (heterochromatin organization), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045944 (positive regulation of transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098687 (chromosomal region), GO:0000785 (chromatin), GO:0000792 (heterochromatin), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000775 (chromosome, centromeric region), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005721 (pericentric heterochromatin), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome), GO:0010369 (chromocenter), GO:0005634 (nucleus)