Protein: Floral homeotic protein APETALA 3 (P35632)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor involved in the genetic control of flower development. Is required for normal development of petals and stamens in the wild-type flower. Forms a heterodimer with PISTILLATA that is required for autoregulation of both AP3 and PI genes. AP3/PI heterodimer interacts with APETALA1 or SEPALLATA3 to form a ternary complex that could be responsible for the regulation of the genes involved in the flower development. AP3/PI heterodimer activates the expression of NAP. AP3/PI prevents GATA22/GNL and GATA21/GNC expression.
Subcellular location: Nucleus.
Sequence: MARGKIQIKRIENQTNRQVTYSKRRNGLFKKAHELTVLCDARVSIIMFSSSNKLHEYISPNTTTKEIVDLYQTISDVDVWATQYERMQETKRKLLETNRNLRTQIKQRLGECLDELDIQELRRLEDEMENTFKLVRERKFKSLGNQIETTKKKNKSQQDIQKNLIHELELRAEDPHYGLVDNGGDYDSVLGYQIEGSRAYALRFHQNHHHYYPNHGLHAPSASDIITFHLLE
InterPro domains: - IPR033896: MADS MEF2-like, N-terminal (domain) [2-80]
- IPR002487: Transcription factor, K-box (domain) [81-174]
- IPR002100: Transcription factor, MADS-box (domain) [1-61]
- IPR036879: Transcription factor, MADS-box superfamily (homologous_superfamily) [3-107]
- IPR050142: MADS-box/MEF2 Transcription Factor (family) [3-157]
Interaction partners: - Protein LEAFY
- Developmental protein SEPALLATA 3
- Floral homeotic protein PISTILLATA
- Floral homeotic protein APETALA 2
- Protein TERMINAL FLOWER 1
- MADS-box protein
- Protein WUSCHEL
- AP-3 complex subunit mu
- Transcriptional corepressor SEUSS
- Protein SPOROCYTELESS
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0003006 (developmental process involved in reproduction), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0007389 (pattern specification process), GO:0009791 (post-embryonic development), GO:0090698 (post-embryonic plant morphogenesis), GO:0099402 (plant organ development), GO:0048608 (reproductive structure development), GO:0010093 (specification of floral organ identity), GO:0048437 (floral organ development), GO:1905393 (plant organ formation), GO:0048449 (floral organ formation), GO:1905392 (plant organ morphogenesis), GO:0003002 (regionalization), GO:0090567 (reproductive shoot system development), GO:0048731 (system development), GO:0048444 (floral organ morphogenesis), GO:0090696 (post-embryonic plant organ development), GO:0048367 (shoot system development), GO:0061458 (reproductive system development), GO:0090701 (specification of plant organ identity), GO:0009908 (flower development), GO:0090697 (post-embryonic plant organ morphogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)