wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Box C/D snoRNA protein 1 (Serologically defined breast cancer antigen NY-BR-75) (Zinc finger HIT domain-containing protein 6) (Q9NWK9)
Organism: Homo sapiens (Human)
Function: Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.
Sequence: MEFAAENEGKSGGGLHSVAEGVRLSPEPGREGVRDLAGAEEFGGGEEGTGLTGIKEIGDGEEGSGQRPEEIPMDLTVVKQEIIDWPGTEGRLAGQWVEQEVEDRPEVKDENAGVLEVKQETDSSLVVKEAKVGEPEVKEEKVKEEVMDWSEVKEEKDNLEIKQEEKFVGQCIKEELMHGECVKEEKDFLKKEIVDDTKVKEEPPINHPVGCKRKLAMSRCETCGTEEAKYRCPRCMRYSCSLPCVKKHKAELTCNGVRDKTAYISIQQFTEMNLLSDYRFLEDVARTADHISRDAFLKRPISNKYMYFMKNRARRQGINLKLLPNGFTKRKENSTFFDKKKQQFCWHVKLQFPQSQAEYIEKRVPDDKTINEILKPYIDPEKSDPVIRQRLKAYIRSQTGVQILMKIEYMQQNLVRYYELDPYKSLLDNLRNKVIIEYPTLHVVLKGSNNDMKVLHQVKSESTKNVGNEN
InterPro domains: - IPR051639: Box C/D snoRNA (family) [214-462]
- IPR057721: BCD1, alpha/beta domain (domain) [307-453]
- IPR007529: Zinc finger, HIT-type (domain) [218-254]
Interaction partners: - FMR1-interacting protein NUFIP1
- Nucleolar protein 58
- Zinc finger HIT domain-containing protein 3
- PIH1 domain-containing protein 1
- Nucleolar protein 56
- RuvB-like 1
- RuvB-like 2
- Transcription initiation factor TFIID subunit 9
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0006357 (regulation of transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: DNA-binding protein RFX2 (Regulatory factor X 2) (Q5EAP5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Transcription factor that acts as a key regulator of ciliogenesis. Specifically regulates expression of genes required for cilium assembly and function. Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:B2GV50, ECO:0000255|PROSITE-ProRule:PRU00858}. Cytoplasm {ECO:0000250|UniProtKB:B2GV50}. Note=Mainly expressed in the nucleus and at lower level in cytoplasm. {ECO:0000250|UniProtKB:B2GV50}.
Sequence: MQRSEGGSETPSTVALRTSTSAQAPVVQPVPASQQRVLVQATGSSQKGAQVQQLPVPRVQQVPQQVQQVQHYHSQQVQYVEGAEAVYPNGTIRAAYSYNPESQLYGQGSGSAYFDSQAGGAQVTTVVSSGGVPTHGMVGIAMDVGGSQIISSGSAYLIHGGMEGGRHHTSHSSRSSSAMLEMAIENLQKSEGIATHKSSLLNSHLQWLLDNYETAEGVSLPRSSLYNHYLRHCQEQKLDPVNAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGIRLKPDSPLNRMQEDTQYMAMRQTPVHQKQRFKPFHKMDGMGDSLNSGSQHLSSTPEQSVAAQCQHHQQYIDVSHVLPPFPSLDLGSCPLPESISMTDVKKLQSSYRIHCEATLDVVMNLQFHLIEKLWQTFWHSTAPSSDGATTIPNSEEDVEDIRGFPRDKLITLCKYEPIKQWMRSCDHILYQALVEILIPDVLRPVPSTLTQAIRNFAKSLEGWLTSAMTNFPPEIISTKAAVVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASWVCQCDESVVQRLELDFKATLQQQSSLDQWAAWLDNVVNQVLKPYDGSLSFPRAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGEFSDLSSLMPSLKEQDTSFSDDMTSDGDMSRMSERSLTEPAVKRERIEIPHSLQEI
InterPro domains: - IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [205-278]
- IPR057321: RFX1-4/6/8-like, BCD domain (domain) [376-667]
- IPR039779: RFX-like DNA-binding protein (family) [65-709]
- IPR003150: DNA-binding RFX-type winged-helix domain (domain) [204-279]
- IPR007668: RFX1 transcription activation region (domain) [4-159]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [204-278]
Interaction partners: - Forkhead box protein J1-A
- Multicilin
- ATR serine/threonine kinase
- Intraflagellar transport 88 homolog.
- Highly divergent homeobox
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0048856 (anatomical structure development), GO:0009653 (anatomical structure morphogenesis), GO:0009888 (tissue development), GO:0048729 (tissue morphogenesis), GO:0007498 (mesoderm development), GO:0048332 (mesoderm morphogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: ATP synthase subunit a (Q37807)
Organism: Oryza sativa (Rice)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion inner membrane {ECO:0000256|RuleBase:RU004450}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU004450}.
Sequence: MNFDHNHVVIMGLNQRDSIWKLLNDYNVNSLKRRRQAEIDAFFEPFERAQRIRFNNWQNGIELLDGAEWRNGDIVIPGGGGPVISSPLDQFFIDPLFGLDMGNFYLSFTNESLSMAVTVVLVPSLFGVVTKKGGGKSVPNAWQSLVELIYDFVLNLVNEQIGGNVKQKFFPRISVTFTFSLFRNPQGMIPFSFTVTSHFLITLALSFSIFIGITIVGFQRHGLHFFSFLLPAGVPLPLAPFLVLLELISHCFRALSSGIRLFANMMAGHSSVKILSGFAWTMLFLNNIFYFIGDLGPLFIVLALTGLELGVAILQAHVSTISICIYLNDAINLHQNE
InterPro domains: - IPR000568: ATP synthase, F0 complex, subunit A (family) [89-334]
- IPR045083: ATP synthase, F0 complex, subunit A, bacterial/mitochondria (family) [80-334]
- IPR023011: ATP synthase, F0 complex, subunit A, active site (active_site) [256-265]
- IPR035908: ATP synthase, F0 complex, subunit A superfamily (homologous_superfamily) [164-334]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0009266 (response to temperature stimulus), GO:0009409 (response to cold)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Geraniol synthase, chloroplastic (ObGES) (EC 3.1.7.11) (Q6USK1)
Organism: Ocimum basilicum (Sweet basil)
Function: Monoterpene synthase that catalyzes the formation of geraniol from geranyl diphosphate.
Subcellular location: Plastid, chloroplast {ECO:0000255}.
Sequence: MSCARITVTLPYRSAKTSIQRGITHYPALIRPRFSACTPLASAMPLSSTPLINGDNSQRKNTRQHMEESSSKRREYLLEETTRKLQRNDTESVEKLKLIDNIQQLGIGYYFEDAINAVLRSPFSTGEEDLFTAALRFRLLRHNGIEISPEIFLKFKDERGKFDESDTLGLLSLYEASNLGVAGEEILEEAMEFAEARLRRSLSEPAAPLHGEVAQALDVPRHLRMARLEARRFIEQYGKQSDHDGDLLELAILDYNQVQAQHQSELTEIIRWWKELGLVDKLSFGRDRPLECFLWTVGLLPEPKYSSVRIELAKAISILLVIDDIFDTYGEMDDLILFTDAIRRWDLEAMEGLPEYMKICYMALYNTTNEVCYKVLRDTGRIVLLNLKSTWIDMIEGFMEEAKWFNGGSAPKLEEYIENGVSTAGAYMAFAHIFFLIGEGVTHQNSQLFTQKPYPKVFSAAGRILRLWDDLGTAKEEQERGDLASCVQLFMKEKSLTEEEARSRILEEIKGLWRDLNGELVYNKNLPLSIIKVALNMARASQVVYKHDQDTYFSSVDNYVDALFFTQ
InterPro domains: - IPR008930: Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid (homologous_superfamily) [60-243]
- IPR005630: Terpene synthase, metal-binding domain (domain) [274-515]
- IPR001906: Terpene synthase, N-terminal domain (domain) [60-217]
- IPR008949: Isoprenoid synthase domain superfamily (homologous_superfamily) [58-564]
- IPR034741: Terpene cyclase-like 1, C-terminal domain (domain) [246-555]
- IPR050148: Terpene synthase-like (family) [69-551]
- IPR044814: Terpene cyclases, class 1, plant (family) [90-565]
- IPR036965: Terpene synthase, N-terminal domain superfamily (homologous_superfamily) [90-243]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016835 (carbon-oxygen lyase activity), GO:0016838 (carbon-oxygen lyase activity, acting on phosphates), GO:0010333 (terpene synthase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0120252 (hydrocarbon metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0006720 (isoprenoid metabolic process), GO:0042214 (terpene metabolic process), GO:0120251 (hydrocarbon biosynthetic process), GO:0008299 (isoprenoid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0043692 (monoterpene metabolic process), GO:0046246 (terpene biosynthetic process), GO:0043693 (monoterpene biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: GATA zinc finger domain-containing protein 1 (Q1L8G7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Component of some chromatin complex recruited to chromatin sites methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q8WUU5}.
Sequence: MPLGLKPCCAVCKTQSSSMWKKGNQGEILCNGCTGKAVSSGGSGASASSTIQQNNGGGKQSKQEIHRRSARLRSTKYKAPASEKKVSTKGKGRRHIFKLKNPIKAPESVSTIITSESMFYKGIYYQIGDVIKVIDEDDGKPYYAQIRGFVQDQYCEKSAALTWLIPTQASPRDRFDPSTYIVGPEEDLPRKMEYLEFVCHAPSEYFKSRSCPFPTLPVRPEKGYVWTHIGPTPAVAIKETVG
InterPro domains: - IPR000679: Zinc finger, GATA-type (domain) [9-33]
- IPR039050: GATA zinc finger domain-containing protein 1 (family) [1-241]
Interaction partners: - PHD finger protein 12
- PHD finger protein 12
- Mortality factor 4-like protein 1
- Transmembrane protein 101
- BRCA2-interacting transcriptional repressor EMSY
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0072001 (renal system development), GO:0001822 (kidney development), GO:0048793 (pronephros development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Probable WRKY transcription factor 65 (WRKY DNA-binding protein 65) (Q9LP56)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00223}.
Sequence: MKRGLDMARSYNDHESSQETGPESPNSSTFNGMKALISSHSPKRSRRSVEKRVVNVPMKEMEGSRHKGDTTPPSDSWAWRKYGQKPIKGSPYPRGYYRCSSTKGCPARKQVERSRDDPTMILITYTSEHNHPWPLTSSTRNGPKPKPEPKPEPEPEVEPEAEEEDNKFMVLGRGIETTPSCVDEFAWFTEMETTSSTILESPIFSSEKKTAVSGADDVAVFFPMGEEDESLFADLGELPECSVVFRHRSSVVGSQVEIF
InterPro domains: - IPR044810: WRKY transcription factor, plant (family) [11-242]
- IPR003657: WRKY domain (domain) [68-134]
- IPR036576: WRKY domain superfamily (homologous_superfamily) [60-135]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0006950 (response to stress), GO:0090693 (plant organ senescence), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006952 (defense response), GO:0099402 (plant organ development), GO:0043207 (response to external biotic stimulus), GO:0010150 (leaf senescence), GO:0009620 (response to fungus), GO:0048731 (system development), GO:0098542 (defense response to other organism), GO:0048367 (shoot system development), GO:0048827 (phyllome development), GO:0050832 (defense response to fungus), GO:0048366 (leaf development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Protein kinase A regulatory subunit (Q385V6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MSEKGTSLNLFLAACQKEGVKQPNTFLVEFFTKKPELSEVEEIDLSKNYIGNRGILALLDVISELPCFRFLNCSNQKLYNTDLNEDSVRGNATIDRIVDVFKSHPTANALDLSHNPISNYAGRRLLLLTQNNKRICRVELVDTRIDFELRSRITQQCEKNTIAIWESQAQEKEEERAFGESVTWVPTQTSADLTAIGGGRKRRTTVRGEGIDPEKAKSYVAPYFEKSEDETALILKLLTYNVLFSFLDSRDLMTVAGAMWRVEFKQDDCIMEAGQTTCDKLYIIQDGKADIIKEGQKVYLKVEGTAVGELELMYQTPTVATVKVCTPELIAWALDRDTYRHLVMGSAIRRRETYIQFLTNIPFLSGLDNYEKLQLADALSSDEFEPGDYIIRYGEEGEWLYIILEGSVDVVGRDDDGNEKHVWEFGKGDHVGELEFLNNHANVADVVAKTHVVTAKLNRRHFEMCLGPVIDVLKRTSQQPNYEYYQSKLKTTLRAEGRK
InterPro domains: - IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [14-169]
- IPR050503: cAMP-dependent protein kinase regulatory subunit-like (family) [162-483]
- IPR014710: RmlC-like jelly roll fold (homologous_superfamily) [212-485]
- IPR000595: Cyclic nucleotide-binding domain (domain) [243-483]
- IPR018488: Cyclic nucleotide-binding, conserved site (conserved_site) [390-406]
- IPR018490: Cyclic nucleotide-binding domain superfamily (homologous_superfamily) [222-470]
Interaction partners: - Protein kinase A catalytic subunit isoform 2
- Protein kinase A catalytic subunit isoform 1
- Protein kinase A catalytic subunit
- non-specific serine/threonine protein kinase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0007267 (cell-cell signaling), GO:0048870 (cell motility), GO:0051606 (detection of stimulus), GO:0007017 (microtubule-based process), GO:0009607 (response to biotic stimulus), GO:0044145 (modulation of formation of structure involved in a symbiotic process), GO:0007154 (cell communication), GO:0001539 (cilium or flagellum-dependent cell motility), GO:0007018 (microtubule-based movement), GO:0009595 (detection of biotic stimulus), GO:0009372 (quorum sensing), GO:0060245 (detection of cell density), GO:0003341 (cilium movement), GO:0060285 (cilium-dependent cell motility), GO:0060294 (cilium movement involved in cell motility)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0042995 (cell projection), GO:1902494 (catalytic complex), GO:0140535 (intracellular protein-containing complex), GO:0099080 (supramolecular complex), GO:1990234 (transferase complex), GO:0120025 (plasma membrane bounded cell projection), GO:0005952 (cAMP-dependent protein kinase complex), GO:0097740 (paraflagellar rod), GO:0043227 (membrane-bounded organelle), GO:0005929 (cilium), GO:0061695 (transferase complex, transferring phosphorus-containing groups), GO:0031514 (motile cilium), GO:1902911 (protein kinase complex), GO:0097729 (9+2 motile cilium), GO:1902554 (serine/threonine protein kinase complex)
Protein: Thermosome, alpha subunit (Q3AF10)
Organism: Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901)
Function: Not known
Sequence: MKKENQTQEIEERYQALFSNAAAVKALTQVVANSLGPKGLDAMLVDRFGEVVVTNDGVTILTLMDAQHPAARMVVNMARAQEREVGDGTTTAAVLAGALVSEGVNQILKGVPVSKVLAGMNRALNHALFLIRKNAIKVGSITDDRLLAAAKIAGRGDERVAAILRDAAAMLEDKLQDPGFKLADLVLAKVGADTTLIPGVVINKSPLWEEGSQKLQEVRLLVLDDGLYPEEVEEEALASEAGFEQYLKNQKIFQENLKKLKELGVKLILLTRGISDIAEEFCYENEIMVITRITQKELKRVLEFTGARAAKRTSLNKPVEELQKMLGYARTCFYDSRLDFTIIEGGAGKATATVLIGAATDEVVDEQERIAKDAAGSFAAAYRSGVLPGGGAFFLYLSREVESLKNRLPGMESYGVMAFSEALKVPFRVMAENAGFNGLEKLGDLMTLQVQKNNYALGLDFETGEFIDMIAGGVVDPAEVVYQAVKNASEVAISLLKINTIIKMKDYEVLKEGEQEDGGKR
InterPro domains: - IPR027410: TCP-1-like chaperonin intermediate domain superfamily (homologous_superfamily) [138-384]
- IPR027409: GroEL-like apical domain superfamily (homologous_superfamily) [193-356]
- IPR002423: Chaperonin Cpn60/GroEL/TCP-1 family (family) [27-505]
- IPR002194: Chaperonin TCP-1, conserved site (conserved_site) [81-89]
- IPR027413: GroEL-like equatorial domain superfamily (homologous_superfamily) [5-504]
- IPR017998: Chaperone tailless complex polypeptide 1 (TCP-1) (family) [11-503]
Interaction partners: - Chaperone protein DnaK
- Protein GrpE
- Co-chaperonin GroES
- Heat-inducible transcription repressor HrcA
- Chaperone protein DnaJ
- Flagellar motor switch protein
- Inosine-5'-monophosphate dehydrogenase
- Negative regulator of genetic competence clpC/mecB
- Bifunctional NAD
- ATP-dependent protease ATPase subunit HslU
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0044403 (biological process involved in symbiotic interaction), GO:0009408 (response to heat), GO:0006970 (response to osmotic stress), GO:0051701 (biological process involved in interaction with host), GO:0009991 (response to extracellular stimulus), GO:0009266 (response to temperature stimulus), GO:0009268 (response to pH), GO:0042594 (response to starvation), GO:0009651 (response to salt stress), GO:0044406 (adhesion of symbiont to host), GO:0010447 (response to acidic pH), GO:0031667 (response to nutrient levels), GO:0006972 (hyperosmotic response), GO:0044650 (adhesion of symbiont to host cell), GO:0042538 (hyperosmotic salinity response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0009986 (cell surface), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030312 (external encapsulating structure), GO:0005618 (cell wall), GO:0005886 (plasma membrane), GO:0009274 (peptidoglycan-based cell wall)