Protein: Epimerase family protein SDR39U1 homolog, chloroplastic (EC 1.1.1.-) (Protein GIANT CHLOROPLAST 1) (Protein SulA homolog) (AtSulA) (Q9SJU9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Putative NADP-dependent oxidoreductase that acts as positive regulator of chloroplast division. May play a role at an early stage of the division process.
Subcellular location: Plastid, chloroplast inner membrane; Peripheral membrane protein; Stromal side {ECO:0000269|PubMed:15120068}. Plastid, chloroplast {ECO:0000269|PubMed:15208387}.
Sequence: MELLCSPTSLSSSFALSSALLVPRSFSMPGTRRFMVLCSSQKESQMTVSVTGATGFIGRRLVQRLRADNHAIRVLTRSKSKAEQIFPAKDFPGIVIAEESEWKNCVQGSTAVVNLAGLPISTRWSPEIKKEIKGSRIRVTSKVVDLINNSPAEARPTVLVSATAVGYYGTSETGVFDENSPSGKDYLAEVCREWEGTALKANKDVRVALIRIGVVLGKDGGALAMMIPFFQMFAGGPLGSGQQWFSWIHVDDLVNLIYEALTNPSYKGVINGTAPNPVRLGEMCQQLGSVLSRPSWLPVPDFALKALLGEGATVVLEGQKVLPVRAKELGFEFKYKYVKDALRAIMQ
InterPro domains: - IPR010099: Epimerase family protein SDR39U1 (family) [48-342]
- IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [42-345]
- IPR001509: NAD-dependent epimerase/dehydratase (domain) [49-265]
- IPR013549: Domain of unknown function DUF1731 (domain) [299-345]
Interaction partners: - Golgin candidate 1
- Cell division protein FtsZ homolog 2-1, chloroplastic
- Cell division protein FtsZ homolog 1, chloroplastic
- Protein CLMP1
- Probable histone H2A.2
- Protein C2-DOMAIN ABA-RELATED 8
- Acid phosphatase/vanadium-dependent haloperoxidase-related protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0016491 (oxidoreductase activity), GO:0003676 (nucleic acid binding), GO:0016627 (oxidoreductase activity, acting on the CH-CH group of donors), GO:0003723 (RNA binding), GO:0016628 (oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0042440 (pigment metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0046148 (pigment biosynthetic process), GO:0016117 (carotenoid biosynthetic process), GO:0006720 (isoprenoid metabolic process), GO:0008299 (isoprenoid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0006721 (terpenoid metabolic process), GO:0016114 (terpenoid biosynthetic process), GO:0016108 (tetraterpenoid metabolic process), GO:0016109 (tetraterpenoid biosynthetic process), GO:0016116 (carotenoid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009532 (plastid stroma), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0010287 (plastoglobule), GO:0005737 (cytoplasm), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009570 (chloroplast stroma), GO:0043228 (non-membrane-bounded organelle), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle), GO:0031976 (plastid thylakoid), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0009534 (chloroplast thylakoid), GO:0009579 (thylakoid)