Protein: ATP-dependent RNA helicase (EC 3.6.4.13) (Q389Z8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MSLKKKTLKQRLRKNEMRQRQKVSKDVRKRVRTGRRQCNRFDDIESGSRPLQELVEEIAAGSAAPTREVALDPRSLTDLLLQTSASLSNTNSGGKTAAKPNVGRGNSESDGKPRLVLPEAPLPEDHPLALPEVQLGEDELGGGKDTNSVPGGKNQYRHHGDPYVFWERVGLHPLLLKALRTMRFTHPTPVQEEVLPSVLSQNVDGRAVGGKEKITPGKGKSGGRGWEKDVIISAETGSGKTLAFAIPILQHVLTNVLVNEVTQGPDGKIGNEETANAAKGKEGKGKKTKGGGKSTERGKSESFKKSRKRLREGEEEGEQLTTAPPTTTFKLQGRLMQALIVSPTRELALQISEAMQQLVQHAPQVIVGCVVGGMAPEKQQRVLNRHPHVLICTPGRLWELMQKNEGCYLGHSLSRRLSYVVLDEADKLLQSGRFEELKNLLERIHCEILPAGYVQEREEGAEAGDAELEAGFWDAEKQKFVPFPKDSPTGDDDKKETPQLRTSRKDEPRLIPMPPDPPEGHRVTTFVTSATLSLQTNYVRRDMRAKKTVIRTSNEDTMGKVLQQLEIKPSNAHVFTISPKVDVAAKIHETYLRCPGDSKDLYLYYFLKMYRERSIVFVNAISMLRRLVKLLEVLGIPVAGLHASLQQRQRLKFIDKFRKGEKRVLVATDIASRGLDVEGVRYVVHFQVPRSTDAYIHRCGRTARCGGTGLSLLMVNAQEHVSFTKLMGSLGRSTGDLEVFALQPTIVHQLHAHLKVALQIDKLQKEIDKSRANNNWARRMSREADVDVDDLIDDDADTENKAKEKAIKILRRRLMLLGEKDMGTSGGKGSFRSSAQAIGAKQAESKLVERAQLQVTQKPKKGSKVVKKAGARKNTEKE
InterPro domains: - IPR000629: ATP-dependent RNA helicase DEAD-box, conserved site (conserved_site) [421-429]
- IPR014014: RNA helicase, DEAD-box type, Q motif (domain) [164-192]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [144-819]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [183-568]
- IPR011545: DEAD/DEAH-box helicase domain (domain) [227-445]
- IPR001650: Helicase, C-terminal domain-like (domain) [602-748]
Interaction partners: - RNA-binding protein, putative
- Ribosome biogenesis protein NSA1
- Nucleolar protein, putative
- NLE domain-containing protein
- ATP-dependent DEAD/H RNA helicase, putative
- Nop14-like protein
- RNA helicase
- rRNA biogenesis protein, putative
- Pumilio/PUF RNA binding protein 8, putative
- Ribosome biogenesis protein BOP1 homolog
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0043168 (anion binding), GO:0042301 (phosphate ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0042254 (ribosome biogenesis), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0034470 (ncRNA processing), GO:0006364 (rRNA processing), GO:0034660 (ncRNA metabolic process), GO:0016072 (rRNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)