Protein: Phosphoacetylglucosamine mutase (PAGM) (EC 5.4.2.3) (Acetylglucosamine phosphomutase) (N-acetylglucosamine-phosphate mutase) (Q57XH7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MVLQAAVADAICAAVAKYPLLHDARVDPMPYGTSGFRTIGTLLPPVASRVVYVAVLRVWWAIKKGNFGGLNGCSVGCMVTASHNPCGDNGLKLIDVDGGMLETSWETTCTQAANASTGEELLKVLNDCINLHGLEQPKPEDVKIRCPFGAVHLSRDTRPTGVDILSAIFSSLQAIGVTYADHGVLTTPQLHYLVGRANREQLTGPGAMKPADFTSALYAKEVFGSLGELLRFVTEGNGGTNPRQRQKIVIDAASGVGAVALKSLLKCAQEVTSGVFEEFFDVTVLHDNVDDINALNYMCGADYTQKAQYPSNDTKEWAAAYEKRRSDKNEEVHYYSLDGDADRVVAFFHDRETGEDVWRLLDGDRISILYALSVREWIGGEALKLLDVGVVQTAYANGASTDYIQRGLGLRTYSSQTGVKNLHPIAHKCDIGAYFESNGHGTILLNGDAIDAKVPSLPSKTRHVLSLLPRLISQVCGDAIANVFACELILLAHKMSFDSWLRLYTDIPSTQLKVKVKNPKVITNTQDERRALTPPGLQEAIDAAVAAANEATPSSATVARAFARPSGTEPIVRVYAEAATHAVSSKLANDVEEIVRRFCGGA
InterPro domains: - IPR049022: Phosphoacetylglucosamine mutase AMG1, domain III (domain) [362-493]
- IPR016657: Phosphoacetylglucosamine mutase (family) [6-602]
- IPR016055: Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III (homologous_superfamily) [21-129]
- IPR005843: Alpha-D-phosphohexomutase, C-terminal (domain) [539-593]
- IPR036900: Alpha-D-phosphohexomutase, C-terminal domain superfamily (homologous_superfamily) [496-600]
- IPR005844: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (domain) [72-114]
Interaction partners: - Glucosamine 6-phosphate N-acetyltransferase
- UDP-N-acetylglucosamine diphosphorylase
- mannose-1-phosphate guanylyltransferase
- GDP-mannose 4,6-dehydratase
- UDP-glucose 4-epimerase
- glucose-6-phosphate 1-epimerase
- riboflavin kinase
- GDP-L-fucose synthase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016853 (isomerase activity), GO:0016866 (intramolecular transferase activity), GO:0016868 (intramolecular transferase activity, phosphotransferases)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0009058 (biosynthetic process), GO:0071704 (organic substance metabolic process), GO:0071554 (cell wall organization or biogenesis), GO:0006807 (nitrogen compound metabolic process), GO:0071852 (fungal-type cell wall organization or biogenesis), GO:0044085 (cellular component biogenesis), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006037 (cell wall chitin metabolic process), GO:0042546 (cell wall biogenesis), GO:0043170 (macromolecule metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0009059 (macromolecule biosynthetic process), GO:0006038 (cell wall chitin biosynthetic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0006040 (amino sugar metabolic process), GO:0009272 (fungal-type cell wall biogenesis), GO:0006022 (aminoglycan metabolic process), GO:0006030 (chitin metabolic process), GO:0046349 (amino sugar biosynthetic process), GO:1901071 (glucosamine-containing compound metabolic process), GO:0006023 (aminoglycan biosynthetic process), GO:0006031 (chitin biosynthetic process), GO:1901073 (glucosamine-containing compound biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)