wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Pectate lyase A (EC 4.2.2.2) (Q5AVN4)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester.
Subcellular location: Secreted {ECO:0000305}.
Sequence: MQNLKFLIAAVSCLGPALAAPTPTSNFINSNFNKRASVEDSAFGYASLNGGTTGGAGGTTTTVSSYAEFTAAVQGDDPKIVIVSGPIEETAEQVDVGSNTSILGADSSAVLTGFGLRLKEVENVIIRNLGIAKVLADNGDAIGAEYSNNIWIDHVDVSSDRDHDKDYYDGLLDFKRGSDYITVSNSFIHDHWKASLVGHSNSNEDEDSGKLHVTYANNYWYNLNSRAPSIRFGTGHIYNNYYETVSDGINTRIGAQVLVEGNVFVDSKKALYSTDEGYAVERNNDFGDAKNEALEGTLTSVEYEYDLLDTSEVKSAVVGTAGQTLTF
InterPro domains: - IPR045032: Pectin lyase family (family) [33-270]
- IPR011050: Pectin lyase fold/virulence factor (homologous_superfamily) [40-325]
- IPR012334: Pectin lyase fold (homologous_superfamily) [34-325]
- IPR002022: Pectate lyase (domain) [56-270]
Interaction partners: - Pectinesterase A
- Probable endopolygalacturonase D
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016835 (carbon-oxygen lyase activity), GO:0016837 (carbon-oxygen lyase activity, acting on polysaccharides)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:1901575 (organic substance catabolic process), GO:0043170 (macromolecule metabolic process), GO:0005975 (carbohydrate metabolic process), GO:0016052 (carbohydrate catabolic process), GO:0009057 (macromolecule catabolic process), GO:0005976 (polysaccharide metabolic process), GO:0010393 (galacturonan metabolic process), GO:0000272 (polysaccharide catabolic process), GO:0045488 (pectin metabolic process), GO:0045490 (pectin catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Enoyl-[acyl-carrier-protein] reductase [NADH] (ENR) (EC 1.3.1.9) (Q8Z9U1)
Organism: Yersinia pestis
Function: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
Sequence: MIIKPRVRGFICVTAHPTGCEANVKKQIDYVTTEGPIANGPKRVLVIGASTGYGLAARITAAFGCGADTLGVFFERPGEEGKPGTSGWYNSAAFHKFAAQKGLYAKSINGDAFSDEIKQLTIDAIKQDLGQVDQVIYSLASPRRTHPKTGEVFNSALKPIGNAVNLRGLDTDKEVIKESVLQPATQSEIDSTVAVMGGEDWQMWIDALLDAGVLAEGAQTTAFTYLGEKITHDIYWNGSIGAAKKDLDQKVLAIRESLAAHGGGDARVSVLKAVVTQASSAIPMMPLYLSLLFKVMKEKGTHEGCIEQVYSLYKDSLCGDSPHMDQEGRLRADYKELDPEVQNQVQQLWDQVTNDNIYQLTDFVGYKSEFLNLFGFGIDGVDYDADVNPDVKIPNLIQG
InterPro domains: - IPR024906: Enoyl reductase FAD binding domain (domain) [324-387]
- IPR050048: Trans-2-enoyl-CoA reductase-like, NAD(P)H binding domain (domain) [2-79]
- IPR010758: Trans-2-enoyl-CoA reductase (family) [1-398]
- IPR024910: Trans-2-enoyl-CoA reductase catalytic domain, putative (domain) [82-317]
Interaction partners: - 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
- 3-oxoacyl-[acyl-carrier-protein] synthase II
- 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ
- Similar to Escherichia coli 3-oxoacyl-[acyl-carrier-protein] synthase I FabB SW:FABB_ECOLI
- Fatty acid oxidation complex subunit alpha
- Fatty acid oxidation complex subunit alpha
- Acyl-coenzyme A dehydrogenase
- Similar to Escherichia coli aldehyde-alcohol dehydrogenase AdhE SW:ADHE_ECOLI
- Irp1 protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0016740 (transferase activity), GO:0097159 (organic cyclic compound binding), GO:0016491 (oxidoreductase activity), GO:1901265 (nucleoside phosphate binding), GO:0016627 (oxidoreductase activity, acting on the CH-CH group of donors), GO:0000166 (nucleotide binding), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016628 (oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor), GO:0017076 (purine nucleotide binding), GO:0004312 (fatty acid synthase activity), GO:0030554 (adenyl nucleotide binding), GO:0051287 (NAD binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:0070887 (cellular response to chemical stimulus), GO:0010035 (response to inorganic substance), GO:0010038 (response to metal ion), GO:0071241 (cellular response to inorganic substance), GO:0071248 (cellular response to metal ion), GO:0010039 (response to iron ion), GO:0071281 (cellular response to iron ion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: glutaminase (EC 3.5.1.2) (Q66V97)
Organism: Aspergillus oryzae (Yellow koji mold)
Function: Not known
Sequence: MKSPIPDYLRQVLEKARPDDSGQLANYIDVLAKADPSKMAIALSTVDGNLYSAGDDEVEFSIQSISKAFVYAIAIEDAGLPRVLEKIGVEPSGDAFNKLSLQPGTNRPMNPMINAGAIAAHTLVAGESASAEERVDHILKVLSKLAGRQLKVDEEVYEAELKDANRNMAIGYMLKAAGIISCDPQDAVRGYIRQGSITTNVRDLAMMAATLANAGVNPITGEEIMPHQSARQVLSVMTTCGMYDAAGDWVSRVGMPAKSGVAGGIIGALPGQVGIAVFSPKLDERGNSFRGVKMFEQLSSEMGLHMMDISQVGRATVRTWTLTIAGGAKQPDEREQEVPVFGLRGAVRFAGSERLTRAIVRELTPPNPDDPGSGRHADASAVIFSLKDTYSLNYVALRIISEDMRRLLAADKNVVVIDPVKVLKIDGNPAFKEKSPCVVNDEAEARRYIGGQGCRAVSHSDEFY
InterPro domains: - IPR012338: Beta-lactamase/transpeptidase-like (homologous_superfamily) [2-309]
- IPR036513: STAS domain superfamily (homologous_superfamily) [327-429]
- IPR015868: Glutaminase (family) [5-318]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0016811 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009056 (catabolic process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:1901575 (organic substance catabolic process), GO:0044248 (cellular catabolic process), GO:0043603 (amide metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006518 (peptide metabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0043171 (peptide catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Decorin-binding protein A (O50917)
Organism: Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) (Borrelia burgdorferi)
Function: Binds to decorin which may mediate the adherence of B.burgdorferi to collagen fibers in skin and other tissues.
Sequence: MIKCNNKTFNNLLKLTILVNLLISCGLTGATKIRLERSAKDITDEIDAIKKDAALKGVNFDAFKDKKTGSGVSENPFILEAKVRATTVAEKFVIAIEEEATKLKETGSSGEFSAMYDLMFEVSKPLQKLGIQEMTKTVSDAAEENPPTTAQGVLEIAKKMREKLQRVHTKNYCTLKKKENSTFTDEKCKNN
InterPro domains: - IPR003332: Decorin-binding protein (family) [32-171]
- IPR054923: Decorin-binding protein A (family) [1-170]
- IPR038353: Decorin-binding superfamily (homologous_superfamily) [26-191]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0044403 (biological process involved in symbiotic interaction), GO:0051701 (biological process involved in interaction with host), GO:0044000 (movement in host), GO:0044409 (entry into host)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)
Protein: Seed lectin alpha chain (P86352)
Organism: Spatholobus parviflorus (Butea parviflora)
Function: Galactose-binding lectin. Exhibits hemagglutination activity in a calcium- and magnesium-dependent manner. Also binds to several carbohydrates including lactose, D-galactose and GalNAc in a calcium- and magnesium-dependent manner. Likely to have antifungal activity as it is able to inhibit the activity of the A.flavus alpha-amylase.
Sequence: AEETSFVFSKFKPLEPNLILQGDALVTVAGVLQLTNVDKNGVPEPSSLGRATYSAPINIWDSATGLVASFATSFRFTIYAPNIATIADGLAFFLAPVASAPDSGGGFLGLFDSAVSGSTYQTVAVEFDTYENTVFTDPPYTHIGFDVNSISSIKTVKWSLANGEAAKVLITYNSAVKLLVASLVYPSSKTSFILADIVDLSSVLPEWVRVGFSAATGASGGKIETHDVFSWSFASKLAGXXTKDSSFLDGG
InterPro domains: - IPR019825: Legume lectin, beta chain, Mn/Ca-binding site (binding_site) [123-129]
- IPR050258: Leguminous Lectin (family) [3-238]
- IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [2-239]
- IPR001220: Legume lectin domain (domain) [4-238]
- IPR016363: Legume lectin (family) [1-244]
- IPR000985: Legume lectin, alpha chain, conserved site (conserved_site) [204-213]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030234 (enzyme regulator activity), GO:0036094 (small molecule binding), GO:0030246 (carbohydrate binding), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0140678 (molecular function inhibitor activity), GO:0070492 (oligosaccharide binding), GO:0048029 (monosaccharide binding), GO:0043169 (cation binding), GO:0004857 (enzyme inhibitor activity), GO:0048030 (disaccharide binding), GO:0005534 (galactose binding), GO:0046872 (metal ion binding), GO:0046914 (transition metal ion binding), GO:0005509 (calcium ion binding), GO:0030145 (manganese ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0009987 (cellular process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023057 (negative regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0007155 (cell adhesion), GO:0048585 (negative regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0098609 (cell-cell adhesion), GO:0010646 (regulation of cell communication), GO:0009966 (regulation of signal transduction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0005773 (vacuole), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000325 (plant-type vacuole), GO:0043231 (intracellular membrane-bounded organelle)
Protein: TRPL translocation defect 14, isoform C (A8DYI2)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MATLLSNGQQSVMASTSNGQEQQRHQDEPEQQQQVEIRKSSSPKPGAMPSLKLNRMGSVSPKDKRVYKIVLTGGPCGGKTTGQSRLCTFFENLGWKVFRVPETATVLLSGGVKFSDLTEKEDPPTPTTFVYKDLPFAAPEHSLIDLTASCPRCLAKAASRPNGSEAYKFQENLIRTMVQIENTYFELGNSSNRNCLIICDRGVMDASAYISKDKWEKMMAGNNWNPVEMRDNRYNQILHLVSAANGAEDFYSTEDHACRSEGVDLARELDYKSAAAWVGHPYFDVIDNSTNFETKMNRMIESVCQKLGIDIGDRLQATSRKLKYLVALLPPDSEFPPFQDFDVVHHYLQSAGPKVQARLRKRGQKNHWSYIHTQRRPNVHGQARIEVKTQLTHRDYMNLLAQRDDAHFTIYKKRRCFLINNQYFQLDIYKEPGHPRCKGLVLLETYSSLTGDALKNCMPKFLNIVKEVTGDPDYSMFNLSLKEDWSTTKKFCRSATHVKGAANGVSSTPLLLNGQ
InterPro domains: - IPR053227: TRPL channel trafficking regulator (family) [52-485]
- IPR033469: CYTH-like domain superfamily (homologous_superfamily) [329-481]
- IPR038727: NadR/Ttd14, AAA domain (domain) [188-294]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0008289 (lipid binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0097367 (carbohydrate derivative binding), GO:0005543 (phospholipid binding), GO:1901265 (nucleoside phosphate binding), GO:0043168 (anion binding), GO:0000166 (nucleotide binding), GO:0032553 (ribonucleotide binding), GO:0035639 (purine ribonucleoside triphosphate binding), GO:0035091 (phosphatidylinositol binding), GO:0070300 (phosphatidic acid binding), GO:0032555 (purine ribonucleotide binding), GO:0017076 (purine nucleotide binding), GO:0005525 (GTP binding), GO:0019001 (guanyl nucleotide binding), GO:0032561 (guanyl ribonucleotide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0042592 (homeostatic process), GO:0045494 (photoreceptor cell maintenance), GO:0048871 (multicellular organismal-level homeostasis), GO:0060249 (anatomical structure homeostasis), GO:0001894 (tissue homeostasis), GO:0001895 (retina homeostasis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0005773 (vacuole), GO:0031090 (organelle membrane), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0005774 (vacuolar membrane), GO:0098588 (bounding membrane of organelle), GO:0005764 (lysosome), GO:0098852 (lytic vacuole membrane), GO:0005765 (lysosomal membrane)
Protein: RanBP-type and C3HC4-type zinc finger-containing protein 1 (SHANK-associated RH domain-interacting protein) (X1WDE8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Sequence: MSTSTGCSTVLMSVRVSVRPLPVGSDSLRLQLSMNPNRAGLFTLTLRHTDRGGRSVSLAEFDLRSVQYELKSPRCHELRLLKPPHDCLSFSFRSEQEAQEWATVVMSSLRESHRVASICQEGLQYVKSGEKSAVLSLSMKEELCVELSRAIEAGDAQAAARYATDLAQQQMTLSIQPAPRDTDDKDISLAVIVEDASSSCCVTVKIHPHVTVASLKQQMFVEYGFHPRVQRWIISQCLCSDSRSVSSYGVCRDGDTAFLYLLSAGHASLSQQQENGLSVPTAAPANASLSAPAGGGSSGHDWRAYSTLPPRFSHASTGSGGSEKPSVTDIINLEMLQLGGSKLKSSNTQSGWPCPSCTFINKSTRPGCEICSTDRPNPPHHTHLQQEKSRRSNQ
InterPro domains: - IPR029071: Ubiquitin-like domain superfamily (homologous_superfamily) [200-270]
- IPR036443: Zinc finger, RanBP2-type superfamily (homologous_superfamily) [347-375]
- IPR031912: Sharpin, PH domain (domain) [5-115]
- IPR057468: HOIL-1/Sharpin, LUBAC thetering domain (domain) [142-181]
- IPR051628: Linear Ubiquitination-Associated E3 Ligases (family) [28-378]
- IPR001876: Zinc finger, RanBP2-type (domain) [348-377]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [1-116]
Interaction partners: - RanBP-type and C3HC4-type zinc finger-containing protein 1
- RanBP-type and C3HC4-type zinc finger-containing protein 1
- Uncharacterized protein.
- Receptor
- Tumor necrosis factor receptor superfamily, member 1a.
- Receptor-interacting serine-threonine kinase 2.
- Lymphotoxin-alpha
- X-linked inhibitor of apoptosis.
- Tnf receptor-associated factor 5.
- RING-type E3 ubiquitin transferase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0007389 (pattern specification process), GO:0003002 (regionalization), GO:0009799 (specification of symmetry), GO:0009855 (determination of bilateral symmetry), GO:0060972 (left/right pattern formation), GO:0007368 (determination of left/right symmetry)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: ARP2/3 complex subunit, putative (Q38BE7)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Sequence: MESQWNGYEESTLLGCGVYPLRRTSLDTPNGPSRPMSEVIDPIEGEGEPQDIVDEALYFLKTHLVRRAFPIRGAGDRVILYLTWYLHECIKSLVGLNRNEAQKAMLNRAVEGVVAPVDEGFVFSRFFSPGDDSEQDRWKSYATQLRVEAGSRLVEKIFLFPEEDGTGNKFWMAFAKRPFLLGG
InterPro domains: - IPR007204: Actin-related protein 2/3 complex subunit 3 (family) [3-180]
- IPR036753: Actin-related protein 2/3 complex subunit 3 superfamily (homologous_superfamily) [1-182]
Interaction partners: - Arp2/3 complex 41 kDa subunit
- Arp2/3 complex 34 kDa subunit
- Actin-like protein 3, putative
- Actin-like protein 2, putative
- Actin-related protein 2/3 complex subunit 4
- Actin-related protein 2/3 complex subunit 5
- Actin, putative
- WASH1 WAHD domain-containing protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Cutinase 3 (EC 3.1.1.74) (Ancut3) (Cutin hydrolase 3) (Q5AX00)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle (By similarity). Also degrades suberin, a specialized macromolecule found in the cell wall of various plant tissues (By similarity).
Subcellular location: Secreted {ECO:0000250|UniProtKB:P11373}.
Sequence: MRFHTILLAALASLVIATPLPSDTDVSLERRQSMNSNDLEKGDCKSVAFIFARGSTEIGNMGFVVGPGVCSNLKSTLGSDKVACQGVGGAYTAGLIQNALPANTDSGSIKEAVKMFDLAAKCPDTQIVAGGYSQGSAVIDNAIQKLDDSTRDRVKGVVLFGFTRNLQDKGQIPGYPKDQTKVYCAVGDLVCSGTLIITASHMTYGLNAGDAAKFLASQVSV
InterPro domains: - IPR043579: Cutinase, aspartate and histidine active sites (conserved_site) [184-201]
- IPR043580: Cutinase, serine active site (conserved_site) [123-135]
- IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [24-220]
- IPR000675: Cutinase/acetylxylan esterase (family) [42-219]
- IPR011150: Cutinase, monofunctional (family) [1-220]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0052689 (carboxylic ester hydrolase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009056 (catabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901575 (organic substance catabolic process), GO:0006629 (lipid metabolic process), GO:0016042 (lipid catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: ATP synthase subunit d, mitochondrial (A1ZAH1)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004273}.
Sequence: MWEKLVNCIKSNGGNGGVKNVSCQVVELADLMKQVPPNQMHKFKMFAKKHEEYKDRVRKYPESMPTIDWEYYRQNVREEFVDWVKGYETKYDKLHSVFENRHAIVDHKRYFELVDEEKKVVTKCISEYKAESDKRIQELTEKLEFVKAMRPYSEMTMEEFCFARPHLAPDFINKPTFWPHTPEEQMPGPSDPEAAAALHHEEEPEPPKKPAPEKLPDKPSGEGKPPAAAAPKEPKEPVVDTSQLAEKATLIAKDLMAKAIVLFNSLKEKMSGLAKNVQKKADAAKAARSETASKSATPTAAPTKSLDSITERESGPNICNQTIIRSEEAEANPEVKARHTNLSIEADPCDAQEERAREIARTLERKRQLKEAEEWEKHKTKKDPCDAEKETDPCKLMEEETVCKPDPCKAKEEEAVCKPDPCQQKEKEDDICKPDPCKPKDEEGSCEDEEDPCKKKPKCDGDYQFGGDNEGGSTKSKQQDQVFINISECSKELAKQEEKKSGDSGKPKEKASLSEIPQGSDQKPVLGMQITESKDSKKDHKASIEGANEIGPVYTDPNQLAELLVQKKEKPVIIEEAQKPEDDKPITIYPKLEISANPKGDQVKQEAEGQKSPKDMAKQVFTMASGAATLLTEATNTLEDLKRKKEARLEALEQAYTSAQRQAQGALAEASKAVEAANNLAIRSAEQTGEVSSRDREALEMAEKHAILAKMLAGRAVALKDEIARVLKDLKKKK
InterPro domains: - IPR008689: ATP synthase, F0 complex, subunit D, mitochondrial (family) [1-245]
- IPR036228: ATP synthase, F0 complex, subunit D superfamily, mitochondrial (homologous_superfamily) [18-148]
Interaction partners: - ATP synthase subunit gamma, mitochondrial
- ATP synthase subunit alpha, mitochondrial
- ATP synthase F
- ATP synthase subunit g
- ATP synthase F
- ATP synthase subunit b
- ATP synthase subunit g
- Putative ATP synthase subunit f
- ATP synthase, coupling factor 6-like
- ATP synthase subunit b, mitochondrial
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0003735 (structural constituent of ribosome)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006091 (generation of precursor metabolites and energy), GO:0015980 (energy derivation by oxidation of organic compounds), GO:0022900 (electron transport chain), GO:0022904 (respiratory electron transport chain), GO:0045333 (cellular respiration), GO:0019646 (aerobic electron transport chain), GO:0009060 (aerobic respiration), GO:0042773 (ATP synthesis coupled electron transport), GO:0042775 (mitochondrial ATP synthesis coupled electron transport), GO:0006119 (oxidative phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)