Protein: Immunoglobulin superfamily member 11 (IgSF11) (Brain and testis-specific immunoglobulin superfamily protein) (Bt-IGSF) (P0C673)
Organism: Mus musculus (Mouse)
Function: Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth (By similarity).
Subcellular location: Cell membrane; Single-pass type I membrane protein.
Sequence: MTRRRSAPASWLLVSLLGVATSLEVSESPGSVQVARGQTAVLPCAFSTSAALLNLNVIWMVIPLSNANQPEQVILYQGGQMFDGALRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDRGGRNIGVTGLTVLVPPSAPQCQIQGSQDLGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRSVGVIAGAVGTGAVLIVICLALISGAFFYWRSKNKEEEEEEIPNEIREDDLPPKCSSAKAFHTEISSSENNTLTSSNTYNSRYWNNNPKPHRNTESFNHFSDLRQSFSGNAVIPSIYANGNHLVLGPHKTLVVTANRGSSPQVLPRNNGSVSRKPWPQHTHSYTVSQMTLERIGAVPVMVPAQSRAGSLV
InterPro domains: - IPR013106: Immunoglobulin V-set domain (domain) [28-140]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [25-237]
- IPR007110: Immunoglobulin-like domain (domain) [23-234]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [25-237]
- IPR003598: Immunoglobulin subtype 2 (domain) [156-222]
- IPR003599: Immunoglobulin domain subtype (domain) [29-233]
- IPR042758: Immunoglobulin superfamily member 11 (family) [8-428]
Interaction partners: - V-type immunoglobulin domain-containing suppressor of T-cell activation
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0035254 (glutamate receptor binding), GO:0035255 (ionotropic glutamate receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0009987 (cellular process), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0065008 (regulation of biological quality), GO:0023056 (positive regulation of signaling), GO:0023051 (regulation of signaling), GO:0051641 (cellular localization), GO:0051239 (regulation of multicellular organismal process), GO:0033036 (macromolecule localization), GO:0048522 (positive regulation of cellular process), GO:0048584 (positive regulation of response to stimulus), GO:0051235 (maintenance of location), GO:0050794 (regulation of cellular process), GO:0070727 (cellular macromolecule localization), GO:0009967 (positive regulation of signal transduction), GO:0010647 (positive regulation of cell communication), GO:0099177 (regulation of trans-synaptic signaling), GO:0009966 (regulation of signal transduction), GO:0010646 (regulation of cell communication), GO:0045185 (maintenance of protein location), GO:0042391 (regulation of membrane potential), GO:0044057 (regulation of system process), GO:0008104 (protein localization), GO:2000463 (positive regulation of excitatory postsynaptic potential), GO:0031644 (regulation of nervous system process), GO:0098815 (modulation of excitatory postsynaptic potential), GO:0050804 (modulation of chemical synaptic transmission)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009986 (cell surface), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0005911 (cell-cell junction)