Protein: Glutamyl-tRNA(Gln) amidotransferase subunit C, chloroplastic/mitochondrial (Glu-AdT subunit C) (EC 6.3.5.-) (F4JV80)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in chloroplasts and mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Subcellular location: Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03149, ECO:0000269|PubMed:18441100, ECO:0000305|PubMed:25862457}. Plastid, chloroplast {ECO:0000255|HAMAP-Rule:MF_03149, ECO:0000269|PubMed:18441100}.
Sequence: MATRALLAVIYASPNRCYISPSRIKIQSLTCSSSSHYYQRQSRKNHRIARSYSSDSDSSVLQPPDVARLAQTARISLTPAEIEECETKIRRVIDWFGQLQQVDVNSVEPAIRAEMDGGNLREDAPETFDNRDSIRASIPSFEDAYLKVPKILNKE
InterPro domains: - IPR036113: Glu-tRNAGln amidotransferase superfamily, subunit C (homologous_superfamily) [63-151]
- IPR003837: Glu-tRNAGln amidotransferase C subunit (family) [25-155]
Interaction partners: - Nuclear pore complex protein NUP107
- Glutamyl-tRNA
- Protein SEH1
- Nuclear pore complex protein NUP160
- Nuclear pore complex protein NUP205
- Nuclear pore complex protein NUP54
- Nuclear pore complex protein NUP155
- Nuclear pore complex protein NUP88
- 1-acyl-sn-glycerol-3-phosphate acyltransferase
- Nuclear pore complex protein NUP93B
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016874 (ligase activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0005515 (protein binding), GO:0140098 (catalytic activity, acting on RNA), GO:0016879 (ligase activity, forming carbon-nitrogen bonds), GO:0016884 (carbon-nitrogen ligase activity, with glutamine as amido-N-donor), GO:0140101 (catalytic activity, acting on a tRNA)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006520 (amino acid metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044283 (small molecule biosynthetic process), GO:0006082 (organic acid metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0009072 (aromatic amino acid metabolic process), GO:0008652 (amino acid biosynthetic process), GO:0016053 (organic acid biosynthetic process), GO:0043436 (oxoacid metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0009073 (aromatic amino acid family biosynthetic process), GO:0046394 (carboxylic acid biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)