Protein: Dynein regulatory complex subunit 4 (Growth arrest-specific protein 8) (A0A087WZT7)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Cell projection, cilium, flagellum {ECO:0000256|ARBA:ARBA00004230}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Sequence: MEEAEERHQVEIKVYKQKVKHLLYEHQNNLTEMKAEGTVVMKLAQKEHRIQESVLRKDMRALKVELKEQELASEVVVKNLRLKHTEEITRMRNDFERQVREIEAKYDKKMKMLRDELDLRRKTELHEVEERKNGQIHTLMQRHEEAFTDIKNYYNDITLNNLALINSLKEQMEDMRKKEDHLEREMAEVSGQNKRLADPLQKAREEMSEMQKQLANYERDKQILLCTKARLKVREKELKDLQWEHEVLEQRFTKVQQERDELYRKFTAAIQEVQQKTGFKNLVLERKLQALSAAVEKKEVQFNEVLAASNLDPAALTLVSRKLEDVLESKNSTIKDLQYELAQVCKAHNDLLRTYEAKLLAFGIPLDNVGFKPLETAVIGQTLGQGPAGLVGTPT
InterPro domains: - IPR025593: Growth arrest-specific protein 8 domain (domain) [139-337]
- IPR039308: Growth arrest-specific protein 8 (family) [1-391]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0048870 (cell motility), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0007017 (microtubule-based process), GO:0048523 (negative regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0007018 (microtubule-based movement), GO:1903829 (positive regulation of protein localization), GO:0044085 (cellular component biogenesis), GO:0042127 (regulation of cell population proliferation), GO:0060341 (regulation of cellular localization), GO:0008285 (negative regulation of cell population proliferation), GO:0001539 (cilium or flagellum-dependent cell motility), GO:0016043 (cellular component organization), GO:0000226 (microtubule cytoskeleton organization), GO:0030030 (cell projection organization), GO:0003341 (cilium movement), GO:0032880 (regulation of protein localization), GO:0006996 (organelle organization), GO:0060285 (cilium-dependent cell motility), GO:0001578 (microtubule bundle formation), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0007010 (cytoskeleton organization), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0044782 (cilium organization), GO:0035082 (axoneme assembly), GO:0060294 (cilium movement involved in cell motility), GO:0120031 (plasma membrane bounded cell projection assembly), GO:0060271 (cilium assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0005930 (axoneme), GO:0005829 (cytosol), GO:0071944 (cell periphery), GO:0099080 (supramolecular complex), GO:0005737 (cytoplasm), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0099568 (cytoplasmic region), GO:0043228 (non-membrane-bounded organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0099081 (supramolecular polymer), GO:0043231 (intracellular membrane-bounded organelle), GO:0005929 (cilium), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0032838 (plasma membrane bounded cell projection cytoplasm), GO:0099513 (polymeric cytoskeletal fiber), GO:0031514 (motile cilium), GO:0005634 (nucleus), GO:0005856 (cytoskeleton), GO:0097014 (ciliary plasm), GO:0005874 (microtubule), GO:0015630 (microtubule cytoskeleton)