wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Nucleic acid binding protein, putative (Q383X8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MSEAIEGGPTSACGGRTGREQIHQANSLVRCSICGNVGHDKVACLSARKRPRTEEEEEALPSVCRSCGSSRHAEASCPLRMKSMECFQCHQKGHLLPMCPQTRCYNCGNYGHSSQRCLSRPLCYHCSSTGHRSTDCPLREKGRVCYRCKKPGHDMAGCSLSALCFTCNGEGHMSAQCPQISCNRCNAKGHVAAQCPQASGNRSNVKGNVVVACSKFPSVASGGSIPTVDWKRNFPTSAASGDENVVNDWSPDREEDGVDATPHAATVVSGRREIIPPFVASGAKRDGKVAVIVDGGYFERLLKGHEFRDEEQYKRCVEALRYVLDFIGEIFQKTSVAFWFDTDPSAFADYVENSMSLIHREKAFRGNSLRKRVLLDEMNGGRKLSNVVARLVGRMKRQKGYTGDGPGYVWVQTGVDVAIATCVIETFLRRQFDQVVLLCGDSDVYPAVSFCQEQRRTLQTADGPNPVRVCGTSSSISQLYGQDQDLCDFLPQILLDAPSHTEGNRTVDFPTHSVFQ
InterPro domains: - IPR042509: Zinc finger CCHC domain-containing protein 3 (family) [143-209]
- IPR001878: Zinc finger, CCHC-type (domain) [30-197]
- IPR036875: Zinc finger, CCHC-type superfamily (homologous_superfamily) [22-198]
Interaction partners: - Nucleic acid binding protein, putative
- Poly
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016787 (hydrolase activity), GO:0140098 (catalytic activity, acting on RNA), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0004518 (nuclease activity), GO:0004540 (ribonuclease activity), GO:0004519 (endonuclease activity), GO:0004521 (RNA endonuclease activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0034470 (ncRNA processing), GO:0034660 (ncRNA metabolic process), GO:0006399 (tRNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Integrin subunit alpha D (A0A8I5ZVY4)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
Sequence: TTMPFPPQSFLTLCHGFNLDTENPMTFQENARGFGQSVIQLGETRVVVAAPQEVKAVNQTGALYQCDYSTNRCDPIPLQVPPEAVNMSLGLSLAATTVPPQLLACGPTVHQNCKENTYVNGLCYLFGSNLLRKPQQFPEALRGCPQQESDIAFLIDGSGSINSIDFQKMKEFVSTVMDQFQKSKTLFSLMQYSDEFRTHFTFNDFKRNPDPKSHVRPIRQLNGRTKTASGIRKVVRELFQKINGARDNAAKILVVITDGEKFGDPLNYEDVIPEAEEAGIIRYVIGVGNAFHKPQSRRELDTIASKPAGDHVFQVDNFEALNTIRNQLQEKIFAIEGTQTGSTSSFEHEMSQEGFSAAITSNGPLLGSVGSFDWAGGAFLYPSKDKATFINTTRIDSDMNDAYLGYASAVISRNRVQSLVLGAPRYQHIGLVVMFKQNFGAWEPHTDIKGSQIGSYFGASLCSVDMDADGNTNLILIGAPHHYEKTRGGQVSVCPLPRGRARWQCEAILHGDQGHPWGRFGAALTVLGDVNGDKLTDVAIGAPGEQENQGAVYIFHGASVASISTPHSQRIAGARFSPGLQYFGQSLSGGKDLTMDGLMDLAVGAQGRLLLIRAQPVLRLEATMEFSPKNLARSVFACQEEVVKNKDAGEVRVCLHVRKNTKDRLREGDIQSTVTYDLALDPGRSVVRAFFDETKNGILRRIRVFGLTQKCETLKLILPDCVDNSVSPIILRLNYTLVGEPLRSSRDLRPVLAMEAQRIFTAMFPFEKNCGNDTICQDDLSITVSSIRVNTLVVGDSRDFDVSVTLRNDGEDSYGTKVTCYYPSGLSYRKVSASQNQFSKKPWRVIAEPSSSEGQGVLKSTIWDINHPIFPLWGAESQFLEVDKNCFPFSENNVSRTDKTESQLELPVKYAIYMVVTRCCSTPPVPSGWTPPALSLCSFAALCCSSGFFFLAFLFQNCSVAVCKRIQCDIPSFNSKEIFNVTLQGNLLFDWYIETSHDHLLLVSTAEILFNDSAFALLPGQETFVKAQTETKVEPYKVHNPVPLIVGSSVGGLVLLALITAGLYKLGFFKRQYKDMMNEAAPQDGPPQ
InterPro domains: - IPR048285: Integrin alpha, second immunoglobulin-like domain (domain) [770-837]
- IPR002035: von Willebrand factor, type A (domain) [148-333]
- IPR018184: Integrin alpha chain, C-terminal cytoplasmic region, conserved site (conserved_site) [1064-1078]
- IPR000413: Integrin alpha chain (family) [401-1071]
- IPR013649: Integrin alpha, first immunoglubulin-like domain (domain) [614-769]
- IPR028994: Integrin alpha, N-terminal (homologous_superfamily) [17-616]
- IPR048633: Integrin alpha-X-like, third Ig-like domain (domain) [957-1037]
- IPR013517: FG-GAP repeat (repeat) [520-555]
- IPR032695: Integrin domain superfamily (homologous_superfamily) [616-1033]
- IPR013519: Integrin alpha beta-propellor (repeat) [18-631]
- IPR036465: von Willebrand factor A-like domain superfamily (homologous_superfamily) [105-334]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhesion), GO:0098609 (cell-cell adhesion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009986 (cell surface)
Protein: Defective proboscis extension response 10, isoform D (M9PF17)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MLTLWTALFCCLTGLAVCYQRQSVSNNNHNNAEAKPTHAPPSHYPHGHKWNEPYFDLTMPRNITSLVGKSAYLGCRVKHLGNKTVAWIRHRDLHILTVGTYTYTTDQRFQTSYHRDIDEWTLQIKWAQQRDAGVYECQISTQPVRSYSVNLNIVVPTATILGGPDLYVDKGSTINLTCIIKFSPEPPTHIFWYHQDKVLSEETSGGRLKFKTIKSEETKSILLIYDADLLHSGKYSCYPSNTEIASIRVHVLQGERPEAMQTNAAPAAVALACWSCHFGQATQAVRVISTMVAALVLLEACSSLLLQSGGGGGCPGGGSPAGGMPTRVREIREKPLTNSLLDPKIPSTTSAERVNNGSRNAR
InterPro domains: - IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [53-242]
- IPR013098: Immunoglobulin I-set (domain) [58-148]
- IPR007110: Immunoglobulin-like domain (domain) [53-248]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [48-251]
- IPR003598: Immunoglobulin subtype 2 (domain) [66-244]
- IPR003599: Immunoglobulin domain subtype (domain) [60-252]
- IPR037448: Zwei Ig domain protein zig-8 (family) [22-288]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0034330 (cell junction organization), GO:0050808 (synapse organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0031252 (cell leading edge), GO:0031256 (leading edge membrane), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0098590 (plasma membrane region), GO:0032589 (neuron projection membrane), GO:0120025 (plasma membrane bounded cell projection), GO:0005886 (plasma membrane), GO:0043005 (neuron projection), GO:0031253 (cell projection membrane)
Protein: Photosystem I reaction center subunit XI, chloroplastic (PSI-L) (PSI subunit V) (Q9SUI4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Plastid, chloroplast membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Sequence: MAASASPMASQLRSSFSSASLSQRLAVPKGISGAPFGVSPTKRVSSFTVRAVKSDKTTFQVVQPINGDPFIGSLETPVTSSPLIAWYLSNLPGYRTAVNPLLRGVEVGLAHGFFLVGPFVKAGPLRNTAYAGSAGSLAAAGLVVILSMCLTIYGISSFKEGEPSIAPSLTLTGRKKQPDQLQTADGWAKFTGGFFFGGISGVTWAYFLLYVLDLPYFVK
InterPro domains: - IPR003757: Photosystem I PsaL, reaction centre subunit XI (domain) [61-212]
- IPR022980: Photosystem I, reaction centre subunit XI (family) [1-219]
- IPR036592: Photosystem I PsaL, reaction centre subunit XI superfamily (homologous_superfamily) [56-219]
Interaction partners: - Photosystem I reaction center subunit psaK, chloroplastic
- Photosystem I P700 chlorophyll a apoprotein A1
- Photosystem I reaction center subunit IV A, chloroplastic
- Photosystem I chlorophyll a/b-binding protein 2, chloroplastic
- Photosystem I chlorophyll a/b-binding protein 3-1, chloroplastic
- Photosystem I reaction center subunit N, chloroplastic
- Photosystem I reaction center subunit VI-2, chloroplastic
- Photosystem I reaction center subunit V, chloroplastic
- Photosystem I subunit O
- Chlorophyll a-b binding protein 4, chloroplastic
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051641 (cellular localization), GO:0071840 (cellular component organization or biogenesis), GO:0044237 (cellular metabolic process), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0016043 (cellular component organization), GO:0006091 (generation of precursor metabolites and energy), GO:0015979 (photosynthesis), GO:0008104 (protein localization), GO:0006996 (organelle organization), GO:0019684 (photosynthesis, light reaction), GO:0061024 (membrane organization), GO:0009668 (plastid membrane organization), GO:0009657 (plastid organization), GO:0010027 (thylakoid membrane organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0005737 (cytoplasm), GO:0031967 (organelle envelope), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009526 (plastid envelope), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle), GO:0009941 (chloroplast envelope)
Protein: Insulin-like growth factor 2 preproprotein (Q2F6J8)
Organism: Bos taurus (Bovine)
Function: Not known
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Sequence: MGITAGKSVLVLLAFLAFASCCYAAYRPSETLCGGELVDTLQFVCGDRGF
InterPro domains: - IPR016179: Insulin-like (domain) [30-50]
- IPR036438: Insulin-like superfamily (homologous_superfamily) [16-50]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009719 (response to endogenous stimulus), GO:0042221 (response to chemical), GO:1901698 (response to nitrogen compound), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:1901700 (response to oxygen-containing compound), GO:0043434 (response to peptide hormone), GO:1901652 (response to peptide), GO:0010243 (response to organonitrogen compound), GO:0032868 (response to insulin)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: White collar 1 (Q5EGQ2)
Organism: Cryptococcus neoformans var. neoformans
Function: Not known
Sequence: SVDYTYSIPPEKPLQLDGKGAAIAGLSTAVLDIMGSRTKALAAGTEEGARMEWFKMILDNTDDFIHALSLKGFFQYASSSIRRSLGYEPEDLLNKNISEFAHPSDIVPVIRALKDSTQTIGEEQQPKPVHFTFRIRTKNFGYVWVESMGRLVVEAGKGRKAVILSGRVRNMPTLSWGKVAEHGGLAKTEFWAKISFQGLLLNLTFGVDKVLGYQAEEILGRNLFSLLPGGQNTPPSGEHLINNYASAPDIAPVAKAIYQTIHDSTHRGALSIRQKMVHRSGQPVDVILVFYAPGQAKDKQSPISYSNNDESASVNFIGTPNGASTYPVKITDIFVQVKLLSSSPSHQRSVQPPSIASLTQARPLVHLPNDNIFEELETGRDSSWQYELHQMKMTNRRLRDSIAALKEKKAGKAKKRKYNIVDESPENQSEIIDTSLSSQIGGIGF
InterPro domains: - IPR035965: PAS domain superfamily (homologous_superfamily) [57-158]
- IPR000014: PAS domain (domain) [50-245]
- IPR013655: PAS fold-3 (domain) [76-157]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0048523 (negative regulation of cellular process), GO:0009892 (negative regulation of metabolic process), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0051252 (regulation of RNA metabolic process), GO:0051253 (negative regulation of RNA metabolic process), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:0010468 (regulation of gene expression), GO:2001141 (regulation of RNA biosynthetic process), GO:1902679 (negative regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903507 (negative regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045892 (negative regulation of DNA-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: GTPase IMAP family member 1 (Immunity-associated protein 1) (hIMAP1) (Q8WWP7)
Organism: Homo sapiens (Human)
Function: May regulate lymphocyte survival. Required for normal levels of mature T-lymphocytes and mature B-cells (By similarity).
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P70224}; Single-pass type IV membrane protein {ECO:0000305}. Golgi apparatus membrane {ECO:0000250|UniProtKB:P70224}; Single-pass type IV membrane protein {ECO:0000305}.
Sequence: MGGRKMATDEENVYGLEENAQSRQESTRRLILVGRTGAGKSATGNSILGQRRFFSRLGATSVTRACTTGSRRWDKCHVEVVDTPDIFSSQVSKTDPGCEERGHCYLLSAPGPHALLLVTQLGRFTAQDQQAVRQVRDMFGEDVLKWMVIVFTRKEDLAGGSLHDYVSNTENRALRELVAECGGRVCAFDNRATGREQEAQVEQLLGMVEGLVLEHKGAHYSNEVYELAQVLRWAGPEERLRRVAERVAARVQRRPWGAWLSARLWKWLKSPRSWRLGLALLLGGALLFWVLLHRRWSEAVAEVGPD
InterPro domains: - IPR045058: GTPase GIMA/IAN/Toc (family) [29-234]
- IPR006703: AIG1-type guanine nucleotide-binding (G) domain (domain) [25-229]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [24-253]
Interaction partners: - GTPase IMAP family member 8
- GTPase IMAP family member 7
- GTPase IMAP family member 6
- GTPase IMAP family member 4
- GTPase IMAP family member 2
- GTPase IMAP family member 5
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0007005 (mitochondrion organization), GO:0000002 (mitochondrial genome maintenance)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Co-chaperone protein DjlA (DnaJ-like protein DjlA) (P31680)
Organism: Escherichia coli (strain K12)
Function: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
Subcellular location: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_01153, ECO:0000269|PubMed:11106641, ECO:0000269|PubMed:8809778, ECO:0000269|PubMed:9364917}; Single-pass type III membrane protein {ECO:0000255|HAMAP-Rule:MF_01153, ECO:0000269|PubMed:11106641, ECO:0000269|PubMed:8809778, ECO:0000269|PubMed:9364917}.
Sequence: MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWFANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFRVGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEELGISRAQFDQFLRMMQGGAQFGGGYQQQTGGGNWQQAQRGPTLEDACNVLGVKPTDDATTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK
InterPro domains: - IPR023749: Co-chaperone DjlA (family) [3-270]
- IPR050817: DjlA DnaK co-chaperone (family) [49-264]
- IPR036869: Chaperone J-domain superfamily (homologous_superfamily) [131-269]
- IPR007791: Co-chaperone DjlA, N-terminal (domain) [62-170]
- IPR001623: DnaJ domain (domain) [204-271]
- IPR029024: TerB-like (homologous_superfamily) [36-183]
Interaction partners: - Curved DNA-binding protein
- Chaperone protein DnaJ
- Chaperone protein DnaK
- Chaperone protein HscC
- Sensor histidine kinase RcsC
- Chaperone SurA
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030234 (enzyme regulator activity), GO:0005515 (protein binding), GO:0140678 (molecular function inhibitor activity), GO:0019899 (enzyme binding), GO:0004857 (enzyme inhibitor activity), GO:0044389 (ubiquitin-like protein ligase binding), GO:0031625 (ubiquitin protein ligase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0033554 (cellular response to stress), GO:0006974 (cellular response to DNA damage stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Splicing factor ESS-2 homolog (DiGeorge syndrome critical region 13) (DiGeorge syndrome critical region 14) (DiGeorge syndrome protein H) (DGS-H) (Protein ES2) (Q96DF8)
Organism: Homo sapiens (Human)
Function: May be involved in pre-mRNA splicing.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P34420}.
Sequence: METPGASASSLLLPAASRPPRKREAGEAGAATSKQRVLDEEEYIEGLQTVIQRDFFPDVEKLQAQKEYLEAEENGDLERMRQIAIKFGSALGKMSREPPPPYVTPATFETPEVHAGTGVVGNKPRPRGRGLEDGEAGEEEEKEPLPSLDVFLSRYTSEDNASFQEIMEVAKERSRARHAWLYQAEEEFEKRQKDNLELPSAEHQAIESSQASVETWKYKAKNSLMYYPEGVPDEEQLFKKPRQVVHKNTRFLRDPFSQALSRCQLQQAAALNAQHKQGKVGPDGKELIPQESPRVGGFGFVATPSPAPGVNESPMMTWGEVENTPLRVEGSETPYVDRTPGPAFKILEPGRRERLGLKMANEAAAKNRAKKQEALRRVTENLASLTPKGLSPAMSPALQRLVSRTASKYTDRALRASYTPSPARSTHLKTPASGLQTPTSTPAPGSATRTPLTQDPASITDNLLQLPARRKASDFF
InterPro domains: - IPR019148: Nuclear protein DGCR14/ESS-2 (family) [24-465]
Interaction partners: - Integral membrane protein DGCR2/IDD
- Glutamine amidotransferase-like class 1 domain-containing protein 3
- Transcription factor SOX-2
- Protein FRA10AC1
- Estrogen receptor
- Tricarboxylate transport protein, mitochondrial
- Protein HIRA
- Polycomb protein SUZ12
- Ubiquitin recognition factor in ER-associated degradation protein 1
- Tetratricopeptide repeat protein 14
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0008380 (RNA splicing), GO:0006397 (mRNA processing), GO:0016071 (mRNA metabolic process), GO:0000398 (mRNA splicing, via spliceosome), GO:0000375 (RNA splicing, via transesterification reactions), GO:0000377 (RNA splicing, via transesterification reactions with bulged adenosine as nucleophile)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)