Protein: GAD67 (Glutamate decarboxylase 1 (EC 4.1.1.15)) (Glutamate decarboxylase 1b isoform X1) (Q7ZUS3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Sequence: MASSAPSSSAGDMDPNTANLRQPATTSDAWYGVAHGCTRKLGMKICGFLQKNNSLDEKSRMVGSFKESAKNQMSCDNNERFTRDETDFSNLFARDLLPAKNGEEPTIQFLLEVVEILTNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDQPESLEQILVDCRDTLKYGVRTGHPRFFNQLSSGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQLTLKKMREIIGWPNGDGDALFSPGGAISNMYSVMVARYKYFPEVKTKGMSAAPRLVLFTSEHSHYSIKKAGAVLGFGKENVILLKTDERGRVIPADLEAKVIDAKQKGYVPLFVNATAGTTVYGAFDPINDIADICEKYNLWLHVDGAWGGGLLMSRKHRHKLSGIERANSVTWNPHKMMGVPLQCSAILVREKGILQGCNSMCAGYLFQPDKQYDVTYDTGDKAIQCGRHVDIFKFWLMWKAKGTIGFEQHIDRCLELSEYLYNKIKNREGYEMVFEGQPQHTNVCFWYIPPSLRGMPNGDERREKLHRVAPKIKAMMMECGTTMVGYQPQGDKVNFFRMVVSNHAVTKSDIDFLIDEIERLGQDL
InterPro domains: - IPR015421: Pyridoxal phosphate-dependent transferase, major domain (homologous_superfamily) [204-452]
- IPR021115: Pyridoxal-phosphate binding site (binding_site) [391-412]
- IPR002129: Pyridoxal phosphate-dependent decarboxylase (family) [144-510]
- IPR015424: Pyridoxal phosphate-dependent transferase (homologous_superfamily) [107-586]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016830 (carbon-carbon lyase activity), GO:0016831 (carboxy-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0009987 (cellular process), GO:0065008 (regulation of biological quality), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0042133 (neurotransmitter metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0006082 (organic acid metabolic process), GO:0001505 (regulation of neurotransmitter levels), GO:0044249 (cellular biosynthetic process), GO:0006520 (amino acid metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0008652 (amino acid biosynthetic process), GO:0016053 (organic acid biosynthetic process), GO:0009448 (gamma-aminobutyric acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process), GO:0032787 (monocarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0120025 (plasma membrane bounded cell projection), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0012506 (vesicle membrane), GO:0043005 (neuron projection), GO:0030135 (coated vesicle), GO:0031982 (vesicle), GO:0030659 (cytoplasmic vesicle membrane), GO:0097708 (intracellular vesicle), GO:0030136 (clathrin-coated vesicle), GO:0030662 (coated vesicle membrane), GO:0030424 (axon), GO:0030665 (clathrin-coated vesicle membrane)