Protein: Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12) (A0A1D8PIP6)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MPSDETISKSNGNIHIATNNINGVGPTTTTDQLDISDQSSTLLHNKINFVRELTPRPDNYSSINSCNHIESVLGTKAKNTVFETYRQAVLISQPIINNNNNNNNNNNNNNNNNTNNNNYKSIYKLKKDGSIIPIEKLINSKNLVLKCHQCHLNNFGNSMICLQCPHVGCCFNDYNHSYSHYKSTKHMFSIDSSCGLLYCFKCNDFINHPELEKIRLQIVLGEHDEEKKKKKKKTTTTTTVDDDDDDDDDFIKQNYVDPGQIAIKGLKGFVNLGATCFMSSILQTLIHNPLIKYQFFNNDLHYFNCEKFHNQFINQGNIDENNACITCSIDNIFQSFYTSTTNEGFGMTNLLTTAWYKQKSLAGFEEQDAHEFWQFLLNEFHMDYQRIINNLNSNSNSNSNSNQDNNEKNTHSSNDDSVVNSCGCIMHSTFSFELQSCIKCDSCDSITETVDPMIDLSLEVNFTNLYQSLQSFTRDEKLDDYNCKNCNNSNNNKSTTTTSAIKKLRLKTLPQILSIQLKRFRHDILGSFQATKIQSHINFPLFLNVTEYSVIKDTDYIYQLFAVVCHQGSINTGHYTVFIKNNSNWYKFDDSVVTMVSQDVVINSEAYLLYYIV
InterPro domains: - IPR018200: Ubiquitin specific protease, conserved site (conserved_site) [268-575]
- IPR001394: Peptidase C19, ubiquitin carboxyl-terminal hydrolase (domain) [268-611]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [59-223]
- IPR001607: Zinc finger, UBP-type (domain) [114-225]
- IPR038765: Papain-like cysteine peptidase superfamily (homologous_superfamily) [265-611]
- IPR028889: Ubiquitin specific protease UPS, catalytic domain (domain) [267-613]
- IPR050185: Ubiquitin carboxyl-terminal hydrolase (family) [83-611]
Interaction partners: - Deubiquitination module subunit
- SGF29 C-terminal domain-containing protein
- Transcription and mRNA export factor SUS1
- SAGA histone acetyltransferase complex subunit
- Histone acetyltransferase GCN5
- Histone acetyltransferase
- Transcription initiation factor TFIID subunit 10
- Histone acetyltransferase
- Protein SPT3
- Transcription initiation factor TFIID subunit 9
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008234 (cysteine-type peptidase activity), GO:0019783 (ubiquitin-like protein peptidase activity), GO:0101005 (deubiquitinase activity), GO:0004843 (cysteine-type deubiquitinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044248 (cellular catabolic process), GO:0019538 (protein metabolic process), GO:0016043 (cellular component organization), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:0009057 (macromolecule catabolic process), GO:0043412 (macromolecule modification), GO:1901565 (organonitrogen compound catabolic process), GO:0006508 (proteolysis), GO:0044265 (cellular macromolecule catabolic process), GO:0030163 (protein catabolic process), GO:0006325 (chromatin organization), GO:0070647 (protein modification by small protein conjugation or removal), GO:0043632 (modification-dependent macromolecule catabolic process), GO:0051603 (proteolysis involved in protein catabolic process), GO:0016570 (histone modification), GO:0019941 (modification-dependent protein catabolic process), GO:0006511 (ubiquitin-dependent protein catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:1902494 (catalytic complex), GO:0140535 (intracellular protein-containing complex), GO:0031248 (protein acetyltransferase complex), GO:1990234 (transferase complex), GO:0043229 (intracellular organelle), GO:0000123 (histone acetyltransferase complex), GO:0043228 (non-membrane-bounded organelle), GO:1902493 (acetyltransferase complex), GO:1902562 (H4 histone acetyltransferase complex), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome), GO:0043189 (H4/H2A histone acetyltransferase complex), GO:0035267 (NuA4 histone acetyltransferase complex)