wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: E3 ubiquitin-protein ligase Os06g0535400 (EC 2.3.2.27) (RING-H2 finger protein Os06g0535400) (RING-type E3 ubiquitin transferase Os06g0535400) (Q5Z5F2)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Possesses E3 ubiquitin-protein ligase in vitro.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Sequence: MELPWLDLPFTLLTLLLATRLAYDYYGVVAATFTGSFSLQIFLFYCFARWYRHTIAARAAADADGDGGGGAVADEEAAPPVLIPLLEGRGGGGGGAGAASSLANRCFAVVFMVFVPLVIVVFERSQADVVAYALCLANILVMVVWLSPDAAADPASAAKSFLRLSDDEDEGSCSGSGHGAAEDKCCVCLAGMREAQALRDLPRCGHRFHAKCIGKWLTAHPTCPVCRTTAVPPPAPLPASGDHADDAITPV
InterPro domains: - IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [152-232]
- IPR001841: Zinc finger, RING-type (domain) [183-227]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0090698 (post-embryonic plant morphogenesis), GO:0099402 (plant organ development), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:1905392 (plant organ morphogenesis), GO:0043170 (macromolecule metabolic process), GO:0048731 (system development), GO:0090696 (post-embryonic plant organ development), GO:0010311 (lateral root formation), GO:0036211 (protein modification process), GO:0048364 (root development), GO:0043412 (macromolecule modification), GO:0010015 (root morphogenesis), GO:0090697 (post-embryonic plant organ morphogenesis), GO:0022622 (root system development), GO:0070647 (protein modification by small protein conjugation or removal), GO:0032446 (protein modification by small protein conjugation), GO:0016567 (protein ubiquitination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Autophagy-related protein 9 (Q3T903)
Organism: Caenorhabditis elegans
Function: Not known
Subcellular location: Preautophagosomal structure membrane {ECO:0000256|ARBA:ARBA00004511, ECO:0000256|RuleBase:RU364027}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004511, ECO:0000256|RuleBase:RU364027}.
Sequence: MAETQNLLQKIDNSSINLIFFQKKTHQMFNSQSKRAYQQIDDDFDDEVLRNSTCTSRFMQGWGSSTRSLLFGGASNDEQRNLIASSSSHHSYHDSPAEEPPETHYEQFTATHNHGPPTMASSSQLNSRRWDHVLNLDEFFTHIYEYHQNGGYLCIVLQKVFSLLQFIFVMSFTTFFTQCVNYQFLFANTNVTSHGTVNQGKRHFGDAVVDNCPAHISIWMIFAILAAIVYWITRVIKHAQYIMKMSEIQQFYAHELKIADDQLPNLTWHAIVKRICEAQKKLRLSIHQDNITSIYIYHRILRYKNYMTGMINKRILHPVFDVPFLGPIAYLPNNLKHEIERILFTSSTSAWTNGPNLREEYKHHEQLDMAAKKMKEDVINLFLQILRISVARPDASTAPIPDYGIVLLTDGAHKKTTRWAWNEKIQYLLRHFNELDHELSARLNRSHIYAAAYMDQFFSPVLEIAAKNITFIAAAVFGVLTILSAWDEDVLQVEHVITVLTICGIVVLVCRGMIPDENLVWQPEILMTHVTSELHYLPSTWKGKAHTTGVRHEFDQLFQMKWMFFVLELTSPIFTPFVLLFWLRPRCSQLANFFHDYTERVDGLGDVCSFAVMDVGKHGDPKWNHIKELKAIVEDQEDQQQAQSVVTSLNRARDGKTELSILHFKTTNPEWQPPKASEKFLRKFRNRLGQEASMLAPLTSMHLGQQMDRQQQQGKIGRNILLESVHSIVPTTSGGISASQVAPGRHPLIGDGLHRIDGPVGNAFQGIQGAKLGSGGVLASLYQEQPRAAESLSNSLRASGVDIDGAGAEMRINALFLRGLHDESIIHSSSRNYGGTTSSFNMHPTAMQSVFAMPDGFGQPAPAVESSLIDIETPTYHRESVQRSAAEHKMEHETPEPLAELPDLPGPSSSEHQQRSRLVPNTQHRQINEEEEEEEEEDNTPPLSFSS
InterPro domains: - IPR007241: Autophagy-related protein 9 (family) [129-753]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0065008 (regulation of biological quality), GO:0050794 (regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0050803 (regulation of synapse structure or activity), GO:0044087 (regulation of cellular component biogenesis), GO:0050807 (regulation of synapse organization), GO:1901888 (regulation of cell junction assembly), GO:0099174 (regulation of presynapse organization), GO:0051963 (regulation of synapse assembly), GO:1905606 (regulation of presynapse assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0098793 (presynapse), GO:0005737 (cytoplasm), GO:0030054 (cell junction), GO:0045202 (synapse)
Protein: Derlin (B4E1G1)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU363059}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477, ECO:0000256|RuleBase:RU363059}.
Sequence: MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGDQ
InterPro domains: - IPR007599: Derlin (family) [46-104]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0006984 (ER-nucleus signaling pathway), GO:0006991 (response to sterol depletion), GO:0033554 (cellular response to stress), GO:0032933 (SREBP signaling pathway), GO:0071501 (cellular response to sterol depletion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: S-protein homolog 22 (Q9LW23)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Secreted {ECO:0000305|PubMed:10344198}.
Sequence: MKYFTIFFIFFSLCMFGHVSGAGIRIVNELKNKKTLWMRCYSKNDVLGPTIIPNGGQFTDYFFHNLFGTTRFMCTLKQGPGFSHSQSFRAFKNSGLWDWRAREDGIYLRRIYKTKFDDDTDNLHKEQSWI
InterPro domains: - IPR010264: Plant self-incompatibility S1 (family) [24-129]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0001666 (response to hypoxia), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0070482 (response to oxygen levels), GO:0071456 (cellular response to hypoxia), GO:0071453 (cellular response to oxygen levels), GO:0036293 (response to decreased oxygen levels), GO:0036294 (cellular response to decreased oxygen levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle)
Protein: ATP-dependent Clp protease proteolytic subunit 1 (EC 3.4.21.92) (Endopeptidase Clp 1) (Q9I2U1)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00444}.
Sequence: MSRNSFIPHVPDIQAAGGLVPMVVEQSARGERAYDIYSRLLKERIIFLVGQVEDYMANLVVAQLLFLEAENPEKDIHLYINSPGGSVTAGMSIYDTMQFIKPNVSTTCIGQACSMGALLLAGGAAGKRYCLPHSRMMIHQPLGGFQGQASDIEIHAKEILFIKERLNQILAHHTGQPLDVIARDTDRDRFMSGDEAVKYGLIDKVMTQRDLAV
InterPro domains: - IPR029045: ClpP/crotonase-like domain superfamily (homologous_superfamily) [27-210]
- IPR001907: ATP-dependent Clp protease proteolytic subunit (family) [19-209]
- IPR018215: ClpP, Ser active site (active_site) [106-117]
- IPR023562: Clp protease proteolytic subunit /Translocation-enhancing protein TepA (family) [18-209]
- IPR033135: ClpP, histidine active site (active_site) [128-141]
Interaction partners: - ATP-dependent Clp protease ATP-binding subunit ClpX
- ATP-binding protease component ClpA
- Chaperonin GroEL
- Co-chaperonin GroES
- Chaperone protein DnaK
- Chaperone protein ClpB
- Lon protease
- ATP-dependent Clp protease adapter protein ClpS
- ATP-dependent protease ATPase subunit HslU
- Lon protease
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0017171 (serine hydrolase activity), GO:0008233 (peptidase activity), GO:0008236 (serine-type peptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0006508 (proteolysis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0016020 (membrane), GO:0005829 (cytosol), GO:1902494 (catalytic complex), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0140535 (intracellular protein-containing complex), GO:0043233 (organelle lumen), GO:0000502 (proteasome complex), GO:1905368 (peptidase complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:1905369 (endopeptidase complex), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3) (Q9D8S3)
Organism: Mus musculus (Mouse)
Function: GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment. {ECO:0000250}.
Sequence: MGDPSKQDILAIFKRLRSVPTNKVCFDCGAKNPSWASISYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQLRCMQVGGNSNASSFFHQHGCATKDTNAKYNSRAAQLYREKIKTLATQATRRHGTDLWLDSCAAPPVSPPPKEEDFFASHASLEVSGAMQASAQPESASSTPWGLETTPEKHEGGPGQGPSVEGLNTPGKAAPEVSSIIKKKPNQAKKGLGAKKGSLGAQKLTNTSFTEIEKQAQAVDKRKEQEDLARGAPKEESIVSSLRLAYKDLEISRKKDERLNLSGQKKVEAERLGMGFGSCRSGISHSVTSDMQTIEQESPTLAKPRRKYQEDPEDSYFSSSSKWSEQSSRYFDDPMELRSSSFSSWDDGADSYWKKDSSRDPEPAMRSTGSSDRPSARRKPEYEPIGSTDEAQKKFGNVKAISSDMYFGIQAQTDFETRARLERLSTSSSISSADLFDEQRKQTAGNYNLSNVLPNAPDMAQFKQGVRSVAGKLSVFANGVMTSIQDRYGS
InterPro domains: - IPR037278: ARFGAP/RecO-like zinc finger (homologous_superfamily) [12-114]
- IPR001164: Arf GTPase activating protein (domain) [10-126]
- IPR038508: ArfGAP domain superfamily (homologous_superfamily) [1-141]
Interaction partners: - Coatomer subunit beta
- Coatomer subunit beta'
- ADP-ribosylation factor 1
- ADP-ribosylation factor GTPase-activating protein 1
- Coatomer subunit delta
- Coatomer subunit gamma-1
- Coatomer subunit gamma-2
- Coatomer subunit alpha
- ADP-ribosylation factor 4
- ADP-ribosylation factor 5
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0140352 (export from cell), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0032940 (secretion by cell), GO:0045184 (establishment of protein localization), GO:0006810 (transport), GO:0035592 (establishment of protein localization to extracellular region), GO:0071702 (organic substance transport), GO:0046903 (secretion), GO:0008104 (protein localization), GO:0071705 (nitrogen compound transport), GO:0009306 (protein secretion), GO:0015031 (protein transport), GO:0071692 (protein localization to extracellular region)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0000139 (Golgi membrane), GO:0043231 (intracellular membrane-bounded organelle)
Protein: MPP4 protein (A2RU80)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MIQSDKGADPPDKKDMKLSTATNPQNGLSQILRLVLQELSLFYSRDVNGVCLLYDLLHSPWLQALLKIYDCLQEFKEKKLVPATPHAQVLSYEVVELLRETPTSPEIQELRQMLQAPHFKALLSAHDTIAQKDFEPLLPPLPDNIPESEEAMRIVCLVKNQQPLGATIKRHEMTGDILVARIIHGGLAERSGLLYAGDKLVEVNGVSVEGLDPEQVIHILAMSRGTIMFKVVPVSDPPVNSQQMVYVRAMTEYWPQEDPDIPCMDAGLPFQKGDILQIVDQNDALWWQARKISDPATCAGLVPSNHLLKRKQREFWWSQPYQPHTCLKSTLSISMEEEDDMKIDEKCVEAEELSEDKEEFVGYGQKFFIAGFRRSMRLCRRKSHLSPLHASVCCTGSCYSAVGAPYEEVVRYQRRPSDKYRLIVLMGPSGVGVNELRRQLIEFNPSHFQSAVPHTTRTKKSYEMNGREYHYVSKETFENLIYSHRMLEYGEYKGHLYGTSVDAVQTVLVEGKICVMDLEPQDIQGVRTHELKPYVIFIKPSNMRCMKQSRKNAKIITDYYVDMKFKDEDLQEMENLAQRMETQFGQFFDHVIVNDSLHDACAQLLSAIQKAQEEPQWVPATWISSDTESQ
InterPro domains: - IPR036034: PDZ superfamily (homologous_superfamily) [130-236]
- IPR008144: Guanylate kinase-like domain (domain) [420-609]
- IPR036892: L27 domain superfamily (homologous_superfamily) [86-136]
- IPR036028: SH3-like domain superfamily (homologous_superfamily) [219-338]
- IPR035600: MPP4, SH3 domain (domain) [246-306]
- IPR001452: SH3 domain (domain) [242-312]
- IPR020590: Guanylate kinase, conserved site (conserved_site) [455-472]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [407-624]
- IPR014775: L27 domain, C-terminal (domain) [90-138]
- IPR050716: Membrane-associated guanylate kinase (family) [20-623]
- IPR008145: Guanylate kinase/L-type calcium channel beta subunit (domain) [419-612]
- IPR001478: PDZ domain (domain) [154-235]
- IPR004172: L27 domain (domain) [24-140]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0046907 (intracellular transport), GO:0051668 (localization within membrane), GO:0045184 (establishment of protein localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0008104 (protein localization), GO:0015031 (protein transport), GO:0090150 (establishment of protein localization to membrane), GO:0072657 (protein localization to membrane), GO:0006612 (protein targeting to membrane), GO:0006605 (protein targeting)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0030054 (cell junction), GO:0043229 (intracellular organelle), GO:0070161 (anchoring junction), GO:0043228 (non-membrane-bounded organelle), GO:0005911 (cell-cell junction), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0005912 (adherens junction), GO:0015629 (actin cytoskeleton)
Protein: Epsin (Q54EH1)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2).
Subcellular location: Membrane, clathrin-coated pit {ECO:0000269|PubMed:18827012}.
Sequence: METMIKSYIKKGKDAVLNTPEIERKVRDATSNDKWGPSGTQMQEISRASYNYECFPIIMGVIWKRINDPGKFWRHVYKSLLLIDYLVRNGSPQVIRDCRHHTMEIKTLVEFQYIEEEKDVGLSVRERAKQVIDLLQDDQRIKEERDKAKTNQNKYVGIGNDSRDFGYGGGSYGGGGYDSDSYGSNQRDSYGGNQRDSYGGNQRDSYGGNQRETTRRDSFNGRDEGYGNNNNNNNNNSYDSDPYSNTRAEYENYSNRAETRRNNEFGDDSNNSYNNNNNFNNNNNNNNSYNNSNNSNNSNNNNNNNNYNNSNNNSNNIQNNPNAASGGRSRPRAASGSGPSPATPNFQSSQQQQQPTLIDFSEPTPANKPMVFDPLADLASGMNNTNNNNNNNNNNSNSFGGFQSVNNNQNSFNFNNNNQQQQQQNNFLQLTQSNPQQSNNNNNNNNFFNQQPQQAQQFGQFQNSSMNKDPFAKDEFGDFAGANGNADFNPFDQQSGDFSNKNDGQQKPKDTNDPWSKKDLFDLSNLGNQNPNQSPVNNTNNNNNGNTRSQPARVANGPITSAGSTIPTMRPQPMMNQGFNGGMMNQGMGGFNQGGGMNNMNGMNQGGMNNMNGMNQGGMNQGGMGGFNQGGMNNMGGMNQGGMNNMGGMNNMGGMNSMNGMNQGGMGFNQSGANRNTNSMGSAGRF
InterPro domains: - IPR013809: ENTH domain (domain) [14-145]
- IPR008942: ENTH/VHS (homologous_superfamily) [13-159]
Interaction partners: - Clathrin heavy chain
- ANTH domain-containing protein
- AP-2 complex subunit alpha-2
- Clathrin light chain
- AP-1 complex subunit gamma
- AP-1 complex subunit beta
- AP-2 complex subunit mu
- AP-3 complex subunit delta
- Epidermal growth factor receptor substrate 15 homolog
- AP-3 complex subunit beta
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0008289 (lipid binding), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0030276 (clathrin binding), GO:0005543 (phospholipid binding), GO:0043168 (anion binding), GO:0035091 (phosphatidylinositol binding), GO:0080025 (phosphatidylinositol-3,5-bisphosphate binding), GO:1901981 (phosphatidylinositol phosphate binding), GO:0032266 (phosphatidylinositol-3-phosphate binding), GO:1902936 (phosphatidylinositol bisphosphate binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport), GO:0006996 (organelle organization), GO:0061024 (membrane organization), GO:0006900 (vesicle budding from membrane), GO:0016050 (vesicle organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0030139 (endocytic vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle), GO:0045335 (phagocytic vesicle)
Protein: Sorting nexin 1 (H0YKD5)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MASGGGGCSASERLPPPFPGLEPESEGAAGGSEPEAGDSDTEGEDIFTGAAVVSKHQSPKITTSLLPINNGSKENGIHEEQDQEPQDLFADKLTIVQKQTVCSKKKI
InterPro domains: - IPR005329: Sorting nexin, N-terminal (domain) [10-90]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009894 (regulation of catabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0031329 (regulation of cellular catabolic process), GO:0010506 (regulation of autophagy)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005773 (vacuole), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0005764 (lysosome), GO:0097708 (intracellular vesicle)