Protein: Esc4p (Q5ALY1)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Sequence: MFQNCNFLIIKSKQLTQDKDLSQLLLANNVANIYIKDDFDNSKNYMDPPKITHIISNTIDFIEHDLAIKSMIPIVTPSWVYDSISSQKMQNIRTYNPDPAYFFKDCFICCADNLPPGDKELIYAAAQAFGGGYLDNITKYTTHLIAMDISNEKSILASSIIHDDDDNDSNGDMPNIKIVLPHWIDHCITMGKKLNEDNYLLPDAKILHDESNDVLKNEILPEILNDSLPPQNELDSELQFFKNKKFYINSDFNLSQRSSNAIKFVIERHGGSIIKKFDVSEIDIYLGKYRQGDTYKKSCASNRIIVGNLQWLYFILASKSWTLPLNSNILYYPQPSTPLDGLQGLKISITNYSGEARSYLSKLITIMGGVFTKTLTRDNDYLVCGKAEGKKFDAALNKWVDSEGNSEIKVVNHLWLEDCYVQWHKVDSSLDKYKNFGDESIGMEPWVGRAHLDQEVLKQWYEDEEKTASNSSGNIDDSMSEDESTQSRRGATTKEQLDHSQTSEPVNVEEKNIVTPSSSQPANQPVSPISTTSNKTVKSTTETTPELNLSSQTQKEFSRESSSSPIIATKSLSSRYGERSAAKKATAKLHDNMSDLIAYQEMTKSSRKMKSYMDQLEGSLTPSKKRKHSEDQEEQEDEDEDENDEHGDEIEELSQSDFLKTKKKTQYHIIAIMSGCEQIIELSKSDIQKLRTIGIKIVNDIDNNTSLNTLIAPKILRTEKFLRSLSKVDKIIHPNYLVNIINHISSKGDTETVFKEYRIDDYSLDKVNKNTNLELGYSTNSKFINGMQILLCHNDKKGKLFQGMNFNLSSNLNGGIDVISRVLKDHGMNKYKEIKTPNNLSKSLIKTNYKSDEKIILIANKKKDTKLINNFKKSVKSGIILEWDWCVKSIFKMELQDFKKFQI
InterPro domains: - IPR001357: BRCT domain (domain) [1-903]
- IPR053036: Cell Cycle and DNA Repair Regulator (family) [2-902]
- IPR031906: Regulator of Ty1 transposition protein 107, BRCT domain (domain) [799-896]
- IPR036420: BRCT domain superfamily (homologous_superfamily) [1-903]
Interaction partners: - Chromatin-binding protein
- DNA repair protein
- Protein kinase activating protein
- Serine/threonine-protein kinase TEL1
- DNA 3'-5' helicase
- DNA repair protein RAD51 homolog
- Double-strand break repair protein
- DNA repair protein RAD50
- DNA 3'-5' helicase
- Ash2p
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0044237 (cellular metabolic process), GO:0019222 (regulation of metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0030447 (filamentous growth), GO:0006950 (response to stress), GO:0045926 (negative regulation of growth), GO:0071704 (organic substance metabolic process), GO:0048523 (negative regulation of cellular process), GO:0040008 (regulation of growth), GO:0044238 (primary metabolic process), GO:0036166 (phenotypic switching), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0033554 (cellular response to stress), GO:0010570 (regulation of filamentous growth), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:2000220 (regulation of pseudohyphal growth), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0090304 (nucleic acid metabolic process), GO:0006974 (cellular response to DNA damage stimulus), GO:0031326 (regulation of cellular biosynthetic process), GO:1900429 (negative regulation of filamentous growth of a population of unicellular organisms), GO:0006259 (DNA metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:1900428 (regulation of filamentous growth of a population of unicellular organisms), GO:0051252 (regulation of RNA metabolic process), GO:0010468 (regulation of gene expression), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0006281 (DNA repair), GO:0006357 (regulation of transcription by RNA polymerase II), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0071944 (cell periphery), GO:0140535 (intracellular protein-containing complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0030312 (external encapsulating structure), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)