Protein: 6-oxocyclohex-1-ene-1-carbonyl-CoA hydrolase (6-OCH-CoA hydrolase) (EC 3.7.1.21) (6-oxocyclohex-1-ene-1-carbonyl-CoA hydratase) (Q2LXU2)
Organism: Syntrophus aciditrophicus (strain SB)
Function: Involved in the central benzoyl-CoA catabolism. Catalyzes the addition of one molecule of water to the double bond and the hydrolytic cleavage of C-C bond in the alicyclic ring, 6-oxocyclohex-1-ene-1-carbonyl-CoA (6-OCH-CoA) to yield 3-hydroxypimelyl-CoA.
Sequence: MSLDWMPREHGLKNHSRHTEQWWGTEAPCTVYEKRPLKDPKGNVVPGLYSAWIRLNNPGQYNSYTTEMVKGVIAGFENSSTDREVVAVVFTGTGPNAFCTGGNTKEYSEYYSMRPEEYGSYMELFNNMVDSILMCKKPVICRVNGMRVAGGQEIGTATDITVSSDLAIFGQAGPRHGSAPVGGASDFLPWFLSIEDAMWNCVSCEMWSAYKMKAKNLISKALPVLKDDKGNWVRNPQVYTDTYVKDGEIVYGEPKTGEEAKQARAWVNEKLKNNDYDFSLIDAEVDRIVWVFANLFPGCLMKSIDGIRQKKKFWWDQIKNDHRYWLGTNMMGEAFLGFGAFNTKKITGKDTIDFIKNRQLIAEGALVDEAFMEQVLGKPLAK
InterPro domains: - IPR029045: ClpP/crotonase-like domain superfamily (homologous_superfamily) [51-344]
- IPR017613: 6-oxocyclohex-1-ene-1-carbonyl-CoA hydrolase (family) [13-376]
- IPR001753: Enoyl-CoA hydratase/isomerase (family) [52-224]
Interaction partners: - 6-hydroxycyclohex-1-ene-1-carboxyl-CoA dehydrogenase
- propanoyl-CoA C-acyltransferase
- Acetyl-CoA acetyltransferase
- histidine kinase
- 4Fe-4S protein
- 4Fe-4S protein
- 4Fe-4S protein
- Ferredoxin
- Aldehyde dehydrogenase
- Aldehyde dehydrogenase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0044248 (cellular catabolic process), GO:0019637 (organophosphate metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:1901575 (organic substance catabolic process), GO:0006790 (sulfur compound metabolic process), GO:0035383 (thioester metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0006793 (phosphorus metabolic process), GO:0034655 (nucleobase-containing compound catabolic process), GO:0044270 (cellular nitrogen compound catabolic process), GO:0006753 (nucleoside phosphate metabolic process), GO:0044273 (sulfur compound catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0006637 (acyl-CoA metabolic process), GO:1901136 (carbohydrate derivative catabolic process), GO:0019693 (ribose phosphate metabolic process), GO:0019439 (aromatic compound catabolic process), GO:1901361 (organic cyclic compound catabolic process), GO:0046700 (heterocycle catabolic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0072521 (purine-containing compound metabolic process), GO:0046434 (organophosphate catabolic process), GO:0009261 (ribonucleotide catabolic process), GO:0009259 (ribonucleotide metabolic process), GO:0072523 (purine-containing compound catabolic process), GO:1901292 (nucleoside phosphate catabolic process), GO:0009117 (nucleotide metabolic process), GO:0006163 (purine nucleotide metabolic process), GO:0034032 (purine nucleoside bisphosphate metabolic process), GO:0033865 (nucleoside bisphosphate metabolic process), GO:0034034 (purine nucleoside bisphosphate catabolic process), GO:0009154 (purine ribonucleotide catabolic process), GO:0009150 (purine ribonucleotide metabolic process), GO:0033869 (nucleoside bisphosphate catabolic process), GO:0009166 (nucleotide catabolic process), GO:0006195 (purine nucleotide catabolic process), GO:0033875 (ribonucleoside bisphosphate metabolic process), GO:0034031 (ribonucleoside bisphosphate catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)