Protein: Geranylgeranyl diphosphate reductase, chloroplastic (EC 1.3.1.83) (Geranylgeranyl reductase) (Q9ZS34)
Organism: Nicotiana tabacum (Common tobacco)
Function: Catalyzes the reduction of geranylgeranyl diphosphate to phytyl diphosphate, providing phytol for both tocopherol and chlorophyll synthesis.
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Sequence: MASIALKTFTGLRQSSPENNSITLSKSLPFTQTHRRLRINASKSSPRVNGRNLRVAVVGGGPAGGAAAETLAKGGIETFLIERKMDNCKPCGGAIPLCMVGEFDLPLDIIDRKVTKMKMISPSNVAVDIGQTLKPHEYIGMVRREVLDAYLRDRAAEAGASVLNGLFLKMDMPKAPNAPYVLHYTAYDSKTNGAGEKRTLEVDAVIGADGANSRVAKSINAGDYEYAIAFQERIKISDDKMKYYENLAEMYVGDDVSPDFYGWVFPKCDHVAVGTGTVTHKADIKKFQLATRLRADSKITGGKIIRVEAHPIPEHPRPRRLQDRVALVGDAAGYVTKCSGEGIYFAAKSGRMCAEAIVEGSEMGKRMVDESDLRKYLEKWDKTYWPTYKVLDILQKVFYRSNPAREAFVEMCADEYVQKMTFDSYLYKKVAPGNPIEDLKLAVNTIGSLVRANALRREMDKLSV
InterPro domains: - IPR050407: Geranylgeranyl Reductase (family) [51-457]
- IPR002938: FAD-binding domain (domain) [54-86]
- IPR011774: Geranylgeranyl reductase, plant/cyanobacteria (family) [53-451]
- IPR011777: Geranylgeranyl reductase family (family) [55-357]
- IPR036188: FAD/NAD(P)-binding domain superfamily (homologous_superfamily) [52-463]
- IPR010253: Geranylgeranyl reductase, plant/prokaryotic (family) [54-451]
Interaction partners: - magnesium-protoporphyrin IX monomethyl ester
- Prolycopene isomerase, chloroplastic-like.
- Prolycopene isomerase, chloroplastic-like.
- Magnesium-chelatase subunit ChlI, chloroplastic
- Mg-protoporphyrin IX chelatase
- Electron transfer flavoprotein subunit beta
- Electron transfer flavoprotein subunit beta
- Homogentisate geranylgeranyltransferase-like
- Homogentisate geranylgeranyltransferase-like
- Magnesium-chelatase subunit ChlH
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016627 (oxidoreductase activity, acting on the CH-CH group of donors), GO:0016628 (oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0006082 (organic acid metabolic process), GO:0006631 (fatty acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0016053 (organic acid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0006633 (fatty acid biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process), GO:0072330 (monocarboxylic acid biosynthetic process), GO:0032787 (monocarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle)