wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Amino acid permease 5 (Amino acid transporter AAP5) (Q8GUM3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Amino acid-proton symporter. Stereospecific transporter with a broad specificity for glutamate and both neutral and basic amino acids. Reduced affinities for asparagine and valine. High affinity transport of the cationic amino acids arginine and lysine, but not of histidine.
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Sequence: MVVQNVQDLDVLPKHSSDSFDDDGRPKRTGTVWTASAHIITAVIGSGVLSLAWAVAQIGWIGGPVAMLLFSFVTFYTSTLLCSCYRSGDSVTGKRNYTYMDAIHSNLGGIKVKVCGVVQYVNLFGTAIGYTIASAISLVAIQRTSCQQMNGPNDPCHVNGNVYMIAFGIVQIIFSQIPDFDQLWWLSIVAAVMSFAYSAIGLGLGVSKVVENKEIKGSLTGVTVGTVTLSGTVTSSQKIWRTFQSLGNIAFAYSYSMILIEIQDTVKSPPAEVNTMRKATFVSVAVTTVFYMLCGCVGYAAFGDNAPGNLLAHGGFRNPYWLLDIANLAIVIHLVGAYQVYCQPLFAFVEKEASRRFPESEFVTKEIKIQLFPGKPFNLNLFRLVWRTFFVMTTTLISMLMPFFNDVVGLLGAIGFWPLTVYFPVEMYIAQKNVPRWGTKWVCLQVLSVTCLFVSVAAAAGSVIGIVSDLKVYKPFQSEF
InterPro domains: - IPR013057: Amino acid transporter, transmembrane domain (domain) [28-467]
Interaction partners: - Cationic amino acid transporter 6
- WAT1-related protein At4g01430
- WAT1-related protein At1g01070
- WAT1-related protein At2g39510
- WAT1-related protein At1g44800
- Cationic amino acid transporter 8
- WAT1-related protein At1g25270
- WAT1-related protein At2g40900
- Cationic amino acid transporter 9
- WAT1-related protein At1g09380
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity), GO:0005342 (organic acid transmembrane transporter activity), GO:0046943 (carboxylic acid transmembrane transporter activity), GO:0015171 (amino acid transmembrane transporter activity), GO:0015172 (acidic amino acid transmembrane transporter activity), GO:0015175 (neutral L-amino acid transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:0006865 (amino acid transport), GO:0015849 (organic acid transport), GO:0015711 (organic anion transport), GO:0046942 (carboxylic acid transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Glucose-fructose oxidoreductase domain-containing protein 1 (Gfo/Idh/MocA-like oxidoreductase domain-containing protein 1) (Q9NXC2)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Secreted {ECO:0000305}.
Sequence: MLPGVGVFGTSLTARVIIPLLKDEGFAVKALWGRTQEEAEELAKEMSVPFYTSRIDEVLLHQDVDLVCINLPPPLTRQIAVKTLGIGKNVICDRTATPLDAFRMTSAAHYYPKLMSIMGNVLRFLPAFVRMKQLIEEGYVGEPLVCEVQVHGGSLLGKKYNWSCDDLMGGGGLHSVGTYIIDLLTFLTGQKAVKVHGLLKTFVKQTDHIKGIRQITSDDFCTFQMVLEGGVCCTVTLNFNVPGEFKQDVTVVGSAGRLLAVGTDLYGQRNSAPEQELLVQDATPVSNSLLPEKAFSDIPSPYLRGTIKMMQAVRQAFQDQDDRRTWDGRPLTMAATFDDCLYALCVVDTIKRSSQTGEWQNIAIMTEEPELSPAYLISEAMRRSRMSLYC
InterPro domains: - IPR050463: Gfo/Idh/MocA family oxidoreductases and glycosidases (family) [2-368]
- IPR000683: Gfo/Idh/MocA-like oxidoreductase, N-terminal (domain) [5-109]
- IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [4-148]
- IPR055170: GFO/IDH/MocA-like oxidoreductase domain (domain) [128-258]
Interaction partners: - NF-kappa-B inhibitor-interacting Ras-like protein 2
- Glucose-fructose oxidoreductase domain-containing protein 2
- Ral GTPase-activating protein subunit alpha-2
- Putative keratin-associated protein 20-4
- dTDP-D-glucose 4,6-dehydratase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0045229 (external encapsulating structure organization), GO:0043062 (extracellular structure organization), GO:0030198 (extracellular matrix organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005615 (extracellular space), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0005576 (extracellular region), GO:0070062 (extracellular exosome), GO:0043227 (membrane-bounded organelle), GO:0043230 (extracellular organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:1903561 (extracellular vesicle)
Protein: Predicted gene 4924 (A0A1B0GR71)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MDLVTYEDVHVNFTQEEWALLDPSQKSLYKDVMLETYRNLTAIGYKWEDFNIEEHCKCPKRHERYIICHSGFKPCEDKQYKKKQCTLVSPRTIRQCVVVPTMRRHDDCDTDLQLTGFLTSMAAHHQTNTGEKPYEYKEYRNSSVYTGSLCTCHVAHKIGKYYAYNQCDKTLSSSSSLLGCEKILVGKGSDKSEPCTKGFNHHRYLQTHKRTNSEDLYEYNQHDKDFRSNSSVKLHERTHLEIELYEDNQSEKAFATHSLHQVPRSHTREERYGYDQCGNTFACLSYLQIHERISLEKPFECNQCSKAFAYKRHLHRHEKIHTGEKPYGCNQCGKAFVYNSYLQRHKRSHTGEKPYECHQCGKAFSRNSHLYRHERSHTGEKPYGCNKCGKAFGRNSTLQRHERSHNGEKPYGCNKCGKAFGRNSTLQRHERSHNGEKPYERKQCDKAFAQNSHLFHHEVNCTQEKSYGCSQCGKAFAYNSLLQRHERSHTGEKPYECNKCGKAFSQNSHLHKHERSHTGEKPYGRKQCDKAFAQNSHLFHHEINCTQEKSYGCSQCGKAFAYNSHLQRHERSHTGEKPYECNKCGKAFSQNSHLHKHERSHTGEKPYGRKQCDKAFAQNSHLFHHEINCTQEKSYGCSQCGKAFAYNSQLQRHERSHTGEKPYECNKCGKAFGHYSNLQRHERNHTGEKPYECKKCGKAFSQNSHLHKHERSHTEEKPYGRKQCDKDFAQKNLLHSHERNLSGQKPCEYNQSGKAFAQNSHLFHHEIDHTQEKSYGCSQCGKAFAYNSQLQRHERSHTGEKPYGCNKCGKAFAQKNNLHSHERSHTGEKPYECKKCGKAFSQNSHLHKHERSHTGEKPYGRKQCDKAFAQNSHLFHHEINCTQEKSYGCSQCGKAFGRYSNLQRHERSHTGEKPYECNKCGKAFSQNSHLHKHERSHTGEKPYECNQCLKAFACKSNLYRHERRHT
InterPro domains: - IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [160-965]
- IPR036051: Krueppel-associated box domain superfamily (homologous_superfamily) [2-57]
- IPR050758: Zinc finger protein, C2H2-type (family) [2-392]
- IPR013087: Zinc finger C2H2-type (domain) [299-966]
- IPR001909: Krueppel-associated box (domain) [3-77]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0009408 (response to heat), GO:0009266 (response to temperature stimulus), GO:0033554 (cellular response to stress), GO:0034605 (cellular response to heat)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH) (O13696)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Performs an essential role in the oxidative function of the citric acid cycle. Also binds RNA; specifically to the 5'-untranslated leaders of mitochondrial mRNAs.
Subcellular location: Mitochondrion {ECO:0000250}.
Sequence: MFKSLVRKSSAFQPLKYGGKYTVTLIPGDGIGRETSNAVTEIFKTANVPIEFEEIDVTGMEKNNKSSGDALHEAIQSLKRNKVGLKGILFTPFEKGGHTSFNVALRKELDIYASLVLIKNIPGFKTRHDNVDFAIIRENTEGEYSGLEHQSVPGVVESLKIITEYKSKRIAQFAFDFALQNGRKSVTCIHKANIMKLADGLFRRTFYDVANGYDAITPKDLIVDNASMQAVSRPQQFDVLVMPNLYGSILSNIGSALVGGPGVIPGANFGRDYALFEPGCRHVGLSITGRGEANPTAAILSACLMLRHLGLKDYADLINAATYSVIEEGKTLTKDLGGSASTGDFTHAILERMESL
InterPro domains: - IPR019818: Isocitrate/isopropylmalate dehydrogenase, conserved site (conserved_site) [244-263]
- IPR004434: Isocitrate dehydrogenase NAD-dependent (family) [18-353]
- IPR024084: Isopropylmalate dehydrogenase-like domain (domain) [22-349]
Interaction partners: - Isocitrate dehydrogenase subunit 2, mitochondrial
- Aconitate hydratase, mitochondrial
- Probable isocitrate dehydrogenase, mitochondrial
- 2-oxoglutarate dehydrogenase, mitochondrial
- Homoisocitrate dehydrogenase
- Aspartate aminotransferase, mitochondrial
- Glutamate synthase
- Probable citrate synthase, mitochondrial
- Probable NAD-specific glutamate dehydrogenase
- NADP-specific glutamate dehydrogenase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor), GO:0004448 (isocitrate dehydrogenase [NAD(P)+] activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006091 (generation of precursor metabolites and energy), GO:0015980 (energy derivation by oxidation of organic compounds), GO:0045333 (cellular respiration), GO:0009060 (aerobic respiration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Beta-adaptin-like protein (F4JXV9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004308}.
Sequence: MAPPAASQRYPSPSQPSGKSEVSDLKTQLRQLAGSRAPGVDDSKRDLYKKVISYMTIGIDVSSVFGEMVMCSATSDIVLKKMCYLYVGNYAKGNPDLSLLTINFLQRDCKDEDPMIRGLALRSLCSLRVPNLVEYLVGPLGSGLKDNNSYVRTIAVTGVLKLYHISPSTCIDADFPATLKSLMLHDSDAQVVANCLSALQEIWSLEASHSEEACREKESLLSKPVIYYFLNRIKEFNEWAQCLILELAVKYVPSDSNDIFDIMNLLEDRLQHANGAVVLATVKVFLQLTLSMTDVHQQVYERIKSPLLTLVSSGSPEQSYAILSHLHLLVVRAPFIFAADYKHFYCQYNEPSYVKKLKLEMLTAVANESNTYEIVTELCEYAANVDIAIARESIRAVGKIALQQYDVNAIVDRLLQFLEMEKDYVTAETLVLVKDLLRKYPQWSHDCISVVGGISSKNIQEPKAKAALIWMLGEYAQDMSDAPYVLENLIENWEEEHSAEVRLHLLTAAMKCFFKRAPETQKALGTALAAGIADFHQDVHDRALFYYRVLQYDVHVAERVVSPPKQAVSVFADTQSSEIKDRVFDEFNSLSVIYQKPSYMFTDKEHRGPFEFSDEVGNISITPEASSDIVPAQQYEANDKDLLLGIDEKDENKGVSNNNGSAYTAPSLESSSNITSQMQELAISGPATSATTPQSFGFDDLFGLGLSTAPAPTPSPPLLKLNARAALDPGAFQQKWRQLPISLTQECSVNPQGIAALTVPQSLIKHMQSHSIHCIASGGQSPNFKFFFFAQKESEPSNYLTECIINTSSAKAQIKVKADEQSTCQAFTTVFETALSKFVSLTFDFVSLCY
InterPro domains: - IPR016024: Armadillo-type fold (homologous_superfamily) [29-598]
- IPR012295: TBP domain superfamily (homologous_superfamily) [710-841]
- IPR026739: AP complex subunit beta (family) [20-806]
- IPR011989: Armadillo-like helical (homologous_superfamily) [14-608]
- IPR015151: Beta-adaptin appendage, C-terminal subdomain (domain) [719-836]
- IPR002553: Clathrin/coatomer adaptor, adaptin-like, N-terminal (domain) [39-551]
- IPR016342: AP-1/2/4 complex subunit beta (family) [11-841]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Type II NADH:quinone oxidoreductase NdhA (EC 1.6.5.9) (Type II NADH dehydrogenase NdhA) (P95200)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Alternative, nonproton pumping NADH:quinone oxidoreductase that delivers electrons to the respiratory chain by oxidation of NADH and reduction of quinones.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:15767566}; Single-pass membrane protein {ECO:0000255}.
Sequence: MTLSSGEPSAVGGRHRVVIIGSGFGGLNAAKALKRADVDITLISKTTTHLFQPLLYQVATGILSEGDIAPTTRLILRRQKNVRVLLGEVNAIDLKAQTVTSKLMDMTTVTPYDSLIVAAGAQQSYFGNDEFATFAPGMKTIDDALELRGRILGAFEAAEVSTDHAERERRLTFVVVGAGPTGVEVAGQIVELAERTLAGAFRTITPSECRVILLDAAPAVLPPMGPKLGLKAQRRLEKMDVEVQLNAMVTAVDYKGITIKEKDGGERRIECACKVWAAGVAASPLGKMIAEGSDGTEIDRAGRVIVEPDLTVKGHPNVFVVGDLMFVPGVPGVAQGAIQGARYATTVIKHMVKGNDDPANRKPFHYFNKGSMATISRHSAVAQVGKLEFAGYFAWLAWLVLHLVYLVGYRNRIAALFAWGISFMGRARGQMAITSQMIYARLVMTLMEQQAQGALAAAEQAEHAEQEAAG
InterPro domains: - IPR045024: Alternative NADH dehydrogenase (family) [13-424]
- IPR036188: FAD/NAD(P)-binding domain superfamily (homologous_superfamily) [14-348]
- IPR023753: FAD/NAD(P)-binding domain (domain) [16-340]
Interaction partners: - NADH-quinone oxidoreductase subunit A
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016651 (oxidoreductase activity, acting on NAD(P)H), GO:0016655 (oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor), GO:0003955 (NAD(P)H dehydrogenase (quinone) activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006091 (generation of precursor metabolites and energy), GO:0015980 (energy derivation by oxidation of organic compounds), GO:0022900 (electron transport chain), GO:0022904 (respiratory electron transport chain), GO:0045333 (cellular respiration), GO:0019646 (aerobic electron transport chain), GO:0009060 (aerobic respiration), GO:0006119 (oxidative phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Histone H2AX (H2a/x) (Histone H2A.X) (Q7ZUY3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P27661}. Chromosome {ECO:0000250|UniProtKB:P27661}.
Sequence: MSGRGKTGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTGQAAASSGKSGKKGSSQSQEY
InterPro domains: - IPR009072: Histone-fold (homologous_superfamily) [2-135]
- IPR002119: Histone H2A (family) [3-123]
- IPR007125: Histone H2A/H2B/H3 (domain) [9-89]
- IPR032454: Histone H2A, C-terminal domain (domain) [92-125]
- IPR032458: Histone H2A conserved site (conserved_site) [22-28]
Interaction partners: - Peptidyl-prolyl cis-trans isomerase
- Mediator of DNA damage checkpoint 1.
- Histone H2B 3
- Histone H2B
- non-specific serine/threonine protein kinase
- Histone H3.3
- Checkpoint kinase 2.
- DNA helicase
- E3 ubiquitin-protein ligase rnf168
- Histone H3.2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0002088 (lens development in camera-type eye), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0043010 (camera-type eye development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus), GO:0005694 (chromosome)
Protein: Uncharacterized protein Rv0502 (P9WKT1)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Not known
Sequence: MGNVAGETRANVIPLHTNRSRVAARRRAGQRAESRQHPSLLSDPNDRASAEQIAAVVREIDEHRRAAGATTSSTEATPNDLAQLVAAVAGFLRQRLTGDYSVDEFGFDPHFNSAIVRPLLRFFFKSWFRVEVSGVENIPRDGAALVVANHAGVLPFDGLMLSVAVHDEHPAHRDLRLLAADMVFDLPVIGEAARKAGHTMACTTDAHRLLASGELTAVFPEGYKGLGKRFEDRYRLQRFGRGGFVSAALRTKAPIVPCSIIGSEEIYPMLTDVKLLARLFGLPYFPITPLFPLAGPVGLVPLPSKWRIAFGEPICTADYASTDADDPMVTFELTDQVRETIQQTLYRLLAGRRNIFFG
InterPro domains: - IPR016676: Phospholipid/glycerol acyltransferase, predicted (family) [46-358]
- IPR002123: Phospholipid/glycerol acyltransferase (domain) [129-263]
Interaction partners: - Uncharacterized protein Rv0501
- Uncharacterized protein Rv0500B
- Conserved protein TB16.3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0008374 (O-acyltransferase activity), GO:0016411 (acylglycerol O-acyltransferase activity), GO:0004144 (diacylglycerol O-acyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:1903509 (liposaccharide metabolic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0046467 (membrane lipid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0006643 (membrane lipid metabolic process), GO:0009247 (glycolipid biosynthetic process), GO:0006664 (glycolipid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: trypsin (EC 3.4.21.4) (Q9VRS9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Secreted, extracellular space {ECO:0000256|ARBA:ARBA00004239}.
Sequence: MKVLAVLLLGVIASATAFEKPVFWKDVPVGKASIEGRITMGYPAYEGKVPYIVGLGFSKNGGGTWCGGSIIGNTWVMTAKHCTDGMESVTIYYGALWRLQAQYTHWVGRSDFIEHGSGDISLIRTPHVDFWSLVNKVELPRYDDRYNNYQGWWALVSGWGKTSDEGGVSEYLNCVDVQIGENSVCENYYGSFSGDLICIPTPENKGTCSGDSGGPLVIHDGNRQVGIVSFGSSAGCLSNGPKGMVRVTSYLDWIRDNTGISY
InterPro domains: - IPR001314: Peptidase S1A, chymotrypsin family (family) [67-217]
- IPR043504: Peptidase S1, PA clan, chymotrypsin-like fold (homologous_superfamily) [47-255]
- IPR033116: Serine proteases, trypsin family, serine active site (active_site) [206-217]
- IPR050430: Peptidase S1 family serine proteases (family) [1-259]
- IPR009003: Peptidase S1, PA clan (homologous_superfamily) [1-259]
- IPR001254: Serine proteases, trypsin domain (domain) [37-259]
Interaction partners: - Jonah 25Biii
- Jonah 65Aii
- Peptidase S1 domain-containing protein
- Jonah 25Bii, isoform A
- Jonah 44E, isoform A
- Serine protease 3
- trypsin
- Zinc carboxypeptidase A 1
- Jonah 99Fii
- trypsin
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0017171 (serine hydrolase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0019953 (sexual reproduction), GO:0065008 (regulation of biological quality), GO:0019098 (reproductive behavior), GO:0044706 (multi-multicellular organism process), GO:0071704 (organic substance metabolic process), GO:0032504 (multicellular organism reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0044238 (primary metabolic process), GO:0007610 (behavior), GO:0006807 (nitrogen compound metabolic process), GO:0044703 (multi-organism reproductive process), GO:0046692 (sperm competition), GO:0045924 (regulation of female receptivity), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0007320 (insemination), GO:0007617 (mating behavior), GO:0043170 (macromolecule metabolic process), GO:0060180 (female mating behavior), GO:0051604 (protein maturation), GO:0006508 (proteolysis), GO:0007620 (copulation), GO:0046008 (regulation of female receptivity, post-mating), GO:0010467 (gene expression), GO:0016485 (protein processing), GO:0031638 (zymogen activation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein (Q9SHA0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MKCCKFVAVALMSLLISLASVEAAGECGRMPINQAAASLSPCLPATKNPRGKVPPVCCAKVGALIRTNPRCLCAVMLSPLAKKAGINPGIAIGVPKRCNIRNRPAGKRCGRYIVP
InterPro domains: - IPR039265: Putative lipid-transfer protein DIR1-like (family) [7-109]
- IPR000528: Plant non-specific lipid-transfer protein/Par allergen (family) [31-102]
- IPR016140: Bifunctional inhibitor/plant lipid transfer protein/seed storage helical domain (domain) [19-109]
- IPR036312: Bifunctional inhibitor/plant lipid transfer protein/seed storage helical domain superfamily (homologous_superfamily) [27-105]
Interaction partners: - Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein
- At4g33550
- Protein TEEBE
- Jacalin-related lectin 20
- Non-specific lipid transfer protein GPI-anchored 7
- Phosphatidylinositol:ceramide inositolphosphotransferase 3
- Non-specific lipid transfer protein GPI-anchored 20
- 2S seed storage protein 5
- Phosphatidylinositol:ceramide inositolphosphotransferase 1
- Beta-glucosidase 22
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0008289 (lipid binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:0002239 (response to oomycetes), GO:0043207 (response to external biotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle)