wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: PPE family protein PPE32 (P9WI05)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Virulence factor that modulates the production of host cytokines. Interacts with host TLR2 receptor at the macrophage cell surface and induces the secretion of the anti- inflammatory cytokine interleukin-10 (IL-10) and the pro-inflammatory cytokines TNF-alpha and interleukin-6 (IL-6), via coactivation of MAPK and NF-kappa-B signaling pathways. Also increases the expression of IL-12p40 and IL-32 through activation of the ERK1/2 signaling pathway. Can induce cell apotopsis in macrophages via activation of caspases and increase reticulum endoplasmic stress response. When expressed in M.smegmatis, it enhances M.smegmatis survival within host macrophages and slightly accelerates cell death of infected macrophages
Subcellular location: Secreted, cell wall. Cell surface
Sequence: MLDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGPSSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSLVATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATAAQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTILANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGALFGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD
InterPro domains: - IPR022171: PPE family, C-terminal (domain) [313-383]
- IPR000030: PPE domain (domain) [3-165]
- IPR038332: PPE superfamily (homologous_superfamily) [2-175]
Interaction partners: - Uncharacterized PPE family protein PPE33
- Uncharacterized PPE family protein PPE33
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005618 (cell wall), GO:0009274 (peptidoglycan-based cell wall)
Protein: Uncharacterized PPE family protein PPE33 (P9WI03)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Sequence: MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGPSSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISLVATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTAPPQTTNPSGLAGQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQLMGQLINAIFGPTGATTYQNVFVTAANVTKFSTWANDAMSAPNLGMTEFKVFWQPPPAPEIPKSSLGAGLGLRSGLSAGLAHAASAGLGQANLVGDLSVPPSWASATPAVRLVANTLPATSLAAAPATQIPANLLGQMALGSMTGGALGAAAPAIYTGSGARARANGGTPSAEPVKLEAVIAQLQKQPDAVRHWNVDKADLDGLLDRLSKQPGIHAVHVSNGDKPKVALPDTQLGSH
InterPro domains: - IPR022171: PPE family, C-terminal (domain) [316-384]
- IPR000030: PPE domain (domain) [2-165]
- IPR038332: PPE superfamily (homologous_superfamily) [1-174]
Interaction partners: - PPE family protein PPE32
- PPE family protein PPE32
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Transporter PPE51 (P9WHY3)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Small molecule-selective channel required for the uptake of nutrients across the outer mycomembrane. Transports glycerol and glucose. Involved in sensitivity to M.tuberculosis growth inhibitory agrichemical 3,3-bis- di(methylsulfonyl)propionamide (3bMP1). Transports maltose and lactose disaccharides. Involved in sensitivity to bactericidal thio-disaccharide T-6 compound (1,6-anhydro-3-deoxy-4-S- (2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)-D-glycero-hexopyranos-2- ulose). Transports extracellular trehalose, a component of the cell envelope, and trehalose analog, 6-azido trehalose (6-TreAz), which has antimycobacterial activity
Subcellular location: Cell outer membrane
Sequence: MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGPAAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLALIATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLTAQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG
InterPro domains: - IPR022171: PPE family, C-terminal (domain) [300-376]
- IPR000030: PPE domain (domain) [2-164]
- IPR038332: PPE superfamily (homologous_superfamily) [1-174]
Interaction partners: - Uncharacterized PPE family protein PPE50
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005618 (cell wall), GO:0009274 (peptidoglycan-based cell wall)
Protein: Uncharacterized PPE family protein PPE65 (P9WHX3)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Sequence: MLDFAQLPPEVNSALMYAGPGSGPMLAAAAAWEALAAELQTTASTYDALITGLADGPWQGSSAASMVAAATPQVAWLRSTAGQAEQAGSQAVAAASAYEAAFFATVPPPEIAANRALLMALLATNFLGQNTAAIAATEAQYAEMWAQDAAAMYGYAGASAAATQLSPFNPAAQTINPAGLASQAASVGQAVSGAANAQALTDIPKALFGLSGIFTNEPPWLTDLGKALGLTGHTWSSDGSGLIVGGVLGDFVQGVTGSAELDASVAMDTFGKWVSPARLMVTQFKDYFGLAHDLPKWASEGAKAAGEAAKALPAAVPAIPSAGLSGVAGAVGQAASVGGLKVPAVWTATTPAASPAVLAASNGLGAAAAAEGSTHAFGGMPLMGSGAGRAFNNFAAPRYGFKPTVIAQPPAGG
InterPro domains: - IPR022171: PPE family, C-terminal (domain) [329-409]
- IPR000030: PPE domain (domain) [3-165]
- IPR038332: PPE superfamily (homologous_superfamily) [2-175]
Interaction partners: - PE family protein PE32
- Probable carbon monoxyde dehydrogenase (Large chain)
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005618 (cell wall), GO:0009274 (peptidoglycan-based cell wall)
Protein: Pickpocket protein 19 (Q9VAJ3)
Organism: Drosophila melanogaster (Fruit fly)
Function: Part of a complex that plays a role in tracheal liquid clearance. In both larvae and adults, contributes to the behavioral response to salt. Probable role in sodium transport
Subcellular location: Membrane; Multi-pass membrane protein
Sequence: MLLYTKELVIPRPRPGLLRFRNNPRGIKFREKLCNSFAHSNIHGMQHVFGEQHLWQRCLWLAIVLGAVITGFSLYTVLMHRHSEQLLVSLIETTQLPVYHIDFPAVAVCPWNHFNWQRAPSAFIRFLPRHPNAELRETFRQLLASMDIMNFSNFNRIRILTKRNLTGISYLKMTDLMNFMTYRCDELFVADSCVFDETPYDCCKLFVREQTVKGQCLVFNSMISENSRKKHLINQFYPHKLSTAGEDSGLKFTINASYSFMNNIDALTPFGMNLMIKEPRQWSNEMMYHLYPDTENFVAVHPLVTETSPNTYEMSPKKRRCYFDDEKNPTFQNTSLTYNRENCLVVCLHLVVWKTCQCSLPAFLPPIDGVPECGINDAQCLGNNSDIFTYVKMGDQEKYINDSRQGHFCDCPDNCNSRLYEMSLNVRKLDYPKNSTDQLIKAQVYYGQRVMTKIITKLKYTNIDLLANFGGIISLYIGASVMSFIELLFVLGKLMWGFIRDARIKLKEYTK
InterPro domains: - IPR001873: Epithelial sodium channel (family) [34-492]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0015267 (channel activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0015081 (sodium ion transmembrane transporter activity), GO:0005261 (monoatomic cation channel activity), GO:0005272 (sodium channel activity), GO:0022839 (monoatomic ion gated channel activity), GO:0022836 (gated channel activity), GO:0046873 (metal ion transmembrane transporter activity), GO:0015280 (ligand-gated sodium channel activity), GO:0099094 (ligand-gated monoatomic cation channel activity), GO:0022834 (ligand-gated channel activity), GO:0015276 (ligand-gated monoatomic ion channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0032504 (multicellular organism reproduction), GO:0042221 (response to chemical), GO:0019098 (reproductive behavior), GO:0007610 (behavior), GO:0007617 (mating behavior), GO:0010033 (response to organic substance), GO:0060179 (male mating behavior), GO:0019236 (response to pheromone), GO:0007619 (courtship behavior), GO:0008049 (male courtship behavior)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)
Protein: Protein preY, mitochondrial (Q96I23)
Organism: Homo sapiens (Human)
Function: In mitochondria, S-adenosylmethionine-dependent methyltransferase chaperone that supports both coenzyme Q biosynthesis, by stabilizing its components, such as COQ5, and NADH:ubiquinone oxidoreductase complex (complex I, MT-ND1) assembly, by stabilizing complex I assembly factors, such as NDUFAF5
Subcellular location: Mitochondrion
Sequence: MLSGARCRLASALRGTRAPPSAVARRCLHASGSRPLADRGKKTEEPPRDFDPALLEFLVCPLSKKPLRYEASTNELINEELGIAYPIIDGIPNMIPQAARMTRQSKKQEEVEQR
InterPro domains: - IPR005651: Trm112-like (family) [50-103]
Interaction partners: - Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit P
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit H
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit C
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit A
- Dolichol phosphate-mannose biosynthesis regulatory protein
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0016043 (cellular component organization), GO:1901564 (organonitrogen compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0006790 (sulfur compound metabolic process), GO:0051604 (protein maturation), GO:0016226 (iron-sulfur cluster assembly), GO:0010467 (gene expression), GO:0022607 (cellular component assembly), GO:0097428 (protein maturation by iron-sulfur cluster transfer), GO:0031163 (metallo-sulfur cluster assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0031090 (organelle membrane), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098827 (endoplasmic reticulum subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0005789 (endoplasmic reticulum membrane)
Protein: Profilin-1 (P49230)
Organism: Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM)
Function: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG
Subcellular location: Cytoplasm, cytoskeleton. Cell projection, phagocytic cup. Cytoplasmic vesicle, phagosome. Note=Localizes to phagocytic cups and to phagosomes after their separation from the cell membrane
Sequence: MSWQSYVDSFLVGAGKGMGGAIIGLQGGVWAASANCTPSAQESVAIGTACASNIAGLQQTGVVIGGKKYMITRVDADEGTAMGKKGAEGISIYKTKQAVIIGYFSDASVSAGQNSDATYKCAKYLMDAGY
InterPro domains: - IPR036140: Profilin superfamily (homologous_superfamily) [2-130]
- IPR027310: Profilin conserved site (conserved_site) [1-8]
- IPR005455: Profilin, eukaryotic type (family) [1-130]
- IPR048278: Profilin (family) [1-130]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0003779 (actin binding), GO:0003785 (actin monomer binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0022607 (cellular component assembly), GO:0043933 (protein-containing complex organization), GO:0065003 (protein-containing complex assembly), GO:0051259 (protein complex oligomerization), GO:0051260 (protein homooligomerization), GO:0051262 (protein tetramerization), GO:0051289 (protein homotetramerization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0043229 (intracellular organelle), GO:0005938 (cell cortex), GO:0043228 (non-membrane-bounded organelle), GO:0030863 (cortical cytoskeleton), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0030864 (cortical actin cytoskeleton), GO:0015629 (actin cytoskeleton)
Protein: PTS system galactitol-specific EIIC component (P69831)
Organism: Escherichia coli (strain K12)
Function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. The enzyme II complex composed of GatA, GatB and GatC is involved in galactitol transport
Subcellular location: Cell inner membrane; Multi-pass membrane protein
Sequence: MFSEVMRYILDLGPTVMLPIVIIIFSKILGMKAGDCFKAGLHIGIGFVGIGLVIGLMLDSIGPAAKAMAENFDLNLHVVDVGWPGSSPMTWASQIALVAIPIAILVNVAMLLTRMTRVVNVDIWNIWHMTFTGALLHLATGSWMIGMAGVVIHAAFVYKLGDWFARDTRNFFELEGIAIPHGTSAYMGPIAVLVDAIIEKIPGVNRIKFSADDIQRKFGPFGEPVTVGFVMGLIIGILAGYDVKGVLQLAVKTAAVMLLMPRVIKPIMDGLTPIAKQARSRLQAKFGGQEFLIGLDPALLLGHTAVVSASLIFIPLTILIAVCVPGNQVLPFGDLATIGFFVAMAVAVHRGNLFRTLISGVIIMSITLWIATQTIGLHTQLAANAGALKAGGMVASMDQGGSPITWLLIQVFSPQNIPGFIIIGAIYLTGIFMTWRRARGFIKQEKVVLAE
InterPro domains: - IPR013014: Phosphotransferase system, EIIC component, type 2 (domain) [6-435]
- IPR004703: Phosphotransferase system, sugar-specific permease component (family) [8-386]
- IPR013853: Galactitol permease IIC component (family) [1-445]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0022803 (passive transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0015267 (channel activity), GO:0015291 (secondary active transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0098739 (import across plasma membrane), GO:0034219 (carbohydrate transmembrane transport), GO:0006810 (transport), GO:0098704 (carbohydrate import across plasma membrane), GO:0015749 (monosaccharide transmembrane transport), GO:0071702 (organic substance transport), GO:0098657 (import into cell), GO:0008645 (hexose transmembrane transport), GO:0009401 (phosphoenolpyruvate-dependent sugar phosphotransferase system), GO:0008643 (carbohydrate transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Orotidine 5'-phosphate decarboxylase (P13649)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Sequence: MTVNTKTYSERAETHASPVAQRLFRLMESKKTNLCASIDVDTTKEFLELIDKLGPYVCLIKTHIDIINDFSYESTIEPLLGLSRKHQFMIFEDRKFADIGNTVKKQYIGGVYKISSWADITNAHGVTGNGVVEGLKQGAKETTTNQEPRGLLMLAELSSVGSLAYGEYSQKTVEIAKSDKEFVVGFIAQRDMGGQEEGFDWLIMTPGVGLDDKGDGLGQQYRTVDEVVSTGTDIIIVGRGLFGKGRDPDIEGKRYRDAGWNAYLKKTGQL
InterPro domains: - IPR014732: Orotidine 5'-phosphate decarboxylase (family) [5-268]
- IPR001754: Orotidine 5'-phosphate decarboxylase domain (domain) [32-255]
- IPR011060: Ribulose-phosphate binding barrel (homologous_superfamily) [5-266]
- IPR018089: Orotidine 5'-phosphate decarboxylase, active site (active_site) [90-103]
- IPR013785: Aldolase-type TIM barrel (homologous_superfamily) [3-270]
Interaction partners: - orotate phosphoribosyltransferase
- Uridylate kinase
- Phosphoribosylaminoimidazole carboxylase
- 3-isopropylmalate dehydrogenase
- Dihydroorotate dehydrogenase (quinone), mitochondrial
- Uridine kinase
- Imidazoleglycerol-phosphate dehydratase
- uracil phosphoribosyltransferase
- Argininosuccinate lyase
- N-(5'-phosphoribosyl)anthranilate isomerase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016830 (carbon-carbon lyase activity), GO:0016831 (carboxy-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0009112 (nucleobase metabolic process), GO:0018130 (heterocycle biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0072527 (pyrimidine-containing compound metabolic process), GO:0046112 (nucleobase biosynthetic process), GO:0006206 (pyrimidine nucleobase metabolic process), GO:0072528 (pyrimidine-containing compound biosynthetic process), GO:0019856 (pyrimidine nucleobase biosynthetic process), GO:0006207 ('de novo' pyrimidine nucleobase biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062039 (biofilm matrix), GO:0062040 (fungal biofilm matrix)