Protein: Protein POLLEN DEFECTIVE IN GUIDANCE 1 (F4HVJ3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable component of the calreticulin 3 (CRT3) complex, acting probably as a co-chaperone involved in protein retention in the endoplasmic reticulum lumen. Required for micropylar pollen tube guidance. Plays an essential role in cell plate orientation or positioning in early embryo patterning.
Subcellular location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Endoplasmic reticulum lumen {ECO:0000269|PubMed:21954464}. Note=Exclusive ER lumen localization and no membrane localization in PubMed:21954464.
Sequence: MAIRSSGRKLSFEILSQNSSFENDDTSIRRSSSDPITGNVASESPRDYGKRKRSKKKKKKVNQVETILENGDSHSTIITGSSGDFGETTTMFENRLNYYGGGGSGSSGGGCVVTLLDGQTVHHNGFNFGELRQRNVNGSVDGSNDERWSDTLSSDKKLYMEETSVELSPSENPPFQEVQHQFPRSEINGNVVRRLDTEASLDWKQLVADDPDFLSAETRSPMKYFMEEIYGGISLRSTTTPGNDIERERIYDTIFRLPWRCEVLIDTGFFVCVNSFLSLLTVMPIRVLLIFMDAFKNRQFRRPSASELSDLACFLVLATGTILLGRTDISLIYHMIRGQSTIKLYVVYNILEIFDRLCQSFCGDVFGALFSSAKGLSISPPEKLRFSTWRFVSDLALTMAASILHSFILLAQAITLSTCIVAHNNALLALLVSNNFAEIKSSVFKRFSKDNIHGLVYADSIERFHISAFLVSVLAQNILESEGAWFGNFIYNATTVFFCEMMIDIIKHSFLAKFNDIKPIAYSEFLQALCEQTLNIRPEDRKTNLTFVPLAPACVVIRVLTPVYAAHLPYSPLPWRMLWMVILFVITYIMLTSLKVLIGMGLRKHATWYINRCRRRNSSHLHND
InterPro domains: - IPR008010: Tapt1 family (family) [29-617]
Interaction partners: - Protein NUCLEAR FUSION DEFECTIVE 4
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051234 (establishment of localization), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0006950 (response to stress), GO:0032879 (regulation of localization), GO:0009266 (response to temperature stimulus), GO:0016043 (cellular component organization), GO:0051049 (regulation of transport), GO:0009409 (response to cold), GO:0033554 (cellular response to stress), GO:0006810 (transport), GO:0070417 (cellular response to cold), GO:0071702 (organic substance transport), GO:0006996 (organelle organization), GO:0010256 (endomembrane system organization), GO:0006811 (monoatomic ion transport), GO:0006643 (membrane lipid metabolic process), GO:0007029 (endoplasmic reticulum organization), GO:0006812 (monoatomic cation transport), GO:0006816 (calcium ion transport), GO:0007029 (endoplasmic reticulum organization), GO:0030001 (metal ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)