Protein: Dynein light chain Tctex-type 4 (Protein N22.1) (Tctex-2-beta) (Tctex1 domain-containing protein 4) (Q5JR98)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Cell projection, cilium, flagellum {ECO:0000269|PubMed:23789093}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:23789093}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:23789093}. Cytoplasm {ECO:0000250|UniProtKB:Q8CDY7}. Nucleus {ECO:0000250|UniProtKB:Q8CDY7}. Cytoplasm, cytoskeleton, microtubule organizing center {ECO:0000269|PubMed:23789093}. Note=Present along the entire length of the flagellum, including principal and endpiece, and more predominantly in the midpiece region. {ECO:0000269|PubMed:23789093}.
Sequence: MASRPLPPGRQEEENAKDSGRKPSPVRPRGCLPSIDEARPAGPGPAPASRRGSMLGLAASFSRRNSLVGPGAGPGGQRPSLGPVPPLGSRVSFSGLPLAPARWVAPSYRTEPVPGERWEAARAQRALEAALAAGLHDACYSSDEAARLVRELCEQVHVRLRELSPPRYKLVCSVVLGPRAGQGVHVVSRALWDVARDGLASVSYTNTSLFAVATVHGLYCE
InterPro domains: - IPR038586: Tctex-1-like superfamily (homologous_superfamily) [121-219]
- IPR005334: Dynein light chain Tctex-1 like (family) [104-221]
Interaction partners: - Dynein light chain Tctex-type 1
- Dynein light chain roadblock-type 2
- Dynein light chain Tctex-type protein 2B
- Dynein light chain roadblock-type 1
- Dynein light chain Tctex-type 3
- Cytoplasmic dynein 2 intermediate chain 1
- Cytoplasmic dynein 2 intermediate chain 2
- Cytoplasmic dynein 1 intermediate chain 1
- Cytoplasmic dynein 1 light intermediate chain 2
- Dynein light chain 2, cytoplasmic
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0050789 (regulation of biological process), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0071840 (cellular component organization or biogenesis), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0051649 (establishment of localization in cell), GO:0016043 (cellular component organization), GO:0051049 (regulation of transport), GO:0044085 (cellular component biogenesis), GO:0046907 (intracellular transport), GO:0060341 (regulation of cellular localization), GO:0006810 (transport), GO:0022607 (cellular component assembly), GO:0016192 (vesicle-mediated transport), GO:0030030 (cell projection organization), GO:0006996 (organelle organization), GO:0032386 (regulation of intracellular transport), GO:0070925 (organelle assembly), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0044782 (cilium organization), GO:0060271 (cilium assembly), GO:0120031 (plasma membrane bounded cell projection assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0005930 (axoneme), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0099568 (cytoplasmic region), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0005813 (centrosome), GO:0005929 (cilium), GO:0032838 (plasma membrane bounded cell projection cytoplasm), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0097014 (ciliary plasm), GO:0015630 (microtubule cytoskeleton)