Protein: Phospholipase A1-Ialpha2, chloroplastic (EC 3.1.1.-) (DAD1-like lipase 5) (Q9SIN9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acylhydrolase that catalyzes the hydrolysis of phosphatidylcholine at the sn-1 position. Has a strong galactolipase activity toward monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG). Low triacylglycerol (TAG) lipase activity. Plays a role in plant growth and in leaf senescence.
Subcellular location: Plastid, chloroplast, plastoglobule {ECO:0000269|PubMed:17259290, ECO:0000269|PubMed:19527719}.
Sequence: MALIQNPNMKHAPFLRNRSPQQTLFIPYTLSLPISYQNPKRLKTANSSSSSSLLAPVILNSPVASSSPPPIYCAPKFPCSSGAATVPLSRVWREIQGCNNWKDLIEPLNPLLQQEITRYGNLVSTCYKAFDLDPNSKRYLNCKYGKQTLLKETEIDQPEDYQVTKYIYATPDININISPIQNEMNRRARWVGYVAASSDDSVKRLGRRDIVVTFRGTVTNPEWLANFMSSLTPARFHPHNPRLDVKVESGFLSLYTSDESESKFGLESCRQQLLSEISRLMNKYKGEEMSITLAGHSMGSSLAQLLAYDIAELGLNRRIGKGDIPVTVFSFAGPRVGNLEFKKRCEELGVKVLRITNVNDPVTKLPGVLFNENFRVLGGFYELPWSCSCYVHVGVELTLDFFDVQNISCVHDLQTYIDLLNQRRTNSRSVDSDEDEDSDNVALEFLKTNGEKMMFLKRQRMMYWSNAVDLLFSFSNHMSYCNIF
InterPro domains: - IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [91-463]
- IPR002921: Fungal lipase-type domain (domain) [211-368]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0016298 (lipase activity), GO:0052689 (carboxylic ester hydrolase activity), GO:0008970 (phospholipase A1 activity), GO:0004620 (phospholipase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0009605 (response to external stimulus), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0009607 (response to biotic stimulus), GO:0050794 (regulation of cellular process), GO:0006950 (response to stress), GO:0045926 (negative regulation of growth), GO:0071704 (organic substance metabolic process), GO:0048523 (negative regulation of cellular process), GO:0051707 (response to other organism), GO:0040008 (regulation of growth), GO:0044238 (primary metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0043207 (response to external biotic stimulus), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0009611 (response to wounding), GO:0006082 (organic acid metabolic process), GO:0001558 (regulation of cell growth), GO:0030308 (negative regulation of cell growth), GO:0006952 (defense response), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0051128 (regulation of cellular component organization), GO:0009620 (response to fungus), GO:0098542 (defense response to other organism), GO:0006631 (fatty acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0016053 (organic acid biosynthetic process), GO:0050832 (defense response to fungus), GO:0008610 (lipid biosynthetic process), GO:0006633 (fatty acid biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0001676 (long-chain fatty acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process), GO:0072330 (monocarboxylic acid biosynthetic process), GO:0009694 (jasmonic acid metabolic process), GO:0042759 (long-chain fatty acid biosynthetic process), GO:0032787 (monocarboxylic acid metabolic process), GO:0009695 (jasmonic acid biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0043228 (non-membrane-bounded organelle), GO:0009507 (chloroplast), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005811 (lipid droplet)