wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Carotenoid-cleaving dioxygenase, mitochondrial (EC 1.13.11.-) (EC 1.13.11.71) (B-diox-II) (Beta,beta-carotene 9',10'-oxygenase) (Beta-carotene dioxygenase 2) (Q9BYV7)
Organism: Homo sapiens (Human)
Function: Broad specificity mitochondrial dioxygenase that mediates the asymmetric oxidative cleavage of carotenoids. Cleaves carotenes (pure hydrocarbon carotenoids) such as all-trans-beta-carotene and lycopene as well as xanthophylls (oxygenated carotenoids) such as zeaxanthin, lutein and beta-cryptoxanthin at both the 9,10 and the 9',10' carbon-carbon double bond. Through its function in carotenoids metabolism regulates oxidative stress and the production of important signaling molecules.
Subcellular location: Mitochondrion {ECO:0000250|UniProtKB:Q99NF1}.
Sequence: MFFRVFLHFIRSHSATAVDFLPVMVHRLPVFKRYMGNTPQKKAVFGQCRGLPCVAPLLTTVEEAPRGISARVWGHFPKWLNGSLLRIGPGKFEFGKDKYNHWFDGMALLHQFRMAKGTVTYRSKFLQSDTYKANSAKNRIVISEFGTLALPDPCKNVFERFMSRFELPGKAAAMTDNTNVNYVRYKGDYYLCTETNFMNKVDIETLEKTEKVDWSKFIAVNGATAHPHYDLDGTAYNMGNSFGPYGFSYKVIRVPPEKVDLGETIHGVQVICSIASTEKGKPSYYHSFGMTRNYIIFIEQPLKMNLWKIATSKIRGKAFSDGISWEPQCNTRFHVVEKRTGQLLPGRYYSKPFVTFHQINAFEDQGCVIIDLCCQDNGRTLEVYQLQNLRKAGEGLDQVHNSAAKSFPRRFVLPLNVSLNAPEGDNLSPLSYTSASAVKQADGTIWCSHENLHQEDLEKEGGIEFPQIYYDRFSGKKYHFFYGCGFRHLVGDSLIKVDVVNKTLKVWREDGFYPSEPVFVPAPGTNEEDGGVILSVVITPNQNESNFILVLDAKNFEELGRAEVPVQMPYGFHGTFIPI
InterPro domains: - IPR004294: Carotenoid oxygenase (family) [61-578]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0051213 (dioxygenase activity), GO:0016701 (oxidoreductase activity, acting on single donors with incorporation of molecular oxygen), GO:0016702 (oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0006629 (lipid metabolic process), GO:0006720 (isoprenoid metabolic process), GO:0006721 (terpenoid metabolic process), GO:0016101 (diterpenoid metabolic process), GO:0001523 (retinoid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0031984 (organelle subcompartment), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0031090 (organelle membrane), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0098827 (endoplasmic reticulum subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0005789 (endoplasmic reticulum membrane)
Protein: Fanconi anemia group G protein (Q7SZH6)
Organism: Gallus gallus (Chicken)
Function: Not known
Sequence: MKRLRCGTAPEPGCLQAWAAECEALAGRWRAARGSAYGGAAAAARQLRGAFGELLLQMRGLPPALPMMPLELTVLYNSLLFVMGTSDCAIKGEAEGIRQGLLRVLEACGTSGQDPSTQKLWQKVLQEVTVEELQAPLHRLGALQAAWWLATSCLQNIIDLFRLLSSAEDPERAPCRAEKNELLTLLKAWRTPAEEASVSLVQSTEDLKETLCTAAAFLQGLQELEAGNLSTTLCLLQEAAGGFCSKRVLAQIYVCLGCCAQRMGKPQTALQHLKQALQVDFQCHPALSHTAAVYHELGETDAELQALYLLYEAVEKNPPSATSSSTYFLIRAELLVNTPILASLLRHHHPSEVKYLLAQRCLRDGRVADAVEHYLDFLSLLQEGLQQQVPLDGGSPLPRIPEVSLEAASALEQDGRHQDSLTVCDEVISRTTNLIPKIIQVEEKLEQPECASLETGLAGGLLSQKRESLCCLTWRAAAYLHQGWVWSKLGKGKEAIMQFSRCLNDLLRFQPRGCGVEPAESLLPEVKVLQKIRLLSLIGRGMQFLEQEKHKEALLDFQHGLQISPDDPAAASYLVQVLWKLNRKEEAADYWQKYLESPAGEDGQQERQGRHFPLYLDSCLKQATFPQNESLARCIQDYLRTTRQDSSR
InterPro domains: - IPR039684: Fanconi anemia group G protein (family) [7-643]
- IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [137-615]
- IPR019734: Tetratricopeptide repeat (repeat) [250-567]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0009410 (response to xenobiotic stimulus), GO:0070887 (cellular response to chemical stimulus), GO:0006805 (xenobiotic metabolic process), GO:0071466 (cellular response to xenobiotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Golgi reassembly stacking protein (GRASP homologue), putative (Q386P4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004394}.
Sequence: MGQGKSDAKRPLKDIEGLQIVRVLPYSPSHSAGLIPFFDIITAVDGKQMEVDGESVEKFKYYVAGRRDETITLTVYNLYIHNYRDVHCVASSTWGGGGLLGCSVEWCQAEKCVERCWHVVDVIPGSPVAKCGEIKEGRDYIIGIQKADELVTALIKDEDDLYTRVELWRTAQSAALRRLQRNSFVPTGASREDRGLQTAGQLLLLVYDSVNIEVKEVLVDFGNDIYAPLGMNLATGLLHLIPSPPKSLADNGRVTGTVGISATSAGDDSSCSVNSSSNLPTVTAFVLATGGVLRIGKTAPTVLAPPKPGATGSPNGPPPPFTSPVVTEMQAPQMLPEFPSRVHVPPQKYHAAANSTAFPKEIEGVHEQPPTPLFPMEGIPNGLHAPLPNPAGLFMNTVSPRKWQEDVAAVATIPAAEGNPSCATTSHDPPVPSYSAQQHTQQQFGLPFSQASYQQQPPPQIIRQSLLPDVTNMVDEQLPVSRVPPPLAFPIIKPATPSR
InterPro domains: - IPR024958: GRASP-type PDZ domain (domain) [16-243]
- IPR036034: PDZ superfamily (homologous_superfamily) [1-249]
- IPR007583: GRASP55/65 (family) [1-451]
Interaction partners: - Vesicle tethering protein Uso1/P115-like head domain-containing protein
- Sec1 family transport protein, putative
- Syntaxin 5
- peptidylprolyl isomerase
- Uncharacterized protein
- Protein transport protein SEC23
- Protein transport protein SEC23
- 26S proteasome regulatory subunit 4 homolog
- Cornichon protein
- Vesicle-associated membrane protein, putative
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051301 (cell division), GO:0022402 (cell cycle process), GO:0007049 (cell cycle), GO:0000278 (mitotic cell cycle), GO:0000910 (cytokinesis), GO:1903047 (mitotic cell cycle process), GO:0061640 (cytoskeleton-dependent cytokinesis), GO:0000281 (mitotic cytokinesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0042995 (cell projection), GO:0020016 (ciliary pocket), GO:0043227 (membrane-bounded organelle), GO:0120025 (plasma membrane bounded cell projection), GO:0005929 (cilium)
Protein: Serine/threonine-protein phosphatase 2A activator (EC 5.2.1.8) (Phosphotyrosyl phosphatase activator) (PTPA) (Q9VQQ0)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000255|RuleBase:RU361210, ECO:0000269|PubMed:26586222}. Nucleus {ECO:0000269|PubMed:26586222}. Note=Enriched in nuclei during interphase and dispersed evenly throughout the cytoplasm after breakdown of the nuclear envelope in mitosis. {ECO:0000269|PubMed:26586222}.
Sequence: MASGINQAAGKLPAIAKKVQNLGDMGVWQKSRAFHDLIGYINGTSSAIQGIKTTDEIFESEMLKKLLRLFDALEKLVEQNPPLEQPQRFGNKAYRDWAQAMRELLPELLEQLLPDDKKRYQVELGQYLTESFGNATRIDYGTGHELSFLFFLCSLFKAEILQERDIVSAALRLFNRYLELARQLQRTYNMEPAGSQGVWSLDDFQFVPFIWGSAQLAVKSPFDPSKFVDEAIITEYKDHFMFISCIDYICKVKTGHFGEHSNQLWSITDVPTWAKINAGLVKMYQKEILSKFPVIQHVYFGELMTFEPVSSGTTLSNARLGHVAPPPSKRICIGTPNLVPPVPVATAPPPPAESLSIEQNVGDSSSESSDNSVVLRPSTSSSSLVAAAEGSGDKPSKE
InterPro domains: - IPR043170: Phosphotyrosyl phosphatase activator, C-terminal lid domain (homologous_superfamily) [201-314]
- IPR004327: Phosphotyrosyl phosphatase activator, PTPA (family) [13-309]
- IPR037218: PTPA superfamily (homologous_superfamily) [17-308]
Interaction partners: - Serine/threonine-protein phosphatase 4 regulatory subunit 2
- Serine/threonine-protein phosphatase PP2A
- Serine/threonine-protein phosphatase 4 catalytic subunit
- Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit
- Serine/threonine-protein phosphatase 4 regulatory subunit 3
- Serine/threonine-protein phosphatase
- Uncharacterized protein, isoform B
- LD07294p
- Serine/threonine-protein phosphatase 2B catalytic subunit 2
- Serine/threonine-protein phosphatase 2B catalytic subunit 3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0019902 (phosphatase binding), GO:0019903 (protein phosphatase binding), GO:0008157 (protein phosphatase 1 binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0009987 (cellular process), GO:0051179 (localization), GO:0050793 (regulation of developmental process), GO:0051641 (cellular localization), GO:0032879 (regulation of localization), GO:0033036 (macromolecule localization), GO:0050794 (regulation of cellular process), GO:0070727 (cellular macromolecule localization), GO:0060341 (regulation of cellular localization), GO:0032880 (regulation of protein localization), GO:0008104 (protein localization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: V(D)J recombination-activating protein 1 (EC 2.3.2.27) (EC 3.1.-.-) (Q68AY0)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|RuleBase:RU366024}.
Sequence: VKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRVTVEHGSQNVKIFEEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELLLEMGGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDATRLEASQNLVFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQLEIGEVYKNPNASKEERKRWQATLDKHLRKRMNLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYR
InterPro domains: - IPR024627: V(D)J recombination-activating protein 1 (family) [1-333]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:1901363 (heterocyclic compound binding), GO:0097159 (organic cyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0019899 (enzyme binding), GO:0003677 (DNA binding), GO:0042826 (histone deacetylase binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048583 (regulation of response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0051239 (regulation of multicellular organismal process), GO:0003008 (system process), GO:0007610 (behavior), GO:0050877 (nervous system process), GO:0050795 (regulation of behavior), GO:0007611 (learning or memory), GO:0009314 (response to radiation), GO:0080134 (regulation of response to stress), GO:0007632 (visual behavior), GO:0008542 (visual learning), GO:0031347 (regulation of defense response), GO:0009416 (response to light stimulus), GO:0050890 (cognition), GO:0007612 (learning), GO:0008306 (associative learning)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: MotC (G3XD73)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane {ECO:0000256|RuleBase:RU004057}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU004057}.
Sequence: MDVLSLVGIILAFVAIVGGNFLEGGHAGALLNGPAALIVIGGTLAAALLQTPVNVLKRGLGMLGWVFFPPREDLSGGIDRIVSWSMTARKEGLLGLESIADAEPDPYARKGLQLLVDGAEPEVIRSILEVDLFTQESRDLQAAKVFESMGGYAPTIGIIGAVMGLIHVMGNLANPAQLGSGIAVAFVATIYGVGFANLLLLPIGNKLKTLVLRQSRYREMLLEGLLSIAEGENPRSIELKLQGFMD
InterPro domains: - IPR047055: Motility protein A-like (family) [1-245]
- IPR046786: Motility protein A, N-terminal (domain) [6-68]
- IPR002898: MotA/TolQ/ExbB proton channel (domain) [102-220]
Interaction partners: - MotD
- Chemotaxis protein MotB
- Flagellar motor switch protein FliG
- Flagellar motor switch protein FliM
- Flagellar motor switch protein FliN
- Flagellar basal-body rod protein FlgC
- Flagellar basal-body rod protein FlgG
- Flagellar biosynthesis protein FlhA
- Flagellar biosynthetic protein FliQ
- Flagellar biosynthetic protein FliP
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0015267 (channel activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0015085 (calcium ion transmembrane transporter activity), GO:0005261 (monoatomic cation channel activity), GO:0005262 (calcium channel activity), GO:0046873 (metal ion transmembrane transporter activity), GO:0046915 (transition metal ion transmembrane transporter activity), GO:0048731 (system development)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0048870 (cell motility), GO:0001539 (cilium or flagellum-dependent cell motility), GO:0097588 (archaeal or bacterial-type flagellum-dependent cell motility), GO:0071973 (bacterial-type flagellum-dependent cell motility), GO:0071978 (bacterial-type flagellum-dependent swarming motility)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0048870 (cell motility), GO:0001539 (cilium or flagellum-dependent cell motility)
Protein: Aldo-keto reductase family 1 member C4 (Q1HE49)
Organism: Sus scrofa (Pig)
Function: Not known
Sequence: MALNRCVKLNDGHLMPVLGLGTLVSEGVPKSKAGEATRVAIEVGYRHIDAAYVYENEEEVGSALREKIADGTVKREELFYTTKLWATFFRPELVRPALERSLKKLRLDYVDLFIIHVPITMKPGEELLPKDASGKVIFDTVDLRDTWAALEKCKDAGLTKSIGVSNFNHKQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRNSKWVEESNPYLLEDPVLNAIAKKHNRSPAQVALRYQLQRGVVVLAKSFNEQRIKENFQVFDFELPSEDMKTIDGLNQNLRYFKLLFAVDHPYYPYSEEY
InterPro domains: - IPR036812: NAD(P)-dependent oxidoreductase domain superfamily (homologous_superfamily) [2-322]
- IPR023210: NADP-dependent oxidoreductase domain (domain) [18-299]
- IPR044482: Aldo-keto reductase family 1 member C (family) [5-307]
- IPR018170: Aldo/keto reductase, conserved site (conserved_site) [44-282]
- IPR020471: Aldo-keto reductase (family) [1-322]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor), GO:0004033 (aldo-keto reductase (NADP) activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0006082 (organic acid metabolic process), GO:0006631 (fatty acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0016053 (organic acid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0006633 (fatty acid biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0033559 (unsaturated fatty acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process), GO:0046456 (icosanoid biosynthetic process), GO:0072330 (monocarboxylic acid biosynthetic process), GO:0006636 (unsaturated fatty acid biosynthetic process), GO:0006692 (prostanoid metabolic process), GO:0032787 (monocarboxylic acid metabolic process), GO:0006690 (icosanoid metabolic process), GO:0006693 (prostaglandin metabolic process), GO:0046457 (prostanoid biosynthetic process), GO:0001516 (prostaglandin biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Growth hormone (H6ULW9)
Organism: Gallus gallus (Chicken)
Function: Not known
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613, ECO:0000256|RuleBase:RU003618}.
Sequence: MAPGSWFSPLLIAVVTLGLPQEAAATFPAMPLSNLFANAVLRAQHLHLLAAETYKEFERTYIPEDQWYTNKNSQAAFCYSETIPAPTGKDDAQQKSDMEVVRFSLVFIQSWLTPVQYLSKVFTNKLVFGTSDRVFEKLKDLEEGIQALMRELEDRSPRGPQLLRPTYDKFDIHLRNEDALLKNYGLLSCFKKDLHKVETYLKVMKCRRFGESNCTI
InterPro domains: - IPR018116: Somatotropin hormone, conserved site (conserved_site) [78-206]
- IPR034975: Somatotropin (family) [35-214]
- IPR001400: Somatotropin/prolactin (family) [4-214]
- IPR009079: Four-helical cytokine-like, core (homologous_superfamily) [20-214]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008234 (cysteine-type peptidase activity), GO:0004175 (endopeptidase activity), GO:0004197 (cysteine-type endopeptidase activity), GO:0097153 (cysteine-type endopeptidase activity involved in apoptotic process)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0048519 (negative regulation of biological process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0003006 (developmental process involved in reproduction), GO:0048523 (negative regulation of cellular process), GO:0009892 (negative regulation of metabolic process), GO:0035295 (tube development), GO:0060548 (negative regulation of cell death), GO:0010941 (regulation of cell death), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0009888 (tissue development), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0048731 (system development), GO:0060255 (regulation of macromolecule metabolic process), GO:0048608 (reproductive structure development), GO:0061458 (reproductive system development), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:0010628 (positive regulation of gene expression), GO:0060066 (oviduct development), GO:0060429 (epithelium development), GO:0010629 (negative regulation of gene expression), GO:0010468 (regulation of gene expression), GO:0042981 (regulation of apoptotic process), GO:0043066 (negative regulation of apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Succinate-CoA ligase ADP-forming subunit beta (Q5T9Q5)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: SGRGHPSEPPASDGPAGCCSGSKDVVIKAQVLAGGRGKGTFESGLKGGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQGPVLIGSSHGGVNIEDVAAESPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESAAENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEAFKLITSDK
InterPro domains: - IPR017866: Succinyl-CoA synthetase, beta subunit, conserved site (conserved_site) [246-270]
- IPR005811: ATP-citrate synthase/succinyl-CoA ligase, C-terminal domain (domain) [251-298]
- IPR016102: Succinyl-CoA synthetase-like (homologous_superfamily) [229-298]
- IPR013815: ATP-grasp fold, subdomain 1 (homologous_superfamily) [21-93]
- IPR013650: ATP-grasp fold, succinyl-CoA synthetase-type (domain) [21-192]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0019637 (organophosphate metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:0006790 (sulfur compound metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0035383 (thioester metabolic process), GO:0006793 (phosphorus metabolic process), GO:0006753 (nucleoside phosphate metabolic process), GO:0006637 (acyl-CoA metabolic process), GO:0019693 (ribose phosphate metabolic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0072521 (purine-containing compound metabolic process), GO:0009259 (ribonucleotide metabolic process), GO:0009117 (nucleotide metabolic process), GO:0006163 (purine nucleotide metabolic process), GO:0034032 (purine nucleoside bisphosphate metabolic process), GO:0006104 (succinyl-CoA metabolic process), GO:0033865 (nucleoside bisphosphate metabolic process), GO:0009150 (purine ribonucleotide metabolic process), GO:0033875 (ribonucleoside bisphosphate metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)