Protein: Dystroglycan 1 (Dystroglycan) (Dystrophin-associated glycoprotein 1) (Q9GT67)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Cell membrane, sarcolemma {ECO:0000256|ARBA:ARBA00004135}. Nucleus, nucleoplasm {ECO:0000256|ARBA:ARBA00004642}. Postsynaptic cell membrane {ECO:0000256|ARBA:ARBA00034100}. Secreted, extracellular space {ECO:0000256|ARBA:ARBA00004239}.
Sequence: ATPTSSVATTTASTPESSSISSNFVSTDYMEPQPEENSPPIIKTRLQKLAVTSGKAFTFHVLPETFYDAEDQGNLRLALTDKDGHELKANSWLQFNADKRELYGLPLDDTVSRWQYRLSATDSGNASVTETVEISVQQHRAVRTINHEISVFVRINEKPGHNIDWQLKLINAVARTLDDSTNSAVVVREIRQTPHDPHSATFVYFNETLPTSECPEKELKDIIARLDANRLSDLVQPQLGIKSITGQLIGSCQKDLTQVKPTQHMTKNVPPMPRNQVDRVNASLGQLLVYKVPADTFYDANDNQLTLTLKTRDHLELSPRHWLQFDSKNEEFYGIPKSGDIGSEEYLLVAEDSGGLSAHDALVVVVSPAPKRDFGFFFKAYLSIKHERFNADLQRKFVERVAKLNGDPTTGQIQIRSITTHHDSDGTIVNFYNTTLYRKHNSCREKEVAMTRSVYLNSDLSLREAAKRALGPELNLTNFSVVPFSICHHTENIDTNQLDYIPSRPEEPTHKSSFGEDYMITFVWPIVIIVAMLVAASIIACCLHWCRQRSGKMELGDEEERKSFRAKGIPVIFQDEYEEKPEIGNKSPVILKDEKPPLLPPSYNTSNMNGDNDVDDYVPPPSVVVGGREVRGKSPATPSYRKPPPYVSP
InterPro domains: - IPR030398: DG-type SEA domain (domain) [144-486]
- IPR008465: Dystroglycan, C-terminal (domain) [376-649]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [33-372]
- IPR006644: Dystroglycan-type cadherin-like (domain) [41-373]
- IPR015919: Cadherin-like superfamily (homologous_superfamily) [40-370]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0040011 (locomotion), GO:0022414 (reproductive process), GO:0042592 (homeostatic process), GO:0040007 (growth), GO:0009605 (response to external stimulus), GO:0019953 (sexual reproduction), GO:0048589 (developmental growth), GO:0048856 (anatomical structure development), GO:0009653 (anatomical structure morphogenesis), GO:0042221 (response to chemical), GO:0007163 (establishment or maintenance of cell polarity), GO:0042330 (taxis), GO:0007389 (pattern specification process), GO:0071840 (cellular component organization or biogenesis), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0009791 (post-embryonic development), GO:0065008 (regulation of biological quality), GO:0019725 (cellular homeostasis), GO:0016203 (muscle attachment), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0050794 (regulation of cellular process), GO:0023051 (regulation of signaling), GO:0021700 (developmental maturation), GO:0048869 (cellular developmental process), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0030029 (actin filament-based process), GO:0048609 (multicellular organismal reproductive process), GO:0032989 (cellular component morphogenesis), GO:0002165 (instar larval or pupal development), GO:0007552 (metamorphosis), GO:0048729 (tissue morphogenesis), GO:0044085 (cellular component biogenesis), GO:0030010 (establishment of cell polarity), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007308 (oocyte construction), GO:0050803 (regulation of synapse structure or activity), GO:0016334 (establishment or maintenance of polarity of follicular epithelium), GO:0071695 (anatomical structure maturation), GO:0009894 (regulation of catabolic process), GO:0000902 (cell morphogenesis), GO:0009887 (animal organ morphogenesis), GO:0048469 (cell maturation), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0061245 (establishment or maintenance of bipolar cell polarity), GO:0016043 (cellular component organization), GO:0009790 (embryo development), GO:0009994 (oocyte differentiation), GO:0009886 (post-embryonic animal morphogenesis), GO:0006935 (chemotaxis), GO:0010927 (cellular component assembly involved in morphogenesis), GO:0007276 (gamete generation), GO:0048736 (appendage development), GO:0007281 (germ cell development), GO:0007309 (oocyte axis specification), GO:0009798 (axis specification), GO:0007293 (germarium-derived egg chamber formation), GO:0046716 (muscle cell cellular homeostasis), GO:0035107 (appendage morphogenesis), GO:0030036 (actin cytoskeleton organization), GO:0009880 (embryonic pattern specification), GO:0061061 (muscle structure development), GO:0009888 (tissue development), GO:0003002 (regionalization), GO:0010646 (regulation of cell communication), GO:0062012 (regulation of small molecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0099177 (regulation of trans-synaptic signaling), GO:0080090 (regulation of primary metabolic process), GO:0030030 (cell projection organization), GO:0097485 (neuron projection guidance), GO:0032990 (cell part morphogenesis), GO:0048707 (instar larval or pupal morphogenesis), GO:0002009 (morphogenesis of an epithelium), GO:0007350 (blastoderm segmentation), GO:0048666 (neuron development), GO:0009948 (anterior/posterior axis specification), GO:0022607 (cellular component assembly), GO:0006140 (regulation of nucleotide metabolic process), GO:0060025 (regulation of synaptic activity), GO:0000904 (cell morphogenesis involved in differentiation), GO:0007399 (nervous system development), GO:0042692 (muscle cell differentiation), GO:0048737 (imaginal disc-derived appendage development), GO:0007292 (female gamete generation), GO:0048599 (oocyte development), GO:0048563 (post-embryonic animal organ morphogenesis), GO:0007560 (imaginal disc morphogenesis), GO:0007444 (imaginal disc development), GO:0048858 (cell projection morphogenesis), GO:0035282 (segmentation), GO:0007314 (oocyte anterior/posterior axis specification), GO:0043470 (regulation of carbohydrate catabolic process), GO:0055001 (muscle cell development), GO:0035088 (establishment or maintenance of apical/basal cell polarity), GO:0035120 (post-embryonic appendage morphogenesis), GO:0048477 (oogenesis), GO:0050804 (modulation of chemical synaptic transmission), GO:0035114 (imaginal disc-derived appendage morphogenesis), GO:0031532 (actin cytoskeleton reorganization), GO:0006109 (regulation of carbohydrate metabolic process), GO:0030239 (myofibril assembly), GO:0022008 (neurogenesis), GO:0043467 (regulation of generation of precursor metabolites and energy), GO:0048569 (post-embryonic animal organ development), GO:0007474 (imaginal disc-derived wing vein specification), GO:0000578 (embryonic axis specification), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0007517 (muscle organ development), GO:0060429 (epithelium development), GO:0006996 (organelle organization), GO:0031032 (actomyosin structure organization), GO:0007351 (tripartite regional subdivision), GO:0030182 (neuron differentiation), GO:0097435 (supramolecular fiber organization), GO:0051174 (regulation of phosphorus metabolic process), GO:0009952 (anterior/posterior pattern specification), GO:1900542 (regulation of purine nucleotide metabolic process), GO:0007472 (wing disc morphogenesis), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0045214 (sarcomere organization), GO:0007010 (cytoskeleton organization), GO:0008595 (anterior/posterior axis specification, embryo), GO:0007411 (axon guidance), GO:0048699 (generation of neurons), GO:0007476 (imaginal disc-derived wing morphogenesis), GO:0016333 (morphogenesis of follicular epithelium), GO:0070925 (organelle assembly), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0006110 (regulation of glycolytic process), GO:0060538 (skeletal muscle organ development), GO:0120036 (plasma membrane bounded cell projection organization), GO:0019220 (regulation of phosphate metabolic process), GO:0035220 (wing disc development), GO:0051146 (striated muscle cell differentiation), GO:0031175 (neuron projection development), GO:0045197 (establishment or maintenance of epithelial cell apical/basal polarity), GO:0055002 (striated muscle cell development), GO:0048812 (neuron projection morphogenesis), GO:0061564 (axon development), GO:0007409 (axonogenesis), GO:0042325 (regulation of phosphorylation), GO:1903578 (regulation of ATP metabolic process), GO:0008358 (maternal determination of anterior/posterior axis, embryo), GO:0140694 (non-membrane-bounded organelle assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0045178 (basal part of cell), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030315 (T-tubule), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0090665 (glycoprotein complex), GO:0030017 (sarcomere), GO:0031674 (I band), GO:0030018 (Z disc), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0098796 (membrane protein complex), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0098797 (plasma membrane protein complex), GO:0016010 (dystrophin-associated glycoprotein complex), GO:0009925 (basal plasma membrane), GO:0043292 (contractile fiber), GO:0098590 (plasma membrane region), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0005886 (plasma membrane), GO:0043228 (non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0042383 (sarcolemma), GO:0030016 (myofibril), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031594 (neuromuscular junction)