Protein: 40S ribosomal protein S15a (H3BN98)
Organism: Homo sapiens (Human)
Subcellular location: Membrane; Multi- pass membrane protein
Sequence: MAEGDNRSTNLLAAETASLEEQLQGWGEVMLMADKVLRWERAWFPPAIMGVVSLVFLIIYYLDPSVLSGVSCFVMFLCLADYLVPILAPRIFGSNKWTTEQQQRFHEICSNLVKTRRRAVGWWKRLFTLKEEKPKMYFMTMIVSLAAVAWVGQQVHNLLLTYLIATMVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNK
InterPro domains: - IPR035987: Small ribosomal subunit protein uS8 superfamily (homologous_superfamily) [169-237]
- IPR052114: ER-associated autophagy and membrane dynamics regulator (family) [1-169]
- IPR000630: Small ribosomal subunit protein uS8 (family) [172-232]
- IPR057282: RETREG1-3/ARL6IP-like, N-terminal reticulon-homology domain (domain) [26-168]
Interaction partners: - Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein
- Small ribosomal subunit protein uS13
- Small ribosomal subunit protein uS19
- Small ribosomal subunit protein eS1
- Large ribosomal subunit protein eL31
- Small ribosomal subunit protein eS28
- Large ribosomal subunit protein uL15
- Small ribosomal subunit protein eS8
- Large ribosomal subunit protein uL14
- Small ribosomal subunit protein eS21
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0046983 (protein dimerization activity), GO:0042803 (protein homodimerization activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0065009 (regulation of molecular function), GO:0048523 (negative regulation of cellular process), GO:0009892 (negative regulation of metabolic process), GO:0050790 (regulation of catalytic activity), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0060548 (negative regulation of cell death), GO:0010941 (regulation of cell death), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0044092 (negative regulation of molecular function), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0016043 (cellular component organization), GO:0080090 (regulation of primary metabolic process), GO:0051128 (regulation of cellular component organization), GO:0043086 (negative regulation of catalytic activity), GO:0043069 (negative regulation of programmed cell death), GO:0010256 (endomembrane system organization), GO:0051246 (regulation of protein metabolic process), GO:0043067 (regulation of programmed cell death), GO:0051336 (regulation of hydrolase activity), GO:0051248 (negative regulation of protein metabolic process), GO:0061024 (membrane organization), GO:0033043 (regulation of organelle organization), GO:0006996 (organelle organization), GO:0022607 (cellular component assembly), GO:0042981 (regulation of apoptotic process), GO:0007029 (endoplasmic reticulum organization), GO:0051346 (negative regulation of hydrolase activity), GO:0030162 (regulation of proteolysis), GO:0090158 (endoplasmic reticulum membrane organization), GO:0052547 (regulation of peptidase activity), GO:0043066 (negative regulation of apoptotic process), GO:0045861 (negative regulation of proteolysis), GO:0043154 (negative regulation of cysteine-type endopeptidase activity involved in apoptotic process), GO:0052548 (regulation of endopeptidase activity), GO:0010466 (negative regulation of peptidase activity), GO:0071786 (endoplasmic reticulum tubular network organization), GO:0010951 (negative regulation of endopeptidase activity), GO:2000116 (regulation of cysteine-type endopeptidase activity), GO:2000117 (negative regulation of cysteine-type endopeptidase activity), GO:0043281 (regulation of cysteine-type endopeptidase activity involved in apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)