Protein: Transcription factor WRKY45-1 (OsWRKY45-1) (OsWRKY45) (WRKY transcription factor 45-2) (Q5W6D6)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcriptional activator involved in defense responses against pathogens. Acts as positive regulator of defense responses against the rice blast fungus Magnaporthe oryzae. Acts through W-boxes, which are cis-elements that are enriched in the promoters of several defense-related genes. Plays an important role in the benzothiadiazole-induced disease resistance by mediating salicylic acid (SA) defense signaling pathway, independently of the disease resistance gene NPR1/NH1. Acts as negative regulator of defense responses against the bacterial blight Xanthomonas oryzae pv oryzae (Xoo) and the bacterial streak Xanthomonas oryzae pv oryzicola (Xoc). Acts downstream of abscisic acid (ABA) signaling in response to the rice blast fungus. ABA is a negative regulator of defense responses that interacts antagonistically with salicylic acid (SA) signaling pathway. Acts as negative regulator of ABA signaling that suppresses growth of seedlings. Does not seem to be involved in the regulation of salt stress response. Acts as negative regulator of cold stress response. Acts as negative regulator of drought stress response.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00223}.
Sequence: MTSSMSPAPAPAYAQVMEDMEKGKELAAQLQGLLRDSPEAGRFVDQILHTFSRAMRALDKAAVSAAGGEGSEVQSEVTCGGGASAGGKRKAPAADRKANCRRRTQQSSGNSVVVKNLDDGQAWRKYGQKEIQNSKHPKAYFRCTHKYDQLCTAQRQVQRCDDDPASYRVTYIGEHTCRDPATAPIIAAHVIHQVAAGDNDDGCGGLQAGSRLISFVAAPAAPVDAAAAPTTSTITTVTAPGPLLQPLKVEGGVGSSDQEEVLSSLTPGSSAARGGGGGGGVAGPFGPDQGDVTSSLHWSYDAVAGMEFFKNDEVVFDLDDIMGLSF
InterPro domains: - IPR044810: WRKY transcription factor, plant (family) [17-188]
- IPR003657: WRKY domain (domain) [112-180]
- IPR036576: WRKY domain superfamily (homologous_superfamily) [101-181]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0048583 (regulation of response to stimulus), GO:0009605 (response to external stimulus), GO:0023051 (regulation of signaling), GO:0006950 (response to stress), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0050794 (regulation of cellular process), GO:0006952 (defense response), GO:0043207 (response to external biotic stimulus), GO:0010646 (regulation of cell communication), GO:0009620 (response to fungus), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0009966 (regulation of signal transduction), GO:0050832 (defense response to fungus), GO:0042742 (defense response to bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)