wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Bowman-Birk type proteinase inhibitor 2a (LSI-2a) (P86932)
Organism: Lathyrus sativus (White vetchling)
Function: Inhibits trypsin (IC(50)=0.9 nM) and alpha-chymotrypsin (IC(50)=1.1 nM).
Sequence: GDDVKSACCDTCLCTKSNPPTCRCVDVGETCHSACLSCICAYSYPPKCQCFDTQKFCYRACHNSEKEEVIKG
InterPro domains: - IPR035995: Bowman-Birk type proteinase inhibitor (homologous_superfamily) [1-72]
- IPR000877: Proteinase inhibitor I12, Bowman-Birk (domain) [8-61]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140678 (molecular function inhibitor activity), GO:0061134 (peptidase regulator activity), GO:0004857 (enzyme inhibitor activity), GO:0061135 (endopeptidase regulator activity), GO:0030414 (peptidase inhibitor activity), GO:0004866 (endopeptidase inhibitor activity), GO:0004867 (serine-type endopeptidase inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0065009 (regulation of molecular function), GO:0019222 (regulation of metabolic process), GO:0009892 (negative regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0050790 (regulation of catalytic activity), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0044092 (negative regulation of molecular function), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0043086 (negative regulation of catalytic activity), GO:0051246 (regulation of protein metabolic process), GO:0051336 (regulation of hydrolase activity), GO:0051248 (negative regulation of protein metabolic process), GO:0052547 (regulation of peptidase activity), GO:0045861 (negative regulation of proteolysis), GO:0051346 (negative regulation of hydrolase activity), GO:0030162 (regulation of proteolysis), GO:0052548 (regulation of endopeptidase activity), GO:0010466 (negative regulation of peptidase activity), GO:0010951 (negative regulation of endopeptidase activity)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Protein ECM23 (Extracellular mutant protein 23) (SRD1 homolog 2) (Q02710)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Involved in morphogenesis. May be involved in cell wall organization and biogenesis.
Sequence: MLYNKEQGTSGASSSGRRTKFHFDRFVQMVLFIAANPNYCCSVASIPKSGVTPDLKRADILEQKIKSLNSALSPKLKEESRLGGPLHNPSILPAPSFSSLPISSNGKKSLAGYRPKSRKKQTILPNGQPKECATCGDTWTSQWRSGPNGNVELCSRCGIAYRKKMEKKIRSQQSSDDGTKNFIFKNK
InterPro domains: - IPR000679: Zinc finger, GATA-type (domain) [126-178]
- IPR013088: Zinc finger, NHR/GATA-type (homologous_superfamily) [127-183]
Interaction partners: - Protein GAT3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0042254 (ribosome biogenesis), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0034470 (ncRNA processing), GO:0006364 (rRNA processing), GO:0034660 (ncRNA metabolic process), GO:0016072 (rRNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Ribosomal protein S4 (Q2F8W8)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Not known
Sequence: MPALRFKTCRLLPGNVRNRELSLIQRRILRRLRNKRRSIKRNLSQRENLNSNIKSQTTRKLSLYYGDLPIREMHRGRERTSYIPFLLNQETRSDVIPVRLHFCDTLPQARQPISHRRVCLNNGLVTITHLKVSHGDLISFQENDARTRGEEIRRSFYIDISVGKIIGKLLPVRIWRKTKTEWFRLLTTQRVCRLLLKSWFLQELRSYMQEEDLERTKKFGSAKVCLGSSFAEHNRMKRNLFHFKYFFLLKRRKEEEELIRTIGEAENRKRAISPFVYKSSLYRNSTYCSGSPFTRKIRIKRIELPTHYSEVNHRTLKAVVSYGPNIGHIPHDIRLKDPNLPLRSGNGRGQNI
InterPro domains: - IPR002942: RNA-binding S4 domain (domain) [91-152]
- IPR036986: RNA-binding S4 domain superfamily (homologous_superfamily) [90-173]
- IPR022801: Small ribosomal subunit protein uS4 (family) [5-264]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0019538 (protein metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006412 (translation), GO:0009059 (macromolecule biosynthetic process), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:0006518 (peptide metabolic process), GO:0010467 (gene expression), GO:0043043 (peptide biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Transcription factor IIIA (TFIIIA) (P79797)
Organism: Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Function: Involved in ribosomal large subunit biogenesis. Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's (By similarity).
Subcellular location: Nucleus.
Sequence: MGERFKDPAKNFVCSFLNCKASFSKAWKLEAHYCKHTGLRPFACDRCDKTFCTRCQLTRHNLSHSGKKPYQCLEDGCSESFISTAGLKNHVERVHQHKEKHYVCDYEGCAKEFRKKKQLRSHKCEHMNQLPFECQYEGCGKKYTTSKKLQKHEKVHDVYPCAEEGCDFQGRMWTEYQAHRKAAHREALQCDSCAKVFHKAWFLKKHKLFVHLGVRRVFKCTKEGCQKTYTTHFNLQNHILSFHEGIRSFICPHDGCGKAFAMEGSLKRHAVVHDPQKKKLQKKTKRGRKKKLEPKTNVSDDSELPAQLHGLSLNTSTSQNNP
InterPro domains: - IPR051061: Zinc finger transcriptional regulators (family) [12-312]
- IPR013087: Zinc finger C2H2-type (domain) [12-278]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [12-276]
- IPR054599: Transcription factor IIIA, beta-beta-alpha zinc finger (domain) [148-179]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding), GO:0000987 (cis-regulatory region sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0045927 (positive regulation of growth), GO:0048522 (positive regulation of cellular process), GO:0040008 (regulation of growth), GO:0050794 (regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0001558 (regulation of cell growth), GO:0030307 (positive regulation of cell growth)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: NAD(P)-linked oxidoreductase superfamily protein (Q949S6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MAASSSIPPSTAVTSVVRKSLLLSTTFSFPASSLSPSTKLPQRHIQRLLLASSSASASTVPSDSKPAKKETVYFDGGAHYGDLLANLILGLTILWLPLTLAAVSRAFNLRYRFTNLRVTVISGLTGDDRSDFSYKVIKDVQVVPRFIGEWGDIIITLKDGTKVDLRSVPKFREIAKYCLSMADQPAVLKESGAKGF
InterPro domains: - IPR005182: YdbS-like, PH domain (domain) [107-178]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0009657 (plastid organization), GO:0009658 (chloroplast organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Two-component response regulator (Q9I529)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Sequence: MFPSLTPDPRLLAIEDDPTLGAHLFQHLNGSGFEVTWCRDGEEGLAAARSGGYDLILMDIMLPGRDGLEILRQLRQEQALPVILMSALGAEQDRIAGFSQGADDYLPKPFSLAELRVRIDAILRRIALERGGAPGRCAEPLARPSLQFSADVCDVSLGERFAGLTPTEYRLLETFLAAEGETLTKAFLYQHVLHRGHTQHDRSLDMHVSHLRRKLQRLGYAGHQLHTVWGKGYVLTPAP
InterPro domains: - IPR001789: Signal transduction response regulator, receiver domain (domain) [9-123]
- IPR039420: Transcriptional regulatory protein WalR-like (family) [10-236]
- IPR011006: CheY-like superfamily (homologous_superfamily) [7-178]
- IPR001867: OmpR/PhoB-type DNA-binding domain (domain) [138-237]
- IPR016032: Signal transduction response regulator, C-terminal effector (homologous_superfamily) [154-235]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [140-238]
Interaction partners: - histidine kinase
- Sensor protein PfeS
- Transcriptional activator protein PfeR
- histidine kinase
- histidine kinase
- HTH gntR-type domain-containing protein
- Probable transcriptional regulator
- Probable transcriptional regulator
- histidine kinase
- Sensor protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0000156 (phosphorelay response regulator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009893 (positive regulation of metabolic process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0045834 (positive regulation of lipid metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0009891 (positive regulation of biosynthetic process), GO:0009889 (regulation of biosynthetic process), GO:0046889 (positive regulation of lipid biosynthetic process), GO:0046890 (regulation of lipid biosynthetic process), GO:0010562 (positive regulation of phosphorus metabolic process), GO:0019216 (regulation of lipid metabolic process), GO:1903727 (positive regulation of phospholipid metabolic process), GO:0051174 (regulation of phosphorus metabolic process), GO:1903725 (regulation of phospholipid metabolic process), GO:0045937 (positive regulation of phosphate metabolic process), GO:0071073 (positive regulation of phospholipid biosynthetic process), GO:0071071 (regulation of phospholipid biosynthetic process), GO:0019220 (regulation of phosphate metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0032993 (protein-DNA complex)
Protein: Protein kreg-1 (Q20689)
Organism: Caenorhabditis elegans
Function: Plays a role in the stress response to heavy metals such as copper, probably in a fos-1/kgb-1-dependent manner.
Sequence: MSYYGNGGYNPYGAYGNVPPPVYGTPGLAPPTVHVHTDGGHHHGHHHHHHSFLHELGHALTGHHHHHHGHHFGHHHHHHHGHH
InterPro domains: - IPR040232: Protein Kreg-1 (family) [1-83]
Interaction partners: - Lysozyme-like protein 3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0002376 (immune system process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0006955 (immune response), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0045087 (innate immune response), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Type 3 secretion system secretin (T3SS secretin) (B7UMB3)
Organism: Escherichia coli O127:H6 (strain E2348/69 / EPEC)
Function: Not known
Subcellular location: Cell outer membrane {ECO:0000256|ARBA:ARBA00004442, ECO:0000256|HAMAP-Rule:MF_02219, ECO:0000256|RuleBase:RU004004}.
Sequence: MKKISFFIFTALFCCSAQAAPSSLEKRLGKNEYFIITKSSPVRAILNDFAANYSIPVFISSSVNDDFSGEIKNEKPVKVLEKLSKLYHLTWYYDENILYIYKTNEISRSIITPTYLDIDSLLKYLSDTISVNKNSCNVRKITTFNSIEVRGVPECIKYITSLSESLDKEAQSKAKNKDVVKVFKLNYASATDITYKYRDQNVVVPGVVSILKTMASNGSLPSTGKGAVERSGNLFDNSVTISADPRLNAVVVKDREITMDIYQQLISELDIEQRQIEISVSIIDVDANDLQQLGVNWSGTLNAGQGTIAFNSSTAQANISSSVISNASNFMIRVNALQQNSKAKILSQPSIITLNNMQAILDKNVTFYTKVSGEKVASLESITSGTLLRVTPRILDDSSNSLTGKRRERVRLLLDIQDGNQSTNQSNAQDASSTLPEVQNSEMTTEATLSAGESLLLGGFIQDKESSSKDGIPLLSDIPVIGSLFSSTVKQKHSVVRLFLIKATPIKSASSE
InterPro domains: - IPR004845: Type II secretion system protein GspD, conserved site (conserved_site) [452-485]
- IPR038591: NolW-like superfamily (homologous_superfamily) [106-273]
- IPR050810: Bacterial Secretion System Channel Protein (family) [25-509]
- IPR049034: SPI-1 type 3 secretion system secretin, N0 domain (domain) [36-101]
- IPR004846: Type II/III secretion system, secretin-like domain (domain) [336-504]
- IPR003522: Type III secretion system outer membrane pore YscC/HrcC (family) [4-507]
- IPR005644: NolW-like (domain) [180-275]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex)
Protein: Spermatogenesis associated 22 (A0A0G2K3H6)
Organism: Rattus norvegicus (Rat)
Function: Not known
Sequence: LLWLLTDGFTGCLPVPLFNQKKRNRQPLTSNPLQSDPGIGTVSDTYGFPSLPTDWAWEAVNPVVAPLKKTVNTGQIPASASYPLRIEDPVCKSIESNAKRSQGGGGYRGNNRNTSSRTWDRNDFRPQHKTVSPAANSEFSSGPVNLGAQRQKQFQTPEFPNLPGHKEAEVPRQTYLSKLPGSTMKGPDRASALQAFKPSFQQNPFNKTVLGDVPRENSLKETTLYQLKEKDNSLRIISAVIESMKYWQAQVKKTVLLFEVLAVLDSAVTPGPHYSKTFLMRDGKNILPCVFYEIDRELPRLIRGRVHRCVGHYDPHKNIFKCVSVRPASASEQKTFQAFVTIVDAEMKYHTKVMNEM
InterPro domains: - IPR033536: Spermatogenesis-associated protein 22 (family) [10-357]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003697 (single-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0019953 (sexual reproduction), GO:0051301 (cell division), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0007276 (gamete generation), GO:0007283 (spermatogenesis), GO:0048137 (spermatocyte division), GO:0048232 (male gamete generation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome)
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (A4GW50)
Organism: Rattus norvegicus (Rat)
Function: Not known
Sequence: MAMTAGATTTFPMSSHTRERVTVAKLTLENFYSNLILQHEERETRQKKLEVAMEEEGLADEEKKLRRSQHARKETEFLRLKRTRLGLDDFESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVAHIRAERDILVEADGAWVVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETVLAIDAIHQLGFIHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSKRKAETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGFPPFCSETPQETYRKVMSWKETLAFPPEVPVSEKAKDLILRFCTDSENRIGNGGVEEIKGHPFFEGVDWGHIRERPAAIPIEIRSIDDTSNFDDFPESDILQPVPNTTEPDYKSKDWVFLNYTYKRFEGLTQRGSIPTYMKAGKL
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [73-429]
- IPR050839: Rho-associated Serine/Threonine Kinase (family) [58-443]
- IPR000719: Protein kinase domain (domain) [90-383]
- IPR000961: AGC-kinase, C-terminal (domain) [384-453]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [209-221]
- IPR017441: Protein kinase, ATP binding site (binding_site) [96-119]
- IPR017892: Protein kinase, C-terminal (domain) [402-443]
Interaction partners: - MOB kinase activator 1A
- MOB kinase activator 2
- Dual specificity protein phosphatase CDC14A
- Cell division cycle 14B
- MOB kinase activator 1B
- Protein S100-B
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0034330 (cell junction organization), GO:0099173 (postsynapse organization), GO:0050808 (synapse organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction), GO:0045202 (synapse), GO:0098978 (glutamatergic synapse)
Protein: POTRA domain-containing protein (Q9HVG7)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Not known
Subcellular location: Cell outer membrane {ECO:0000256|ARBA:ARBA00004442}.
Sequence: MKPSQWTLRWVTLCGCGMLAASAAAVELPGTVQPSQLDERFKPRSEPQAKPEAPLVVPKQVAPQGSEQIRFKLREIRIEGNTRYDKAVLESYYQHMLGEQVSLAELVDLANRLTAKYRQDGFLLTQVVVPEQSIEGGKVRLQVIEGYLEHVQIKGTVDGPRVRVEELLAPLTEKRPLDADTLERGLLLVGDLPGVNVQSVLSPGQALGSSNLDVALQQQRYEGFVSLDNRGSHYTDPTTLAFGATEFSRLGFYEQIDVLGAISPFSDATRYIQLRGTLPLGGMFAGDTLQIMGSYSKVNPDIPDSVFPFDSVSKSTEGSISYNHPFIRSRSQNLSGGLALQWKDTETRLRDFASDASNPGRDHVRVFQQRLTYDWVDRWMGINLAEVRNNIGLDMWGATKKDDERRSREVADGRFVYLNGNIGRLQGLGGPWSVYGELQWQYSFDPLLPSERFGVGGSGIGRGFAPGNITGDRGFALKLEPRYGQAVGYSWLRSYQAYAFYDWGKTYNLDVDDDEQQKLGSIGAGVRFNLTDQLSFNPEIARQVIGEPADQRDGKRETRVLFNVVARF
InterPro domains: - IPR051544: Two-partner secretion system outer membrane transporter (family) [1-568]
- IPR034746: POTRA domain (domain) [71-146]
- IPR013686: Polypeptide-transport-associated, ShlB-type (domain) [71-146]
- IPR005565: Haemolysin activator HlyB, C-terminal (domain) [208-528]
Interaction partners: - Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS domain-containing protein
- Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS domain-containing protein
- ShlB/FhaC/HecB family hemolysin secretion/activation protein
- Adhesive protein CupB5
- Filamentous haemagglutinin FhaB/tRNA nuclease CdiA-like TPS domain-containing protein
- ShlB/FhaC/HecB family hemolysin secretion/activation protein
- TIGR01459 family HAD-type hydrolase
- POTRA domain-containing protein
- Uncharacterized protein
- POTRA domain-containing protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0140318 (protein transporter activity), GO:0008320 (protein transmembrane transporter activity), GO:0022884 (macromolecule transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0055085 (transmembrane transport), GO:0140352 (export from cell), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0032940 (secretion by cell), GO:0045184 (establishment of protein localization), GO:0071806 (protein transmembrane transport), GO:0006810 (transport), GO:0035592 (establishment of protein localization to extracellular region), GO:0098776 (protein transport across the cell outer membrane), GO:0071702 (organic substance transport), GO:0046903 (secretion), GO:0071705 (nitrogen compound transport), GO:0008104 (protein localization), GO:0009306 (protein secretion), GO:0015031 (protein transport), GO:0071692 (protein localization to extracellular region)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex)