Protein: Glutathione S-transferase Z2 (AtGSTZ2) (EC 2.5.1.18) (GST class-zeta member 2) (Q9ZVQ4)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
Subcellular location: Cytoplasm, cytosol {ECO:0000250}.
Sequence: MSYVTDFYQAKLKLYSYWRSSCAHRVRIALTLKGLDYEYIPVNLLKGDQSDSDFKKINPMGTVPALVDGDVVINDSFAIIMYLDDKYPEPPLLPSDYHKRAVNYQATSIVMSGIQPHQNMALFRYLEDKINAEEKTAWITNAITKGFTALEKLLVSCAGKYATGDEVYLADLFLAPQIHAAFNRFHINMEPFPTLARFYESYNELPAFQNAVPEKQPDTPSTI
InterPro domains: - IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [5-94]
- IPR034330: Glutathione S-transferases, class Zeta , C-terminal (domain) [98-216]
- IPR036282: Glutathione S-transferase, C-terminal domain superfamily (homologous_superfamily) [91-220]
- IPR034333: Glutathione S-transferases, class Zeta , N-terminal (domain) [12-84]
- IPR004046: Glutathione S-transferase, C-terminal (domain) [121-207]
- IPR010987: Glutathione S-transferase, C-terminal-like (domain) [96-221]
- IPR040079: Glutathione transferase family (family) [12-202]
- IPR004045: Glutathione S-transferase, N-terminal (domain) [10-91]
- IPR005955: Glutathione S-transferases, class Zeta (family) [13-219]
Interaction partners: - Fumarylacetoacetase
- Homogentisate 1,2-dioxygenase
- Glutathione S-transferase Z1
- Glutathione S-transferase L3
- Elongation factor 1-beta 1
- Elongation factor 1-delta 2
- Elongation factor 1-beta 2
- Glutathione S-transferase U25
- Glutathione S-transferase L2, chloroplastic
- Probable elongation factor 1-gamma 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016853 (isomerase activity), GO:0016859 (cis-trans isomerase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0098754 (detoxification), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0044281 (small molecule metabolic process), GO:0009407 (toxin catabolic process), GO:0019748 (secondary metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044282 (small molecule catabolic process), GO:0044248 (cellular catabolic process), GO:0006082 (organic acid metabolic process), GO:0009636 (response to toxic substance), GO:0009404 (toxin metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901575 (organic substance catabolic process), GO:0016054 (organic acid catabolic process), GO:1901616 (organic hydroxy compound catabolic process), GO:0043436 (oxoacid metabolic process), GO:0019439 (aromatic compound catabolic process), GO:1901361 (organic cyclic compound catabolic process), GO:0042537 (benzene-containing compound metabolic process), GO:0018958 (phenol-containing compound metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0019336 (phenol-containing compound catabolic process), GO:0046395 (carboxylic acid catabolic process), GO:0032787 (monocarboxylic acid metabolic process), GO:0072329 (monocarboxylic acid catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0005576 (extracellular region), GO:0005773 (vacuole), GO:0042579 (microbody), GO:0048046 (apoplast), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000325 (plant-type vacuole), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle), GO:0005777 (peroxisome), GO:0005634 (nucleus)