Protein: Protein inhibitor of activated STAT, 1 (G3V9T0)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Nucleus, nuclear body {ECO:0000256|ARBA:ARBA00034306}.
Sequence: LVDTQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRTYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRSLLQHKFSTTPTNIDRFPFLKLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGSWAPMRSKKEVQEVTASYNGVDGCLSSTLEHQVASHNQSSNKNKKVEVIDLTIDSSSDEEEEEPPAKRTCPSLSPTSPLSNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDLQECFVSAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTSLPATNGSSSGSNSSLVSSNSLRESHGHGVASRSSADTASIFGIIPDIISLD
InterPro domains: - IPR036361: SAP domain superfamily (homologous_superfamily) [3-61]
- IPR038654: PINIT domain superfamily (homologous_superfamily) [131-283]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [285-406]
- IPR023321: PINIT domain (domain) [120-284]
- IPR004181: Zinc finger, MIZ-type (domain) [308-395]
- IPR003034: SAP domain (domain) [7-41]
Interaction partners: - Signal transducer and activator of transcription 1
- Small ubiquitin-related modifier 1
- Signal transducer and activator of transcription
- Signal transducer and activator of transcription 3
- SUMO-conjugating enzyme UBC9
- Small ubiquitin-related modifier 3
- Small ubiquitin-related modifier
- Small ubiquitin-related modifier
- Small ubiquitin-related modifier 2
- Androgen receptor
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019904 (protein domain specific binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0019953 (sexual reproduction), GO:0009628 (response to abiotic stimulus), GO:0019222 (regulation of metabolic process), GO:0022402 (cell cycle process), GO:0007049 (cell cycle), GO:0071840 (cellular component organization or biogenesis), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0003008 (system process), GO:0050793 (regulation of developmental process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0051094 (positive regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0048609 (multicellular organismal reproductive process), GO:0007610 (behavior), GO:0048522 (positive regulation of cellular process), GO:0007276 (gamete generation), GO:0045597 (positive regulation of cell differentiation), GO:0044085 (cellular component biogenesis), GO:1903047 (mitotic cell cycle process), GO:0060548 (negative regulation of cell death), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0009314 (response to radiation), GO:0060255 (regulation of macromolecule metabolic process), GO:0009891 (positive regulation of biosynthetic process), GO:0007283 (spermatogenesis), GO:0010941 (regulation of cell death), GO:0031325 (positive regulation of cellular metabolic process), GO:0007611 (learning or memory), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0007632 (visual behavior), GO:0044770 (cell cycle phase transition), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0045595 (regulation of cell differentiation), GO:0031323 (regulation of cellular metabolic process), GO:0016043 (cellular component organization), GO:0050877 (nervous system process), GO:0080090 (regulation of primary metabolic process), GO:0000278 (mitotic cell cycle), GO:0050890 (cognition), GO:0009416 (response to light stimulus), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0044843 (cell cycle G1/S phase transition), GO:0051246 (regulation of protein metabolic process), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:0007612 (learning), GO:0051147 (regulation of muscle cell differentiation), GO:0010468 (regulation of gene expression), GO:0022607 (cellular component assembly), GO:0051149 (positive regulation of muscle cell differentiation), GO:0008542 (visual learning), GO:0044772 (mitotic cell cycle phase transition), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0051247 (positive regulation of protein metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0043933 (protein-containing complex organization), GO:0051252 (regulation of RNA metabolic process), GO:0048232 (male gamete generation), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0042981 (regulation of apoptotic process), GO:0031399 (regulation of protein modification process), GO:0065003 (protein-containing complex assembly), GO:0071824 (protein-DNA complex subunit organization), GO:0043066 (negative regulation of apoptotic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0000082 (G1/S transition of mitotic cell cycle), GO:0051150 (regulation of smooth muscle cell differentiation), GO:1902680 (positive regulation of RNA biosynthetic process), GO:0031401 (positive regulation of protein modification process), GO:0008306 (associative learning), GO:0045893 (positive regulation of DNA-templated transcription), GO:1903320 (regulation of protein modification by small protein conjugation or removal), GO:1903322 (positive regulation of protein modification by small protein conjugation or removal), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0065004 (protein-DNA complex assembly), GO:0033235 (positive regulation of protein sumoylation), GO:0033233 (regulation of protein sumoylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)