wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: adenylate cyclase (EC 4.6.1.1) (M9PBA8)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MNKKNTYKTPYRERFRRCNLEYTNERLWEQSYLKARCKELHLEEEYMKYKIRLMISSLTVFVPMLILLIVALQVIIWSFTEYTKYIYINAIFDLGSLILVTGLLSINFFEDFVIRHRWVMTFTSTLSAYVVVLGDIAFNTYYYYKSNWPLNTLYDVFVLCMIYMFLPIPSSKAAALLAISVSLTYVIYFIHFMAFNEHNVAKYVHGLDIVSIDFFHYLGFNMMGIFFRIMNDTMVRSSFLDRYQFITEEIWLRQARRQESLLLDSILPPQIAKPIQKSIKEKIIQPDNDFYHLGTSRTAENFMSIQIHNDVSILYADLVNYTQLTTTLTVEKLVKVLHDLYARFDLAALSFKVQRIKFLGDCYYCVAGLGESDPDHATMAVSLGISMIANIKEVSVNRSLNIGMRIGVHSGTLFAGVIGKAKLQYDIWGADVNIASRLEATGSPGYVHVSGRTLSSLNAEEYNIYPGTESAQKDPVLQKHPMSTYLLTAIPSLDSDKTISIVEGVPNLDLQTVGSNRKSQILKPNLLSHEMREEFRKMPVGGFKFQFPWSRRERNLKNEKVERDLGIFCVAFKDKSVEWNYLHQPDYIFKYSVALGWGIGCCLIYIQSVNNSDIFYTGVVINIIAFFVLTFLLFICWYKKVCWWHSGQNEHRSYGKLSCAIFHLFEKIQHSFVLRLTVYMMIILCYYMVISLILMSCEKDQYELDIIESKLYNYDMDPFTCFHPWAYTNMMALILGMSYTFARIPFALKTFIGCAEAVVFVLVVCFQYAFIFEHSVTTSPYLKAEIAHSCRVCMMLITMYAKERQSEFNTKMNYKLNLDLQNKQKSADVTNQSIIILLNNILPSHVVLFRSRGISQLYSQTRTLL
InterPro domains: - IPR001054: Adenylyl cyclase class-3/4/guanylyl cyclase (domain) [254-488]
- IPR029787: Nucleotide cyclase (homologous_superfamily) [248-490]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0009975 (cyclase activity), GO:0004016 (adenylate cyclase activity), GO:0016849 (phosphorus-oxygen lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0019953 (sexual reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0007276 (gamete generation), GO:0007283 (spermatogenesis), GO:0048232 (male gamete generation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Forkhead box O4 (A0A096MJF0)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
Sequence: MEPENKKSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPELATEPPEPSEVEPSLGQKAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWMLNPDGGKGGKAPRRRAASMDSSSKLLRGRSKGPKKKPSVLPAPPEGATPRSPLGHFAKWSSSPCPRNREEADVWTTFRPRSSSNASTVSTRLSPMRPESEVLAEEEMPASASSYAGGVPPTLSEDLELLDGLNLASPHSLLSRSNLSSFSLQHPGLAGPLHSYGASLFGPIDGSLSAGEGCFSSSQSLEALLTSDTPPPPADVLMTQVDPILSQAPTLLLLGGMPSSSKLATGVSLCPTPLEGPGPSNLVPTLSVMAPPPVMPGAPIPKVLGTPVLASPTEDFSHDRMPQDLDLDMYMENLECDMDNIISDLMDGEGLDFNFEPDP
InterPro domains: - IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [52-132]
- IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [54-128]
- IPR030456: Fork head domain conserved site 2 (conserved_site) [95-101]
- IPR001766: Fork head domain (domain) [44-140]
- IPR032067: FOXO protein, transactivation domain (domain) [409-448]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding), GO:0005515 (protein binding), GO:1990841 (promoter-specific chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009605 (response to external stimulus), GO:0006950 (response to stress), GO:0007568 (aging), GO:0040017 (positive regulation of locomotion), GO:0040012 (regulation of locomotion), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0009991 (response to extracellular stimulus), GO:2000145 (regulation of cell motility), GO:2000147 (positive regulation of cell motility), GO:0035902 (response to immobilization stress), GO:0030335 (positive regulation of cell migration), GO:0030334 (regulation of cell migration), GO:0031667 (response to nutrient levels), GO:0014910 (regulation of smooth muscle cell migration), GO:0014911 (positive regulation of smooth muscle cell migration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Membrane protein (M protein) (E1 glycoprotein) (Matrix glycoprotein) (Membrane glycoprotein) (K9N7A1)
Organism: Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012) (MERS-CoV) (Betacoronavirus England 1)
Function: Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
Subcellular location: Virion membrane {ECO:0000255|HAMAP-Rule:MF_04202}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_04202}. Host Golgi apparatus membrane {ECO:0000255|HAMAP-Rule:MF_04202, ECO:0000269|PubMed:24318862}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_04202}. Note=Largely embedded in the lipid bilayer. {ECO:0000255|HAMAP-Rule:MF_04202}.
Sequence: MSNMTQLTEAQIIAIIKDWNFAWSLIFLLITIVLQYGYPSRSMTVYVFKMFVLWLLWPSSMALSIFSAVYPIDLASQIISGIVAAVSAMMWISYFVQSIRLFMRTGSWWSFNPETNCLLNVPFGGTTVVRPLVEDSTSVTAVVTNGHLKMAGMHFGACDYDRLPNEVTVAKPNVLIALKMVKRQSYGTNSGVAIYHRYKAGNYRSPPITADIELALLRA
InterPro domains: - IPR002574: M matrix/glycoprotein, coronavirus (family) [1-219]
- IPR044363: M matrix/glycoprotein, MERS-like-CoV (family) [2-218]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0016032 (viral process), GO:0019068 (virion assembly), GO:0019058 (viral life cycle)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0033643 (host cell part), GO:0043657 (host cell), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0030430 (host cell cytoplasm)
Protein: Single-strand DNA-binding protein (P0A3W8)
Organism: Rhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium radiobacter)
Function: Involved in DNA transformation; mediates the nuclear uptake of single-stranded DNA copies of the transferred DNA (T-DNA) element. Binds single-stranded but not double-stranded DNA regardless of nucleotide sequence composition.
Subcellular location: Secreted. Host nucleus. Note=In infected cells, it is found in the nucleus.
Sequence: MDLSGNEKSRPWKKANVSSSTISDIQMTNGENLESGSPTRTEVLSPRLDDGSVDSSSSLYSGSEHGNQAEIQKELSALFSNMSLPGNDRRPDEYILVRQTGQDAFTGIAKGNLDHMPTKAEFNACCRLYRDGAGNYYPPPLAFDKISVPAQLEETWGMMEAKERNKLRFQYKLDVWNHAHADMGITGTEIFYQTDKNIKLDRNYKLRPEDRYVQTERYGRREIQKRYQHELQAGSLLPDIMIKTPKNDIHFVYRFAGDNYANKQFSEFEHTVKRRYGGETEIKLKSKSGIMHDSKYLESWERGSADIRFAEFVGENRAHNRQFPTATVNMGQQPDGQGGLTRDRHVSVEFLMQSAPNSPWAQALKKGELWDRVQLLARDGNRYLSPHRLEYSDPEHFTELMNRVGLPASMGRQSHAASIKFEKFDAQAAVIVINGPELRDIHDLSPENLQNVSTKDVIVADRNENGQRTGTYTSVAEYERLQLRLPADAAGVLGEAADKYSRDFVRPEPASRPISDSRRIYESRPRSQSVNSF
InterPro domains: - IPR009868: VirE2 (family) [13-532]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023057 (negative regulation of signaling), GO:0035821 (modulation of process of another organism), GO:0044068 (modulation by symbiont of host cellular process), GO:0048523 (negative regulation of cellular process), GO:0044403 (biological process involved in symbiotic interaction), GO:0048585 (negative regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0052027 (modulation by symbiont of host signal transduction pathway), GO:0044501 (modulation of signal transduction in another organism), GO:0051701 (biological process involved in interaction with host), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0010646 (regulation of cell communication), GO:0044003 (modulation by symbiont of host process), GO:0009966 (regulation of signal transduction), GO:0052029 (suppression by symbiont of host signal transduction pathway), GO:1902532 (negative regulation of intracellular signal transduction), GO:1902531 (regulation of intracellular signal transduction), GO:0043122 (regulation of I-kappaB kinase/NF-kappaB signaling), GO:0043124 (negative regulation of I-kappaB kinase/NF-kappaB signaling)
Cellular Component (CC): GO:0005575 (cellular component), GO:0044423 (virion component), GO:0019028 (viral capsid)
Protein: Actin-related protein 2/3 complex subunit 1A (SOP2-like protein) (Sid 329) (Q9R0Q6)
Organism: Mus musculus (Mouse)
Function: Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks (By similarity). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (By similarity).
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q92747}. Nucleus {ECO:0000250|UniProtKB:Q8AVT9}.
Sequence: MSLHQFLLEPITCHAWNRDRTQIALSPNNHEVHIYKKNGSQWTKAHELKEHNGHITGIDWAPKSDRIVTCGADRNAYVWSQKDGIWKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFESENDWWVSKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVDEKPASTPWGSKMPFGQLMSEFGGSGTGGWVHGVSFSASGNRLAWVSHDSTVSVADASKSVQVSTLRTEFLPLLSVSFVSENSVVAAGHDCCPMLFNYDDRGCLTFVSKLDVPKQSIQRNMSAMERFRNMDKRATTEDRNTALETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKTLESSIQGLRIM
InterPro domains: - IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [1-370]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [6-361]
- IPR001680: WD40 repeat (repeat) [41-356]
- IPR017383: Actin-related protein 2/3 complex subunit 1 (family) [1-362]
Interaction partners: - Actin-related protein 2/3 complex subunit 3
- Actin-related protein 2/3 complex subunit 2
- Actin-related protein 2/3 complex subunit 5
- Actin-related protein 2/3 complex subunit 4
- Actin-related protein 2/3 complex subunit 5-like protein
- Actin-related protein 2
- Actin-related protein 3
- Actin nucleation-promoting factor WASL
- Actin-related protein 2/3 complex subunit 1B
- Actin nucleation-promoting factor WAS
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0030029 (actin filament-based process), GO:0030036 (actin cytoskeleton organization), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0007010 (cytoskeleton organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005885 (Arp2/3 protein complex), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015629 (actin cytoskeleton)
Protein: Intermediate filament protein ifa-4 (Cel IF A4) (Intermediate filament protein A4) (IF-A4) (P90900)
Organism: Caenorhabditis elegans
Function: Cytoplasmic intermediate filaments provide mechanical strength to cells. Non-essential protein.
Subcellular location: Cytoplasm {ECO:0000250}.
Sequence: MSESEYRSSISVRPTFNRTMQSTATYGSTISSGTSRTLKITEIGGSNLTSGMSPFGGHAASAIRESRTREKKEMSELNDRLASYIEKVRFLEAQNRKMEKDLNLLRGKWGHDSTSVKVMYETELRSAKDLIADSDKERAQLEDQIKKLVEELNNYRNKLHEAERGADVTRKELDNVLGRLGALEAEIELLKRRISLMEESIGHLKRENHRMIDSLHHARNAVEQETLNRIDYQNQVQTLLEECDFIRRIHDSEIHDLLAMASRDTTVENREYFKNELSSAIREIRSEYDHVSNTTRTDIESWYKLKVQEIHTQNSRNCLEQNYAREEVKRLRTTLGDMRGKMADLEGRNLLLEKQIEDLNYQMEEDMRSYEQSLNDKDTSINKLRDESKILMVELQMLIDTKQTLDAEIVIYRKMLDGEENRAGLRQLVEQVVKTTSIHQTKEIESLRVLKGETTSHSSYSRSAKGNIAIQEAEPSGKYIVLENISRRDENIGDWKLRRKIAGKREIVFTFPREFTLRAQKSVKIFARGQGVHSPPDSLVYDLEDSFGTGNDVVTTLYNKEGEDRASHSQRASHT
InterPro domains: - IPR039008: Intermediate filament, rod domain (domain) [69-423]
- IPR016451: Intermediate filament, ifa/ifb (family) [1-575]
- IPR001322: Lamin tail domain (domain) [456-572]
- IPR018039: Intermediate filament protein, conserved site (conserved_site) [409-417]
- IPR036415: Lamin tail domain superfamily (homologous_superfamily) [432-574]
Interaction partners: - Intermediate filament protein ifb-1
- Cysteine-rich protein 1
- Intermediate filament protein ifp-1
- Intermediate filament protein ifc-1
- Intermediate filament protein ifc-2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhesion), GO:0098609 (cell-cell adhesion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0005856 (cytoskeleton), GO:0099513 (polymeric cytoskeletal fiber), GO:0005882 (intermediate filament), GO:0045111 (intermediate filament cytoskeleton)
Protein: Annexin-2 receptor (Annexin II receptor) (AXIIR) (Q3ZCQ2)
Organism: Homo sapiens (Human)
Function: May act as a receptor for annexin II on marrow stromal cells to induce osteoclast formation.
Sequence: MEQHFLGCVKRAWDSAEVAPEPQPPPIVSSEDRGPWPLPLYPVLGEYSLDSCDLGLLSSPCWRLPGVYWQNGLSPGVQSTLEPSTAKPTEFSWPGTQKQQEAPVEEVGQAEEPDRLRLQQLPWSSPLHPWDRQQDTEVCDSGCLLERRHPPALQPWRHLPGFSDCLEWILRVGFAAFSVLWACCSRICGAKQP
InterPro domains: - IPR031449: Annexin-2 receptor (family) [1-193]
Interaction partners: - Annexin A2
- Protein S100-A10
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023056 (positive regulation of signaling), GO:0048522 (positive regulation of cellular process), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010647 (positive regulation of cell communication), GO:0010646 (regulation of cell communication), GO:0080134 (regulation of response to stress), GO:0080135 (regulation of cellular response to stress), GO:0009966 (regulation of signal transduction), GO:0070302 (regulation of stress-activated protein kinase signaling cascade), GO:1902533 (positive regulation of intracellular signal transduction), GO:1902531 (regulation of intracellular signal transduction), GO:0043408 (regulation of MAPK cascade), GO:0032872 (regulation of stress-activated MAPK cascade), GO:0043410 (positive regulation of MAPK cascade), GO:0070304 (positive regulation of stress-activated protein kinase signaling cascade), GO:0046328 (regulation of JNK cascade), GO:0032874 (positive regulation of stress-activated MAPK cascade), GO:0046330 (positive regulation of JNK cascade)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: RH06321p (Q6AWQ6)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: AILNSVVTPSKGLDSEVPTEFLSPMRKPAKRGKRDAAELRELWRTAIRQTIMLNRMETENAMLQARQNENELKRIKLDYEEIVPCDKQLIERWEQIIERNSTQIGNKKDPKVLGHAIRTGVPRSKRGDVWTFLAEQHSMNTAPVDTKRFPNFNTPYHMLLKHLTEHQHAIFIDLGRTFPNHQFYKDPLGLGQLSLFNLLKAYSILDPELGYCQGLGFICGVLLLHCDEANSFQLLKHLMFRRNMRTKYLPDMKKFQLQLYQLSRLVKDHLPDLYVWLDQNDVSPTLYAAPWILTVFSSQFPLGFVARVFDLLFLESSDVIFKFAIALLSVHKQQLLAKDNFEEIMDYLKTVVPKMEHTCMEQIMKLVFSMDIGKQLAEYKVEYNVLQEEITTTNHHLEMLNREKTQNQHLEQQLQFAQSSIAHWRRLVPHSKLRNHAAIAGPVSGANHPNAGSLRWPTGGTQSRPGTTKRGAAHAPAAGRLGPSASEAHIHRTQDRQIRFRQQSLGVSSQGARRADRKRRTWFATKAEEGEDTFF
InterPro domains: - IPR035969: Rab-GAP-TBC domain superfamily (homologous_superfamily) [107-370]
- IPR000195: Rab-GAP-TBC domain (domain) [117-339]
- IPR021785: Domain of unknown function DUF3350 (domain) [26-64]
- IPR050302: Rab GTPase-activating TBC domain-containing protein (family) [60-443]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0050839 (cell adhesion molecule binding), GO:0019899 (enzyme binding), GO:0005178 (integrin binding), GO:0005102 (signaling receptor binding), GO:0051020 (GTPase binding), GO:0031267 (small GTPase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhesion), GO:0033627 (cell adhesion mediated by integrin)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0009986 (cell surface), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Uncharacterized protein C16C4.19 (O94306)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Not known
Sequence: MDQERKLQFLLSIAAETYAISPSLSSHYLRRMFSLLEEWNLETDPKTLLHGCSKCGSLFIFGRNIKLRTISSERKARTDLKKGEVSRLGTNLEINCLVCSYVHEIPLGVPLRLHQSKQALRAKAIAESSSTKLESRKSAHNAKVKQRQRLRASGLNGILDRKKKKDEVAKSTSSLSLQDFMSPI
InterPro domains: - IPR007175: Ribonuclease P subunit, Rpr2/Snm1/Rpp21 (family) [6-100]
Interaction partners: - Probable ribonuclease P protein subunit 1
- Ribonuclease MRP protein subunit rmp1
- Ribonucleases P/MRP protein subunit pop1
- Probable ribonuclease P protein subunit 3
- Ribonucleases P/MRP protein subunit pop3
- Ribonuclease P/MRP protein subunit POP5
- Probable ribonucleases P protein subunit pop8
- Uncharacterized protein C6C3.09
- Ribonucleases P/MRP protein subunit POP7
- Large ribosomal subunit protein uL30C
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0019843 (rRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0010467 (gene expression), GO:0042254 (ribosome biogenesis), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0006397 (mRNA processing), GO:0016071 (mRNA metabolic process), GO:0034470 (ncRNA processing), GO:0006364 (rRNA processing), GO:0034660 (ncRNA metabolic process), GO:0000460 (maturation of 5.8S rRNA), GO:0016072 (rRNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)
Protein: Uncharacterized protein YjiK (P39382)
Organism: Escherichia coli (strain K12)
Function: Not known
Subcellular location: Cell membrane {ECO:0000255|PROSITE-ProRule:PRU00303}; Single-pass membrane protein {ECO:0000305}.
Sequence: MTKSISLSKRISIIVILFAIVAVCTFFVQSCARKSNHAASFQNYHATIDGKEIAGITNNISSLTWSAQSNTLFSTINKPAAIVEMTTNGDFIRTIPLDFVKDLETIEYIGDNQFVISDERDYAIYVISLTPNSEVKILKKIKIPLQDSPTNCGFEGLAYSRQDHTFWFFKEKNPIEVYKVNGLLSSNELHISKDEALQRQFTLDDVSGAEFNQQKNTLLVLSHESRALQEVTLVGEVIGEMSLTKGSRGLSHNIKQAEGVAMDASGNIYIVSEPNRFYRFTPQSSH
InterPro domains: - IPR009722: YjiK/CarP (family) [37-281]
- IPR011042: Six-bladed beta-propeller, TolB-like (homologous_superfamily) [40-286]
Interaction partners: - Lipopolysaccharide core heptose
- Lipopolysaccharide glucosyltransferase WaaG
- Phosphoethanolamine transferase EptC
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0004518 (nuclease activity), GO:0004519 (endonuclease activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0005975 (carbohydrate metabolic process), GO:1901575 (organic substance catabolic process), GO:0044248 (cellular catabolic process), GO:0044262 (cellular carbohydrate metabolic process), GO:0044275 (cellular carbohydrate catabolic process), GO:0009311 (oligosaccharide metabolic process), GO:0016052 (carbohydrate catabolic process), GO:0005984 (disaccharide metabolic process), GO:0046352 (disaccharide catabolic process), GO:0009313 (oligosaccharide catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)