Protein: ABC transporter G family member 5 (ABC transporter ABCG.5) (OsABCG5) (Protein REDUCED CULM NUMBER 1) (White-brown complex homolog protein 5) (OsWBC5) (Q8H8V7)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Essential transporter for growth and development under abiotic stress. Mediates shoot branching by promoting the outgrowth of lateral shoots. Required for salt tolerance via Na/K homeostasis, at least partly by regulating SKC1/OsHKT1;5. Necessary for hypodermal suberization of roots, which contributes to formation of the apoplastic barrier.
Subcellular location: Cell membrane {ECO:0000269|PubMed:25041515}; Multi-pass membrane protein {ECO:0000255}.
Sequence: MSRFVDKLPLFDRRPSPMEEAEGLPRSGYLGQLHHHQYYQPHSNMLPLEQSPPTSTKHTSVTLAQLLKRVNDARSGSSTPISSPRYTIELGGSKPESVSSESDDHHSDDGGSEGQPRALVLKFTDLTYSVKQRRKGSCLPFRRAAADEPELPAMRTLLDGISGEARDGEIMAVLGASGSGKSTLIDALANRIAKESLHGSVTINGESIDSNLLKVISAYVRQEDLLYPMLTVEETLMFAAEFRLPRSLPTREKKKRVKELIDQLGLKRAANTIIGDEGHRGVSGGERRRVSIGVDIIHNPIMLFLDEPTSGLDSTSAFMVVTVLKAIAQSGSVVVMSIHQPSYRILGLLDRLLFLSRGKTVYYGPPSELPPFFLDFGKPIPDNENPTEFALDLIKEMETETEGTKRLAEHNAAWQLKHHGEGRGYGGKPGMSLKEAISASISRGKLVSGATDGTVSVAASDHSAPPPSSSSVSKFVNPFWIEMGVLTRRAFINTKRTPEVFIIRLAAVLVTGFILATIFWRLDESPKGVQERLGFFAIAMSTMYYTCSDALPVFLSERYIFLRETAYNAYRRSSYVLSHTIVGFPSLVVLSFAFALTTFFSVGLAGGVNGFFYFVAIVLASFWAGSGFATFLSGVVTHVMLGFPVVLSTLAYFLLFSGFFINRDRIPRYWLWFHYISLVKYPYEAVMQNEFGDPTRCFVRGVQMFDNTPLAALPAAVKVRVLQSMSASLGVNIGTGTCITTGPDFLKQQAITDFGKWECLWITVAWGFLFRILFYISLLLGSRNKRR
InterPro domains: - IPR013525: ABC-2 type transporter, transmembrane domain (domain) [484-691]
- IPR017871: ABC transporter-like, conserved site (conserved_site) [282-296]
- IPR003593: AAA+ ATPase domain (domain) [167-359]
- IPR043926: ABC transporter family G domain (domain) [339-414]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [150-371]
- IPR003439: ABC transporter-like, ATP-binding domain (domain) [121-382]
- IPR050352: ATP-binding cassette subfamily G transporters (family) [98-774]
Interaction partners: - HECT-type E3 ubiquitin transferase
- HECT-type E3 ubiquitin transferase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0140657 (ATP-dependent activity), GO:0042626 (ATPase-coupled transmembrane transporter activity), GO:0022857 (transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0015399 (primary active transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0033036 (macromolecule localization), GO:0010876 (lipid localization), GO:0051649 (establishment of localization in cell), GO:0046907 (intracellular transport), GO:0006810 (transport), GO:0006869 (lipid transport), GO:0071702 (organic substance transport), GO:0032365 (intracellular lipid transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0031090 (organelle membrane), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0070013 (intracellular organelle lumen), GO:0000139 (Golgi membrane)