Protein: Fibroblast growth factor receptor substrate 2 (D4A244)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Sequence: MGSCCSCPEKDTVPDNHRNKFKVINVDDDGNELGSGVMELTDTELILYTRKRDSVKWHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPVVERNSHQTELEVPRTPRTPTTPGLGAQSLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGEESTHPLLVAEEQVHTYVNTTGVQEERKNRASVHIPPEARVSNAESNTPKEEPSNTEDRDPHVLLKPEGVKFVLGPTPVQKQLMEKEKLEQLGKDQVSGSGASSTEWDTGYDSDERRDVPPVNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQRRPALLNYENLPSLPPVWEARKLSRDEDDNLGPKTPSLNGYHNNLDPMHNYVNTENVTVPASAHKIDCSRRRDCTPTVFNFDIRRPSLEHRQLNYIQVDLEGGSDSDNPQTPKTPTTPLPQTPTRRTELYAVIDIERTAAMSNLQKALPRDDGTSRKTRHNSTDLPM
InterPro domains: - IPR038742: FRS2, PTB domain (domain) [15-106]
- IPR002404: IRS-type PTB domain (domain) [13-115]
- IPR050996: Docking Protein Family (DOK) (family) [34-478]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [2-135]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0048519 (negative regulation of biological process), GO:0050793 (regulation of developmental process), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0051241 (negative regulation of multicellular organismal process), GO:0051239 (regulation of multicellular organismal process), GO:0051093 (negative regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0045596 (negative regulation of cell differentiation), GO:0007186 (G protein-coupled receptor signaling pathway), GO:0070848 (response to growth factor), GO:0071495 (cellular response to endogenous stimulus), GO:0045595 (regulation of cell differentiation), GO:0007166 (cell surface receptor signaling pathway), GO:1905208 (negative regulation of cardiocyte differentiation), GO:0007167 (enzyme-linked receptor protein signaling pathway), GO:0071774 (response to fibroblast growth factor), GO:0051148 (negative regulation of muscle cell differentiation), GO:1905207 (regulation of cardiocyte differentiation), GO:0051147 (regulation of muscle cell differentiation), GO:0071363 (cellular response to growth factor stimulus), GO:0051154 (negative regulation of striated muscle cell differentiation), GO:0007169 (transmembrane receptor protein tyrosine kinase signaling pathway), GO:0051153 (regulation of striated muscle cell differentiation), GO:0044344 (cellular response to fibroblast growth factor stimulus), GO:0008543 (fibroblast growth factor receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0005886 (plasma membrane), GO:0005911 (cell-cell junction), GO:0036056 (filtration diaphragm)