Protein: Homeobox protein HAZ1 (Homeobox protein HOX1A homolog) (Q8H991)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Transcriptional repressor involved in the regulation of gibberrelin (GA) signaling. Binds to the 5'-GATC-3' motif of HD16/EL1 promoter. Functions as a positive regulator of GA signaling by suppressing the expression of HD16/EL1, a negative regulator of GA signaling.
Subcellular location: Nucleus {ECO:0000269|PubMed:21951842}.
Sequence: MDKTTTSDLVLDNDNIGSNAGSAQEPLTTNGKTSGVRNRYKQTVKRGRKGSQISPSKTYPLRSSHSNVRVLRSASKKKNETPIVPTNDNTAVQRVAKKRKRSKPLRPAPSRVLRSTSEKKNKAHNELLNDGAGVQPAEKKRKVGRPPKGGTPKDDYLMIRKRVRYVLNRMNYEQSLIQAYASEGWKGQSLEKIRPEKELERAKVEILRCKSRIREAFRNLDSLLSEGKLDESMFDSAGEISSEDIFCAACGSKDVTLKNDIILCDGICDRGFHQYCLNPPLLAEDIPQGDEGWLCPACDCKIDCIDVLNELQGVKLSIHDSWEKVFPEAASFLNGSKQIDASDLPSDDSADNDYDPTLAQGHKVDEEKSSGEDGGEGLDSDDSSSEDSESSEKEKSKTSQNGRTVDDLGLPSEDSEDGDFDPAGPDSDKEQNDESNSDQSDESDFTSDSDDFCAEIAKSCGQDEISGPSSSQIRTVDRTDGSGFDGEPNAENSNLAFMETELEQDMVLPISSKRQVERLDYKKLYNEAYGKASSDSSDDEEWYGNSTPEKGNLEDSETDSLAESPQGGKGFSRRAPVRYHNNEHTPQNVRPGGSVSDQQTEVLCSNSNGSTAKNRHFGPAINQKLKAHFKEDPYPSRATKENLAQELGLTFNQVTKWFSSTRHYARVAATKKENNIENHTAENNNNTNTVDSIQLRGSNDIVSVDRNDMVSEERTGQSNLNEGTPLRSDTSCGQSVAVTPMVHPENQGNDSSSNVRTPNAKSAEKLIPGLENSDEARRKAVQRELRKMKTGR
InterPro domains: - IPR001356: Homeodomain (domain) [608-672]
- IPR045876: Pathogenesis-related homeodomain protein, PHD finger (domain) [246-298]
- IPR011011: Zinc finger, FYVE/PHD-type (homologous_superfamily) [236-304]
- IPR019787: Zinc finger, PHD-finger (domain) [244-301]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [188-306]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [613-675]
- IPR019786: Zinc finger, PHD-type, conserved site (conserved_site) [247-298]
- IPR001965: Zinc finger, PHD-type (domain) [246-299]
Interaction partners: - Probable lysine-specific demethylase SE14
- Lectin
- Os04g0339800 protein
- MRG family protein, putative, expressed
- Os04g0101300 protein
- Os04g0101100 protein
- Os09g0544500 protein
- ARID transcription factor
- Os02g0708600 protein
- Os02g0708500 protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048522 (positive regulation of cellular process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009891 (positive regulation of biosynthetic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0010468 (regulation of gene expression), GO:1902680 (positive regulation of RNA biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0045893 (positive regulation of DNA-templated transcription), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)