Protein: RNA exonuclease 1 (Q54EC1)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MTNLKNKKIENSSIEVDNNNNNNNNNNNKNQNNKKRTLEISYTNKFQFLDSSDSGGESDTDKEMNRVSLKKKKKSSPISNKLSQDLKKKEQKFKTTNDTVTDYNTNNGGGGVGSNGEIQKPTFSINRNNCTIKDIQDYIVWLMLRFKVPTPNWIFTAMSPLIKKVVVVSIQGISSLMHDKLSLLSGKDHLFSQVFEAKNKVELQFPNYNHIFESLLNVKTCKVQKIDTCEKMRKEIEPISFYLLDDQQLVENGYFTIKDLKDGWVYSNQVKQILNLIKPSNDDDNNNNNQEEDNGASSPTTTTVNSDDDNNDNNNNLINKLNLKVKEMLAIDCEMCRTEGGQLELTRISIVNEQKKVVLNELVLPEKPIIDYLTQYSGITADTLKNVTNRLSDIHAKLEKLVGVDTVLIGHSLENDLKAMKFIHRKIIDTSILYPTGSSGKFSLKYLTKKYLNRIIQSTKHGKLGHDSIEDARAAMDLAQLKIQKGKSFGTRLASMENLFDKINKHEKKSSFIDRLEDIKTFTSQVVSCFNCENDNEVIEKIIKQSSNSSSSDLIFSQLTSLSDHFKSLLPKQFSITNPEENKLTTTTTTTTTTITNPIETIIDSPLLTEKEIKEIHSLDSIEINTTVKQIVRQMELQIKNVYDKLQENSMLLLILGPGPLNDIIRFQGDGNKQKDYYLSVDTAKEGVAFLALK
InterPro domains: - IPR012337: Ribonuclease H-like superfamily (homologous_superfamily) [326-483]
- IPR013520: Ribonuclease H-like domain (domain) [327-488]
- IPR047021: RNA exonuclease REXO1/REXO3/REXO4-like (family) [33-490]
- IPR034922: RNA exonuclease 1-like, exonuclease domain (domain) [329-480]
- IPR036397: Ribonuclease H superfamily (homologous_superfamily) [324-499]
Interaction partners: - Probable oligoribonuclease
- Proliferating cell nuclear antigen
- PAN2-PAN3 deadenylation complex subunit pan3
- Strictosidine synthase family protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016787 (hydrolase activity), GO:0140098 (catalytic activity, acting on RNA), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0004518 (nuclease activity), GO:0004540 (ribonuclease activity), GO:0004532 (exoribonuclease activity), GO:0004527 (exonuclease activity), GO:0008408 (3'-5' exonuclease activity), GO:0016896 (RNA exonuclease activity, producing 5'-phosphomonoesters), GO:0016796 (exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters), GO:0000175 (3'-5'-RNA exonuclease activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0034470 (ncRNA processing), GO:0034660 (ncRNA metabolic process), GO:0006399 (tRNA metabolic process), GO:0008033 (tRNA processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)