Protein: Y-box-binding protein 2-B (Cytoplasmic RNA-binding protein p54) (Frog Y-box protein 2-B) (FRGY2b) (Messenger ribonucleoprotein particle 3) (mRNP3) (P45441)
Organism: Xenopus laevis (African clawed frog)
Function: Putative translation regulator. May be involved in the developmental translational regulation of maternal mRNAs.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:1729676}. Note=Either free or associated with ribonucleoprotein particles.
Sequence: MSEAEPRETEAVTQPEPAPEIHKPDIVPPRNQINKKLLATQVQGTVKWFNVRNGYGFINRNDSKEDVFVHQTAIKKNNPRKFLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVKGSRFAPNRRRFRRQFYRPRADTAGESGGEGVSPEQMSEGEKGEETSPQQRPQRRRPPPFFYRRRFRRGPRPNNQQNQGAEVTDQSENKDPAAPTSEALASGDGQQRPPPRRFQQRFRRPFRPRPPPPQTPEGGDGEAKAEGEPQRQRNRPYVQRRRRQQPPTVQGESKAEPSEHPASEEGTPSDAPTDDGAPVETSEAGVEDTTAPE
InterPro domains: - IPR011129: Cold-shock domain (domain) [43-111]
- IPR050181: Cold shock domain-containing protein (family) [19-300]
- IPR019844: Cold-shock domain, conserved site (conserved_site) [55-74]
- IPR002059: Cold-shock protein Csp, DNA-binding (domain) [41-110]
- IPR012340: Nucleic acid-binding, OB-fold (homologous_superfamily) [32-113]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003723 (RNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048522 (positive regulation of cellular process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009891 (positive regulation of biosynthetic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0010468 (regulation of gene expression), GO:1902680 (positive regulation of RNA biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0045893 (positive regulation of DNA-templated transcription), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1990904 (ribonucleoprotein complex)