Protein: Dumbfounded (KIRRE) (Q9N9Y9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Sequence: MKRMRSSRLLVLPLILVLILTLLLQPIAVHAKSKKNKSSQSSHHGDSSSSSSSSSSSSSSSGSSSAAASSANDESKPKGGDNGGQHFAMEPQDQTAVVGSRVTLPCRVMEKVGALQWTKDDFGLGQHRNLSGFERYSMVGSDEEGDFSLDIYPLMLDDDAKYQCQVGPGPQGEQGIRSRFAKLTVLVPPEAPKITQGDYLVTTEDREIELECVSQGGKPAAEITWIDGLGNVLTKGIEYVKEPLADSRRITARSILKLAPKKEHHNTTFTCQAQNTADRTYRSAKLLLEVKYAPKVIVSVVGGALAGGKIPEGAEVILSCQADANPHELSYRWFINDELMTGDFTTKMIIHNVSRQYHDAIVKCEVVNAVGKSEQSKKLDISFGPVFRQRPVSVEADLGATVSMRCDVAGNPEPEIEWISENSDQVVGVAAELKLKVSSETAGRYFCKAVVNGFPEIGAEATLYVKRAPIITSHKVQFGGVGGRVKIDCLAFSIPKAEHILWSFEGKIINMSSADPDIYIFEEHHLPEGVRAALIIRDSKATHFGKYNCTVLNSYGGDSLVITLLREPGNIPVLLVVMGSMFCVAIILMIVMIIIVYRKRRSRKKPMPADVIPEASRGGDKLNELKSELRSKAYDVEYSEAGGDGLAINLTQSPMPDVQMKGATLGVPLAGPVKFDERFSGDFGGDRYNRQCHIKNLKNQQETAYKGSPQANGYAHYFEYALDYSPPGGEGAAVVVGSGGVGKLKNGGMNSATLPHSAAATVNGGGAGNGGGASLPRNQRHEIQQSQQSNGFLGQPLLQNGIDSRFSAIYGNPYLRTNSSLLPPLPPPSTANPAATPAPPPYHAARHGHAHHANGGLKHFVGGAVITTSPVGNVNINGGGGGGSTPSGGGGVGVGVAAGGSVSGSSSNLTASSNTLAATPLAGGGVGNSGQCAQSPSGQFILSNNGKGHTQKGPLATHV
InterPro domains: - IPR013106: Immunoglobulin V-set domain (domain) [91-185]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [87-564]
- IPR013162: CD80-like, immunoglobulin C2-set (domain) [192-281]
- IPR007110: Immunoglobulin-like domain (domain) [85-563]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [82-565]
- IPR003598: Immunoglobulin subtype 2 (domain) [97-556]
- IPR003599: Immunoglobulin domain subtype (domain) [91-567]
- IPR051275: Cellular adhesion and signaling domain-containing protein (family) [76-765]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0050839 (cell adhesion molecule binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0007155 (cell adhesion), GO:0071840 (cellular component organization or biogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0003008 (system process), GO:0009791 (post-embryonic development), GO:0050793 (regulation of developmental process), GO:0140253 (cell-cell fusion), GO:0006949 (syncytium formation), GO:0050794 (regulation of cellular process), GO:0060142 (regulation of syncytium formation by plasma membrane fusion), GO:0044085 (cellular component biogenesis), GO:0098609 (cell-cell adhesion), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0003014 (renal system process), GO:0061061 (muscle structure development), GO:0009887 (animal organ morphogenesis), GO:0000768 (syncytium formation by plasma membrane fusion), GO:0009790 (embryo development), GO:0016043 (cellular component organization), GO:0002164 (larval development), GO:0051128 (regulation of cellular component organization), GO:0048634 (regulation of muscle organ development), GO:1901861 (regulation of muscle tissue development), GO:0072001 (renal system development), GO:0007520 (myoblast fusion), GO:0048880 (sensory system development), GO:0061318 (renal filtration cell differentiation), GO:0016202 (regulation of striated muscle tissue development), GO:0007423 (sensory organ development), GO:0097205 (renal filtration), GO:0090596 (sensory organ morphogenesis), GO:0008407 (chaeta morphogenesis), GO:0022607 (cellular component assembly), GO:1901739 (regulation of myoblast fusion), GO:0098742 (cell-cell adhesion via plasma-membrane adhesion molecules), GO:0042692 (muscle cell differentiation), GO:0048569 (post-embryonic animal organ development), GO:0007523 (larval visceral muscle development), GO:0007517 (muscle organ development), GO:0034330 (cell junction organization), GO:0009792 (embryo development ending in birth or egg hatching), GO:0048592 (eye morphogenesis), GO:0007157 (heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules), GO:0001654 (eye development), GO:0001700 (embryonic development via the syncytial blastoderm), GO:0007522 (visceral muscle development), GO:0150063 (visual system development), GO:0034329 (cell junction assembly), GO:0061319 (nephrocyte differentiation), GO:0007156 (homophilic cell adhesion via plasma membrane adhesion molecules), GO:0022416 (chaeta development), GO:0051146 (striated muscle cell differentiation), GO:0045216 (cell-cell junction organization), GO:0007043 (cell-cell junction assembly), GO:0048749 (compound eye development), GO:0034332 (adherens junction organization), GO:0014902 (myotube differentiation), GO:0001745 (compound eye morphogenesis), GO:0034333 (adherens junction assembly), GO:0036058 (filtration diaphragm assembly), GO:0036059 (nephrocyte diaphragm assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0045177 (apical part of cell), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0071944 (cell periphery), GO:0098636 (protein complex involved in cell adhesion), GO:0098590 (plasma membrane region), GO:0070161 (anchoring junction), GO:0005886 (plasma membrane), GO:0016324 (apical plasma membrane), GO:0005911 (cell-cell junction), GO:0036056 (filtration diaphragm), GO:0005917 (nephrocyte diaphragm)