wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: GH27120p (Q7K2L7)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Cytoplasm
Sequence: MSYGQGYNPYAQPGGGYAPPPGAFPPQNAQVSPQAQQWFSMVDRDRSGKINASELQAALVNGRGDHFSDNACKLMISMFDNDASGTIDIYEFEKLYNYINQWLQVFKTYDQDSSGHIEEQELTQAFTQMGFRFSPEFINFLVKKSDPQGHKEVSVDQFIVLCVQVQRFTEAFRQRDTQQNGTITIGFEDFLTVAIGCSY
InterPro domains: - IPR051426: Peflin/Sorcin Calcium-Binding (family) [13-197]
- IPR002048: EF-hand domain (domain) [30-159]
- IPR011992: EF-hand domain pair (homologous_superfamily) [29-193]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [43-122]
Interaction partners: - Protein transport protein Sec31A
- ALG-2 interacting protein X
- GEO09647p1
- 26S proteasome non-ATPase regulatory subunit 5
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023056 (positive regulation of signaling), GO:0048522 (positive regulation of cellular process), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010647 (positive regulation of cell communication), GO:0010646 (regulation of cell communication), GO:0080134 (regulation of response to stress), GO:0080135 (regulation of cellular response to stress), GO:0009966 (regulation of signal transduction), GO:0070302 (regulation of stress-activated protein kinase signaling cascade), GO:1902533 (positive regulation of intracellular signal transduction), GO:1902531 (regulation of intracellular signal transduction), GO:0043408 (regulation of MAPK cascade), GO:0032872 (regulation of stress-activated MAPK cascade), GO:0043410 (positive regulation of MAPK cascade), GO:0070304 (positive regulation of stress-activated protein kinase signaling cascade), GO:0046328 (regulation of JNK cascade), GO:0032874 (positive regulation of stress-activated MAPK cascade), GO:0046330 (positive regulation of JNK cascade)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0070971 (endoplasmic reticulum exit site), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Male sterile (3) 76Ca (Q9VW36)
Organism: Drosophila melanogaster (Fruit fly)
Sequence: MAIHEQIDNLNIWWFPRDFCQSRFGEFQRSGTNSCTIISLILADKVAKADRFYHRVSDLPLRGWELFGNAINDGNSVYHNVITTNTPHARNLNLNIPDAIAAIRSQHKMNFRLEEWFYTHMEADPSNPMYNRNVAVQLSRVFQITLQMFQHASVRNNVPTNLFAAIIADSRTVMVTFDFRASIVALFDSHQHGRDAGAVFAQCTLENMDDLLFWFISMLHNVYSSRPSLFEISFLSSQPGVAKNIPPAIQKKIAADLKKPFKMNMPKH
Interaction partners: - AT12577p
- GH20441p
- Probable E3 ubiquitin-protein ligase sinah
- Glutamate dehydrogenase
- LP03867p
- AT14039p
- AT25465p
- Cytosol aminopeptidase
- GH06435p
- GH17939p
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0008233 (peptidase activity), GO:0008234 (cysteine-type peptidase activity), GO:0019783 (ubiquitin-like protein peptidase activity), GO:0101005 (deubiquitinase activity), GO:0004843 (cysteine-type deubiquitinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0006508 (proteolysis), GO:0070646 (protein modification by small protein removal), GO:0070647 (protein modification by small protein conjugation or removal), GO:0016579 (protein deubiquitination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0140513 (nuclear protein-containing complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031519 (PcG protein complex), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Bomanin short 4 (Q8SYA4)
Organism: Drosophila melanogaster (Fruit fly)
Subcellular location: Secreted
Sequence: MRFFAIVTVFVLGLLALANAIPLSPDPGNVIINGDCVNCNVRGGK
InterPro domains: - IPR013172: Bomanin (family) [1-40]
Interaction partners: - Bomanin Short 6
- Bomanin Tailed 2
- Bomanin bicipital 2, isoform A
- Bomanin tailed 1
- Bomanin Bicipital 1
- Daisho1
- Bomanin Short 5
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009617 (response to bacterium), GO:0043207 (response to external biotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: t-SNARE coiled-coil homology domain-containing protein (Q54NB2)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Membrane; Single- pass type IV membrane protein
Sequence: MADLQENEMDFEKIVREVEIGIKDLSKNKRGIEARGGAELLRNRIGRAKQILRSYKLDFRELAKNEQKPYQDKANQYEEQIKTLENDLNWAEKNSENGGGGGGSGGNNSQSIDTEYQETMQKAKKIQQQDIDTTHRILSEVGQINEVGTSTLEEMAVQEEQMKRIQKDMEEIDGNLKLATRQMRAFARKMATDKLIMGLVLLIVAAIIFVIVYSIVKPKSKTVQQNVTGSTQ
InterPro domains: - IPR044766: NPSN/SNAP25-like, N-terminal SNARE domain (domain) [121-184]
- IPR000727: Target SNARE coiled-coil homology domain (domain) [124-186]
- IPR007705: Vesicle transport v-SNARE, N-terminal (domain) [1-89]
Interaction partners: - t-SNARE coiled-coil homology domain-containing protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport), GO:0061024 (membrane organization), GO:0061025 (membrane fusion), GO:0006909 (phagocytosis), GO:0006897 (endocytosis), GO:0010324 (membrane invagination), GO:0099024 (plasma membrane invagination), GO:0006911 (phagocytosis, engulfment)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0031201 (SNARE complex), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043228 (non-membrane-bounded organelle), GO:0005773 (vacuole), GO:0043227 (membrane-bounded organelle), GO:0000323 (lytic vacuole), GO:0030139 (endocytic vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0000331 (contractile vacuole), GO:0098588 (bounding membrane of organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0012506 (vesicle membrane), GO:0010008 (endosome membrane), GO:0031982 (vesicle), GO:0030659 (cytoplasmic vesicle membrane), GO:0005764 (lysosome), GO:0097708 (intracellular vesicle), GO:0045335 (phagocytic vesicle), GO:0062159 (contractile vacuole complex), GO:0005767 (secondary lysosome), GO:0032010 (phagolysosome)
Protein: Nematode cuticle collagen N-terminal domain-containing protein (O16787)
Organism: Caenorhabditis elegans
Sequence: MEPSNIWRTSTIVGSVVSTFAVLTVIIGLPLMHNHVQKVTTLMLTEVELCKTESQDIWKQMKFSRMAPNRTKRQSPYGNYGASGSGSCCACTQGSPGPRGQPGDDGEPGRDGFPGREGDNGIAGKYLPAPPPGTNACQKCPTGAPGPPGLPGPKGPRGPAGIEGKPGRLGEDNRPGPPGPPGVRGEPGSPGEKGPTGDRGKVLNGAPPGPTGPPGKVGPRGLSGGKGHDGKPGLGGQPGVRGAVGARGDAGNPGLPGPQGPKGEPGNPGTCHHCQNRAPAPSEAPGKAPPPPQDYTRPAPESYPSAPNGQYLWIH
InterPro domains: - IPR008160: Collagen triple helix repeat (repeat) [143-201]
- IPR002486: Nematode cuticle collagen, N-terminal (domain) [11-61]
Interaction partners: - Nematode cuticle collagen N-terminal domain-containing protein
- Col_cuticle_N domain-containing protein
- DumPY: shorter than wild-type
- Osmotic avoidance abnormal protein 8
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0042302 (structural constituent of cuticle)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0042303 (molting cycle), GO:0042335 (cuticle development), GO:0018996 (molting cycle, collagen and cuticulin-based cuticle), GO:0042338 (cuticle development involved in collagen and cuticulin-based cuticle molting cycle), GO:0040002 (collagen and cuticulin-based cuticle development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062023 (collagen-containing extracellular matrix), GO:0060102 (collagen and cuticulin-based cuticle extracellular matrix)
Protein: Zinc carboxypeptidase A 1 (D2A3Y2)
Organism: Tribolium castaneum (Red flour beetle)
Function: Involved in the digestion of the blood meal
Subcellular location: Secreted
Sequence: MNLVTTFTFLLLLSLNQILADEKVRYDNFQVYRLTPRSQKAVQALRELEENGYDFWTSVRGVNQPVDVMVPPHYKHRFNDFIRLNEFDAQIYIPDVQKLIDNERPQTRKSVGLEWTDYHTLDEINDWLKDLASTNDNIELVTAGKTYEGRDILGVKVSFKAGNENRTVFIESNIHAREWISSAVTTWMLNEILTSKDSEVRQVAESHDWYFVPVFNPDGFVYTHTTDRLWRKTRVPYSSCYGADPNRNWDYHFNDGGASPSPCSETYCGPKAFSEPTTKSLSEFITTIAPKLQAYIAFHSYSQLLLLPYGYTSKHLENYQELYDVGVKAATSLAKRYGTKYEVGNIVDVLYVASGGSMDWVKGTFGTRITYTYELRDTGRYGFVLPPDQIIPTAEETFDSLVTILQEFDKS
InterPro domains: - IPR057247: Zinc carboxypeptidases, zinc-binding region 2 (binding_site) [299-309]
- IPR003146: Carboxypeptidase, activation peptide (domain) [32-103]
- IPR000834: Peptidase M14, carboxypeptidase A (domain) [117-408]
- IPR036990: Metallocarboxypeptidase-like, propeptide (homologous_superfamily) [23-112]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0043167 (ion binding), GO:0016787 (hydrolase activity), GO:0043169 (cation binding), GO:0008233 (peptidase activity), GO:0046872 (metal ion binding), GO:0008237 (metallopeptidase activity), GO:0008238 (exopeptidase activity), GO:0046914 (transition metal ion binding), GO:0004180 (carboxypeptidase activity), GO:0008235 (metalloexopeptidase activity), GO:0004181 (metallocarboxypeptidase activity), GO:0008270 (zinc ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0006508 (proteolysis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: General transcription factor 3C polypeptide 3-like Protein (A0A139WDX4)
Organism: Tribolium castaneum (Red flour beetle)
Sequence: MDEAPPDALILPFDDDQPGTSTLTDSDSDSSTSSLSDDSPKKTTRAPRRQATKLDPNLKGLMGEANVRYARGDIETAQKMCFEVMRQVPDAYEPYLTLAQIFENTDSTKYEGYLAIASCLYPQDSGIWCRLAELNIHNEKYKEAVSYYSKAIRASPRNMGLHLKRLELVEQIGDVRFALACKKHMANKLPRAQHQNIIELCKEVAKHYHEEKNYVKALEVLKIPFKRIPKRVTQDLVNMMLELLLLTDRFTECLDIFIQHCNFTFEITVNEDNTIAIDSYVMPPSIQIDLKVKFIVCLIKLKSFHLVPPLIDSMIREENVEEIGDLYLDVAEDLMATNMSLEALKLLVPLVKSTTYNLAAVWLKYAECLYNCDMLEQAVEAYFTVMTMAPQHVEVLYPLAMTLLKLNKKSEALEVLSQDLSTNKLDVAVLIERMKLLRQIDDIEEYWKCAELLLSRHCVAVKYPEEARVVITTSYTVNEKVKKIRDMRRFRGDLMPVESGFEKEIQLFALFSTIYNNDTFHGYNLIRNVVTSDSHRHNTLAWNLFNIVLKNTDDIRHNRFISRLQERIPDIHCLQAIEANYSLTTNSNLAIKFYMREFRKLKLPYFALILGVILLQGYSKRKAVEDRKKLAEIASYLFLYYAKNRSKDAQQEIYYNLGRMYHQLGVMYLAQNYYLKVLEIEEKEPSEILGLRYEAAFNLHLIYKNSGNFTAARNVLIKNITI
InterPro domains: - IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [45-722]
- IPR039340: Transcription factor Tfc4/TFIIIC-102/Sfc4 (family) [42-457]
- IPR019734: Tetratricopeptide repeat (repeat) [58-684]
Interaction partners: - General transcription factor 3C polypeptide 5-like Protein
- Myb-like domain-containing protein
- Uncharacterized protein
- Transcription factor IIIB 90 kDa subunit-like Protein
- Transcription factor IIIB 90 kDa subunit-like Protein
- Peptidase C50 domain-containing protein
- Cleavage and polyadenylation specificity factor subunit 2
- Cleavage and polyadenylation specificity factor subunit 1-like Protein
- C2H2-type domain-containing protein
- Protein CLP1 homolog
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0019222 (regulation of metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0070647 (protein modification by small protein conjugation or removal), GO:0032446 (protein modification by small protein conjugation), GO:0016567 (protein ubiquitination), GO:0000209 (protein polyubiquitination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Serine/threonine-protein kinase 11-interacting protein-like Protein (D6X430)
Organism: Tribolium castaneum (Red flour beetle)
Subcellular location: Cytoplasm
Sequence: MEGNQMCILAAQLRGSANNKSNILTLSTRTLDTILSSFELLEEQSTSFHVKQPHNFKAELLRDLQYLSNYIQETKTLKLYIDSYDDTPEIDITKFRKLISLELSKVDVNTVKGLQLLRSQLQKLSCHKTQNNLSDILINCGGDKSRALCWNELKEAACTGNNIVELDLSLECAPWLHTLDLSHNEITNFEALSCLVNLKYLNLSYNRLEGVSVLRGQVCNRLQNLILKNNFIEDIAGLRALTNLWVLDLSNNCLVDHKSLIALSHLAALQWLNLQSNPLSFHPNHRNRTASYLHVNTATTHFVLNSAVLSKNEKKLVGSYYPLQMRTNSFSTDSLSLTTEKARRVRHVVIEEENTVRESSIPSLPPTPKQYLETKKQIEDLHEKFGESWLNSQSGLLDVLGLESFSLPLSTSPYEADFTIYSGDFTQEQEIAKGTVVEPPDQINEEYEKKIEAIPDEPDIEGEESIYLATVRTETEPIFIVIGQTHLSERECSTGNEREKWHLDSITNCEILDEGLTTVQIDFETMRKSRKQRIYVFEDEIEAFVACIKNKINTRQPKKEDDVKYQCMKCSTVFGRVKNESILGEAAVKCPSCDSTLVVEEV
InterPro domains: - IPR057292: Serine/threonine-protein kinase 11-interacting protein, PH domain (domain) [473-540]
- IPR001611: Leucine-rich repeat (repeat) [175-279]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [151-316]
- IPR025875: Leucine rich repeat 4 (repeat) [174-214]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0009408 (response to heat), GO:0009266 (response to temperature stimulus), GO:0033554 (cellular response to stress), GO:0034605 (cellular response to heat)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0031090 (organelle membrane), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098827 (endoplasmic reticulum subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0005789 (endoplasmic reticulum membrane)
Protein: Uncharacterized protein (D6WQX0)
Organism: Tribolium castaneum (Red flour beetle)
Subcellular location: Cytoplasm
Sequence: MEKQMSEELLVPLSSDECGHSGGDPDSDEDVITNYHISSLDMLPRPGPLPTISVTPHSPASKIYPVLEDSLQQVRELHESVQHMRNVTIPDTYIPNSKDLAIALNPILSQMARLSSSCPTLNEANQDMDLLGGSLGSSPVHQNRKGSTQDWLCQPETQRRRSWSALEDLTIKDKAKHTRQRSISLSSMESEADESSFIDNVDGSTTKLLGPDAPAVLRHRNARGSGGATSTHSLNEADLQNDFNKIKAKREAEQRLLPQRLPLQKSISTPSIIAVRDLAPEPILAGAQPTLPMGRPSGTESETEEEGSRSGQARYSHSTHLPYVSFEGHSEKRRKRGSLFFRKKKDKNKKVAHQWVSACYGSSQICDVCAKHLSNKPALYCECCGTTVHQNTCKDNIAECNKPKSTKNSNKMSGFGVPNSKNSFSKRGSASMPGNVNSTSNSQILCDDKDSDLHGHYDGTSFPDDVPLVPLEFLSDSPITAAELCADLSLGLHENEPDSWTPHVGKEIARKLKEKEVKRQEHIYEFILTEKHHCMTLLVMQKVFVEGLQKYFQLGANVERMFPRLADLTELHLGLLSRLRQRQREGPVVSTIADILLEQFSNTNASKLKSAYGEFCSRHRDAVELYKYYLQNDARFGQFVRHCQANPLLKKKGIPECILFITQRLTKYPLLIEPLIKTSKENKKEQDILHKALALIKEILVEVDAQVAEKEKEDRKLEIYNRIDAKSYTVHRDHKFKKSDILQGNRSLKFEGVAMLMQGRGKMQIVLVIVLSDVLFFLQENSHKYSFFTPDNKAGVVSLQKLLVREKAGQDSRGIYLISSNPADPEMFELKVHKPKDKQIWIHAIREAVQSCPEDDEDSSVLSAEERQSLLNAKQIRHFVGLLRQKDIEQALLLEEKMSLQLKLLSAAGIDPPSPSSYRQLVSENVDTGQMWKEVLTAVQEVNRLVSSLYTTGTNLSRSVSSAGEHQSEAYVSPILPKRAETFGGFDNPNQPPLKVLGKKNHSSGGTPVATPEVETVKPGDSKLFEKLPYRNYVIPTTIGSSNNLNMENSQQLTAPPDAPALLSLGREQQYTAVKLSHYVYTLLCIISQLMTTNESYQAQLNALKVGGEGARQYRHNQQLEELRNLQDKLSGEKAAWIATRDQEAKELEEKKAELLKLQEQIRVEQEDIKEQREQLFRKMEKLTNQGLIISPNVGALSLTGQLDDCKDSSEDSPQSDSSTSIASSASGQNSQSTMEKKKDTNKWSKNSLTKSQLPMNLISTTNQQKVQQNVQVKQQIPLKLASRLSSSGPLAGPTGTPQILPLKLSQDEKVRRTSTSGYQRLSPPSGETTPTTSHSHTRTGSSPASMQVSPPGPAPAQKGARQNFPKIGDEEVIYF
InterPro domains: - IPR011993: PH-like domain superfamily (homologous_superfamily) [726-855]
- IPR000219: Dbl homology domain (domain) [518-706]
- IPR001849: Pleckstrin homology domain (domain) [747-852]
- IPR051632: Rho guanine nucleotide exchange factor (family) [69-1376]
- IPR041020: ARHGEF1-like, PH domain (domain) [734-850]
- IPR002219: Protein kinase C-like, phorbol ester/diacylglycerol-binding domain (domain) [352-400]
- IPR035899: Dbl homology (DH) domain superfamily (homologous_superfamily) [492-725]
- IPR046349: C1-like domain superfamily (homologous_superfamily) [336-401]
Interaction partners: - Rho1
- Ras-like GTP-binding protein Rho1
- Ras-like GTP-binding protein Rho1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007017 (microtubule-based process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0000226 (microtubule cytoskeleton organization), GO:0006996 (organelle organization), GO:0007010 (cytoskeleton organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)
Protein: Transmembrane protein 188 (D6WGC4)
Organism: Tribolium castaneum (Red flour beetle)
Subcellular location: Cytoplasm. Nucleus membrane; Multi-pass membrane protein
Sequence: MSLEQTACEDIISDLKAFERRLTEVIACLHPSTIRWRIVLIVVSICIATGAGQWLMDPETRIVPLSQSLTNHPFFIVSTIMFLIILCLGVHKRVIAASIITSRTREVLNDFNMSCDDSGKLILRPRPTNIT
InterPro domains: - IPR019168: Nuclear envelope phosphatase-regulatory subunit 1 (family) [9-129]
Interaction partners: - CTD nuclear envelope phosphatase 1 homolog
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0016032 (viral process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0019048 (modulation by virus of host process), GO:0044403 (biological process involved in symbiotic interaction), GO:0035821 (modulation of process of another organism), GO:0051701 (biological process involved in interaction with host), GO:0044003 (modulation by symbiont of host process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:1902494 (catalytic complex), GO:0005737 (cytoplasm), GO:0098796 (membrane protein complex), GO:0012505 (endomembrane system), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0005783 (endoplasmic reticulum), GO:1903293 (phosphatase complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0008287 (protein serine/threonine phosphatase complex)
Protein: Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase (D2A2P0)
Organism: Tribolium castaneum (Red flour beetle)
Subcellular location: Golgi apparatus membrane; Single- pass type II membrane protein
Sequence: MKYKRFAYLFVGLGVIVVIWKLSVLETSVSNLKTLPQALDLHKDQLELTQRQLMIFEQIHKKTNYFRNYPVIYAVTPTYWRHVQKAELTRISQTLQLVPNVHWIVVEDSDYKTDLVRNLLTESDLIYTHLNAKTPPFEKLKDKDPRWKRHRGVEQRNTALKWLRENLKLGKDKGVVYFMDDDNTYNVRVFQEMNKIKTVGVWPVGLVGGLNAETPVLDKKTGKVMGYRSGWRPDRPFAIDMAGFAINLDLILSRTDAVFSYKMEKGYQESEFLSYFTTKEQLEPLADNCTKVYVWHTRTEKPVVNGIVPGLEV
InterPro domains: - IPR029044: Nucleotide-diphospho-sugar transferases (homologous_superfamily) [70-307]
- IPR005027: Glycosyl transferase, family 43 (family) [55-302]
Interaction partners: - Hexosyltransferase
- Hexosyltransferase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0008194 (UDP-glycosyltransferase activity), GO:0015020 (glucuronosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:0005975 (carbohydrate metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0000139 (Golgi membrane), GO:0043231 (intracellular membrane-bounded organelle)