Protein: Alpha-actinin, sarcomeric (Q9XVU8)
Organism: Caenorhabditis elegans
Function: Not known
Sequence: MVDYYQQPPSYHQPGYDYTQQEEEWDREGLLDPAWEKQQKKTFTAWCNSHLRKAGTSIDTIEEDFRNGLKLMLLLEVISGEPLPKPDRGKMRFHKIANVNKALEYIESKGVKLVSIGAEEIVDGNVKMTLGLIWTIILRFAIQDINVEELSARDGLLLWCQRKTAPYNNVNVQNFHNSWKDGLAFCALIHRHRPDLLDYSQLHKGDPIHNLNLAFDIAEKHLDIPKMLDAEDMANSQPDEKAVMTYVSCYYHYFSGMRKAETAANRICRVLKVNQENEKMMEDYENLASDLLAWINRWMPWLANRSTDDTLQQAQQKLEDYRNYRRREKPPRIEDKGRLETLFNTLQTRLRLSNRPAFLPRDGHLIKDINAAWAGLEDSEKGFEEWLLSEIMRLERLEHLAEKFRRKCALHEEWAHGKEDALRSNDWRSCGLYKIKALRKRHEAFESDLGAHQDRVEQIAAIARELNNLRYPDIGPINARCQAICSQWDRLGQLSSKRRETLEDAERIAERLDSLYLDFAKRAAPFNNWLDGAREDLADLVIVHEMREIEELVNAHDQFKSTLGDADREFSSINQIEHEVEHLVTSHGLDRELLRNPYTDLSASDIRRKWGEVQNSVPRRDSQLQAELKRQQNNERLRTIFAEKANQVGPWLERELEQVLAIGLGGRGRLEDAIQQLRSIQRNVLGYKPNLDELERVHQEMQENFVFENRKSRYSMESLRVGWETLLTSINKTINEFENQVLLRDSKGISEEQIAEFRASFSHFDKERAGLDPEQLRSCLISVGYTIRPGREGDAELHRVLAHVDPNRMGRVPFEAFLDFMTKENSDQDTVEQMIDSFRILASGKTFITADELERELPRDQAAYCMARMAPSREPGAPPRSFDYVTFSRSLYSQ
InterPro domains: - IPR036872: CH domain superfamily (homologous_superfamily) [24-264]
- IPR001589: Actinin-type actin-binding domain, conserved site (conserved_site) [39-137]
- IPR018159: Spectrin/alpha-actinin (repeat) [400-628]
- IPR011992: EF-hand domain pair (homologous_superfamily) [737-857]
- IPR002048: EF-hand domain (domain) [752-827]
- IPR014837: EF-hand, Ca insensitive (domain) [827-892]
- IPR002017: Spectrin repeat (repeat) [280-625]
- IPR001715: Calponin homology domain (domain) [37-255]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0051641 (cellular localization), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0030029 (actin filament-based process), GO:0051050 (positive regulation of transport), GO:0033036 (macromolecule localization), GO:0048522 (positive regulation of cellular process), GO:0010171 (body morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0051049 (regulation of transport), GO:0070727 (cellular macromolecule localization), GO:0009790 (embryo development), GO:0016043 (cellular component organization), GO:0060627 (regulation of vesicle-mediated transport), GO:0051130 (positive regulation of cellular component organization), GO:0045807 (positive regulation of endocytosis), GO:0051128 (regulation of cellular component organization), GO:0030036 (actin cytoskeleton organization), GO:0030100 (regulation of endocytosis), GO:0030866 (cortical actin cytoskeleton organization), GO:0010172 (embryonic body morphogenesis), GO:0008104 (protein localization), GO:0006996 (organelle organization), GO:0007010 (cytoskeleton organization), GO:0030865 (cortical cytoskeleton organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0036379 (myofilament), GO:0099080 (supramolecular complex), GO:0055120 (striated muscle dense body), GO:0030017 (sarcomere), GO:0005737 (cytoplasm), GO:0043292 (contractile fiber), GO:0043229 (intracellular organelle), GO:0005865 (striated muscle thin filament), GO:0043228 (non-membrane-bounded organelle), GO:0099081 (supramolecular polymer), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0030016 (myofibril), GO:0005856 (cytoskeleton), GO:0015629 (actin cytoskeleton)