Protein: Cytochrome b5 isoform B (AtCb5-B) (Cytochrome b5 isoform 2) (Cytochrome b5 isoform E) (AtCb5-E) (O48845)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases, including fatty acid desaturases.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000269|PubMed:19054355, ECO:0000269|PubMed:22773744}; Single-pass membrane protein {ECO:0000269|PubMed:19054355, ECO:0000269|PubMed:22773744}; Cytoplasmic side {ECO:0000269|PubMed:19054355, ECO:0000269|PubMed:22773744}.
Sequence: MGDEAKIFTLSEVSEHNQAHDCWIVINGKVYNVTKFLEDHPGGDDVLLSSTGKDATDDFEDVGHSESAREMMEQYYVGEIDPTTIPKKVKYTPPKQPHYNQDKTSEFIIKLLQFLVPLAILGLAVGIRIYTKSG
InterPro domains: - IPR050668: Cytochrome b5 (family) [4-130]
- IPR001199: Cytochrome b5-like heme/steroid binding domain (domain) [5-81]
- IPR018506: Cytochrome b5, heme-binding site (binding_site) [36-43]
- IPR036400: Cytochrome b5-like heme/steroid binding domain superfamily (homologous_superfamily) [2-93]
Interaction partners: - NADH--cytochrome b5 reductase 1
- NADH-cytochrome b5 reductase-like protein
- Dihydroceramide fatty acyl 2-hydroxylase FAH1
- Dihydroceramide fatty acyl 2-hydroxylase FAH2
- Bax inhibitor 1
- Very-long-chain aldehyde decarbonylase CER1
- Probable lysophospholipase BODYGUARD 1
- Very-long-chain aldehyde decarbonylase CER3
- Probable steroid-binding protein 3
- Ergosterol biosynthetic protein 28
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006066 (alcohol metabolic process), GO:0044107 (cellular alcohol metabolic process), GO:0016125 (sterol metabolic process), GO:1902652 (secondary alcohol metabolic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0008204 (ergosterol metabolic process), GO:0008202 (steroid metabolic process), GO:0097384 (cellular lipid biosynthetic process), GO:1901617 (organic hydroxy compound biosynthetic process), GO:0044108 (cellular alcohol biosynthetic process), GO:0046165 (alcohol biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0016128 (phytosteroid metabolic process), GO:0006696 (ergosterol biosynthetic process), GO:0006694 (steroid biosynthetic process), GO:0016126 (sterol biosynthetic process), GO:0016129 (phytosteroid biosynthetic process), GO:1902653 (secondary alcohol biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle)