wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: ATP sulfurylase 1, chloroplastic (AtPS1) (EC 2.7.7.4) (Q9LIK9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Mediates selenate (Se) reduction, and promotes Se and sulfur (S) uptake and assimilation.
Subcellular location: Plastid, chloroplast stroma {ECO:0000269|PubMed:18431481, ECO:0000269|PubMed:8058839}.
Sequence: MASMAAVLSKTPFLSQPLTKSSPNSDLPFAAVSFPSKSLRRRVGSIRAGLIAPDGGKLVELIVEEPKRREKKHEAADLPRVELTAIDLQWMHVLSEGWASPLGGFMRESEFLQTLHFNSLRLDDGSVVNMSVPIVLAIDDEQKARIGESTRVALFNSDGNPVAILSDIEIYKHPKEERIARTWGTTAPGLPYVDEAITNAGNWLIGGDLEVLEPVKYNDGLDRFRLSPAELRKELEKRNADAVFAFQLRNPVHNGHALLMTDTRRRLLEMGYKNPILLLHPLGGFTKADDVPLDWRMKQHEKVLEDGVLDPETTVVSIFPSPMHYAGPTEVQWHAKARINAGANFYIVGRDPAGMGHPVEKRDLYDADHGKKVLSMAPGLERLNILPFRVAAYDKTQGKMAFFDPSRPQDFLFISGTKMRTLAKNNENPPDGFMCPGGWKVLVDYYESLTPAGNGRLPEVVPV
InterPro domains: - IPR002650: Sulphate adenylyltransferase (family) [53-445]
- IPR024951: Sulphate adenylyltransferase catalytic domain (domain) [223-444]
- IPR025980: ATP-sulfurylase PUA-like domain (domain) [51-213]
- IPR014729: Rossmann-like alpha/beta/alpha sandwich fold (homologous_superfamily) [218-451]
- IPR015947: PUA-like superfamily (homologous_superfamily) [51-219]
Interaction partners: - Adenylyl-sulfate kinase 1, chloroplastic
- Adenylyl-sulfate kinase 4, chloroplastic
- Adenylyl-sulfate kinase 2, chloroplastic
- Adenylyl-sulfate kinase 3
- 5'-adenylylsulfate reductase 1, chloroplastic
- 5'-adenylylsulfate reductase 2, chloroplastic
- 5'-adenylylsulfate reductase 3, chloroplastic
- Assimilatory sulfite reductase
- Bifunctional adenosine 5'-phosphosulfate phosphorylase/adenylylsulfatase HINT4
- Sulfite oxidase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016779 (nucleotidyltransferase activity), GO:0070566 (adenylyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006790 (sulfur compound metabolic process), GO:0000103 (sulfate assimilation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009532 (plastid stroma), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009570 (chloroplast stroma), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Perilipin 4 (A0A0J9YXN7)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Lipid droplet {ECO:0000256|ARBA:ARBA00004502}.
Sequence: MSAPDEGRRDPPKPKGKTLGSFFGSLPGFSSARNLVANAHSSARARPAADPTGAPAAEAAQPQAQVAAHPEQTAPWTEKELQPSEKQMVSGAKDLVCSKMSRAKDAVSSGVASVVDVAKGVVQGGLDTTRSALTGTKEVVSSGVTGAMDMAKGAVQGGLDTSKAVLTGTKDTVSTGLTGAVNVAKGTVQAGVDTTKTVLTGTKDTVTTGVMGAVNLAKGTVQTGVETSKAVLTGTKDAVSTGLTGAVNVARGSIQTGVDTSKTVLTGTKDTVCSGVTGAMNVAKGTIQTGVDTSKTVLTGTKDTVCSGVTGAMNVAKGTIQTGVDTSKTVLTGTKDTVCSGVTGAMNVAKGTIQTGVDTTKTVLTGTKNTVCSGVTGAVNLAKEAIQGGLDTTKSMVMGTKDTMSTGLTGAANVAKGAMQTGLNTTQNIATGTKDTVCSGVTGAMNLARGTIQTGVDTTKIVLTGTKDTVCSGVTGAANVAKGAVQGGLDTTKSVLTGTKDAVSTGLTGAVNVAKGTVQTGVDTTKTVLTGTKDTVCSGVTSAVNVAKGAVQGGLDTTKSVVIGTKDTMSTGLTGAANVAKGAVQTGVDTAKTVLTGTKDTVTTGLVGAVNVAKGTVQTGMDTTKTVLTGTKDTIYSGVTSAVNVAKGAVQTGLKTTQNIATGTKNTFGSGVTSAVNVAKGAAQTGVDTAKTVLTGTKDTVTTGLMGAVNVAKGTVQTSVDTTKTVLTGTKDTVCSGVTGAANVAKGAIQGGLDTTKSVLTGTKDAVSTGLTGAVKLAKGTVQTGMDTTKTVLTGTKDAVCSGVTGAANVAKGAVQMGVDTAKTVLTGTKDTVCSGVTGAANVAKGAVQTGLKTTQNIATGTKNTLGSGVTGAAKVAKGAVQGGLDTTKSVLTGTKDAVSTGLTGAVNLAKGTVQTGVDTSKTVLTGTKDTVCSGVTGAVNVAKGTVQTGVDTAKTVLSGAKDAVTTGVTGAVNVAKGTVQTGVDASKAVLMGTKDTVFSGVTGAMSMAKGAVQGGLDTTKTVLTGTKDAVSAGLMGSGNVATGATHTGLSTFQNWLPSTPATSWGGLTSSRTTDNGGEQTALSPQEAPFSGISTPPDVLSVGPEPAWEAAATTKGLATDVATFTQGAAPGREDTGLLATTHGPEEAPRLAMLQNELEGLGDIFHPMNAEEQAQLAASQPGPKVLSAEQGSYFVRLGDLGPSFRQRAFEHAVSHLQHGQFQARDTLAQLQDCFRLIEKAQQAPEGQPRLDQGSGASAEDAAVQEERDAGVLSRVCGLLRQLHTAYSGLVSSLQGLPAELQQPVGRARHSLCELYGIVASAGSVEELPAERLVQSREGVHQAWQGLEQLLEGLQHNPPLSWLVGPFALPAGGQ
InterPro domains: - IPR004279: Perilipin (family) [1157-1366]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0043229 (intracellular organelle), GO:0005886 (plasma membrane), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005811 (lipid droplet)
Protein: Kazal-like domain-containing protein (Q9VYH8)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MTAFLVSIGFALLAGARAWDYGVPYYPAPHYFEQQQPYDLPCPPSGPESLVCAGAPGAQPSTFPSPCEVQRFRALTGINWEIIHENRCETLEVCPDNCQDQYNPVCGKYKDTRRNFRSECELQLVKCRTGHPWRKQHDGPCESRYPVPQSPRVQNYNPYAINPYQPNVGSRGAYGSQGPYGSQGPYGSQGPYGPQSPPQPYPSSSFVSPRPNYEAPIYQPYQISWENLPTEYAGTSKPYPNPTYETTPTTTSTTASTTTSTTTSTTTTTTTPKTTTDKITTTPQPGDSETTEASTVTPNPRRNIKVNAVIEDTPKPSTTTGQPEESTESSSTESSVTTTPLKKYITTASPQHATTTARPSKPSLSINAVQVPEQEAEKTTSTEPTTTYKSFNSYNSYASYTTTEAPVTEDTTKVPVDEIIKINKVQISAENTTEKADETTQSTTRKPKPTYPSYPIYPTSSVYKTYPVYNSTAAPTNENTTQLPFDKVVKINAVEESTEKIDEETTKANGYETYPVYGSTEASKDTETTKKSLDKVVKINAVEESTEKVDETHTTYPSYATYPSSSVYQTYPDYKSSVTPKNDVTTQAPLEKIVKVNAIEEINEKQDEQTTETATVSESTTSKSQPTYPSYPTYPSTNVYQTYPVYGSTEASKDDETTKKSLDKVVKINAVEKEDETTQKAEPTYSSYPTYSASSVYKTYPTYASTEAPKNDETTKMALDKLVKINKAQISTEKAVNETTTTTEPITTKAPTTYPSYQTYTSSSVYKSYSSSETPDDEEDEESTANPLNKSIKINAVSDPETIQNTTFATTPFPETTKGSFHGVEKGPEIDADSVAKSAKTESAEIPEIVKTESVSKNGTQLNLEVTCKRENKKLKLDTLSSDRSNIYFIFLGC
InterPro domains: - IPR002350: Kazal domain (domain) [89-143]
- IPR036058: Kazal domain superfamily (homologous_superfamily) [93-144]
Interaction partners: - Uncharacterized protein
- Mucin 4B, isoform B
- MIP13722p
- Uncharacterized protein
- HDC17346
- GEO10309p1
- Uncharacterized protein, isoform B
- Mucin related 11Da
- Femcoat
- Mucin 12Ea
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0005488 (binding), GO:0005200 (structural constituent of cytoskeleton), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0017022 (myosin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0016043 (cellular component organization), GO:0009887 (animal organ morphogenesis), GO:0048645 (animal organ formation), GO:0090066 (regulation of anatomical structure size), GO:0048513 (animal organ development), GO:0090596 (sensory organ morphogenesis), GO:0007444 (imaginal disc development), GO:0045229 (external encapsulating structure organization), GO:0043062 (extracellular structure organization), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0030199 (collagen fibril organization), GO:0048592 (eye morphogenesis), GO:0030198 (extracellular matrix organization), GO:0150063 (visual system development), GO:0001745 (compound eye morphogenesis), GO:0048749 (compound eye development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure)
Protein: Glycine hydroxymethyltransferase (Serine methylase) (G3V4W5)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTT
InterPro domains: - IPR015421: Pyridoxal phosphate-dependent transferase, major domain (homologous_superfamily) [78-237]
- IPR039429: Serine hydroxymethyltransferase-like domain (domain) [49-198]
- IPR049943: Serine hydroxymethyltransferase-like (family) [35-198]
- IPR015424: Pyridoxal phosphate-dependent transferase (homologous_superfamily) [45-237]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0005515 (protein binding), GO:0016829 (lyase activity), GO:0042802 (identical protein binding), GO:0016830 (carbon-carbon lyase activity), GO:0016831 (carboxy-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006520 (amino acid metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006082 (organic acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:1901605 (alpha-amino acid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0009069 (serine family amino acid metabolic process), GO:0006544 (glycine metabolic process), GO:0006563 (L-serine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015630 (microtubule cytoskeleton)
Protein: Pteridine reductase (O76290)
Organism: Trypanosoma brucei brucei
Function: Not known
Sequence: MEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQGDHEDNSNGKTVETQVAELIGTNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA
InterPro domains: - IPR014058: Pteridine reductase (family) [3-268]
- IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [5-265]
- IPR020904: Short-chain dehydrogenase/reductase, conserved site (conserved_site) [161-189]
- IPR002347: Short-chain dehydrogenase/reductase SDR (family) [5-264]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016645 (oxidoreductase activity, acting on the CH-NH group of donors), GO:0016646 (oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006066 (alcohol metabolic process), GO:0044107 (cellular alcohol metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0016125 (sterol metabolic process), GO:1902652 (secondary alcohol metabolic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0008204 (ergosterol metabolic process), GO:0008202 (steroid metabolic process), GO:0097384 (cellular lipid biosynthetic process), GO:1901617 (organic hydroxy compound biosynthetic process), GO:0044108 (cellular alcohol biosynthetic process), GO:0046165 (alcohol biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0016128 (phytosteroid metabolic process), GO:0006696 (ergosterol biosynthetic process), GO:0006694 (steroid biosynthetic process), GO:0016126 (sterol biosynthetic process), GO:0016129 (phytosteroid biosynthetic process), GO:1902653 (secondary alcohol biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: HIT family protein (Q72BI4)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Function: Not known
Sequence: MAIRGFAFMETLWAPWRIDYILGPKPDSCVFCLPEHTGEDEARLILYRGRYNFVIMNKFPYNNGHLMVTPYRHVMDLAALAPEEAHECMDLIQSCVRILKGRFNPQGINVGLNLGEAAGAGIREHLHFHLVPRWNGDSSFMAVMNETRVIPEHLSSTYKALKPHFDRLAADGDA
InterPro domains: - IPR039383: FHIT family (family) [29-154]
- IPR011146: HIT-like domain (domain) [30-140]
- IPR052908: AP-4-A phosphorylase (family) [9-167]
- IPR036265: HIT-like superfamily (homologous_superfamily) [3-170]
Interaction partners: - Lipopolysaccharide assembly protein A domain-containing protein
- sulfate adenylyltransferase
- Uncharacterized protein
- Threonine--tRNA ligase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0044248 (cellular catabolic process), GO:0044248 (cellular catabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901575 (organic substance catabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0034655 (nucleobase-containing compound catabolic process), GO:0044270 (cellular nitrogen compound catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:1901136 (carbohydrate derivative catabolic process), GO:0019439 (aromatic compound catabolic process), GO:1901361 (organic cyclic compound catabolic process), GO:0046700 (heterocycle catabolic process), GO:1901657 (glycosyl compound metabolic process), GO:0034656 (nucleobase-containing small molecule catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Cell cycle associated protein Mob1-2 (Q95UM8)
Organism: Trypanosoma brucei
Function: Not known
Sequence: MKRFKAKLFDSDRTYKPKKKHKEGTERYNLHKFAKSLVRSGDLSAAVKLPQGADLNHWLSVHTVDFYNITNVLYGSLTEFCTNSSCPVMSSGPRYEYLWRDPPEYPKATKVSAPEYVRLLMEWIERQINDERVFPSEDRNPYPPDFADRVKACFKRLFRVYAHVYYSHFAKIRELQEESHINTALKHFMYFVWEFDLIPREEVSPLRELLVNLMGQRAKEKLEVP
InterPro domains: - IPR005301: MOB kinase activator family (family) [12-213]
- IPR036703: MOB kinase activator superfamily (homologous_superfamily) [7-217]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051301 (cell division)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: N-succinyl-L-Arg/Lys racemase (EC 5.1.1.-) (N-succinyl amino acid racemase) (NSAR) (Q81IL5)
Organism: Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)
Function: Catalyzes efficient racemization of N-succinyl-L-Arg and N-succinyl-L-Lys, suggesting that these are physiological substrates of this enzyme. Has low activity with L-Asp-L-Lys, and even lower activity with L-Leu-L-Arg, L-Leu-L-Lys, N-succinyl-L-His and N-succinyl-L-Met (in vitro).
Sequence: MKITAIHLYAIRLPLRNPFVISYGSYSDMPSIIVKMETDEGIIGYGEGVADDHVTGESWESTFHTLKHTLTPALIGQNPMNIEKIHDMMDNTIYGVPTAKAAIDIACFDIMGKKLNQPVYQLIGGRYHEEFPVTHVLSIADPENMAEEAASMIQKGYQSFKMKVGTNVKEDVKRIEAVRERVGNDIAIRVDVNQGWKNSANTLTALRSLGHLNIDWIEQPVIADDIDAMAHIRSKTDLPLMIDEGLKSSREMRQIIKLEAADKVNIKLMKCGGIYPAVKLAHQAEMAGIECQVGSMVESSVASSAGFHVAFSKKIITSVELTGPLKFTKDIGNLHYDVPFIRLNEKPGLGIEINEDTLQELTVFQDIVR
InterPro domains: - IPR029065: Enolase C-terminal domain-like (domain) [145-356]
- IPR013341: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain (domain) [12-124]
- IPR013342: Mandelate racemase/muconate lactonizing enzyme, C-terminal (domain) [142-239]
- IPR029017: Enolase-like, N-terminal (homologous_superfamily) [1-356]
- IPR034603: Dipeptide epimerase (family) [5-327]
- IPR036849: Enolase-like, C-terminal domain superfamily (homologous_superfamily) [112-363]
Interaction partners: - Hypothetical protein.
- (S)-2-hydroxy-acid oxidase chain D.
- Cell wall-associated hydrolase.
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016853 (isomerase activity), GO:0043167 (ion binding), GO:0016854 (racemase and epimerase activity), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0000287 (magnesium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0043603 (amide metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006518 (peptide metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Eukaryotic translation initiation factor 4C (Q4V9N9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Sequence: MPKNKGKGGKNRRRGKNENESEKRELVFKEDGQEYAQVIKMLGNGRLEAMCFDGVKRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNADEARSLKAYGELPEHAKINETDTFGPGDDDEIQFDDIGDDDEDIDDI
InterPro domains: - IPR018104: Translation initiation factor 1A (eIF-1A), conserved site (conserved_site) [41-63]
- IPR001253: Translation initiation factor 1A (eIF-1A) (family) [1-142]
- IPR012340: Nucleic acid-binding, OB-fold (homologous_superfamily) [2-144]
- IPR006196: RNA-binding domain, S1, IF1 type (domain) [22-96]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009790 (embryo development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0022008 (neurogenesis), GO:0007399 (nervous system development), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development), GO:0048699 (generation of neurons)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Group 2 truncated hemoglobin GlbO (Hemoglobin-like protein HbO) (Truncated hemoglobin) (trHbO) (P9WN23)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: When expressed in E.coli and M.smegmatis, HbO increases oxygen uptake. Membrane vesicles of E.coli carrying HbO show a respiration activity about twice that of membranes without HbO. HbO seems to interact with a terminal oxidase. Therefore, HbO could participate in oxygen/electron-transfer process, suggesting a function related to the facilitation of oxygen transfer during aerobic metabolism of M.tuberculosis.
Subcellular location: Cell membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.
Sequence: MPKSFYDAVGGAKTFDAIVSRFYAQVAEDEVLRRVYPEDDLAGAEERLRMFLEQYWGGPRTYSEQRGHPRLRMRHAPFRISLIERDAWLRCMHTAVASIDSETLDDEHRRELLDYLEMAAHSLVNSPF
InterPro domains: - IPR012292: Globin/Protoglobin (homologous_superfamily) [1-128]
- IPR044203: Group 2 truncated hemoglobin GlbO/Two-on-two hemoglobin-3-like (family) [4-125]
- IPR019795: Globin, bacterial-like, conserved site (conserved_site) [51-75]
- IPR001486: Truncated hemoglobin (family) [4-121]
- IPR009050: Globin-like superfamily (homologous_superfamily) [4-127]
Interaction partners: - Group 1 truncated hemoglobin GlbN
- Probable alpha-glucosidase AglA
- HNH nuclease domain-containing protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140104 (molecular carrier activity), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0051234 (establishment of localization), GO:0009628 (response to abiotic stimulus), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0001666 (response to hypoxia), GO:0070482 (response to oxygen levels), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0006810 (transport), GO:0015669 (gas transport), GO:0036293 (response to decreased oxygen levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)