Protein: RNA helicase (EC 3.6.4.13) (D3ZUC2)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Cytoplasm, P-body {ECO:0000256|ARBA:ARBA00004201}.
Sequence: MSWALPFALQLFVPRLWRVGVGVALAEAPRSSRLFRGPQAIATFGSWLAARGGSLGFISDPPAWAAAAAAMPSKFSCRKLRETGQGFESFLAERGLDLETDRERLRAIYNRDFKPSYGTPAPGFSSMLYGMKIANLAFVTKTRVRFFKLDRWADVQLPEKRRIKPGSSISKQHRSLLARIFHDRAEYLHGKHGVDVEVQGPHEARDGQLLIRLDLNRKEVLTLRLRNGGTKPVTLTHLFPLCWTPQFVFYHGEQDLPCPLGPGESYELHVYCKTSIVGYFPATVLWELLGPGESGAEGAETFYIARFLAAVAHSPLAAQLKPTTPFKRPPRLTRNPVSTNRIEEGERPDRAKGYELELSLALGTYYPPIRLRQLLPTLLQGPSIFTSPKEVAEIKAQLETTLKSRNYEVKLRLLLHLEELQMEHDIRHYDLESVPMTWDPVDQNPRLLTLEVPGVTESRPSVLRGDHLFALLSSEIQQEDPVTYKGFVHKVELDRVKLSFSPSLLSRFVDGLTFKVNFTFNRQPLRVQHRALELTGRWVLWPTLFPVASRGVSLLPSDVKFKLYDRSLESNPEQLQAMKHIVRGTTRPAPYIIFGPPGTGKTVTLVEAIKQVVKHLPKAHILACTPSNSGADLLCQRLRVHLPSSIYRLLAPSRDIRMVPEDIKTCCNWDPKKGEYVYPAKKHLQQYRVLITTLITASRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLMDVKETGNPGGQLVLAGDPRQLGPVLRSPLAQKHGLGYSLLERLLTYNSLYKKGPNGYDPQFITKLLRNYRSHPTILDIPNQLYYDGELQACADVVDRERFCRWEGLPQQGFPIIFHGVMGKDEREGNSPSFFNPEEAATVTSYLRQLLAPSSKKGKARLSPRSVGVISPYRKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLKNPKRFNVAVTRAKALLIVVGNPLLLGHDPDWKTFLEFCKENGGYTGCPFPAKLDLQQGQDLLQGLSKLSPSTSGPRRHQRLPQEREGEEGLPLQVEPEWRNEL
InterPro domains: - IPR026122: Helicase MOV-10/SDE3, DEXXQ/H-box helicase domain (domain) [569-804]
- IPR041677: DNA2/NAM7 helicase, helicase domain (domain) [570-761]
- IPR047187: Upf1-like, C-terminal helicase domain (domain) [805-1010]
- IPR049075: Helicase MOV-10, N-terminal (domain) [81-146]
- IPR049080: Helicase MOV-10-like, beta-barrel domain (domain) [429-518]
- IPR041679: DNA2/NAM7 helicase-like, C-terminal (domain) [771-992]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [553-1019]
- IPR049077: Helicase MOV-10, Ig-like domain (domain) [184-311]
- IPR049079: Helicase MOV-10, helical domain (domain) [362-428]
Interaction partners: - Protein argonaute-2
- Protein argonaute-1
- Fragile X messenger ribonucleoprotein 1
- Endoribonuclease Dicer
- Trinucleotide repeat containing adaptor 6A
- ATP-dependent RNA helicase
- ATP-dependent RNA helicase A
- Trinucleotide repeat-containing gene 6C protein
- Protein argonaute-3
- ATP-dependent RNA helicase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:1901700 (response to oxygen-containing compound), GO:0043207 (response to external biotic stimulus), GO:0071216 (cellular response to biotic stimulus), GO:0010033 (response to organic substance), GO:0009617 (response to bacterium), GO:0002237 (response to molecule of bacterial origin), GO:0034097 (response to cytokine), GO:0071219 (cellular response to molecule of bacterial origin), GO:0032496 (response to lipopolysaccharide), GO:0033993 (response to lipid), GO:0002237 (response to molecule of bacterial origin), GO:0071222 (cellular response to lipopolysaccharide), GO:0071396 (cellular response to lipid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)