Protein: UDP-glucuronosyltransferase (Q13460)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Sequence: MARTGWTSPIPLCVSLLLTCGFAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVVVMPEVSWQLGKSLNCTVKTYSTSYTLEDLDREFMDFADAQWKAQVRSLFSLFLSSSNGFFNLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDACALIVAKYFSLPSVVFARGIGCHYLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLFCQYFSKNALEIASEILQTPVTAYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMVSHLSFSTLGIILALEIKKRFLTEL
InterPro domains: - IPR002213: UDP-glucuronosyl/UDP-glucosyltransferase (family) [26-285]
- IPR050271: UDP-glycosyltransferase (family) [36-284]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0030234 (enzyme regulator activity), GO:0036094 (small molecule binding), GO:0016740 (transferase activity), GO:0008289 (lipid binding), GO:0097159 (organic cyclic compound binding), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0140678 (molecular function inhibitor activity), GO:0005496 (steroid binding), GO:0005504 (fatty acid binding), GO:0016757 (glycosyltransferase activity), GO:0043177 (organic acid binding), GO:0046983 (protein dimerization activity), GO:0019840 (isoprenoid binding), GO:0043168 (anion binding), GO:0042802 (identical protein binding), GO:0019899 (enzyme binding), GO:0004857 (enzyme inhibitor activity), GO:0016758 (hexosyltransferase activity), GO:0008194 (UDP-glycosyltransferase activity), GO:0005501 (retinoid binding), GO:0042803 (protein homodimerization activity), GO:0031406 (carboxylic acid binding), GO:0046982 (protein heterodimerization activity), GO:0033293 (monocarboxylic acid binding), GO:0001972 (retinoic acid binding), GO:0015020 (glucuronosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0042440 (pigment metabolic process), GO:0042445 (hormone metabolic process), GO:0019748 (secondary metabolic process), GO:0071704 (organic substance metabolic process), GO:0009892 (negative regulation of metabolic process), GO:0065008 (regulation of biological quality), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0065009 (regulation of molecular function), GO:0048523 (negative regulation of cellular process), GO:0044238 (primary metabolic process), GO:0050790 (regulation of catalytic activity), GO:0045833 (negative regulation of lipid metabolic process), GO:0051552 (flavone metabolic process), GO:0009410 (response to xenobiotic stimulus), GO:0046483 (heterocycle metabolic process), GO:0044092 (negative regulation of molecular function), GO:0044255 (cellular lipid metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0006805 (xenobiotic metabolic process), GO:0010817 (regulation of hormone levels), GO:0031324 (negative regulation of cellular metabolic process), GO:0045912 (negative regulation of carbohydrate metabolic process), GO:0009812 (flavonoid metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006629 (lipid metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0006082 (organic acid metabolic process), GO:0009698 (phenylpropanoid metabolic process), GO:0062012 (regulation of small molecule metabolic process), GO:0062014 (negative regulation of small molecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0042573 (retinoic acid metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0043086 (negative regulation of catalytic activity), GO:0010565 (regulation of cellular ketone metabolic process), GO:0071466 (cellular response to xenobiotic stimulus), GO:0006720 (isoprenoid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0008202 (steroid metabolic process), GO:0010675 (regulation of cellular carbohydrate metabolic process), GO:0006109 (regulation of carbohydrate metabolic process), GO:0009804 (coumarin metabolic process), GO:0006631 (fatty acid metabolic process), GO:0045922 (negative regulation of fatty acid metabolic process), GO:0045939 (negative regulation of steroid metabolic process), GO:0010677 (negative regulation of cellular carbohydrate metabolic process), GO:0051338 (regulation of transferase activity), GO:0019216 (regulation of lipid metabolic process), GO:0019218 (regulation of steroid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0051348 (negative regulation of transferase activity), GO:0006721 (terpenoid metabolic process), GO:0019217 (regulation of fatty acid metabolic process), GO:0016101 (diterpenoid metabolic process), GO:0032787 (monocarboxylic acid metabolic process), GO:0001523 (retinoid metabolic process), GO:0006063 (uronic acid metabolic process), GO:0019585 (glucuronate metabolic process), GO:0052695 (cellular glucuronidation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)