Protein: Tight junction protein 3 (A0A8M2BHQ8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
Sequence: MEEMTIWEQHTVTLSKDSKVGFGFAVSGGLDKPNPANGDAAVVVSDVIPTGPAMGRLQTRDQIVMVNGVSMENVTSLYTIQNLRKCGKTANITVKRPRTIQIPASSRPTRSASQSNILDDKGPQYKGQRGPDTTRTRRARSVTPDRNGHDLPITSGYKRLPNQDVQNKPIKTTLIKKKPTDEYGMKLGSQIFIKHMTPTGLAAKEGSLQEGDLVLKINGMTTENLSLLETKHLVEKSRGNLTMLVLRDDRKFLVSIPEVEDSPQNSSDERREDSSSELEEISDLDSDLPVTNRASRRKDRKSNRNRADPVSKKLESPPLRSTLTRPAQSMPPRRVPSESESDRSNSPPPRHDTLDHRNKVLSGYSTLPNPRASPITSSSTSRPRRAVSESDSDRSASPPPRRESPRPDNHSRYKVLPDLPPPGLKPSSLSMSQDFPRRMASPYRPPPRDASESESDESARPQRRQGTPASQESRNRYRAAPEVKAAAVMEPPKWAKPSTPVQRAPSESESDGSYNSPPKQPPSPVSKSSRIKGPEMQMPITSIRQDPPLRAAPARPPPEDSSDSERAQSPLRRSDSHNSDHSFPRANGTLRSNVSIPNHTALTSKAVEEPLYVLPPDAVPTPNLGYSSDQNHISFVKEGSVGLRLVGGNDVGIFVGGVQPNSPAQKQGITEGDQILEVNGMDFNHFTREEAAMYLMNIRGGERIDMRTQNKADIYKKILKSNLGDSFYIRTHYDHVADSSVGLSFTRGEVFRVVDTMHRGKLGTWLAVRMGNDLHELDKGTIPNQTRAETLANLEQAQRISAAERQASGPRAEFWKLRGLRGAKKSNRRTRDDLLQLTIQGKFPAYEKVLLKEANFKRPIVILGPLNDIANEKLARELPDEFEIAEMVPRSGNDSSSSVIKLDTVRRIAEQDKHPLLDITPTAIERLNYIQYHPMVLFLDPHSRKDVKSMRQKYMPGSSKSSRRLYAQALKLRKNYSTLFSARIDLQPNTNMWYDVLKDKIRQQQSKPVWVSEVAMEGGAEEDLDAFNRANNSDYLSGASDYEDTDGEAFTDGEAYTDNEDLEEPLGGIAKHRSSALARSSEPASVLNHSPEPPYNLHEEEEEPEYTLPPSEVPPILHVPEPRSPRLVAGIPEEQEDVPSQRSFTDSDFSNDDVVAPQTPSDAPPKFRAPDPKDVQSKTPPLSAIEERLQQARMAEQIEPERKPSPSFIVLAHHEAMQMRRTQIRGSDSDSDENDRDEDEYDEAEDIEWGPATEL
InterPro domains: - IPR036028: SH3-like domain superfamily (homologous_superfamily) [727-798]
- IPR001478: PDZ domain (domain) [11-712]
- IPR001452: SH3 domain (domain) [728-789]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [859-1012]
- IPR008145: Guanylate kinase/L-type calcium channel beta subunit (domain) [818-1005]
- IPR008144: Guanylate kinase-like domain (domain) [815-1002]
- IPR036034: PDZ superfamily (homologous_superfamily) [1-726]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009790 (embryo development), GO:0048729 (tissue morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0009888 (tissue development), GO:0007369 (gastrulation), GO:0002009 (morphogenesis of an epithelium), GO:0055113 (epiboly involved in gastrulation with mouth forming second), GO:0060429 (epithelium development), GO:0002011 (morphogenesis of an epithelial sheet), GO:0001702 (gastrulation with mouth forming second), GO:0090504 (epiboly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030054 (cell junction), GO:0043229 (intracellular organelle), GO:0070161 (anchoring junction), GO:0043227 (membrane-bounded organelle), GO:0005911 (cell-cell junction), GO:0043231 (intracellular membrane-bounded organelle), GO:0043296 (apical junction complex), GO:0070160 (tight junction), GO:0005634 (nucleus), GO:0005923 (bicellular tight junction)