Protein: Vacuolar protein sorting-associated protein 51 homolog (F1M4I4)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Golgi apparatus, trans-Golgi network {ECO:0000256|RuleBase:RU368010}. Recycling endosome {ECO:0000256|RuleBase:RU368010}. Note=Localizes to the trans-Golgi network as part of the GARP complex, while it localizes to recycling endosomes as part of the EARP complex. {ECO:0000256|RuleBase:RU368010}.
Sequence: MAAAAAVGPGLGSGPGDSPEGSEADAPERRRKAHGMLKLYYGLSEGEATGHSAGSDPLDPTDLNGAHFDPEVYLDKLRRECPLAQLMDSETDMVRQIRALDSDMQTLVYENYNKFISATDTIRKMKNDFRKMEDEMDRLATNMAVITNFSARISATLQDRHERITKLAGVHALLRKLQFLFELPSRLTKCVELGAYGQAVRYQGRARAVLQQYQHLPSFRAIQDDCQVITARLAQQLRQRFREGCSGAPEQAECVELLLALGEPAEELCEEFLAHARGRLEEELSSLETELGPSPPAPDVLEFTDRGGNGFVGGLCQVAAAYQELFAAQGPAGAEKLAAFAQELGGRYFALVERRLAQEQGGSDNSLLVRALDRFHRRLRAPGALLAAAGLSESATEIVERVARERLSHHLQGLKAAFLSCLTDVRQALAAPRLAGKEGPSLAELLANVASSILSHIKASLASVHLFTAKEVSFSNKPYFRGEFCSQGVREGLIVGFIRSMCQTAQGFCDSPGEKGGATPPALLLLLSRLCLDYETATISYILTLTDEQFLVQDQSPVTPVSTLCAEARETARRLLTHYVKVQGLVISQMLRKSVETRDWLSTLEPRNVRAVMKRVVEDTTAIDVQVGLLYEEGVRKAQSSDSSKRTFSVYSSSRQQGRYAPSYTPSAPMDTNLLSNIQKLFSERIDVFSPVEFNKVSVLTGIIKISLKTLLECVRLRTFGRFGLQQVQVDCHFLQLYLWRFVADEELVHLLLDEVVASAALRCPDPVPMEPSVVEVICERG
InterPro domains: - IPR014812: Vacuolar protein sorting-associated protein 51 (family) [24-781]
- IPR016159: Cullin repeat-like-containing domain superfamily (homologous_superfamily) [174-371]
Interaction partners: - Vacuolar protein sorting-associated protein 52 homolog
- Vacuolar protein sorting-associated protein 53 homolog
- Vacuolar protein sorting-associated protein 54
- Syndetin
- Syntaxin-6
- EARP and GARP complex-interacting protein 1
- Syntaxin-16
- Conserved oligomeric Golgi complex subunit 1
- Conserved oligomeric Golgi complex subunit 5
- Conserved oligomeric Golgi complex subunit 8
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0009987 (cellular process), GO:0051641 (cellular localization), GO:0051234 (establishment of localization), GO:0033036 (macromolecule localization), GO:0010876 (lipid localization), GO:0046907 (intracellular transport), GO:0006810 (transport), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0045184 (establishment of protein localization), GO:0006869 (lipid transport), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0015031 (protein transport), GO:0032365 (intracellular lipid transport), GO:0016482 (cytosolic transport), GO:0071702 (organic substance transport), GO:0016192 (vesicle-mediated transport), GO:0008104 (protein localization), GO:0015850 (organic hydroxy compound transport), GO:0006605 (protein targeting), GO:0032366 (intracellular sterol transport), GO:0015918 (sterol transport), GO:0032367 (intracellular cholesterol transport), GO:0030301 (cholesterol transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0031984 (organelle subcompartment), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0098791 (Golgi apparatus subcompartment), GO:0043228 (non-membrane-bounded organelle), GO:0005794 (Golgi apparatus), GO:0043227 (membrane-bounded organelle), GO:0031985 (Golgi cisterna), GO:0043231 (intracellular membrane-bounded organelle), GO:0005795 (Golgi stack), GO:0098588 (bounding membrane of organelle), GO:0032588 (trans-Golgi network membrane), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005802 (trans-Golgi network), GO:0031982 (vesicle), GO:0000139 (Golgi membrane), GO:0005730 (nucleolus), GO:0097708 (intracellular vesicle), GO:0005634 (nucleus), GO:0000138 (Golgi trans cisterna)