Protein: Histone transcription regulator 3 homolog (Q5ADX2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Has a role in a nucleosome assembly pathway that is required for the integrity of heterochromatin and proper chromosome segregation
Subcellular location: Nucleus
Sequence: MSSFIPLNFLEDTVSKKDLEEEHTRELQVEQAYKLFQSALKLQKQKQYESAYKVYEELFKLDIVSNHYFEELDFIRGLQDGSQNTDTDELTLLSPNVKSLRYLIFRNRGFLYLDMLKSNTENKSAEKVKEMFYPLLDDFCIALLYNEPDEKLLETLHEIFSYIGSERLSRFVLEYSLTSRKESDDLSGLLPIDQTVLSQYKTMLEHLSSGKFPKLDLKHLSFLEPIRLDIFAQQEKLASKKVAVIKSTSTKWVDLLDAINIHLKENQDESKIEDANRPRIRIFEPYVLTEEPLDIVRIEFTKRGVAVPATETEVTKAQPEQIVQERKPEEDNRVQRSSKRLSKVEDEIPAVTLESSHFLNMDYFRNQMNETIPNFEIFDVCSTYVEDGSGAQYIKDFKNIVSDWNDSYARAILSYDTAKSEDDNLKLLDLLSGYGKSEELKEKNIPPLGEIDIEFPELNYVEFKTYIIKHLLSKILTTKWSDKLYEKFTEWIVQFEGYIINDIDVESAIGVLEVLVDISTSLESQIKDSINNKLNKAVVNSMCQDLLRIKDKIIRWINYIETFPINDLQVASRFKWCQIIKEKAETKSWTENHPVKHKLQKLLGDAHFKINYPNYKNFIDFSKDSINSQLTIISVLAIFWRILSTSSTEDNKEAIRLLEDILLDSNTEPSDAILSIRNFLKQGSIDMKLSLWNILLSFYQSSNSGDKLTVGFEECVLFLNDYLVNEYVLLDEESRLVTLSRILGFYGSSISFVVTSLASTNWILMHPIKVQTLRLFFELSLLFEINEEASYISSLATSIKSKSTKSYHHLTNTLIKTIILILASIQKSNPQILHSVIRLFHTQLGLIGICGHAGGSFLEIAQEYLKSLPNSDQDICQIIKCKYHYSISIDGVVPADHGTARLDELNKNDCKELASFVLPLCFSKGGSTLNNVPKHDIKLLIDEIYDVIGDPDFDSNEALGRNKATLNYFLDNTRLTKRLFQEAFHGLVRLELGEAEEDKQFNGLYYIEGLLLFSSYKLRKKNMQSRAVELESAISLFENDIICGSNRFESWFLLGQSYGYLVEDDLIWTADKLTASDRKITTANLQRKSLICYLMAINKSLDESIKDVIKPVVGNLMSLFAKEMFSAVCEPMSMHAFKVQSHPRFINRVNGALFEPVSQFPAVDKTVCLKIIQQSLQLSIKSSCREWSDYYYLAKVQRKLDKPAGLVMETMASACRSAFKNKHADNIIEPHYNLVSFALKYVKSNRLDSKDALKYLIEDPLIKLEVGEETDFIKLIIKALNKIDSSDKKNWQHKAKYRLARLMQEEYHDVKGAIDQMSSFISLKTPNKALVSIWKPEPERPGKHFLYTFQYIHFYIELLKEIDDLDSLVAMLPKLRRSNSVMINLSIAWEILCSSVCKIIRESYGIGDNFEFTENLINTLPYQTFAANVKLLPDMMRRQSVPENLKSVLCFLFTVNDIKKLNNGYGPTSFIDDTLVTLYFMIYLNYFEKSSTEVTTDSPGLKKKIAKRDIFPLTNDILKAFKKDIEDVTKQKSYNELITAQKLKQGLNEDKSLENVPASANVNEIIVIDDDDDDNLSQEPATKKSKTESNS
InterPro domains: - IPR033053: Histone transcription regulator 3/CABIN1 (family) [1-1520]
Interaction partners: - Protein HIR2
- Protein HIR1
- Histone chaperone ASF1
- Cac2p
- Histone H2A.Z-specific chaperone CHZ1
- Hpc2p
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0019538 (protein metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:0009059 (macromolecule biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0043412 (macromolecule modification), GO:0090304 (nucleic acid metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0018130 (heterocycle biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0010467 (gene expression), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0016070 (RNA metabolic process), GO:0032774 (RNA biosynthetic process), GO:0097659 (nucleic acid-templated transcription), GO:0043543 (protein acylation), GO:0018193 (peptidyl-amino acid modification), GO:0016570 (histone modification), GO:0006473 (protein acetylation), GO:0018205 (peptidyl-lysine modification), GO:0006351 (DNA-templated transcription), GO:0006353 (DNA-templated transcription termination), GO:0018394 (peptidyl-lysine acetylation), GO:0006475 (internal protein amino acid acetylation), GO:0006366 (transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)