Protein: Breast cancer anti-estrogen resistance protein 1 (A0A2R8Q9D0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell junction, focal adhesion. Cell projection, axon. Cytoplasm
Sequence: MSVPIGSRPLNPSSAGSAALLDHHLLHSDPLNVLAKALYDNVAESPDELSFRKGDIMTVLERDTQGLEGWWLCSLHGRQGIVPGNRLKILVGMYDKQQQQQLQQLANQPSPTQSLINLPQSAYNKIPPAAQYTAMHPAFTPSGSANSTNPDGVYMLPPSHGSSLYQVPSGPPTPQPQPKAPALAKKQTHVQYPPTTQDVYQVPPSINAPGQDIYQVPPAAGGQCPGQDVYQVPPSVNQTQDVYQIPPSLDRSWDSPKPMGKVVVPTRVGQVYVYDTGKNEQDEYDVPRHLPPSQDIYDVPPTRTQYIQQVYDTPPMAMKGPPSGQEIYDTPPSVDKSQLHYQQTVYDIPPSVSKDVPDGPIREETYDVPPHFAKMKSLENQNQAYLSQIPGGPEPPIPEDVYDVPPPQLIGKRQPEGQEIYDIPASLRKGGPQDHHPTDVYDFPRERPAGEDSGDYVYDVPPQVVRDAAATEELTVSFKRLSASSTGSTRSNLSTSSLDMVPVRESSGPGRLLLLDLDQAMERLSRHQQAVESSVSLLMSFISGNWRSSTQMESNLPAIRQAVDRIRVAVRDLLEFARGAVANATQATDRTLQTKLGKQVQKMEEAFQGLVRYSQALDTLGWSPAALMTSQPGTGGDDLDRLIMCARGVPDDTKQLASFLHGNASLLFKRTNKQQQLPLPPVPHTGDSLTNNNNISAYQSGTPERANIQSRPLPSPPKFSAEEEAPDRPYETTEEGWMEDYDYVHLQGKEEFEKNQRQLLEKGSIKQNKTQLEQQQLKQFERLEQEVSRPINNDISGWTPPSHYPQTQRSKLCMGDRQLLLFYMEQCEANITTLTNAIDAFYSSINNNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQAKSPEVRTRVAQHSNTLCDKLKDIVVSTKTAALQYPSPGSTRDMTERVRELAGCTQQFRMALNQLLAM
InterPro domains: - IPR036028: SH3-like domain superfamily (homologous_superfamily) [30-118]
- IPR001452: SH3 domain (domain) [30-92]
- IPR037362: CAS family (family) [32-945]
- IPR014928: Serine rich protein interaction domain (domain) [515-671]
- IPR038319: CAS, serine rich four helix bundle domain superfamily (homologous_superfamily) [503-673]
- IPR035745: BCAR1, SH3 domain (domain) [31-97]
- IPR021901: CAS family, C-terminal (domain) [732-940]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0071840 (cellular component organization or biogenesis), GO:0030029 (actin filament-based process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0032989 (cellular component morphogenesis), GO:0061061 (muscle structure development), GO:0044085 (cellular component biogenesis), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0016043 (cellular component organization), GO:0030036 (actin cytoskeleton organization), GO:0010927 (cellular component assembly involved in morphogenesis), GO:0016477 (cell migration), GO:0022008 (neurogenesis), GO:0048882 (lateral line development), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0042692 (muscle cell differentiation), GO:0048880 (sensory system development), GO:0055001 (muscle cell development), GO:0072359 (circulatory system development), GO:0060537 (muscle tissue development), GO:0007423 (sensory organ development), GO:0007517 (muscle organ development), GO:0006996 (organelle organization), GO:0030239 (myofibril assembly), GO:0031032 (actomyosin structure organization), GO:0030182 (neuron differentiation), GO:0097435 (supramolecular fiber organization), GO:0048666 (neuron development), GO:0007507 (heart development), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0007010 (cytoskeleton organization), GO:0048925 (lateral line system development), GO:0055007 (cardiac muscle cell differentiation), GO:0051146 (striated muscle cell differentiation), GO:0014706 (striated muscle tissue development), GO:0048738 (cardiac muscle tissue development), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0060538 (skeletal muscle organ development), GO:0120036 (plasma membrane bounded cell projection organization), GO:0048884 (neuromast development), GO:0048916 (posterior lateral line development), GO:0055002 (striated muscle cell development), GO:0150063 (visual system development), GO:0140694 (non-membrane-bounded organelle assembly), GO:0061564 (axon development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0005886 (plasma membrane), GO:0030055 (cell-substrate junction), GO:0005925 (focal adhesion)