wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: XO lethal protein 1 (Q23229)
Organism: Caenorhabditis elegans
Function: Sex-determining factor that is required for sexual differentiation and X chromosome dosage compensation to promote male development. High expression during gastrulation triggers male development, while low expression at that time triggers hermaphrodite development. Although related to GHMP kinase, its mode of action remains unclear.
Subcellular location: Nucleus {ECO:0000269|PubMed:7813020}.
Sequence: MQVEANSERRVKILGIDRSENSPVLTYMETEDDPNFRNSKLAAAPHTVHMMDSGFLAINRQCLVKGKAILAREPKSSNEHMIDDLPKHAHDQHTLSILRDFIDQLKLHNVYEINFYDPLDSSGKLAVIPMLIALWKCMLASETDICDQEVLKSIMNSVIAKFELQIPCKNAVIDATLSGSREEVHIIAEDGSLENSNGTTEHFNKKHDLVFVKTDLHPEDFTPQMFPSQAKAKLLRDAFNNEEDEDTFPDILVPAYMTAHSKNRVRQEDYTCLEVEFDSQVALEKLMNEHEQVEGFEVQQGGILVALKKDSFFDDELIEKIAIAIATESRQSVSSVSFDLLKLGPGASLVTLANSRRFEPECRVVLQIEVKPVSPGETSSEGISDEHHYEEYDEDDIMEEEEAPSARQDDTYDEDEE
InterPro domains: - IPR015192: Switch protein XOL-1, N-terminal (domain) [18-177]
- IPR014721: Small ribosomal subunit protein uS5 domain 2-type fold, subgroup (homologous_superfamily) [42-188]
- IPR015193: Switch protein XOL-1, GHMP-like (domain) [184-372]
- IPR020568: Ribosomal protein uS5 domain 2-type superfamily (homologous_superfamily) [8-181]
- IPR036554: GHMP kinase, C-terminal domain superfamily (homologous_superfamily) [182-373]
Interaction partners: - Steroid hormone receptor family member cnr14
- Sex determination protein fox-1
- Protein her-1
- T-box transcription factor 18
- Homeobox protein ceh-39
- Sex determination and dosage compensation protein sdc-2
- Sex-determining transformer protein 2
- RNA-binding protein ASD-1
- Lysine-specific demethylase 9
- Chromosome condensation protein dpy-27
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048583 (regulation of response to stimulus), GO:0080134 (regulation of response to stress), GO:0047484 (regulation of response to osmotic stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0042995 (cell projection), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0120025 (plasma membrane bounded cell projection), GO:0043005 (neuron projection), GO:0043231 (intracellular membrane-bounded organelle), GO:0030424 (axon)
Protein: Tat pathway signal protein (O25542)
Organism: Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Function: Not known
Sequence: MKRRDFIKTTTLGATGAVLGAQILQAEESKGSVAKYKIEAQYSIDFDSAEHTSLFIPMPSVVASNVHLQGNHASYKSMLNFGVPYLQVDFLKSTQKKQVHLSYEIASYQLNERLFETSDFVAMGRYERDDASVANIANQLKGTTPKESVRNFYAFIKHEMPKRQKALEGKENLPKRESLPWFATISKESMFVSLCHACGIKSAEVQGLKLGQNSVVKNAPRVEVYLKDSFLAFDFQNNHKEVFIPLNRHKDMQLDSALLATFGDAFALVDGRDLGNYESKLFEKRVSYTIV
InterPro domains: - IPR019546: Twin-arginine translocation pathway, signal sequence, bacterial/archaeal (conserved_site) [3-21]
Interaction partners: - Catalase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0005975 (carbohydrate metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0044262 (cellular carbohydrate metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:1903509 (liposaccharide metabolic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0008653 (lipopolysaccharide metabolic process), GO:0044264 (cellular polysaccharide metabolic process), GO:0016051 (carbohydrate biosynthetic process), GO:0005976 (polysaccharide metabolic process), GO:0034637 (cellular carbohydrate biosynthetic process), GO:0000271 (polysaccharide biosynthetic process), GO:0009103 (lipopolysaccharide biosynthetic process), GO:0033692 (cellular polysaccharide biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0042597 (periplasmic space)
Protein: HIG1 domain family member 2A (Q9CQJ1)
Organism: Mus musculus (Mouse)
Function: Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May be involved in cytochrome c oxidase activity. May play a role in the assembly of respiratory supercomplexes (By similarity).
Subcellular location: Mitochondrion membrane {ECO:0000255|PROSITE-ProRule:PRU00836}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00836}. Mitochondrion inner membrane {ECO:0000250}.
Sequence: MAAPGPVSPEAPFDPSKPPVIEGFSPTVYSNPEGFKEKFIRKTRENPMVPIGCLGTAAALTYGLYCFHRGQSHRSQLMMRTRIAAQGFTVVAILLGLAASAMKSQA
InterPro domains: - IPR050355: Mitochondrial Respiratory Supercomplex Factor 1 (family) [14-105]
- IPR007667: Hypoxia induced protein, domain (domain) [20-106]
Interaction partners: - Cytochrome c oxidase assembly protein COX14
- Cytochrome c oxidase subunit 6A1, mitochondrial
- Ragulator complex protein LAMTOR2
- Cytochrome c oxidase subunit 6B1
- Cytochrome c oxidase subunit 2
- Cytochrome c oxidase subunit 5A, mitochondrial
- Cytochrome c oxidase subunit 3
- Cytochrome c oxidase assembly factor 3 homolog, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 8
- Cytochrome c oxidase subunit 5B, mitochondrial
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0065007 (biological regulation), GO:0048523 (negative regulation of cellular process), GO:0050794 (regulation of cellular process), GO:0060548 (negative regulation of cell death), GO:0010941 (regulation of cell death), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:0043066 (negative regulation of apoptotic process), GO:0042981 (regulation of apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005740 (mitochondrial envelope), GO:0019866 (organelle inner membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031966 (mitochondrial membrane), GO:0005743 (mitochondrial inner membrane), GO:0005634 (nucleus)
Protein: Neuralized E3 ubiquitin protein ligase 1 (A0A096MJM7)
Organism: Rattus norvegicus (Rat)
Function: Not known
Sequence: MGGQITRNTLHDSIGSSFPVPSHRCHHKQKHCPPALSGGGLPATPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFYRINESAAMLFFSGVRTADPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPSLRCEADEARLSVSLCDLNVPGADGEDGAPPAGCPIPQNSLNSQHSRALPAQLDGDLRFHALRAGAHVRILDEQTVARLEHGRDERALVFTSRPVRVAETIFIKVTRSGGARPGALSFGVTTCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHSGDILGLVVNADGELHLSHNGAPAGMQLCVDASQPLWMLFSLHGAITQVRILGSTIMAERGGPSLPCSPASTPTSPSALGSRLSDPLLSTCGSGPLGGSAGGTAPNSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGHMCLCYSCGLRLKKALHACCPICRRPIKDIIKTYRSS
InterPro domains: - IPR006573: Neuralized homology repeat (NHR) domain (domain) [43-431]
- IPR037962: Neuralized (family) [42-556]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [498-556]
- IPR043136: B30.2/SPRY domain superfamily (homologous_superfamily) [48-430]
- IPR001841: Zinc finger, RING-type (domain) [504-544]
Interaction partners: - E3 ubiquitin-protein ligase MIB2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity), GO:0061659 (ubiquitin-like protein ligase activity), GO:0061630 (ubiquitin protein ligase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0061061 (muscle structure development), GO:0009888 (tissue development), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development), GO:0007517 (muscle organ development), GO:0060537 (muscle tissue development), GO:0007519 (skeletal muscle tissue development), GO:0060538 (skeletal muscle organ development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043204 (perikaryon), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0098794 (postsynapse), GO:0044297 (cell body), GO:0036477 (somatodendritic compartment), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0043025 (neuronal cell body), GO:0043197 (dendritic spine), GO:0120025 (plasma membrane bounded cell projection), GO:0097447 (dendritic tree), GO:0045202 (synapse), GO:0005886 (plasma membrane), GO:0099572 (postsynaptic specialization), GO:0043005 (neuron projection), GO:0098984 (neuron to neuron synapse), GO:0014069 (postsynaptic density), GO:0030425 (dendrite), GO:0097440 (apical dendrite), GO:0032279 (asymmetric synapse), GO:0044309 (neuron spine)
Protein: PANX2 protein (Q495U3)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MNLIILVNLIHLFIFRKSNFIFDKLHKVGIKTRRQWRRSQFCDINILAMFCNENRDHIKSLNRLDFITNESDLMYDNVVRQLLAALAQSNHDATPTVRDSGVQTVDPSANPAEPDGAAEPPVVKRPRKKMKWIPTSNPLPQPFKEPLAIMRVENSKAEKPKPARRKTATDTLIAPLLDRSAPDKKHARHFSLDVHPYILGTKKAKAEAVPAALPASRSQEGGFLSQAEDCGLGLAPAPIKDAPLPEKEIPYPTEPARAGLPSGGPFHVRSPPAAPAVAPLTPASLGKAEPLTILSRNATHPLLHINTLYEAREEEDGGPRLPQDVGDLIAIPAPQQILIATFDEPRTVVSTVEF
InterPro domains: - IPR039099: Pannexin (family) [1-172]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0044089 (positive regulation of cellular component biogenesis), GO:0051130 (positive regulation of cellular component organization), GO:0044087 (regulation of cellular component biogenesis), GO:0043254 (regulation of protein-containing complex assembly), GO:0031334 (positive regulation of protein-containing complex assembly), GO:1900225 (regulation of NLRP3 inflammasome complex assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: DUF4911 domain-containing protein (Q72FB7)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Function: Not known
Sequence: MTCVTVAGMAQRMSQSVRKSRPRRPRRPGPPLPPPRLSACLYVRIAPCDVAMFRFLLEAHDNLALFTVLDRHEALLKVVHSPHQERAVRRALTDMCETVPFTVIDFPRPVAAPAS
InterPro domains: - IPR032587: Protein of unknown function DUF4911 (family) [43-99]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0060341 (regulation of cellular localization), GO:0032880 (regulation of protein localization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Type II secretion system protein L (T2SS protein L) (E0SLF6)
Organism: Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
Function: Not known
Subcellular location: Cell inner membrane {ECO:0000256|ARBA:ARBA00004377}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004377}.
Sequence: MNRAENASGKQQLILRLSTETSDSLEWLIWSVSRHQTLTQGSGTLERLQTVLADYPVMSVRVLVPSTDVTFHSLSLPRQSRRQLLQAIPFMLEEQVASDIDQLHFAVMEMQGDNATVAVVQKSRLRSWLNQCETLGVPVETMVPDVMALPRTDSAWSAISHQNLWLFRLDSGIGMAAEDSWYQSLLAGFQPLPAVHCYSPVPASALTWQPQPVTDLLTLAAQASLPISMDLRQGEYAPVKPWKQAVLPWRNVLIALFAWLLLVLGESVWTHYQLYRQADYWRQESVRMYRKLFPDEKQVVNPRAQMQRHLQEARSGMSGFALTEQMNRLQQLVAQNDGVSLQSLSYDRSRDELRLSLRATSYAQMEQFRQQAQAYFQIPPGEMKQEKDHVEGQLILRSQP
InterPro domains: - IPR024230: GspL, cytoplasmic actin-ATPase-like domain (domain) [13-238]
- IPR043129: ATPase, nucleotide binding domain (homologous_superfamily) [12-236]
- IPR025691: GspL periplasmic domain (domain) [246-399]
- IPR007812: Type II secretion system protein GspL (family) [10-397]
Interaction partners: - Type II secretion system protein M
- Type II secretion system protein J
- Type II secretion system protein H
- Type II secretion system protein E
- Type II secretion system core protein G
- Type II secretion system protein C
- Type II secretion system protein K
- Secretin OutD
- Type II secretion system protein I
- Type II secretion system protein F
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0016887 (ATP hydrolysis activity), GO:0016787 (hydrolase activity), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity), GO:0017111 (ribonucleoside triphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0006508 (proteolysis), GO:0051604 (protein maturation), GO:0010467 (gene expression), GO:0016485 (protein processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Kruppel-like transcription factor (Q9WTQ3)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MVDHLLPVDETFSSPKCPVGYLGDRLASRQPYHMLPSPISEDDSDVSSPCSCASPDSQAFCSCYSAGPGPEAQGSILDFLLSRATLGSGGASGGVGDGSGPVTWGSWRRASVPVKEEHLCFPEFLSGDPDDVSRPFQPTLEEIEEFLEENMEAEVKEAPESSSRDLEACSQLSAGSHRSHLHPESGGRECRIPPPGGTSGGGTQGAGEGSAHDGPMPVLLQIQPVAVKQEAGAGPASPGQAPESVKVAQLLVNIQGQTFALLPQVVPSSNLNLSSKFVRIAPVPIAAKPIGSGSLGPGPAGLLVGQKFPKNPAAELLKMHKCTFPGCSKMYTKSSHLKAHLRRHTGEKPFACTWPGCGWRFSRSDELSRHRRSHSGVKPYQCPVCEKKFARSDHLSKHIKVHRFPRSSRAVRAIN
InterPro domains: - IPR013087: Zinc finger C2H2-type (domain) [320-407]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [334-403]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0071495 (cellular response to endogenous stimulus), GO:1901700 (response to oxygen-containing compound), GO:1901698 (response to nitrogen compound), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0071417 (cellular response to organonitrogen compound), GO:1901652 (response to peptide), GO:1901699 (cellular response to nitrogen compound), GO:0010243 (response to organonitrogen compound), GO:1901701 (cellular response to oxygen-containing compound), GO:0071310 (cellular response to organic substance), GO:1901653 (cellular response to peptide)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Superoxide dismutase [Cu-Zn] (EC 1.15.1.1) (E1JH26)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MSSIKIEFAVQMRRGDESYAGALRSALDGVGQVEIDTQEGRVIIQTQRPWSEIQDKIEATGVRAVLSGFGGQSAVALINTTGSVVDKTPIQGVVRFTTITADKKPGVVVDGVVDGLSPGLHGLHIHESGDTSAGCSSVGEHYNPRQSPHGSPAAGAEERHAGDLGNIRADENGRATFRFVDPVLEVWDIIGRAVVLTANADDLGRGGNDQSLIDGNSGERIACGIIARSAGILENFKRICACDGVTLWDERNKPLAGKERSQKL
InterPro domains: - IPR001424: Superoxide dismutase, copper/zinc binding domain (domain) [72-227]
- IPR036423: Superoxide dismutase-like, copper/zinc binding domain superfamily (homologous_superfamily) [74-254]
- IPR024134: Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone (family) [45-253]
- IPR018152: Superoxide dismutase, copper/zinc, binding site (binding_site) [215-226]
Interaction partners: - P-type Cu
- Extracellular superoxide dismutase
- Copper transport protein ATOX1
- superoxide dismutase
- Superoxide dismutase
- Gemini, isoform C
- Copper transport protein
- Protein Malvolio
- Copper transport protein
- Cytochrome c oxidase assembly protein COX11
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140104 (molecular carrier activity), GO:0016530 (metallochaperone activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0065007 (biological regulation), GO:0032501 (multicellular organismal process), GO:0065008 (regulation of biological quality), GO:0008340 (determination of adult lifespan), GO:0006950 (response to stress), GO:0006979 (response to oxidative stress), GO:0031647 (regulation of protein stability), GO:0050821 (protein stabilization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0042579 (microbody), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005777 (peroxisome)
Protein: Rifin (Q8I2E6)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Not known
Sequence: MKLNYTKILLFFFPLNILLTSPSNSHNNNNEPQTTPHHTQTNRSLYESDTESSIYDKDEDMESVKENFERQTSQRFEEYQERMKEKQQKRKEQRDKNIQKIIHKDKMEKNLAEKIEKGCLMCGCGLGSVAGSVGLFGGIAINIWKPTALDAAIEAAIAKSAAKITAVAEAARILAGKEAVIAGLEKLGVSILDNQLLVSYFTTTPYNTASVITTALYKQHYKICVYDPSRNLLSSFGDVNRHIGICNSVWKQISVVSQRGQYISHEEVIKRTVETMVSYAEVSAKAAAKTAEVAEKATIKVAQEKVMEATIYNWYTTIGYTILAILIIVLIMIIIYLILRYRRKKKMKKKAQYTKLLNE
InterPro domains: - IPR006373: Variant surface antigen Rifin (family) [1-359]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response), GO:0042783 (evasion of host immune response), GO:0020033 (antigenic variation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0033643 (host cell part), GO:0043657 (host cell), GO:0033644 (host cell membrane), GO:0020002 (host cell plasma membrane)