Protein: Polyketide synthase PltC (Q4KCY8)
Organism: Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Function: Not known
Sequence: MDNDVRDVSKEQLQESLAQAITTIRALKEKVAGKSSAPVEPIAVVGLGCRLPGSADTPKRLWSLLKHATDAVGDMPSDRLYGTDYYHPDPQAPGKAYVMRGGFIEGVDQFDPGFFGISPKEAEGMDPQQRLALEVAWEALENAAIAPDSLHGKKLGVFMGVSTNDYVRLRQQLGAVEDVNAYQFYGETSFVAGRIAYTLGSRGPAVVLDTSCSSSLVALHQACNSLRSRESELALAGGVNLILSPYGFILVSKLRAVAPDGRCKTFDAAADGYGRAEGCVILALKRLSDAVRDQDPVLAVIEGSAVNNDGASSGITVPNIHAQEEVIRLALGQAGLQGSEVDYVEAHGTGTALGDPIELHALHAVLGKQRPVDAPLLVGSIKANMGHLEPVAGVTGLAKVLLCLQQEALVPQVHFNTPNPRIEWDRLALKVVTESTPWPRQGKARHAGVSSFGVTGTNAHVLVGDAPLRERAQGRDNPWQLITLSAKGETPRRQIAGRYERFIADNSQLELKDLCYTANVGRAHFGHRFAAVADSREGLREQLAAYASRKVVGHVFEGRCQGAAAPLVMLFPGQGCQYRAMAQALYDSEPFFKAQIDECRALLQPLMDVDLLTLVLDAGAASDSYLQQTRYAQPAIFAVEYALARLWMHWGVAADALFGHSFGEISAICVAGAVSLADALRMVEARGRLAQQLMTAGGAMYALGMSEAQLLELLKDRPGSAIELAAVNSPQDVVVAGPQAEVQALAEAALASGCKVKKLAVSHAFHTAATEPMLEAFRQTVAQITFSEPRLPVISSVTGRVHTLSSLSSPDYWCTHTRQAVRFCEGVNTLIAELGVKTFLEVASDAVLTPLIGRHPLADGSLVLASLRRAGDPSRDLRLAAAQLYVGGHNLDWARLHEHDGALRQALPGYAFQRQRYWFDNASGSPLQQVAAGAVGRLLGHSVNAPTPAFESTLDSALLQVVGGEIRDDLALLRPDRLLAALSDELAGHLQLDTYGVSLASITPALAFHVDDQLHLFTELKPLSGAAWEVNCSALSAAAKVAGADWQPVLSLTLEGLPAAVRGGLPDPGHAATQDAGFVYHMQLPAEPDPHGNHLGQVLEYLGQAVPGDAPGSISGIRRWVASRSASPRAQSLVIATSQAHPQQFDCALYDAHGQCVGSLEGLTLAAAPSEEALRGMLYQPDVLYSLDWLERPRQRAEVPQQDRLFTLVSRSPETAAPLVEHLQRGGHRARVLCPQQLLDSARRVLAQDPSQALTDEGEALAADIIVLDGKDIEDAGSTTLQSLSSLQATLFHPLLEMVQALIELGPRGGRLWLVTQGANPVGLDRDQPLQVATGPLWGLGKTLALEHPEHWRGLIDLAPDDPHWARALAEEVSDSDGDDKICLRPGKRYVQRLNHFSAAQLPAQAYAPCPQGSYLITGGMGGIGLAMAQWLLDKGAGAVLITGRRPLEDVATGLERFGAAASRVSYVQADITSPQDMQRLFCGLEASGASLKGIFHAAGISIPQDLKDVDRDSFDQVMRPKVEGTWLLHELSLGLDLDFFVLCSSIASVWGSQHVASYAAANQFLDSLAWQRRAMGLSALVIDWGLWAGGSHLFDEQVLNFLTSVGLKQIAPVQNVGLLSRILASELPQMVVSGVDWNRFKPLLESRGPQPLLQYIRSQAPTARAGDSSNVEILQQLAGADEAAALALLDDYVWEQYAQLLGVKTEQVRAKLEDGGSLMDYGLDSLLVMDMVARCRRDLKLEIKAREFLECPGLMWPDFLARSIKEQGCVAEA
InterPro domains: - IPR020841: Polyketide synthase, beta-ketoacyl synthase domain (domain) [39-468]
- IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [1181-1633]
- IPR016035: Acyl transferase/acyl hydrolase/lysophospholipase (homologous_superfamily) [567-864]
- IPR014030: Beta-ketoacyl synthase-like, N-terminal (domain) [40-290]
- IPR036736: ACP-like superfamily (homologous_superfamily) [1675-1768]
- IPR057326: Ketoreductase domain (domain) [1413-1591]
- IPR014031: Beta-ketoacyl synthase, C-terminal (domain) [298-415]
- IPR013968: Polyketide synthase-like, ketoreductase domain (domain) [1413-1589]
- IPR014043: Acyl transferase domain (domain) [570-871]
- IPR050091: Polyketide and Nonribosomal Peptide Biosynthesis Enzymes (family) [37-955]
- IPR009081: Phosphopantetheine binding ACP domain (domain) [1699-1754]
- IPR016036: Malonyl-CoA ACP transacylase, ACP-binding (homologous_superfamily) [697-762]
- IPR001227: Acyl transferase domain superfamily (homologous_superfamily) [568-874]
- IPR016039: Thiolase-like (homologous_superfamily) [38-474]
Interaction partners: - L-proline--[L-prolyl-carrier protein] ligase
- AMP-binding enzyme
- AMP-binding protein
- Thioesterase PltG
- L-cysteine--[L-cysteinyl-carrier protein] ligase
- Non-ribosomal peptide synthetase PvdJ
- L-cysteine--[L-cysteinyl-carrier protein] ligase
- Polyketide synthase/nonribosomal peptide synthetase hybrid RzxA
- Non-ribosomal peptide synthetase OfaA
- Non-ribosomal peptide synthetase OfaC
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009058 (biosynthetic process), GO:0019748 (secondary metabolic process), GO:0071704 (organic substance metabolic process), GO:0044550 (secondary metabolite biosynthetic process), GO:0030638 (polyketide metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0030639 (polyketide biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm)