Protein: Protein AMEIOTIC 1 (C0RWW9)
Organism: Zea mays (Maize)
Function: Plays a fundamental role in building the proper chromosome structure at the beginning of meiosis in male meiocytes. Required for the transition from leptotene to zygotene in meiocytes. Required for homologous chromosome pairing, and initiation and progression of meiotic recombination. Regulates meiocyte cytoskeleton organization.
Subcellular location: Nucleus {ECO:0000269|PubMed:19204280}. Chromosome {ECO:0000269|PubMed:19204280}. Note=Diffuse localization in the nucleus during the initiation of meiosis. Binds to chromatin in early meiotic prophase I. {ECO:0000269|PubMed:19204280}.
Sequence: MDVETVQAGPALAAHLQLQASPKPQVKKYYFKKKTSSSHSRNGKDDVNHDSTIQPRSPLSRQSLTFDAIPTYHAGAFYEIDHDKLPPKSPIHLKSIRVVKVSECTNLDITVKFPSLQALRSFFSSYPAPGTGPELDERFVMSSNHAARILRRRVTEEELEGEVQQDSFWLIKPRLYDFAAPQQVPSRTLCLPPPPAPPAATLGLTADSCLLTTLKCDGAGWGMRRRVRYIGRHRDEAPKEASVDGYDTESSVREVQQPPATQEVKRSERNCKRKREAEASSKDNNGDEGKKNNKVQGASKKISKKAKKRTVESKDGDPRHGKDRWSAERYAAAEKSLLNIMRSRDARFGAPVMRQVLREEARKHIGDTGLLDHLLKHMAGRVPEGSVHRFRRRHNADGAMEYWLEPAELAEVRKQAGVSDPYWVPPPGWKPGDDVSLVAGDILVKRQVEELTEEVNGVKRQMEQLLCKDDGDFGAERDYSSLKEKYQRAVRANEKLEKQVLCLKDMCENVVQMNGELKKEVSAFKEKYEHIADKNDKLEEQVTYLSSSFLSFKDQLVVALKLELAPSEAVPRTALFVASGEQMTGTVIQGGQDRAERKSSFRVCKPQGKFLLPSMASGMTIGRGASSTCPAAATPGPGIPRSTSFPSMPGLPRSSRGPVEVVAAASGLDEHVMFGAHFSTPPSASSTNDAAKLQLSLPSPRSPLQPQKLFDTVTAAASGFSPQKLMHFSGLTRRDVDTSSSSSGACGSGLLEGKRVLFDADAGGISAVGTELALATPSYC
InterPro domains: - IPR044221: Protein DYAD/AMEIOTIC 1 (family) [74-747]
Interaction partners: - 26S protease regulatory subunit 7 homolog A
- 26S proteasome regulatory subunit RPN13
- 26S proteasome non-ATPase regulatory subunit 7 homolog A
- 26S proteasome non-ATPase regulatory subunit 7 homolog A
- 26S proteasome non-ATPase regulatory subunit 12 homolog B
- 26S proteasome non-ATPase regulatory subunit 12 homolog B
- 26S proteasome non-ATPase regulatory subunit 12 homolog B
- Proteasome subunit alpha type
- 26S proteasome regulatory subunit RPN7
- 26S protease regulatory subunit 8
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus), GO:0005694 (chromosome)