Protein: Gonadotropin subunit beta-2 (GTH-II-beta) (Gonadotropin beta-II chain) (GtH beta-2) (Q9DG80)
Organism: Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Function: Involved in gametogenesis and steroidogenesis.
Subcellular location: Secreted.
Sequence: MSVPASSFLLLCFLMNSFSPAQSYILPHCEPVNETVSVEKDGCPKCLVFQTAICSGHCLTKEPVYKSPFSNIYQHVCTYRDVRYETVRLPDCRPGVDPHVTYPVALSCECTLCTMDTSDCTIESLNPDFCMTQKEYILDY
InterPro domains: - IPR006208: Glycoprotein hormone subunit beta (domain) [27-130]
- IPR018245: Gonadotropin, beta subunit, conserved site (conserved_site) [54-130]
- IPR001545: Gonadotropin, beta subunit (family) [8-132]
- IPR029034: Cystine-knot cytokine (homologous_superfamily) [22-131]
Interaction partners: - Lutropin-choriogonadotropic hormone receptor
- Thyrotropin receptor
- Glycoprotein hormones alpha chain
- Nuclear transport factor 2
- Follicle-stimulating hormone receptor
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0046983 (protein dimerization activity), GO:0046982 (protein heterodimerization activity), GO:0001664 (G protein-coupled receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0065008 (regulation of biological quality), GO:0023056 (positive regulation of signaling), GO:1905954 (positive regulation of lipid localization), GO:0019222 (regulation of metabolic process), GO:0051240 (positive regulation of multicellular organismal process), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0023051 (regulation of signaling), GO:0051239 (regulation of multicellular organismal process), GO:0051050 (positive regulation of transport), GO:0048522 (positive regulation of cellular process), GO:1903530 (regulation of secretion by cell), GO:0051049 (regulation of transport), GO:0051047 (positive regulation of secretion), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0046887 (positive regulation of hormone secretion), GO:2000833 (positive regulation of steroid hormone secretion), GO:0032370 (positive regulation of lipid transport), GO:0010646 (regulation of cell communication), GO:1905952 (regulation of lipid localization), GO:0044057 (regulation of system process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010647 (positive regulation of cell communication), GO:0010817 (regulation of hormone levels), GO:0046883 (regulation of hormone secretion), GO:1903532 (positive regulation of secretion by cell), GO:2000831 (regulation of steroid hormone secretion), GO:0010628 (positive regulation of gene expression), GO:0051046 (regulation of secretion), GO:0044060 (regulation of endocrine process), GO:0032368 (regulation of lipid transport), GO:0010468 (regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)