wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Transcription cofactor vestigial-like protein 4b (Vestigial like 4 (Drosophila)) (Q6NV03)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Sequence: MLFTKMDLLNYQYLDKMNNNIGILCYEGDAALRGESRMQSLSSAVSNHRTGPPPISPSKRKHSAEQADDDIDCNSEHVAKMSRLFAAQLGKPANGDYRKDPRERSRSPIERMAAPSMSLVGGHHLYMPSLALDQPLALTKNMDSSRSMGISPTASPVERQQNRPSVITCAPANNRNCNLSHCTGSHNGCSPGLNASYRRASNSNTACDPVIEEHFRRSLGKNYKEPEPVTNSVSITGSVDDHFAKALGETWLQIKAKGGSSSPDASPNTHMVNHNHSPSLVS
InterPro domains: - IPR006627: TDU repeat (repeat) [208-251]
- IPR028184: Transcription cofactor vestigial-like protein 4 (family) [1-282]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009790 (embryo development), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:1904888 (cranial skeletal system development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048701 (embryonic cranial skeleton morphogenesis), GO:0048705 (skeletal system morphogenesis), GO:0048568 (embryonic organ development), GO:0001501 (skeletal system development), GO:0048562 (embryonic organ morphogenesis), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development), GO:0048704 (embryonic skeletal system morphogenesis), GO:0048706 (embryonic skeletal system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Right handed beta helix domain-containing protein (Q581R3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MPPKRAGSRKRKEVLPDPQTLPSGTCNYYIGEWFVNKEIDSLSDISHSVVEAHTKSNGEVSVLPRTVVLIPPATLGDVNTHYAVEVADNLRVESIPRSAVEPKPKAIPVEGEESFDPLSTREKKEEEGDSVVPDDTLPSAAAVQKVGSSEAAAEVVIQGTVHIEGIVPRIVITPDLPEPPVVPKKKKSDARKNSKRKEEEQKRLAEEARIYEEKVNAAVAAAREEEEYRMQFAHPERWPNVQFANMTFNGQVIVAHAHVKFRNCCFTSRSKDTTQLLVAQYCKVECERCTFDQPQKGSVYGWPMSNIILTECYFKGASSSRDGCTLPVANACESRPTCVGLHTDACKITVKDCEFSALGTGVIMRGTFPGSCAGQPAMSIKNCKFYGIYAAGIVLDSVNGVELAGNKVDECEYYALDCVKGEGIRVYQNTFLSKIRVQKGAHARFLNNETGTIPFTVEEVENPNWQPVY
InterPro domains: - IPR039448: Right handed beta helix domain (domain) [257-431]
- IPR011050: Pectin lyase fold/virulence factor (homologous_superfamily) [245-434]
- IPR012334: Pectin lyase fold (homologous_superfamily) [231-460]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0005930 (axoneme), GO:0005737 (cytoplasm), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0099568 (cytoplasmic region), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0005929 (cilium), GO:0032838 (plasma membrane bounded cell projection cytoplasm), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0097014 (ciliary plasm)
Protein: Methionine aminopeptidase 2 (MAP 2) (MetAP 2) (EC 3.4.11.18) (Initiation factor 2-associated 67 kDa glycoprotein) (Peptidase M) (p67) (p67eIF2) (A0A140VJE3)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03175}. Note=About 30% of expressed METAP2 associates with polysomes. {ECO:0000256|HAMAP-Rule:MF_03175}.
Sequence: MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKESGASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPICDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
InterPro domains: - IPR050247: Methionine Aminopeptidase Type 2 (family) [34-478]
- IPR036005: Creatinase/aminopeptidase-like (homologous_superfamily) [110-478]
- IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [375-448]
- IPR002468: Peptidase M24A, methionine aminopeptidase, subfamily 2 (family) [52-478]
- IPR018349: Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site (binding_site) [246-262]
- IPR001714: Peptidase M24, methionine aminopeptidase (family) [221-365]
- IPR000994: Peptidase M24 (domain) [169-372]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [373-450]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0097159 (organic cyclic compound binding), GO:0005515 (protein binding), GO:0140096 (catalytic activity, acting on a protein), GO:1901363 (heterocyclic compound binding), GO:0016787 (hydrolase activity), GO:0003676 (nucleic acid binding), GO:0008233 (peptidase activity), GO:0003723 (RNA binding), GO:0008237 (metallopeptidase activity), GO:0008238 (exopeptidase activity), GO:0004177 (aminopeptidase activity), GO:0008235 (metalloexopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:0051604 (protein maturation), GO:0043412 (macromolecule modification), GO:0006508 (proteolysis), GO:0010467 (gene expression), GO:0031365 (N-terminal protein amino acid modification), GO:0018193 (peptidyl-amino acid modification), GO:0016485 (protein processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Major pollen allergen Ole e 6 (allergen Ole e 6) (O24172)
Organism: Olea europaea (Common olive)
Function: Not known
Sequence: DEAQFKECYDTCHKECSDKGNGFTFCEMKCDTDCSVKDVKEKLENYKPKN
InterPro domains: - IPR015333: Pollen allergen ole e 6 (family) [2-48]
- IPR036466: Pollen allergen ole e 6 superfamily (homologous_superfamily) [1-50]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0016247 (channel regulator activity), GO:0140678 (molecular function inhibitor activity), GO:0016248 (channel inhibitor activity), GO:0099106 (ion channel regulator activity), GO:0008200 (ion channel inhibitor activity), GO:0015459 (potassium channel regulator activity), GO:0019870 (potassium channel inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0042742 (defense response to bacterium), GO:0050829 (defense response to Gram-negative bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Cytochrome bd-I ubiquinol oxidase subunit X (EC 7.1.1.7) (Cytochrome bd-I oxidase subunit X) (Cytochrome d ubiquinol oxidase subunit X) (P56100)
Organism: Escherichia coli (strain K12)
Function: Required for correct functioning of cytochrome bd-I oxidase. This protein and AppX may have some functional overlap.
Subcellular location: Cell inner membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Note=In sucrose cushions fractionates with both the inner and outer membranes. {ECO:0000269|PubMed:19121005, ECO:0000269|PubMed:21778229}.
Sequence: MWYFAWILGTLLACSFGVITALALEHVESGKAGQEDI
InterPro domains: - IPR011724: Cyd operon protein YbgT (family) [1-29]
- IPR012994: Membrane bound YbgT-like (family) [1-26]
Interaction partners: - Cytochrome bd-I ubiquinol oxidase subunit 2
- Cytochrome bd-I ubiquinol oxidase subunit 1
- Uncharacterized protein YnhF
- Putative cytochrome bd-II ubiquinol oxidase subunit AppX
- Cytochrome bd-II ubiquinol oxidase subunit 2
- Cytochrome bd-II ubiquinol oxidase subunit 1
- Multidrug efflux pump accessory protein AcrZ
- Uncharacterized protein YbgE
- Small protein MntS
- Cytochrome bo
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0070085 (glycosylation), GO:0044249 (cellular biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0019538 (protein metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0043413 (macromolecule glycosylation), GO:1901135 (carbohydrate derivative metabolic process), GO:0036211 (protein modification process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0009059 (macromolecule biosynthetic process), GO:0006486 (protein glycosylation), GO:0043412 (macromolecule modification), GO:0034645 (cellular macromolecule biosynthetic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0009100 (glycoprotein metabolic process), GO:0006487 (protein N-linked glycosylation), GO:0009101 (glycoprotein biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Exocrine gland secreted peptide 36 (Exocrine gland-secreting peptide 36) (A8R0W9)
Organism: Mus musculus (Mouse)
Function: Not known
Sequence: MMFFILTLPLPSMLTEGRVLPETQKEPKISADHKTNGNIVFEEIDCKNMRINIEDVGHNLQGSYQINIQFQGLFNDFLLNTCSSVSQTTNTMFIIETMNIEIFTRMSNSWNSIRHKT
InterPro domains: - IPR032253: Exocrine gland-secreted peptide Esp1/Esp22 (family) [1-82]
Interaction partners: - Olfactory receptor 5T7
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (signaling receptor activator activity), GO:0048018 (receptor ligand activity), GO:0005186 (pheromone activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0019953 (sexual reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0007276 (gamete generation), GO:0007283 (spermatogenesis), GO:0048232 (male gamete generation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Damage-inducible mutagenesis protein (Q92ZJ8)
Organism: Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Function: Not known
Sequence: MSAAVATSNPVLHELRGKIASLEGAGSRNRSILPFGVPELDAQLPGGGLAFGALHEVAGGGNGSIDGAAAALFIGGIAARTTGKVVWCLTRFDLFFPALAKVGLHPDRVIFVECYKEETVLASFEEALRYGGLGAVVAELVRLPMTASRRLQLAAEKSGTLGLVIRRWRRQTEASDFGMPTAAATRWRISVLPSEPLPVPGVGRARWLAELMRVRAGEGGEFIIGACDGQGRICLSSETANGPDQAGRSFAIGRKAAGGHRQERFEAMDFGS
InterPro domains: - IPR017026: Inducible mutagenesis protein A (family) [1-255]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [52-168]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0006950 (response to stress), GO:0009991 (response to extracellular stimulus), GO:0071496 (cellular response to external stimulus), GO:0031668 (cellular response to extracellular stimulus), GO:0033554 (cellular response to stress), GO:0006974 (cellular response to DNA damage stimulus), GO:0009432 (SOS response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0070069 (cytochrome complex), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0009579 (thylakoid)
Protein: LD24721p (MIP20650p) (Small glutamine-rich tetratricopeptide containing protein, isoform A) (Small glutamine-rich tetratricopeptide containing protein, isoform B) (Q9VJD4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MPDAVQQSFVRSFIDYLKKQGDVMSPDQTESIEVAIQCLQAAFDLGDDVEAAPAAAGEEQATTQSSSTASAPDDDAVASGSAGIGAAAAAVPNNIDMFELFQSLYTERNPESLALAESIKNEGNRLMKENKYNEALLQYNRAIAFDPKNPIFYCNRAAAHIRLGENERAVTDCKSALVYNNNYSKAYCRLGVAYSNMGNFEKAEQAYAKAIELEPDNEVYKSNLEAARNARNQPPQTGRLREDLINMLSQPMVRNLFNNAEIDVEQLLSMLQNPMIMNTIRQQFGGGNAPTLPNDMVQMIYNMTSQLTGFPNSNANPGNEQQPGNQPPPST
InterPro domains: - IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [110-246]
- IPR032374: SGTA, homodimerisation domain (domain) [6-54]
- IPR019734: Tetratricopeptide repeat (repeat) [116-217]
- IPR047150: SGT (family) [4-325]
Interaction partners: - Golgi to ER traffic protein 4 homolog
- ATPase ASNA1 homolog
- Large proline-rich protein BAG6
- Hsc70Cb, isoform G
- RE23139p1
- UV excision repair protein RAD23
- UV excision repair protein RAD23
- LD43819p
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0006457 (protein folding)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Troponin I, slow skeletal muscle (A0A060VX54)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Function: Not known
Sequence: MGDISTIGLQVQMVSLVKFFRNIGLIFGNLHCQDARASVSRKSKISASRKLMLKSLMVAKAKEEIEQEIVDKEEEKERYLAERAPTLQTGGMSFAELQELCRELHAKVDVVDEERYDIEAKVMHNTREIKDLNIKVLDLRGKFKRPSLRRVRVSADAILRSLLGSKHKVSMDLRANLKSVKKEDTEKEKTVEVSDWRKNVEAMSGMEGRKKMFDAAKGTPQ
InterPro domains: - IPR001978: Troponin (family) [50-181]
- IPR050875: Troponin I (family) [40-211]
- IPR038077: Troponin domain superfamily (homologous_superfamily) [38-189]
Interaction partners: - Troponin C, slow skeletal and cardiac muscles
- Troponin C, slow skeletal and cardiac muscles
- Troponin C, slow skeletal and cardiac muscles
- Troponin C, slow skeletal and cardiac muscles
- Troponin T type 2b
- Uncharacterized protein
- Uncharacterized protein
- Troponin T, slow skeletal muscle
- Troponin T2e, cardiac
- Troponin T2e, cardiac
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0065009 (regulation of molecular function), GO:0051098 (regulation of binding)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0036379 (myofilament), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043229 (intracellular organelle), GO:0043292 (contractile fiber), GO:0043228 (non-membrane-bounded organelle), GO:0030016 (myofibril), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0099512 (supramolecular fiber)
Protein: Radical SAM domain protein (Q72C77)
Organism: Nitratidesulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / CCUG 34227 / NCIMB 8303 / VKM B-1760 / Hildenborough) (Desulfovibrio vulgaris)
Function: Not known
Sequence: MASAHIRPRLVVADAEGNIYDHPDLLLVCRRGHEFALPRPDELMPLPEESDIFLLPGRRAVGLDPETGEAEALEELAVSAFVSPAHTLTGHPAYVSDKDAPTLPLFAYGAIGYARGRFYVCAKRVDEDKRQVFKGIPPARIKKNAHAIMQRYPDNRLMQHLMANCALTYSCPAARNLCLGRHEAPLPTSRACNARCVGCISQQEKGSKVCATPQNRMSFTPTAQEIVEVMQHHSRNEVEKPIFSFGQGCEGEPLTEARLLEESIRTFRAGGGRGTVNLNTNASLPDAVAALADAGLTSMRVSLNSAREETYGRYYRPHGYSFADVRQSIVEARKRGVFVSLNLLFFPGITDTEPETEALVELVRATGVSFIQLRNLNIDPEMYLELLEGITFGPSMGLVNFRKRLRRECPWLGFGYFNPYVGDKAELSAPMPGAWQPPSLSAALAESAEAEPEAEDFDDADLPDEALPEEAGQDGSHDDGPPSENRCSCED
InterPro domains: - IPR006638: Elp3/MiaA/NifB-like, radical SAM core domain (domain) [182-405]
- IPR013785: Aldolase-type TIM barrel (homologous_superfamily) [184-395]
- IPR034457: Organic radical-activating enzymes (family) [159-385]
- IPR007197: Radical SAM (domain) [4-426]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0019538 (protein metabolic process), GO:0036211 (protein modification process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0009059 (macromolecule biosynthetic process), GO:0043412 (macromolecule modification), GO:0034645 (cellular macromolecule biosynthetic process), GO:0042157 (lipoprotein metabolic process), GO:0045333 (cellular respiration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Tektin (Q5U3Q0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000256|RuleBase:RU367040}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000256|ARBA:ARBA00004611}.
Sequence: MGPPDRFLPSEWKHANQEHYRSSEAGRKHSEKLTAECERLIEECNKSNKRMQHDTQKRLERRIQDIKFWRQELVQKFEQMVQEIETLIIYKSRVEKALESCSEPFQVTLQCLAERQKRLAIDLVHDEVEEELLKEKEVVEGVMVLLQRTLEQINEQIRLIRSVKYYLEKDLQDKFQAENIDDFCSLLTNTSPDLNEGNSSFKYSGAAVTPEEWESLCNLNISKAEKEKNNSLSLRALVDSLLEQTARDMRRQYETTGRAFDLRIEETKTAKEQLENQLNELLAEIANQEKNQDALRLAVAEKEAPLKVAQTRLSTRSQRPNVELCHDPPQIQLLAQVKELTNHVQRLSEALELSESELKALAYNQLRLEEEIQVKTNSLYIDEVICHQLHQHITIQSF
InterPro domains: - IPR048256: Tektin-like (family) [12-393]
- IPR000435: Tektins (family) [5-392]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0006996 (organelle organization), GO:0030030 (cell projection organization), GO:0022607 (cellular component assembly), GO:0044782 (cilium organization), GO:0070925 (organelle assembly), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0060271 (cilium assembly), GO:0120031 (plasma membrane bounded cell projection assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Metallothionein B (MT-B) (P68501)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Function: Metallothioneins have a high content of cysteine residues that bind various heavy metals.
Sequence: MDPCECSKTGSCNCGGSCKCSNCACTSCKKSCCPCCPSDCSKCASGCVCKGKTCDTSCCQ
InterPro domains: - IPR018064: Metallothionein, vertebrate, metal binding site (binding_site) [12-30]
- IPR000006: Metallothionein, vertebrate (family) [1-60]
- IPR017854: Metallothionein domain superfamily (homologous_superfamily) [1-60]
- IPR023587: Metallothionein domain superfamily, vertebrate (homologous_superfamily) [1-60]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0046914 (transition metal ion binding), GO:0046870 (cadmium ion binding), GO:0008270 (zinc ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0010035 (response to inorganic substance), GO:0010038 (response to metal ion), GO:0010043 (response to zinc ion), GO:0046688 (response to copper ion), GO:0046689 (response to mercury ion), GO:0046686 (response to cadmium ion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)