Protein: ASXL transcriptional regulator 1 (A0A8M9PX23)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
Sequence: MKDKQKRKKERTWAEAARMVLENFSDAPMTPKQILHVIQTKGLKEMRSGTAPLACLVTMLHSQVRGDRVKNSIFFKLPGRMSLFTLKKNALQWTKSPSANESGDGTPTASTTSTVEGAEQESCDSTETAAASGENDASVDETSSSASCSTEPQTRLSRSSQSGRQRKKAVMMPRVVLTPLKVNGEHVPSGPMKRSRGGVEVDFETPGSILVNTNIRALINTRTFAAFPSHSQQQLLQLLPEVDRQVGPDGLARLSSSALNNEFFTHASQSWKERLAEGEFTHEMQVRFRQEMEKEKKVEAWKEKFFEEYHGQRSGLTREEALKLTMSEAGDVASPVLDSDSATVATPKRRSVGRRRREGRIRRRSRADLRRRARRTLCKTTTATVATEETTESTATPEEVPSVASPVPETTAVQGEVVLQTDPELEAPEENLSTEAVPSPVPVPTPPPASTSSTCDEPETSTRLLPEVPEPAVASTSSPSSSSSSTSSSSSPSSSPSSASDRQTFAASSDSSSSSSSSTAAVATDPLDDGASVITTGTAGTGASSRESSPAASPATSSPAIQLKEQKRRPDESQAFTSFPEKRARLDERQSFRNTVDCVHSEKPQPTTEEPKVPPIRIQLSRIKPPWVKGPPTYQICPRIVPPNEGSRRSGTGARTLADIKARAQQARAQREAAAAVAASGDGGGPGGSGPGGGTGIPDRSSGRRTREHPGPVEPGGGGGRRGGRVDLEEQESPASSHSSGAQLQLSSVDSADRPQTSTPLTEPSPSSVSSNPSLPSSESPKILALSPPATDSPASQDQVEEICGVEEVTACPSDKTSEQTLDTPVPTPSESESFCSHQDGRGEEAESSDSRTNTPVCTSSSNDAISLVPTSIPDSLPRFGAQGVDVIRTLAASSQPWEGEKKAVELHPGTTGVIQHGSDLKLPKETLVTARNGWVENREEHSMREGMLEEHRNGGSDANGKYESGSLPCLPRCAGEEDTGAHSDSTETASDFENESQEDEMVDWHGTQMDGSGMQTQNTKSLNRPVIQTSSRLTSSIVNPPQHQQPVIQAHISNQNHTQTVIQACFPNGVPNQPVIHPHKQHAINTHAINHSQDQIASAPSQAQVQAYLTQTEMDQSRNLRLNDNGNGVKLYLSEDDTKPLGREDLVLKNSAGPPVGRRVQVSSRPVSTVEANNPLVTQLLQGSLPLEKVLPQPHSASKLEINRLPGANSSNSLNPANHQTQRNLAPRFRGPPESGGPTDTVSSDFQHKTPPARVSPGPGRNFGSSPPGSAPSRMACLFEEASPRSANSQFSSQQPGGVVPPGAVPVITSLPLNSTTRTSMDMNSQNAPVYESAVIKEHPGPLSQRSETPERPSSFQQHPNNVSQSVCRNTPDAPSPPHGDLCPSEVVPTVKINWRPNKPQQPISPVATVKNEVSLRPSCQQALTKNSPAPISGNTSVVITKKEPLDGFHGGGGAMEGLLNMEMSLVRMAKKEQVKNPYTRQADTSASPVSSSPSSSASSLPFQLYGKLPKLQQSGGNGGSSSSFSYTANVSVVDGSGFTRTLADSVLQLRPRVSVGSGGGQSATLGIQAFTDSAAEEVALKCSCRLKAMIMCQGCGAFCHDDCIGPSKLCVSCLVVR
InterPro domains: - IPR026905: Protein ASX-like, PHD domain (domain) [1576-1617]
- IPR044867: DEUBAD domain (domain) [206-315]
- IPR024811: Polycomb protein ASX/ASX-like (family) [190-1619]
- IPR007759: ASXL, HARE-HTH domain (domain) [11-89]
- IPR028020: ASX, DEUBAD domain (domain) [198-312]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0061733 (peptide-lysine-N-acetyltransferase activity), GO:0016746 (acyltransferase activity), GO:0004402 (histone acetyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016407 (acetyltransferase activity), GO:0016410 (N-acyltransferase activity), GO:0010484 (histone H3 acetyltransferase activity), GO:0008080 (N-acetyltransferase activity), GO:0034212 (peptide N-acetyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009790 (embryo development), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0048513 (animal organ development), GO:1904888 (cranial skeletal system development), GO:0048731 (system development), GO:0048701 (embryonic cranial skeleton morphogenesis), GO:0048703 (embryonic viscerocranium morphogenesis), GO:0048705 (skeletal system morphogenesis), GO:0048568 (embryonic organ development), GO:0001501 (skeletal system development), GO:0048562 (embryonic organ morphogenesis), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development), GO:0048704 (embryonic skeletal system morphogenesis), GO:0048706 (embryonic skeletal system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)