Protein: Prospero homeobox 3 (Prospero-like protein Prox1b) (D2DHG1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MDSPSDRFHQQPSQMCPFELYRSLPDSNPSGHRFPPGSLSSHPLFSPLMHPNSMSQKWGSFRQRQGLFPGLLVDDDVSEEDVFGKREFGATSSSQRGSGERGQAPEPSDWGQDFARVKRLRMDSAARSEDESIREGKRGRKSRSSFRMDEKKGMEQGNRRESREGRKRQRQELKLQLEETRGKLLELQRKVWRVYGGQADDEKDQENGGINLDEVADMFSDSDDPLVGNGFSPQRCSSKKNNETNGNGNAGIFPETSVDLDLELNGSQVWLGCSLIRGEWESAEGGQKFAQALKQELANVVAQVIDRVVRLYAESDPEAVSSAQEPSMTMDLNSDRRPRPQAVEQVEALPLVTKSPQDKRAPVAQSGHKDLLLPQANPSLAPLAQPPLPALLPPRGKEHFLPSYPPDNPVHLPLLHYTMQNLFARSLSSLPLHKDCLSESFMDFRSHNSAFPPLPLLGQLDPSPSDRAREVGMRAGGAGMVDGADAALYLAAGSSQEGLSPCHLKKAKLMFFYTRYPSSSTLKTYFPDVKFNRCVTSQLIKWFSNFREFFYIQMERFARQAAREVLTSARERALRLGRDTELYRILNMHYNKSNDYQVPERFVEISEVALREFFTAIQSGRDADPCWKKSIYKIICKLDSPVPDSFRLPGCPTDTYRMG
InterPro domains: - IPR037131: Homeo-prospero domain superfamily (homologous_superfamily) [487-657]
- IPR023082: Homeo-prospero domain (domain) [496-656]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [496-649]
- IPR039350: Prospero homeodomain family (family) [10-652]
Interaction partners: - Lymphatic vessel endothelial hyaluronic receptor 1b
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0019222 (regulation of metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0030029 (actin filament-based process), GO:0048522 (positive regulation of cellular process), GO:0032989 (cellular component morphogenesis), GO:0044085 (cellular component biogenesis), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0060255 (regulation of macromolecule metabolic process), GO:0030036 (actin cytoskeleton organization), GO:0009891 (positive regulation of biosynthetic process), GO:0061061 (muscle structure development), GO:0009887 (animal organ morphogenesis), GO:0009888 (tissue development), GO:0031325 (positive regulation of cellular metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0016043 (cellular component organization), GO:0080090 (regulation of primary metabolic process), GO:0010927 (cellular component assembly involved in morphogenesis), GO:0055006 (cardiac cell development), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0055001 (muscle cell development), GO:0030239 (myofibril assembly), GO:0010468 (regulation of gene expression), GO:0022607 (cellular component assembly), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0042692 (muscle cell differentiation), GO:0072359 (circulatory system development), GO:0060537 (muscle tissue development), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0006996 (organelle organization), GO:0035051 (cardiocyte differentiation), GO:0031032 (actomyosin structure organization), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0097435 (supramolecular fiber organization), GO:0007507 (heart development), GO:0070925 (organelle assembly), GO:0014706 (striated muscle tissue development), GO:0048738 (cardiac muscle tissue development), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0055013 (cardiac muscle cell development), GO:0007010 (cytoskeleton organization), GO:0055007 (cardiac muscle cell differentiation), GO:0051146 (striated muscle cell differentiation), GO:1902680 (positive regulation of RNA biosynthetic process), GO:0055002 (striated muscle cell development), GO:0006357 (regulation of transcription by RNA polymerase II), GO:0045893 (positive regulation of DNA-templated transcription), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:0140694 (non-membrane-bounded organelle assembly), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045944 (positive regulation of transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)