wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Protein YABBY 1 (OsYABBY1) (OsYAB1) (Protein FILAMENTOUS FLOWER 1) (Q7XIM7)
Organism: Oryza sativa subsp. japonica (Rice)
Function: May play a role in floral meristem development and maintenance of stamens, rather than in determining polarity in floral organs.
Subcellular location: Nucleus {ECO:0000269|PubMed:15604733}.
Sequence: MSVQFTSEHVCYVNCNYCNTILVVNVPNNCSYNIVTVRCGHCTMVLSMDLAPFHQARTVQDHQVQNRGFQGNNFGSYDIASRNQRTSTAMYPMPTSQQQVSPIRPPEKRQRVPSAYNRFIKEEIQRIKTSNPEISHREAFSAAAKNWAHLPRLHFGLSVADGGGGGGSN
InterPro domains: - IPR056776: YABBY, N-terminal domain (domain) [6-63]
- IPR006780: YABBY protein (family) [6-159]
- IPR036910: High mobility group box domain superfamily (homologous_superfamily) [91-153]
- IPR056775: YABBY protein, C-terminal domain (domain) [98-156]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0050793 (regulation of developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0007389 (pattern specification process), GO:0050794 (regulation of cellular process), GO:2000024 (regulation of leaf development), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0009798 (axis specification), GO:0080090 (regulation of primary metabolic process), GO:0048509 (regulation of meristem development), GO:0003002 (regionalization), GO:0065001 (specification of axis polarity), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0009955 (adaxial/abaxial pattern specification), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0010468 (regulation of gene expression), GO:0009943 (adaxial/abaxial axis specification), GO:0009944 (polarity specification of adaxial/abaxial axis), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Proliferating cell nuclear antigen (PCNA) (Q9PTP1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:P12004}.
Sequence: MFEARLVQGSILKKVLEALKDLITEACWDVSSSGISLQSMDSSHVSLVQLTLRSDGFDSYRCDRNLAMGVNLSSMSKILKCAGNEDIITLRAEDNADALALVFETLNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSQIGDAVMISCAKDGVKFSASGELGTGNIKLSQTSNVDKEDEAVTIEMNEPVQLIFALNYLNFFTKATPLSKTVTLSMSADIPLVVEYKIADMGHVKYYLAPKIDEESS
InterPro domains: - IPR046938: DNA clamp superfamily (homologous_superfamily) [1-255]
- IPR000730: Proliferating cell nuclear antigen, PCNA (family) [1-259]
- IPR022648: Proliferating cell nuclear antigen, PCNA, N-terminal (domain) [1-124]
- IPR022649: Proliferating cell nuclear antigen, PCNA, C-terminal (domain) [127-254]
- IPR022659: Proliferating cell nuclear antigen, PCNA, conserved site (conserved_site) [34-79]
Interaction partners: - Replication factor C
- Replication factor C
- Polymerase
- DNA polymerase.
- Replication factor C
- DNA mismatch repair protein
- Activator 1 subunit 5
- DNA polymerase eta
- DNA ligase
- Replication factor C subunit 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0060322 (head development), GO:0009887 (animal organ morphogenesis), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0048854 (brain morphogenesis), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Ubinuclein 1 (K7EJT1)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: XSDEEEDEEKGGRRIMGPRKKFQWNDEIRTLFKESRRGHGHLTSILAKKKVMAPSKIKVKESSTKPDKKVSVPSGQIGGPIALPSDHQTGGLSIGASSRELPSQASGGLANPPPVNLEDSLDEDLIRNPASSVEAVSKELAALNSRAAGNSEFTLPAPSKAPAEKVGGVLCTEEKRNFAKPSPSAPPPASSLQSPLNFLAEQALALGQSSQEKKPESSGYKELSCQAPLNKGLPEVHQSKAKHHSLPRTSHGPQVAVPVPGPQVKVFHAGTQQQKNFTPPSPFANKLQGPKASPTQCHRSLLQLVKTAAKGQ
InterPro domains: - IPR026947: Ubinuclein middle domain (domain) [2-34]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0048523 (negative regulation of cellular process), GO:0009892 (negative regulation of metabolic process), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0051252 (regulation of RNA metabolic process), GO:0051253 (negative regulation of RNA metabolic process), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:0010468 (regulation of gene expression), GO:2001141 (regulation of RNA biosynthetic process), GO:1902679 (negative regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0006357 (regulation of transcription by RNA polymerase II), GO:1903507 (negative regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045892 (negative regulation of DNA-templated transcription), GO:0000122 (negative regulation of transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Uncharacterized protein (Q38BV9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MSTPKCTKQSINRKRGQGTSGLKASALVATADQGDPPPFSPSLELTFRGHRSTVLAASFRPTAVSYSYSSLDGRGSPENVWSSPCILSGGADGYVFMWSARPTVRALRFVGPHSPVRDCAWSSHGQLLASAGHDGFVRLWLPMLRRTSGLTGSSSSGGGCVGSGGENCYLWRAHEGPVRALAAAPYDDYLYTAGDDKSVKCWDLNYSPTRSSSSGKSGGHKFVCGFVGGHQNWVRTVAVSNGMSALPSHGPLVASGGDDRTVQVWDPRSRRPTHTFYEHTDSVRSVDFHPDGCSIATGSSDHTINVYDLRLNRLLQHYGAHDGAVNEVRFAPTGSWLLSASADGTAKLWDLKEGYLYCTLSAHEGGVYTSRFSDDSRHLVTAGQDGLVMMWRTGLLRTQPVYATHFYAGKCPPVGAATEPLPLPAATSINTEPRPEDGFDHTHLADSTVVNREGRRCGSRDAKELGTCLARSRRNSTDVVSGHRTSEGKRPNVGVAKSKLGNRATFSVASSQNSAVSSQRPPLAQPSLQAGGSAAAAAMAVSAEIDDCPFAACLRNDVCNGVGSGNSIAQSFSRSERRERTPVKPKTETHNGSEEFSVPNEAFHTVSMKVSVSDGGHQQGEENQRRLQPQERHHPLPTNAQVTSAVGVEGSLRGNTSGVGEEDEEMCVVEYIDDASGEARYNGWMNCAESASHHVDHSMLSRKGDEHNMNARLERLEKAYARLAEEVQVSQRHTVEVVQKQQENWELQRQQQRAEMEQLRVMMAGLVAQQDALLEALRKA
InterPro domains: - IPR001680: WD40 repeat (repeat) [40-392]
- IPR019775: WD40 repeat, conserved site (conserved_site) [337-351]
- IPR020472: PAC1/LIS1-like, WD-40 repeat (repeat) [190-351]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [22-411]
- IPR050505: WD repeat-containing protein 55/POC1 (family) [49-394]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [40-392]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: DNA-binding transcriptional repressor TubR (Q8KNP2)
Organism: Bacillus thuringiensis subsp. israelensis
Function: A DNA-binding protein that is part of the type III plasmid partition system used to ensure correct segregation of the pBtoxis plasmid. Cooperatively binds to the centromere-like site (tubC), which may seed filament formation by the TubZ polymerizing GTPase, stabilizing TubZ filaments. TubR-tubC complexes track the depolymerizing minus end of the filament, probably pulling plasmid within the cell. Required for plasmid replication. Negatively regulates levels of TubZ; its effect on RNA expression has not been shown (Probable). Specifically binds iterons, 12-bp imperfect direct repeats that function as a plasmid origin of replication. Four TubR dimers bind to tubC, forming an extended bent DNA-protein filament with protein wrapping helically around the outside of the DNA.
Sequence: MNRDHFYTLNIAEIAERIGNDDCAYQVLMAFINENGEAQMLNKTAVAEMIQLSKPTVFATVNSFYCAGYIDETRVGRSKIYTLSDLGVEIVECFKQKAMEMRNL
InterPro domains: - IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [27-101]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [4-104]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0010941 (regulation of cell death), GO:0010942 (positive regulation of cell death), GO:0043067 (regulation of programmed cell death), GO:0043068 (positive regulation of programmed cell death), GO:0043065 (positive regulation of apoptotic process), GO:0042981 (regulation of apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0032993 (protein-DNA complex)
Protein: AT07759p (Q8IHF3)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: HGCHGVCCRWQDSLTICPKFLISGGAEGAIYLWDIETGARLQEIVQKGTEYVTISCSTNDPLTIYAGTSIGTIREFQDSTLVREITIPSRTKGSVSDVCLARSDLIMFVADHEGNLFNMQLPFLEAGGGTFTNFRFFDGPVNKLRFSYDGTLLFAISNKGTLAIWAMDNIEGKVPYMDQDLMRSQEVLIPRSQLNDKIEQIANLELRLKQQAEEFQYQLSQNEIFDGQQLQEVHRSYCSALEELKELNNEIEARHTEEMNHITFQINSIREEHRIQLDTLATQYSERMLIEYQKFTNLRENMLELRESYEDKLKNSTGTLQDTVEALENNYKQQLNERKELIRDLMKEMQDKKAEFIEYCREVELENDRNMVSTQTEYENKLTTERNETQMWRGKAGVLQKKFESQSREIDNLLEEVEILKEEHHKSQRNIQKQMRNIEDLQKDIADRDYAINGKEKRIQDLLHKNQELDKYKQVLGHKIAELKAQIEPREFQINDKRKHIIEMEAELEGLNQNNVQLELQLKEMRDKYLSNVAELRTERHRAKASRECLHSICSDIYYVAGEINSAEALKKAVKELFRKHASDDELKRFVTLDAEVRDEFMRQRRQIENVLDRYKSVAEDKSVQKKYDKLFKENVILIEEIEKLNETNKMLRSKVKEDLRRSTKTIHK
InterPro domains: - IPR052993: Cilia- and flagella-associated protein 57 (family) [19-660]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [5-277]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [17-169]
- IPR001680: WD40 repeat (repeat) [20-43]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0003008 (system process), GO:0050877 (nervous system process), GO:0007600 (sensory perception), GO:0050954 (sensory perception of mechanical stimulus), GO:0007605 (sensory perception of sound)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0005930 (axoneme), GO:0005737 (cytoplasm), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0099568 (cytoplasmic region), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0005929 (cilium), GO:0032838 (plasma membrane bounded cell projection cytoplasm), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0097014 (ciliary plasm)
Protein: FI01423p (Glutathione S transferase E3 (EC 2.5.1.18)) (A1ZB68)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MGKLTLYGIDGSPPVRSVLLTLRALNLDFDYKIVNLMEKEHLKPEFLKINPLHTVPALDDNGFYLADSHAINSYLVSKYGRNDSLYPKDLKKRAIVDQRLHYDSSVVTSTGRAITFPLFWENKTEIPQARIDALEGVYKSLNLFLENGNYLAGDNLTIADFHVIAGLTGFFVFLPVDATKYPELAAWIKRIKELPYYEEANGSRAAQIIEFIKSKKFTIV
InterPro domains: - IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [1-88]
- IPR036282: Glutathione S-transferase, C-terminal domain superfamily (homologous_superfamily) [86-204]
- IPR004046: Glutathione S-transferase, C-terminal (domain) [130-195]
- IPR010987: Glutathione S-transferase, C-terminal-like (domain) [89-217]
- IPR004045: Glutathione S-transferase, N-terminal (domain) [2-83]
Interaction partners: - Glutathione S transferase E7
- Glutathione S-transferase D2
- Bifunctional glutamate/proline--tRNA ligase
- Glutathione S transferase T1
- Glutathione S transferase E9
- Glutathione S transferase O3
- Glutathione S transferase E6
- Glutathione S transferase D10, isoform A
- NADP-retinol dehydrogenase
- Glutathione S-transferase D4
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups), GO:0004364 (glutathione transferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0071704 (organic substance metabolic process), GO:0006749 (glutathione metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0042579 (microbody), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005777 (peroxisome)
Protein: Guanidinobutyrase (EC 3.5.3.7) (Q9I3S3)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Catalyzes specifically the hydrolysis of 4-guanidinobutanoate to 4-aminobutanoate and urea. Has no activity against arginine, agmatine, 3-guanidinopropionate and guanidinoacetate.
Sequence: MDKNLHQPLGGNEMPRFGGIATMMRLPHVQSPAELDALDAAFVGVPLDIGTSLRSGTRFGPREIRAESVMIRPYNMATGAAPFDSLNVADIGDVAINTFNLLEAVRIIEQEYDRILGHGILPLTLGGDHTITLPILRAIKKKHGKVGLVHVDAHADVNDHMFGEKIAHGTTFRRAVEEDLLDCDRVVQIGLRAQGYTAEDFNWSRKQGFRVVQAEECWHKSLEPLMAEVREKVGGGPVYLSFDIDGIDPAWAPGTGTPEIGGLTTIQAMEIIRGCQGLDLIGCDLVEVSPPYDTTGNTSLLGANLLYEMLCVLPGVVRR
InterPro domains: - IPR023696: Ureohydrolase domain superfamily (homologous_superfamily) [4-313]
- IPR005925: Agmatinase-related (family) [34-311]
- IPR020855: Ureohydrolase, manganese-binding site (binding_site) [241-262]
- IPR006035: Ureohydrolase (family) [12-319]
Interaction partners: - Probable sodium:solute symport protein
- SnoaL-like domain-containing protein
- Aliphatic amidase
- Probable transporter
- Probable aldehyde dehydrogenase
- Probable aldehyde dehydrogenase
- aldehyde dehydrogenase
- Bifunctional protein PutA
- Amidase domain-containing protein
- Probable amidase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0016813 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0009308 (amine metabolic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0006576 (biogenic amine metabolic process), GO:0009309 (amine biosynthetic process), GO:0042401 (biogenic amine biosynthetic process), GO:0006595 (polyamine metabolic process), GO:0006596 (polyamine biosynthetic process), GO:0008216 (spermidine metabolic process), GO:0008295 (spermidine biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Serine/threonine-protein kinase KIN4 (EC 2.7.11.1) (Q01919)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: This protein is probably a serine/threonine protein kinase.
Sequence: MASVPKRHTYGGNVVTDRDRHSLQRNNEILHPIHKNQRKHATFGPYIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGFVNEFFEDNELMKTSCGSPCYAAPELVVSTKAYEARKADVWSCGVILYAMLAGYLPWDDDHENPTGDDIARLYKYITQTPLKFPEYITPIPRDLLRRILVPNPRRRINLQTIKRHVWLKPHEAFLSIQPNYWDEHLQKERPKPPNKGDVGRHSTYSSSASSYSKSRDRNSLIIESTLEQHRMSPQLATSRPASPTFSTGSKVVLNDTKNDMKESNINGERTSASCRYTRDSKGNGQTQIEQVSARHSSRGNKHTSVAGLVTIPGSPTTARTRNAPSSKLTEHVKDSSQTSFTQEEFHRIGNYHVPRSRPRPTSYYPGLSRNTADNSLADIPVNKLGSNGRLTDAKDPVPLNAIHDTNKATISNNSIMLLSEGPAAKTSPVDYHYAIGDLNHGDKPITEVIDKINKDLTHKAAENGFPRESIDPESTSTILVTKEPTNSTDEDHVESQLENVGHSSNKSDASSDKDSKKIYEKKRFSFMSLYSSLNGSRSTVESRTSKGNAPPVSSRNPSGQSNRSNIKITQQQPRNLSDRVPNPDKKINDNRIRDNAPSYAESENPGRSVRASVMVSTLREENRSELSNEGNNVEAQTSTARKVLNFFKRRSMRV
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [43-371]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [171-183]
- IPR017441: Protein kinase, ATP binding site (binding_site) [52-80]
- IPR000719: Protein kinase domain (domain) [46-313]
- IPR034674: Serine/threonine-protein kinase Kin4/ppk1, catalytic domain (domain) [44-313]
Interaction partners: - Mitotic check point protein BFA1
- Guanine nucleotide exchange factor LTE1
- Mitotic check point protein BUB2
- Protein TEM1
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform
- Karyogamy protein KAR9
- Gamma tubulin complex adapter SPC72
- Sporulation-specific protein 12
- Protein NUD1
- Tyrosine-protein phosphatase CDC14
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0006793 (phosphorus metabolic process), GO:0036211 (protein modification process), GO:0006796 (phosphate-containing compound metabolic process), GO:0043412 (macromolecule modification), GO:0006468 (protein phosphorylation), GO:0016310 (phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)