Protein: Tehao (Q58S71)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Sequence: VVCTNDEACQYKSAEWQCDPRCICWVQRSVGSLIVDCRGTSLEELPDLPRTTLLSTVLKVGNNSLTSLPTVSEHSGYANVSGLFLSDNNLTSLGSGDQLPDNLTHLDVRDNQIQSLSEEFLLFLQEPNNTMTLSLSGNPITCGCESLSLLFFVRTNPQRVRDIADIVCTKQKKSFQQMEAFELCPSYVLLISCVVGGLVIVICLLTVFYLMFQQELKIWLYNNNLCLWWVSEEELDKDKTYDAFISYSHKDEELISKLLPKLESGPHPFRLCLHDRDWLVGDCIPEQIVRTVDDSKRVIIVLSQHFIDSVWARMEFRIAYQATLQDKRKRIIIILYRELEHMNG
InterPro domains: - IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [2-188]
- IPR035897: Toll/interleukin-1 receptor homology (TIR) domain superfamily (homologous_superfamily) [230-343]
- IPR000157: Toll/interleukin-1 receptor homology (TIR) domain (domain) [239-344]
- IPR001611: Leucine-rich repeat (repeat) [102-123]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0005488 (binding), GO:0038023 (signaling receptor activity), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0005102 (signaling receptor binding), GO:0015026 (coreceptor activity), GO:0019900 (kinase binding), GO:0019901 (protein kinase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0009605 (response to external stimulus), GO:0048522 (positive regulation of cellular process), GO:0048584 (positive regulation of response to stimulus), GO:0019222 (regulation of metabolic process), GO:0009607 (response to biotic stimulus), GO:0006955 (immune response), GO:0002684 (positive regulation of immune system process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0009893 (positive regulation of metabolic process), GO:0051716 (cellular response to stimulus), GO:0002682 (regulation of immune system process), GO:0006950 (response to stress), GO:0051707 (response to other organism), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0002831 (regulation of response to biotic stimulus), GO:0032103 (positive regulation of response to external stimulus), GO:0050776 (regulation of immune response), GO:0043207 (response to external biotic stimulus), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0031325 (positive regulation of cellular metabolic process), GO:0002702 (positive regulation of production of molecular mediator of immune response), GO:0002697 (regulation of immune effector process), GO:0002833 (positive regulation of response to biotic stimulus), GO:0080134 (regulation of response to stress), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0006952 (defense response), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0050778 (positive regulation of immune response), GO:0032101 (regulation of response to external stimulus), GO:0002700 (regulation of production of molecular mediator of immune response), GO:0031323 (regulation of cellular metabolic process), GO:0007166 (cell surface receptor signaling pathway), GO:0031349 (positive regulation of defense response), GO:0002699 (positive regulation of immune effector process), GO:0045087 (innate immune response), GO:0009891 (positive regulation of biosynthetic process), GO:0098542 (defense response to other organism), GO:0031347 (regulation of defense response), GO:0002784 (regulation of antimicrobial peptide production), GO:0034248 (regulation of amide metabolic process), GO:0002759 (regulation of antimicrobial humoral response), GO:0034250 (positive regulation of amide metabolic process), GO:0002922 (positive regulation of humoral immune response), GO:0031326 (regulation of cellular biosynthetic process), GO:0002760 (positive regulation of antimicrobial humoral response), GO:0010628 (positive regulation of gene expression), GO:0002920 (regulation of humoral immune response), GO:0002225 (positive regulation of antimicrobial peptide production), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0010468 (regulation of gene expression), GO:0008063 (Toll signaling pathway), GO:0002805 (regulation of antimicrobial peptide biosynthetic process), GO:0002807 (positive regulation of antimicrobial peptide biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098552 (side of membrane), GO:0009986 (cell surface), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0009897 (external side of plasma membrane), GO:0005886 (plasma membrane)