wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: TGFB-induced factor homeobox 1 (A0A8I5ZTL5)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108}.
Sequence: MTLLLGSATLERGTGDLGPRTRAVQLEGVVAAASGSDSEDEDSMDSPLDLSSSAASGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFTISRRGAKISEASSIEAAMGIKNFMPTLEESPFHSCVVGPNPTLGRPVSPKPPSPGPILARPSVICHTTVTALKDGPFSLCQAVSVGHSTDVQQVAPSNFTDASLRYPEDTCKSGPSPNPQSGLFNTPPPTPPDLNQDFSGFQLLVDVALKQAAEMELQAKLTA
InterPro domains: - IPR001356: Homeodomain (domain) [56-123]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [58-130]
- IPR008422: KN homeodomain (domain) [76-115]
- IPR050224: Three Amino acid Loop Extension (TALE) homeobox (family) [42-136]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0046332 (SMAD binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0009719 (response to endogenous stimulus), GO:0009892 (negative regulation of metabolic process), GO:0071495 (cellular response to endogenous stimulus), GO:0060255 (regulation of macromolecule metabolic process), GO:0009410 (response to xenobiotic stimulus), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0070848 (response to growth factor), GO:0010629 (negative regulation of gene expression), GO:0071363 (cellular response to growth factor stimulus), GO:0010468 (regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Interleukin-1 (Q9PT12)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Function: Not known
Subcellular location: Cytoplasm, cytosol {ECO:0000256|ARBA:ARBA00004514}. Lysosome {ECO:0000256|ARBA:ARBA00004371}. Secreted, extracellular exosome {ECO:0000256|ARBA:ARBA00004550}.
Sequence: MEFESNCSLMKNTSASVAWSSKLPQGLDVEISHHPITLRCVANLIIAMERLNGGKGFTLGRDEGLLNFLLESAVEVLELESARTEASSRAAFSSKGEYECSVTDSENKCWVLNEGSMELHAIMLQGGSSYHKVHLNLSTYITPVPSETKARPVALGIKGSNLYLSCITSEGTPTLHLEEVADKEQLKSINHESDMVRFLFYKQDTGVDISTLESAHYRNWFISTALQQDNTKMVNMCQRATLNRNTTFTIQRHN
InterPro domains: - IPR008996: Cytokine IL1/FGF (homologous_superfamily) [98-252]
- IPR000975: Interleukin-1 family (family) [36-253]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (signaling receptor activator activity), GO:0048018 (receptor ligand activity), GO:0005125 (cytokine activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0009893 (positive regulation of metabolic process), GO:0019222 (regulation of metabolic process), GO:0009892 (negative regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0010628 (positive regulation of gene expression), GO:0010629 (negative regulation of gene expression), GO:0010468 (regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Alpha-2-HS-glycoprotein (Fetuin-A) (B0JYN6)
Organism: Bos taurus (Bovine)
Function: Not known
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Sequence: MKSFVLLFCLAQLWGCHSIPLDPVAGYKEPACDDPDTEQAALAAVDYINKHLPRGYKHTLNQIDSVKVWPRRPTGEVYDIEIDTLETTCHVLDPTPLANCSVRQQTQHAVEGDCDIHVLKQDGQFSVLFTKCDSSPDSAEDVRKLCPDCPLLAPLNDSRVVHAVEVALATFNAESNGSYLQLVEISRAQFVPLPVSVSVEFAVAATDCIAKEVVDPTKCNLLAEKQYGFCKGSVIQKALGGEDVRVTCTLFQTQPVIPQPQPDGAEAEAPSAVPDAAGPTPSAAGPPVASVVVGPSVVAVPLPLHRAHYDLRHTFSGVASVESSSGEAFHVGKTPIVGQPSIPGGPVRLCPGRIRYFKI
InterPro domains: - IPR001363: Proteinase inhibitor I25C, fetuin, conserved site (conserved_site) [32-149]
- IPR025760: Fetuin-A-type cystatin domain (domain) [27-256]
- IPR050735: Kininogen/Fetuin/Histidine-rich Glycoprotein (family) [1-269]
- IPR046350: Cystatin superfamily (homologous_superfamily) [27-238]
- IPR000010: Cystatin domain (domain) [23-249]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0032501 (multicellular organismal process), GO:0050793 (regulation of developmental process), GO:0001503 (ossification), GO:0051241 (negative regulation of multicellular organismal process), GO:0051239 (regulation of multicellular organismal process), GO:0051093 (negative regulation of developmental process), GO:2000026 (regulation of multicellular organismal development), GO:0030279 (negative regulation of ossification), GO:0030278 (regulation of ossification), GO:0070168 (negative regulation of biomineral tissue development), GO:0070167 (regulation of biomineral tissue development), GO:0030500 (regulation of bone mineralization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005576 (extracellular region), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043230 (extracellular organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0031982 (vesicle)
Protein: NAD(P)H quinone oxidoreductase PST3 (EC 1.6.5.2) (Flavodoxin-like protein PST3) (FLP PST3) (A0A1D8PT02)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Subcellular location: Cell membrane {ECO:0000269|PubMed:26325183}; Peripheral membrane protein {ECO:0000269|PubMed:26325183}.
Sequence: MAPKVAIIIYSLYHHIAQLAEEEKKGIEAAGGVADIYQVPETLSDDVLKLLHAPAKPNYPIATNDTLTGYDAYLFGIPTRFGNYPAQFKAFWDATGGLWAQGALAGKQAGIFVSTSGQGGGQETTAVNALSVLVHHGIIFVPLGYAKAFPLQTNLEEIHGGSPYGAGTFAGVDGSRQPTKLEKEIAFIQGKSFYETVSK
InterPro domains: - IPR029039: Flavoprotein-like superfamily (homologous_superfamily) [1-199]
- IPR005025: NADPH-dependent FMN reductase-like domain (domain) [18-144]
- IPR008254: Flavodoxin/nitric oxide synthase (domain) [5-193]
- IPR010089: Flavoprotein WrbA-like (family) [4-193]
Interaction partners: - NAD
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016651 (oxidoreductase activity, acting on NAD(P)H), GO:0016655 (oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor), GO:0003955 (NAD(P)H dehydrogenase (quinone) activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0006979 (response to oxidative stress), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0034599 (cellular response to oxidative stress), GO:0062197 (cellular response to chemical stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: ornithine decarboxylase (EC 4.1.1.17) (Q9DGJ4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Sequence: MTACTGSDFDFAFLEEGFCARDIVEQKINESSLSDDKDAFYVADLGDVLKKHLRWLRVLPRITPFYAVKCNDSRAVVTTLASLGAGFDCASKTEIQIVQSVGVDPSRIIYANPCKQVSQIKYASAHGVQMMTFDSEVELMKVARSHENAKLVLRIATDDSKAVCRLSVKFGATLKSSRLLLERAKELGLDVIGVSFHVGSGCTDPETYSQAISDARYVFDIGAELGYNMSLLDIGGGFPGSEDTKLKFEEIAAVINPALDKYFPVDSGVRIIAEPGRYYVASAYTLAVNIIAKKVIMKEQSASDEEEDVSNDRTLMYYVNDGVYGSFNCILYDHAHVLPTLHKKPKPDERMYPCSIWGPTCDGLDRIVEQCSLPDMQVGDWLLFENMGAYTVAASSTFNGFQKPDIYYIMSRTAWQCMQQIRAQGIPALPLEEPSAGNVPSHCGRESSLDVPAKPCPTQVL
InterPro domains: - IPR029066: PLP-binding barrel (homologous_superfamily) [44-283]
- IPR022657: Orn/DAP/Arg decarboxylase 2, conserved site (conserved_site) [222-239]
- IPR022644: Orn/DAP/Arg decarboxylase 2, N-terminal (domain) [45-281]
- IPR022643: Orn/DAP/Arg decarboxylase 2, C-terminal (domain) [282-388]
- IPR009006: Alanine racemase/group IV decarboxylase, C-terminal (homologous_superfamily) [35-420]
- IPR002433: Ornithine decarboxylase (family) [29-411]
- IPR000183: Ornithine/DAP/Arg decarboxylase (family) [66-401]
- IPR022653: Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site (binding_site) [66-84]
Interaction partners: - Spermidine synthase
- Ornithine decarboxylase antizyme 1
- Agmatine ureohydrolase
- Ornithine aminotransferase
- Arginase
- Arginase
- Diamine acetyltransferase 1
- Diamine acetyltransferase 1
- Ornithine decarboxylase antizyme 2
- Ornithine decarboxylase antizyme
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016830 (carbon-carbon lyase activity), GO:0016831 (carboxy-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0009308 (amine metabolic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0006576 (biogenic amine metabolic process), GO:0009309 (amine biosynthetic process), GO:0042401 (biogenic amine biosynthetic process), GO:0006595 (polyamine metabolic process), GO:0009445 (putrescine metabolic process), GO:0006596 (polyamine biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1) (P04692)
Organism: Rattus norvegicus (Rat)
Function: Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:7568216}. Note=Associates with F-actin stress fibers (PubMed:7568216). {ECO:0000269|PubMed:7568216}.
Sequence: MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
InterPro domains: - IPR000533: Tropomyosin (family) [67-283]
Interaction partners: - Troponin T, cardiac muscle
- Troponin I, cardiac muscle
- Actin, alpha cardiac muscle 1
- Myosin light chain 1/3, skeletal muscle isoform
- Troponin T, fast skeletal muscle
- Myosin-6
- Myosin regulatory light chain 11
- Troponin T, slow skeletal muscle
- Myosin light chain 3
- Myosin regulatory light chain 2, ventricular/cardiac muscle isoform
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0051015 (actin filament binding), GO:0042802 (identical protein binding), GO:0008092 (cytoskeletal protein binding), GO:0046983 (protein dimerization activity), GO:0042803 (protein homodimerization activity), GO:0046982 (protein heterodimerization activity), GO:0003779 (actin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0003008 (system process), GO:0003012 (muscle system process), GO:0006936 (muscle contraction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015629 (actin cytoskeleton)
Protein: peptidoglycan lytic exotransglycosylase (EC 4.2.2.n1) (Murein hydrolase A) (Q9JPQ6)
Organism: Neisseria meningitidis
Function: Not known
Sequence: MKKYLFRAALCGIAAAILAACQSKSIQTFPQPDTSVINGPGRPVGIPDPAGTTVGGGGAVYTVVPHLSLPHWAAQDFAKSLQSFRLGCANLKNRQGWQDVCAQAFQTPVHSFQAKQFFERYFTPWQVAGNGSLAGTVTGYYEPVLKGDDRRTAQARFPIYGIPDDFISVPLPAGLRSGKALVRIRQTGKNSGTIDNTGGTHTADLSQFPITARTTAIKGRFEGSRFLPYHTRNQINGGALDGKAPILGYAEDPVELFFMHIQGSGRLKTPSGKYIRIGYADKNEHPYVSIGKYMADKGYLKLGQTSMQGIKSYMRQNPQRLAEVLGQNPSYIFFRELTGSSNDGPVGALGTPLMGEYAGAVDRHYITLGAPLFVATAHPVTRKALNRLIMAQDTGSAIKGAVRVDYFWGYGDEAGELAGKQKTTGYVWQLLPNGMKPEYRP
InterPro domains: - IPR005300: Lytic transglycosylase MltA, domain B (domain) [137-335]
- IPR026044: Membrane-bound lytic murein transglycosylase A (family) [1-441]
- IPR010611: 3D domain (domain) [359-430]
- IPR036908: RlpA-like domain superfamily (homologous_superfamily) [51-439]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0061783 (peptidoglycan muralytic activity), GO:0016829 (lyase activity), GO:0016835 (carbon-oxygen lyase activity), GO:0016837 (carbon-oxygen lyase activity, acting on polysaccharides)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901575 (organic substance catabolic process), GO:0043170 (macromolecule metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0009057 (macromolecule catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:1901136 (carbohydrate derivative catabolic process), GO:0006022 (aminoglycan metabolic process), GO:0006026 (aminoglycan catabolic process), GO:0030203 (glycosaminoglycan metabolic process), GO:0006027 (glycosaminoglycan catabolic process), GO:0000270 (peptidoglycan metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0031975 (envelope), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030312 (external encapsulating structure), GO:0009279 (cell outer membrane), GO:0019867 (outer membrane), GO:0030313 (cell envelope)
Protein: Transmembrane protein, putative (DUF3317) (F4IPU5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004477}.
Sequence: MNWVQRKIYLYNVTFGLYMLDWWERYLFNSLVLILMWFILYNGSRYFSELCKRHLS
InterPro domains: - IPR024512: Small subunit of serine palmitoyltransferase-like (family) [1-52]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0065009 (regulation of molecular function), GO:0050790 (regulation of catalytic activity), GO:0044093 (positive regulation of molecular function), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0048229 (gametophyte development), GO:0080090 (regulation of primary metabolic process), GO:0044087 (regulation of cellular component biogenesis), GO:0009555 (pollen development), GO:0010556 (regulation of macromolecule biosynthetic process), GO:1905038 (regulation of membrane lipid metabolic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0051338 (regulation of transferase activity), GO:0043085 (positive regulation of catalytic activity), GO:0019216 (regulation of lipid metabolic process), GO:0090153 (regulation of sphingolipid biosynthetic process), GO:0046890 (regulation of lipid biosynthetic process), GO:0051347 (positive regulation of transferase activity)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: RELA proto-oncogene, NF-kB subunit (E9PQS6)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MDEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCD
InterPro domains: - IPR000451: NF-kappa-B/Dorsal (family) [4-208]
- IPR037059: Rel homology domain (RHD), DNA-binding domain superfamily (homologous_superfamily) [1-176]
- IPR008967: p53-like transcription factor, DNA-binding domain superfamily (homologous_superfamily) [9-187]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [177-208]
- IPR014756: Immunoglobulin E-set (homologous_superfamily) [182-208]
- IPR011539: Rel homology domain, DNA-binding domain (domain) [7-181]
- IPR030492: Rel homology domain, conserved site (conserved_site) [25-31]
- IPR030495: Transcription factor p65, RHD domain, N-terminal (domain) [10-178]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023056 (positive regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010647 (positive regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0010646 (regulation of cell communication), GO:1902533 (positive regulation of intracellular signal transduction), GO:1902531 (regulation of intracellular signal transduction), GO:0043123 (positive regulation of I-kappaB kinase/NF-kappaB signaling), GO:0043122 (regulation of I-kappaB kinase/NF-kappaB signaling)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Isotocin (Oxytocin-neurophysin 1 precursor) (Q8UUT8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Sequence: MSGGLLSAAALLCLLSVCSACYISNCPIGGKRSVQDWPIRQCMPCGPGDRGRCFGPSICCGEGIGCLVGSPETLRCLEEDFLPSPCEMSGKACGYEGRCAAPGVCCDSEGCSVDQSCVDGDADAAAVNQPANSPDLLLKLLHLSSHTHPSRIHQ
InterPro domains: - IPR022423: Neurohypophysial hormone, conserved site (conserved_site) [21-29]
- IPR036387: Neurohypophysial hormone domain superfamily (homologous_superfamily) [34-126]
- IPR000981: Neurohypophysial hormone (family) [3-151]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (signaling receptor activator activity), GO:0048018 (receptor ligand activity), GO:0005179 (hormone activity), GO:0005184 (neuropeptide hormone activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)