Protein: t-SNARE family protein (Q55DR2)
Organism: Dictyostelium discoideum (Social amoeba)
Subcellular location: Membrane; Single- pass type IV membrane protein
Sequence: MEDRLQELRIAGGLKPLVDKKNGKKGSMVEISLETPSSSKIYDYNENKNGDIELEINDHPDPVEEFMPEFYQEVGLIKSLMTSVKKNIRAIEDKYILSLNSISIESQNQKYEDDIQLILEVTNSSLSELKNKLDTMKISNEKYSYSKSSTPTEVRIRNSMLNTLTQKFIEMMREYQEIQNNYKNKYKEKIERQYKIVKPEATSQEINDAIQSGDSKKIFEETILHTHLHTHALNALDYIQERHNDIIKLEQSIKELHQLFLDMAVLVHNQGELLNVIEDNINSAVSDTREGTQNLQEANKLHKKSRKKMYILLIIVSIVLVIILVPILSTQINK
InterPro domains: - IPR045242: Syntaxin (family) [66-319]
- IPR010989: SNARE (homologous_superfamily) [66-291]
- IPR000727: Target SNARE coiled-coil homology domain (domain) [231-324]
- IPR006012: Syntaxin/epimorphin, conserved site (conserved_site) [242-281]
- IPR006011: Syntaxin, N-terminal domain (domain) [62-223]
Interaction partners: - Synaptobrevin-B
- Synaptobrevin-A
- Alpha-soluble NSF attachment protein
- t-SNARE family protein
- Vesicle-fusing ATPase
- Protein transport protein sec1
- Vesicle-trafficking protein SEC22b
- Cysteine proteinase 4
- t-SNARE family protein
- Synaptobrevin domain-containing protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0042592 (homeostatic process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0051703 (biological process involved in intraspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0048878 (chemical homeostasis), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0051641 (cellular localization), GO:0019725 (cellular homeostasis), GO:0009607 (response to biotic stimulus), GO:0006885 (regulation of pH), GO:0099120 (socially cooperative development), GO:0071840 (cellular component organization or biogenesis), GO:0006950 (response to stress), GO:0140352 (export from cell), GO:0051707 (response to other organism), GO:0050801 (monoatomic ion homeostasis), GO:0055082 (intracellular chemical homeostasis), GO:0043207 (response to external biotic stimulus), GO:0031154 (culmination involved in sorocarp development), GO:0048837 (sorocarp sorus development), GO:0030154 (cell differentiation), GO:0009617 (response to bacterium), GO:0006952 (defense response), GO:0032940 (secretion by cell), GO:0016043 (cellular component organization), GO:0030641 (regulation of cellular pH), GO:0030587 (sorocarp development), GO:0098542 (defense response to other organism), GO:0006887 (exocytosis), GO:0055080 (monoatomic cation homeostasis), GO:0051453 (regulation of intracellular pH), GO:0042742 (defense response to bacterium), GO:0061024 (membrane organization), GO:0016192 (vesicle-mediated transport), GO:0006873 (intracellular monoatomic ion homeostasis), GO:0006996 (organelle organization), GO:0050829 (defense response to Gram-negative bacterium), GO:0006909 (phagocytosis), GO:0006897 (endocytosis), GO:0010324 (membrane invagination), GO:0051454 (intracellular pH elevation), GO:0016050 (vesicle organization), GO:0051452 (intracellular pH reduction), GO:0030003 (intracellular monoatomic cation homeostasis), GO:0099024 (plasma membrane invagination), GO:0006911 (phagocytosis, engulfment)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0030054 (cell junction), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0045202 (synapse), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0097708 (intracellular vesicle)