Protein: Peroxisome proliferator-activated receptor delta (A0A0G2JVK6)
Organism: Rattus norvegicus (Rat)
Function: Not known
Sequence: MEQPQEETPEAREEEKEEVATGDGAPELNGGPEHTLPSSSCTAIRFGRMPEAEKRKLVAGLTASEGCQQNPQLADLKAFSKHIYNAYLKNFNMTKKKARSILTGKSSHNAPFIIHDIETLWQAEKGLVWKQLVNGPPPYNEISVHVFYRCQSTTVETVRELTEFAKNIPNFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTHEFLRSIRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPQVEAIQDTILQALEFHLQVNHPDSQYLFPKLLQKMADLRQLVTEHAQMMQWLKKTESETLLHPLLQEIYKDMY
InterPro domains: - IPR035500: Nuclear hormone receptor-like domain superfamily (homologous_superfamily) [71-342]
- IPR003075: Peroxisome proliferator-activated receptor, beta (family) [120-289]
- IPR001723: Nuclear hormone receptor (family) [153-316]
- IPR000536: Nuclear hormone receptor, ligand-binding domain (domain) [112-340]
- IPR003074: Peroxisome proliferator-activated receptor (family) [65-335]
- IPR050234: Nuclear hormone receptor family NR1 subfamily (family) [43-339]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0008289 (lipid binding), GO:0038023 (signaling receptor activity), GO:0097159 (organic cyclic compound binding), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0008134 (transcription factor binding), GO:0003676 (nucleic acid binding), GO:0003707 (nuclear steroid receptor activity), GO:0005504 (fatty acid binding), GO:0005102 (signaling receptor binding), GO:0043177 (organic acid binding), GO:0043168 (anion binding), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific), GO:0036041 (long-chain fatty acid binding), GO:0140297 (DNA-binding transcription factor binding), GO:0003677 (DNA binding), GO:0001221 (transcription coregulator binding), GO:0031406 (carboxylic acid binding), GO:0033293 (monocarboxylic acid binding), GO:0043565 (sequence-specific DNA binding), GO:0001223 (transcription coactivator binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0051179 (localization), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0009628 (response to abiotic stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0032879 (regulation of localization), GO:0006807 (nitrogen compound metabolic process), GO:0051241 (negative regulation of multicellular organismal process), GO:0051239 (regulation of multicellular organismal process), GO:0071704 (organic substance metabolic process), GO:0003008 (system process), GO:0033036 (macromolecule localization), GO:0065008 (regulation of biological quality), GO:0050793 (regulation of developmental process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0023051 (regulation of signaling), GO:0006950 (response to stress), GO:0045926 (negative regulation of growth), GO:0051093 (negative regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0040008 (regulation of growth), GO:0044238 (primary metabolic process), GO:0007610 (behavior), GO:0048638 (regulation of developmental growth), GO:0001666 (response to hypoxia), GO:1901564 (organonitrogen compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0060341 (regulation of cellular localization), GO:0048731 (system development), GO:0070482 (response to oxygen levels), GO:0001558 (regulation of cell growth), GO:0048513 (animal organ development), GO:0044255 (cellular lipid metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0046620 (regulation of organ growth), GO:0008217 (regulation of blood pressure), GO:0010883 (regulation of lipid storage), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:2000026 (regulation of multicellular organismal development), GO:0006629 (lipid metabolic process), GO:0009888 (tissue development), GO:0006139 (nucleobase-containing compound metabolic process), GO:0060322 (head development), GO:0010646 (regulation of cell communication), GO:0045596 (negative regulation of cell differentiation), GO:0048640 (negative regulation of developmental growth), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0048640 (negative regulation of developmental growth), GO:0030308 (negative regulation of cell growth), GO:0009889 (regulation of biosynthetic process), GO:0062012 (regulation of small molecule metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0070727 (cellular macromolecule localization), GO:0045595 (regulation of cell differentiation), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0051128 (regulation of cellular component organization), GO:0014741 (negative regulation of muscle hypertrophy), GO:0035094 (response to nicotine), GO:0071456 (cellular response to hypoxia), GO:0050890 (cognition), GO:0010565 (regulation of cellular ketone metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0071453 (cellular response to oxygen levels), GO:0043436 (oxoacid metabolic process), GO:0048732 (gland development), GO:0061448 (connective tissue development), GO:0006638 (neutral lipid metabolic process), GO:0032880 (regulation of protein localization), GO:0051960 (regulation of nervous system development), GO:0072521 (purine-containing compound metabolic process), GO:0061008 (hepaticobiliary system development), GO:0010468 (regulation of gene expression), GO:0046890 (regulation of lipid biosynthetic process), GO:0007420 (brain development), GO:0055022 (negative regulation of cardiac muscle tissue growth), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0051254 (positive regulation of RNA metabolic process), GO:0060420 (regulation of heart growth), GO:0046486 (glycerolipid metabolic process), GO:0007399 (nervous system development), GO:0036293 (response to decreased oxygen levels), GO:0031326 (regulation of cellular biosynthetic process), GO:0072091 (regulation of stem cell proliferation), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0007417 (central nervous system development), GO:0014070 (response to organic cyclic compound), GO:0051252 (regulation of RNA metabolic process), GO:0019216 (regulation of lipid metabolic process), GO:0006937 (regulation of muscle contraction), GO:0016070 (RNA metabolic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0033865 (nucleoside bisphosphate metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0001889 (liver development), GO:0019395 (fatty acid oxidation), GO:0006163 (purine nucleotide metabolic process), GO:0097421 (liver regeneration), GO:0019217 (regulation of fatty acid metabolic process), GO:0006357 (regulation of transcription by RNA polymerase II), GO:0034504 (protein localization to nucleus), GO:0051170 (import into nucleus), GO:0032787 (monocarboxylic acid metabolic process), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0072329 (monocarboxylic acid catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)