wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Testis-specific protein Y-linked (Q6PFI8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MSTNSDSSQPSETNTRKRSASPSGECESTQLKQAKVSVEEQKNEPQEDAEPEKVGNGEPKDGAEPSEGAKEKEAKIEDEVAAQESTGQANVSGGESARQPSDSAAIAAAEALASLTGGDADDDCKEMPCSSKKASREKSRDKSNRPGCSQSDRRTEAAAADSSSSLLLCEDQEDPSFVDDDEEEEEDEDSLPGSSSTASSSVASDNEDNEDGECAIVSVKMAPEVRQSVALLAQVQMRLDALEKKGARLHQRLEMKLSRQRRPHLDQRSAITQAVPGFWVTALLNHPHLSAHIDETDEDALSYMTNLEIESFKNNKLGYRICFHFRRNPFFQNKMIVKELHLGMGGSPVSFSNPILWHRGQNLVGSGEPRRTSQGVYQSFFHWFSDHSNPGRDDIAQILREDLYRNPLRYYLTPLWEPRENGSSAPKPQGSSNRDECVIISDSDEDEEQNSQSLGQEDDEDDDQGGGSEENERDEGESSCEERDEEEVDVEEVEVSHDSGGCEAREQEEEDIDVDEEKS
InterPro domains: - IPR002164: Nucleosome assembly protein (NAP) (family) [207-446]
- IPR037231: NAP-like superfamily (homologous_superfamily) [221-412]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0002088 (lens development in camera-type eye), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0043010 (camera-type eye development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Kisspeptin (B6ZIV2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MNTRALILFMSAMVSQSTAMRAILTDMDTPEPMPDPKPRFLSMERRQFEEPSASDDASLCFFIQEKDETSQISCKHRLARSKFNYNPFGLRFGKRNEATTSDSDRLKHKHLLPMMLYLRKQLETS
Interaction partners: - KISS1 receptor b
- KiSS-1 metastasis suppressor
- Progonadoliberin
- KISS1 receptor a
- Progonadoliberin
- Lhb protein
- Follicle-stimulating hormone beta subunit
- FMRFamide related peptide 1
- Preprotachykinin 2a
- Golgi transport 1Bb
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0001664 (G protein-coupled receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0050793 (regulation of developmental process), GO:0071840 (cellular component organization or biogenesis), GO:0051239 (regulation of multicellular organismal process), GO:0003008 (system process), GO:0007610 (behavior), GO:0050794 (regulation of cellular process), GO:0050877 (nervous system process), GO:2000026 (regulation of multicellular organismal development), GO:0030278 (regulation of ossification), GO:0003013 (circulatory system process), GO:0007626 (locomotory behavior), GO:0070167 (regulation of biomineral tissue development), GO:0030500 (regulation of bone mineralization), GO:0006996 (organelle organization), GO:0008015 (blood circulation), GO:0007600 (sensory perception), GO:0007005 (mitochondrion organization), GO:0050954 (sensory perception of mechanical stimulus), GO:0007605 (sensory perception of sound)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Solute carrier organic anion transporter family member (A0A8M1NHT1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane; Multi-pass membrane protein
Sequence: MEGSTIGMEHSDRNQKTSQTKCCPPRLKIFIAALAFCYFSKSMTASYTKSTITQIERRFEIPSSTVGIIDGGFEMGNMLVITLVSYVGAKFHRPKIIGAGVLLMGIGTLLMASPHFIMGRYKYGTAATHTNDAGNFTVISTCSSDSQKTLQQPFSGCRKEEAESSPLWVIVVLGNTMLGIGEASIIPLGMSFVDDYARPENSAFYIGCLNTIKGIGPIFGFVLGSLCANLYVDIGLVNKESVTITPQDSRWVGAWWLGYVVSGLLTVLAAFPFWFLPKALPENSQISLLDNTPQQHKTTPSLTEIVKDFAPTFKRLLTNKIYILYLAYSIVAFNDFAILVTYTPKYLEQQFGQSASKANFLIGVTCVPAVALGVFLSGLMMKRFKWGLLASARVNLLTIVATVFLTVPFFALSCENLDIAGVTVPYQGSTEVQGVTSDVLPSCNADCGCPDLHWDPVCGENGVTYISPCHAGCSSTQGAGRNKTFHDCGCIQSWGLSVGNSSAVLGQCSQNPNCNRMMYLYLGLQSLALFVYSLGAVPLFTMSLRIVDPELKSLSVGVLLLSIRVLGGIPAPIYFGALVDSSCLKWGQRKSCGRGACRIYDIETFRFLFQGLTNCLRVLACSLLWIATIWIKRKIQNDKQISEDMELQRGPSDDPEHEDAVK
InterPro domains: - IPR002350: Kazal domain (domain) [437-492]
- IPR036259: MFS transporter superfamily (homologous_superfamily) [16-631]
- IPR036058: Kazal domain superfamily (homologous_superfamily) [438-490]
- IPR020846: Major facilitator superfamily domain (domain) [30-629]
- IPR004156: Organic anion transporter polypeptide (family) [15-644]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0005319 (lipid transporter activity), GO:0015125 (bile acid transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity), GO:0005342 (organic acid transmembrane transporter activity), GO:1901618 (organic hydroxy compound transmembrane transporter activity), GO:0046943 (carboxylic acid transmembrane transporter activity), GO:0008028 (monocarboxylic acid transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0009719 (response to endogenous stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:0015833 (peptide transport), GO:0042886 (amide transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Neuroserpin precursor (B3DJI9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Secreted
Sequence: MLLLVVLPPLLLLRGCFCQASDVPEDVTAEFSVRLYHQLQISSGEENIIFSPLSVALALGMVELGARGSSLQEIRQAVGYSHFREDEEFSLLRNLSQALSTDEEQYVVRLANSLFLQSGVHFNEDFLQLMKKYFRAEVETVDFSQSTAVAERINSWVLNHTESKIQNLVSAEDFSSSTMIMLVNAVYFRGSWKNQFRPENTRTFSFTRDDGSEVQTLMMYQQGDFYYGEFSDGTTEAGGVYQVLEMLYEGEDMSMMIVLPRQEVPLASLEPIIKAPLLEEWANNVKRQKVEVYLPRFKVEQKIDLRESLQQLGIRSIFSKDADLSAMTAQMTDGQDLFIGKAVQKAYLEVTEEGAEGAAGSGMIALTRTLVLYPQVMADHPFFFIIRNRKTGSILFMGRVMNPELIDPFDNNFDM
InterPro domains: - IPR036186: Serpin superfamily (homologous_superfamily) [8-403]
- IPR042178: Serpin superfamily, domain 1 (homologous_superfamily) [52-352]
- IPR042185: Serpin superfamily, domain 2 (homologous_superfamily) [45-403]
- IPR023796: Serpin domain (domain) [28-403]
- IPR023795: Serpin, conserved site (conserved_site) [376-386]
- IPR000215: Serpin family (family) [27-403]
Interaction partners: - Transmembrane and coiled-coil domain-containing protein 4 isoform X1
- Membrane-spanning 4-domains subfamily A member 4A
- Programmed cell death protein 10-A
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140678 (molecular function inhibitor activity), GO:0061134 (peptidase regulator activity), GO:0004857 (enzyme inhibitor activity), GO:0061135 (endopeptidase regulator activity), GO:0030414 (peptidase inhibitor activity), GO:0004866 (endopeptidase inhibitor activity), GO:0004867 (serine-type endopeptidase inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0035239 (tube morphogenesis), GO:0048514 (blood vessel morphogenesis), GO:0002040 (sprouting angiogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix)
Protein: Estrogen receptor 2b (A0A8M2B359)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
Sequence: MSSSPGPAPVLDSSKADRGASPALLPRLYASPLGMDNQTVCIPSPYVEACQDYSPPHGGEFNHGALTLYSPVSSAVLGFHRPPVSESLVPLSPTILWPPHSLHCPPPLAYSETRSHSAWEEAKTHTLSQSSSVLSHTKLLGQQLEGDNGLNPSASIVGKGDTHFCAVCHDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKSRRKSCQACRLRKCYEVGMMKCGMQLTLRFCVRRERCSYRGARHRRNPQIRDSSGGVVGLRGQSQQHLEFPLSPSQHLFPSGGRAEGRGLNYSPEQLVSCILEAEPPQIYLREPVKKPYTEASMMMSLTSLADKELVLMISWAKKIPGFVELTLSDQVHLLECCWLDILMLGLMWRSVDHPGKLIFTPDLKLNREEGNCVEGIMEIFDMLLATTSRFRELKLQREEYVCLKAMILLNSNNCSSLPQTPEDVESRGKVLNLLDSVTDALVWIISRTGLSSQQQSIRLAHLLMLLSHIRHLSNKGIEHLSNMKRKNVVLLYDLLLEMLDANTSQSSRMLEDRQQSPENLHTSRPQPDLKDSDQETPHSPRAEETVNKTLHSSLLREDMDTN
InterPro domains: - IPR001723: Nuclear hormone receptor (family) [226-516]
- IPR013088: Zinc finger, NHR/GATA-type (homologous_superfamily) [157-262]
- IPR028355: Estrogen receptor beta/gamma (family) [21-585]
- IPR021064: Estrogen receptor beta-like, N-terminal (domain) [31-132]
- IPR024178: Estrogen receptor/oestrogen-related receptor (family) [30-559]
- IPR050200: Nuclear hormone receptor family NR3 subfamily (family) [109-539]
- IPR000536: Nuclear hormone receptor, ligand-binding domain (domain) [304-540]
- IPR035500: Nuclear hormone receptor-like domain superfamily (homologous_superfamily) [299-548]
- IPR001628: Zinc finger, nuclear hormone receptor-type (domain) [162-237]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0060089 (molecular transducer activity), GO:0003700 (DNA-binding transcription factor activity), GO:0008289 (lipid binding), GO:0038023 (signaling receptor activity), GO:0097159 (organic cyclic compound binding), GO:0042562 (hormone binding), GO:0003707 (nuclear steroid receptor activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific), GO:0005496 (steroid binding), GO:0004879 (nuclear receptor activity), GO:0098531 (ligand-activated transcription factor activity), GO:1990239 (steroid hormone binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009719 (response to endogenous stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0043627 (response to estrogen)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Doublecortin domain-containing 2B (A0A8M6Z9L0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MASTGVTSHLPPVKSVMVYRNGDPFFSGRRFVVNQRQIATMDALLNDITLNIGAPLAVRTLYTPRYGHRVADLGDLQQGAQYVAAGSERFKKLDYLSAGLKKAVEPTQSKTLARPNVSAKWRKVITLPCIIHVFRNGDILSPAMRLIIPRHMLKNLEQILSLISEKAMLRTGAVRRICTLEGFTVTSAEELETGQCYVAVGSERFKKLPYVEILLNKATGSSADRHYAGDRGLHRRIEDTHSDSTLLNSPEREGRRVKSTGDDAERESSPQPVKRRGRRAEREGENSVFYARPVRVRRQQPVHRPTPKVITEPSVFKASESTMREEVRGAEEVTEDENTAVELPVDQREAEIVEDEELPEREFAASEIQTWDDTSAPQRETPQEHTPPHETNKYESESHHSRSSSSSSLRLSPRHEETQQEPIRRSHDEQTHRDADSPRQAAEDAQD
InterPro domains: - IPR036572: Doublecortin domain superfamily (homologous_superfamily) [6-216]
- IPR003533: Doublecortin domain (domain) [9-211]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0071840 (cellular component organization or biogenesis), GO:0032989 (cellular component morphogenesis), GO:0000902 (cell morphogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0016043 (cellular component organization), GO:0022008 (neurogenesis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0032990 (cell part morphogenesis), GO:0048813 (dendrite morphogenesis), GO:0048858 (cell projection morphogenesis), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0048812 (neuron projection morphogenesis), GO:0061564 (axon development), GO:0007409 (axonogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0042995 (cell projection), GO:0043227 (membrane-bounded organelle), GO:0120025 (plasma membrane bounded cell projection), GO:0005929 (cilium), GO:0031514 (motile cilium)
Protein: Ribose-phosphate pyrophosphokinase 1 (Q7ZW39)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis
Sequence: MPNIKIFSGSSHPDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIKENINEWKNCTIVSPDAGGAKRVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTVCHAADKLVSAGAIKVYAILTHGIFSGPAISRINNANFEAVVVTNTIPQEDKIKHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL
InterPro domains: - IPR000842: Phosphoribosyl pyrophosphate synthetase, conserved site (conserved_site) [128-143]
- IPR029099: Ribose-phosphate pyrophosphokinase, N-terminal domain (domain) [4-120]
- IPR037515: Ribose-phosphate pyrophosphokinase, bacterial-type (family) [4-314]
- IPR029057: Phosphoribosyltransferase-like (homologous_superfamily) [6-306]
- IPR000836: Phosphoribosyltransferase domain (domain) [147-274]
- IPR005946: Ribose-phosphate pyrophosphokinase (family) [1-316]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016778 (diphosphotransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0072359 (circulatory system development), GO:0007507 (heart development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: PHD finger protein 21A isoform X7 (A0A8M9PN25)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
Sequence: MMELQTLQEALKVEIQVHQKLVAQMKQDPQNADLKKQLHELQAKITALSEKQKKVVEQLRKELLVKQEPDLKPQTFAATTDGKTVLLTAACPASQPISGPPHNQGAPQKTLTVTPVITAKTLPLVLKAATSTMPASMATQRSAVAMVTAINNPTRPGANSDSQSTPINLQMASKLPNQDTDAGTRIVSKNVIVVQATTTSAQPIKVPQFVPPPRLTPRPTFQPQVRPKPPTPINVPIAPAPPPPMVAAPLIQRPLMLTTKLTSSLPASAGPIHQVRIVNGQQCTTIDKTTTTVTGTTQLAGIVISPAQTLQISNLNSDLKTVKPQGGPEQVVIKTPPSSSPPLPPPPAKVKREESPQKLAFMVSLGLVTHDHLEEIQSRRQERKRRTTANPVYSGAVFEPERKKSAVTYLNTPLHQGTRKRGRPPKYSTTTTTTTSSSTAVPELGCNPLLSPTSSLPASPAPERPDTGGFPLSVHPHSVPQPSPSSGDGDIHEDFCTVCRRSGQLLMCDTCSRVYHLDCLDPPLKNIPKGMWICPKCQDQILKKEEAIPWPGTLAIVHSYIAYKEAKEEEKQKLMKWSAELKLEREQLEQRVKQLSNSITKCMETKNSILARQKDMQASLEKVKHLVRLIQSFNFTQPMETETLKDSKQDCAESGSIKDSKDTTQVCVQESPTEPSVQVPAAVAVPEVKAEPEVGEMAEPAAAVTPEAVSGESGVSVLEVPKTTVDEDMMDTAKTVEPVESPQVRDVKTNGGTDCVCTGLNPEEESTVDAVDSENIPPIDSSCAEDAGKMEVELQEDGSHGMNTNNGKTSEPSQQALPAPLSSVDNPK
InterPro domains: - IPR011011: Zinc finger, FYVE/PHD-type (homologous_superfamily) [482-550]
- IPR019786: Zinc finger, PHD-type, conserved site (conserved_site) [496-537]
- IPR001965: Zinc finger, PHD-type (domain) [495-538]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [485-540]
- IPR019787: Zinc finger, PHD-finger (domain) [493-540]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0048856 (anatomical structure development), GO:0060324 (face development), GO:0060322 (head development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Kinesin-like protein KIF14 (Q1LW14)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, cytoskeleton, spindle. Midbody. Nucleus
Sequence: MSSSTPHGGRRVEGHTPAEGLSKMSELQTQELKMENSAVTVAVRVRPFSSREKIEKACQVIFMENQDTLVQHPDTKQTHKFTFDFSFCSINEADASFSSQQLIYEKLARPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFGEETGVIPRFCEELFSRLARSETKEMSCHLEMSYFEVYNEKIHDLLVAKDEQNQKKMPLRVREHPVYGPYVADLSTNVVSSYSDIKTWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEEEEHDHCITSRINLVDLAGSERCTSAQTSGDRLREGASINKSLLTLGKVISSLSEQSQSRKKVFTPYRESVLTWLLKESLGGNSKTAMIATLSPAASNMEESLSTLRYAQQARMIINIAKVNEDTNAKLIRDLKAEVEKLRAAQMSSQGVEPEKMRLFQQEIAALKNKLCQQEHEMAEAHRTWKEKLEEAERRKREEAKELQRAGVTFKVDNRLPNLVNLNEDPQLSEMLLYMIKEGQTKVGKLKSESAHDIQLSGALIADQHCVISSVKGTVSIKPMPNAKTFVNGHLVSECTVLHHGDRVILGGDHYFRFNHPAEVQSGKRASCWSSGDGHKDFEFAKNELLSAQRAQLEAEIQEARLKAKEEMMQGIQVAKEMAQKELSEQKSLYEIKIRALERELKEESERKREQELHKQRAASQIEQLQSVKTLLEKEVSSHKRRLQMEAQATRQAMADHDVRHAKIVAALEAEKRKIAEDLAQIEMKRALKVTQTPKMAIPQWDAMKLSLMIEEANKISGKLRKHTVFSRHEAADKEVEGGDAQLQVQVQNTKLGISTFWSLEKFQSNLAAMREIEQGESASKDDDVFYDPNDEWEPDLSASSSTSSFSRRRSRSLLKSRRISGRLYEIRVHPIQSLHCTPSQSTGLMNKPPSLHSSTSDSALPGICKDLIGSAVARLRSCQSADESESLADKLTLDLLSVHRAVRAITDLYEDLDDDSEENLFACSTEAQTHLVKATSAVERAVFITMHWVSSITFGSITVSQRAEELKMEVKKIGGYLQLLIQGCDSEISSMVTEARKRVAECMNAVFKTIGFLAAVNGTDLHLNEQNSEIIDNRSIVDCLQDGMRQSVKDLLSVGLLVTEEMLQVSHTGSTISKWMDVARSLQNYLRCCLSKSSDSSENHCVDYESSNLYDIQSTTTKLLKLNQAIKDLHSSLSRFLKGRRSDTSLSEAIQSSSQTIDKIISSLPHEITGRSDGLQLQDDVQSALQALLAVFSNSTDEIQKPTTDRHFVQSGYSSRNRTVPKVVYSLSSGISTCSRDARWV
InterPro domains: - IPR036961: Kinesin motor domain superfamily (homologous_superfamily) [37-406]
- IPR008984: SMAD/FHA domain superfamily (homologous_superfamily) [478-582]
- IPR032405: Kinesin-associated (domain) [434-504]
- IPR000253: Forkhead-associated (FHA) domain (domain) [505-572]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [37-391]
- IPR056523: KIF14, four-helical bundle (domain) [951-1092]
- IPR019821: Kinesin motor domain, conserved site (conserved_site) [277-288]
- IPR001752: Kinesin motor domain (domain) [36-390]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019904 (protein domain specific binding), GO:0030165 (PDZ domain binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009887 (animal organ morphogenesis), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0048854 (brain morphogenesis), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: stearoyl-CoA 9-desaturase (F1QG70)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein
Sequence: MPDSDVKAPVLQPQLEAMEDEFDPLYKEKPGPKPPMKIVWRNVILMSLLHIAAVYGLFLIPSAHPLTLLWAFACFVYGGLGITAGVHRLWSHRSYKATLPLRIFLAIGNSMAFQNDIYEWSRDHRVHHKYSETDADPHNSNRGFFFSHVGWLLVRKHPEVIERGRKLELTDLKADKVVMFQRRFYKLSVVLMCFVVPTVVPCYMWGESLWIAYFIPTLLRYALGLNSTWLVNSAAHMWGNRPYDGNIGPRENRFVTFSAIGEGYHNYHHTFPYDYSTSEYGWKLNLTTIFVDTMCFLGLASNRKRVSKELILARVKRTGDGSYRSG
InterPro domains: - IPR001522: Fatty acid desaturase type 1, conserved site (conserved_site) [261-275]
- IPR005804: Fatty acid desaturase domain (domain) [68-273]
- IPR015876: Acyl-CoA desaturase (family) [27-322]
Interaction partners: - stearoyl-CoA 9-desaturase
- Fatty acid synthase
- Cytochrome b5 reductase 4
- acetyl-CoA carboxylase
- Acyl-CoA 6-desaturase
- Very long chain fatty acid elongase 6
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen), GO:0016717 (oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water), GO:0016215 (acyl-CoA desaturase activity), GO:0004768 (stearoyl-CoA 9-desaturase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:1901700 (response to oxygen-containing compound), GO:0070542 (response to fatty acid), GO:0033993 (response to lipid)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0031090 (organelle membrane), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098827 (endoplasmic reticulum subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0005789 (endoplasmic reticulum membrane)