Protein: Dynactin 150 kDa subunit (Q54VD6)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Not known
Subcellular location: Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}.
Sequence: MSEEGKSLPPGTRVSINGKPELGLGTVKYCGMTKFSPGRWVGIELDSAAGKNDGTVQGERYFDCKPAHGLFVKPNMAVIVEEQPQTQTQPQPQQTSNIDDGIDDSKLMPAPITTPSKIAATSGIRPPSSTGIRPPSSLGKGRPSLTGSSSTTSSSSSSSSTTTTTTTPTSSIKKPSESGIRRPSTIPSSTTTTTSTTSTSPTSTSPLTSPPPEKKSEPSPPTTTTISPPPPTVVEPTPIEQPQPTPSKISRPPSSASSRPTGIPKPSGLKEPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPTPIITPNPTITTTTTPIPTPSTPLPPSTSNSITLTPPSTQKKQSKIIQGEDEEEEEEINDLLNKSLATERMNQAVQENIDKMMTTINDLKEDKNRSQEEINSLKDRLKEAVASKDKQIKENEKQIKENEKQIQQLEKTIAIKEKENENLLKTQHRNEDKEKSEFEKEKQSLLEQISNLNENLELLTLDKEVTEEKLEMTELEFEQVKEELEMMRIEYDSLKIQLDEKPTRSIDESLPTDVLVLQEQNDKLKEALVKLRDITMNDKHELSKKTKELETLSKQVQSLTEKSNKLEMELSIKIEETLELKLALEDAEVSESLITDLTDKNLSLNEELEELKVSIADLESFRDLSEELSENQVALEKSLRLEVNSKDIEILNIQSQMTNLQIKNQENEKTILQFRDLVGRLQHKLEEMRRKEEEQSEHQHSWSAIQQQLLSKNIQLQNQMIKATALEIDHQLEQSKSVESQVHLAFVYEYLPEQTFQLDNDAIKMLLLLKRIILKSELAQKYLNRTYKVEEIGNKVAGGDSDQMLLTSGQVAHSLSIIHILEHLAISTTWLTETLERSSSDQWLRSGRSIKDMLNQERILDNLLQLIKLEQFGSSYSSTDLEKLCQRIDSILTNIFGNITNSTNDSGSNNTSSNNNNNNNVDQIFKPEWSILLNYILGIQYNIKQIMLNDINITTTITHNDQFIFPHKEMSKVLSVCRKVVKNLLTKPYLSQSSIVRDLLKTSEHTCKSILLELVQSLPKIQDESINSGGGGSGSGSGNLNNNLNDLLIKIQARSDLIISNSNSLNKNNDEFSNDDYQDQEESKLSSSLEKVFYRMNVQLSDVVETIIAGDLNLSEKDKQALTKQSPWAERANQLKQSLGEVGQLRDIIQSKDAELLENLKTIKAKEAELIEEKRKEESFDKRIRILQKSENEVTEKLAKEIKSREDNEKNFRQALNLLRNEKNSLEHDSKNMQNKILALQQELQKKLNTPLSPMIANQELLRSVDDINVLSLKKAIRFLRNENLKLKSQKSIKELCELNLIQNYRHQQQIKQQQQQQSNNSSTSSTSSSTPTLLEQQAKKQQIKFNEIVEYSKQVNHMMSSILESTATPKVLDLSNKSISSSSSSSSSSNDRTSANEIEKQKLLIKQQERKVKQLQSKMTNFISSSTCQFGLNNYADANQSRMLKESIPLKIANITIPNLNINNINNNNNNTNSLMLDKDIQEALNSKTLSIQLFTNPQTFKEIHQVFVK
InterPro domains: - IPR036859: CAP Gly-rich domain superfamily (homologous_superfamily) [1-101]
- IPR022157: Dynein associated protein (domain) [709-927]
- IPR000938: CAP Gly-rich domain (domain) [11-78]
Interaction partners: - Dynactin subunit 2
- Dynactin subunit 4
- Dynein heavy chain, cytoplasmic
- Cytoplasmic dynein 1 intermediate chain
- Dynactin subunit 5
- Dynactin subunit 6
- Cytoplasmic dynein 1 light intermediate chain 1
- F-actin-capping protein subunit beta
- F-actin-capping protein subunit alpha
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0015631 (tubulin binding), GO:0008017 (microtubule binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0009987 (cellular process), GO:0051641 (cellular localization), GO:0022402 (cell cycle process), GO:0007049 (cell cycle), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0007017 (microtubule-based process), GO:0051640 (organelle localization), GO:0007059 (chromosome segregation), GO:1903047 (mitotic cell cycle process), GO:0051656 (establishment of organelle localization), GO:0007051 (spindle organization), GO:0050000 (chromosome localization), GO:0051649 (establishment of localization in cell), GO:0016043 (cellular component organization), GO:0000226 (microtubule cytoskeleton organization), GO:0000278 (mitotic cell cycle), GO:1902850 (microtubule cytoskeleton organization involved in mitosis), GO:0098813 (nuclear chromosome segregation), GO:0140014 (mitotic nuclear division), GO:0007080 (mitotic metaphase plate congression), GO:0007052 (mitotic spindle organization), GO:0006996 (organelle organization), GO:0000070 (mitotic sister chromatid segregation), GO:0051303 (establishment of chromosome localization), GO:0007010 (cytoskeleton organization), GO:0051310 (metaphase plate congression), GO:0000819 (sister chromatid segregation), GO:0048285 (organelle fission), GO:0051276 (chromosome organization), GO:0000280 (nuclear division)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0005813 (centrosome), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015630 (microtubule cytoskeleton)