Protein: Host cell factor 1 (A0A8M9PQY4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm. Nucleus
Sequence: MASSGTSVLQPRWKRVLGWSGPVPRPRHGHRAVAIKELMVVFGGGNEGIVDELHVYNTATNQWFIPAVRGDIPPGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEWKRLKPKAPKNGPPPCPRLGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYTLELRPGSNVAGWDIPITYGVLPPPRESHTAVVYTEKTSKKSRLIIYGGMSGCRLGDLWTLDIDTLTWNKPAISGAAPLPRSLHSATTITNKMFVFGGWVPLVMDDVKVATHEKEWKCTNTLACLNLDSMSWETILMDTLEDNIPRARAGHCSVAINNRLYVWSGRDGYRKAWNNQVCCKDLWYLETDRPQPPSRVQLVRANTNSLEVSWGAVPTADTYLLQLQKYDIPAATAATSPTVNPMPSVPVNSPKSPVPAAAAPAAQSMPLSGVTLVPQVPSPTTAMPTSPLAASPRGPAILKVAAPHSTPGTSVVTVRQATPGAKSPVTVTSLPAGVRMVVPAQSTQGTPIGSSPQMSGMAALAAAAAATQKIPPSSATTVLNVPAGATLVKTVAVTPGSTTLPATVKVASPVMVTNPATRMLKTAAAQVGTSAISTPNTPTRPIITVHKSGTVTVAQQAQVVTTMVGGVTKTITLVKSPITMGGSGALYSQLSSLGKVMSVVQTKPVQTSAVTGQAGSSPVTLIQTKTPLPAGTILKLVTSADGKPTTIITTSQAGGTGTKPTILGISSVSPTTTNKPGTTIIKTIPMSALQGATGVTSSAGIKSPITIITTKVVTPGTGTPGKIITAVPKLTGAGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVSPGTVSADKPTVTTLVVKGTTGVTTLGTVTGTVSTSVAGANVANASLATPVTTLASIATLSSQVINPTAITVSAAQTNLATATIQSASQPTQVTLITTPSGAEAQPGQDLPVSFLASPTSEQPSTTGADAGDSAGDGATTVTLVCSNPPCETHETGTTNTATTASAKIGTEQICSNPPCETHVTGTTNTSTTASANMGRAQQVCTNPPSETHDTGTTNTATTASCNMGSTEMGTVNSKPGSSSPPASSSSEPSTPVSESGAEAGVMRPENLRTGTTYTSTTARSNMGSDQTGTVQSSNKSQAAISSTMMPVSSSESPGDTDTSDVSGSVCSNPPCETRETGTTSTPTQSSADMESGQSGSVQRVCSNPPCETHETGTTNTSTQASSSMAAGQSGTAQRVCSNPPCETHETGTTNTPTQASSSLGAGQSGTVQRVCSNPPCETHETGTTNTPTQASSSLGAGQSGTVQRVCSNPPCETHETGTTNTQTQASSTLGAGQSGAVQRVCSNPRETHETGTTNTPTQASSGIGAGQNGTVQMVCSNPPCETHETGTTNTATTATSNLETGEGAAQQAGDGQSESATSTEPTSSTEPANPATQSRAITTVTQATPTPGPSVPEISSMAGSAVVSETPGEAEAMEQASAEAVAAGEEPMQTESQGELSEEGAVRVVAIDESAAGDGSTVLQVHVAMEAQPGQGDQAEQMEAGVEAAEAMSLAAQDSEALALPQELMSAEGQQTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVLSGEGDAGHDGQQATTIPIVLTQQELAALVQQQQQLQEAQAAAAQQLSAEAAAAALPTEGLAPADSLNDPASESNGHEMPTAVTGAVVRLLPRTSAETLAPSSTFAPSQPLVVASPAKMQAATALAEVANGIESAAGKQEAPPVVVKPPVKKENQWFDVGIVKVTNMVVTHYYVPADDSAVTDDDSGAIPDYSRMKKIELSPGTAYKFRVAGINACGRGTFSEVSAFKTCLPGFPGAPCAIKISKSPDGAHLTWEPPSVTSGKIIEYSVYLAIQSSQTVEAKASAPAQLAFMRVYCGPNPSCLVQSSSLSNAHIDYTTKPAIIFRIAARNEKGYGPATQVRWLQETSKDGSAAKPAAKRPVSSPDMKGAGPKKARSDQ
InterPro domains: - IPR059124: Host cell factor, Kelch-repeats domain (domain) [10-354]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [1780-1958]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [1764-1975]
- IPR003961: Fibronectin type III (domain) [358-1964]
- IPR015915: Kelch-type beta-propeller (homologous_superfamily) [6-395]
- IPR043536: Host cell factor (family) [7-1073]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003712 (transcription coregulator activity), GO:0003713 (transcription coactivator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0042592 (homeostatic process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0021700 (developmental maturation), GO:0048871 (multicellular organismal-level homeostasis), GO:0002262 (myeloid cell homeostasis), GO:0034101 (erythrocyte homeostasis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048469 (cell maturation), GO:0071695 (anatomical structure maturation), GO:0048872 (homeostasis of number of cells), GO:0043249 (erythrocyte maturation), GO:0030097 (hemopoiesis), GO:0030218 (erythrocyte differentiation), GO:0030099 (myeloid cell differentiation), GO:0061515 (myeloid cell development), GO:0048821 (erythrocyte development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)