Protein: Cardiac titin adult N2BA isoform (Q5VJM7)
Organism: Rattus norvegicus (Rat)
Sequence: YKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLEMKPPDIPDSRVPIPTMPIRAVPPEEIPPAVAPSIPLLLPLPEEKKPPAKRIEVTKKGVKKDTKKVVAKPKEEAPPPPPVPEVAKKPPPPTPMIPAKPSEIIDVSSKAEEVKITTITRKKEIHKEKEAVYERKEAVYEKKVLIEPWEEPYEELETEPYTEPYEEPYYEEPDEDYEEIKVEAKKEVHEEWEEDYEEGQEYYEREEGYDEGEEEWEEIYHEREIIQVQKEVHEDLHEKKIPAKVPEKKVPPPKVPEAPKKPAPEEKTAVPVAKKKEAPPPKVPEVPKKPVPEEKAPVPVPKKVEPPPAKVPEVPKKPVPEKKVPAPTPKKVEAPPAKVPEVPPKEVTPEKKVPVVPPKKPEAPPPKVPTAEKKVRKLLPEPKPQPKEEVVLKSVLRKRPEEEEPKVEPKKVEKVKKPEEPPPPPKAVEVEAPPEPKPKERKVPEPTKVPEIKPAIPLPGPEPKPKPEPEVKTMKAPPIEPAPTPIAAPVTAPVVGKKAEAKPKDEAAKPKGPIKGVAKKTPSPIEAERKKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIVLTE
InterPro domains: - IPR013783: Immunoglobulin-like fold (homologous_superfamily) [1-67]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [1-57]
- IPR004168: PPAK motif (repeat) [340-394]
- IPR013098: Immunoglobulin I-set (domain) [2-55]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0042221 (response to chemical), GO:0032879 (regulation of localization), GO:0071840 (cellular component organization or biogenesis), GO:0051050 (positive regulation of transport), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0048523 (negative regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:1903530 (regulation of secretion by cell), GO:1903829 (positive regulation of protein localization), GO:0051049 (regulation of transport), GO:0051047 (positive regulation of secretion), GO:0044085 (cellular component biogenesis), GO:0060548 (negative regulation of cell death), GO:0060341 (regulation of cellular localization), GO:0071495 (cellular response to endogenous stimulus), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0010035 (response to inorganic substance), GO:0010941 (regulation of cell death), GO:1901698 (response to nitrogen compound), GO:0070887 (cellular response to chemical stimulus), GO:0016043 (cellular component organization), GO:0051222 (positive regulation of protein transport), GO:1902074 (response to salt), GO:0010038 (response to metal ion), GO:0071417 (cellular response to organonitrogen compound), GO:1901652 (response to peptide), GO:0009743 (response to carbohydrate), GO:0034097 (response to cytokine), GO:1901215 (negative regulation of neuron death), GO:1901654 (response to ketone), GO:0043069 (negative regulation of programmed cell death), GO:0071310 (cellular response to organic substance), GO:0043067 (regulation of programmed cell death), GO:1904951 (positive regulation of establishment of protein localization), GO:0070201 (regulation of establishment of protein localization), GO:1902075 (cellular response to salt), GO:0002793 (positive regulation of peptide secretion), GO:1901699 (cellular response to nitrogen compound), GO:1901214 (regulation of neuron death), GO:0032880 (regulation of protein localization), GO:0050714 (positive regulation of protein secretion), GO:0022607 (cellular component assembly), GO:0051592 (response to calcium ion), GO:0051223 (regulation of protein transport), GO:0010243 (response to organonitrogen compound), GO:0071241 (cellular response to inorganic substance), GO:0051046 (regulation of secretion), GO:0090277 (positive regulation of peptide hormone secretion), GO:0014070 (response to organic cyclic compound), GO:0050708 (regulation of protein secretion), GO:1901701 (cellular response to oxygen-containing compound), GO:0070925 (organelle assembly), GO:0042981 (regulation of apoptotic process), GO:0043279 (response to alkaloid), GO:0071277 (cellular response to calcium ion), GO:0071392 (cellular response to estradiol stimulus), GO:0043066 (negative regulation of apoptotic process), GO:0033157 (regulation of intracellular protein transport), GO:0034284 (response to monosaccharide), GO:0071407 (cellular response to organic cyclic compound), GO:0071345 (cellular response to cytokine stimulus), GO:0071396 (cellular response to lipid), GO:0071248 (cellular response to metal ion), GO:0071312 (cellular response to alkaloid), GO:0043524 (negative regulation of neuron apoptotic process), GO:0042307 (positive regulation of protein import into nucleus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030017 (sarcomere), GO:0031674 (I band), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043292 (contractile fiber), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0030016 (myofibril), GO:0043232 (intracellular non-membrane-bounded organelle)