wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Cell wall adhesin EAP1 (G1UBC2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Cell wall protein which mediates cell-cell and cell-substrate adhesion. Required for biofilm formation and plays a role in virulence
Subcellular location: Secreted, cell wall. Membrane; Lipid-anchor, GPI-anchor
Sequence: MKVSQILPLAGAISVASGFWIPDFSNKQNSNSYPGQYKGKGGYQDDCGDDYKKGYKSKTYSKVKPITSTDCTTPIQPTGTTTGYTKDVVESTSYTTDTAYTTTVITVTKCDGGSCSHTAVTTGVTIITVTTNDVITEYTTYCPLTSTPATESTPATESTPATESTPATESTPATESTPATESTPCTTSTETTPATESTPATESTPATESTPATESTPATESTPATESTPATESTPATESTPCTTSTETTPATESTASTETASSTPVESTVIVPSTTVITVSSCYEDKCSVSSVTTGVVTISSEETIYTTYCPITSSITIPVPNTSTPAAPGTPVESQPVIPGTETTPAAPGTPVESQPVIPGTETTPAAPGTPVESQPATTPVAPGTETTPAAPGTPVESQPATTPVAPGTETTPAAPGTPVESQPVIPGTETTPAAPGTPVESQPATTPVAPGTETTPAAPGTPVESQPVIPGTETTPAAPGTPVESQPATTPVAPGTETTPAAPGTPVESQPVIPGTETTPAAPGTPGTEATPVTTQPVSVLSTSQVVTASGEFSTVTAHSTSIVASCPEGGCVPEGQQTETSPSVPTNGPEVEASSSVLSIPVSSVTTSTIASSSETSVPPAQVSTFEGSGSALKKPYYGLAVAALVYFM
InterPro domains: - IPR025928: Flocculin type 3 repeat (repeat) [102-314]
Interaction partners: - Agglutinin-like protein 3
- Agglutinin-like protein 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0071554 (cell wall organization or biogenesis), GO:0071555 (cell wall organization), GO:0016043 (cellular component organization), GO:0071852 (fungal-type cell wall organization or biogenesis), GO:0045229 (external encapsulating structure organization), GO:0031505 (fungal-type cell wall organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0009986 (cell surface), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005576 (extracellular region), GO:0043230 (extracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005618 (cell wall), GO:0065010 (extracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0009277 (fungal-type cell wall), GO:0030446 (hyphal cell wall), GO:1903561 (extracellular vesicle), GO:0030445 (yeast-form cell wall)
Protein: Probable circularly permuted 1,3-beta-glucanase PGA52 (Q59L72)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Probable circularly permuted 1,3-beta-glucanase involved in cell wall modification through beta-1,3-glucan network alterations such as increased branching or remodeling
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor
Sequence: MLFSSLLVSTLVSVATAANQEVEAIQFSNLGFSGTYNQVEKLSNIYKDSCSCEVNKTPVSFSGTNAPLNEEVSVHFRGPLVLNKFASYVSDGFKYGDDSSGDWKRLSYYEGSSGTSENVTFLTSAGKNSSCLGIGLTYAGTDGISKADSSTVLAKNTLINSNDEFVIFSNISCGKSGYNNDCGVYRSDIPAYHGFYGTTKMFLFEFQMPNETHTSTDISNYNMPAIWLLNAHIPRTAQYSMNVNCSCWRSGCGEFDIFEVMNSTEYLHMYSTIHDYQGSDDIQTGMAAPAYIERDLTGTMSGGVAFDSSGNAVVWVSNSTSFDSTIQASSVNSWVKQAGADVATTLATVTGQSATTTSKKSGGVSYQPSFITNLLMTVLTLWVI
InterPro domains: - IPR018807: Cell wall protein YJL171C/Tos1, N-terminal (domain) [24-89]
- IPR018805: Cell wall protein YJL171C/Tos1, C-terminal (domain) [101-334]
Interaction partners: - Hyphally regulated cell wall protein 3
- Predicted GPI-anchored protein 26
- Cell wall protein IFF4
- GPI-anchored hemophore PGA7
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0030246 (carbohydrate binding), GO:0016787 (hydrolase activity), GO:0030247 (polysaccharide binding), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009056 (catabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901575 (organic substance catabolic process), GO:0043170 (macromolecule metabolic process), GO:0005975 (carbohydrate metabolic process), GO:0016052 (carbohydrate catabolic process), GO:0009057 (macromolecule catabolic process), GO:0005976 (polysaccharide metabolic process), GO:0000272 (polysaccharide catabolic process), GO:0044042 (glucan metabolic process), GO:0009251 (glucan catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009986 (cell surface), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005576 (extracellular region), GO:0005618 (cell wall), GO:0009277 (fungal-type cell wall), GO:0030446 (hyphal cell wall)
Protein: GPI-specific phospholipase A2-like PGAP3 (A8WFS8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Involved in the fatty acid remodeling steps of GPI-anchor maturation where the unsaturated acyl chain at sn-2 of inositol phosphate is replaced by a saturated stearoyl chain. May catalyze the first step of the fatty acid remodeling, by removing the unsaturated acyl chain at sn-2 of inositol phosphate, generating a lyso-GPI intermediate. The fatty acid remodeling steps is critical for the integration of GPI-APs into lipid rafts
Subcellular location: Golgi apparatus membrane; Multi-pass membrane protein
Sequence: MFLAAAAFLLSAPASASQGDKEPVYRDCVKHCVRANCTGARLRGFQSTQPPYMALTGWTCRDDCRYQCMWTTVGLYQAEGYSIPQFHGKWPFARFLCFEEPASALASLLNGLACLLMLLRYRSAVPCQSPMYHTITAFSLVSLNAWFWSTVFHTRDTYLTEKMDYFCASAVILYSIYLCCVRTLGLRRPAISSMVGVLLILAFTSHVSYLTFVSFDYGYNMAANASIGIINLLWWLCWCWLNRRILPYWWRCGMVVLLLHGLALLELLDFPPLFWVLDAHAVWHLSTVPVHFLFYSFLIDDSLHLLNTEKPGVKLD
InterPro domains: - IPR007217: Per1-like (family) [3-304]
Interaction partners: - Acyltransferase PGAP2
- Metallophosphoesterase 1
- Phosphatidylinositol-glycan biosynthesis class W protein
- GPI alpha-1,4-mannosyltransferase I, catalytic subunit
- GPI-anchor transamidase
- GPI ethanolamine phosphate transferase 3
- ATPase family gene 2 protein homolog B
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit H
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q isoform X1
- GPI ethanolamine phosphate transferase 2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0035239 (tube morphogenesis), GO:0048514 (blood vessel morphogenesis), GO:0002040 (sprouting angiogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)
Protein: pH-responsive protein 1 (P43076)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Required for apical cell growth and plays an essential role in morphogenesis. May be integral to the pathogenic ability of the organism
Subcellular location: Cell membrane; Lipid-anchor, GPI- anchor
Sequence: MYSLIKSLATFATLFSLTLAKFESSTPPVEVVGNKFYFSNNGSQFLIRGIAYQQDAAGSVSSGYDADPNRKYNDPLADADACKRDVKYFKESNTNTLRVYAIDPDKDHEECMKIFSDAGIYIVADLSEPTVSINRNNPEWNLDLYKRYTKVIDKMQEYSNVLGFFAGNEVTNNRSNTDASAFVKAAIRDMKKYIKESDYRQIPVGYSSNDDEEIRVAIADYFSCGSLDDRADFFGINMYEWCGKSTFETSGYKDRTEEIKNLTIPAFFSEYGCNANRPRLFQEIGTLYSDKMTDVWSGGIVYMYFEEANKYGLVSVDGNSVKTLSDYNNYKSEMNKISPSLAHTSTLSSSDASKTLQCPGTAASTWKAATNLPPTPDESYCDCISKSLECVVADDVDKEDYGDLFGQVCGYIDCSAISADGSKGEYGVASFCSDKDRLSYVLNQYYLDQDKKSSACDFKGSASINSKASASGSCKAVSGVATGKASSSGGSSKSGSSSASASGSSSSSTSSGSSSSSGVKATQQMSMVKLVSIITIVTAFVGGMSVVF
InterPro domains: - IPR004886: Glucanosyltransferase (family) [6-539]
- IPR017853: Glycoside hydrolase superfamily (homologous_superfamily) [79-315]
- IPR012946: X8 domain (domain) [388-476]
Interaction partners: - Glucan 1,3-beta-glucosidase BGL2
- Hyphal wall protein 1
- Crh-like protein CRH11
- Cell wall protein RBT1
- pH-response transcription factor pacC/RIM101
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0071554 (cell wall organization or biogenesis), GO:0071555 (cell wall organization), GO:0016043 (cellular component organization), GO:0071852 (fungal-type cell wall organization or biogenesis), GO:0045229 (external encapsulating structure organization), GO:0031505 (fungal-type cell wall organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0016020 (membrane), GO:0009986 (cell surface), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005576 (extracellular region), GO:0043230 (extracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005618 (cell wall), GO:0005886 (plasma membrane), GO:0065010 (extracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0009277 (fungal-type cell wall), GO:0030446 (hyphal cell wall), GO:1903561 (extracellular vesicle), GO:0030445 (yeast-form cell wall)
Protein: Packaging protein 1 (P03271)
Organism: Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)
Function: Component of the packaging machinery which encapsidates the viral DNA into preformed capsids and transcriptional activator of the viral major late promoter (MLP). Binds, along with packaging proteins 2 and 3, to the specific packaging sequence on the left end of viral genomic DNA and displays ATPase activity thereby providing the power stroke of the packaging machinery. The activity of packaging protein IVa2 is stimulated by protein 33K which acts as a terminase. May be the protein that pumps DNA into the capsid powered by ATP hydrolysis. Specifically binds to the 5'-CG-3' nucleotides of the repeats making up the packaging sequence. Component of the DEF-A and DEF-B transcription factors that bind downstream elements of the major late promoter (MLP), and stimulate transcription from the MLP after initiation of viral DNA replication. DEF-A is a heterodimer packaging proteins 1 and 2 and DEF- B is a homodimer of packaging protein 1
Subcellular location: Virion. Host nucleus, host nucleoplasm. Host nucleus, host nucleolus. Note=Located at a unique vertex of the capsid. Present in about 6-8 copies per virion
Sequence: METRGRRPAALQHQQDQPQAHPGQRAARSAPLHRDPDYADEDPAPVERHDPGPSGRAPTTAVQRKPPQPAKRGDMLDRDAVEQVTELWDRLELLGQTLKSMPTADGLKPLKNFASLQELLSLGGERLLADLVRENMRVRDMLNEVAPLLRDDGSCSSLNYQLHPVIGVIYGPTGCGKSQLLRNLLSSQLISPTPETVFFIAPQVDMIPPSELKAWEMQICEGNYAPGPDGTIIPQSGTLRPRFVKMAYDDLILEHNYDVSDPRNIFAQAAARGPIAIIMDECMENLGGHKGVSKFFHAFPSKLHDKFPKCTGYTVLVVLHNMNPRRDMAGNIANLKIQSKMHLISPRMHPSQLNRFVNTYTKGLPLAISLLLKDIFRHHAQRSCYDWIIYNTTPQHEALQWCYLHPRDGLMPMYLNIQSHLYHVLEKIHRTLNDRDRWSRAYRARKTPK
InterPro domains: - IPR003389: Adenovirus packaging protein 1 (family) [3-447]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [167-333]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0097159 (organic cyclic compound binding), GO:0043167 (ion binding), GO:0097367 (carbohydrate derivative binding), GO:0003676 (nucleic acid binding), GO:1901265 (nucleoside phosphate binding), GO:0043168 (anion binding), GO:0000166 (nucleotide binding), GO:0032553 (ribonucleotide binding), GO:0035639 (purine ribonucleoside triphosphate binding), GO:0003677 (DNA binding), GO:0032555 (purine ribonucleotide binding), GO:0017076 (purine nucleotide binding), GO:0005524 (ATP binding), GO:0032559 (adenyl ribonucleotide binding), GO:0030554 (adenyl nucleotide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0016032 (viral process), GO:0019068 (virion assembly), GO:0019072 (viral genome packaging), GO:0019058 (viral life cycle)
Cellular Component (CC): GO:0005575 (cellular component), GO:0044423 (virion component), GO:0032991 (protein-containing complex), GO:0044815 (DNA packaging complex), GO:0019028 (viral capsid)
Protein: Packaging protein 3 (P04496)
Organism: Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)
Function: Involved in viral genome packaging through its interaction with packaging proteins 1 and 2. After proteolytic cleavage by adenovirus protease, L1 52/55k protein is removed from the capsid during viral maturation
Subcellular location: Host nucleus. Note=Nuclear protein present in empty capsids and assembly intermediates
Sequence: MHPVLRQMRPPPQQRQEQEQRQTCRAPSPPPTASGGATSAVDAAADGDYEPPRRRARHYLDLEEGEGLARLGAPSPERYPRVQLKRDTREAYVPRQNLFRDREGEEPEEMRDRKFHAGRELRHGLNRERLLREEDFEPDARTGISPARAHVAAADLVTAYEQTVNQEINFQKSFNNHVRTLVAREEVAIGLMHLWDFVSALEQNPNSKPLMAQLFLIVQHSRDNEAFRDALLNIVEPEGRWLLDLINILQSIVVQERSLSLADKVAAINYSMLSLGKFYARKIYHTPYVPIDKEVKIEGFYMRMALKVLTLSDDLGVYRNERIHKAVSVSRRRELSDRELMHSLQRALAGTGSGDREAESYFDAGADLRWAPSRRALEAAGAGPGLAVAPARAGNVGGVEEYDEDDEYEPEDGEY
InterPro domains: - IPR037536: Packaging protein 3 (family) [1-411]
- IPR004292: Adenoviral packaging protein 3-like (family) [72-269]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0016032 (viral process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0019058 (viral life cycle), GO:0006807 (nitrogen compound metabolic process), GO:0019079 (viral genome replication), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0039693 (viral DNA genome replication), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0090304 (nucleic acid metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0018130 (heterocycle biosynthetic process), GO:0006259 (DNA metabolic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0039687 (viral DNA strand displacement replication), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0071897 (DNA biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0044815 (DNA packaging complex)
Protein: Putative membrane protein PmrR (G3MTW7)
Organism: Escherichia coli (strain K12)
Function: May bind to BasS and modulate its sensor kinase activity
Subcellular location: Cell inner membrane; Single-pass membrane protein
Sequence: MKNRVYESLTTVFSVLVVSSFLYIWFATY
InterPro domains: - IPR049795: LpxT activity modulator PmrR (family) [1-29]
Interaction partners: - Lipid A 1-diphosphate synthase
- Phosphoethanolamine transferase EptA
- Signal transduction protein PmrD
- Transcriptional regulatory protein BasR
- Sensor protein BasS
- Kdo(2)-lipid A phosphoethanolamine 7''-transferase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0001666 (response to hypoxia), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0070482 (response to oxygen levels), GO:0071456 (cellular response to hypoxia), GO:0071453 (cellular response to oxygen levels), GO:0036293 (response to decreased oxygen levels), GO:0036294 (cellular response to decreased oxygen levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Protein PAL OF QUIRKY (Q9LF06)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Collaboratively with SUB and QKY, regulates cell growth anisotropy during gynoecium development, thus linking together cell- cell communication and cellular growth
Subcellular location: Cell membrane. Endomembrane system. Note=Localized in small cytoplasmic compartments
Sequence: MTTVSSAFATVAEGAKVVTPRWKKNERNGKLRVMCRYGGSIVSPPQTKSPRYVGGDTRIVAIPSSAETSFASLVSHLTVTLKISYPFKVKYQLPDQELDSLISVEADEDVQIMMEEHGYLSSESSIPQSRIRLFLFPLKSQQSNEAGASQGDSDQCKVETDIDWLGIEESNKPIREELTQPVLQHPKTEMWFVDALKSVEMMQTRRTNSGTSGSGDGNGGICGQESMMLETNSSFGSTSSSVSSSNLPPIKSSGEDNIANSQVKFAPIESVTSNDNSAVTPIPSHELPSHSHAFENKPSSNLYVAELNRPVPVPISGYPPFMNQAQQQHIQVIYTGQPYITGNSPMTLPATAYHHTNHVYYQRPPQPYPIYYIPVEQYSSRHVQALPVKPSTVLNYHQVDSPVVRTSSPLAPEFSSQVYPLSKPVDSSVQTSSEATLNTTSRDAFIYNTDVDDDNDIAHAQIYKSQPPAPTLPSQY
InterPro domains: - IPR053198: Gynoecium Development Regulator (family) [21-376]
- IPR000270: PB1 domain (domain) [45-138]
Interaction partners: - MATH domain and coiled-coil domain-containing protein At3g58220
- PRA1 family protein F1
- AT4G01090 protein
- Potassium transporter 13
- At4g01410
- Protein kinase superfamily protein
- F19P19.6 protein
- PRA1 family protein B1
- Histidine containing phosphotransfer protein
- PRA1 family protein D
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0006950 (response to stress), GO:0090693 (plant organ senescence), GO:0042221 (response to chemical), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006952 (defense response), GO:0099402 (plant organ development), GO:0010035 (response to inorganic substance), GO:0043207 (response to external biotic stimulus), GO:0010150 (leaf senescence), GO:0006979 (response to oxidative stress), GO:0010033 (response to organic substance), GO:0048731 (system development), GO:0098542 (defense response to other organism), GO:0048367 (shoot system development), GO:0048827 (phyllome development), GO:0010193 (response to ozone), GO:0000302 (response to reactive oxygen species), GO:0048366 (leaf development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Uncharacterized PPE family protein PPE25 (P9WI13)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Sequence: MDFGALPPEINSGRMYCGPGSGPMLAAAAAWDGVAVELGLAATGYASVIAELTGAPWVGAASLSMVAAATPYVAWLSQAAARAEQAGMQAAAAAAAYEAAFVMTVPPPVITANRVLVMTLIATNFFGQNSAAIAVAEAQYAEMWAQDAVAMYGYAAASASASRLIPFAAPPKTTNSAGVVAQVAAVAAMPGLLQRLSSAASVSWSNPNDWWLVRLLGSITPTERTTIVRLLGQSYFATGMAQFFASIAQQLTFGPGGTTAGSGGAWYPTPQFAGLGASRAVSASLARANKIGALSVPPSWVKTTALTESPVAHAVSANPTVGSSHGPHGLLRGLPLGSRITRRSGAFAHRYGFRHSVVARPPSAG
InterPro domains: - IPR022171: PPE family, C-terminal (domain) [282-361]
- IPR000030: PPE domain (domain) [2-164]
- IPR038332: PPE superfamily (homologous_superfamily) [1-174]
Interaction partners: - PE family protein PE19
- PE family protein PE18
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005618 (cell wall), GO:0009274 (peptidoglycan-based cell wall)