Protein: Sporulation protein kinase pit1 (EC 2.7.11.1) (O14132)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Protein kinase which is essential for spore formation.
Sequence: MKKYLWGTPTTNTVFTGKQPKYTKEVRKCISIDEVYNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVSDATRLREVHSLLRLSENENIVNIFDLYIDQFRCLHIVMEFLDCNLYQLISTRKNDPLTLEQVQDIMRQIFKGLNHIHTNGFFHRDMKPENILISSNSDSSSFNVKIADFGLAREINSRPPYTEYVSTRWYRAPELLLRDSYYSFPVDIYAAGCMAFEIATLQPIFPGNDDFDQLYKMCEILGSPDEQSQNTGDKGGGIWDRAELLANKLGISLPKMAPLDFGDLFSPPWNLAFASMLSQLLKWDPAKRPTAEMCLDLEFCRVSAPADAVASKEEVNKNTDFRVSISYFPSSSSIPDECNTEEESRINPSTSKFLKQLNKGFNGFTKPFRKSRKQSKNRKNKSSVATQFSEESEDIADSITSSTFFPVLPQIRPSTPLNLKLRNFIISSSEDSTSPKAKEFDRPLPSTEFLVAINKSQEALLNNSPNSKSGSTQLSASTCLSDLISPQLSILSHEDKRENQSVNSESSKYSPRSSNHSPTLHSKDLHRDMATVNNYAKSPPSFHATQDLLRKTLAYTNSSGTSTVLSNDSSAISSTFLDRDFPDFGITSLAGSLTLPDSKIIDRSKTHVSTQLLP
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [32-336]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [157-169]
- IPR050117: Mitogen-activated protein (MAP) kinase (family) [36-401]
- IPR017441: Protein kinase, ATP binding site (binding_site) [42-66]
- IPR000719: Protein kinase domain (domain) [36-336]
Interaction partners: - Sporulation protein kinase mde3
- DNA replication licensing factor mcm3
- DNA replication licensing factor mcm5
- DNA replication licensing factor mcm7
- DNA replication licensing factor mcm4
- Origin recognition complex subunit 3
- Cell division control protein 18
- Cell division cycle protein cdt1
- Origin recognition complex subunit 2
- DNA replication licensing factor mcm6
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0031137 (regulation of conjugation with cellular fusion), GO:0031139 (positive regulation of conjugation with cellular fusion), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0035556 (intracellular signal transduction), GO:0019932 (second-messenger-mediated signaling), GO:0019722 (calcium-mediated signaling)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030428 (cell septum), GO:0005829 (cytosol), GO:0030427 (site of polarized growth), GO:0071944 (cell periphery), GO:0060187 (cell pole), GO:0032153 (cell division site), GO:0005737 (cytoplasm), GO:0051286 (cell tip), GO:0043229 (intracellular organelle), GO:0005938 (cell cortex), GO:0099568 (cytoplasmic region), GO:0043228 (non-membrane-bounded organelle), GO:0000935 (division septum), GO:0031097 (medial cortex), GO:0035838 (growing cell tip), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0099738 (cell cortex region), GO:0051285 (cell cortex of cell tip), GO:0005634 (nucleus), GO:0005856 (cytoskeleton), GO:0005819 (spindle), GO:0072686 (mitotic spindle), GO:0015630 (microtubule cytoskeleton)