Protein: Lymphocyte enhancer binding factor 1 (Lymphoid enhancer-binding factor 1) (Q9W7C0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MPQLSGGGGGGDPELCATDEMIPFKDEGDPHKEQIFAEISHSEEEGDLAEIKSSLVNETEISPNSNSHDAARQSQITPDSYHEKHRDHPDDGKLQDLYSKGHPYPSYPGYIMMTNMNNEPYMNNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFAPGPHSGHHPQDVNPKQAGMPRHHPGPDIPNFYPLSPGGVGQMTPPLGWFSHHMVPGPPGPHATGIPHPAIVNPQVKQEHDTDLMHMKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKIQEPASGTGQRMKTAYI
InterPro domains: - IPR027397: Catenin binding domain superfamily (homologous_superfamily) [1-63]
- IPR024940: Transcription factor TCF/LEF (family) [211-352]
- IPR009071: High mobility group box domain (domain) [264-334]
- IPR036910: High mobility group box domain superfamily (homologous_superfamily) [263-348]
- IPR013558: CTNNB1 binding, N-teminal (domain) [7-210]
Interaction partners: - Catenin beta-1
- Catenin, beta 2.
- Transducin-like enhancer protein 3-A
- Mitogen-activated protein kinase
- Mitogen-activated protein kinase
- Mothers against decapentaplegic homolog.
- Axin-2
- C-terminal-binding protein 1
- C-terminal-binding protein 1
- Mothers against decapentaplegic homolog.
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0043473 (pigmentation), GO:0048519 (negative regulation of biological process), GO:0048856 (anatomical structure development), GO:0048870 (cell motility), GO:0009653 (anatomical structure morphogenesis), GO:0007389 (pattern specification process), GO:0007267 (cell-cell signaling), GO:0050793 (regulation of developmental process), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0048066 (developmental pigmentation), GO:0048523 (negative regulation of cellular process), GO:0007165 (signal transduction), GO:0048869 (cellular developmental process), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0008283 (cell population proliferation), GO:0009893 (positive regulation of metabolic process), GO:0051094 (positive regulation of developmental process), GO:0007154 (cell communication), GO:0048522 (positive regulation of cellular process), GO:0048729 (tissue morphogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0060255 (regulation of macromolecule metabolic process), GO:0035295 (tube development), GO:0009887 (animal organ morphogenesis), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0045595 (regulation of cell differentiation), GO:0007166 (cell surface receptor signaling pathway), GO:0009790 (embryo development), GO:0050931 (pigment cell differentiation), GO:1904888 (cranial skeletal system development), GO:0016477 (cell migration), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0035239 (tube morphogenesis), GO:0045597 (positive regulation of cell differentiation), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0198738 (cell-cell signaling by wnt), GO:1905114 (cell surface receptor signaling pathway involved in cell-cell signaling), GO:0030902 (hindbrain development), GO:0009891 (positive regulation of biosynthetic process), GO:0045165 (cell fate commitment), GO:0001709 (cell fate determination), GO:0048598 (embryonic morphogenesis), GO:0042127 (regulation of cell population proliferation), GO:0021536 (diencephalon development), GO:0009888 (tissue development), GO:0003002 (regionalization), GO:0060322 (head development), GO:0031325 (positive regulation of cellular metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0030318 (melanocyte differentiation), GO:0021510 (spinal cord development), GO:0051216 (cartilage development), GO:0048864 (stem cell development), GO:0060562 (epithelial tube morphogenesis), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0016055 (Wnt signaling pathway), GO:0061448 (connective tissue development), GO:0007369 (gastrulation), GO:0060027 (convergent extension involved in gastrulation), GO:0048701 (embryonic cranial skeleton morphogenesis), GO:0030318 (melanocyte differentiation), GO:0010001 (glial cell differentiation), GO:0002009 (morphogenesis of an epithelium), GO:0010468 (regulation of gene expression), GO:0007420 (brain development), GO:0048703 (embryonic viscerocranium morphogenesis), GO:0048568 (embryonic organ development), GO:0007399 (nervous system development), GO:0001501 (skeletal system development), GO:0072359 (circulatory system development), GO:0007417 (central nervous system development), GO:0009953 (dorsal/ventral pattern formation), GO:0051252 (regulation of RNA metabolic process), GO:0048762 (mesenchymal cell differentiation), GO:0007507 (heart development), GO:0048483 (autonomic nervous system development), GO:0072001 (renal system development), GO:0035270 (endocrine system development), GO:0071599 (otic vesicle development), GO:0048864 (stem cell development), GO:0042472 (inner ear morphogenesis), GO:0021915 (neural tube development), GO:0048562 (embryonic organ morphogenesis), GO:0060485 (mesenchyme development), GO:0001667 (ameboidal-type cell migration), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0048863 (stem cell differentiation), GO:0051254 (positive regulation of RNA metabolic process), GO:0048863 (stem cell differentiation), GO:0032965 (regulation of collagen biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0014033 (neural crest cell differentiation), GO:0060429 (epithelium development), GO:0001822 (kidney development), GO:0031328 (positive regulation of cellular biosynthetic process), GO:0014033 (neural crest cell differentiation), GO:0048709 (oligodendrocyte differentiation), GO:2001141 (regulation of RNA biosynthetic process), GO:0090497 (mesenchymal cell migration), GO:0060070 (canonical Wnt signaling pathway), GO:1902680 (positive regulation of RNA biosynthetic process), GO:0014032 (neural crest cell development), GO:0090497 (mesenchymal cell migration), GO:0006355 (regulation of DNA-templated transcription), GO:0014032 (neural crest cell development), GO:0071773 (cellular response to BMP stimulus), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0001755 (neural crest cell migration), GO:0006357 (regulation of transcription by RNA polymerase II), GO:0045893 (positive regulation of DNA-templated transcription), GO:0001755 (neural crest cell migration), GO:0045944 (positive regulation of transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)