Protein: serine C-palmitoyltransferase (EC 2.3.1.50) (Q38BJ5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MPTYVEAENFLDAPRGAVVANKAVTEAESCDEAYNKQGSVRASFAANGATDTICQKESVGTHTQPKRVTHQEEEHKSIPFISVVMTYFTFLLLFTFGCIAELRRKLFGAKRKQREGYASLLTFLEYFWQNHFYRRARDCFNHAIDSRPSRVIGVMERVSTDSNRTFSFTGNIKPCVNLSSYNYLGFADDIPHITREVLNSLDRYGLASCSAAQHAGQHGPVSKLERAIADFLKKEDAVVCGMGFGTNFRGLPALFGEDTLVVSDSLNHSSLVNGIRLSGARAKVFKNADMNSLEKVLREAVVLGQNPKGAYVPWTRIVIVVEGVYSMEGEFVNLPRVVELKKKYGALLFVDEAHSIGATGRTGRGVTEHFGVDPRDVDILMGTFTKSFGAIGGYLAGDQSVIDHIRTHSSLALHCDTLSPPCAQQALSVLDVLNGNDGTDIGPKHIQQLMENSRFFRQGLIDRGFSVLGNDASPVVPVMLYHLGRAIAVWRKCMRRGLAIVIVGYPATPLLGCRIRFCVSAAHTRADLQFALDVMDQIKKETNIQFLPSTVPPQGEE
InterPro domains: - IPR001917: Aminotransferase, class-II, pyridoxal-phosphate binding site (binding_site) [383-392]
- IPR015421: Pyridoxal phosphate-dependent transferase, major domain (homologous_superfamily) [189-442]
- IPR050087: 8-amino-7-oxononanoate synthase class-II (family) [93-537]
- IPR004839: Aminotransferase, class I/classII, large domain (domain) [174-533]
- IPR015424: Pyridoxal phosphate-dependent transferase (homologous_superfamily) [159-543]
- IPR015422: Pyridoxal phosphate-dependent transferase, small domain (homologous_superfamily) [171-535]
Interaction partners: - Serine-palmitoyl-CoA transferase, putative
- 3-dehydrosphinganine reductase
- Cystathionine beta-synthase, putative
- Phosphatidylcholine:ceramide cholinephosphotransferase 4
- Phosphatidylethanolamine:ceramide ethanolaminephosphotransferase
- Phosphatidylcholine:ceramide cholinephosphotransferase 3
- Phosphatidylinositol:ceramide inositolphosphotransferase
- Sphingomyelin phosphodiesterase, putative
- sphingolipid 4-desaturase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016408 (C-acyltransferase activity), GO:0016409 (palmitoyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006066 (alcohol metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0019751 (polyol metabolic process), GO:0006643 (membrane lipid metabolic process), GO:1901617 (organic hydroxy compound biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0046467 (membrane lipid biosynthetic process), GO:0046165 (alcohol biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0006665 (sphingolipid metabolic process), GO:0046519 (sphingoid metabolic process), GO:0034311 (diol metabolic process), GO:0030148 (sphingolipid biosynthetic process), GO:0046173 (polyol biosynthetic process), GO:0046512 (sphingosine biosynthetic process), GO:0034312 (diol biosynthetic process), GO:0046520 (sphingoid biosynthetic process), GO:0006670 (sphingosine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)