Protein: Protocadherin 1 (Q2TJH4)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Sequence: MGPLRPSPGPGGQRLLLPPLLLALLLLLAPSASHTTQVVYKVPEEQPPNTLIGSLAADYGLPDVGHLYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQIPGNPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSDQGANA
InterPro domains: - IPR050174: Protocadherin/Cadherin-related Cell Adhesion (family) [25-291]
- IPR002126: Cadherin-like (domain) [34-269]
- IPR013164: Cadherin, N-terminal (domain) [38-118]
- IPR015919: Cadherin-like superfamily (homologous_superfamily) [36-291]
- IPR020894: Cadherin conserved site (conserved_site) [246-256]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0003008 (system process), GO:0050793 (regulation of developmental process), GO:0065008 (regulation of biological quality), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0001503 (ossification), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0035556 (intracellular signal transduction), GO:0001568 (blood vessel development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0008217 (regulation of blood pressure), GO:0003013 (circulatory system process), GO:0043114 (regulation of vascular permeability), GO:0035295 (tube development), GO:0009887 (animal organ morphogenesis), GO:2000026 (regulation of multicellular organismal development), GO:0009888 (tissue development), GO:0007186 (G protein-coupled receptor signaling pathway), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0009790 (embryo development), GO:0072006 (nephron development), GO:0032835 (glomerulus development), GO:0072001 (renal system development), GO:0008015 (blood circulation), GO:0001944 (vasculature development), GO:0097205 (renal filtration), GO:0061005 (cell differentiation involved in kidney development), GO:0045777 (positive regulation of blood pressure), GO:0060485 (mesenchyme development), GO:0060993 (kidney morphogenesis), GO:0007219 (Notch signaling pathway), GO:0030855 (epithelial cell differentiation), GO:0048863 (stem cell differentiation), GO:0003007 (heart morphogenesis), GO:0048514 (blood vessel morphogenesis), GO:0002064 (epithelial cell development), GO:0072359 (circulatory system development), GO:0001570 (vasculogenesis), GO:0072010 (glomerular epithelium development), GO:0003071 (renal system process involved in regulation of systemic arterial blood pressure), GO:0060429 (epithelium development), GO:0001822 (kidney development), GO:0072012 (glomerulus vasculature development), GO:0009792 (embryo development ending in birth or egg hatching), GO:0030856 (regulation of epithelial cell differentiation), GO:0043009 (chordate embryonic development), GO:0035850 (epithelial cell differentiation involved in kidney development), GO:0003094 (glomerular filtration), GO:0072310 (glomerular epithelial cell development), GO:0072311 (glomerular epithelial cell differentiation), GO:0072112 (podocyte differentiation), GO:0072073 (kidney epithelium development), GO:0045601 (regulation of endothelial cell differentiation), GO:0048706 (embryonic skeletal system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0005886 (plasma membrane), GO:0005911 (cell-cell junction)