wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Protein RAFTIN 1B (TaRAFTIN1b) (BURP domain-containing protein 1B) (Q70KG3)
Organism: Triticum aestivum (Wheat)
Function: Required for pollen development. Probably synthesized in the tapetum, packaged in Ubisch bodies and transported at appropriate stages to the micropsores.
Sequence: MARFLVALLAATLVAVQAGGQLGHAAPATGEVFWRAVLPHSPLPDAVLRLLKQPAAESTSFVRDPEDRPPFDYRDYSRSSSDDEPSKSTVAASGAGGFDYDNYSGADERRGATDEYKAPSSSLAGSGAYMARGGKAETTTVFFHEEAVRVGRRLPFHFPPATPAALGFLPRQVADSVPFTTAALPGILATFGIASDSTTVPSMEATLRACESPTIAGESKFCATSLEALVERAMGVLGTRDIRPVTSTLPRAGAPLQTYTVVAVQPVEGGPVFVACHDEAYPYTVYRCHTTGPSRAYTVDMEGARGADAVTIAAVCHTDTSLWNPEHVSFKLLGTKPGGTPVCHLMPYGHIIWAKNVKRSPA
InterPro domains: - IPR044816: BURP domain-containing protein (family) [25-355]
- IPR004873: BURP domain (domain) [140-356]
Interaction partners: - RING-type E3 ubiquitin transferase
- RING-type E3 ubiquitin transferase
- RING-type E3 ubiquitin transferase
- Serine/threonine-protein phosphatase
- Serine/threonine-protein phosphatase
- Serine/threonine-protein phosphatase
- Serine/threonine-protein phosphatase
- Serine/threonine-protein phosphatase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016787 (hydrolase activity), GO:0140098 (catalytic activity, acting on RNA), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0004518 (nuclease activity), GO:0004540 (ribonuclease activity)
Biological Process (BP): GO:0008150 (biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0021700 (developmental maturation), GO:0007275 (multicellular organism development), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0009791 (post-embryonic development), GO:0048316 (seed development), GO:0016043 (cellular component organization), GO:0010431 (seed maturation), GO:0048608 (reproductive structure development), GO:0044085 (cellular component biogenesis), GO:0071695 (anatomical structure maturation), GO:0048731 (system development), GO:0071695 (anatomical structure maturation), GO:0061458 (reproductive system development), GO:0006996 (organelle organization), GO:0010154 (fruit development), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0016050 (vesicle organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix)
Protein: AT3g62570/T12C14_270 (Tetratricopeptide repeat (TPR)-like superfamily protein) (Q8W591)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MAIYSVHNGDKKHWWFTHKKIVDKYIKDARSLMESEEQNDVASAIHLLDAALSISPRSETALELKARSLLFLRRFKDVVDMLQDYIPSLKLAVNEEDGSYSYEGSSYSSSSSQLSRKLLSDSSPRRDSSFKCFSVSYLKKKIMAGICKNRDQDKQWRYVVLGQACCHLGLMEDALVLLQTGKRLATVEFRRLSVSLSDDSVSLLLSESSSSSSSSSYAFPPRKVSECETVTNLLAHTKNLLRRRSAGFAAFDAGLFADSIRHFSKILDGRRRPAPQGFLADCYMHRAAAYKSAGKIAEAIADCNKTLALEPSCIHALETRATLLETVRCLPDSLHDLEHLKILYNTILRDRKLPGPPWKRHNVKYREIPGKLCELTTKSKKLKAKMANGEIGNVDYYGLVGVRRGCTRSELDRANLLLCLRHKPDKALAFMERCDFFDQSEISSVKDRAKMSSLLLYRLIQRGYTALAAAIAEEEQRKKMMVLTQMSTKTVEEHEPVEKSGSITLTDFAEIKPGNSNAYQGVFCRDLAAVGSLLSRTGFNQPIPMKYDAISC
InterPro domains: - IPR001623: DnaJ domain (domain) [395-439]
- IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [15-340]
- IPR019734: Tetratricopeptide repeat (repeat) [280-313]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048589 (developmental growth), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0016049 (cell growth), GO:0021700 (developmental maturation), GO:0099402 (plant organ development), GO:0048588 (developmental cell growth), GO:1905392 (plant organ morphogenesis), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0060560 (developmental growth involved in morphogenesis), GO:0030154 (cell differentiation), GO:0048469 (cell maturation), GO:0048731 (system development), GO:0071695 (anatomical structure maturation), GO:0048364 (root development), GO:0048764 (trichoblast maturation), GO:0010015 (root morphogenesis), GO:0080147 (root hair cell development), GO:0090558 (plant epidermis development), GO:0090627 (plant epidermal cell differentiation), GO:0048767 (root hair elongation), GO:0022622 (root system development), GO:0010053 (root epidermal cell differentiation), GO:0048765 (root hair cell differentiation), GO:0010054 (trichoblast differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Alcohol dehydrogenase 1A (EC 1.1.1.1) (Alcohol dehydrogenase subunit alpha) (P07327)
Organism: Homo sapiens (Human)
Function: Alcohol dehydrogenase. Oxidizes primary as well as secondary alcohols. Ethanol is a very poor substrate.
Subcellular location: Cytoplasm.
Sequence: MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTILMF
InterPro domains: - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [166-339]
- IPR020843: Enoylreductase domain (domain) [17-373]
- IPR013149: Alcohol dehydrogenase-like, C-terminal (domain) [203-334]
- IPR011032: GroES-like superfamily (homologous_superfamily) [3-375]
- IPR013154: Alcohol dehydrogenase-like, N-terminal (domain) [34-162]
- IPR002328: Alcohol dehydrogenase, zinc-type, conserved site (conserved_site) [67-81]
Interaction partners: - All-trans-retinol dehydrogenase [NAD
- Alcohol dehydrogenase 1C
- Aldehyde dehydrogenase, mitochondrial
- Cytochrome P450 2E1
- Vasopressin-neurophysin 2-copeptin
- Aldehyde dehydrogenase 1A1
- Aldehyde oxidase
- Cytochrome P450 26A1
- Amine oxidase [flavin-containing] A
- Lecithin retinol acyltransferase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor), GO:0018455 (alcohol dehydrogenase [NAD(P)+] activity), GO:0004022 (alcohol dehydrogenase (NAD+) activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044281 (small molecule metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:0006066 (alcohol metabolic process), GO:0006091 (generation of precursor metabolites and energy), GO:0034308 (primary alcohol metabolic process), GO:0006067 (ethanol metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005829 (cytosol), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Four and a half LIM domains 1 (A0A0D9SFZ9)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGIT
InterPro domains: - IPR056807: FHL1/2/3/5, N-terminal LIM domain (domain) [6-33]
- IPR042997: Four and a half LIM domains protein 1 (family) [1-175]
- IPR001781: Zinc finger, LIM-type (domain) [38-160]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0048856 (anatomical structure development), GO:0061061 (muscle structure development), GO:0048513 (animal organ development), GO:0007517 (muscle organ development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Arylsulfatase (AS) (EC 3.1.6.1) (Aryl-sulfate sulphohydrolase) (P51691)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Hydrolyzes the bond between sulfate and the aromatic ring in a compound such as 4-nitrocatechol sulfate.
Subcellular location: Cytoplasm {ECO:0000305}.
Sequence: MSKRPNFLVIVADDLGFSDIGAFGGEIATPNLDALAIAGLRLTDFHTASTCSPTRSMLLTGTDHHIAGIGTMAEALTPELEGKPGYEGHLNERVVALPELLREAGYQTLMAGKWHLGLKPEQTPHARGFERSFSLLPGAANHYGFEPPYDESTPRILKGTPALYVEDERYLDTLPEGFYSSDAFGDKLLQYLKERDQSRPFFAYLPFSAPHWPLQAPREIVEKYRGRYDAGPEALRQERLARLKELGLVEADVEAHPVLALTREWEALEDEERAKSARAMEVYAAMVERMDWNIGRVVDYLRRQGELDNTFVLFMSDNGAEGALLEAFPKFGPDLLGFLDRHYDNSLENIGRANSYVWYGPRWAQAATAPSRLYKAFTTQGGIRVPALVRYPRLSRQGAISHAFATVMDVTPTLLDLAGVRHPGKRWRGREIAEPRGRSWLGWLSGETEAAHDENTVTGWELFGMRAIRQGDWKAVYLPAPVGPATWQLYDLARDPGEIHDLADSQPGKLAELIEHWKRYVSETGVVEGASPFLVR
InterPro domains: - IPR017850: Alkaline-phosphatase-like, core domain superfamily (homologous_superfamily) [1-526]
- IPR050738: Sulfatase enzyme (family) [3-523]
- IPR024607: Sulfatase, conserved site (conserved_site) [49-115]
- IPR000917: Sulfatase, N-terminal (domain) [5-420]
Interaction partners: - Linear primary-alkylsulfatase
- Probable permease of ABC transporter
- TauD/TfdA-like domain-containing protein
- Probable TonB-dependent receptor
- Probable ATP-binding component of ABC transporter
- Probable binding protein component of ABC transporter
- Hydroxyacylglutathione hydrolase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0008484 (sulfuric ester hydrolase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:1901700 (response to oxygen-containing compound), GO:0033993 (response to lipid), GO:0014070 (response to organic cyclic compound)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Histone-lysine N-methyltransferase, putative (EC 2.1.1.43) (Q8I5R3)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Not known
Sequence: MILFKRNFHNYFANNFIKDLFKKSQHISFNDIQKKIYIGKSSLGGLGVFSLEGIKKNEIIEICPTVSICNEEIPRNLVDYLYEGKEPSKNKAIVDIIINRKKETSNYKLLPLGYGILYNHSDIPNAYVEIHKINKNQIKQKQDVTVSNNVMIVYAYNNIQKDDEILISYGHSWWKVSS
InterPro domains: - IPR009207: Histone-lysine N-methyltransferase, H3 lysine-37 specific (family) [27-178]
- IPR046341: SET domain superfamily (homologous_superfamily) [30-175]
- IPR001214: SET domain (domain) [34-176]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0008276 (protein methyltransferase activity), GO:0016279 (protein-lysine N-methyltransferase activity), GO:0008168 (methyltransferase activity), GO:0042054 (histone methyltransferase activity), GO:0018024 (histone lysine N-methyltransferase activity), GO:0140938 (histone H3 methyltransferase activity), GO:0008757 (S-adenosylmethionine-dependent methyltransferase activity), GO:0008170 (N-methyltransferase activity), GO:0016278 (lysine N-methyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0032259 (methylation), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0043414 (macromolecule methylation), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0006479 (protein methylation), GO:0008213 (protein alkylation), GO:0018022 (peptidyl-lysine methylation), GO:0018193 (peptidyl-amino acid modification), GO:0018205 (peptidyl-lysine modification), GO:0018023 (peptidyl-lysine trimethylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Maltooligosaccharide ABC transporter solute-binding lipoprotein (Maltodextrin-binding protein) (Solute-binding protein MalX) (P59213)
Organism: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Function: Part of an ABC transporter complex involved in the uptake of maltodextrins. Binds glycogen-derived linear maltooligosaccharides increasing in size from maltotriose to maltooctaose with the highest affinity for maltotriose. Has a very weak affinity for maltose. Has also a very low affinity for maltotetraitol, indicating that the binding is selective for maltooligosaccharides with an intact reducing end.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}.
Sequence: MSSKFMKSAAVLGTATLASLLLVACGSKTADKPADSGSSEVKELTVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPYDRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVKDAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKDAKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKAQAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQKVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNMLFDAVSGQKDAKTAANDAVTLIKETIKQKFGE
InterPro domains: - IPR006061: Solute-binding family 1, conserved site (conserved_site) [144-161]
- IPR006059: Bacterial-type extracellular solute-binding protein (family) [59-360]
- IPR006060: Maltose/Cyclodextrin ABC transporter, substrate-binding protein (family) [141-395]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:0015695 (organic cation transport), GO:0015697 (quaternary ammonium group transport), GO:0015840 (urea transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030312 (external encapsulating structure), GO:0005618 (cell wall), GO:0005886 (plasma membrane), GO:0009274 (peptidoglycan-based cell wall)
Protein: Bacterial proteasome activator (P9WKX3)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Interacts with the core proteasome alpha-subunit (PrcA) through its C-terminal hydrophobic-tyrosine-X motif (HbYX motif). Interaction of Bpa with the proteasome stimulates proteosomal peptidase and casein degradation activity, which suggests Bpa could play a role in the removal of non-native or damaged proteins by influencing the conformation of the proteasome complex upon interaction. Can inhibit degradation of Pup-tagged substrates in vitro by competing with Mpa for association with the proteasome.
Sequence: MVIGLSTGSDDDDVEVIGGVDPRLIAVQENDSDESSLTDLVEQPAKVMRIGTMIKQLLEEVRAAPLDEASRNRLRDIHATSIRELEDGLAPELREELDRLTLPFNEDAVPSDAELRIAQAQLVGWLEGLFHGIQTALFAQQMAARAQLQQMRQGALPPGVGKSGQHGHGTGQYL
InterPro domains: - IPR019695: Bacterial proteasome activator (family) [28-167]
Interaction partners: - Proteasome-associated ATPase
- Proteasome subunit alpha
- Probable O-antigen/lipopolysaccharide transport ATP-binding protein ABC transporter RfbE
- Probable O-antigen/lipopolysaccharide transport integral membrane protein ABC transporter RfbD
- Proteasome subunit beta
- Galactofuranosyltransferase GlfT1
- Probable conserved transmembrane protein alanine and leucine rich
- Pup deamidase/depupylase
- Pup--protein ligase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0044877 (protein-containing complex binding), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0008233 (peptidase activity), GO:0004175 (endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0007154 (cell communication), GO:0009408 (response to heat), GO:0009266 (response to temperature stimulus), GO:0009991 (response to extracellular stimulus), GO:1901700 (response to oxygen-containing compound), GO:0031668 (cellular response to extracellular stimulus), GO:0010035 (response to inorganic substance), GO:0042594 (response to starvation), GO:0071496 (cellular response to external stimulus), GO:0033554 (cellular response to stress), GO:0070482 (response to oxygen levels), GO:1902074 (response to salt), GO:0010167 (response to nitrate), GO:0031669 (cellular response to nutrient levels), GO:0009267 (cellular response to starvation), GO:0031667 (response to nutrient levels), GO:0036293 (response to decreased oxygen levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030312 (external encapsulating structure), GO:0005618 (cell wall), GO:0005886 (plasma membrane), GO:0009274 (peptidoglycan-based cell wall)
Protein: Flavonol synthase 3 (AtFLS3) (EC 1.14.20.6) (Q9FFQ5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Catalyzes the formation of flavonols from dihydroflavonols. Possesses low activity in vitro towards dihydrokaempferol and dihydroquercetin producing kaempferol and quercitin, respectively.
Sequence: MEMEKNQHISSLDIPVIDLSNPDEELVASAVVKASQEWGIFQVVNHGIPTELILRLLQVGMEFFELPETEKEAVAKPEDSLDIEGYRTKYQKDLEGRNAWVDHLFHRIWPPSRVNHKFWPKNPPEYIEVNEEYASHIKKLSEKIMEWLSEGLGLRHEALKEGLGGETIEYLMKINYYPPCPDPELVVGAPDHTDVNGITLLVANEALGLQAFKDNQWIDAEYTTSGIIVIIGDQFLRMSNGKYKSVEHRAKMDKEKTRISWPVFVESSLDQVFGPLPELITGDENVPKFKPYVYKDYKFRKLKKLLLD
InterPro domains: - IPR026992: Non-haem dioxygenase, N-terminal domain (domain) [14-121]
- IPR050295: Plant 2-oxoglutarate-dependent oxidoreductases (family) [9-298]
- IPR005123: Oxoglutarate/iron-dependent dioxygenase domain (domain) [167-267]
- IPR044861: Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain (domain) [169-266]
- IPR027443: Isopenicillin N synthase-like superfamily (homologous_superfamily) [1-305]
Interaction partners: - Dihydroflavonol 4-reductase
- Flavonoid 3'-monooxygenase
- Flavonol 3-O-glucosyltransferase
- Chalcone synthase
- Naringenin,2-oxoglutarate 3-dioxygenase
- 2-oxoglutarate
- Anthocyanidin reductase
- Leucoanthocyanidin dioxygenase
- Phenylalanine ammonia-lyase 4
- Phenylalanine ammonia-lyase 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0051213 (dioxygenase activity), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen), GO:0016706 (2-oxoglutarate-dependent dioxygenase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0019748 (secondary metabolic process), GO:0071704 (organic substance metabolic process), GO:0044550 (secondary metabolite biosynthetic process), GO:0010035 (response to inorganic substance), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0046483 (heterocycle metabolic process), GO:0009698 (phenylpropanoid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0010038 (response to metal ion), GO:0009804 (coumarin metabolic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0019438 (aromatic compound biosynthetic process), GO:0018130 (heterocycle biosynthetic process), GO:0009699 (phenylpropanoid biosynthetic process), GO:0010039 (response to iron ion), GO:0009805 (coumarin biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Sulfhydryl oxidase (EC 1.8.3.2) (Q9ICB8)
Organism: African swine fever virus (ASFV)
Function: Not known
Sequence: MLHWGPKYWRALHLYAIFFSDAPGWKEKYEAIQWILNFIESLPCTRCRHHAFSYLTKNPLTLNNSEDFQYWTFAFHNNVNNRLNKKIISWSEYKNIYEQSILKTIEYGKTDFIGAWSSL
InterPro domains: - IPR017905: ERV/ALR sulfhydryl oxidase domain (domain) [1-97]
- IPR039799: Sulfhydryl oxidase ALR/ERV (family) [5-99]
- IPR036774: ERV/ALR sulfhydryl oxidase domain superfamily (homologous_superfamily) [1-103]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0042742 (defense response to bacterium), GO:0050829 (defense response to Gram-negative bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)