Protein: Gigaxonin (A0A2I4KBP1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MSDPKRAGADAGSVVSDPQHSQKLLRVLQSFRQDDCFQDAVLVLEGEQIPVQKNILAAASPYIRTKLNYNPPKEDGSVYTIELQGIAVTTMRQILDYIFSGEITLSEDTIQDVVQAADLLLLTDLKSLCCQFLESCITAENCIGIRVFSLHYCLHHVYHVATEFLQTHFRDVANTEEFLEQPPDRLCELLSMEKLNVGNERHVLEAVVRWIGHDTEARRVHMKEVMSAVWVQGLDQSYLQEQMLGDSLMREVIGNCCMESLGGAAQQGEALLAAFKPRGYSECIVTVGGEERTSRKPTAVARCMCPLYDRNRQLWIDLMPMKERRVGHGVVSAEGYVFAIGGMDENKTVLSSGEKFDPETNTWTQIPSMMQARQHFGIAELDGMIYVLGGENEDTEVLLTMEVFDPHCNVWRMLPKMTTVRKFGSCATMKKRLYVMGGGSYGKIYDSVECYDPKTQQWTTVCPLKERRFGAVACGIGQELYVFGGVRNRDADNPESSQMTICKSEFFHDELKRWVLLDDQNLCIHTTSSFVYGAVPIGASIYVVGELDTGTSFDYVREFRRSTGTWHPTRPLMPSDLSKTSCAALRIANCKLFRLQLQQGQFRIRVPST
InterPro domains: - IPR017096: BTB-kelch protein (family) [12-586]
- IPR011333: SKP1/BTB/POZ domain superfamily (homologous_superfamily) [14-140]
- IPR011705: BTB/Kelch-associated (domain) [142-244]
- IPR000210: BTB/POZ domain (domain) [28-137]
- IPR047070: Gigaxonin, BTB/POZ domain (domain) [24-134]
- IPR015915: Kelch-type beta-propeller (homologous_superfamily) [274-588]
- IPR006652: Kelch repeat type 1 (repeat) [283-587]
- IPR030579: Gigaxonin, BACK domain (domain) [138-234]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0009653 (anatomical structure morphogenesis), GO:0071840 (cellular component organization or biogenesis), GO:0030029 (actin filament-based process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0032989 (cellular component morphogenesis), GO:0061061 (muscle structure development), GO:0044085 (cellular component biogenesis), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048513 (animal organ development), GO:0016043 (cellular component organization), GO:0030036 (actin cytoskeleton organization), GO:0010927 (cellular component assembly involved in morphogenesis), GO:0042692 (muscle cell differentiation), GO:0055001 (muscle cell development), GO:0060537 (muscle tissue development), GO:0007517 (muscle organ development), GO:0006996 (organelle organization), GO:0031032 (actomyosin structure organization), GO:0030239 (myofibril assembly), GO:0097435 (supramolecular fiber organization), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0007519 (skeletal muscle tissue development), GO:0007010 (cytoskeleton organization), GO:0051146 (striated muscle cell differentiation), GO:0060538 (skeletal muscle organ development), GO:0014904 (myotube cell development), GO:0055002 (striated muscle cell development), GO:0045214 (sarcomere organization), GO:0140694 (non-membrane-bounded organelle assembly), GO:0014902 (myotube differentiation), GO:0048741 (skeletal muscle fiber development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:1902494 (catalytic complex), GO:0140535 (intracellular protein-containing complex), GO:1990234 (transferase complex), GO:0000151 (ubiquitin ligase complex), GO:0031461 (cullin-RING ubiquitin ligase complex), GO:0031463 (Cul3-RING ubiquitin ligase complex)