Protein: Synuclein alpha interacting protein (D6R9G8)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MEAPEYLDLDEIDFSDDISYSVTSLKTIPELCRRCDTQNEDRSVSSSSWNCGISTLITNTQKPTGIADVYSKFRPVKRVSPLKHQPETLENNESDDQKNQKVVEYQKGGESDLGPQPQELGPGDGVGGPPGKSSEPSTSLGELEHYDLDMDEILDVPYIKSSQQLASFTKVTSEKRILGLCTTINGLSGKACSTGSSESSSSNMAPFCVLSPVKSPHLRKASAVIHDQHKLSTEETEISPPLVKCGSAYEPENQSKDFLNKTFSDPHGRKVEKTTPDCQLRAFHLQSSAAESKPEEQVSGLNRTSSQGPEERSEYLKKVKSILNIVKEGQISLLNGQLECVRWMVSETEAIAELSCSKDFPSLIHYAGCYGQEKILLWLLQFMQEQGISLDEVDQDGNSAVHVASQHGYLGCIQTLVEYGANVTMQNHAGEKPSQSAERQGHTLCSRYLVVVETCMSLASQVVKLTKQLKEQTVERVTLQNQLQQFLEAQKSEGKSLPSSPSSPSSPASRKSQWKSPDADDDSVAKSKPGVQEGIQVLGSLSASSRARPKAKDEDSDKILRQLLGKEISENVCTQEKLSLEFQDAQASSRNSKKIPLEKRELKLARLRQLMQRSLSESDTDSNNSEDPKTTPVRKADRPRPQPIVESVESMDSAESLHLMIKKHTLASGGRRFPFSIKASKSLDGHSPSPTSESSEPDLESQYPGSGSIPPNQPSGDPQQPSPDSTAAQKVATSPKSALKSPSSKRRTSQNLKLRVTFEEPVVQMEQPSLELNGEKDKDKGRTLQRTSTSNESGDQLKRPFGAFRSIMETLSGNQNNNNNYQAANQLKTSTLPLTSLGRKTDAKGNPASSASKGKNKA
InterPro domains: - IPR032027: Synphilin-1, alpha-Synuclein-binding domain (domain) [452-495]
- IPR036770: Ankyrin repeat-containing domain superfamily (homologous_superfamily) [316-451]
- IPR002110: Ankyrin repeat (repeat) [334-428]
- IPR040133: Synphilin-1 (family) [335-858]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0019899 (enzyme binding), GO:0044389 (ubiquitin-like protein ligase binding), GO:0031625 (ubiquitin protein ligase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0065008 (regulation of biological quality), GO:0023051 (regulation of signaling), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0032879 (regulation of localization), GO:0008219 (cell death), GO:0050794 (regulation of cellular process), GO:1901615 (organic hydroxy compound metabolic process), GO:0001505 (regulation of neurotransmitter levels), GO:1903530 (regulation of secretion by cell), GO:0006725 (cellular aromatic compound metabolic process), GO:0099177 (regulation of trans-synaptic signaling), GO:0051049 (regulation of transport), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0051128 (regulation of cellular component organization), GO:0010646 (regulation of cell communication), GO:0044087 (regulation of cellular component biogenesis), GO:0051588 (regulation of neurotransmitter transport), GO:0009308 (amine metabolic process), GO:0051046 (regulation of secretion), GO:0046928 (regulation of neurotransmitter secretion), GO:0090083 (regulation of inclusion body assembly), GO:0018958 (phenol-containing compound metabolic process), GO:0050804 (modulation of chemical synaptic transmission), GO:0009712 (catechol-containing compound metabolic process), GO:0006576 (biogenic amine metabolic process), GO:0006584 (catecholamine metabolic process), GO:0042417 (dopamine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005829 (cytosol), GO:0098793 (presynapse), GO:0030054 (cell junction), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005654 (nucleoplasm), GO:0099080 (supramolecular complex), GO:0008021 (synaptic vesicle), GO:0036464 (cytoplasmic ribonucleoprotein granule), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0030133 (transport vesicle), GO:0043228 (non-membrane-bounded organelle), GO:0035770 (ribonucleoprotein granule), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0070382 (exocytic vesicle), GO:0031982 (vesicle), GO:0070013 (intracellular organelle lumen), GO:0097708 (intracellular vesicle), GO:0005634 (nucleus), GO:0031981 (nuclear lumen)