Protein: Dual specificity protein phosphatase (EC 3.1.3.16) (EC 3.1.3.48) (Q7TNL7)
Organism: Mus musculus (Mouse)
Function: Not known
Sequence: MESLSRSCLWLRQELSSPRPQLLLLDCRSRELYESARICGALSVALPSLMLRRLRRGSMSVRSLLPGPPLQPPPPAPVLLYDQGSSGQCHREAAEAEAKAEPKAEAEAEPKAEAEAEPKAEAENEAEAKAEAKAEAKAEAKAEAKAEAKAEAKAEAKAEAKAEAKEEWDADSVLGVLLQKLREEGYPAYYLQGGFSKFQAECPHLCETSFSGRAGSGLGSMSSPVPVVGLGGLCLSSDFSDAESEADRDTLSCGLDSENTTSPPAGLLPPFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNLFEKNGDFHYKQIPISDHWSQNLSQFFPEAIAFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLGGKRSGGRGSGGPESTVSDPPSFFTTPTSDGVFELDPT
InterPro domains: - IPR029021: Protein-tyrosine phosphatase-like (homologous_superfamily) [267-415]
- IPR000387: Tyrosine-specific protein phosphatases domain (domain) [335-395]
- IPR001763: Rhodanese-like domain (domain) [8-207]
- IPR020422: Dual specificity protein phosphatase domain (domain) [271-414]
- IPR036873: Rhodanese-like domain superfamily (homologous_superfamily) [1-212]
- IPR008343: Mitogen-activated protein (MAP) kinase phosphatase (family) [1-451]
- IPR000340: Dual specificity phosphatase, catalytic domain (domain) [279-410]
Interaction partners: - Mitogen-activated protein kinase 3
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 14
- Mitogen-activated protein kinase 11
- Stress-activated protein kinase JNK
- Mitogen-activated protein kinase 10
- Mitogen-activated protein kinase 9
- Mitogen-activated protein kinase 12
- Mitogen-activated protein kinase 13
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0004721 (phosphoprotein phosphatase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0008138 (protein tyrosine/serine/threonine phosphatase activity), GO:0016791 (phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0006793 (phosphorus metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0035556 (intracellular signal transduction), GO:0043170 (macromolecule metabolic process), GO:0033554 (cellular response to stress), GO:0036211 (protein modification process), GO:0006796 (phosphate-containing compound metabolic process), GO:0043412 (macromolecule modification), GO:0000165 (MAPK cascade), GO:0031098 (stress-activated protein kinase signaling cascade), GO:0016311 (dephosphorylation), GO:0070371 (ERK1 and ERK2 cascade), GO:0006470 (protein dephosphorylation), GO:0051403 (stress-activated MAPK cascade), GO:0007254 (JNK cascade)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)