Protein: ADAM metallopeptidase with thrombospondin type 1 motif 3 (G3X9D2)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Sequence: MVFLSLWLIAASLVEVRTSADGQAGTDEMVQIDLPTKRYREYELVTPVSTNLKGHYLSHILSANHKKRSPRDVSSNSEHLFFNVTAFGRDFHLRLKPNTHFIAPGAVVEWHETAPRPGNTTDPRNSHLHGSASEGSWRSEPLQTSCAYVGDIMDIPGTSVAISNCDGLAGMIKSDDEEYFIEPLERGKQMDEENGRIHVVYKRSAVEQPPRDVSEDVYHRESDLEGLDDLGTVYSNIGQQLNKTMRRRRHTGENDYNIEVLLGVDDSVVRFHGKEHVQNYLLTLMNIVNEIYHDESLGVHINVVLVRMIMLGYAKSISLIERGNPSRSLENVCRWACQQQKTDPNHAEHHDHAIFLTRQDFGPAGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDETAMGSVMAPLVQAAFHRYHWSRCSGQELKRYIHSYDCLLDDPFEHDWPKLPELPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAAGKWCYKGHCMWKNANQQKQDGNWGSWTKFGSCSRTCGTGVRFRTRQCNNPTPINGGQDCPGVNFEYQLCNTEECQKHFEDFRAQQCQQRNSHFDYQNTKHHWLPHEHPDSKKRCHLYCQSKETGDVAYMKQLVHDGTRCSYKDPYSICVRGECVKVGCDREIGSNKVEDKCGVCGGDNSHCRTVKGTFTRTPRKLGYLKMFDIPPGARHVLIQEDEASPHVLAIKNQATGHYILNGKGEEAKSRTFIDLGVEWDYNIEDDIETLHTDGPLHDPVIVLIIPQENDTRSSLTYKYIIHEDSVPTINSNNVIQEELDTFEWALKSWSQCSEPCGGGFQYTKYGCRRKSDSKMVHRSFCEVNKKPKPIRRMCNIQECTHPVWAADEWEHCSRSCGSSGNQLRTVRCLQPLQDGTNRSVHSKYCLGDRPESRRPCNRVPCPAQWKTGSWNECSVTCGEGTEVRQVLCRTGDHCDGEKPESVRPCQLPPCNDEPCLGDKSIFCQMEVLARYCSIPGYNKLCCESCSKRSGTLPPPYLQEAAEIHSDAIFGPSDLPRSLVMPTPFLPSSSGTRAEKKSLSSFSSMANPNADAAFRASSRASADFPRKRAHQAGRKTLESVPSSSSIKTDHLRPASPVAAAPSPAISDSIGASPQTRTPKKDDAKSVSRRHPTRSTASER
InterPro domains: - IPR001590: Peptidase M12B, ADAM/reprolysin (domain) [256-460]
- IPR041645: ADAMTS, cysteine-rich domain 2 (domain) [472-541]
- IPR024079: Metallopeptidase, catalytic domain superfamily (homologous_superfamily) [253-461]
- IPR013273: ADAMTS/ADAMTS-like (family) [560-712]
- IPR000884: Thrombospondin type-1 (TSP1) repeat (repeat) [551-1016]
- IPR010294: ADAMTS/ADAMTS-like, Spacer 1 (domain) [714-827]
- IPR050439: ADAMTS and ADAMTS-like (family) [280-1037]
- IPR010909: PLAC (domain) [1011-1054]
- IPR002870: Peptidase M12B, propeptide (domain) [43-152]
- IPR036383: Thrombospondin type-1 repeat superfamily (homologous_superfamily) [550-1019]
- IPR045371: ADAMTS/ADAMTS-like, cysteine-rich domain 3 (domain) [632-712]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0009790 (embryo development), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0051604 (protein maturation), GO:0006508 (proteolysis), GO:0010467 (gene expression), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development), GO:0016485 (protein processing), GO:0001701 (in utero embryonic development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)