Protein: Cyclohexane-1-carbonyl-CoA dehydrogenase (ChCoA dehydrogenase) (EC 1.3.8.11) (Q2LQP0)
Organism: Syntrophus aciditrophicus (strain SB)
Function: Mediates the conversion of cyclohexane-1-carbonyl-CoA into cyclohex-1-ene-1-carbonyl-CoA in biosynthesis of cyclohexane-1-carboxylate, a by-product produced during fermentation of benzoate and crotonate to acetate.
Sequence: MYINTETEDLKTAIDAIRKAVKDRIAPLAAEVDDSGVIKPEIYDLLWDLGLMTVTYPPEYGGSETNPGTLLCIGCEEIAKACASTALLLIIQAVGSFPLMHGGRKELLDRIAPRIVNNRELAGYLVSEPGAGSDVKAIRTKAVKDGNDWVINGTKCWATNGPIASFYSCLCRTKDDKGVQGYSFFLVERNTPGLSVGKIEHKMGMRGSQTSEVILEDVRVPAENLLGELNNGFKLAMKDFDMSRPAIAAQALGISEGAFAQMETYSRERYTFGKPLCEHGMITQIIADSAALIEAGRGLIYQAADLYDKGKKNTKLASMAKFFMGDAAVKITTDAIQVFGGYGYTHDYPVERMFRDAKLTQIFEGANQIQRIVVAREIRDEQSK
InterPro domains: - IPR037069: Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily (homologous_superfamily) [3-111]
- IPR054991: Cyclohexane-1-carbonyl-CoA dehydrogenase (family) [3-383]
- IPR036250: Acyl-CoA dehydrogenase-like, C-terminal (homologous_superfamily) [228-380]
- IPR013786: Acyl-CoA dehydrogenase/oxidase, N-terminal (domain) [7-117]
- IPR006091: Acyl-CoA oxidase/dehydrogenase, middle domain (domain) [124-218]
- IPR009100: Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily (homologous_superfamily) [6-237]
- IPR006089: Acyl-CoA dehydrogenase, conserved site (conserved_site) [337-356]
- IPR046373: Acyl-CoA oxidase/dehydrogenase, middle domain superfamily (homologous_superfamily) [123-235]
- IPR009075: Acyl-CoA dehydrogenase/oxidase, C-terminal (domain) [230-378]
Interaction partners: - Cyclohex-1-ene-1-carbonyl-CoA dehydrogenase
- Electron transfer flavoprotein subunit alpha
- Electron transfer flavoprotein subunit beta
- 3-hydroxyacyl-CoA dehydrogenase
- Acetyl-CoA acetyltransferase
- Pyruvate:ferredoxin oxidoreductase
- Enoyl-CoA hydratase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0016491 (oxidoreductase activity), GO:0043168 (anion binding), GO:0000166 (nucleotide binding), GO:1901265 (nucleoside phosphate binding), GO:0016627 (oxidoreductase activity, acting on the CH-CH group of donors), GO:0016628 (oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor), GO:0050660 (flavin adenine dinucleotide binding), GO:0071949 (FAD binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009056 (catabolic process), GO:0044237 (cellular metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:1901575 (organic substance catabolic process), GO:0044255 (cellular lipid metabolic process), GO:0006629 (lipid metabolic process), GO:0044248 (cellular catabolic process), GO:0006720 (isoprenoid metabolic process), GO:0016042 (lipid catabolic process), GO:0044242 (cellular lipid catabolic process), GO:0008300 (isoprenoid catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)