Protein: unspecific monooxygenase (EC 1.14.14.1) (S5RV20)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Endoplasmic reticulum membrane {ECO:0000256|ARBA:ARBA00004586}. Microsome membrane {ECO:0000256|ARBA:ARBA00004524}.
Sequence: MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICNNFSPIIDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMDMNNPQDFIDCFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVPPFYQLCFIPV
InterPro domains: - IPR036396: Cytochrome P450 superfamily (homologous_superfamily) [19-490]
- IPR017972: Cytochrome P450, conserved site (conserved_site) [428-437]
- IPR001128: Cytochrome P450 (family) [30-487]
- IPR002401: Cytochrome P450, E-class, group I (family) [58-458]
- IPR050182: Cytochrome P450 family 2 (family) [5-475]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0004497 (monooxygenase activity), GO:0016725 (oxidoreductase activity, acting on CH or CH2 groups), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen), GO:0008391 (arachidonic acid monooxygenase activity), GO:0008395 (steroid hydroxylase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0065008 (regulation of biological quality), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0051716 (cellular response to stimulus), GO:0042445 (hormone metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0070988 (demethylation), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0120254 (olefinic compound metabolic process), GO:0009410 (response to xenobiotic stimulus), GO:0070887 (cellular response to chemical stimulus), GO:0006082 (organic acid metabolic process), GO:0044248 (cellular catabolic process), GO:0008210 (estrogen metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006805 (xenobiotic metabolic process), GO:0043603 (amide metabolic process), GO:0010817 (regulation of hormone levels), GO:0071941 (nitrogen cycle metabolic process), GO:0019627 (urea metabolic process), GO:0019369 (arachidonic acid metabolic process), GO:0006631 (fatty acid metabolic process), GO:0071466 (cellular response to xenobiotic stimulus), GO:0006720 (isoprenoid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0016053 (organic acid biosynthetic process), GO:0008202 (steroid metabolic process), GO:0042178 (xenobiotic catabolic process), GO:0008610 (lipid biosynthetic process), GO:0006633 (fatty acid biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0033559 (unsaturated fatty acid metabolic process), GO:0001676 (long-chain fatty acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process), GO:0006721 (terpenoid metabolic process), GO:0072330 (monocarboxylic acid biosynthetic process), GO:0042759 (long-chain fatty acid biosynthetic process), GO:0032787 (monocarboxylic acid metabolic process), GO:0016098 (monoterpenoid metabolic process), GO:0006690 (icosanoid metabolic process), GO:0046456 (icosanoid biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0031984 (organelle subcompartment), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0031090 (organelle membrane), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0098827 (endoplasmic reticulum subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0005789 (endoplasmic reticulum membrane)