wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: High-energy light unresponsive protein 1 (Q17990)
Organism: Caenorhabditis elegans
Function: Photoreceptor for short wavelength (UV) light that mediates UV-light-induced avoidance behavior. Directly senses and absorbs both UV-A and UV-B light with very high efficiency. Absorption of UV-B but not UV-A light shows resistance to photobleaching. In contrast to other photoreceptors, does not use a prosthetic chromophore to capture photons and only depends on its protein conformation. Might have a role in response to white light exposure.
Subcellular location: Cell membrane {ECO:0000269|PubMed:27863243}; Multi-pass membrane protein {ECO:0000255}.
Sequence: MPPPSSHSNIFHSTFKHTVKETMANAKKTMIAKILSSRNKWAICDRTLYPIYYLLLILGLNQSIRPNNSLLFRIYSWLVFCLLLFTTLRKFNQVGVRPNGTRENLQEFFANPRSMITLCNALIMLSGLLASLQLYTLGAKRLKPLKILCQFSLNVRTKQAERRQFMINTFLAVFSGLLALTMAATYAMSKWGYILYIVGTPNLDTETIFCVLLDSYALFVSRAAISALAILFYQHCSVIRRSIKHLINEMVPAEQDECPLPESSLQKIHDCQISYQRIFNGKAVIEEYYSFVLFYSYGVCIPIFCFLMFVGMSAQSICWSEVVSIVIWIVNAILVLLLFSLPAFMINEDGDRLVASSFRMYHETFHEERDLTVLSQMTFFTFQIHSTKLTLSACNYFYMDRSILLSLFSAILTYFLILWEFDIKNNQSLQNIANHTIHT
InterPro domains: - IPR013604: 7TM chemosensory receptor (family) [48-425]
Interaction partners: - G protein-coupled receptor
- Probable G-protein coupled receptor egl-47
- Gustatory receptor
- LITAF domain-containing protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0008527 (taste receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0007610 (behavior), GO:0007631 (feeding behavior), GO:0042755 (eating behavior), GO:0043050 (pharyngeal pumping)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0031252 (cell leading edge), GO:0031256 (leading edge membrane), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0036477 (somatodendritic compartment), GO:0071944 (cell periphery), GO:0098590 (plasma membrane region), GO:0120025 (plasma membrane bounded cell projection), GO:0097447 (dendritic tree), GO:0032589 (neuron projection membrane), GO:0005886 (plasma membrane), GO:0043005 (neuron projection), GO:0032590 (dendrite membrane), GO:0031253 (cell projection membrane), GO:0030425 (dendrite)
Protein: D-lactate dehydrogenase (cytochrome) (EC 1.1.2.4) (A0A0G2K1W9)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
Sequence: RAMLLRVATQRLSPWRGYCSRGSQGGLSQDFVEALKAVVGSPHVSTASAVRQHHGHDESMHRCRPPDAVVWPQNVDQVSRLASLCYNQGVPIIPFGTGTGVEGGVCAVQGGVCISLTHMDQIMELNTEDFSVVVEPGVTRKALNTHLRNSGLWFPVDPGADASLCGMAATGASGTNAVRYGTMRDNVINLEVVLPDGRLLHTAGRGRHYRKSAAGYNLTGLFVGSEGTLGIITSATLRLHPAPEATVAATCAFPSVQAAVDSTVQILQAAVPVARIEFLDEVMMDACNRHSKLNCPVAPTLFLEFHGSQQALAEQLQRTEAITQDNGGSHFSWAKEAEKRNELWAARHNAWYAALALRPGSKAYSTDVCVPISRLPEILVETKEELKASKLTGVIVGHVGDGNFHCILLVNPDDVEEQRRVKAFAENLGRRALALHGTCTGEHGIGLGKRQLLQEEVGPVGVETMRQLKDTLDPRGLMNPGKVL
InterPro domains: - IPR016167: FAD-binding, type PCMH, subdomain 1 (homologous_superfamily) [6-119]
- IPR006094: FAD linked oxidase, N-terminal (domain) [66-202]
- IPR016166: FAD-binding domain, PCMH-type (domain) [62-242]
- IPR016169: FAD-binding, type PCMH, subdomain 2 (homologous_superfamily) [121-243]
- IPR004113: FAD-binding oxidoreductase/transferase, type 4, C-terminal (domain) [243-483]
- IPR016171: Vanillyl-alcohol oxidase, C-terminal subdomain 2 (homologous_superfamily) [444-484]
- IPR036318: FAD-binding, type PCMH-like superfamily (homologous_superfamily) [28-243]
- IPR016164: FAD-linked oxidase-like, C-terminal (homologous_superfamily) [246-484]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0009056 (catabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:0044282 (small molecule catabolic process), GO:1901575 (organic substance catabolic process), GO:0006082 (organic acid metabolic process), GO:0044248 (cellular catabolic process), GO:0006089 (lactate metabolic process), GO:0016054 (organic acid catabolic process), GO:1901616 (organic hydroxy compound catabolic process), GO:0043436 (oxoacid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0046395 (carboxylic acid catabolic process), GO:0072329 (monocarboxylic acid catabolic process), GO:0032787 (monocarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005740 (mitochondrial envelope), GO:0019866 (organelle inner membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031966 (mitochondrial membrane), GO:0005743 (mitochondrial inner membrane)
Protein: Homeobox protein Hox-B3 (Homeobox protein Hox-2.7) (Homeobox protein Hox-2G) (P14651)
Organism: Homo sapiens (Human)
Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular location: Nucleus.
Sequence: MQKATYYDNAAAALFGGYSSYPGSNGFGFDVPPQPPFQAATHLEGDYQRSACSLQSLGNAAPHAKSKELNGSCMRPGLAPEPLSAPPGSPPPSAAPTSATSNSSNGGGPSKSGPPKCGPGTNSTLTKQIFPWMKESRQTSKLKNNSPGTAEGCGGGGGGGGGGGSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAGSPPQPMQSTAGFMNALHSMTPSYESPSPPAFGKAHQNAYALPSNYQPPLKGCGAPQKYPPTPAPEYEPHVLQANGGAYGTPTMQGSPVYVGGGGYADPLPPPAGPSLYGLNHLSHHPSGNLDYNGAPPMAPSQHHGPCEPHPTYTDLSSHHAPPPQGRIQEAPKLTHL
InterPro domains: - IPR001356: Homeodomain (domain) [186-250]
- IPR020479: Homeodomain, metazoa (domain) [210-244]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [175-248]
- IPR017970: Homeobox, conserved site (conserved_site) [221-244]
- IPR001827: Homeobox protein, antennapedia type, conserved site (conserved_site) [129-134]
- IPR025281: Domain of unknown function DUF4074 (domain) [366-429]
Interaction partners: - Homeobox protein Hox-B4
- Homeobox protein Hox-B5
- Homeobox protein Hox-B6
- Homeobox protein Meis1
- Homeobox protein Hox-B9
- Pre-B-cell leukemia transcription factor 1
- Homeobox protein Hox-B8
- Histone-lysine N-methyltransferase EZH2
- Homeobox protein Hox-B2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0001501 (skeletal system development), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Flavohemoprotein (EC 1.14.12.17) (Flavohemoglobin) (Hemoglobin-like protein) (Nitric oxide dioxygenase) (NO oxygenase) (NOD) (Q59MV9)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Nitric oxide dioxygenase involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the fungus from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress. Plays a role in virulence since nitric oxide is generated by macrophages of the host immune system.
Subcellular location: Cytoplasm {ECO:0000250}.
Sequence: MTVEYETKQLTPAQIKIILDTVPILEEAGETLTQKFYQRMIGNYDEVKPFFNTTDQKLLRQPKILAFALLNYAKNIEDLTPLTDFVKQIVVKHIGLQVLPEHYPIVGTCLIQTMVELLPPEIANKDFLEAWTIAYGNLAKLLIDLEAAEYAKQPWRWFKDFKVTRIVQECKDVKSVYFTPVDKDLLPLPKPERGQYLCFRWKLPGEEFEISREYSVSEFPKENEYRISVRHVPGGKISGYIHNNLKVGDILKVAPPAGNFVYDPATDKELIFVAGGIGITPLLSMIERALEEGKNVKLLYSNRSAETRAFGNLFKEYKSKFGDKFQAIEYFSEDNNTDDKIVIDKAFNRKLTTDDLDFIAPEHDVYLVGPREFMKDIKEHLGKKNVPVKLEYFGPYDP
InterPro domains: - IPR012292: Globin/Protoglobin (homologous_superfamily) [9-153]
- IPR017938: Riboflavin synthase-like beta-barrel (homologous_superfamily) [155-260]
- IPR001433: Oxidoreductase FAD/NAD(P)-binding (domain) [272-378]
- IPR017927: FAD-binding domain, ferredoxin reductase-type (domain) [156-263]
- IPR000971: Globin (domain) [9-147]
- IPR008333: Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain (domain) [162-262]
- IPR039261: Ferredoxin-NADP reductase (FNR), nucleotide-binding domain (homologous_superfamily) [251-397]
- IPR009050: Globin-like superfamily (homologous_superfamily) [10-158]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0051213 (dioxygenase activity), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0006979 (response to oxidative stress), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0034599 (cellular response to oxidative stress), GO:0062197 (cellular response to chemical stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0009986 (cell surface), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Large ribosomal subunit protein P2 (60S acidic ribosomal protein P2) (A7E2K4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Sequence: MRYVAAYLLAALGGKDSPSTGDIKKILESVGIEADDVRMSKVVAELNGKNVEEVIAQGFSKLASVPSGGAVAVSSAAAPSSGGSAAAPAAEEKKEEKKEESEESDDDMGFGLFD
InterPro domains: - IPR044076: Large ribosomal subunit protein P2, eukaryotes (family) [1-114]
- IPR027534: Large ribosomal subunit protein P1/P2 (family) [2-114]
- IPR038716: Large ribosomal subunit protein P1/P2, N-terminal domain (homologous_superfamily) [1-60]
Interaction partners: - FAU ubiquitin-like and ribosomal protein S30 fusion b
- FAU ubiquitin-like and ribosomal protein S30 fusion a ubiquitously expressed
- Large ribosomal subunit protein P1
- Large ribosomal subunit protein uL10
- Small ribosomal subunit protein eS25
- Small ribosomal subunit protein uS2
- 40S ribosomal protein S15
- Large ribosomal subunit protein eL19
- Ribosomal protein L3
- Small ribosomal subunit protein eS19
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0042592 (homeostatic process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0048871 (multicellular organismal-level homeostasis), GO:0002262 (myeloid cell homeostasis), GO:0034101 (erythrocyte homeostasis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048872 (homeostasis of number of cells), GO:0030097 (hemopoiesis), GO:0030218 (erythrocyte differentiation), GO:0030099 (myeloid cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0022626 (cytosolic ribosome), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005840 (ribosome)
Protein: 5'-nucleotidase, cytosolic IA (A0A8I5ZYY7)
Organism: Rattus norvegicus (Rat)
Function: Not known
Sequence: MTISRPRRNPNRPWLILVTEIVSCGLPVSGVWSVPTEAPEMVDSQPKPQNAVTIAVSSRALFRMDEEQRIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNKQLRELYPDSEDIFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADAEKVREAIDEGIAAATIFSPSKDVVVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQNPRREKQSLGAQ
InterPro domains: - IPR010394: 5-nucleotidase (family) [39-360]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0016791 (phosphatase activity), GO:0008252 (nucleotidase activity), GO:0008253 (5'-nucleotidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:1901657 (glycosyl compound metabolic process), GO:0072521 (purine-containing compound metabolic process), GO:0009116 (nucleoside metabolic process), GO:0009119 (ribonucleoside metabolic process), GO:0042278 (purine nucleoside metabolic process), GO:0046128 (purine ribonucleoside metabolic process), GO:0046085 (adenosine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Membrane associated ring-CH-type finger 1 (D6REN1)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Cytoplasmic vesicle membrane {ECO:0000256|ARBA:ARBA00004439}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004439}. Early endosome membrane {ECO:0000256|ARBA:ARBA00004520}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004520}. Lysosome membrane {ECO:0000256|ARBA:ARBA00004155}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004155}.
Sequence: MLGWCEAIARNPHRIPNNTRTPEISGDLADASQTSTLNEKSPGRSASRSSNISKASSPTTGTAPRSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGTLRFVHQSCLHQWIKSSDTRCCELCKYDFIMETKLKPLRK
InterPro domains: - IPR011016: Zinc finger, RING-CH-type (domain) [72-133]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [65-140]
- IPR001841: Zinc finger, RING-type (domain) [80-127]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity), GO:0061659 (ubiquitin-like protein ligase activity), GO:0061630 (ubiquitin protein ligase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044248 (cellular catabolic process), GO:0019538 (protein metabolic process), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:0009057 (macromolecule catabolic process), GO:0043412 (macromolecule modification), GO:1901565 (organonitrogen compound catabolic process), GO:0006508 (proteolysis), GO:0044265 (cellular macromolecule catabolic process), GO:0030163 (protein catabolic process), GO:0070647 (protein modification by small protein conjugation or removal), GO:0043632 (modification-dependent macromolecule catabolic process), GO:0051603 (proteolysis involved in protein catabolic process), GO:0032446 (protein modification by small protein conjugation), GO:0019941 (modification-dependent protein catabolic process), GO:0016567 (protein ubiquitination), GO:0006511 (ubiquitin-dependent protein catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Palmitoyltransferase (EC 2.3.1.225) (Q0IGS7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MMILRSWDRVKPRSISDFACFLLVAVFVPVTYIFHVTIVMPELFAIGGIWYTLLWLASLFLIFNITSNMLACMLVDTSIRKELLKPPLDAAQLARWHSCQDCQTLVPPRSWHCEVCNVCVLKRDHHCRFTCCCIGHHNYRYFFYYLVYMIIGSLAAAIMESIYLWHLHLDIYWRWSTLFTIFAPVVSLMLSPSWESFYLVIYDLTLLGFAISSLLLVFHWSIFKSGSVTRERGTRKYDRGLRGNLEMVLGKRMHLTWLSPFLRSDLPHDGMNWEPIAAFSPKEE
InterPro domains: - IPR001594: Palmitoyltransferase, DHHC domain (domain) [96-231]
- IPR039859: Palmitoyltransferase PFA4/ZDHHC16/ZDHHC20/ERF2-like (family) [19-276]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016746 (acyltransferase activity), GO:0019707 (protein-cysteine S-acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0019706 (protein-cysteine S-palmitoyltransferase activity), GO:0016417 (S-acyltransferase activity), GO:0016409 (palmitoyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009615 (response to virus), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0140546 (defense response to symbiont), GO:0051607 (defense response to virus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: SPX domain-containing protein 3 (Protein SPX DOMAIN GENE 3) (OsSPX3) (Q7XEY9)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Functional repressor of PHR2. Involved in maintaining cellular Pi homeostasis when plants are exposed to an external change in Pi. Negatively regulates root-to-shoot Pi translocation redundantly with SPX3. Down-regulates the non-coding RNA IPS1 (At3g09922) and suppresses the responses of miR399 and PHO2 to Pi-starvation.
Subcellular location: Nucleus {ECO:0000269|PubMed:24368504}. Cytoplasm {ECO:0000269|PubMed:19566645, ECO:0000269|PubMed:24368504}.
Sequence: MKFGKRLKKQVEESLPEWRDKFLAYKRLKKLVRLVSSSSGDVGGGGGGEAEFVRLLDGEVDRINAFFLEQEEEFVIRQRELQETVEKVAGGGGGGRRPAAAEMRRVRKEIVDLHGEMVLLLNYSAVNYTGLAKILKKYDKRTGRLLRLPFIEKVLRQPFFTTELISRLVRDCEATMEAIFTSSVATTAMAGDRRTWKGCSGDAGMAPMADQQGIFRNTVAALATMKELRSGSSTYGRFSLPPMAAPASPESDVLQSIRSDPHLKENGRIPSLQFFYA
InterPro domains: - IPR031142: SPX domain-containing protein (family) [1-245]
- IPR004331: SPX domain (domain) [1-154]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0009266 (response to temperature stimulus), GO:0009409 (response to cold), GO:0033554 (cellular response to stress), GO:0070417 (cellular response to cold)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: UPF0381 protein YfcZ (P0AD33)
Organism: Escherichia coli (strain K12)
Function: Not known
Sequence: MSKCSADETPVCCCMDVGTIMDNSDCTASYSRVFANRAEAEQTLAALTEKARSVESEPCKITPTFTEESDGVRLDIDFTFACEAEMLIFQLGLR
InterPro domains: - IPR035571: UPF0234-like, C-terminal (homologous_superfamily) [2-94]
- IPR005272: Protein of unknown function DUF406 (family) [1-94]
Interaction partners: - NADP-dependent 3-hydroxy acid dehydrogenase YdfG
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0006950 (response to stress), GO:0009628 (response to abiotic stimulus), GO:0009408 (response to heat), GO:0009266 (response to temperature stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)