Protein: FRAS1-related extracellular matrix protein 2a precursor (Frem2a) (B6IDE6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Sequence: MELHRFLLLLLSLTGSSMSALETHGLSYASKPELSEDAILVANNGIHVPFGRSVYIDPINDLVIELQPGDRCTITVLDNDPLSQRPGHVSPKKFPCEFGPNDVRYSHFGSRSPAGDRVKLQLRYDTQTETIIIPFMLEVEVVFTQLEVVTKNMPLVVDKLHGTSNPINKKILDFTYEKDSEQCEVTSLAASSVLPKYGKVVDDKKLDKMMSCELFLKSNIRYEHTSSHKSPNKDYIPMVVELRNKENNLLKQEFFHVMIRIKEGEENTPPRPSFVAMMMMEVDQFVMTALTPDMLAAEDTESNSDDLIFNITSPLSIEEGYIVSTDDRNLPITSFYQKDLKDLKIAYKPPSLDSDTERIFQIEFEVIDPDGGISDPFAFMIVVKPMNTLAPIVTKNSGQLLYEGQSRSLFTQNNLEISDEDNLDSVRITVVDGLRHGVLTVLGSNRKYFSPADLEVGIVVYQHDGSDTYSDNIIFRMTDGKNEVEFLFPITIVPTDDEPPIINANTGLILFKNQMVPISQLMLSAADIDSEDSIIKFTIEPPFSAIGEVVLRQSEAPEDPSSWKFNADDGVYEKVVTEWLQKDITNEKLFYRHTGPHITETVTDQFVFKVKDDADPPNQSSENNFIIKILPIDDIPPVLFPGTTLQMTVHEYQLTHLSKNVLRYTDLDSEDRDLKYTITQAPTDMDENNPVKFGSIVLTDSPDTDVTEFTQAQINHHKISYNPPDLELGIIPHVVQFHFTVEDTAGNGADGVFTIFLQPVNNKPPQITNSGFTVLERGVHVITSAELDANDLDTDIKLISFTLSQTPLHGHLQHTFTDLKKGSHFNLMDISDGQVSYVHNGDETTSDSFKLDVSDGVHVVTITVKVTVKLIDDETPTLSLTKGTFGSRLDVLENGATEITPNVIQGKDEDTDDLQLTFIVEEAPKFGEILVNGVSSSRFTQADIISGLVVYAHTSGEIGLTSIEDFFSLTLSDMSDEWNVGGNRVHGVRVHVTILPVDNQTPLVTVGPTFNVFEADKNIIGSHQIKVEDADTPNEDILCTIIVQPTSGYVENISPAPGSEKSRAGTAVSAFTISDVNEGHIYYVQSIHKGVEPVEDRFTFRCSDGVNFSERQFFPIVIIPTNDEKPEIFMREVVVMEGMNVIIDTPLLNGVDADVPAQELMFIITKLPNHGFILNQLASGSVPVTNFTLEQIKEASSIIYEHDDSETTEDKFDVLLTDGKHKAEGTVMIMIIPVDDETPRLAINDGLEIEIGETKEINAKVLKATDLDSDDESLTFIIRYGPAQGLLYRKSAGSVEKRSAGSTENITVGMNFTQNEVNRGLILYTHNGQEGMRDLVKFDVTDGINPLIDRYFYITVGSIDMVFPDVISKGVSLKEGGKVTLTTNLLSTSDLNSPDENLVFTITRAPVRGHLESTDTPGMPIVSFTQLQLAGSKIYYIHTADDEVKMDSFEFEVTDGYNPVFRTFRVSIVDVDNKKPVLTIHDLLVTEGQTKLITPFELTVEDQDTAEHLLKFKVSQLPIHGKLLFNNSQPLTSFTKQDLNENMISYKHDGTESKKDSFSFTVTDGTHSDFFVFPDTIFETQRPQTMKINIVSVDNGVPQIEVNKGAPTLKVLFAGHLGYQMTSKVLKAVDRDSNPEALIFHITTQPEHGYLISLDRGTENDSINTFTQADINDLKICYILKDENNATSDVFSFTVEDNGGNKLKNQPFHLNWSWISLEKPNYVVDEHDKVLEVTLRRRGFLGETSFVGIGTLDGSAEKEKDFLGKSQKQVQFNPGQTTASWKVRVLSDGKYEQSETFQIVLTEPVMGVLEAPAVATVEIVDPGDESMVFFPQAGFAVEEDIGELLVPVRRTGDVSQELMVVCHTQQDSATGTVPTSVLSYSDYISRPEEQVSILRFDKDETEKHCRVVIIDDSLYESEESFNVTLSMPIGGRLGPEYPTVNIRILPDQDDAPVFYFGSQEYHVDESDGHVEVRVWRTGTDLSKTATVTVRSRKTDPVSAEAGVDYVGISRNLDFAPGVSMQTVRVTVLDDLGQPVLEGTERFELVLRMPSNGILGEPAKVTVFINDSISDLPKVQFKQAVVTVEESEGHVTVMVHRSGDIKHKSSVRCYTRQGSAQVVYDFEERPNTDASIVTFLPGEVDKPCVLKLVDDSIHEEEEELRLVLGNAKSDSPYGASIGNQNETLIKIKDNADKSIIKFAETKFSVSEPKESGQVTLVKIPIRRTGDSSKVSLVRVHTKDGSAISGEDYHPISLDVEFKAEEIEHVVEVEVLFDGIREMREAFTVHLKPDENMIAEIQMTKAIVYIEETNSMADVTFPSLPHIVSLLHYDNIRTSKQSAHPPAGYPVVCVTACNPKYPDYDKTGSICISERINNTLTRYRWLISAPSGPDGVTSPMREADFDTFFTSSKMITLDSIYFQAGSRVQCAARAVNSNGDEGLELSSPIVSISMEEGMCQPRKLGTVGAEPFSAKLRYTGAEDLEYANLIKLTVTMPHIDGMLPVVSTRALSNFDLTLSPDGTRVGNHRCSNLLDFNEVSTRHGFLTKATRNIQSVGETLPYQYSPVLRGQGTLRFYRNLNLEACLWEFVSYYDMSELLTDCGGTIGTDGQVLNLVQSYVTLRVPLHVSYVFHSPVGAGGWQHFDLHSELRLTFVYDTAILWKDGVGSQTQADLQGNLGALYPTSMRINEQGRLVVNFRTEARFRGLFVVGHPASTVSTVMSADHPGLTFNLTLVRTEPTYSQPVQQWMFISDFAVRDYSGTYTVSLIPCTAALNVEFTVPPVCNPREAITFDLDIRFQQVSDPVAVEFSLNTQMFLLSKKVLWLSDGSMGFGQESDAAFSEGDVIYGRVMVDPVQNLGDSFYCNIEKVYLCTGADGYVPKYNPSKSEFGCLADSPSLLYQFKIIDKAQPETQARSFGNVDFNALLAVDDPSALSLVKQPGSDGFRLHSTPLFQVAVGREWFIHTIYTVRSKDNAKRGIGKRSVEQHLITSGDLKESRRRSRRSNRDVPTLAEQIGPENNRGTNIMHIALDRSRRTASEEELFAEGLSPRGLSGRQAEEEAVTVAGALVGLLLTVLVFVALALVVRSRRTPAKKAPRVSPSLQPVIVRSSLDNGDSSEV
InterPro domains: - IPR038081: CalX-like domain superfamily (homologous_superfamily) [1700-2324]
- IPR039005: CSPG repeat (repeat) [271-1696]
- IPR003644: Na-Ca exchanger/integrin-beta4 (domain) [1703-2305]
- IPR045658: FRAS1-related extracellular matrix protein, N-terminal domain (domain) [39-240]
- IPR051561: FRAS1-related extracellular matrix (family) [9-2955]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048736 (appendage development), GO:0035107 (appendage morphogenesis), GO:0033333 (fin development), GO:0033334 (fin morphogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix)