Protein: Fer-1 like family member 6 (E0CZ42)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
Sequence: MFGLKLKKKKKDKAEKGLVLTNKGAQDGNESEIPQKGPSHQEGPEDLTKDDAFLAPGPSAPSKRRAKLLTKIHDGEIKSQNYQITVTITEARQLVGENIDPVVTIEIGDDKKQSTVKEGTNSPFYNEYFVFDFIGPQVHLFDKIIKISVLHHKLIGSILIGSFRVDVGTVYNQPGHQFCDKWALLTDPGDIRTGTKGYLKCDISVTGKGDILKTNPKTSDAEEQIEKNLLIPQGFPSERPWARFYVRLYRAEGLPKMNSSIMANVTKAFVGDSKDLVDPFVEVSFAGQTGRTSVQKNCADPVWHEQVVFKEMFPPLCRRVKIQVWDEGSMNDVALATHFIDLKKISNEQDGDKGFLPTFGPAWINLYGSPRNHSLMDDYQELNEGFGEGVSFRGRILVEIAVEILSGGAQESKFSKALKELKLSSKDKDSKSSKGSSKDKADKADDSKAQQTTDKTNSTEVEVESFAVPPEIIPEKYEDFLLFGAFFEATMIDRKIGDKPISFEVSVGNFGNLIDGGSHHGSKKKSTELTEEDVLPLLHEGEKDVAQDSAISMASTTHPEKPLVTDGNRNYNYLPFGAKKPCVSFISSWGDQTFRLHWSNMLEKMADLLEEGIEEVRELVKVSQEAPEEKMKTALRDFITQSRVFISEAEKKPKTLNQTALDKKRLTLCWQELKAMADEAEGVIRQQKKKLSLDEMIREAQNFVEKIHFLVDEPQHTIPDVFIWMLSNNKRVAYARIAAKDLLYSPIEEQMGKHCGKIKTHFLKLPGKRPPGWTVQAKVDIYLWLGSTRYSNTILDNLPVGYEAEMPPKSSGTHHPPSALLYQAQHVFQLRAHMYQARGLIAADSNGLSDPFAKVTFLSQCQTTKIISQTLSPTWNQMLLFNELVLHGEEKELLESPPHVVVELYDSDAVGKPEYLGATVAAPVVTLADQDYEPPKLSYHPIFCGNLSGGDLLAVFELLQVPPSGLQGLPPTGPPDITQIYPVPSNIRPVLSKYRVEVLFWGVREMKKVQLLSVDRPQVLIECGGGGVKSCVIQSYKNNPNFSVQAEAFEVELPENELLHPPLSICVVDWRAFGRSTLVGTYTINCLKQFLCKPRETFALTSQTDGDGARPAISDSLAATESSNLLSSSQDLPADHVYVDVEPPPTMLPDSAQAQTATLVDIPDSSPMLETEHKPVAQGPPKDGHGKDPRKPSRRSTKRRRRTIADESAENVIDWWSKYYASVKRAQKEKENNHKEKRATEAKPDEVVLDMEDGPKRKKDKMLKKKLKDDGNDAIPNLAALKIYDGDLESEFNNFEDWVKTFELFRGKSTEEDHGLDGDRVIGKFKGSFCIYKSPEDSTSEDSGQLRIQQGIPPNHPVQVLIRVYIVAAFNLSPADPDGKSDPYIVLRLGKTEIKDRDKYIPKQLNPVFGRSFEIQATFPKESLLSVLIYDHDMIGSDDLIGETKIDLENRFYSKHRAICGLQSQYEIEGYNAWRDTSKPTEILTKLCKDNKLDGPYFRPGKIQIGKKVFSGKTVFNEEDSEEMVESYEHLALKVLHSWEDIPEAGWRLVPEHIETRPLYHKDKPGMEQGRLQMWVDMFPKDTPQLGPPVDISPRKPKGYELRVTIWNTEDVILEDENIFTGQKSSDIYVKGWIKGLEDDRQETDVHYNSLTGEGNFNWRFLFPFQYLPAEKQMVISKRENIFSLEKMECKTPAVLVLQVWDFERLSSDDFLGSLEMNLNSFPRAAKSAKACDLSKFENAVQENKISIFQQKRVRGWWPFAKSKELTGKVEAEFHLVTAEEAEKNPVGKARKEPEPLAKPNRPDTSFSWFVSPFKCLYHLIWKNYKKYIIIAFILIILIVFLVLFIYTLPGAISRRIVVGGS
InterPro domains: - IPR037720: Ferlin, second C2 domain (domain) [79-188]
- IPR035892: C2 domain superfamily (homologous_superfamily) [67-1734]
- IPR055072: Ferlin, dsRNA-binding domain-like domain (domain) [1453-1540]
- IPR037721: Ferlin family (family) [76-1858]
- IPR000008: C2 domain (domain) [64-1733]
- IPR037724: Ferlin, fifth C2 domain (domain) [1361-1484]
- IPR037723: Ferlin, fourth C2 domain (domain) [828-961]
- IPR012561: Ferlin B-domain (domain) [714-787]
- IPR012968: FerIin domain (domain) [165-235]
- IPR037722: Ferlin, third C2 domain (domain) [243-394]
- IPR032362: Ferlin, C-terminal domain (domain) [1766-1857]
- IPR037725: Ferlin, sixth C2 domain (domain) [1601-1734]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0005509 (calcium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0007267 (cell-cell signaling), GO:0051641 (cellular localization), GO:0065008 (regulation of biological quality), GO:0140029 (exocytic process), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0140352 (export from cell), GO:0007154 (cell communication), GO:0099536 (synaptic signaling), GO:0016082 (synaptic vesicle priming), GO:0044085 (cellular component biogenesis), GO:0006810 (transport), GO:0051649 (establishment of localization in cell), GO:0032940 (secretion by cell), GO:0016043 (cellular component organization), GO:0001505 (regulation of neurotransmitter levels), GO:0023061 (signal release), GO:0006836 (neurotransmitter transport), GO:0099504 (synaptic vesicle cycle), GO:0006887 (exocytosis), GO:0099643 (signal release from synapse), GO:0099537 (trans-synaptic signaling), GO:0046903 (secretion), GO:0007269 (neurotransmitter secretion), GO:0016192 (vesicle-mediated transport), GO:0043933 (protein-containing complex organization), GO:0016079 (synaptic vesicle exocytosis), GO:0022607 (cellular component assembly), GO:0098916 (anterograde trans-synaptic signaling), GO:0099003 (vesicle-mediated transport in synapse), GO:0065003 (protein-containing complex assembly), GO:0045055 (regulated exocytosis), GO:0007268 (chemical synaptic transmission)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)