Protein: Pyruvate decarboxylase (EC 4.1.1.1) (Q6FJA3)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Function: Not known
Sequence: MSEITLGRYLFERLNQVDVKTIFGLPGDFNLSLLDKIYEVEGMRWAGNANELNAAYAADGYARIKGMSCIITTFGVGELSALNGIAGSYAEHVGVLHVVGVPSISSQAKQLLLHHTLGNGDFTVFHRMSANISETTAMVTDIATAPAEIDRCIRTTYITQRPVYLGLPANLVDLKVPAKLLETPIDLSLKPNDPEAETEVVDTVLELIKAAKNPVILADACASRHDVKAETKKLIDATQFPSFVTPMGKGSIDEQHPRFGGVYVGTLSRPEVKEAVESADLILSVGALLSDFNTGSFSYSYKTKNIVEFHSDYIKIRNATFPGVQMKFALQKLLNAVPEAIKGYKPVPVPARVPENKSCDPATPLKQEWMWNQVSKFLQEGDVVITETGTSAFGINQTPFPNNAYGISQVLWGSIGFTTGACLGAAFAAEEIDPKKRVILFIGDGSLQLTVQEISTMIRWGLKPYLFVLNNDGYTIERLIHGEKAGYNDIQNWDHLALLPTFGAKDYENHRVATTGEWDKLTQDKEFNKNSKIRMIEVMLPVMDAPTSLIEQAKLTASINAKQE
InterPro domains: - IPR047213: Pyruvate decarboxylase/indolepyruvate decarboxylase-like, pyrimidine-binding domain (domain) [8-169]
- IPR000399: TPP-binding enzyme, conserved site (conserved_site) [427-446]
- IPR029061: Thiamin diphosphate-binding fold (homologous_superfamily) [4-553]
- IPR029035: DHS-like NAD/FAD-binding domain superfamily (homologous_superfamily) [183-345]
- IPR012001: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (domain) [5-110]
- IPR012000: Thiamine pyrophosphate enzyme, central domain (domain) [201-334]
- IPR047214: Pyruvate decarboxylase/indolepyruvate decarboxylase-like, PP-binding domain (domain) [364-549]
- IPR011766: Thiamine pyrophosphate enzyme, TPP-binding (domain) [405-517]
- IPR012110: Pyruvate decarboxylase/indolepyruvate decarboxylase-like (family) [1-562]
Interaction partners: - alcohol dehydrogenase
- Pyruvate kinase 1
- alcohol dehydrogenase
- Pyruvate kinase 2
- Candida glabrata strain CBS138 chromosome D complete sequence
- Aldehyde dehydrogenase
- S-
- alcohol dehydrogenase
- alcohol dehydrogenase
- Fructose-bisphosphate aldolase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016830 (carbon-carbon lyase activity), GO:0016831 (carboxy-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006520 (amino acid metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0006082 (organic acid metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0009081 (branched-chain amino acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0016053 (organic acid biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process), GO:0009082 (branched-chain amino acid biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062039 (biofilm matrix), GO:0062040 (fungal biofilm matrix)