Protein: Syndecan 2 (E5RJB8)
Organism: Homo sapiens (Human)
Subcellular location: Membrane; Single- pass type I membrane protein
Sequence: MYLDNSSIEEASGVYPIDDDDYASASGSGADEDVESPELTTSRPLPKILLTSAAPKVETTTLNIQNKIPAQTKSPEETDKEKVHLSDSERKMDPAEEDTNVYTEKHSDSLFKRTEVLAAVIAGGVIGFLFAIFLILL
InterPro domains: - IPR001050: Syndecan (family) [51-137]
- IPR027789: Syndecan/Neurexin domain (domain) [109-137]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0050793 (regulation of developmental process), GO:0023057 (negative regulation of signaling), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0051241 (negative regulation of multicellular organismal process), GO:0051239 (regulation of multicellular organismal process), GO:0051094 (positive regulation of developmental process), GO:0051093 (negative regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0048522 (positive regulation of cellular process), GO:0090287 (regulation of cellular response to growth factor stimulus), GO:0045597 (positive regulation of cell differentiation), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:2000026 (regulation of multicellular organismal development), GO:0010646 (regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0045595 (regulation of cell differentiation), GO:0090288 (negative regulation of cellular response to growth factor stimulus), GO:1901343 (negative regulation of vasculature development), GO:0009891 (positive regulation of biosynthetic process), GO:1902547 (regulation of cellular response to vascular endothelial growth factor stimulus), GO:1900746 (regulation of vascular endothelial growth factor signaling pathway), GO:0016525 (negative regulation of angiogenesis), GO:0045765 (regulation of angiogenesis), GO:0030947 (regulation of vascular endothelial growth factor receptor signaling pathway), GO:2000181 (negative regulation of blood vessel morphogenesis), GO:0016525 (negative regulation of angiogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0031984 (organelle subcompartment), GO:0005615 (extracellular space), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0012505 (endomembrane system), GO:0005576 (extracellular region), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0031090 (organelle membrane), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0070062 (extracellular exosome), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043230 (extracellular organelle), GO:0098827 (endoplasmic reticulum subcompartment), GO:0065010 (extracellular membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005789 (endoplasmic reticulum membrane), GO:0031982 (vesicle), GO:1903561 (extracellular vesicle)