wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Poly(A) RNA polymerase cid11 (PAP) (EC 2.7.7.19) (Caffeine-induced death protein 11) (Polynucleotide adenylyltransferase cid11) (O74326)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Sequence: MELLTFTCCPFEGQMQQKKRRFDANLVQLQESEHRNDQINETVDAELTNECWKLYMRLKPSNEEVSRRQQFVDKLRTILSTEIKDAKLDLFVFGSTENNLAIQQSDVDVCIITNGSKYLNSTCQLAQLLYSYGMKQIVCVSRARVPIVKIWDPQFDIHCDLNINNDVAKINTKMLRLFVSIDPRVRPLGLIIKYWAKQRALCDAAGSGTITSYTISCMLVNFLQTRNPPILPAMLDLMSNDDNKMFVDDIVGFKEKATLNKTSLGRLLIDFFYYYGFSFNYLDSVVSVRSGTVLNKQEKGWAMEVNNSLCVEEPFNTARNLANTADNPSVKGLQSEFQRAFRLMSENNACERLCKICEEYQFLDITNEANYGNTNTPFNTAYESFGCNHTVLPEAAAYPKPYYPPQITLSDGGNMNFLYYIPDESNHQSYENKANRDSDFQGQTSLTQGSAPPWHYIPCQSWLVWYPSEDASNPASGN
InterPro domains: - IPR002058: PAP/25A-associated (domain) [263-317]
- IPR043519: Nucleotidyltransferase superfamily (homologous_superfamily) [46-181]
- IPR054708: Poly(A) RNA polymerase, mitochondrial-like, central palm domain (domain) [47-179]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0003723 (RNA binding), GO:0016779 (nucleotidyltransferase activity), GO:0003729 (mRNA binding), GO:0070566 (adenylyltransferase activity), GO:0004652 (polynucleotide adenylyltransferase activity), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0006397 (mRNA processing), GO:0016071 (mRNA metabolic process), GO:0031123 (RNA 3'-end processing), GO:0043631 (RNA polyadenylation), GO:0006378 (mRNA polyadenylation), GO:0031124 (mRNA 3'-end processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Double-stranded RNA-binding protein 3 (dsRNA-binding protein 3) (AtDRB3) (Q9LJF5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Binds double-stranded RNA.
Sequence: MYKNQLQELAQRSCFSLPSYTCTREGPDHAPRFKASVNFNGEIFESPTYCSTLRQAEHSAAEVALSALSSKGPSKSLTARVLDETGIYKNLLQETAHRAGLDLPVYTSVRSGPGHIPTFSCTVELAGMSFNGESAKTKKQAEKNAAIAAWFSLRKMPRLDPLRGEEKEQEIVARVLSRFRPKEVKRREPNQSRRRTVIRTIRQNTTTTTTTTGDLLCEKLRSINLYTNEASSSSPPPQRFWPSRTNLTQEQSKVKSLLEKCQEYAEKKQSLDDPKPEMRIKTSSPSPLSSSVERNCYSKLLPFPSFVLNHQKLAPAVHIRSVIPVCSAPPPKPNPNPNSSPFITRELGNGSQEKKSLPN
InterPro domains: - IPR044451: AtDRB-like, second double-stranded RNA binding domain, plant (domain) [86-154]
- IPR044450: AtDRB-like, first double-stranded RNA binding domain, plant (domain) [1-69]
- IPR014720: Double-stranded RNA-binding domain (domain) [1-155]
Interaction partners: - Endoribonuclease Dicer homolog 3
- Protein argonaute 4
- Dicer-like protein 4
- Protein DCL homolog, chloroplastic
- Endoribonuclease Dicer homolog 2
- Endoribonuclease Dicer homolog 1
- Protein argonaute 7
- Protein argonaute 2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003725 (double-stranded RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0019222 (regulation of metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0009892 (negative regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0010629 (negative regulation of gene expression), GO:0010468 (regulation of gene expression), GO:0016070 (RNA metabolic process), GO:0031047 (RNA-mediated gene silencing), GO:0006396 (RNA processing), GO:0034470 (ncRNA processing), GO:0070918 (regulatory ncRNA processing), GO:0034660 (ncRNA metabolic process), GO:0035196 (miRNA processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Ladybird late, isoform C (A0A0B4KH37)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
Sequence: MPQRTPSPANSDVSVGSPSPPPLRSLNMKRLRLLRSPISLEHDRQKSSPVRVKSFSIADILGRGHEEDRVEKKPERIAIPNALPGVPAPLALINERLQIPLVPNCPPPAALHTFLSPALLHSYEQRLAWDYQRQLQEHFQAQAQLLRQMTLNPAIIASEDGSSERSQRSSSSNGSTECCSPTQAEKVEKRSQEDRMEVPKKSPEEQPKGASKSSGDTPLDALFQLSTKNFDEEQDPATLNIFATRSNPKKKRKSRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWFQNRRAKLKRDMEELKKDVQCEKIPDQSADPNRSHHNHPHYHQQHQHYAHMQSIGSDRDMDKDRCREKEKDKDKEELRMLKLMTLMRYSDGKLLYQQPPASYLPIPHRQNAD
InterPro domains: - IPR051892: LBX Family Transcription Factors (family) [45-399]
- IPR001356: Homeodomain (domain) [249-313]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [242-308]
- IPR017970: Homeobox, conserved site (conserved_site) [284-307]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0048856 (anatomical structure development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: MAGUK p55 scaffold protein 1 (A6NFY0)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MTLKASEGESGGSMHTALSDLYLEHLLQKRSRPEAVSHPLNTVTEDMYTNGSPAPGSPAQVKGQEGITLKLNEKQSCTVARILHGGMIHRQGSLHVGDEILEINGTNVTNHSVDQLQKAMKETKGMISLKV
InterPro domains: - IPR036034: PDZ superfamily (homologous_superfamily) [56-131]
- IPR001478: PDZ domain (domain) [62-131]
- IPR050716: Membrane-associated guanylate kinase (family) [64-131]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0035556 (intracellular signal transduction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0005793 (endoplasmic reticulum-Golgi intermediate compartment), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Uncharacterized protein YJR112W-A (Q3E743)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Not known
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Sequence: MVQLRRTITTNKVFQAITSTNDKVAHFVVFMWESWLFVKMFAEDIVTFRKLQANKYVLGVLICSLCASVTSEFAQSVVSRGQRVFDVKDIICNFWGSLLGVGIAFYQDR
InterPro domains: - IPR006976: VanZ-like (domain) [21-105]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0016791 (phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006629 (lipid metabolic process), GO:0019637 (organophosphate metabolic process), GO:0006793 (phosphorus metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0046486 (glycerolipid metabolic process), GO:0008610 (lipid biosynthetic process), GO:0006644 (phospholipid metabolic process), GO:0045017 (glycerolipid biosynthetic process), GO:0090407 (organophosphate biosynthetic process), GO:0006650 (glycerophospholipid metabolic process), GO:0046474 (glycerophospholipid biosynthetic process), GO:0008654 (phospholipid biosynthetic process), GO:0006656 (phosphatidylcholine biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0031090 (organelle membrane), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098827 (endoplasmic reticulum subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0005789 (endoplasmic reticulum membrane)