wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Glutamate--cysteine ligase (A0A1D8PE63)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Sequence: MGLLSIGTPLSWDESKKYNNHVRTNGITQLINIFKQHGHRENDVFLWGDEVEYMLVDFDKTNKTARLSIDKDYIINDLNDPEKLLPIAEKQDVSYHPEYGRFMVEATPAKPYNGNLLXXXXXXXXXXXXXXQLCEDNLPSHIKLLTLTTFPRMGCNIFTSPPSKSNGIASQSLFLPDDIINRHARFPTLTANIRKRKGHKVAINLPIYPDKSTKLLDDTIPQNRELFDSDKEPWIGASKPGFIYMDSMGFGMGSSCLQITMQTKNISQARYLYDSLAPIAPIMLSLSAAAPIFKGFLVDQDVRWNVVSGAVDDRTFIEKGQEPYSGYHLFGGLDIDAQDKLRINNHQINQQGDLLDLYTKDGKPIQRVPKSRYDSIDNYLNDNYYDTKYFQDEYNDLNAPINEQVYQRLIDEGKLDKYMANHFAHLFIRDPLVIFSERINQDNNLENDHFENIQSTNWQTLRFKPPALYTKDTDLTTKPGWRVEFRPMEIQLTDFENAAYSSFITLLSKAILKFQPNFYIPLSKVEINMKLAHKVDSTLKDKFWFRSFELWNIDPQEFDDYGFEWFDRFINGNQQQNGHVNNNNNNDKKTKNDPIIVNGSTTTTNGTNSGSGITETNGTMLPKGCEGKTVEEINDVDDNGIDQRYTICQLINGSGKFPGFIKLVIKLIATDLVPQALNNSTTSKEQLIEELIRLRSYLYLLATRANGEIPTTAHWVRNKVLQHQDYKQDSKVSEKITFDLIDDSIKITELKDRQLIEGFLGADITEYLMGSK
InterPro domains: - IPR004308: Glutamate-cysteine ligase catalytic subunit (family) [1-751]
- IPR014746: Glutamine synthetase/guanido kinase, catalytic domain (homologous_superfamily) [39-569]
Interaction partners: - Glutathione synthetase
- Glutathione hydrolase
- Ecm38p
- Cys-Gly metallodipeptidase DUG1
- 5-oxoprolinase
- Branched-chain-amino-acid aminotransferase
- Branched-chain-amino-acid aminotransferase
- Glutathione reductase
- Cysteine synthase
- cystathionine gamma-lyase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016874 (ligase activity), GO:0016879 (ligase activity, forming carbon-nitrogen bonds), GO:0016881 (acid-amino acid ligase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006749 (glutathione metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0006750 (glutathione biosynthetic process), GO:0006518 (peptide metabolic process), GO:0043043 (peptide biosynthetic process), GO:0019184 (nonribosomal peptide biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062039 (biofilm matrix), GO:0062040 (fungal biofilm matrix)
Protein: Dap1p (Q5A6R5)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Endoplasmic reticulum
Sequence: MLTTILIILIILYFARNIYNEFINNPSSPLDVSTEKESTIVEGKFTPISLTKYNGKDSPKIFIAVKNRVFDVTQGGAFYGPGGPYENFAGRDASRGLAKNSFDPDVLTDINEPIDTLTDLTAVEKESLDGWEEHFENRYKVVGTLHENGTVEEKS
InterPro domains: - IPR050577: MAPR/Neuferricin/Neudesin-like (family) [19-148]
- IPR036400: Cytochrome b5-like heme/steroid binding domain superfamily (homologous_superfamily) [38-147]
- IPR001199: Cytochrome b5-like heme/steroid binding domain (domain) [45-146]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0008047 (enzyme activator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0062012 (regulation of small molecule metabolic process), GO:1902930 (regulation of alcohol biosynthetic process), GO:0019216 (regulation of lipid metabolic process), GO:0046890 (regulation of lipid biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019218 (regulation of steroid metabolic process), GO:0050810 (regulation of steroid biosynthetic process), GO:0106118 (regulation of sterol biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: DASH complex subunit DAD4 (A0A1D8PTL5)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Nucleus
Sequence: MENPHEQTHNALLSRIINNMESLNESVVAVNKSLQQINNNNLQTEILSQMWENYIRNSEYNLEVTGLKKEPLFEKRE
InterPro domains: - IPR013959: DASH complex subunit Dad4 (family) [1-72]
Interaction partners: - DASH complex subunit DAD3
- DASH complex subunit SPC19
- DASH complex subunit DAD2
- DASH complex subunit SPC34
- Glycine cleavage system H protein
- Glycine cleavage system P protein
- DASH complex subunit DAD1
- DASH complex subunit DAM1
- Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial
- DASH complex subunit ASK1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0015631 (tubulin binding), GO:0008017 (microtubule binding), GO:0051010 (microtubule plus-end binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0030447 (filamentous growth)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098687 (chromosomal region), GO:0000940 (outer kinetochore), GO:0140513 (nuclear protein-containing complex), GO:0099080 (supramolecular complex), GO:0042729 (DASH complex), GO:0000776 (kinetochore), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000775 (chromosome, centromeric region), GO:0043228 (non-membrane-bounded organelle), GO:0000779 (condensed chromosome, centromeric region), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome), GO:0005634 (nucleus), GO:0000793 (condensed chromosome)
Protein: Ifd6p (A0A1D8PD78)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Sequence: MSIDKSKMVTRLGKSGLKVNTVAIGTMRLGSNWMGYNGDIDECLKILKFCYDNGFRTFDTADVYSNGKSEELLGLFIKKYNIPRERIVILTKCYFPVNDSDDKNWEDFDPVDSLNGKGLSRKHILAAVEDSVKRLGTYIDVLQIHRLDHEVTYEEIMHSLNDVVEKGLTRYIGASSMKAWEFVELQNVAKANGWHQFISMQSHYSLLYREDDRELNDYCKKNGVGLIPWSPNSGGVLCRPFDSEKTQKFFENKDWASVFGLGEPREADKTIVNRVEELSVKYNATMMQISLAWCIAKGVIPIAGVSKFEQAEELVGIYNVNLTEEDIKYLDEPYHAKDLAKEVN
InterPro domains: - IPR050523: Aldo/Keto Reductase Detoxification and Biosynthesis (family) [7-336]
- IPR036812: NAD(P)-dependent oxidoreductase domain superfamily (homologous_superfamily) [8-337]
- IPR023210: NADP-dependent oxidoreductase domain (domain) [22-332]
Interaction partners: - Glucoamylase 1
- Pyridoxine 4-dehydrogenase
- Oye32p
- Adh5p
- Glucoamylase 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051703 (biological process involved in intraspecies interaction between organisms), GO:0009987 (cellular process), GO:0044010 (single-species biofilm formation), GO:0098743 (cell aggregation), GO:0098630 (aggregation of unicellular organisms), GO:0090609 (single-species submerged biofilm formation), GO:0042710 (biofilm formation), GO:0044011 (single-species biofilm formation on inanimate substrate), GO:0090605 (submerged biofilm formation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005576 (extracellular region), GO:0031012 (extracellular matrix), GO:0062039 (biofilm matrix), GO:0062040 (fungal biofilm matrix)
Protein: nicotinamidase (A0A1D8PRE2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Sequence: MKKTALIVVDLQEDFLPPNGSLAIKNGRSVIPKINQLLPSQDNHSKFDWSLIVATQDWHPPNHTSFASQHENVAPFTEIEFIHPEKKLDPKTNQPIVMNQIVWPDHCVQGTKGAQLEPSFANQFEKLTKQDDNNTAPCKIVKKGYLPDREYYSCFQDCWGLHHTELIDLLHEYDIENVVFVGLAYDFCVLSSAIDSAKNGFKTFVLKNYCESVYPEKINDTDKLFIDNGVTIVDNDEKFDSLFK
InterPro domains: - IPR036380: Isochorismatase-like superfamily (homologous_superfamily) [2-235]
- IPR000868: Isochorismatase-like domain (domain) [4-217]
- IPR052347: Isochorismatase Family Nicotinamidases (family) [2-237]
Interaction partners: - Nicotinate phosphoribosyltransferase
- Trifunctional uridine nucleosidase/nicotinamide riboside hydrolase/nicotinic acid riboside hydrolase
- NAD-dependent protein deacetylase HST1
- NAD-dependent histone deacetylase SIR2
- NAD-dependent histone deacetylase HST3
- NAD-dependent protein deacylase
- NAD-dependent protein deacetylase HST2
- Purine nucleoside phosphorylase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0016811 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0048583 (regulation of response to stimulus), GO:0009605 (response to external stimulus), GO:0035821 (modulation of process of another organism), GO:0044403 (biological process involved in symbiotic interaction), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:0048585 (negative regulation of response to stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0080134 (regulation of response to stress), GO:0044003 (modulation by symbiont of host process), GO:0031348 (negative regulation of defense response), GO:0044414 (suppression of host defenses by symbiont), GO:0031347 (regulation of defense response), GO:0052200 (response to host defenses), GO:0052031 (modulation by symbiont of host defense response), GO:0030682 (mitigation of host defenses by symbiont)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062039 (biofilm matrix), GO:0062040 (fungal biofilm matrix)
Protein: NADP-dependent alcohol dehydrogenase (Q5AC33)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Sequence: MTTDSVPAKFQGFASSNKNTWNKPKLVSYDRKQINPHDVVLENEVCGLCYSDIHTLQSNWGEYNRDDLVVGHEIVGKVIAVGDKVTEFKIGQRVGIGAASSACRECNRCKSDNEQYCAKAASTYNAPDVRSNNYVTQGGYSSHSIADEQFVFPIPDDLPSAYAAPLMCAGITVFSPLLRNLGSDAKGKTVGIIGIGGLGHLALQLAKALGAKVVAFSRTSSKKDQALKLGADEFIATNEEKDWSSKYHDTFDFILNCASGVDGLNLQDYLSVLKVDKKFISVGLPPATEQFGVSPFTFLKHGASFGSSLLGSKVEVLEMLKLAAKHNVKPWIEEVPLSEENCSKALNRCHDGDVRYRFVFTEFDKAFAK
InterPro domains: - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [158-329]
- IPR002328: Alcohol dehydrogenase, zinc-type, conserved site (conserved_site) [71-85]
- IPR029752: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 (conserved_site) [190-217]
- IPR020843: Enoylreductase domain (domain) [19-310]
- IPR011032: GroES-like superfamily (homologous_superfamily) [22-180]
- IPR013149: Alcohol dehydrogenase-like, C-terminal (domain) [197-324]
- IPR047109: Cinnamyl alcohol dehydrogenase-like (family) [9-361]
- IPR013154: Alcohol dehydrogenase-like, N-terminal (domain) [36-156]
Interaction partners: - Aldehyde dehydrogenase domain-containing protein
- NADP-dependent oxidoreductase domain-containing protein
- Aldehyde dehydrogenase (NAD(P)(+))
- Pyruvate decarboxylase
- Pdc12p
- Aldehyde dehydrogenase
- Glycerol 2-dehydrogenase (NADP(+))
- Aldehyde dehydrogenase domain-containing protein
- Glycerol-1-phosphatase
- glycerol kinase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor), GO:0004033 (aldo-keto reductase (NADP) activity), GO:0008106 (alcohol dehydrogenase (NADP+) activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0019748 (secondary metabolic process), GO:0071704 (organic substance metabolic process), GO:0044550 (secondary metabolite biosynthetic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0009698 (phenylpropanoid metabolic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0009808 (lignin metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0009699 (phenylpropanoid biosynthetic process), GO:0009809 (lignin biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062039 (biofilm matrix), GO:0062040 (fungal biofilm matrix)
Protein: Fth1p (A0A1D8PEK3)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane; Multi- pass membrane protein
Sequence: MAGTSFEEYFSIQTFLIVFRETLESAIIISVLLSFVHQTFNGNTKKSNRDTRNQTYNSTESSSSLIPTESDDLTFEKNDAKLCRYLQLQIWIGGLLGLLVCLIIGAIILGIFYIIGNDLWTVAEHYWEGTFSIIASIIISVMGIKILRVNKMQEKWKLKLGKILQSSGYLNNSNNQQSFNKAGRTWATRIELWSEKYNMFILPFVTTLREGLEAIAVIGGIGINENTSVMALVNAAVLAIMSGILVGAILYRYGNTLSLKMFLITSTCFLYLVAAGLFSKGVWNFELQRFIDKCGGLDVSETGHGPGSYDIAISVWHVNCCNGEMQEDGVFWMVFTAILGWTNSATIGSVVSYNVYWIVIILVFWSLIYEEKNGFLPLIPISWQLKRIQKRKNLYQPLDAPEIGVHEEVRESMDSLNSETPLQR
InterPro domains: - IPR004923: Iron permease FTR1/Fip1/EfeU (family) [6-382]
Interaction partners: - Fet99p
- Ferroxidase
- Ferroxidase
- Fet31p
- High-affinity iron permease
- ferric-chelate reductase (NADPH)
- Siderophore transporter
- Fre9p
- Oxidoreductase
- Ftr2p
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0046873 (metal ion transmembrane transporter activity), GO:0046915 (transition metal ion transmembrane transporter activity), GO:0005381 (iron ion transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0042592 (homeostatic process), GO:0051234 (establishment of localization), GO:0048878 (chemical homeostasis), GO:0055085 (transmembrane transport), GO:0050801 (monoatomic ion homeostasis), GO:0098771 (inorganic ion homeostasis), GO:0034220 (monoatomic ion transmembrane transport), GO:0098660 (inorganic ion transmembrane transport), GO:0006810 (transport), GO:0098655 (monoatomic cation transmembrane transport), GO:0016192 (vesicle-mediated transport), GO:0098662 (inorganic cation transmembrane transport), GO:0055080 (monoatomic cation homeostasis), GO:0006811 (monoatomic ion transport), GO:0055072 (iron ion homeostasis), GO:0034755 (iron ion transmembrane transport), GO:0006812 (monoatomic cation transport), GO:0006897 (endocytosis), GO:0030001 (metal ion transport), GO:0000041 (transition metal ion transport), GO:0006826 (iron ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Peptidyl-prolyl cis-trans isomerase (Q59KZ2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Sequence: MASTSTGLPPNWTIRVSRSHNKEYFLNQSTNESSWDPPYGTDKEVLNAYIAKFKNNGYKPLVNEDGQVRVSHLLIKNNQSRKPKSWKSPDGISRTRDESIQILKKHLERILSGEVKLSELANTESDCSSHDRGGDLGFFSKGQMQPPFEEAAFNLHVGEVSNIIETNSGVHILQRTG
InterPro domains: - IPR036020: WW domain superfamily (homologous_superfamily) [5-39]
- IPR000297: Peptidyl-prolyl cis-trans isomerase, PpiC-type (domain) [65-177]
- IPR051370: Peptidyl-prolyl cis-trans isomerase Pin1 (family) [6-176]
- IPR001202: WW domain (domain) [6-40]
- IPR046357: Peptidyl-prolyl cis-trans isomerase domain superfamily (homologous_superfamily) [64-177]
Interaction partners: - 1-phosphatidylinositol-4-phosphate 5-kinase
- DNA-directed RNA polymerase subunit
- Large ribosomal subunit protein uL14m
- GSKIP domain-containing protein
- Multifunctional tryptophan biosynthesis protein
- rRNA adenine N(6)-methyltransferase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016853 (isomerase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0003755 (peptidyl-prolyl cis-trans isomerase activity), GO:0016859 (cis-trans isomerase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0030447 (filamentous growth), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0009607 (response to biotic stimulus), GO:0007154 (cell communication), GO:0009408 (response to heat), GO:0009266 (response to temperature stimulus), GO:0009991 (response to extracellular stimulus), GO:0031668 (cellular response to extracellular stimulus), GO:0044182 (filamentous growth of a population of unicellular organisms), GO:0036180 (filamentous growth of a population of unicellular organisms in response to biotic stimulus), GO:0042594 (response to starvation), GO:0071496 (cellular response to external stimulus), GO:0033554 (cellular response to stress), GO:0036170 (filamentous growth of a population of unicellular organisms in response to starvation), GO:0009267 (cellular response to starvation), GO:0031669 (cellular response to nutrient levels), GO:0031667 (response to nutrient levels), GO:0034605 (cellular response to heat)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Antisense-enhancing sequence 1 (A0A1D8PQ54)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Sequence: MPRIKQVDVFTNVKYLGNPVAVIYDSDNLTTQEMQKIARWTNLSETTFILTPKSSIADYSIRIFTSGGNELPFAGHPTLGTAFALLEDGKIKPNDNGQIIQECGAGLVKISVEKTPNNNSNNNNNNSNELPFLLSFQLPYFKFHEIDDKVIEELQHSWNGTNIIGKPVLIDAGPKWAVFQLGSGKEVLDLNVDLAQIERLSLENGWTGIGVFGKHNENGDSVELRNIAPAVGVAEDPACGSGSGAIGAYLANHVFNEKEKFTIDISQGKPIERGAKIQVKVNRLSTKNGDLSIHVGGHAITCFEGTYSI
InterPro domains: - IPR003719: Phenazine biosynthesis PhzF-like (family) [2-308]
Interaction partners: - Trp99p
- Ribosome maturation protein SDO1/SBDS N-terminal domain-containing protein
- pyridoxal 5'-phosphate synthase (glutamine hydrolyzing)
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016853 (isomerase activity), GO:0016854 (racemase and epimerase activity), GO:0016855 (racemase and epimerase activity, acting on amino acids and derivatives), GO:0036361 (racemase activity, acting on amino acids and derivatives), GO:0047661 (amino-acid racemase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhesion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062039 (biofilm matrix), GO:0062040 (fungal biofilm matrix)
Protein: Kinetochore-associated protein (Q5A9E6)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Chromosome, centromere, kinetochore. Nucleus. Note=Associated with the kinetochore
Sequence: MSADENNKVRFERLRLVARKALEQSIKKSLTMEQVKTCFPTLVTSQDGVRSLELALSQMSGFWHANSLDEFDLIYKEKDIESKLDELDDIIQNAQRTKDSGKEPSNIDQLSPLEIVDSTIVSNSKNVLDSLQMIYDQLCLDNAELYTELSELTKESTRINNSIKSGIEQLNKEANSVELEKAGLQIDKLIDILEEK
InterPro domains: - IPR016851: Kinetochore-associated protein Nnf1 (family) [5-190]
- IPR007128: Nuclear MIS12/MIND complex subunit PMF1/Nnf1 (family) [7-174]
Interaction partners: - Kinetochore protein mis13
- MIND complex subunit
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0022402 (cell cycle process), GO:0007049 (cell cycle), GO:0016043 (cellular component organization), GO:0007059 (chromosome segregation), GO:1903047 (mitotic cell cycle process), GO:0000278 (mitotic cell cycle), GO:0098813 (nuclear chromosome segregation), GO:0006996 (organelle organization), GO:0000070 (mitotic sister chromatid segregation), GO:0140014 (mitotic nuclear division), GO:0048285 (organelle fission), GO:0000819 (sister chromatid segregation), GO:0051276 (chromosome organization), GO:0000280 (nuclear division)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098687 (chromosomal region), GO:0099080 (supramolecular complex), GO:0000939 (inner kinetochore), GO:0000922 (spindle pole), GO:0043229 (intracellular organelle), GO:0000775 (chromosome, centromeric region), GO:0000776 (kinetochore), GO:0043228 (non-membrane-bounded organelle), GO:0000779 (condensed chromosome, centromeric region), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0005819 (spindle), GO:0005694 (chromosome), GO:0000793 (condensed chromosome), GO:0015630 (microtubule cytoskeleton)