wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Large ribosomal subunit protein eL18 (P35980)
Organism: Mus musculus (Mouse)
Function: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell
Subcellular location: Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity)
Sequence: MGVDIRHNKDRKVRRKEPKSQDIYLRLLVKLYRFLARRTNSTFNQVVLKRLFMSRTNRPPLSLSRMIRKMKLPGRENKTAVVVGTVTDDVRILEVPKLKVCALRVSSRARSRILKAGGKILTFDQLALESPKGRGTVLLSGPRKGREVYRHFGKAPGTPHSHTKPYVRSKGRKFERARGRRASRGYKN
InterPro domains: - IPR036227: Large ribosomal subunit protein uL15/eL18 superfamily (homologous_superfamily) [19-139]
- IPR000039: Large ribosomal subunit protein eL18 (family) [1-188]
- IPR021132: Large ribosomal subunit protein eL18, conserved site (conserved_site) [49-66]
- IPR021131: Large ribosomal subunit protein uL15/eL18 (domain) [2-188]
Interaction partners: - Large ribosomal subunit protein uL10
- Large ribosomal subunit protein uL3
- Small ribosomal subunit protein RACK1
- Large ribosomal subunit protein eL8
- Small ribosomal subunit protein uS13
- Small ribosomal subunit protein eS17
- Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein
- Large ribosomal subunit protein eL27
- Large ribosomal subunit protein uL15
- Large ribosomal subunit protein eL30
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0003735 (structural constituent of ribosome)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009790 (embryo development), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development), GO:0001701 (in utero embryonic development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0044391 (ribosomal subunit), GO:0043229 (intracellular organelle), GO:0022626 (cytosolic ribosome), GO:0043228 (non-membrane-bounded organelle), GO:0015934 (large ribosomal subunit), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0022625 (cytosolic large ribosomal subunit), GO:0005840 (ribosome)
Protein: Large ribosomal subunit protein eL28 (P41105)
Organism: Mus musculus (Mouse)
Function: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell
Subcellular location: Cytoplasm
Sequence: MSAHLQWMVVRNCSSFLIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVMKRRSGQRKPATSYVRTTINKNARATLSSIRHMIRKNKYRPDLRMAAIRRASAILRSQKPVVVKRKRTRPTKSS
InterPro domains: - IPR029004: Ribosomal eL28/Mak16 (domain) [5-120]
- IPR002672: Large ribosomal subunit protein eL28 (family) [1-132]
Interaction partners: - Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein uL24
- Large ribosomal subunit protein uL24
- Small ribosomal subunit protein uS7
- Small ribosomal subunit protein eS10
- Small ribosomal subunit protein eS10
- Large ribosomal subunit protein uL2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009790 (embryo development), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development), GO:0001701 (in utero embryonic development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0030054 (cell junction), GO:0044391 (ribosomal subunit), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0022626 (cytosolic ribosome), GO:0043228 (non-membrane-bounded organelle), GO:0015934 (large ribosomal subunit), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0022625 (cytosolic large ribosomal subunit), GO:0005840 (ribosome)
Protein: Large ribosomal subunit protein eL30 (P62889)
Organism: Mus musculus (Mouse)
Function: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell
Subcellular location: Cytoplasm
Sequence: MVAAKKTKKSLESINSRLQLVMKSGKYVLGYKQTLKMIRQGKAKLVILANNCPALRKSEIEYYAMLAKTGVHHYSGNNIELGTACGKYYRVCTLAIIDPGDSDIIRSMPEQTGEK
InterPro domains: - IPR022991: Large ribosomal subunit protein eL30, conserved site (conserved_site) [24-100]
- IPR004038: Ribosomal protein eL8/eL30/eS12/Gadd45 (domain) [13-105]
- IPR029064: Ribosomal protein eL30-like superfamily (homologous_superfamily) [2-108]
- IPR000231: Large ribosomal subunit protein eL30 (family) [12-109]
- IPR039109: Large ribosomal subunit protein eL30-like (family) [1-110]
Interaction partners: - Large ribosomal subunit protein eL19
- Large ribosomal subunit protein eL22
- Small ribosomal subunit protein eS25
- Small ribosomal subunit protein uS2
- Large ribosomal subunit protein uL14
- Large ribosomal subunit protein eL39
- Large ribosomal subunit protein eL39
- Large ribosomal subunit protein eL39
- Large ribosomal subunit protein uL6
- Small ribosomal subunit protein uS15
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:0009617 (response to bacterium), GO:0043207 (response to external biotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098794 (postsynapse), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0030054 (cell junction), GO:0044391 (ribosomal subunit), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0022626 (cytosolic ribosome), GO:0099572 (postsynaptic specialization), GO:0043228 (non-membrane-bounded organelle), GO:0098984 (neuron to neuron synapse), GO:0015934 (large ribosomal subunit), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0014069 (postsynaptic density), GO:0022625 (cytosolic large ribosomal subunit), GO:0032279 (asymmetric synapse), GO:0005840 (ribosome)
Protein: Large ribosomal subunit protein bL31B (P0A7N1)
Organism: Escherichia coli (strain K12)
Sequence: MKPNIHPEYRTVVFHDTSVDEYFKIGSTIKTDREIELDGVTYPYVTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRFVSTKKGA
InterPro domains: - IPR042105: Large ribosomal subunit protein bL31 superfamily (homologous_superfamily) [1-82]
- IPR002150: Large ribosomal subunit protein bL31 type A/B (family) [1-80]
- IPR034704: Large ribosomal subunit protein bL28/bL31-like superfamily (homologous_superfamily) [1-80]
- IPR027493: Large ribosomal subunit protein bL31 type B (family) [1-80]
Interaction partners: - Large ribosomal subunit protein bL36B
- Metal-binding protein ZinT
- Large ribosomal subunit protein bL28
- Small ribosomal subunit protein bS16
- Small ribosomal subunit protein bS16
- Small ribosomal subunit protein bS16
- Small ribosomal subunit protein bS16
- Large ribosomal subunit protein bL19
- Large ribosomal subunit protein bL21
- Small ribosomal subunit protein uS15
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0044877 (protein-containing complex binding), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0140098 (catalytic activity, acting on RNA), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0043021 (ribonucleoprotein complex binding), GO:0043022 (ribosome binding), GO:0004518 (nuclease activity), GO:0004540 (ribonuclease activity), GO:0004519 (endonuclease activity), GO:0004521 (RNA endonuclease activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0007154 (cell communication), GO:0009991 (response to extracellular stimulus), GO:0031668 (cellular response to extracellular stimulus), GO:0042594 (response to starvation), GO:0071496 (cellular response to external stimulus), GO:0033554 (cellular response to stress), GO:0031669 (cellular response to nutrient levels), GO:0009267 (cellular response to starvation), GO:0031667 (response to nutrient levels), GO:0120127 (response to zinc ion starvation), GO:0034224 (cellular response to zinc ion starvation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0044391 (ribosomal subunit), GO:0043229 (intracellular organelle), GO:0022626 (cytosolic ribosome), GO:0043228 (non-membrane-bounded organelle), GO:0015934 (large ribosomal subunit), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0022625 (cytosolic large ribosomal subunit), GO:0005840 (ribosome)
Protein: Large ribosomal subunit protein eL34 (Q9D1R9)
Organism: Mus musculus (Mouse)
Function: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell
Subcellular location: Cytoplasm, cytosol. Cytoplasm. Endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity)
Sequence: MVQRLTYRRRLSYNTASNKTRLSRTPGNRIVYLYTKKVGKAPKSACGVCPGRLRGVRAVRPKVLMRLSKTQKHVSRAYGGSMCAKCVRDRIKRAFLIEEQKIVVKVLKAQAQSQKAK
InterPro domains: - IPR038562: Large ribosomal subunit protein eL34, C-terminal domain superfamily (homologous_superfamily) [39-117]
- IPR018065: Large ribosomal subunit protein eL34, conserved site (conserved_site) [15-28]
- IPR008195: Large ribosomal subunit protein eL34 (family) [1-117]
Interaction partners: - Large ribosomal subunit protein eL8
- Large ribosomal subunit protein uL3
- Large ribosomal subunit protein uL10
- Small ribosomal subunit protein RACK1
- Large ribosomal subunit protein eL27
- Large ribosomal subunit protein uL15
- Large ribosomal subunit protein eL30
- Small ribosomal subunit protein eS8
- Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein
- Large ribosomal subunit protein uL29
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0019538 (protein metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006412 (translation), GO:0009059 (macromolecule biosynthetic process), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:0006518 (peptide metabolic process), GO:0010467 (gene expression), GO:0043043 (peptide biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm), GO:0030054 (cell junction), GO:0045202 (synapse)
Protein: Large ribosomal subunit protein bL36B (Q2EEQ2)
Organism: Escherichia coli (strain K12)
Sequence: MKVLNSLRTAKERHPDCQIVKRKGRLYVICKSNPRFKAVQGRKKKR
InterPro domains: - IPR000473: Large ribosomal subunit protein bL36 (family) [1-41]
- IPR035977: Large ribosomal subunit protein bL36 superfamily (homologous_superfamily) [1-41]
- IPR047621: Ribosomal protein L36, bacteria (family) [1-46]
Interaction partners: - Large ribosomal subunit protein bL31B
- Small ribosomal subunit protein uS14
- Small ribosomal subunit protein uS19
- Large ribosomal subunit protein bL32
- Large ribosomal subunit protein uL4
- Small ribosomal subunit protein uS17
- Large ribosomal subunit protein uL30
- Large ribosomal subunit protein uL3
- Large ribosomal subunit protein bL17
- Large ribosomal subunit protein uL29
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0005488 (binding), GO:0003735 (structural constituent of ribosome), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0019843 (rRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0043933 (protein-containing complex organization), GO:0006996 (organelle organization), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0065003 (protein-containing complex assembly), GO:0042254 (ribosome biogenesis), GO:0022618 (ribonucleoprotein complex assembly), GO:0042273 (ribosomal large subunit biogenesis), GO:0071826 (ribonucleoprotein complex subunit organization), GO:0042255 (ribosome assembly), GO:0140694 (non-membrane-bounded organelle assembly), GO:0000027 (ribosomal large subunit assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0022626 (cytosolic ribosome), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005840 (ribosome)
Protein: Large ribosomal subunit protein eL42 (P83882)
Organism: Mus musculus (Mouse)
Function: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell
Subcellular location: Cytoplasm
Sequence: MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF
InterPro domains: - IPR011332: Zinc-binding ribosomal protein (homologous_superfamily) [2-94]
- IPR053708: Eukaryotic Ribosomal Large Subunit eL42 (homologous_superfamily) [1-106]
- IPR000552: Large ribosomal subunit protein eL42 (family) [1-106]
Interaction partners: - Large ribosomal subunit protein eL24
- Large ribosomal subunit protein eL38
- Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein
- Large ribosomal subunit protein eL6
- Large ribosomal subunit protein eL33
- Large ribosomal subunit protein eL31
- Small ribosomal subunit protein uS14
- Small ribosomal subunit protein eS21
- Large ribosomal subunit protein eL30
- Small ribosomal subunit protein uS12
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0019538 (protein metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006412 (translation), GO:0009059 (macromolecule biosynthetic process), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:0006518 (peptide metabolic process), GO:0010467 (gene expression), GO:0043043 (peptide biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0030054 (cell junction), GO:0044391 (ribosomal subunit), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0022626 (cytosolic ribosome), GO:0043228 (non-membrane-bounded organelle), GO:0015934 (large ribosomal subunit), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0022625 (cytosolic large ribosomal subunit), GO:0005840 (ribosome)
Protein: Large ribosomal subunit protein bL36A (P0A7Q6)
Organism: Escherichia coli (strain K12)
Function: One of the last ribosomal proteins to be assembled in the 50S subunit, it contacts a number of helices in the 23S rRNA, acting as molecular glue. The simultaneous presence of uL16 and bL36 probably triggers ObgE's GTPase activity and eventual dissociation from the mature 50S ribosomal subunit
Sequence: MKVRASVKKLCRNCKIVKRDGVIRVICSAEPKHKQRQG
InterPro domains: - IPR000473: Large ribosomal subunit protein bL36 (family) [1-38]
- IPR035977: Large ribosomal subunit protein bL36 superfamily (homologous_superfamily) [1-38]
Interaction partners: - Large ribosomal subunit protein uL13
- Elongation factor G
- Elongation factor G
- Elongation factor G
- Small ribosomal subunit protein uS11
- Small ribosomal subunit protein uS7
- Alternative ribosome-rescue factor A
- Large ribosomal subunit protein uL15
- Large ribosomal subunit protein uL24
- Large ribosomal subunit protein uL14
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0005488 (binding), GO:0003735 (structural constituent of ribosome), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0019843 (rRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0043933 (protein-containing complex organization), GO:0006996 (organelle organization), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0065003 (protein-containing complex assembly), GO:0042254 (ribosome biogenesis), GO:0022618 (ribonucleoprotein complex assembly), GO:0042273 (ribosomal large subunit biogenesis), GO:0071826 (ribonucleoprotein complex subunit organization), GO:0042255 (ribosome assembly), GO:0140694 (non-membrane-bounded organelle assembly), GO:0000027 (ribosomal large subunit assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0044391 (ribosomal subunit), GO:0043229 (intracellular organelle), GO:0022626 (cytosolic ribosome), GO:0043228 (non-membrane-bounded organelle), GO:0015934 (large ribosomal subunit), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0022625 (cytosolic large ribosomal subunit), GO:0005840 (ribosome)