Protein: Exocyst complex component 5 (Exocyst complex component Sec10) (B0G163)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence: MSWARNIQSRIQQQQQLQKPGGLAPPSGNETPQKQPSSPTLSALSSPITSLTNALRGSGGISQPTTNTTSLTSTSPPSPTISTTTTQVKVGQTSFTTSTNLQAAASGNNLQASIQTTNITVTSPSMASPIGTSTGIQNPNAKPSSLPSPSQSPMQTRNTSAPTNNNNNNNTATTTTPTTTTTTTTTTTTTTTTTTTPSTSTTTTPTTSSSNLGQIQQQPPTLQQQQQQIQQQQQQQPTPIKQTTPYIFPNKIQPKSLTTDMFRGSEFSHVTFVEDLTRKLVNDQMGADGLHFEPAPFNQLFLNTQLQLSQLESNIDRRLDDLAEECNDFSYDYKRKLQDLTGSYQECFQHFKKLEKGVNTIGTKAVHFGDELDSVNQQKVKAQGALSLINYLLELNSVGASSEENGGITKRSDIFTNSDRIHELAHLVKKLSSVSEDIKEISGFKQGKLETESISNSLENDLLNQFERAAERNDYDKMKQCATTLHGFNGGERCRSRYIQKLKMFFDIDSFRKDENLANNITKRLIRGNNIVDTRFEIFYTDILKDVSHEQMVIQNVFVNQTSAMAMLIIRLFEQRVRLFIENVLSLESNNVSMFLQTVHYAFNSTKKLLVDPLQSYGIVGVDLNQLLNSIFYQYQEGYIQKETTYLVSLFQSNVVEECERLQTLDRYSMYLEDGLNPEITQMFVQQTENALTRSYTLSLDNILADNIKTIFFLMLEYLFEKYSMFVLNKYIELPMIPSSSSNVDTKSIQDSISQLFRVVLSINQIVGQIQSMFQVFVLPHIQTSMIVQSQCSDQLYFNISSLENTINTGLENSLTTMIQLIEKTLLPQGRNDYLIDDYDNSVTDTCASVIKLIQSFYDMAKINLQGKNFHIYVEELGLKSQFVFINHFKKFKIGQGIGTLKLMRDLTEYRNLSKQFKSQKVDDAFELLFEISKLHLVNPENFKLVIEGGALTRMSKQDLIIFIKQRSDFKSIWLDTL
InterPro domains: - IPR048625: Exocyst complex component Sec10, N-terminal (domain) [294-405]
- IPR048627: Exocyst complex component Sec10-like, alpha-helical bundle (domain) [424-974]
- IPR009976: Exocyst complex component Sec10-like (family) [254-976]
Interaction partners: - Exocyst complex component 7
- Exocyst complex component 3
- Exocyst complex component 4
- Exocyst complex component 8
- Exocyst complex component 6
- Exocyst complex component 2
- Exocyst complex component 1
- Protein transport protein sec1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0071840 (cellular component organization or biogenesis), GO:0051640 (organelle localization), GO:0006903 (vesicle targeting), GO:0140352 (export from cell), GO:0140029 (exocytic process), GO:0051649 (establishment of localization in cell), GO:0032940 (secretion by cell), GO:0016043 (cellular component organization), GO:0051648 (vesicle localization), GO:0090522 (vesicle tethering involved in exocytosis), GO:0051656 (establishment of organelle localization), GO:0006810 (transport), GO:0099022 (vesicle tethering), GO:0046903 (secretion), GO:0016192 (vesicle-mediated transport), GO:0006887 (exocytosis), GO:0051650 (establishment of vesicle localization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0099023 (vesicle tethering complex), GO:0031254 (cell trailing edge), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0000145 (exocyst), GO:0120025 (plasma membrane bounded cell projection), GO:0005938 (cell cortex), GO:0005886 (plasma membrane), GO:0098858 (actin-based cell projection), GO:0030175 (filopodium)