Protein: Sodium/hydrogen exchanger (B7YZY5)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MSIRTEQDYDSATPALAQQMNLARRACWRIKSYSSESLFKTYASVITDTSANEIDAEAPPPPRDKTKTRIEPQIAPAKRNSSCTSSDWRGMFSKRTLLICALALILGSAQARPNTSAVGVAPRKVSQDIVDAVTQLNLGQSAPIDAVDVGLDPTPSARVPRPEPLKSGDENAKGDEGHKMERYPLSSVDFARVKTPFIIGIWILSASIAKIGFHMTPKLHLIFPESCLLIVVGVVIGVVLYFCTDVAVSPLTPNTFFFYMLPPIILDAGYFMPNRLFFDNLGTILLMAVVGTIFNIATIGGSLYACGKMGIYGESETPGLMDVFLFASLISAVDPVAVLAVFEEIHVNEILYIVVFGESLLNDAVTVVMYHMMESYNEIGLDKIIAQDIASGVGSFFVVALGGTAIGIIWGFLTGLVTRFTDHVRVIEPIFIFVMAYLAYLNAEIFHMSGILAITFCGITMKNYVESNISQKSHTTVKYALKMLSSSAETIIFMFLGVATVNNMHVWNTWFVVLTIAFCSVFRVIGVILLSALANRFRLHKLSRVDQFVMSYGGLRGAVAFALVLLVDENVVKQKNMFVTTTIAVIYFTVFLQGITIKPLVKILNVKRANKRKPTMNERIHERFMDHLMAGIEDIVGKTGNYNVRDKFKRFDNRFIRPLLIRDLKVFLHLSL
InterPro domains: - IPR006153: Cation/H+ exchanger, transmembrane domain (domain) [203-602]
- IPR004709: Na+/H+ exchanger (family) [189-662]
- IPR018422: Cation/H+ exchanger, CPA1 family (family) [176-663]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0022853 (active monoatomic ion transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0015081 (sodium ion transmembrane transporter activity), GO:0015291 (secondary active transmembrane transporter activity), GO:0015297 (antiporter activity), GO:0015078 (proton transmembrane transporter activity), GO:0046873 (metal ion transmembrane transporter activity), GO:0140828 (metal cation:monoatomic cation antiporter activity), GO:0015385 (sodium:proton antiporter activity), GO:0051139 (metal cation:proton antiporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0032501 (multicellular organismal process), GO:0042592 (homeostatic process), GO:0048878 (chemical homeostasis), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0019725 (cellular homeostasis), GO:0009653 (anatomical structure morphogenesis), GO:0006885 (regulation of pH), GO:0050801 (monoatomic ion homeostasis), GO:0055082 (intracellular chemical homeostasis), GO:0009887 (animal organ morphogenesis), GO:0030641 (regulation of cellular pH), GO:0048513 (animal organ development), GO:0048731 (system development), GO:0090596 (sensory organ morphogenesis), GO:0055080 (monoatomic cation homeostasis), GO:0006873 (intracellular monoatomic ion homeostasis), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0048592 (eye morphogenesis), GO:0001654 (eye development), GO:0150063 (visual system development), GO:0030003 (intracellular monoatomic cation homeostasis), GO:0001745 (compound eye morphogenesis), GO:0048749 (compound eye development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)