wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Mimecan (Osteoglycin) (D3ZVB7)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
Sequence: MKTVHPTLLLLLFVPLTQQTPQTQLDSHVNSKYGTDNSEETKFIQDYEDKYLDGKNIKEKETMIIPDEKSLQLQKDEVIPSVPTKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADMPNLRRLDFTGNLIEDIEDGTFSKLSLLEELTLAENQLLRLPVLPPKLTLLNAKYNKIKSKGIKANTFKKLNKLSFLYLDHNDLESVPPNLPESLRVIHLQFNSISSITDDTFCKANDTRYIRERMEEIRLEGNPIALGKHPNSFICLKRLPTGSYF
InterPro domains: - IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [84-296]
- IPR003591: Leucine-rich repeat, typical subtype (repeat) [142-256]
- IPR001611: Leucine-rich repeat (repeat) [127-256]
- IPR043547: Mimecan/Epiphycan/Opticin (family) [1-298]
Interaction partners: - Osteomodulin
- Lumican
- Fibromodulin
- Prolargin
- Keratocan
- Adhesion G protein-coupled receptor L1
- Adhesion G protein-coupled receptor L3
- Adhesion G protein-coupled receptor L2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0003008 (system process), GO:0050877 (nervous system process), GO:0009888 (tissue development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0051216 (cartilage development), GO:0060348 (bone development), GO:0001501 (skeletal system development), GO:0007600 (sensory perception), GO:0061448 (connective tissue development), GO:0050954 (sensory perception of mechanical stimulus), GO:0007605 (sensory perception of sound)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005576 (extracellular region), GO:0005615 (extracellular space), GO:0031012 (extracellular matrix), GO:0062023 (collagen-containing extracellular matrix)
Protein: Dynein regulatory complex protein 8 (EF-hand calcium-binding domain-containing protein 2) (Q5VUJ9)
Organism: Homo sapiens (Human)
Function: Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
Subcellular location: Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:A8J3A0}.
Sequence: MLGPGQVRLRPRVWRDKAGGRVADGASGLPPARGSWRETGTGRALGASSPPRPAQGSSSPGIQSGPSSRPGSPRGAEQAGTPRPRLSLGISQATGSAARWRTRRTGKGLGYNSDEIRPRTLLIEHLMEGGRRDHHTMTVLWGTQEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEDGVSLRRPG
InterPro domains: - IPR011992: EF-hand domain pair (homologous_superfamily) [151-260]
- IPR002048: EF-hand domain (domain) [150-263]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0050794 (regulation of cellular process), GO:0010646 (regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0008277 (regulation of G protein-coupled receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Calcium sensor (NCS-1), putative (Q4WLA4)
Organism: Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata)
Function: Not known
Sequence: MGKSQSKLSPSQLEELQRATHFDKKELQQWYKGFLKDCPSGTLTKEEFQKIYRQFFPFGDPSSFANYVFRVFDSDNSGMIDFKEFICALSVTSRGKMEDKLDWAFQLYDIDGDGKITYDEMLAIVEAIYKMVGSMVKLPEDEDTPEKRVRKIFRMMDKDENGSLDMEEFKEGSKRDETIVSALSLYDGLV
InterPro domains: - IPR011992: EF-hand domain pair (homologous_superfamily) [1-188]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [73-169]
- IPR002048: EF-hand domain (domain) [60-179]
- IPR028846: Recoverin family (family) [5-181]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0005509 (calcium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0051703 (biological process involved in intraspecies interaction between organisms), GO:0099120 (socially cooperative development), GO:0048856 (anatomical structure development), GO:0030587 (sorocarp development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Islet amyloid polypeptide (Amylin) (D3Y4D2)
Organism: Sus scrofa (Pig)
Function: Not known
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Sequence: KCNMATCATQHLANFLDRSRNNLGTIFSPTKVGSNTY
InterPro domains: - IPR021116: Calcitonin/adrenomedullin (family) [1-37]
- IPR000443: Islet amyloid polypeptide (family) [11-37]
- IPR001693: Calcitonin peptide-like (domain) [1-37]
- IPR021117: Calcitonin-like (family) [1-37]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0001664 (G protein-coupled receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007186 (G protein-coupled receptor signaling pathway), GO:0007188 (adenylate cyclase-modulating G protein-coupled receptor signaling pathway), GO:0007189 (adenylate cyclase-activating G protein-coupled receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Stathmin-2 (Superior cervical ganglion-10 protein) (Protein SCG10) (P21818)
Organism: Rattus norvegicus (Rat)
Function: Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone.
Subcellular location: Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Cell projection, axon. Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Golgi apparatus. Endosome. Cell projection, lamellipodium {ECO:0000250}. Note=Colocalized with CIB1 in the cell body, neuritis and growth cones of neurons. Colocalized with CIB1 to the leading edge of lamellipodia (By similarity). Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. Exists in both soluble and membrane-bound forms. Colocalized with CIB1 in neurites of developing hippocampal primary neurons. {ECO:0000250}.
Sequence: MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYDDMEVKQINKRASGQAFELILKPPSPISEAPRTLASPKKKDLSLEEIQKKLEAAEGRRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVELSG
InterPro domains: - IPR030514: Stathmin, conserved site (conserved_site) [74-116]
- IPR000956: Stathmin family (family) [3-179]
- IPR036002: Stathmin superfamily (homologous_superfamily) [39-174]
Interaction partners: - Neuromodulin
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0150034 (distal axon), GO:0042995 (cell projection), GO:0044297 (cell body), GO:0005829 (cytosol), GO:0030427 (site of polarized growth), GO:0036477 (somatodendritic compartment), GO:0048471 (perinuclear region of cytoplasm), GO:0005737 (cytoplasm), GO:0043025 (neuronal cell body), GO:0120025 (plasma membrane bounded cell projection), GO:0097447 (dendritic tree), GO:0043229 (intracellular organelle), GO:0030426 (growth cone), GO:0043227 (membrane-bounded organelle), GO:0043005 (neuron projection), GO:0043231 (intracellular membrane-bounded organelle), GO:0030425 (dendrite), GO:0030424 (axon), GO:0005634 (nucleus)
Protein: Small ribosomal subunit protein uS9 (30S ribosomal protein S9) (P0A7X3)
Organism: Escherichia coli (strain K12)
Function: The C-terminal tail plays a role in the affinity of the 30S P site for different tRNAs. Mutations that decrease this affinity are suppressed in the 70S ribosome.
Sequence: MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETARMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAGFVTRDARQVERKKVGLRKARRRPQFSKR
InterPro domains: - IPR014721: Small ribosomal subunit protein uS5 domain 2-type fold, subgroup (homologous_superfamily) [1-130]
- IPR023035: Small ribosomal subunit protein uS9, bacterial/plastid (family) [1-130]
- IPR000754: Small ribosomal subunit protein uS9 (family) [3-130]
- IPR020568: Ribosomal protein uS5 domain 2-type superfamily (homologous_superfamily) [5-130]
- IPR020574: Small ribosomal subunit protein uS9, conserved site (conserved_site) [69-87]
Interaction partners: - Small ribosomal subunit protein uS7
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS17
- Small ribosomal subunit protein bS6
- Large ribosomal subunit protein uL15
- Alternative ribosome-rescue factor A
- Large ribosomal subunit protein uL14
- Large ribosomal subunit protein bL9
- Large ribosomal subunit protein bL33
- GTP pyrophosphokinase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0005488 (binding), GO:0003735 (structural constituent of ribosome), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0019843 (rRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0043933 (protein-containing complex organization), GO:0006996 (organelle organization), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0065003 (protein-containing complex assembly), GO:0042254 (ribosome biogenesis), GO:0042274 (ribosomal small subunit biogenesis), GO:0022618 (ribonucleoprotein complex assembly), GO:0071826 (ribonucleoprotein complex subunit organization), GO:0000028 (ribosomal small subunit assembly), GO:0042255 (ribosome assembly), GO:0140694 (non-membrane-bounded organelle assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0044391 (ribosomal subunit), GO:0043229 (intracellular organelle), GO:0022626 (cytosolic ribosome), GO:0043228 (non-membrane-bounded organelle), GO:0022627 (cytosolic small ribosomal subunit), GO:0015935 (small ribosomal subunit), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005840 (ribosome)
Protein: Probable G-protein coupled receptor 34 (Q6XCC7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Sequence: MSSTESLQSFSSVWDNRSMWSNRSCPLEEEALRLPLAVLYSLIFLFGLLGNLLALWVFLFLHRRRNSVRVFLINVALADLVLLACLPFRVLYHALGNVWTLGPRMCRVVGNLFYMNMYVSITLLGLISLDRYLKIMGSHRGRRWLRGRSWSLVTCGLLWGLSVLMAVPMMALAEGNEEPGKCYQYKQRKHARGKAYFNLVMVAVFWLVFVVLLVSYGQIARRLLRASQDKPHLPNAARYARTARKSFVVPLLFTVCFVPYHAFRGFYVASQLQDISCETRRLMDRTNEAVLLLSALNSCLDPVMYFLLSGSVRRATLQALAQCLRLHAEPPATNSSTTELRRTSVSHASTTAVLDTSRCSLGNITTLRSQHTDLHPHSEPCVHRSGLSD
InterPro domains: - IPR017452: GPCR, rhodopsin-like, 7TM (domain) [50-305]
- IPR048057: Probable G protein-coupled receptor 34, 7TM (domain) [34-316]
- IPR000276: G protein-coupled receptor, rhodopsin-like (family) [35-313]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004930 (G protein-coupled receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007186 (G protein-coupled receptor signaling pathway), GO:0007188 (adenylate cyclase-modulating G protein-coupled receptor signaling pathway), GO:0007193 (adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Rab11 interacting protein, isoform C (X2JEA7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004308}. Recycling endosome {ECO:0000256|ARBA:ARBA00004172}.
Sequence: MWSPTHCSVTVQRARGLLTKGKNGTNNCFVTIALGKEKYQTSVKDKAETSVNWNEECELKIPDQGNRAELTLTCLHRNNLGIDEFLGQATLPLNEMDVYDRPRAKWFKLESKPGKEKKNKERGELEVRIAFVVKSGSLTDLSKKDKHKSSIGQLASSVGGSLLSIGNGEKRRGIKKLAGSLSSKLHIRSKKKNQEAGADDSSSFGGSFASLGTPNSSNGRGQNGGSGRRRGGQRAGEADPGVISEDEDEFVFDNLSHKSSGSSLNIQRIGLQPPPVGTPNFTPRHPSPLLNNGVSGVGSGSAKDKYNNDNDSNSPSPKSTERIIIGHEKSGSHADRRSEISAQLAKKYEGKSREELMLIANGMENEALLQRQRVKELEDYLDNLLLRVMETHPKILQNPYSRTTSAKSYKNYINMNDFLK
InterPro domains: - IPR019018: Rab-binding domain FIP-RBD (domain) [337-399]
- IPR035892: C2 domain superfamily (homologous_superfamily) [5-156]
- IPR000008: C2 domain (domain) [1-109]
- IPR037245: FIP-RBD, C-terminal domain superfamily (homologous_superfamily) [370-401]
- IPR037789: Rab11-family interacting protein class I (family) [2-314]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0051020 (GTPase binding), GO:0031267 (small GTPase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0071840 (cellular component organization or biogenesis), GO:0009887 (animal organ morphogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0016043 (cellular component organization), GO:0022008 (neurogenesis), GO:0007399 (nervous system development), GO:0048880 (sensory system development), GO:0007423 (sensory organ development), GO:0090596 (sensory organ morphogenesis), GO:0006996 (organelle organization), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0042461 (photoreceptor cell development), GO:0048592 (eye morphogenesis), GO:0001654 (eye development), GO:0042052 (rhabdomere development), GO:0048699 (generation of neurons), GO:0046530 (photoreceptor cell differentiation), GO:0150063 (visual system development), GO:0001745 (compound eye morphogenesis), GO:0048749 (compound eye development), GO:0001754 (eye photoreceptor cell differentiation), GO:0042462 (eye photoreceptor cell development), GO:0042051 (compound eye photoreceptor development), GO:0001751 (compound eye photoreceptor cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0043226 (organelle), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle)
Protein: Palmitoyl-protein thioesterase 1 (EC 3.1.2.22) (Palmitoyl-protein hydrolase 1) (A0A2C9F2P4)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMDSCCNPLSMGAIKKMVEKKIPGIYVLSLEIGKTLMEDVENSFFLNVNSQVTTVCQALAKDPKLQQGYNAMGFSQGGQFLRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVDSEWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAHIIPFLG
InterPro domains: - IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [21-305]
- IPR002472: Palmitoyl protein thioesterase (family) [26-299]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0098599 (palmitoyl hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0008474 (palmitoyl-(protein) hydrolase activity), GO:0016790 (thiolester hydrolase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044237 (cellular metabolic process), GO:0061919 (process utilizing autophagic mechanism), GO:0009056 (catabolic process), GO:0016043 (cellular component organization), GO:0044248 (cellular catabolic process), GO:0006914 (autophagy), GO:0016236 (macroautophagy), GO:0000422 (autophagy of mitochondrion), GO:0006996 (organelle organization), GO:0022411 (cellular component disassembly), GO:0007005 (mitochondrion organization), GO:0000423 (mitophagy), GO:0061912 (selective autophagy), GO:1903008 (organelle disassembly), GO:0061726 (mitochondrion disassembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0005773 (vacuole), GO:0031090 (organelle membrane), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0005774 (vacuolar membrane), GO:0098588 (bounding membrane of organelle), GO:0005764 (lysosome), GO:0098852 (lytic vacuole membrane), GO:0005765 (lysosomal membrane)
Protein: Nimrod C1, isoform B (Nimrod C1, isoform C) (M9PBB4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MDFTAFSLHFVCLSLSFGTSFAILRHGLNDCSHPESVPYNRKVLKSKLVPFQQYSYFHGWVTKYRHQYVYEDETAYRTVMRPSCCEGYEGSVENCKPVCRQQCPQHGFCSSPNTCSCNAGYGGIDCHPVCPTVCGKNEFCDRPGVCSCQNGYKRTSPSDNCLPVCEKECGHHSFCSEPGKCECEPGYEKVGNGTVFPDGYKNNSNGNCSPICPKDCGQNSRCVRPGVCECENGYAGDDGGTNCRPVCSTCPENGLCLSPGVCVCKPGYVMRNDLCQPHCEKCSDNAHCVAPNQCECFPGYESSGADKKCVPKCSKGCTNGFCFAPETCVCSIGYQMGPNQVCEPKCSLNCVHGKCTSPETCTCDPGYRFKDNSHHECDPICDSGCSNGHCVAPNFCICHDGYQLNSTNPVTSMCQPICKGCQFGDCVAPNVCECNVGYENINGLCELQTTTDSYEYSTTTVELQSSTVDPQLQTSTSEVPHSNCTAGCMCWIEYDGMGTFNTAKCAKICVDPQDKPCLNLDNCQCDLSSGQLVCQEDSDMDYSGENSRYVCHILPEQGARSEAEVRIPDRTGSSNKWMIIVGSCAGMIIGVAATIIGIKYYRRSTSRRNFEAEEAIVECDFE
InterPro domains: - IPR053255: Epidermal growth factor-like domain-containing protein (family) [148-408]
- IPR011489: EMI domain (domain) [27-97]
- IPR000742: EGF-like domain (domain) [98-446]
Interaction partners: - Hemolectin, isoform A
- Atilla, isoform B
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0072341 (modified amino acid binding), GO:0008289 (lipid binding), GO:0005543 (phospholipid binding), GO:0001786 (phosphatidylserine binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0051234 (establishment of localization), GO:0009605 (response to external stimulus), GO:0006950 (response to stress), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006952 (defense response), GO:0043207 (response to external biotic stimulus), GO:0009617 (response to bacterium), GO:0006810 (transport), GO:0098542 (defense response to other organism), GO:0016192 (vesicle-mediated transport), GO:0042742 (defense response to bacterium), GO:0006909 (phagocytosis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Flagellar hook-basal body complex protein FliE (P24502)
Organism: Bacillus subtilis (strain 168)
Function: Not known
Subcellular location: Bacterial flagellum basal body {ECO:0000250}.
Sequence: MINAISPFQVQNTQNTQNATNQVNNSQKTDSSNQTSFSELLKNSISSLNESQVASDNMTNALAAGKDVNLDEVMIAAQKASISLTAATEFRNKAVEAYQEIMRMQM
InterPro domains: - IPR001624: Flagellar hook-basal body complex protein FliE (family) [3-106]
Interaction partners: - Flagellar motor switch phosphatase FliY
- Flagellar motor switch protein FliG
- Flagellar M-ring protein
- FlaA locus uncharacterized protein YlxG
- Probable flagellar assembly protein FliH
- Flagellar basal-body rod protein FlgG
- Flagellar basal-body rod protein FlgC
- Flagellar basal body rod protein FlgB
- Flagellum-specific ATP synthase
- Flagellar motor switch protein FliM
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0055085 (transmembrane transport), GO:0140352 (export from cell), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0032940 (secretion by cell), GO:0045184 (establishment of protein localization), GO:0071806 (protein transmembrane transport), GO:0006810 (transport), GO:0030254 (protein secretion by the type III secretion system), GO:0035592 (establishment of protein localization to extracellular region), GO:0071702 (organic substance transport), GO:0046903 (secretion), GO:0071705 (nitrogen compound transport), GO:0008104 (protein localization), GO:0009306 (protein secretion), GO:0015031 (protein transport), GO:0071692 (protein localization to extracellular region)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0042995 (cell projection), GO:0043226 (organelle), GO:0043228 (non-membrane-bounded organelle)