Protein: FZR1 protein (Fizzy and cell division cycle 20 related 1) (Fizzy-related protein homolog isoform 2) (Q5H7B9)
Organism: Sus scrofa (Pig)
Function: Not known
Sequence: MDQDYERRLLRQIIIQNENTMPCVAEMRRTLTPANSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPERKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKESVSVLNLFTRIR
InterPro domains: - IPR001680: WD40 repeat (repeat) [218-480]
- IPR056150: CDC20/Fizzy, WD40 domain (domain) [179-470]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [156-472]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [172-474]
- IPR019775: WD40 repeat, conserved site (conserved_site) [458-472]
- IPR033010: WD repeat Cdc20/Fizzy (family) [36-481]
Interaction partners: - Anaphase-promoting complex subunit 4
- Anaphase-promoting complex subunit 5
- Cell division cycle protein 27 homolog
- Cell division cycle protein 23 homolog
- Anaphase-promoting complex subunit 7
- Anaphase-promoting complex subunit 2
- Serine/threonine-protein kinase PLK
- Mitotic spindle assembly checkpoint protein MAD2A
- Cell division cycle 16
- Serine/threonine-protein kinase Nek2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:2000243 (positive regulation of reproductive process), GO:0044237 (cellular metabolic process), GO:2000241 (regulation of reproductive process), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0048522 (positive regulation of cellular process), GO:0051726 (regulation of cell cycle), GO:0090068 (positive regulation of cell cycle process), GO:1901564 (organonitrogen compound metabolic process), GO:0051445 (regulation of meiotic cell cycle), GO:0044248 (cellular catabolic process), GO:0019538 (protein metabolic process), GO:1903538 (regulation of meiotic cell cycle process involved in oocyte maturation), GO:0051446 (positive regulation of meiotic cell cycle), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0010564 (regulation of cell cycle process), GO:0043170 (macromolecule metabolic process), GO:0045787 (positive regulation of cell cycle), GO:0009057 (macromolecule catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0006508 (proteolysis), GO:0044265 (cellular macromolecule catabolic process), GO:0030163 (protein catabolic process), GO:0043632 (modification-dependent macromolecule catabolic process), GO:0010498 (proteasomal protein catabolic process), GO:0051603 (proteolysis involved in protein catabolic process), GO:0019941 (modification-dependent protein catabolic process), GO:0043161 (proteasome-mediated ubiquitin-dependent protein catabolic process), GO:0031145 (anaphase-promoting complex-dependent catabolic process), GO:0006511 (ubiquitin-dependent protein catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)