Protein: V-type proton ATPase subunit a (Q9CTA9)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: GVSAVAHRIPCQDMPPTLIRTNRFTSSFQGIVDAYGVGRYREVNPAPYTIITFPFLFAVMFGDVGHGLLMFLFALAMVLTENRPAVKAAQNEIWQTFFGGRYLLLLMGLFSVYTGFIYNECFSRATTIFPSGWSVAAMANQSGWSDEYLSQHSMLTLNPNITGVFLGPYPFGIDPIWSLATNHLSFLNSFKMKMSVILGVTHMAFGVFLSIFNHVHFGQAHRLLLETLPELIFLLGLFGYLVFLIVYKWVNVSAASASSAPSILIHFINMFLFSQNPTNHLLFHGQEVVQYVLVVLALATVPILLLGTPLYLVRQHRHRRNTQRRPAGQQDEDTDKLLASPDASTLENSWSPDEEKAGSPGDEETEFVPSEIFMHQAIHTIEFCLGCISNTASYLRLWALSLAHAQLSEVLWAMVMRIGLGMGREIGVAAVVLVPVFAAFAVLTVAILLVMEGLSAFLHALRLHWVEFQNKFYSGTGYKLSPFTFTVDSD
InterPro domains: - IPR002490: V-type ATPase, V0 complex, 116kDa subunit family (family) [2-486]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0008152 (metabolic process), GO:0042592 (homeostatic process), GO:0002376 (immune system process), GO:0051641 (cellular localization), GO:0048856 (anatomical structure development), GO:0009653 (anatomical structure morphogenesis), GO:0042221 (response to chemical), GO:0007163 (establishment or maintenance of cell polarity), GO:0045321 (leukocyte activation), GO:0008283 (cell population proliferation), GO:0006955 (immune response), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0048871 (multicellular organismal-level homeostasis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0065008 (regulation of biological quality), GO:0050793 (regulation of developmental process), GO:0019725 (cellular homeostasis), GO:0008219 (cell death), GO:0006885 (regulation of pH), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0061919 (process utilizing autophagic mechanism), GO:0001776 (leukocyte homeostasis), GO:0051640 (organelle localization), GO:0048869 (cellular developmental process), GO:0001775 (cell activation), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0032879 (regulation of localization), GO:0048771 (tissue remodeling), GO:0051234 (establishment of localization), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0033036 (macromolecule localization), GO:0048878 (chemical homeostasis), GO:0044237 (cellular metabolic process), GO:0001503 (ossification), GO:0002252 (immune effector process), GO:0006950 (response to stress), GO:0044238 (primary metabolic process), GO:0002260 (lymphocyte homeostasis), GO:0012501 (programmed cell death), GO:0002250 (adaptive immune response), GO:0044085 (cellular component biogenesis), GO:0030010 (establishment of cell polarity), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0044248 (cellular catabolic process), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0060255 (regulation of macromolecule metabolic process), GO:0051648 (vesicle localization), GO:0060041 (retina development in camera-type eye), GO:0046649 (lymphocyte activation), GO:0006914 (autophagy), GO:0055082 (intracellular chemical homeostasis), GO:0010035 (response to inorganic substance), GO:0009887 (animal organ morphogenesis), GO:0070661 (leukocyte proliferation), GO:0051656 (establishment of organelle localization), GO:0045595 (regulation of cell differentiation), GO:0016043 (cellular component organization), GO:0002443 (leukocyte mediated immunity), GO:1901575 (organic substance catabolic process), GO:0021675 (nerve development), GO:0050801 (monoatomic ion homeostasis), GO:0045851 (pH reduction), GO:1903530 (regulation of secretion by cell), GO:0051049 (regulation of transport), GO:1901564 (organonitrogen compound metabolic process), GO:0060341 (regulation of cellular localization), GO:0019538 (protein metabolic process), GO:0006952 (defense response), GO:0034762 (regulation of transmembrane transport), GO:0051649 (establishment of localization in cell), GO:0098771 (inorganic ion homeostasis), GO:0030641 (regulation of cellular pH), GO:0010817 (regulation of hormone levels), GO:0043170 (macromolecule metabolic process), GO:0010033 (response to organic substance), GO:0060249 (anatomical structure homeostasis), GO:0046883 (regulation of hormone secretion), GO:0048872 (homeostasis of number of cells), GO:0009888 (tissue development), GO:0010646 (regulation of cell communication), GO:0070887 (cellular response to chemical stimulus), GO:0046849 (bone remodeling), GO:0070727 (cellular macromolecule localization), GO:0001894 (tissue homeostasis), GO:0097186 (amelogenesis), GO:0030030 (cell projection organization), GO:0048880 (sensory system development), GO:0070201 (regulation of establishment of protein localization), GO:0030163 (protein catabolic process), GO:0042476 (odontogenesis), GO:0021545 (cranial nerve development), GO:0045453 (bone resorption), GO:0051650 (establishment of vesicle localization), GO:0010468 (regulation of gene expression), GO:0030098 (lymphocyte differentiation), GO:0022607 (cellular component assembly), GO:0002449 (lymphocyte mediated immunity), GO:0009057 (macromolecule catabolic process), GO:0051223 (regulation of protein transport), GO:0090276 (regulation of peptide hormone secretion), GO:0007399 (nervous system development), GO:0045667 (regulation of osteoblast differentiation), GO:0050708 (regulation of protein secretion), GO:0061484 (hematopoietic stem cell homeostasis), GO:0010467 (gene expression), GO:0042113 (B cell activation), GO:0010038 (response to metal ion), GO:0030097 (hemopoiesis), GO:0034097 (response to cytokine), GO:0002521 (leukocyte differentiation), GO:1901565 (organonitrogen compound catabolic process), GO:0071310 (cellular response to organic substance), GO:0051453 (regulation of intracellular pH), GO:0034765 (regulation of monoatomic ion transmembrane transport), GO:0007423 (sensory organ development), GO:0032880 (regulation of protein localization), GO:0006873 (intracellular monoatomic ion homeostasis), GO:0030099 (myeloid cell differentiation), GO:0055074 (calcium ion homeostasis), GO:0016236 (macroautophagy), GO:0006954 (inflammatory response), GO:0055080 (monoatomic cation homeostasis), GO:0090087 (regulation of peptide transport), GO:0006915 (apoptotic process), GO:0002460 (adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains), GO:0043029 (T cell homeostasis), GO:0031214 (biomineral tissue development), GO:0042110 (T cell activation), GO:0051046 (regulation of secretion), GO:0008104 (protein localization), GO:0070166 (enamel mineralization), GO:0043269 (regulation of monoatomic ion transport), GO:0006996 (organelle organization), GO:0010272 (response to silver ion), GO:0050796 (regulation of insulin secretion), GO:0071345 (cellular response to cytokine stimulus), GO:0150063 (visual system development), GO:0030003 (intracellular monoatomic cation homeostasis), GO:0034505 (tooth mineralization), GO:1903131 (mononuclear cell differentiation), GO:0007039 (protein catabolic process in the vacuole), GO:1904062 (regulation of monoatomic cation transmembrane transport), GO:0002573 (myeloid leukocyte differentiation), GO:0006874 (intracellular calcium ion homeostasis), GO:0051452 (intracellular pH reduction), GO:0090382 (phagosome maturation), GO:0070925 (organelle assembly), GO:0033365 (protein localization to organelle), GO:0001654 (eye development), GO:0030217 (T cell differentiation), GO:0021554 (optic nerve development), GO:1905037 (autophagosome organization), GO:0120036 (plasma membrane bounded cell projection organization), GO:0019724 (B cell mediated immunity), GO:0002791 (regulation of peptide secretion), GO:0007033 (vacuole organization), GO:0030183 (B cell differentiation), GO:0042475 (odontogenesis of dentin-containing tooth), GO:0046631 (alpha-beta T cell activation), GO:0030316 (osteoclast differentiation), GO:0016064 (immunoglobulin mediated immune response), GO:0031529 (ruffle organization), GO:0010155 (regulation of proton transport), GO:0035710 (CD4-positive, alpha-beta T cell activation), GO:0000045 (autophagosome assembly), GO:0043010 (camera-type eye development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0030141 (secretory granule), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0005773 (vacuole), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0000323 (lytic vacuole), GO:0030139 (endocytic vesicle), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0012506 (vesicle membrane), GO:0005770 (late endosome), GO:0030667 (secretory granule membrane), GO:0031982 (vesicle), GO:0030659 (cytoplasmic vesicle membrane), GO:0005764 (lysosome), GO:0030666 (endocytic vesicle membrane), GO:0097708 (intracellular vesicle), GO:0005634 (nucleus), GO:0045335 (phagocytic vesicle), GO:0030670 (phagocytic vesicle membrane)