Protein: MAX dimerization protein MGA a (A0A8M2B5I7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
Sequence: MADTEKQGAMVLHEEGVTAPTLAPPTTTPPSIFVVLKQLQSSDSGNDKANLMAISEANKMGKSSIGTTVAGIQPTSSTFADTNSTTPSENLPADARCRGITVTLDNNNMWNEFHRCKTEMILTKQGRRMFPYCRFRLSGMEPFQNYVLAMDIKPADNCRYKWSGKGWEPNGKAEPHISRLFVHPESPASGLHWMQYPVSFYRLKLCNTLDQEGHIILHSMHRYLPQIHIIPADKVSKDILILDRPNVVTLSFAQTEFFAVTAYQNLCITQLKIDYNPFAKGFREDAVNARSSKAKNGLSTDETESELKLSKEMTTLNNLKTLFMKRKASVKVNVNQNVPNPTNGENKVVNGAAPAVDTNVQSLCNKKRPSSLAFSDFIKGAHVKVKRLSLENINKTGGATEPSTACTSKQKEAADISSITENSLQVDQKDGNGAGDVLRCESTDTSLKTGVLKANEIKKEIDEHSADKNTLKSSDQNLSCSDEKKMETVSSLSTEAKPEAQMKKTLPHKRPERVPLPLLAKFLKQRRPILPKPVSHSSLSDSEKSCEPAQTSESSSVLMSFVPCVTTNLDSQPAVTSLSQTVTSSTTDANNMTSLSTTLSYSSTTVPLIPSETQLCDRFSASPVGSDPFSAPNTTSPSKPNSNPALDISNNTDAIFTPDHDNTLRSQSDISSDSTCDVVHDSCPPTVNTDTVETPVVPSPTSVFDVPSSTDNDMNSYQDINSMPDVAEGDSISDCLLDSSTGSCPEFFSEEIPQNTLFTNEESLSLPLDDASSPAFSLPSPAPSSPDPFPPSLFCDRPVPPRKALDSFPERLLDCTAASARDPFPLGFFNDGREPPRQIFDLPERPLIGTVASRESLSSSVNNGPEHPMETGDLFSQSHCPDRANSLNDLESAASCETAVSDNSISKPTKPSPHGSSCKKYKGKQKKVGMLKLGEDSEVFDGPVPVPLQPSLEDVEGQLFVSFMSKKALRIHLGDDDDDKPETAQENTDNPDGNNEEKIEKKIEGLEKVLLHDLKFMKNRQVIHPVLQEVGLKLNLLDVTLEIDLQYLGVQLPIPPPALSPEETSSQAQFVSRTGKTSDFTQIKGWRDKFAPSASLSEGVSSTDAGQSNLSAFCSDMLDEYLASEGKLIDERAASLSQADCTPVAYQLPTKSTSYVRTLDSVLKKQVPAILTPTTNKVKPTFKSKVENKSKKPLKPGKGKQTKPVISDAKPLCTKKPQQNKKYKSRKEFKSPEKPDVAEVPASNTTPMAEDSGSTSSTCAGGRSPGLPKTLVKLLDVEDGAVWEGRHRSYITEERAAIALATLVTAEGASTGSADAIRIIRRRAPPCLNVFCRLGCVCASLVHLRRHHHCGKPQCMLGCSCLRRKVVALKTPKQEEGTADDSDPQGMSEENKAKWRKKNKMRKTYVLTDPEIAPEPAKRVSTLWDRTRGNFDKEVLYCPPPPRSPQPQLLSQELQHDLESFLSPSKQKRVEERNLSTSEDNIEINLTCARSRPFHSNCHDKPKADDNKHHISQVSTPDIEEGELVPLNLSGPAKRLEMMSECTWTSIDMRNNVMRIVCEHMAQDRLNQPFWIGKYFIKPVSKTLEEEENGSVEIYKVIISQPMEKKTENEKVTQKEEELEKHVKTSEVKGLPFLSKCCPAGLLKAEKKSPDAPGQIMVNGKHYPQAKLELGHMGALHPANRLAAYITGRICPTVSAITKPPVTTVPSSTLTTVSKVTCTPASTTTSVSKSLAARSPLEKVFSQFVVNQINSQNVSNTSTSHLQPSVPKIVIPSPLLMIGKEAGAPSVALSSLKAGLVTKVSESSNSTGSTTIPTVSNVQVPAFTILTKSPSLPLGGSTLTTTTSASSPGLTSPAKKTVYITVASRNTGLSNSGTQIKKIVSPTGPPQTSGQKMLLQVVKTADGNTLYRNPNGQLMQLVPLSQIKALKPNLLSQGQPTIIRLPAPPTVSMNKPQGGSATIVTSSIPTTQTLAKPSGTVPVSTSSSMGGKLISPPSSKSVSLSSLPSTLKVVQGFLGQSGTCTLRILPPTTSTSSTVLSQSGLTLLKSASSMPPTQDSSNSETNVSFSSQSTEKTVVQVLKQSTIDPAKQNSSDNANVKEKHFNKAPDPEEKEIGSDSTELTDDSDLYSDDDQEDASCMSASDREEKIEDTDGMDSEKKGYAEMVVDIETIEESAEQNRIAKFRASALRRNQYRRNQKRIHDEMLEVRVQKVRKERKRRQTLSECFIKLQGTLGMSSKKFEVSRMRILTKANKEVEYLVKLEDYLVEKKAKLQFKKERYIQTLSQLCDKSTESIGLKLNEIISKQKALEAQSKTKETHPKPIQAKSKAKPKPKSKPKSKVVDVCDKPKGLAVQNKVNDVSKVTYSPSKPIDLSIKKQKSPEMTESVPKSTPSVSVPADLDGNKNTLNVLDTNTVTTTSTPIQPSFNSTLVMKPVSIPSPIKHPPITRERMRPNILSRASSQAMQGSPVKESLLTNVCIPQVLPLMNTMVPCNQIITINNSLQPIGITSVGQQSSTPGVASVSIVPTISHPLRVENTLPMLHPQFIKITNSPVNINTKVDSASLPNISNVISLAENLVVPRKVVEDKPVFQAQPTSVDNQQNSSNDKIPDLEQKTDEAPSTNVPKQSVVEDQKGASVPKSNPEVPENKSPDDSDDPEDENLLSLLDELVLLSQQLTNEDEDERIAVPGDVQSCSDKPEDQEPADDRALSPLFLTLDEDLMSPDSKDEIDIPPKVDDLVKVIFGSDSPSVSSESGVAQSTNASSPHASTCNATGDGLTPPPLLHMKAAYEAASGQSANEGTSVTWRPMPKLVPLGLKAQDAGKVINPSIPNLDSSEQDTPQM
InterPro domains: - IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [2205-2284]
- IPR036960: T-box superfamily (homologous_superfamily) [98-294]
- IPR008967: p53-like transcription factor, DNA-binding domain superfamily (homologous_superfamily) [99-285]
- IPR018186: Transcription factor, T-box, conserved site (conserved_site) [182-200]
- IPR046360: T-box transcription factor, DNA-binding domain (domain) [99-289]
- IPR001699: T-box transcription factor (family) [68-575]
- IPR032060: MGA, conserved domain (domain) [1322-1363]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048856 (anatomical structure development), GO:0023056 (positive regulation of signaling), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048584 (positive regulation of response to stimulus), GO:0007389 (pattern specification process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044237 (cellular metabolic process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0044238 (primary metabolic process), GO:0048522 (positive regulation of cellular process), GO:0090287 (regulation of cellular response to growth factor stimulus), GO:0009967 (positive regulation of signal transduction), GO:0048729 (tissue morphogenesis), GO:1901564 (organonitrogen compound metabolic process), GO:0048731 (system development), GO:0019538 (protein metabolic process), GO:0048513 (animal organ development), GO:0009966 (regulation of signal transduction), GO:0009799 (specification of symmetry), GO:0043170 (macromolecule metabolic process), GO:0006793 (phosphorus metabolic process), GO:0035295 (tube development), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0003002 (regionalization), GO:0009888 (tissue development), GO:0060322 (head development), GO:0010646 (regulation of cell communication), GO:0010647 (positive regulation of cell communication), GO:0007166 (cell surface receptor signaling pathway), GO:0009790 (embryo development), GO:0035239 (tube morphogenesis), GO:0060562 (epithelial tube morphogenesis), GO:0007167 (enzyme-linked receptor protein signaling pathway), GO:0055123 (digestive system development), GO:0048562 (embryonic organ morphogenesis), GO:0048732 (gland development), GO:0090092 (regulation of transmembrane receptor protein serine/threonine kinase signaling pathway), GO:0048854 (brain morphogenesis), GO:0003143 (embryonic heart tube morphogenesis), GO:0006796 (phosphate-containing compound metabolic process), GO:0030510 (regulation of BMP signaling pathway), GO:0002009 (morphogenesis of an epithelium), GO:0061008 (hepaticobiliary system development), GO:0036211 (protein modification process), GO:0007420 (brain development), GO:0009855 (determination of bilateral symmetry), GO:0043412 (macromolecule modification), GO:0048568 (embryonic organ development), GO:0007399 (nervous system development), GO:0003007 (heart morphogenesis), GO:0090100 (positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway), GO:0060972 (left/right pattern formation), GO:0035050 (embryonic heart tube development), GO:0072359 (circulatory system development), GO:0007417 (central nervous system development), GO:0031016 (pancreas development), GO:0009953 (dorsal/ventral pattern formation), GO:0060429 (epithelium development), GO:0048565 (digestive tract development), GO:0007507 (heart development), GO:0061371 (determination of heart left/right asymmetry), GO:0007368 (determination of left/right symmetry), GO:0048262 (determination of dorsal/ventral asymmetry), GO:0030513 (positive regulation of BMP signaling pathway), GO:0006468 (protein phosphorylation), GO:0001947 (heart looping), GO:0016310 (phosphorylation), GO:0048264 (determination of ventral identity), GO:0007178 (transmembrane receptor protein serine/threonine kinase signaling pathway), GO:0001889 (liver development), GO:0060389 (pathway-restricted SMAD protein phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex)