Protein: Signal transducer and activator of transcription (A0A8M2BFB6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm. Nucleus
Sequence: MSQWKQVQQLDIKFLEQVDYFYDDNFPMELRQVLANWIESQDWETASNHESMATVLFNNFLIQLERQCSQEQNFLHRHNLKRIFHQIQVKYKANPLQMAAVICNCLREERRILSTASMQEQGPLEKSMQNSAALEKQKVLDNKVAVIRSSVQMLDQAVKYLEDMQDDFDFRYKTLQLRDPLERNSSSMKQEVTTLQEILNRLDFKRKEFLSKTADVIKEIDALISSQLNPELKEWKRRQQIACIGGPVLIGLDQLQNWFTLTAQSLFQIKRQLDKLGELILKVTYESDPIPLQRPQMEEQVKYLIYHLIKSSFVVEKQPCMPTHLQKPLIIKTQVQFTTKVRLLVKLPEVDYQLKVKTTFDKDLPPGKVNRQFFILTNNTKVMDVEESTGCLSVEFRHLQLKERKCPTGGKGNEGPLSVTEELHSLNFEAMLMLQGLDIDLETCSLPLVVISNVSQLPGGWASVMWYNLLTDDPKNLAFFSNPLRASWSQLSEVLSWQFSSFAGRGLNKEQLNMLGDKLLGQHGSYNDCQVSWSKFCKEVIPGKSFSFWMWLDSILDLIKKHLLPVWIDGCIMGFVSKEMERALLKEKEPGTFLLRFSESHLGGITFTWVEQDENGDPKFISVEPYTKNRLNALPIADIIRDYKVIADGVVPENPLNFLYPDIPKDEAFGKHYNSQQNKVCPYIPTHLVPISHRVPAQHSCSSPEPPMSPGMYEIITQHLSPFEFESAMSSP
InterPro domains: - IPR012345: STAT transcription factor, DNA-binding, N-terminal (homologous_superfamily) [314-453]
- IPR036535: STAT transcription factor, N-terminal domain superfamily (homologous_superfamily) [1-123]
- IPR013800: STAT transcription factor, all-alpha domain (domain) [141-305]
- IPR048988: Signal transducer and activator of transcription, linker domain (domain) [474-552]
- IPR015988: STAT transcription factor, coiled coil (homologous_superfamily) [134-313]
- IPR036860: SH2 domain superfamily (homologous_superfamily) [563-692]
- IPR046991: Signal transducer and activator of transcription 4, coiled-coil domain (domain) [137-309]
- IPR008967: p53-like transcription factor, DNA-binding domain superfamily (homologous_superfamily) [314-562]
- IPR001217: Transcription factor STAT (family) [1-725]
- IPR013799: STAT transcription factor, protein interaction (domain) [2-119]
- IPR000980: SH2 domain (domain) [567-662]
- IPR013801: STAT transcription factor, DNA-binding (domain) [317-451]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0035295 (tube development), GO:0001568 (blood vessel development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0035239 (tube morphogenesis), GO:0048514 (blood vessel morphogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0001570 (vasculogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)