Protein: ZNF85 protein (Zinc finger protein 85) (Q49A12)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MSLSAQPSSSFYKPVSEVMCSHFAQDLWPEQNIKDSFQKVTLKRYGKCRHENLPLRKGCESMDECKMHKGGCNGLNQCLTATQSKIFQCDKYVKVAHKFSNSNRHEIRHTKKKPFKCTKCGKSFGMISCLTEHSRIHTRVNFYKCEECGKAFNWSSTLTKHKRIHTGEKPYKCEECGKAFNQSSNLIKHKKIHTGEKPYKCEECGKTFNRFSTLTTHKIIHTGEKPYKCKECGKAFNRSSTLTTHRKIHTGEKPYKCEECGKAFKQSSNLTTHKIIHTGEKPYKCKKCGKAFNQSAHLTTHEVIHTGEKPYKCEKCGKAFNHFSHLTTHKIIHTGEKPYKCKECGKAFKHSSTLTKHKIIHTGEKPYKCKECEKAFNQSSKLTEHKKIHTGEKPYECEKCGKAFNQSSNLTRHKKSHTEEKPYKCEECGKGFKWPSTLTIHKIIHTGEKPYKCEECGKAFNQSSKLTKHKKIHTGEKPYTCEECGKAFNQSSNLTKHKRIHTGEKPYKCEECDKAFKWSSVLTKHKIIHTGEKLQI
InterPro domains: - IPR013087: Zinc finger C2H2-type (domain) [115-534]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [79-525]
- IPR050752: C2H2-type zinc-finger domain-containing protein (family) [17-421]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0097159 (organic cyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0001217 (DNA-binding transcription repressor activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific), GO:0001227 (DNA-binding transcription repressor activity, RNA polymerase II-specific), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003677 (DNA binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding), GO:0000987 (cis-regulatory region sequence-specific DNA binding), GO:0000977 (RNA polymerase II transcription regulatory region sequence-specific DNA binding), GO:0000978 (RNA polymerase II cis-regulatory region sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0042592 (homeostatic process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0023057 (negative regulation of signaling), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0048771 (tissue remodeling), GO:0002682 (regulation of immune system process), GO:0051241 (negative regulation of multicellular organismal process), GO:0051239 (regulation of multicellular organismal process), GO:0048871 (multicellular organismal-level homeostasis), GO:0009892 (negative regulation of metabolic process), GO:0050793 (regulation of developmental process), GO:0002683 (negative regulation of immune system process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0065009 (regulation of molecular function), GO:0051093 (negative regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0060759 (regulation of response to cytokine stimulus), GO:0050790 (regulation of catalytic activity), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0035556 (intracellular signal transduction), GO:0080134 (regulation of response to stress), GO:0044092 (negative regulation of molecular function), GO:0080135 (regulation of cellular response to stress), GO:0009966 (regulation of signal transduction), GO:0060255 (regulation of macromolecule metabolic process), GO:0060761 (negative regulation of response to cytokine stimulus), GO:1903706 (regulation of hemopoiesis), GO:0051098 (regulation of binding), GO:0031324 (negative regulation of cellular metabolic process), GO:0010033 (response to organic substance), GO:0060249 (anatomical structure homeostasis), GO:1903707 (negative regulation of hemopoiesis), GO:2000026 (regulation of multicellular organismal development), GO:0010646 (regulation of cell communication), GO:0070887 (cellular response to chemical stimulus), GO:0045596 (negative regulation of cell differentiation), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0046849 (bone remodeling), GO:0051090 (regulation of DNA-binding transcription factor activity), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0045595 (regulation of cell differentiation), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0007166 (cell surface receptor signaling pathway), GO:0001894 (tissue homeostasis), GO:0080090 (regulation of primary metabolic process), GO:0034097 (response to cytokine), GO:0043086 (negative regulation of catalytic activity), GO:1902106 (negative regulation of leukocyte differentiation), GO:0001959 (regulation of cytokine-mediated signaling pathway), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0051100 (negative regulation of binding), GO:0051246 (regulation of protein metabolic process), GO:0071310 (cellular response to organic substance), GO:0060284 (regulation of cell development), GO:0051248 (negative regulation of protein metabolic process), GO:0070302 (regulation of stress-activated protein kinase signaling cascade), GO:0045453 (bone resorption), GO:1902532 (negative regulation of intracellular signal transduction), GO:0010468 (regulation of gene expression), GO:0043433 (negative regulation of DNA-binding transcription factor activity), GO:0045637 (regulation of myeloid cell differentiation), GO:0045638 (negative regulation of myeloid cell differentiation), GO:0031326 (regulation of cellular biosynthetic process), GO:0051101 (regulation of DNA binding), GO:0010563 (negative regulation of phosphorus metabolic process), GO:0007249 (I-kappaB kinase/NF-kappaB signaling), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:1902105 (regulation of leukocyte differentiation), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0051252 (regulation of RNA metabolic process), GO:0051338 (regulation of transferase activity), GO:0001960 (negative regulation of cytokine-mediated signaling pathway), GO:0010721 (negative regulation of cell development), GO:0051253 (negative regulation of RNA metabolic process), GO:0019221 (cytokine-mediated signaling pathway), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:1902531 (regulation of intracellular signal transduction), GO:0051174 (regulation of phosphorus metabolic process), GO:0002762 (negative regulation of myeloid leukocyte differentiation), GO:0043408 (regulation of MAPK cascade), GO:2000677 (regulation of transcription regulatory region DNA binding), GO:0043392 (negative regulation of DNA binding), GO:0031399 (regulation of protein modification process), GO:0031400 (negative regulation of protein modification process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0071345 (cellular response to cytokine stimulus), GO:0019220 (regulation of phosphate metabolic process), GO:0043549 (regulation of kinase activity), GO:0051348 (negative regulation of transferase activity), GO:0032088 (negative regulation of NF-kappaB transcription factor activity), GO:0010803 (regulation of tumor necrosis factor-mediated signaling pathway), GO:0070303 (negative regulation of stress-activated protein kinase signaling cascade), GO:0010804 (negative regulation of tumor necrosis factor-mediated signaling pathway), GO:1902679 (negative regulation of RNA biosynthetic process), GO:0032872 (regulation of stress-activated MAPK cascade), GO:0045936 (negative regulation of phosphate metabolic process), GO:0002761 (regulation of myeloid leukocyte differentiation), GO:0043409 (negative regulation of MAPK cascade), GO:0032873 (negative regulation of stress-activated MAPK cascade), GO:0006357 (regulation of transcription by RNA polymerase II), GO:0042325 (regulation of phosphorylation), GO:0001933 (negative regulation of protein phosphorylation), GO:0046328 (regulation of JNK cascade), GO:0001932 (regulation of protein phosphorylation), GO:0033673 (negative regulation of kinase activity), GO:0042326 (negative regulation of phosphorylation), GO:0043407 (negative regulation of MAP kinase activity), GO:0045671 (negative regulation of osteoclast differentiation), GO:2000678 (negative regulation of transcription regulatory region DNA binding), GO:0045892 (negative regulation of DNA-templated transcription), GO:0045859 (regulation of protein kinase activity), GO:1903507 (negative regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045670 (regulation of osteoclast differentiation), GO:0071900 (regulation of protein serine/threonine kinase activity), GO:0006469 (negative regulation of protein kinase activity), GO:0046329 (negative regulation of JNK cascade), GO:0000122 (negative regulation of transcription by RNA polymerase II), GO:0043508 (negative regulation of JUN kinase activity), GO:0071901 (negative regulation of protein serine/threonine kinase activity), GO:0043405 (regulation of MAP kinase activity), GO:0043506 (regulation of JUN kinase activity)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)