Protein: Protein ECM3 (Extracellular mutant protein 3) (Q99252)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: May be involved in cell wall organization and biogenesis.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Sequence: MTHITLGQAIWASVRPIIKIYLIIGVGFGLCKMNILTVQATRSISDIVLTILLPCLSFNKIVANIEDNDIKDVGIICLTSVILFATGLGFAFIVRSVLPVPKRWRGGILAGGMFPNISDLPIAYLQSMDQGFIFTEAEGEKGVANVIIFLAMFLICVFNLGGFRLIENDFHYKGDDDEENTLTNDDSAQQPTQPIEGNSSSSSNQDILKEPNESTVPNSSQASYISEKNKKEKTELSVPKPTHTAPPAIDDRSSNSSAVVSIDSITHSLRTNHVDAQSVSELNDPTYRTRSQPIAYTTESRTSHVHNNRRNSITGSLRSIDMRELPAEGMSDLIREYSNVDQYGRRRKSSISSQGAPSVLQADGTISPNLTRTSTLQRVKTSNLTRIITSDATVSKKDIETSGSSLPKWLQKFPLTKFFVFFLKNCLRPCSMAVILALIIAFIPWVKALFVTTSNTPKIKQAPDNAPALTFIMDFTSYVGAASVPFGLILLGATLGRLKIGKLYPGFWKSAVVLVFLRQCIMPIFGVLWCDRLVKAGWLNWENDKMLLFVTAITWNLPTMTTLIYFTASYTPEDETEPVQMECTSFFLMLQYPLMVVSLPFLVSYFIKVQMKL
InterPro domains: - IPR040254: Protein Ecm3-like (family) [1-613]
- IPR004776: Membrane transport PIN-like (family) [14-587]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0065007 (biological regulation), GO:0008514 (organic anion transmembrane transporter activity), GO:0005342 (organic acid transmembrane transporter activity), GO:0046943 (carboxylic acid transmembrane transporter activity), GO:0008028 (monocarboxylic acid transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0009628 (response to abiotic stimulus), GO:0042221 (response to chemical), GO:0055085 (transmembrane transport), GO:0050794 (regulation of cellular process), GO:0051234 (establishment of localization), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0104004 (cellular response to environmental stimulus), GO:0035556 (intracellular signal transduction), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0071214 (cellular response to abiotic stimulus), GO:0006810 (transport), GO:0006970 (response to osmotic stress), GO:0089718 (amino acid import across plasma membrane), GO:0098657 (import into cell), GO:0071705 (nitrogen compound transport), GO:0062197 (cellular response to chemical stress), GO:0071470 (cellular response to osmotic stress), GO:0071702 (organic substance transport), GO:0007231 (osmosensory signaling pathway), GO:0000160 (phosphorelay signal transduction system), GO:0015711 (organic anion transport), GO:0015695 (organic cation transport), GO:0003333 (amino acid transmembrane transport), GO:0006865 (amino acid transport), GO:0015849 (organic acid transport), GO:0046942 (carboxylic acid transport), GO:0015807 (L-amino acid transport), GO:0015804 (neutral amino acid transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)