Protein: E3 ubiquitin-protein ligase XBAT32 (EC 2.3.2.27) (Ankyrin repeat domain and RING finger-containing protein XBAT32) (Protein XB3 homolog 2) (RING-type E3 ubiquitin transferase XBAT32) (Q6NLQ8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: E3 ubiquitin-protein ligase that mediates ubiquitination of ACC synthases (ACS). Negatively regulates ethylene biosynthesis probably via ubiquitin-dependent degradation of ACS4 and ACS7 enzymes. Regulates lateral root formation and development by controlling ethylene production which inhibits lateral root formation at high concentration.
Sequence: MRFLSLVGNSFGCSASGERLVSAARDGDLQEAKALLDYNPRLARYSTFGVRNSPLHYSAAQGHHEIVSLLVESGVDINLRNYRGQTALMQACQHGHWEVVLILILFGANIHRSDYLNGGTALHLAALNGHPRCIRILLSEYIPSVPNCWSLLKNKKTSVAGFDSSVLHEVINRAADGGITPLHVAALNGHIETVQLLLDLGASVTQVTVEDGTTIDLIGAGSTALHYASCGGNTQCCQLLISKGACLAAVNSNGWTPMMVARSWHRNWLEEILNPTTEQPQLHLPNVPSPFLCLPLMSIVNIAQECGWRENDCLTPCRDPCAVCLERKCTVAADGCAHEFCTNCALYLSTTSITSSKTSNVTPGSVPCPLCRNGIVSFTKLPHTTATTRTSTSSRTSISLSFCTCSSDVLDTALLTNPHYSCKPVVSRTGSRTPQSARSSAFRSLSCRRFPPSLCLGGSDVDEPRSRLIGGSYSRSGVGFRRSTSQVEGKRSWFSALNHCVTTGGSAC
InterPro domains: - IPR017907: Zinc finger, RING-type, conserved site (conserved_site) [336-345]
- IPR036770: Ankyrin repeat-containing domain superfamily (homologous_superfamily) [13-303]
- IPR056760: E3 ubiquitin-protein ligase XB3-like, RING finger (domain) [321-377]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [309-393]
- IPR002110: Ankyrin repeat (repeat) [21-269]
- IPR001841: Zinc finger, RING-type (domain) [321-372]
Interaction partners: - Putative E3 ubiquitin-protein ligase XBAT35
- Ankyrin repeat domain-containing protein EMB506, chloroplastic
- 1-aminocyclopropane-1-carboxylate synthase 7
- Ankyrin repeat-containing protein BDA1
- Ethylene-overproduction protein 1
- ETO1-like protein 1
- E3 ubiquitin protein ligase RIE1
- ETO1-like protein 2
- 1-aminocyclopropane-1-carboxylate synthase 4
- BTB/POZ domain-containing protein At3g22104
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0070647 (protein modification by small protein conjugation or removal), GO:0032446 (protein modification by small protein conjugation), GO:0016567 (protein ubiquitination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)