wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Double-stranded RNA-binding protein Staufen homolog 1 (A0A8M1PJS2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site
Subcellular location: Cytoplasm. Rough endoplasmic reticulum
Sequence: MSQLQFQAPGNPAPSSAPLQLAPPQPGFSIPCGTAPLPSESASHPLRNSALPSASATPFCNPTVSNMANPKEKTPMCLVNELARYNKIQPEYKLLSEEGPAHSKIFSVRLTLGDQHWDAEGTSIKKAQHSAASSALAQTTLPKPSHRSPRHPGKSPGGIYKGSEYNVTHTVELNALCMKLGKKPIYKPIDAYQGMRPAFNYNIRAPSPYARSMQHYYYPFPPVGPVLYHMELSIGGQQFHGKGRTRQAAKHDAAAKAIKYLQKEPILQQITEMTDEPAQENLNKSEISQVFEIALKRNMPVDFEVLKEAGAPHMKSFVVRVVVGEFAGEGEGKSKKIAKKQAAIAVLEELRRLPQLPATDKIPLRIKKKSKSIIKLQTSPEYGQGMNPISRLAQIQQAKKEKEPEYTLVTERGLPRRREFVMQVSVAGQNAEGMGPSKKVAKRNAAEKMLELLGFKVPQPQPPKPALKTDEKPPAKKLGDGRKVTFFEPGSMEKAGLVVSKEEDFRLPFLSHQQLPAGILPMVPEVAQAVGANQGPHAKDYGRTAAPNPANATVTAMIANELLYAGTSPTAEGILKTNNSLAHRPQGPLTRPSEQLSYLANVQGLQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQSNERTANGPMSGCTKQDLEGDALLKPANSSTMGKTLDGTA
InterPro domains: - IPR014720: Double-stranded RNA-binding domain (domain) [74-455]
- IPR032478: Staufen, C-terminal (domain) [550-660]
- IPR044475: Staufen 1, third double-stranded RNA binding domain (domain) [284-350]
- IPR051740: Double-stranded RNA-binding domain-containing protein (family) [21-699]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0007276 (gamete generation), GO:0007281 (germ cell development), GO:0048468 (cell development), GO:0030154 (cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Exosome complex component RRP4 (F8W3K6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm. Nucleus, nucleolus
Sequence: MAVEMRLPAVHKHVSLKTGQSSREDKHLVVPGDVITSDTGFMRGHGTYMDEDRLTASVAGQVERVNKLICVKPLKTRYNGEVGDVVVGRITEVQQKRWKVETNSRLDSVLLLSAVNLPGGELRRRSTQDELAMRDYLQEGDLISAEVQSIFSDGALSLHTRSLKYGKLGQGVLVYVSPSLVKRQKTHFHNLPCGASLILGNNGYVWLSPTPALQEEQAGGFYTSMEPVSLSDREVVSRLRNCLLALANQKVLLFDTSVLYCYEASLQHQIKDILKPEIMEEIVLETRQRLMEHEG
InterPro domains: - IPR048565: RRP4, S1 domain (domain) [77-168]
- IPR025721: Exosome complex component, N-terminal domain (domain) [28-65]
- IPR012340: Nucleic acid-binding, OB-fold (homologous_superfamily) [76-169]
- IPR026699: Exosome complex RNA-binding protein 1/RRP40/RRP4 (family) [23-261]
- IPR004088: K Homology domain, type 1 (domain) [171-210]
- IPR036612: K Homology domain, type 1 superfamily (homologous_superfamily) [170-292]
Interaction partners: - Exosome complex component RRP45
- Exosome complex component MTR3
- Exosome complex component CSL4
- Exosome complex exonuclease RRP44
- Exosome complex component 10
- Nuclear nucleic acid-binding protein C1D
- Exosome complex component RRP40
- DIS3-like exonuclease 1
- SKI2 homolog, superkiller viralicidic activity 2-like
- M-phase phosphoprotein 6
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016787 (hydrolase activity), GO:0140098 (catalytic activity, acting on RNA), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0004518 (nuclease activity), GO:0004540 (ribonuclease activity), GO:0004532 (exoribonuclease activity), GO:0004527 (exonuclease activity), GO:0008408 (3'-5' exonuclease activity), GO:0016896 (RNA exonuclease activity, producing 5'-phosphomonoesters), GO:0016796 (exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters), GO:0000175 (3'-5'-RNA exonuclease activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0006950 (response to stress), GO:0019222 (regulation of metabolic process), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006952 (defense response), GO:0060255 (regulation of macromolecule metabolic process), GO:0043207 (response to external biotic stimulus), GO:0009615 (response to virus), GO:0098542 (defense response to other organism), GO:0140546 (defense response to symbiont), GO:0051607 (defense response to virus), GO:0010468 (regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Large ribosomal subunit protein eL22 (Q0VFW0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MAPKRQTVVRKNKKGACWKFTLDCTHPVEDGILDSANFETFLKEKVKVNGKTGNLGNVVQIVRQKNKINVTSEKQFSKRYLKYLTKKYLKKNNLRDWLRVVASDKESYELRYFQISQDDEESDADE
InterPro domains: - IPR038526: Large ribosomal subunit protein eL22 superfamily (homologous_superfamily) [7-126]
- IPR002671: Large ribosomal subunit protein eL22 (family) [6-122]
Interaction partners: - FAU ubiquitin-like and ribosomal protein S30 fusion b
- FAU ubiquitin-like and ribosomal protein S30 fusion a
- Large ribosomal subunit protein eL31
- Large ribosomal subunit protein uL5
- Ribosomal protein L4
- Large ribosomal subunit protein eL14
- Large ribosomal subunit protein eL30
- Ribosomal protein L26
- Large ribosomal subunit protein eL21
- Large ribosomal subunit protein eL27
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0030097 (hemopoiesis), GO:0060216 (definitive hemopoiesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Agouti-related protein (A0A8M1P467)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R. Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner
Subcellular location: Golgi apparatus lumen. Secreted
Sequence: MMLNTVIFGWFLVNVVVMASHPHLRRRENSFILTSDTDSLPEMEHLEINSAEEKILEDLEAYDEDLGKAVHLQRRGTRSPSRCIPHQQSCLGHHLPCCNPCDTCYCRFFKAFCYCRSMDNTCKNEYA
InterPro domains: - IPR007733: Agouti (family) [2-125]
- IPR036836: Agouti domain superfamily (homologous_superfamily) [70-125]
- IPR027300: Agouti domain (domain) [83-122]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (signaling receptor activator activity), GO:0048018 (receptor ligand activity), GO:0005179 (hormone activity), GO:0005184 (neuropeptide hormone activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0043473 (pigmentation), GO:0032501 (multicellular organismal process), GO:0048066 (developmental pigmentation), GO:0007154 (cell communication), GO:0007610 (behavior), GO:0007631 (feeding behavior), GO:0050795 (regulation of behavior), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0007632 (visual behavior)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0036477 (somatodendritic compartment), GO:0005615 (extracellular space), GO:0005576 (extracellular region), GO:0044297 (cell body), GO:0043025 (neuronal cell body)
Protein: DnaJ heat shock protein family (Hsp40) member B6b (A0A8M3B1D6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MEEDYYHILGVTKSASPDDIKKAYRKLALKWHPDKNPNDKEEAEKRFKEISEAYEVLSDENKRRDYDRYGKQGLSNRGGHYDDEYMGGFTFRNPEDVFREFFGGHDPFADFFADDTFEGFFGGRRHRGMSRSRTAGPFFPGFSPFGPSFSGFDTGFSPFGPMGGGSFSSFSSSPFGGGGGMRNFTSISTSTKFINGKRITTKRIVENGQERVEVEEDGQLKSLTVNAISDDSEERRRQNTLCGPAPHNRYLRNVAQNPSEKEEVEEEDRGLQNLGIAKGFFDTRRKKLSLKESDTKKKRTPRLTPRIGVWF
InterPro domains: - IPR036869: Chaperone J-domain superfamily (homologous_superfamily) [1-133]
- IPR001623: DnaJ domain (domain) [3-81]
- IPR043183: DnaJ homolog subfamily B member 2/6-like (family) [3-266]
- IPR018253: DnaJ domain, conserved site (conserved_site) [47-66]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0032182 (ubiquitin-like protein binding), GO:0043130 (ubiquitin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007610 (behavior), GO:0009888 (tissue development), GO:0061061 (muscle structure development), GO:0048513 (animal organ development), GO:0007626 (locomotory behavior), GO:0007517 (muscle organ development), GO:0060537 (muscle tissue development), GO:0007519 (skeletal muscle tissue development), GO:0060538 (skeletal muscle organ development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Angiopoietin-related protein 3 (A0A8N7UZN6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell projection, lamellipodium. Secreted
Sequence: MLMLILLLWLSLSTTSAAPNSKKSPTEAPILITAPPTEARSRFAMLDDVRLLANGLLQLGQSLREFVHKTKSQINDIFQKLNIFDRSFYQLSVVTSEIKEEEEKLKETTIFLKANNEEIRNLSLEINSKINNILQERSQLHTKVGGLEEKLKGLSQSMMPLEQLQEITALKDVIETQERTITDLLRSVKEQHDQLNYQKIKIKSLEDKVNYDTFQDTIEKPMDLNPETPDPFRYLTTNSTNGTKDINDFPADCSEVFTRGQKTSGIYPIKPNQSEPFYVYCEITPDGAATVIQRREDGSVDFDQSWEKYEHGFGKLEKEFWLGLAKIHSIAQQGEYILHIELEDWKEEKRFIEYTFTLEGPASDYALHLAPLSGDLSDAMSNHTGMKFSTKDRDNDNHDESNCARNYTGGWWFDACGDTNLNGRYAWMRSKARHQRRKGIYWRPSKGSSYTLKSTKITIRPSTQFQ
InterPro domains: - IPR036056: Fibrinogen-like, C-terminal (homologous_superfamily) [244-463]
- IPR037579: Fibrinogen/angiopoietin-like (family) [239-463]
- IPR014716: Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 (homologous_superfamily) [243-464]
- IPR002181: Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain (domain) [244-463]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140678 (molecular function inhibitor activity), GO:0004857 (enzyme inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0042592 (homeostatic process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0035265 (organ growth), GO:0008283 (cell population proliferation), GO:0007389 (pattern specification process), GO:0048871 (multicellular organismal-level homeostasis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0002262 (myeloid cell homeostasis), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0034101 (erythrocyte homeostasis), GO:0001568 (blood vessel development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0072089 (stem cell proliferation), GO:0048513 (animal organ development), GO:0009790 (embryo development), GO:0048872 (homeostasis of number of cells), GO:0035239 (tube morphogenesis), GO:0030097 (hemopoiesis), GO:0048568 (embryonic organ development), GO:0048514 (blood vessel morphogenesis), GO:0030218 (erythrocyte differentiation), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0030099 (myeloid cell differentiation), GO:0035162 (embryonic hemopoiesis), GO:0060319 (primitive erythrocyte differentiation), GO:0060215 (primitive hemopoiesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Cytospin-A (A0A8N7UV85)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration
Subcellular location: Cell junction, gap junction. Cytoplasm, cytoskeleton, spindle
Sequence: MLKGGTAKVALPRMGAPERAKLSTISSQSTYSGNIGMKTSRSSSTIASDLRLSKIKRASSDDALAKPVLGSVSRIKKTITTGAIAELTDNRPRSASSVQSTKKSGIPAPREIPQSISRERLSSRDQQKSSTAKKMVTSSSASSISALAKHSRGSVKTKAESAALDKTLLESQVRELLAEAKTKEFEISKLRTELQRHKGKDSPSEAGTPEGNSEMERTPALTGDVQVLVGELREKNGRFQRELATLREENQSLKQKLIALESASSSKHSVNGVVPDNINGSGLKTSVSSASDIKVSPLPSLDSSEFEKIPSRSDSVSSSIKSVVPSGVVKDLSVESLTERIQKMEESHHSTAEELQATLQELADQQQVVQELTAENERLAEEKGLLQTSLQQQRERVELLAQQNETLLQRLREQAQSQEAEASRASRMAELEQRLAEQVESSRFEREKLVDIQQQLTGSLRALEKENQEAQTAVKSLREEEGLLQGHLESEKLARDEAVRKTEEQRLAMEALRVDNASMKAQVEVERQKVAELKAVQSASDNTELQSLLKVAHEDRDKLEMTCTELRQELQQVEADRQQLLEKVEKQEQDHKANTNSLEEKSIDAENQIKDLKETIFELEDQVEQQRAVRLHTNQTILDLENQIKKLEDNKTELEKQIKVVNKQMKDETEEWRRFQADLQTAVVVANDIKVEAQQELRTLRRRLQEEQEHSARLASELEQIQGTRSWNEDASLSDSDGSPHWSRMTISQNAPVGFLTNGNGSGSSVSSEPEATVKSLIKSFDTATPNGSSSSVQIHTSPRSPLSGIPVRTAPAAAVSPIQRHSGIKPLSKTLERRIAFGDFPHNGSCDELKPSTLMRKSPSLESVIKTPAHFNGRTASFTYNRANSKLSVERTDPLSALAREYGGSKRNALLKWCQKKTEGYPNIDVTNFSSSWSDGLAFCALLHTYLPAHIPYQELISQDKGRNLTLAFQAAESIGIKPSLDFEELMRTDRPDWQSVMQYVSQIYKYFET
InterPro domains: - IPR001715: Calponin homology domain (domain) [905-1010]
- IPR036872: CH domain superfamily (homologous_superfamily) [898-1011]
- IPR050540: F-actin Monooxygenase Mical (family) [527-1010]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0003779 (actin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0009790 (embryo development), GO:0048729 (tissue morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0009888 (tissue development), GO:0016477 (cell migration), GO:0007369 (gastrulation), GO:0060027 (convergent extension involved in gastrulation), GO:0002009 (morphogenesis of an epithelium), GO:0060429 (epithelium development), GO:0001667 (ameboidal-type cell migration), GO:0060026 (convergent extension), GO:0042074 (cell migration involved in gastrulation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton)
Protein: Family with sequence similarity 49 member A (A0A8M2B7R9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Lipid- anchor
Sequence: MGNLLKVLTCTDFDQGPNFFLDFENAQPTDCEREVWNQVNAVLQESESILSGLQAYKGAGQEIRDAIQNPNDMLLQERAWNSVCPLVIRLKKFYAFSLKLEQALQSLLESLTCPPYTPTQHLEREQALAKQFAEILHFTLRFDELKMRIPAIQNDFSYYRRTISRNRLNNMNLDIENEVNNEMANRMSLFYAEATPMLKTLSTATTNFVTENKTLPLENTTDCLSTMASVCKVMLETPEYTSRFNSEDTLLFCMRVMVGVIILYDHVHPNGAFNKSSKIDMKGCIKVLKDQPADNVEGLLNALKFTTKHLNDESTPKNIRTMLQ
InterPro domains: - IPR039789: CYFIP-related Rac1 interactor (family) [1-324]
- IPR009828: CYRIA/CYRIB, Rac1 binding domain (domain) [18-320]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0002682 (regulation of immune system process), GO:0050793 (regulation of developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0051239 (regulation of multicellular organismal process), GO:0002520 (immune system development), GO:0050794 (regulation of cellular process), GO:0045595 (regulation of cell differentiation), GO:0002694 (regulation of leukocyte activation), GO:1903706 (regulation of hemopoiesis), GO:2000026 (regulation of multicellular organismal development), GO:0048534 (hematopoietic or lymphoid organ development), GO:0050865 (regulation of cell activation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048732 (gland development), GO:1902105 (regulation of leukocyte differentiation), GO:0051249 (regulation of lymphocyte activation), GO:0048538 (thymus development), GO:0060284 (regulation of cell development), GO:0045619 (regulation of lymphocyte differentiation), GO:0050863 (regulation of T cell activation), GO:0045580 (regulation of T cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0042995 (cell projection), GO:0043226 (organelle), GO:0120025 (plasma membrane bounded cell projection), GO:0043227 (membrane-bounded organelle), GO:0005929 (cilium)
Protein: Ubiquitin-conjugating enzyme E2N-like (Q7T3F3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MAGLPRRIIKETQRLLAEPVPGIKAEPDEGNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKSNEAQAIETARTWTRLYAGNNIEV
InterPro domains: - IPR016135: Ubiquitin-conjugating enzyme/RWD-like (homologous_superfamily) [1-152]
- IPR000608: Ubiquitin-conjugating (UBC), catalytic core domain (domain) [3-149]
- IPR023313: Ubiquitin-conjugating enzyme, active site (active_site) [76-91]
Interaction partners: - Ubiquitin-conjugating enzyme E2 variant 2
- A kinase (PRKA)-interacting protein 1
- TNF receptor-associated factor 6
- Ubiquitin-ribosomal protein eS31 fusion protein
- E3 ubiquitin-protein ligase rnf8
- Polyubiquitin-C
- Helicase-like transcription factor
- E3 ubiquitin-protein ligase CHIP
- E3 ubiquitin-protein ligase TRIP12
- Ubiquitin-ribosomal protein eL40 fusion protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0070647 (protein modification by small protein conjugation or removal), GO:0032446 (protein modification by small protein conjugation), GO:0016567 (protein ubiquitination), GO:0000209 (protein polyubiquitination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0140535 (intracellular protein-containing complex), GO:1990234 (transferase complex), GO:0031371 (ubiquitin conjugating enzyme complex)