Protein: Condensin complex subunit 1 (A0A8M1NUS6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases
Subcellular location: Chromosome. Cytoplasm. Nucleus
Sequence: MSWDFMVPVCLDDLVKSGAVNQYVVQDVLSAKQLPSHINSFKAAMRSQGPLSILEHFDTAYSVLKHCRTVDVAVKEDILELLIQVVRGLSVSLPTLLMAGTLSAVDRKQQLNAVKMSVFLLCKLTEMLESDSNRETIVTAPSKGRKKDKAAGKDLLQWDSERDTVLQCLTQLLQLDIRTLWSLSLVEEEFVSCVTCCCYKLLENPTISHMKNKSTRDAIIHVLGIMVKKYNHMLGACVKVIQLLQHFEQLASVCAQAVAAWSTEYGVKAIVGEIMREIGQKSSEELAREGSGVKAFSSFLSELGTLVPETMIPNISVLLTHLEGESPSLRVAVCEILGEVLVRVLSGDKLDDSARASRDRFLDTLQEHIHDAHSHVRARVLQVYTRIVNSKALPLSRYTEVMELTVGRLGDKSVNVCKSAIQLLAAFIAHNPYSCKLSSVDLKKPLEKEMAKLKEMRDAQAEQVPVAVITATDLWDAMKPEVELTVKALLEPGSEEEDDEEEEEEAAEGDRSDRDTAVQIAQFLRESKYKKAVGLCMRAHSLFPESSFFSDLADLNAESLINTLATLFKGPEEETPEAVSTDAPPTPQKESEGRESELKKQEMLVQYLKDTECFALQVERAIAVINNMLYWKTTTIVQEAVQFCVTAFEFSVADSVCGVRKMLPLVWSTDVTIKDAVIQAYRRLYLNPNGENTRAKAHTLVDSLSDLMVDASLGTIQCLEEIVQEFFSSESALQTSVMQVLWERFSGKRETKALHRRAAVLLLGMAGRAEREVVLSNLDTLCSVALGEKVAEDYLLARDTLITITNITDHVRQSKGVPFRLPMDHHLFSCLSQAIADGVVQSDPHWQTFMEQAVRLIYFLAESPDQLCSRLLQRSARLLLEQITEGGEPDQSQLQEGASQVSEEQVNCVSLAQVLSLCGAVAFWQVSHLERSVSSELRRRRGEKEEKEEKEKAPASKKGANDSCVEEELGLVGASAEDTEAEFIRKICETELLAEGNMLSAFLPLLVKVCSSPGKYSHPQLTTAACLALSQYMMISPAVCKDHIRLLFTVLEKSQLPVVRANTIVALGDLTVRFPNILEPWTPNLYARLSDENASVRLTAITVLTQLVLKDVMKVKGQVSEVAVLLLDPEPHIASLALNFFNELSAKDNAIYNLLPDIISRLSDPERGMNEEDFNTIMKQLFSYITKERQTESLVEKLCQRFRTAKTERQWADLAVSLSLLSVCERGFKKLQECWDCYSDKLAEPGVYQPLLSIAAKLRRRAKPQFKAQVEDYEKRLTAVHTKGLENVENEEREQQADTQSQNLHTPQAPKSVRRTTRGRGKPKVDDSDLVTPRKSRARPKPAITFTSDEEEEEDAVMAESETPKVTTPIARTRRTRLRH
InterPro domains: - IPR026971: Condensin subunit 1/Condensin-2 complex subunit D3 (family) [8-1356]
- IPR007673: Condensin subunit 1 (family) [5-1364]
- IPR016024: Armadillo-type fold (homologous_superfamily) [182-1221]
- IPR011989: Armadillo-like helical (homologous_superfamily) [157-1245]
- IPR032682: Condensin complex subunit 1, C-terminal (domain) [1058-1218]
- IPR024324: Condensin complex subunit 1, N-terminal (domain) [74-236]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0007389 (pattern specification process), GO:0071840 (cellular component organization or biogenesis), GO:0035295 (tube development), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0048729 (tissue morphogenesis), GO:0044085 (cellular component biogenesis), GO:0009888 (tissue development), GO:0003002 (regionalization), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009799 (specification of symmetry), GO:0009790 (embryo development), GO:0016043 (cellular component organization), GO:0035239 (tube morphogenesis), GO:0009855 (determination of bilateral symmetry), GO:0060562 (epithelial tube morphogenesis), GO:0048568 (embryonic organ development), GO:0030030 (cell projection organization), GO:0003007 (heart morphogenesis), GO:0060972 (left/right pattern formation), GO:0035050 (embryonic heart tube development), GO:0048562 (embryonic organ morphogenesis), GO:0072359 (circulatory system development), GO:0022607 (cellular component assembly), GO:0003143 (embryonic heart tube morphogenesis), GO:0002009 (morphogenesis of an epithelium), GO:0060429 (epithelium development), GO:0006996 (organelle organization), GO:0007507 (heart development), GO:0070925 (organelle assembly), GO:0061371 (determination of heart left/right asymmetry), GO:0007368 (determination of left/right symmetry), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0044782 (cilium organization), GO:0001947 (heart looping), GO:0120031 (plasma membrane bounded cell projection assembly), GO:0060271 (cilium assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)