Protein: U-box domain-containing protein 12 (EC 2.3.2.27) (Plant U-box protein 12) (OsPUB12) (RING-type E3 ubiquitin transferase PUB12) (Q5VRH9)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Possesses E3 ubiquitin-protein ligase in vitro.
Sequence: MPKRVADEIAALPEPRGPLRRPCADLSRRVRLLAPLLDHLPASSSSSSSTPLADALGAARDLLRKTRDGSKIDQAMRGDAFLDEFAGVNRQIHLALDALPYNTFHMPQEVQEQVALVHSQFQRASTRTDPPDTQLSMDLAWALTDNPSDPALLTRISHKLQLHTMADMKNESIALHNMVISTAGEPDGCVDQMSSLLKKLKDCVVTEDHANDALTTRSASIKHRSPIIPDEFRCPISLELMQDPVIVSSGQTYERSCIQKWLDSGHKTCPKTQQPLSHTSLTPNFVLKSLISQWCEANGIELPKNKQNSRDKKAAKSSDYDHAGLVSLMNRLRSGNQDEQRAAAGEIRLLAKRNVNNRICIAEAGAIPLLVNLLSSSDPRTQEHAVTALLNLSIHENNKASIVDSHAIPKIVEVLKTGSMETRENAAATLFSLSVVDENKVTIGAAGAIPPLINLLCDGSPRGKKDAATAIFNLCIYQGNKVRAVKAGIVIHLMNFLVDPTGGMIDEALSLLSILAGNPEGKIVIARSEPIPPLVEVIKTGSPRNRENAAAILWLLCSADTEQTLAAKAAGVEDALKELSETGTDRAKRKASSILELMHQANEDSLKGNGH
InterPro domains: - IPR016024: Armadillo-type fold (homologous_superfamily) [321-600]
- IPR003613: U-box domain (domain) [227-301]
- IPR045210: PUB protein, U-box domain, plant (domain) [229-281]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [228-301]
- IPR011989: Armadillo-like helical (homologous_superfamily) [321-597]
- IPR057623: PUB 12/19-like, N-terminal domain (domain) [20-124]
- IPR000225: Armadillo (repeat) [354-558]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0071704 (organic substance metabolic process), GO:2000241 (regulation of reproductive process), GO:0048523 (negative regulation of cellular process), GO:0006807 (nitrogen compound metabolic process), GO:0048585 (negative regulation of response to stimulus), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0060548 (negative regulation of cell death), GO:0010941 (regulation of cell death), GO:0043170 (macromolecule metabolic process), GO:2000028 (regulation of photoperiodism, flowering), GO:0080134 (regulation of response to stress), GO:0031348 (negative regulation of defense response), GO:0036211 (protein modification process), GO:0031347 (regulation of defense response), GO:0043412 (macromolecule modification), GO:0048586 (regulation of long-day photoperiodism, flowering), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:0070647 (protein modification by small protein conjugation or removal), GO:0032446 (protein modification by small protein conjugation), GO:0016567 (protein ubiquitination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)