Protein: Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (T-cell activation antigen CD26) (M1PFC6)
Organism: Pipistrellus pipistrellus (Common pipistrelle)
Function: Not known
Subcellular location: Apical cell membrane {ECO:0000256|ARBA:ARBA00004655}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004655}. Cell projection, invadopodium membrane {ECO:0000256|ARBA:ARBA00004341}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004341}. Cell projection, lamellipodium membrane {ECO:0000256|ARBA:ARBA00004485}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004485}. Membrane raft {ECO:0000256|ARBA:ARBA00004285}. Secreted {ECO:0000256|ARBA:ARBA00004613}.
Sequence: MKTPWKVLLGLLGTAALVTIITVPAVLLSQGNDADTRRTYTLSDYLKSTIRTRNYNLRWISDHEYLYRQENNILLFNADHGNSSTFLENSTFDQFGYSINDYSVSPDRRFVLLEYNYVKKWRHSYTASYDIYDLNKRQLITEERIPNDTQLISWSPEGHKLAYVWNNDIYIKNDPNSPPQRVTDDGREDAISNGITDWVYEEEIFSTHSALWWSPNGTFLAYARFNDTEVPRIEYSVYLDESLQYPKTVHLPYPKAGAENPTVKLYVVNTDNLTNLVPVQITAPASVLTGDHYLCDVTWATKERISLQWLRRTQNYSIIDICDYDAPNSKWNCSVPRQHIEMSTTGWVGRFKPAEPHFTADGNSFYKIMSNSEGYKHICYFQVDNQKCTFITNGTWEVIKIEALTNNYLYYISNEYKGMPGGRNLYKIQLNNITNVACLSCELDPERCQYYSASFSKGAKYYQLRCSGPQLPRYSLHSSSNDKELRLLENNTALYETLRNIKMPRKTLDVIHLHGMKFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADATFSLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRKLGTLEVEDQIEAARQFSKMGFVDDKRIAIWGWSYGGYVTSMVLGAGSGVFKCGIAVAPVSAWEFYDSVYTERYMGLPTPGDNLEHYKNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQITKALVDAGVDFQAMWYTDEDHGIASNTAHQHIYTHMTHFLKQCFSLP
InterPro domains: - IPR002471: Peptidase S9, serine active site (active_site) [599-629]
- IPR002469: Dipeptidylpeptidase IV, N-terminal domain (domain) [105-472]
- IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [498-760]
- IPR050278: Serine protease S9B/DPPIV (family) [10-757]
- IPR001375: Peptidase S9, prolyl oligopeptidase, catalytic domain (domain) [554-757]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008238 (exopeptidase activity), GO:0008239 (dipeptidyl-peptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0006508 (proteolysis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0009986 (cell surface), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0005773 (vacuole), GO:0031090 (organelle membrane), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0005774 (vacuolar membrane), GO:0098588 (bounding membrane of organelle), GO:0005764 (lysosome), GO:0098852 (lytic vacuole membrane), GO:0005765 (lysosomal membrane)