Protein: Bidirectional sugar transporter SWEET17 (AtSWEET17) (Protein SUGARS WILL EVENTUALLY BE EXPORTED TRANSPORTERS 17) (Q84WN3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as a vacuolar hexose transporter. Regulates fructose (Fru) homeostasis in leaves and roots by exporting/importing Fru through the tonoplast regarding metabolic demand.
Subcellular location: Vacuole membrane {ECO:0000269|PubMed:23583552, ECO:0000269|PubMed:24381066, ECO:0000303|PubMed:25988582}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8L9J7}.
Sequence: MAEASFYIGVIGNVISVLVFLSPVETFWKIVKRRSTEEYKSLPYICTLLGSSLWTYYGIVTPGEYLVSTVNGFGALVETIYVSLFLFYAPRHLKLKTVDVDAMLNVFFPIAAIVATRSAFEDEKMRSQSIGFISAGLNIIMYGSPLSAMKTVVTTKSVKYMPFWLSFFLFLNGAIWAVYALLQHDVFLLVPNGVGFVFGTMQLILYGIYRNAKPVGLSNGLSEIAQDEEEGLTSRVEPLLS
InterPro domains: - IPR047664: Sugar transporter SWEET (family) [14-215]
- IPR004316: Sugar transporter SWEET repeat (repeat) [6-213]
Interaction partners: - Sucrose transport protein SUC4
- At2g39500/F12L6.16
- Monosaccharide-sensing protein 2
- Sugar transporter ERD6-like 7
- Sugar transporter ESL1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0042221 (response to chemical), GO:0055085 (transmembrane transport), GO:0051234 (establishment of localization), GO:0051716 (cellular response to stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0006950 (response to stress), GO:0007154 (cell communication), GO:0009266 (response to temperature stimulus), GO:0009991 (response to extracellular stimulus), GO:0044085 (cellular component biogenesis), GO:0042594 (response to starvation), GO:0034486 (vacuolar transmembrane transport), GO:0033554 (cellular response to stress), GO:0006810 (transport), GO:0006970 (response to osmotic stress), GO:0016043 (cellular component organization), GO:1901700 (response to oxygen-containing compound), GO:0031668 (cellular response to extracellular stimulus), GO:0071496 (cellular response to external stimulus), GO:0009409 (response to cold), GO:0010033 (response to organic substance), GO:0034219 (carbohydrate transmembrane transport), GO:0009743 (response to carbohydrate), GO:0009267 (cellular response to starvation), GO:0031667 (response to nutrient levels), GO:0015749 (monosaccharide transmembrane transport), GO:0071702 (organic substance transport), GO:0043933 (protein-containing complex organization), GO:0031669 (cellular response to nutrient levels), GO:0022607 (cellular component assembly), GO:0006995 (cellular response to nitrogen starvation), GO:0008643 (carbohydrate transport), GO:0043562 (cellular response to nitrogen levels), GO:0065003 (protein-containing complex assembly), GO:0008645 (hexose transmembrane transport), GO:0034285 (response to disaccharide), GO:0034284 (response to monosaccharide), GO:0051259 (protein complex oligomerization), GO:0009746 (response to hexose), GO:0009744 (response to sucrose), GO:0051260 (protein homooligomerization), GO:0009750 (response to fructose), GO:0009749 (response to glucose)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0005773 (vacuole), GO:0031090 (organelle membrane), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0000325 (plant-type vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0005774 (vacuolar membrane), GO:0009705 (plant-type vacuole membrane)