wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Killer cell immunoglobulin-like receptor 3DL3 (CD158 antigen-like family member Z) (Killer cell inhibitory receptor 1) (CD antigen CD158z) (Q8N743)
Organism: Homo sapiens (Human)
Function: Receptor on natural killer cells. May inhibit the activity of NK cells thus preventing cell lysis.
Subcellular location: Cell membrane; Single-pass type I membrane protein.
Sequence: MSLMVVSMACVGFFLLEGPWPHVGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVPELYNRIFRNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPVTHGGNYRCFGSFRALPHAWSDPSDPLPVSVTGNSRHLHVLIGTSVVIIPFAILLFFLLHRWCANKKNAVVMDQEPAGNRTVNREDSDEQDPQEVTYAQLNHCVFTQRKITRPSQRPKTPPTDTSV
InterPro domains: - IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [27-317]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [28-319]
- IPR050412: Immunoglobulin-like Receptors in Immune Regulation (family) [23-217]
- IPR013151: Immunoglobulin-like beta-sandwich domain (domain) [35-304]
- IPR003598: Immunoglobulin subtype 2 (domain) [40-102]
- IPR003599: Immunoglobulin domain subtype (domain) [34-325]
Interaction partners: - Killer cell immunoglobulin-like receptor 2DL3
- Killer cell immunoglobulin-like receptor 3DL1
- Killer cell immunoglobulin-like receptor 2DL1
- Killer cell immunoglobulin-like receptor 3DL2
- HLA class I histocompatibility antigen, B alpha chain
- HLA class I histocompatibility antigen, A alpha chain
- Natural killer cells antigen CD94
- HLA class I histocompatibility antigen, alpha chain G
- NKG2-A/NKG2-B type II integral membrane protein
- NKG2-C type II integral membrane protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0005515 (protein binding), GO:0004888 (transmembrane signaling receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0065007 (biological regulation), GO:0048523 (negative regulation of cellular process), GO:0006950 (response to stress), GO:0050794 (regulation of cellular process), GO:0006952 (defense response), GO:0060548 (negative regulation of cell death), GO:0010941 (regulation of cell death), GO:1901214 (regulation of neuron death), GO:1901215 (negative regulation of neuron death), GO:0006968 (cellular defense response)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Cyclin-dependent kinase-like 5 isoform 2 (EC 2.7.11.22) (Zgc:194395 protein) (B3DI12)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Sequence: MKIPDIGNVMNKFEVLGIVGEGAYGVVLKCRHKETKELVAIKKFKDSEENEEVKETTLRELKMLRTLKQDNIVELKEAFRRRGKLYLVFEYVEKNMLELLEELPNGALPDKVRSYIFQLIKAIHWCHKNEIVHRDIKPENLLISANDILKLCDFGFARNLSEGSDANYTEYVATRWYRSPELLLGAPYGKAVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPPEQMKLFYSNPRFAGLRFPSVSHPQTLDRRYLGIINGLMLDLMKNLLCLNPTERFLTEQCLNHPVFQGLRGPEQPAVPSPTPPRSSKRKPYHGDNTIPSRSHGSKSSSHRRANSKDCSSLPRHEDLHRSTDSFLNGTNMPTSSTLSPTLHPKSYQAQTLSRSASSNKDLANNNLPHLLSPKDAKGKTEFDFNLGPKVGVASVGMDTSTGKYLKSSKQGRHSSFLEGKTSTLQSGDKHSRHNYMESSHGSMPSTSSSKSSSSFLSLSKSHGALNDAKSVSNLAETRLHLDDPMAGSGSGSRYFPSSCLDLNAAPGSPRGERHAGTERQGHSPSGRGSNRLEGGTLDSRRSSGRKKTPDEPKPTDTLDPSRAAGGHAHNLPSPHESYPYGLGYTSPFSSQQRPHRHSMYVRRERHRPHGQENNLVVGQGVPTRASSLQLLSPQLQHRTLPRHNTSSSREELTPELSRNDQSPKEKPHSRPLIKDSTRDNTATFHTQRPKNEAGMYHDAHMEDGTSSKENRTIYSDSMPRRVGSFYRVPSPRPDNTFLETTGQSRVQAVAAENPTMTNHSKRQTNFDPWNNSEAMVMNPPEVPKQKEKQGFFRAIKKKKKKSQPVPSETQQDQLVLQRPVKSSSHHSSRHRNRDRERERDMERDRERERDRNRDRDRERDRDNTWPPEKQPEVQPQNQPLKSLRKLLHLSSPATSNQPPPPDRSAELRFQPLPNPPSKANLNEVRGHPAGSVTPNTKSRKPHNYPLPGQIESSWHVSALNRAEGAPYPDQLANKGGQNGIGFTRAARTRMPNLNDLKETAL
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [8-301]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [131-143]
- IPR050108: Cyclin-dependent kinase (family) [10-297]
- IPR017441: Protein kinase, ATP binding site (binding_site) [19-43]
- IPR000719: Protein kinase domain (domain) [13-297]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0004674 (protein serine/threonine kinase activity), GO:0097472 (cyclin-dependent protein kinase activity), GO:0016301 (kinase activity), GO:0004693 (cyclin-dependent protein serine/threonine kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0009790 (embryo development), GO:0048598 (embryonic morphogenesis), GO:0016477 (cell migration), GO:0007369 (gastrulation), GO:0001667 (ameboidal-type cell migration), GO:0042074 (cell migration involved in gastrulation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Anthocyanidin synthase (Gibberellin 3-hydroxylase 1) (Q2QCX4)
Organism: Gossypium hirsutum (Upland cotton) (Gossypium mexicanum)
Function: Not known
Sequence: MVTSVLPRVESLASSGIQSIPKEYIRPQEELTSIGNVFEEEKKEEGPQVPTIDLTEIESEDKEVRERCQQELKKAAMEWGVMHLVNHGISEELMDRVRKVGQKFFELPVEEKEKYANDQSSGNVQGYGSKLANNASGQLEWEDYFFHLIFPEDKRDLSIWPKIPSEYTEVTSEYARQLRGLASKILSALSICLGLEEGRLEKEVGGVEELLLQLKINYYPKCPQPELALGVEAHTDISALTFILHNMVPGLQLFYQGKWVTAKCVPNSIIMHIGDTIEILSNGKFKSILHRGLVNKEKVRISWAVFCEPPKDKIILKPLPETVSETEPPLFPPRTFAQHIEHKLFRKTQDNLSN
InterPro domains: - IPR026992: Non-haem dioxygenase, N-terminal domain (domain) [49-162]
- IPR050295: Plant 2-oxoglutarate-dependent oxidoreductases (family) [30-332]
- IPR005123: Oxoglutarate/iron-dependent dioxygenase domain (domain) [206-309]
- IPR044861: Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain (domain) [214-309]
- IPR027443: Isopenicillin N synthase-like superfamily (homologous_superfamily) [4-352]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen), GO:0016706 (2-oxoglutarate-dependent dioxygenase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0009791 (post-embryonic development), GO:0048316 (seed development), GO:0045165 (cell fate commitment), GO:0090376 (seed trichome differentiation), GO:0048608 (reproductive structure development), GO:0090377 (seed trichome initiation), GO:0009888 (tissue development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0090558 (plant epidermis development), GO:0061458 (reproductive system development), GO:0010026 (trichome differentiation), GO:0010154 (fruit development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Tripartite motif-containing 25 (Q6P7B3)
Organism: Rattus norvegicus (Rat)
Function: Not known
Sequence: MAELFPLAEELSCSICLEPFKEPVTTPCGHNFCRSCLNETWVVQGPPYRCPQCRTVYQVRPQLHKNTVLCAVVEQFLQAEQARTPVDDWIPPTRSAASSSDTQVSCDHCLKEVAVKTCLVCMASFCQEHLRPHIDSPAFQDHPLQPPVRDLLRRKCSRHNRLREMFCPEHGECICHICLVEHKTCSPTILSQASADLENKLRQKLTIMYSHINGASKALEDVKSKQQNVQESMKRKMLQLRQEYLEMKAVIDAAETSSTHKLKEEEKRVYGKLDTIYQVLLKKKNEMQNLKAEVELILAKGDEFEFLEKAAKLQEVSTKPVYIPKIDLDHDLIKGVYQGALDLKSELKLSLKQLQEKKAEEPCNSGNVGDHAQSTSKPTRPAKKTAPDKKTKKTPGAAGAAGAAGAAGAAGPTSYSSSSNKLPTFGAPGQATIPDATLKPNAPQPNSAAVKAKVLENFLTMSRTELLEYFVKVVFDYNTAHNKVALADNYTTASVADGLQHYRSHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGVCYGSMDRQGPESRLGRNPSSWCVEWFNNKISAWHNNMEKTLPSTKATRVGVLLNCDHGFVIFFAVTEKVYLMYKFKVDFTEALYPAFWVFSAGTTLSICSK
InterPro domains: - IPR017907: Zinc finger, RING-type, conserved site (conserved_site) [28-37]
- IPR058030: TRIM8/14/16/25/29/45/65, coiled-coil region (domain) [215-351]
- IPR006574: SPRY-associated (domain) [470-522]
- IPR042753: TRIM25, PRY/SPRY domain (domain) [473-641]
- IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [471-641]
- IPR027370: Zinc finger, RING-type, eukaryotic (domain) [13-51]
- IPR003877: SPRY domain (domain) [523-643]
- IPR003879: Butyrophylin-like, SPRY domain (domain) [469-631]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [5-65]
- IPR001870: B30.2/SPRY domain (domain) [453-643]
- IPR051051: E3 ubiquitin-protein ligase TRIM/RNF (family) [7-632]
- IPR043136: B30.2/SPRY domain superfamily (homologous_superfamily) [447-643]
- IPR001841: Zinc finger, RING-type (domain) [13-54]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0009719 (response to endogenous stimulus), GO:0009991 (response to extracellular stimulus), GO:1901700 (response to oxygen-containing compound), GO:0007584 (response to nutrient), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0014070 (response to organic cyclic compound), GO:0043627 (response to estrogen), GO:0033273 (response to vitamin), GO:0033993 (response to lipid), GO:0031667 (response to nutrient levels), GO:0033280 (response to vitamin D)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: FIG4 phosphoinositide 5-phosphatase (A0A8I6ADY9)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004308}.
Sequence: MPTAAAPIISSVQKLVLYETRARYFLVGSNHAETKFRVLKIDRTEPKDLVVIDDRHVYTQQEVRELLGRLDLGNRTKLSQKGSSGLFRAVSAFGVVGFVRFLEGYYIVLITKRRKMADIGGHAIYKIEDTSMIYIPNDSVRITHPDEARYVYSYDLSHSLQYNLTVLRMPLEMLKSETSKTCQESFDIFEDEGLTTQGGSGVFGISSEPYMKYVWNGELLDIIKNSVHRDWLLYIIHGFCGQSKLLIYGRPVYVTLIARRSSRFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFTAGSYSSYVQVRGSVPLFWSQDISTMMPKPPITLDQADPFAHIAALHFDQMLQRFGSPIIILNLVKEREKRKHERILSEELVAAVTYLNQFLPPEHSIVYIPWDMAKYTKSKLCNVLDRLNVIAESVVKKTGFFVNRPDSYCSVLRPDEKGISLWSEVAQTGILRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFDTDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQDSINLFLGVFHPTEGKPHLWELPTDFYLHHKNTMSLLPPKRSYTHWWTPEVVKHLPLPYDEVICAANLKKLTVKKFHRWEEEIDIHNEFFRPYELSSFDDTFCLAMTSSARDFMPKTIGIDPSPFTVRKPDETGKSVLGNKSNREEAVLQRKTAASAPPPPSEEAVSSSSEDDSGTDREDEGSISQRSTPVKMTDTGDSAKVTESVAQPMKEVYGVSLSRSLSEEDHSIYARFVQLGQSQHRQDWSSPQMCARCSDGVIKLTPISAFSQDNIYEVQPPRVDRKSTEIFQAHIQASQGIMQPLGKEDTAIYREYIRNRYL
InterPro domains: - IPR002013: SAC domain (domain) [93-527]
- IPR043573: Polyphosphoinositide phosphatase Fig4-like (family) [11-780]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0016791 (phosphatase activity), GO:0052866 (phosphatidylinositol phosphate phosphatase activity), GO:0034593 (phosphatidylinositol bisphosphate phosphatase activity), GO:0034595 (phosphatidylinositol phosphate 5-phosphatase activity), GO:0106018 (phosphatidylinositol-3,5-bisphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050794 (regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0033043 (regulation of organelle organization), GO:0044088 (regulation of vacuole organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0044232 (organelle membrane contact site), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0045202 (synapse), GO:0030133 (transport vesicle), GO:0043227 (membrane-bounded organelle), GO:0030658 (transport vesicle membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0012506 (vesicle membrane), GO:0005770 (late endosome), GO:0005769 (early endosome), GO:0030672 (synaptic vesicle membrane), GO:0010008 (endosome membrane), GO:0031982 (vesicle), GO:0030659 (cytoplasmic vesicle membrane), GO:0097708 (intracellular vesicle), GO:0031901 (early endosome membrane), GO:0031902 (late endosome membrane)
Protein: Palmitoyltransferase (EC 2.3.1.225) (Q9VQK9)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Golgi apparatus, trans-Golgi network membrane {ECO:0000256|ARBA:ARBA00004166}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004166}.
Sequence: MFLMTAGTSNFLSAAWRSEAEESKSKENGSLCCCEYVAEDSRERSHILGCCCNCVDFDLVCTRLVTCRAIDRRNIDGMLIAFQDRLRLPWRGGAKRISPAAVAPAFIVPLMLGLATLNSKTAIVLMLTLVGFTIWGMELAKRTATRTNFFLSWLVFSVFYMIIIFEFQVPLLELAPEENYALMFFSCAALYCLYSAKALSPLNLVSAQYGTTPKDELPGIAEASSGEEQAEAQTTLQMESVLSLDDDEVGDMDTAERSGLMHGQPNICEICRKVTPRRAYHCPVCGTCVKRRDHHSYWLNCCIGERNYVWYIVGLALSEIALLLGANLTLTSICHPFMVVRPLGYPVLLPDDCSEVFEGFDLGISFVVACYALLISSYIAFILARQAYLWWKGSTLHEYKRTSNAAGRNRIWSNWRAILK
InterPro domains: - IPR001594: Palmitoyltransferase, DHHC domain (domain) [263-400]
- IPR039859: Palmitoyltransferase PFA4/ZDHHC16/ZDHHC20/ERF2-like (family) [150-415]
Interaction partners: - Beta1,4-N-acetylgalactosaminyltransferase B
- Palmitoyltransferase
- Palmitoyltransferase
- Beta1,4-N-acetylgalactosaminyltransferase A
- Palmitoyltransferase
- Palmitoyltransferase
- Palmitoyltransferase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016409 (palmitoyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0046907 (intracellular transport), GO:0051649 (establishment of localization in cell), GO:0006810 (transport), GO:0006888 (endoplasmic reticulum to Golgi vesicle-mediated transport), GO:0016192 (vesicle-mediated transport), GO:0048193 (Golgi vesicle transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Aquaporin 8b (Aquaporin-8) (C0HB60)
Organism: Salmo salar (Atlantic salmon)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
Sequence: MTEGTMELGDVGTSLMASDSKKAPVKPPNKFERLVQPCLAELVGTMFFVFIGCVSVIENVEAAGRLQPALVHGLAVAVMVACMAEISGSHFNPPFTIAIYLCGGMKLNMVGPYLISQLIGGVLGASMSKLMTTTENYSKAQGAAFALLQSQDQLWGALFGEIAMTCLVTMVVLLGAVNAKSSSPMVPFMVGCTVIINILAGGDVSGTCLNPARALGPAIVANYWTYHWVYWVGPITGGLVAAALVRLLLGDRKTRILMK
InterPro domains: - IPR000425: Major intrinsic protein (family) [35-248]
- IPR034294: Aquaporin transporter (family) [29-249]
- IPR023277: Aquaporin 8 (family) [24-259]
- IPR023271: Aquaporin-like (homologous_superfamily) [9-255]
Interaction partners: - Aquaporin
- Aquaporin
- Aquaporin
- Aquaporin
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0042887 (amide transmembrane transporter activity), GO:1901618 (organic hydroxy compound transmembrane transporter activity), GO:0015144 (carbohydrate transmembrane transporter activity), GO:0005372 (water transmembrane transporter activity), GO:0015166 (polyol transmembrane transporter activity), GO:0015168 (glycerol transmembrane transporter activity), GO:0015267 (channel activity), GO:0015204 (urea transmembrane transporter activity), GO:0015250 (water channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0006950 (response to stress), GO:0009628 (response to abiotic stimulus), GO:0006970 (response to osmotic stress), GO:0009651 (response to salt stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle)
Protein: PLAC domain-containing protein (Q8C9R1)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Sequence: MCVFHGCLFPTIYSIPNPPPSSGHQCNSLPLAGRAGQLASFKANTLAASWTGVQRQEVVCKRLDDNSIVQNNFCDPDSKPPENQRACNTEPCPPEWFIGDWLECSKTCDGGMRTRAVLCIRKVGPSEEETLDYGDCLTHRPVEKESCNNQSCPPQWVALDWSECTPKCGSGFKHRIVLCKSSDLSKTFPAAQCPEESKPPARIRCSLGRCPPPRWVTGDWGQCSAQCGLGQQMRTVQCLSYTGQASVDCPETVRPPSMQQCDSKCDSTPLSSTEECKDVNKVAYCPLVLKFKFCSRAYFRQMCCKTCQGH
InterPro domains: - IPR000884: Thrombospondin type-1 (TSP1) repeat (repeat) [92-266]
- IPR050439: ADAMTS and ADAMTS-like (family) [48-308]
- IPR036383: Thrombospondin type-1 repeat superfamily (homologous_superfamily) [95-285]
- IPR010909: PLAC (domain) [272-310]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0044238 (primary metabolic process), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:1901564 (organonitrogen compound metabolic process), GO:0009888 (tissue development), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0019538 (protein metabolic process), GO:0048513 (animal organ development), GO:0009790 (embryo development), GO:0060711 (labyrinthine layer development), GO:0043170 (macromolecule metabolic process), GO:0035239 (tube morphogenesis), GO:0036211 (protein modification process), GO:0048568 (embryonic organ development), GO:0043412 (macromolecule modification), GO:0048514 (blood vessel morphogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0060674 (placenta blood vessel development), GO:0060716 (labyrinthine layer blood vessel development), GO:0060429 (epithelium development), GO:0001890 (placenta development), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development), GO:0001892 (embryonic placenta development), GO:0001701 (in utero embryonic development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)