wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Protein anon-37Cs (P18487)
Organism: Drosophila melanogaster (Fruit fly)
Function: Has a non-vital function.
Subcellular location: Cytoplasm.
Sequence: MQCFKLASRRSLYNARVLQADNIGDKQRSPDLEAARQNTQIVVVGAGLAGLSAAQHLLSHGFRRTVILEATDRYGGRINTQRFGDTYCELGAKWVKIDGSQDSMYELLRNTEGLGKQIKQPDRATYLQDGSRINPAMVELIDTLFRQLCRGFKVSERVKTGGDLHSLDNVMNYFRTESDRIIGVSFQHPKDQLAAREIFQSLFKEFGSILGCCLEYVNIEHITKCPVQQEQRPLYVPTGLDNVVDDLIQNMDKAQLQTGKPVGQIQWTPAPMKSVGCLDGSLYNADHIICTLPLGVLKSFAGVLFRPTLPLDKMLAIRNLGFGNPLKIYLSYKKPIGRWLKGSLRPLGTLLNPSVEQQPERNWTQQVVEISQVPSSQHVLEVHVGGGYYEEIEKLPDEELLEQITGLLRRCVSSHLVPYPQELLRSNWSTSACYLGGRPYFSTNSSARDVQRLAAPLGEKSPGLLFAGDATSLRGFGTIDAARSSGIREAQRIIDYYLKSVHCG
InterPro domains: - IPR050281: Flavin monoamine oxidase and related enzymes (family) [25-499]
- IPR036188: FAD/NAD(P)-binding domain superfamily (homologous_superfamily) [37-497]
- IPR002937: Amine oxidase (domain) [48-494]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016645 (oxidoreductase activity, acting on the CH-NH group of donors), GO:0016647 (oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901575 (organic substance catabolic process), GO:0009308 (amine metabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0006576 (biogenic amine metabolic process), GO:0009310 (amine catabolic process), GO:0042402 (cellular biogenic amine catabolic process), GO:0006595 (polyamine metabolic process), GO:0006598 (polyamine catabolic process), GO:0008215 (spermine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Rho GTPase-activating protein 8 (Rho-type GTPase-activating protein 8) (P85298)
Organism: Homo sapiens (Human)
Function: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.
Sequence: MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKDGDLTMWPRLVSNSKLKRSSHLSLPKYWDYRYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWEQGSRAAPLQEAVPRTQATGLTKPTLPPSPLMAARRRL
InterPro domains: - IPR000198: Rho GTPase-activating protein domain (domain) [226-412]
- IPR008936: Rho GTPase activation protein (homologous_superfamily) [197-418]
- IPR036865: CRAL-TRIO lipid binding domain superfamily (homologous_superfamily) [14-196]
- IPR001251: CRAL-TRIO lipid binding domain (domain) [13-199]
Interaction partners: - Proline-rich protein 5
- Endophilin-A2
- Endophilin-A3
- Endophilin-A1
- PRR5-ARHGAP8 readthrough
- Cell division control protein 42 homolog
- Transforming protein RhoA
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0008047 (enzyme activator activity), GO:0060589 (nucleoside-triphosphatase regulator activity), GO:0030695 (GTPase regulator activity), GO:0005096 (GTPase activator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0071840 (cellular component organization or biogenesis), GO:0030029 (actin filament-based process), GO:0040017 (positive regulation of locomotion), GO:0040012 (regulation of locomotion), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0016043 (cellular component organization), GO:2000145 (regulation of cell motility), GO:0030036 (actin cytoskeleton organization), GO:2000147 (positive regulation of cell motility), GO:0030335 (positive regulation of cell migration), GO:0030334 (regulation of cell migration), GO:0006996 (organelle organization), GO:0007010 (cytoskeleton organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Vanadium-binding protein 2 (EC 1.13.-.-) (Q86BW2)
Organism: Ascidia sydneiensis samea (Vanadium-rich ascidian)
Function: Acts as a vanadium reductase which may form an electron transfer cascade in conjunction with NADPH and glutathione through thiol disulfide exchange reactions. Partial cleavage of its disulfide bonds results in the reduction of V(5+) to V(4+). Binds up to 24 V(4+) ions per protein at pH 7.5. Also binds Fe(3+) and Cu(2+) and, to a lesser extent, Co(2+), Zn(2+) and Ni(2+).
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17116994}.
Sequence: MSKVIFALVLVVVLVACINATYVEFEEAYAPVDCKGQCTTPCEPLTACKEKCAESCETSADKKTCRRNCKKADCEPQDKVCDACRMKCHKACRAANCASECPKHEHKSDTCRACMKTNCK
InterPro domains: - IPR021544: Vanadium-binding protein 2 (family) [34-119]
- IPR037242: Vanadium-binding protein 2 superfamily (homologous_superfamily) [26-120]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140678 (molecular function inhibitor activity), GO:0061134 (peptidase regulator activity), GO:0004857 (enzyme inhibitor activity), GO:0061135 (endopeptidase regulator activity), GO:0030414 (peptidase inhibitor activity), GO:0004866 (endopeptidase inhibitor activity), GO:0004867 (serine-type endopeptidase inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0035821 (modulation of process of another organism), GO:0044359 (modulation of molecular function in another organism)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Endolysin (LysB4) (H9NAL3)
Organism: Bacillus phage B4
Function: Not known
Sequence: MAMALQTLIDKANRKLNVSGMRKDVADRTRAVITQMHAQGIYICVAQGFRSFAEQNALYAQGRTKPGSIVTNARGGQSNHNYGVAVDLCLYTQDGSDVIWTVEGNFRKVIAAMKAQGFKWGGDWVSFKDYPHFELYDVVGGQKPPADNGGAVDNGGGSGSTGGSGGGSTGGGSTGGGYDSSWFTKETGTFVTNTSIKLRTAPFTSADVIATLPAGSPVNYNGFGIEYDGYVWIRQPRSNGYGYLATGESKGGKRQNYWGTFK
InterPro domains: - IPR003646: SH3-like domain, bacterial-type (domain) [185-252]
- IPR039561: Peptidase M15C (domain) [73-135]
- IPR009045: Peptidase M74/Hedgehog-like, zinc-binding domain superfamily (homologous_superfamily) [4-137]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008234 (cysteine-type peptidase activity), GO:0004175 (endopeptidase activity), GO:0004197 (cysteine-type endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0016032 (viral process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0035821 (modulation of process of another organism), GO:0019058 (viral life cycle), GO:0019076 (viral release from host cell), GO:0044403 (biological process involved in symbiotic interaction), GO:0140975 (disruption of cellular component of another organism), GO:0051701 (biological process involved in interaction with host), GO:0044659 (viral release from host cell by cytolysis), GO:0051673 (disruption of membrane integrity in another organism), GO:0044003 (modulation by symbiont of host process), GO:0052111 (modification by symbiont of host structure), GO:0001907 (killing by symbiont of host cells), GO:0044000 (movement in host), GO:0052043 (modification by symbiont of host cellular component), GO:0001897 (cytolysis by symbiont of host cells), GO:0035891 (exit from host cell), GO:0052025 (modification by symbiont of host cell membrane)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: ERCC excision repair 8, CSA ubiquitin ligase complex subunit (Ercc8 protein) (B1WBX3)
Organism: Rattus norvegicus (Rat)
Function: Not known
Sequence: MFTSSSFDKTLKVWDTNTLQAADVFNFEETVYSHHMSPAATKHCLVAVGTRGPKVQLCDLKSGSCSHILQGHRQEILAVSWSPRYDYILATASADSRVKLWDVRRASGCLLTLDQHNGKKSQAVESANTAHNGKVNGLCFTSDGLHLLTVGTDNRMRLWNSSSGDNTLHHCHVCSLLRRAARHA
InterPro domains: - IPR001680: WD40 repeat (repeat) [1-169]
- IPR019775: WD40 repeat, conserved site (conserved_site) [89-161]
- IPR020472: PAC1/LIS1-like, WD-40 repeat (repeat) [2-161]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [1-181]
- IPR042238: DNA excision repair protein Rad28/ERCC8/Ckn1/ATCSA-1 (family) [1-170]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [2-165]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:0009612 (response to mechanical stimulus), GO:0010996 (response to auditory stimulus), GO:0014070 (response to organic cyclic compound)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Ribosome biogenesis protein NSA1 (Q382X8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MCLVKRGLPQNGGGGGEFVLCCSTFFKRKCCVSMACVTGDDTGLVKVWNISKSTGATLSFSYGEQSRKRGIAGMCWVDSSTTRVAFSMNDGVLSILDLSERAVTLSKKVGVFSALSNSLCSYKGKILVASGSGKVLLTTPVLEAADTIECGGPVEAFHFHRRYGMWSMGGKGNDMCVYDLNSQDVGTPVFRAQNVRDHVLDVPYPVYVTGTCVINPFVFCTTTAYHQVRFYDRRSSERPIQEFEISREIERRPTTLLQWNCNKFLIGEASGDVHLYDTRRGFASRAKLRGGVGSVRSMAKHPSGHQILAVAGLDRKARLYHVPTGKLLMTMYTKQRTTSVLLDKGIPLKDNTAVYSNVANSKQPSKLNGIGDEVWDNMDPVVDDINWQQ
InterPro domains: - IPR037379: WDR74/Nsa1 (family) [29-366]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [13-342]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [36-340]
Interaction partners: - RNA processing factor 1, putative
- Ribosome biogenesis protein BOP1 homolog
- Protein MAK16 homolog
- Pescadillo homolog
- Uncharacterized protein
- Eukaryotic translation initiation factor 6
- Nucleolar GTP-binding protein 1
- rRNA processing protein, putative
- RNA-binding protein, putative
- Ribosome biogenesis protein NSA2 homolog
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0016043 (cellular component organization), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0006259 (DNA metabolic process), GO:0006996 (organelle organization), GO:0090304 (nucleic acid metabolic process), GO:0000723 (telomere maintenance), GO:0051276 (chromosome organization), GO:0032200 (telomere organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Protein UL96 (F5H8R6)
Organism: Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
Function: Not known
Subcellular location: Virion {ECO:0000250}.
Sequence: MTSVNKQLLKDVMRVDLERQQHQFLRRTYGPQHRLTTQQALTVMRVAAREQTRYSQRTTQCVAAHLLEQRAAVQQELQRARQLQSGNVDDALDSLTELKDTVDDVRATLVDSVSATCDLDLEVDDAV
InterPro domains: - IPR022614: Herpesvirus UL96 family (family) [13-101]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0016032 (viral process), GO:0019068 (virion assembly), GO:0046794 (transport of virus), GO:0019058 (viral life cycle), GO:0075733 (intracellular transport of virus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0044423 (virion component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0019033 (viral tegument), GO:0043657 (host cell), GO:0033643 (host cell part), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0039713 (viral factory), GO:0030430 (host cell cytoplasm), GO:0033655 (host cell cytoplasm part), GO:0039714 (cytoplasmic viral factory), GO:0033647 (host intracellular organelle), GO:0033648 (host intracellular membrane-bounded organelle)
Protein: Lys14p (Q5AC02)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MSQSPSSLSPATASSSGVNSPSDQPPLPPRVRKSYSRNGCRECKRRKIRCPEEKPYCSTCVRLGKQCSYPLAGEKVLRISRRLIKEEIENMGKSTQFLPVQYDIPRRIKPQTQSVIKPSPLNIENLINSNDFLNGADLNVLTADLNNLVSDIIEVSNIPILEEDFQFDFLNEPIIVEQITKNVPIDYIKLPRKHEQLYWEEFYNNFAQIIEPFQAYDTKTKKTSNPARDIILQTAATEPFLLAAILAEGANTCYLKYKRPEDERAYGAYLSKCLKLLEPARETDINANIEAVLLTLLLLTAATATSQTQKWRPHLMGAKSLLLKAINQNVSKKFVFCKYWFVSIEILAGLSTNLGGTLQTDAEIDQLVTPGNEFEIEVLRDLGIISDQGFNILMGYDNTCLACFRDLLKILNKKRLNMYIDTMSYVKLLSDFYNQANIVYIDSRGVIAENELTRYVPGLPIEELRINNASYWISWQDISHQSYVLSSLIMILTRFFVIDVSGLVDKVIQFIHYLNQFSDVQQHASPYLLLMIQWPLLVTGLSTTKLEQRHLLLKYFSMVGQIGAAAANVSIQILLKHWKGTIDIENDDTLIY
InterPro domains: - IPR036864: Zn(2)-C6 fungal-type DNA-binding domain superfamily (homologous_superfamily) [30-96]
- IPR021858: Fungal transcription factor (family) [200-579]
- IPR001138: Zn(2)Cys(6) fungal-type DNA-binding domain (domain) [34-81]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0030447 (filamentous growth), GO:0044182 (filamentous growth of a population of unicellular organisms)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Progonadoliberin-1 (Progonadoliberin I) (G1MQ97)
Organism: Meleagris gallopavo (Wild turkey)
Function: Not known
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Sequence: MEKARKISVGVLLFTTSVAICLAQHWSYGLQPGGKRNVENLVESFQEIANEMENLGEAQKAECPGSYQHPSLSNLKETMVSSVDFLLLLWENLRPVQAGKAWGGGV
InterPro domains: - IPR019792: Gonadoliberin (family) [1-85]
- IPR002012: Gonadotropin-releasing hormone (conserved_site) [24-33]
- IPR004079: Gonadoliberin I precursor (family) [24-84]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (signaling receptor activator activity), GO:0048018 (receptor ligand activity), GO:0005179 (hormone activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0065008 (regulation of biological quality), GO:0009628 (response to abiotic stimulus), GO:0050794 (regulation of cellular process), GO:0032350 (regulation of hormone metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0009314 (response to radiation), GO:0010817 (regulation of hormone levels), GO:0009889 (regulation of biosynthetic process), GO:0009416 (response to light stimulus), GO:0046885 (regulation of hormone biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Low-affinity inorganic phosphate transporter PitA (Metal phosphate:H(+) symporter PitA) (P0AFJ7)
Organism: Escherichia coli (strain K12)
Function: Low-affinity inorganic phosphate transporter. Mediates proton-driven uptake of soluble neutral metal phosphate (MeHP04) complexes. It can use Mg(2+), Ca(2+), Co(2+) and Mn(2+). Activity impacts bacterial growth in low Mg(2+) conditions. Is also involved in Zn(2+) uptake, probably via formation of a ZnHPO4 complex. Can also transport arsenate. Involved in the uptake of tellurite.
Subcellular location: Cell inner membrane {ECO:0000269|PubMed:11489853, ECO:0000269|PubMed:15919996}; Multi-pass membrane protein {ECO:0000255}.
Sequence: MLHLFAGLDLHTGLLLLLALAFVLFYEAINGFHDTANAVATVIYTRAMRSQLAVVMAAVFNFLGVLLGGLSVAYAIVHMLPTDLLLNMGSSHGLAMVFSMLLAAIIWNLGTWYFGLPASSSHTLIGAIIGIGLTNALMTGTSVVDALNIPKVLSIFGSLIVSPIVGLVFAGGLIFLLRRYWSGTKKRARIHLTPAEREKKDGKKKPPFWTRIALILSAIGVAFSHGANDGQKGIGLVMLVLIGVAPAGFVVNMNATGYEITRTRDAINNVEAYFEQHPALLKQATGADQLVPAPEAGATQPAEFHCHPSNTINALNRLKGMLTTDVESYDKLSLDQRSQMRRIMLCVSDTIDKVVKMPGVSADDQRLLKKLKSDMLSTIEYAPVWIIMAVALALGIGTMIGWRRVATTIGEKIGKKGMTYAQGMSAQMTAAVSIGLASYTGMPVSTTHVLSSSVAGTMVVDGGGLQRKTVTSILMAWVFTLPAAVLLSGGLYWLSLQFL
InterPro domains: - IPR047818: Inorganic phosphate transporter PitA/PitB (family) [1-498]
- IPR001204: Phosphate transporter (family) [30-497]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0005315 (inorganic phosphate transmembrane transporter activity), GO:0015291 (secondary active transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0098660 (inorganic ion transmembrane transport), GO:0006810 (transport), GO:0098661 (inorganic anion transmembrane transport), GO:0015698 (inorganic anion transport), GO:0006817 (phosphate ion transport), GO:0035435 (phosphate ion transmembrane transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: DNA-(Apurinic or apyrimidinic site) endonuclease (Q564V5)
Organism: Caenorhabditis elegans
Function: Not known
Sequence: MSKRKAEEAPAPKLASIFTKKVKPAEEDNNQKSWKFVCWNVAGLRACVKKSDFKEVLAEEPDLVFLGETKCKEWPPEMEETFKNYTKTLVVSTEKNGGYAGVGLLSKCAPMKVHKGIGDPEFDTAGRLIIAEFSKFYFIGAYVPNSGAKLVNLEKRGRWEKLLTEKMKEMDEKKPVIYGESRIKSK
InterPro domains: - IPR036691: Endonuclease/exonuclease/phosphatase superfamily (homologous_superfamily) [15-179]
- IPR004808: AP endonuclease 1 (family) [24-178]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0140097 (catalytic activity, acting on DNA), GO:0042578 (phosphoric ester hydrolase activity), GO:0003906 (DNA-(apurinic or apyrimidinic site) endonuclease activity), GO:0008081 (phosphoric diester hydrolase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0009791 (post-embryonic development), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0033554 (cellular response to stress), GO:0009790 (embryo development), GO:0002164 (larval development), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0006974 (cellular response to DNA damage stimulus), GO:0006259 (DNA metabolic process), GO:0002119 (nematode larval development), GO:0009792 (embryo development ending in birth or egg hatching), GO:0006281 (DNA repair), GO:0006284 (base-excision repair)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)