Protein: DNA annealing helicase and endonuclease ZRANB3 (E7EXE0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Sequence: MSMKTMKSQGKSAPEEVSLNGKDALQLLPQKLREKLMPFQREGVCFALSRNGRCMIADEMGLGKTIQAISVAYIFKQEWPLLIVVPSSLKYPWIEELEKWIPELDPRDINLVESKTDTMSISTSKVTILGYGLLTTDARALLEALNKQQFAVVLVDESHYLKSRNAARSKILVPIIQSAKRAILLTGTPALGRPEELFMQIDALYPRRFGTWSDYANKYCNAHYRYFGARRQWDCRGASHLDELHKRLSEIMIRRLKNQVLTQLPPKIRQRIPFDLPKDAAKEASASFEQWEKLMSSESENQFVEVMSLITHMYKQTAVAKAGAVKDYIKMMLESEQLKFLVFAHHLSMLQACTEAVIEAKAGYIRIDGSVPSAERIQLVHRFQNDPDTRVAVLSIQAAGQGLTFTAASHVVFAELYWNPGHIKQAEDRAHRIGQTATVHIHYLIAKGTFDTVMWAMLNRKETVTGSALNGKKEYLKAEEGDQEKWDFLNFAQAWTPNQMLKGDSEDDKDGVFFSHFERDKQHDIRSFFSPSVHKEKKRKRTEDSTSDGSPLPQLPAGAEPTQTPETQSFDLTADQGEDFSPQVKRFRQVSPLSRRGGKKSPLSPLFAPRRLSAGLQAPRHNQKWNCSSCTFSNSGLLLRCEMCDSPRNVQKALSPPSSLADPSSSSSLTTICISDSDTENEPSTSSKIQTPHKHPNQQASPNVAETHKDISEEQGSTPKTFNGDSANDDGAYEESGDCVSVYDCLKFCASKNTDRIYIHDKDGLPLHCNFIPLDIRLQNWEELPPEFNHSQNRRQVVRFVREWSSLTAMKQRMVRKSGRVFHSPILLLEELTQSQRRHSSTSRYLSKHDVAQTSIAVAQKEGGALRIINKDSVAFKRTSTSKPADPPNREPESSACVQTDPSAGFLQAVDSSGTPLCLSCQKPSGEQHGWAGGFCSPTCMEDFQLRSSQAYMRARVLEAEQGMCQQCGLNAHQLYLQVRDAPLTHRKDMLDNTWLAQLPLKQLNEMIQSPAEGQFWQVDHIKPVYRGGGQCSLENLQTLCTVCHRMRTAQQVKDRSQMKRNQTASKLASDITRFFVKNETPCNSSKHSNDLHLPTSAGSGAQRVTGHDFNH
InterPro domains: - IPR038718: SNF2-like, N-terminal domain superfamily (homologous_superfamily) [8-276]
- IPR001650: Helicase, C-terminal domain-like (domain) [324-484]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [32-210]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [25-515]
- IPR002711: HNH endonuclease (domain) [1015-1050]
- IPR000330: SNF2, N-terminal (domain) [39-281]
- IPR001876: Zinc finger, RanBP2-type (domain) [620-650]
- IPR036443: Zinc finger, RanBP2-type superfamily (homologous_superfamily) [621-648]
- IPR003615: HNH nuclease (domain) [995-1049]
- IPR049730: SNF2/RAD5-like, C-terminal helicase domain (domain) [316-445]
Interaction partners: - DNA-directed primase/polymerase protein
- Proliferating cell nuclear antigen
- Replication protein A 70 kDa DNA-binding subunit
- Alkylglycerol monooxygenase
- Helicase-like transcription factor
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0048856 (anatomical structure development), GO:0009653 (anatomical structure morphogenesis), GO:0019222 (regulation of metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0009892 (negative regulation of metabolic process), GO:0044237 (cellular metabolic process), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0048523 (negative regulation of cellular process), GO:0044238 (primary metabolic process), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0033554 (cellular response to stress), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0016043 (cellular component organization), GO:0080090 (regulation of primary metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0051052 (regulation of DNA metabolic process), GO:0006974 (cellular response to DNA damage stimulus), GO:0051053 (negative regulation of DNA metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0006259 (DNA metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0006996 (organelle organization), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:0000018 (regulation of DNA recombination), GO:0006281 (DNA repair), GO:0051276 (chromosome organization), GO:0045910 (negative regulation of DNA recombination), GO:0045005 (DNA-templated DNA replication maintenance of fidelity), GO:0006260 (DNA replication), GO:0006275 (regulation of DNA replication), GO:0008156 (negative regulation of DNA replication), GO:0006261 (DNA-templated DNA replication), GO:2000104 (negative regulation of DNA-templated DNA replication), GO:0090329 (regulation of DNA-templated DNA replication), GO:0031297 (replication fork processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)