Protein: Probable glucuronoxylan glucuronosyltransferase F8H (EC 2.4.1.-) (FRA8 homolog) (Protein FRAGILE FIBER 8 homolog) (Q6NMM8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the synthesis of the hemicellulose glucuronoxylan, a major component of secondary cell walls. Probably involved in the synthesis of the glycosyl sequence at the glucuronoxylan reducing end.
Subcellular location: Golgi apparatus membrane {ECO:0000305|PubMed:19224953}; Single-pass type II membrane protein {ECO:0000305|PubMed:19224953}.
Sequence: MSLDIKKPNITKTKKKKTGFVVKMQLNNNRGGNKRNIFIFFFFRNYYTWILWFCLSLYFFTSYFSVEDQSSPSSIRLLSNHKTSSSLPSRALIESSAIKTTSIGLFTGMKIYVYDLPASYNDDWVTASDRCASHLFAAEVAIHRALLSSDVRTLDPDEADYFFVPVYVSCNFSTSNGFPSLSHARSLLSSAVDFLSDHYPFWNRSQGSDHVFVASHDFGACFHAMEDMAIEEGIPKFMKRSIILQTFGVKYKHPCQEVEHVVIPPYIPPESVQKAIEKAPVNGRRDIWAFFRGKMEVNPKNISGRFYSKGVRTAILKKFGGRRRFYLNRHRFAGYRSEIVRSVFCLCPLGWAPWSPRLVESAVLGCVPVVIADGIQLPFSETVQWPEISLTVAEKDVRNLRKVLEHVAATNLSAIQRNLHEPVFKRALLYNVPMKEGDATWHILESLWRKLDDRSYRRSRVLSQREVDM
InterPro domains: - IPR040911: Exostosin, GT47 domain (domain) [108-406]
- IPR004263: Exostosin-like (family) [106-426]
Interaction partners: - Probable beta-1,4-xylosyltransferase IRX14H
- Probable beta-1,4-xylosyltransferase IRX9H
- Beta-1,4-xylosyltransferase IRX14
- Probable galacturonosyltransferase-like 1
- Beta-1,4-xylosyltransferase IRX9
- Probable galacturonosyltransferase 12
- UDP-glucuronate:xylan alpha-glucuronosyltransferase 1
- Putative UDP-glucuronate:xylan alpha-glucuronosyltransferase 4
- UDP-glucuronate:xylan alpha-glucuronosyltransferase 2
- Xylan O-acetyltransferase 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0016757 (glycosyltransferase activity), GO:0016763 (pentosyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0008194 (UDP-glycosyltransferase activity), GO:0015020 (glucuronosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071554 (cell wall organization or biogenesis), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0044036 (cell wall macromolecule metabolic process), GO:0044085 (cellular component biogenesis), GO:1901576 (organic substance biosynthetic process), GO:0042546 (cell wall biogenesis), GO:0044249 (cellular biosynthetic process), GO:0071669 (plant-type cell wall organization or biogenesis), GO:0005975 (carbohydrate metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0044262 (cellular carbohydrate metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:0070589 (cellular component macromolecule biosynthetic process), GO:0016051 (carbohydrate biosynthetic process), GO:0005976 (polysaccharide metabolic process), GO:0034637 (cellular carbohydrate biosynthetic process), GO:0010383 (cell wall polysaccharide metabolic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:0009832 (plant-type cell wall biogenesis), GO:0044038 (cell wall macromolecule biosynthetic process), GO:0044264 (cellular polysaccharide metabolic process), GO:0033692 (cellular polysaccharide biosynthetic process), GO:0000271 (polysaccharide biosynthetic process), GO:0070592 (cell wall polysaccharide biosynthetic process), GO:0009834 (plant-type secondary cell wall biogenesis), GO:0010410 (hemicellulose metabolic process), GO:0045491 (xylan metabolic process), GO:0045492 (xylan biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)