wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Small ribosomal subunit protein uS15 (40S ribosomal protein S13) (Q03334)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P62277}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P62277}.
Sequence: MGRMHAPGKGISQSALPYRRTVPSWLKLNADDVKEQIKKLGKKGLTPSKIGIILRDSHGVAQVRFVNGNKILRIMKSVGLKPDIPEDLYHMIKKAVAIRKHLERNRKDKDGKFRLILVESRIHRLARYYKTKSVLPPNWKYESSTASALVA
InterPro domains: - IPR023029: Small ribosomal subunit protein uS15, archaea/eukaryotes (family) [1-151]
- IPR000589: Small ribosomal subunit protein uS15 (family) [70-149]
- IPR012606: Small ribosomal subunit protein uS15, N-terminal (domain) [1-60]
- IPR009068: uS15/NS1, RNA-binding domain superfamily (homologous_superfamily) [66-142]
Interaction partners: - Small ribosomal subunit protein eS7
- Large ribosomal subunit protein eL24
- Large ribosomal subunit protein uL2
- Ubiquitin-ribosomal protein eS31 fusion protein
- Large ribosomal subunit protein uL22
- Large ribosomal subunit protein eL34
- Small ribosomal subunit protein eS28
- Large ribosomal subunit protein eL15
- Large ribosomal subunit protein eL39
- Large ribosomal subunit protein uL29
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0003735 (structural constituent of ribosome)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0019538 (protein metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006412 (translation), GO:0009059 (macromolecule biosynthetic process), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:0006518 (peptide metabolic process), GO:0010467 (gene expression), GO:0043043 (peptide biosynthetic process), GO:0002181 (cytoplasmic translation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0044391 (ribosomal subunit), GO:0043229 (intracellular organelle), GO:0022626 (cytosolic ribosome), GO:0043228 (non-membrane-bounded organelle), GO:0022627 (cytosolic small ribosomal subunit), GO:0015935 (small ribosomal subunit), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005840 (ribosome)
Protein: Metal transporter CNNM2 (Ancient conserved domain-containing protein 2) (Cyclin-M2) (Q9H8M5)
Organism: Homo sapiens (Human)
Function: Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity).
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Sequence: MIGCGACEPKVKMAGGQAAAALPTWKMAARRSLSARGRGILQAAAGRLLPLLLLSCCCGAGGCAAVGENEETVIIGLRLEDTNDVSFMEGGALRVSERTRVKLRVYGQNINNETWSRIAFTEHERRRHSPGERGLGGPAPPEPDSGPQRCGIRTSDIIILPHIILNRRTSGIIEIEIKPLRKMEKSKSYYLCTSLSTPALGAGGSGSTGGAVGGKGGSGVAGLPPPPWAETTWIYHDGEDTKMIVGEEKKFLLPFWLQVIFISLLLCLSGMFSGLNLGLMALDPMELRIVQNCGTEKEKNYAKRIEPVRRQGNYLLCSLLLGNVLVNTTLTILLDDIAGSGLVAVVVSTIGIVIFGEIVPQAICSRHGLAVGANTIFLTKFFMMMTFPASYPVSKLLDCVLGQEIGTVYNREKLLEMLRVTDPYNDLVKEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSEILDETDLYTDNRTKKKVAHRERKQDFSAFKQTDSEMKVKISPQLLLAMHRFLATEVEAFSPSQMSEKILLRLLKHPNVIQELKYDEKNKKAPEYYLYQRNKPVDYFVLILQGKVEVEAGKEGMKFEASAFSYYGVMALTASPVPLSLSRTFVVSRTELLAAGSPGENKSPPRPCGLNHSDSLSRSDRIDAVTPTLGSSNNQLNSSLLQVYIPDYSVRALSDLQFVKISRQQYQNALMASRMDKTPQSSDSENTKIELTLTELHDGLPDETANLLNEQNCVTHSKANHSLHNEGAI
InterPro domains: - IPR044751: Ion transporter-like, CBS domain (domain) [445-574]
- IPR014710: RmlC-like jelly roll fold (homologous_superfamily) [609-827]
- IPR045095: Ancient conserved domain protein family (family) [170-834]
- IPR002550: CNNM, transmembrane domain (domain) [251-431]
- IPR057492: Metal transporter CNNM1/2/4, immunoglobulin-like domain (domain) [73-249]
- IPR046342: CBS domain superfamily (homologous_superfamily) [429-584]
- IPR000644: CBS domain (domain) [518-584]
Interaction partners: - Protein tyrosine phosphatase type IVA 1
- Arsenite methyltransferase methyltransferase)
- Cystathionine beta-synthase
- Protein tyrosine phosphatase type IVA 2
- Cytosolic purine 5'-nucleotidase
- Cystathionine beta-synthase-like protein
- Solute carrier family 41 member 1
- Transient receptor potential cation channel subfamily M member 6
- StAR-related lipid transfer protein 13
- Magnesium transporter NIPA3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0006811 (monoatomic ion transport), GO:0006812 (monoatomic cation transport), GO:0030001 (metal ion transport), GO:0015693 (magnesium ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex)
Protein: Phosphatidate cytidylyltransferase (EC 2.7.7.41) (CDP-DAG synthase) (CDP-DG synthase) (CDP-diacylglycerol synthase) (CDS) (CDP-diglyceride pyrophosphorylase) (CDP-diglyceride synthase) (CTP:phosphatidate cytidylyltransferase) (P9WPF7)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Not known
Subcellular location: Cell membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
Sequence: MSWLNTKKASCWRSSGRSATKSVTTNDAGTGNPAEQPARGAKQQPATETSRAGRDLRAAIVVGLSIGLVLIAVLVFVPRVWVAIVAVATLVATHEVVRRLREAGYLIPVIPLLIGGQAAVWLTWPFGAVGALAGFGGMVVVCMIWRLFMQDSVTRPTTGGAPSPGNYLSDVSATVFLAVWVPLFCSFGAMLVYPENGSGWVFCMMIAVIASDVGGYAVGVLFGKHPMVPTISPKKSWEGFAGSLVCGITATIITATFLVGKTPWIGALLGVLFVLTTALGDLVESQVKRDLGIKDMGRLLPGHGGLMDRLDGILPSAVAAWIVLTLLP
InterPro domains: - IPR000374: Phosphatidate cytidylyltransferase (family) [285-311]
Interaction partners: - Probable phosphatidylglycerophosphate synthase
- 1-acylglycerol-3-phosphate O-acyltransferase
- Phosphatidylinositol phosphate synthase
- Diacylglycerol kinase
- CDP-diacylglycerol--serine O-phosphatidyltransferase
- Putative cardiolipin synthase
- Probable CDP-diacylglycerol pyrophosphatase
- Uridylate kinase
- Ribosome-recycling factor
- Decaprenyl diphosphate synthase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:1903509 (liposaccharide metabolic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0046467 (membrane lipid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0006643 (membrane lipid metabolic process), GO:0009247 (glycolipid biosynthetic process), GO:0006664 (glycolipid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Alpha-1,3-arabinosyltransferase XAT3 (EC 2.4.2.-) (Xylan arabinosyltransferase 3) (OsXAT3) (Q10I20)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Glycosyltransferase involved in the arabinosylation of xylan, the major hemicellulose (non-cellulosic component) of primary and secondary walls of angiosperms. Possesses alpha-1,3-arabinosyltransferase activity, transferring an arabinofuranose residue to the xylan backbone.
Subcellular location: Golgi apparatus membrane {ECO:0000305|PubMed:22215597}; Single-pass type II membrane protein {ECO:0000255}.
Sequence: MKAGERPKLVRGVRQESRRFRLLVIVVGFFLVSLTFVFVSKPDAILFSLNGKLPVEQAPTSILIQQKVNEPSGESRKTSTDALRGDPKVVDDEADAKPKGTGGGSEEEEGRVLSEPDPTSGMMEPTHNKDGNGHKSHQETLGGGGDGESKGNDEEGEHAEQKHKVTLPTVSNYTIHDAAEDTENAKQEGMNNVQQGSKPLCDFSNFRANVCEMRGDVRIHPTATSVLFMEPEGSQRDEVWKIKPYPRKGDEFCLSHITEVTVKSSKVAPECTKYHDVPAVIFSLTGYTGNLFHDFTDVLVPLFTTASEFNGEVQFLITDMALWWTIKYQTVLQKLSKYPVIDFSKDDQVHCFKHAIVGLHAYMEFTIDSTKAPHNYSMADFNRFMRGAYSLGRDSVTVLGEYPKIKPRLLIIKRHRTRMFLNLDEIISMAEELGFEVVIDEANVSSDISRFARLVNSVDVMMGVHGAGLTNCVFLPQHATLIQIVPWGGLDWISRTDFGNPAELMGLRYKQYSIGVDESSLTDQYPRDHEIFKNPISFHQRGFDFIRQTFMDKQNVKLDCKRFRPILLEALDNLNP
InterPro domains: - IPR049625: Glycosyltransferase 61, catalytic domain (domain) [396-482]
- IPR007657: Glycosyltransferase 61 (family) [17-574]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016763 (pentosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0071554 (cell wall organization or biogenesis), GO:0071555 (cell wall organization), GO:0016043 (cellular component organization), GO:0071669 (plant-type cell wall organization or biogenesis), GO:0045229 (external encapsulating structure organization), GO:0009664 (plant-type cell wall organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0016020 (membrane), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0000139 (Golgi membrane), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Palmitoyltransferase (EC 2.3.1.225) (Q2THW6)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Golgi apparatus membrane {ECO:0000256|ARBA:ARBA00004653}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004653}. Mitochondrion membrane {ECO:0000256|ARBA:ARBA00004225}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004225}.
Sequence: MPRSPGTRLKPAKYIPVATAAALLVGSSTLFFVFTCPWLTRAVSPAIPVYNGILFLFVLANFSMATFMDPGVFPRADEDEDKEDDFRAPLYKNVDVRGIQVRMKWCATCHFYRPPRCSHCSVCDNCVEDFDHHCPWVNNCIGRRNYRYFFLFLLSLSAHMVGVVAFGLLYVLNHSEGLGAAHTTITMAVMCVAGLFFIPVIGLTGFHVVLVTRGRTTNEQVTGKFRGGVNPFTRGCYGNVEHVLCSPLAPRYVVEAPRMPLSVSLKPPFLRPELLERAVPLKVKLSDNGLKAGRSKSKGSLDQLDEKPLDLGPPLPPKMEAGTFGRDLKTPRPGSAESALSVQRTSPPTPAMYKFRPAFSTAPKTPFCGPSEQVPGPDSLTLADDSTHSLDFVSEPSLDLPDHGPGGLHPTYPPSPPLSATDAFSGALRSLSLKAASRRGGDHMTLQPLRSEGGPPTPHRGLFAPHALPNRNGSLSYDSLLNPGSPSGHACPTHPSVGMAGYHSPYLHPGPSDPPRPPPRSFSPVLGPRPREPSPVRYDNLSRTIMASIQERKDREERERLLRSQTDSLFGDSGVYDTPSSYSLQQASVLTEGPRGSVLRYGSRDDLVAGPGFGGARNPALQTSLSSLSSSMSRAPRTSSSSLQADQANNNAPGPRPGSGSHRSPARQGLPSPPGTPRSPSYSGSKAVAFIHTDLPDRQPSLAMQRDHPQLKTPPSKLNGQSPGMARLGPAASPMGPNASPARHTLVKKVSGVGGTTYEISV
InterPro domains: - IPR001594: Palmitoyltransferase, DHHC domain (domain) [102-222]
Interaction partners: - P-type phospholipid transporter
- Large ribosomal subunit protein mL40
- Transport and golgi organization 2 homolog
- Catechol O-methyltransferase
- Proline dehydrogenase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016746 (acyltransferase activity), GO:0019707 (protein-cysteine S-acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0019706 (protein-cysteine S-palmitoyltransferase activity), GO:0016417 (S-acyltransferase activity), GO:0016409 (palmitoyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0065008 (regulation of biological quality), GO:0099072 (regulation of postsynaptic membrane neurotransmitter receptor levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction), GO:0045202 (synapse)
Protein: Neuropeptides B/W receptor type 1 (G-protein coupled receptor 7) (Q8MJV3)
Organism: Bos taurus (Bovine)
Function: Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals (By similarity).
Subcellular location: Cell membrane; Multi-pass membrane protein.
Sequence: MHNASYWGPERANTSCPAPAPTLGCPNASGPAPPLPPPLAVAVPVVYAVICAVGLAGNSAVLFVLLRAPRRKTVTNLFILNLAVADELFTLVPPVNIADFLLRRWPFGELLCKLVVAVDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYGAARAVSLAVWGVATLVVLPFAVFARLDEEQGRRQCVLVFPQPEALWWRASRLYTLVLGFAIPVSTICVLYTSLLCRLRAIRLDSHAKALDRAKKRVTVLVVAILAVCLLVWTPYHLSTVVALTTDLPQTPLVIAVSYFITSLSYANSCLNPFLYAFLDDSFRRSLRQLLACRTTS
InterPro domains: - IPR009150: Neuropeptide B/W receptor family (family) [86-278]
- IPR017452: GPCR, rhodopsin-like, 7TM (domain) [57-310]
- IPR000276: G protein-coupled receptor, rhodopsin-like (family) [42-318]
Interaction partners: - Neuropeptide B
- Neuropeptides B/W receptor type 2
- Prepronociceptin
- Uncharacterized protein.
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0033218 (amide binding), GO:0042277 (peptide binding), GO:0004888 (transmembrane signaling receptor activity), GO:0001653 (peptide receptor activity), GO:0042923 (neuropeptide binding), GO:0008528 (G protein-coupled peptide receptor activity), GO:0004930 (G protein-coupled receptor activity), GO:0008188 (neuropeptide receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007186 (G protein-coupled receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Basic helix-loop-helix (BHLH) DNA-binding superfamily protein (F4K9L3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MELPQPRPFKTQEFRTGRKPTHDFLSLCSHSTVHPDPKPTPPPSSQGSHLKTHDFLQPLECVGAKEDVSRINSTTTASEKPPPPAPPPPLQHVLPGGIGTYTISPIPYFHHHHQRIPKPELSPPMMFNANERNVLDENSNSNCSSYAAASSGFTLWDESASGKKGQTRKENSVGERVNMRADVAATVGQWPVAERRSQSLTNNHMSGFSSLSSSQGSVLKSQSFMDMIRSAKGSSQEDDLDDEEDFIMKKESSSTSQSHRVDLRVKADVRGSPNDQKLNTPRSKHSATEQRRRSKINDRFQMLRQLIPNSDQKRDKASFLLEVIEYIQFLQEKADKYVTSYQGWNHEPAKLLNWSNNNQQLVPEGVAFAPKLEEEKNNIPVSVLATAQGVVIDHPTTATTSPFPLSIQSNSFFSPVIAGNPVPQFHARVASSEAVEPSPSSRSQKEEEDEEVLEGNIRISSVYSQGLVKTLREALENSGVDLTKASISVEIELAKQSSSSSFKDHEVREPVSRTRNDNVKQTRKPKRLKTGQ
InterPro domains: - IPR011598: Myc-type, basic helix-loop-helix (bHLH) domain (domain) [280-336]
- IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [278-351]
- IPR044295: Transcription factor BIM1/2/3 (family) [16-530]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Focal adhesion kinase targeting (FAT) domain-containing protein (G1NJW1)
Organism: Meleagris gallopavo (Wild turkey)
Function: Not known
Sequence: MSSKIQPAPPEEYVPMVKEVGLALRTLLATVDESLPVLPASTHREIEMAQKLLNSDLAELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMISQSRPH
InterPro domains: - IPR036137: Focal adhesion kinase, targeting (FAT) domain superfamily (homologous_superfamily) [1-109]
- IPR005189: Focal adhesion kinase, targeting (FAT) domain (domain) [1-108]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0060322 (head development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007420 (brain development), GO:0007417 (central nervous system development), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Elongation factor 1-alpha 2 (EF-1-alpha-2) (EC 3.6.5.-) (Eukaryotic elongation factor 1 A-2) (eEF1A-2) (Statin-S1) (Q71V39)
Organism: Oryctolagus cuniculus (Rabbit)
Function: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q05639}.
Sequence: MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYNPATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGVSLLEALDTILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRPGMVVTFAPVNITTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDIRRGNVCGDSKSDPPQEAAQFTSQVIILNHPGQISAGYSPVIDCHTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGKPMCVESFSQYPPLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKSAQKAQKAGK
InterPro domains: - IPR050100: Translation factor GTPase superfamily members (family) [1-445]
- IPR004161: Translation elongation factor EFTu-like, domain 2 (domain) [260-326]
- IPR004539: Translation elongation factor EF1A, eukaryotic/archaeal (family) [1-444]
- IPR054696: GTP-eEF1A, C-terminal domain (domain) [339-439]
- IPR000795: Translational (tr)-type GTP-binding domain (domain) [5-242]
- IPR009001: Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal (homologous_superfamily) [338-441]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [1-261]
- IPR009000: Translation protein, beta-barrel domain superfamily (homologous_superfamily) [238-334]
- IPR031157: Tr-type G domain, conserved site (conserved_site) [61-76]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0000166 (nucleotide binding), GO:1901265 (nucleoside phosphate binding), GO:0017076 (purine nucleotide binding), GO:0019001 (guanyl nucleotide binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0007017 (microtubule-based process), GO:0051716 (cellular response to stimulus), GO:0050794 (regulation of cellular process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0035556 (intracellular signal transduction), GO:0019932 (second-messenger-mediated signaling), GO:0019722 (calcium-mediated signaling)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)