Protein: Histone acetyltransferase GCN5 (EC 2.3.1.48) (O76216)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MSGGPSITIKSQPIDGNNTGNAAAQQQQQAANGAATAGASGAAGSAQNPGHGGAASGAGSVPAEGTRQNSLQRIQQRKQKVFNLPVPQKLAKLSMYSACQSEGCRCTGWKTPQENRHRDVESSYCPEFNEECRNTSCRHSLRSHIAHLDNISSSSMNELLGAIIDMENLFMSMQRVEDEDTKKVYQYLFRLLRQCVLTRQQAVIRGPLGDPPFETPCITKAVLSLVFYKYNHLSTPELQTMTEVAKTFLNFLNHYNFESPSTRRGDLTHEDASNYKINYTRWLVFCHVPAFCNSLRQCETSLVFGRTLLRTVFQCVSQQLKKKCISERDRFPEDKRSIITLMPKFLETLRAELLKDDSPIWDTSYRPSNSFVIQQRKRNQEVASVPIGPSAASIGGNKRTSVGEPLHKRIKKEPTDRPSSENLDDLPADVVMRAMKSVSESKTTNKAEILFPVNVSRDENVKAEEQKRAIEFHVVGNSLTKPVDKQTVLWLLGLQLVFAYQLPEMPREYISQLVFDTKHKTLALIKENQPIGGICFRPFPSQGFTEIVFCAVTMSEQVKGYGTHLMNHLKDYSIQRGIKHLLTFADCDAIGYFKKQGFSKDVKLARPVYAGYIKEYDSATLMHCELHPSIVNTQFIAVIRSQSEILKELIAQRHNEVQKVRPGLTCFKEGLPVIPVESIPGLREIGWKPQNRPARSSRPLEESTDPEKLATSFASVLQSVRQHTTAWPFLRPVTAAEVPDYYDHIKYPMDLKTMGERLKKGYYQTRRLFMADMARIFSNCRFYNSPDTEYYRCANSLERYFQTKMRELGLWDK
InterPro domains: - IPR016376: Histone acetyltransferase GCN5/PCAF (family) [1-813]
- IPR009464: PCAF, N-terminal (domain) [73-323]
- IPR000182: GNAT domain (domain) [481-627]
- IPR018359: Bromodomain, conserved site (conserved_site) [726-783]
- IPR037800: Histone acetyltransferase GCN5 (family) [39-809]
- IPR016181: Acyl-CoA N-acyltransferase (homologous_superfamily) [495-627]
- IPR036427: Bromodomain-like superfamily (homologous_superfamily) [686-810]
- IPR001487: Bromodomain (domain) [702-810]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0003682 (chromatin binding), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0061733 (peptide-lysine-N-acetyltransferase activity), GO:0016746 (acyltransferase activity), GO:0004402 (histone acetyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016407 (acetyltransferase activity), GO:0016410 (N-acyltransferase activity), GO:0010484 (histone H3 acetyltransferase activity), GO:0010485 (histone H4 acetyltransferase activity), GO:0008080 (N-acetyltransferase activity), GO:0034212 (peptide N-acetyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006325 (chromatin organization), GO:0006338 (chromatin remodeling)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:0140535 (intracellular protein-containing complex), GO:0098687 (chromosomal region), GO:1902494 (catalytic complex), GO:0005703 (polytene chromosome puff), GO:0031248 (protein acetyltransferase complex), GO:1990234 (transferase complex), GO:1905368 (peptidase complex), GO:0043229 (intracellular organelle), GO:0000123 (histone acetyltransferase complex), GO:0043228 (non-membrane-bounded organelle), GO:0043227 (membrane-bounded organelle), GO:0070461 (SAGA-type complex), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:1902493 (acetyltransferase complex), GO:0070775 (H3 histone acetyltransferase complex), GO:0000124 (SAGA complex), GO:0005634 (nucleus), GO:0140672 (ATAC complex), GO:0005694 (chromosome), GO:0005700 (polytene chromosome)