Protein: Phytyl ester synthase 1, chloroplastic (EC 2.3.1.-) (Q9ZVN2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acyltransferase involved in fatty acid phytyl ester synthesis in chloroplasts, a process required for the maintenance of the photosynthetic membrane integrity during abiotic stress and senescence. Exhibits phytyl ester synthesis and diacylglycerol acyltransferase activities with broad substrate specificities, and can employ acyl-CoAs, acyl carrier proteins, and galactolipids as acyl donors.
Subcellular location: Plastid, chloroplast, plastoglobule {ECO:0000269|PubMed:16461379, ECO:0000269|PubMed:22274653, ECO:0000269|PubMed:22623494}.
Sequence: MATCSSSLLVLPNLRLSSNQRRNFKVRAQISGENKKATSLEPVNNNGSVSLSTTVQNQKGANEVNGKGKSKRKIVSDEIELLWDDGYGSKSVKDYFAAAKEILKADGGPPRWFSPVDCGRPVEDAPTLLFLPGMDGTGMGLVPHHKALGKAFHVSCLHIPVLDRTPFEGLLKVVEDVLRQEQATRPNKPIYLVGDSFGGCLALAVAARNRSLDLVLILVNPATSFDRSPLQPLLPILEMVPEELHFTVPYALSFIMGDPIKMATLGIDNQLPTGVKIEKLRQRLTKTMLPLLSELGGIIPRETLLWKLKLLRSGCAYANSRIHAVQAEVLVLASGKDMMLPSQEEAKRLHGLLKNCSVRCFKDNGHTLLLEDSISLLTVIKGTGKYRRSWRYDLVSDFLPPSKGELAYALDEVLGFLRNAVGSVFFSTMEDGKIVKGLAGVPDKGPVLLVGYHMLMGLELGPMSEAFIKEKNILFRGMAHPVLYSDNDPAKAFDYGDWIKVFGAYPVTATNLFKLLDSKSHVLLFPGGAREALHNRGEQYKLIWPEQQEFVRMAARFGATIVPFGTVGEDDIAELVLDYNDLMKIPILNDYITEVTRDTKQFKLREESEGEVANQPLYLPGLIPKVPGRFYYLFGKPIETKGRPELVKDKEEANQVYLEVKAEVENSIAYLLKKREEDPYRSVLDRLNYSLTHTTATHVPSFEP
InterPro domains: - IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [116-377]
- IPR007130: Diacylglycerol acyltransferase (family) [499-576]
Interaction partners: - Tocopherol cyclase, chloroplastic
- Alternative NAD
- Probable plastid-lipid-associated protein 1, chloroplastic
- Acyl carrier protein 1, mitochondrial
- Probable plastid-lipid-associated protein 3, chloroplastic
- F16N3.9 protein
- Phytol kinase 1, chloroplastic
- Probable plastid-lipid-associated protein 4, chloroplastic
- Glycerol-3-phosphate dehydrogenase [NAD
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0008374 (O-acyltransferase activity), GO:0016411 (acylglycerol O-acyltransferase activity), GO:0004144 (diacylglycerol O-acyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0009605 (response to external stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0090693 (plant organ senescence), GO:0071704 (organic substance metabolic process), GO:0007154 (cell communication), GO:0044238 (primary metabolic process), GO:0009991 (response to extracellular stimulus), GO:1901615 (organic hydroxy compound metabolic process), GO:0099402 (plant organ development), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0042594 (response to starvation), GO:0033554 (cellular response to stress), GO:0048731 (system development), GO:0009889 (regulation of biosynthetic process), GO:0062012 (regulation of small molecule metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0006066 (alcohol metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0044249 (cellular biosynthetic process), GO:0031668 (cellular response to extracellular stimulus), GO:0080090 (regulation of primary metabolic process), GO:0071496 (cellular response to external stimulus), GO:0046460 (neutral lipid biosynthetic process), GO:0006720 (isoprenoid metabolic process), GO:0046486 (glycerolipid metabolic process), GO:0019747 (regulation of isoprenoid metabolic process), GO:0009267 (cellular response to starvation), GO:0031667 (response to nutrient levels), GO:0090207 (regulation of triglyceride metabolic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0034308 (primary alcohol metabolic process), GO:1902930 (regulation of alcohol biosynthetic process), GO:0006638 (neutral lipid metabolic process), GO:1901568 (fatty acid derivative metabolic process), GO:0019216 (regulation of lipid metabolic process), GO:0031669 (cellular response to nutrient levels), GO:0008610 (lipid biosynthetic process), GO:0045017 (glycerolipid biosynthetic process), GO:0046890 (regulation of lipid biosynthetic process), GO:0046463 (acylglycerol biosynthetic process), GO:0006995 (cellular response to nitrogen starvation), GO:0043562 (cellular response to nitrogen levels), GO:0010866 (regulation of triglyceride biosynthetic process), GO:0006721 (terpenoid metabolic process), GO:0006639 (acylglycerol metabolic process), GO:0016101 (diterpenoid metabolic process), GO:0006641 (triglyceride metabolic process), GO:0019432 (triglyceride biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009532 (plastid stroma), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0010287 (plastoglobule), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009570 (chloroplast stroma), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle)