Protein: Host cell factor 1 (A0A8M3AXL2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm. Nucleus
Sequence: MTSPGVPGTTGAPLQPRWKRVLGWSGPVPRPRHGHRAVAIKELMVVFGGGNEGIVDELHVYNTATNQWFIPAVRGDIPPGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEWKKLKPKAPKNGVPPCPRLGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYTLELRPGSSVAGWDVPVTYGVLPPPRESHTAVIYTEKVTKKSRLVIYGGMSGCRLGDLWTLDIDTLTWNKPAISGAAPLPRSLHSATTITNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLNLDTLAWETVLMDTLEDNIPRARAGHCAVAINNRLYIWSGRDGYRKAWNNQVCCKDLWYLETERPNPPSRVQLVRANTNSLEVSWGAVSTADTYLLQLQKYDIPAATAATSPALNAAPSLPGNSPKSPAPAAAAPSAQSLPHSGITSVPQAASPTASVLPGTPASPLAASMARGPAILKVAAPQSGTGASIVTVRQASQVGKSPVTVASLPAGVRMVVPSQTAQGTPIGSSPQMSGMAALAAAAAATQKIPPSPGATVLNMPAGATIVKTVAVTPGASTLPTTVKVASPLMVSNPATRMLKTAAAQVATPTVSSPTTGARPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPLSMGGNLISNLGKVVSVVQNKPVQSATVTGQASNPLTQIIQTKGPLPPGTILKLVTSADGKPTTIITTSQAGGTGNKPTILGISGMSPTSTSKPGTTTIIKTIPMSAVQQGAAGVTSTTGVKSPITIITTKVMTSGTPGKIITAMPKIGTAAGQQGLTQVVLKGAPGQPGTILRTVPMGGVRLVSPVSGVKPTVTTLVVKGTTGVTTLGTVTGTVSSSLAGGSLASANATLATPITTLGTIATLASQVINATNVTAAQSNLTTVTSTMQPTQVTLITTPSGVEAQPGQDLPVSFLASPTSEQPTSTESGTGEASGSVTLVCSNPPCETHETGTTNTATTATSNMGAGPAGTVQRVCSNPPCETHETGTTNTATTASANMGAVQRVCSNPPCETHETGTTSTTTTASSNMGTAPAGTVQRVCSNPPCETHETGTTNTATTASSNMGGNQPGAVQRVCSNPPCETHETGTTNTATTASSSMGGGQEGTVQRVCSNPPCETHETGTTNTATTSSSNMGGDQAGAVQRVCSNPPCETHETGTTNTATTATCNMETDEGTAQQTSEASESSTSTSTESLPATAAAQRGAITTVTQATPLPGPAVPSISSITESSSEAGAEPVVMESSEAESLQTEGQAEAEAVAMQAEFQTEAGAVALPTDFQEDAAALPADFQGEAVAVAMQAESQADAVPMEQDVSGMAEGEAAQEQLPTAEMEDVDAASASQAAVLALPPELMADGQSTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMSDAGGDDQQTHTIPIVLTQQELAALVQQQQQLQAAQQQAAAQAALPTEGLAPADSLNDPLSESNGHNEMAAAATSAVVTLLPRTAAETLAPSSTLAPVVVASPAKMQAAAALTEVANGIEAGKQNPPTVTVKPQVKKENQWFDVGIVKVTNTVVTHFYMPADDSAYVENDSGTAPDYSQMKRVELQPGTAYKFRVAGINTCGRGTFSEISAFKTCLPGFPGAPCAIKISKSPDGAHLTWEPPSVTSGKITEYSVYLAIQSSQTTEAKPSAPAQLAFMRVYCGPNPSCLVQSSSLSNAHIDYTTKPAIIFRIAARNEKGYGPATQVRWLQESSKDGLSAKPAPKRAVSSPDTKGIGQKKARMDQ
InterPro domains: - IPR059124: Host cell factor, Kelch-repeats domain (domain) [15-359]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [359-1766]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [1573-1784]
- IPR003961: Fibronectin type III (domain) [363-1773]
- IPR015915: Kelch-type beta-propeller (homologous_superfamily) [12-361]
- IPR043536: Host cell factor (family) [5-1071]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003682 (chromatin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0016032 (viral process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0019222 (regulation of metabolic process), GO:0071684 (organism emergence from protective structure), GO:0060255 (regulation of macromolecule metabolic process), GO:0001824 (blastocyst development), GO:0009790 (embryo development), GO:0035188 (hatching), GO:0010468 (regulation of gene expression), GO:0009792 (embryo development ending in birth or egg hatching), GO:0001835 (blastocyst hatching), GO:0043009 (chordate embryonic development), GO:0001701 (in utero embryonic development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0043229 (intracellular organelle), GO:0031012 (extracellular matrix), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0062023 (collagen-containing extracellular matrix), GO:0005634 (nucleus)