Protein: RhoGEF Scd1 (B6JVU8)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Sequence: MQQDRKFSSKSVPSDLFRVKSSQDPQVVRTQSHHIQPQQPRANSYSSASAFFSKTSLFQQCRLIVQNLQRVEGFEEAFKAADRLILDFPMRIIRIRDLVEHDPVTQVWNMCCLGFPLCALLNAFQLETPLQVNLDTTLSNTNACKASLYHFLLTCKKDLSLVDADLFTISEIFQDNTASLAKAAHTVSLILDMLDEKGLLRKSVSRDSPLEQASTLSLLIQSSQRVYAELLETEMKYVQDLEFLSDYVAMLQAEHILSQATIQQVFSNLNELLDFQRRFLIGLEMNAIMPASEQRLGALLLQMEDGFSPKVRASRPLLIKPIQRICKYPLLVRELLKGTAPGYRYEEELRQGLECIVRVANKVNENRRRHENNAALVELENRIIDWKGYSLKHFGSLLVWEIVPVAKGDMEREYYVYLFETILLCCKEISPLKKQARNMSINRKLKRQDSLQLKGRIFISNITMIAPNSAYGQHALHIFWNGDSHQESFVLKLRNAESFKQWYFVLKRLLSKKSSSSGNRQSSGSTSTVPSSLGTFRVSRDEDANSQSTFTSRENEQDCGSPSSLVPSSSTQDGDDANSSQYTLLSSQHNPYSVKDASVSLMSSIGSYNNRNSPSFLPSMGPLSDDGARSVSQLHKTPSSSEHSFINNVFSNTATDASATNHAAPSQSFFTGSQPDLSVADYAYQRSGRLPSNSHLSADNRSVSTTTATGSSSPKRHSRQRSFSNPALSVSRPLRESLQSGDLESICSGDSATGKGTNTVKVRIKYEESCLVLLVPAQIGYQELNEKISHKLLVCGLLNMPEDTPIRLRMKYVDEDGDLITITSDEDVFMAFEYCVFEMFNRDGKDGIYCIDLFTSLAP
InterPro domains: - IPR011993: PH-like domain superfamily (homologous_superfamily) [372-522]
- IPR000270: PB1 domain (domain) [759-858]
- IPR000219: Dbl homology domain (domain) [222-366]
- IPR033511: Rho guanine nucleotide exchange factor Cdc24/Scd1, PH domain (domain) [368-503]
- IPR001849: Pleckstrin homology domain (domain) [390-513]
- IPR010481: Cdc24/Scd1, N-terminal (domain) [102-191]
- IPR053793: PB1-like domain (domain) [757-844]
- IPR053026: CDC42 guanine nucleotide exchange factor (family) [315-855]
- IPR035899: Dbl homology (DH) domain superfamily (homologous_superfamily) [215-387]
Interaction partners: - Scaffold protein Scd2
- Rho family GTPase Cdc42
- GTPase Ras1
- Heterotrimeric G protein beta subunit Git5
- Rho-type GTPase activating protein Rga4
- Rho-type GTPase activating protein Rga3
- RhoGEF Gef1
- Rho family GTPase Rho1
- Rho family GTPase Rho4
- Rho family GTPase Rho5
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0048589 (developmental growth), GO:0048856 (anatomical structure development), GO:0009653 (anatomical structure morphogenesis), GO:0016049 (cell growth), GO:0007163 (establishment or maintenance of cell polarity), GO:0045927 (positive regulation of growth), GO:0048584 (positive regulation of response to stimulus), GO:0040008 (regulation of growth), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0000902 (cell morphogenesis), GO:0009967 (positive regulation of signal transduction), GO:0090033 (positive regulation of filamentous growth), GO:0060560 (developmental growth involved in morphogenesis), GO:0009826 (unidimensional cell growth), GO:0010570 (regulation of filamentous growth), GO:1900430 (positive regulation of filamentous growth of a population of unicellular organisms), GO:1900428 (regulation of filamentous growth of a population of unicellular organisms)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0005773 (vacuole), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)