Protein: Rad, Gem/Kir family member 3, isoform E (A0A076NAB7)
Organism: Drosophila melanogaster (Fruit fly)
Sequence: MVDDISPMHHRMQKKTRSASICATGASIETVIHGMPGASGSATPEGGTPGYRRRRPATRSQSARITSGARSVRQKTKAQQQQQQQQHTLQETRSYCTSEPRLSETETPPQRRKLSQRRPQTHAHRKSNAFLDVPTMNMHHLRVNDDDEDVDRLRTFSASKGGIINRGDSFRRRRSRSNSLAPSSPMHTRNGVGGLGGVAGGGSSLGLGCGYNGGSSSNGFGNANAQENHQPVEFYRVEMLGSAGVGKQALLSQFRTSDCINAYDGPECDDAEQNVSIILNGTESELKFLTGNPESKDELEQADAFLVVYSCIDKESFTRAKQILSRLQDMDLLRHRPTILVANKIDLARSRAVSAQDGKCVACTFGAKFIEVSVGINHNCDELLAGTLTQIRLKKDQVQLQLNPKKSKDKDKNKFKENTNIETVETDNCLTDLKADDGGPRDANSPAHWYKSRSVMLASMKARQMLTWILGKEDSKFKHCENLQVL
InterPro domains: - IPR001806: Small GTPase (family) [225-456]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [234-411]
- IPR051641: RGK GTP-binding regulators (family) [21-486]
Interaction partners: - RE33762p
- alkaline phosphatase
- non-specific serine/threonine protein kinase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030234 (enzyme regulator activity), GO:0005515 (protein binding), GO:0140678 (molecular function inhibitor activity), GO:0019899 (enzyme binding), GO:0004857 (enzyme inhibitor activity), GO:0019208 (phosphatase regulator activity), GO:0019902 (phosphatase binding), GO:0019888 (protein phosphatase regulator activity), GO:0019212 (phosphatase inhibitor activity), GO:0004864 (protein phosphatase inhibitor activity), GO:0019903 (protein phosphatase binding), GO:0008157 (protein phosphatase 1 binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0051051 (negative regulation of transport), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0065009 (regulation of molecular function), GO:0048523 (negative regulation of cellular process), GO:0051049 (regulation of transport), GO:0032410 (negative regulation of transporter activity), GO:0032409 (regulation of transporter activity), GO:0044092 (negative regulation of molecular function), GO:0043271 (negative regulation of monoatomic ion transport), GO:0034762 (regulation of transmembrane transport), GO:0034763 (negative regulation of transmembrane transport), GO:0032413 (negative regulation of ion transmembrane transporter activity), GO:0034766 (negative regulation of monoatomic ion transmembrane transport), GO:0034765 (regulation of monoatomic ion transmembrane transport), GO:0051926 (negative regulation of calcium ion transport), GO:0022898 (regulation of transmembrane transporter activity), GO:0043269 (regulation of monoatomic ion transport), GO:1901020 (negative regulation of calcium ion transmembrane transporter activity), GO:2001258 (negative regulation of cation channel activity), GO:1903170 (negative regulation of calcium ion transmembrane transport), GO:1904062 (regulation of monoatomic cation transmembrane transport), GO:0032412 (regulation of monoatomic ion transmembrane transporter activity), GO:1904063 (negative regulation of cation transmembrane transport), GO:0010959 (regulation of metal ion transport), GO:0051924 (regulation of calcium ion transport), GO:1901386 (negative regulation of voltage-gated calcium channel activity), GO:2001257 (regulation of cation channel activity), GO:1901019 (regulation of calcium ion transmembrane transporter activity), GO:1903169 (regulation of calcium ion transmembrane transport), GO:1901385 (regulation of voltage-gated calcium channel activity)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0043229 (intracellular organelle), GO:0005938 (cell cortex), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)