wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Accessory gland-specific peptide 70A (Paragonial peptide B) (Sex peptide) (SP) (P05623)
Organism: Drosophila melanogaster (Fruit fly)
Function: Male seminal protein which triggers short- and long-term post-mating behavioral responses (PMR) in female Drosophila. Binds initially to sperm where it is later cleaved to release an active peptide within the female reproductive tract. Signals via the sex peptide receptor (SPR) in female flies; may also act via other receptors. Moderates the activity of distinct neuronal circuitries in the female genital tract to promote specific PMRs including: enhanced ovulation, increased egg laying rate, increased feeding/foraging rate, induced antimicrobial peptide synthesis, reduced mating receptivity, reduced day-time sleep and reduced lifespan in multiple mated females.
Subcellular location: Secreted {ECO:0000269|PubMed:3135120}.
Sequence: MKTLALFLVLVCVLGLVQSWEWPWNRKPTKFPIPSPNPRDKWCRLNLGPAWGGRC
InterPro domains: - IPR012608: Sex peptide (family) [1-55]
Interaction partners: - Sex peptide receptor
- Accessory gland-specific peptide 26Aa
- Accessory gland protein Acp62F
- Accessory gland protein Acp36DE
- Accessory gland protein Acp29AB
- ACP53C14A
- ACP53C14B
- Accessory gland protein Acp53Ea
- Accessory gland protein Acp63F
- Accessory gland protein Acp76A
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0001664 (G protein-coupled receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009617 (response to bacterium), GO:0043207 (response to external biotic stimulus), GO:0098542 (defense response to other organism), GO:0042742 (defense response to bacterium), GO:0050830 (defense response to Gram-positive bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Fatty acyl-CoA reductase (EC 1.2.1.84) (O46038)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MHHPLSGEMEEFFEDSEIFVTGGSGVVGKALVEKLLRSCNVRRIYVLLRPRKQLTAEQRLVRLRQATVFHVLAVQKPEELDKIVAVPGDVSLPGLGIDPSMMQRMKGVSLVYHCAATVRFDEPLREAVRLNVGGTLEALKFAETLPQLRAFIHVSTFYSNPYLTRVEPKEYTWLSTCVLPGCTLYNAISFGYLMAPCPRLIMGFPNTYTFTKNLAESLVNDYRHRLPVIVYRPSIVLFAVEDPSPGFSPSLMGAMGLFALVGAGILKTVYLGKDIRLDITPQDIGIKSMLCYTKMGYDIYRRGPPADLPVFLSSSCTHVPHTFTQIAEQMDTLDLWRDVAFEKNLMIPGCHYTDKRWAYQFLVFTKQILPALILDLLLRIFGQKPVLMSAVRKAYQTLEVMQPFMFNNWDSPGVSDMETLSKHGEGSAFNFDAFNHPDIHGLVIQSCSNMLHSIRTHLLREDPKTLERSKRILRM
InterPro domains: - IPR013120: Fatty acyl-CoA reductase-like, NAD-binding domain (domain) [20-288]
- IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [9-254]
- IPR026055: Fatty acyl-CoA reductase (family) [9-433]
- IPR033640: Fatty acyl-CoA reductase, C-terminal (domain) [367-432]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016903 (oxidoreductase activity, acting on the aldehyde or oxo group of donors), GO:0016620 (oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:1905954 (positive regulation of lipid localization), GO:0045926 (negative regulation of growth), GO:0048523 (negative regulation of cellular process), GO:0032879 (regulation of localization), GO:0040008 (regulation of growth), GO:0050794 (regulation of cellular process), GO:0010883 (regulation of lipid storage), GO:0010884 (positive regulation of lipid storage), GO:0051128 (regulation of cellular component organization), GO:1905952 (regulation of lipid localization), GO:0001558 (regulation of cell growth), GO:0030308 (negative regulation of cell growth)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0042579 (microbody), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005777 (peroxisome)
Protein: Probable WRKY transcription factor 43 (WRKY DNA-binding protein 43) (Q8GY11)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Sequence: MNGLVDSSRDKKMKNPRFSFRTKSDADILDDGYRWRKYGQKSVKNSLYPRSYYRCTQHMCNVKKQVQRLSKETSIVETTYEGIHNHPCEELMQTLTPLLHQLQFLSKFT
InterPro domains: - IPR044810: WRKY transcription factor, plant (family) [10-89]
- IPR003657: WRKY domain (domain) [24-89]
- IPR036576: WRKY domain superfamily (homologous_superfamily) [14-88]
Interaction partners: - RING/FYVE/PHD zinc finger superfamily protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0009605 (response to external stimulus), GO:0042221 (response to chemical), GO:0009607 (response to biotic stimulus), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0051707 (response to other organism), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0009863 (salicylic acid mediated signaling pathway), GO:0043207 (response to external biotic stimulus), GO:0070887 (cellular response to chemical stimulus), GO:0009617 (response to bacterium), GO:0006952 (defense response), GO:1901700 (response to oxygen-containing compound), GO:0010033 (response to organic substance), GO:0098542 (defense response to other organism), GO:0071310 (cellular response to organic substance), GO:0042742 (defense response to bacterium), GO:0009751 (response to salicylic acid), GO:0014070 (response to organic cyclic compound), GO:1901701 (cellular response to oxygen-containing compound), GO:0071446 (cellular response to salicylic acid stimulus), GO:0071407 (cellular response to organic cyclic compound)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: trypsin (EC 3.4.21.4) (D3GE88)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Secreted, extracellular space {ECO:0000256|ARBA:ARBA00004239}.
Sequence: MKCILGGFLLTCVLCWTEAIIGEMDERWKSSSTSVNGKCILDRDESKYTGKVSVTVSGRICAPWNSIQGSRYSAFKNCYHNYCRNPDDWTQPWCVVKKRNRYVREYCNIPQEAIKPVKRPPTPEPIKQDTELTCGERRLDRQTKIIGGLRSTVESQPWMAAIFKGDGFICGGTLITPCWVLTAAHCFPTGKRTQINRYSVVLGKNAINETDPVKEQKFTVSRLVIHEDFDYSTENYTHDIALLKIEDCNGQCAVKTKTVRTACLPPFQQMLPVGFYCEIAGYGRYQKGTFKFSRYLKQTEVKLISQKVCQRTYYNKDEVNENMLCANGRDWKTDACQGDSGGPLVCEVNNIMFLFGIISWGKECAEKNQPGVYTQVSNYNQWISQHTGLPRYTAGSRYPQKD
InterPro domains: - IPR001314: Peptidase S1A, chymotrypsin family (family) [171-345]
- IPR043504: Peptidase S1, PA clan, chymotrypsin-like fold (homologous_superfamily) [138-388]
- IPR000001: Kringle (domain) [37-113]
- IPR013806: Kringle-like fold (homologous_superfamily) [36-113]
- IPR018056: Kringle, conserved site (conserved_site) [82-94]
- IPR018114: Serine proteases, trypsin family, histidine active site (active_site) [181-186]
- IPR038178: Kringle superfamily (homologous_superfamily) [13-116]
- IPR033116: Serine proteases, trypsin family, serine active site (active_site) [334-345]
- IPR050127: Serine Proteases (Peptidase S1 Family) (family) [35-387]
- IPR009003: Peptidase S1, PA clan (homologous_superfamily) [126-388]
- IPR001254: Serine proteases, trypsin domain (domain) [144-388]
Interaction partners: - Solute carrier family 43 member 3b
- Transmembrane protein 104
- Tumor necrosis factor, alpha-induced protein 8-like protein 2 B
- Regulator of G-protein signaling 18
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0017171 (serine hydrolase activity), GO:0008233 (peptidase activity), GO:0008236 (serine-type peptidase activity), GO:0004175 (endopeptidase activity), GO:0004252 (serine-type endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0009607 (response to biotic stimulus), GO:0051707 (response to other organism), GO:0009617 (response to bacterium), GO:0043207 (response to external biotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Protein FAM163B (P0C2L3)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Sequence: MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKDESEEDEEEPDFAVHSHLPPLHSNRNLVLTNGPALYPTASTSFSQKSPQARALCRSCSHCEPPTFFLQEPPEEEEDVLNGGERVLYKSVSQEDVELPPGGFGGLQALNPNRLSAMREAFARSRSISTDV
InterPro domains: - IPR029379: FAM163 (family) [1-166]
- IPR040280: Protein FAM163B (family) [1-166]
Interaction partners: - Zinc finger C2HC domain-containing protein 1B
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0009987 (cellular process), GO:0051179 (localization), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0051641 (cellular localization), GO:0023051 (regulation of signaling), GO:0023057 (negative regulation of signaling), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0033036 (macromolecule localization), GO:0050794 (regulation of cellular process), GO:0070727 (cellular macromolecule localization), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0010646 (regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:1902532 (negative regulation of intracellular signal transduction), GO:0008104 (protein localization), GO:1902531 (regulation of intracellular signal transduction), GO:0035331 (negative regulation of hippo signaling), GO:0035330 (regulation of hippo signaling)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0005886 (plasma membrane), GO:0005911 (cell-cell junction)
Protein: Rubisco accumulation factor 1.1, chloroplastic (Q9LKR8)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Required for assembly or stability of RuBisCO. Acts at a postchaperonin step to fold and/or assemble the large subunit (rbcL) into RuBisCO. RAF1 binds first to a rbcL dimer (rbcL(2)), leading to a rbcL(8)-RAF1(4) complex formation. In the next step, RBCS displaces RAF1, thus resulting in holoenzyme formation.
Subcellular location: Plastid, chloroplast {ECO:0000305}.
Sequence: MLSLTATTLSSSIFTQSKTHGFFNTRPVYRKPFTTITSALIPASNRQAPPKQQLYQPFRPPPSPIPPKFRSLDTAGKIEVLADRLGLWFEYAPLISSLYTEGFTPPSIEELTGISGVEQNSLIVGAQVRDSLVQSGAKPELIAAFDTNGAELLYEIRLLNTTQRVAAAEYIVDHGFDTKGAGDLARAIKDFPHRRGDVGLGDFDYNLPGDCLSFMLYRKSREHRSPSEIRTTLLEQALETAVTEKAKKAVLRELHGESEEERVKEEEIKIIRVPVVRLRFGEVAGASSVVVLPVCKAEEGEEKLLEAPMEFESGGEFGVVEAEKDWSRWVVLPGWDPVVAVRKGVAVSFSDDREVLPWNGKGEAIMVVIDREKKTVEADNGYYYLVVADGGMKLDRGLVLKEKGVNESLGMVVLVVRPPRDDDDEWQINDEDWD
InterPro domains: - IPR041358: Rubisco accumulation factor 1, alpha-helical domain (domain) [145-254]
- IPR037494: Rubisco accumulation factor 1 (family) [2-434]
- IPR040781: Rubisco accumulation factor 1, helix turn helix domain (domain) [73-133]
- IPR040858: Rubisco accumulation factor 1, C-terminal (domain) [273-420]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0009657 (plastid organization), GO:0009658 (chloroplast organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Nitrogen regulatory protein P-II (PII signal transducing protein) (P0A3F4)
Organism: Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805) (Anacystis nidulans R2)
Function: P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is phosphorylated, these events are reversed. In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is phosphorylated which allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme.
Sequence: MKKIEAIIRPFKLDEVKIALVNAGIVGMTVSEVRGFGRQKGQTERYRGSEYTVEFLQKLKLEIVVEDAQVDTVIDKIVAAARTGEIGDGKIFVSPVDQTIRIRTGEKNADAI
InterPro domains: - IPR002332: Nitrogen regulatory protein P-II, urydylation site (ptm) [46-51]
- IPR015867: Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal (homologous_superfamily) [1-112]
- IPR017918: Nitrogen regulatory protein PII, conserved site (conserved_site) [83-96]
- IPR011322: Nitrogen regulatory PII-like, alpha/beta (homologous_superfamily) [1-112]
- IPR002187: Nitrogen regulatory protein PII (family) [1-112]
Interaction partners: - PipX
- Acetylglutamate kinase
- Ammonium transporter
- Ammonium transporter
- Global nitrogen regulator
- ADP-ribosylglycohydrolase-like
- Glutamine synthetase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048583 (regulation of response to stimulus), GO:0065009 (regulation of molecular function), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0032101 (regulation of response to external stimulus), GO:0050790 (regulation of catalytic activity), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0062012 (regulation of small molecule metabolic process), GO:0046890 (regulation of lipid biosynthetic process), GO:0010565 (regulation of cellular ketone metabolic process), GO:0019216 (regulation of lipid metabolic process), GO:0032104 (regulation of response to extracellular stimulus), GO:0031326 (regulation of cellular biosynthetic process), GO:0042304 (regulation of fatty acid biosynthetic process), GO:0032107 (regulation of response to nutrient levels), GO:0019217 (regulation of fatty acid metabolic process), GO:0006808 (regulation of nitrogen utilization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031469 (bacterial microcompartment), GO:0031470 (carboxysome)
Protein: 2-amino-4-ketopentanoate thiolase beta subunit (EC 2.3.1.263) (AKP thiolase) (AKPT) (C1FW07)
Organism: Unknown prokaryotic organism
Function: Involved in the ornithine fermentation pathway. Catalyzes the thiolytic cleavage of 2-amino-4-ketopentanoate (AKP) with coenzyme A (CoA) to form acetyl-CoA and alanine. It is strictly specific for AKP.
Sequence: MAKDTSYDAVMDRRAEIMSRALGLNYDEFIISDIAFDYEGMMAKAGYSLEEVRQIQSESGVGNTPLLELRNITDLARKTSKRGFGARILIKDEAANPSGSFKDRRASVSIHHAKKLGYPGVLAATSGNYGAAVASQAAMKNLGCIIVQEVFDSRHVGQPEIIEKSRKCEAYGAEVVQLTVGPELFYVSLILLEETGYFNASLYSPFGISGVETLGYELVEQIRARYDKDPAYIVVTHAGGGNVTGTARGALKAGAKNSTIIGASVDLSGLHMASDNDFNKKSFTTGHTGFGVPFATWPDRTDVPKNAARPLRYLDRYVTVTQGEVFYVTEALAQVEGMERGPAGNTSLAAAIALARELPEDEIVVVQETEYTGAGKHPWAQLDFAKQNGIAVKRGAPKENKPGKTIVIPQNFSQITATEMDLNRMRRSYIRNALERNKVKNVTEEDIRFLAEDTKTDADFVTSVIRDLGVRL
InterPro domains: - IPR001926: Tryptophan synthase beta chain-like, PALP domain (domain) [60-366]
- IPR050214: Cysteine synthase/Cystathionine beta-synthase (family) [60-366]
- IPR053471: 2-amino-4-ketopentanoate thiolase beta subunit (family) [6-467]
- IPR036052: Tryptophan synthase beta chain-like, PALP domain superfamily (homologous_superfamily) [23-367]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0005515 (protein binding), GO:0016829 (lyase activity), GO:0019842 (vitamin binding), GO:0046983 (protein dimerization activity), GO:0043168 (anion binding), GO:0042802 (identical protein binding), GO:0016835 (carbon-oxygen lyase activity), GO:0070279 (vitamin B6 binding), GO:0042803 (protein homodimerization activity), GO:0030170 (pyridoxal phosphate binding), GO:0016836 (hydro-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0006520 (amino acid metabolic process), GO:0006082 (organic acid metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0043436 (oxoacid metabolic process), GO:1901605 (alpha-amino acid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0006591 (ornithine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0033643 (host cell part), GO:0043657 (host cell), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0033647 (host intracellular organelle), GO:0030430 (host cell cytoplasm), GO:0033648 (host intracellular membrane-bounded organelle), GO:0042025 (host cell nucleus)
Protein: Gonadotropin releasing hormone receptor 4 isoform X1 (Gonadotropin-releasing hormone receptor 4) (Gonadotropin-releasing hormone receptor GnRH-R4SHS) (A3QJZ0)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
Sequence: MNDSSPTSENIMFHQLTADTLNGSCDLPTCNNNTGEAALQLPTFSMAAKVRVIITFTLCAVSAVCNLGVLWAASTNNKRKSHVRILIMNLTVADLLVTFIVMPVDAAWNITVQWLAGDLACRLLMFLKLVAMYSCAFVTVVISLDRQSAILNPLAINKAKKKNKIMLSVAWAMSVVLSVPQMFLFHNVTITVPANFTQCTTRGSFVKHWQETIYNMFTFICLFLIPLAIMICCYTRILVEISRRMTKGNISSKEVHLRRSHSNIPKARMRTLKMSIVIVTSFIVCWTPYYLLGLWYWFLPEDLEETVSHSLTHMLFIFGLFNAILDPITYGLFTIHFRKGLKRYCRSAVVLTESENNSIITGSLKCSPSPFRMKRVTQSGTGTDPKQNTSTVGEEDKKAADGKTKE
InterPro domains: - IPR001658: Gonadotrophin-releasing hormone receptor family (family) [47-315]
- IPR017452: GPCR, rhodopsin-like, 7TM (domain) [65-330]
- IPR000276: G protein-coupled receptor, rhodopsin-like (family) [66-338]
Interaction partners: - Progonadoliberin
- Progonadoliberin
- Guanine nucleotide-binding protein subunit alpha
- Guanine nucleotide-binding protein subunit alpha
- Follicle-stimulating hormone beta subunit
- Gonadotropin-releasing hormone receptor 1
- Gonadotropin-releasing hormone receptor 2.
- Lhb protein
- KiSS-1 metastasis suppressor
- Prokineticin
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0016500 (protein-hormone receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004930 (G protein-coupled receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007186 (G protein-coupled receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)