Protein: Cbb3-type cytochrome c oxidase subunit CcoN1 (EC 7.1.1.9) (Cytochrome CBB3 subunit CcoN1) (D9IA43)
Organism: Stutzerimonas stutzeri (Pseudomonas stutzeri)
Function: Cbb3-type cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits CcoN and CcoO form the functional core of the enzyme complex. Subunits CcoP and CcoQ may optionally bind to the core. CcoN is the catalytic subunit of the enzyme. Electrons originating in cytochrome c or a quinol are transferred to the bimetallic center formed by a high-spin heme and copper B. The complex also functions as a proton pump.
Subcellular location: Cell inner membrane {ECO:0000250|UniProtKB:P0ABI8}; Multi-pass membrane protein {ECO:0000255}.
Sequence: MNTATSTAYSYKVVRQFAIMTVVWGIVGMGLGVFIAAQLAWPFLNFDLPWTSFGRLRPLHTNAVIFAFGGCALFATSYYSVQRTCQTTLFAPKLAAFTFWGWQLVILLAAISLPLGFTSSKEYAELEWPIDILITIVWVAYAVVFFGTLAKRKVKHIYVGNWFFGAFILTVAILHVVNNLEIPVTAMKSYSLYAGATDAMVQWWYGHNAVGFFLTAGFLGIMYYFVPKQAERPVYSYRLSIVHFWALITVYIWAGPHHLHYTALPDWAQSLGMVMSLILLAPSWGGMINGMMTLSGAWHKLRSDPILRFLVVSLAFYGMSTFEGPMMAIKTVNALSHYTDWTIGHVHAGALGWVAMVSIGALYHLVPKVFGREQMHSIGLINTHFWLATIGTVLYIASMWVNGIAQGLMWRAINDDGTLTYSFVESLEASHPGFVVRMIGGAIFFAGMLVMAYNTWRTVQAAKPAEYDAAAQIA
InterPro domains: - IPR000883: Cytochrome c oxidase subunit I (family) [9-463]
- IPR036927: Cytochrome c oxidase-like, subunit I superfamily (homologous_superfamily) [2-471]
- IPR004677: Cytochrome c oxidase cbb3-type, subunit I (family) [8-471]
- IPR023615: Cytochrome c oxidase, subunit I, copper-binding site (binding_site) [203-258]
- IPR023616: Cytochrome c oxidase-like, subunit I domain (domain) [1-474]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016661 (oxidoreductase activity, acting on other nitrogenous compounds as donors), GO:0016662 (oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006091 (generation of precursor metabolites and energy), GO:0015980 (energy derivation by oxidation of organic compounds), GO:0022900 (electron transport chain), GO:0022904 (respiratory electron transport chain), GO:0045333 (cellular respiration), GO:0019646 (aerobic electron transport chain), GO:0009060 (aerobic respiration), GO:0042773 (ATP synthesis coupled electron transport), GO:0006123 (mitochondrial electron transport, cytochrome c to oxygen), GO:0042775 (mitochondrial ATP synthesis coupled electron transport), GO:0006119 (oxidative phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0070069 (cytochrome complex), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)