Protein: Alcohol dehydrogenase (EC 1.1.1.1) (P00332)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000250|UniProtKB:P00330}.
Sequence: MTIPDKQLAAVFHTHGGPENVKFEEVPVAEPGQDEVLVNIKYTGVCHTDLHALQGDWPLPAKMPLIGGHEGAGVVVKVGAGVTRLKIGDRVGVKWMNSSCGNCEYCMKAEETICPHIQLSGYTVDGTFQHYCIANATHATIIPESVPLEVAAPIMCAGITCYRALKESKVGPGEWICIPGAGGGLGHLAVQYAKAMAMRVVAIDTGDDKAELVKSFGAEVFLDFKKEADMIEAVKAATNGGAHGTLVLSTSPKSYEQAAGFARPGSTMVTVSMPAGAKLGADIFWLTVKMLKICGSHVGNRIDSIEALEYVSRGLVKPYYKVQPFSTLPDVYRLMHENKIAGRIVLDLSK
InterPro domains: - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [146-316]
- IPR020843: Enoylreductase domain (domain) [16-346]
- IPR013149: Alcohol dehydrogenase-like, C-terminal (domain) [184-310]
- IPR011032: GroES-like superfamily (homologous_superfamily) [9-178]
- IPR013154: Alcohol dehydrogenase-like, N-terminal (domain) [32-143]
- IPR002328: Alcohol dehydrogenase, zinc-type, conserved site (conserved_site) [68-82]
Interaction partners: - Alcohol dehydrogenase 4
- Probable pyruvate decarboxylase Pdc101
- Probable pyruvate decarboxylase C186.09
- Putative aldehyde dehydrogenase-like protein C9E9.09c
- Putative aldehyde dehydrogenase-like protein C922.07c
- Putative pyruvate decarboxylase C13A11.06
- Putative pyruvate decarboxylase C3G9.11c
- Putative S-
- Probable S-
- Uncharacterized oxidoreductase C26F1.07
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor), GO:0018455 (alcohol dehydrogenase [NAD(P)+] activity), GO:0004022 (alcohol dehydrogenase (NAD+) activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0098754 (detoxification), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0071704 (organic substance metabolic process), GO:1990748 (cellular detoxification), GO:0044281 (small molecule metabolic process), GO:0009056 (catabolic process), GO:1901700 (response to oxygen-containing compound), GO:0044282 (small molecule catabolic process), GO:1901575 (organic substance catabolic process), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0006081 (cellular aldehyde metabolic process), GO:0044248 (cellular catabolic process), GO:0009636 (response to toxic substance), GO:0110095 (cellular detoxification of aldehyde), GO:0097237 (cellular response to toxic substance), GO:0046185 (aldehyde catabolic process), GO:1901701 (cellular response to oxygen-containing compound), GO:0110096 (cellular response to aldehyde)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)