Protein: Nephrin (Q1KMS5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Sequence: MDSWLSLVFSSGCFLLLVDFKGVCGQQAFKTEPRNVTVRAGATALLKCEVLRASGAVQWVKDGLLLRPLRSLPGYPRYSMTGDQKKGQYHLQILDVTLEDDGPYECQVGRSESSRPIVSRTVWLNVQIPSSQPYFQLESEEPWVEGEQYTVTCIAPDAKPPAEITIFRDGEELLESESYTMSGSQDKLQNTHAEVTIRARSSDDTRRLTCRAKNPASPRALETGMTMKVYFPPQAPMIMGLENEEVKAGSFLKVVCMSYGGNPLATLHWTKNGEVLSTSWDVDFVSRRASSVLKMEVKPEDNHAVLQCQSINQVTRSPMSLTRTLTVPFEPAEVTLLGSFEAVEGEEINLSCSTSSSNPPVHIRWWLGFKELNRTEVTFAEGDNGGMMTVSNLTHKVSREDNGLSLQCEAFNKGTRFSSVRAAELIVYYPPQKVWLDAPPPNVFLHSGSTLRLVCFSSGGNPTGQLTWLKNNKVVLTASKQVSSERGVSRELLLTLHPSDNLATYRCDSSNKAKKVLSAQTKFRVLFPAVSVKIVAKQKELRRGQTLDLDCLAGSSNPTANISWSLGPVILKGVDQAPKRAEFGGMSRTSKLSLTLEPHHWRKRITCQAFSNVLSEGVNNFYSLDVLFPPEFSAEQPDEVQVIEDETATLPAKVSANPDEITCEWIFQGEKLVKERDPRYTFSDWTLEIVNVSRRDGGDYIIECSNAEGSNRTKLRLDVQYSPTVRMKSDPVFVNIGDTADLLCVADANPITSSMFSWKWMGEGERDELGEESEDDGTGVLTIYEVTRDRAGVYQCTADNGISPTGSVEGQLIVRFAPDLQKGPQWRKVASRGDGSNDANVVCQAQGVPRVQFRWAKNGFPLDLGNPRYEETTESTGTIHTSILTVINVSAALDYAIFTCTAHNSMGEDSLDIQLLSTNHPDPPSDLKLLRVDQTSVTLEWMPGFDGGLTQIFRVRYQWAGSASYMYVDVFPPTATVYTVTGLNPSTMYNFSVNALNSIGESSYADNNKILTVTTADAKEADGGVSTADQDSALAGGGLPVYVVVILVVGGVLFLLNPFICFLLARWKRRRSLKGNTSSISQETKSEEQRSTASSSTRYASRELINASAQRTLLVDSSSEPDSSVYESYGRQENPHYYYPTEAYSPALYAHPEGPEDCDGRHGTSPFTHVYEEVRGMYEDLQACSPLPPAAHIHPQAPFSTYYEGRAYSKADVDVTIGAYDSMVYRRRRDTDLPFELRGELV
InterPro domains: - IPR036116: Fibronectin type III superfamily (homologous_superfamily) [907-1012]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [23-924]
- IPR003961: Fibronectin type III (domain) [921-1018]
- IPR013098: Immunoglobulin I-set (domain) [28-915]
- IPR013162: CD80-like, immunoglobulin C2-set (domain) [139-612]
- IPR007110: Immunoglobulin-like domain (domain) [27-914]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [24-1021]
- IPR003598: Immunoglobulin subtype 2 (domain) [39-907]
- IPR003599: Immunoglobulin domain subtype (domain) [33-918]
- IPR051275: Cellular adhesion and signaling domain-containing protein (family) [15-335]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0035295 (tube development), GO:0009790 (embryo development), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0048839 (inner ear development), GO:0048513 (animal organ development), GO:0035239 (tube morphogenesis), GO:0090596 (sensory organ morphogenesis), GO:0048568 (embryonic organ development), GO:0042472 (inner ear morphogenesis), GO:0060872 (semicircular canal development), GO:0048562 (embryonic organ morphogenesis), GO:0048752 (semicircular canal morphogenesis), GO:0007423 (sensory organ development), GO:0042471 (ear morphogenesis), GO:0043583 (ear development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0005886 (plasma membrane), GO:0005911 (cell-cell junction)