Protein: protein-lysine 6-oxidase (EC 1.4.3.13) (Q5FWS5)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Secreted, extracellular space {ECO:0000256|ARBA:ARBA00004239}.
Sequence: MALAGAGSQLGTLVWGACLCVLVHGQQEQPGQGSDPGRWRQLIQWENNGQVYSLLNSGSEYVPAGPQRGESSSRVLLAGAPQTSQRRSQGGPRRRQAPNLPLPGRVGSDTVRGQTRHPFGFGQVPDNWREVAVGDSNGMARARTSVSQQRHGGSASSSVSASAFATTYRQPSSYPQQFPYPQAPFVNQYENYDPASRTYEQGYVYYRGAGGGMGAGAAAAAVASAGVIYPFQPRARYEEYGGGGEEQPEYPAQGFYPAPERPYAPQPQPQPQPQPQPQPQPSDGLDRRYSHSLYNEGTPGFEQAYPDPSTDVSQIPAGAGGTYGAAGDPRLGWYPPYAANVPPEAYVPPRAVEPQPPFRVLEPPYLPVRNSDAPSQGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDLRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDASTGKKVAEGHKASFCLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRFVSTTNCKIVQS
InterPro domains: - IPR050912: Lysyl oxidase-like protein (family) [402-605]
- IPR001695: Lysyl oxidase (family) [391-608]
- IPR019828: Lysyl oxidase, conserved site (conserved_site) [477-490]
Interaction partners: - Fibulin-5
- Fibrillin-1
- NYN domain and retroviral integrase containing
- Latent-transforming growth factor beta-binding protein 2
- Metalloendopeptidase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0043167 (ion binding), GO:0140096 (catalytic activity, acting on a protein), GO:0016491 (oxidoreductase activity), GO:0043169 (cation binding), GO:0016638 (oxidoreductase activity, acting on the CH-NH2 group of donors), GO:0016641 (oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor), GO:0046872 (metal ion binding), GO:0046914 (transition metal ion binding), GO:0005507 (copper ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0009605 (response to external stimulus), GO:0048870 (cell motility), GO:0044237 (cellular metabolic process), GO:0007155 (cell adhesion), GO:0009719 (response to endogenous stimulus), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0009611 (response to wounding), GO:0019538 (protein metabolic process), GO:0007166 (cell surface receptor signaling pathway), GO:0016043 (cellular component organization), GO:0043170 (macromolecule metabolic process), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0016477 (cell migration), GO:0036211 (protein modification process), GO:0042060 (wound healing), GO:0043412 (macromolecule modification), GO:0007167 (enzyme-linked receptor protein signaling pathway), GO:0043062 (extracellular structure organization), GO:0033993 (response to lipid), GO:0048545 (response to steroid hormone), GO:0014070 (response to organic cyclic compound), GO:0045229 (external encapsulating structure organization), GO:0097435 (supramolecular fiber organization), GO:0022607 (cellular component assembly), GO:0030198 (extracellular matrix organization), GO:0007169 (transmembrane receptor protein tyrosine kinase signaling pathway), GO:0030199 (collagen fibril organization), GO:0085029 (extracellular matrix assembly), GO:1900120 (regulation of receptor binding), GO:0048008 (platelet-derived growth factor receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0043229 (intracellular organelle), GO:0031012 (extracellular matrix), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)