wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Eukaryotic aspartyl protease family protein (Q9C8C9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MSPIPKPLFFFFFLNYVSLSTSLSLHLPLTSLPISTTTNSHRFTTSLLSRKNPSPSSPPYNFRSRFKYSMALIISLPIGTPPQAQQMVLDTGSQLSWIQCHRKKLPPKPKTSFDPSLSSSFSTLPCSHPLCKPRIPDFTLPTSCDSNRLCHYSYFYADGTFAEGNLVKEKITFSNTEITPPLILGCATESSDDRGILGMNRGRLSFVSQAKISKFSYCIPPKSNRPGFTPTGSFYLGDNPNSHGFKYVSLLTFPESQRMPNLDPLAYTVPMIGIRFGLKKLNISGSVFRPDAGGSGQTMVDSGSEFTHLVDAAYDKVRAEIMTRVGRRLKKGYVYGGTADMCFDGNVAMIPRLIGDLVFVFTRGVEILVPKERVLVNVGGGIHCVGIGRSSMLGAASNIIGNVHQQNLWVEFDVTNRRVGFAKADCSRVV
InterPro domains: - IPR033121: Peptidase family A1 domain (domain) [72-422]
- IPR001461: Aspartic peptidase A1 (family) [78-413]
- IPR051708: Plant Aspartic Proteinase A1 (family) [9-427]
- IPR021109: Aspartic peptidase domain superfamily (homologous_superfamily) [49-430]
- IPR032861: Xylanase inhibitor, N-terminal (domain) [73-228]
- IPR034161: Pepsin-like domain, plant (domain) [73-426]
- IPR032799: Xylanase inhibitor, C-terminal (domain) [266-423]
Interaction partners: - Protein DUF642 L-GALACTONO-1,4-LACTONE-RESPONSIVE GENE 1
- E3 ubiquitin-protein ligase ATL15
- Leucine-rich repeat
- Protein DETOXIFICATION 25
- At1g73120
- C3HC4-type RING finger protein
- C3HC4-type RING finger protein
- Protein DUF642 L-GALACTONO-1,4-LACTONE-RESPONSIVE GENE 2
- Alpha carbonic anhydrase 1, chloroplastic
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0009627 (systemic acquired resistance)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Small protein MntS (P0DKB3)
Organism: Escherichia coli (strain K12)
Function: Required for repression of mntH by MntR. May function as a chaperone that makes manganese more available by delivering it to the necessary cellular locations when manganese is limiting.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:21778229}. Note=May be loosely associated with the inner membrane.
Sequence: MNEFKRCMRVFSHSPFKVRLMLLSMLCDMVNNKPQQDKPSDK
InterPro domains: - IPR047782: Manganase accumulation protein MntS (family) [1-39]
Interaction partners: - Transcriptional regulator MntR
- Probable manganese efflux pump MntP
- Cytochrome bd-I ubiquinol oxidase subunit X
- Multidrug efflux pump accessory protein AcrZ
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0009292 (horizontal gene transfer), GO:0009294 (DNA-mediated transformation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0009295 (nucleoid), GO:0043229 (intracellular organelle), GO:0043590 (bacterial nucleoid), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle)
Protein: Type-5 uracil-DNA glycosylase (EC 3.2.2.-) (TTUDGB) (Uracil/hypoxanthine/xanthine DNA glycosylase) (Q5SJ65)
Organism: Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
Function: DNA glycosylase with broad substrate specificity. Can remove uracil from double-stranded DNA containing either a U/G, U/A, U/C or U/T base pair. Can also excise hypoxanthine from double-stranded DNA containing G/I, T/I, and A/I base pairs, xanthine from both double-stranded and single stranded DNA, thymine from G/T mismatched DNA, 5'-hydroxymethyluracil and 5'-fluorouracil.
Sequence: MDREAFVQTLTACRLCPRLVAWREEVVGRKRAFRGEPYWARPVPGFGDPEARILLFGLAPGAHGSNRTGRPFTGDASGAFLYPLLHEAGLSSKPESLPGDDLRLYGVYLTAAVRCAPPKNKPTPEELRACARWTEVELGLLPEVRVYVALGRIALEALLAHFGLRKSAHPFRHGAHYPLPGGRHLLASYHVSRQNTQTGRLTREMFLEVLMEAKRLAGL
InterPro domains: - IPR051536: Uracil-DNA glycosylase family, Type-4/5 (family) [4-217]
- IPR044147: Uracil DNA glycosylase family 5 (domain) [13-215]
- IPR005122: Uracil-DNA glycosylase-like (domain) [44-212]
- IPR036895: Uracil-DNA glycosylase-like domain superfamily (homologous_superfamily) [1-219]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016787 (hydrolase activity), GO:0051540 (metal cluster binding), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0140097 (catalytic activity, acting on DNA), GO:0051536 (iron-sulfur cluster binding), GO:0016799 (hydrolase activity, hydrolyzing N-glycosyl compounds), GO:0019104 (DNA N-glycosylase activity), GO:0051539 (4 iron, 4 sulfur cluster binding), GO:0097506 (deaminated base DNA N-glycosylase activity), GO:0004844 (uracil DNA N-glycosylase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0033554 (cellular response to stress), GO:0006259 (DNA metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0006974 (cellular response to DNA damage stimulus), GO:0006281 (DNA repair), GO:0006284 (base-excision repair)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Spermatogenesis-associated protein 20 (Sperm-specific protein 411) (Ssp411) (Transcript increased in spermiogenesis 78 protein) (Q80YT5)
Organism: Mus musculus (Mouse)
Function: May play a role in fertility regulation.
Subcellular location: Secreted {ECO:0000305}.
Sequence: MSHHSSPPPKHKGEHKGHGLPRGSERGSSSRDKDRSATTVSSSAPMPAGGKSSRTNCPPPAPPKTVNRLINEKSPYLLQHAYNPVDWYPWGQEAFDKAKKENKPIFLSVGYSTCHWCHMMEEESFQNEEIGRLLNENFICVMVDREERPDVDKVYMTFVQATSSGGGWPMNVWLTPGLQPFVGGTYFPPEDGLTRVGFRTVLMRICDQWKLNKNTLLENSQRVTTALLARSEISVGDRQIPASAATMNSRCFQQLDEGYDEEYGGFAEAPKFPTPVILNFLFSYWLSHRLTQDGSRAQQMALHTLKMMANGGIQDHVGQGFHRYSTDRQWHIPHFEKMLYDQAQLSVVYTQAFQISGDEFYADVAKGILQYVTRTLSHRSGGFYSAEDADSPPERGMKPQEGAYYVWTVKEVQQLLPEPVVGASEPLTSGQLLMKHYGLSEVGNINSSQDPNGELHGQNVLMVRYSLELTAARYGLEVEAVRALLNTGLEKLFQARKHRPKAHLDNKMLAAWNGLMVSGFAVTGAALGMEKLVAQATSGAKFLKRHMFDVSSGRLKRTCYAGTGGTVEQSNPPCWGFLEDYAFVVRGLLDLYEASQESSWLEWALRLQDTQDKLFWDPRGGGYFCSEAELGADLPLRLKDDQDGAEPSANSVSAHNLLRLHSFTGHKDWMDKCVCLLTAFSERMRRVPVALPEMVRTLSAQQQTLKQIVICGDPQAKDTKALLQCVHSIYVPNKVLILADGDPSSFLSRQLPFLSSLRRVEDRATVYIFENQACSMPITDPCELRKLLHQ
InterPro domains: - IPR012341: Six-hairpin glycosidase-like superfamily (homologous_superfamily) [501-701]
- IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [67-193]
- IPR004879: Spermatogenesis-associated protein 20-like, TRX domain (domain) [67-227]
- IPR024705: Spermatogenesis-associated protein 20 (family) [45-790]
- IPR008928: Six-hairpin glycosidase superfamily (homologous_superfamily) [253-645]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016667 (oxidoreductase activity, acting on a sulfur group of donors), GO:0016670 (oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044255 (cellular lipid metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006629 (lipid metabolic process), GO:1901575 (organic substance catabolic process), GO:0044248 (cellular catabolic process), GO:0019538 (protein metabolic process), GO:0006665 (sphingolipid metabolic process), GO:0044242 (cellular lipid catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0016042 (lipid catabolic process), GO:0030163 (protein catabolic process), GO:0030149 (sphingolipid catabolic process), GO:0046466 (membrane lipid catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Probable cell division protein WhiA (P9WF45)
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function: Involved in cell division and chromosome segregation.
Sequence: MAMTTDVKDELSRLVVKSVSARRAEVTSLLRFAGGLHIVGGRVVVEAELDLGSIARRLRKEIFELYGYTAVVHVLSASGIRKSTRYVLRVANDGEALARQTGLLDMRGRPVRGLPAQVVGGSIDDAEAAWRGAFLAHGSLTEPGRSSALEVSCPGPEAALALVGAARRLGVGAKAREVRGADRVVVRDGEAIGALLTRMGAQDTRLVWEERRLRREVRATANRLANFDDANLRRSARAAVAAAARVERALEILGDTVPEHLASAGKLRVEHRQASLEELGRLADPPMTKDAVAGRIRRLLSMADRKAKVDGIPDTESVVTPDLLEDA
InterPro domains: - IPR003802: Sporulation regulator WhiA (family) [1-310]
- IPR039518: WhiA, LAGLIDADG-like domain (domain) [127-218]
- IPR027434: Homing endonuclease (homologous_superfamily) [1-211]
- IPR023054: Sporulation regulator WhiA, C-terminal (domain) [221-303]
- IPR018478: Sporulation transcription regulator WhiA, N-terminal domain (domain) [20-104]
Interaction partners: - Putative gluconeogenesis factor
- Nucleotide-binding protein Rv1421
- Probable protein-export membrane protein SecG
- Transcriptional regulator WhiB2
- UvrABC system protein C
- Phosphoenolpyruvate transferase
- Possible transcriptional regulatory protein
- dITP/XTP pyrophosphatase
- Cell division protein FtsZ
- Uncharacterized HTH-type transcriptional regulator Rv1828
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050793 (regulation of developmental process), GO:0043937 (regulation of sporulation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Protein SPA1-RELATED 3 (Q9LJR3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Repressor of photomorphogenesis in the light. Probably part of the COP1/SPA E3 ubiquitin-protein ligase complex.
Subcellular location: Nucleus {ECO:0000250}.
Sequence: MEGSSNSNSRGFNTSGVSDRNTEFLPVERLTTRSKPSSHVDEYVRSLFGSTSTHKSGEDDSLGIDPFVRSLEWGDVSLRQWLDKPERSVDVFECLHVFRQIVEIVNAAHSQGIVVHNVRPSCFVMSSFNHVSFIESASCSDSGSDSLEDGPISQKEIGSSRREEAVSKAIAIEEKGVYNKLLERKIEKLEEEKTQPFPMKHILAMETSWYTSPEEDFGSSSTCASDVYRLGVLLFELFCPVPSREEKSRTMSSLRHRVLPPQILLKCPKEASFCLWLLHPEPTCRPSMSDLLQSEFITEPRDNLEEREAAIELRDRIEEQESLLEFLLLIQQRKQESAYRLQDTVSLLSSDIEQVVKRQLILKKRGSSLSDFSKDDHQYTSGQPLMSFQANEEPSAFLASRKRVRQGILALENGVEVDEESQGSTLLESSRLMRNFKKLESVYFLTRRRQMKAAASGKSLTRHSPLSSENGRGSMIVSEKSSVSNPVAPKAFFNNDSRQGGWIDPFLEGLCRYLSFSQLRVKADLKQGDLLNSSNLVCALAFDREGELFATAGVNKKIKIFECNSIVNDNRDIHYPVVELAGRSKLSSLCWNSYIKSQIASSNFDGVVQIWDVARSQLVTEMKEHKKRVWSIDISSADPTLLASGSDDGTVKLWSINQGVSIGTIKTKANVCCVQFPSDSGRSLAFGSADHKVYYYDLRNPKIPLCTMIGHSKTVSYVKFVDSSTLVSSSTDNTLKLWDLSMSASGINESPLHSFTGHTNLKNFVGLSVSDGYIATGSETNEVFVYHKAFPMPVMSYMFNNTDSMSGLEVDDASQFISSICWRGQSSTLVAANSNGNIKILEMMT
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [66-305]
- IPR019775: WD40 repeat, conserved site (conserved_site) [726-740]
- IPR001680: WD40 repeat (repeat) [527-842]
- IPR020472: PAC1/LIS1-like, WD-40 repeat (repeat) [599-740]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [508-845]
- IPR000719: Protein kinase domain (domain) [1-297]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [531-842]
- IPR044630: WD-repeat protein SPA1/2/3/4 (family) [50-844]
Interaction partners: - E3 ubiquitin-protein ligase COP1
- Ubiquitin-ribosomal protein eL40z fusion protein
- Ubiquitin-ribosomal protein eL40y fusion protein
- Phytochrome A
- Ubiquitin-ribosomal protein eS31z fusion protein
- Ubiquitin-ribosomal protein eS31y fusion protein
- Ubiquitin-ribosomal protein eS31x fusion protein
- Protein NBR1 homolog
- E3 ubiquitin-protein ligase PRT1
- Cryptochrome-2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0009314 (response to radiation), GO:0009416 (response to light stimulus), GO:0009637 (response to blue light)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0016604 (nuclear body), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: NifU-like protein 1, chloroplastic (AtCNfu1) (AtCnfU-IVb) (Q93W77)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Molecular scaffold for [Fe-S] cluster assembly of chloroplastic iron-sulfur proteins.
Subcellular location: Plastid, chloroplast stroma {ECO:0000269|PubMed:12553879, ECO:0000269|PubMed:15031412}.
Sequence: MMASLATSISGSFRILVKSSSTRNGFPVISDQNPSFVLFANKRRHISRTAIFHRSAISGSSQGEKISPLASGVSSGLYSAQTFDLTPQNVDLVLEDVRPFLISDGGNVDVVSVEDGVVSLKLQGACTSCPSSSTTMTMGIERVLKEKFGDALKDIRQVFDEEVKQITVEAVNAHLDILRPAIKNYGGSVEVLSVEGEDCVVKYVGPESIGMGIQAAIKEKFKDISNVTFTS
InterPro domains: - IPR001075: NIF system FeS cluster assembly, NifU, C-terminal (domain) [91-150]
- IPR034904: Fe-S cluster assembly domain superfamily (homologous_superfamily) [82-229]
Interaction partners: - Iron-sulfur cluster assembly protein 1
- Cysteine desulfurase, mitochondrial
- Monothiol glutaredoxin-S14, chloroplastic
- Lipoyl synthase, chloroplastic
- Lipoyl synthase, mitochondrial
- Protein BOLA1
- Fe-S cluster assembly factor HCF101, chloroplastic
- Frataxin, mitochondrial
- Dihydroxy-acid dehydratase, chloroplastic
- Iron-sulfur cluster co-chaperone protein HscB homolog
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044237 (cellular metabolic process), GO:0016043 (cellular component organization), GO:0006091 (generation of precursor metabolites and energy), GO:0015979 (photosynthesis), GO:0044085 (cellular component biogenesis), GO:0019684 (photosynthesis, light reaction), GO:0043933 (protein-containing complex organization), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009532 (plastid stroma), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009570 (chloroplast stroma), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Mitochondrial fission 1 protein B (FIS1 homolog B) (AtFIS1b) (Q94CK3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the peroxisomal and mitochondrial division machineries. Plays a role in promoting the fission of mitochondria and peroxisomes. In association with PEX11C, PEX11D, PEX11E and DRP3A, is involved in cell cycle-associated constitutive self-replication of preexisting peroxisomes.
Subcellular location: Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Sequence: MDAAIGKVFDSVSDFFSGAASASADEFPLCDSDIISGCEKELAEAQDEGRKKECIMRLSWALVHSKMPSDIQRGIAMLEALVVNDTSAMKLREKLYLLALGYYRSGDFSRSRDCIERCLEVEPESGQAQALKKAIEDRIVKDGVIGVGIAVTAVGVVAGIAAAILRS
InterPro domains: - IPR028061: Fis1, C-terminal tetratricopeptide repeat (repeat) [92-144]
- IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [22-166]
- IPR016543: Mitochondria fission 1 protein (family) [4-167]
- IPR028058: Fis1, N-terminal tetratricopeptide repeat (repeat) [53-84]
- IPR019734: Tetratricopeptide repeat (repeat) [92-125]
- IPR033745: Mitochondria fission protein Fis1, cytosolic domain (domain) [28-143]
Interaction partners: - Peroxisomal membrane protein 11E
- Peroxisomal membrane protein 11C
- Peroxisomal membrane protein 11D
- Dynamin-related protein 3A
- Dynamin-related protein 3B
- Peroxisomal membrane protein 11B
- Dynamin
- Peroxisome biogenesis protein 16
- Dynamin-like protein ARC5
- Peroxisomal membrane protein PEX14
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0007005 (mitochondrion organization), GO:0007031 (peroxisome organization), GO:0048285 (organelle fission), GO:0016559 (peroxisome fission)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0042579 (microbody), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle), GO:0005777 (peroxisome)
Protein: Interleukin-12 subunit beta (IL-12B) (Cytotoxic lymphocyte maturation factor 40 kDa subunit) (IL-12 subunit p40) (Q62712)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Secreted {ECO:0000256|RuleBase:RU281113}.
Sequence: MCHQKLTFSWFAMVLLVSPLMAMWELEKDVYVVEVDWRPDAPGETVTLTCDSPEEDDITWTSDQRRGVIGSGKTLTITVREFLDAGQYTCHRGGETLSHSHLLLHKKENGIWSTEILKNFKNKTFLKREAPNYSGRFTCSWLVHRNTDLKFNIKSSSSSPESRAVTCGAASLSAEKVTLNQRDYEKYSVACQEDVTCPTAEETLPIELVVEAQQQNKYENYSTSFFIRDIIKPDPPKNLQVKPLKNSQVEVSWEYPDSWSTPHSYFSL
InterPro domains: - IPR036116: Fibronectin type III superfamily (homologous_superfamily) [110-265]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [32-107]
- IPR003961: Fibronectin type III (domain) [233-268]
- IPR019482: Interleukin-12 beta, central domain (domain) [123-213]
- IPR050676: Interleukin-12 (family) [1-268]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [23-268]
- IPR007110: Immunoglobulin-like domain (domain) [43-90]
- IPR003598: Immunoglobulin subtype 2 (domain) [41-97]
- IPR015528: Interleukin-12 beta (family) [126-268]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0019955 (cytokine binding)
Biological Process (BP): GO:0008150 (biological process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0002252 (immune effector process), GO:0001775 (cell activation), GO:0045321 (leukocyte activation), GO:0003008 (system process), GO:0006955 (immune response), GO:0050877 (nervous system process), GO:0002366 (leukocyte activation involved in immune response), GO:0046649 (lymphocyte activation), GO:0002263 (cell activation involved in immune response), GO:0007600 (sensory perception), GO:0002285 (lymphocyte activation involved in immune response), GO:0030101 (natural killer cell activation), GO:0019233 (sensory perception of pain)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005615 (extracellular space), GO:0005576 (extracellular region)