Protein: Acid phosphatase (EC 3.1.3.2) (P08091)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Not known
Subcellular location: Secreted, cell wall.
Sequence: MFLQNLFLGFLAVVCANAQFAEFTAFDGKFDFKEHLTSRSPYHKPYFYGPSIDFPTTCKIKQVHTLQRHGSRNPTGGNAAFDAVGIANFQQRLLNGSVPIDYSVSGNPLSFVPTWTPVIEAANADALSSSGRVELFDMGRQFYERYHELFNASTYNIYTAAQQRVVDSALWYGYGMFGEDVHNFTNYILVSENATAGSNSLSSYNACPASDADDFTTPALEAWRNVYMPPIRQRLNPYFSNYNLTNDDILNLYGICSYEIALQDYSEFCKLFNSVDFLNFEYEGDLSFSYGMGNSVKWGSIFGGAYANSLANSLRSVENNTQQVFFAFTHDANIIPVETALGFFTDNTPENPLPTSYQVHSHSMKASEFVPFAGNLITELFQCEDSKYYVRHLVNEEVFPLSDCGFGPSNTSDGMCELYAYLNSPVRVNGTSNGIQNFDTLCNASAVAAVYPY
InterPro domains: - IPR000560: Histidine phosphatase superfamily, clade-2 (family) [59-395]
- IPR033379: Histidine acid phosphatase active site (active_site) [60-340]
- IPR029033: Histidine phosphatase superfamily (homologous_superfamily) [28-445]
- IPR016274: Histidine acid phosphatase, eukaryotic (family) [1-445]
Interaction partners: - Thiamine-repressible acid phosphatase pho4
- Putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 1
- Probable metabolite transport protein C1271.09
- Putative inorganic phosphate transporter C8E4.01c
- Uncharacterized transcriptional regulatory protein C27B12.11c
- Alkaline phosphatase
- Thiamine-repressible acid phosphatase SPBC21H7.03c
- Putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 2
- Probable thiamine biosynthetic bifunctional enzyme
- Probable acid phosphatase SPBC4.06
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0016791 (phosphatase activity), GO:0003993 (acid phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006066 (alcohol metabolic process), GO:0043094 (cellular metabolic compound salvage), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006766 (vitamin metabolic process), GO:0006790 (sulfur compound metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0008655 (pyrimidine-containing compound salvage), GO:0006767 (water-soluble vitamin metabolic process), GO:0009110 (vitamin biosynthetic process), GO:0044272 (sulfur compound biosynthetic process), GO:0019438 (aromatic compound biosynthetic process), GO:0018130 (heterocycle biosynthetic process), GO:0034308 (primary alcohol metabolic process), GO:1901617 (organic hydroxy compound biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0042723 (thiamine-containing compound metabolic process), GO:0072527 (pyrimidine-containing compound metabolic process), GO:0046165 (alcohol biosynthetic process), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0042364 (water-soluble vitamin biosynthetic process), GO:0006772 (thiamine metabolic process), GO:0034309 (primary alcohol biosynthetic process), GO:0042724 (thiamine-containing compound biosynthetic process), GO:0072528 (pyrimidine-containing compound biosynthetic process), GO:0009228 (thiamine biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)