Protein: Cyclin-H (O76513)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MYPVSSQKRSWTFANEGQLMEFRVEQNSKYIESHEEEAQGRDLNEHFLTSAEERLLLKQYEIYLFDFCRRFEPTMPKCVVGTAFHYFKRFYLNNSPMDYHPKEILATCVFVACKVEEFNVSINQFVNNIKGDRNKATDIVLSNELLLIGQLNYYLTIHNPFRPIEGFLIDIKTRSNMQNPDRLRPHIDSFIDSTYYSDACLLHTPSQIALAAVLHAASREQENLDSYVTDLLFVSAREKLPGLIDAVRKIRIMVKQYQQPDREKVKAIEKKLDKCRNQANNPDSELYKERLRRLYTDEDDMPAEDASFHIADVSSDTSAMNISQ
InterPro domains: - IPR043198: Cyclin/Cyclin-like subunit Ssn8 (family) [44-274]
- IPR027081: CyclinH/Ccl1 (family) [2-306]
- IPR013763: Cyclin-like domain (domain) [62-147]
- IPR006671: Cyclin, N-terminal (domain) [63-155]
- IPR036915: Cyclin-like superfamily (homologous_superfamily) [11-278]
- IPR031658: Cyclin, C-terminal domain 2 (domain) [159-255]
Interaction partners: - Cyclin-dependent kinase 7
- CDK-activating kinase assembly factor MAT1
- General transcription factor IIH subunit 3
- General transcription factor IIH subunit 4
- General transcription and DNA repair factor IIH helicase subunit XPD
- General transcription and DNA repair factor IIH helicase/translocase subunit XPB
- General transcription factor IIH subunit
- General transcription factor IIH subunit 1
- General transcription factor IIE subunit 1
- Cyclin-dependent kinase 9
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0019222 (regulation of metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0065009 (regulation of molecular function), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0051726 (regulation of cell cycle), GO:0050790 (regulation of catalytic activity), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0044249 (cellular biosynthetic process), GO:0031323 (regulation of cellular metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0043170 (macromolecule metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:1904029 (regulation of cyclin-dependent protein kinase activity), GO:0090304 (nucleic acid metabolic process), GO:0051246 (regulation of protein metabolic process), GO:0019438 (aromatic compound biosynthetic process), GO:0018130 (heterocycle biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0051338 (regulation of transferase activity), GO:0010467 (gene expression), GO:0051174 (regulation of phosphorus metabolic process), GO:0034654 (nucleobase-containing compound biosynthetic process), GO:0000079 (regulation of cyclin-dependent protein serine/threonine kinase activity), GO:0016070 (RNA metabolic process), GO:0043549 (regulation of kinase activity), GO:0031399 (regulation of protein modification process), GO:0032774 (RNA biosynthetic process), GO:0097659 (nucleic acid-templated transcription), GO:0019220 (regulation of phosphate metabolic process), GO:0042325 (regulation of phosphorylation), GO:0001932 (regulation of protein phosphorylation), GO:0006351 (DNA-templated transcription), GO:0045859 (regulation of protein kinase activity), GO:0071900 (regulation of protein serine/threonine kinase activity), GO:0006366 (transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0140535 (intracellular protein-containing complex), GO:1902494 (catalytic complex), GO:0140513 (nuclear protein-containing complex), GO:0005667 (transcription regulator complex), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0030880 (RNA polymerase complex), GO:1990234 (transferase complex), GO:0043229 (intracellular organelle), GO:0090575 (RNA polymerase II transcription regulator complex), GO:0032806 (carboxy-terminal domain protein kinase complex), GO:0043233 (organelle lumen), GO:0055029 (nuclear DNA-directed RNA polymerase complex), GO:0016591 (RNA polymerase II, holoenzyme), GO:0043227 (membrane-bounded organelle), GO:0000428 (DNA-directed RNA polymerase complex), GO:0043231 (intracellular membrane-bounded organelle), GO:0005675 (transcription factor TFIIH holo complex), GO:0061695 (transferase complex, transferring phosphorus-containing groups), GO:0070013 (intracellular organelle lumen), GO:0005634 (nucleus), GO:1902911 (protein kinase complex), GO:0031981 (nuclear lumen), GO:1902554 (serine/threonine protein kinase complex)