wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Zinc finger CCCH domain-containing protein 2 (OsC3H2) (Protein DELAY OF THE ONSET OF SENESCENCE) (OsDOS) (Q9FU27)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Involved in leaf senescence delay. May repress jasmonic acid (JA) signaling role in promoting leaf senescence. May regulate panicle development and pollination/fertilization process.
Subcellular location: Nucleus {ECO:0000269|PubMed:16778011}.
Sequence: MMMMGEGVSSVPPWSHLPVSGVDVLGGGGGGGDEMTPYVIAALRDYLPANDVGVGADEEEEAAAMAAAVDAYACDEFRMYEFKVRRCARGRSHDWTECPFAHPGEKARRRDPRKYHYSGTACPDFRKGGCKRGDACEYAHGVFECWLHPARYRTQPCKDGTACRRRVCFFAHTPDQLRVLPAQQSSPRSVASSPLAESYDGSPLRRQAFESYLTKTIMSSSPTSTLMSPPKSPPSESPPLSPDGAAAIRRGSWPGVGSPVNDVLASFRQLRLNKVKSSPSGGWSYPSSSAVYGSPKAATGLYSLPTTPLASTATVTTASSFMPNLEPLDLGLIGDEEPVQRVESGRALREKVFERLSRDGAISGDATAFATAGVGLDVDWVSDLIN
InterPro domains: - IPR000571: Zinc finger, CCCH-type (domain) [116-174]
- IPR045234: RING finger protein Unkempt-like (family) [64-385]
- IPR057444: AtC3H23-like, CCCH zinc finger domain (domain) [76-109]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0050793 (regulation of developmental process), GO:0051241 (negative regulation of multicellular organismal process), GO:0051239 (regulation of multicellular organismal process), GO:0051093 (negative regulation of developmental process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0048581 (negative regulation of post-embryonic development), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0048580 (regulation of post-embryonic development), GO:2000026 (regulation of multicellular organismal development), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0010029 (regulation of seed germination), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:1900140 (regulation of seedling development), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Gap junction delta-3 protein (Connexin-31.9) (Cx31.9) (Gap junction alpha-11 protein) (Gap junction chi-1 protein) (Q8N144)
Organism: Homo sapiens (Human)
Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Subcellular location: Cell membrane {ECO:0000269|PubMed:12154091}; Multi-pass membrane protein {ECO:0000269|PubMed:12154091}. Cell junction, gap junction {ECO:0000269|PubMed:12154091}.
Sequence: MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEAQCAPCALRARRARRCYLLSVALRLLAELTFLGGQALLYGFRVAPHFACAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWKGRPRAGERDNRCNRAHEEAQKLLPPPPPPPPPPALPSRRPGPEPCAPPAYAHPAPASLRECGSGRGKASPATGRRDLAI
InterPro domains: - IPR000500: Connexin (family) [1-226]
- IPR017990: Connexin, conserved site (conserved_site) [168-184]
- IPR019570: Connexin, cysteine-rich domain (domain) [146-212]
- IPR038359: Connexin, N-terminal domain superfamily (homologous_superfamily) [2-222]
- IPR013092: Connexin, N-terminal (domain) [3-214]
Interaction partners: - Gap junction alpha-3 protein
- Gap junction beta-2 protein
- Gap junction alpha-8 protein
- Tight junction protein 1
- Gap junction gamma-1 protein
- Gap junction beta-4 protein
- Gap junction beta-1 protein
- Gap junction alpha-1 protein
- Gap junction alpha-5 protein
- Gap junction epsilon-1 protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015267 (channel activity), GO:0022829 (wide pore channel activity), GO:0005243 (gap junction channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007154 (cell communication), GO:0010644 (cell communication by electrical coupling)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Inactive pancreatic lipase-related protein 1 (PL-RP1) (P06857)
Organism: Canis lupus familiaris (Dog) (Canis familiaris)
Function: May function as inhibitor of dietary triglyceride digestion. Lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters (in vitro).
Subcellular location: Secreted {ECO:0000269|PubMed:9726421}.
Sequence: MVSIWTIALFLLGAAKAKEVCYEQIGCFSDAEPWAGTAIRPLKVLPWSPERIGTRFLLYTNKNPNNFQTLLPSDPSTIEASNFQTDKKTRFIIHGFIDKGEENWLLDMCKNMFKVEEVNCICVDWKKGSQTSYTQAANNVRVVGAQVAQMLSMLSANYSYSPSQVQLIGHSLGAHVAGEAGSRTPGLGRITGLDPVEASFQGTPEEVRLDPTDADFVDVIHTDAAPLIPFLGFGTSQQMGHLDFFPNGGEEMPGCKKNALSQIVDLDGIWEGTRDFVACNHLRSYKYYSESILNPDGFASYPCASYRAFESNKCFPCPDQGCPQMGHYADKFAVKTSDETQKYFLNTGDSSNFARWRYGVSITLSGKRATGQAKVALFGSKGNTHQFNIFKGILKPGSTHSNEFDAKLDVGTIEKVKFLWNNNVVNPTFPKVGAAKITVQKGEEKTVHSFCSESTVREDVLLTLTPC
InterPro domains: - IPR000734: Triacylglycerol lipase family (family) [2-420]
- IPR001024: PLAT/LH2 domain (domain) [356-467]
- IPR002331: Pancreatic lipase (family) [19-466]
- IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [18-355]
- IPR033906: Lipase, N-terminal (domain) [52-349]
- IPR016272: Lipase, LIPH-type (family) [1-467]
- IPR036392: PLAT/LH2 domain superfamily (homologous_superfamily) [354-467]
- IPR013818: Lipase (domain) [18-353]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0043167 (ion binding), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0043169 (cation binding), GO:0016298 (lipase activity), GO:0052689 (carboxylic ester hydrolase activity), GO:0046872 (metal ion binding), GO:0004806 (triglyceride lipase activity), GO:0005509 (calcium ion binding), GO:0004620 (phospholipase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0006629 (lipid metabolic process), GO:1901575 (organic substance catabolic process), GO:0044248 (cellular catabolic process), GO:0006638 (neutral lipid metabolic process), GO:0046486 (glycerolipid metabolic process), GO:0044242 (cellular lipid catabolic process), GO:0016042 (lipid catabolic process), GO:0046461 (neutral lipid catabolic process), GO:0006639 (acylglycerol metabolic process), GO:0046503 (glycerolipid catabolic process), GO:0046464 (acylglycerol catabolic process), GO:0006641 (triglyceride metabolic process), GO:0019433 (triglyceride catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Glycerophosphodiester phosphodiesterase GDPD2 (EC 3.1.4.46) (Glycerophosphodiester phosphodiesterase 2) (AtGDPD2) (Q9FLM1)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MALRTVLVSDVPSLPDSVYGLSEGLELSKPTSFRLPGFSVIGHRGIGMNVLQSSDRRARGVKENSILSFNSAAKYPIDFIEFDVQVTKDDCPVIFHDDFIYSEENGIVNESRVTDLSLSEFLLYGPQKETEKIGKTLMRKSKEGKVLKWDVDLDDSLCTLQEAFEQVEQTLGFNIELKFDDQTVYEREFLVHILRSVLQVVSNYAKDRPVIFSSFQPDAAKLVRELQSTYPVFFLTDAGNEIHNDERRNSLEEAIQVCLEGGLQGIVSEVKGVFRNPAAISKIKESNLSLLTYGKLNNVGEAVYMQYVMGIDGVIVDFVEEIIESTTRMMIRPPPSSSPLPSPSKDDDVAITRPEFSQKEISFLLKLLSQLIQH
InterPro domains: - IPR017946: PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily (homologous_superfamily) [33-326]
- IPR030395: Glycerophosphodiester phosphodiesterase domain (domain) [38-326]
- IPR051578: Glycerophosphodiester Phosphodiesterase (family) [34-329]
Interaction partners: - Probable choline kinase 2
- Probable choline kinase 3
- Probable choline kinase 1
- Glycerophosphodiester phosphodiesterase GDPD5
- Alpha/beta-Hydrolases superfamily protein
- Alpha/beta-Hydrolases superfamily protein
- Glycerophosphodiester phosphodiesterase GDPD6
- Glycerophosphodiester phosphodiesterase GDPD1, chloroplastic
- Glycerophosphodiester phosphodiesterase GDPD3
- Purple acid phosphatase 22
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0043167 (ion binding), GO:0016787 (hydrolase activity), GO:0043169 (cation binding), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0046872 (metal ion binding), GO:0008081 (phosphoric diester hydrolase activity), GO:0000287 (magnesium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0042592 (homeostatic process), GO:0051716 (cellular response to stimulus), GO:0048878 (chemical homeostasis), GO:0009628 (response to abiotic stimulus), GO:0019725 (cellular homeostasis), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0055082 (intracellular chemical homeostasis), GO:0001666 (response to hypoxia), GO:0098771 (inorganic ion homeostasis), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0070482 (response to oxygen levels), GO:0071456 (cellular response to hypoxia), GO:0055062 (phosphate ion homeostasis), GO:0071453 (cellular response to oxygen levels), GO:0030643 (intracellular phosphate ion homeostasis), GO:0036293 (response to decreased oxygen levels), GO:0036294 (cellular response to decreased oxygen levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0043231 (intracellular membrane-bounded organelle)
Protein: TIA1 cytotoxic granule-associated RNA binding protein (A0A8I6AQH6)
Organism: Rattus norvegicus (Rat)
Function: Not known
Sequence: LRQEYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVSQSSPGNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQIGYPPAYGQWGQWYGNAQQIGQYVPNGWQVPAYGMYGQPWSQQGFNQTQSSAPWMGPNYSVPPPQGQNGGMLPNQPAGYRVAGYETQ
InterPro domains: - IPR035979: RNA-binding domain superfamily (homologous_superfamily) [5-268]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [2-274]
- IPR034830: TIA-1, RNA recognition motif 2 (domain) [88-165]
- IPR000504: RNA recognition motif domain (domain) [2-270]
- IPR003954: RNA recognition motif domain, eukaryotic-type (domain) [3-266]
- IPR034496: TIAR, RNA recognition motif 3 (domain) [198-270]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0010941 (regulation of cell death), GO:0010942 (positive regulation of cell death), GO:0043067 (regulation of programmed cell death), GO:0043068 (positive regulation of programmed cell death), GO:0043065 (positive regulation of apoptotic process), GO:0042981 (regulation of apoptotic process), GO:1904037 (positive regulation of epithelial cell apoptotic process), GO:1904035 (regulation of epithelial cell apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:1990904 (ribonucleoprotein complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0035770 (ribonucleoprotein granule), GO:0036464 (cytoplasmic ribonucleoprotein granule), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0010494 (cytoplasmic stress granule), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Rubredoxin (Rd) (EC 1.-.-.-) (Q9AL94)
Organism: Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / IAM 19013 / LMG 5710 / NBRC 13948 / NRRL B-527 / VKM B-1787 / 2291 / W)
Function: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule. Functions as an intermediate component in the electron transfer chain: NADH->NROR->Rd->FprA1/2 in which Rd serves as the proximal electron donor to the FDPs that exhibit H(2)O-forming NADH oxidase activity. Also functions as the proximal electron donor to the Dfx and revRbr proteins that display superoxide reductase (SOR) and NADH peroxidase activity, respectively. Therefore, is a key electron carrier in an efficient multienzyme complex that can scavenge O(2) and reactive oxygen species (ROS), and thus plays an important role in the oxidative stress defense system in C.acetobutylicum, an obligate anaerobic bacterium.
Sequence: MKKYVCVVCGYIYDPAEGDPDNGVNPGTSFEDIPDDWVCPLCGVGKDQFEPSEE
InterPro domains: - IPR018527: Rubredoxin, iron-binding site (binding_site) [33-43]
- IPR024922: Rubredoxin (family) [1-54]
- IPR024934: Rubredoxin-like domain (domain) [1-52]
- IPR024935: Rubredoxin domain (domain) [3-52]
- IPR050526: Rubredoxin electron transfer (family) [1-53]
Interaction partners: - NADH-rubredoxin oxidoreductase
- Desulfoferrodoxin
- Glutaredoxin
- BFD-like [2Fe-2S]-binding domain-containing protein
- Flavo-diiron protein FprA2
- Flavo-diiron protein FprA1
- Rubrerythrin-1
- Rubrerythrin-2
- Reverse rubrerythrin-1
- Reverse rubrerythrin-2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009056 (catabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:1901575 (organic substance catabolic process), GO:0120252 (hydrocarbon metabolic process), GO:0044248 (cellular catabolic process), GO:0120253 (hydrocarbon catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: NTPase, isoform C (EC 3.6.1.42, EC 3.6.1.6, EC 3.6.1.64) (NTPase, isoform D) (Q8IPZ6)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MDAVEIMDGTDEGIFSWFTVNFLLGRLSKTNQAAALDLGGGSTQVTFSPTDPDQVPVYDKYMHEVVTSSKKINVFTHSYLGLGLMAARHAVFTHGYKKEDTVLESVCVNPIIANRTWTYGNVQYKVSGKENGKSSAEQPIVDFDACLELVKSKVMPLVKPKPFTLKQHAVAAFSYYFERAIESGLVDPLAGGETTVEAYRKKAQEICAIPNDEQPFMCFDLTFISTLLREGFGLNDGKKIKLYKKIDGHEISWALGCAYNVLTSDEKFSNS
InterPro domains: - IPR000407: Nucleoside phosphatase GDA1/CD39 (family) [2-265]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity), GO:0017110 (nucleoside diphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0042742 (defense response to bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Odorant receptor 33a (P81914)
Organism: Drosophila melanogaster (Fruit fly)
Function: Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates. The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration. May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability (By similarity).
Subcellular location: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Sequence: MDSRRKVRSENLYKTYWLYWRLLGVEGDYPFRRLVDFTITSFITILFPVHLILGMYKKPQIQVFRSLHFTSECLFCSYKFFCFRWKLKEIKTIEGLLQDLDSRVESEEERNYFNQNPSRVARMLSKSYLVAAISAIITATVAGLFSTGRNLMYLGWFPYDFQATAAIYWISFSYQAIGSSLLILENLANDSYPPITFCVVSGHVRLLIMRLSRIGHDVKLSSSENTRKLIEGIQDHRKLMKIIRLLRSTLHLSQLGQFLSSGINISITLINILFFAENNFAMLYYAVFFAAMLIELFPSCYYGILMTMEFDKLPYAIFSSNWLKMDKRYNRSLIILMQLTLVPVNIKAGGIVGIDMSAFFATVRMAYSFYTLALSFRV
InterPro domains: - IPR004117: Olfactory receptor, insect (family) [32-373]
Interaction partners: - Odorant receptor 47a
- Odorant receptor 56a
- Putative odorant receptor 69a, isoform A
- Odorant receptor 30a
- Putative gustatory receptor 59c
- Odorant receptor 85b
- Odorant receptor 65a
- Odorant receptor 74a
- Odorant receptor 67b
- Odorant receptor 82a
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0004984 (olfactory receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0032501 (multicellular organismal process), GO:0051606 (detection of stimulus), GO:0042221 (response to chemical), GO:0003008 (system process), GO:0050877 (nervous system process), GO:0009593 (detection of chemical stimulus), GO:0050906 (detection of stimulus involved in sensory perception), GO:0050907 (detection of chemical stimulus involved in sensory perception), GO:0007600 (sensory perception), GO:0007606 (sensory perception of chemical stimulus), GO:0050911 (detection of chemical stimulus involved in sensory perception of smell), GO:0007608 (sensory perception of smell)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)
Protein: D-arabinitol 2-dehydrogenase [ribulose-forming] (ARDH) (EC 1.1.1.250) (P50166)
Organism: Candida tropicalis (Yeast)
Function: Catalyzes the NAD(+)-dependent oxidation of D-arabinitol at carbon 4 to produce D-ribulose.
Sequence: MDSSSYWSYDNIVPSFRLDGKLVIITGGSGGLSAVVSRALLAKGADIALIDMNLERTQQAARDVLQWGEEQMKGKHESPIGQVSAWSCNIGDAEAVELTFKAINEHHGKVASVLINTAGYAENFPAEEYPAKNAENIMKVNGLGSFYVSQAFARPLIQNNMTGSIILIGSMSGTIVNDPQPQCMYNMSKAGVIHLARSLACEWAKYNIRVNTLSPGYILTPLTRNVISGHTEMKTEWESKIPMKRMAEPKEFVGSILYLASDSASSYTTGHNLVVDGGYECW
InterPro domains: - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [7-281]
- IPR020904: Short-chain dehydrogenase/reductase, conserved site (conserved_site) [172-200]
- IPR002347: Short-chain dehydrogenase/reductase SDR (family) [22-279]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044282 (small molecule catabolic process), GO:0044248 (cellular catabolic process), GO:0019637 (organophosphate metabolic process), GO:0006066 (alcohol metabolic process), GO:0005996 (monosaccharide metabolic process), GO:0005975 (carbohydrate metabolic process), GO:1901575 (organic substance catabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0006793 (phosphorus metabolic process), GO:0044262 (cellular carbohydrate metabolic process), GO:0044275 (cellular carbohydrate catabolic process), GO:0019321 (pentose metabolic process), GO:1901616 (organic hydroxy compound catabolic process), GO:0046365 (monosaccharide catabolic process), GO:0046164 (alcohol catabolic process), GO:0019400 (alditol metabolic process), GO:0019751 (polyol metabolic process), GO:0090407 (organophosphate biosynthetic process), GO:0006796 (phosphate-containing compound metabolic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0016052 (carbohydrate catabolic process), GO:0019405 (alditol catabolic process), GO:0019323 (pentose catabolic process), GO:0046174 (polyol catabolic process), GO:0019566 (arabinose metabolic process), GO:0019568 (arabinose catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0005773 (vacuole), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)