Protein: Hedgehog acyltransferase-like, a (Q6P3I5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Membrane; Multi- pass membrane protein
Sequence: MGIKAALPRIELYIYTAVLGLALLWAASWIIEASSENVNRRAFRENVKPGWHYFGRRMDVSDFEWVMWFTTFRNHILFALSGHVIFAKICSMLSPKNRSLIYMMYGALAVLITMGWTYISLILSHCIVLYSVALVKKKWLCFVAGLTSLATFKMEPFSGWQEGFVTGSFDLQDILFYGGCGFSIMRCMSFALENCEKKDGNYSFMDLIKYNFYLPFFFFGPVMTFDRFHEQANNPNLTRKEREMWNITIHALVHLGAILVVDVFFHFLYILTIPGDLKLLKQLSDWSLAGLAYSNLVYDWVKAAVMFGVINTVSRLDHLDPPQPPKCITMLYVFAETHFDRGINDWLCKYVYDYIGENHDSIIKELLATICTFAVTTLWLGPCDIVYIWSFFNCFGLNFELWVAKLFSLPPFSTIENNLMSEAMSRRIRGLFNAVNFWQIILYNVLALNSLDFAQLVAKRLLLKGFPLSTLSVLFVTYCGVQLIKERERKQALLDDPEPVPPPEAGKPKAE
InterPro domains: - IPR051085: Membrane-bound O-acyltransferase (family) [4-490]
- IPR004299: Membrane bound O-acyl transferase, MBOAT (family) [129-413]
Interaction partners: - Beta-alanine-activating enzyme
- Acyl carrier protein
- NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0008374 (O-acyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0048523 (negative regulation of cellular process), GO:0009892 (negative regulation of metabolic process), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0051252 (regulation of RNA metabolic process), GO:0051253 (negative regulation of RNA metabolic process), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:0010468 (regulation of gene expression), GO:2001141 (regulation of RNA biosynthetic process), GO:1902679 (negative regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903507 (negative regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045892 (negative regulation of DNA-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)