Protein: Probable RNA-directed DNA polymerase from transposon BS (EC 2.7.7.49) (Reverse transcriptase) (Q95SX7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MNPLKILIWNANGISRKAKDVELFAHNKKVDILLVTELRLKRGETVKIYGYAYYPAYRPSLNNNSVGGVAVFVRTTLRHFPQRVIETRHIQLSSVKVATGLGDLQFSAIYCSPSTRIEERHFTDIIRACGQRYLVGGDWNARHWLWGDTCNSPRGRELAEALSVTGAKILATGSPTRYPYVPSHTPSCIDFAVYHGIPDHLATITQSWDLDSDHLPLIISIETDSTHVNPSPRLVTKHTDLLAFSRQLESLISLNTTLNSGEEIEMAVDNLTESIHRAAAVSTSPVPRIGTTYGIVLTREARELLTQKRRLRRRAIRSQDPWDRLLWNRAAKQLRNVLRELRSNFFEQKLASMDYTVDAGYSLWKCTKSLKRQPFRQVPIRCPGGELAKNEEEQANCFANHLETRFTHFQFATTEQYQETLDSLETPLQMSLPIKPIRVEEIVEAIKSLPLKKSPGIDNVCNATLKALPVRAILYLALIYNAILRVQFFPKQWKMAAILMIHKPGKPEESPESYRPISLLSSLSKLWERLIANRLNDIMTERRILPDHQFGFRQGHSTVEQVHRLTKHILQAFDDKEYCNAVFIDMQQAFDRVWHDGLISKVKKLFPAPYYGVLKSYLEDRRFMVRVRNSYSIPRVMRAGVPQGSVLGPLLYSVFTADLPCPNAYHMADPRKALLATYADDIALLYSSNCCNEAARGLQEYLTTLAAWCKRWILKVNPQKTINPCFTLKTLSPVTAPIELEGVILDQPSQAKYLGITLDKRLTFGPHLKATTRRCYQRMQQLRWLLNRKSTMTLRAKRAVYVHCVAPIWLYGIQIWGIAAKSNYNRIQVLQNRAMRAITDCPYYVRGTTLHRDLNLHTVEEQISRHTSRYSDRLRRHHSILARRLLPARPLRRLKRKGFAKTLGQP
InterPro domains: - IPR043502: DNA/RNA polymerase superfamily (homologous_superfamily) [428-726]
- IPR000477: Reverse transcriptase domain (domain) [482-758]
- IPR052560: RNA-directed DNA polymerase, mobile element (family) [9-786]
- IPR005135: Endonuclease/exonuclease/phosphatase (domain) [9-214]
- IPR036691: Endonuclease/exonuclease/phosphatase superfamily (homologous_superfamily) [3-223]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016740 (transferase activity), GO:0140097 (catalytic activity, acting on DNA), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0034061 (DNA polymerase activity), GO:0016779 (nucleotidyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0032196 (transposition), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0006259 (DNA metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0006310 (DNA recombination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:1902494 (catalytic complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0140535 (intracellular protein-containing complex), GO:0043229 (intracellular organelle), GO:1905348 (endonuclease complex), GO:0043227 (membrane-bounded organelle), GO:1902555 (endoribonuclease complex), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)