Protein: Pumilio homolog 1 (A0A0R4IWL6)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cytoplasm, P-body. Cytoplasmic granule
Sequence: MSVACVLKRKAVLWQDSFSPHLRLPPPDRPLPSMPVVLSAAGHTPQPGPSPQAPAPTQGAGRSQDDAMVDYFFQRQHGDQPGYNNCKHRWPTGDNIHADNQVRSMDELNHDFQALALEGRAMGEQLLTGKKFWETDDSGKDGPKGIFLDQWRDSAWGASDHSVSQPIMVQRRPGQGFHGVGEAGSVLSPRSESGGLGVSMVEYVLSSSPAEKMDSCLRKGAYGPRDSEADDPEKRVEQKPKTTFDPERKELKETEPDVLDNPNGLPNQNGLDVDVKDFSRTPGNCPPTGQEVELGGPEMVGGAGPKPAEEFSNVETQNVTLDPMESVSMETLQFEYPGGQLPLDSTAATVGLFDYNSPQQLFQRPNALAVQQLTAAQQQQYALAAAQQPHIGLAPAAFVPNPYIISAAPPGTDPYAAGLAAAATLGPAVMPPQYYGVTPWGVYPANLFQQQAATPSNSANQQSAAQNQQNQQQVMRAGGNQRPLTPSQGQQGQQTEQLVAAAAVNSALAFGQGLAAGVPGYPVLAPAAYYDQTGALVVNTGARGGPVRLMAPASVIISPSAAVAAAAASAGGANAGLGGGASGAFRALSSQQAPGQQGSGALGGSSFYGSGSPSSSSQSSSLFSQGSAQPGNTSLGFNANPTSSLGATLGAALGGFGTAVANSSSSGSRRDSLTGSSDLYKRTASSLTPIGHGAFYNGLSFSSSPGPVGMPLPNQGPSHSLTPPPSLSTHGSSSSLNLGGLTNGSGRFISAAPGAEAKYRSATTGSSLFSPSSQLFPSSRLRYGMSDVMPSGRSRLLEDFRNNRYPNLQLREIAGHVMEFSQDQHGSRFIQLKLERASPAERQLVFNEILQAAYQLMVDVFGNYVIQKFFEFGSLDQKLALAERIRGHVLSLALQMYGCRVIQKALEFIPSDQQVINEMVRELDGHVLKCVKDQNGNHVVQKCIECVQPHALQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPEQTLSILEEIHQHTEQLVQDQYGNYVIQHVLEHGRAEDKSKIVSEIRGNVLGLSQHKFASNVVEKCVTHSLRAERAMLIDEVCSMADGPHSALYTMMKDQYANYVVQKMIDVAEPTQRKIVMHKIRPHIATLRKYTYGKHILAKLEKYYMKNGVDLGPLCAPPNGIM
InterPro domains: - IPR033133: Pumilio homology domain (domain) [792-1134]
- IPR016024: Armadillo-type fold (homologous_superfamily) [793-1131]
- IPR011989: Armadillo-like helical (homologous_superfamily) [791-1142]
- IPR001313: Pumilio RNA-binding repeat (repeat) [812-1110]
- IPR033712: Pumilio, RNA binding domain (domain) [807-1130]
Interaction partners: - Nanos homolog 1
- Clathrin interactor 1 isoform X1
- SH3 domain-containing 19
- Cytochrome c oxidase copper chaperone
- CCR4-NOT transcription complex subunit 7
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0022414 (reproductive process), GO:0009987 (cellular process), GO:0032502 (developmental process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0019953 (sexual reproduction), GO:0051641 (cellular localization), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0007389 (pattern specification process), GO:0007316 (pole plasm RNA localization), GO:0071840 (cellular component organization or biogenesis), GO:0021700 (developmental maturation), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0033036 (macromolecule localization), GO:0007276 (gamete generation), GO:0007281 (germ cell development), GO:0007309 (oocyte axis specification), GO:0009798 (axis specification), GO:0044085 (cellular component biogenesis), GO:0006403 (RNA localization), GO:0003002 (regionalization), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048469 (cell maturation), GO:0070727 (cellular macromolecule localization), GO:0060810 (intracellular mRNA localization involved in pattern specification process), GO:0007315 (pole plasm assembly), GO:0007308 (oocyte construction), GO:0016043 (cellular component organization), GO:0009994 (oocyte differentiation), GO:0009790 (embryo development), GO:0019094 (pole plasm mRNA localization), GO:0009880 (embryonic pattern specification), GO:0071695 (anatomical structure maturation), GO:0035282 (segmentation), GO:0007314 (oocyte anterior/posterior axis specification), GO:0008298 (intracellular mRNA localization), GO:0007292 (female gamete generation), GO:0048599 (oocyte development), GO:0048477 (oogenesis), GO:0007028 (cytoplasm organization), GO:0060811 (intracellular mRNA localization involved in anterior/posterior axis specification), GO:0000578 (embryonic axis specification), GO:0007350 (blastoderm segmentation), GO:0007351 (tripartite regional subdivision), GO:0009952 (anterior/posterior pattern specification), GO:0009948 (anterior/posterior axis specification), GO:0022607 (cellular component assembly), GO:0008595 (anterior/posterior axis specification, embryo), GO:0008358 (maternal determination of anterior/posterior axis, embryo)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)