Protein: 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51) (A0A024RCV5)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MDLWPGAWMLLLLLFLLLLFLLPTLWFCSPSAKYFFKMAFYNGWILFLAVLAIPVCAVRGRNVENMKILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVSNHQSSLDLLGMMEVLPGRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGQCQVRVLPPVPTEGLTPDDVPALADRVRHSMLTVFREISTDGRGGGDYLKKPGGGG
InterPro domains: - IPR002123: Phospholipid/glycerol acyltransferase (domain) [83-213]
- IPR004552: 1-acyl-sn-glycerol-3-phosphate acyltransferase (domain) [81-210]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0008374 (O-acyltransferase activity), GO:0071617 (lysophospholipid acyltransferase activity), GO:0016411 (acylglycerol O-acyltransferase activity), GO:0042171 (lysophosphatidic acid acyltransferase activity), GO:0003841 (1-acylglycerol-3-phosphate O-acyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023056 (positive regulation of signaling), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0048584 (positive regulation of response to stimulus), GO:0019222 (regulation of metabolic process), GO:0051240 (positive regulation of multicellular organismal process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0009893 (positive regulation of metabolic process), GO:0023051 (regulation of signaling), GO:0051239 (regulation of multicellular organismal process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0060759 (regulation of response to cytokine stimulus), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0010646 (regulation of cell communication), GO:0019637 (organophosphate metabolic process), GO:0009966 (regulation of signal transduction), GO:0044255 (cellular lipid metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010647 (positive regulation of cell communication), GO:0060760 (positive regulation of response to cytokine stimulus), GO:0044249 (cellular biosynthetic process), GO:0001819 (positive regulation of cytokine production), GO:0001817 (regulation of cytokine production), GO:0006793 (phosphorus metabolic process), GO:0001961 (positive regulation of cytokine-mediated signaling pathway), GO:0046486 (glycerolipid metabolic process), GO:0001959 (regulation of cytokine-mediated signaling pathway), GO:0006644 (phospholipid metabolic process), GO:0090407 (organophosphate biosynthetic process), GO:0010628 (positive regulation of gene expression), GO:0006796 (phosphate-containing compound metabolic process), GO:0008610 (lipid biosynthetic process), GO:0010468 (regulation of gene expression), GO:0045017 (glycerolipid biosynthetic process), GO:0006650 (glycerophospholipid metabolic process), GO:0008654 (phospholipid biosynthetic process), GO:0046474 (glycerophospholipid biosynthetic process), GO:0006654 (phosphatidic acid biosynthetic process), GO:0046473 (phosphatidic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0031090 (organelle membrane), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098827 (endoplasmic reticulum subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0005789 (endoplasmic reticulum membrane)