Protein: S-adenosylmethionine-homocysteine S-methyltransferase (A0A1D8PEB0)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Sequence: MGRVQDILEKRKLVIDGALGTELERLLPTTSTYLPSGSPLWSGQVLIKNPGLVEQVHLDYINVGADMIITSTYQTSYASLHKYIGYDMDQAIALWNSALNVAKNAVKKSGRDDVIIAGSIGPYATLLANGSEYNGDYQGVTDEELIEYHTPLFEFYENSDVDIICIETIPSFQELKVIIGLAKKYTSKEFFISINPQTGSALSDGTSLIEVAQLFAEINDPRFVAVGINCTSYENVDQISTYLTDFPLFIYPNLGFVYDTTVHKFVSKVLQESTWSKSVAKWLAFPNVKAIGGCCSTTPAEIKQVAQLINQ
InterPro domains: - IPR051486: Homocysteine S-methyltransferase (family) [9-310]
- IPR003726: Homocysteine-binding domain (domain) [1-309]
- IPR036589: Homocysteine-binding domain superfamily (homologous_superfamily) [2-310]
Interaction partners: - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
- S-adenosylmethionine synthase
- Adenosylhomocysteinase
- Cystathionine beta-synthase
- cystathionine gamma-synthase
- Cystathionine beta-lyase
- aromatic-amino-acid transaminase
- Homoserine dehydrogenase
- Homocysteine/cysteine synthase
- Homoserine kinase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0008168 (methyltransferase activity), GO:0008757 (S-adenosylmethionine-dependent methyltransferase activity), GO:0008172 (S-methyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006575 (cellular modified amino acid metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044283 (small molecule biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0006082 (organic acid metabolic process), GO:0046500 (S-adenosylmethionine metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006520 (amino acid metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0043094 (cellular metabolic compound salvage), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006790 (sulfur compound metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0000096 (sulfur amino acid metabolic process), GO:0044272 (sulfur compound biosynthetic process), GO:0043436 (oxoacid metabolic process), GO:0008652 (amino acid biosynthetic process), GO:0016053 (organic acid biosynthetic process), GO:0009116 (nucleoside metabolic process), GO:1901657 (glycosyl compound metabolic process), GO:0072521 (purine-containing compound metabolic process), GO:0043102 (amino acid salvage), GO:1901605 (alpha-amino acid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0071267 (L-methionine salvage), GO:1901607 (alpha-amino acid biosynthetic process), GO:0009066 (aspartate family amino acid metabolic process), GO:0000097 (sulfur amino acid biosynthetic process), GO:0046394 (carboxylic acid biosynthetic process), GO:0042278 (purine nucleoside metabolic process), GO:0006555 (methionine metabolic process), GO:0009119 (ribonucleoside metabolic process), GO:0046128 (purine ribonucleoside metabolic process), GO:0009086 (methionine biosynthetic process), GO:0009067 (aspartate family amino acid biosynthetic process), GO:0071265 (L-methionine biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062039 (biofilm matrix), GO:0062040 (fungal biofilm matrix)