Protein: Transcriptional regulator IFH1 (Q5AG97)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Transcriptional coactivator that together with FHL1 regulates the expression of rRNA and ribosomal protein genes. The FHL1-IFH1 complex is targeted to the ribosomal protein genes by the DNA-binding factor TBF1
Subcellular location: Nucleus
Sequence: MGYKNSDNTNNKFSRKSMSPSLTGGKGRKTVGKKVKKTIPRKTVNWSSYDVNSDSNEDSDEESENENDSDNDDEDDDETEHHHLDGLYSLMGKRPHDSSSNGDDDDDDDDDNDNKNIFSSTSSDGDSDEAMFSSSDDDSDVDFVKLQAQQKAHALKIAKARKGLKSKPKNESNDNAIASSSESESNSESDNEDDDDDVVSLKKLKPRKKSFLKYGRRRSDAVLPDINFKFEFDTGENDELEAGNQETHIKEPEEEDIGEEVDYSPENPVDSNNVPSLEFEFDHHLIEVPKINEEELNSDEDYEIDDNELLATLQAENDAEEFLPPITKGNSQPQRNDSLISSTIEEEENDNDNEEASKGGDGDDDDDDDDDENDPFLKEEEKYLVNEFETNGFDENEEDEDEDDLHTFDSDFSTTNRIVNSFKGIGEDRSKPIVKYESSVSGGSDYDEDDYIDLINFDVPLFDDKNGHLDGGKKNSHHKGNTDKLKKDKVKQRANSNHNSDEDDDSYLWNYFFSSDNDSSSEETDDKNNSKTVNKSRKNKKNKKALTNNAITGADELFEQIENDNTFKSKSKSNHHGNSLYKAYSDSPMTIQDLEAEIRAGADDDDDDDDDYDSSESTDVDESLPKSSSNNSLVGSSKKATEVLSSKTADYRPPKLGSWVTVDCKPFGVIDGLSTRTLQLNKSQEPRSAAQSGTSHSTSIVNSSNGSGLGLPTTSIASSLAANPRKSIVVGPTNVPSSMISSDDSALGLDELLNVSELDNDDENDVKIWRDFNNNQNKKKIPLGAFRNKSVLYNNHIYQDDQHHHLHRRNSNADKKFNGSGHIKKQQPIRRQSQSKIERRRASIVEAVSQGYRPTKSGLFSETALADVEELLGDDRDLMELIQGL
InterPro domains: - IPR018837: Transcription factor CRF1/IFH1 (family) [1-876]
Interaction partners: - Transcription factor TBF1
- Transcriptional regulator HMO1
- Fork-head transcriptional regulator FHL1
- U3 small nucleolar RNA-associated protein 22
- Zinc-coordinating transcription factor
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0140678 (molecular function inhibitor activity), GO:0060589 (nucleoside-triphosphatase regulator activity), GO:0005085 (guanyl-nucleotide exchange factor activity), GO:0030695 (GTPase regulator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0009628 (response to abiotic stimulus), GO:0042221 (response to chemical), GO:0071554 (cell wall organization or biogenesis), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0030447 (filamentous growth), GO:0071840 (cellular component organization or biogenesis), GO:0006950 (response to stress), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0040008 (regulation of growth), GO:0009408 (response to heat), GO:0009266 (response to temperature stimulus), GO:0044182 (filamentous growth of a population of unicellular organisms), GO:0071852 (fungal-type cell wall organization or biogenesis), GO:0104004 (cellular response to environmental stimulus), GO:0035556 (intracellular signal transduction), GO:0006979 (response to oxidative stress), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0071214 (cellular response to abiotic stimulus), GO:0010570 (regulation of filamentous growth), GO:0006970 (response to osmotic stress), GO:0016043 (cellular component organization), GO:0071555 (cell wall organization), GO:0034599 (cellular response to oxidative stress), GO:0031505 (fungal-type cell wall organization), GO:0036177 (filamentous growth of a population of unicellular organisms in response to pH), GO:0062197 (cellular response to chemical stress), GO:0071470 (cellular response to osmotic stress), GO:0000165 (MAPK cascade), GO:0071470 (cellular response to osmotic stress), GO:0009651 (response to salt stress), GO:1900428 (regulation of filamentous growth of a population of unicellular organisms), GO:0045229 (external encapsulating structure organization), GO:0031098 (stress-activated protein kinase signaling cascade), GO:0036178 (filamentous growth of a population of unicellular organisms in response to neutral pH), GO:0036244 (cellular response to neutral pH)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:0140513 (nuclear protein-containing complex), GO:0031974 (membrane-enclosed lumen), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005694 (chromosome), GO:0005634 (nucleus)