Protein: Guanine deaminase (Guanase) (EC 3.5.4.3) (Guanine aminohydrolase) (Q2UHY8)
Organism: Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold)
Function: Not known
Sequence: MTTKTAQVFHGTLIHSKDPQTLEILPNTLLIISATGQIQSLHPSTNPTDIPTLLTQANHNPDTTPITTLSATEFLIPGFIDTHTHAPQWSQRGLGRGIDLLTWLEQITFAHEAKLSDPIYAKQLYRAAVQGSLKQGITTACYYGSRHKDASIILAETCLAIGQRALIGKCNMNRHAPDWYVDSSVDESVSDTVEFIAKVKELDGDTGLVTPVITPRFAITCDETLLSQLGTIVKQNPGIPVQTHFNESHGEVNFTRDLFPQFKNETELYDNYGLLTNRTILAHAIYPQPEEFPRLKELDCGVAHCPIPNTTMDEFMIAPVREYLSRGIKVGLGTDCGGGYSSSMLDVMRAAFMVSVAKQTETEGKDAPLSVAESFYLATLGGARVAGLEDRVGRFAPGLEFDACLVRTGVAEGIMAPVEEEDGVEGVFEKFLMTGDDRNIVRVWVRGREVKGSSSA
InterPro domains: - IPR051607: Metallo-dependent Hydrolases (family) [3-453]
- IPR011059: Metal-dependent hydrolase, composite domain superfamily (homologous_superfamily) [9-448]
- IPR014311: Guanine deaminase (family) [23-447]
- IPR006680: Amidohydrolase-related (domain) [74-450]
- IPR032466: Metal-dependent hydrolase (homologous_superfamily) [77-393]
Interaction partners: - xanthine dehydrogenase
- adenine phosphoribosyltransferase
- Probable guanine deaminase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0019239 (deaminase activity), GO:0016814 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0019748 (secondary metabolic process), GO:0071704 (organic substance metabolic process), GO:0044550 (secondary metabolite biosynthetic process), GO:0042180 (cellular ketone metabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0120254 (olefinic compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006066 (alcohol metabolic process), GO:0009404 (toxin metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:0006790 (sulfur compound metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0043385 (mycotoxin metabolic process), GO:0120255 (olefinic compound biosynthetic process), GO:0009403 (toxin biosynthetic process), GO:1902644 (tertiary alcohol metabolic process), GO:0044272 (sulfur compound biosynthetic process), GO:0019438 (aromatic compound biosynthetic process), GO:0018130 (heterocycle biosynthetic process), GO:0034308 (primary alcohol metabolic process), GO:1901617 (organic hydroxy compound biosynthetic process), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0042181 (ketone biosynthetic process), GO:0046165 (alcohol biosynthetic process), GO:0030639 (polyketide biosynthetic process), GO:0018958 (phenol-containing compound metabolic process), GO:0043386 (mycotoxin biosynthetic process), GO:1902645 (tertiary alcohol biosynthetic process), GO:1902653 (secondary alcohol biosynthetic process), GO:0046189 (phenol-containing compound biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)