Protein: EHS-1 (Eps15 (Endocytosis protein) Homologous Sequence) (Q9BIF4)
Organism: Caenorhabditis elegans
Function: Not known
Sequence: MDDSYAIATPHNDVFNHAFAEMNPHGAPRIGAAEAATFLKKSNLAMPVLGQIWELSDSQKVGSLDKRGAFVAFKLVAAAQQGKPVANSSLYDSSLQPPRFAPPVPPANMQHHFQPSFPSVGRAPPVPPPPHPSHPYSISSQQSSPAHPSSAFPPQWPITPTDQAKYDSIFQSLNPVNGKLSGAHVRPVLMNSGLDAHALARIWELSDQDKDGNLDRIEMSVALHLVYRSLQSDPVPAQLPPNLIHPSKAMYAHSSPNFAAPPHPPRPMMGSRAGSVTSLDDVNMSQSYSATMPRAYPPQPGRAYSAQAHVNGSRTSGASTPISASHSIHSFPAGEWPINTGDYADQFAQTDTNKDGLVDGMDMRAPMMTTGLSAQILAHVWALADIKKCGQLNLEQFALTMHLLDMAKRGESIPSELPLHLIPPSFRPPTEPSALHHPAQSVSTPQLPEATSMEIKEALEGENEEMKQLAESIQSMLVERKTAEEAVLQLEADMTIKNSSIKNLQVELATLESTVKQLERQKGEATRRLADYDTQIEQLESACKAQKETKEDTEKRMQQIDEDAKNAEDCKANDEKEMEELKKEIEMLDNQFKTVRGEIVKETSQREQKVAELTTLERKEARDQIQMEKLDAAIENTTKLTEQVSDAVEKSEEEMVQILRSQQRLLSTVIDQSLLSDDTVYGETAGTSSQNHVQQPPDPFASARANPAADPFAQVDQFGSSGHFDAAFPTDPFAQGGFPSDSGFAQSAPAKPAPPRPAPPKSARETPVNDPFAPSQGQSTQPAGFADFADFGSAFN
InterPro domains: - IPR011992: EF-hand domain pair (homologous_superfamily) [11-427]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [207-219]
- IPR002048: EF-hand domain (domain) [194-229]
- IPR000261: EH domain (domain) [4-428]
Interaction partners: - Intersectin-1
- ENTH domain-containing protein
- FCH domain only protein 2
- AP-2 complex subunit alpha
- Clathrin light chain
- Putative stoned B-like protein
- Receptor tyrosine-protein kinase let-23
- Hepatocyte growth factor-regulated tyrosine kinase substrate
- Phosphatidylinositol-binding clathrin assembly protein unc-11
- Probable clathrin heavy chain 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0050789 (regulation of biological process), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0050793 (regulation of developmental process), GO:0065008 (regulation of biological quality), GO:0040008 (regulation of growth), GO:0050794 (regulation of cellular process), GO:0051649 (establishment of localization in cell), GO:0050803 (regulation of synapse structure or activity), GO:0048638 (regulation of developmental growth), GO:0051128 (regulation of cellular component organization), GO:0006810 (transport), GO:0044087 (regulation of cellular component biogenesis), GO:0036465 (synaptic vesicle recycling), GO:0099504 (synaptic vesicle cycle), GO:0016192 (vesicle-mediated transport), GO:0008582 (regulation of synaptic assembly at neuromuscular junction), GO:0140238 (presynaptic endocytosis), GO:0050807 (regulation of synapse organization), GO:1901888 (regulation of cell junction assembly), GO:0051963 (regulation of synapse assembly), GO:0048488 (synaptic vesicle endocytosis), GO:0006897 (endocytosis), GO:0099003 (vesicle-mediated transport in synapse), GO:1904396 (regulation of neuromuscular junction development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0045178 (basal part of cell), GO:0043226 (organelle), GO:0045177 (apical part of cell), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0012505 (endomembrane system), GO:0009925 (basal plasma membrane), GO:0098590 (plasma membrane region), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0045202 (synapse), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0016324 (apical plasma membrane), GO:0005769 (early endosome), GO:0030139 (endocytic vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0045335 (phagocytic vesicle), GO:0097708 (intracellular vesicle)