wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Secreted protein CSS1 (Condition specific secretion protein 1) (Haze protective factor 1') (P40442)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Secreted protein that may be involved in cell wall organization and biosynthesis.
Subcellular location: Secreted {ECO:0000269|PubMed:26928762}.
Sequence: MFNRLNKFQAALALALYSQSALGQYYSNSTSISSNSSSTSVVSSSSGSVSISSSIAETSSSATDILSSITQSASSTSGVSSSVGPSSSSVVSSSVSQSSSSVSDVSSSVSQSSSSASDVSSSVSQSASSTSDVSSSVSQSSSSASDVSSSVSQSSSSASDVSSSVSQSASSASDVSSSVSQSASSTSDVSSSVSQSSSSASDVSSSVSQSSSSASDVSSSVSQSASSTSDVSSSVSQSASSTSGVSSSGSQSVSSASGSSSSFPQSTSSASTASGSATSNSLSSITSSASSASATASNSLSSSDGTIYLPTTTISGDLTLTGKVIATEGVVVAAGAKLTLLDGDKYSFSADLKVYGDLLVKKSKETYPGTEFDISGENFDVTGNFNAEESAATSASIYSFTPSSFDNSGDISLSLSKSKKGEVTFSPYSNSGAFSFSNAILNGGSVSGLQRRDDTEGSVNNGEINLDNGSTYVIVEPVSGKGTVNIISGNLYLHYPDTFTGQTVVFKGEGVLAVDPTETNATPIPVVGYTGKNQIAITADITALSYDGTTGVLTATQGNRQFSFAIGTGFSSSDFSVSEGIFAGAYAYYLNYNGVVATSAASSSTASGASASVTGSTSFGASVTGSTASTSFGASVTGSTASTSFGASVTGSTSVYTTTLDYVNATSTVVVSCSETTDSNGNVYTITTTVPCSSTTATITSCDETGCHVSTSTGAVVTETVSSKSYTTATVTHCDDNGCNTKTVTSECSKETSATTASPKSYTTVTVTHCDDNGCNTKTVTSEAPEATTTTTVSSQSYTTATVTHCDDNGCKTKTVTSEAPEATTTTVSPKTYTTATVTQCDDNGCSTKTVTSECPEETSATTTSPKSYTTVTVTHCDDNGCNTKTVTSEAPEATTTTVSPKTYTTATVTQCDDNGCSTKTVTSEAPKETSETSETSAAPKDIHYCHWLLNGDDNGCNVKIITSKIPEATSTVTQLVLLQSHTLLSLLRVLKQPH
InterPro domains: - IPR004089: Methyl-accepting chemotaxis protein (MCP) signalling domain (domain) [26-253]
- IPR000727: Target SNARE coiled-coil homology domain (domain) [92-154]
- IPR021031: Hyphally-regulated cell wall protein, N-terminal (domain) [312-600]
Interaction partners: - Haze protective factor 1
- Uncharacterized protein YOL160W
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0071554 (cell wall organization or biogenesis), GO:0071555 (cell wall organization), GO:0016043 (cellular component organization), GO:0071852 (fungal-type cell wall organization or biogenesis), GO:0045229 (external encapsulating structure organization), GO:0031505 (fungal-type cell wall organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005576 (extracellular region), GO:0005618 (cell wall), GO:0009277 (fungal-type cell wall)
Protein: Csh1p (Q59QH2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Sequence: MVTRLGKSGLKVNTVAVGTMRLGSSWRGFNGDIDECLKILKFCYDNGFRTFDTADTYSNGKSEELLGLFIKKYNIPRERIVILTKCYFSVKDDAEDSSLEIDPIDYMNGKGLSRKHILAAAEASVKRLGTYIDVLQIHRLDHEVTYEEVMRSLNDVVEQGLARYIGASSMKTWEFVELQNVAKANGWHQFISMQSHYSLLYREDERELNDYCKKNSIGLIPWSPNGGGVLCRPFDSEKTKQFLDNKQWSSLFGLENVRDADKIIVDRVKELSVKYNASMMQVSLAWCISKGVIPIAGVSKFEQAEELVGIFKVNLTEDDIKYLEEPYHAKDLARVAA
InterPro domains: - IPR036812: NAD(P)-dependent oxidoreductase domain superfamily (homologous_superfamily) [2-330]
- IPR050523: Aldo/Keto Reductase Detoxification and Biosynthesis (family) [3-330]
- IPR023210: NADP-dependent oxidoreductase domain (domain) [15-325]
Interaction partners: - Wh11p
- Glyoxalase 3
- 17-beta-hydroxysteroid dehydrogenase-like protein
- Adh5p
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051703 (biological process involved in intraspecies interaction between organisms), GO:0009987 (cellular process), GO:0044010 (single-species biofilm formation), GO:0098743 (cell aggregation), GO:0098630 (aggregation of unicellular organisms), GO:0090609 (single-species submerged biofilm formation), GO:0042710 (biofilm formation), GO:0044011 (single-species biofilm formation on inanimate substrate), GO:0090605 (submerged biofilm formation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005618 (cell wall), GO:0009277 (fungal-type cell wall)
Protein: Mitochondrial import inner membrane translocase subunit Tim8 B (Deafness dystonia protein 2 homolog) (P62077)
Organism: Mus musculus (Mouse)
Function: Probable mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
Subcellular location: Mitochondrion inner membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Intermembrane side {ECO:0000250}.
Sequence: MAELGEADEAELQRLVAAEQQKAQFTAQVHHFMELCWDKCVEKPGSRLDSRTENCLSSCVDRFIDTTLAITGRFAQIVQKGGQ
InterPro domains: - IPR035427: Tim10-like domain superfamily (homologous_superfamily) [1-83]
- IPR004217: Tim10-like (domain) [16-76]
Interaction partners: - Mitochondrial import inner membrane translocase subunit Tim13
- Mitochondrial import inner membrane translocase subunit Tim10
- Large ribosomal subunit protein mL53
- NADH dehydrogenase iron-sulfur protein 5
- Mitochondrial import receptor subunit TOM7 homolog
- Mitochondrial import inner membrane translocase subunit Tim9
- Small ribosomal subunit protein mS33
- NADH dehydrogenase 1 subunit C1, mitochondrial
- NADH dehydrogenase 1 alpha subcomplex subunit 5
- Mitochondrial import inner membrane translocase subunit Tim10 B
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0007005 (mitochondrion organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: methylcrotonoyl-CoA carboxylase (EC 6.4.1.4) (3-methylcrotonyl-CoA carboxylase 2) (3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta) (Q385A6)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MKSFCRLGKVCGCSVSVVFSHRVFALGPRRDYSTSEVPLGSSQVPKGDPRKEQKGGNMSEVYLFHPAQYESAPATTRPNVLHYPAESTNPEFKANTERMKALTAELRRRVQVIVDGDSEADKRARDRHISRGKLLVHQRIEKLVDPMSPFLELSQLAGGDLYPGEACHRGGILTGIGVVHGMRVMIVANDATVKGGTYYPITVKKHLRAQRIAEENRLPCIYLVDSGGANLGMQGDVFPDEQHFGRIFFNQANMSAKGIAQIATVMGSCTAGGAYVPAMSDESIIVKGNGTIFLGGPPLVFAATGEEVTPEELGGADVHCRASGVTDYFATDDLHALYLTRRIVANLNRNDCERPCRGREFTPPLYDPSEIGGFIPDMGADVVKGFDVRAVIARLVDGSEFDEFKKLYGDTLVCGFARFEGMLVGIVANNGILYSESALKGAHFVELCSHRNIPLLFLQNITGFMVGKTYEEGGIAKNGAKLVTAVSTTHVPKITIIIGGSYGAGNYGMCGRAFGPRFLFMWPNARISVMGGNQAATVLALTNSKLRENEVQDFKAKVRSKYEYEGSCYYSTARLWDDGVIAPEDTRAVVVQALLSTLSAPCGETKFGVFRM
InterPro domains: - IPR045190: Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like (family) [74-612]
- IPR011762: Acetyl-coenzyme A carboxyltransferase, N-terminal (domain) [99-359]
- IPR029045: ClpP/crotonase-like domain superfamily (homologous_superfamily) [119-594]
- IPR034733: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (domain) [128-597]
- IPR011763: Acetyl-coenzyme A carboxyltransferase, C-terminal (domain) [375-600]
Interaction partners: - 3-methylcrotonyl-CoA carboxylase, putative
- Biotin--acetyl-CoA-carboxylase ligase, putative
- Isovaleryl-coA dehydrogenase, putative
- Probable enoyl-CoA hydratase, mitochondrial
- Methylglutaconyl-CoA hydratase, mitochondrial, putative
- hydroxymethylglutaryl-CoA lyase
- Citrate synthase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016874 (ligase activity), GO:0016885 (ligase activity, forming carbon-carbon bonds), GO:0016421 (CoA carboxylase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006520 (amino acid metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006082 (organic acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:1901605 (alpha-amino acid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0009064 (glutamine family amino acid metabolic process), GO:0006560 (proline metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Cecropin-P1 (P14661)
Organism: Ascaris suum (Pig roundworm) (Ascaris lumbricoides)
Function: Has antibacterial activity against several Gram-positive and Gram-negative bacteria. Is weakly active against yeasts. Acts by a nonpore mechanism.
Subcellular location: Secreted {ECO:0000269|PubMed:2512577}.
Sequence: MFLIYLFVQTAESSWLSKTAKKLENSAKKRISEGIAIAIQGGPRRRRFVAEQDAIHSRVSREVPTLSDSV
InterPro domains: - IPR000875: Cecropin-like (family) [21-50]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0002376 (immune system process), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051234 (establishment of localization), GO:0006950 (response to stress), GO:0002440 (production of molecular mediator of immune response), GO:0071704 (organic substance metabolic process), GO:0009607 (response to biotic stimulus), GO:0006955 (immune response), GO:0051707 (response to other organism), GO:0006952 (defense response), GO:0043207 (response to external biotic stimulus), GO:0043170 (macromolecule metabolic process), GO:0006810 (transport), GO:0006959 (humoral immune response), GO:0098542 (defense response to other organism), GO:0019730 (antimicrobial humoral response), GO:0071702 (organic substance transport), GO:0046903 (secretion), GO:0071705 (nitrogen compound transport), GO:0010467 (gene expression), GO:0061844 (antimicrobial humoral immune response mediated by antimicrobial peptide), GO:0042886 (amide transport), GO:0015833 (peptide transport), GO:0002790 (peptide secretion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: NUDIX hydrolase, conserved (Q381M2)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MRKQLFFTLARPCVAVGRRFISGDNKSIDSSAFISDDDALRGELASALDTEGHALPFDVHLQQPHSSGDGTAGDTSTIQLEKLSHPPARFDLLTNSFVYKWQTKAALARKVSGPMREWAAELKYRTGVHIELEPTYPERLSENAVKGSGSDEGDGTQWGAYETADDVDITVYLFGSERGIFNCHKLMEAAIQQDPVYVRLGIFRRLANSSEVEWLMLRRINRELRPPDIPPISLKLPGKWTLLYERYKEAAIRTLWEETGITVDASNVYPTGHLYQTVPQYYWRVPVRYFVAEVPSDIRVEGPQVVPLQYMRNWDARLLRQSPDPIDRAWAQLADPATGCAWMKASMIDQLQKPLRGDNYMAIRYTPPPYSNLQEVVGLGDGSITPSTGNGEDAS
InterPro domains: - IPR000086: NUDIX hydrolase domain (domain) [245-316]
- IPR015797: NUDIX hydrolase-like domain superfamily (homologous_superfamily) [209-317]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016462 (pyrophosphatase activity), GO:0047429 (nucleoside triphosphate diphosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0019637 (organophosphate metabolic process), GO:0006793 (phosphorus metabolic process), GO:0006753 (nucleoside phosphate metabolic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0009117 (nucleotide metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0020023 (kinetoplast), GO:0005737 (cytoplasm), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Uridine phosphorylase 2 isoform 4 (A0A0S2Z639)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MASVIPASNRSMRSDRNTYVGKRFVHVKNPYLDLMDEDILYHLDLGTKTHNLPAMFGDVKLLWSV
InterPro domains: - IPR035994: Nucleoside phosphorylase superfamily (homologous_superfamily) [8-65]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0007005 (mitochondrion organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Variant surface glycoprotein (VSG, atypical), putative (Q38CQ1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Sequence: MALLQSSGIRTAILIAVCGALSNRSAAHTSKHPLLATEIKPLCGLSGQLKTTALYVKQKLNQQATYTDSITQLARKLVVYSKTRTDDDDARIALALATEAQKLQEAATRKLLTMASKGTVLAVQAGLAAGIIDDFIALVAGVTPGGTTNNNCIINKDALSGTATFTTIAEQLPGCETTEIVTTEPPAKPILRGQDFTGFNNIKTLGNAATYSQTCCKLLQHASDADLTGAGYTGNKLLVAGGAIHVTSNNIQIAKLTNLSSAADQSVFENTQKKLKDFDVHKADDPATTHVALYTAALTSEAVKAATDIKLQKKRRTNQEINADSALESKVKGIIGSDADSFKNTYLDKVNKETIKLPKEWELELSYNKLENLETDAQYETILLYLSKVSQNNREQACTAVRQEQKQQETDETCEKKGTEDNYKDGCKWDGEGDNKKCVKDLDYKPKQVEEKDDGIKEEKCAGKQQEDCKSMDCKWKGENYKYSSFLVDKKMALSMDTAFKGLVEFSNFKNLFSIL
InterPro domains: - IPR019609: Trypanosome variant surface glycoprotein, C-terminal (domain) [414-503]
- IPR027446: Variant surface glycoprotein C-terminal domain superfamily (homologous_superfamily) [397-455]
- IPR001812: Trypanosome variant surface glycoprotein, A-type, N-terminal domain (domain) [16-386]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0046812 (host cell surface binding), GO:0046789 (host cell surface receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response), GO:0042783 (evasion of host immune response), GO:0020033 (antigenic variation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide-sensitive factor attachment protein alpha) (P54921)
Organism: Rattus norvegicus (Rat)
Function: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Together with GNA12 promotes CDH5 localization to plasma membrane.
Subcellular location: Cell membrane {ECO:0000250|UniProtKB:P54920}; Peripheral membrane protein {ECO:0000250|UniProtKB:P54920}.
Sequence: MDTSGKQAEAMALLAEAERKVKNSQSFFSGLFGGSSKIEEACEIYARAANMFKMAKNWSAAGNAFCQAAQLHLQLQSKHDAATCFVDAGNAFKKADPQEAINCLMRAIEIYTDMGRFTIAAKHHISIAEIYETELVDVEKAIAHYEQSADYYKGEESNSSANKCLLKVAGYAAQLEQYQKAIDIYEQVGTSAMDSPLLKYSAKDYFFKAALCHFCIDMLNAKLAVQKYEELFPAFSDSRECKLMKKLLEAHEEQNVDSYTESVKEYDSISRLDQWLTTMLLRIKKTIQGDEEDLR
InterPro domains: - IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [7-295]
- IPR000744: NSF attachment protein (family) [1-288]
Interaction partners: - Vesicle-associated membrane protein 2
- Syntaxin-1A
- Syntaxin-5
- Synaptosomal-associated protein 23
- Multifunctional fusion protein
- Vesicle-associated membrane protein 3
- Vesicle-associated membrane protein 7
- Vesicle-associated membrane protein 8
- BET1 homolog
- Vesicle-fusing ATPase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0000149 (SNARE binding), GO:0019905 (syntaxin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0071840 (cellular component organization or biogenesis), GO:0065009 (regulation of molecular function), GO:0032879 (regulation of localization), GO:0050794 (regulation of cellular process), GO:0016043 (cellular component organization), GO:0060627 (regulation of vesicle-mediated transport), GO:0051049 (regulation of transport), GO:0051128 (regulation of cellular component organization), GO:0043462 (regulation of ATP-dependent activity), GO:0030100 (regulation of endocytosis), GO:0043933 (protein-containing complex organization), GO:0022411 (cellular component disassembly), GO:0048259 (regulation of receptor-mediated endocytosis), GO:0032984 (protein-containing complex disassembly), GO:0002090 (regulation of receptor internalization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0048786 (presynaptic active zone), GO:0098793 (presynapse), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0098794 (postsynapse), GO:0042734 (presynaptic membrane), GO:0048787 (presynaptic active zone membrane), GO:0045202 (synapse), GO:0098590 (plasma membrane region), GO:0005886 (plasma membrane), GO:0097060 (synaptic membrane)
Protein: NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (F1QCG4)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Sequence: MDLHRAAMLNFVDCNVDEMDTKNRKTQQCEDRVDSGVDSLKEEEYETREISEEMEKLTIASLKETICEPWAKVVTEDGDTYLHLAIIHEAEDYAVQIIKQCQNDPYLNRQNNQRQTALHLAVVTEQPQMVERLLKAGCDPQLVDQSGNTALHLACKQGSLACFSVLTQIQTQHLRSILTFPNYSGHTCLHIAAINNYLSMVESLVQLGADVDAKEQCSGRTSLHLAVDLQNLDLVHTLIALGADANSLTYGGYTAYHLTFGRHNSEIQRQLYSRTALKFTVMPESESEESEDELMSEDDCIYDDIRLCGR
InterPro domains: - IPR051070: NF-kappa-B Inhibitor (family) [21-293]
- IPR036770: Ankyrin repeat-containing domain superfamily (homologous_superfamily) [72-303]
- IPR002110: Ankyrin repeat (repeat) [77-250]
Interaction partners: - S-phase kinase-associated protein 1
- Inhibitor of nuclear factor kappa B kinase subunit beta.
- Nuclear factor NF-kappa-B p105 subunit isoform X1
- Transcription factor p65
- Inhibitor of nuclear factor kappa-B kinase subunit alpha
- Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
- Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon.
- NF-kappa-B inhibitor alpha
- F-box only protein 22
- Ubiquitin-ribosomal protein eS31 fusion protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0051641 (cellular localization), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0051234 (establishment of localization), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0046907 (intracellular transport), GO:0048731 (system development), GO:0006810 (transport), GO:0048513 (animal organ development), GO:0051649 (establishment of localization in cell), GO:0009790 (embryo development), GO:1904888 (cranial skeletal system development), GO:0048703 (embryonic viscerocranium morphogenesis), GO:0048705 (skeletal system morphogenesis), GO:0048568 (embryonic organ development), GO:0001501 (skeletal system development), GO:0048562 (embryonic organ morphogenesis), GO:0048701 (embryonic cranial skeleton morphogenesis), GO:0051169 (nuclear transport), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development), GO:0048704 (embryonic skeletal system morphogenesis), GO:0048706 (embryonic skeletal system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)