Protein: Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 (Proteasome 26S subunit, non-ATPase 14) (Q17QP9)
Organism: Bos taurus (Bovine)
Function: Not known
Sequence: MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK
InterPro domains: - IPR000555: JAB1/MPN/MOV34 metalloenzyme domain (domain) [27-165]
- IPR050242: JAMM/MPN+ metalloenzymes, peptidase M67A (family) [26-306]
- IPR037518: MPN domain (domain) [31-166]
- IPR056263: 26S proteasome regulatory subunit RPN11, C-terminal domain (domain) [228-307]
Interaction partners: - 26S proteasome regulatory subunit 6B
- 26S proteasome regulatory subunit 7
- Proteasome subunit alpha type-5
- Proteasome 26S subunit, ATPase 3
- Proteasome subunit alpha type-3
- 26S proteasome non-ATPase regulatory subunit 6
- 26S proteasome non-ATPase regulatory subunit 4
- Proteasome 26S subunit, ATPase 1
- 26S proteasome non-ATPase regulatory subunit 12
- 26S proteasome non-ATPase regulatory subunit 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0008233 (peptidase activity), GO:0008237 (metallopeptidase activity), GO:0019783 (ubiquitin-like protein peptidase activity), GO:0140492 (metal-dependent deubiquitinase activity), GO:0101005 (deubiquitinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0044085 (cellular component biogenesis), GO:1901564 (organonitrogen compound metabolic process), GO:0044248 (cellular catabolic process), GO:0019538 (protein metabolic process), GO:0016043 (cellular component organization), GO:1901575 (organic substance catabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:0009057 (macromolecule catabolic process), GO:0043412 (macromolecule modification), GO:1901565 (organonitrogen compound catabolic process), GO:0006508 (proteolysis), GO:0044265 (cellular macromolecule catabolic process), GO:0030163 (protein catabolic process), GO:0043933 (protein-containing complex organization), GO:0022607 (cellular component assembly), GO:0070646 (protein modification by small protein removal), GO:0065003 (protein-containing complex assembly), GO:0070647 (protein modification by small protein conjugation or removal), GO:0043632 (modification-dependent macromolecule catabolic process), GO:0010498 (proteasomal protein catabolic process), GO:0051603 (proteolysis involved in protein catabolic process), GO:0016579 (protein deubiquitination), GO:0043248 (proteasome assembly), GO:0019941 (modification-dependent protein catabolic process), GO:0043161 (proteasome-mediated ubiquitin-dependent protein catabolic process), GO:0006511 (ubiquitin-dependent protein catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0022624 (proteasome accessory complex), GO:1902494 (catalytic complex), GO:0005622 (intracellular anatomical structure), GO:0005838 (proteasome regulatory particle), GO:0140535 (intracellular protein-containing complex), GO:1905368 (peptidase complex), GO:0000502 (proteasome complex), GO:1905369 (endopeptidase complex)