Protein: Gibberellin 3-beta-dioxygenase 4 (EC 1.14.11.15) (GA 3-oxidase 4) (AtGA3ox4) (Gibberellin 3 beta-hydroxylase 4) (Q9C971)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Converts the inactive gibberellin (GA) precursors GA9 and GA20 in the bioactives gibberellins GA4 and GA1. Involved in the production of bioactive GA for reproductive development.
Sequence: MPSLAEEICIGNLGSLQTLPESFTWKLTAADSLLRPSSAVSFDAVEESIPVIDLSNPDVTTLIGDASKTWGAFQIANHGISQKLLDDIESLSKTLFDMPSERKLEAASSDKGVSGYGEPRISPFFEKKMWSEGFTIADDSYRNHFNTLWPHDHTKYCGIIQEYVDEMEKLASRLLYCILGSLGVTVEDIEWAHKLEKSGSKVGRGAIRLNHYPVCPEPERAMGLAAHTDSTILTILHQSNTGGLQVFREESGWVTVEPAPGVLVVNIGDLFHILSNGKIPSVVHRAKVNHTRSRISIAYLWGGPAGDVQIAPISKLTGPAEPSLYRSITWKEYLQIKYEVFDKAMDAIRVVNPTN
InterPro domains: - IPR026992: Non-haem dioxygenase, N-terminal domain (domain) [49-150]
- IPR050231: Iron/ascorbate-dependent oxidoreductase (family) [49-337]
- IPR005123: Oxoglutarate/iron-dependent dioxygenase domain (domain) [203-303]
- IPR044861: Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain (domain) [206-300]
- IPR027443: Isopenicillin N synthase-like superfamily (homologous_superfamily) [13-343]
Interaction partners: - Gibberellin 20 oxidase 3
- Gibberellin 20 oxidase 1
- Gibberellin 20 oxidase 4
- Gibberellin 20 oxidase 2
- Gibberellin 2-beta-dioxygenase 6
- Gibberellin 2-beta-dioxygenase 4
- Gibberellin 2-beta-dioxygenase 3
- Gibberellin 2-beta-dioxygenase 2
- Gibberellin 2-beta-dioxygenase 1
- Gibberellin 2-beta-dioxygenase 7
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0051213 (dioxygenase activity), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen), GO:0016706 (2-oxoglutarate-dependent dioxygenase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009628 (response to abiotic stimulus), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0009314 (response to radiation), GO:0006082 (organic acid metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0009416 (response to light stimulus), GO:0006720 (isoprenoid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0016053 (organic acid biosynthetic process), GO:0008299 (isoprenoid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0009639 (response to red or far red light), GO:0046394 (carboxylic acid biosynthetic process), GO:0006721 (terpenoid metabolic process), GO:0016114 (terpenoid biosynthetic process), GO:0016101 (diterpenoid metabolic process), GO:0016102 (diterpenoid biosynthetic process), GO:0010114 (response to red light), GO:0009685 (gibberellin metabolic process), GO:0009686 (gibberellin biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)