Protein: ATP-dependent RNA helicase (D6WYU0)
Organism: Tribolium castaneum (Red flour beetle)
Function: RNA helicase
Sequence: MGKSWAELGVKLHKEVQNAVKTLNFPTMTPIQAAAIPQLLNKKDVVAEAVTGSGKTLAFLIPLLQILKQRDKWKKAEIGALIISPTRELATQINQVLNQLLESISGITSLLLVGGNSVEEDLNNLKCNGGNIIICTPGRFEDLLSRKSDFNLTLALKNLEILILDEADRLLDYGFRKSLDVILSYLPKQRRTGLFSATQTKQLQDLIRAGLRNPVLVSVSVKAEHSTPEKLENYYVVANNNNKLAALFAFLQSRDVQKAMLFLPTCAVVDFWSETFPCVFNDLPVLAIHGKMKEKRKKIIERFKNSPKGLLLCTDVLARGIDIPEVDWVLQWDPPASASAFVHRVGRTARQGRQGSSLLFLLDTEESYVPFIEKNQRVKLDQLSDVSDTKMCENLRDILQNLQKTDRDLMEKAKRAFVSHVRAYSKYECSLLLRIKEFPFGQVATSYGLLQLPKMPELKKYDSVGFEPLEIDLNTIPYKDKQREKARLQKLEIYQNTGSWPGKPKIVKKPSEPWSLTKQKKNEKKEKRLKRKRAKEKKRKSGLSEEDLAELAQDVALIKKCKKRKISENELDKSFGLA
InterPro domains: - IPR056330: ATP-dependent rRNA helicase SPB4-like, C-terminal tail (domain) [478-574]
- IPR011545: DEAD/DEAH-box helicase domain (domain) [29-206]
- IPR001650: Helicase, C-terminal domain-like (domain) [243-403]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [24-234]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [2-465]
- IPR000629: ATP-dependent RNA helicase DEAD-box, conserved site (conserved_site) [163-171]
- IPR025313: ATP-dependent rRNA helicase SPB4-like, C-terminal extension (domain) [394-457]
Interaction partners: - Putative rRNA methyltransferase
- Ribosome biogenesis protein WDR12 homolog
- Ribosome biogenesis protein BOP1 homolog
- Nucleolar GTP-binding protein 1
- Ribosome biogenesis protein NSA2 homolog
- NOC3-like protein
- MKI67 FHA domain-interacting nucleolar phosphoprotein-like
- Guanine nucleotide-binding protein-like 3 homolog
- Ribosomal L1 domain-containing protein CG13096-like Protein
- Putative rRNA-processing protein EBP2 homolog-like Protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0097159 (organic cyclic compound binding), GO:0004386 (helicase activity), GO:0008186 (ATP-dependent activity, acting on RNA), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0140098 (catalytic activity, acting on RNA), GO:0003724 (RNA helicase activity), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009791 (post-embryonic development), GO:0002164 (larval development), GO:0002119 (nematode larval development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)