wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: RNA helicase (EC 3.6.4.13) (D7F7W9)
Organism: Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Sequence: TDFGLYEYQEEVVQRALRGENIIIWLPTGGGKTRAAVYVAKKHLENNPGAKVAVLVNKVHLVDQHYNNEFNPYLGSDYSLVSISGDCDQKDFFGCEVKNFDLVICTAQILENALTNQEEGKHVELSQFTLLIIDECHHTHKEGVYNKIMARYVAQKLKGERRLPQILGLTASPGTGGAKSIKGAVEHVLQICANLDSVIVSSKVYAPELKKKVPRPRKRFDIVDRRPQDPFGDHLKFMMQFIHDFMALGPEFPVREFGTQEYEADVVILEKKGVTDRNRLLAQCALHLRQYNDALLINDTVRMVDAFRVLESYYSTKSSTAMDGTDFFLLGLYQENEVELRKLSGDARFENPKMGKLQNTLLEQFVQGGHSRGILFSKTRKSICCLYDWVSNNPALQRAGIRAAILTGAGNGINYMTQNEQKDTIRNFRLGSLNLLISTSVAEEGLDIPECNLVVRYGLLTNEIAQQQASGRARASDSVYSVVAQAGGREVRRELLNECLEDLTGRAIGEVQRMEPRDFRMKITDLQTEALLTRQLAEQLKLKKRSRFNAATVQLSCRGCFLPVALGHDIKVIENAHHVNINPDFERYYKTGGQPALKTFEDWEPGRVISCAACGRQWGMEMIYKNIALLPILAIENFAMETPEGRKLAKKWKNVEFTVEEFNFSTYCHNKFPNMLD
InterPro domains: - IPR041204: RIG-I-like receptor, C-terminal (domain) [218-344]
- IPR006935: Helicase/UvrB, N-terminal (domain) [4-173]
- IPR038557: RIG-I-like receptor, C-terminal domain superfamily (homologous_superfamily) [542-677]
- IPR051363: RIG-I-like Receptor (RLR) Helicase (family) [5-665]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [7-527]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [1-198]
- IPR001650: Helicase, C-terminal domain-like (domain) [361-527]
- IPR021673: RIG-I-like receptor, C-terminal regulatory domain (domain) [543-669]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003725 (double-stranded RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0002376 (immune system process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0051707 (response to other organism), GO:0006955 (immune response), GO:0009607 (response to biotic stimulus), GO:0006952 (defense response), GO:0043207 (response to external biotic stimulus), GO:1901698 (response to nitrogen compound), GO:0010033 (response to organic substance), GO:0045087 (innate immune response), GO:0098542 (defense response to other organism), GO:0043331 (response to dsRNA), GO:0014070 (response to organic cyclic compound), GO:0043330 (response to exogenous dsRNA)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure), GO:0048471 (perinuclear region of cytoplasm)
Protein: Chromosome 17 open reading frame 49 (F8W1H0)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MQLHPVADSSPAGAKWTETEIEMLRAAVKRFGDDLNHISCVIKERTVAQIKATVKRKVYEDSGIPLPAESPKKGPKKVASGVLSPPPAAPPPSSSSVPEAGGPPIKKQKADVTLSALNDSDANSDVVDIEGLGETPPAKKLNFDQDSLTLDSGLLMTSADPPLLSC
InterPro domains: - IPR009057: Homedomain-like superfamily (homologous_superfamily) [6-52]
- IPR001005: SANT/Myb domain (domain) [15-51]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0048523 (negative regulation of cellular process), GO:0009892 (negative regulation of metabolic process), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0009890 (negative regulation of biosynthetic process), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0010558 (negative regulation of macromolecule biosynthetic process), GO:0031327 (negative regulation of cellular biosynthetic process), GO:0051252 (regulation of RNA metabolic process), GO:0051253 (negative regulation of RNA metabolic process), GO:0045934 (negative regulation of nucleobase-containing compound metabolic process), GO:0010468 (regulation of gene expression), GO:2001141 (regulation of RNA biosynthetic process), GO:1902679 (negative regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:0006357 (regulation of transcription by RNA polymerase II), GO:1903507 (negative regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0045892 (negative regulation of DNA-templated transcription), GO:0000122 (negative regulation of transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Ergic53, isoform A (Ergic53, isoform B) (LD43551p) (Rhea) (Q9V3A8)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
Sequence: MRPTFLAILCFLAWNPSSEATGNLSPGAVGVHRRFEYKYSFKPPYLAQKDGTVPFWEYGGNAIASSESVRVAPSLRSQKGAIWTKSQTNFDWWDVEIVFRVTGRGRIGADGLAFWYTTEKGDYNGPVFGSSDRWNGLAIMFDSFDNDNKHNNPYISAVLNDGTKLYDHAEDGTTQLLSGCLRDFRNKPFPTRARIEYYNNVLTVMIHNGMSNNNDDYELCLRADGVNLPKNGYFGISAATGGLADDHDVFHFLTTSLHAAGQVQEQPKVENQEKLTQEYKEYQDKLEKQKQEYKKDHPDEHKDEEDWEEFYESENQRELRQIWQGQSQIADHLRELSRKVDEIIGRQETTLSLVSRNAGQALPPPAAGGVPQQQLPVGAVSRSDVDLLLTNQNMLLSSIREIRQLVGDINVRTDNIQTNQKHAPTAQIQSTGYDVQTLIAEMRDGMNQVKQGITHVGQRLAAPQGAAQVANCPTGNCVGVTLFLSVTVVQLLLVFIYNVFKNRSEAQAKKFY
InterPro domains: - IPR005052: Legume-like lectin (domain) [33-258]
- IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [32-258]
- IPR051136: Intracellular Lectin and Glycoprotein Transporter (family) [5-505]
Interaction partners: - Uncharacterized protein, isoform A
- Protein transport protein SEC23
- EF-hand domain-containing protein
- Protein transport protein Sec31A
- Secretory 22, isoform B
- Protein SEC13 homolog
- Transport and Golgi organization protein 1
- FI09914p
- Secretory 16, isoform I
- RE50040p
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:0030246 (carbohydrate binding), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0043169 (cation binding), GO:0048029 (monosaccharide binding), GO:0051082 (unfolded protein binding), GO:0005537 (mannose binding), GO:0046872 (metal ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0046907 (intracellular transport), GO:0051649 (establishment of localization in cell), GO:0006810 (transport), GO:0006888 (endoplasmic reticulum to Golgi vesicle-mediated transport), GO:0016192 (vesicle-mediated transport), GO:0048193 (Golgi vesicle transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0005783 (endoplasmic reticulum), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005793 (endoplasmic reticulum-Golgi intermediate compartment), GO:0030135 (coated vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0030134 (COPII-coated ER to Golgi transport vesicle), GO:0097708 (intracellular vesicle)
Protein: Protein LNK1 (Night light-inducible and clock-regulated 1) (A8MQN2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcriptional coactivator necessary for expression of the clock genes PRR5 and TOC1. Antagonizes REV8 function in the regulation of anthocyanin accumulation. Involved in red light input to the clock. Activates clock-controlled genes with afternoon peak. Mediates light inhibition of hypocotyl elongation.
Subcellular location: Nucleus {ECO:0000269|PubMed:25012192}.
Sequence: MSDLYIHELGDYLSDEFHGNDDGIVPDSAYEDGGQFPILVSNRKKRRNDDMGSGTNHLKSNTFIKREANMLGKNPWPEKDSGGSSVSRDTGTGKDVQDMTLEDTNTSDHGFNGGHVDVVENFSTGDPMLCDTSAATNDGVYNYSLNSIPDAENDLSFFDNGDKEKNDLFYGWGDIGNFEDVDNMLRSCDSTFGLDSLNNEGDLGWFSSAQPNEETAGAMTDDLKPDKMLENQRTAMLQVEDFLNNSEPNHAVEDEYGYTIEDDSAQGKSSQNVFDTSLQKKDILMLDVEANLEKKQTDHLHHLDGKSDGFSENSFTLQHSGISREIMDTNQYYPPSAFQQRDVPYSHFNCEQPSVQVSACESKSGIKSENKPSPSSASNESYTSNHAQSIESLQGPTVDDRFRKVFETRANLLPGQDMPPSFAANTKKSSKTDSMVFPDAAPIQKIGLENDHRKAATELETSNMQGSSCVSSVVDDISLEATSFRQLQQVIEQLDVRTKLCIRDSLYRLAKSAEQRHHGGNRPEKGAGSHLVTGEADKYAGFMDIETDTNPIDRSIAHLLFHRPSDSSLSSDNNVLSYKSHPMIPQPNSSPSLRIEKQEETTELRPEAEVVTSDNN
InterPro domains: - IPR039928: LNK family (family) [8-592]
Interaction partners: - Protein REVEILLE 8
- Protein LHY
- Protein CCA1
- Protein LNK3
- Two-component response regulator-like APRR9
- Protein LNK4
- Protein REVEILLE 4
- Protein REVEILLE 6
- Two-component response regulator-like APRR7
- Two-component response regulator-like APRR5
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0005488 (binding), GO:0005515 (protein binding), GO:0003712 (transcription coregulator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048511 (rhythmic process), GO:0009605 (response to external stimulus), GO:0019222 (regulation of metabolic process), GO:0042752 (regulation of circadian rhythm), GO:0007623 (circadian rhythm), GO:0009649 (entrainment of circadian clock), GO:0060255 (regulation of macromolecule metabolic process), GO:0032922 (circadian regulation of gene expression), GO:0010468 (regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: histone acetyltransferase (EC 2.3.1.48) (Q5ACY2)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MSVTTTTNIIKASPKRKTKTDTKDQDNSYYGQLNKRNINKVTFGKYEFPTWYGNAAYFYPHDLSHSSLGYEYANKVASEGSIARKIHKKDIFDENLHEFWLDHLFVCEYCFKYTSNETILNQHVTACTYNRKRPSKGKLLYHDQANGYIIREVRGFQDPLFCQNLCLFGKLFLDDKSVYYNIDHFDFYIVFGKDDSSYIPMGFFSKEVLSYDNDNNLACICVFPPFQRRHLGSLLIEFSYQLAAVTPGQLKSSGPEFPLSPYGKVTYLRFWSKRLATKIHELQGSFTLSHLSKETGFRKEDILLTLEYMQILVTDDLGNVTLSLERLENWCSQNKVVPGVDINILNSECLIL
InterPro domains: - IPR013087: Zinc finger C2H2-type (domain) [105-134]
- IPR016181: Acyl-CoA N-acyltransferase (homologous_superfamily) [36-344]
- IPR002717: Histone acetyltransferase domain, MYST-type (domain) [33-332]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [259-325]
- IPR050603: MYST family histone acetyltransferases (family) [21-335]
Interaction partners: - Histone H4
- Histone acetyltransferase
- Chromatin modification-related protein EAF6
- Chromatin modification-related protein EAF3
- Enhancer of polycomb-like protein 1
- RuvB-like helicase 1
- SWR1-complex protein 4
- Histone acetyltransferase GCN5
- NAD-dependent histone deacetylase SIR2
- Actin-related protein 4
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0061733 (peptide-lysine-N-acetyltransferase activity), GO:0004402 (histone acetyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016407 (acetyltransferase activity), GO:0010485 (histone H4 acetyltransferase activity), GO:0016410 (N-acyltransferase activity), GO:0008080 (N-acetyltransferase activity), GO:0034212 (peptide N-acetyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0043543 (protein acylation), GO:0018193 (peptidyl-amino acid modification), GO:0016570 (histone modification), GO:0006473 (protein acetylation), GO:0018205 (peptidyl-lysine modification), GO:0016573 (histone acetylation), GO:0018394 (peptidyl-lysine acetylation), GO:0006475 (internal protein amino acid acetylation), GO:0043967 (histone H4 acetylation), GO:0018393 (internal peptidyl-lysine acetylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Transcription factor YY1 (Transcriptional repressor protein YY1a) (YY1 transcription factor a) (Yy1a protein) (Q7T1S3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MASGETLYIEADGSEMPAEIVELHEIEVETIETTVVGGDDDEHQPMIALQPLVTDDPNHVNHQEVILVQTREEVVGCDDSDLHADDSFEDQILIPVPVPVAEEEYIEQTLVTVSGKNPSGRMKKGGGSGKRVVKKSFLNSAEASGRKWEQKQVQIKTLEGEFSVTMWASDDKKDVDHETVVEEQIIGENSPPDYSEYMTGKKLPPGGIPGIDLSDPKQLAEFARMKPRKIKEDDSPRTIACPHKGCTKMFRDNSAMRKHLHTHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPFQCTFEGCGKRFSLDFNLRTHVRIHTGDRPYVCPFDGCNKKFAQSTNLKSHILTHAKAKNNQ
InterPro domains: - IPR017114: C2H2-type Zinc finger protein, YY1-like (family) [1-357]
- IPR013087: Zinc finger C2H2-type (domain) [239-355]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [238-354]
Interaction partners: - Histone deacetylase 1
- Histone-lysine N-methyltransferase EZH2
- RING1 and YY1-binding protein A
- Lethal
- RuvB-like 1
- INO80 complex ATPase subunit.
- Actin-related protein 8
- Actin-related protein 5
- INO80 complex subunit C
- Nuclear factor-related to kappaB-binding protein.
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0006325 (chromatin organization), GO:0043933 (protein-containing complex organization), GO:0006996 (organelle organization), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly), GO:0071824 (protein-DNA complex subunit organization), GO:0006338 (chromatin remodeling), GO:0051276 (chromosome organization), GO:0065004 (protein-DNA complex assembly), GO:0034508 (centromere complex assembly), GO:0034080 (CENP-A containing chromatin assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Single-pass membrane and coiled-coil domain-containing protein 3 (A2RU48)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Sequence: MAQSDFLYPENPKRREEVNRLHQQLLDCLSDSFDVTNKLTEVLNMHLGCRLASIEMKRDGTIKENCDLIIQAIMKIQKELQKVDEALKDKLEPTLYRKLQDIKEKETDKIAIVQKVISVILGEATSAASAVAVKLVGSNVTTGIINKLVTVLAQIGASLLGSIGVAVLGLGIDMIVRAILGAVEKTQLQAAIKSYEKHLVEFKSASEKYNHAITEVINTVKHQMK
InterPro domains: - IPR027895: Protein of unknown function DUF4533 (family) [14-221]
- IPR040004: Single-pass membrane and coiled-coil domain-containing protein 3 (family) [1-225]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0050794 (regulation of cellular process), GO:0048731 (system development), GO:0042127 (regulation of cell population proliferation), GO:0007399 (nervous system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005829 (cytosol), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Nuclear export mediator factor (A0A8I6A9M7)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Sequence: MVIAPDWWEFFRIPILLPKESLLGMRVNNVYDVDNKTYLIRLQKPDFKATLLLESGIRIHTTEFEWPKNMMPSSFAMKCRKHLKSRRLVSAKQLGVDRIVDFQFGSDEAAYHLIIELYDRGNIVLTDYEYLILNILRFRTDEADDVKFAVRERYPIDHARAAEPLLTLERLTEVIARAPRGELLKRVLNPLLPYGPALIEHCLIENGFSGNVKVDEKLESKDIEKILVCVQRAEDYLEKTANFNGKGYIIQKREVKPSLDANKPAEDILTYEEFHPFLFSQHLQCPYIEFESFDKAVDEFYSKIEGQKIDLKALQQEKQALKKLDNVRKDHENRLEALQQAQEIDKLKGELIEMNLQIVDRAIQVVRSALANQIDWTEIGVIVKEAQAQGDPVASAIKELKLQTNHITMLLRNPYLLSEEEDGDGDGSIENSDAEAPKGKKKKQKNKQLQKPQKNKPLLVDVDLSLSAYANAKKYYDHKRYAAKKTQRTVEAAEKAFKSAEKKTKQTLKEVQTVTSIQKARKVYWFEKFLWFISSENYLIIGGRDQQQNEIIVKRYLTPGDIYVHADLHGATSCVIKNPTGDPIPPRTLTEAGTMALCYSAAWDARVITSAWWVHHHQVSKTAPTGEYLTTGSFMIRGKKNFLPPSYLMMGFSFLFKVDESCVWRHRGERKVRVQDEDMETLTSCTSELMSEEMEQLEGGDSSEEETEELRGTTEEVELRTQADPEDIAAHSGREELSSEDGEAIKTATKDEEPIGEVREEEEEPFEYPDTTIDLSHLQSQRPLQKLTPREESFNSSDSKSQSRRHLSAKERREMKKKKLPCDSGDLEVIEEKDKEKESAVHSEADQNTSKNVAAGQPMKRGQKSKMKKMKEKYKDQDDEDRELIMKLLASAGSNKEEKGKKGKKGKTKDEPVKKNPQKPRGGQRVLDVVKETPSLQASTPDLQDFAVDEPHDDKEEHDLDQQGNEENLFDSLTGQPHPEDVLMFAIPICAPYTIMTNYKYKVKLTPGVQKKGKAAKTALNSFMHSKEATAREKDLFRSVKDTDLSRNIPGKVKVSAPNLLHVKRK
InterPro domains: - IPR008532: NFACT, RNA-binding domain (domain) [528-638]
- IPR051608: Ribosome Quality Control Complex Subunit NEMF (family) [19-1054]
- IPR021846: NFACT protein, C-terminal (domain) [965-1056]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0046907 (intracellular transport), GO:0045184 (establishment of protein localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0051169 (nuclear transport), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0008104 (protein localization), GO:0015031 (protein transport), GO:0072594 (establishment of protein localization to organelle), GO:0006606 (protein import into nucleus), GO:0006913 (nucleocytoplasmic transport), GO:0033365 (protein localization to organelle), GO:0034504 (protein localization to nucleus), GO:0051170 (import into nucleus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Similar to cain (Q8CGG3)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MIRIAALNASSTIEDDHEGSFKSHKIQTKEAQEAEAFALYHKALDLQKHDRFEESAKAYHELLEARLLREAVSSGDEKEGLKHPGLILKYSTYKNLAQLAAQREDLETAMEFYLEAVMLDSTDVNLWYKIGHVALRLIRLPLARHAFEEGLRCNPDHWPCLDNLITVLYTLSDYTTCLYFICKALEKDCRYSKGLVLKEKIFEEQPCLRKDSLRMFLKCDMSIHDVSVSAAETQAIVDEALGLRKKRQALIVREKEPDLKLVQPIPFFTWKCLGESLLAMYSHLTTCEPPRPSLGKRIDLSDYQDPSQLLASSVVVTPVSVVQPSPICTNPTVAVAEPVLSYTSVTAASFPLHSPSLLDTGTPMGDVSGGDKSKKGVKRKKTVEESGETAKRRSARVRNTKCKKKKKKK
InterPro domains: - IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [5-211]
- IPR033053: Histone transcription regulator 3/CABIN1 (family) [1-408]
- IPR019734: Tetratricopeptide repeat (repeat) [36-157]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)