Protein: Probable inactive serine/threonine-protein kinase gdt1 (Growth-differentiation transition protein 1) (Q54XS3)
Organism: Dictyostelium discoideum (Social amoeba)
Function: Regulates the transition between growth and differentiation.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Sequence: MKKILLSIFFVVFLLIGSECELIDTPPGYYNLKKIDKFQQFSKIQIERNNKTIYSSSFHDLFYPDICEGTIQNIPGSLYFGRSSFPGAQESSNLMITRGTKMKYRVGNGGIPIYKINVLCIEGTLEIPEGISFFNVGALFILPGGVLNSKSSIRFTDLDPYNSKMDPFNFFPGMMVLGGSLSLIGEKKRIFQATRIDDYQLQIEDFKKIGSLTNNIYLGSKVTIYSQQISEGQTCSFSFGASNDKINLTSSSSSSLRGTNCLPISKNDKNIIVHFNCKYLLGGSSESFIDSTSTVGSSIYITGDSQVQIENFTLDSIGKTTNKLYNDTKLIFSNDKPNQVIDIIKGENQRFRNSLYIEFSNSVVIKGCAIIDRVKESRAPLIFVSSNVSLSESLIVSKSGSNLIAQYGTEFIKSKLNHYFLIPPLPQPFGLNSPINFPSPFSMDYGFEGNGIYSLSPNVQSINDTFISQLIALNFNFIGNRSIITGFDNDCYSPCTNTSILFSNLIQYPVDFKINNSTYFYKLNNNNNDNNNNTNNFNLLNINNENNNNDDNNNNNNSQNHYLLNINNNGNSPGRFFTIKDLVASDTVSAYLPNSALVFNNLNATENFSFNGTVSRLDFINSSFNTNLTSTQKFFDETTTTVTNFQNTYIYGSPETTEPPEKVFGSSITPIYYFSKSVLDSLKVETVYPNEPHKMFFNSSVSLSVKLNNMGLKTPIICIFSSNGMESKEVQYNPISTKCSFLYVSEKLGNHNIRVTIKNEYSKDSSYYFIIDFPIITVYGQSLFNAGWQMIDPTSTTIIPTPTPTSTSTSTSTSTPTTTNNNQLVNDNNNKINELDGLKFQGGCIKTLGCQLSSNAKYVGGLPNVTASSTLNSLFSWGITSDVQYDPVIIDLFINKSIATLQVQLFFTFYKPIDQYSSPLSVSIQKNPVLVMEPFAGDQPFSKNLTFVYNNTQSLDFLNISFTSRGDIYLTSLAIFSVSDSLPQIIDPITPTLLPIESVKASKPAILAIVLSIVLGSLALSIITILIVKHRKRLSQFLSKSNKDIEYAQNNEIEIKVLPKITSHSSYPSISILDTISSDSIFNNQIPKNNNRYKFKNQSLNNNNYFNNNNNNNNSNNNNSNNIIYSNCNSNYSNSNSNNNNNNNNSNSNNNSNSNSNININSNSNSNSNSNSNGNNNYQIYSNKLESFKIDEISNDTIPIINSTFPDEFQTLEFQKLAFEILKREKRLDFSFRTTNDILTCCALSDFKDFSNFPLRFNQSIITFGLINGKAKLGETYYDTLSITNDSTIRFTAFLILPMDNHSATFTSDHSSFDLGPGETFSIKFSITLHCTTRFFENFSIQINSNNIKEMYTLLKIKVESESSTRLDFNDIHFQELIEKYSWEILYRGTVGDKNALLKLIKLKTKNCEEAYRELNIISRLKHQNILPLIGCVISKDYLCLAFEYPPLGSLDYIISKKKLKMSITQKIRILIDVAKGCKFLQQSSIIQKTLRARNIFLYDTNENAEVCAKVLDLTSSKTIKGLACNNYIERVDTPINLTREISIIRDPKQNNDFNNSNNSNNNNNNNNNNNNNNNNNSNNSNNSSSLKYNIHSFAVLSYELLIDEILVGDTRKFGQEKPSIGLDKIDPNIKNFIHKCWNPIDGFTFNEILKTLKDFIESLN
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [1365-1658]
- IPR052015: Growth-differentiation transition regulator (family) [2-1660]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [1254-1359]
- IPR001245: Serine-threonine/tyrosine-protein kinase, catalytic domain (domain) [1393-1513]
- IPR000719: Protein kinase domain (domain) [1372-1661]
- IPR026237: Probable serine/threonine-protein kinase GDT family (family) [23-469]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0065007 (biological regulation), GO:0051093 (negative regulation of developmental process), GO:0050793 (regulation of developmental process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0005773 (vacuole), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)