Protein: N-alpha-acetyltransferase 30 (EC 2.3.1.256) (L-A virus GAG protein N-acetyltransferase subunit MAK3) (Maintenance of killer protein 3) (N-terminal acetyltransferase C complex catalytic subunit MAK3) (NatC complex subunit MAK3) (NatC catalytic subunit) (Q03503)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Catalytic component of the NatC N-terminal acetyltransferase, which catalyzes acetylation of the N-terminus Met of L-A virus GAG protein and possibly GRH1.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus {ECO:0000269|PubMed:14562095}.
Sequence: MEIVYKPLDIRNEEQFASIKKLIDADLSEPYSIYVYRYFLNQWPELTYIAVDNKSGTPNIPIGCIVCKMDPHRNVRLRGYIGMLAVESTYRGHGIAKKLVEIAIDKMQREHCDEIMLETEVENSAALNLYEGMGFIRMKRMFRYYLNEGDAFKLILPLTEKSCTRSTFLMHGRLAT
InterPro domains: - IPR044542: N-alpha-acetyltransferase 30-like (family) [3-161]
- IPR016181: Acyl-CoA N-acyltransferase (homologous_superfamily) [13-159]
- IPR000182: GNAT domain (domain) [3-159]
Interaction partners: - N-alpha-acetyltransferase 35, NatC auxiliary subunit
- N-terminal acetyltransferase A complex catalytic subunit ARD1
- N-terminal acetyltransferase B complex catalytic subunit NAT3
- N-alpha-acetyltransferase 38, NatC auxiliary subunit
- N-terminal acetyltransferase A complex subunit NAT1
- N-alpha-acetyltransferase NAT5
- N-terminal acetyltransferase B complex subunit MDM20
- Small nuclear ribonucleoprotein-associated protein B
- N-alpha-acetyltransferase 40
- ADP-ribosylation factor-like protein 3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016410 (N-acyltransferase activity), GO:0016407 (acetyltransferase activity), GO:0008080 (N-acetyltransferase activity), GO:0034212 (peptide N-acetyltransferase activity), GO:0004596 (peptide alpha-N-acetyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:0051604 (protein maturation), GO:0043412 (macromolecule modification), GO:0010467 (gene expression), GO:0031365 (N-terminal protein amino acid modification), GO:0006474 (N-terminal protein amino acid acetylation), GO:0043543 (protein acylation), GO:0006473 (protein acetylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:1902494 (catalytic complex), GO:0005737 (cytoplasm), GO:0140535 (intracellular protein-containing complex), GO:0031248 (protein acetyltransferase complex), GO:1990234 (transferase complex), GO:0031414 (N-terminal protein acetyltransferase complex), GO:1902493 (acetyltransferase complex)