Protein: histone deacetylase (Q5ADP0)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus
Sequence: MYTELPFDELKVDPNQKKRIAYFYDADIGNYAYGAGHPMKPHRIRMAHSLIMNYGLYKKMEIYRAKPATKQEMCQFHTDEYIDFISRVNPDNLDLFTKEQIKFNVGDDCPVFDGLFEYCGISGGGSMEGAARLNRGKCDIAINYAGGLHHAKKSEASGFCYLNDIVLGIIELLRYHPRVLYIDIDVHHGDGVEEAFYTTDRVMTCSFHKYGEFFPGTGELRDIGVGKGKYHSVNVPLRDGIDDATYKSVFEPVISKIIEWYQPSAIVLQCGGDSLSGDRLGCFNLSMNGHANCINYVKSFNIPMMVVGGGGYTMRNVARTWAYESGLLNNVKLPDELPYNEYYEYYGPDYKLDVRSSNMFNQNSPEFLDKILTNIIANLENTKHAPSVQMNEVPNDPEDLGDVEEDTAMAIDTKGGSEMSRDAQIQPDNEFYEDDEKDKGEKAIIDNKHEDQDSMQVDKSEEPVVEQKDKPQDENNVTGDNIEEDQPQEVNPIEEQPSVEKSVVVVEDKLEEVKPVEQKVEEPKEVVDKPEDKHEDKPAETLTETTTESKPEDQPMEDAAKLTEEELKEIEELNKSS
InterPro domains: - IPR000286: Histone deacetylase HDAC (family) [146-273]
- IPR023696: Ureohydrolase domain superfamily (homologous_superfamily) [19-380]
- IPR023801: Histone deacetylase domain (domain) [37-324]
- IPR037138: Histone deacetylase domain superfamily (homologous_superfamily) [7-395]
- IPR003084: Class I/II Histone deacetylase HDAC (family) [8-471]
Interaction partners: - Transcriptional regulator
- Transcriptional regulatory protein SDS3
- Chromatin modification-related protein EAF3
- Histone deacetylase
- Ume1p
- Transcription regulator
- PHD-type domain-containing protein
- 4-nitrophenylphosphatase
- Histone acetyltransferase type B subunit 2
- Zinc finger PHD-type domain-containing protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0033558 (protein lysine deacetylase activity), GO:0019213 (deacetylase activity), GO:0016811 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0098732 (macromolecule deacylation), GO:0016570 (histone modification), GO:0035601 (protein deacylation), GO:0016575 (histone deacetylation), GO:0006476 (protein deacetylation), GO:0070932 (histone H3 deacetylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0000785 (chromatin), GO:1902494 (catalytic complex), GO:0140513 (nuclear protein-containing complex), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0000118 (histone deacetylase complex), GO:0043229 (intracellular organelle), GO:0070210 (Rpd3L-Expanded complex), GO:0043228 (non-membrane-bounded organelle), GO:0043233 (organelle lumen), GO:0070822 (Sin3-type complex), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0005634 (nucleus), GO:0031981 (nuclear lumen), GO:0005694 (chromosome), GO:0000228 (nuclear chromosome)