Protein: ATP-dependent zinc metallopeptidase, putative (Q387Q0)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MDPLSRDARASNLPSYYRGFYDAQQRRPTKNVEPSVTQAFGGAFLAAVPLAALYFFLRRRSAAAVKVAAPNAKPSGFFADVMKAMQKQMNPLGDKNFRVDVTDTKFKDVIGIPEAVEEIQQYVKFLQTPERFTRLGARLPKGCLLTGQPGTGKTLLAKAVAGEAGVPFFSCSGADFIEVYAGSGPKRVRELFAEAKKVAPSVVFLDEIDAVGTRGGEQDAGGVTSEENRTVNQLLAELDGLGASEAVVVFAATNFMDNIDKALLREGRFDRKIEVPMPDRQAREDLFRHYLKRIVASDVEVKAQRLAGLTPGVSPAAISTIVNEAALAAAVRGDGEVTEQTLLPAVDDVLLGKKHRSYMTDAALRRVALHESGHALVAWLLPQQPDVVKLSVTPRGCAAGFTQQLGREALDMHTDLSLFTDLCVLLAGRLAEATRYDGLTTGAQDDYQRATQAAIQQFLSFGMSQSVGLLAYEPQRLNEGRIYQRHSEKAQAMAEVEAARLVEVAQRFTQTLIAANANTLHRVADALVVKRELLSDELAALMGKRGTVRLTKEAKEALAEFLRKAEEHRPSFSDVTA
InterPro domains: - IPR000642: Peptidase M41 (domain) [359-538]
- IPR003960: ATPase, AAA-type, conserved site (conserved_site) [247-265]
- IPR003593: AAA+ ATPase domain (domain) [139-279]
- IPR003959: ATPase, AAA-type, core (domain) [143-276]
- IPR037219: Peptidase M41-like (homologous_superfamily) [358-547]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [85-348]
- IPR050928: ATP-dependent Zinc Metalloprotease (family) [38-566]
Interaction partners: - Prohibitin
- Prohibitin
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0044085 (cellular component biogenesis), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0016043 (cellular component organization), GO:0043170 (macromolecule metabolic process), GO:0006091 (generation of precursor metabolites and energy), GO:0006508 (proteolysis), GO:0051604 (protein maturation), GO:0043933 (protein-containing complex organization), GO:0006996 (organelle organization), GO:0010467 (gene expression), GO:0022607 (cellular component assembly), GO:0007005 (mitochondrion organization), GO:0045333 (cellular respiration), GO:0065003 (protein-containing complex assembly), GO:0016485 (protein processing), GO:0051259 (protein complex oligomerization), GO:0034982 (mitochondrial protein processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005740 (mitochondrial envelope), GO:0019866 (organelle inner membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031966 (mitochondrial membrane), GO:0005743 (mitochondrial inner membrane)