Protein: Phospholipid-transporting ATPase (EC 7.6.2.1) (Q5B018)
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362033}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362033}.
Sequence: MASGRAPGRHPAAGRDDDLLQLEESTPIYNTGRPPPVNDESLLRQYNIDDSENAQPRPSVSYDNFVGGRVTPHAGAHATGSAPPVHAGVYMNDPYSGQDVSRTYSQTSGLDNYQRYSMDEYEGGHGYYDMTGQDPMEGDSRMRERNSILSMGGGLMGRAKHMLGMKPEYSEMDLPLTEAGARAARADSTVSEDGPPHAKKSSKPSFKFGFGRRTVDSSTLGPRIIQLNNPPANAVHKFVDNHVSTAKYNIVTFLPKFLYEQFSKYANLFFLFTAVLQQIPNVSPTNRYTTIGPLVIVLLVSAIKELVEDYKRRSSDKSLNYSKTQVLKGSTFHETKWVDVAVGDIVRVESEQPFPADLVLLASSEPEGLCYIETANLDGETNLKIKQAIPETSHLVSPADLSRLSGRIRSEQPNSSLYTYEATLTMHAGGGERELPLAPDQLMLRGATLRNTPWIHGVVVFTGHETKLMRNATATPIKRTAVERMVNIQILMLVSILVALSVVSSVGDLIIRQTEKDKLTYLDYGSTNPGKQFIMDIFTYWVLYSNLVPISLFVTIEIVKYSQAFLINSDLDIYYDVTDTPATCRTSSLVEELGQIEYIFSDKTGTLTCNMMEFKECTIGGIQYGEDVAEDRRATVEDGVEVGVHDFKKLRQNLESHPTKDAIHHFLTLLATCHTVIPERSEADPDKIKYQAASPDEGALVEGAARMGYKFSNRKPRSVIITVAGQEYEYELLAVCEFNSTRKRMSTIFRCPDGRIRIYIKGADTVILERLHQDNPIVEGTLQHLEEYASDGLRTLCLAMREIPEDEFQQWYQIFDKAATTVGGNRAEELDKAAELIEKDFYLLGATAKEDRLQDGVPDTIHTLQTAGIKIWVLTGDRQETAINIGMSCKLISEDMTLLIVNEDSAEATRDNLTKKLQAVQSQTEAEQMALIIDGRSLTFALEKDMEKLFLDLAVLCKAVVCCCSRVSPLQKALVVKLVKRHLKSLLLAIGDGANDVSMIQAAHVGVGISGVEGLQAARSADVSIAQFRYLRKLLLVHGAWSYHRISRVILYSFYKNIALYMTQFWYSFQNAFSGEVIYESWTLSFYNVFFTVLPPFAMGICDQFISARLLDRYPQLYQLGQKGLFFKRHSFWSWIANGFYHSLLLYIVSQLIFLYDLPQADGKVAGHWVWGSALYTAVLATVLGKAALITNIWTKYTFIAIPGSMIIWLAFLPAYGYAAPAIGFSEEYYGTIPRLFTSPIFYLMAIVLPCICLLRDYAWKYAKRMYYPQHYHHVQEIQKYNVQDYRPRMEQFQKAIRKVRQVQRMRKQRGYAFSQADEGGQMRVVNAYDTTRGRGRYGEMTSSRNLV
InterPro domains: - IPR008250: P-type ATPase, A domain superfamily (homologous_superfamily) [323-472]
- IPR001757: P-type ATPase (family) [530-1073]
- IPR032630: P-type ATPase, C-terminal (domain) [1018-1270]
- IPR023299: P-type ATPase, cytoplasmic domain N (homologous_superfamily) [607-820]
- IPR036412: HAD-like superfamily (homologous_superfamily) [595-1045]
- IPR006539: P-type ATPase, subfamily IV (family) [238-1277]
- IPR044492: P-type ATPase, haloacid dehalogenase domain (domain) [582-1041]
- IPR018303: P-type ATPase, phosphorylation site (ptm) [602-608]
- IPR023214: HAD superfamily (homologous_superfamily) [841-1030]
- IPR032631: P-type ATPase, N-terminal (domain) [225-291]
- IPR023298: P-type ATPase, transmembrane domain superfamily (homologous_superfamily) [236-1269]
Interaction partners: - SWIRM domain protein Fun19, putative
- LEM3/CDC50 family protein
- Phospholipid-transporting ATPase
- Aspergillus nidulans myosin V homolog
- GTP-binding protein ypt1
- Uncharacterized protein
- TeaA receptor TeaR
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0140657 (ATP-dependent activity), GO:0140326 (ATPase-coupled intramembrane lipid transporter activity), GO:0005319 (lipid transporter activity), GO:0140303 (intramembrane lipid transporter activity), GO:0140327 (flippase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0065008 (regulation of biological quality), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0010817 (regulation of hormone levels), GO:0006810 (transport), GO:0008104 (protein localization), GO:0009914 (hormone transport), GO:0060918 (auxin transport), GO:0009926 (auxin polar transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0031982 (vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle)