wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Protein PsiE (P0A7C8)
Organism: Escherichia coli (strain K12)
Function: Not known
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Sequence: MTSLSRPRVEFISTILQTVLNLGLLCLGLILVVFLGKETVHLADVLFAPEQTSKYELVEGLVVYFLYFEFIALIVKYFQSGFHFPLRYFVYIGITAIVRLIIVDHKSPLDVLIYSAAILLLVITLWLCNSKRLKRE
InterPro domains: - IPR020948: Phosphate-starvation-induced PsiE-like (family) [19-131]
- IPR009315: Phosphate-starvation-induced PsiE (family) [1-136]
Interaction partners: - Protein PhoH
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0015079 (potassium ion transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0015267 (channel activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0005261 (monoatomic cation channel activity), GO:0015078 (proton transmembrane transporter activity), GO:0005267 (potassium channel activity), GO:0046873 (metal ion transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0034220 (monoatomic ion transmembrane transport), GO:0098660 (inorganic ion transmembrane transport), GO:0006810 (transport), GO:0098655 (monoatomic cation transmembrane transport), GO:0098662 (inorganic cation transmembrane transport), GO:0006811 (monoatomic ion transport), GO:0071805 (potassium ion transmembrane transport), GO:0006812 (monoatomic cation transport), GO:0030001 (metal ion transport), GO:0006813 (potassium ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Probable glutamate carboxypeptidase LAMP1 (EC 3.4.17.21) (Protein LIKE AMP1) (Q7Y228)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts in association with AMP1 to suppress ectopic stem cell niche formation in the shoot apical meristem (SAM) independently of cytokinin signaling pathway.
Subcellular location: Endoplasmic reticulum membrane {ECO:0000305|PubMed:25673776}; Single-pass type II membrane protein {ECO:0000255}.
Sequence: MSKSKSLAFVIAALSYSFFSLFSSPPKSHYHELFISTSFSDNASVALNLHTLTRRPHVAGTVANAEAAEYVRSVFTSSALKSHVVAYQVSLTYPVHRSLVLTPTDSAKPITFLLEQEKLGDNPYANEVMPTFHGYAKSGNVSGPVVYANYGRVEDFVRLKKDMGVNVSGAVVIARYGQIYRGDIVKNAYEAGAVGVVIYTDKRDYGGDEWFPASKWMPPSGVQVGTVYNGLGDPTTPGWASVDGCERLSDEAVELSGDVPLIPSLPVSAADAEVILKTVVGDVSDGDVYPVGPGPGVLNLSYIGETVIAKIENVIGVIEGEEEPDRYVILGNHRDAWTFGAVDPNSGTAVLMEIAQRLDKLQKRGWKPRRTIILCNWDAEEYGLIGSTEWVEENREMLSSRAVAYLNVDCAVSGPGFHASATPQLDELIKVAAQEVRDPDNATQTIYESWIGSSDSVVIRRLGGGGSDYASFVQHVGVPGVDMSFGRGYPVYHSMYDDFTWMEKFGDPMFQRHVAMASVLGLVALRLADEEIIPFNYTSYALELKKSAEDLENEKLGHNIDVSTLIKSIEDLSTAAKHISLEKEAIKGALKVRELNDRLMMAERALTDRDGLSERPWYKHLIYGPSKYDDYGSKSFPGVDDAIDNAKKLNTKASWENVQHQIWRVSRAIRHASLVLKGELI
InterPro domains: - IPR039373: Transferrin receptor protein 1/Glutamate carboxypeptidase 2-like (family) [29-679]
- IPR007484: Peptidase M28 (domain) [313-500]
- IPR007365: Transferrin receptor-like, dimerisation domain (domain) [560-676]
- IPR046450: PA domain superfamily (homologous_superfamily) [89-315]
- IPR003137: PA domain (domain) [141-223]
- IPR036757: Transferrin receptor-like, dimerisation domain superfamily (homologous_superfamily) [534-678]
Interaction partners: - Cytochrome P450 78A7
- Uridine 5'-monophosphate synthase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0008233 (peptidase activity), GO:0008238 (exopeptidase activity), GO:0016805 (dipeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0008380 (RNA splicing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Putative uncharacterized oxidoreductase YDR541C (EC 1.1.1.-) (Q03049)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Not known
Sequence: MSNTVLVSGASGFIALHILSQLLKQDYKVIGTVRSHEKEAKLLRQFQHNPNLTLEIVPDISHPNAFDKVLQKRGREIRYVLHTASPFHYDTTEYEKDLLIPALEGTKNILNSIKKYAADTVERVVVTSSCTAIITLAKMDDPSVVFTEESWNEATWESCQIDGINAYFASKKFAEKAAWEFTKENEDHIKFKLTTVNPSLLFGPQLFDEDVHGHLNTSCEMINGLIHTPVNASVPDFHSIFIDVRDVALAHLYAFQKENTAGKRLVVTNGKFGNQDILDILNEDFPQLRGLIPLGKPGTGDQVIDRGSTTDNSATRKILGFEFRSLHESVHDTAAQILKKQNRL
InterPro domains: - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [2-337]
- IPR050425: NAD(P)-dependent dehydratase-like (family) [4-311]
- IPR001509: NAD-dependent epimerase/dehydratase (domain) [5-262]
Interaction partners: - Uncharacterized oxidoreductase YDL114W
- Small ribosomal subunit protein uS19
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS3
- Large ribosomal subunit protein eL32
- Large ribosomal subunit protein uL23
- Small ribosomal subunit protein eS21B
- Small ribosomal subunit protein uS15
- Ubiquitin-ribosomal protein eS31 fusion protein
- Large ribosomal subunit protein uL15
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor), GO:0018455 (alcohol dehydrogenase [NAD(P)+] activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0030447 (filamentous growth), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:1901615 (organic hydroxy compound metabolic process), GO:0006066 (alcohol metabolic process), GO:0044107 (cellular alcohol metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006629 (lipid metabolic process), GO:0016125 (sterol metabolic process), GO:1902652 (secondary alcohol metabolic process), GO:0008204 (ergosterol metabolic process), GO:0008202 (steroid metabolic process), GO:0016128 (phytosteroid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Cyclic GMP-AMP synthase-like receptor (Tc-cGLR) (cGLR) (EC 2.7.7.86) (D6WI29)
Organism: Tribolium castaneum (Red flour beetle)
Function: Nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (2',3'-cGAMP) from ATP and GTP and plays a key role in innate immunity. Acts as a key sensor of double-stranded RNA (dsRNA), the presence of dsRNA in the cytoplasm being a danger signal that triggers the immune responses. Directly binds dsRNA, activating the nucleotidyltransferase activity, leading to synthesis of 2',3'-cGAMP, a second messenger that binds to and activates Sting, thereby triggering the antiviral immune response via activation of the NF-kappa-B transcription factor Rel (Relish) (By similarity).
Sequence: MENILNDINKRFISLPEEDVRGNKQILESVLRTFVEQMKTQDPLFKALFRRVFYGGSFYDGLKVGKPEEFDLDILLHIPIYAQPVLNESNVPGFVWLKLNNLDGWLRQPEGRVYKDFRKKFLADNDFLDTGKTLRWMESLVQKTLNTLPWVNNATCELTNEFGTFHINWWKGGPAMTLGISHSSGEKIMDVDLVACFVFSGDKWPINGYRSNPFPSTKPEFFIVPKKPQGPVNPQGRYWSLSFQEQERVLIDNKNRLKPAVKLIKKLKEKTHPNIASYYIKTVFLHIIEQKDQSFWNKSLREVFMTTLREYNEFIADQSIPYYWCRKNNLIGHLAPITLNNISNRIGYIIKDIENNPENIAKHLLTKEEYTKYIQGEDVMAEALPALPASQTSSCVII
InterPro domains: - IPR046906: Mab-21-like, HhH/H2TH-like domain (domain) [257-346]
- IPR046903: Mab-21-like, nucleotidyltransferase domain (domain) [58-253]
- IPR024810: MAB21L/Cyclic GMP-AMP synthase-like receptor (family) [57-351]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003725 (double-stranded RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0002376 (immune system process), GO:0006955 (immune response), GO:0042221 (response to chemical), GO:1901698 (response to nitrogen compound), GO:0010033 (response to organic substance), GO:0043331 (response to dsRNA), GO:0014070 (response to organic cyclic compound), GO:0043330 (response to exogenous dsRNA)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Non-structural protein V (P0C774)
Organism: Measles virus (strain Ichinose-B95a) (MeV) (Subacute sclerose panencephalitis virus)
Function: Plays an essential role in the inhibition of host immune response. Prevents the establishment of cellular antiviral state by blocking interferon-alpha/beta (IFN-alpha/beta) production and signaling pathway. Interacts with host IFIH1/MDA5 and DHX58/LGP2 to inhibit the transduction pathway involved in the activation of IFN-beta promoter, thus protecting the virus against cell antiviral state. Blocks the type I interferon signaling pathway by interacting with host TYK2 and thereby inhibiting downstream STAT1 and STAT2 phosphorylation. Moderately affects the type II interferon signaling.
Subcellular location: Host cytoplasm {ECO:0000250}.
Sequence: MAEEQARHVKNGLECIRALKAEPIGSLAVEEAMAAWSEISDNPGQDRATCKEEEAGSSGLSKPCLSAIGSTEGGAPRIRGQGSGESDDDAETLGIPSRNLQASSTGLQCYHVYDHSGEAVKGIQDADSIMVQSGLDGDSTLSGGDDESENSDVDIGEPDTEGYAITDRGSAPISMGFRASDVETAEGGEIHELLKLQSRGNNFPKLGKTLNVPPPPNPSRASTSETPIKKGHRREIGLIWNGDRVFIDRWCNPMCSKVTLGTIRARCTCGECPRVCEQCRTDTGVDTRIWYHNLPEIPE
InterPro domains: - IPR028243: Paramyxovirus structural protein P/V, N-terminal domain (domain) [4-233]
- IPR024279: Paramyxovirinae protein V, zinc-binding domain (domain) [238-280]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0016032 (viral process), GO:0019080 (viral gene expression), GO:0019083 (viral transcription), GO:0039695 (DNA-templated viral transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0043657 (host cell), GO:0033643 (host cell part), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0033647 (host intracellular organelle), GO:0033648 (host intracellular membrane-bounded organelle), GO:0042025 (host cell nucleus)
Protein: T-box transcription factor T (Brachyury protein) (Protein T) (P79777)
Organism: Gallus gallus (Chicken)
Function: Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site.
Subcellular location: Nucleus {ECO:0000250|UniProtKB:O15178}.
Sequence: MGSPEDAGKAPAYRVDHLLSAVESELQAGSEKGDPTERELRVALEDGELWLRFKELTNEMIVTKNGRRMFPVLKVSVSGLDPNAMYSFLLDFVAADGHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHSFPETQFTAVTAYQNEEITALKIKYNPFAKAFLDAKERNDHKDMMEEAGDNQQSGYSQLGSWLIPGAGALCPPANPHSQFGAPLSLSPAHSCERYSPLRNHRSAPYPNPYTHRNNSPTAYTDNSSACLPMLQSHDNWSSLGVPTHTTMLPMSHSTGTATSSSQYPNLWSVSNSTITPAPQSSGMSNGLSSQFLRGSPVHYTALPHPVTATTSTSPLYDGGAPADLPDSQYDASAHTRLASMWTPITPPSM
InterPro domains: - IPR002070: Transcription factor, Brachyury (family) [17-290]
- IPR046360: T-box transcription factor, DNA-binding domain (domain) [39-222]
- IPR008967: p53-like transcription factor, DNA-binding domain superfamily (homologous_superfamily) [40-221]
- IPR001699: T-box transcription factor (family) [23-398]
- IPR036960: T-box superfamily (homologous_superfamily) [38-228]
- IPR018186: Transcription factor, T-box, conserved site (conserved_site) [49-141]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0097110 (scaffold protein binding), GO:0019904 (protein domain specific binding), GO:0051087 (chaperone binding), GO:0051087 (chaperone binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0051094 (positive regulation of developmental process), GO:0050793 (regulation of developmental process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0045597 (positive regulation of cell differentiation), GO:0045595 (regulation of cell differentiation), GO:0045666 (positive regulation of neuron differentiation), GO:0045664 (regulation of neuron differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: WbcN protein (Q56917)
Organism: Yersinia enterocolitica
Function: Not known
Sequence: MYEAGHNVMIISLTGETLVRPNDGIQLNELKLDKAPFSLFKGLFEVKKIIKKFKPDIVHSHMFHANLFARILRVFTKIPALICTAHNTNEGSSLRMLAYKYTDKLASLSTNVSQDAVDSFIHKGASSTGRMIAVSNGIDASQFDFSMDERKVKRSELGIFNDTPIILSVGRLTEAKDYPNLLTAFSLLIKDNSLQSFPQLFIVGTGHLDGYLKNMSKEFGIDKYVTLFGQRDDILQLMCAADIFVLSSEWEGFPLVITEAMACKKIIVATDAGGITEALGDCGSIVPIKDPNSLSQAINKMIKLSDNEKEILGNKARERIIQTNSIEKIIELGCLFILNLKNNC
InterPro domains: - IPR028098: Glycosyltransferase subfamily 4-like, N-terminal domain (domain) [3-141]
- IPR001296: Glycosyl transferase, family 1 (domain) [151-319]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0008194 (UDP-glycosyltransferase activity), GO:0035250 (UDP-galactosyltransferase activity), GO:0008378 (galactosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0005975 (carbohydrate metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0044262 (cellular carbohydrate metabolic process), GO:0009059 (macromolecule biosynthetic process), GO:0016051 (carbohydrate biosynthetic process), GO:0005976 (polysaccharide metabolic process), GO:0034637 (cellular carbohydrate biosynthetic process), GO:1903509 (liposaccharide metabolic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:1901137 (carbohydrate derivative biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0008653 (lipopolysaccharide metabolic process), GO:0044264 (cellular polysaccharide metabolic process), GO:0046379 (extracellular polysaccharide metabolic process), GO:0009103 (lipopolysaccharide biosynthetic process), GO:0033692 (cellular polysaccharide biosynthetic process), GO:0000271 (polysaccharide biosynthetic process), GO:0045226 (extracellular polysaccharide biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Protein S100-A3 (Protein S-100E) (S100 calcium-binding protein A3) (P33764)
Organism: Homo sapiens (Human)
Function: Binds both calcium and zinc. May be involved in calcium-dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:18083705}.
Sequence: MARPLEQAVAAIVCTFQEYAGRCGDKYKLCQAELKELLQKELATWTPTEFRECDYNKFMSVLDTNKDCEVDFVEYVRSLACLCLYCHEYFKDCPSEPPCSQ
InterPro domains: - IPR011992: EF-hand domain pair (homologous_superfamily) [3-92]
- IPR034325: S-100 (domain) [4-90]
- IPR013787: S100/CaBP-9k-type, calcium binding, subdomain (domain) [5-47]
- IPR001751: S100/Calcium binding protein 7/8-like, conserved site (conserved_site) [58-79]
Interaction partners: - Protein S100-A16
- Protein S100-A2
- Hornerin
- Protein S100-A10
- Protein S100-A1
- Protein S100-A13
- Protein-arginine deiminase type-3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0001501 (skeletal system development), GO:0060348 (bone development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030312 (external encapsulating structure), GO:0005615 (extracellular space), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0031974 (membrane-enclosed lumen), GO:0012505 (endomembrane system), GO:0005576 (extracellular region), GO:0030141 (secretory granule), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0031012 (extracellular matrix), GO:0043230 (extracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043233 (organelle lumen), GO:0070062 (extracellular exosome), GO:0043227 (membrane-bounded organelle), GO:0060205 (cytoplasmic vesicle lumen), GO:0031983 (vesicle lumen), GO:0099503 (secretory vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0062023 (collagen-containing extracellular matrix), GO:0034774 (secretory granule lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0065010 (extracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031982 (vesicle), GO:1903561 (extracellular vesicle), GO:0097708 (intracellular vesicle), GO:0005634 (nucleus), GO:0005856 (cytoskeleton)
Protein: MA3 DOMAIN-CONTAINING TRANSLATION REGULATORY FACTOR 4 (MA3 domain-containing protein 7) (Q9STL9)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in target of rapamycin (TOR)-regulated translation control, especially under energy-deficient conditions.
Subcellular location: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00768}. Cytoplasm, cytosol {ECO:0000269|PubMed:29084871}.
Sequence: MATREWFVMNAQQTKLALESPPLFAVKKDDDKDHTCDTGEEPYALVGSPVFNPLEDYKREVVSIIDEYFSSGDVEVAASDLMDLGLSEYHPYFVKRLVSMAMDRGNKEKEKASVLLSRLYALVVSPDQIRVGFIRLLESVGDLALDIPDAVNVLALFIARAIVDEILPPVFLARAKKTLPHSSQGFQVILVSENSYLSAPHHAELVETKWGGSTHITVEETKRKISEFLNEYVENGDTREACRCIRELGVSFFHHEIVKSGLVLVMESRTSEPLILKLLKEATEEGLISSSQMAKGFSRVADSLDDLSLDIPSAKTLFESIVPKAIIGGWLDEDSFKERSDQNGGSENLRRFKKDAETIIQEYFLSDDIPELIRSLEDLGLPEYNPVFLKKLITLAMDRKNKEKEMASVFLASLHMEMFSTEDFINGFIMLLESAEDTALDILAASDELALFLARAVIDDVLAPLNLEEISNSLPPKSTGSETIRSARSLISARHAGERLLRSWGGGTGWAVEDAKDKIWKLLEEYEVGGVISEACRCIRDLGMPFFNHEVVKKALVMAMEKKNDRMLNLLQECFAEGIITTNQMTKGFGRVKDSLDDLSLDIPNAEEKFNSYVAHAEENGWLHRDFGCSTDS
InterPro domains: - IPR016024: Armadillo-type fold (homologous_superfamily) [54-627]
- IPR003891: Initiation factor eIF-4 gamma, MA3 (domain) [56-633]
- IPR039778: Programmed cell death protein 4 (family) [28-627]
Interaction partners: - F-box protein At5g18160
- Cytochrome P450, family 705, subfamily A, polypeptide 18
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0043021 (ribonucleoprotein complex binding), GO:0043022 (ribosome binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042594 (response to starvation), GO:0009991 (response to extracellular stimulus), GO:0009314 (response to radiation), GO:0009416 (response to light stimulus), GO:0031667 (response to nutrient levels), GO:0009642 (response to light intensity), GO:0009646 (response to absence of light)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)