Protein: Ly49 stimulatory receptor 3 (Q8K3H4)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
Sequence: MSKQDVPCSTVRFKKSSGLQYQVRPEETQRPREAGWRVPWQLTVIATGILLSLRLVAVAMLVTNIFQYSNENHELQKTHKRQHNSSTMEKDIKLKEEMLRNMSVESVHYNAFLDLINREQNRWYKKTKTVLASPQHTGGCDEMHWFCYGIKCYYFTMDIRIWRECKQTCQNYSLSFLKIDDKDELKFLQDHIIRDNYWIGSSYNNKKKEWAWIDNSPFDLDFVARTLLRKTGYCLYFSMSGLHDDDCGKRYLCICEKGMDKFPAPLCSVKETSHSAV
InterPro domains: - IPR013600: Ly49-like, N-terminal (domain) [38-155]
- IPR016186: C-type lectin-like/link domain superfamily (homologous_superfamily) [128-264]
- IPR052013: Mouse Killer cell lectin-like receptors (family) [1-263]
- IPR016187: C-type lectin fold (homologous_superfamily) [103-259]
- IPR001304: C-type lectin-like (domain) [140-257]
- IPR033992: Natural killer cell receptor-like, C-type lectin-like domain (domain) [142-257]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0023057 (negative regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0002684 (positive regulation of immune system process), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0002682 (regulation of immune system process), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0048522 (positive regulation of cellular process), GO:0031341 (regulation of cell killing), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:0002831 (regulation of response to biotic stimulus), GO:0032103 (positive regulation of response to external stimulus), GO:0050776 (regulation of immune response), GO:0010646 (regulation of cell communication), GO:0002697 (regulation of immune effector process), GO:0002833 (positive regulation of response to biotic stimulus), GO:0080134 (regulation of response to stress), GO:0031343 (positive regulation of cell killing), GO:0009966 (regulation of signal transduction), GO:0050778 (positive regulation of immune response), GO:0032101 (regulation of response to external stimulus), GO:0031349 (positive regulation of defense response), GO:0002699 (positive regulation of immune effector process), GO:0031347 (regulation of defense response), GO:0045089 (positive regulation of innate immune response), GO:0045088 (regulation of innate immune response), GO:0002703 (regulation of leukocyte mediated immunity), GO:0001910 (regulation of leukocyte mediated cytotoxicity), GO:0002705 (positive regulation of leukocyte mediated immunity), GO:0001912 (positive regulation of leukocyte mediated cytotoxicity), GO:0002706 (regulation of lymphocyte mediated immunity), GO:0042269 (regulation of natural killer cell mediated cytotoxicity), GO:0002708 (positive regulation of lymphocyte mediated immunity), GO:0045954 (positive regulation of natural killer cell mediated cytotoxicity), GO:0002717 (positive regulation of natural killer cell mediated immunity), GO:0002715 (regulation of natural killer cell mediated immunity)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009986 (cell surface)