Protein: Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 5.6.1.1) (p60 katanin) (Q38CB9)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Cytoplasm, cytoskeleton, spindle pole {ECO:0000256|ARBA:ARBA00004647}.
Sequence: MDDDVGLQKAIYSSLQSKRTQDAFNRFSRNAPSHGTVRSFPRNGKRNALLREGIMPTVPRSQQVRSTTGWTFSQFGDYTDRPPWVNPLDEESCIPNMPVRLQQPSDRVPGWTLMCSGGRIQRQNAMGSNILFICEEVHYAQNTKIHCNDLLALRTVAPLPQGKNIACFTAQIQSLVSQGRYAMFGMGITPRAGDERQGFCVALVHYDSSGGIFLSVEKWRMTEQDTFERLELLEPMKTLRLIRERVTITLLVSSEHFSLSINGEVVCPTLHAPGVRLGESLPILLATGGKISVREVAVVEGHKPPANKLYGRPPPFTLSPKKSDTNKKGIPIVEEEPLCSSGKAAFPDKVSNRKGKVVDKAVPKDKVLNSVAPCAPPGIAPELLERIEAEIIERSPNVEWDDIAGIPEAKRLLKEAIILPLLVPELFTGVVQPWKGVLLFGPPGTGKTMLARAVATSAKTTFFNISASSLISKYFGESEKIVRSLFHLARHYAPSTIFFDEVDALMSARGGNEHEASRRIKSEMLQQFDGLCTENDKRVLVLATTNRPWDLDEAMRRRLEKRIYIPLPDKAGRLSLLKKQTATLSLDPSVDLEEISDKRTEGFSGADMNLVVRDAAMMPMRRLIADRSPAEIAAMKEGGKMIVSPVTMNDFEDALKKIQPSVSQSSIKQFEKWAEELGSV
InterPro domains: - IPR003593: AAA+ ATPase domain (domain) [433-569]
- IPR028596: Katanin p60 subunit A1 (family) [36-680]
- IPR041569: AAA ATPase, AAA+ lid domain (domain) [589-625]
- IPR003959: ATPase, AAA-type, core (domain) [437-567]
- IPR015415: Spastin/Vps4, C-terminal (domain) [638-678]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [395-676]
- IPR050304: Microtubule-severing AAA ATPase (family) [360-679]
Interaction partners: - ATP-dependent protease subunit HslV
- Uncharacterized protein
- Katanin, putative
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0016887 (ATP hydrolysis activity), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0008092 (cytoskeletal protein binding), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0015631 (tubulin binding), GO:0016462 (pyrophosphatase activity), GO:0043014 (alpha-tubulin binding), GO:0017111 (ribonucleoside triphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0006996 (organelle organization), GO:0030030 (cell projection organization), GO:0022607 (cellular component assembly), GO:0044782 (cilium organization), GO:0070925 (organelle assembly), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0060271 (cilium assembly), GO:0120031 (plasma membrane bounded cell projection assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0005737 (cytoplasm), GO:0120025 (plasma membrane bounded cell projection), GO:0099568 (cytoplasmic region), GO:0043227 (membrane-bounded organelle), GO:0005929 (cilium), GO:0032838 (plasma membrane bounded cell projection cytoplasm), GO:0097014 (ciliary plasm)