wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Ammonium transporter (Q59UP8)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein
Sequence: MSGNFTGTGTGGDVFKVDLNEQFDRADMVWIGTASVLVWIMIPGVGLLYSGISRKKHALSLMWAALMAACVAAFQWFWWGYSLVFAHNGSVFLGTLQNFCLKDVLGAPSIVKTVPDILFCLYQGMFAAVTAILMAGAGCERARLGPMMVFLFIWLTVVYCPIAYWTWGGNGWLVSLGALDFAGGGPVHENSGFAALAYSLWLGKRHDPVAKGKVPKYKPHSVSSIVMGTIFLWFGWYGFNGGSTGNSSMRSWYACVNTNLAAATGGLTWMLVDWFRTGGKWSTVGLCMGAIAGLVGITPAAGYVPVYTSVIFGIVPAIICNFAVDLKDLLQIDDGMDVWALHGVGGFVGNFMTGLFAADYVAMIDGTEIDGGWMNHHWKQLGYQLAGSCAVAAWSFTVTSIILLAMDRIPFLRIRLHEDEEMLGTDLAQIGEYAYYADDDPETNPYVLEPIRSTTISQPLPHIDGVADGSSNNDSGEAKN
InterPro domains: - IPR029020: Ammonium/urea transporter (homologous_superfamily) [1-455]
- IPR024041: Ammonium transporter AmtB-like domain (domain) [29-435]
- IPR001905: Ammonium transporter (family) [17-440]
- IPR018047: Ammonium transporter, conserved site (conserved_site) [180-205]
Interaction partners: - Nitrogen-responsive transcriptional regulator
- Urea amidolyase
- Ammonium transporter
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0015267 (channel activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0008519 (ammonium transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0030447 (filamentous growth), GO:0006950 (response to stress), GO:0007154 (cell communication), GO:0009991 (response to extracellular stimulus), GO:0031668 (cellular response to extracellular stimulus), GO:0044182 (filamentous growth of a population of unicellular organisms), GO:0042594 (response to starvation), GO:0071496 (cellular response to external stimulus), GO:0033554 (cellular response to stress), GO:0036170 (filamentous growth of a population of unicellular organisms in response to starvation), GO:0009267 (cellular response to starvation), GO:0031669 (cellular response to nutrient levels), GO:0031667 (response to nutrient levels), GO:0006995 (cellular response to nitrogen starvation), GO:0043562 (cellular response to nitrogen levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Oxysterol-binding protein (A0A1D8PHG1)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Sequence: MSNSKSSSEETAKSSSWTSFLKSIASFNGDLSSLTAPPFILSPTSLVEYSQYWAEHPDLFIAPSLIKTTENPAKEEIEAINLQQMIAVTRWFISTLKSQYCSRNESMGSEKKPLNPFLGEVFVGKWQDDKTGETDLVSEQVSHHPPVTAYAIKNKKHGVVLQGYNGITSSISTTSINIKQYGHALLKYPEIDETFLITLPPLHIEGLITAAPFVELEGISYIQASSGHIAVIEYSGRGWISGKKNTFKARIYRDAYASASKENALVTISGQWSGKSYIGKGSSTPTSKNDVFYDASKTPTHHLQVKPIEEQHKLESRKAWFKVAEAIKKSDYNLIATEKTLIENEQRKLRKQEKDAGITWETRWFDKIDYLNKDADAPIKDEFTNLTNISNLSIHNAPSGTLKDSKYDHGEAKHWRVNLKKLEDEKEIVF
InterPro domains: - IPR037239: Oxysterol-binding protein superfamily (homologous_superfamily) [13-427]
- IPR018494: Oxysterol-binding protein, conserved site (conserved_site) [139-150]
- IPR000648: Oxysterol-binding protein (family) [8-369]
Interaction partners: - Fructose-bisphosphate aldolase
- Phosphatidylinositol-3-phosphatase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0005319 (lipid transporter activity), GO:0097159 (organic cyclic compound binding), GO:0008289 (lipid binding), GO:0005496 (steroid binding), GO:0120013 (lipid transfer activity), GO:0015248 (sterol transporter activity), GO:0120015 (sterol transfer activity), GO:0032934 (sterol binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0061919 (process utilizing autophagic mechanism), GO:0071704 (organic substance metabolic process), GO:0140352 (export from cell), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0032940 (secretion by cell), GO:1901564 (organonitrogen compound metabolic process), GO:0006629 (lipid metabolic process), GO:1901575 (organic substance catabolic process), GO:0044248 (cellular catabolic process), GO:0006665 (sphingolipid metabolic process), GO:0006887 (exocytosis), GO:0044242 (cellular lipid catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0016042 (lipid catabolic process), GO:0006643 (membrane lipid metabolic process), GO:0030149 (sphingolipid catabolic process), GO:0019377 (glycolipid catabolic process), GO:0046466 (membrane lipid catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: uracil phosphoribosyltransferase (Q59QT3)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Sequence: MSVAKAVSKNVILLPQTNQLIGLYSIIRDQRTKRGDFVFYSDRIIRLLVEEGLNQLPVEEAIIKCHGGYEYKGAKFLGKICGVSIVRAGESMEMGLRDCCRSVRIGKILIQRDEETALPKLFYEKLPEDISERYVFLLDPMLATGGSAMMAVEVLLARGVKMDRILFLNLLAAPEGIKAFQDKYPDVKIITGGIDEKLDENKYIVPGLGDFGDRYYCI
InterPro domains: - IPR000836: Phosphoribosyltransferase domain (domain) [15-216]
- IPR029057: Phosphoribosyltransferase-like (homologous_superfamily) [2-217]
Interaction partners: - Cytosine deaminase
- Trifunctional uridine nucleosidase/nicotinamide riboside hydrolase/nicotinic acid riboside hydrolase
- Orotidine 5'-phosphate decarboxylase
- Uridine kinase
- Uridylate kinase
- Purine nucleoside phosphorylase
- Apyrase
- Zinc finger-containing protein
- Pho100p
- Pseudouridine-5'-phosphate glycosidase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016763 (pentosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0043094 (cellular metabolic compound salvage), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0008655 (pyrimidine-containing compound salvage), GO:0019438 (aromatic compound biosynthetic process), GO:0018130 (heterocycle biosynthetic process), GO:0034654 (nucleobase-containing compound biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062039 (biofilm matrix), GO:0062040 (fungal biofilm matrix)
Protein: Nicotinamide-nucleotide adenylyltransferase (Q5AL24)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Sequence: MSKGRFLKPLQEFLTSKSDFSIIYNTSTTGSTSSFINPTTQRVCILDSSFNPPHLGHYALIEESLTKNYDNIPITNKVVLLLLSVKNADKLHPKPESFDKRLDMMYLMANDLSKKYPVNIAIGLTNHAKFVDKSLSVLNYIKETQNHHQERNLIKLTFLVGFDTLIRIFDPKYYLPDKLSNSLENFMKNTDLFCLTRLDNSFSQLEQSKYIDDIKRGDHEEIPSHWSDNIYLLPPKKEIEINQRGGEINQEIDVATISSSSIRKQIEIGDHPDGKTWKSQVLPDIANYIIKEDLYKQS
InterPro domains: - IPR005248: Nicotinate/nicotinamide nucleotide adenylyltransferase (family) [43-295]
- IPR014729: Rossmann-like alpha/beta/alpha sandwich fold (homologous_superfamily) [40-296]
Interaction partners: - Glutamine-dependent NAD(+) synthetase
- IMP-specific 5'-nucleotidase 1
- Nucleotidase
- Nicotinamide-nucleotide adenylyltransferase
- Nicotinate-nucleotide pyrophosphorylase [carboxylating]
- NAD(+) diphosphatase
- Nicotinate phosphoribosyltransferase
- Ribosylnicotinamide kinase
- NAD-dependent histone deacetylase HST3
- NADH/NAD(+) kinase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0016887 (ATP hydrolysis activity), GO:0016740 (transferase activity), GO:0016787 (hydrolase activity), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides), GO:0016779 (nucleotidyltransferase activity), GO:0016462 (pyrophosphatase activity), GO:0070566 (adenylyltransferase activity), GO:0017111 (ribonucleoside triphosphate phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0030447 (filamentous growth), GO:0042221 (response to chemical), GO:0009607 (response to biotic stimulus), GO:0051716 (cellular response to stimulus), GO:0030447 (filamentous growth), GO:0006950 (response to stress), GO:0044182 (filamentous growth of a population of unicellular organisms), GO:0036180 (filamentous growth of a population of unicellular organisms in response to biotic stimulus), GO:0006979 (response to oxidative stress), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0034599 (cellular response to oxidative stress), GO:0062197 (cellular response to chemical stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062039 (biofilm matrix), GO:0062040 (fungal biofilm matrix)
Protein: MIND complex subunit (Q5AH01)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Sequence: MDFQSDYEKIDLSKQDFQYVFNNILQAIMAKLNLHLPAAQNDPLKEQVSTILEEFLINTFDNSKYSILADGLDLQNVSIHDILSLKTLENVEKIDSEITIQLRKIFQEFEQETVDVTKLRRDLPKQASEMYNDIIKQTDGEVSEIINMIEQQSQEYQKVQQAHNNTDDRFEKIIESMDFSQINQNYNDHLQLLNETNKNLPSLKIEFEKYNRTVQFLEDAYQQQLKEMDG
InterPro domains: - IPR013950: Kinetochore Mis14/Nsl1 (family) [5-227]
Interaction partners: - Kinetochore protein mis13
- Kinetochore-associated protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0022402 (cell cycle process), GO:0007049 (cell cycle), GO:0016043 (cellular component organization), GO:0007059 (chromosome segregation), GO:1903047 (mitotic cell cycle process), GO:0000278 (mitotic cell cycle), GO:0098813 (nuclear chromosome segregation), GO:0006996 (organelle organization), GO:0000070 (mitotic sister chromatid segregation), GO:0140014 (mitotic nuclear division), GO:0048285 (organelle fission), GO:0000819 (sister chromatid segregation), GO:0051276 (chromosome organization), GO:0000280 (nuclear division)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098687 (chromosomal region), GO:0099080 (supramolecular complex), GO:0000939 (inner kinetochore), GO:0000922 (spindle pole), GO:0043229 (intracellular organelle), GO:0000775 (chromosome, centromeric region), GO:0000776 (kinetochore), GO:0043228 (non-membrane-bounded organelle), GO:0000779 (condensed chromosome, centromeric region), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0005819 (spindle), GO:0005694 (chromosome), GO:0000793 (condensed chromosome), GO:0015630 (microtubule cytoskeleton)
Protein: Low-affinity Zn(2+) transporter (A0A1D8PGN5)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Membrane; Multi-pass membrane protein
Sequence: MNSDSISQVFEYLNKRDECPTDNDYNGNIGTRISSIFVIMVTSAIGTLLPLLSSKYSFIRLPPMVYFICKYFGSGVIVATAFIHLLEPAADSLGNKCLTGPITEYPWAFGICLMTLFLLFFFELLAYQGIDRKIAKESQLDNQGPHTHSHFGDASMYVKKDDEEEDLENQNEKQADANPYPSHFAHAQEHQDPDVMGTTVNDQSKEQYYGQLLGVFVLEFGVMFHSVFIGLALAVSGDEFKSLYIVLVFHQMFEGLGLGTRIATTNWARHRYTPWILAICYTLCTPIAIAVGLGVRKSYPPGSRRALITNGVFDSISAGILLYTGIVELMAHEFLYSGEFKGPGGFKNMLLAYFVMCWGAGLMALLGKWA
InterPro domains: - IPR003689: Zinc/iron permease (family) [30-366]
- IPR004698: Zinc/iron permease, fungal/plant (family) [20-370]
Interaction partners: - Zn(2+) transporter
- Csr1p
- pH-regulated antigen PRA1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0005385 (zinc ion transmembrane transporter activity), GO:0046873 (metal ion transmembrane transporter activity), GO:0046915 (transition metal ion transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0034220 (monoatomic ion transmembrane transport), GO:0098739 (import across plasma membrane), GO:0098660 (inorganic ion transmembrane transport), GO:0006810 (transport), GO:0098655 (monoatomic cation transmembrane transport), GO:0098657 (import into cell), GO:0098662 (inorganic cation transmembrane transport), GO:0099587 (inorganic ion import across plasma membrane), GO:0006811 (monoatomic ion transport), GO:0098659 (inorganic cation import across plasma membrane), GO:0006812 (monoatomic cation transport), GO:0071577 (zinc ion transmembrane transport), GO:0030001 (metal ion transport), GO:0071578 (zinc ion import across plasma membrane), GO:0000041 (transition metal ion transport), GO:0006829 (zinc ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Amino acid permease/ SLC12A domain-containing protein (A0A1D8PU37)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Cell membrane; Multi-pass membrane protein
Sequence: MSSSSTASEVHKAPVVKNIEKQDMDMYSASSSSAPKTTWNNFIDSFHRADGKTSAESKDQRISKTELRIMSLSTGLGTGLLVASGSKLRAAGPAGVLVAYFITGICMLAPTINSVSELAIAYPGLPGGFQSYYAKFIDESLGFALGWNYAFQWMCVLALELVTSSMIIKFWTTTVNPDVFVAIFFVFVTLINMGGAKVYAVFEASFNCCKILLLVGFVIFGLIIDVGGGPQGFIGGRYYHDPGAFTSFKGLASVFVTGAFSLGGSEFISLSASETRHPRASIRAASKLVYFKVIVLFLGSLTFVGLLVAYNNDRLMGSGDAASHASPYVLAAEMNGIRVLPHIINAVILISVVSVATAAMYSSPRLVQSLAEQGLGPKWLDYIDKKGRPTRAWFITVLAGLFGFIAAYEKQETVFVWLLSISGISFIMCWLFICVSHIRFRAALKYRGITLDQLAYVSPTGVWGSYLSVLINSLILIAQFWISLWPLGGDGKPNANSFFENYLGAPVFLVCYIGHKLWTRNWKLFKKVEDIDIDTHRMICDPELLALEDLEDKERYQKAPIWKKILIKCFD
InterPro domains: - IPR004841: Amino acid permease/ SLC12A domain (domain) [69-527]
- IPR050524: Amino Acid-Polyamine-Organocation Superfamily YAT (family) [41-565]
Interaction partners: - Quinate transporter
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0005342 (organic acid transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity), GO:0046943 (carboxylic acid transmembrane transporter activity), GO:0015171 (amino acid transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0006810 (transport), GO:1903825 (organic acid transmembrane transport), GO:1905039 (carboxylic acid transmembrane transport), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:0006865 (amino acid transport), GO:0015849 (organic acid transport), GO:0015711 (organic anion transport), GO:0003333 (amino acid transmembrane transport), GO:0046942 (carboxylic acid transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Homoserine O-acetyltransferase (Q5A948)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Sequence: MTYKDVTEEQLQTNPYVKLVPGQTIVEIPEYTLECGETLHNFPVAYKTWGKLNETADNALVICHALSGSSDVDDWWGELLGTDRAFDPSRYLIICINFLGSPYGSCSPVTIDKSTGKPYGPSFPLVTFKDDVGIQRLILDSLNVKRLAAVVGGSMGGMLALEYSAIYNNTGYVQKVVALATAARTSAWCISWNETQRQCIFSDPFYDDGYYYETGNKPDSGLSAARMAALLTYRSRNSFESRFGRKLGPRSPNDGGASPRTKHEEHSLLHNDGSKLINGAPVNEKYPPTYFSAQSYMRYNGSKFINRFDANCYIAISRKLDTNDLSRGRVNAPNDANGDPLVHVLKDLSTPTLVIGIESDHLFTITEQKLLADNIPNAIFETLDSEEGHDAFLLEFEKINSFITSFLNN
InterPro domains: - IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [14-409]
- IPR000073: Alpha/beta hydrolase fold-1 (domain) [58-395]
- IPR008220: Homoserine/serine acetyltransferase MetX-like (family) [8-408]
Interaction partners: - Homoserine dehydrogenase
- Aspartokinase
- cystathionine gamma-synthase
- Tryptophan synthase
- Cystathionine beta-synthase
- Homocysteine/cysteine synthase
- Threonine dehydratase
- Cystathionine beta-lyase
- Serine hydroxymethyltransferase, cytosolic
- 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0008374 (O-acyltransferase activity), GO:0016407 (acetyltransferase activity), GO:0016413 (O-acetyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006520 (amino acid metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006790 (sulfur compound metabolic process), GO:0006082 (organic acid metabolic process), GO:0000096 (sulfur amino acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:1901605 (alpha-amino acid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0006555 (methionine metabolic process), GO:0009066 (aspartate family amino acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062039 (biofilm matrix), GO:0062040 (fungal biofilm matrix)
Protein: Hsk3p (Q5ALU4)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Sequence: MSSSNTPNKQAISSNERQSIIRTTLTPPSSTTSGNHPDPSLSSSSATQRKLSHLNSQMAQLNANLCDFNDLLVTTCSQYQSIEKLGKIHASIFMAGHTVFEDENFN
InterPro domains: - IPR042332: DASH complex subunit Hsk3 (family) [3-106]
- IPR013183: DASH complex subunit Hsk3-like (family) [48-91]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0015631 (tubulin binding), GO:0008017 (microtubule binding), GO:0051010 (microtubule plus-end binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0071840 (cellular component organization or biogenesis), GO:0050794 (regulation of cellular process), GO:0051726 (regulation of cell cycle), GO:0016043 (cellular component organization), GO:0032886 (regulation of microtubule-based process), GO:0051128 (regulation of cellular component organization), GO:0010564 (regulation of cell cycle process), GO:0033043 (regulation of organelle organization), GO:0051983 (regulation of chromosome segregation), GO:0006996 (organelle organization), GO:0060284 (regulation of cell development), GO:0033047 (regulation of mitotic sister chromatid segregation), GO:0033044 (regulation of chromosome organization), GO:0033045 (regulation of sister chromatid segregation), GO:0051276 (chromosome organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098687 (chromosomal region), GO:0000940 (outer kinetochore), GO:0140513 (nuclear protein-containing complex), GO:0099080 (supramolecular complex), GO:0042729 (DASH complex), GO:0000776 (kinetochore), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000775 (chromosome, centromeric region), GO:0043228 (non-membrane-bounded organelle), GO:0000779 (condensed chromosome, centromeric region), GO:0043231 (intracellular membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome), GO:0005634 (nucleus), GO:0000793 (condensed chromosome)
Protein: Uncharacterized protein (G1UAZ9)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules
Subcellular location: Mitochondrion
Sequence: MSLFRSLQNSPSTISIFHNSSIPLSNKLYDILEKAYDTQPEKPKHEFQIDLMKNKMPTYDQYKLIVDKYLKGSTSKTILHNCFPFLHDSKTELYNSKGNVVTVKGVEWANKTFSPAEYQMIYDTFNKLQESSDQSINTIASNVFQAPLVVDWDNDVIAGDEETLKAILSKYN
InterPro domains: - IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [1-172]
- IPR012882: Putative redox protein Fmp46 (family) [1-172]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016209 (antioxidant activity), GO:0004601 (peroxidase activity), GO:0016491 (oxidoreductase activity), GO:0016684 (oxidoreductase activity, acting on peroxide as acceptor), GO:0051920 (peroxiredoxin activity), GO:0140824 (thioredoxin-dependent peroxiredoxin activity), GO:0008379 (thioredoxin peroxidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0030447 (filamentous growth)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062039 (biofilm matrix), GO:0062040 (fungal biofilm matrix)