Protein: Rho-type GTPase activating protein Rga4 (B6K719)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Sequence: MDDTSLASFKTLDNDENPGFDVEPRLRCITCEKLLSEGVFLTVNNNFYHGNCFRCEKCGKTLAVRDAVAFTNSNQPICKDCVEVCKACKSPILDMAIITGMDAYHSTCFFCSSCNTKITEAIFARRNNQLFCMKCLQITDAVTSPTTRGHSRSVSGASFFKASSNNCNRYSYLSSPVPKLGAELSLSAAAATFAQRVVSPIDMNQNTIAERLAVPDVSSISASTPVDPSLPLGSNSAKPALRLYTSNPIIASSTENSNVIPEVVQLSDGSDLSNNESSGTAFSAPNSVATKHASLHVPLVAAQVNDKENEAAVHTPITSPVSVTYSPKDHITLAQEKQGSIAAAAAQLPAGSATANSSARRPVQIPRSVPTTPEHLRDSLNRLRSVSNTSTGSNVLGDNNFRRVSSEVSQPHIPKSVNAVEDPVQCTSPVNEPRTSTSTVHSITPTGARKVAGEAIASKPRVPSNSPFNSAAYRAKSLSFIQDPAERELYAGQGDVSNSSLVRLSGIFSSNVFDETENDARDLVSKMAGLHVQRAVLLMEISSLLRMKDRSPALTPNRFKQEFIADVNRGLDSLRKSFQPELASLLLKRDALSATVEKLQNAYSASMEETAYLNVKNAELLGINNQLEREIASKKEEYSKKRQSTFGFSRHFRNRHSTTDKDEVTSSSSRESHSRLQQVASSLGFRPREKYNPSESPQQQPANLEHKGSFSRRFLWRRDSKHPSSKAKNRASSVMSFSDLKITEEDEIPSFGMCKLCGNYSKNLPRHYQDCLSQAMDGQYQAQRQVQVNPLVETSSFDPQRYTLTRVPHLITACIGFVEKYGLDYEGLYRKSGATSQMKRIVSLLENGNTELGPNEDISAVTSVLKQYLRNLPNPIITFDQYYPLIEASGIRKPAEKLIGIKRVISNLPSIHGQVLRLIMFHLANVVKMSHLNLMNSKNLAVVFSPTLIRDPDNSRDVLDMAMKNLCLHFMIDHVEELF
InterPro domains: - IPR000198: Rho GTPase-activating protein domain (domain) [786-979]
- IPR001781: Zinc finger, LIM-type (domain) [26-136]
- IPR008936: Rho GTPase activation protein (homologous_superfamily) [753-979]
- IPR050729: Rho GTPase-activating protein (family) [178-979]
Interaction partners: - Clathrin heavy chain
- Rho-type GTPase activating protein Rga7
- Rho-type GTPase activating protein
- Rho-type GTPase activating protein Rga2
- Tropomyosin
- Rho family GTPase Cdc42
- Rho family GTPase Rho2
- Rho family GTPase Rho5
- GTP-binding protein RHO3
- Rho family GTPase Rho1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0008047 (enzyme activator activity), GO:0060589 (nucleoside-triphosphatase regulator activity), GO:0051020 (GTPase binding), GO:0030695 (GTPase regulator activity), GO:0005096 (GTPase activator activity), GO:0031267 (small GTPase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0023052 (signaling), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0051716 (cellular response to stimulus), GO:0065009 (regulation of molecular function), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0050790 (regulation of catalytic activity), GO:0044093 (positive regulation of molecular function), GO:0035556 (intracellular signal transduction), GO:0007264 (small GTPase mediated signal transduction), GO:0043085 (positive regulation of catalytic activity), GO:0051336 (regulation of hydrolase activity), GO:0043087 (regulation of GTPase activity), GO:0051345 (positive regulation of hydrolase activity), GO:0043547 (positive regulation of GTPase activity)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0045177 (apical part of cell), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0005938 (cell cortex), GO:0099568 (cytoplasmic region), GO:0045179 (apical cortex), GO:0099738 (cell cortex region)