Protein: Ribulose bisphosphate carboxylase large chain (RuBisCO large subunit) (EC 4.1.1.39) (Q6ENG6)
Organism: Oryza nivara (Indian wild rice) (Oryza sativa f. spontanea)
Function: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site.
Subcellular location: Plastid, chloroplast.
Sequence: MSPQTETKASVGFKAGVKDYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVVGEDNQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPTYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKSQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGEREMTLGFVDLLRDDFIEKDRARGIFFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAAANRVALEACVQARNEGRDLAREGNEIIRSACKWSPELAAACEIWKAIKFEFEPVDKLDS
InterPro domains: - IPR017443: Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal (domain) [24-144]
- IPR000685: Ribulose bisphosphate carboxylase, large subunit, C-terminal (domain) [154-462]
- IPR033966: RuBisCO (family) [1-474]
- IPR036422: RuBisCO large subunit, N-terminal domain superfamily (homologous_superfamily) [9-149]
- IPR020888: Ribulose bisphosphate carboxylase large subunit, type I (family) [9-475]
- IPR036376: Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily (homologous_superfamily) [148-477]
- IPR020878: Ribulose bisphosphate carboxylase, large chain, active site (active_site) [196-204]
Interaction partners: - Methylcrotonoyl-CoA carboxylase subunit alpha
- 4-hydroxyphenylpyruvate dioxygenase
- 2-isopropylmalate synthase
- Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
- Malonyl-CoA:ACP transacylase
- Enoyl-CoA hydratase
- Acyl-coenzyme A oxidase
- beta-ketoacyl-[acyl-carrier-protein] synthase III
- Ribulose bisphosphate carboxylase small subunit, chloroplastic
- Uncharacterized protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0005515 (protein binding), GO:0016829 (lyase activity), GO:0016830 (carbon-carbon lyase activity), GO:0046983 (protein dimerization activity), GO:0042803 (protein homodimerization activity), GO:0016831 (carboxy-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009620 (response to fungus), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0050832 (defense response to fungus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0043231 (intracellular membrane-bounded organelle)