Protein: [histone H3]-trimethyl-L-lysine(27) demethylase (A0A8M9QGN3)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Nucleus
Sequence: MYHIAEQYSGRNSWDSFPSSGPNRAPWAPGNNRHWAPPSSGGNYQSPSQNYMAGRSYPNKAYNNRPPGFSRDRLHAHPRDRGNGKEQRVPRSCGPTQNQHHNPERSTLNYSSGYEGHLSSSNNHGNQPHRYGGPHQQQRSTGRPPQTQGEKWTHSAQSRSFQGPSLKRPVPPHNLSQPLREPSPSRDDCPSKRSRSINSHQNFHPRDKYFINRPPPSHPPRPWSPAYKSSMSWSLSEKRSSPSRFQESSHSVTRDHTYRPYSHSSPPSSVPNQGLHNRKLTKQGPAHHPVHDHPDSPPRGAKGGWDCPSPANLTVPYSQQHQLPPPQRHTGPSSSPATSVPQPRSNTAQHGWKTQNRSGKHSNSEMGRTTYELDSHQSVGGDRKRSSGSKHISRQRSPIQPYNSAEGRVRDCTEWRNPETGLKKHDQKDSDSPSEPTTQTSERGQRAQRSEMKKSRHSKHQNKLKSTHKSALSKLDSELLKHIQAKKRHKERLRRKQKKEEGELTEDTKERIEKKIEERKKKKTREGRKGHDKKTIHKSGRKLGQVKKRAKEERKQGDRKSETSISKTASPNLGTLYPSDSDPLLDDLLADPLHLSYIEEENEFSQHTSGFILPCKSPVNNNHCSPCQSTLEINTKVLEVDEKSDSEPDHVDTSDDDSVGTHDVSGSNPSLLNTHVSEEEPIRCKEVVPGLHTAPDLLPAHCTYSEELLRLDPPTSPPVLSWQGSPVLDLGDDDEDVKEEDMIGVLRRPVLQPSPTHSSPLREAIEISTGVDYCHSDLAKLYGLPESSKAMDTEEEDEEKTDGEQKDGSPDASGSSETNKPHLHQMDTFKSPSSAMASHRYTYRGGPFGRPPPSALVGVKYSSSLSLGPEIHPPDQQSPPASSPTTEIPDQVIHSLIQPTDKDKESETEEEIMKTGAKEDKIEVKGEETKVQKMDEQMEVKLAEPTKDPASTSLEEKESVMSPATVQAKLVHSCELLLNQNSSPVSKVMKVSGSKSDQRENEGDRQKDQLKTPRKAIRTMKEEEPETCVGRSIKAKHHKKGDRGENKKDIMKDKAETNSSSLSSEDAQKQLVEIRTKQVVPENQQIEIKVGKTESHKIKREKETDVKKDAIKEDAIKADSSATGCTSCTTNLQSSSTMTLFTRPPMLERVNLRNQHELSKIPLKELKICLVKIESRGRQTFRASEIEEKSIPLDAINIRNNAAEVIRACKGADIKNKFRESYLLPSLSVKPDLSCRTPIPRDKLNPPTPSIYLESKRDAFSPVLLQFCTDSKNAVTVIRGLAGSLRLNLGLFSTKSLVEANSEHAVEVRTQVQQPADENWNHSGSAQTWPCESSRSHTTIAKYAQYQASSFQESLQEEKDSEDEDEEDKSKEKNEAKSNSQNNIGTTSTTTSSKQKAVGKIIKFGTNIDLSDPKRWKAQLQELLKLPAFMRVSSTANMLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWKAISDFCEKHGVDYLTGSWWPVLEDLYRSNIPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLNAYQYQLALERFEWNEVKKVKSIVPMIHVSWNVARTIKITDPNTFKMIKHCLMQSIKHIQILRDQLVSAGKKISYQSRVKDEPAYYCNECDLEVFDLLFVTSENSSRKTYVVHCEDCARERSPGLNGVVVLEQYRIDELMNMYDNFTLSAVPCCR
InterPro domains: - IPR048560: Lysine-specific demethylase 6A/B-like, GATA-like (domain) [1640-1699]
- IPR003347: JmjC domain (domain) [1415-1578]
- IPR048562: Lysine-specific demethylase 6A/B-like, C-terminal helical domain (domain) [1568-1622]
- IPR051630: Transcriptional Corepressor and Histone Demethylase (family) [828-1713]
- IPR046941: Lysine-specific demethylase 6, GATA-like domain superfamily (homologous_superfamily) [1633-1699]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009790 (embryo development), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:1904888 (cranial skeletal system development), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048701 (embryonic cranial skeleton morphogenesis), GO:0048703 (embryonic viscerocranium morphogenesis), GO:0048705 (skeletal system morphogenesis), GO:0048568 (embryonic organ development), GO:0001501 (skeletal system development), GO:0048562 (embryonic organ morphogenesis), GO:0009792 (embryo development ending in birth or egg hatching), GO:0043009 (chordate embryonic development), GO:0048704 (embryonic skeletal system morphogenesis), GO:0048706 (embryonic skeletal system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)