Protein: Metal transporter Nramp3.2 (A0A2K1ZPK4)
Organism: Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp
Function: Divalent metal transporter. Can transport manganese (Mn) and iron (Fe). Involved in the release of metals stored in the vacuole
Subcellular location: Vacuole membrane; Multi-pass membrane protein
Sequence: MPVEENYQPLLQEEEERAYDSDEKVLIIGVDSDTESGGSTVLPPFSWKKLWLFTGPGFLMSIAFLDPGNLEGDLQAGAIAGYSLLWLLLWATAMGLLVQLLSARLGVATGRHLAELCREEYPTWASMVLWIMAELALIGADIQEVIGSAIAIKILSNGFVPLWAGVTITACDCFIFLFLENYGVRKLEAVFAVLIGIMAVTFGWMFADAKPSASELFLGILIPKLSSRTIQQAVGVVGCIIMPHNVFLHSALVQSREIDHNKKDRVQEALRYYSIESTTALVISFVINLFVTTVFAKGFYGTELANSIGLVNAGQYLQDKYGGGFFPILYIWGIGLLAAGQSSTITGTYAGQFIMGGFLNLRLKKWLRALITRSCAIIPTMIVALVFDTSEDSLDVLNEWLNVLQSIQIPFALIPLLCLVSKEQIMGTFKIGPILKMVAWLVAALVMVINGYLLLDFFFNEVTGVAFTTVVCGFTGAYVAFIIYLISRGFTCFSRCCPSKQIEVE
InterPro domains: - IPR001046: NRAMP family (family) [35-487]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0046873 (metal ion transmembrane transporter activity), GO:0046915 (transition metal ion transmembrane transporter activity), GO:0005384 (manganese ion transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0042592 (homeostatic process), GO:0051234 (establishment of localization), GO:0048878 (chemical homeostasis), GO:0019725 (cellular homeostasis), GO:0055085 (transmembrane transport), GO:0050801 (monoatomic ion homeostasis), GO:0055082 (intracellular chemical homeostasis), GO:0098771 (inorganic ion homeostasis), GO:0034220 (monoatomic ion transmembrane transport), GO:0098660 (inorganic ion transmembrane transport), GO:0006810 (transport), GO:0098655 (monoatomic cation transmembrane transport), GO:0098662 (inorganic cation transmembrane transport), GO:0055080 (monoatomic cation homeostasis), GO:0006873 (intracellular monoatomic ion homeostasis), GO:0006811 (monoatomic ion transport), GO:0006812 (monoatomic cation transport), GO:0030003 (intracellular monoatomic cation homeostasis), GO:0030001 (metal ion transport), GO:0000041 (transition metal ion transport), GO:0006829 (zinc ion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031984 (organelle subcompartment), GO:0005794 (Golgi apparatus), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0098791 (Golgi apparatus subcompartment), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0005770 (late endosome), GO:0005802 (trans-Golgi network), GO:0097708 (intracellular vesicle)