wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: High-mobility group non-histone chromatin protein (B6K4P1)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Sequence: MPKAARKTRRKDPNAPKRNMSAFMFFSMSNREKIKEENPEATFGQIGSLLGKKWKTLTAVEKEPYEEKARKDKERYERECMKGPAKTGEPVKKETNSPPKAPSPKAPSPKAPSPTVPSNESEKNAETDSTKAEE
InterPro domains: - IPR009071: High mobility group box domain (domain) [15-86]
- IPR050342: High Mobility Group Box (HMGB) (family) [6-132]
- IPR036910: High mobility group box domain superfamily (homologous_superfamily) [2-97]
Interaction partners: - FACT complex subunit POB3
- FACT complex subunit
- Histone H2A
- Actin-like protein Arp8
- Actin-like protein Arp5
- RuvB-like helicase
- DNA-directed RNA polymerase
- Transcription factor TFIIH complex subunit Tfb1
- General transcription and DNA repair factor IIH subunit TFB4
- DNA-directed RNA polymerase I complex subunit Rpa49
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0008301 (DNA binding, bending)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0006325 (chromatin organization), GO:0043933 (protein-containing complex organization), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly), GO:0006334 (nucleosome assembly), GO:0071824 (protein-DNA complex subunit organization), GO:0006338 (chromatin remodeling), GO:0065004 (protein-DNA complex assembly), GO:0034728 (nucleosome organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Lipin Ned1 (B6K141)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Sequence: MQYVGRAFGSVSKTWNSINPATLTGAIDVIVVEQQDGSLACSPFHVRFGKFSLLRPSDKKVEFRVNNELTDFNMKLGDGGEAFFVFATENDVPQELQTSPLGSPSHSPSGSPKIQRPRSASNAATEGPMSQNWLRHARYSSDPGSCEPSTPTKSGSGSTTPTHEKRVMPKPELLQKAIELGKRLSGKELPAHVTDNGDIVMDMTGYKASELNRNIADFARETFKDEFPEIEKLIAEDEKGNLWFYASEEAKKSASPGITSSPITSTLPVATDDESESPNVSAPASPKSDSALMREDHLERMQSIREELTRSPSPSKQSYYYVKTLRLTSEQLSSLKLRPGKNDMSFTVNNGKSVCLANLYFWRYEDPVVISDIDGTITKSDALGHMFTFIGKDWTHPGVAKLYSDIVSNGYKIMYLTSRSIGQADSTRHYLWNIEQDGYTMPHGPVILSPDRTIAALHREVILRKPEIFKMACLRDLCGLFDVPPPKSPFYAGFGNRITDAISYNHVGVPPTRIFTINSAGEVHMELLQRSGYRSSYIYMNDLVDYFFPPVEVSVEPEVNTFTDVTYWRTPLPELSDDEDEPKSKKNTPKSQTKTSKKQGSPKPEQDLASNNDLEKEEDSENDMSAILARAMDLRDPEDNEMNDEAT
InterPro domains: - IPR023214: HAD superfamily (homologous_superfamily) [365-472]
- IPR026058: LIPIN family (family) [237-575]
- IPR031315: LNS2/PITP (domain) [368-526]
- IPR013209: Lipin/Ned1/Smp2 (LNS2) (domain) [323-549]
- IPR036412: HAD-like superfamily (homologous_superfamily) [363-517]
- IPR057124: Nuclear elongation and deformation protein 1-like, middle domain (domain) [169-255]
- IPR007651: Lipin, N-terminal (domain) [1-100]
Interaction partners: - Phosphatidate cytidylyltransferase Ptp4
- Diacylglycerol O-acyltransferase
- Phosphatidic acid phosphatase
- Nem1-Spo7 phosphatase complex catalytic subunit Nem1
- Phospholipid-diacylglycerol acyltransferase Plh1
- Phosphatidate cytidylyltransferase
- 1-acyl-sn-glycerol-3-phosphate acyltransferase
- Palmitoyl protein thioesterase-dolichol pyrophosphate phosphatase fusion 1
- Membrane bound O-acyltransferase
- Phospholipase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0016043 (cellular component organization), GO:0044249 (cellular biosynthetic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0061024 (membrane organization), GO:0006996 (organelle organization), GO:0010256 (endomembrane system organization), GO:0008610 (lipid biosynthetic process), GO:0006998 (nuclear envelope organization), GO:0007029 (endoplasmic reticulum organization), GO:0006997 (nucleus organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: vesicle-fusing ATPase (B6K5C2)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Subcellular location: Endosome membrane; Peripheral membrane protein
Sequence: MASVDFLSKAISLVKLAIDNDNKEQYTEAYKYYQNALDYFMMALKYENNENSKTLIRNKVVEYLDRAEQIKAFLQKQSVQAPVSNGNSLSQDAPKPGSGAANGLSDTADAEVKKLRGALSSAILSEKPNVKWDDVAGLENAKEALKETVLLPIKLPKLFSHGRKPWSGILLYGPPGTGKSFLAKAVATEAGSTFFSISSSDLVSKWQGESERLVRQLFEMARENKPSIIFIDEIDSLCGQRSDSESESSRRIKTEFLVQMNGVGRNESGVLILGATNIPWALDSAIRRRFEKRIYIPLPDLHARAKIFKLNVGNIPSELTNEDYKELAKLTEGYSGSDIATVVRDAIMEPVRRIHTATHFKTVYDPTTKSDMITPCSPGDPDAYEATWMDIDSERLLEPKLTVRDFYSAVRKVKPTLNQSDIERHIMFTKEFGAEG
InterPro domains: - IPR007330: MIT domain (domain) [3-80]
- IPR003960: ATPase, AAA-type, conserved site (conserved_site) [270-289]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [128-429]
- IPR045253: Vacuolar protein sorting-associated protein 4, MIT domain (domain) [5-77]
- IPR036181: MIT domain superfamily (homologous_superfamily) [1-92]
- IPR003593: AAA+ ATPase domain (domain) [165-300]
- IPR041569: AAA ATPase, AAA+ lid domain (domain) [321-359]
- IPR003959: ATPase, AAA-type, core (domain) [169-298]
- IPR050304: Microtubule-severing AAA ATPase (family) [24-433]
- IPR015415: Spastin/Vps4, C-terminal (domain) [373-433]
Interaction partners: - Endosomal sorting protein
- Vacuolar sorting protein Did2
- Vacuolar-sorting protein SNF7
- Vacuolar sorting protein Vps20
- Vacuolar sorting protein Did4
- MVB sorting pathway protein
- Vacuolar sorting protein Vps60
- Vacuolar sorting protein Vps24
- Vacuolar sorting protein
- BRO domain-containing protein 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0009894 (regulation of catabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0031329 (regulation of cellular catabolic process), GO:0010506 (regulation of autophagy)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0005769 (early endosome), GO:0031982 (vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0097708 (intracellular vesicle)
Protein: Tubulin alpha chain (B6K2P3)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin
Subcellular location: Cytoplasm, cytoskeleton
Sequence: MREIISIHVGQAGTQIGNACWELYCLEHGIQPDGYMSPEAMEGKRDNGFSTFFSETGQGKYVPRSIYVDLEPNVIDQVRTGTYRNLFHPEQLITGKEDASNNYARGHYTVGKELVDDVVERIRRIADNCSGLQGFLVFHSFGGGTGSGFGALLLERLAMDYTKKSKLQFSVYPAPQVSTSVVEPYNSVLTTHATLDLADCTFMVDNESCYDICRRNLDIERPSYENLNRLIAQVVSSITASLRFEGSLNVDLAEFQTNLVPYPRIHFPLVTYAPIVSAAKAFHESNSVQEITNHCFEPYNQMVKCDPRAGRYMATCLLYRGDVIPRDVQAAVATIKAKRTIQFVDWCPTGFKIGICDRPPQHVANSEIAKVDRAVCMLSNTTAIAEAWSRLDHKFDLMYSKRAFVHWYVGEGMEEGEFSEAREDLAALERDYEEVGQDSMDADYMEEEY
InterPro domains: - IPR018316: Tubulin/FtsZ, 2-layer sandwich domain (domain) [248-393]
- IPR003008: Tubulin/FtsZ, GTPase domain (domain) [3-246]
- IPR017975: Tubulin, conserved site (conserved_site) [142-148]
- IPR000217: Tubulin (family) [2-439]
- IPR008280: Tubulin/FtsZ, C-terminal (homologous_superfamily) [246-439]
- IPR002452: Alpha tubulin (family) [18-438]
- IPR036525: Tubulin/FtsZ, GTPase domain superfamily (homologous_superfamily) [1-268]
- IPR037103: Tubulin/FtsZ-like, C-terminal domain (homologous_superfamily) [269-383]
- IPR013838: Beta tubulin, autoregulation binding site (binding_site) [1-4]
- IPR023123: Tubulin, C-terminal (homologous_superfamily) [384-436]
Interaction partners: - Tubulin alpha chain
- Tubulin beta chain
- Dynein heavy chain, cytoplasmic
- Inner centromere protein Mis6
- Dynein intermediate chain Dic1
- EB1 family Mal3
- Actin
- Actin Act1
- Kinesin-like protein Cut7
- Kinesin-like protein cut7
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0040007 (growth), GO:0048589 (developmental growth), GO:0048856 (anatomical structure development), GO:0009653 (anatomical structure morphogenesis), GO:0016049 (cell growth), GO:0000902 (cell morphogenesis), GO:0060560 (developmental growth involved in morphogenesis), GO:0009826 (unidimensional cell growth)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043229 (intracellular organelle), GO:0043228 (non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0099513 (polymeric cytoskeletal fiber), GO:0005874 (microtubule), GO:0015630 (microtubule cytoskeleton)
Protein: Chromodomain protein Swi6 (B6JYE1)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Subcellular location: Nucleus
Sequence: MTYSITSLACTTCTLGGIETHLRQFKQHLHRHSAHVAMGNTTRTYKRSSGTRSSLSGSKKNQDQEASSSDSEVYEKISDHELDDEKEPKDNAPDDENAENKDAESEDSNDNDEGEEEYVVEKILDHRVKRGVFWYLLKWEGYDKPEDNTWSSEADCTGCKELIENYWAEHGGRPEKRTRKRTTRKTDSDAAEQPAPKSRRTSQRTASKAASGDEGTATRSTAKQADADIEPSDEEDVPVSKKSRAAAKSAEKTATKRRPGRPRKKAVSEEEEDTEFEAEEEEKEEVESQESDTAEVTTKKTKSTRKSKRRESKTVEAIESGEEDEAPELPTDEQLSLDKLEAMDSWEDLISSIDTIERRNDGSLQIYLTWKNGAISHHDSRITNKKCPQKMLEFYERHLTFRENANDDENEEGKEEGNDEDDMNDLVSD
InterPro domains: - IPR016197: Chromo-like domain superfamily (homologous_superfamily) [112-399]
- IPR023780: Chromo domain (domain) [118-168]
- IPR051219: Heterochromatin-associated chromo domain-containing protein (family) [100-408]
- IPR008251: Chromo shadow domain (domain) [338-404]
- IPR000953: Chromo/chromo shadow domain (domain) [117-178]
- IPR023779: Chromo domain, conserved site (conserved_site) [135-156]
Interaction partners: - [histone H3]-dimethyl-L-lysine(36) demethylase
- Histone-lysine N-methyltransferase
- Histone H3
- Uncharacterized protein
- Histone deacetylase
- Centromere-specific histone H3 CENP-A
- Chromodomain protein Chp1
- SHREC complex subunit Mit1
- Histone deacetylase
- Argonaute
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0016043 (cellular component organization), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0006259 (DNA metabolic process), GO:0006996 (organelle organization), GO:0090304 (nucleic acid metabolic process), GO:0006265 (DNA topological change), GO:0051276 (chromosome organization), GO:0071103 (DNA conformation change)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098687 (chromosomal region), GO:0000785 (chromatin), GO:0000792 (heterochromatin), GO:0043229 (intracellular organelle), GO:0000775 (chromosome, centromeric region), GO:0043228 (non-membrane-bounded organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005694 (chromosome)
Protein: Protein YOP1 (B6K529)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Subcellular location: Membrane; Multi-pass membrane protein
Sequence: MSYQQRIQQQLNVLDKRLSAFPVLNVMEQKVGVNKVYICLGLATVYFALLFLNFGGYLLTNTLAFVMPAFFSIYSLETPDKDDDTQWLTYYLITSFMTVLEYWIDFLLVWVPFYWLMKAIFLVWLALPRFSGASLIYRAIIRPYITPYVMRVMSRVNNAAAAGAPVPPPRSEKPAAAPAAAPAASATGAQL
InterPro domains: - IPR004345: TB2/DP1/HVA22 (family) [61-148]
Interaction partners: - Protein sey1
- Reticulon-like protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0010256 (endomembrane system organization), GO:0061024 (membrane organization), GO:0090158 (endoplasmic reticulum membrane organization), GO:0007029 (endoplasmic reticulum organization), GO:0071786 (endoplasmic reticulum tubular network organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031975 (envelope), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005783 (endoplasmic reticulum), GO:0005635 (nuclear envelope), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0031965 (nuclear membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Myosin type-2 heavy chain 1 (B6K4Y8)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Sequence: MSTASLEVLGINSSKNDMKEQDDKRWVWIPDPENAFVKACVIEELKDHQLRVRYNNFRDEKIVLEAETLPVNPSNFDSVDDMAELTHLNEPSIAYNLEQRYMSDLIYTYSGLFLVAINPYNLLPIYNKDIIQLYKDKTYGRKYPHIFSVADLAYNNLLEKKEHQSILVTGESGAGKTENTKRIIQYLASVANSSQYTEGQIEEQILQTNPILESFGNAQTVRNNNSSRFGKFIRIEFSASGEISNATIDWYLLEKSRVVRQSPEERSYHVFYQLIKGADEALRNKLLLSKTTDEYNYLKESSNTIDGVDDAAEFEKLLASMKTLNFTEQEMIASFKILSIVLLLGNITVVADRNGAARLPNPDEIDKICHLMGMKPEEFSQNLIRPKIRAGREWVFSARSQVQVASSLEALAKTIYERNFGWLVDRINQSLKNSGTTSRHFIGILDIAGFEIFKHNSFEQLCINYTNERLQQFFNHHMFVLEQEEYMRESIKWEFQDFGHDLQPTIDLIEKSKPIGILSCLDEECVMPKATDTTFTEKLNALWNGKSTKYKPSKFGCDGFTLTHYAADVEYKTEGWLEKNSDPLNENVANLIANSSNKHLASLFADYKDPVGSVTRTSKKKGVFRTVAQRHKEQLNQLMNQFGVTNPHFVRCIVPNQLKKAHVFNWPLVLEQLRCNGVLEGIRITRSGFPNRLTFNDFRLRYEIMVNVSKNNQYVESRKASLLILQELDVDSDLYRIGISKVFFRAGVLAILEKRRTEYLQRLMTGLQSCIRGAAQRKRYQKTLNAITASKLIEKNLYYYKDLAQFSWAKLFLTIRPLLSSTQNDEKLKKKDEELARVNYELKKSQASFRQAEDQRKATEDSIKNLEKVLETERSIAVDKEEILYRTQEKVNDLLETISKLESDISEKDERVNSFSEEMELLVKEHTQLVEASTKTDNELFETKEKLEAVLASNEELDEKVSTLTASLASANSQNEQLARENKSLSETVDELTSSEKNREELERAINELNTKWKSREQELLDKEKALEEELQTSNDNFSKLQEEKEQAQKQFKEALQSSNDVSAKLQQEKEQTQKQYEDALQKANDKSTRLQTEKDQVQSQLDQLRSDLKHSRSRFDEISKEGGELQAKLKRLEEANDDLESMKKIQQLTISDLEEKVSFLEADLKQLVNLKNEVADLKLKNGELQEQLSDMHVLKEKLNQRDNTLRSYSEEIDSLRSEVNTLQGYRDKYNALSSQSTSLKSSADKLKGELDQIKVYVNKFLHAEEELNRTRLQLNTSNEANSMLNEKIDLLTKERDSLEGEVHHGKERISLLQDTIQRQRGDLASVDELKDKIRTFESQISQLKGELKEEKNKVSTLTQYSKEAEILRSQLKKMQNIEEELNKAKSELKQVRSLRSEIELLKGKVGSQELLRSKNKELELRATELRKELSSVQERTKRKEQELQKLKTTLENEKMETKENLQRMFTPQRKTIFDLHERNASQAMQLLHHNWLLKALVVPSNARI
InterPro domains: - IPR036961: Kinesin motor domain superfamily (homologous_superfamily) [75-688]
- IPR004009: Myosin, SH3 domain (domain) [22-73]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [55-815]
- IPR001609: Myosin head, motor domain-like (domain) [71-758]
Interaction partners: - Myosin II light chain
- Myosin type-2 heavy chain 2
- Myosin II regulatory light chain Rlc1
- Tropomyosin
- Uncharacterized protein
- Formin Cdc12
- Alpha-actinin
- Cell division control protein Cdc15
- UCS-domain-containing protein Rng3
- Actin Act1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0016032 (viral process), GO:0046794 (transport of virus), GO:0019058 (viral life cycle), GO:0075733 (intracellular transport of virus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0036379 (myofilament), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0043229 (intracellular organelle), GO:0043292 (contractile fiber), GO:0043228 (non-membrane-bounded organelle), GO:0030016 (myofibril), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0099512 (supramolecular fiber)
Protein: Vacuolar-sorting protein SNF7 (B6K054)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Subcellular location: Endosome
Sequence: MSSFFRWFGGGNKEKDTAKDTIVKFQEMLSLFDKKEEKLEKQIEQQNEIARKNATANKRLALTALKRKKMYEAELAKIEGSRNNIEQQLYTIQNANLNFETLQAMRQGADAMKKIQKGMDADKVDQIMDRIRDQQAVSEEISTMISTPIGLNADMDEDELTAELEELQQVELDNKMLGAEKPPIHAPSLPSTGKVPTLPSVQKPQVLDEEEELRKLQAEFSM
InterPro domains: - IPR005024: Snf7 family (family) [20-202]
Interaction partners: - Vacuolar sorting protein
- Vacuolar sorting protein Vps24
- Vacuolar sorting protein Did4
- BRO1 domain-containing protein
- vesicle-fusing ATPase
- Vacuolar sorting protein Vps20
- Vacuolar sorting protein Did2
- Vacuolar sorting protein Vps60
- BRO domain-containing protein 1
- Vacuolar protein-sorting-associated protein 36
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0046907 (intracellular transport), GO:0051649 (establishment of localization in cell), GO:0006810 (transport), GO:0007034 (vacuolar transport), GO:0016192 (vesicle-mediated transport), GO:0016197 (endosomal transport), GO:0071985 (multivesicular body sorting pathway), GO:0032509 (endosome transport via multivesicular body sorting pathway), GO:0045324 (late endosome to vacuole transport), GO:0032511 (late endosome to vacuole transport via multivesicular body sorting pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: rRNA 2'-O-methyltransferase fibrillarin (B6JX17)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Subcellular location: Nucleus, nucleolus
Sequence: MAYTPGARGGRGGGRGGFRGGRGGGRGGGRGGFRGGRGGGRGGGRGGGRGGGRGGARGGAARGGAKVVVEPHRHAGVFIARGKEDLLVTRNLVPGESVYNEKRISVDSPDGTKVEYRVWNPFRSKLAAGILGGLDNIYIKPGAKVLYIGAANGTSVSHVADVVGPEGLVYAVEFSHRSGRDLLNMAKKRTNVIPIVEDARHVQKYRMLIGMVDVVFADVAQPDQARIVGLNAAAFLKNEGGVVISVKASCIDSTAEASVVFAREVKKMQEEKIKPQEQLTLEPYERDHCIIVGKYLRYQ
InterPro domains: - IPR029063: S-adenosyl-L-methionine-dependent methyltransferase superfamily (homologous_superfamily) [67-297]
- IPR020813: Fibrillarin, conserved site (conserved_site) [167-181]
- IPR000692: rRNA 2'-O-methyltransferase fibrillarin-like (family) [39-297]
Interaction partners: - U3 snoRNP-associated protein Rrp9
- Nucleolar protein 56
- 13 kDa ribonucleoprotein-associated protein
- Nucleolar protein 58
- U3 small nucleolar RNA-associated protein 22
- H/ACA ribonucleoprotein complex subunit CBF5
- U3 snoRNP protein Utp4
- H/ACA ribonucleoprotein complex subunit 2
- U3 small nucleolar RNA-associated protein 10
- U3 snoRNP-associated protein Nan1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0016070 (RNA metabolic process), GO:0034660 (ncRNA metabolic process), GO:0016074 (sno(s)RNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)