Protein: CDP-diacylglycerol--serine O-phosphatidyltransferase (A0A1D8PF32)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein
Sequence: MSDSSATGFSKHQESAIVSDSEGDAIDSELHMSANPPLLRRSSSLFSLSSKDDLPKPDSKEYLKFIDDNRHFSMIRNLHMADFITLLNGFSGFYSIISCLRYTLTGQTHYVQRAHFFILLGLFFDFFDGRVARLRNKSSLMGQELDSLADLVSFGVSPATIAFAIGFRTTVDVLFLAFWVLCGLTRLARFNISVNNIPKDKHGKSQYFEGLPIPTNLFWVGFMALLVYKDWIHDNLPFGIVFQDTSFEFHLVTIGFVLQGCAEISKSLKIPKP
InterPro domains: - IPR000462: CDP-alcohol phosphatidyltransferase (family) [79-233]
- IPR016271: CDP-diacylglycerol--serine O-phosphatidyltransferase, fungal (family) [49-273]
- IPR050324: CDP-alcohol phosphatidyltransferase class-I (family) [71-241]
- IPR043130: CDP-alcohol phosphatidyltransferase, transmembrane domain (homologous_superfamily) [71-260]
- IPR048254: CDP-alcohol phosphatidyltransferase, conserved site (conserved_site) [128-150]
- IPR004533: CDP-diacylglycerol--serine O-phosphatidyltransferase (family) [85-218]
Interaction partners: - Phosphatidylserine decarboxylase proenzyme 1, mitochondrial
- Phosphatidylserine decarboxylase proenzyme 2
- Phosphatidyl-N-methylethanolamine N-methyltransferase
- Phosphatidate cytidylyltransferase
- Phosphatidylethanolamine N-methyltransferase
- Lysophospholipid acyltransferase
- CDP-diacylglycerol--inositol 3-phosphatidyltransferase
- CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
- Tryptophan synthase
- Cardiolipin synthase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016780 (phosphotransferase activity, for other substituted phosphate groups), GO:0017169 (CDP-alcohol phosphatidyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0040007 (growth), GO:0009605 (response to external stimulus), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0071554 (cell wall organization or biogenesis), GO:0009607 (response to biotic stimulus), GO:0006807 (nitrogen compound metabolic process), GO:0051716 (cellular response to stimulus), GO:0030447 (filamentous growth), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0007154 (cell communication), GO:0044238 (primary metabolic process), GO:0009991 (response to extracellular stimulus), GO:0044182 (filamentous growth of a population of unicellular organisms), GO:0006575 (cellular modified amino acid metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0036180 (filamentous growth of a population of unicellular organisms in response to biotic stimulus), GO:0006629 (lipid metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0042594 (response to starvation), GO:0033554 (cellular response to stress), GO:0019637 (organophosphate metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0031668 (cellular response to extracellular stimulus), GO:0036171 (filamentous growth of a population of unicellular organisms in response to chemical stimulus), GO:0071496 (cellular response to external stimulus), GO:0006793 (phosphorus metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0036170 (filamentous growth of a population of unicellular organisms in response to starvation), GO:0046486 (glycerolipid metabolic process), GO:0042398 (cellular modified amino acid biosynthetic process), GO:0009267 (cellular response to starvation), GO:0006644 (phospholipid metabolic process), GO:0031667 (response to nutrient levels), GO:0090407 (organophosphate biosynthetic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0006658 (phosphatidylserine metabolic process), GO:0031669 (cellular response to nutrient levels), GO:0008610 (lipid biosynthetic process), GO:0045017 (glycerolipid biosynthetic process), GO:0006650 (glycerophospholipid metabolic process), GO:0008654 (phospholipid biosynthetic process), GO:0046474 (glycerophospholipid biosynthetic process), GO:0006646 (phosphatidylethanolamine biosynthetic process), GO:0046337 (phosphatidylethanolamine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)