wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Tim10-like domain-containing protein (Q57Z59)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MQSQMMLMQAMERYGMLDLANSALEQCWDICYDRNLTRHELVEGVLPDAKLQKMEACQRKCIARHFEVMRLMNASREQREKEMLQGLPPGSLGME
InterPro domains: - IPR035427: Tim10-like domain superfamily (homologous_superfamily) [2-86]
- IPR004217: Tim10-like (domain) [6-74]
Interaction partners: - Uncharacterized protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0009987 (cellular process), GO:0051641 (cellular localization), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0033036 (macromolecule localization), GO:0046907 (intracellular transport), GO:0006810 (transport), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0016043 (cellular component organization), GO:0051668 (localization within membrane), GO:0045184 (establishment of protein localization), GO:0006839 (mitochondrial transport), GO:0090151 (establishment of protein localization to mitochondrial membrane), GO:0006886 (intracellular protein transport), GO:0071705 (nitrogen compound transport), GO:0015031 (protein transport), GO:0072594 (establishment of protein localization to organelle), GO:0071702 (organic substance transport), GO:0008104 (protein localization), GO:0006996 (organelle organization), GO:0090150 (establishment of protein localization to membrane), GO:0061024 (membrane organization), GO:0072657 (protein localization to membrane), GO:0072655 (establishment of protein localization to mitochondrion), GO:0007005 (mitochondrion organization), GO:0033365 (protein localization to organelle), GO:0007006 (mitochondrial membrane organization), GO:0006605 (protein targeting), GO:0051205 (protein insertion into membrane), GO:0051204 (protein insertion into mitochondrial membrane), GO:0006626 (protein targeting to mitochondrion), GO:0070585 (protein localization to mitochondrion), GO:0007007 (inner mitochondrial membrane organization), GO:0045039 (protein insertion into mitochondrial inner membrane)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0098798 (mitochondrial protein-containing complex), GO:0031975 (envelope), GO:0016020 (membrane), GO:0005737 (cytoplasm), GO:0098796 (membrane protein complex), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005739 (mitochondrion), GO:0043229 (intracellular organelle), GO:0098800 (inner mitochondrial membrane protein complex), GO:0043227 (membrane-bounded organelle), GO:0005740 (mitochondrial envelope), GO:0019866 (organelle inner membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031966 (mitochondrial membrane), GO:0005743 (mitochondrial inner membrane)
Protein: Metallothionein-1X (MT-1X) (Metallothionein-IX) (MT-IX) (P80297)
Organism: Homo sapiens (Human)
Function: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids. May be involved in FAM168A anti-apoptotic signaling.
Sequence: MDPNCSCSPVGSCACAGSCKCKECKCTSCKKSCCSCCPVGCAKCAQGCICKGTSDKCSCCA
InterPro domains: - IPR018064: Metallothionein, vertebrate, metal binding site (binding_site) [13-31]
- IPR000006: Metallothionein, vertebrate (family) [1-61]
- IPR017854: Metallothionein domain superfamily (homologous_superfamily) [1-61]
- IPR023587: Metallothionein domain superfamily, vertebrate (homologous_superfamily) [1-61]
Interaction partners: - Metallothionein-1F
- Metallothionein-2
- Metallothionein-1M
- Metallothionein 1H-like protein 1
- Metallothionein-1H
- Metallothionein
- Metallothionein-1G
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0042592 (homeostatic process), GO:0051716 (cellular response to stimulus), GO:0048878 (chemical homeostasis), GO:0019725 (cellular homeostasis), GO:0042221 (response to chemical), GO:0050801 (monoatomic ion homeostasis), GO:0055082 (intracellular chemical homeostasis), GO:0098771 (inorganic ion homeostasis), GO:0010035 (response to inorganic substance), GO:0010033 (response to organic substance), GO:0070887 (cellular response to chemical stimulus), GO:0010038 (response to metal ion), GO:0034097 (response to cytokine), GO:0055080 (monoatomic cation homeostasis), GO:0006873 (intracellular monoatomic ion homeostasis), GO:0071241 (cellular response to inorganic substance), GO:0071310 (cellular response to organic substance), GO:0055070 (copper ion homeostasis), GO:0006878 (intracellular copper ion homeostasis), GO:0071248 (cellular response to metal ion), GO:0010043 (response to zinc ion), GO:0071345 (cellular response to cytokine stimulus), GO:0030003 (intracellular monoatomic cation homeostasis), GO:0071294 (cellular response to zinc ion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Putative pentatricopeptide repeat-containing protein At1g64310 (Q9C7V5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Sequence: MASQTQLRLIIYEFTRKIQTRLNTQKLHSFVTKSKLARDPYFATQLARFYALNDDLISARKLFDVFPERSVFLWNSIIRAYAKAHQFTTVLSLFSQILRSDTRPDNFTYACLARGFSESFDTKGLRCIHGIAIVSGLGFDQICGSAIVKAYSKAGLIVEASKLFCSIPDPDLALWNVMILGYGCCGFWDKGINLFNLMQHRGHQPNCYTMVALTSGLIDPSLLLVAWSVHAFCLKINLDSHSYVGCALVNMYSRCMCIASACSVFNSISEPDLVACSSLITGYSRCGNHKEALHLFAELRMSGKKPDCVLVAIVLGSCAELSDSVSGKEVHSYVIRLGLELDIKVCSALIDMYSKCGLLKCAMSLFAGIPEKNIVSFNSLILGLGLHGFASTAFEKFTEILEMGLIPDEITFSALLCTCCHSGLLNKGQEIFERMKSEFGIEPQTEHYVYMVKLMGMAGKLEEAFEFVMSLQKPIDSGILGALLSCCEVHENTHLAEVVAENIHKNGEERRSVYKVMLSNVYARYGRWDEVERLRDGISESYGGKLPGISWF
InterPro domains: - IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [4-547]
- IPR046960: Pentatricopeptide repeat-containing protein At4g14850-like, plant (family) [228-551]
- IPR002885: Pentatricopeptide repeat (repeat) [70-443]
- IPR046848: E motif (repeat) [490-551]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0043412 (macromolecule modification), GO:0090304 (nucleic acid metabolic process), GO:0016070 (RNA metabolic process), GO:0009451 (RNA modification), GO:1900864 (mitochondrial RNA modification), GO:0016071 (mRNA metabolic process), GO:0000959 (mitochondrial RNA metabolic process), GO:0016556 (mRNA modification), GO:0080156 (mitochondrial mRNA modification)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Uncharacterized protein, isoform C (M9NED4)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MDVPDDNFGPSKPCDKQPLAGNSSSATNSSSHTGGNGNVDSAFESSTAAGPSSGANQSSTGGAIDEQGSIGEQSAGVGQNIIEGDLLVLNANSTNVDLSTHRDGSSFKDSNTEQGKKSTMIKTSKTLNDKSQFERRRRRGRQRERHREPSTHRDDLEPCDLGLMGWTGEFPKLTPISNIESNSDKEPLVEDKKEDTTKKQAEADHTLHKSLKDARIVKRSMSTHSPPEHSRRSVRFSSHTPLTDETNIMKETSTETSLKVIFERLKQTGVERDLFIPSSENPRPRSNGSPVPKVAEMEHVAVVKCKTVAKQGAVVKGKAGLANPSNVMPQTPALTVTGKRVSKPKVPKGASPPSEGWTSTRAVKGNSRADYTNSSSCGSPIGNTNIRRRRAHAKAAPDKSKPCVRCAASVHPSGPKLCKKCIYEKGYANKKWMKKTGGNEDHYDDDDDSDFSMIEVTLENEISVQQAEKKQLENVNKQTVIKEQEVVVIGGRKAIAIIADPIGCNLKVIPNRQNLAGLKKISKDKCSSSLVQSLGDCHIGCQIVMAVMKIMTMKDRVNMAQVCKTWAMISQDKSVWRTVMLRDTHISNWPRFIRELANNCTRELDMLGVILPNPPDILATLDISVLKALRVLRTCPVDDQFLFKVFRELPQLLELRAICYSPTFNFLNLARQWSKIRVLQILMTDHRSKVESLDSLGDLVHLTELNIRGVNYIGSQDFRFLKKLVNLKVLVLSSCQGMDTEEFGQQVLPFLTSLRRLRLENKHMINTTFPLYHIMCGVAAACSVQQLELVNVEVDDLLTSLIGMCTTVTHLLLVPKCLQNSANVIYSVMRAVRENASQLRVFRLGLVTQLLSATGELYRGSKKDVIPVERPVPGIPLDDDLNYCAPDDRCIETDHTECVTFLPAKRLLMILRDVAPTTFVTFVKVNMFNSTMVTFLKRPQLKNK
InterPro domains: - IPR001810: F-box domain (domain) [544-577]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [659-848]
- IPR052283: Genomic Stability and Neuronal Morphogenesis Regulator (family) [189-937]
- IPR036047: F-box-like domain superfamily (homologous_superfamily) [543-590]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0006950 (response to stress), GO:0006952 (defense response), GO:0009617 (response to bacterium), GO:0098542 (defense response to other organism), GO:0043207 (response to external biotic stimulus), GO:0042742 (defense response to bacterium)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Receptor associated protein of the synapse (E9PJP9)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MGQDQTKQQIEKGLQLYQSNQTEKALQVWTKVLEKSSDLMGRFRVLGCLVTAHSEMGRYKEMLKFAVVQIDTARELEDADFLLESYLNLARSNEKLCEFHKTISYCKTCLGLPGTRAGAQLGGQVSLSMGNAFLGLSVFQKALESFEKALRYAHNNDDAMLECRVCCSLGSFYAQVKESMKIALQHGDRPLQALCLLCFADIHRSRGDLETAFPRYDSAMSIMTEIGNRLGQVQALLGVAKCWVARKALDKALDAIERAQDLAEEVGNKLSQLKLHCLSESIYRSKGLQRELRAHVVRFHECVEETELYCGLCGESIGEKNSRLQALPCSHIFHLRCLQNNGTRSCPNCRRSSMKPGFV
InterPro domains: - IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [2-305]
- IPR001237: 43kDa postsynaptic protein (family) [3-42]
- IPR018293: 43kDa postsynaptic, conserved site (conserved_site) [2-10]
- IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [306-351]
- IPR052480: Receptor-associated synaptic protein (family) [1-178]
- IPR019734: Tetratricopeptide repeat (repeat) [6-266]
- IPR019568: Rapsyn, myristoylation/linker region, N-terminal (domain) [1-80]
- IPR001841: Zinc finger, RING-type (domain) [310-350]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0007267 (cell-cell signaling), GO:0007154 (cell communication), GO:0099536 (synaptic signaling), GO:0099537 (trans-synaptic signaling), GO:0098916 (anterograde trans-synaptic signaling), GO:0007268 (chemical synaptic transmission), GO:0007271 (synaptic transmission, cholinergic)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005815 (microtubule organizing center), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005829 (cytosol), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005886 (plasma membrane), GO:0043228 (non-membrane-bounded organelle), GO:0005813 (centrosome), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0015630 (microtubule cytoskeleton)
Protein: Low molecular weight protein-tyrosine-phosphatase Wzb (EC 3.1.3.48) (P0AAB2)
Organism: Escherichia coli (strain K12)
Function: Dephosphorylates Wzc. Required for the extracellular polysaccharide colanic acid synthesis, probably involved in the export of colanic acid from the cell to medium. Involved in protection of cells against contact-dependent growth inhibition (CDI), probably due to the loss of a physical impediment to cell-cell contact.
Sequence: MFNNILVVCVGNICRSPTAERLLQRYHPELKVESAGLGALVGKGADPTAISVAAEHQLSLEGHCARQISRRLCRNYDLILTMEKRHIERLCEMAPEMRGKVMLFGHWDNECEIPDPYRKSRETFAAVYTLLERSARQWAQALNAEQV
InterPro domains: - IPR036196: Phosphotyrosine protein phosphatase I superfamily (homologous_superfamily) [1-142]
- IPR023485: Phosphotyrosine protein phosphatase I (domain) [3-141]
- IPR017867: Protein-tyrosine phosphatase, low molecular weight (family) [5-128]
- IPR050438: Low Molecular Weight Phosphotyrosine Protein Phosphatase (family) [3-146]
Interaction partners: - Tyrosine-protein kinase wzc
- Putative polysaccharide export protein Wza
- Tyrosine-protein kinase etk
- Lipopolysaccharide biosynthesis protein WzxC
- Putative O-antigen transporter
- UDP-glucose:undecaprenyl-phosphate glucose-1-phosphate transferase
- Low molecular weight protein-tyrosine-phosphatase Etp
- Lipid III flippase
- Mannose-1-phosphate guanylyltransferase
- Probable ECA polymerase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0004721 (phosphoprotein phosphatase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0004725 (protein tyrosine phosphatase activity), GO:0016791 (phosphatase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0006793 (phosphorus metabolic process), GO:0036211 (protein modification process), GO:0006796 (phosphate-containing compound metabolic process), GO:0043412 (macromolecule modification), GO:0016311 (dephosphorylation), GO:0006470 (protein dephosphorylation), GO:0035335 (peptidyl-tyrosine dephosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Oxidative stress-responsive serine-rich protein 1 (Oxidative stress-responsive protein 1) (Peroxide-inducible transcript 1 protein) (Q703I1)
Organism: Rattus norvegicus (Rat)
Function: Not known
Sequence: MKSEAKDGEEESLQTAFKKLRVDASGSIVSLSVGEGTSVRASVRTTVDDTKPKTMCAPKDSWHGSTRKSSRGAVRIQRRRRSKSPVLHPPKFIHCSTTASPSSSQLKQRSQTEPLDGSSGRGISTPKEFSTGENSTSLDINHTGAAIEPLRSSVLRLPSESKTEELSDATQVSPESLTANDLSDFQSVSKLSQGKPCVCVGKACQCKRWHDMEVYSFSGLQNVPPLAPERRSLEDYSQSLHTRTLSGSPRSCSEQARVYVDDVTIEDLAGYMEYYLYIPKKMSHMAEMMYT
InterPro domains: - IPR008494: Protein of unknown function DUF776 (family) [1-291]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0023056 (positive regulation of signaling), GO:0048584 (positive regulation of response to stimulus), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0009967 (positive regulation of signal transduction), GO:0010647 (positive regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0010646 (regulation of cell communication), GO:0030111 (regulation of Wnt signaling pathway), GO:0030177 (positive regulation of Wnt signaling pathway), GO:0060828 (regulation of canonical Wnt signaling pathway), GO:0090263 (positive regulation of canonical Wnt signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Large ribosomal subunit protein eL31 (60S ribosomal protein L31) (P62900)
Organism: Mus musculus (Mouse)
Function: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:36517592}.
Sequence: MAPAKKGGEKKKGRSAINEVVTREYTINIHKRIHGVGFKKRAPRALKEIRKFAMKEMGTPDVRIDTRLNKAVWAKGIRNVPYRIRVRLSRKRNEDEDSPNKLYTLVTYVPVTTFKNLQTVNVDEN
InterPro domains: - IPR000054: Large ribosomal subunit protein eL31 (family) [1-125]
- IPR023621: Large ribosomal subunit protein eL31 domain superfamily (homologous_superfamily) [14-125]
- IPR020052: Large ribosomal subunit protein eL31, conserved site (conserved_site) [62-76]
Interaction partners: - Large ribosomal subunit protein uL1
- Large ribosomal subunit protein eL24
- Large ribosomal subunit protein eL43
- Small ribosomal subunit protein uS19
- Large ribosomal subunit protein eL33
- Large ribosomal subunit protein eL32
- Small ribosomal subunit protein uS17
- Large ribosomal subunit protein eL29
- Large ribosomal subunit protein eL6
- Small ribosomal subunit protein uS14
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0019538 (protein metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006412 (translation), GO:0009059 (macromolecule biosynthetic process), GO:0006518 (peptide metabolic process), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:0010467 (gene expression), GO:0043043 (peptide biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0030054 (cell junction), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Uncharacterized protein (Q582T3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MANAALEENFVKAASLVREGNHIAAIGLYKTISSDEHITVAQKIRAFSNMSACYAAREQFAEALSAAKEALQMDDRNSKVHGRMAAAYHGLKHYEEASRHYARAYELDPNTILYKEQHQLVLELMRSGRGVASKDTLDSYYYRKGIEQGKEAMTKGEYLSAVRHFSKAIELHTKCASNGESNRGNGGGSVAADMAVLLCNRSAAYARAGRWSESLKDGMRAIEVHPTYARAFFRVGCAQHQLKRPQESCTALRRCLELDPSHGEAKNLMVEVEKLVAEACKTTEEREREREIQVREILERQNAEGATHAVGSRGRAHATSYVLCSYCNDGGHTREECPLLRRKRSRTS
InterPro domains: - IPR011990: Tetratricopeptide-like helical domain superfamily (homologous_superfamily) [4-310]
- IPR019734: Tetratricopeptide repeat (repeat) [44-262]
- IPR047150: SGT (family) [145-298]
- IPR036875: Zinc finger, CCHC-type superfamily (homologous_superfamily) [309-344]
Interaction partners: - Telomerase-associated protein, putative
- STI1 domain-containing protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)