Protein: Zinc finger protein 711 (Vitelline envelope protein) (A7Y7X5)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Transcription regulator required for brain development. Probably acts as a transcription factor that binds to the promoter of target genes, leading to activate their expression (By similarity).
Subcellular location: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:19117036}.
Sequence: MDQGGGILELHKDLKMPHTMIMPDFGMSGIAHLDGEHIVVSVPEAVMVSDVVTDEEGIMLETALEAEVVEEPDICQEDVITTEGVIMSESILGAEVAIQEALSGTADLIEETVPDQVFVAELMSPHIQSPLDHNLVSAEVMVTDADTVIDSHDTLQSDVTIKADDDVEDVKSTSEDYLMISLDEVGGKLDIEDTSLKISADVGQDDDGSKEDEFSSEVIKVYIFKADGDEDVEIGSTEVVEESDFPGRHTVMESVGSGRLPREKMVYMAVKDANQEDDLNCSEMTDQVYMEVIVGEEEAPAITEAQMEDSPVNKTIVPAAWATAYGSSLESKNGAATPYLQITDSISTSRALKQKIKKRRRGETRQCQTAVIIGPDGQPLTVYPCHICGKKFKSRGFLKRHMKNHPDHMFKKKYQCTDCEFTTNKKVSFHNHLESHKLIIKNEKIPEYTEYTRRYHEASPLSSNKLILRDKEPKLHKCKYCEYETAEQGLLNRHLLAVHSKNFAHVCVECAKGFRHPSELKKHMRTHTGEKPFHCQHCEFSCADQSNLKTHIKSKHGTDLPFKCGHCPQAFADDKELQRHAEIFQGHKTHQCPHCEHKSTNSSDLKRHIISVHTKDFPHKCDVCEKGFHRPSELKKHSETHKGNKVHQCRHCDFKTLDPFTLSRHILSVHTKDLPFKCKRCKRGFRHQNELKKHMKTHSGRKVYQCQYCEYNTTDASGFKRHVISIHTKDYPHRCDYCKKGFRRPSEKNQHIMRHHKETLL
InterPro domains: - IPR013087: Zinc finger C2H2-type (domain) [383-760]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [382-742]
- IPR006794: Transcriptional activator, Zfx/Zfy domain (domain) [64-368]
Interaction partners: - Lysine-specific demethylase phf2
- Histone lysine demethylase PHF8
- Lysine-specific demethylase 5D
- PHD finger protein 13
- Cysteine and glycine-rich protein 1b.
- SH3 domain-binding glutamic acid-rich-like protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0007389 (pattern specification process), GO:0035295 (tube development), GO:0009887 (animal organ morphogenesis), GO:0048598 (embryonic morphogenesis), GO:0048729 (tissue morphogenesis), GO:0009888 (tissue development), GO:0003002 (regionalization), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0009799 (specification of symmetry), GO:0009790 (embryo development), GO:0035239 (tube morphogenesis), GO:0009855 (determination of bilateral symmetry), GO:0060562 (epithelial tube morphogenesis), GO:0048568 (embryonic organ development), GO:0003007 (heart morphogenesis), GO:0060972 (left/right pattern formation), GO:0035050 (embryonic heart tube development), GO:0048562 (embryonic organ morphogenesis), GO:0072359 (circulatory system development), GO:0003143 (embryonic heart tube morphogenesis), GO:0002009 (morphogenesis of an epithelium), GO:0060429 (epithelium development), GO:0007507 (heart development), GO:0061371 (determination of heart left/right asymmetry), GO:0007368 (determination of left/right symmetry), GO:0001947 (heart looping)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)