wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: ATP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.93) (ATP-dependent NAD(P)HX dehydratase) (O94347)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
Subcellular location: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03157, ECO:0000269|PubMed:16823372}.
Sequence: MTSGSPKITNLLTRVKRIIPPLLDTFHKGQAGRVGVFGGCQHYTGAPYYSSMSSMLFGSDQSHIFCEKEAANVIKSYSPDLIVHPFLREKDKAGPEDSVDKCFELIKPMMGRLHAIVIGPGLGRDEWMQEIMAKVIEYARKNDMPMVIDADGLWLIQQRPELVSGYHNVILTPNVIEFKRLCDKLDIKSDGPDACNQLAGKLNLLIIQKGQSDIISDGATAYACSVPGGLKRCGGQGDILTGILATFLAWRHAYLSKEWDTEGNMDAKECLFLAAFGASACTRWCSRLAFKECGRATQSTDLVRHVGKAYNALMEDEIPSVEEKIKD
InterPro domains: - IPR017953: Carbohydrate kinase, predicted, conserved site (conserved_site) [115-125]
- IPR000631: ATP/ADP-dependent (S)-NAD(P)H-hydrate dehydratase (domain) [11-315]
- IPR029056: Ribokinase-like (homologous_superfamily) [12-314]
Interaction partners: - NAD
- Enhancer of mRNA-decapping protein 3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016835 (carbon-oxygen lyase activity), GO:0016836 (hydro-lyase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0044238 (primary metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0019637 (organophosphate metabolic process), GO:0006793 (phosphorus metabolic process), GO:0006753 (nucleoside phosphate metabolic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0072524 (pyridine-containing compound metabolic process), GO:0009117 (nucleotide metabolic process), GO:0019362 (pyridine nucleotide metabolic process), GO:0046496 (nicotinamide nucleotide metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: IQ domain-containing protein IQM1 (IQ motif-containing protein 1) (O82645)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Involved in the modulation of stomatal movement. Promotes stomatal opening. May play a role in the regulation of chitin signaling. May be involved in biotic and abiotic stress responses.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:22572939}. Nucleus {ECO:0000269|PubMed:22572939}.
Sequence: MGLEVGSLCFKLKDGGLTSRTNSFKRDDTNRHQNSPKSTMERSLSFNSWEVPKETKTDSDFEVLETKKSTPNTLNGRNCERIQIKKPTVTPPEPFVFFSPRPVTELDAAATTLQKVYKSYRTRRNLADCAVVVEELWWRTLEGAALDLSSVSFFGEEKHETAVSKWARARKRAAKVGKGLSKDEKAQKLALQHWLEAIDPRHRYGHNLHFYYDVWSASKSTQPFFYWLDIGDGKDVNLEKHPRSVLQKQCIRYLGPMEREAYEVIVEDGRLMYKQGMTLINSTEEAKSIFVLSTTRNLYVGIKKKGLFQHSSFLSGGATTAAGRLVARDGILEAIWPYSGHYLPTEDNFKEFISFLEEHNVDLTNVKRCSVNEEYSSFKSTADEEEERKEVSEEVEIPSEKEERARPVFDPVKRLSCKWTSGYGPRIGCVRDYPMELQAQALEQVSLSPRVSPANSYGPIPSPRPSPKVRVSPRLAYMGIPSPRAVKC
InterPro domains: - IPR044159: IQ domain-containing protein IQM (family) [19-468]
Interaction partners: - Calmodulin-5
- Expressed protein
- Potassium channel KAT1
- Protein phosphatase 2C and cyclic nucleotide-binding/kinase domain-containing protein
- Metalloendoproteinase 3-MMP
- Probable LRR receptor-like serine/threonine-protein kinase At4g37250
- At4g27652
- AT5g23340/MKD15_20
- Catalase-2
- At4g27654
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005516 (calmodulin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0071840 (cellular component organization or biogenesis), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009561 (megagametogenesis), GO:0050794 (regulation of cellular process), GO:0016043 (cellular component organization), GO:0009559 (embryo sac central cell differentiation), GO:0048229 (gametophyte development), GO:0030154 (cell differentiation), GO:0010119 (regulation of stomatal movement), GO:0010197 (polar nucleus fusion), GO:0006996 (organelle organization), GO:0009553 (embryo sac development), GO:0048284 (organelle fusion), GO:0006997 (nucleus organization), GO:0000741 (karyogamy)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0009507 (chloroplast), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Nucleoporin like 1 (Nucleoporin p58/p45) (Q6NUZ9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Nucleus, nuclear pore complex {ECO:0000256|ARBA:ARBA00004567}.
Sequence: MSSFNFGTTTLGTTGAPAAAGGGGFSFGAATSTPAAGTGGFSFGGFGAQTSTPAPATTSTTSTLGFGTSLFAQKPTTGFSLSTPASAAASTSGLSLGSLTTSTAASTGFSLGFGKPAASATPFSLTTTTASAPAATGLSLGSVLTSTVPQTSSTGFSLNLGAAAATSSAPASGFSFGSSLFSNPTLTGLGQSTLGGPLSLGGLVSTSVATTSAPAPSLGLGGVDFSTSSEKNTDKLSSTRPEDSKALKDENLPAPICQDVDNFQKFVKEQKQVQEEISRMSSKPILKVQEDIKMLRQLLSVCASGLQRNSLSIDKLKLETSQELKNADIALRTQKTPPGLQHENTAPSDYFRALVEQFEVQLQQYRQQIEELENHLTTQGSGSHITPQDLSMAMQKLYQTFVALAAQLQGVHENVKTLKHQYLGYRRAFLEDSTDIFESKRVAGKKWQSSPRVTTGPAPFGSVPNAAAVAMAATLTQQQQPAPGPQAPLGASFGTPFSSGIGSSMGSSSLGGFGTSNTSGFNFSNPGINASAGLTFGVSNTQTPGFGAGGPLLQLKKPPAGNKRGKR
InterPro domains: - IPR024882: Nucleoporin p58/p45/NUP49 (family) [57-564]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0001775 (cell activation), GO:0045321 (leukocyte activation), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0046649 (lymphocyte activation), GO:0030097 (hemopoiesis), GO:0042110 (T cell activation), GO:0002521 (leukocyte differentiation), GO:0030098 (lymphocyte differentiation), GO:1903131 (mononuclear cell differentiation), GO:0030217 (T cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Sugar efflux transporter (P31122)
Organism: Escherichia coli (strain K12)
Function: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites. Transports L-arabinose and to a lesser extent IPTG. Seems to contribute to the control of the arabinose regulon.
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Sequence: MTTNTVSRKVAWLRVVTLAVAAFIFNTTEFVPVGLLSDIAQSFHMQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLSFLSWSFTVLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGLPLGRIVGQYFGWRMTFFAIGIGALITLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSIYLLTVVVVTAHYTAYSYIEPFVQNIAGFSANFATALLLLLGGAGIIGSVIFGKLGNQYASALVSTAIALLLVCLALLLPAANSEIHLGVLSIFWGIAMMIIGLGMQVKVLALAPDATDVAMALFSGIFNIGIGAGALVGNQVSLHWSMSMIGYVGAVPAFAALIWSIIIFRRWPVTLEEQTQ
InterPro domains: - IPR036259: MFS transporter superfamily (homologous_superfamily) [5-386]
- IPR020846: Major facilitator superfamily domain (domain) [14-388]
- IPR050189: Major Facilitator Superfamily Efflux Transporters (family) [10-391]
- IPR023495: Sugar efflux transporter, putative (family) [1-390]
- IPR011701: Major facilitator superfamily (family) [18-350]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0015144 (carbohydrate transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0022890 (inorganic cation transmembrane transporter activity), GO:0005402 (carbohydrate:monoatomic cation symporter activity), GO:0022853 (active monoatomic ion transmembrane transporter activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0015291 (secondary active transmembrane transporter activity), GO:0005351 (carbohydrate:proton symporter activity), GO:0015293 (symporter activity), GO:0015078 (proton transmembrane transporter activity), GO:0015294 (solute:monoatomic cation symporter activity), GO:0015295 (solute:proton symporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0006810 (transport), GO:0072530 (purine-containing compound transmembrane transport), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:0015931 (nucleobase-containing compound transport), GO:1901264 (carbohydrate derivative transport), GO:0015858 (nucleoside transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: ORF128 ankyrin repeat protein (Q6TVJ2)
Organism: Orf virus (strain Goat/Texas/SA00/2000) (OV-SA00) (Orf virus-San Angelo 2000)
Function: Not known
Sequence: MDFLGAALYDYVADAENVRVDEVRRLLAAGASVEYAGEFGKTALHQYMGRSGTDPAVVRALLDAGARVDLPETCCGCTPVHLCLMSANIDVEVLRMLVHEGRVEDCGRAELASAVLKEFVVNRAFDENVTERVMHVLVSAGADVNAASVVDRTPLHVCLTGMSTHPGTIAALLRFGADVNAVDLCGMSPLAVLVRSRAATAELVRMLLDGGADTHAVDSRLDSLLHQHFQSARPRPEVVHELIRHGCSPRARNRIGNTPLHEAAKHSSCKHSLVGPLLAAGASVDARNNAGRTPLHLAAASNPRACRRLIALGADVVARSYAGVTPLAQLVADNNSALVTAALNTQPEPRAVAESLRATTPVGETACSRLCVAYVVARAPSEVLGEPERALHAAFVAECLAEVAAIHAVRCGTPPVSLLEILVAARPPRSLLSRRARRLAESRTTVYRAPLRARIAAMRHRSRLVERALRALRDCVLPREVLERVLRCLSTQDLRASGLAE
InterPro domains: - IPR036770: Ankyrin repeat-containing domain superfamily (homologous_superfamily) [11-360]
- IPR002110: Ankyrin repeat (repeat) [39-318]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0016032 (viral process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0035821 (modulation of process of another organism), GO:0044068 (modulation by symbiont of host cellular process), GO:0019048 (modulation by virus of host process), GO:0048523 (negative regulation of cellular process), GO:0044403 (biological process involved in symbiotic interaction), GO:0050794 (regulation of cellular process), GO:0051701 (biological process involved in interaction with host), GO:0031341 (regulation of cell killing), GO:0051709 (regulation of killing of cells of another organism), GO:0052040 (modulation by symbiont of host programmed cell death), GO:0019054 (modulation by virus of host cellular process), GO:0060548 (negative regulation of cell death), GO:0010941 (regulation of cell death), GO:0044003 (modulation by symbiont of host process), GO:0039526 (modulation by virus of host apoptotic process), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:0052041 (suppression by symbiont of host programmed cell death), GO:0052150 (modulation by symbiont of host apoptotic process), GO:0043066 (negative regulation of apoptotic process), GO:0042981 (regulation of apoptotic process), GO:0019050 (suppression by virus of host apoptotic process), GO:0033668 (suppression by symbiont of host apoptotic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0033643 (host cell part), GO:0043657 (host cell), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0033655 (host cell cytoplasm part), GO:0033647 (host intracellular organelle), GO:0030430 (host cell cytoplasm), GO:0033648 (host intracellular membrane-bounded organelle), GO:0044165 (host cell endoplasmic reticulum), GO:0042025 (host cell nucleus)
Protein: Candida glabrata strain CBS138 chromosome A complete sequence (Q6FXS9)
Organism: Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus)
Function: Not known
Sequence: MSTFMRQYARNMARVPVSTRLNAQRFACANYRFYSEKTNYKQADQPRLRINSSAPNFDADTSHGKINLYDYLGDSWGILFSHPADFTPVCTTEMGAFAKMKPQFDKRGVKLLGLSVEDAESHRKWIKDIEEINGIDKFGFPIIADTKRHVAFLYDMCDEEGFGNINDGSLTTVRSVYVIDPAKKIRVIFTYPSQVGRNTAEVLRVIDALQTADKHGVVTPGNWSPNDDVIIPPKVSDAEASEKFGDFKTVKSYLRYTKLK
InterPro domains: - IPR024706: Peroxiredoxin, AhpC-type (family) [43-259]
- IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [48-258]
- IPR013766: Thioredoxin domain (domain) [48-211]
- IPR019479: Peroxiredoxin, C-terminal (domain) [208-244]
- IPR045020: 1-Cys peroxiredoxin (family) [50-258]
- IPR000866: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant (domain) [51-187]
- IPR050217: Thiol-specific antioxidant peroxiredoxin (family) [41-234]
Interaction partners: - Glutathione reductase
- Protein URE2
- Glutathione hydrolase
- Glutathione synthetase
- glutathione-specific gamma-glutamylcyclotransferase
- RNA polymerase II subunit A C-terminal domain phosphatase SSU72
- Sulfiredoxin
- Candida glabrata strain CBS138 chromosome M complete sequence
- Catalase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0016209 (antioxidant activity), GO:0003824 (catalytic activity), GO:0004601 (peroxidase activity), GO:0016491 (oxidoreductase activity), GO:0016684 (oxidoreductase activity, acting on peroxide as acceptor)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0006979 (response to oxidative stress), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0034599 (cellular response to oxidative stress), GO:0062197 (cellular response to chemical stress)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062039 (biofilm matrix), GO:0062040 (fungal biofilm matrix)
Protein: ORF 37 (P88925)
Organism: Human herpesvirus 8 type M
Function: Not known
Sequence: MEATPTPADLFSEDYLVDTLDGLTVDDQQAVLASLSFSKFLKHAKVRDWCAQAKIQPSMPALRMAYNYFLFSKVGEFIGSEDVCNFFVDRVFGGVRLLDVASVYAACSQMNAHQRHHICCLVERATSSQSLNPVWDALRDGIISSSKFHWAVKQQNTSKKIFSPWPITNNHFVAGPLAFGLRCEEVVKTLLATLLHPDETNCLDYGFMQSPQNGIFGVSLDFAANVKTDTEGRLQFDPNCKVYEIKCRFKYTFAKMECDPIYAAYQRLYEAPGKLALKDFFYSISKPAVEYVGLGKLPSESDYLVAYDQEWEACPRKKRKLTPLHNLIRECILHNSTTESDVYVLTDPQDTRGQISIKARFKANLFVNVRHSYFYQVLLQSSIVEEYIGLDSGIPRLGSPKYYIATGFFRKRGYQDPVNCTIGGDALDPHVEIPTLLIVTPVYFPRGAKHRLLHQAANFWSRSAKDTFPYIKWDFSYLSANVPHSP
InterPro domains: - IPR034720: Viral alkaline exonuclease (family) [28-476]
- IPR011335: Restriction endonuclease type II-like (homologous_superfamily) [110-300]
- IPR001616: Alphaherpesvirus alkaline exonuclease (family) [17-486]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0140097 (catalytic activity, acting on DNA), GO:0004518 (nuclease activity), GO:0004536 (deoxyribonuclease activity), GO:0004527 (exonuclease activity), GO:0004520 (DNA endonuclease activity), GO:0004529 (DNA exonuclease activity), GO:0004519 (endonuclease activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0044237 (cellular metabolic process), GO:0006950 (response to stress), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0033554 (cellular response to stress), GO:0006259 (DNA metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0006974 (cellular response to DNA damage stimulus), GO:0006281 (DNA repair)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0043657 (host cell), GO:0033643 (host cell part), GO:0033646 (host intracellular part), GO:0043656 (host intracellular region), GO:0033647 (host intracellular organelle), GO:0033648 (host intracellular membrane-bounded organelle), GO:0042025 (host cell nucleus)
Protein: Laminin subunit gamma 2 (F1LRH4)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000256|ARBA:ARBA00004302}.
Sequence: MPALWLSCCLGVALLLPAAQATSRREVCDCNGKSRQCVFDQELHRQTGNGFRCLNCNDNTAGVHCERCREGFYRQRDRDRCLPCNCHSKGSLGAGCDNSGQCRCKPGVVGQRCDRCQPGFHMLTDAGCTRDQRQLDSKCDCDPAGISGPCDSGRCVCKPAVTGERCDRCRAGYYHLDRANPEGCTQCFCYGHSDSCHTSADFSVHKITSTFNQDEDGWKAVQRNWAPAKLHWSPRHQDVFSSARRSDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAYDVILEGAGLQIRAPLMPPGKTLPCGITKTYTFRLNEHPSSHWSPQLSYFEYRRLLRNLTALLIRATYGEYSTGYIDNVTLISARPVSGAPAPWVERCVCPAGYKGQFCQECASGYKRDSARLGPFGTCVPCNCQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGFFGDPFGERGPVRPCQRCQCNNNVDPSASGNCDQLTGRCLKCIYNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPVGSEPGECRSDGSCVCKPGFGGLNCAHAAALTSCPACYNQVKTQMDQFAQQLQNLEALVSKAQGGNGAVPSEELEGRMQQAEQALRDILREAQISEGAMRALSLQLAKARSQENNYKNRLDDLKMTVERIRALGSQYQNRVQDTSRLISQMRLSLAESEASLQNTNIHSSEHYVGPNGFKSLAQEAARLADSHVESANTMKQLTRETEDYSKQALSLARKALSGGGGSGVLDSSVVQGLMGKLEKTKSLTQQLSREGTQADIEADRSYQHSLRLLDSASQLQGIRDSSFQAEAKRIRQKADSLSNLVTKQMDAFTSVRNNLGNWEKETRQLLQTGKDRRQTSDQLLSRANLAKSRAQEALSMGNATFYEVENILKNLREFDLQVEDRKAEAEEAMKRLSYISQKVADASDKTQQAETALGSATADTQRAKNAATEALEITSEIEQEIGSLNLEANVTADGALAMEKGLATLKSEMREVEGELARKELEFHTDKDSLQLVITEAQQADARAKSTGVTIQDTLNTLEGILRLIDQPDAVDEEGLMLLEQELFQAKTQINSRLRPLMSELEDRARRQSNHLHLLETSIDGILADVKNLENIRDNLPPGCYNTQALEQQ
InterPro domains: - IPR050440: Laminin/Netrin Extracellular Matrix (family) [28-1078]
- IPR000034: Laminin IV (domain) [213-381]
- IPR002049: Laminin-type EGF domain (domain) [28-614]
- IPR000742: EGF-like domain (domain) [36-603]
- IPR056863: Laminin/attractin/netrin-like, EGF domain (domain) [28-75]
Interaction partners: - Laminin subunit beta-3
- Laminin subunit alpha 3
- Laminin subunit alpha-5
- Laminin subunit beta-1
- CD44 antigen
- Integrin beta-4
- Laminin subunit gamma-1
- Laminin subunit beta-2
- Integrin subunit alpha 5
- Integrin alpha-6
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0035295 (tube development), GO:0001568 (blood vessel development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0035239 (tube morphogenesis), GO:0048514 (blood vessel morphogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development), GO:0001570 (vasculogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062023 (collagen-containing extracellular matrix)