wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Collagen alpha-3(IX) chain (Q14050)
Organism: Homo sapiens (Human)
Function: Structural component of hyaline cartilage and vitreous of the eye.
Subcellular location: Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Sequence: MAGPRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVGEKSGSRSS
InterPro domains: - IPR050149: Collagen superfamily (family) [29-387]
- IPR008160: Collagen triple helix repeat (repeat) [29-608]
Interaction partners: - Collagen alpha-1
- Collagen alpha-2
- Matrilin-3
- CD44 antigen
- Platelet glycoprotein VI
- Sulfate transporter
- Cartilage intermediate layer protein 1
- Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3
- Integrin alpha-2
- Integrin alpha-3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0005488 (binding), GO:0005201 (extracellular matrix structural constituent), GO:0005515 (protein binding), GO:0030020 (extracellular matrix structural constituent conferring tensile strength)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0032502 (developmental process), GO:0007275 (multicellular organism development), GO:0048856 (anatomical structure development), GO:0048731 (system development), GO:0001501 (skeletal system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030312 (external encapsulating structure), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0031974 (membrane-enclosed lumen), GO:0012505 (endomembrane system), GO:0005576 (extracellular region), GO:0043233 (organelle lumen), GO:0005783 (endoplasmic reticulum), GO:0043229 (intracellular organelle), GO:0031012 (extracellular matrix), GO:0043227 (membrane-bounded organelle), GO:0005788 (endoplasmic reticulum lumen), GO:0043231 (intracellular membrane-bounded organelle), GO:0062023 (collagen-containing extracellular matrix), GO:0070013 (intracellular organelle lumen)
Protein: Small ribosomal subunit protein uS8A (40S ribosomal protein S22-A) (P0CT58)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
Sequence: MVRQSVLADCLNNIVNAERRGRRQVLIRPSSKVIVKFLTVMQKHGYIDEFTEIDDHRSGKIVIQLNGRINKCGVISPRFNVKLKDIEKWVNQLLPSRQVGVIVLTTSRGIMSHNEARAKDAGGKILGFFY
InterPro domains: - IPR047863: Small ribosomal subunit protein uS8, conserved site (conserved_site) [100-117]
- IPR035987: Small ribosomal subunit protein uS8 superfamily (homologous_superfamily) [4-130]
- IPR000630: Small ribosomal subunit protein uS8 (family) [1-130]
Interaction partners: - Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS15
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS3
- Small ribosomal subunit protein eS7
- Elongation factor 3
- Small ribosomal subunit protein uS14
- mRNA export factor elf1
- Small ribosomal subunit protein eS21
- Small ribosomal subunit protein eS27
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0044249 (cellular biosynthetic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:0019538 (protein metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006412 (translation), GO:0009059 (macromolecule biosynthetic process), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:0006518 (peptide metabolic process), GO:0010467 (gene expression), GO:0043043 (peptide biosynthetic process), GO:0002181 (cytoplasmic translation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Stage 0 sporulation protein J (P26497)
Organism: Bacillus subtilis (strain 168)
Function: Required for the initiation of sporulation and for normal chromosome segregation. Antagonizes sporulation inhibition by Soj. It probably interacts with a specific DNA site and other proteins involved in partitioning and cell division, and antagonizes Soj in response to cell cycle events related to chromosome partitioning.
Subcellular location: Cytoplasm, nucleoid {ECO:0000269|PubMed:18854156}.
Sequence: MAKGLGKGINALFNQVDLSEETVEEIKIADLRPNPYQPRKHFDDEALAELKESVLQHGILQPLIVRKSLKGYDIVAGERRFRAAKLAGLDTVPAIVRELSEALMREIALLENLQREDLSPLEEAQAYDSLLKHLDLTQEQLAKRLGKSRPHIANHLRLLTLPENIQQLIAEGTLSMGHGRTLLGLKNKNKLEPLVQKVIAEQLNVRQLEQLIQQLNQNVPRETKKKEPVKDAVLKERESYLQNYFGTTVNIKRQKKKGKIEIEFFSNEDLDRILELLSERES
InterPro domains: - IPR041468: ParB/Spo0J, HTH domain (domain) [116-216]
- IPR036086: ParB/Sulfiredoxin superfamily (homologous_superfamily) [24-115]
- IPR050336: Chromosome-partitioning and nucleoid occlusion protein (family) [3-280]
- IPR003115: ParB-like, N-terminal domain (domain) [21-114]
- IPR057240: ParB, C-terminal dimerisation domain (domain) [230-277]
- IPR004437: ParB/RepB/Spo0J partition protein (domain) [20-199]
Interaction partners: - Sporulation initiation inhibitor protein Soj
- Chromosomal replication initiator protein DnaA
- DNA translocase SpoIIIE
- Cell division protein FtsZ
- Chromosome-anchoring protein RacA
- Segregation and condensation protein A
- Segregation and condensation protein B
- Septum site-determining protein DivIVA
- Chromosome partition protein Smc
- DNA translocase SftA
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:1900190 (regulation of single-species biofilm formation), GO:1900192 (positive regulation of single-species biofilm formation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex)
Protein: Valacyclovir hydrolase (VACVase) (Valacyclovirase) (EC 3.1.-.-) (Biphenyl hydrolase-like protein) (Q8R164)
Organism: Mus musculus (Mouse)
Function: Serine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. Activates valacyclovir to acyclovir. May play a role in detoxification processes. It is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol (By similarity).
Subcellular location: Cytoplasm {ECO:0000250}.
Sequence: MATATVRPAAQRLRLLLSPLKSRICVPQAEPVATFGTAVTSAKVAVNGVHLHYQRVGEGEHAILLLPGMLGSGKTDFAPQLQSLNKKRFTLVAWDPRGYGYSRPPDRDFPRDFFERDAKDAVDLMKALQFKQVSLLGWSDGGITALIAAAKYPSYIRKMVIWGANAYVTEEDSRIYQGIRDVSKWSEKARKPLEALYGYDYLAKTCEDWVDGISQFKQLPEGNICRHLLPLVQCPTLIVHGEKDPLVPRFHADFLLQHVKGSRLHLMPEGKHNLHLRFADEFNRLVEDFLQ
InterPro domains: - IPR029058: Alpha/Beta hydrolase fold (homologous_superfamily) [38-290]
- IPR000073: Alpha/beta hydrolase fold-1 (domain) [62-174]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0052689 (carboxylic ester hydrolase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051716 (cellular response to stimulus), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006520 (amino acid metabolic process), GO:0006805 (xenobiotic metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0009410 (response to xenobiotic stimulus), GO:0070887 (cellular response to chemical stimulus), GO:0006082 (organic acid metabolic process), GO:0009636 (response to toxic substance), GO:0071466 (cellular response to xenobiotic stimulus), GO:0043436 (oxoacid metabolic process), GO:0019752 (carboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: GH02708p (Q8IH74)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MDPITMAKNKVLRMLEMKRAQQLKIIDSRVSAKVPRVTKLPPLKDIVKDTYCMETEDPGTEIAPLSNKLHPDYEEIIIVSASCNTDITIPPNQLSKASPRSLLKSSVLLYNISNGQDANKNMSNSLIASIQSEVARQTSNTTLSTIQSNATKVMSSADKNCQHGEDMVIMHLPKDRVRKTLVSIATQTDLQPEFPLLTLPPKRQSRERTRRNYRRRRTQGSGSNMSTSSSDFSSDCSSLVSHRSRSQYDSIDQLRNLDVAATCGGSIGNGGYSSRSTQRHRSSVSSSSYSENGQYRRRQRRTSYNKRRSRNQKRGSTSSSCSGSEKSDRERSRSPHRKLRHSRSRSRSKSDTRYPNNNSSSNNNNRRGFFDRNVSQPAVEERRIVYVGRIEQETTKEILRRKFLPYGSIKQITIHYKENGMKYGFVTYERAQDAFTAIDTSHRDSQISMYDISFGGRRAFCRSSYADLGEFFFTFYIILCTILSNLSFIDNAGINNYNSYVFPKEAPAPNVVEDSFEALLLQVKAKLNAGKSPVGSSTLEAPSASGTVLQGHSQM
InterPro domains: - IPR035979: RNA-binding domain superfamily (homologous_superfamily) [328-441]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [364-467]
- IPR034605: PGC-1 (family) [13-527]
- IPR000504: RNA recognition motif domain (domain) [383-466]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0042592 (homeostatic process), GO:0006950 (response to stress), GO:0045927 (positive regulation of growth), GO:0048871 (multicellular organismal-level homeostasis), GO:0040008 (regulation of growth), GO:0050794 (regulation of cellular process), GO:0048522 (positive regulation of cellular process), GO:0001894 (tissue homeostasis), GO:0030307 (positive regulation of cell growth), GO:0051128 (regulation of cellular component organization), GO:0006979 (response to oxidative stress), GO:0097009 (energy homeostasis), GO:0060249 (anatomical structure homeostasis), GO:0001558 (regulation of cell growth)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005654 (nucleoplasm), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0016604 (nuclear body), GO:0043229 (intracellular organelle), GO:0016607 (nuclear speck), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043231 (intracellular membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Post-GPI attachment to proteins factor 6 (EC 3.1.1.4) (GPI processing phospholipase A2) (GPI-PLA2) (Protein M83) (Transmembrane protein 6) (Transmembrane protein 8) (Transmembrane protein 8A) (Q9HCN3)
Organism: Homo sapiens (Human)
Function: Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchor proteins (GPI-AP). Has phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI. Required for the shedding of the GPI-AP TDGF1, but not CFC1, at the cell surface. Shedding of TDGF1 modulates Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells. Also indirectly involved in the translocation of RAC1 from the cytosol to the plasma membrane by maintaining the steady state amount of CAV1-enriched plasma membrane subdomains, stabilizing RAC1 at the plasma membrane. In contrast to myomaker (TMEM8C), has no fusogenic activity.
Subcellular location: Cell membrane {ECO:0000269|PubMed:27881714}; Multi-pass membrane protein {ECO:0000255}. Lysosome membrane {ECO:0000269|PubMed:21752829}; Multi-pass membrane protein {ECO:0000255}.
Sequence: MGRAGTGTGGEAVAAVVAGPLLLLLLARPPPASAGYSGKSEVGLVSEHFSQAPQRLSFYSWYGSARLFRFRVPPDAVLLRWLLQVSRESGAACTDAEITVHFRSGAPPVINPLGTSFPDDTAVQPSFQVGVPLSTTPRSNASVNVSHPAPGDWFVAAHLPPSSQKIELKGLAPTCAYVFQPELLVTRVVEISIMEPDVPLPQTLLSHPSYLKVFVPDYTRELLLELRDCVSNGSLGCPVRLTVGPVTLPSNFQKVLTCTGAPWPCRLLLPSPPWDRWLQVTAESLVGPLGTVAFSAVAALTACRPRSVTIQPLLQSSQNQSFNASSGLLSPSPDHQDLGRSGRVDRSPFCLTNYPVTREDMDVVSVHFQPLDRVSVRVCSDTPSVMRLRLNTGMDSGGSLTISLRANKTEMRNETVVVACVNAASPFLGFNTSLNCTTAFFQGYPLSLSAWSRRANLIIPYPETDNWYLSLQLMCPENAEDCEQAVVHVETTLYLVPCLNDCGPYGQCLLLRRHSYLYASCSCKAGWRGWSCTDNSTAQTVAQQRAATLLLTLSNLMFLAPIAVSVRRFFLVEASVYAYTMFFSTFYHACDQPGEAVLCILSYDTLQYCDFLGSGAAIWVTILCMARLKTVLKYVLFLLGTLVIAMSLQLDRRGMWNMLGPCLFAFVIMASMWAYRCGHRRQCYPTSWQRWAFYLLPGVSMASVGIAIYTSMMTSDNYYYTHSIWHILLAGSAALLLPPPDQPAEPWACSQKFPCHYQICKNDREELYAVT
InterPro domains: - IPR021910: NGX6/PGAP6/MYMK (family) [20-770]
- IPR000742: EGF-like domain (domain) [494-533]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0007155 (cell adhesion), GO:0050794 (regulation of cellular process), GO:0051726 (regulation of cell cycle), GO:0031589 (cell-substrate adhesion), GO:0007160 (cell-matrix adhesion), GO:0007346 (regulation of mitotic cell cycle)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0009986 (cell surface), GO:0005886 (plasma membrane)
Protein: Heat shock protein 12.6 (SHSP domain-containing protein) (G5EE36)
Organism: Caenorhabditis elegans
Function: Not known
Sequence: MMSVPVMADEGTKWDWPLQKGDGVVNVLDDDDHFEVGLEAHNFLPKEIEVKNIGELLEIHMEHNVKKDSFGDVSRNITRCYKLPKNVDMKTIKSNLDSHGILHIEARKMH
InterPro domains: - IPR001436: Alpha crystallin/Small heat shock protein, animal type (family) [14-108]
- IPR008978: HSP20-like chaperone (homologous_superfamily) [15-110]
- IPR002068: Alpha crystallin/Hsp20 domain (domain) [15-110]
Interaction partners: - Heat shock protein Hsp-16.1/Hsp-16.11
- Heat shock protein Hsp-16.48/Hsp-16.49
- Stress-induced protein 1
- Heat shock protein hsp-16.2
- Heat shock transcription factor hsf-1
- Heat shock protein Hsp-16.41
- Forkhead box protein O
- Superoxide dismutase 2, mitochondrial
- Metallothionein-1
- Heat shock protein 70
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0031072 (heat shock protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:0035966 (response to topologically incorrect protein)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: C2H2-type domain-containing protein (Q5AI92)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Not known
Sequence: MSNPNESEPHTQPEINNASHIVKPEGSQTVNTGFICRWSDCTENTYNNLTSLVNHLNSKHIAQLPPGSNTKYICYWENCARYGLDQPSRFALISHCRTHTGEKPYFCPVPECEKHFTRSDALTKHVKAVHDLHSVKDQLNLLKDKARKGQIELGVNVEDLSEEDYLRIIEQDYEIQKPWWFTNEFLDVIRAGETDKLEEHNKDDDLDKQLEALPFDLKQYQLANSRYKQFINSLTSARASNEIEDEDEVDGLIPRSDDNNSVINVVRKQLQHEKPNKKFPRVMSNPVLERLSNDTKKLAHDYIRHENDQNDDDIDKISDLETLKTLHDKLANQLNTAYKINKVLANQLTSNIKMKRKLWVYTQLLMDANIQVGLPPEATSAPQRVMQDEYDEELLRG
InterPro domains: - IPR056436: ZIC1-5/GLI1-3like, C2H2 zinc finger (domain) [74-103]
- IPR013087: Zinc finger C2H2-type (domain) [34-130]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [90-130]
- IPR050329: GLI C2H2-type zinc-finger (family) [19-130]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0006357 (regulation of transcription by RNA polymerase II)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: EPM2A glucan phosphatase, laforin (H0Y7S8)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: GHWIEATGHTNEMKHTTDFYFNIAGHQAMHYSRILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFQTEWDIVQNSSGCNRYPEPMTPDTMIKLYREEGLAYIWMPTPDMSTEDEKRTADMCCSGMWEETADFGLGILDYLKQK
InterPro domains: - IPR029021: Protein-tyrosine phosphatase-like (homologous_superfamily) [11-132]
- IPR042942: Laforin (family) [1-115]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0006793 (phosphorus metabolic process), GO:0036211 (protein modification process), GO:0006796 (phosphate-containing compound metabolic process), GO:0043412 (macromolecule modification), GO:0016311 (dephosphorylation), GO:0006470 (protein dephosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)