Protein: N-acetyldiaminopimelate deacetylase (EC 3.5.1.47) (O34916)
Organism: Bacillus subtilis (strain 168)
Function: Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
Sequence: MKIEELIAIRRDLHRIPELGFQEFKTQQYLLNVLEQYPQDRIEIEKWRTGLFVKVNGTAPEKMLAYRADIDALSIEEQTGLPFASEHHGNMHACGHDLHMTIALGIIDHFVHHPVKHDLLFLFQPAEEGPGGAEPMLESDVLKKWQPDFITALHIAPELPVGTIATKSGLLFANTSELVIDLEGKGGHAAYPHLAEDMVVAASTLVTQLQTIISRNTDPLDSAVITVGTITGGSAQNIIAETAHLEGTIRTLSEESMKQVKERIEDVVKGIEIGFRCKGKVTYPSVYHQVYNTSGLTEEFMSFVAEHQLATVIEAKEAMTGEDFGYMLKKYPGFMFWLGADSEHGLHHAKLNPDENAIETAVHVMTGYFSVYAN
InterPro domains: - IPR002933: Peptidase M20 (family) [66-367]
- IPR011650: Peptidase M20, dimerisation domain (domain) [179-269]
- IPR023905: Acetyldiaminopimelate deacetylase (family) [3-372]
- IPR017439: Amidohydrolase (family) [1-374]
- IPR036264: Bacterial exopeptidase dimerisation domain (homologous_superfamily) [178-282]
Interaction partners: - Diaminopimelate epimerase
- 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase
- Putative dipeptidase YtjP
- Probable N-acetyl-LL-diaminopimelate aminotransferase
- 4-hydroxy-tetrahydrodipicolinate reductase
- Diaminopimelate decarboxylase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0019213 (deacetylase activity), GO:0016811 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901576 (organic substance biosynthetic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0006082 (organic acid metabolic process), GO:0044249 (cellular biosynthetic process), GO:0006520 (amino acid metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0043436 (oxoacid metabolic process), GO:0016053 (organic acid biosynthetic process), GO:0008652 (amino acid biosynthetic process), GO:1901605 (alpha-amino acid metabolic process), GO:0019752 (carboxylic acid metabolic process), GO:1901607 (alpha-amino acid biosynthetic process), GO:0009066 (aspartate family amino acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process), GO:0006553 (lysine metabolic process), GO:0043650 (dicarboxylic acid biosynthetic process), GO:0009067 (aspartate family amino acid biosynthetic process), GO:0043648 (dicarboxylic acid metabolic process), GO:0009085 (lysine biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)