wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Rifin (Q9NFB3)
Organism: Plasmodium falciparum (isolate 3D7)
Function: Not known
Sequence: MKIHYTNILLFPLKLNILVNTHKKPSITSRHIQTTRLLCECELYTPNYDNDPEMKSVMQQFHDRTTQRFHEYDENLKEKRQKCKDKCDKEIQKIILKDKIEKELTEKFSSLQTDIHSDAIPTCICEKSLADKVEKNCLKCTQNLGKIVAPSSGVLAGISEAALSVWKTTEIAAAMELAKQAGAAAGLKAGHLAGTNAVIEQLRTLGIYFVGDKLLETIIDVTNYMNVSFIYDKVYSHYTTSCTPSLVNDQLVGTFNTSDPFCNLVHSNLQGSFYRSSAQTIIYEKVEEAVAGAEQAATTKTAVMTPIYTTEFTAKNIAEVEAATTSYYTPIIASIVAIVIIVLIMVIIYLILRYRRKMKLKKKLQYIKLLEE
InterPro domains: - IPR006373: Variant surface antigen Rifin (family) [1-372]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0046812 (host cell surface binding), GO:0046789 (host cell surface receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response), GO:0042783 (evasion of host immune response), GO:0020033 (antigenic variation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0018995 (host cellular component), GO:0033643 (host cell part), GO:0043657 (host cell), GO:0033644 (host cell membrane), GO:0020002 (host cell plasma membrane)
Protein: Protein Flattop (Cilia- and flagella-associated protein 126) (Q3SZT6)
Organism: Bos taurus (Bovine)
Function: Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear.
Subcellular location: Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q6P8X9}. Cell projection, cilium {ECO:0000250|UniProtKB:Q6P8X9}. Apical cell membrane {ECO:0000250|UniProtKB:Q6P8X9}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:34715025}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q6P8X9}. Note=Localizes to the apical cell membrane, the basal body and the primary cilium in monociliated node cells (By similarity). {ECO:0000250|UniProtKB:Q6P8X9, ECO:0000269|PubMed:34715025}.
Sequence: MATNYSANQYEKPFSPKYLQNWSLAKPTKERISSHEGYTQIIANDRGHLLPSVPRSKASPWGSFMGTWQMPLKVPPARATLTSRTAAGAASLTRWIQKNPDLLKASNGLRPEIFGKPHDPDSQKKLRKSITKTVQQAPSPTIIPSSPASNLSSPDQLQSSHPSAGHTPGPQSPLNSPKCPPGSPCLPHAGRNLAEV
InterPro domains: - IPR038797: Protein Flattop (family) [1-190]
Interaction partners: - Tektin-1
- Tektin-4
- Cilia and flagella associated protein 45.
- Outer dynein arm-docking complex subunit 1
- EF-hand domain-containing protein 1
- Cilia- and flagella-associated protein 276
- Sperm-associated antigen 8
- Tektin-3
- Cilia- and flagella-associated protein 52
- Cilia- and flagella- associated protein 210
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006996 (organelle organization), GO:0030030 (cell projection organization), GO:0044782 (cilium organization), GO:0120036 (plasma membrane bounded cell projection organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0005930 (axoneme), GO:0005737 (cytoplasm), GO:0099080 (supramolecular complex), GO:0099081 (supramolecular polymer), GO:0005879 (axonemal microtubule), GO:0005881 (cytoplasmic microtubule), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0099568 (cytoplasmic region), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0099512 (supramolecular fiber), GO:0005929 (cilium), GO:0032838 (plasma membrane bounded cell projection cytoplasm), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0005856 (cytoskeleton), GO:0099513 (polymeric cytoskeletal fiber), GO:0097014 (ciliary plasm), GO:0005874 (microtubule), GO:0015630 (microtubule cytoskeleton)
Protein: C-C motif chemokine 28 (Mucosae-associated epithelial chemokine) (MEC) (Protein CCK1) (Small-inducible cytokine A28) (Q9NRJ3)
Organism: Homo sapiens (Human)
Function: Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner.
Subcellular location: Secreted.
Sequence: MQQRGLAIVALAVCAALHASEAILPIASSCCTEVSHHISRRLLERVNMCRIQRADGDCDLAAVILHVKRRRICVSPHNHTVKQWMKVQAAKKNGKGNVCHRKKHHGKRNSNRAHQGKHETYGHKTPY
InterPro domains: - IPR039809: Chemokine beta/gamma/delta (family) [9-88]
- IPR000827: CC chemokine, conserved site (conserved_site) [30-74]
- IPR036048: Chemokine interleukin-8-like superfamily (homologous_superfamily) [24-116]
- IPR001811: Chemokine interleukin-8-like domain (domain) [28-86]
Interaction partners: - C-C motif chemokine 13
- Stromal cell-derived factor 1
- C-C motif chemokine 21
- C-C motif chemokine 5
- Platelet factor 4
- C-X-C motif chemokine 13
- Platelet basic protein
- C-X-C motif chemokine 9
- C-X-C motif chemokine 2
- C-X-C motif chemokine 10
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (signaling receptor activator activity), GO:0005126 (cytokine receptor binding), GO:0048018 (receptor ligand activity), GO:0001664 (G protein-coupled receptor binding), GO:0005125 (cytokine activity), GO:0042379 (chemokine receptor binding), GO:0008009 (chemokine activity)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0065008 (regulation of biological quality), GO:0048870 (cell motility), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0042330 (taxis), GO:0051707 (response to other organism), GO:0006955 (immune response), GO:0009607 (response to biotic stimulus), GO:0006952 (defense response), GO:0043207 (response to external biotic stimulus), GO:0006935 (chemotaxis), GO:0007204 (positive regulation of cytosolic calcium ion concentration), GO:0070887 (cellular response to chemical stimulus), GO:0006959 (humoral immune response), GO:0098542 (defense response to other organism), GO:0016477 (cell migration), GO:0060326 (cell chemotaxis), GO:0019730 (antimicrobial humoral response), GO:0061844 (antimicrobial humoral immune response mediated by antimicrobial peptide)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region)
Protein: Dystroglycan 1 (C9JEN1)
Organism: Homo sapiens (Human)
Function: Not known
Subcellular location: Cell membrane, sarcolemma {ECO:0000256|ARBA:ARBA00004135}.
Sequence: MRMSVGLSLLLPLSGRTFLLLLSVVMAQSHWPSEPSEAVRDWENQLEASMHSVLSDLHEAVPTVVGIPDGTAVVGRSFRVTIPTDLIASSGDIIKVSAAGKEALPSWLHWDSQSHTLEGLPLDTDKGVHYISVS
InterPro domains: - IPR006644: Dystroglycan-type cadherin-like (domain) [62-134]
- IPR015919: Cadherin-like superfamily (homologous_superfamily) [62-133]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [52-134]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhesion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Collagen and calcium-binding EGF domain-containing protein 1 (Full of fluid protein) (A8WGB1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis. Necessary for lymphangiogenesis, but is probably not part of either the vegfc-vegfr3 signaling or sox18-prox1 transcriptional pathways.
Subcellular location: Secreted {ECO:0000305}.
Sequence: MIYPGRGASLSVAVALVLFSSGAPWTFREEKEDVDREVCSESKIATTKYPCVKSTGEVTTCYRKKCCEGFKFVLGQCIPEDYDVCAGAPCEQQCTDHFGRVVCTCYDGYRYDRERHRNREKPYCLDIDECANNNETVCSQMCVNTPGSYRCDCHSGFYLEDDGKTCTKGERAPLFEKSDNVMKEGTCSATCEDFHQMKMTVLQLKQKMSLLSSNTEINKQMTNEKMMMTTNSFLPGPPGPPGPAGTPGAKGSSGSPGQMGPPGLPGPRGDMGPIGPSPDLSHIKQGRRGPVGPPGAPGRDGMKGERGFPGPSGPPGPPGSFDFLLLMMADIRNDIAELQSKVFSRPLHSSFEDFPSAPDSWRDTPENLDFGSGEDYKSQSPPKSSRKRKLPRNLKNPDWPV
InterPro domains: - IPR008160: Collagen triple helix repeat (repeat) [236-275]
- IPR001881: EGF-like calcium-binding domain (domain) [81-167]
- IPR018097: EGF-like calcium-binding, conserved site (conserved_site) [126-151]
- IPR000152: EGF-type aspartate/asparagine hydroxylation site (ptm) [142-153]
- IPR000742: EGF-like domain (domain) [84-167]
Interaction partners: - Vascular endothelial growth factor C
- ADAM metallopeptidase with thrombospondin type 1 motif, 3.
- Vascular endothelial growth factor receptor 3
- C-fos induced growth factor
- SRY-box transcription factor 18
- Lymphatic vessel endothelial hyaluronic receptor 1b
- ADAM metallopeptidase with thrombospondin type 1 motif, 14.
- Prospero homeobox 1a
- Epidermal growth factor.
- Integrin alpha-9
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0005509 (calcium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0003206 (cardiac chamber morphogenesis), GO:0003170 (heart valve development), GO:0009887 (animal organ morphogenesis), GO:0048513 (animal organ development), GO:0061383 (trabecula morphogenesis), GO:0003205 (cardiac chamber development), GO:0060343 (trabecula formation), GO:0048731 (system development), GO:0003171 (atrioventricular valve development), GO:0003007 (heart morphogenesis), GO:0061384 (heart trabecula morphogenesis), GO:0072359 (circulatory system development), GO:0007507 (heart development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure)
Protein: Insulin growth factor-like family member (Q6B9Z0)
Organism: Mus musculus (Mouse)
Function: Probable ligand of the IGFLR1 cell membrane receptor.
Subcellular location: Secreted {ECO:0000269|PubMed:21454693}.
Sequence: MKIRNACAVLIEVLLFILEGVTGARKISTFSGPGSWPCNPKCDGRTYNPSEECCVHDTILPFKRINLCGPSCTYRPCFELCCPESYSPKKKFIVKLKVHGERSHCSSSPISRNCKSNKIFHGEDIEDNQLSLRKKSGDQP
InterPro domains: - IPR032744: Insulin growth factor-like family (family) [2-120]
Interaction partners: - IGF-like family receptor 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0050793 (regulation of developmental process), GO:0023057 (negative regulation of signaling), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulation of signaling), GO:0051241 (negative regulation of multicellular organismal process), GO:0051239 (regulation of multicellular organismal process), GO:0051093 (negative regulation of developmental process), GO:0048523 (negative regulation of cellular process), GO:0048585 (negative regulation of response to stimulus), GO:0090287 (regulation of cellular response to growth factor stimulus), GO:0009968 (negative regulation of signal transduction), GO:0010648 (negative regulation of cell communication), GO:2000026 (regulation of multicellular organismal development), GO:0010646 (regulation of cell communication), GO:0009966 (regulation of signal transduction), GO:0070168 (negative regulation of biomineral tissue development), GO:0070167 (regulation of biomineral tissue development), GO:0090101 (negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway), GO:0090092 (regulation of transmembrane receptor protein serine/threonine kinase signaling pathway), GO:1903844 (regulation of cellular response to transforming growth factor beta stimulus), GO:0030512 (negative regulation of transforming growth factor beta receptor signaling pathway), GO:0017015 (regulation of transforming growth factor beta receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Ras-related protein RABC2a (AtRABC2a) (Ras-related protein Rab18B) (AtRab18B) (O49841)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Intracellular vesicle trafficking and protein transport.
Subcellular location: Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:18703495}. Note=Colocalizes with peroxisome.
Sequence: MGSSSGQSGYDLSFKILLIGDSGVGKSSLLVSFISSSVEDLAPTIGVDFKIKQLTVGGKRLKLTIWDTAGQERFRTLTSSYYRGAQGIILVYDVTRRETFTNLVDVWGKEIELYSTNQECVRMLVGNKVDRESERGVSREEGIALAKELNCMFLECSARTRQNVEQCFEELALKIMEVPSLLEEGSSAVKRNILKQKPEHQTNTQSGCCS
InterPro domains: - IPR050227: Ras-related protein Rab (family) [14-209]
- IPR005225: Small GTP-binding domain (domain) [14-170]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [7-209]
- IPR001806: Small GTPase (family) [6-210]
- IPR025662: Sigma-54 interaction domain, ATP-binding site 1 (binding_site) [16-29]
Interaction partners: - Myosin-6
- Geranylgeranyl transferase type-2 subunit beta 1
- At3g14910
- Myosin-17
- Rab escort protein 1
- Rab3 GTPase-activating protein catalytic subunit
- Rab3 GTPase-activating protein catalytic subunit
- Myosin-13
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0071840 (cellular component organization or biogenesis), GO:0071554 (cell wall organization or biogenesis), GO:0051649 (establishment of localization in cell), GO:0044085 (cellular component biogenesis), GO:0046907 (intracellular transport), GO:0051668 (localization within membrane), GO:0042546 (cell wall biogenesis), GO:0006810 (transport), GO:0016192 (vesicle-mediated transport), GO:0016197 (endosomal transport), GO:0098876 (vesicle-mediated transport to the plasma membrane), GO:0032456 (endocytic recycling)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005794 (Golgi apparatus), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Sulfotransferase (EC 2.8.2.-) (Q6DHH8)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Sequence: MEQEPLSYEEAITRAADAIQRFPLKDVQGVPLMSTIADNWKSISEFCPDPSDLLISTYPKAGTTWTQEIVDLLLNNGDAQVCKRAPTAVRIPFLEICAPPPIPSGLELLKQMKPPRVIKTHLPIQLVPVGFWQNKCKVIYMARNAKDNLVSYFHFDRMNLTQPEPGPWDGYIHKFMKGQLGWGSWYDHVKGYWKESKERNILYILYEDMKENPSREIKRIMHYLDLSVSEDVINKIVQLTSFHVMKDNPMANYSYIPKAVFDQSISAFMRKGEVGDWVNHFTPAQSKMFDEDYTNQMKDVDIPFRLNI
InterPro domains: - IPR000863: Sulfotransferase domain (domain) [50-300]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [13-308]
Interaction partners: - Progestin and adipoQ receptor family member 4
- ADP-ribosylarginine hydrolase
- Serine/threonine-protein phosphatase
- Protein pelota homolog
- Mid1-interacting protein 1A
- Mitochondrial tRNA translation optimization 1
- Calcium-transporting ATPase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016782 (transferase activity, transferring sulphur-containing groups), GO:0008146 (sulfotransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0051716 (cellular response to stimulus), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0009410 (response to xenobiotic stimulus), GO:0070887 (cellular response to chemical stimulus), GO:0006805 (xenobiotic metabolic process), GO:0071466 (cellular response to xenobiotic stimulus)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Prostamide/prostaglandin F synthase (Prostamide/PG F synthase) (Prostamide/PGF synthase) (EC 1.11.1.20) (Peroxiredoxin-like 2B) (Protein FAM213B) (Q8TBF2)
Organism: Homo sapiens (Human)
Function: Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor. Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha) (By similarity).
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9DB60}.
Sequence: MSTVDLARVGACILKHAVTGEAVELRSLWREHACVVAGLRRFGCVVCRWIAQDLSSLAGLLDQHGVRLVGVGPEALGLQEFLDGDYFAGELYLDESKQLYKELGFKRYNSLSILPAALGKPVRDVAAKAKAVGIQGNLSGDLLQSGGLLVVSKGGDKVLLHFVQKSPGDYVPKEHILQVLGISAEVCASDPPQCDREV
InterPro domains: - IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [17-110]
- IPR032801: Peroxiredoxin-like 2A/B/C (family) [20-179]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016209 (antioxidant activity), GO:0004601 (peroxidase activity), GO:0005515 (protein binding), GO:0016491 (oxidoreductase activity), GO:0016684 (oxidoreductase activity, acting on peroxide as acceptor), GO:0051920 (peroxiredoxin activity), GO:0140824 (thioredoxin-dependent peroxiredoxin activity), GO:0008379 (thioredoxin peroxidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0044249 (cellular biosynthetic process), GO:1901576 (organic substance biosynthetic process), GO:0006629 (lipid metabolic process), GO:0044283 (small molecule biosynthetic process), GO:0006082 (organic acid metabolic process), GO:0006631 (fatty acid metabolic process), GO:0043436 (oxoacid metabolic process), GO:0016053 (organic acid biosynthetic process), GO:0008610 (lipid biosynthetic process), GO:0006633 (fatty acid biosynthetic process), GO:0019752 (carboxylic acid metabolic process), GO:0033559 (unsaturated fatty acid metabolic process), GO:0046394 (carboxylic acid biosynthetic process), GO:0046456 (icosanoid biosynthetic process), GO:0072330 (monocarboxylic acid biosynthetic process), GO:0006636 (unsaturated fatty acid biosynthetic process), GO:0006692 (prostanoid metabolic process), GO:0032787 (monocarboxylic acid metabolic process), GO:0006690 (icosanoid metabolic process), GO:0006693 (prostaglandin metabolic process), GO:0046457 (prostanoid biosynthetic process), GO:0001516 (prostaglandin biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)