Protein: Homeobox-leucine zipper protein ATHB-14 (HD-ZIP protein ATHB-14) (Homeodomain transcription factor ATHB-14) (Protein PHABULOSA) (O04291)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Probable transcription factor involved in the determination of adaxial-abaxial polarity in ovule primordium. Specifies adaxial leaf fates.
Subcellular location: Nucleus {ECO:0000305}.
Sequence: MMMVHSMSRDMMNRESPDKGLDSGKYVRYTPEQVEALERVYTECPKPSSLRRQQLIRECPILSNIEPKQIKVWFQNRRCREKQRKEAARLQTVNRKLNAMNKLLMEENDRLQKQVSNLVYENGHMKHQLHTASGTTTDNSCESVVVSGQQHQQQNPNPQHQQRDANNPAGLLSIAEEALAEFLSKATGTAVDWVQMIGMKPGPDSIGIVAISRNCSGIAARACGLVSLEPMKVAEILKDRPSWLRDCRSVDTLSVIPAGNGGTIELIYTQMYAPTTLAAARDFWTLRYSTCLEDGSYVVCERSLTSATGGPTGPPSSNFVRAEMKPSGFLIRPCDGGGSILHIVDHVDLDAWSVPEVMRPLYESSKILAQKMTVAALRHVRQIAQETSGEVQYGGGRQPAVLRTFSQRLCRGFNDAVNGFVDDGWSPMGSDGAEDVTVMINLSPGKFGGSQYGNSFLPSFGSGVLCAKASMLLQNVPPAVLVRFLREHRSEWADYGVDAYAAASLRASPFAVPCARAGGFPSNQVILPLAQTVEHEESLEVVRLEGHAYSPEDMGLARDMYLLQLCSGVDENVVGGCAQLVFAPIDESFADDAPLLPSGFRIIPLEQKSTPNGASANRTLDLASALEGSTRQAGEADPNGCNFRSVLTIAFQFTFDNHSRDSVASMARQYVRSIVGSIQRVALAIAPRPGSNISPISVPTSPEALTLVRWISRSYSLHTGADLFGSDSQTSGDTLLHQLWNHSDAILCCSLKTNASPVFTFANQTGLDMLETTLVALQDIMLDKTLDEPGRKALCSEFPKIMQQGYAHLPAGVCASSMGRMVSYEQATVWKVLEDDESNHCLAFMFVNWSFV
InterPro domains: - IPR001356: Homeodomain (domain) [20-88]
- IPR013978: MEKHLA (domain) [706-851]
- IPR023393: START-like domain superfamily (homologous_superfamily) [176-388]
- IPR002913: START domain (domain) [164-392]
- IPR009057: Homedomain-like superfamily (homologous_superfamily) [24-88]
- IPR044830: Class III homeodomain-leucine zipper family (family) [15-852]
Interaction partners: - Protein LITTLE ZIPPER 3
- Probable transcription factor KAN2
- Transcription repressor KAN1
- Prohibitin-6, mitochondrial
- Probable transcription factor KAN3
- Axial regulator YABBY 1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0048532 (anatomical structure arrangement), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0010014 (meristem initiation), GO:0007389 (pattern specification process), GO:0003006 (developmental process involved in reproduction), GO:0009791 (post-embryonic development), GO:0048316 (seed development), GO:0048508 (embryonic meristem development), GO:0099402 (plant organ development), GO:0009798 (axis specification), GO:0009888 (tissue development), GO:0003002 (regionalization), GO:0009933 (meristem structural organization), GO:0090567 (reproductive shoot system development), GO:0065001 (specification of axis polarity), GO:0048731 (system development), GO:0048481 (plant ovule development), GO:0010016 (shoot system morphogenesis), GO:0009799 (specification of symmetry), GO:0009790 (embryo development), GO:0048608 (reproductive structure development), GO:0048437 (floral organ development), GO:0009793 (embryo development ending in seed dormancy), GO:0048438 (floral whorl development), GO:0009880 (embryonic pattern specification), GO:0090421 (embryonic meristem initiation), GO:0009855 (determination of bilateral symmetry), GO:0048367 (shoot system development), GO:0061458 (reproductive system development), GO:0048507 (meristem development), GO:0009943 (adaxial/abaxial axis specification), GO:0009944 (polarity specification of adaxial/abaxial axis), GO:0048827 (phyllome development), GO:0048467 (gynoecium development), GO:0009955 (adaxial/abaxial pattern specification), GO:0035670 (plant-type ovary development), GO:0048440 (carpel development), GO:0010154 (fruit development), GO:0009908 (flower development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)