wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Amphiphysin (Q6P960)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Sequence: MAEIKTGIFAKNVQKRINRAQEKVLQKLGKADETKDEQFEQCVQNFKRQEFEGSRLQREMKAYIAAVKGMQQASMNLTESLHEVYEPDWHGKDDVMTIGKNCDALWEDFHQKLVDSTINTLETYLTQFPDLKVRVAKRSRKLIDYDSARHHLETLQTSTMRNEKRIAKAEEDLKKAQRVFDDLNVGLQDELPTLWDSRVGFYVSTFKNVSSLEARFHREISFLCHKLYEVMNKLAEQHSDKMFTIQGAPSDSGPLRLARTPSPPDDESPDSSPAASPNHTLRPTSPGPPRPKSPSQLKMGPPKPPPPKVTPTRELQQEQIIDLFDGGFPEISVTSPQPNERPGESLLDLDFDPFKPDTSTPIGQTQSPVSQTLPWDLWTGDAAQPAQPATDAGFTANWAADFGSSATTVTDESANTQPAADGQGWPPADGWPTDSTPQPQGETATDEDATVPTFMADFDKMPEAEAEAPEGDVAEGEGEASPASEPEGGEGPVTTPPTDTQPEEITASSPPAETPTSTVESPVSAEPEAAEQAELPVEDIEKEQLSEESPDSVPVQETEKESPTEAALASVEDKESPIEETPTTDAKPEEETSSLEARPGDEPDNVEPKPTDEPDKVETQPGEVPDNIEPKPGDAPDNVEPQPGDETSKEGAANNGNEEEKMPIPSVVIEPASSNEGDDDRDGDITSPIATGDNGMIADCQTTKDSSGMPPRFLFKVETMHDFEAANPDELELKKGDIVLVVPTELAEDQDAGWLTGIRESDWQQRGASAKKGLFPENFTQRLE
InterPro domains: - IPR027267: AH/BAR domain superfamily (homologous_superfamily) [5-241]
- IPR036028: SH3-like domain superfamily (homologous_superfamily) [708-783]
- IPR035470: Amphiphysin I, SH3 domain (domain) [713-783]
- IPR001452: SH3 domain (domain) [712-784]
- IPR003017: Amphiphysin, isoform 1 (family) [3-258]
- IPR003005: Amphiphysin (family) [1-470]
- IPR004148: BAR domain (domain) [12-240]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0003008 (system process), GO:0003012 (muscle system process), GO:0003013 (circulatory system process), GO:0003015 (heart process), GO:0008015 (blood circulation), GO:0006936 (muscle contraction), GO:0006941 (striated muscle contraction), GO:0060047 (heart contraction), GO:0060048 (cardiac muscle contraction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)
Protein: Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Q8WVL7)
Organism: Homo sapiens (Human)
Function: Induces HBG1 expression. May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF-kappaB pathway (By similarity).
Subcellular location: Nucleus {ECO:0000250|UniProtKB:Q8VE42}.
Sequence: MEKEKGNDDGIPDQENSLDFSEHFNQLELLETHGHLIPTGTQSLWVGNSDEDEEQDDKNEEWYRLQEKKMEKDPSRLLLWAAEKNRLTTVRRLLSEKATHVNTRDEDEYTPLHRAAYSGHLDIVQELIAQGADVHAVTVDGWTPLHSACKWNNTRVASFLLQHDADINAQTKGLLTPLHLAAGNRDSKDTLELLLMNRYVKPGLKNNLEETAFDIARRTSIYHYLFEIVEGCTNSSPQS
InterPro domains: - IPR036770: Ankyrin repeat-containing domain superfamily (homologous_superfamily) [44-237]
- IPR002110: Ankyrin repeat (repeat) [73-206]
Interaction partners: - tRNA dimethylallyltransferase
- FK506-binding protein-like
- Casein kinase I isoform epsilon
- Casein kinase I isoform delta
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050793 (regulation of developmental process), GO:0051239 (regulation of multicellular organismal process), GO:2000026 (regulation of multicellular organismal development), GO:0022603 (regulation of anatomical structure morphogenesis), GO:1901342 (regulation of vasculature development), GO:0045765 (regulation of angiogenesis), GO:1903670 (regulation of sprouting angiogenesis)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0030496 (midbody), GO:0016020 (membrane), GO:0005829 (cytosol), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: P2X purinoceptor (Q7SZM1)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Endomembrane system {ECO:0000256|ARBA:ARBA00004308}. Membrane {ECO:0000256|RuleBase:RU000681}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU000681}.
Sequence: MARRCSNPLLYLFNYTTVRYVVTQNKIVGLLYRFFQLIIMCYLIGWVFVTKKGYQVVDDTIESSVVTKVKGIARVNTTFSDLWGPEEYVIPDHGGKFLFVVTNFIETPNQTLTTCPESPSVPFSTCTHDDNCTEGEAVRAGNGIKTGTCRKTDGNETNTCEIYGWCPTEKPRREAATMLREAENFTVYIRNFIKFSQFNLSKTNILKEGYPSYIKTCLHDEIHHPYCPVFRLGDIVSKAGYRFEEVAAKGGSIGIVIKWSCDFDMDTSDCHPQYSFMSMGSSTPVTAGYNFRFARYSSDAAGRTHRNLYKVYGFQLNVMVFGTASQFSIIHTIINVASVLTLMAVGSYICDVILLFMVKKKYAKFESLIKADKEIALQKMPDHSKRKFSH
InterPro domains: - IPR001429: P2X purinoreceptor (family) [1-389]
- IPR027309: P2X purinoreceptor extracellular domain superfamily (homologous_superfamily) [58-339]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0015267 (channel activity), GO:0008324 (monoatomic cation transmembrane transporter activity), GO:0005261 (monoatomic cation channel activity), GO:0022839 (monoatomic ion gated channel activity), GO:0022836 (gated channel activity), GO:0099094 (ligand-gated monoatomic cation channel activity), GO:0022834 (ligand-gated channel activity), GO:0015276 (ligand-gated monoatomic ion channel activity), GO:0035381 (ATP-gated ion channel activity), GO:0004931 (extracellularly ATP-gated monoatomic cation channel activity), GO:0005230 (extracellular ligand-gated monoatomic ion channel activity), GO:0005231 (excitatory extracellular ligand-gated monoatomic ion channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0006810 (transport), GO:0006811 (monoatomic ion transport), GO:0006812 (monoatomic cation transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0098796 (membrane protein complex), GO:1990351 (transporter complex), GO:0098797 (plasma membrane protein complex), GO:1902495 (transmembrane transporter complex), GO:0005886 (plasma membrane), GO:0034702 (ion channel complex)
Protein: Chorion protein S36 (P07182)
Organism: Drosophila melanogaster (Fruit fly)
Function: Chorion membrane (egg shell) protein; plays a role in protecting the egg from the environment.
Subcellular location: Secreted.
Sequence: MQLGLWFGILAIAATPLVSANYGPAGGHGHGHGHGQYLSGPNAGLEEYVNVASGGNQQAANQIASQAEIQPTPEEARRLGRVQAQLQALNADPNYQKLKNSEDIAESLAETNLASNIRQGKIKVVSPQFVDQHLFRSLLVPSGHNNHQVIATQPLPPIIVHQPGAPPAHVNSGPPTVVRGNPVIYKIKPSVIYQQEVINKVPTPLSLNPVYVKVYKPGKKIEAPLAPVVAPVYSQPREYSQPQGYGSAGAASSAAGAASSADGNAYGNEAPLYNSPAPYGQPNY
InterPro domains: - IPR008449: Chorion S36/S38 (family) [3-262]
Interaction partners: - Chorion protein S19
- FI16876p1
- Chorion protein S38
- Chorion protein S16
- Vitelline membrane protein Vm34Ca
- Chorion protein c at 7F
- Uncharacterized protein
- Chorion protein S18
- Chorion protein S15
- Chorion protein a at 7F, isoform A
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0005488 (binding), GO:0005201 (extracellular matrix structural constituent), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0000003 (reproduction), GO:0019953 (sexual reproduction)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix)
Protein: Uncharacterized membrane protein YhhN (P0ADI9)
Organism: Escherichia coli (strain K12)
Function: Not known
Subcellular location: Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Sequence: MLWSFIAVCLSAWLSVDASYRGPTWQRWVFKPLTLLLLLLLAWQAPMFDAISYLVLAGLCASLLGDALTLLPRQRLMYAIGAFFLSHLLYTIYFASQMTLSFFWPLPLVLLVLGALLLAIIWTRLEEYRWPICTFIGMTLVMVWLAGELWFFRPTAPALSAFVGASLLFISNFVWLGSHYRRRFRADNAIAAACYFAGHFLIVRSLYL
InterPro domains: - IPR012506: Lysoplasmalogenase-like (family) [2-206]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0016298 (lipase activity), GO:0052689 (carboxylic ester hydrolase activity), GO:0004623 (phospholipase A2 activity), GO:0004620 (phospholipase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0044255 (cellular lipid metabolic process), GO:0006629 (lipid metabolic process), GO:0044282 (small molecule catabolic process), GO:1901575 (organic substance catabolic process), GO:0044248 (cellular catabolic process), GO:0006082 (organic acid metabolic process), GO:0030258 (lipid modification), GO:0006631 (fatty acid metabolic process), GO:0016054 (organic acid catabolic process), GO:0044242 (cellular lipid catabolic process), GO:0043436 (oxoacid metabolic process), GO:0016042 (lipid catabolic process), GO:0019752 (carboxylic acid metabolic process), GO:0046395 (carboxylic acid catabolic process), GO:0034440 (lipid oxidation), GO:0019395 (fatty acid oxidation), GO:0009062 (fatty acid catabolic process), GO:0072329 (monocarboxylic acid catabolic process), GO:0006635 (fatty acid beta-oxidation), GO:0032787 (monocarboxylic acid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Phenylacetic acid degradation protein PaaY (P77181)
Organism: Escherichia coli (strain K12)
Function: Not known
Sequence: MPIYQIDGLTPVVPEESFVHPTAVLIGDVILGKGVYVGPNASLRGDFGRIVVKDGANIQDNCVMHGFPEQDTVVGEDGHIGHSAILHGCIIRRNALVGMNAVVMDGAVIGENSIVGASAFVKAKAEMPANYLIVGSPAKAIRELSEQELAWKKQGTHEYQVLVTRCKQTLHQVEPLREIEPGRKRLVFDENLRPKQ
InterPro domains: - IPR011004: Trimeric LpxA-like superfamily (homologous_superfamily) [2-168]
- IPR001451: Hexapeptide repeat (repeat) [88-122]
- IPR011974: Phenylacetic acid degradation protein PaaY (family) [3-195]
- IPR050484: Transferase Hexapeptide/Carbonic Anhydrase (family) [3-171]
Interaction partners: - Transcriptional repressor PaaX
- Bifunctional protein PaaZ
- Acyl-coenzyme A thioesterase PaaI
- 1,2-phenylacetyl-CoA epoxidase, subunit B
- Phenylacetate-coenzyme A ligase
- 1,2-phenylacetyl-CoA epoxidase, subunit A
- 1,2-epoxyphenylacetyl-CoA isomerase
- 3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase
- 1,2-phenylacetyl-CoA epoxidase, subunit C
- 3-hydroxyadipyl-CoA dehydrogenase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0008374 (O-acyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006575 (cellular modified amino acid metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006577 (amino-acid betaine metabolic process), GO:0009437 (carnitine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)
Protein: Protein LSM14 homolog A-A (RNA-associated protein 55A-A) (RAP55A-A) (xRAP55) (xRAP55A) (A0A8M2)
Organism: Xenopus laevis (African clawed frog)
Function: RNA-binding component of messenger ribonucleoprotein complexes (mRNPs), storage particles that mask maternal mRNAs from the translational apparatus during oocyte maturation. Acts as a repressor of mRNA translation. Probably involved in the storage of translationally inactive mRNAs in the cytoplasm in order to prevent their degradation.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:17074753}. Cytoplasm, P-body {ECO:0000250|UniProtKB:Q8ND56}. Cytoplasm, Stress granule {ECO:0000250|UniProtKB:Q8ND56}. Note=Localizes to cytoplasmic particles in stage VI oocytes and eggs. {ECO:0000269|PubMed:17074753}.
Sequence: MSGGTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRPIPPRDEIFEYIIFRGSDIKDLTVCEPPKPQCSLPQDPAIVQSSLGSSSASSFQSVSSYGPFGRMPAYSQFNTGPLVGPQFGAVGVGSSLTSFGAETTSSTSLPPSSAVGTSFTQEARTLKTQSSQGQSSSPLDSLRKSPNIEQAVQTAAAPHAPSTATVGRRSPVLSRPVPSSIQKTAESPEQRKGELHKMQRPDIDQLKNDKNDPSKRQPVLSALQPRRGRGGNRGGRGRFGVRRDGPMKFEKDFDFESANAQFNKEEIDREFHNKLKIKDDKPEKPVNGEDKTDSVVDTQNSEGNAEEEEVLAGGVCYYDKTKSFFDNISCDDNRDRRQTWAEERRINVETFGLPLRSNRGRGGFRGRGGGMGFRGGRGRGGERRGAPGGGGFGPARGFRGGFRGGRGGREFADYEYRKDNKVAA
InterPro domains: - IPR025761: FFD box (domain) [363-379]
- IPR047575: Sm domain (domain) [1-81]
- IPR010920: LSM domain superfamily (homologous_superfamily) [6-84]
- IPR025762: DFDF domain (domain) [288-324]
- IPR019050: FDF domain (domain) [294-402]
- IPR025768: TFG box (domain) [382-402]
- IPR025609: Lsm14-like, N-terminal (domain) [1-98]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003723 (RNA binding), GO:0003690 (double-stranded DNA binding), GO:0003725 (double-stranded RNA binding), GO:0003727 (single-stranded RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0034248 (regulation of amide metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0051246 (regulation of protein metabolic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:0006417 (regulation of translation), GO:0010608 (post-transcriptional regulation of gene expression), GO:2000112 (regulation of cellular macromolecule biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1990904 (ribonucleoprotein complex)
Protein: Protein MAK16 homolog (Q57WF3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MNHDDAMWNVMGQTFCSFKVKTHDDKARFCRNPYNVTGLCQRGVCPLSNAQYATVVEHDDELYLYVKTAERAHLPRRQWEKVRLDANFPRALAQIDEELQWWDQKLVNKVKARLLRLKQYLMRRRKMLLEPKVEYVSVNKRQEDKLIRREAKAEAAARLELEVEKELLERLRSGTYDSVINCSLEAFERVLDREEDRTEFEALEDEEDEEFPEFVMDDELDEEEEMEESNRKIGKRGDSSVVHRSGRGTRRQRLVIEEEVEQEPVSKRVRTADLDW
InterPro domains: - IPR006958: Mak16 protein (family) [1-263]
- IPR029004: Ribosomal eL28/Mak16 (domain) [7-120]
Interaction partners: - RNA processing factor 1, putative
- Uncharacterized protein
- Ribosome biogenesis protein NSA1
- 60S ribosomal protein L24, putative
- rRNA processing protein, putative
- Ribosome biogenesis protein, putative
- CCAAT-binding factor domain-containing protein
- RNA-binding protein, putative
- Nucleolar GTP-binding protein 1
- Ribosome biogenesis protein NSA2 homolog
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0043168 (anion binding), GO:0042301 (phosphate ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0010467 (gene expression), GO:0042254 (ribosome biogenesis), GO:0016070 (RNA metabolic process), GO:0042273 (ribosomal large subunit biogenesis), GO:0006396 (RNA processing), GO:0034470 (ncRNA processing), GO:0000470 (maturation of LSU-rRNA), GO:0006364 (rRNA processing), GO:0034660 (ncRNA metabolic process), GO:0016072 (rRNA metabolic process), GO:0000463 (maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA))
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)
Protein: ASPSCR1 tether for SLC2A4, UBX domain containing (J3QL04)
Organism: Homo sapiens (Human)
Function: Not known
Sequence: MGVFPEAATKPLLSMGWCGKSLSACGSAGAPVLEDTCRRQDFNPCEYDLKFQRSVLDLSLQWRFANLPNNAKLEMVPASRSREGPENMVRIALQLDDGSRLQDSFCSGQTLWELLSHFPQIRECLQHPGGATPVCVYTRDEVTGEAALRGTTLQSLGLTGGSATIRFVMKCYDPVGKTPGSLGSSASAGQAAASAPLPLESGELSRGDLSRPEDADTSGPCCEHTQEKQSTRAPAAAPFVPFSGGGQRLGGPPGPTRPLTSSSAKLPKSLSSPGGPSKPKKSKSGQDPQQEQEQERERDPQQEQERE
InterPro domains: - IPR021569: TUG ubiquitin-like domain (domain) [32-75]
- IPR029071: Ubiquitin-like domain superfamily (homologous_superfamily) [32-81]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0009893 (positive regulation of metabolic process), GO:0019222 (regulation of metabolic process), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0051247 (positive regulation of protein metabolic process), GO:0051246 (regulation of protein metabolic process), GO:0031401 (positive regulation of protein modification process), GO:0031399 (regulation of protein modification process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0071944 (cell periphery), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: EF-hand domain-containing protein (Q580J5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Sequence: MLALSQGLPTVDPALVKAFKRAANNASTSGDVDDDSRRQEVARINKEAQKAWRAEEKSFIPAIYLRTRDPSAEDVLQHLRVTSKAFELNLRFRDIEQLDEMQVKLWSLLTADKSKQTVTISEFTEIMNKLKVWQGQRFEPTPKTSPCREISVRSAQQECPVDTTPLDEVMYVGVAKRPRPSLQLFLSCPRSHAGGVEVAHIYQRFAKQVSLVKCEAELLMWDTNNDGRLTEDELESYVRDLVSRVDALRDISNDILPFYCCAVSRRIFWALDPGMRGTIRIDALLQSPLMDEWVSLQLMREDLPRNWFSAAITSHLYDKFLLLDTRNQGTLNAANMKLYKKGLPTVRDDGLPRGVGPLSSLFIDRFFETSVMMACSELDFRKFVDFVIAVEFLPACQRPLFFWNILDIEGCGVLRPVHVNSFFRETHSKLVEAGLEMPSRETVVQEVFDLIPTAEPLRITREEFVKAPQAGLFVALLIDCLSFWAYENREQR
InterPro domains: - IPR011992: EF-hand domain pair (homologous_superfamily) [90-467]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [222-234]
- IPR002048: EF-hand domain (domain) [209-244]
- IPR039865: Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma (family) [44-492]
Interaction partners: - Serine/threonine-protein phosphatase
- Serine/threonine protein phosphatase 2a regulatory subunit, putative
- Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B
- EF-hand domain-containing protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0048870 (cell motility), GO:0007017 (microtubule-based process), GO:0001539 (cilium or flagellum-dependent cell motility), GO:0016043 (cellular component organization), GO:0000226 (microtubule cytoskeleton organization), GO:0044085 (cellular component biogenesis), GO:0030030 (cell projection organization), GO:0006996 (organelle organization), GO:0060285 (cilium-dependent cell motility), GO:0001578 (microtubule bundle formation), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0007010 (cytoskeleton organization), GO:0030031 (cell projection assembly), GO:0120036 (plasma membrane bounded cell projection organization), GO:0044782 (cilium organization), GO:0035082 (axoneme assembly), GO:0060271 (cilium assembly), GO:0120031 (plasma membrane bounded cell projection assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)