Protein: Protein 4.1 (Band 4.1) (Erythrocyte membrane protein band 4.1) (D4A9A6)
Organism: Rattus norvegicus (Rat)
Function: Not known
Subcellular location: Cytoplasm, cell cortex {ECO:0000256|ARBA:ARBA00004544}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Nucleus {ECO:0000256|ARBA:ARBA00004123}.
Sequence: MTTEKSLAAEAENSQHQKEEGEGATNSGQQESQLEEASQAAAAEGSNQGEQKLKASNGDTPTHEDLTKNKERTSESRGLSRLLSSFLKRPKSQVSEEEGREVESEREKGEGEQKETELGTSLDEDVILKAPIAAPEPELKTDPSLDLHSLSSIETQPAQEEHREDPDSETKEGEGIEECSGTEVKEDPESRAEREPETSQKPIRRHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLAVWDSTTSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTVQSELGDYDPELHGVDYVSDFKLAPNQTRELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEHYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTDTLPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRASRSLDGAAAAESTDRSPRPTSAPAIAQSQVMEGPGAPAKKAPKEAVKVEEKRGEEPAEPEPEPTEAWKVEKPHTEVTVPTSNGDQAQDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPFRTLNINGQVPTGDGPPLVKTQTVTISDTANAVKSEIPTKDVPIVHTETKTITYEAAQTEDSNGDLDPGVLLTAQTITSETTSSTTTTQITKTVKGGISETRIEKRIVITGDADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEISEE
InterPro domains: - IPR035963: FERM superfamily, second domain (homologous_superfamily) [290-395]
- IPR019747: FERM conserved site (conserved_site) [263-399]
- IPR029071: Ubiquitin-like domain superfamily (homologous_superfamily) [209-289]
- IPR008379: Band 4.1, C-terminal (domain) [709-816]
- IPR000798: Ezrin/radixin/moesin-like (family) [222-423]
- IPR018979: FERM, N-terminal (domain) [213-275]
- IPR000299: FERM domain (domain) [209-490]
- IPR019749: Band 4.1 domain (domain) [205-400]
- IPR014352: FERM/acyl-CoA-binding protein superfamily (homologous_superfamily) [287-394]
- IPR007477: SAB domain (domain) [625-671]
- IPR018980: FERM, C-terminal PH-like domain (domain) [404-494]
- IPR021187: Band 4.1 protein, FERM domain, F1 sub-domain (domain) [209-291]
- IPR014847: FERM adjacent (domain) [497-543]
- IPR019748: FERM central domain (domain) [291-400]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [395-489]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0030507 (spectrin binding), GO:0008092 (cytoskeletal protein binding), GO:0003779 (actin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0043933 (protein-containing complex organization), GO:0022607 (cellular component assembly), GO:0065003 (protein-containing complex assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098552 (side of membrane), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0098794 (postsynapse), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0045202 (synapse), GO:0098562 (cytoplasmic side of membrane), GO:0005886 (plasma membrane), GO:0099572 (postsynaptic specialization), GO:0009898 (cytoplasmic side of plasma membrane), GO:0098984 (neuron to neuron synapse), GO:0014069 (postsynaptic density), GO:0032279 (asymmetric synapse)