wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Hsp82-like protein (A0A2H0ZD43)
Organism: Candidozyma auris (Yeast) (Candida auris)
Subcellular location: Cytoplasm
Sequence: MPEKVETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPSQLETEPELFIRLTPKPEGKVLEIRDSGIGMTKTDLINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADHVQVISKHNDDEQYVWESNAGGKFTITLDETNERIKRGTIIRLFLKEDQLEYLEEKRIKEVVKRHSEFVSYPIQLVVKKEVEKEVPVEEDEKKEDEEKKEDEDDKKPKLEEVEDEDEKKEKTKKVKEEVTETEELNKTKPLWTRNPNDVSKEEYNAFYKSISNDWEDPLAVKHFSVEGQLEFKAILFVPKRAPFDAFESKKKKNNIKLYVRRVFITDDAEELIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIETFNEIAEDSEQFEKFYSAFSKNIKLGIHEDQQNRPALAKLLRFYSTKSTEEYTSLSDYVTRMPEHQKNIYYITGESIKAVEKSPFLDALKAKNFEVLFLVDPIDEYAMTQLKEFEDKKLVDITKDFELEETEEEKKQREKEIEEFEPLTKSLKEILGDQVEKVVVSHKLVDAPAAIRTGQFGWSANMERIMKAQALRDTTMSSYMSSKKTFEISPKSPIIKELKKKVDADGAEDKTVKDLTTLLYETALLTSGFSLEEPSSFAHRINRLISLGLNIEDDEPETAEVGTTATASTEEPAAESAMEEVD
InterPro domains: - IPR001404: Heat shock protein Hsp90 family (family) [3-706]
- IPR020568: Ribosomal protein uS5 domain 2-type superfamily (homologous_superfamily) [271-526]
- IPR036890: Histidine kinase/HSP90-like ATPase superfamily (homologous_superfamily) [4-240]
- IPR037196: HSP90, C-terminal domain (homologous_superfamily) [526-676]
- IPR003594: Histidine kinase/HSP90-like ATPase domain (domain) [28-166]
- IPR019805: Heat shock protein Hsp90, conserved site (conserved_site) [26-35]
- IPR020575: Heat shock protein Hsp90, N-terminal (domain) [6-207]
Interaction partners: - Response regulatory domain-containing protein
- STI1 domain-containing protein
- CS domain-containing protein
- Hsp90 chaperone protein kinase-targeting subunit
- Activator of Hsp90 ATPase AHSA1-like N-terminal domain-containing protein
- Peptidyl-prolyl cis-trans isomerase D
- Uncharacterized protein
- Rap-GAP domain-containing protein
- Serine/threonine-protein phosphatase
- Heat shock transcription factor
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0048583 (regulation of response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0048585 (negative regulation of response to stimulus), GO:0009408 (response to heat), GO:0009266 (response to temperature stimulus), GO:0080134 (regulation of response to stress), GO:0080135 (regulation of cellular response to stress), GO:1900034 (regulation of cellular response to heat)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0005654 (nucleoplasm), GO:0043233 (organelle lumen), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0005634 (nucleus)
Protein: Vanadate resistance protein (A0A2H0ZMV6)
Organism: Candidozyma auris (Yeast) (Candida auris)
Sequence: MVFKDKASDLPIYNNRFRPRRPSRGLIRGIFIGAVILLLIWGFLQRNTKFNFSIQEKAVLTEDYDLYTVTKDGVQKVEPQDAATDEEAERIYKETVSFYDLNDYQGTTRGESANEVVLFLMPLRNAEHVLPMAFQNIMNLTYDHSLIDIAFLVSDCSPGDTTLESVFKYSISLQNGTLADELLMAEQDKLKNSVKGTNDLYENYMDQAYMENVRKAYNSPETWHKGYRTPFRSVSIYVKDFGQVIGQGFSDRHAVKVQGIRRKLMGRARNWLTASALQPHHSWVYWRDVDIETCPGSVIQDLMKFDYDVMVPNIWRPLPSFLDNEQPYDLNSWVESDAALELAKKLDEDDVIVEGYAEYPTWRVHLAYLRDANGNPNEVLDLDGVGGVSILAKAKIFRQGVHFPAFTFLNHAETEAFGKMAKKMGFKVGGLPHYTIWHIYEPSEDDLKKIAAMERQKRRQKGG
InterPro domains: - IPR029044: Nucleotide-diphospho-sugar transferases (homologous_superfamily) [92-449]
- IPR052086: Mannan Polymerase Complex Subunit (family) [24-448]
Interaction partners: - Uncharacterized protein
- Mannosyltransferase OCH1
- Mannosyltransferase OCH1
- ornithine carbamoyltransferase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0000030 (mannosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0022008 (neurogenesis), GO:0030182 (neuron differentiation), GO:0007399 (nervous system development), GO:0048699 (generation of neurons)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:1902494 (catalytic complex), GO:0005737 (cytoplasm), GO:0098796 (membrane protein complex), GO:0031984 (organelle subcompartment), GO:0012505 (endomembrane system), GO:0140535 (intracellular protein-containing complex), GO:0031501 (mannosyltransferase complex), GO:0031090 (organelle membrane), GO:0005794 (Golgi apparatus), GO:1990234 (transferase complex), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0098791 (Golgi apparatus subcompartment), GO:0031985 (Golgi cisterna), GO:0043231 (intracellular membrane-bounded organelle), GO:0005795 (Golgi stack), GO:0098588 (bounding membrane of organelle), GO:0000139 (Golgi membrane), GO:0000137 (Golgi cis cisterna)
Protein: Exopolyphosphatase (Q59X24)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Sequence: MSIKSYLTNLRQQLKSKSLNSPLTVVTGNQSADMDSVVSALTFAYFSNLHSKQYIIPLINIPRRDLKLRRDIVTLLDYYSITEDLLFFVEDFQNIVKESDQILINLVDHNNIQGDELHEAFGAGKLKVVGIIDHHEDEGQFVESQPRIIRTCGSNSSLVFNYFYNEFFKSNTSKFLETQLEAIKLLLGPLLIDTSGMTQKVEEPDTEAFSIYQKALEGDEKFIQLFANSGDKDPYTNYYSTLKAAKKDVSGFKFVDLLRKDYKQFTFDSGDRVGFSSVTKAFKWIVANYSKEEIGKTLIKTLEENNIDLLIIGTHFTRKDNDKYTREFGYYYKKSENEKFNNLHNLAETKLQLNNEVYGADKIVSTVETLSSHGNFKVFNQGNISASRKQVVPIVKEILEN
InterPro domains: - IPR001667: DDH domain (domain) [25-169]
- IPR038763: DHH phosphoesterase superfamily (homologous_superfamily) [23-399]
- IPR038222: DHHA2 domain superfamily (homologous_superfamily) [248-401]
- IPR004097: DHHA2 domain (domain) [239-399]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0008081 (phosphoric diester hydrolase activity), GO:0004112 (cyclic-nucleotide phosphodiesterase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006091 (generation of precursor metabolites and energy), GO:0015980 (energy derivation by oxidation of organic compounds), GO:0045333 (cellular respiration), GO:0009060 (aerobic respiration)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0009986 (cell surface), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062039 (biofilm matrix), GO:0062040 (fungal biofilm matrix)
Protein: Pet127p (A0A1D8PF16)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Sequence: MIRRNILVIQGRSFCQSSYLAESLKPKPDIENKVTTNGDSNDITKIALNTNKPGDDGSLKRDDRVKNLINRLTATGRHEAKRNPTTTNASDAYKLFQNPDKLKALKRMFAQPKVSKRRVKKHVKEKFQKKHTEKNTKTSTEPFFKDKSTDKYLTSNNIKKHNLEQFVAPKNEDIARLAHNLDRVLFSPGVHFLQDPRTRIYNFSPFLKKVIHYKDFNFKAIENYTPVSKHQQLLENSQKFEKQFYSSTSSMTSLLSKFYHFLNKYDRYNVKRFGPIPFTGMSNDLPTNLILKPQGEFMDSTTKEKKPVYSIQADNSCDLDTLLSAMGMCMETLLTNPQNEFVKYHKDSGVEFNEPLGNTYNYASYGDFLLRSQLDCYDERLPGNGTFDLKTRASSNIRYNSKSGSLEKNDYQIWRLNGTYESYEHEFRDMIRTGAMLKYLFQARIGQMDGIFIAYHSINTIFGFQYLPLEELDKLFYTRDTISEFPDVSVRNLNEHRLPDKLPSLIGETQFKFSLEIWQKLLQEHILKDLNKEFNNKPTPFRLSVKYDALAHLLRVFVIPATDEEIDVLQSFPERFKRDFAEDENLGEVKKHARELTKFNEKCLETKEVFSYVIQMDSCMIDGKIRQYHQLPRDYFKDWQLIYNIKRTSNAPKKYVSNLLRFPDTKISQRLKKVHQLYEKIGSIRKKSWQEKDKKSQVYHPKFKF
InterPro domains: - IPR013943: Mitochondrial protein Pet127 (family) [32-699]
Interaction partners: - Rmp1p
- Sister chromatid cohesion protein
- ATP synthase subunit a
- ATP synthase subunit 9, mitochondrial
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0004518 (nuclease activity), GO:0004527 (exonuclease activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0140053 (mitochondrial gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0000963 (mitochondrial RNA processing), GO:0000966 (RNA 5'-end processing), GO:0000959 (mitochondrial RNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Protein-arginine N-methyltransferase (A0A1D8PGT0)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Sequence: MKYIIEHMEEGFSEWVILEYTQIIKDIGKDNLILTSLPPSTTEKDIPKRLLELGLQWTTKECVDIDGGIDKSKVCLLDPAAETDLTPQDKSKFDYFVFGGILGSHPRIDRTGLLREKYGFSGRRLGSLQMTTDTAIRTTQRIIENGVAFEDIKFLDYPEIKYNKYESTEMPFRYVTDNEGNPILPEGMLELIKNDAEQSIDDLLIE
InterPro domains: - IPR007364: Protein arginine N-methyltransferase SFM1-like (family) [2-204]
Interaction partners: - ATP-dependent permease
- Amine oxidase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0008276 (protein methyltransferase activity), GO:0008168 (methyltransferase activity), GO:0016274 (protein-arginine N-methyltransferase activity), GO:0008757 (S-adenosylmethionine-dependent methyltransferase activity), GO:0008170 (N-methyltransferase activity), GO:0016273 (arginine N-methyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhesion), GO:0031589 (cell-substrate adhesion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0031012 (extracellular matrix), GO:0062039 (biofilm matrix), GO:0062040 (fungal biofilm matrix)
Protein: PH domain-containing protein (A0A1D8PF97)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus
Sequence: MEAMKKRMTTHSPKPESPKPATSPDSDSLEGLSPELVPIVTLLSSQAHRRYNEGIFMLYYDLNGDGKPADREWREVYGILTGNQLAYWDAANLAQFKNNPSALLETSSKPNYINFTDSVYNAMKTLPAAKQNLDNVIIVSTTLKNRYLLQFKSYKDLTVWYAALRLSNFEYSSLQEAYTGALLSARGSRLSDIRTILAEKRFDHEDWVSIRYGSGMAWKRCFAVVEPSTLKKKVFTPGRILFYENEQKKKKQLMAMVTNATAVAAIYPQSHLLIDHSTMLKMEGYINFTSPSLSTKVSKKSASDFKHTSLFLMPEQHSSVPGFDTLIRFLVPLLDSFGLYGRPKRLKANRNDTDSLLFGLPTLPHVHYLELNDVLDLTRGDFLSWDLKTWTDNIKGILKTKIDRGYEGCGSQRGIKGAVTSLSSPVTSTGSPRFASGQGFSSRSTSSSSSQPRQNQQTPQQRKPPPPGPELKPAGKSFDKNVNDLHIGVSNDNLLSADKMKNNHKSVQLAEIYQKYSDLKTPSDNYTDRNILLNGSHEHLMEDELPAGIQQMKLHDNIYPKDDDGLFSDDDDDDDLAKVDVRKIGMNNDGSSQSLDPTLGALKVPYSDDRAGSYSSVISPMSQFNNLKESYQNVDRRAPYPNNSDNESDDDSPPPPVPSHDQKYQTGLQGKSSAFSQGAATSRGAGGMINGSSSESRSQGQQKPKYISSPNSSQNHIHRIHSPEKGSPLGRANVQYPISPERLTDVHKSSDNLADAIKLPVLPAINKVPPQEEQRQPQKYPQPQPQPQSQPHPYQQQQQQQQPRQQQLYSPQQVQQQKYHQQQQQQLQQQQQQYYQQQKFQQSQQPQRPLQQQQQQPPQQQHYQKQPQQQPQQQPHRVPPPQQQPQQQLSQAYRAAPPTQQKQPPPQQQLYGRSQPQSFPREPPNGHPQGSGFMQNRGVIPRNNGQAPPPQPQNGARGFVSQQQQQQQQQYQYSYLPSGASGQPKQQQQQQPQQQPQPHRGHHPYGAQYTSQNPNGQARYY
InterPro domains: - IPR001849: Pleckstrin homology domain (domain) [49-169]
- IPR058155: Skg3/CAF120-like, PH-like domain (domain) [190-358]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [44-168]
Interaction partners: - CCR4-NOT core ubiquitin-protein ligase subunit
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0030447 (filamentous growth), GO:0071840 (cellular component organization or biogenesis), GO:0051641 (cellular localization), GO:0071554 (cell wall organization or biogenesis), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0051649 (establishment of localization in cell), GO:0016043 (cellular component organization), GO:0030448 (hyphal growth), GO:0071852 (fungal-type cell wall organization or biogenesis), GO:0046907 (intracellular transport), GO:0071555 (cell wall organization), GO:0045184 (establishment of protein localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0006886 (intracellular protein transport), GO:0031505 (fungal-type cell wall organization), GO:0071705 (nitrogen compound transport), GO:0008104 (protein localization), GO:0045229 (external encapsulating structure organization), GO:0015031 (protein transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0030427 (site of polarized growth), GO:0005933 (cellular bud), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0060187 (cell pole), GO:0001411 (hyphal tip), GO:0005935 (cellular bud neck), GO:0005938 (cell cortex), GO:0051286 (cell tip)
Protein: Endopolyphosphatase (A0A1D8PQR0)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths
Subcellular location: Vacuole membrane; Single-pass type II membrane protein
Sequence: MENIGPNRSSARQYLLITFLITFVVSISTYLYCADYVSYNIWNSVTSKSNKPYISIKTLDLNDTQIDDLKRLGLTPKKSVEIVKPDNSKQTIHGRFLHITDFHIDHHYQKGSDIDKVCHGGEGKASKYGDAILGCDSPPILVEETFKWITDNLIDKIDFIVYTGDSARHDNDREYPRTRQHIFNMNKEISDKFVTLTSESDGQPLIYPVSNNDIMPHNLMDTGPSLQTRELFEAWRPFIPQVQMHTYLMGAYYFQEVIPNQLAVLSLNTMYWFDSNPMVDDCDNKGDPGYKLFEWLGYVLKEMRARNMKVWLCGHVPPNEKNYDTTCLRKYIAWTHEYRDVIVGGLYGHMNLDHFIPLDSVQAYKSIQKDFKDEFKQKSVFSVEDEDDLALEDSNLYKALDENFSDKFFRVTGGVPNNKVTYLETLREELYAPLKGKKKSGEHFERYSIAHVTASIIPTFNPGMRVWEYNITDLEDKLQQVKFEPWDKFFAGVERMIEVQSNYVDEKDNDEMNWQEMDDITIERKKKHKKKNRKKKKDHTFPKPMPENLPLGPAYIEQTFTPERYVQYYADLESINKGKKEFDYEIEYSTDDSLYGLKALTVEEWIKFGRKLGEPVKDLKNNVNKGKKKKNNGKKYKKLQQIWNAYLKHAFISSDYEHKGYG
InterPro domains: - IPR041805: Acid sphingomyelinase/endopolyphosphatase, metallophosphatase domain (domain) [96-360]
- IPR029052: Metallo-dependent phosphatase-like (homologous_superfamily) [95-350]
- IPR012358: Endopolyphosphatase, Ppn1p-related (family) [71-657]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrolase activity), GO:0008081 (phosphoric diester hydrolase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0009056 (catabolic process), GO:0044248 (cellular catabolic process), GO:0006082 (organic acid metabolic process), GO:0006793 (phosphorus metabolic process), GO:0006797 (polyphosphate metabolic process), GO:0043436 (oxoacid metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0005773 (vacuole), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0000323 (lytic vacuole), GO:0043231 (intracellular membrane-bounded organelle), GO:0000322 (storage vacuole), GO:0000324 (fungal-type vacuole)
Protein: Lhp1p (A0A1D8PE36)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Subcellular location: Nucleus
Sequence: MTDFVYQGEDFDEKVRKQVEFYFSDSNLQTDKFLWKIYESNDGWVELKTILTFGRMRQYRPEDKVISALKESKKLVLSANNDMIRRKDPIKDFNEVKNTRKRNTIHIEGFPKDLSQDDVENWVNEKVIVQLPKEKEVCSIRRIKSRAKKEFFGVVDIEFKTQEDAEFILNNVELSYPEGIISKEDAQSLEKKDLLKKMTLLTFQEMRESSKRFGVNEVTKRRNSFNENHKGGNKKFKKGNNNGKGKNNKNENDNGNGTEDKETKLEKVEEIDSTKENTEEVAAKETAPESTEKTETKEAPAPTTETETETKTEVTEATEAAKEE
InterPro domains: - IPR002344: Lupus La protein (family) [18-169]
- IPR035979: RNA-binding domain superfamily (homologous_superfamily) [94-170]
- IPR006630: La-type HTH domain (domain) [5-95]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [8-93]
- IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [5-91]
- IPR045180: La domain containing protein (family) [9-302]
- IPR012677: Nucleotide-binding alpha-beta plait domain superfamily (homologous_superfamily) [94-194]
Interaction partners: - Tif3p
- Translation initiation factor eIF2B subunit delta
- Eukaryotic translation initiation factor 5A
- RNA-binding protein VTS1
- Pumilio homology domain family member 3
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0000049 (tRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0034470 (ncRNA processing), GO:0034660 (ncRNA metabolic process), GO:0006399 (tRNA metabolic process), GO:0008033 (tRNA processing)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005618 (cell wall), GO:0009536 (plastid), GO:0043231 (intracellular membrane-bounded organelle), GO:0009277 (fungal-type cell wall), GO:0030446 (hyphal cell wall), GO:0005634 (nucleus)
Protein: Ribosome biogenesis regulatory protein (A0A1D8PCC8)
Organism: Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Function: Involved in ribosomal large subunit assembly
Subcellular location: Nucleus
Sequence: MSSEKEYKPVTVDKPIPNTYDLGNLATFDPNPLDNEKLLSKDESIKEDHLQSVTRDNVQLLINQILSLPVKITTETHGSSTGQNSTMTLIQLPEPTTILPREKPIPKAKPLTKWQQFAARKGIKPKAKDGKMVYDEDTGEWVPKWGYKGKNKSIDDQWLVEVDDKVKNTEDELIDPRTLKRAERKKLIKKNELQHKRNLRNQGAV
InterPro domains: - IPR007023: Ribosomal biogenesis regulatory protein (family) [18-199]
Interaction partners: - Ribosome production factor 2 homolog
- rRNA-binding ribosome biosynthesis protein
- rRNA-processing protein EBP2
- Ribosome assembly factor mrt4
- rRNA-processing protein CGR1
- Ribosome biogenesis protein RLP24
- Rpl7p
- Cic1p
- 60S ribosome subunit biogenesis protein NIP7
- RNA-binding GTPase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus), GO:0030447 (filamentous growth), GO:0006950 (response to stress), GO:0009607 (response to biotic stimulus), GO:0007154 (cell communication), GO:0009991 (response to extracellular stimulus), GO:0031668 (cellular response to extracellular stimulus), GO:0044182 (filamentous growth of a population of unicellular organisms), GO:0036180 (filamentous growth of a population of unicellular organisms in response to biotic stimulus), GO:0042594 (response to starvation), GO:0071496 (cellular response to external stimulus), GO:0033554 (cellular response to stress), GO:0036170 (filamentous growth of a population of unicellular organisms in response to starvation), GO:0009267 (cellular response to starvation), GO:0031669 (cellular response to nutrient levels), GO:0031667 (response to nutrient levels)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:1990904 (ribonucleoprotein complex), GO:0030684 (preribosome), GO:0032040 (small-subunit processome)