Protein: Thy-1 membrane glycoprotein (Thy-1 antigen) (CD antigen CD90) (P01831)
Organism: Mus musculus (Mouse)
Function: May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor.
Sequence: MNPAISVALLLSVLQVSRGQKVTSLTACLVNQNLRLDCRHENNTKDNSIQHEFSLTREKRKHVLSGTLGIPEHTYRSRVTLSNQPYIKVLTLANFTTKDEGDYFCELQVSGANPMSSNKSISVYRDKLVKCGGISLLVQNTSWMLLLLLSLSLLQALDFISL
InterPro domains: - IPR033292: Thy-1 membrane glycoprotein (family) [1-162]
- IPR013106: Immunoglobulin V-set domain (domain) [33-107]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [29-111]
- IPR007110: Immunoglobulin-like domain (domain) [3-122]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [14-126]
- IPR013151: Immunoglobulin-like beta-sandwich domain (domain) [26-113]
Interaction partners: - Integrin alpha-M
- Integrin beta-2
- 5'-nucleotidase
- Endoglin
- Receptor-type tyrosine-protein phosphatase C
- Hematopoietic progenitor cell antigen CD34
- Integrin beta-2-like protein
- Rho GTPase-activating protein 35
- Rho GTPase-activating protein 5
- Ephrin type-A receptor 4
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0050839 (cell adhesion molecule binding), GO:0005178 (integrin binding), GO:0005102 (signaling receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0040017 (positive regulation of locomotion), GO:0002684 (positive regulation of immune system process), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0002682 (regulation of immune system process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0040012 (regulation of locomotion), GO:0048522 (positive regulation of cellular process), GO:2000145 (regulation of cell motility), GO:0002685 (regulation of leukocyte migration), GO:0030155 (regulation of cell adhesion), GO:0007166 (cell surface receptor signaling pathway), GO:0051130 (positive regulation of cellular component organization), GO:0045785 (positive regulation of cell adhesion), GO:0051128 (regulation of cellular component organization), GO:0044089 (positive regulation of cellular component biogenesis), GO:2000147 (positive regulation of cell motility), GO:0002687 (positive regulation of leukocyte migration), GO:0044087 (regulation of cellular component biogenesis), GO:1901890 (positive regulation of cell junction assembly), GO:0150117 (positive regulation of cell-substrate junction organization), GO:0010811 (positive regulation of cell-substrate adhesion), GO:0007229 (integrin-mediated signaling pathway), GO:0022409 (positive regulation of cell-cell adhesion), GO:0010810 (regulation of cell-substrate adhesion), GO:1901888 (regulation of cell junction assembly), GO:0022407 (regulation of cell-cell adhesion), GO:0002691 (regulation of cellular extravasation), GO:0030335 (positive regulation of cell migration), GO:0030334 (regulation of cell migration), GO:0150116 (regulation of cell-substrate junction organization), GO:0002693 (positive regulation of cellular extravasation), GO:0034114 (regulation of heterotypic cell-cell adhesion), GO:0051894 (positive regulation of focal adhesion assembly), GO:0090109 (regulation of cell-substrate junction assembly), GO:0001954 (positive regulation of cell-matrix adhesion), GO:0001952 (regulation of cell-matrix adhesion), GO:0051893 (regulation of focal adhesion assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0098552 (side of membrane), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0009986 (cell surface), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0009897 (external side of plasma membrane), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0070161 (anchoring junction), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0005769 (early endosome), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0005911 (cell-cell junction), GO:0043296 (apical junction complex), GO:0070160 (tight junction), GO:0097708 (intracellular vesicle), GO:0005923 (bicellular tight junction)