Protein: Citrate synthase (Q388Q5)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MCMRARYSSGIVRGAMLRGFSSSPSLFCAAAGGSPIFDELKLSILKKHQSDAPRIKQLIAKHGGDKLSESTVSSMYGGMRGVTGFVYEPSYLDKEVGIRFRGLTISECCEKLPKSWRGGSSPLPEGMLWLLVTGTIPNERQVKEMHEELHRRADERAISAAVKTIASLPDNSHPMTQFGAGLMALQTYSKFATAYSQGKANKTNYWEYALDDSLDLIARSSHVAAIVYNRLATGKAQLANPSDPNLDWAANFTNMLGYKDESFWDCMRLYLCLHADHEGGNVSAHATVLVASALSDPYLSLVAGLAGLAGPLHGLANQEVLTYLFEMRDKCKAAGVDLHDRKRLAAELEKLTWDVLNAKRVVPGYGHAVLGMTDPRYTCFREYCKNNFPNDELFILVDAIYEIMPGILKKHGKVRNPFPNVDAQSGVLLQHYGMKEQLFYTVLFGLSRQLGVLTGIVWDRLQGRPIERPKTMTSESLLTKYNIA
InterPro domains: - IPR016143: Citrate synthase-like, small alpha subdomain (homologous_superfamily) [316-438]
- IPR016142: Citrate synthase-like, large alpha subdomain (homologous_superfamily) [52-470]
- IPR036969: Citrate synthase superfamily (homologous_superfamily) [44-478]
- IPR002020: Citrate synthase (family) [45-481]
Interaction partners: - Aconitate hydratase
- Acetyl-coenzyme A synthetase
- Malate dehydrogenase
- Succinate--CoA ligase subunit beta, mitochondrial
- malate dehydrogenase
- malate dehydrogenase
- Malate dehydrogenase
- Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
- Dihydrolipoamide acetyltransferase, putative
- hydroxymethylglutaryl-CoA lyase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0046912 (acyltransferase activity, acyl groups converted into alkyl on transfer), GO:0036440 (citrate synthase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0044281 (small molecule metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0055086 (nucleobase-containing small molecule metabolic process), GO:0044248 (cellular catabolic process), GO:0019637 (organophosphate metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:1901575 (organic substance catabolic process), GO:0006790 (sulfur compound metabolic process), GO:1901135 (carbohydrate derivative metabolic process), GO:0035383 (thioester metabolic process), GO:0006793 (phosphorus metabolic process), GO:0034655 (nucleobase-containing compound catabolic process), GO:0044270 (cellular nitrogen compound catabolic process), GO:0006753 (nucleoside phosphate metabolic process), GO:0044273 (sulfur compound catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0006637 (acyl-CoA metabolic process), GO:1901136 (carbohydrate derivative catabolic process), GO:0019693 (ribose phosphate metabolic process), GO:0019439 (aromatic compound catabolic process), GO:1901361 (organic cyclic compound catabolic process), GO:0046700 (heterocycle catabolic process), GO:0006796 (phosphate-containing compound metabolic process), GO:0072521 (purine-containing compound metabolic process), GO:0046434 (organophosphate catabolic process), GO:0009261 (ribonucleotide catabolic process), GO:0009259 (ribonucleotide metabolic process), GO:0072523 (purine-containing compound catabolic process), GO:1901292 (nucleoside phosphate catabolic process), GO:0009117 (nucleotide metabolic process), GO:0006163 (purine nucleotide metabolic process), GO:0034032 (purine nucleoside bisphosphate metabolic process), GO:0033865 (nucleoside bisphosphate metabolic process), GO:0034034 (purine nucleoside bisphosphate catabolic process), GO:0009154 (purine ribonucleotide catabolic process), GO:0009150 (purine ribonucleotide metabolic process), GO:0033869 (nucleoside bisphosphate catabolic process), GO:0009166 (nucleotide catabolic process), GO:0006195 (purine nucleotide catabolic process), GO:0033875 (ribonucleoside bisphosphate metabolic process), GO:0034031 (ribonucleoside bisphosphate catabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)