Protein: ATP-binding cassette sub-family C member 5 (Multidrug resistance-associated protein 5) (E1B2R7)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004370}.
Sequence: MKGHDLGKDCLAAGSAYRAVPSRETLPGPDGDHYELSKVQDAFETAARAEGGLSLDRGNAADAKELEEDAAGRSKYHHSVCVLKPIRSTSKYQHPVDNAGLFSFMTFNWLTSLAVLAHKKGQLFLEDIWAVSQFESCEINRRRLAGLWEEEIRSRGNDASLRRVVWHFCRTRLLLSILCLMVTQLAGFSSPAFVVWRLLEYTQRSEPDLPYGLLLVLGLLATELIRSWSHALTWALNYRTGTRLRGAILTMAFHKILRLRSLREKSMGELINMCSGDGQRMFEAAAVGSLLAGGPLVAVLGMAYNLFVLGPTSLLGSAVFILFYPTMMFSSRLTAYFRRKGVAVTDQRVQKMNEILNYIKFIKMYAWVKAFSQAVRRIRDEERQILERTGYFQSITVGVAPIVVVIASVATFSTHMLLGYDLTAAQAFTVVTVFNAMTFALKVTPFSVKSLSEASVAIDRFKSLLLMAEVKMIRELPRNPSVAVEMSGASLAWETGGHSAQPSPRGTPHVGTRGCRKKRRQRDVPKHHAILEEETHGQLLNDVSGEMASSPKDQTLHVPTISQRLQRTLHCIDLSIQKGKLVGVCGSVGSGKTSLISAILGQMTLLEGTVAVDGDFAYVAQQAWILNASFRDNILFGKEMEEERYQAILSACCLRPDLAMLPSGDLTEIGERGANLSGGQRQRISLARALYSNRGIYILDDPLSALDAHVGNHIFNNAIKKQLRGKTVIFVTHQLQYLVDCDDVIVMRDGSIAEQGSHEDLMNVNGDYAAMFNNLQLGETPIIEVPNKKSGSSLKKPLEKSKAGSVKKEKSTTQGDGQLMQVEERGKGSVPWAVYKVYIQALGGWPVFLFILALFILNVGSTAFSNWWLCYWIKQGSGNTTVQVGNSSVLSESMRDNPLMQHYAAVYTMSMGVMLLLKLLRGIVFVKGTLRASSRLHDELFQKILRSPMKFFDTTPTARILNRFSKDMDEVDTRLPFQAEMFTQNVILVLFCLAVIGSVFPWFLVAVGPLVLLFTVLHVVSRVFIRELKRLDNVTQSPFLSHIASSIQGLTTVHAYGKEDEFLHRYQELLDQNQAPFYLFSCAMRWLAVRLDVISVALISITALMIVLMHGQIPPAYAGLAISYAVQLTGLFQFTVRLASETEARFTSVERIHHYIKSLSLEAPARVKNKAPPSDWPQEGEIVFDQTEMKYRDNLPLILKKASFTVRPKEKIGIVGRTGSGKSSLGVVLYRLVEPCGGSIKIDGVNICDIGLADVRSKLSIIPQEPVLFSGTVRSNLDPFSQYSEAQIWDALERTHMKECVSQLPLKLESEVVENGENFSVGERQLLCVARVLLRQCKILILDEATAAMGTETDCLIQETIRNAFQDCTTLTIAHRVHTVLSCDRIMVLNQGQVVEFDEPSKLLANENSRFCAMLAAVENKISVRG
InterPro domains: - IPR017871: ABC transporter-like, conserved site (conserved_site) [676-1333]
- IPR036640: ABC transporter type 1, transmembrane domain superfamily (homologous_superfamily) [129-1158]
- IPR003593: AAA+ ATPase domain (domain) [578-1392]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [530-1419]
- IPR003439: ABC transporter-like, ATP-binding domain (domain) [553-1416]
- IPR050173: ATP-binding cassette transporter C-like (family) [98-1415]
- IPR011527: ABC transporter type 1, transmembrane domain (domain) [174-1144]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0140657 (ATP-dependent activity), GO:0042626 (ATPase-coupled transmembrane transporter activity), GO:0022857 (transmembrane transporter activity), GO:0140359 (ABC-type transporter activity), GO:0022884 (macromolecule transmembrane transporter activity), GO:0022857 (transmembrane transporter activity), GO:0022804 (active transmembrane transporter activity), GO:0015399 (primary active transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0042592 (homeostatic process), GO:0032502 (developmental process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0055085 (transmembrane transport), GO:0051234 (establishment of localization), GO:0048871 (multicellular organismal-level homeostasis), GO:0002262 (myeloid cell homeostasis), GO:0034101 (erythrocyte homeostasis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0098660 (inorganic ion transmembrane transport), GO:0006810 (transport), GO:0034220 (monoatomic ion transmembrane transport), GO:0048872 (homeostasis of number of cells), GO:0098655 (monoatomic cation transmembrane transport), GO:0030097 (hemopoiesis), GO:0098662 (inorganic cation transmembrane transport), GO:0071705 (nitrogen compound transport), GO:0030218 (erythrocyte differentiation), GO:0071702 (organic substance transport), GO:0030099 (myeloid cell differentiation), GO:0006811 (monoatomic ion transport), GO:0006812 (monoatomic cation transport), GO:0015886 (heme transport), GO:0034755 (iron ion transmembrane transport), GO:0030001 (metal ion transport), GO:0000041 (transition metal ion transport), GO:0006826 (iron ion transport), GO:1901678 (iron coordination entity transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)