Protein: Succinylornithine transaminase/acetylornithine aminotransferase (ACOAT) (SOAT) (Succinylornithine aminotransferase) (EC 2.6.1.11) (EC 2.6.1.81) (O30508)
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Function: Transaminates both N(2)-acetylornithine and N(2)-succinylornithine.
Subcellular location: Cytoplasm {ECO:0000305}.
Sequence: MSAPHAQVERADFDRYMVPNYAPAAFIPVRGEGSRVWDQSGRELIDFAGGIAVTSLGHAHPALVKALTEQAQRIWHVSNVFTNEPALRLARKLVDATFAERVFLANSGAEANEAAFKLARRYANDVYGPQKYEIIAASNSFHGRTLFTVNVGGQPKYSDGFGPKFEGITHVPYNDLEALKAAISDKTCAVVLEPIQGEGGVLPAQQAYLEGARKLCDEHNALLVFDEVQSGMGRVGELFAYMHYGVVPDILSSAKSLGGGFPIGAMLTTGEIAKHLSVGTHGTTYGGNPLASAVAEAALDVINTPEVLDGVKAKHERFKSRLQKIGQEYGIFDEIRGMGLLIGAALTDEWKGKARDVLNAAEKEAVMVLQASPDVVRFAPSLVIDDAEIDEGLERFERAVAKLVRG
InterPro domains: - IPR005814: Aminotransferase class-III (family) [5-403]
- IPR050103: Class-III Pyridoxal-phosphate-dependent Aminotransferase (family) [11-401]
- IPR004636: Acetylornithine/Succinylornithine transaminase family (family) [16-403]
- IPR015421: Pyridoxal phosphate-dependent transferase, major domain (homologous_superfamily) [60-305]
- IPR017652: Acetyl/Succinylornithine transaminase family, bacteria (family) [8-404]
- IPR049704: Aminotransferases class-III pyridoxal-phosphate attachment site (conserved_site) [223-260]
- IPR015424: Pyridoxal phosphate-dependent transferase (homologous_superfamily) [16-402]
- IPR015422: Pyridoxal phosphate-dependent transferase, small domain (homologous_superfamily) [30-393]
Interaction partners: - N-succinylglutamate 5-semialdehyde dehydrogenase
- N-succinylarginine dihydrolase
- Arginine N-succinyltransferase subunit beta
- Arginine N-succinyltransferase subunit alpha
- Succinylglutamate desuccinylase
- Arginine biosynthesis bifunctional protein ArgJ
- N-acetyl-gamma-glutamyl-phosphate reductase
- Amino-acid acetyltransferase
- Acetylglutamate kinase
- Argininosuccinate synthase
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016769 (transferase activity, transferring nitrogenous groups), GO:0008483 (transaminase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044281 (small molecule metabolic process), GO:0009056 (catabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006520 (amino acid metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0044282 (small molecule catabolic process), GO:1901575 (organic substance catabolic process), GO:0006082 (organic acid metabolic process), GO:0044248 (cellular catabolic process), GO:0016054 (organic acid catabolic process), GO:1901565 (organonitrogen compound catabolic process), GO:0043436 (oxoacid metabolic process), GO:1901605 (alpha-amino acid metabolic process), GO:0009063 (amino acid catabolic process), GO:0019752 (carboxylic acid metabolic process), GO:1901606 (alpha-amino acid catabolic process), GO:0009064 (glutamine family amino acid metabolic process), GO:0046395 (carboxylic acid catabolic process), GO:0009065 (glutamine family amino acid catabolic process), GO:0006527 (arginine catabolic process), GO:0006525 (arginine metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure)