Protein: SD16537p (Q7YU91)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MASQHSSWRFGKRSKLQLRIKVSQDPEDFYRLDPQRSAAENAFEIYSMLCLEETRDTKRLFLLNALASLCLGARKGSHHSNIRFTTEELLYCLSASLVHTFTQVRAAALRTIRYAISTPNDIKTFNALQLQHLLCRSIDLMLKNDDERVQALKLVRKMLAIAPEDISPAVVRCLVSLADSGIEENDNLLRACLATLAEFAVLNPALLIVCGGVTSITRNVLECHNPRIAESLCGVLLYLLEWPQTRNICGVRLDCLAAPYCDFTYRQSIVDKNKDARELRYTSCRLALLSVLRSWTGTLEFCDPSKPSGLKAIVDALYLNQIEVRKAILDLLYELLTLPQPTWTDDYAVALQAVDPSDFQDTWLLSNGFVSAEGRSILPTLAARAPSVVEQHLALMLYCFLETGLLNALVEVVVSSDQFVSVQATVLIGKILQLMHTHLPPDICCTSPALPTLVSHATLGNQQANAAVAALQNYQKLLRQRPASRSLFLDSIIQGGALIQTRLFRRHLNVQEQAGPVLQLQETAEAAAFAVPPVTQFRGTLDRSRLDSVSSSDESNSQASTSSRSSFRLKRKFLPQALYDNFRAFNRLLTDSRVLSQADAHLWDWDVITTILKSNLIRKLDYTQGKFLKRLVDFYKPRNNRFSHQDLVPGQRLPTYVSAGLDLIDVLLSSNELECMRFITDYFSDISQQLAAVTTSNRAHDCLFSPQHMNNTMCQQYFLYIGRMCRTVKGIEVLKNTTVFEYLINLVRVTDHVCYVKLIVSGLNYSYEKLPRQVLEKALTSAKTRGRLYSTQFMAVLLRARLPHFEVWGIPLIINQTRDSDRSVGLAAMDVLEEACHDKYYLEEIVSRWPNLTHRGDAGRLLMARYYSLPRGLNSTMARIEDEIRYWRNGYNKRYVLLVEADTHSSLTLHIRNEDGYYSRRNCNQRPQTVPPNVAPHLYGQMAQTGQGMTALRKHGDLPQLLELLRRAKCTDDAECLELKAAIWALAHASTHSNGIEYFVELNARLYEKLIVLVTKCEVYSVRATCFSALGLIAGTQAGANILFKLNWLSVRHDKNTMWPVHQPEDWMSSQYTPVRHYYEDVPADNMTMMDDYIERFYETGSDFWHMLADQTDASGGGGGVAGTVVGMHPIVQDPNATITTTDSVCTTTDDVHPRMLVGVAAKSKTLPEGSNLRQGKHQRSLSESKTTDVISLLGSGVGTMSGAVLYPTPYQHRIRYNSCTDSNTSGVSSCESVTGRTAAAYAAAANELQQFPLSPIPSMSNLLESDELFRRNQLATSMLPSTLSPMAMKGYVQLRSLRKHSRPVFSESSAEFYDFAEILDTPEVQMRKLDWTHSHRRLKVRSLDRQLSDVYRRLSADELNVLLPTLNAPKFLPPNDLKGPCYAGICLPKNVLDLFPTRNLSRTYVSRDIQDQDIVGINLLNTMLRPQCLNDSLTNEGGDESSVISSLSDVSSASRRQTRQLQQGAKHSRSLCLHCARSPRQQRNDSGSHSNGGGGASLAPCELYSSAAAALVAAGIQAGPVLAKKSGSSAQGASAALGADISFHSPESMLSEDSLPDRLTASILYNVQRLANPVSAKQSKMALLELKQKHPHAFQDICLYSEACKTIGRSSYRMIARRFLQELFLDLNFDSFYVEPQLIIGARKFSAEEKAEATAPTAMQAMPFKQTILKPKPAAQLASVYETSWENLLMDQSPRINKSSPADQPANAQTKAKARNQLHIDDTESSLSSTDGENDSGEDVCDGSGAGTQASSVTTAHTALPTGNSNRSSIGTCTASQLVPGAATSNSAGAGTSASDNASTSLKNENRQFTRGRFYTLELDLSCTKNKFPIKNRSQRTPTPPPIESLIESKPTVQTDVNTSALPIMQRTGGSNDSSSALRYSTVTKSLSASMARPVGSLYCEKRLQSSKSEAVLDEVAKARRASGGVGLTTVRDNS
InterPro domains: - IPR016024: Armadillo-type fold (homologous_superfamily) [87-1035]
- IPR028267: Rapamycin-insensitive companion of mTOR, N-terminal domain (domain) [60-440]
- IPR029451: Rapamycin-insensitive companion of mTOR, middle domain (domain) [580-800]
- IPR028268: Pianissimo family (family) [22-1653]
- IPR029453: Rapamycin-insensitive companion of mTOR, domain 4 (domain) [805-908]
- IPR029452: Rapamycin-insensitive companion of mTOR, domain 5 (domain) [976-1050]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0019207 (kinase regulator activity), GO:0008047 (enzyme activator activity), GO:0019209 (kinase activator activity), GO:0019887 (protein kinase regulator activity), GO:0030295 (protein kinase activator activity), GO:0043539 (protein serine/threonine kinase activator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0051641 (cellular localization), GO:0048856 (anatomical structure development), GO:0009653 (anatomical structure morphogenesis), GO:0042221 (response to chemical), GO:0051240 (positive regulation of multicellular organismal process), GO:0071840 (cellular component organization or biogenesis), GO:0051239 (regulation of multicellular organismal process), GO:0045927 (positive regulation of growth), GO:0050793 (regulation of developmental process), GO:0065008 (regulation of biological quality), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0048583 (regulation of response to stimulus), GO:0051716 (cellular response to stimulus), GO:0023051 (regulation of signaling), GO:0007165 (signal transduction), GO:0048869 (cellular developmental process), GO:0023056 (positive regulation of signaling), GO:0007275 (multicellular organism development), GO:0048584 (positive regulation of response to stimulus), GO:0019222 (regulation of metabolic process), GO:0033036 (macromolecule localization), GO:0009893 (positive regulation of metabolic process), GO:0006950 (response to stress), GO:0051094 (positive regulation of developmental process), GO:0007154 (cell communication), GO:0040008 (regulation of growth), GO:0048522 (positive regulation of cellular process), GO:0032989 (cellular component morphogenesis), GO:0044085 (cellular component biogenesis), GO:0048468 (cell development), GO:1900078 (positive regulation of cellular response to insulin stimulus), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0009966 (regulation of signal transduction), GO:0071495 (cellular response to endogenous stimulus), GO:0060255 (regulation of macromolecule metabolic process), GO:0050803 (regulation of synapse structure or activity), GO:0044089 (positive regulation of cellular component biogenesis), GO:0009725 (response to hormone), GO:0044087 (regulation of cellular component biogenesis), GO:0000902 (cell morphogenesis), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0016043 (cellular component organization), GO:0031668 (cellular response to extracellular stimulus), GO:0051128 (regulation of cellular component organization), GO:0051962 (positive regulation of nervous system development), GO:0071496 (cellular response to external stimulus), GO:0090066 (regulation of anatomical structure size), GO:0048638 (regulation of developmental growth), GO:0051173 (positive regulation of nitrogen compound metabolic process), GO:0048639 (positive regulation of developmental growth), GO:0009967 (positive regulation of signal transduction), GO:0050773 (regulation of dendrite development), GO:0035556 (intracellular signal transduction), GO:0010604 (positive regulation of macromolecule metabolic process), GO:1901700 (response to oxygen-containing compound), GO:0051130 (positive regulation of cellular component organization), GO:0010033 (response to organic substance), GO:0009891 (positive regulation of biosynthetic process), GO:0009991 (response to extracellular stimulus), GO:1900076 (regulation of cellular response to insulin stimulus), GO:2000026 (regulation of multicellular organismal development), GO:0042594 (response to starvation), GO:1901698 (response to nitrogen compound), GO:0010646 (regulation of cell communication), GO:0031325 (positive regulation of cellular metabolic process), GO:0016358 (dendrite development), GO:0070887 (cellular response to chemical stimulus), GO:0033554 (cellular response to stress), GO:0009889 (regulation of biosynthetic process), GO:0070727 (cellular macromolecule localization), GO:0010647 (positive regulation of cell communication), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:1901652 (response to peptide), GO:0032535 (regulation of cellular component size), GO:0030030 (cell projection organization), GO:0050807 (regulation of synapse organization), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0032990 (cell part morphogenesis), GO:0031929 (TOR signaling), GO:0010468 (regulation of gene expression), GO:0048666 (neuron development), GO:0022607 (cellular component assembly), GO:0000904 (cell morphogenesis involved in differentiation), GO:0007399 (nervous system development), GO:0031667 (response to nutrient levels), GO:1902533 (positive regulation of intracellular signal transduction), GO:0048813 (dendrite morphogenesis), GO:0008582 (regulation of synaptic assembly at neuromuscular junction), GO:0051252 (regulation of RNA metabolic process), GO:0048858 (cell projection morphogenesis), GO:1901701 (cellular response to oxygen-containing compound), GO:1901890 (positive regulation of cell junction assembly), GO:0071417 (cellular response to organonitrogen compound), GO:0046626 (regulation of insulin receptor signaling pathway), GO:0031344 (regulation of cell projection organization), GO:0071310 (cellular response to organic substance), GO:0009267 (cellular response to starvation), GO:1901888 (regulation of cell junction assembly), GO:0046628 (positive regulation of insulin receptor signaling pathway), GO:1901699 (cellular response to nitrogen compound), GO:0051960 (regulation of nervous system development), GO:1904398 (positive regulation of neuromuscular junction development), GO:0043434 (response to peptide hormone), GO:0010557 (positive regulation of macromolecule biosynthetic process), GO:0045935 (positive regulation of nucleobase-containing compound metabolic process), GO:0022008 (neurogenesis), GO:0051254 (positive regulation of RNA metabolic process), GO:0032870 (cellular response to hormone stimulus), GO:0010243 (response to organonitrogen compound), GO:0051965 (positive regulation of synapse assembly), GO:0031326 (regulation of cellular biosynthetic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0045887 (positive regulation of synaptic assembly at neuromuscular junction), GO:0008104 (protein localization), GO:0006996 (organelle organization), GO:0031669 (cellular response to nutrient levels), GO:0030182 (neuron differentiation), GO:0031328 (positive regulation of cellular biosynthetic process), GO:1902531 (regulation of intracellular signal transduction), GO:2001141 (regulation of RNA biosynthetic process), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0051897 (positive regulation of protein kinase B signaling), GO:1904396 (regulation of neuromuscular junction development), GO:0051963 (regulation of synapse assembly), GO:0051896 (regulation of protein kinase B signaling), GO:1902680 (positive regulation of RNA biosynthetic process), GO:0048699 (generation of neurons), GO:0070925 (organelle assembly), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0033365 (protein localization to organelle), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0071375 (cellular response to peptide hormone stimulus), GO:0032868 (response to insulin), GO:0120036 (plasma membrane bounded cell projection organization), GO:0006355 (regulation of DNA-templated transcription), GO:0008361 (regulation of cell size), GO:1901653 (cellular response to peptide), GO:0031175 (neuron projection development), GO:0034504 (protein localization to nucleus), GO:0045793 (positive regulation of cell size), GO:0032869 (cellular response to insulin stimulus), GO:0048812 (neuron projection morphogenesis), GO:1903508 (positive regulation of nucleic acid-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription), GO:0010975 (regulation of neuron projection development), GO:0045893 (positive regulation of DNA-templated transcription), GO:0140694 (non-membrane-bounded organelle assembly), GO:0034063 (stress granule assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0032991 (protein-containing complex), GO:0140535 (intracellular protein-containing complex), GO:0038201 (TOR complex), GO:0031932 (TORC2 complex)