Protein: Ribosome assembly factor mrt4 (Q7K1Q7)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|RuleBase:RU364039}. Nucleus, nucleolus {ECO:0000256|RuleBase:RU364039}.
Sequence: MPRSKRDKKVSLTKTDRKGLAWKQRIVDDIRFCVGKYPNIFVFQVQNMRNSLLKDLRQELKKNSRFIFGKNRVMQIGLGRTKSEEVEPELHKLSKRLTGQVGLLFTDKSKEEVLEWAENYWAVEYARSGFVATETVTLPAGPLEDFAHSMEPHLRSLGLPTKLEKGIVTLYSDYTVCEEGKVLTPEQARILKLVGKPMAKFRLTMKCSWTKSEGFQLHVEDDVNDEEQADSAMEEEAEAEAMDDNDDDDDEEEDDE
InterPro domains: - IPR043141: Large ribosomal subunit protein uL10-like domain superfamily (homologous_superfamily) [20-214]
- IPR040637: Large ribosomal subunit protein uL10-like, insertion domain (domain) [126-195]
- IPR051742: Ribosomal Assembly Factor uL10 (family) [1-214]
- IPR033867: Ribosome assembly factor Mrt4 (family) [21-184]
- IPR001790: Large ribosomal subunit protein uL10 (family) [20-120]
- IPR043164: Large ribosomal subunit protein uL10-like, insertion domain superfamily (homologous_superfamily) [125-198]
Interaction partners: - 60S ribosome subunit biogenesis protein NIP7 homolog
- Guanine nucleotide-binding protein-like 3 homolog
- Probable ribosome biogenesis protein RLP24
- Ribosome biogenesis protein NSA2 homolog
- Nucleolar GTP-binding protein 1
- Ribosome production factor 2 homolog
- Ribosome biogenesis protein BOP1 homolog
- Probable rRNA-processing protein EBP2 homolog
- Nucleolar complex protein 2
- Zinc finger protein 593 homolog
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0019843 (rRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0010467 (gene expression), GO:0042254 (ribosome biogenesis), GO:0042274 (ribosomal small subunit biogenesis), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0034470 (ncRNA processing), GO:0030490 (maturation of SSU-rRNA), GO:0006364 (rRNA processing), GO:0034660 (ncRNA metabolic process), GO:0016072 (rRNA metabolic process), GO:0000462 (maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA))
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)