Protein: E3 ubiquitin-protein ligase RDUF2 (EC 2.3.2.27) (RING and DUF1117 domain-containing protein 2) (AtRDUF2) (RING-type E3 ubiquitin transferase RDUF2) (Q940T5)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: E3 ubiquitin-protein ligase involved in the positive regulation of abscisic acid-dependent drought stress responses. Possesses E3 ubiquitin ligase activity in vitro.
Subcellular location: Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9SNB6}.
Sequence: MPSTPTTPTTTTPITASYWCYSCTRFVSVWADQGTTTVGSVACPHCDGGFIEQINDSSSAATELTIPASTEVRSINNNRRSVIRRRRSGRRPSFNPVIVLQGGAGEREEGEEGDAARDRRAFEFYYDDGSGSGLRPLPDSVSEILMGSGFERLLEQLSQIEASATGIGRSGNPPASKSAIESLPRVEISDCHIGSEANCAVCTEIFETETEAREMPCKHLFHDDCIVPWLSIRNSCPVCRFELPSEPNRRSNNNEEDNAVGMTIWRLPGGGFAVGRFNAAMRDGERVLPVVLTEMDGGGIGNSQDGPRRISWVRSHGTLESDSNGTGSGSGSGGRLRRMVRGMVSLMRRVRPNRSSSSSSAAISTSSDNLDLNIEVESRVLDRSNSVMRRYFRRNRSNRDSSSSVLH
InterPro domains: - IPR013083: Zinc finger, RING/FYVE/PHD-type (homologous_superfamily) [164-246]
- IPR039525: E3 ubiquitin-protein ligase RNF126-like, zinc-ribbon (domain) [17-54]
- IPR010543: Domain of unknown function DUF1117 (domain) [260-391]
- IPR001841: Zinc finger, RING-type (domain) [198-240]
Interaction partners: - NEP1-interacting protein-like 1
- Elongation factor G, putative
- AT3g59080/F17J16_130
- Eukaryotic aspartyl protease family protein
- Aspartic proteinase Asp1
- Aspartic proteinase Asp1
- At3g50050
- Eukaryotic aspartyl protease family protein
- Eukaryotic aspartyl protease family protein
- Eukaryotic aspartyl protease family protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0019787 (ubiquitin-like protein transferase activity), GO:0004842 (ubiquitin-protein transferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0009628 (response to abiotic stimulus), GO:0006950 (response to stress), GO:0042221 (response to chemical), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0009719 (response to endogenous stimulus), GO:0044238 (primary metabolic process), GO:0001101 (response to acid chemical), GO:1901700 (response to oxygen-containing compound), GO:0009414 (response to water deprivation), GO:0010035 (response to inorganic substance), GO:0009415 (response to water), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:1902074 (response to salt), GO:0036211 (protein modification process), GO:0097305 (response to alcohol), GO:0009737 (response to abscisic acid), GO:0043412 (macromolecule modification), GO:0033993 (response to lipid), GO:0070647 (protein modification by small protein conjugation or removal), GO:0032446 (protein modification by small protein conjugation), GO:0016567 (protein ubiquitination), GO:0051865 (protein autoubiquitination)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)