wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: ADP-ribosylglycohydrolase (Q382Z4)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MVAKLQHNPAPTTLNFYEKSFQQLSDVQQRQTGLLIGAAVGDAAARALDGYTAEEVAAVAAESGSLQDEDEDPVVFASVTPREHKSGLLRHHSYTFYLFSQLLRVMATSRGDFPVQYVKNEWVATARAHPDCFVREHASLLHVLCITMQLPVIYPWADDSTLREYASDFLEFLTETPAERAVASREDVYAYTNSVLGVALRCLQSNPDPYRNAAFMAAPGTAHVFPDDLALYCPPALVGSSHSRTEELSEADSKTVPLFPARLLESDVRVVRECLVVARGAASFAEGIKAAIHLGGPVCQRSLIVGALLGARMGVRRIPISWLSATYDHVPLVTLALQVAQWSWNPPHH
InterPro domains: - IPR036705: ADP-ribosylation/Crystallin J1 superfamily (homologous_superfamily) [26-345]
- IPR050792: ADP-ribosylglycohydrolase (family) [25-349]
Interaction partners: - Uncharacterized protein
- Mitochondrial ribosomal protein S18
- Small ribosomal subunit protein uS5 C-terminal domain-containing protein
- Uncharacterized protein
- Uncharacterized protein
- Dehydrogenase-like protein
- PROP1-like PPR domain-containing protein
- Uncharacterized protein
- Uncharacterized protein
- Uncharacterized protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0008233 (peptidase activity), GO:0004175 (endopeptidase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071704 (organic substance metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0036211 (protein modification process), GO:0043412 (macromolecule modification), GO:0018193 (peptidyl-amino acid modification), GO:0070647 (protein modification by small protein conjugation or removal), GO:0018205 (peptidyl-lysine modification), GO:0032446 (protein modification by small protein conjugation), GO:0016925 (protein sumoylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0005739 (mitochondrion), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Interleukin (Q7T110)
Organism: Gallus gallus (Chicken)
Function: Not known
Subcellular location: Secreted {ECO:0000256|ARBA:ARBA00004613}.
Sequence: MMCKVLIFGCISVAMLMTTAYGASLSSAKRKPLQTLIKDLEILENIKNKIHLELYTPTETQECTQQTLQCYLGEVVTLKKETEDDTEIKEEFVTAIQNIEKNLKSLTGLNHTGSECKICGANNKKKFPDFLHELTNFVRYLQK
InterPro domains: - IPR003443: Interleukin-15/Interleukin-21 family (family) [3-142]
- IPR009079: Four-helical cytokine-like, core (homologous_superfamily) [26-143]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (signaling receptor activator activity), GO:0048018 (receptor ligand activity), GO:0005125 (cytokine activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0002376 (immune system process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0001775 (cell activation), GO:0045321 (leukocyte activation), GO:0019222 (regulation of metabolic process), GO:0051240 (positive regulation of multicellular organismal process), GO:0002684 (positive regulation of immune system process), GO:0050794 (regulation of cellular process), GO:0009893 (positive regulation of metabolic process), GO:0002682 (regulation of immune system process), GO:0051239 (regulation of multicellular organismal process), GO:0048522 (positive regulation of cellular process), GO:0002696 (positive regulation of leukocyte activation), GO:0042127 (regulation of cell population proliferation), GO:0010604 (positive regulation of macromolecule metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0002694 (regulation of leukocyte activation), GO:0050865 (regulation of cell activation), GO:0046649 (lymphocyte activation), GO:0050867 (positive regulation of cell activation), GO:0008284 (positive regulation of cell population proliferation), GO:0051251 (positive regulation of lymphocyte activation), GO:0042110 (T cell activation), GO:0010628 (positive regulation of gene expression), GO:0070665 (positive regulation of leukocyte proliferation), GO:0070663 (regulation of leukocyte proliferation), GO:0010468 (regulation of gene expression), GO:0051249 (regulation of lymphocyte activation), GO:0032946 (positive regulation of mononuclear cell proliferation), GO:0050670 (regulation of lymphocyte proliferation), GO:0032944 (regulation of mononuclear cell proliferation), GO:0046631 (alpha-beta T cell activation), GO:0050671 (positive regulation of lymphocyte proliferation), GO:0036037 (CD8-positive, alpha-beta T cell activation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005576 (extracellular region), GO:0005615 (extracellular space)
Protein: Vacuolar protein sorting-associated protein 20 homolog 1 (AtVPS20-1) (Charged multivesicular body protein 6 homolog 1) (ESCRT-III complex subunit VPS20 homolog 1) (Q8GXN6)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-III complex is probably involved in the concentration of MVB cargo (By similarity).
Subcellular location: Endosome {ECO:0000250}.
Sequence: MGNLFVKKPQITEVDRAILSLKTQRRKLGQYQQKLEKVIEAEKQAARDLIREKRKDRALLALRKKRTQEELLKQVDQWVINVEQQLTDIELTSKQKAVFESLKQGNSAIKAIQSELDLDDVQKLMDDTADAKAYQDELNAILGEKLSAEDEEDILAEFDNLESQLIVDEMPEVPTKESEESEKLDLPDVPTKTPVASNAEITPAESATKTKVLEEPLPA
InterPro domains: - IPR005024: Snf7 family (family) [10-196]
Interaction partners: - Vacuolar protein sorting-associated protein 36
- Vacuolar protein sorting-associated protein 32 homolog 2
- Vacuolar protein sorting-associated protein 32 homolog 1
- Vacuolar protein sorting-associated protein 2 homolog 1
- Putative vacuolar protein sorting-associated protein 22 homolog 2
- Vacuolar protein sorting-associated protein 22 homolog 1
- Protein ELC
- Vacuolar protein sorting-associated protein 24 homolog 1
- Protein SUPPRESSOR OF K
- Putative vacuolar protein sorting-associated protein 24 homolog 2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0006810 (transport), GO:0006996 (organelle organization), GO:0010256 (endomembrane system organization), GO:0016192 (vesicle-mediated transport), GO:0061024 (membrane organization), GO:0006900 (vesicle budding from membrane), GO:0007032 (endosome organization), GO:0016050 (vesicle organization)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0005829 (cytosol), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0031982 (vesicle), GO:0005770 (late endosome), GO:0097708 (intracellular vesicle)
Protein: Proline-rich membrane anchor 1 (PRiMA) (Q810F0)
Organism: Mus musculus (Mouse)
Function: Required to anchor acetylcholinesterase (ACHE) to the basal lamina of the neuromuscular junction and to the membrane of neuronal synapses in brain. Also able to organize ACHE into tetramers.
Subcellular location: Cell membrane; Single-pass type I membrane protein. Cell junction. Synapse. Note=In the brain, PRIMA linked to ACHE is found in membrane rafts.
Sequence: MLLRDLVPRHGCCWPSLLLHCALHPLWGLVQVTHAEPQKSCSKVTDSCQHICQCRPPPPLPPPPPPPPPPRLLSAPAPNSTSCPAEDSWWSGLVIIVAVVCASLVFLTVLVIICYKAIKRKPLRKDENGTSVAEYPMSSSQSHKGVDVNAAVV
InterPro domains: - IPR029659: Proline-rich membrane anchor 1 (family) [1-153]
Interaction partners: - Acetylcholinesterase collagenic tail peptide
- Cellular tumor antigen p53
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0050793 (regulation of developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0050794 (regulation of cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0051128 (regulation of cellular component organization), GO:0032989 (cellular component morphogenesis), GO:0000902 (cell morphogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0016358 (dendrite development), GO:0048731 (system development), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0016043 (cellular component organization), GO:0051128 (regulation of cellular component organization), GO:0022008 (neurogenesis), GO:0022604 (regulation of cell morphogenesis), GO:0000904 (cell morphogenesis involved in differentiation), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0031344 (regulation of cell projection organization), GO:0032990 (cell part morphogenesis), GO:0048813 (dendrite morphogenesis), GO:0048858 (cell projection morphogenesis), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0048667 (cell morphogenesis involved in neuron differentiation), GO:0120035 (regulation of plasma membrane bounded cell projection organization), GO:0031175 (neuron projection development), GO:0048699 (generation of neurons), GO:0120039 (plasma membrane bounded cell projection morphogenesis), GO:0120036 (plasma membrane bounded cell projection organization), GO:0048812 (neuron projection morphogenesis), GO:0010975 (regulation of neuron projection development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: non-specific serine/threonine protein kinase (EC 2.7.11.1) (Q38ES8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MGRPFRIVQRLSEKVLNPEAKSSKKSSKKAKDVYSYIVVVENIEALPMFARYVVVKRTFFKIDEVLLAHREPEILNRVRDKGILHVFHSEVTRNDGRLGTTVAMEYCPGSLEQRLQQETRMLESEVVQVLLALASVLGYLHSRQPPVAHRNINPSNVLIHSESAGASAYRLYNFRSAMTEAYHCENHEEVVAAMEDFARYTTAGYRAPEMLDPSSHKRIDEQVDMWALGVLLYYTMYQRLPFTDACWGLARKPKLRYPVEAEVWYTGSLRIVLEHLLEPDPEKRWDAFALINFMRFDNDLCRHIGPFCFSQTERPEGWEPQDVKVIGRPVPAKVLPERLRNTGQSDDPAAAARDNRDEAAATSVKSRTAAQESGDNDQMVLKAVTALSSDTASTDPEVLAYREKLIREQEEAWQVAESAHKKRDKEDKDGATSGPADVDSLFGPTEKKEAVKENKASAIDDLFGGMETQPSQSQKPTTDDLFGGASTATASNQIPPQGSQVGANDSWKDDLFAAPPQQPQMQPQPAFPMAADSSWSTGAPTSVPMNPTGGMMGQQQAPMGWGNGVTAPGFQPMQTPQMQQQVPGGWGNGATASGFQPMQTPQMQQQVPGGWGNGATAPSFQPMQTPQMQQQVPGGWGNGATAPGFQPMQTPQMQQQVPGGAPGFMGGNDLFQRPQQQQPQQPEKDPFASLFK
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [51-302]
- IPR000719: Protein kinase domain (domain) [5-296]
Interaction partners: - Clathrin coat assembly protein, putative
- Clathrin heavy chain
- ADF-H domain-containing protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:1901564 (organonitrogen compound metabolic process), GO:0019538 (protein metabolic process), GO:0043170 (macromolecule metabolic process), GO:0006793 (phosphorus metabolic process), GO:0036211 (protein modification process), GO:0006796 (phosphate-containing compound metabolic process), GO:0043412 (macromolecule modification), GO:0006468 (protein phosphorylation), GO:0016310 (phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0005737 (cytoplasm), GO:0031974 (membrane-enclosed lumen), GO:0043233 (organelle lumen), GO:0120025 (plasma membrane bounded cell projection), GO:0043229 (intracellular organelle), GO:0099568 (cytoplasmic region), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005929 (cilium), GO:0032838 (plasma membrane bounded cell projection cytoplasm), GO:0070013 (intracellular organelle lumen), GO:0031981 (nuclear lumen), GO:0097014 (ciliary plasm), GO:0005634 (nucleus)
Protein: Cysteine-rich hydrophobic domain-containing protein 2 (Q9D9G3)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Golgi apparatus {ECO:0000250}. Note=Associated and found in vesicular structures of Golgi complex. {ECO:0000250}.
Sequence: MADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLRKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLEWENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD
InterPro domains: - IPR019383: Golgin subfamily A member 7/ERF4 (domain) [45-134]
- IPR039735: Cysteine-rich hydrophobic domain-containing protein 1/2 (family) [1-165]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0009887 (animal organ morphogenesis), GO:0009888 (tissue development), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0007507 (heart development), GO:0055006 (cardiac cell development), GO:0003007 (heart morphogenesis), GO:0060485 (mesenchyme development), GO:0048762 (mesenchymal cell differentiation), GO:0035051 (cardiocyte differentiation), GO:0072359 (circulatory system development), GO:0060317 (cardiac epithelial to mesenchymal transition), GO:0001837 (epithelial to mesenchymal transition)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: (Z)-3-hexen-1-ol acetyltransferase (EC 2.3.1.195) (Q9SRQ2)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acyltransferase involved in the production of green leaf volatiles (GLVs). Uses acetyl-CoA as substrate, but not malonyl-CoA or benzoyl-CoA. Prefers primary, medium-chain-length, aliphatic alcohols.
Sequence: MDHQVSLPQSTTTGLSFKVHRQQRELVTPAKPTPRELKPLSDIDDQQGLRFQIPVIFFYRPNLSSDLDPVQVIKKALADALVYYYPFAGRLRELSNRKLAVDCTGEGVLFIEAEADVALAELEEADALLPPFPFLEELLFDVEGSSDVLNTPLLLVQVTRLKCCGFIFALRFNHTMTDGAGLSLFLKSLCELACGLHAPSVPPVWNRHLLTVSASEARVTHTHREYDDQVGIDVVATGHPLVSRSFFFRAEEISAIRKLLPPDLHNTSFEALSSFLWRCRTIALNPDPNTEMRLTCIINSRSKLRNPPLEPGYYGNVFVIPAAIATARDLIEKPLEFALRLIQETKSSVTEDYVRSVTALMATRGRPMFVASGNYIISDLRHFDLGKIDFGPWGKPVYGGTAKAGIALFPGVSFYVPFKNKKGETGTVVAISLPVRAMETFVAELNGVLNVSKG
InterPro domains: - IPR050898: Plant acyltransferase (family) [16-445]
- IPR023213: Chloramphenicol acetyltransferase-like domain superfamily (homologous_superfamily) [14-443]
Interaction partners: - Alcohol dehydrogenase class-P
- NAC domain-containing protein 6
- Zinc knuckle
- Putative GEM-like protein 8
- Mitochondrial import inner membrane translocase subunit TIM23-3
- Kinectin-like protein
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016410 (N-acyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0019748 (secondary metabolic process), GO:0071704 (organic substance metabolic process), GO:0044550 (secondary metabolite biosynthetic process), GO:0044249 (cellular biosynthetic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0009698 (phenylpropanoid metabolic process), GO:1901362 (organic cyclic compound biosynthetic process), GO:0019438 (aromatic compound biosynthetic process), GO:0009699 (phenylpropanoid biosynthetic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0009536 (plastid), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Uncharacterized transporter SLY41 (P22215)
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Function: Able to suppress the functional loss of YPT1. May form a channel. Protein SLY41 is not essential for cell viability. The SLY41 gene is a multicopy suppressor.
Subcellular location: Membrane; Multi-pass membrane protein.
Sequence: MIQTQSTAIKRRNSVHKNLFDPSLYQIPEPPRGGFQHQKKEYSKETFSNQVFGYDITSLKKRFTQLFPSNIQGYLPEVDLRITIICSIWYVTSSISSNLSKAILRTFNHPIALTELQFLVSAVLCVGFASIVNLFRLPRLKHTKFSKALNSFPDGILPEYLDGNFRSSILHKFLVPSKLVLMTTFPMGIFQFIGHITSHKAVSMIPVSLVHSVKALSPIITVGYYKFFEHRYYNSMTYYTLLLLIFGVMTTCWSTHGSKRASDNKSGSSLIGLLFAFISMIIFVAQNIFAKNILTIRRKVGILPSSSTDDVTSKEGQPSLDKTRFSPLQVDKITILFYCSCIGFSLTLLPFLTGELMHGGSVINDLTLETVALVAIHGIAHFFQAMLAFQLIGLLSSINYSVANIMKRIVVISVALFWETKLNFFQVFGVILTIAGLYGYDKWGLSKKDGRQA
InterPro domains: - IPR004696: Triose phosphate/phosphoenolpyruvate translocator (family) [113-451]
- IPR050186: Triose Phosphate/Phosphate Translocator (family) [83-441]
- IPR004853: Sugar phosphate transporter domain (domain) [178-440]
Interaction partners: - GTP-binding protein YPT1
- Intracellular protein transport protein USO1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015605 (organophosphate ester transmembrane transporter activity), GO:0008514 (organic anion transmembrane transporter activity), GO:0015932 (nucleobase-containing compound transmembrane transporter activity), GO:1901505 (carbohydrate derivative transmembrane transporter activity), GO:0015215 (nucleotide transmembrane transporter activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0055085 (transmembrane transport), GO:0015780 (nucleotide-sugar transmembrane transport), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0071705 (nitrogen compound transport), GO:0015931 (nucleobase-containing compound transport), GO:1901264 (carbohydrate derivative transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043229 (intracellular organelle), GO:0005783 (endoplasmic reticulum), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle)
Protein: Variant surface glycoprotein (VSG), putative (Q57TR3)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004609}; Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}.
Sequence: MHTIFPAALLAGYVVAFVAADATNTLAHDSTLWCHDIQYLEAILAAIDKEMNNRQKQLQVDAELIAKWKLAEAAAEQWHERRKYTALSVVIATLASKNSEAATEYLSAAAEAKKAINRRLEALQLVARTTSALKQTVTGAPQAASANAACQGSTEYASEAEFTCAPPEAGELKTAEVQTKLHTATHIKLTSFKALNELVAAPKITITATAGTTPFASPGQTPGTCQTSGGQNIAAGTNHVQYAVSSATVLKTQTPAAQPIDSDSERPEEPTAKKATVTAWLDIKFVTAALKNLKTAYNQKQIDLSQATHSTLAGLAGFKTVIANLFVGAEPPANNQETEYNNKIADIIKQTYGPEPGDFKRKFVTELANQDVKYTKAGNEQEKKLGALSKGADLSIALSFIINKRHESQLQKAAKAVSTVPKQNCTGKTKEKCKDACEWKGTDDKGECKPKDEEGQTNAAGTQGAETEGKDDKNNTNTTGSNSFVIHKAPLLLAVFVSIIYFLKISAQF
InterPro domains: - IPR027446: Variant surface glycoprotein C-terminal domain superfamily (homologous_superfamily) [403-485]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0046812 (host cell surface binding), GO:0046789 (host cell surface receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to external stimulus), GO:0044403 (biological process involved in symbiotic interaction), GO:0051707 (response to other organism), GO:0009607 (response to biotic stimulus), GO:0051701 (biological process involved in interaction with host), GO:0075136 (response to host), GO:0043207 (response to external biotic stimulus), GO:0052173 (response to defenses of other organism), GO:0052200 (response to host defenses), GO:0052572 (response to host immune response), GO:0042783 (evasion of host immune response), GO:0020033 (antigenic variation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)