wanglab/bioreason-pro-rl-reasoning-data huggingface dataset:
Protein: Sm protein F (Q570S3)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR006609}.
Sequence: MEYKGFLASVDSYMNLQLGNTEEYIDGQLTGNLGEILIRCNNVLYVRGVPEDEELEDADQD
InterPro domains: - IPR016487: Sm-like protein Lsm6/SmF (family) [1-52]
- IPR047575: Sm domain (domain) [1-52]
- IPR010920: LSM domain superfamily (homologous_superfamily) [2-50]
- IPR034100: Small nuclear ribonucleoprotein F (family) [1-48]
- IPR001163: Sm domain, eukaryotic/archaea-type (domain) [1-48]
Interaction partners: - Small nuclear ribonucleoprotein Sm D2
- Small nuclear ribonucleoprotein SmD1b
- Small nuclear ribonucleoprotein E
- Small nuclear ribonucleoprotein SmD1a
- Small nuclear ribonucleoprotein SmD3b
- Probable small nuclear ribonucleoprotein G
- Small nuclear ribonucleoprotein E
- Small nuclear ribonucleoprotein G
- Small nuclear ribonucleoprotein SmD3a
- Sm-like protein LSM2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0010035 (response to inorganic substance), GO:0010038 (response to metal ion), GO:0010043 (response to zinc ion)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0032991 (protein-containing complex), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0120114 (Sm-like protein family complex), GO:0043229 (intracellular organelle), GO:0120115 (Lsm2-8 complex), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Probable serine/threonine-protein kinase CST (EC 2.7.11.1) (Protein CAST AWAY) (P27450)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as a spatial inhibitor of signaling that modulates abscission zone cell adhesion and expansion. Acts both directly and indirectly by physically interacting with RLK5/HAE and SOBIR1/EVR at the cell surface.
Subcellular location: Cell membrane {ECO:0000269|PubMed:21219905, ECO:0000269|PubMed:21628627}; Lipid-anchor {ECO:0000269|PubMed:21628627, ECO:0000305|PubMed:21219905}. Nucleus {ECO:0000269|PubMed:21219905}. Note=Predominantly localized at the plasma membrane. {ECO:0000269|PubMed:21219905}.
Sequence: MGACISFFSSSSPSKTGLHSHATTNNHSNGTEFSSTTGATTNSSVGQQSQFSDISTGIISDSGKLLESPNLKVYNFLDLKTATKNFKPDSMLGQGGFGKVYRGWVDATTLAPSRVGSGMIVAIKRLNSESVQGFAEWRSEVNFLGMLSHRNLVKLLGYCREDKELLLVYEFMPKGSLESHLFRRNDPFPWDLRIKIVIGAARGLAFLHSLQREVIYRDFKASNILLDSNYDAKLSDFGLAKLGPADEKSHVTTRIMGTYGYAAPEYMATGHLYVKSDVFAFGVVLLEIMTGLTAHNTKRPRGQESLVDWLRPELSNKHRVKQIMDKGIKGQYTTKVATEMARITLSCIEPDPKNRPHMKEVVEVLEHIQGLNVVPNRSSTKQAVANSSRSSPHHYRYKAGALGAERKRATPGRFGSVEK
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [71-383]
- IPR008271: Serine/threonine-protein kinase, active site (active_site) [214-226]
- IPR001245: Serine-threonine/tyrosine-protein kinase, catalytic domain (domain) [89-365]
- IPR017441: Protein kinase, ATP binding site (binding_site) [92-124]
- IPR000719: Protein kinase domain (domain) [86-368]
- IPR050823: Plant Serine/Threonine-Protein Kinase (family) [39-369]
Interaction partners: - Putative B3 domain-containing protein At3g28853
- B3 domain-containing protein At1g10455
- Kinesin-like protein KIN-14G
- Kinesin-like protein KIN-4A
- Kinesin-like protein KIN-14N
- Kinesin-like protein KIN-12B
- Phosphatidylglycerophosphate phosphatase PTPMT1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032501 (multicellular organismal process), GO:0032502 (developmental process), GO:0007275 (multicellular organism development), GO:0048856 (anatomical structure development), GO:0009838 (abscission)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: C-type lectin domain family 4, member a4 (Dendritic cell inhibitory receptor 2) (Q5YIR8)
Organism: Mus musculus (Mouse)
Function: Not known
Sequence: MASEITYAEVRITNESDSLDTYSKCPAAPREKPIRDLRKPGSPSLLLTSLMLLLLLLAITFLVAFIIYFQKYSQLLEEKEAAKNIMYKELNCIKNGSLMEDKVWSCCPKDWKPFVSHCYFILNDSKASWNESEEKCSHMGAHLVVIHSQAEQDFITSNLNTSAGYFIGLLDAGQRQWRWIDQTPYNKSATFWHKGEPNQDWERCVIINHKTTGWGWNDIPCKDEHNSVCQVKKIYL
InterPro domains: - IPR033989: CD209-like, C-type lectin-like domain (domain) [107-230]
- IPR016186: C-type lectin-like/link domain superfamily (homologous_superfamily) [91-236]
- IPR018378: C-type lectin, conserved site (conserved_site) [204-229]
- IPR050111: C-type lectin and snaclec domain-containing protein (family) [61-233]
- IPR016187: C-type lectin fold (homologous_superfamily) [86-233]
- IPR001304: C-type lectin-like (domain) [107-230]
Interaction partners: - Lymphocyte antigen 75
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0030246 (carbohydrate binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0051716 (cellular response to stimulus), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0050794 (regulation of cellular process), GO:0007166 (cell surface receptor signaling pathway)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)
Protein: Large ribosomal subunit protein uL30 (60S ribosomal protein L7) (Q6Q417)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
Sequence: MAGETKKKIPSVPESLLKRRQRFAAIRAVRLKKAKADKKASKVTRKLIFKRAEAYHKEYKQLYRREIRMSRMARKAGNYYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGVFVKLNKASINMLRIAEPYIAWGYPNLKSVRELIYKRGFGKIKKQRIALTDNSLIEKTLGQCGIICIEDLIHEIYTVGKNFKAANNFLWPFKLSSPRGGMNKKTTHFVEGGDAGNREDQINRLVRRMN
InterPro domains: - IPR039699: Large ribosomal subunit protein uL30 (family) [6-246]
- IPR036919: Large ribosomal subunit protein uL30, ferredoxin-like fold domain superfamily (homologous_superfamily) [87-246]
- IPR016082: Large ribosomal subunit protein uL30-like, ferredoxin-like fold domain (domain) [88-138]
- IPR018038: Large ribosomal subunit protein uL30, conserved site (conserved_site) [106-138]
- IPR005998: Large ribosomal subunit protein uL30, eukaryotic (family) [13-246]
- IPR035808: Large ribosomal subunit protein uL30, eukaryotic/archaeal (domain) [87-246]
- IPR012988: Large ribosomal subunit protein uL30, N-terminal, eukaryotes (domain) [12-83]
Interaction partners: - Large ribosomal subunit protein eL6
- Small ribosomal subunit protein uS4
- Large ribosomal subunit protein uL29
- Small ribosomal subunit protein uS14
- Large ribosomal subunit protein uL2
- Ribosomal protein L3
- Large ribosomal subunit protein eL21
- FAU ubiquitin-like and ribosomal protein S30 fusion a ubiquitously expressed
- Large ribosomal subunit protein eL19
- 40S ribosomal protein S15
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0003735 (structural constituent of ribosome)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0001525 (angiogenesis), GO:0035295 (tube development), GO:0001568 (blood vessel development), GO:0048731 (system development), GO:0035239 (tube morphogenesis), GO:0048514 (blood vessel morphogenesis), GO:0001944 (vasculature development), GO:0072359 (circulatory system development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0031974 (membrane-enclosed lumen), GO:0043229 (intracellular organelle), GO:0043233 (organelle lumen), GO:0043227 (membrane-bounded organelle), GO:0043228 (non-membrane-bounded organelle), GO:0070013 (intracellular organelle lumen), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0031981 (nuclear lumen), GO:0005730 (nucleolus), GO:0005634 (nucleus)
Protein: LD10379p (Q7YU00)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Sequence: MSSSCERIEWVEIIEPRTKEHMYANLTTGECVWDPPEDVPIKRTDSSQWWELFDTNTQRFYYYNAATQKTVWHRPSKCDIIPLAKLQTLKQNTDPSERREQTTPQKQQQQQVQHASQQQQHPSPMSGPNKKGRGQQRISGGNGTVASSEEKLTSSEVISSPRGRQSFRVSTGDSSRSMDMQQQHPQGYASRRSQDSCNQYKESGKSSDSSLSSAHGYRRFNDSGVPVSGHPDNLRLGSLQKQQRGGGKDNGAFEMLQESTSSHNLPHGSTSTSSSYAGGSGYGDKYFDHQLLPNHLQGYSSKSSDIASPTHSIHTPQSQKKKMSPDAAPAAQYNYAQQQHQQRSAQRSGGGAAGTGAPAGKSYGGDREYKVSLARSGSFMSSSINPAAAGHHSKSYRKSSAEAANGGAASDDSMHEKYFKSVENTPLSRRRHTTNATKSGGGASGSNTATSTAGSGSSSHKKHSSDSSPQSPISPQTKSSRQAKTSATSTVPQLQHSPRLQEPSHSLDLLSLERISLGKSGPISPGGGTENLGLLTHSSRGSNDSARQRQKSNNSSANRSQSHHYPGQSSLRHSASSSLDKRGYHVGGGSGDGRGVTGGEKRRSKQHHYQQQADNSDVEYDNGNTSPLYTNWDQEMPHLLPLKHYIIEQAKLSGRYEYRGGDGGDSDSYHSDSQSEHSLSGHEPDNEDSDGGSDTHGGYLEHNYGMIDDYANMGDSVSYYAYMYPPHDPAGREDISENVEAVLEGIGGNATEPSAPTATAPKPKPRYQISYYDTVSHSPSAGSGYHGQQLYSNTPPYSGARSWTSRSTAVTAPPAAVAPGTERH
InterPro domains: - IPR036020: WW domain superfamily (homologous_superfamily) [42-76]
- IPR001202: WW domain (domain) [50-77]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0008047 (enzyme activator activity), GO:0060589 (nucleoside-triphosphatase regulator activity), GO:0030695 (GTPase regulator activity), GO:0005096 (GTPase activator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0071840 (cellular component organization or biogenesis), GO:0003008 (system process), GO:0007610 (behavior), GO:0016043 (cellular component organization), GO:0050877 (nervous system process), GO:0034330 (cell junction organization), GO:0007600 (sensory perception), GO:0050808 (synapse organization), GO:0050954 (sensory perception of mechanical stimulus), GO:0050975 (sensory perception of touch), GO:0007605 (sensory perception of sound)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0005737 (cytoplasm)
Protein: Dof zinc finger protein DOF5.4 (AtDOF5.4) (OBF-binding protein 4) (Q8LDR0)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence. Enhances the DNA binding of OBF transcription factors to OCS elements (By similarity).
Subcellular location: Nucleus {ECO:0000305}.
Sequence: MQDIHDFSMNGVGGGGGGGGRFFGGGIGGGGGGDRRMRAHQNNILNHHQSLKCPRCNSLNTKFCYYNNYNLSQPRHFCKNCRRYWTKGGVLRNVPVGGGCRKAKRSKTKQVPSSSSADKPTTTQDDHHVEEKSSTGSHSSSESSSLTASNSTTVAAVSVTAAAEVASSVIPGFDMPNMKIYGNGIEWSTLLGQGSSAGGVFSEIGGFPAVSAIETTPFGFGGKFVNQDDHLKLEGETVQQQQFGDRTAQVEFQGRSSDPNMGFEPLDWGSGGGDQTLFDLTSTVDHAYWSQSQWTSSDQDQSGLYLP
InterPro domains: - IPR045174: Dof zinc finger protein (family) [43-195]
- IPR003851: Zinc finger, Dof-type (domain) [49-105]
Interaction partners: - Protein AUXIN SIGNALING F-BOX 3
- Transcription factor RSL2
- Transcription factor TGA4
- Xyloglucan endotransglucosylase/hydrolase protein 9
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (sequence-specific DNA binding), GO:0000976 (transcription cis-regulatory region binding), GO:1990837 (sequence-specific double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0019222 (regulation of metabolic process), GO:0050794 (regulation of cellular process), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:0009889 (regulation of biosynthetic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0019219 (regulation of nucleobase-containing compound metabolic process), GO:0051252 (regulation of RNA metabolic process), GO:0010556 (regulation of macromolecule biosynthetic process), GO:0010468 (regulation of gene expression), GO:0031326 (regulation of cellular biosynthetic process), GO:2001141 (regulation of RNA biosynthetic process), GO:0006355 (regulation of DNA-templated transcription), GO:1903506 (regulation of nucleic acid-templated transcription)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)
Protein: Cadherin-related neural recepter 5 (O88192)
Organism: Mus musculus (Mouse)
Function: Not known
Subcellular location: Cell membrane {ECO:0000256|ARBA:ARBA00004251}; Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
Sequence: FSSKHGTFVGRIAQDLGLELTELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSLECSIHLEVIVDRPLQVFHVEVEVRDINDNPPVFPETNKNIVIAESRPPETRFPLDGASDADIGVNSALTYRLDPSDYFALDTQNNRERTSSLSLVLKKSLDREEIQEYSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFDRFVYKVKVLEDALNGTLVINLNATDPDEGINGDIIYSFRRPVSPAVVHAFNIDSNSGEVRTKGLLDFEEIKLYEIPVEAVDKGNIPMTGHCTLLVELLDVNDNAPEVTITSLSLPVREDAQPSTVIALVSVSDRDSGDNGQVTCSLTPHLPFKLVSTFKNYYSLVLDSALDRETTADYKVVVTARDRGSPSLWSTASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGAHIFTVSAMDADAQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLQFQVSARDAGVPSLGSNVTLQVFVLDENDNAPTLLPHRAVGAVGTVSELVPRSVGSGHVVAKVRAVDADSGYNAWLSYELQLAAGGMRSPFRVGLYTGEISTTRSLDEADAPRQRLLVLVKDHGEPALTATATVLVSLVENGQAPKISSLASESTASSEASLVTVNVYLIIAICAVSSLLVITLLLYTALRCSARSTDGACAPGKPMLVCSSAVGSWSYSQQRRQRVCSGEGPPKTDLMAFSPSLPPVLGSAEDTCQRERQVEHLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPANNQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
InterPro domains: - IPR050174: Protocadherin/Cadherin-related Cell Adhesion (family) [4-740]
- IPR002126: Cadherin-like (domain) [9-642]
- IPR031904: Cadherin, C-terminal catenin-binding domain (domain) [764-897]
- IPR013164: Cadherin, N-terminal (domain) [4-75]
- IPR015919: Cadherin-like superfamily (homologous_superfamily) [91-633]
- IPR020894: Cadherin conserved site (conserved_site) [194-527]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0005509 (calcium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhesion), GO:0098609 (cell-cell adhesion), GO:0098742 (cell-cell adhesion via plasma-membrane adhesion molecules), GO:0007156 (homophilic cell adhesion via plasma membrane adhesion molecules)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)
Protein: Putative inactive receptor-like protein kinase At1g64210 (Q9SH71)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Not known
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Sequence: MQIFLFFFSLILCFVLISSQTLEDDKKALLHFLSSFNSSRLHWNQSSDVCHSWTGVTCNENGDRIVSVRLPAVGFNGLIPPFTISRLSSLKFLSLRKNHFTGDFPSDFTNLKSLTHLYLQHNHLSGPLLAIFSELKNLKVLDLSNNGFNGSIPTSLSGLTSLQVLNLANNSFSGEIPNLHLPKLSQINLSNNKLIGTIPKSLQRFQSSAFSGNNLTERKKQRKTPFGLSQLAFLLILSAACVLCVSGLSFIMITCFGKTRISGKLRKRDSSSPPGNWTSRDDNTEEGGKIIFFGGRNHLFDLDDLLSSSAEVLGKGAFGTTYKVTMEDMSTVVVKRLKEVVVGRREFEQQMEIIGMIRHENVAELKAYYYSKDDKLAVYSYYNHGSLFEILHGNRGRYHRVPLDWDARLRIATGAARGLAKIHEGKFIHGNIKSSNIFLDSQCYGCIGDVGLTTIMRSLPQTTCLTSGYHAPEITDTRRSTQFSDVYSFGVVLLELLTGKSPVSQAELVPTGGENMDLASWIRSVVAKEWTGEVFDMEILSQSGGFEEEMVEMLQIGLACVALKQQERPHIAQVLKLIEDIRSVDAE
InterPro domains: - IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [311-580]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [21-250]
- IPR013210: Leucine-rich repeat-containing N-terminal, plant-type (domain) [23-59]
- IPR003591: Leucine-rich repeat, typical subtype (repeat) [87-212]
- IPR001611: Leucine-rich repeat (repeat) [79-204]
- IPR017441: Protein kinase, ATP binding site (binding_site) [313-335]
- IPR000719: Protein kinase domain (domain) [307-581]
- IPR050994: Arabidopsis Inactive Receptor-like Kinases (family) [2-582]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0050793 (regulation of developmental process), GO:0051239 (regulation of multicellular organismal process), GO:2000241 (regulation of reproductive process), GO:0040008 (regulation of growth), GO:0050794 (regulation of cellular process), GO:0051128 (regulation of cellular component organization), GO:0080092 (regulation of pollen tube growth), GO:0048638 (regulation of developmental growth), GO:0001558 (regulation of cell growth), GO:0022603 (regulation of anatomical structure morphogenesis), GO:0051510 (regulation of unidimensional cell growth), GO:0022604 (regulation of cell morphogenesis), GO:0010769 (regulation of cell morphogenesis involved in differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)
Protein: Gap junction protein (A7VKB2)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Cell junction, gap junction {ECO:0000256|ARBA:ARBA00004610}. Cell membrane {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU000630}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU000630}.
Sequence: MTEWTLLKRLLDAVHQHSTMIGRLWLTIMVIFRLLIVAVATEDVYTDEQEMFVCNTLQPGCPNVCYDAFAPISQPRFWVFQIITVSTPSLCFIIYTWHNLSKQPEGEQIKEALERSCDSESCSIKSHKHINPSLEGVTNQKPSQASKTSSGVLSKYYIFHVCFRTILEVAFVVAQWLLFGFRVPAHFVCTSSPCMQSVDCYVSRPTEKTVFLIFMFCVGVFCIFLNFLELNHLAWKMIKRSVLVKDGSWNGYGAINQDSQSIASLTFRDVTSTTSLPTLDLVVDHQPDWTCAANCSTKKDNRGTQSKPKTNRKAKQRSTEVWI
InterPro domains: - IPR000500: Connexin (family) [1-317]
- IPR017990: Connexin, conserved site (conserved_site) [54-205]
- IPR019570: Connexin, cysteine-rich domain (domain) [167-233]
- IPR038359: Connexin, N-terminal domain superfamily (homologous_superfamily) [2-243]
- IPR013092: Connexin, N-terminal (domain) [3-235]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0015267 (channel activity), GO:0022829 (wide pore channel activity), GO:0005243 (gap junction channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0071840 (cellular component organization or biogenesis), GO:0007275 (multicellular organism development), GO:0016043 (cellular component organization), GO:0044085 (cellular component biogenesis), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048731 (system development), GO:0022008 (neurogenesis), GO:0030030 (cell projection organization), GO:0007399 (nervous system development), GO:0034330 (cell junction organization), GO:0030182 (neuron differentiation), GO:0048666 (neuron development), GO:0022607 (cellular component assembly), GO:0007416 (synapse assembly), GO:0048699 (generation of neurons), GO:0050808 (synapse organization), GO:0120036 (plasma membrane bounded cell projection organization), GO:0034329 (cell junction assembly)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0030054 (cell junction), GO:0070161 (anchoring junction), GO:0005886 (plasma membrane), GO:0005911 (cell-cell junction), GO:0005921 (gap junction)
Protein: C3H1-type domain-containing protein (Q57ZJ1)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Sequence: MPGCLSALASHVESASVVSTKSKRKRKSKKKALYDQYLADSGSEDSSELSKNVNGTPSKYEYEEFEPGMDINILIQQTIQNVVQSVCLEDCDGLSQFGDNDLICFSAAVKHNSSILSLQIRYLDVSDVSLVPLCRALECHPSIRALDLSGTRGGRPSVKAVFQLVCTNPNILFVRLDDTMVSPHDAEDIRVATLYNALACPDPTNNPFYLGLLRKISDIEEEKQKYKEQLSEQLWLFSSRPQNNLNSGKEKKVGFSEKVSESRIGADVCAQFMSGRCAYGSRCRYIHPDKTTALRNAIALSKYKMAQMIDDDAKSVKSSATSLGQTGRGRLQSRLRPTNFTMNKVHCAVATVHEGSVEQCSAGSNEEAADVALRLSIWTFALVTAVCSVVLIVVY
InterPro domains: - IPR000571: Zinc finger, CCCH-type (domain) [263-290]
- IPR041367: E3 ligase, CCCH-type zinc finger (domain) [268-288]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [71-196]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0019222 (regulation of metabolic process), GO:0060255 (regulation of macromolecule metabolic process), GO:0010468 (regulation of gene expression), GO:0010608 (post-transcriptional regulation of gene expression)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)