Protein: Conserved oligomeric Golgi complex subunit 8 (COG complex subunit 8) (Component of oligomeric Golgi complex 8) (Q84K25)
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. Involved in pollen tube growth by modulating Golgi morphology and vesicle trafficking homeostasis leading to the deposition of cell wall components and proteins at the pollen tube tip. Required for sporophytic development.
Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:27448097}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q96MW5}.
Sequence: MAMEVGEMSQPEATASLLSLASATQQPYVSELLSFTLDRLHKEPELLRVDAERIQRQMQEVAVGNYRAFITAADALLAIRQEVSSIDKHLESLIGEVPKLTSGCTEFIDSAENILEKRKMNQALLANHSTLLDLLEIPQLMDTCVRNGNFDEALDLEAFVSKLATLHPKLPVIQALAAEVRQTTQSLLSQLLQKLRSNIQLPECLRIIGYLRRIGVFGEYEMRLQFLRCREAWLTGILEDLDQKNAYEYLKGMINCHRMHLFDVVNQYRAIFSDDTSGSEENYDGGLLFSWAMHQITSHLKTLKIMLPKITEGGSLSNILDQCMYCAMGLGGVGLDFRGLLPPLFEEAVLNLFSKNMSTAVENFQLVLDSHRWVPLPSVGFPSSGINEDSKDDVTPPSYLMEHPPLAVFINGVSSALNELRPCAPLSLKNVVAHELIKGLQAVSDSLLRYNTTRMLRLSESNLFLSLCRAFVEVVFPHCATCFGRCYPGGATIVMDAKSAYEGLGRILAASSSQEPSNKSPKVISTDTKDASENGVASQPEEKQAENPNAKEEDNSPIPLQTPEITPES
InterPro domains: - IPR016632: Conserved oligomeric Golgi complex subunit 8, Metazoal and Viridiplantae (family) [6-568]
- IPR016159: Cullin repeat-like-containing domain superfamily (homologous_superfamily) [131-348]
- IPR007255: Conserved oligomeric Golgi complex subunit 8 (family) [2-552]
Interaction partners: - Conserved oligomeric Golgi complex subunit 2
- Conserved oligomeric Golgi complex subunit 1
- Conserved oligomeric Golgi complex subunit 6
- Conserved oligomeric Golgi complex subunit 5
- Conserved oligomeric Golgi complex subunit 3
- Conserved oligomeric Golgi complex subunit 4
- Conserved oligomeric Golgi complex subunit 7
- Vacuolar protein sorting-associated protein 54, chloroplastic
- Vacuolar protein sorting-associated protein 53 A
- Vacuolar protein sorting-associated protein 52 A
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0044237 (cellular metabolic process), GO:0008037 (cell recognition), GO:0051301 (cell division), GO:0071704 (organic substance metabolic process), GO:0003006 (developmental process involved in reproduction), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0044238 (primary metabolic process), GO:0009791 (post-embryonic development), GO:0048316 (seed development), GO:0048508 (embryonic meristem development), GO:1905393 (plant organ formation), GO:0010223 (secondary shoot formation), GO:0009888 (tissue development), GO:0048731 (system development), GO:0010016 (shoot system morphogenesis), GO:0009790 (embryo development), GO:0048608 (reproductive structure development), GO:0009793 (embryo development ending in seed dormancy), GO:0010074 (maintenance of meristem identity), GO:0048367 (shoot system development), GO:0061458 (reproductive system development), GO:0048507 (meristem development), GO:0010087 (phloem or xylem histogenesis), GO:0010346 (shoot axis formation), GO:0010154 (fruit development), GO:0010089 (xylem development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)