Protein: Anoctamin (O97132)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Membrane {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU280814}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU280814}.
Sequence: MSEDAKSPGPRTRNIIENQLFRRQRSLKLEALQRQRTLDSNDGVEGLGADTEPFDKTHIVIIFTEKAKLRHCQDVEKIIQEFGIQTTLEIVGKTEKYLYLSASVDTLLRLADAAELEKMTTTHSMQKFNHGCISDFLLPGMGKEQILRYCEIPVLIKDVIQDGIKSYVQKGYIEDMFPLHDILYLERFNWNLKRTKLPIEDIRNYFGSSIGLYFGFIEFYTKALIFPSLFGILQYVFDLNISLVCSFYVVWTTIFLELWKRKCAGYSYRWGTIEMSSLDKPRSAYTGQLKPDPITGKMTLHYPMRYTYLQMYCISYPVVLGCVVAAGWFALYQFQIEAEVLADFGPDSWLLYVPVIVQSVLIAIFSWAYEKLATFLTNLENHRTRSQYDRHRVNKLMLFEIVNNFFSQFYIAFVLHDLRQLKYQLMMQLLVFQLLCIAQEIGIPLLAVLRQKYAEFRHREVAEEKLRSISDLPRYEQSFYESGLDEYHSTYEDYLQVCIQFGFVVLFAAVAPFAAIGALLNNVFAVHIDMWKLCNIFKRPFARRAKNIGAWQLAFELLSVMSLLSNCGLLFLQPNVKDFFSHWLPSVPDLSFVIFEHLLLGLKFLIHKVIHERPRWVRIGLLKADFETSQALKQLKKFKAEANKMA
InterPro domains: - IPR007632: Anoctamin (family) [146-638]
- IPR049452: Anoctamin, transmembrane domain (domain) [202-620]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transporter activity), GO:0008509 (monoatomic anion transmembrane transporter activity), GO:0015103 (inorganic anion transmembrane transporter activity), GO:0015267 (channel activity), GO:0005216 (monoatomic ion channel activity), GO:0015108 (chloride transmembrane transporter activity), GO:0005253 (monoatomic anion channel activity), GO:0022839 (monoatomic ion gated channel activity), GO:0022836 (gated channel activity), GO:0005254 (chloride channel activity), GO:0005244 (voltage-gated monoatomic ion channel activity), GO:0061778 (intracellular chloride channel activity), GO:0022832 (voltage-gated channel activity), GO:0005247 (voltage-gated chloride channel activity), GO:0008308 (voltage-gated monoatomic anion channel activity), GO:0005229 (intracellular calcium activated chloride channel activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0055085 (transmembrane transport), GO:0033036 (macromolecule localization), GO:0070727 (cellular macromolecule localization), GO:0034220 (monoatomic ion transmembrane transport), GO:0051668 (localization within membrane), GO:0045184 (establishment of protein localization), GO:0006810 (transport), GO:0071702 (organic substance transport), GO:0008104 (protein localization), GO:0006811 (monoatomic ion transport), GO:0015698 (inorganic anion transport), GO:0072657 (protein localization to membrane), GO:0006821 (chloride transport), GO:1902476 (chloride transmembrane transport), GO:0006812 (monoatomic cation transport), GO:0006820 (monoatomic anion transport)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0016020 (membrane), GO:0005886 (plasma membrane)