Protein: Klarsicht, isoform B (LD36052p) (Q7YU15)
Organism: Drosophila melanogaster (Fruit fly)
Function: Not known
Subcellular location: Nucleus membrane {ECO:0000256|ARBA:ARBA00004126}.
Sequence: MEMQQENETGREGVIPNSEKEVALISNQETEKAAMISGGKEGSVRDLESPNETATTQKIEHTTKPLKLDGIFAMPATPPNRAGLTTKSASSSRSSSLKKQRRGSRGSANLNVAGTGDGAPKRSAPGGGQLNYGTNSVGNDLMKQSQSMTSLKASNEEQQESRDVIQAKLHLERPYNSLKKNSHSNKMHRYSWGSGNSQCSSTSLHSSATLGLGSSGKDDLWAAIQTNYNYIMDTNLLDTCKEARCEIEGAATVLEKSSECSFKMLDETQRPEGLCEDPKELRRWLREMENKLESSPTITELTLFGNAELQRHLAVHSVLYHEIASHARVVSSCIRAAEKEQQLQQQQQLSSQQPASLTSNCSSESTSESATKSSSLSSGFASDPVTTPIGTAAAAPPSSSTHPSKKGEGNLERLRDRYHLLYLKAFELQLCLDNLLRKRSSAANGLDDDEDEEEDTEDDSFGYEGEATEDDLNEVNSDLDLENSESKSATPAELILQRCQIAATQIVCGLDETQSQSRSQQVPSQAKSPSADQPRDCLAPQKILKSADASTDDDDEGWLYTATAAATLEVATAATAAPTAAAATSSVDGLQSTAVSSTTATGGPLPPSDDSDKENKVALVSATTITAAATATATSIATLHSSNYDSSSACSSSNSNSNSNSNSNGRLTETSATSRVTQLQMQIHSQSQSQSQMELQINGNAIDGRHIISNNNCYSSMQHQPQNNNEGEAAEDLAKIKMGDDEAAADMANGNATKSQQMSNGVYSRADSCNFTVWAAETVASCHLPPRSPAKSAKSSKSQASNATVSGSTLVSPVKGKVSHDSIKQLVLEAEHLVRDAQETALKTPTKQKHSIIKISSTVKKREVTMPHPIKQRVEEWLEHQPSTPQLLTRSHTHELLPSCKPDDCEASGEASETDSVPQAGAGVNGGAPNGAGSDTSEGFTDSIATCMQTSTNSYGNSTERIGGSAEPIGQPVTPLGFGSSNQSLNVKIVKRSQTRRKSERPWSVSCLSQLTTDAAQLTTARIVENSPSGLASHSISESALDSLSPGPRPRAASSSGTGSNAAKKADSKGSLRRRKARKKRISAASAGRKSDSGSELGGDLTQTLMKSCESMSSQQLQEFTNALLSIQKGAVVAPLSPKGDVSGVPSLADGEGGETQLMLPKFRVGSFTTAGLLATDTRLGALAALSNYMNEDEQQAELSTEDHHSSISETAWDNYQEKYNSENYSEGFDSDAARRLLEFGDDYRNFIDSQSDCCSSLSAANNLDSFSPPRMDSLQKHELKTLHINQDTITSTVDHARRQRALELQYERRRKTLEVRRKSCQDMDESLMASPQSDQQQQQLQVTPSLSASATALMTTPKIQSTSHQISHRAESVGRKLDFGGMSHSAQSLLRRTSESDTSTRRRRTVTADERRRSSRNLEKCIKLIPATTSSSSGSDSEDGEQEMRSLLQQSRDRLDDTRALKIRCHLLRPEDYNEIINTCRDNIRCLEAVLRGPPGTVLSNHCAGQTKDLLGAWEDLLSWSENASAARKLQQEMSVLKSSLQRLGDKPTPELLDTEPAIQIAVEALKLEQTQLTSYRTNMLRLNASVHSWLTKQERRLQSALEEQEQQQESEQLKQQKLVEEEKGADVQKELASTGAVAITVTDSNGNQVEALATGEASTSTPAWDVHTLMSSEQEFHKHLKNEVSDMYSSWDEADARINTQLEMLTNSLIAWRQLESGLSEFQLALGQDRGTLKGLEGALDKGQATPVELAQNVKLVAKLLSEKVHVSQEQLLAVQQHLDPNHIYHITKFTASNGSLSDSGISDGGATSDGGLSERERRLGVLRRLAKQLELALAPGSEAMRSIAARMESAEADLKHLQNTCRDLIVRTAASHQQKQQIQQNQTQQVSPKANGHIKKQAAKGKAEPQSPGRRGKGARKARQAKKAGEDQQVEEPSLSPEQQKMVLKQLKTLTSGDGGDDPSDDPSLLFNLESSEEDGEGADPAQTSKRGWAWRIARAAVPMQVALFTIFCAACLMQPNCCDNLNNLSMSFTPQLRYIRGPPPI
InterPro domains: - IPR012315: KASH domain (domain) [1990-2045]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0019894 (kinesin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040011 (locomotion), GO:0051179 (localization), GO:0050789 (regulation of biological process), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0048869 (cellular developmental process), GO:0051641 (cellular localization), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:2000241 (regulation of reproductive process), GO:0032879 (regulation of localization), GO:0060361 (flight), GO:0051234 (establishment of localization), GO:0071840 (cellular component organization or biogenesis), GO:0048646 (anatomical structure formation involved in morphogenesis), GO:0033036 (macromolecule localization), GO:0009791 (post-embryonic development), GO:0065008 (regulation of biological quality), GO:2000242 (negative regulation of reproductive process), GO:0050794 (regulation of cellular process), GO:0007017 (microtubule-based process), GO:0048523 (negative regulation of cellular process), GO:0051640 (organelle localization), GO:0051049 (regulation of transport), GO:0035148 (tube formation), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0060341 (regulation of cellular localization), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0051649 (establishment of localization in cell), GO:0000226 (microtubule cytoskeleton organization), GO:0007317 (regulation of pole plasm oskar mRNA localization), GO:0010876 (lipid localization), GO:0007018 (microtubule-based movement), GO:0035295 (tube development), GO:0061061 (muscle structure development), GO:0009887 (animal organ morphogenesis), GO:0046907 (intracellular transport), GO:0051656 (establishment of organelle localization), GO:0035152 (regulation of tube architecture, open tracheal system), GO:0006810 (transport), GO:0016043 (cellular component organization), GO:0002164 (larval development), GO:0051647 (nucleus localization), GO:0035239 (tube morphogenesis), GO:0035149 (lumen formation, open tracheal system), GO:0010970 (transport along microtubule), GO:0048880 (sensory system development), GO:0030705 (cytoskeleton-dependent intracellular transport), GO:0007423 (sensory organ development), GO:0090596 (sensory organ morphogenesis), GO:0071702 (organic substance transport), GO:0099111 (microtubule-based transport), GO:0072384 (organelle transport along microtubule), GO:0048666 (neuron development), GO:0006869 (lipid transport), GO:0022008 (neurogenesis), GO:1904580 (regulation of intracellular mRNA localization), GO:0034453 (microtubule anchoring), GO:0007399 (nervous system development), GO:0048569 (post-embryonic animal organ development), GO:0060541 (respiratory system development), GO:0007097 (nuclear migration), GO:0007523 (larval visceral muscle development), GO:0007517 (muscle organ development), GO:0006996 (organelle organization), GO:0030182 (neuron differentiation), GO:0061024 (membrane organization), GO:0032386 (regulation of intracellular transport), GO:0048592 (eye morphogenesis), GO:0001654 (eye development), GO:0007522 (visceral muscle development), GO:0046530 (photoreceptor cell differentiation), GO:0150063 (visual system development), GO:0007424 (open tracheal system development), GO:0042461 (photoreceptor cell development), GO:0007010 (cytoskeleton organization), GO:0006997 (nucleus organization), GO:0048699 (generation of neurons), GO:0048749 (compound eye development), GO:0001745 (compound eye morphogenesis), GO:0001754 (eye photoreceptor cell differentiation), GO:0042462 (eye photoreceptor cell development), GO:0042051 (compound eye photoreceptor development), GO:0001751 (compound eye photoreceptor cell differentiation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0016020 (membrane), GO:0048471 (perinuclear region of cytoplasm), GO:0031975 (envelope), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0099080 (supramolecular complex), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0005881 (cytoplasmic microtubule), GO:0043229 (intracellular organelle), GO:0019867 (outer membrane), GO:0043228 (non-membrane-bounded organelle), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0099081 (supramolecular polymer), GO:0005635 (nuclear envelope), GO:0043227 (membrane-bounded organelle), GO:0005640 (nuclear outer membrane), GO:0031965 (nuclear membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0031968 (organelle outer membrane), GO:0099512 (supramolecular fiber), GO:0005811 (lipid droplet), GO:0099513 (polymeric cytoskeletal fiber), GO:0005634 (nucleus), GO:0005856 (cytoskeleton), GO:0005874 (microtubule), GO:0015630 (microtubule cytoskeleton)