Protein: PEP-dependent dihydroxyacetone kinase 2, phosphoryl donor subunit DhaM (EC 2.7.1.121) (PTS system EIIA component) (Phosphotransferase enzyme IIA component) (Q92ET9)
Organism: Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)
Function: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.
Subcellular location: Cytoplasm {ECO:0000305|PubMed:22773791}.
Sequence: MISIVLVSHSQKITEGLQEMIVEMVGDTVHIISSGGTGDGRLGTNALMIADNIATCTNSEHIYIFCDIGSAILSAETALELLDTELLEKTTIIDAPLVEGAFTAAVQSLVNPSKEAILQELTNVH
InterPro domains: - IPR039643: Dihydroxyacetone kinase phosphotransferase subunit DhaM (family) [1-124]
- IPR004701: Phosphotransferase system, mannose-type IIA component (domain) [1-125]
- IPR012844: Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain (domain) [3-124]
- IPR036662: Phosphotransferase system, mannose-type IIA component superfamily (homologous_superfamily) [1-125]
Interaction partners: - PTS-dependent dihydroxyacetone kinase 2, dihydroxyacetone-binding subunit DhaK
- PEP-dependent dihydroxyacetone kinase 2, ADP-binding subunit DhaL
- PEP-dependent dihydroxyacetone kinase 1, ADP-binding subunit DhaL
- PTS-dependent dihydroxyacetone kinase 1, dihydroxyacetone-binding subunit DhaK
- NAD-dependent glycerol dehydrogenase
- PEP-dependent dihydroxyacetone kinase 1, phosphoryl donor subunit DhaM
- Glycerol-3-phosphate dehydrogenase
- Glycerol-3-phosphate dehydrogenase [NAD
- HTH-type transcriptional regulator GolR
- Triosephosphate isomerase 2
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0043412 (macromolecule modification), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0009451 (RNA modification), GO:0006400 (tRNA modification), GO:0034470 (ncRNA processing), GO:0034660 (ncRNA metabolic process), GO:0002097 (tRNA wobble base modification), GO:0006399 (tRNA metabolic process), GO:0008033 (tRNA processing), GO:0002098 (tRNA wobble uridine modification)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0071944 (cell periphery), GO:0030312 (external encapsulating structure), GO:0005618 (cell wall), GO:0009277 (fungal-type cell wall)