Protein: Probable septum site-determining protein MinC (Q55901)
Organism: Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
Function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity).
Sequence: MSDDTPHPEWQLVPQGNFVRLSLTLPTVTTAPDSPSLVFSHQQLEQSLGNYLRIMAGRWQDQTLVRLAVNNQLLDARQLQAIAAGLKEQNLTLQWVETNRRQTAVAAASAGLSVDQTMADKPLVDPSETPSLPKPLVVRHTLRSGGEIRHGGDVVIIGDVNPGSSIVADGDILIWGCLRGMAHAGAKGNDQAVIMILRLAACQIRIGDRLARVGADAVDRREPEIAYITSEGIRLTPVRQFQRSALL
InterPro domains: - IPR016098: Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal (homologous_superfamily) [134-246]
- IPR036145: Septum formation inhibitor MinC, C-terminal domain superfamily (homologous_superfamily) [135-239]
- IPR005526: Septum formation inhibitor MinC, C-terminal (domain) [137-231]
- IPR013033: Septum formation inhibitor MinC (family) [11-243]
Interaction partners: - Septum site-determining protein MinD
- Cell division protein FtsZ
- Cell division protein SepF
- Putative cell division topological specificity factor
- Penicillin-binding protein
- Sll0445 protein
- Probable peptidoglycan glycosyltransferase FtsW
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0044237 (cellular metabolic process), GO:0042221 (response to chemical), GO:0006807 (nitrogen compound metabolic process), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0048523 (negative regulation of cellular process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0060548 (negative regulation of cell death), GO:0010941 (regulation of cell death), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0070887 (cellular response to chemical stimulus), GO:0016043 (cellular component organization), GO:1901700 (response to oxygen-containing compound), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0010033 (response to organic substance), GO:0010182 (sugar mediated signaling pathway), GO:0009743 (response to carbohydrate), GO:0090304 (nucleic acid metabolic process), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:0071310 (cellular response to organic substance), GO:1901701 (cellular response to oxygen-containing compound), GO:0070542 (response to fatty acid), GO:0022607 (cellular component assembly), GO:0042981 (regulation of apoptotic process), GO:0051017 (actin filament bundle assembly), GO:0071322 (cellular response to carbohydrate stimulus), GO:0043066 (negative regulation of apoptotic process), GO:0006396 (RNA processing), GO:0034284 (response to monosaccharide), GO:0009746 (response to hexose), GO:0071326 (cellular response to monosaccharide stimulus), GO:0071331 (cellular response to hexose stimulus), GO:0009749 (response to glucose)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005737 (cytoplasm), GO:0005622 (intracellular anatomical structure)