Protein: Clathrin coat assembly protein, putative (Q385T8)
Organism: Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Function: Not known
Subcellular location: Membrane, clathrin-coated pit {ECO:0000256|ARBA:ARBA00004600}.
Sequence: MNSKDTNELKRGAGYLKEKAIIGLTRVTGNELDRAIYKVTSHKLKAPKEKHMQRVLAATRGYSSQKTHKGRNTCEYIVSEFEKRLHTHNWIVVLKTLVTFHRLMKDGSDEVNNCIQQNRNIFCFRNIKDLSESSEGAVQSVFIRQYMYYLEERSSSQRKLGASKRMENSEFGVFLRSLDVDTLGPVFESLLVQLSALVEVQYKEAIVDNFCTMEAFQRLVNDGKLLYQILSDRAIFILDGFSGFTLQQKKDWVRRYREYTVVGERLRLLFESIANSKRMFDEPPPPLKALPGSLLESLEREVRLSSIAHEDITETLESLGITADEKTPLKATTSDGTMAIYSPVATEKALDTTETGAPPVTEPKKESGFSIDDLFVPPPVTDSHQQTSYNPSTIPQGTQMEGPLIQTEANPNMTYTFPTGVPVGQNFFGQQPTGNSLTWEAPSPAPGSMQPQSAAGIVPSWSDSSASWGRGNCGSNTVDPFKDLYASQKGGQ
InterPro domains: - IPR008942: ENTH/VHS (homologous_superfamily) [6-163]
- IPR013809: ENTH domain (domain) [24-164]
- IPR011417: AP180 N-terminal homology (ANTH) domain (domain) [31-302]
- IPR048050: AP180-like N-terminal domain, plants (domain) [32-157]
- IPR014712: ANTH domain superfamily (homologous_superfamily) [182-306]
- IPR045192: Clathrin coat assembly protein AP180-like (family) [10-388]
Interaction partners: - Clathrin heavy chain
- AP-1 complex subunit gamma
- AP complex subunit sigma
- non-specific serine/threonine protein kinase
- AP complex subunit sigma
- AP complex subunit beta
- Epsin, putative
- Mu-adaptin 4, putative
- Polyubiquitin, putative
- AP-4 complex subunit epsilon
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016763 (pentosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0065009 (regulation of molecular function), GO:0044237 (cellular metabolic process), GO:0061919 (process utilizing autophagic mechanism), GO:0009056 (catabolic process), GO:0051649 (establishment of localization in cell), GO:0050790 (regulation of catalytic activity), GO:0044093 (positive regulation of molecular function), GO:0046907 (intracellular transport), GO:0044248 (cellular catabolic process), GO:0006810 (transport), GO:0006914 (autophagy), GO:0016236 (macroautophagy), GO:0016482 (cytosolic transport), GO:0016192 (vesicle-mediated transport), GO:0043085 (positive regulation of catalytic activity), GO:0051336 (regulation of hydrolase activity), GO:0043087 (regulation of GTPase activity), GO:0051345 (positive regulation of hydrolase activity), GO:0043547 (positive regulation of GTPase activity)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0020016 (ciliary pocket), GO:0071944 (cell periphery), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0005905 (clathrin-coated pit), GO:0031090 (organelle membrane), GO:0030117 (membrane coat), GO:0120025 (plasma membrane bounded cell projection), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0005768 (endosome), GO:0048475 (coated membrane), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0030135 (coated vesicle), GO:0043231 (intracellular membrane-bounded organelle), GO:0030118 (clathrin coat), GO:0098588 (bounding membrane of organelle), GO:0031982 (vesicle), GO:0012506 (vesicle membrane), GO:0030659 (cytoplasmic vesicle membrane), GO:0030136 (clathrin-coated vesicle), GO:0030662 (coated vesicle membrane), GO:0097708 (intracellular vesicle), GO:0030665 (clathrin-coated vesicle membrane)