Protein: Probable 20S rRNA accumulation protein 4 (P87156)
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Function: Required for processing of the 20S pre-rRNA at site D to generate mature 18S rRNA.
Subcellular location: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
Sequence: MSQKWVQTQAWLGFPDVPISQEDKPDEYSTFLGGFPVFFDGCSLNPNIIKCGNCKNLCRLLLQCYAPLEGDNLKERALYVWGCHNPSCRRVPNSIVCVRGVRLPLKSDIEAVKSPKAISHLEEKKSSPKEKKVNPFAITSESSRGLNPFSDATSANNPFSLSTDVNPSKPSSNVFSKPSFAAKAQQSITDQQKTQAKTKTKHIALTTSGMSVHPPVTETYTYPVTEAFQGMFLGLDLEYVPQNKVNSKKDDFSTFKNYTPYLNDSSEAWEKESYEKSPSVYEKTFRLFSEKISHNPTQCLRYERGGTPLLASGRDKLGQQLKSVTNFGKSPVPLCPLCKSPRLFEMQLMPHAISILNDEIAEWSTILVATCSMDCNPPINKDRVGYAVEWVGIQWD
InterPro domains: - IPR007320: Programmed cell death protein 2, C-terminal (domain) [283-395]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0045182 (translation regulator activity), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:0090079 (translation regulator activity, nucleic acid binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0008135 (translation factor activity, RNA binding), GO:0003743 (translation initiation factor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0071840 (cellular component organization or biogenesis), GO:0071704 (organic substance metabolic process), GO:0044238 (primary metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:1901564 (organonitrogen compound metabolic process), GO:1901576 (organic substance biosynthetic process), GO:0006139 (nucleobase-containing compound metabolic process), GO:0046483 (heterocycle metabolic process), GO:0019538 (protein metabolic process), GO:0044249 (cellular biosynthetic process), GO:0016043 (cellular component organization), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:0043603 (amide metabolic process), GO:0044260 (cellular macromolecule metabolic process), GO:0043170 (macromolecule metabolic process), GO:1901566 (organonitrogen compound biosynthetic process), GO:0006412 (translation), GO:0009059 (macromolecule biosynthetic process), GO:0006518 (peptide metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0043604 (amide biosynthetic process), GO:0044271 (cellular nitrogen compound biosynthetic process), GO:0034645 (cellular macromolecule biosynthetic process), GO:0043933 (protein-containing complex organization), GO:0006996 (organelle organization), GO:0010467 (gene expression), GO:0022607 (cellular component assembly), GO:0070925 (organelle assembly), GO:0042254 (ribosome biogenesis), GO:0042274 (ribosomal small subunit biogenesis), GO:0016070 (RNA metabolic process), GO:0043043 (peptide biosynthetic process), GO:0022618 (ribonucleoprotein complex assembly), GO:0065003 (protein-containing complex assembly), GO:0090305 (nucleic acid phosphodiester bond hydrolysis), GO:0002181 (cytoplasmic translation), GO:0071826 (ribonucleoprotein complex subunit organization), GO:0000028 (ribosomal small subunit assembly), GO:0042255 (ribosome assembly), GO:0034470 (ncRNA processing), GO:0140694 (non-membrane-bounded organelle assembly), GO:0030490 (maturation of SSU-rRNA), GO:0006364 (rRNA processing), GO:0034660 (ncRNA metabolic process), GO:0016072 (rRNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)