Protein: Uncharacterized protein (B6K4X5)
Organism: Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission yeast)
Sequence: MSGNCLTKEQLLSLTKKQALRNYQEVAYNIAIKQNTLLVMNTGAGKTLLAIKLIEYVLEQENSTCEKTSKRISIFLVPKVPLVEQQADYVQTQLNRPVGRFCGEISNLYHDNVFAEKFMKNDVVVVTGGLLFECLSKGFIKLSDVNLLIFDECHHASKDDVYVRIMKYFYHEPLREHPETIMPRVFGMTASPLMGNKWALEKEFNKLEDIYDSKLCIITDEDLGKELRSPKTFILQYSIEDFSTQSKVSDRFWKLTENFDRLKQIITRVVTETVELGLWFGDYSWQFFLRHALKKYDARRLRGAEVPKEEVLAFEALQEEVRKANLLTTSKQLRKPKLNGIDVTNKVIILYKFLRNLFATNSTARVIIFVERKVTAFLLKLFFDKIDFEGIRVESLVGNGSNQAGDEQMSYKLQKEVIRRFKHGSANVLVATAIAEEGLDIPSCDVVFRFSLCKTAIQLIQSKGRARANTSIFVNLLSEDEKELFSELCTKEIILKETLYAYCCTRSPKVEFDNNITDFFNDDNELYKIEETGALLTPFIAVSLLYGLCQRIPSDPYTLYLPEFKIQNEGEHFTCELRLPAILKIPPYITPPCRNKKKAKRYAAVKACLQLIESELIDKRLRIKTFYDELLEAEKEEQEHSMKNLPQQKWERCTPSVWQVKKHVKTVYATVIFVDSLEGESSFKCYPLLYIIPDCPFSVAGPLRLNSAKNRIDVLCHTIPTCFALDLELREELDKFTLFMLQLGLSKTLISTSSPSYWFAPLHGSYTSFESLFTIPSNAREDLRTIINVELLRKCLSENTPLHPKLLDTLSPSSLLCSAKGYYTDHHQFHSLQTSDKLGAKDEETKTFVNVIRCPLRTNFLLFQSRAVATQGAKRRKRETRVQRIEVTKLLIMPFPYEIRNSALLLPSLLYMFEQVHLVDALRVRLQAKISTKSLLEASTSPGSVLPFDYDRYEFYGDTFLKLAASNSVFLSYLWVPECKLHIERKRIIRNSTLFTISKKHDLPGFLLSEPFVIKTFIPFGYQPTQKSKNKMERSQLLANKTVADIVESSLGACLYDSGVDEALALGTRLGLNFYKTTKWDEWNSVFNVENLVPSAENDCFKHASGLESLVGYTFKHPGLLKIAFTHASYVKTTQTAVNYQQLEFLGDAVLDFIVVRYLFKKYQNKTAAELTDTKSFYVCNKSLAYVSFKLGLYDFMLQDNEDIRNAYKEYKSVIDKLQQDTKIDSNHPTPSEKFWLLIEPPKFLSDIFESFVCAVYLDSGFQFSALEPFLKFLVEELGDYEGVFNEPPVFSQINQHLQKQGCKQYKFQCVIIDEEEKSDLLYTKAVTHHYEYSLIIHDEIVCSAKALNKKNSQKLLSLALKELYQKASVRLFRKCECQLSNSD
InterPro domains: - IPR000999: Ribonuclease III domain (domain) [915-1287]
- IPR001650: Helicase, C-terminal domain-like (domain) [346-516]
- IPR014001: Helicase superfamily 1/2, ATP-binding domain (domain) [16-237]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [20-496]
- IPR036389: Ribonuclease III, endonuclease domain superfamily (homologous_superfamily) [914-1281]
- IPR038248: Dicer dimerisation domain superfamily (homologous_superfamily) [540-629]
- IPR005034: Dicer, dimerisation domain (domain) [541-631]
- IPR006935: Helicase/UvrB, N-terminal (domain) [19-192]
- IPR055044: Dicer, dsRNA-binding domain (domain) [1294-1370]
Interaction partners: - Argonaute
- RNA-dependent RNA polymerase
- Chromodomain protein Swi6
- Histone-lysine N-methyltransferase
- Double-strand siRNA ribonuclease
- Chromodomain protein Chp1
- Karyopherin
- RITS complex subunit 3
- Small ribosomal subunit protein uS9m
- Large ribosomal subunit protein bL27m
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044238 (primary metabolic process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process), GO:0006807 (nitrogen compound metabolic process), GO:0006725 (cellular aromatic compound metabolic process), GO:0034641 (cellular nitrogen compound metabolic process), GO:1901360 (organic cyclic compound metabolic process), GO:0044085 (cellular component biogenesis), GO:0006139 (nucleobase-containing compound metabolic process), GO:0043170 (macromolecule metabolic process), GO:0046483 (heterocycle metabolic process), GO:0090304 (nucleic acid metabolic process), GO:0010467 (gene expression), GO:0022613 (ribonucleoprotein complex biogenesis), GO:0042254 (ribosome biogenesis), GO:0016070 (RNA metabolic process), GO:0006396 (RNA processing), GO:0034470 (ncRNA processing), GO:0006364 (rRNA processing), GO:0034660 (ncRNA metabolic process), GO:0016072 (rRNA metabolic process)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)