Protein: Thyrotropin receptor (Q6TCF9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Function: Not known
Subcellular location: Basolateral cell membrane {ECO:0000256|ARBA:ARBA00004554}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004554}. Cell membrane {ECO:0000256|RuleBase:RU361222}; Multi-pass membrane protein {ECO:0000256|RuleBase:RU361222}.
Sequence: MVLSMMLCFILGCSMANTEDTLAASQFCAFNGSTRSFVCLGNKVLEIPRRIPTNTTFVEIKLTQISVFRRAALSELHELKRIVVSENGALERIEALAFFNLTELEEITITKSKNLVMHKDAFWRLPKLRYLTISNTGLKILPDFSKINSAALEFLFDLQDNMHIERIPSNAFLGLTNATITELRLTKNGIREIDSHAFNGTKIGKLFLMGNQQLNHIHSYAFKGAEGPVVLDISRTAVHTLPESMLKTLKLLMAVSVYSLRKLPSLELFTELTQANLTYPSHCCAFKNFKKHKSVKNQMCNVTGAHEEPDFFNFFNDHCKDVIEVTCYPTPDAFNPCEDIMGFTFLRVLIWFISVLAIVGNTVVLLVLLTSRYKLTVPRFLMCHLAFADLCMGIYLLLIAAVDIHTQSRYYNYGIDWQTGAGCHVAGFFTVFSSELSVYTLTAITLERWHTITYAMQLERQMRLRHACLVMATGWLFSLLAALMPMFGVSSYSKTSICLPMDVETLLSQGYVVLLLLLNAAAFLVVCVCYTLIYLTVRNPAFVPANADMRIAKRMAVLIFTDFLCMAPISFFAISAAFKLPLITASHAKVLLVLFYPINSCSNPFLYAFFTKTFKRDFFILTSRFGCFKRRAHIYCTEISSGQNGAVVPSPKTSDGTLYSLVHIAQVH
InterPro domains: - IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [23-345]
- IPR002274: Thyrotropin receptor (family) [73-279]
- IPR017452: GPCR, rhodopsin-like, 7TM (domain) [360-607]
- IPR000276: G protein-coupled receptor, rhodopsin-like (family) [345-615]
- IPR001611: Leucine-rich repeat (repeat) [78-138]
- IPR002131: Glycoprotein hormone receptor family (family) [334-629]
- IPR026906: BspA-type LRR region (repeat) [163-245]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0016500 (protein-hormone receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0019953 (sexual reproduction), GO:0048869 (cellular developmental process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0022412 (cellular process involved in reproduction in multicellular organism), GO:0021700 (developmental maturation), GO:0032504 (multicellular organism reproduction), GO:0003006 (developmental process involved in reproduction), GO:0048609 (multicellular organismal reproductive process), GO:0046660 (female sex differentiation), GO:0007276 (gamete generation), GO:0007281 (germ cell development), GO:0030728 (ovulation), GO:0048468 (cell development), GO:0030154 (cell differentiation), GO:0048469 (cell maturation), GO:0048731 (system development), GO:0048513 (animal organ development), GO:0048608 (reproductive structure development), GO:0009994 (oocyte differentiation), GO:0045137 (development of primary sexual characteristics), GO:0007548 (sex differentiation), GO:0001556 (oocyte maturation), GO:0007530 (sex determination), GO:0071695 (anatomical structure maturation), GO:0061458 (reproductive system development), GO:0046545 (development of primary female sexual characteristics), GO:0007292 (female gamete generation), GO:0048599 (oocyte development), GO:0048477 (oogenesis), GO:0008406 (gonad development), GO:0048232 (male gamete generation), GO:0008585 (female gonad development)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0016020 (membrane)