Protein: Cell adhesion molecule DSCAM (F1Q4W9)
Organism: Danio rerio (Zebrafish) (Brachydanio rerio)
Subcellular location: Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Synapse
Sequence: MWILAFLFLQSILNVFGEDLRSSLYFVNASLQEVVFSSTTGALVPCPAAAVPPATLRWYLATGEEIYDVPGIRHVHPNGTLQIYGFLPSSFSNLINDNTYYCTAENPSGKIRSQDLHIKAVFREPYTVRVADQRVMRGNTAVFKCIIPASVEEYVSVVSWEKDTVSLVSGSRYLITSTGALYILDVQSEDAVNIYRCTTRHRYTGETRQSNSARLLLSEPVDSAPVILDGFERKEVMVGHRVELPCKASGHPPPRYRWLRDNSPLESDSRYHQSVSGLLIEATRPSDAGSYVCEVWNSFGNAKVVGRLVVKQPLKAVVSPRKVRGSVGSQVSLFCSVTGSDEFDITWYRNAEKIYQGINVRITGINNENLVMEGMAKSDGGAYQCFARNGKMSTQDLVQVVLEDGTPKILSAFSEKVVSPNEPISLVCHVKGTPLPTVTWTLDDDPVIKDSNHRMDRIITTEGHVLSYLNVSHTQVSDGGVYRCTCNNSAGSVSYQARINVRGPASIRPMKNVTAIAGRDTYIHCRIIGYPYYSIKWYKDSNLLPFNHRQRAFENNGTLKLSNVQNSDEGEYTCYVLVDPEKQIHRSVHVTVKVPPLIQHSDSQSASIGQRVFIPCVVISGDLPMSITWHKDGRPINASLGVTIDNIDFTSSLRISNLSEIHNGSYTCIARNEAAAVEHSIQLIVKVPPHFEVQPKDQDGIYGKSVTLNCSAKGNPIPTIVWNHSKGAGVPQFQPIALNSGSRVQLLENGSLLIKHVLEEDAGFYLCKVSNDVGADISKSMYLTVKIPAMITSYPNTTRAEQGHMTEMSCTAHGEKPIKVRWEKESHIINPDMSRYVVTVKEVGDEVISTLQILHTVREDSGFFSCIAINSYGEDKGIIQLIVQDRPDPPEVEIREVKDRTIALRWTMGFDGNSPITGYDINYKNKSASWASSQMTKDVSPQLNQATIIELHPASTYNIRMFAKNQIGESRPSNELTITTDEAPPDGAPQDVQLEAISSQGIKVTWKPPHKHLQNGLIRSYQVCYREFGTGGSPQYNTINVDTTGDIETLTLDNLKKYTQYEVRVQAANRAGMGPTSEEITITTLEDVPSRPPENVVTTATTPETISLSWSALPKEALNGMLLGYRVIFWANLPDGELGEIRNITTTKPSLELERLEKYTNYSIQVLAFTRAGDGVRSEQIYTRTKEDVPGPPAGVKAAASTSSVVFVSWLPPHKLNGIIRKYIVFCSNPYPTVISEFEAAPDVYFRRLTNLNQNWQYSIWVVAVTAAGRGNTSEIITVEPQAKAPARILTFSGTVTTPWMRDIVLPCKAVGDPPPTIKWLKGNNGTPAPVSIDGRRSAHNNGSFVIRTVKAEDSGYYRCVASNNWGSDEIMLNLQVQVPPDQPRLTVTKTTTTSITLFWIPGDNGGSSIRGYILQYSEDNSEEWGSYSISPSERSYRLENLKCGTWYKFTLTAQNAVGPGRISEIIEAKTHGKEPQFAKDHELFSSINSTRVELNLIGWNNGGCPIDSFTLEYRPVDTTKWTMVKRDSLTKSHILYDLQEATWYELQMRVGNSAGTAEKRVLFATLNMDGSTIAPLPKSVDPSQENRQGNEGLKMMVTIICILVAICMVFIVLLVLRRRRREQRLKRLRDAKSLAEMLMSKNARTPDTVNKQQQTLRMHIDIPRAQLLIEERDTMETIDDRSTVLLTDNDFGETSKQKSSTVTHTVHYQSLSQATGPLVDVSDARPGTNPTARRTAKAGPATRSRYASQWTLNRPHPPVSSHTLTTDWRLPTPRATGSVDKESDSYSVSPSQDTDRARSSMVSTESASSTYEELARAYEHAKMEEQLRHAKFTITECFISDTSSEQMTAGTNDYTDSLTSSTPSESGICRFTASPPKPQDASRVMNMAVPKAHRPAGELVHLPPYLRMDFLLNRGAASSGREATGQTCMDPQKSRITKRPALLAPTPSETPSSALSSSGPPSREAVQQWQPGTASTLPQREPGDLAQAAKLSSSQESLLDSRGHLKQSNNPYAKSYTLV
InterPro domains: - IPR013098: Immunoglobulin I-set (domain) [318-883]
- IPR036179: Immunoglobulin-like domain superfamily (homologous_superfamily) [38-1385]
- IPR003598: Immunoglobulin subtype 2 (domain) [37-1367]
- IPR007110: Immunoglobulin-like domain (domain) [125-1378]
- IPR036116: Fibronectin type III superfamily (homologous_superfamily) [885-1558]
- IPR013783: Immunoglobulin-like fold (homologous_superfamily) [23-1570]
- IPR013106: Immunoglobulin V-set domain (domain) [241-1362]
- IPR003961: Fibronectin type III (domain) [886-1572]
- IPR056754: DSCAM/DSCAML, C-terminal domain (domain) [1488-1576]
- IPR003599: Immunoglobulin domain subtype (domain) [31-1378]
Interaction partners: - Netrin-1
- Netrin-1
- Down syndrome cell adhesion molecule-like 1
- Netrin receptor UNC5
- Netrin-4
- Netrin 4
- Netrin-G1
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0009653 (anatomical structure morphogenesis), GO:0048870 (cell motility), GO:0009790 (embryo development), GO:0016477 (cell migration), GO:0048598 (embryonic morphogenesis), GO:0007369 (gastrulation), GO:0001667 (ameboidal-type cell migration), GO:0042074 (cell migration involved in gastrulation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0030054 (cell junction), GO:0045202 (synapse)