Protein: Beta-synuclein (Phosphoneuroprotein 14) (PNP 14) (Q63754)
Organism: Rattus norvegicus (Rat)
Function: May be involved in neuronal plasticity.
Subcellular location: Cytoplasm {ECO:0000250}.
Sequence: MDVFMKGLSMAKEGVVAAAEKTKQGVTEAAEKTKEGVLYVGSKTKEGVVQGVASVAEKTKEQASHLGGAVFSGAGNIAAATGLVKKEEFPTDLKPEEVAQEAAEEPLIEPLMEPEGESYEDSPQEEYQEYEPEAKGP
InterPro domains: - IPR001058: Synuclein (family) [1-129]
- IPR002461: Beta-synuclein (family) [63-127]
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0008289 (lipid binding), GO:0005515 (protein binding), GO:0019904 (protein domain specific binding), GO:0019899 (enzyme binding), GO:0008092 (cytoskeletal protein binding), GO:0005543 (phospholipid binding), GO:0043274 (phospholipase binding), GO:0015631 (tubulin binding), GO:0048487 (beta-tubulin binding), GO:0008017 (microtubule binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0048519 (negative regulation of biological process), GO:0032501 (multicellular organismal process), GO:0042221 (response to chemical), GO:0019222 (regulation of metabolic process), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0007568 (aging), GO:0048523 (negative regulation of cellular process), GO:0007610 (behavior), GO:0009892 (negative regulation of metabolic process), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0060548 (negative regulation of cell death), GO:0010941 (regulation of cell death), GO:1901698 (response to nitrogen compound), GO:0010605 (negative regulation of macromolecule metabolic process), GO:1902074 (response to salt), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0070848 (response to growth factor), GO:0060255 (regulation of macromolecule metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0071495 (cellular response to endogenous stimulus), GO:1901700 (response to oxygen-containing compound), GO:0030534 (adult behavior), GO:0080090 (regulation of primary metabolic process), GO:0031324 (negative regulation of cellular metabolic process), GO:0010033 (response to organic substance), GO:1901215 (negative regulation of neuron death), GO:0042220 (response to cocaine), GO:0010243 (response to organonitrogen compound), GO:0051246 (regulation of protein metabolic process), GO:0043069 (negative regulation of programmed cell death), GO:0043067 (regulation of programmed cell death), GO:0033238 (regulation of amine metabolic process), GO:0051248 (negative regulation of protein metabolic process), GO:0042069 (regulation of catecholamine metabolic process), GO:0048148 (behavioral response to cocaine), GO:0010563 (negative regulation of phosphorus metabolic process), GO:0071774 (response to fibroblast growth factor), GO:1901214 (regulation of neuron death), GO:0014070 (response to organic cyclic compound), GO:0071363 (cellular response to growth factor stimulus), GO:0051174 (regulation of phosphorus metabolic process), GO:0042981 (regulation of apoptotic process), GO:0043279 (response to alkaloid), GO:0019220 (regulation of phosphate metabolic process), GO:0043524 (negative regulation of neuron apoptotic process), GO:0031399 (regulation of protein modification process), GO:0031400 (negative regulation of protein modification process), GO:0043066 (negative regulation of apoptotic process), GO:0044344 (cellular response to fibroblast growth factor stimulus), GO:0043523 (regulation of neuron apoptotic process), GO:0045936 (negative regulation of phosphate metabolic process), GO:0042053 (regulation of dopamine metabolic process), GO:0042325 (regulation of phosphorylation), GO:0001933 (negative regulation of protein phosphorylation), GO:0001932 (regulation of protein phosphorylation), GO:0042326 (negative regulation of phosphorylation)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0044297 (cell body), GO:0030427 (site of polarized growth), GO:0030054 (cell junction), GO:0044306 (neuron projection terminus), GO:0031975 (envelope), GO:0031974 (membrane-enclosed lumen), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0150034 (distal axon), GO:0042995 (cell projection), GO:0016020 (membrane), GO:0005829 (cytosol), GO:0098793 (presynapse), GO:0071944 (cell periphery), GO:0036477 (somatodendritic compartment), GO:0005737 (cytoplasm), GO:0012505 (endomembrane system), GO:0043679 (axon terminus), GO:0120025 (plasma membrane bounded cell projection), GO:0031410 (cytoplasmic vesicle), GO:0043229 (intracellular organelle), GO:0045202 (synapse), GO:0005794 (Golgi apparatus), GO:0030426 (growth cone), GO:0043227 (membrane-bounded organelle), GO:0005886 (plasma membrane), GO:0031090 (organelle membrane), GO:0031967 (organelle envelope), GO:0008021 (synaptic vesicle), GO:0019867 (outer membrane), GO:0030133 (transport vesicle), GO:0043228 (non-membrane-bounded organelle), GO:0042175 (nuclear outer membrane-endoplasmic reticulum membrane network), GO:0043025 (neuronal cell body), GO:0005739 (mitochondrion), GO:0043233 (organelle lumen), GO:0005783 (endoplasmic reticulum), GO:0005635 (nuclear envelope), GO:0043195 (terminal bouton), GO:0005740 (mitochondrial envelope), GO:0099503 (secretory vesicle), GO:0043232 (intracellular non-membrane-bounded organelle), GO:0070382 (exocytic vesicle), GO:0005791 (rough endoplasmic reticulum), GO:0019866 (organelle inner membrane), GO:0070013 (intracellular organelle lumen), GO:0030659 (cytoplasmic vesicle membrane), GO:0005640 (nuclear outer membrane), GO:0031965 (nuclear membrane), GO:0043231 (intracellular membrane-bounded organelle), GO:0098588 (bounding membrane of organelle), GO:0031970 (organelle envelope lumen), GO:0012506 (vesicle membrane), GO:0043005 (neuron projection), GO:0031968 (organelle outer membrane), GO:0005759 (mitochondrial matrix), GO:0031982 (vesicle), GO:0031966 (mitochondrial membrane), GO:0005741 (mitochondrial outer membrane), GO:0005758 (mitochondrial intermembrane space), GO:0005840 (ribosome), GO:0030424 (axon), GO:0005743 (mitochondrial inner membrane), GO:0097708 (intracellular vesicle), GO:0005634 (nucleus)