Protein: Abscisic acid receptor PYL3 (PYR1-like protein 10) (OsPYL10) (PYR1-like protein 3) (OsPYL3) (Regulatory components of ABA receptor 3) (Q6EN42)
Organism: Oryza sativa subsp. japonica (Rice)
Function: Involved in abscisic acid (ABA) signaling during seed germination and abiotic stress response. Acts as positive regulator of ABA-mediated inhibition of seed germination, and tolerance to drought and cold stresses. Together with PP2C50 and SAPK10, may form an ABA signaling module involved in stress response. Inhibits the protein phosphatases PP2C06 and PP2C09 when activated by abscisic acid (ABA).
Subcellular location: Cytoplasm, cytosol {ECO:0000269|PubMed:26362328}. Nucleus {ECO:0000269|PubMed:26362328}.
Sequence: MVEVGGGAAEAAAGRRWRLADERCDLRAAETEYVRRFHRHEPRDHQCSSAVAKHIKAPVHLVWSLVRRFDQPQLFKPFVSRCEMKGNIEIGSVREVNVKSGLPATRSTERLELLDDNEHILSVRFVGGDHRLKNYSSILTVHPEVIDGRPGTLVIESFVVDVPEGNTKDETCYFVEALLKCNLKSLAEVSERLVVKDQTEPLDR
InterPro domains: - IPR019587: Polyketide cyclase/dehydrase (family) [48-191]
- IPR023393: START-like domain superfamily (homologous_superfamily) [19-200]
- IPR050279: Plant defense and hormone signaling protein (family) [45-188]
Interaction partners: - Protein phosphatase 2C 50
- Probable protein phosphatase 2C 30
- Probable protein phosphatase 2C 6
- Probable protein phosphatase 2C 8
- Protein phosphatase 2C 51
- Protein phosphatase 2C 53
Gene Ontology annotations:
Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030234 (enzyme regulator activity), GO:0005515 (protein binding), GO:0140678 (molecular function inhibitor activity), GO:0004857 (enzyme inhibitor activity), GO:0019208 (phosphatase regulator activity), GO:0019888 (protein phosphatase regulator activity), GO:0019212 (phosphatase inhibitor activity), GO:0004864 (protein phosphatase inhibitor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0023052 (signaling), GO:0032501 (multicellular organismal process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0048519 (negative regulation of biological process), GO:0009628 (response to abiotic stimulus), GO:0048856 (anatomical structure development), GO:0007275 (multicellular organism development), GO:0042221 (response to chemical), GO:0009845 (seed germination), GO:0019222 (regulation of metabolic process), GO:0009791 (post-embryonic development), GO:0009892 (negative regulation of metabolic process), GO:0009719 (response to endogenous stimulus), GO:0050794 (regulation of cellular process), GO:0051716 (cellular response to stimulus), GO:0065009 (regulation of molecular function), GO:0006950 (response to stress), GO:0048523 (negative regulation of cellular process), GO:0007154 (cell communication), GO:0007165 (signal transduction), GO:0001101 (response to acid chemical), GO:0050790 (regulation of catalytic activity), GO:0009414 (response to water deprivation), GO:0051172 (negative regulation of nitrogen compound metabolic process), GO:0044092 (negative regulation of molecular function), GO:0006970 (response to osmotic stress), GO:0071495 (cellular response to endogenous stimulus), GO:0060255 (regulation of macromolecule metabolic process), GO:1901700 (response to oxygen-containing compound), GO:0031324 (negative regulation of cellular metabolic process), GO:0010033 (response to organic substance), GO:0009725 (response to hormone), GO:0090351 (seedling development), GO:0010035 (response to inorganic substance), GO:0009415 (response to water), GO:0009755 (hormone-mediated signaling pathway), GO:0070887 (cellular response to chemical stimulus), GO:0010605 (negative regulation of macromolecule metabolic process), GO:0051171 (regulation of nitrogen compound metabolic process), GO:0031323 (regulation of cellular metabolic process), GO:0080090 (regulation of primary metabolic process), GO:1902074 (response to salt), GO:0043086 (negative regulation of catalytic activity), GO:0097305 (response to alcohol), GO:0051246 (regulation of protein metabolic process), GO:0071310 (cellular response to organic substance), GO:0051336 (regulation of hydrolase activity), GO:0051248 (negative regulation of protein metabolic process), GO:0009651 (response to salt stress), GO:0009738 (abscisic acid-activated signaling pathway), GO:0032870 (cellular response to hormone stimulus), GO:0033993 (response to lipid), GO:0010563 (negative regulation of phosphorus metabolic process), GO:0009737 (response to abscisic acid), GO:1901701 (cellular response to oxygen-containing compound), GO:0051174 (regulation of phosphorus metabolic process), GO:0051346 (negative regulation of hydrolase activity), GO:0031399 (regulation of protein modification process), GO:0031400 (negative regulation of protein modification process), GO:0010921 (regulation of phosphatase activity), GO:0019220 (regulation of phosphate metabolic process), GO:0071396 (cellular response to lipid), GO:0071215 (cellular response to abscisic acid stimulus), GO:0097306 (cellular response to alcohol), GO:0045936 (negative regulation of phosphate metabolic process), GO:0010923 (negative regulation of phosphatase activity), GO:0043666 (regulation of phosphoprotein phosphatase activity), GO:0035303 (regulation of dephosphorylation), GO:0035308 (negative regulation of protein dephosphorylation), GO:0035304 (regulation of protein dephosphorylation), GO:0035305 (negative regulation of dephosphorylation), GO:0032515 (negative regulation of phosphoprotein phosphatase activity)
Cellular Component (CC): GO:0005575 (cellular component), GO:0110165 (cellular anatomical entity), GO:0005829 (cytosol), GO:0005622 (intracellular anatomical structure), GO:0043226 (organelle), GO:0005737 (cytoplasm), GO:0043229 (intracellular organelle), GO:0043227 (membrane-bounded organelle), GO:0043231 (intracellular membrane-bounded organelle), GO:0005634 (nucleus)