how long to cook oven baked tilapia fillets
1 Place tilapia, one piece at a time, into the bag with Italian dressing and shake. 2  Then put in the bag with the breadcrumb mixture and shake. 3  Repeat with other fillets. Mound any unused breading on top of fish.  Bake in 400 degree oven for 20 minutes, until fish is done and topping is browned.