what is otay
Otay Mesa is a community in the southern section of the city of San Diego, just north of the U.S.âMexico border.he Otay Mesa Port of Entry is one of two border crossings within the city of San Diego, the other being the San Ysidro Port of Entry six miles to the west. Trucks are generally instructed to use the border crossing in Otay Mesa instead of the San Ysidro one.