role of nf kb in inflammatory disease
Here, we provide a brief overview of NF-kB biology and discuss the role of NF-kB in mediating theanti-inflammatory effects of tocotrienolsThe NF-kB family of transcription factors is a central player in the regulation of inflammation and immuneresponses.ONCLUSIONS ANDFUTURE DIRECTIONS Overall, available studies are consistent with a role fortocotrienols in reducing NF-kB induction and, thereby, NF-kBâdependent induction of pro-inflammatory cytokine genes,cell cycle regulators, anti-apoptotic genes, and cell adhesionmolecules.