hippocampal sclerosis
Mesial temporal sclerosis (also known as hippocampal sclerosis) can cause a form of temporal lobe epilepsy with partial (focus) seizures that can spread or secondarily generalize and affect other areas of the brain. Treatments for temporal lobe epilepsy caused by mesial temporal sclerosis can include anticonvulsant medications and surgery.
The hippocampus is located in the medial temporal lobe, and is part of the limbic system. Damage to the hippocampus may cause problems with memory consolidation and storage. Hippocampal sclerosis is known to be associated with around three quarters of cases of temporal lobe epilepsy. An MRI scan can detect a decrease in the size of the hippocampus caused by hippocampal sclerosis.