what county is louisville
Sponsored Topics. Louisville is a city in Winston County, Mississippi, United States. The population was 7,006 at the 2000 census. It is the county seat of Winston County. Louisville is located at 33Â°7â²23â³N 89Â°3â²22â³W / 33.12306Â°N 89.05611Â°W / 33.12306; -89.05611 (33.122931, -89.056182).