best temperature to bake tilapia
1 Pour lemon juice over fillets, then drizzle butter on top. 2  Sprinkle with garlic, parsley, and pepper. 3  Bake in preheated oven until the fish is white and flakes when pulled apart with a fork, about 30 minutes. Preheat oven to 375 degrees F (190 degrees C). 2  Spray a baking dish with non-stick cooking spray. 3  Rinse tilapia fillets under cool water, and pat dry with paper towels. 4  Place fillets in baking dish. 5  Pour lemon juice over fillets, then drizzle butter on top. 6  Sprinkle with garlic, parsley, and pepper.