what is the generic name for zofran-odt
GENERIC NAME: ondansetron. BRAND NAME: Zofran, Zofran ODT, Zuplenz. DRUG CLASS AND MECHANISM: Ondansetron is an anti-nausea medication most often used to prevent nausea and vomiting caused by chemotherapy. Chemotherapy agents increase secretion of serotonin which stimulates serotonin (5-HT3) receptors in the brain, causing nausea and vomiting.