definition of osteogenesis imperfecta
Osteogenesis imperfecta (OI) is a group of genetic disorders that mainly affect the bones. The term osteogenesis imperfecta means imperfect bone formation.People with this condition have bones that break easily, often from mild trauma or with no apparent cause.ost cases of osteogenesis imperfecta have an autosomal dominant pattern of inheritance, which means one copy of the altered gene in each cell is sufficient to cause the condition. Many people with type I or type IV osteogenesis imperfecta inherit a mutation from a parent who has the disorder.