is kadcyla chemotherapy
How KadcylaTM (ado-trastuzumab emtansine) is Believed to Work (Proposed Mechanism of Action) Kadcyla is the first Genentech antibody-drug conjugate (ADC) to receive FDA approval. Kadcyla combines the mechanisms of action of trastuzumab (the antibody in Herceptin) and the chemotherapy, DM1, in one medicine. 1. Kadcyla is made up of the antibody, trastuzumab, and the chemotherapy, DM1, joined together using a stable linker. , 2. Kadcyla binds to HER2-positive cells and is thought to block out-of-control signals that make the cancer grow while also calling on the bodyâs immune system to attack the cancer cells., 3.