drugs that block serotonin receptors
5-hydroxytryptamine receptor antagonists (5-HT3 RAs) are a group of drugs which are used to control nausea and vomiting. They get their name through their ability to block 5-hydroxytryptamine (also known as serotonin) from activating nerves that bring about the vomiting reflex.5-HT 3 RAs, or serotonin blockers, were originally discovered in the 1990s and are one of the newest types of anti-vomiting drugs on the market. huge amount of research has been done on the first-generation serotonin blockers, resulting in the following key points: 1  The different serotonin blocking drugs are equally effective and can therefore be used interchangeably; 2  These drugs are well tolerated and have few side effects;