what is the mechanism of action for coumadin
Mechanism of Action of Warfarin. Warfarin is vitamin K antagonist that produce it's anticoagulant effect by interfering with the cyclic interconversion of vitamin K and its 2,3 epoxide (vitamin K epoxide). .123456 These coagulation factors (factors II, VII, IX, and X) require Ã®Â³-carboxylation for their biological activity.
BRAND NAME: Coumadin, Jantoven. Warfarin is used in treating patients with deep vein thrombosis (DVT) to prevent extension of the clot, and to reduce the risk of pulmonary embolism. Patients with pulmonary embolism are treated with warfarin to prevent further emboli.