what county is carlisle ky in
Carlisle, Kentucky. Not to be confused with Carlisle County, Kentucky. Carlisle is a home rule-class city in Nicholas County, Kentucky, United States. The population was 2,010 at the 2010 census. It is the county seat of Nicholas County. It is located at the junction of Kentucky Route 32 and Kentucky Route 36, about halfway between Lexington and Maysville.