causes of centrilobular emphysema
Three described morphological types of emphysema. Centriacinar emphysema begins in the respiratory bronchioles and spreads peripherally. Also termed centrilobular emphysema, this form is associated with long-standing cigarette smoking and predominantly involves the upper half of the lungs. Panacinar emphysema destroys the entire alveolus uniformly and is predominant in the lower half of the lungs.