dna is contained in what structure in prokaryotes and eukaryotes
â¢ DNA usually occurs as circular chromosomes in Prokaryotes while it is linear chromosomes in Eukaryotes. â¢ Eukaryote DNA has the histone protein, but prokaryote doesnât have that. â¢ Prokaryotes contain only a single loop of chromosomal DNA, whereas Eukaryote DNA is found on tightly bound and organized chromosomes.ukaryotes may be unicellular or multicellular organisms. DNA (DeoxyriboNucleic Acid) is a nucleic acid that contains the genetic information, which are used in the development and functioning of all living organisms (exception RNA viruses).