what are uncouplers
Medical Definition of UNCOUPLER. : an agent that dissociates two integrated series of chemical reactions; especially: one that prevents the formation of ATP in oxidative phosphorylation in mitochondria by dissociating the reactions of phosphorylation from those concerned with electron transport and oxidation.Dictionary: Definition of uncoupler. an agent that dissociates two integrated series of chemical reactions; especially: one that prevents the formation of ATP in oxidative phosphorylation in mitochondria by dissociating the reactions of phosphorylation from those concerned with electron transport and oxidation.