difference between steroid and protein hormones
Making the world better, one answer at a time. Steroid hormones arelipid-soluble and can dissolve easily into the cell membrane of the target cell to connect with receptors. Protein hormones are water-soluble and connect with receptors at the membrane because it can't diffuse through the membrane.nly target cells have receptors inside cytoplazm (for steroid  hormones) or on cell membrane (for protein hormones) that make the  hormone active.