How long do you cook a 2 pound meatloaf?
A 2 pound meatloaf should be cooked at 350 degrees for 1 hour or until done. The internal temperature should be abut 160 degrees.report this answer. Updated on Wednesday, February 01 2012 at 05:47PM EST. Source: allrecipes.com/... 2 pound meatloaf should be cooked at 350 degrees for 1 hour or until done. The internal temperature should be abut 160 degrees. report this answer. Updated on Wednesday, February 01 2012 at 05:47PM EST. Source: allrecipes.com/...