causes of demyelination
Causes of Demyelination. Inflammation is the most common cause of myelin damage. Other causes include: 1  inflammation. 2  infection with certain viruses. 3  metabolic problems.4  loss of oxygen.5  physical compression.S is a chronic disease where demyelination occurs in the white matter of the brain and in the spinal cord. In areas where myelin is under attack by the immune system, lesions or âplaquesâ form. These plaques are scar tissue.