what is the cost for an average sized dog to have annual vacinnations
1 The average cost for dog vaccinations ranges from $20 to $150 in the first year, and from $10 to $100 per year afterward. Most humane societies and shelters include the first rounds of vaccinations in the adoption fee. 2  Tip: It is possible to order vaccines online and vaccinate the dog yourself, but be sure you order from a reliable company.