what county is sanibel island in
Sanibel is a city in Lee County, Florida, United States, on Sanibel Island. The population was 6,469 at the 2010 census, with an estimated 2012 population of 6,741.It is part of the Cape Coral â Fort Myers Metropolitan Statistical Area.hanks to easy causeway access, Sanibel is a popular tourist destination known for its shell beaches and wildlife refuges. More than half of the island is made up of wildlife refuges, the largest being J.N. Ding Darling National Wildlife Refuge.