what cell produces pepsin
1 Pepsin is the main gastric enzyme. 2  It is produced by the stomach cells called chief cells in its inactive form pepsinogen, which is a zymogen. 3  Pepsinogen is then activated by the stomach acid into its active form, pepsin.here are four types of cells in the stomach: 1  Parietal cells: Produce hydrochloric acid and intrinsic factor. 2  Gastric chief cells: Produce pepsinogen. 3  Chief cells are mainly found in the body of stomach, which is the middle or superior anatomic portion of the stomach.