dose of amitriptyline for neuropathic pain
The typical starting dose of any TCA for the treatment of neuropathic pain is 10 to 25 mg nightly. This can be increased by 10 to 25 mg every 3 to 7 days as tolerated up to a usual maximum of 150 mg nightly.ricyclic antidepressants (TCAs) inhibit presynaptic reuptake of serotonin and norepinephrine and block cholinergic, adrenergic, histaminergic, and sodium channels. Several TCAs, including amitriptyline, nortriptyline, desipramine, and imipramine, have been studied for the treatment of neuropathic pain.