what causes a esophagus to tighten up
HealingWell.com Forum > Diseases & Conditions > GERD - Heartburn > Prokinetic agents - drugs that tighten the lower esophageal sphincter. These drugs work by tightening the lower esophageal sphincter, which helps prevent acid from washing back up into the esophagus. They also slightly increase the contractions of the esophagus and the stomach to help empty the stomach faster. Prokinetic agents include metoclopramide (also known as Reglan), bethanechol (Duvoid) and tegaserod (Zelnorm).