what is dobutamine
Dobutamine is a sympathomimetic drug used in the treatment of heart failure and cardiogenic shock.Its primary mechanism is direct stimulation of Î²1 receptors of the sympathetic nervous system. Dobutamine was developed in the 1970s by Drs.Ronald Tuttle and Jack Mills at Eli Lilly and Company, as a structural analogue of isoprenaline.obutamine is administered as a racemic mixture consisting of both (+) and (â) isomers; the (+) isomer is a potent Î² 1 agonist and Î± 1 antagonist, while the (â) isomer is an Î± 1 agonist.