what is thiopurine
Thiopurines are a class of drugs that are used to suppress the normal activity of the body's immune system. Examples of thiopurine drugs include azathioprine (ImuranÂ®), mercaptopurine (PurinetholÂ®), and thioguanine (6-TG, TabloidÂ® or LanvisÂ®).
The thiopurine drugs are purine antimetabolites widely used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis), and organ transplant recipients. Metabolism is catalyzed by S-methyltransferase.