examples of hereditary diseases in humans
Single-gene diseases run in families and can be dominant or recessive, and autosomal or sex-linked. Pedigree analyses of large families with many affected members are very useful for determining the inheritance pattern of single-gene diseases. Table 1 includes some examples of single-gene diseases.or example, identical twins with the same mutation in the gene associated with Duchenne muscular dystrophy, called DMD, can exhibit strikingly different disease phenotypes due to different patterns of X chromosome inactivation (Abbadi et al.