define von Recklinghausen's disease
Medical Definition of NEUROFIBROMATOSIS. : a disorder inherited as an autosomal dominant trait and characterized by brown spots on the skin, neurofibromas of peripheral nerves, and deformities of subcutaneous tissues and boneâabbreviation NF; called also Recklinghausen's disease, von Recklinghausen's disease.efinition of NEUROFIBROMATOSIS. : a disorder inherited as an autosomal dominant and characterized especially by brown spots on the skin, neurofibromas of peripheral nerves, and deformities of subcutaneous tissue and bone. ADVERTISEMENT. New Latin, from neurofibromat-, neurofibroma.