what is sicca syndrome
By Mayo Clinic Staff. Sjogren's (SHOW-grins) syndrome is a disorder of your immune system identified by its two most common symptoms â dry eyes and a dry mouth. Sjogren's syndrome often accompanies other immune system disorders, such as rheumatoid arthritis and lupus. In Sjogren's syndrome, the mucous membranes and moisture-secreting glands of your eyes and mouth are usually affected first â resulting in decreased production of tears and saliva.