what is dna purification
DNA isolation is a process of purification of DNA from sample using a combination of physical and chemical methods.The first isolation of DNA was done in 1869 by Friedrich Miescher. Currently it is a routine procedure in molecular biology or forensic analyses. Breaking the cells open, commonly referred to as cell disruption or cell lysis, to expose the DNA within. 2  This is commonly achieved by chemical and physical methods-blending, grinding or sonicating the sample. 3  Removing membrane lipids by adding a detergent or surfactants which also serves in cell lysis.