what is a predisposition
A genetic predisposition (sometimes also called genetic susceptibility) is an increased likelihood of developing a particular disease based on a personâs genetic makeup. A genetic predisposition results from specific genetic variations that are often inherited from a parent.lthough a personâs genetic makeup cannot be altered, some lifestyle and environmental modifications (such as having more frequent disease screenings and maintaining a healthy weight) may be able to reduce disease risk in people with a genetic predisposition.