is fexofenadine an anticholinergic
Fexofenadine is the active metabolite of terfenadine. It is a selective histamine H 1 receptor antagonist that does not cross the blood brain barrier; therefore, it is not associated with sedation or adverse cognitive effects. Unlike older antihistamines, fexofenadine does not have anticholinergic activity.here have been no comparative trials with fexofenadine and the intranasal nonsedating antihistamines (azelastine and levocabastine) in patients with seasonal allergic rhinitis. As with other oral nonsedating antihistamines, fexofenadine has little effect on nasal congestion.