what is the internal temperature of meatloaf supposed to be
Depends on how big it is. As a rule you should cook a 5lb meatloaf in a loaf pan for about 1 and a half hours at 325F. Cover with foil unless you put ketchup or catsup on top â¦ of it-you can brown it wen it's cooked. Best thing to do is to get a thermometer, once the meatloaf hits 160-165F internally then it should be moist and juicy and cooked.   See my blog for the best turkey meatloaf recipe ever and for amazing and original turkey recipes.