translocation biology definition
The final step of the elongation cycle is translocation, which brings the ribosome into the âposttranslocationalâ (POST) state, with an empty A site, peptidyl-tRNA in the P site, and deacylated tRNA in the E site. Translocation is catalyzed by the binding of EF-G and subsequent GTP hydrolysis. The movement of the tRNA molecules is concomitant with the movement of the bound mRNA chain by the length of three bases, allowing the next codon of mRNA in the ribosomal A site to be presented for decoding.