what is the action of hydrochlorothiazide
What is the mechanism of action of HCTZ? How does HCTZ work in the body? Hydrochlorothiazide (HCTZ) is a thiazide diuretic. Diuretics work by increasing the amount of fluid excreted by the kidneys. HCTZ reduces the amount of salt (sodium chloride) reabsorbed from the urine by the body in the kidneys at place call the distal convoluted tubule.