average weight loss with topamax
Results: All 5 patients had a good response to treatment at a mean topiramate dose of 195 mg/day (range, 100â375 mg/day). All patients lost a substantial amount of weight on topiramate treatment. The average weight loss was 22 lb (10 kg; range, 8â56 lb [4â25 kg]). No patient discontinued topiramate because of side effects. We started topiramate at 25 to 50 mg daily and conducted a gradual titration in increments of 25 mg. The slow titration may have been responsible for the lack of significant side effects.