what is most important chemical stimulation leading to increased rate and depth of breath
What is the medical term meaning voluntary increase in the rate and depth of breathing? What factors are most important in triggering the changes in breathing rate? Chemicals - most important are the concentrations of CO2, hydrogen  ions and O2 in the blood. Chemoreceptors are located in the  respiratory center, the carotid bodies and tâ¦he aortic bodies which  detect the levels.