what is the difference between savella and amitriptylin
In addition to relieving fibromyalgia pain, milnacipran (Savella) may help reduce the fatigue common in people who have fibromyalgia. Fibromyalgia is a chronic disorder that features:1  Widespread pain lasting at least three months. 2  Presence of other symptoms such as fatigue, waking up tired and trouble thinking.hile relief of fibromyalgia pain can help people feel less fatigued, milnacipran appears to have an additional effect on fatigue â separate from that associated with pain relief. Other treatments that may reduce fibromyalgia fatigue include better sleep hygiene, exercise and cognitive behavioral therapy.
Muscle relaxants such as Cyclobenzaprine (Flexeril) and Orphenadrine Citrate (Norflex) have also been studied in the treatment of fibromyalgia. Cyclobenzaprine has a tricyclic chemical structure similar to Amitriptyline, yet its anti-depressant effects are minimal. It is used only as a short-term muscle relaxant.ommon side effects of Amitriptyline may include morning sedation, dry mouth, confusion and urinary retention. Fibromyalgia patients seem especially sensitive to these side effects. Therefore, the dose should be individualized and generally begun at the lowest possible dose (such as 5 to 10 mg) at nighttime.