what is an example of a base substitution mutation
A frameshift mutation alters the âreading frameâ of the DNA sequence and changes all the amino acids in the protein product after the point of mutation. Substitution mutations merely replace one base with another. Because the genetic code is redundant some substitutions will have no effect at all.For example the substitution of a uracil for a cytosine in the codon CCU will have no effect on the protein produced as both CCU and CCC code for proline.Substitutions that replace one amino acid with another vary widely in their effect depending on the substitution and its location in the amino acid chain.or example the substitution of a uracil for a cytosine in the codon CCU will have no effect on the protein produced as both CCU and CCC code for proline. Substitutions that replace one amino acid with another vary widely in their effect depending on the substitution and its location in the amino acid chain.