what causes demyelination
Causes of Demyelination. Inflammation is the most common cause of myelin damage. Other causes include: 1  inflammation. 2  infection with certain viruses. 3  metabolic problems.4  loss of oxygen.5  physical compression.hen myelin is worn away or damaged, nerves donât work as well. They can deteriorate, causing problems inside the brain and throughout the body. Damage to the myelin sheath around nerves is called demyelination. Demyelination plays a part in several chronic diseases.