where does the urea cycle occur
Best Answer: ...the ammonia deposited in the mitochondria of hepatocytes (liver cells) is converted to urea in the urea cycle.. The urea cycle begins inside liver mitochondria.... - Lehninger: Principles of Biochemistry- 5th edition, 2008, p. 682. In mammals, a COMPLETE urea cycle functions only in liver, the major site of urea synthesis. - Biochemical, Physiologicalo, Molecular Aspects of Human Nutrition - 2nd edition, by Martha Stipanuk, 2006, p. 412. So, the answer is the liver because that is the ONLY organ in which the COMPLETE cycle occurs.