is gapdh a cell surface protein in humans?
1 GAPDH was identified as a binding protein on the plasma membrane of CEM-SS leukemia cells for Bt18 parasporal protein. 2  The study demonstrated that GAPDH is reliable as reference gene for quantitative gene expression analysis in human diploid fibroblasts. GAPDH is an integral part of the sarcolemmal K(ATP)-channel protein complex, where it couples glycolysis with the K(ATP)-channel activity. 2  A decrease in the dehydrogenase activity of GAPDH was noted in Alzheimer disease.