The primary immune response involves
Thus humoral immunity involves the production of antibodies by plasma cells and this constitutes the primary immune response. When there is an exposure to the same antigen second time, the memory B cells are alerted and rapidly differentiate into plasma cells that produces antibodies.This constitutes the secondary immune response.hen there is an exposure to the same antigen second time, the memory B cells are alerted and rapidly differentiate into plasma cells that produces antibodies. This constitutes the secondary immune response.