what are histamines
Histamine is secreted by basophils and mast cells as part of a local immune response to the presence of invading bodies. The basophils and mast cells are found in nearby connective tissue.This histamine release causes capillaries to become more permeable to white blood cells and other proteins, which proceed to target and attack foreign bodies in the affected tissue. Aside from humans, histamine is found in virtually all animals.y Dr Ananya Mandal, MD. Histamine is an amine that is produced as part of a local immune response to cause inflammation.
As part of an immune response to foreign pathogens, histamine is produced by basophils and by mast cells found in nearby connective tissues. Histamine increases the permeability of the capillaries to white blood cells and some proteins, to allow them to engage pathogens in the infected tissues.on-mast cell histamine is found in several tissues, including the brain, where it functions as a neurotransmitter. Another important site of histamine storage and release is the enterochromaffin-like (ECL) cell of the stomach.