difference between a gene mutation and a chromosomal mutation
Gene mutation is basically the change in the nucleotide sequence while chromosome mutation is the change in several genes. These gene mutations are basically small changes in the gene while chromosome mutation is the alteration that happens on a large scale.. Gene mutation. Gene mutation is considered as the small scale change in a nucleotide sequence. The altering of the genetic material on an organism happens in two ways. Point mutations and frame shift mutations are two bases which play a vital role whenever any change happens in a nucleotide sequence.