can glyburide cause liver damage
1 Since liver disease (including liver failure and cirrhosis) can increase your risk of lactic acidosis, you should not take glyburide and metformin if your liver is not functioning normally. 2  Also, your kidney function needs to be monitored while you are taking glyburide and metformin. If you are allergic to sulfonamides (sulfa medications), you may also be allergic to glyburide and metformin -- though most people with sulfa allergies can take glyburide and metformin without problems. 2  Let your healthcare provider know if you have a sulfa allergy.