how long for caffeine to leave the body
Advertisement. It only takes 45 minutes for 99% of the caffeine to be absorbed through these membranes. In humans the half-life for caffeine is anywhere from 4 to 6 hours on average, which explains why the average energy drink or coffeeâs effect lasts about 4 to 6 hours.n humans the half-life for caffeine is anywhere from 4 to 6 hours on average, which explains why the average energy drink or coffeeâs effect lasts about 4 to 6 hours.