what does manotil do
1 Review. Mannitol is a diuretic. Mannitol is used to force urine production in people with acute (sudden) kidney failure. Increased urine production helps to keep the kidneys from shutting down, and also speeds up elimination of certain toxic substances in the body.ou should not receive mannitol if you are allergic to it, or if you have: 1  severe or long-term kidney disease; 2  swelling or congestion in your lungs; 3  bleeding in your brain that is not related to surgery;