what does acanthosis mean
Noun. 1. acanthosis-an abnormal but benign thickening of the prickle-cell layer of the skin (as in psoriasis). disease of the skin, skin disease, skin disorder-a disease affecting the skin.oun. 1. acanthosis-an abnormal but benign thickening of the prickle-cell layer of the skin (as in psoriasis). disease of the skin, skin disease, skin disorder-a disease affecting the skin.