who plays sheldon's sister on the big bang theory
Despite Missy and Sheldon being twins they are very different both intellectually and socially. Courtney has only appeared in one episode of The Big Bang Theory - The Porkchop Indeterminacy. Missy Cooper (Courtney Henggeler): Missy is Sheldon's twin sister who is intellectually and socially very much unlike him. Confident, tall and attractive, she immediately catches the attention of Leonard, Howard, and Raj. Sheldon realizes that within Missy's eggs lies the potential for another superior mutation like him.