chronic pyelonephritis a significant cause of renal failure is most commonly caused by
Chronic pyelonephritis is characterized by renal inflammation and fibrosis induced by recurrent or persistent renal infection, vesicoureteral reflux, or other causes of urinary tract obstruction. The diagnosis of chronic pyelonephritis is made based on imaging studies such as ultrasound or CT scanning.lthough most children with chronic pyelonephritis due to VUR may experience spontaneous resolution of reflux, approximately 2% can still progress to renal failure, and 5-6% can have long-term complications, including hypertension.