types of von willebrand disease
Deficiency of VWF causes von Willebrand disease (VWD), a bleeding disorder of variable severity that is divided into several subtypes. The absence of VWF (VWD type 3) and many qualitative defects (VWD type 2) are straightforward to diagnose.on Willebrand disease (VWD) type 1 is reported to be common but frequently is difficult to diagnose. Many people have nonspecific mild bleeding symptoms, von Willebrand factor (VWF) levels display low heritability, and low VWF levels (15% to 50% of normal) are weak risk factors for bleeding.