how long for tramadol to work
Tramadol levels in the blood peak 2 hours after taking a 100 mg oral dose. In clinical studies, the onset of pain relief was faster with a combination formula of tramadol hydrochloride and acetaminophen (brand name Ultracet) than Tramadol alone. Onset of analgesia (pain relief) occurred in less than one hour. However, it takes 2 days to reach steady-state concentrations of Tramadol in the blood at a dosing rate of four times per day. As stated before Tramadol works differently for every person.