what does plague m
Wiktionary(4.20 / 5 votes)Rate this definition: 1  plague(Noun) (used absolutely, usually capitalized: The Pest) The pestilent disease Plague, caused by the virulent bacterium Yersinia pestis and mostly known by its variant form bubonic plague. 2  plague(Noun) An epidemic or pandemic caused by any pestilence, but specifically by the above disease.