what is synaptic activity
Ch.5: Synaptic Activity. Introduction. 1  Otto Loewi studied the heart of the frog, which-like our own hearts-is supplied by two different peripheral nerves. 2  One, the sympathetic nerve, excites the heart and makes it beat more rapidly; the other, the vagus, shows the heart. The influx of calcium during depolarization of the endfoot appears to activate a system of microtubules within the endfoot. 2  The microtubules exert mechanical force and induce the movement of vesicles toward the presynaptic membrane. 3  The vesicles then eject neurotransmitter into the synaptic cleft.