what is ionized calcium
Ionized Calcium (Definition). Most calcium in the blood is bound to a molecule called albumin, and this calcium fluctuates depending on the level of albumin. The rest is ionized calcium and this is freely available for biologic processes.Labs used to only be able to measure total calcium-calcium bound to Albumin + ionized.. Albumin deficiency: Total calcium is attached to albumin, an important protein in the blood. Your serum calcium may be erroneously normal if your ionized calcium is significantly elevated, look at Albumin level and also repeat the calcium tests to make sure no mistake. May need to look at mg, phos, and intact pth.