what organs or organ systems does the smallpox affect
Internal Organs. During the initial incubation period, the circulatory system carries the virus to the rest the body where it reproduces primarily within the spleen and the bone marrow as well as in other organs, including the lungs and liver.nother form of the disease, known as mailgnant smallpox, produces flat lesions, rather than the raised bumps typical of the Variola major and minor. Hemorrhagic smallpox results in significant bleeding within the skin. Both of these forms of the disease are almost always fatal.