what is cgrp
From Wikipedia, the free encyclopedia. Calcitonin gene related peptide (CGRP) is a member of the calcitonin family of peptides, which in humans exists in two forms, Î±-CGRP and Î²-CGRP. Î±-CGRP is a 37- amino acid peptide and is formed from the alternative splicing of the calcitonin/CGRP gene located on chromosome 11.onversely, CGRP is derived from dorsal root ganglion when synthesized in the dorsal horn of the spinal cord and may be linked to the transmission of pain. In the trigeminal vascular system, the cell bodies on the trigeminal ganglion are the main source of CGRP.