what is the population of spokane
(Source: U.S. Census Bureau). Spokane Countyâs population was estimated at 484,318 in 2014, making it the fourth largest county in the state. The city of Spokane recorded a population of 212,052 in 2014, 44.0 percent of the countyâs population. The populationâs total percent change from 2010 to 2014 was 2.8 percent. The increase was due to both natural increase and in-migration.