who plays catherine de medici in reign
Reign Q&A: Megan Follows (Queen Catherine!) on Playing Evil, What's Up With King Henry, and More. If you watch Reign, chances are you love Queen Catherine, perhaps the most badass mother-in-law of all time. Portrayed by Megan Follows (Anne of Green Gables), Catherine serves as equal parts adversary and mentor to Mary, who's still figuring out what it really means to be a queen. I chatted with the actress about Catherine's motivations, the murdered King Henry, Nostradamus, and growing up in a haunted house; here's what she had to say.