what is hoffman's syndrome
Hoffman Syndrome is a rare adult pseudohypertrophic myopathy associated with hypothyroidism, usually autoimmune thyroiditis. These patients present with focal or generalized muscle hypertrophy and other systemic features of hypothyroidism.There have not been many cases reported in India. We report a typical case.n our case, there was predominance of arm muscle hypertrophy alone. Hoffman's disease is a specific, rare form of hypothyroid myopathy, which causes proximal weakness and pseudohypertrophy of muscles, due to connective tissue deposition.