Familial Hypercholesterolemia definition
Definition of FAMILIAL HYPERCHOLESTEROLEMIA. : an inherited metabolic disorder marked by excess accumulation of LDL cholesterol in the blood resulting especially in atherosclerosis and irregular yellow skin lesions.ADVERTISEMENT.noun. an inherited metabolic disorder marked by excess accumulation of LDL cholesterol in the blood resulting especially in atherosclerosis and irregular yellow skin lesions. ADVERTISEMENT.