define prefrontal cortex
Prefrontal cortex. The prefrontal cortex is the anterior part of the frontal lobes of the brain, lying in front of the motor and premotor areas. This brain region has been implicated in planning complex cognitive behavior, personality expression, decision making, and moderating social behavior.iktionary (0.00 / 0 votes) Rate this definition: prefrontal cortex (Noun). The anterior part of the frontal lobes of the brain, lying in front of the motor and premotor areas.