what makes me at risk for c-diff
Risk factors for C. diff. infection include: 1  Antibiotic use, especially a type of antibiotic that is broad-spectrum (is able to treat a wide variety of bacteria) or if you have been taking antibiotics for an extended period of time. 2  Surgery of the gastrointestinal (GI) tract. 3  Abdominal surgery that requires moving the intestines aside.