how long does it take for caffien to wear off
A cup of coffee has 100-250 milligrams of caffeine. The half life of caffeine is 3 to 4 hours, depending on which version of the CYP1A2 enzyme you've inherited. In other words, if you take 250 mg, in 304 hours you'll have 125 mg left in your system.In ANOTHER 3-4 hours (6-8 from the original dose) you'll have about 60 mg in your system. Etc.ow long does it take about 250mg of caffeine to wear off, and how long does it take to kick in in the first place? if i took more but all in one go (like 400mg), would the effect take longer to wear off and how much longer?