what is the nuclear lamina
The nuclear lamina is a dense (~30 to 100 nm thick) fibrillar network inside the nucleus of most cells. It is composed of intermediate filaments and membrane associated proteins. Besides providing mechanical support, the nuclear lamina regulates important cellular events such as DNA replication and cell division.Additionally, it participates in chromatin organization and it anchors the nuclear pore complexes embedded in the nuclear envelope.he nuclear lamina is assembled by interactions of two lamin polypeptides in which the Î±-helical regions are wound around each other to form a two stranded Î±-helical coiled-coil structure, followed by a head-to-tail association of the multiple dimers.