the effects of caffeine and sleep
The effect of caffeine on sleep. It is clear that caffeine intake can affect sleep, but a large intra-individual variability in the effects of caffeine is observed. A number of factors can affect the response to caffeine consumption and the subsequent impact on sleep, as outlined below. Genetic variability
How Caffeine Prevents Sleep. Caffeine primarily prevents sleep by blocking adenosine receptors in the brain. Basically, adenosine is the neurotransmitter that signals the brain that the body is tired and in need of rest. Caffeine fits nicely into these receptors and prevents adenosine from doing its job.