what is idiotypic interaction immunology
The idiotype is based upon the variable region (labeled VL and VH in the diagram.). In immunology, an idiotype is a shared characteristic between a group of immunoglobulin or T cell receptor (TCR) molecules based upon the antigen binding specificity and therefore structure of their variable region.he variable region of antigen receptors of T cells (TCRs) and B cells (immunoglobulins) contain complementarity determining regions (CDRs) with unique amino acid sequences. They define the surface and properties of the variable region, determining the antigen specificity and therefore the idio tope of the molecule.