symptoms of als
Stages of ALS. Early Stages. Muscles. Muscles may be weak and soft or stiff, tight and spastic. Muscle cramping and twitching (fasciculations) occurs, as does loss of muscle bulk (atrophy). Symptoms may be limited to a single body region or mild symptoms may affect more than one region. The person may experience fatigue, poor balance, slurred words, a weak grip, tripping when walking or other minor symptoms.