what is a callus made of
A callus (or callosity) is a toughened area of skin which has become relatively thick and hard in response to repeated friction, pressure, or other irritation.Rubbing that is too frequent or forceful will cause blisters rather than allow calluses to form.oo much friction occurring too fast for the skin to develop a protective callus will cause a blister or abrasion instead. Biologically, calluses are formed by the accumulation of terminally undifferentiated keratinocytes in the outermost layer of skin.