is spironolactone potassium sparing
(At the same time, it also causes the kidneys to eliminate potassium.) The body then becomes overloaded with salt and water, and this worsens the heart failure. Spironolactone inhibits the action of aldosterone thereby causing the kidneys to excrete salt and fluid in the urine while retaining potassium. Therefore, spironolactone is classified as a potassium-sparing diuretic, a drug that promotes the output of urine (diuretic) while allowing the kidneys to retain potassium. The FDA approved spironolactone in October 1985.