what are h2 receptors
H2 receptors are positively coupled to adenylate cyclase via Gs. It is a potent stimulant of cAMP production, which leads to activation of Protein Kinase A. PKA functions to phosphorylate certain proteins, affecting their activity.The drug betazole is an example of a Histamine H 2 receptor agonist.he histamine receptor H 2 belongs to the rhodopsin-like family of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation.