is homologue noun
Wiktionary (0.00 / 0 votes) Rate this definition: homologue (Noun). Something homologous; a homologous organ or part, chemical compound or a chromosome. homologue (Noun). A word shared by two languages or dialects. homologue (Noun). One of a group of similar DNA sequences that share a common ancestry.hat which is homologous to something else; as, the corresponding sides, etc., of similar polygons are the homologues of each other; the members or terms of an homologous series in chemistry are the homologues of each other; one of the bones in the hand of man is the homologue of that in the paddle of a whale.