what is hydroxypropyl methylcellulose made from
HYDROXYPROPYL METHYLCELLULOSE HPMC VS MC. Hydroxypropyl Methylcellulose is non-ionic cellulose mixed ether made from refined cotton by alkaline treatment and then by a series of reactions with propylene epoxide and methyl chloride as etherifying agents. The degree of substitution is generally 1.2-2.0.. Hydroxypropyl Methylcellulose is easily soluble in cold water but difficult to be soluble in hot water. However, its gelling temperature in hot water is significantly higher than that of Methyl Cellulose (MC). And compared with MC, the dissolution in cold water has also been greatly improved. 2.