which baby graced the the first issue on tv guide cover
Vote for this answer. Lucy was on the first cover in a small picture in the top right hand corner. The. main picture is Desi Arnaz Jr., Lucy's real life son, who played Little Ricky, Lucy's TV son. You can see a picture of it here: http://pdxretro.com/2011/04/first-issue-of-tv-guide-on-this-date-in-1953/.