where is lyon located in france
History. The third largest city in France, Lyon is situated in the Rhone-Alpes region between Paris and Marseille. A UNESCO World Heritage site, the city is home to roughly 490,000 inhabitants and was prized in ancient times as a major centre for the production and sale of silk.istory. The third largest city in France, Lyon is situated in the Rhone-Alpes region between Paris and Marseille. A UNESCO World Heritage site, the city is home to roughly 490,000 inhabitants and was prized in ancient times as a major centre for the production and sale of silk.