what is lidocaine soluble in
Lidocaine is a white to slightly yellow crystalline powder. Lidocaine hydrochloride is a white odorless crystalline powder. Solubility. Lidocaine is practically insoluble in water; it is very soluble in alcohol, chloroform, and methylene chloride.It is freely soluble in ether. Lidocaine hydrochloride is very soluble in water and alcohol and soluble in chloroform, but it is insoluble in ether.ther samples of lidocaine with epinephrine were subjected to various conditions of stress such as autoclaving for 5, 10, and 20 cycles, storage for 1 month at 80 and 110 Â°C, exposure to atmospheric oxygen, addition of 12 ppm of aluminum, and an increase in the pH of the solution.