what is bu[prenorphrine
Buprenorphine/naloxone. Buprenorphine/naloxone (trade name Suboxone) is a combination drug formulation of buprenorphine, a Î¼-opioid receptor (MOR) weak partial agonist and Îº-opioid receptor antagonist, and naloxone, a MOR silent antagonist, in a 4:1 ratio. It is used in the treatment of opioid dependence.