which type of mutation affects more genes a gene mutation or a chromosomal mutation
Report Abuse. Chromosomal mutations include deletions or amplifications of large areas of a chromosome as well as inversions and translocations. Since chromosomes have many genes, a mutation to a chromosome could affect more genes than would a mutation to a single gene.bradlepe Â· 6 years ago. Thumbs up.ating Newest Oldest. Best Answer: Chromosomal mutations affect large regions of the chromosome, which may contain hundreds or thousands of genes. A gene mutation affects one gene. Thus, a chromosomal mutation will affect more genes.