what are the common diseases of endoplasmic reticulum causes (multiple choice)
It has become increasingly clear that endoplasmic reticulum stress is an important feature of a number of human diseases, particularly those involving cells dedicated to the synthesis of secreted proteins, such as diabetes mellitus, liver diseases and inflammatory disorders.evertheless, this accumulation does not lead to increased expression of the endoplasmic reticulum stress markers binding immunoglobulin protein (BIP) or CHOP. These data suggest that the role of the UPR in the pathogenesis of Charcot-Marie-Tooth 1A mutations needs to be examined directly and in greater detail.