What is the structural difference between DNA and RNA?
1 DNA contains the sugar deoxyribose, while RNA contains the sugar ribose. 2  The only difference between ribose and deoxyribose is that ribose has one more-OH group than deoxyribose, which has-H attached to the second (2') carbon in the ring.
1 The only difference between ribose and deoxyribose is that ribose has one more-OH group than deoxyribose, which has-H attached to the second (2') carbon in the ring. 2  DNA is a double stranded molecule while RNA is a single stranded molecule. 3  DNA is stable under alkaline conditions while RNA is not stable.