what is the condition caused by a genetic mutation of the gene that controls the production of hemoglobin?
Sickle cell anemia, a common form of sickle cell disease, is caused by a particular mutation in the HBB gene. This mutation results in the production of an abnormal version of beta-globin called hemoglobin S or HbS.In this condition, hemoglobin S replaces both beta-globin subunits in hemoglobin.ore than 10 mutations in the HBB gene have been found to cause methemoglobinemia, beta-globin type, which is a condition that alters the hemoglobin within red blood cells.