how can I distinguish fact from fiction
â¢ The major difference between fact and fiction is that fact is a true incident whereas fiction is an imaginative creation. â¢ Fact has nothing to do with the mind. It is an already existent event or phenomenon. On the other hand, fiction has got everything to do with the mind.â¢ The words fact and fiction show difference in terms of their origin too. Word fact is derived from the Latin factum. On the other hand, the word fiction is derived from the Latin fictio. â¢ Fiction is based on imagination and fact is based on truth.Related posts: 1  Difference Between Lane and Avenue.2  Difference Between Road and Street.ord fact is derived from the Latin factum. On the other hand, the word fiction is derived from the Latin fictio. â¢ Fiction is based on imagination and fact is based on truth. Related posts: 1  Difference Between Lane and Avenue. 2  Difference Between Road and Street.