what type of inhibitor is atp to phosphofructokinase
Phosphofructokinase (PFK) is a glycolytic enzyme that catalyzes the irreversible transfer of a phosphate from ATP to fructose-6-phosphate: fructose-6-phosphate + ATP fructose-1,6-bisphosphate + ADP.In part because of the irreversible nature of this step in glycolysis, PFK is the key regulatory enzyme for glycolysis.When ATP levels are high in the cell, the cell no longer needs metabolic energy production to occur.In this case, PFK's activity is inhibited by allosteric regulation by ATP itself, closing the valve on the flow of carbohydrates through glycolysis.Recall that allosteric regulators bind to a different site on the enzyme than the active (catalytic) site.hen ATP levels are high in the cell, the cell no longer needs metabolic energy production to occur. In this case, PFK's activity is inhibited by allosteric regulation by ATP itself, closing the valve on the flow of carbohydrates through glycolysis.