what is hydroxyeicosatetraenoic acid
From Wikipedia, the free encyclopedia. 12-Hydroxyeicosatetraenoic acid (12-HETE) is a derivative of the 20 carbon polyunsaturated fatty acid, arachidonic acid, containing a Hydroxyl residue at carbon 12 and a 5 Z, 8Z ,10 E ,14 Z Cisâtrans isomerism configuration (Z=cis, E=trans) in its four double bonds.n humans, Arachidonate 12-lipoxygenase (12-LO, 12-LOX, ALO12, or platelet type 12-lipoxygenase) is encoded by the ALOX12 gene and expressed primarily in platelets and skin.