what is agnh
An-Gong-Niu-Huang Wan (AGNH) is a famous traditional Chinese medicine used for brain trauma, hemorrhage, and coma. AGNH contains 10% realgar (As4S4) and 10% cinnabar (HgS). Both As and Hg are well-known for their toxic effects, and the safety of AGNH is of concern. To address this question, the acute toxicity of AGNH, realgar and cinnabar were compared to sodium arsenite (NaAsO2) and mercuric chloride (HgCl2). Mice were administrated orally AGNH at 1, 3 and 6 g/kg.