what does fascin
Fascin is an actin-bundling protein that is expressed by dendritic cells of the lymphoid tissue. mas. in patients treated with cyclophosphamide, doxorubicin, vincristine, and prednisolone plus rituximab (R-CHOP). patients included in the study showed fascin expression, 16 of them being diffuse and strong. whether or not having bulky disease, extranodal involvement, and international prognostic index (IPI) score. show prognostic significance of fascin expression in DLBCL patients treated with R-CHOP. However, because of the alterations in fascin expression in a variety of benign and malignant lymphoid entities, regardless of its prognostic impact, studies on fascin exp-ression may help us to understand tumor biology of lymphomas better.