biggest south carolina cities
Largest cities in South Carolina. 1  Columbia. 2  Charleston. 3  North Charleston.  Mount 1  Pleasant. Rock Hill. 2  Greenville. Summerville. 3  Sumter. Goose  Creek. Hilton 1  Head Island. 2  Florence. Spartanburg.  Aiken. 1  Myrtle Beach.  Anderson. Greer.