what's the difference between prilosec and nexium
Nexium is Esomeprazole and Prilosec is omeprazole. They are both proton pump inhibitors and chemically similar but different too. many people feel the Nexium (esomeprazole) works a little better. It is a newer generation drug than omeprazole.
For many people, Prilosec is more affordable than Nexium. Nexium is not available in a generic (as is Prilosec). Also, Prilosec is available as an over-the-counter product (Prilosec OTCÂ®), while Nexium is not. Suggestions for Choosing Between Prilosec vs. Nexium. Although the PPIs are all very similar, some people may find that one works better than the others. For most people, cost and insurance coverage are the most important factors when choosing between Prilosec and Nexium.
Omeprazole vs Esomeprazole: Where the difference lies. 1  Omeprazole is a pro-drug which is converted in the parietal cells of the stomach to the active drug in contrast to the Esomeprazole which is the active drug. 2  Omeprazole is an impure racemic mixture with R- and S- isomers.