xyrem cost
1 It may be expensive. 2  A typical fill can cost $3,406 or more for 1 bottle (180ml) 500mg/ml of Xyrem oral solution. 3  Patients in need of this drug may find most of the cost paid by an insurance company, government, or non profit organization.pecialty medication. This drug is considered a specialty medication, which means: 1  It may be expensive. 2  A typical fill can cost $3,406 or more for 1 bottle (180ml) 500mg/ml of Xyrem oral solution.