what is the gulop gene
Entrez Gene Summary for GULOP Gene. This gene is nonfunctional in humans and other primates. In most mammalian species the corresponding gene encodes L-gulono-gamma-lactone oxidase which catalyzes the last step of ascorbic acid biosynthesis.The human gene is a remnant that lacks five of twelve exons found in functional rodent genes.The loss of enzyme activity results in hypoascorbemia or the inability to synthesize vitamin C. [provided by RefSeq, Nov 2010]. GULOP (Gulonolactone (L-) Oxidase, Pseudogene) is a Pseudogene.he human gene is a remnant that lacks five of twelve exons found in functional rodent genes. The loss of enzyme activity results in hypoascorbemia or the inability to synthesize vitamin C. [provided by RefSeq, Nov 2010]. GULOP (Gulonolactone (L-) Oxidase, Pseudogene) is a Pseudogene.