what is ttp
From Wikipedia, the free encyclopedia. Thrombotic thrombocytopenic purpura (TTP or Moschcowitz syndrome) is a rare disorder of the blood-coagulation system, causing extensive microscopic clots to form in the small blood vessels throughout the body.These small blood clots, called thrombi, can damage many organs including the kidneys, heart and brain. rarer form of TTP, called UpshawâSchulman syndrome, is genetically inherited as a dysfunction of ADAMTS13. If large vWF multimers persist, a tendency for increased coagulation exists.