what could be causing a stabbing pain on a leg
1 Arthritis affecting leg joints can cause stabbing leg pain which is chronic in nature. 2  It is accompanied by inflammation and stiffness of the joint. 3  Baker's Cyst. 4  In this condition, the knee joint fluid gets accumulated at the back of the knee and pain can be felt at the back side of the leg.
The interesting location of the sciatic nerve is why it is responsible for some of the most excruciating and debilitating pain. Even in non serious cases, the big nerve can cause stabbing pain in the lower back, hips, legs and even feet and ankles.