what is a hypervariable region
A hypervariable region (HVR) is a location within nuclear DNA or the D-loop of mitochondrial DNA in which base pairs of nucleotides repeat (in the case of nuclear DNA) or have substitutions (in the case of mitochondrial DNA).Changes or repeats in the hypervariable region are highly polymorphic.VR1 is considered a low resolution region and HVR2 is considered a high resolution region. Getting HVR1 and HVR2 DNA tests can help determine one's haplogroup. HVR1 locations are numbered 16001-16568.