what precautions should be taken when collecting blood for assays of enzymatic activity
The information about collection date of the sample is critical and should be included. A precaution should be taken for the measurement of enzyme activity, related to the blood concentration in filter paper, which is not always constant. This concentration depends mainly on the sample's collection procedures [13] .ackground. Mucopolysaccharidosis IVA (MPS IVA), or Morquio Syndrome type A, is an autosomal recessive disease caused by deficiency of the lysosomal enzyme N-acetylgalactosamine-6-sulfatase (GALNS), resulting in excessive lysosomal storage of keratan sulfate in many tissues and organs.