von willebrand disease hereditary
Von Willebrand disease (vWD) (/ËfÊnËvÉªlÉ¨brÉËnt/) is the most common hereditary coagulation abnormality described in humans, although it can also be acquired as a result of other medical conditions.he von Willebrand factor is qualitatively normal and genetic testing of the von Willebrand gene and vWF protein reveals no mutational alteration. The defect lies in the qualitatively altered glycoprotein Ib (GPIb) receptor on the platelet membrane which increases its affinity to bind to the von Willebrand factor.