when did hepatitis a vaccine become mandatory
HEPATITIS B VACCINATION. The first hepatitis B vaccine became commercially available in the United States in 1982. In. 1986, a hepatitis B vaccine produced by recombinant DNA technology was licensed and a. second recombinant-type hepatitis B vaccine was licensed in 1989. The two recombinant DNA. vaccines (Recombivax HB and Engerix-B) are the only hepatitis B vaccine preparations.