what is mgp
Matrix gla protein (MGP) is member of a family of vitamin-K dependant, Gla-containing proteins. MGP has a high affinity binding to calcium ions, similar to other Gla-containing proteins.The protein acts as an inhibitor of vascular mineralization and plays a role in bone organization.MGP is found in number body tissues in mammals, birds, and fish.Its mRNA is present in bone, cartilage, heart, and kidney.It is present in bone together with the related vitamin K-dependent protein osteocalcin.he protein acts as an inhibitor of vascular mineralization and plays a role in bone organization. MGP is found in number body tissues in mammals, birds, and fish. Its mRNA is present in bone, cartilage, heart, and kidney. It is present in bone together with the related vitamin K-dependent protein osteocalcin.