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This article is about the city. For the unincorporated community in Champaign County, see Middletown, Champaign County, Ohio. For the community in Crawford County, see Middletown, Crawford County, Ohio. Middletown is a city located in Butler and Warren counties in the southwestern part of the U.S. state of Ohio. Formerly in Lemon, Turtlecreek, and Franklin townships, Middletown was incorporated by the Ohio General Assembly on February 11, 1833, and became a city in 1886.