katherine who played izzy stevens on grey's anatomy
It's Time for Katherine Heigl to Return to Grey's Anatomy, and Here's Why. Having killed off Patrick Dempseyâs Derek, Greyâs Anatomy will be headed into its 12th season this fall with less than half of its original ensemble scrubbing in. But it doesnât have to be that way, not if Katherine Heigl returns as Izzie. And, if you ask me, it could â and definitely should â happen.