what are monogenetic disorders? provide several examples
Several monogenetic disorders of the lipid metabolism are associated with low high density lipoprotein cholesterol (HDL-C) levels. In this review, familial hypo-alphalipoproteinemia, Tangier disease and lecithin cholesterol acyltransferase (LCAT) deficiency will be discussed .
Recessive diseases are monogenic disorders that occur due to damages in both copies or allele. Dominant diseases are monogenic disorders that involve damage to only one gene copy. X linked diseases are monogenic disorders that are linked to defective genes on the X chromosome which is the sex chromosome.