genetic diseases that affect bone growth
Osteogenesis imperfecta (OI) is a group of genetic disorders that mainly affect the bones.The term osteogenesis imperfecta means imperfect bone formation. People with this condition have bones that break easily, often from mild trauma or with no apparent cause.hese defects weaken connective tissues, leading to severe bone abnormalities and problems with growth. In cases of osteogenesis imperfecta without identified mutations in one of the genes described above, the cause of the disorder is unknown. These cases include osteogenesis imperfecta types V and VI.