why are allosteric molecules used in glycolysis
Allosteric regulation is organized so that molecules (like ATP and citrate), which are consistent with a high energy state of the cell, turn off glycolysis. Acetyl-CoA is consistent with a high energy state, and it turns off glycolysis and turns on gluconeogenesis as well.llosteric Regulators of Glycolysis/Gluconeogenesis control enzymes. Citrate-produced by citric acid cycle-indicator of high energy-inhibits PFK and PFK-2 (turns off glycolysis). ATP-produced in glycolysis-indicator of high energy-inhibits PFK (turns off glycolysis).