what is orkambi used for
ORKAMBI is for the chronic treatment of cystic fibrosis (CF). It is used for patients aged 12 and. older who have two copies of the F508del mutation in the cystic fibrosis transmembrane. conductance regulator (CFTR) gene (F508del/F508del). ORKAMBI should not be used in patients other than those who have two copies of the F508del. mutation in their CFTR gene. It is not known if ORKAMBI is safe and effective in children under 12 years of age.