can prilosec cause diarrhea or cramps?
Talk with your doctor. PRILOSEC can cause serious side effects, including: 1  Diarrhea. 2  PRILOSEC may increase your risk of getting severe diarrhea. 3  This diarrhea may be caused by an infection (Clostridium difficile) in your intestines. 4  Call your doctor right away if you have watery stool, stomach pain, and fever that does not go away.