where are eosinophils formed
Eosinophil maturation in bone marrow. After allergen-induced late-phase reaction, CD34+ cells express IL- 5 receptor Î±-chain. IL- 5 drives the CD34+ and IL- 5 receptor Î±-chain+ cells to eosinophil maturation. Under the stimulus of IL-5 or eotaxin, these mature cells shed L-selectin and migrate from the bone marrow to the blood.