is erythema nodosum systemic
It is a form of inflammatory disorder which is typified by the presence of tender and painful reddish lumps underneath the skin. Erythema Nodosum could be triggered by drug reactions, systemic diseases or infections. However, most cases of EN occur spontaneously. People suffering from this form of skin disorder notice 1 to 5 cm tender lumps underneath the skin, especially on the lower legs. Sponsored link.