how long to cook 3 pound meatloaf
Rating Newest Oldest. Best Answer: The thicker the meatloaf the longer it will take to reach an internal temperature of 165*F. I made a meatloaf tonight using 1 1/2 pounds of ground beef.It took one hour and ten minutes for it to reach an internal temperature of 165* F. For your 3 pound meatloaf, I'd recommend at least 1 and one-half hours at 350*F.ating Newest Oldest. Best Answer: The thicker the meatloaf the longer it will take to reach an internal temperature of 165*F. I made a meatloaf tonight using 1 1/2 pounds of ground beef.