where does a mutation have to occur in order for it to be inherited by the offspring
Mutations (2 of 2). The only mutations that matter to large-scale evolution are those that can be passed on to offspring. These occur in reproductive cells like eggs and sperm and are called germ line mutations. A single germ line mutation can have a range of effects:he only mutations that matter to large-scale evolution are those that can be passed on to offspring. These occur in reproductive cells like eggs and sperm and are called germ line mutations.