which drugs predispose the patient to peptic ulcer disease and gi bleeding?
Up to 60% of patients with a history of an upper GI bleed are bleeding from the same lesion. Ask the patient about medications. Non-steroidal anti-inflammatory drugs and acetylsalicylic acid can predispose the patient to peptic ulcer disease; antiplatelets and anticoagulants can promote bleeding; and bismuth and iron can cause stool to appear black. Liver cirrhosis can indicate varices. Aortic stenosis and renal disease can indicate angioectasia. Tobacco abuse, alcohol abuse, and Helicobacter pylori can indicate a malignancy. Marginal anastomotic ulcers can indicate gastroenteric ...