which pill is best for a migraine headache, advil or tylenol?
Confidence votes 3.7K. Advil (ibuprofen) or Aleve (Naproxen sodium, which in higher doses is a prescription non-steroidal anti-inflammatory), and aspirin may be better at helping calm down the inflammation which part of the migraine reaction than Tylenol (acetaminophen, in the UK/AU - paracetamol)