what are causes of genetic disorders
Chromosomes, distinct structures made up of DNA and protein, are located in the nucleus of each cell. Because chromosomes are the carriers of the genetic material, abnormalities in chromosome number or structure can result in disease. Abnormalities in chromosomes typically occur due to a problem with cell division. For example, Down syndrome (sometimes referred to as Down's syndrome) or trisomy 21 is a common disorder that occurs when a person has three copies of chromosome 21.