Question: who played lead guitar on who's that lady
Answer: Brother Ernie Isley 's Jimi Hendrix / Santana - inspired guitar solo was one of the elements that defined the 3 + 3 era of the Isleys , and the song became their first Top 10 pop single since 1969 's `` It 's Your Thing '' peaked at number two on the pop singles chart , reaching number six on the pop chart and number two on the US R&B Singles chart .