Developing a Silk Fibroin Composite Film to Scavenge and Probe H2O2 Associated with UVExcitable Blue Fluorescence A silk fibroin composite film that can simultaneously scavenge and probe H2O2 in situ was developed for possibly examining local concentrations of H2O2 for biomedical applications. A multifunctional composite film (GDES) that consists of graphene oxide (G), a photothermally responsive element that was blended with polydopamine (PDA, D)horseradish peroxidase (HRP, E) (or DE complex), and then GDE microaggregates were coated with silk fibroin (SF, S), a tyrosinecontaining protein. At 37 xc2xb0C, the H2O2scavenging ability of a GDES film in solution at approximately 7.5 xc3x97 10xe2x88x923 xcexbcmol H2O2mg film was the highest compared with those of S and GS films. The intensities of UVexcitable blue fluorescence of a GDES film linearly increased with increasing H2O2 concentrations from 4.0 xcexbcM to 80 xcexbcM at 37 xc2xb0C. Interestingly, after a GDES film scavenged H2O2, the UVexcitable blue fluorescent film could be qualitatively monitored by eye, making the film an eyeprobe H2O2 sensor. A GDES film enabled to heat H2O2containing samples to 37 xc2xb0C or higher by the absorption of nearIR irradiation at 808 nm. The good biocompatibility of a GDES film was examined according to the requirements of ISO109935. Accordingly, a GDES film was developed herein to scavenge and eyeprobe H2O2 in situ and so it has potential for biomedical applications.

Biomimetic Stretchable Sensor Resembling SharPei Crumples with 2D Materials towards Collaborative Robotic Minimally Invasive Procedures For the purpose of collision avoidance, medical robots can utilize tactile sensors with 2D materials including reduced graphene oxide rGO and MXene electrodes that are stretchable like the skin of humans. When the electrode surface is visualized using scanning electrode microscope (SEM), the surface morphologies have wrinkles like those found on Shar Pei dog faces. This study aims to examine the biomimetic similarity between the 2D crumples in SEM images of the electrode surface and in the images of SharPei dog faces. The similarity in 2D crumples was assessed by computing the angles made by the crumples and analyzing its distribution. This study demonstrates that there is a biomimetic similarity between the dog face and the SEM images of the rGO and MXene electrodes. This implies similar stretchable functionalities and protective principles out of the crumple geometry of the sensors and SharPei skins.