CTBased NonDestructive Quantification of 3DPrinted Hydrogel Implants Additive manufacturing of hydrogelbased implants, as e.g for the human skull are becoming more important as they should allow a modelling of the different natural layers of the skullcap, and support the bone healing process. Nevertheless, the quality, structure and consistency of such 3Dprinted hydrogel implants are important for the reliable production, quality assurance and further tests of the implant production. One possibility for nondestructive imaging and quantification of such additive manufactured hydrogels is computed tomography combined with quantitative image analysis. Hence, the goal of this work is the quantitative analysis of the hydrogelair relationship as well as the automated computation of the hydrogel angles between the different hydrogel layers. This is done by application and evaluation of various classical image analysis methods such as thresholdig, morphological operators, region growing and Fourier transformation of the CTslices. Results show, that the examined quantities (channels in the hydrogel lattice, angles between the layers) are in the expected ranges, and it can be concluded that the additive manufacturing process may yield usable hydrogel meshes for reconstructive medicine.

HighBiofidelity Biomodel Generated from ThreeDimensional Imaging (ConeBeam Computed Tomography): A Methodological Proposal Experimental research on living beings faces several obstacles, which are more than ethical and moral issues. One of the proposed solutions to these situations is the computational modelling of anatomical structures. The present study shows a methodology for obtaining highbiofidelity biomodels, where a novel imagenological technique is used, which applies several CAMCAD computer programs that allow a better precision for obtaining a biomodel, with highly accurate morphological specifications of the molar and tissues that shape the biomodel. The biomodel developed is the first lower molar subjected to a basic chewing simulation through the application of the finite element method, resulting in a viable model, able to be subjected to various simulations to analyse molar biomechanical characteristics, as well as pathological conditions to evaluate restorative materials and develop treatment plans. When research is focused in medical and dental investigation aspects, numerical analyses could allow the implementation of several tools commonly used by mechanical engineers to provide new answers to old problems in these areas. With this methodology, it is possible to perform highfidelity models no matter the size of the anatomical structure, nor the complexity of its structure and internal tissues. So, it can be used in any area of medicine.