Medication Rules of Traditional Chinese Medicine in Consolidation Period of Breast Cancer Based on Association Rules Mining Objective: To explore the association rules between medicines, core combinations and new prescriptions, and to analyze the medication rules of traditional Chinese medicine(TCM) in consolidation period of breast cancer based on data mining of medical records of TCM treatment in consolidation period of breast cancer in outpatient clinic of Hunan University of TCM in recent 10 years. Method: Use Python 3.7 software to select association rule algorithm with the minimum support degree greater than 60% and the minimum confidence greater than 0.9 to conduct data mining of the collected medical records. Results: A total of 9739 medical records and 178 Chinese herbal medicines were selected for data mining. The TCMs with higher frequency are atractylodes macrocephala, astragalus membranaceus, poria cocos, codonopsis pilosula, coix seed, hedyotis diffusa and scutellaria barbata. The top five bilinked medicines in confidence are scutellaria barbata with atractylodes macrocephala, hedyotis diffusa with atractylodes macrocephala, liquorsaturated ligustrum lucidum with atractylodes macrocephala, coii with atractylodes macrocephala, and poria cocos with atractylodes macrocephala. The top five triplelinked medicines in confidence are liquorsaturated ligustrum lucidum with scutellaria barbata with atractylodes macrocephala, poria cocos with coix seed with atractylodes macrocephala, liquorsaturated ligustrum lucidum with coix seed with atractylodes macrocephala, and poria cocos with scutellaria barbata with atractylodes macrocephala. The top five quadrlinked medicine in confidence are poria cocos with liquorsaturated ligustrum lucidum with coix seed with atractylodes macrocephala, poria cocos with liquorsaturated ligustrum lucidum with scutellaria barbata with atractylodes macrocephala, hedyotis diffusa with poria cocos with liquorsaturated ligustrum lucidum with atractylodes macrocephala, codonopsis pilosula with poria cocos with liquorsaturated ligustrum lucidum with astragalus membranaceus, and codonopsis pilosula with atractylodes macrocephala with liquorsaturated ligustrum lucidum with astragalus membranaceus. Conclusion: The main pathogenesis of consolidation period of breast cancer is Qi deficiency and toxin stagnation, and the most important treatment is enriching Qi and detoxify, strengthening the spleen and tonifying the kidney.

Research on treatment and medication rule of insomnia treated by TCM based on data mining Objectives: Based on data mining technology, this research explores the rules of traditional Chinese medicine treatment of insomnia and obtains some significant medical implication through data mining. Technology or Method: Nearly 6,000 electronic medical records of Chinese medicine clinics are selected, and data preprocessing is performed. Then, Ariporiu0027s data mining algorithm is used to analyze prescription medication rule, and the association between symptoms and drugs. Finally, a network diagram is built through complex network analysis. Results: There are 631 insomnia cases that met the criteria, 22 typical symptoms, and 330 drugs. There are 6 symptom association items with a confidence level of more than 30%, 46 drug association items with a confidence level of more than 75%, and 40 symptom association rules with a confidence level of more than 40%. Conclusions: The results showed the rule of medication used in the diagnosis and treatment of insomnia in Chinese medicine outpatients, and found the association between prescription medication rules and symptomatic drugs. Clinical or Biological Impact: This paper provides a reference to the clinical diagnosis and treatment of young physicians, and provides a reference to the development of new drugs. And to promote the development of the theory and practice of traditional Chinese medicine prescriptions is conducive to inheriting and carrying forward the experience and advantages of Chinese medicine treatment of insomnia.