Giải quần vợt Pháp Mở rộng 2021 – Đơn nữ

Barbora Krejčíková
| runner = Anastasia Pavlyuchenkova
| score = 6–1, 2–6, 6–4
| draw = 128 (12 / 8 )
| seeds = 32
| before_name = Giải quần vợt Pháp Mở rộng – Đơn nữ
| after_name = Giải quần vợt Pháp Mở rộng – Đơn nữ
| type = giaiquanvotphapmorong
}}

Barbora Krejčíková là nhà vô địch, đánh bại Anastasia Pavlyuchenkova trong trận chung kết, 6–1, 2–6, 6–4. Đây là danh hiệu Grand Slam đầu tiên của Krejčíková ở nội dung đơn, và là danh hiệu Grand Slam thứ 6 trong tổng số. Krejčíková vô địch sau khi cứu 1 match point trong trận bán kết trước Maria Sakkari, trở thành tay vợt đầu tiên sau Justine Henin vào năm 2005, và là tay vợt nữ thứ 3 trong Kỷ nguyên Mở, vô địch Giải quần vợt Pháp Mở rộng sau khi cứu 1 match point. Đây cũng là giải đấu lớn thứ 2 liên tiếp nhà vô địch nữ cứu ít nhất 1 match point, sau Naomi Osaka cứu 2 match points để vô địch Giải quần vợt Úc Mở rộng 2021. Krejčíková trở thành tay vợt Séc đầu tiên giành một danh hiệu đơn Grand Slam sau Petra Kvitová tại Giải quần vợt Wimbledon 2014, và là tay vợt đầu tiên giành danh hiệu đơn nữ tại Roland Garros sau Hana Mandlíková vào năm 1981.}}

Krejčíková trở thành tay vợt đầu tiên thắng trận chung kết ở cả nội dung đơn và đôi tại cùng một giải Grand Slam sau Serena Williams tại Giải quần vợt Wimbledon 2016, và là tay vợt đầu tiên tại Giải quần vợt Pháp Mở rộng sau Mary Pierce vào năm 2000. Pavlyuchenkova vào trận chung kết giải đấu lớn đầu tiên sau khi đã tham dự 52 vòng đấu chính giải Grand Slam, phá vỡ kỷ lục trước đó của Flavia Pennetta vào năm 2015. Cô trở thành tay vợt Nga đầu tiên vào trận chung kết đơn Grand Slam sau Maria Sharapova tại Giải quần vợt Úc Mở rộng 2015, và là tay vợt đầu tiên vào trận chung kết Pháp Mở rộng sau Sharapova vào năm 2014.

Iga Świątek là đương kim vô địch, nhưng thua ở vòng tứ kết trước Sakkari. Trận thua của Świątek là năm thứ 14 liên tiếp nhà đương kim vô địch không bảo vệ thành công danh hiệu, với Henin là tay vợt nữ cuối cùng làm được vào năm 2007. Đây cũng là lần thứ 6 liên tiếp Pháp Mở rộng có nhà vô địch đầu tiên, và là lần thứ 5 trong Kỷ nguyên Mở tay vợt xếp ngoài top 10 vô địch. Trận thua của Świątek cũng đảm bảo đây là lần đầu tiên Pháp Mở rộng và giải Grand Slam thứ 2 trong Kỷ nguyên Mở có 4 tay vợt lần đầu vào vòng bán kết giải Grand Slam. Lần duy nhất trước đó tại Giải quần vợt Úc Mở rộng 1978. Đây trở thành giải quần vợt lớn đầu tiên trong Kỷ nguyên Mở có 6 tay vợt lần đầu vào vòng tứ kết một giải Grand Slam.

Ashleigh Barty và Naomi Osaka cạnh tranh vị trí số 1 đơn WTA khi giải đấu bắt đầu. Barty giữ nguyên thứ hạng sau khi Osaka rút lui ở vòng 2.

Serena Williams trở thành tay vợt nữ cao tuổi nhất vào vòng 4 tại Pháp Mở rộng trong Kỷ nguyên Mở; một kỷ lục trước đó do chị cô Venus nắm giữ. Sakkari và Tamara Zidanšek trở thành tay vợt nữ người Hy Lạp và người Slovenia đầu tiên vào vòng tứ kết và bán kết nội dung đơn tại một giải Grand Slam. Coco Gauff trở thành tay vợt trẻ nhất vào vòng tứ kết một giải Grand Slam sau Nicole Vaidišová tại Giải quần vợt Pháp Mở rộng 2006.

Hạt giống
Ashleigh Barty (Vòng 2, bỏ cuộc)
Naomi Osaka (Vòng 2, rút lui)
Aryna Sabalenka (Vòng 3)
Sofia Kenin (Vòng 4)
Elina Svitolina (Vòng 3)
Bianca Andreescu (Vòng 1)
Serena Williams (Vòng 4)
Iga Świątek (Tứ kết)
Karolína Plíšková (Vòng 2)
Belinda Bencic (Vòng 2)
Petra Kvitová (Vòng 2, rút lui)
Garbiñe Muguruza (Vòng 1)
Jennifer Brady (Vòng 3, bỏ cuộc)
Elise Mertens (Vòng 3)
Victoria Azarenka (Vòng 4)
Kiki Bertens (Vòng 1)
Maria Sakkari (Bán kết)
Karolína Muchová (Vòng 3)
Johanna Konta (Vòng 1)
Markéta Vondroušová (Vòng 4)
Elena Rybakina (Tứ kết)
Petra Martić (Vòng 1)
Madison Keys (Vòng 3)
Coco Gauff (Tứ kết)
Ons Jabeur (Vòng 4)
Angelique Kerber (Vòng 1)
Alison Riske (Rút lui)
Jessica Pegula (Vòng 3)
Veronika Kudermetova (Vòng 2)
Anett Kontaveit (Vòng 3)
Anastasia Pavlyuchenkova (Chung kết)
Ekaterina Alexandrova (Vòng 2)
Paula Badosa (Tứ kết)
}}

Kết quả

|}
Chung kết
Coco Gauff
| RD1-score1-1=66
| RD1-score1-2=3
| RD1-score1-3=
| RD1-seed2=&nbsp;
| RD1-team2= Barbora Krejčíková
| RD1-score2-1=78
| RD1-score2-2=6
| RD1-score2-3=

| RD1-seed3=17
| RD1-team3= Maria Sakkari
| RD1-score3-1=6
| RD1-score3-2=6
| RD1-score3-3=
| RD1-seed4=8
| RD1-team4= Iga Świątek
| RD1-score4-1=4
| RD1-score4-2=4
| RD1-score4-3=

| RD1-seed5=21
| RD1-team5= Elena Rybakina
| RD1-score5-1=77
| RD1-score5-2=2
| RD1-score5-3=7
| RD1-seed6=31
| RD1-team6= Anastasia Pavlyuchenkova
| RD1-score6-1=62
| RD1-score6-2=6
| RD1-score6-3=9

| RD1-seed7=&nbsp;
| RD1-team7= Tamara Zidanšek
| RD1-score7-1=7
| RD1-score7-2=4
| RD1-score7-3=8
| RD1-seed8=33
| RD1-team8= Paula Badosa
| RD1-score8-1=5
| RD1-score8-2=6
| RD1-score8-3=6

| RD2-seed1=&nbsp;
| RD2-team1= Barbora Krejčíková
| RD2-score1-1=7
| RD2-score1-2=4
| RD2-score1-3=9
| RD2-seed2=17
| RD2-team2= Maria Sakkari
| RD2-score2-1=5
| RD2-score2-2=6
| RD2-score2-3=7

| RD2-seed3=31
| RD2-team3= Anastasia Pavlyuchenkova
| RD2-score3-1=7
| RD2-score3-2=6
| RD2-score3-3=
| RD2-seed4=
| RD2-team4= Tamara Zidanšek
| RD2-score4-1=5
| RD2-score4-2=3
| RD2-score4-3=

| RD3-seed1=
| RD3-team1= Barbora Krejčíková
| RD3-score1-1=6
| RD3-score1-2=2
| RD3-score1-3=6
| RD3-seed2=31
| RD3-team2= Anastasia Pavlyuchenkova
| RD3-score2-1=1
| RD3-score2-2=6
| RD3-score2-3=4
}}

Nửa trên
Nhánh 1
A Barty
| RD1-score01-1=6
| RD1-score01-2=3
| RD1-score01-3=6
| RD1-seed02=
| RD1-team02= B Pera
| RD1-score02-1=4
| RD1-score02-2=6
| RD1-score02-3=2

| RD1-seed03=
| RD1-team03= M Linette
| RD1-score03-1=6
| RD1-score03-2=6
| RD1-score03-3=
| RD1-seed04=WC
| RD1-team04= C Paquet
| RD1-score04-1=3
| RD1-score04-2=3
| RD1-score04-3=

| RD1-seed05=Q
| RD1-team05= I Bara
| RD1-score05-1=65
| RD1-score05-2=2
| RD1-score05-3=
| RD1-seed06=WC
| RD1-team06= A Sharma
| RD1-score06-1=77
| RD1-score06-2=6
| RD1-score06-3=

| RD1-seed07=
| RD1-team07= Y Putintseva
| RD1-score07-1=5
| RD1-score07-2=2
| RD1-score07-3=
| RD1-seed08=25
| RD1-team08= O Jabeur
| RD1-score08-1=7
| RD1-score08-2=6
| RD1-score08-3=

| RD1-seed09=24
| RD1-team09= C Gauff
| RD1-score09-1=713
| RD1-score09-2=6
| RD1-score09-3=
| RD1-seed10=Q
| RD1-team10= A Krunić
| RD1-score10-1=611
| RD1-score10-2=4
| RD1-score10-3=

| RD1-seed11=
| RD1-team11= Q Wang
| RD1-score11-1=2
| RD1-score11-2=6
| RD1-score11-3=7
| RD1-seed12=
| RD1-team12= S-w Hsieh
| RD1-score12-1=6
| RD1-score12-2=4
| RD1-score12-3=5

| RD1-seed13=Q
| RD1-team13= E-s Liang
| RD1-score13-1=1
| RD1-score13-2=6
| RD1-score13-3=4
| RD1-seed14=
| RD1-team14= F Ferro
| RD1-score14-1=6
| RD1-score14-2=1
| RD1-score14-3=6

| RD1-seed15=
| RD1-team15= A Sevastova
| RD1-score15-1=3
| RD1-score15-2=3
| RD1-score15-3=
| RD1-seed16=13
| RD1-team16= J Brady
| RD1-score16-1=6
| RD1-score16-2=6
| RD1-score16-3=

| RD2-seed01=1
| RD2-team01= A Barty
| RD2-score01-1=1
| RD2-score01-2=2r
| RD2-score01-3=
| RD2-seed02=
| RD2-team02= M Linette
| RD2-score02-1=6
| RD2-score02-2=2
| RD2-score02-3=

| RD2-seed03=WC
| RD2-team03= A Sharma
| RD2-score03-1=2
| RD2-score03-2=4
| RD2-score03-3=
| RD2-seed04=25
| RD2-team04= O Jabeur
| RD2-score04-1=6
| RD2-score04-2=6
| RD2-score04-3=

| RD2-seed05=24
| RD2-team05= C Gauff
| RD2-score05-1=6
| RD2-score05-2=77
| RD2-score05-3=
| RD2-seed06=
| RD2-team06= Q Wang
| RD2-score06-1=3
| RD2-score06-2=61
| RD2-score06-3=

| RD2-seed07=
| RD2-team07= F Ferro
| RD2-score07-1=4
| RD2-score07-2=6
| RD2-score07-3=5
| RD2-seed08=13
| RD2-team08= J Brady
| RD2-score08-1=6
| RD2-score08-2=2
| RD2-score08-3=7

| RD3-seed01=
| RD3-team01= M Linette
| RD3-score01-1=6
| RD3-score01-2=0
| RD3-score01-3=1
| RD3-seed02=25
| RD3-team02= O Jabeur
| RD3-score02-1=3
| RD3-score02-2=6
| RD3-score02-3=6

| RD3-seed03=24
| RD3-team03= C Gauff
| RD3-score03-1=6
| RD3-score03-2=0
| RD3-score03-3=
| RD3-seed04=13
| RD3-team04= J Brady
| RD3-score04-1=1
| RD3-score04-2=0r
| RD3-score04-3=

| RD4-seed01=25
| RD4-team01= O Jabeur
| RD4-score01-1=3
| RD4-score01-2=1
| RD4-score01-3=
| RD4-seed02=24
| RD4-team02= C Gauff
| RD4-score02-1=6
| RD4-score02-2=6
| RD4-score02-3=
}}

Nhánh 2
Ka Plíšková
| RD1-score01-1=7
| RD1-score01-2=6
| RD1-score01-3=
| RD1-seed02=
| RD1-team02= D Vekić
| RD1-score02-1=5
| RD1-score02-2=4
| RD1-score02-3=

| RD1-seed03=
| RD1-team03= C Suárez Navarro
| RD1-score03-1=6
| RD1-score03-2=64
| RD1-score03-3=4
| RD1-seed04=
| RD1-team04= S Stephens
| RD1-score04-1=3
| RD1-score04-2=77
| RD1-score04-3=6

| RD1-seed05=Q
| RD1-team05= V Lepchenko
| RD1-score05-1=6
| RD1-score05-2=6
| RD1-score05-3=
| RD1-seed06=
| RD1-team06= S Zhang
| RD1-score06-1=3
| RD1-score06-2=3
| RD1-score06-3=

| RD1-seed07=PR
| RD1-team07= A Petkovic
| RD1-score07-1=6
| RD1-score07-2=3
| RD1-score07-3=4
| RD1-seed08=18
| RD1-team08= K Muchová
| RD1-score08-1=1
| RD1-score08-2=6
| RD1-score08-3=6

| RD1-seed09=32
| RD1-team09= E Alexandrova
| RD1-score09-1=6
| RD1-score09-2=6
| RD1-score09-3=
| RD1-seed10=
| RD1-team10= V Williams
| RD1-score10-1=3
| RD1-score10-2=1
| RD1-score10-3=

| RD1-seed11=
| RD1-team11= B Krejčíková
| RD1-score11-1=5
| RD1-score11-2=6
| RD1-score11-3=6
| RD1-seed12=
| RD1-team12= Kr Plíšková
| RD1-score12-1=7
| RD1-score12-2=4
| RD1-score12-3=2

| RD1-seed13=
| RD1-team13= A Li
| RD1-score13-1=6
| RD1-score13-2=6
| RD1-score13-3=
| RD1-seed14=
| RD1-team14= M Gasparyan
| RD1-score14-1=0
| RD1-score14-2=1
| RD1-score14-3=

| RD1-seed15=WC
| RD1-team15= O Babel
| RD1-score15-1=2
| RD1-score15-2=5
| RD1-score15-3=
| RD1-seed16=5
| RD1-team16= E Svitolina
| RD1-score16-1=6
| RD1-score16-2=7
| RD1-score16-3=

| RD2-seed01=9
| RD2-team01= Ka Plíšková
| RD2-score01-1=5
| RD2-score01-2=1
| RD2-score01-3=
| RD2-seed02=
| RD2-team02= S Stephens
| RD2-score02-1=7
| RD2-score02-2=6
| RD2-score02-3=

| RD2-seed03=Q
| RD2-team03= V Lepchenko
| RD2-score03-1=3
| RD2-score03-2=4
| RD2-score03-3=
| RD2-seed04=18
| RD2-team04= K Muchová
| RD2-score04-1=6
| RD2-score04-2=6
| RD2-score04-3=

| RD2-seed05=32
| RD2-team05= E Alexandrova
| RD2-score05-1=2
| RD2-score05-2=3
| RD2-score05-3=
| RD2-seed06=
| RD2-team06= B Krejčíková
| RD2-score06-1=6
| RD2-score06-2=6
| RD2-score06-3=

| RD2-seed07=
| RD2-team07= A Li
| RD2-score07-1=0
| RD2-score07-2=4
| RD2-score07-3=
| RD2-seed08=5
| RD2-team08= E Svitolina
| RD2-score08-1=6
| RD2-score08-2=6
| RD2-score08-3=

| RD3-seed01=
| RD3-team01= S Stephens
| RD3-score01-1=6
| RD3-score01-2=7
| RD3-score01-3=
| RD3-seed02=18
| RD3-team02= K Muchová
| RD3-score02-1=3
| RD3-score02-2=5
| RD3-score02-3=

| RD3-seed03=
| RD3-team03= B Krejčíková
| RD3-score03-1=6
| RD3-score03-2=6
| RD3-score03-3=
| RD3-seed04=5
| RD3-team04= E Svitolina
| RD3-score04-1=3
| RD3-score04-2=2
| RD3-score04-3=

| RD4-seed01=
| RD4-team01= S Stephens
| RD4-score01-1=2
| RD4-score01-2=0
| RD4-score01-3=
| RD4-seed02=
| RD4-team02= B Krejčíková
| RD4-score02-1=6
| RD4-score02-2=6
| RD4-score02-3=
}}

Nhánh 3
S Kenin
| RD1-score01-1=6
| RD1-score01-2=4
| RD1-score01-3=6
| RD1-seed02=
| RD1-team02= J Ostapenko
| RD1-score02-1=4
| RD1-score02-2=6
| RD1-score02-3=3

| RD1-seed03=Q
| RD1-team03= H Baptiste
| RD1-score03-1=6
| RD1-score03-2=6
| RD1-score03-3=
| RD1-seed04=
| RD1-team04= A Blinkova
| RD1-score04-1=1
| RD1-score04-2=4
| RD1-score04-3=

| RD1-seed05=
| RD1-team05= T Martincová
| RD1-score05-1=6
| RD1-score05-2=78
| RD1-score05-3=
| RD1-seed06=PR
| RD1-team06= I Jorović
| RD1-score06-1=3
| RD1-score06-2=66
| RD1-score06-3=

| RD1-seed07=
| RD1-team07= L Zhu
| RD1-score07-1=4
| RD1-score07-2=6
| RD1-score07-3=4
| RD1-seed08=28
| RD1-team08= J Pegula
| RD1-score08-1=6
| RD1-score08-2=4
| RD1-score08-3=6

| RD1-seed09=17
| RD1-team09= M Sakkari
| RD1-score09-1=6
| RD1-score09-2=6
| RD1-score09-3=
| RD1-seed10=Q
| RD1-team10= K Zavatska
| RD1-score10-1=4
| RD1-score10-2=1
| RD1-score10-3=

| RD1-seed11=
| RD1-team11= J Paolini
| RD1-score11-1=7
| RD1-score11-2=6
| RD1-score11-3=
| RD1-seed12=Q
| RD1-team12= S Vögele
| RD1-score12-1=5
| RD1-score12-2=1
| RD1-score12-3=

| RD1-seed13=
| RD1-team13= H Watson
| RD1-score13-1=4
| RD1-score13-2=5
| RD1-score13-3=
| RD1-seed14=
| RD1-team14= Z Diyas
| RD1-score14-1=6
| RD1-score14-2=7
| RD1-score14-3=

| RD1-seed15=Q
| RD1-team15= S Sanders
| RD1-score15-1=4
| RD1-score15-2=1
| RD1-score15-3=
| RD1-seed16=14
| RD1-team16= E Mertens
| RD1-score16-1=6
| RD1-score16-2=6
| RD1-score16-3=

| RD2-seed01=4
| RD2-team01= S Kenin
| RD2-score01-1=7
| RD2-score01-2=6
| RD2-score01-3=
| RD2-seed02=Q
| RD2-team02= H Baptiste
| RD2-score02-1=5
| RD2-score02-2=3
| RD2-score02-3=

| RD2-seed03=
| RD2-team03= T Martincová
| RD2-score03-1=3
| RD2-score03-2=3
| RD2-score03-3=
| RD2-seed04=28
| RD2-team04= J Pegula
| RD2-score04-1=6
| RD2-score04-2=6
| RD2-score04-3=

| RD2-seed05=17
| RD2-team05= M Sakkari
| RD2-score05-1=6
| RD2-score05-2=6
| RD2-score05-3=
| RD2-seed06=
| RD2-team06= J Paolini
| RD2-score06-1=2
| RD2-score06-2=3
| RD2-score06-3=

| RD2-seed07=
| RD2-team07= Z Diyas
| RD2-score07-1=6
| RD2-score07-2=2
| RD2-score07-3=4
| RD2-seed08=14
| RD2-team08= E Mertens
| RD2-score08-1=4
| RD2-score08-2=6
| RD2-score08-3=6

| RD3-seed01=4
| RD3-team01= S Kenin
| RD3-score01-1=4
| RD3-score01-2=6
| RD3-score01-3=6
| RD3-seed02=28
| RD3-team02= J Pegula
| RD3-score02-1=6
| RD3-score02-2=1
| RD3-score02-3=4

| RD3-seed03=17
| RD3-team03= M Sakkari
| RD3-score03-1=7
| RD3-score03-2=62
| RD3-score03-3=6
| RD3-seed04=14
| RD3-team04= E Mertens
| RD3-score04-1=5
| RD3-score04-2=77
| RD3-score04-3=2

| RD4-seed01=4
| RD4-team01= S Kenin
| RD4-score01-1=1
| RD4-score01-2=3
| RD4-score01-3=
| RD4-seed02=17
| RD4-team02= M Sakkari
| RD4-score02-1=6
| RD4-score02-2=6
| RD4-score02-3=
}}

Nhánh 4
G Muguruza
| RD1-score01-1=1
| RD1-score01-2=4
| RD1-score01-3=
| RD1-seed02=
| RD1-team02= M Kostyuk
| RD1-score02-1=6
| RD1-score02-2=6
| RD1-score02-3=

| RD1-seed03=
| RD1-team03= S Zheng
| RD1-score03-1=4
| RD1-score03-2=6
| RD1-score03-3=6
| RD1-seed04=
| RD1-team04= S Sorribes Tormo
| RD1-score04-1=6
| RD1-score04-2=4
| RD1-score04-3=4

| RD1-seed05=Q
| RD1-team05= L Arruabarrena
| RD1-score05-1=2
| RD1-score05-2=3
| RD1-score05-3=
| RD1-seed06=
| RD1-team06= V Gracheva
| RD1-score06-1=6
| RD1-score06-2=6
| RD1-score06-3=

| RD1-seed07=
| RD1-team07= C Giorgi
| RD1-score07-1=6
| RD1-score07-2=65
| RD1-score07-3=6
| RD1-seed08=22
| RD1-team08= P Martić
| RD1-score08-1=2
| RD1-score08-2=77
| RD1-score08-3=4

| RD1-seed09=30
| RD1-team09= A Kontaveit
| RD1-score09-1=64
| RD1-score09-2=77
| RD1-score09-3=6
| RD1-seed10=
| RD1-team10= V Golubic
| RD1-score10-1=77
| RD1-score10-2=65
| RD1-score10-3=0

| RD1-seed11=Q
| RD1-team11= AK Schmiedlová
| RD1-score11-1=4
| RD1-score11-2=0
| RD1-score11-3=
| RD1-seed12=
| RD1-team12= K Mladenovic
| RD1-score12-1=6
| RD1-score12-2=6
| RD1-score12-3=

| RD1-seed13=
| RD1-team13= R Peterson
| RD1-score13-1=63
| RD1-score13-2=710
| RD1-score13-3=6
| RD1-seed14=
| RD1-team14= S Rogers
| RD1-score14-1=77
| RD1-score14-2=68
| RD1-score14-3=2

| RD1-seed15=
| RD1-team15= K Juvan
| RD1-score15-1=0
| RD1-score15-2=5
| RD1-score15-3=
| RD1-seed16=8
| RD1-team16= I Świątek
| RD1-score16-1=6
| RD1-score16-2=7
| RD1-score16-3=

| RD2-seed01=
| RD2-team01= M Kostyuk
| RD2-score01-1=6
| RD2-score01-2=6
| RD2-score01-3=
| RD2-seed02=
| RD2-team02= S Zheng
| RD2-score02-1=3
| RD2-score02-2=4
| RD2-score02-3=

| RD2-seed03=
| RD2-team03= V Gracheva
| RD2-score03-1=7
| RD2-score03-2=1
| RD2-score03-3=6
| RD2-seed04=
| RD2-team04= C Giorgi
| RD2-score04-1=5
| RD2-score04-2=6
| RD2-score04-3=2

| RD2-seed05=30
| RD2-team05= A Kontaveit
| RD2-score05-1=6
| RD2-score05-2=6
| RD2-score05-3=
| RD2-seed06=
| RD2-team06= K Mladenovic
| RD2-score06-1=2
| RD2-score06-2=0
| RD2-score06-3=

| RD2-seed07=
| RD2-team07= R Peterson
| RD2-score07-1=1
| RD2-score07-2=1
| RD2-score07-3=
| RD2-seed08=8
| RD2-team08= I Świątek
| RD2-score08-1=6
| RD2-score08-2=6
| RD2-score08-3=

| RD3-seed01=
| RD3-team01= M Kostyuk
| RD3-score01-1=6
| RD3-score01-2=6
| RD3-score01-3=
| RD3-seed02=
| RD3-team02= V Gracheva
| RD3-score02-1=1
| RD3-score02-2=2
| RD3-score02-3=

| RD3-seed03=30
| RD3-team03= A Kontaveit
| RD3-score03-1=64
| RD3-score03-2=0
| RD3-score03-3=
| RD3-seed04=8
| RD3-team04= I Świątek
| RD3-score04-1=77
| RD3-score04-2=6
| RD3-score04-3=

| RD4-seed01=
| RD4-team01= M Kostyuk
| RD4-score01-1=3
| RD4-score01-2=4
| RD4-score01-3=
| RD4-seed02=8
| RD4-team02= I Świątek
| RD4-score02-1=6
| RD4-score02-2=6
| RD4-score02-3=
}}

Nửa dưới
Nhánh 5
S Williams
| RD1-score01-1=78
| RD1-score01-2=6
| RD1-score01-3=
| RD1-seed02=
| RD1-team02= I-C Begu
| RD1-score02-1=66
| RD1-score02-2=2
| RD1-score02-3=

| RD1-seed03=
| RD1-team03= A Rus
| RD1-score03-1=5
| RD1-score03-2=5
| RD1-score03-3=
| RD1-seed04=PR
| RD1-team04= M Buzărnescu
| RD1-score04-1=7
| RD1-score04-2=7
| RD1-score04-3=

| RD1-seed05=
| RD1-team05= D Collins
| RD1-score05-1=6
| RD1-score05-2=4
| RD1-score05-3=6
| RD1-seed06=Q
| RD1-team06= Xiyu Wang
| RD1-score06-1=2
| RD1-score06-2=6
| RD1-score06-3=4

| RD1-seed07=Q
| RD1-team07= A Kalinina
| RD1-score07-1=6
| RD1-score07-2=6
| RD1-score07-3=
| RD1-seed08=26
| RD1-team08= A Kerber
| RD1-score08-1=2
| RD1-score08-2=4
| RD1-score08-3=

| RD1-seed09=21
| RD1-team09= E Rybakina
| RD1-score09-1=6
| RD1-score09-2=6
| RD1-score09-3=
| RD1-seed10=WC
| RD1-team10= E Jacquemot
| RD1-score10-1=4
| RD1-score10-2=1
| RD1-score10-3=

| RD1-seed11=
| RD1-team11= N Hibino
| RD1-score11-1=77
| RD1-score11-2=6
| RD1-score11-3=
| RD1-seed12=
| RD1-team12= N Stojanović
| RD1-score12-1=64
| RD1-score12-2=2
| RD1-score12-3=

| RD1-seed13=PR
| RD1-team13= E Vesnina
| RD1-score13-1=6
| RD1-score13-2=6
| RD1-score13-3=
| RD1-seed14=LL
| RD1-team14= O Govortsova
| RD1-score14-1=1
| RD1-score14-2=0
| RD1-score14-3=

| RD1-seed15=Q
| RD1-team15= G Minnen
| RD1-score15-1=77
| RD1-score15-2=65
| RD1-score15-3=1
| RD1-seed16=11
| RD1-team16= P Kvitová
| RD1-score16-1=63
| RD1-score16-2=77
| RD1-score16-3=6

| RD2-seed01=7
| RD2-team01= S Williams
| RD2-score01-1=6
| RD2-score01-2=5
| RD2-score01-3=6
| RD2-seed02=PR
| RD2-team02= M Buzărnescu
| RD2-score02-1=3
| RD2-score02-2=7
| RD2-score02-3=1

| RD2-seed03=
| RD2-team03= D Collins
| RD2-score03-1=6
| RD2-score03-2=6
| RD2-score03-3=
| RD2-seed04=Q
| RD2-team04= A Kalinina
| RD2-score04-1=0
| RD2-score04-2=2
| RD2-score04-3=

| RD2-seed05=21
| RD2-team05= E Rybakina
| RD2-score05-1=6
| RD2-score05-2=6
| RD2-score05-3=
| RD2-seed06=
| RD2-team06= N Hibino
| RD2-score06-1=3
| RD2-score06-2=1
| RD2-score06-3=

| RD2-seed07=PR
| RD2-team07= E Vesnina
| RD2-score07-1=w/o
| RD2-score07-2=
| RD2-score07-3=
| RD2-seed08=11
| RD2-team08= P Kvitová
| RD2-score08-1=
| RD2-score08-2=
| RD2-score08-3=

| RD3-seed01=7
| RD3-team01= S Williams
| RD3-score01-1=6
| RD3-score01-2=6
| RD3-score01-3=
| RD3-seed02=
| RD3-team02= D Collins
| RD3-score02-1=4
| RD3-score02-2=4
| RD3-score02-3=

| RD3-seed03=21
| RD3-team03= E Rybakina
| RD3-score03-1=6
| RD3-score03-2=6
| RD3-score03-3=
| RD3-seed04=PR
| RD3-team04= E Vesnina
| RD3-score04-1=1
| RD3-score04-2=4
| RD3-score04-3=

| RD4-seed01=7
| RD4-team01= S Williams
| RD4-score01-1=3
| RD4-score01-2=5
| RD4-score01-3=
| RD4-seed02=21
| RD4-team02= E Rybakina
| RD4-score02-1=6
| RD4-score02-2=7
| RD4-score02-3=
}}

Nhánh 6
V Azarenka
| RD1-score01-1=6
| RD1-score01-2=2
| RD1-score01-3=6
| RD1-seed02=
| RD1-team02= S Kuznetsova
| RD1-score02-1=4
| RD1-score02-2=6
| RD1-score02-3=3

| RD1-seed03=
| RD1-team03= C Tauson
| RD1-score03-1=6
| RD1-score03-2=6
| RD1-score03-3=
| RD1-seed04=Q
| RD1-team04= E Gorgodze
| RD1-score04-1=4
| RD1-score04-2=2
| RD1-score04-3=

| RD1-seed05=
| RD1-team05= LA Fernandez
| RD1-score05-1=6
| RD1-score05-2=6
| RD1-score05-3=
| RD1-seed06=
| RD1-team06= A Potapova
| RD1-score06-1=2
| RD1-score06-2=1
| RD1-score06-3=

| RD1-seed07=WC
| RD1-team07= O Dodin
| RD1-score07-1=3
| RD1-score07-2=6
| RD1-score07-3=1
| RD1-seed08=23
| RD1-team08= M Keys
| RD1-score08-1=6
| RD1-score08-2=3
| RD1-score08-3=6

| RD1-seed09=31
| RD1-team09= A Pavlyuchenkova
| RD1-score09-1=6
| RD1-score09-2=6
| RD1-score09-3=
| RD1-seed10=
| RD1-team10= C McHale
| RD1-score10-1=4
| RD1-score10-2=0
| RD1-score10-3=

| RD1-seed11=PR
| RD1-team11= K Kozlova
| RD1-score11-1=2
| RD1-score11-2=4
| RD1-score11-3=
| RD1-seed12=
| RD1-team12= A Tomljanović
| RD1-score12-1=6
| RD1-score12-2=6
| RD1-score12-3=

| RD1-seed13=WC
| RD1-team13= D Parry
| RD1-score13-1=3
| RD1-score13-2=6
| RD1-score13-3=3
| RD1-seed14=
| RD1-team14= A Sasnovich
| RD1-score14-1=6
| RD1-score14-2=3
| RD1-score14-3=6

| RD1-seed15=Q
| RD1-team15= A Konjuh
| RD1-score15-1=4
| RD1-score15-2=3
| RD1-score15-3=
| RD1-seed16=3
| RD1-team16= A Sabalenka
| RD1-score16-1=6
| RD1-score16-2=6
| RD1-score16-3=

| RD2-seed01=15
| RD2-team01= V Azarenka
| RD2-score01-1=7
| RD2-score01-2=6
| RD2-score01-3=
| RD2-seed02=
| RD2-team02= C Tauson
| RD2-score02-1=5
| RD2-score02-2=4
| RD2-score02-3=

| RD2-seed03=
| RD2-team03= LA Fernandez
| RD2-score03-1=1
| RD2-score03-2=5
| RD2-score03-3=
| RD2-seed04=23
| RD2-team04= M Keys
| RD2-score04-1=6
| RD2-score04-2=7
| RD2-score04-3=

| RD2-seed05=31
| RD2-team05= A Pavlyuchenkova
| RD2-score05-1=6
| RD2-score05-2=6
| RD2-score05-3=
| RD2-seed06=
| RD2-team06= A Tomljanović
| RD2-score06-1=2
| RD2-score06-2=3
| RD2-score06-3=

| RD2-seed07=
| RD2-team07= A Sasnovich
| RD2-score07-1=5
| RD2-score07-2=3
| RD2-score07-3=
| RD2-seed08=3
| RD2-team08= A Sabalenka
| RD2-score08-1=7
| RD2-score08-2=6
| RD2-score08-3=

| RD3-seed01=15
| RD3-team01= V Azarenka
| RD3-score01-1=6
| RD3-score01-2=6
| RD3-score01-3=
| RD3-seed02=23
| RD3-team02= M Keys
| RD3-score02-1=2
| RD3-score02-2=2
| RD3-score02-3=

| RD3-seed03=31
| RD3-team03= A Pavlyuchenkova
| RD3-score03-1=6
| RD3-score03-2=2
| RD3-score03-3=6
| RD3-seed04=3
| RD3-team04= A Sabalenka
| RD3-score04-1=4
| RD3-score04-2=6
| RD3-score04-3=0

| RD4-seed01=15
| RD4-team01= V Azarenka
| RD4-score01-1=7
| RD4-score01-2=3
| RD4-score01-3=2
| RD4-seed02=31
| RD4-team02= A Pavlyuchenkova
| RD4-score02-1=5
| RD4-score02-2=6
| RD4-score02-3=6
}}

Nhánh 7
B Andreescu
| RD1-score01-1=77
| RD1-score01-2=62
| RD1-score01-3=7
| RD1-seed02=
| RD1-team02= T Zidanšek
| RD1-score02-1=61
| RD1-score02-2=77
| RD1-score02-3=9

| RD1-seed03=
| RD1-team03= M Brengle
| RD1-score03-1=7
| RD1-score03-2=6
| RD1-score03-3=
| RD1-seed04=Q
| RD1-team04= MC Osorio Serrano
| RD1-score04-1=5
| RD1-score04-2=4
| RD1-score04-3=

| RD1-seed05=
| RD1-team05= M Bouzková
| RD1-score05-1=0
| RD1-score05-2=6
| RD1-score05-3=2
| RD1-seed06=
| RD1-team06= K Siniaková
| RD1-score06-1=6
| RD1-score06-2=4
| RD1-score06-3=6

| RD1-seed07=
| RD1-team07= A Anisimova
| RD1-score07-1=65
| RD1-score07-2=1
| RD1-score07-3=
| RD1-seed08=29
| RD1-team08= V Kudermetova
| RD1-score08-1=77
| RD1-score08-2=6
| RD1-score08-3=

| RD1-seed09=19
| RD1-team09= J Konta
| RD1-score09-1=65
| RD1-score09-2=2
| RD1-score09-3=
| RD1-seed10=
| RD1-team10= S Cîrstea
| RD1-score10-1=77
| RD1-score10-2=6
| RD1-score10-3=

| RD1-seed11=
| RD1-team11= A Van Uytvanck
| RD1-score11-1=5
| RD1-score11-2=6
| RD1-score11-3=4
| RD1-seed12=
| RD1-team12= M Trevisan
| RD1-score12-1=7
| RD1-score12-2=4
| RD1-score12-3=6

| RD1-seed13=
| RD1-team13= D Kasatkina
| RD1-score13-1=6
| RD1-score13-2=5
| RD1-score13-3=6
| RD1-seed14=
| RD1-team14= M Doi
| RD1-score14-1=3
| RD1-score14-2=7
| RD1-score14-3=3

| RD1-seed15=
| RD1-team15= N Podoroska
| RD1-score15-1=0
| RD1-score15-2=3
| RD1-score15-3=
| RD1-seed16=10
| RD1-team16= B Bencic
| RD1-score16-1=6
| RD1-score16-2=6
| RD1-score16-3=

| RD2-seed01=
| RD2-team01= T Zidanšek
| RD2-score01-1=6
| RD2-score01-2=6
| RD2-score01-3=
| RD2-seed02=
| RD2-team02= M Brengle
| RD2-score02-1=4
| RD2-score02-2=1
| RD2-score02-3=

| RD2-seed03=
| RD2-team03= K Siniaková
| RD2-score03-1=79
| RD2-score03-2=5
| RD2-score03-3=7
| RD2-seed04=29
| RD2-team04= V Kudermetova
| RD2-score04-1=67
| RD2-score04-2=7
| RD2-score04-3=5

| RD2-seed05=
| RD2-team05= S Cîrstea
| RD2-score05-1=6
| RD2-score05-2=3
| RD2-score05-3=6
| RD2-seed06=
| RD2-team06= M Trevisan
| RD2-score06-1=4
| RD2-score06-2=6
| RD2-score06-3=4

| RD2-seed07=
| RD2-team07= D Kasatkina
| RD2-score07-1=6
| RD2-score07-2=6
| RD2-score07-3=
| RD2-seed08=10
| RD2-team08= B Bencic
| RD2-score08-1=2
| RD2-score08-2=2
| RD2-score08-3=

| RD3-seed01=
| RD3-team01= T Zidanšek
| RD3-score01-1=0
| RD3-score01-2=77
| RD3-score01-3=6
| RD3-seed02=
| RD3-team02= K Siniaková
| RD3-score02-1=6
| RD3-score02-2=65
| RD3-score02-3=2

| RD3-seed03=
| RD3-team03= S Cîrstea
| RD3-score03-1=6
| RD3-score03-2=6
| RD3-score03-3=
| RD3-seed04=
| RD3-team04= D Kasatkina
| RD3-score04-1=3
| RD3-score04-2=2
| RD3-score04-3=

| RD4-seed01=
| RD4-team01= T Zidanšek
| RD4-score01-1=77
| RD4-score01-2=6
| RD4-score01-3=
| RD4-seed02=
| RD4-team02= S Cîrstea
| RD4-score02-1=64
| RD4-score02-2=1
| RD4-score02-3=
}}

Nhánh 8
K Bertens
| RD1-score01-1=1
| RD1-score01-2=6
| RD1-score01-3=4
| RD1-seed02=
| RD1-team02= P Hercog
| RD1-score02-1=6
| RD1-score02-2=3
| RD1-score02-3=6

| RD1-seed03=
| RD1-team03= L Siegemund
| RD1-score03-1=3
| RD1-score03-2=1
| RD1-score03-3=
| RD1-seed04=
| RD1-team04= C Garcia
| RD1-score04-1=6
| RD1-score04-2=6
| RD1-score04-3=

| RD1-seed05=
| RD1-team05= A Cornet
| RD1-score05-1=4
| RD1-score05-2=4
| RD1-score05-3=
| RD1-seed06=WC
| RD1-team06= H Tan
| RD1-score06-1=6
| RD1-score06-2=6
| RD1-score06-3=

| RD1-seed07=
| RD1-team07= K Kanepi
| RD1-score07-1=6
| RD1-score07-2=3
| RD1-score07-3=0
| RD1-seed08=20
| RD1-team08= M Vondroušová
| RD1-score08-1=4
| RD1-score08-2=6
| RD1-score08-3=6

| RD1-seed09=33
| RD1-team09= P Badosa
| RD1-score09-1=6
| RD1-score09-2=77
| RD1-score09-3=
| RD1-seed10=
| RD1-team10= L Davis
| RD1-score10-1=2
| RD1-score10-2=63
| RD1-score10-3=

| RD1-seed11=WC
| RD1-team11= C Burel
| RD1-score11-1=3
| RD1-score11-2=68
| RD1-score11-3=
| RD1-seed12=
| RD1-team12= D Kovinić
| RD1-score12-1=6
| RD1-score12-2=710
| RD1-score12-3=

| RD1-seed13=LL
| RD1-team13= E Cocciaretto
| RD1-score13-1=1
| RD1-score13-2=3
| RD1-score13-3=
| RD1-seed14=
| RD1-team14= A Bogdan
| RD1-score14-1=6
| RD1-score14-2=6
| RD1-score14-3=

| RD1-seed15=
| RD1-team15= PM Țig
| RD1-score15-1=4
| RD1-score15-2=64
| RD1-score15-3=
| RD1-seed16=2
| RD1-team16= N Osaka
| RD1-score16-1=6
| RD1-score16-2=77
| RD1-score16-3=

| RD2-seed01=
| RD2-team01= P Hercog
| RD2-score01-1=7
| RD2-score01-2=6
| RD2-score01-3=
| RD2-seed02=
| RD2-team02= C Garcia
| RD2-score02-1=5
| RD2-score02-2=4
| RD2-score02-3=

| RD2-seed03=WC
| RD2-team03= H Tan
| RD2-score03-1=1
| RD2-score03-2=3
| RD2-score03-3=
| RD2-seed04=20
| RD2-team04= M Vondroušová
| RD2-score04-1=6
| RD2-score04-2=6
| RD2-score04-3=

| RD2-seed05=33
| RD2-team05= P Badosa
| RD2-score05-1=6
| RD2-score05-2=6
| RD2-score05-3=
| RD2-seed06=
| RD2-team06= D Kovinić
| RD2-score06-1=2
| RD2-score06-2=0
| RD2-score06-3=

| RD2-seed07=
| RD2-team07= A Bogdan
| RD2-score07-1=w/o
| RD2-score07-2=
| RD2-score07-3=
| RD2-seed08=2
| RD2-team08= N Osaka
| RD2-score08-1=
| RD2-score08-2=
| RD2-score08-3=

| RD3-seed01=
| RD3-team01= P Hercog
| RD3-score01-1=3
| RD3-score01-2=3
| RD3-score01-3=
| RD3-seed02=20
| RD3-team02= M Vondroušová
| RD3-score02-1=6
| RD3-score02-2=6
| RD3-score02-3=

| RD3-seed03=33
| RD3-team03= P Badosa
| RD3-score03-1=2
| RD3-score03-2=77
| RD3-score03-3=6
| RD3-seed04=
| RD3-team04= A Bogdan
| RD3-score04-1=6
| RD3-score04-2=64
| RD3-score04-3=4

| RD4-seed01=20
| RD4-team01= M Vondroušová
| RD4-score01-1=4
| RD4-score01-2=6
| RD4-score01-3=2
| RD4-seed02=33
| RD4-team02= P Badosa
| RD4-score02-1=6
| RD4-score02-2=3
| RD4-score02-3=6
}}

Vận động viên khác
Đặc cách
Những tay vợt sau đây được đặc cách vào vòng đấu chính.
Océane Babel
Clara Burel
Océane Dodin
Elsa Jacquemot
Chloé Paquet
Diane Parry
Astra Sharma
Harmony Tan
}}

Bảo toàn thứ hạng
Mihaela Buzărnescu (104)
Ivana Jorović (90)
Kateryna Kozlova (104)
Andrea Petkovic (80)
Elena Vesnina (52)
}}

Vượt qua vòng loại

Lara Arruabarrena
Hailey Baptiste
Irina Bara
Ekaterine Gorgodze
Anhelina Kalinina
Ana Konjuh
Aleksandra Krunić
Varvara Lepchenko
Liang En-shuo
Greet Minnen
María Camila Osorio Serrano
Storm Sanders
Anna Karolína Schmiedlová
Stefanie Vögele
Wang Xiyu
Katarina Zavatska
}}

Thua cuộc may mắn
Elisabetta Cocciaretto
Olga Govortsova
}}

Rút lui
;Trước giải đấu
Kirsten Flipkens → thay thế bởi Mihaela Buzărnescu
Simona Halep → thay thế bởi Jasmine Paolini
Alison Riske → thay thế bởi Olga Govortsova
Samantha Stosur → thay thế bởi Ana Bogdan
Barbora Strýcová → thay thế bởi Clara Tauson
Jil Teichmann → thay thế bởi Elisabetta Cocciaretto
Dayana Yastremska → thay thế bởi Kateryna Kozlova

}}

;Trong giải đấu
Naomi Osaka
Petra Kvitová
}}

Bỏ cuộc
Ashleigh Barty
Jennifer Brady
}}

Chú thích

Tham khảo

Liên kết ngoài
Kết quả vòng đấu chính
Giải quần vợt Pháp Mở rộng 2021 - Kết quả nữ tại Roland Garros
Giải quần vợt Pháp Mở rộng 2021 - Kết quả nữ tại Liên đoàn Quần vợt Quốc tế

| title=Grand Slam đơn nữ | years= | after=}}