Giải quần vợt Mỹ Mở rộng 1978 - Đôi nam nữ

Frew McMillan Betty Stöve
| runner = Billie Jean King Ray Ruffels
| score = 6–3, 7-6
| before_name= Giải quần vợt Mỹ Mở rộng – Đôi nam nữ
| after_name= Giải quần vợt Mỹ Mở rộng – Đôi nam nữ
}}

Frew McMillan và Betty Stöve là đương kim vô địch và bảo vệ danh hiệu thành công khi đánh bại Billie Jean King và Ray Ruffels trong trận chung kết, 6–3, 7-6.

Hạt giống
Frew McMillan / Betty Stöve (Vô địch)
Ray Ruffels / Billie Jean King (Chung kết)
Bob Hewitt / Wendy Turnbull (Bán kết)
Chris Kachel / Ilana Kloss (Vòng ba)
}}

Kết quả

Chung kết
Ray Ruffels Billie Jean King
| RD1-score1-1=6
| RD1-score1-2=6
| RD1-score1-3=
| RD1-seed2=
| RD1-team2= Bob Carmichael JoAnne Russell
| RD1-score2-1=0
| RD1-score2-2=1
| RD1-score2-3=

| RD1-seed3=
| RD1-team3= Anand Amritraj Françoise Dürr
| RD1-score3-1=6
| RD1-score3-2=7
| RD1-score3-3=3
| RD1-seed4=
| RD1-team4= Stan Smith Anne Smith
| RD1-score4-1=7
| RD1-score4-2=6
| RD1-score4-3=6

| RD1-seed5=
| RD1-team5= Tom Leonard Pam Teeguarden
| RD1-score5-1=7
| RD1-score5-2=4
| RD1-score5-3=3
| RD1-seed6=3
| RD1-team6= Bob Hewitt Wendy Turnbull
| RD1-score6-1=6
| RD1-score6-2=6
| RD1-score6-3=6

| RD1-seed7=
| RD1-team7= Chris Lewis Helena Anliot
| RD1-score7-1=6
| RD1-score7-2=0
| RD1-score7-3=2
| RD1-seed8=1
| RD1-team8= Frew McMillan Betty Stöve
| RD1-score8-1=3
| RD1-score8-2=6
| RD1-score8-3=6

| RD2-seed1=2
| RD2-team1= Ray Ruffels Billie Jean King
| RD2-score1-1=7
| RD2-score1-2=6
| RD2-score1-3=
| RD2-seed2=
| RD2-team2= Stan Smith Anne Smith
| RD2-score2-1=6
| RD2-score2-2=4
| RD2-score2-3=

| RD2-seed3=3
| RD2-team3= Bob Hewitt Wendy Turnbull
| RD2-score3-1=6
| RD2-score3-2=6
| RD2-score3-3=2
| RD2-seed4=1
| RD2-team4= Frew McMillan Betty Stöve
| RD2-score4-1=4
| RD2-score4-2=7
| RD2-score4-3=6

| RD3-seed1=2
| RD3-team1= Ray Ruffels Billie Jean King
| RD3-score1-1=3
| RD3-score1-2=6
| RD3-score1-3=
| RD3-seed2=1
| RD3-team2= Frew McMillan Betty Stöve
| RD3-score2-1=6
| RD3-score2-2=7
| RD3-score2-3=
}}

Nửa trên

Nhóm 1

R Ruffels BJ King
| RD2-score01-1=6
| RD2-score01-2=6
| RD2-score01-3=6
| RD2-seed02=
| RD2-team02= C Dowdeswell B Nagelsen
| RD2-score02-1=4
| RD2-score02-2=7
| RD2-score02-3=3

| RD2-seed03=
| RD2-team03= P Rennert B Newfield
| RD2-score03-1=5
| RD2-score03-2=2
| RD2-score03-3=
| RD2-seed04=
| RD2-team04= K Warwick R Maršíková
| RD2-score04-1=7
| RD2-score04-2=6
| RD2-score04-3=

| RD2-seed05=
| RD2-team05= B Carmichael J Russell
| RD2-score05-1=6
| RD2-score05-2=6
| RD2-score05-3=
| RD2-seed06=
| RD2-team06= J Kriek B Cuypers
| RD2-score06-1=4
| RD2-score06-2=2
| RD2-score06-3=

| RD2-seed07=
| RD2-team07= B Walts K Shaw
| RD2-score07-1=w/o
| RD2-score07-2=
| RD2-score07-3=
| RD2-seed08=
| RD2-team08= S Menon J Nachand
| RD2-score08-1=
| RD2-score08-2=
| RD2-score08-3=

| RD3-seed01=2
| RD3-team01= R Ruffels BJ King
| RD3-score01-1=7
| RD3-score01-2=6
| RD3-score01-3=
| RD3-seed02=
| RD3-team02= K Warwick R Maršíková
| RD3-score02-1=6
| RD3-score02-2=3
| RD3-score02-3=

| RD3-seed03=
| RD3-team03= B Carmichael J Russell
| RD3-score03-1=6
| RD3-score03-2=7
| RD3-score03-3=
| RD3-seed04=
| RD3-team04= B Walts K Shaw
| RD3-score04-1=4
| RD3-score04-2=5
| RD3-score04-3=

| RD4-seed01=2
| RD4-team01= R Ruffels BJ King
| RD4-score01-1=6
| RD4-score01-2=6
| RD4-score01-3=
| RD4-seed02=
| RD4-team02= B Carmichael J Russell
| RD4-score02-1=0
| RD4-score02-2=1
| RD4-score02-3=
}}

Nhóm 2

A Amritraj A Kiyomura
| RD1-score09-1=6
| RD1-score09-2=3
| RD1-score09-3=2
| RD1-seed10=
| RD1-team10= J McEnroe S Margolin
| RD1-score10-1=4
| RD1-score10-2=6
| RD1-score10-3=6

| RD1-seed11=
| RD1-team11= J Van Linge G Glasgow
| RD1-score11-1=6
| RD1-score11-2=6
| RD1-score11-3=6
| RD1-seed12=
| RD1-team12= G Malin B Hallquist
| RD1-score12-1=7
| RD1-score12-2=3
| RD1-score12-3=4

| RD1-seed13=
| RD1-team13= R Reid K Reid
| RD1-score13-1=
| RD1-score13-2=
| RD1-score13-3=
| RD1-seed14=
| RD1-team14= F Stolle J Anthony
| RD1-score14-1=w/o
| RD1-score14-2=
| RD1-score14-3=

| RD1-seed15=
| RD1-team15= S Smith A Smith
| RD1-score15-1=6
| RD1-score15-2=7
| RD1-score15-3=
| RD1-seed16=
| RD1-team16= J Whitlinger D Fromholtz
| RD1-score16-1=3
| RD1-score16-2=6
| RD1-score16-3=

| RD2-seed01=4
| RD2-team01= C Kachel I Kloss
| RD2-score01-1=6
| RD2-score01-2=3
| RD2-score01-3=6
| RD2-seed02=
| RD2-team02= V Winitsky R Fox
| RD2-score02-1=2
| RD2-score02-2=6
| RD2-score02-3=2

| RD2-seed03=
| RD2-team03= B Smith T Holladay
| RD2-score03-1=1
| RD2-score03-2=3
| RD2-score03-3=
| RD2-seed04=
| RD2-team04= A Amritraj F Dürr
| RD2-score04-1=6
| RD2-score04-2=6
| RD2-score04-3=

| RD2-seed05=
| RD2-team05= J McEnroe S Margolin
| RD2-score05-1=6
| RD2-score05-2=6
| RD2-score05-3=
| RD2-seed06=
| RD2-team06= J Van Linge G Glasgow
| RD2-score06-1=3
| RD2-score06-2=4
| RD2-score06-3=

| RD2-seed07=
| RD2-team07= F Stolle J Anthony
| RD2-score07-1=4
| RD2-score07-2=2
| RD2-score07-3=
| RD2-seed08=
| RD2-team08= S Smith A Smith
| RD2-score08-1=6
| RD2-score08-2=6
| RD2-score08-3=

| RD3-seed01=4
| RD3-team01= C Kachel I Kloss
| RD3-score01-1=2
| RD3-score01-2=4
| RD3-score01-3=
| RD3-seed02=
| RD3-team02= A Amritraj F Dürr
| RD3-score02-1=6
| RD3-score02-2=6
| RD3-score02-3=

| RD3-seed03=
| RD3-team03= J McEnroe S Margolin
| RD3-score03-1=4
| RD3-score03-2=7
| RD3-score03-3=3
| RD3-seed04=
| RD3-team04= S Smith A Smith
| RD3-score04-1=6
| RD3-score04-2=6
| RD3-score04-3=6

| RD4-seed01=
| RD4-team01= A Amritraj F Dürr
| RD4-score01-1=6
| RD4-score01-2=7
| RD4-score01-3=3
| RD4-seed02=
| RD4-team02= S Smith A Smith
| RD4-score02-1=7
| RD4-score02-2=6
| RD4-score02-3=6
}}

Nửa dưới

Nhóm 3

J Marks R Tomanová
| RD1-score01-1=6
| RD1-score01-2=7
| RD1-score01-3=
| RD1-seed02=
| RD1-team02= B Seewagen L Beaven
| RD1-score02-1=3
| RD1-score02-2=6
| RD1-score02-3=

| RD1-seed03=
| RD1-team03= T Leonard P Teeguarden
| RD1-score03-1=w/o
| RD1-score03-2=
| RD1-score03-3=
| RD1-seed04=
| RD1-team04= I Lendl H Strachoňová
| RD1-score04-1=
| RD1-score04-2=
| RD1-score04-3=

| RD1-seed05=
| RD1-team05= F McNair L Hunt
| RD1-score05-1=
| RD1-score05-2=
| RD1-score05-3=
| RD1-seed06=
| RD1-team06= R Fagel C Casabianca
| RD1-score06-1=w/o
| RD1-score06-2=
| RD1-score06-3=

| RD1-seed07=
| RD1-team07= D Crealy P Shriver
| RD1-score07-1=6
| RD1-score07-2=6
| RD1-score07-3=6
| RD1-seed08=
| RD1-team08= V Pecci V Ruzici
| RD1-score08-1=7
| RD1-score08-2=2
| RD1-score08-3=1

| RD2-seed01=
| RD2-team01= J Marks R Tomanová
| RD2-score01-1=6
| RD2-score01-2=2
| RD2-score01-3=4
| RD2-seed02=
| RD2-team02= T Leonard P Teeguarden
| RD2-score02-1=2
| RD2-score02-2=6
| RD2-score02-3=6

| RD2-seed03=
| RD2-team03= R Fagel C Casabianca
| RD2-score03-1=1
| RD2-score03-2=2
| RD2-score03-3=
| RD2-seed04=
| RD2-team04= D Crealy P Shriver
| RD2-score04-1=6
| RD2-score04-2=6
| RD2-score04-3=

| RD2-seed05=
| RD2-team05= W Lloyd P Bostrom
| RD2-score05-1=
| RD2-score05-2=
| RD2-score05-3=
| RD2-seed06=
| RD2-team06= S Denton B Jordan
| RD2-score06-1=w/o
| RD2-score06-2=
| RD2-score06-3=

| RD2-seed07=
| RD2-team07= F González A Spex
| RD2-score07-1=
| RD2-score07-2=
| RD2-score07-3=
| RD2-seed08=3
| RD2-team08= B Hewitt W Turnbull
| RD2-score08-1=w/o
| RD2-score08-2=
| RD2-score08-3=

| RD3-seed01=
| RD3-team01= T Leonard P Teeguarden
| RD3-score01-1=w/o
| RD3-score01-2=
| RD3-score01-3=
| RD3-seed02=
| RD3-team02= D Crealy P Shriver
| RD3-score02-1=
| RD3-score02-2=
| RD3-score02-3=

| RD3-seed03=
| RD3-team03= S Denton B Jordan
| RD3-score03-1=2
| RD3-score03-2=6
| RD3-score03-3=6
| RD3-seed04=3
| RD3-team04= B Hewitt W Turnbull
| RD3-score04-1=6
| RD3-score04-2=4
| RD3-score04-3=7

| RD4-seed01=
| RD4-team01= T Leonard P Teeguarden
| RD4-score01-1=7
| RD4-score01-2=4
| RD4-score01-3=3
| RD4-seed02=3
| RD4-team02= B Hewitt W Turnbull
| RD4-score02-1=6
| RD4-score02-2=6
| RD4-score02-3=6
}}

Nhóm 4

C Lewis H Anliot
| RD2-score01-1=6
| RD2-score01-2=6
| RD2-score01-3=
| RD2-seed02=
| RD2-team02= R Drysdale K Ruddell
| RD2-score02-1=2
| RD2-score02-2=2
| RD2-score02-3=

| RD2-seed03=
| RD2-team03= J Lucas R Richards
| RD2-score03-1=6
| RD2-score03-2=2
| RD2-score03-3=6
| RD2-seed04=
| RD2-team04= P Dent S Leo
| RD2-score04-1=4
| RD2-score04-2=6
| RD2-score04-3=4

| RD2-seed05=
| RD2-team05= A Lucchesi M Louie
| RD2-score05-1=6
| RD2-score05-2=6
| RD2-score05-3=7
| RD2-seed06=
| RD2-team06= H Reid D Desfor
| RD2-score06-1=2
| RD2-score06-2=7
| RD2-score06-3=6

| RD2-seed07=
| RD2-team07= M Edmondson C O'Neil
| RD2-score07-1=4
| RD2-score07-2=2
| RD2-score07-3=
| RD2-seed08=1
| RD2-team08= F McMillan Betty Stöve
| RD2-score08-1=6
| RD2-score08-2=6
| RD2-score08-3=

| RD3-seed01=
| RD3-team01= C Lewis H Anliot
| RD3-score01-1=6
| RD3-score01-2=7
| RD3-score01-3=
| RD3-seed02=
| RD3-team02= J Lucas R Richards
| RD3-score02-1=2
| RD3-score02-2=6
| RD3-score02-3=

| RD3-seed03=
| RD3-team03= A Lucchesi M Louie
| RD3-score03-1=4
| RD3-score03-2=4
| RD3-score03-3=
| RD3-seed04=1
| RD3-team04= F McMillan Betty Stöve
| RD3-score04-1=6
| RD3-score04-2=6
| RD3-score04-3=

| RD4-seed01=
| RD4-team01= C Lewis H Anliot
| RD4-score01-1=6
| RD4-score01-2=0
| RD4-score01-3=2
| RD4-seed02=1
| RD4-team02= F McMillan Betty Stöve
| RD4-score02-1=3
| RD4-score02-2=6
| RD4-score02-3=6
}}

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