umarjan11/Medical-qna huggingface dataset:
Question: What are the symptoms of Glucose transporter type 1 deficiency syndrome ?

Answer: What are the signs and symptoms of Glucose transporter type 1 deficiency syndrome? The most common form of glucose transporter type 1 deficiency syndrome (GLUT1 deficiency syndrome), called the classic type, may be characterized by: Recurrent seizures (epilepsy) beginning in the first months of life Microcephaly (unusually small head size) that develops after birth Developmental delay Intellectual disability Speech and language impairment Movement abnormalities (i.e. involuntary eye movements, spasticity, ataxia, dystonia) Behavioral problems Other signs and symptoms may include headaches, confusion, loss of energy and/or myoclonus (muscle twitches). Approximately 10% of affected people have the non-epileptic form of GLUT1 deficiency syndrome. This form is associated with all the typical symptoms of the condition without seizures. The Human Phenotype Ontology provides the following list of signs and symptoms for Glucose transporter type 1 deficiency syndrome. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medical terms. Signs and Symptoms Approximate number of patients (when available) Seizures 75% Autosomal recessive inheritance 5% Abnormality of metabolism/homeostasis - Ataxia - Autosomal dominant inheritance - Babinski sign - Choreoathetosis - Confusion - Delayed speech and language development - Dysarthria - EEG abnormality - Hemiparesis - Hyperreflexia - Hypoglycorrhachia - Infantile onset - Intellectual disability - Myoclonus - Paralysis - Paroxysmal dystonia - Paroxysmal involuntary eye movements - Paroxysmal lethargy - Phenotypic variability - Postnatal microcephaly - Sleep disturbance - Spasticity - Specific learning disability - The Human Phenotype Ontology (HPO) has collected information on how often a sign or symptom occurs in a condition. Much of this information comes from Orphanet, a European rare disease database. The frequency of a sign or symptom is usually listed as a rough estimate of the percentage of patients who have that feature. The frequency may also be listed as a fraction. The first number of the fraction is how many people had the symptom, and the second number is the total number of people who were examined in one study. For example, a frequency of 25/25 means that in a study of 25 people all patients were found to have that symptom. Because these frequencies are based on a specific study, the fractions may be different if another group of patients are examined. Sometimes, no information on frequency is available. In these cases, the sign or symptom may be rare or common.
Question: What is (are) esophageal atresia/tracheoesophageal fistula ?

Answer: Esophageal atresia/tracheoesophageal fistula (EA/TEF) is a condition resulting from abnormal development before birth of the tube that carries food from the mouth to the stomach (the esophagus). During early development, the esophagus and windpipe (trachea) begin as a single tube that normally divides into the two adjacent passages between four and eight weeks after conception. If this separation does not occur properly, EA/TEF is the result.  In esophageal atresia (EA), the upper esophagus does not connect (atresia) to the lower esophagus and stomach. Almost 90 percent of babies born with esophageal atresia also have a tracheoesophageal fistula (TEF), in which the esophagus and the trachea are abnormally connected, allowing fluids from the esophagus to get into the airways and interfere with breathing. A small number of infants have only one of these abnormalities.  There are several types of EA/TEF, classified by the location of the malformation and the structures that are affected. In more than 80 percent of cases, the lower section of the malformed esophagus is connected to the trachea (EA with a distal TEF). Other possible configurations include having the upper section of the malformed esophagus connected to the trachea (EA with a proximal TEF), connections to the trachea from both the upper and lower sections of the malformed esophagus (EA with proximal and distal TEF), an esophagus that is malformed but does not connect to the trachea (isolated EA), and a connection to the trachea from an otherwise normal esophagus (H-type TEF with no EA).  While EA/TEF arises during fetal development, it generally becomes apparent shortly after birth. Saliva, liquids fed to the infant, or digestive fluids may enter the windpipe through the tracheoesophageal fistula, leading to coughing, respiratory distress, and a bluish appearance of the skin or lips (cyanosis). Esophageal atresia blocks liquids fed to the infant from entering the stomach, so they are spit back up, sometimes along with fluids from the respiratory tract. EA/TEF is a life-threatening condition; affected babies generally require surgery to correct the malformation in order to allow feeding and prevent lung damage from repeated exposure to esophageal fluids.  EA/TEF occurs alone (isolated EA/TEF) in about 40 percent of affected individuals. In other cases it occurs with other birth defects or as part of a genetic syndrome (non-isolated or syndromic EA/TEF).
Question: What to do for Diverticular Disease ?

Answer: The Dietary Guidelines for Americans, 2010, recommends a dietary fiber intake of 14 grams per 1,000 calories consumed. For instance, for a 2,000-calorie diet, the fiber recommendation is 28 grams per day. The amount of fiber in a food is listed on the foods nutrition facts label. Some of the best sources of fiber include fruits; vegetables, particularly starchy ones; and whole grains. A health care provider or dietitian can help a person learn how to add more high-fiber foods into the diet.
                
Fiber-rich Foods        Beans, cereals, and breads    Amount of fiber        1/2 cup of navy beans    9.5 grams        1/2 cup of kidney beans    8.2 grams        1/2 cup of black beans    7.5 grams        Whole-grain cereal, cold        1/2 cup of All-Bran    9.6 grams        3/4 cup of Total    2.4 grams        3/4 cup of Post Bran Flakes    5.3 grams        1 packet of whole-grain cereal, hot (oatmeal, Wheatena)    3.0 grams        1 whole-wheat English muffin    4.4 grams        Fruits        1 medium apple, with skin    3.3 grams        1 medium pear, with skin    4.3 grams        1/2 cup of raspberries    4.0 grams        1/2 cup of stewed prunes    3.8 grams        Vegetables        1/2 cup of winter squash    2.9 grams         1 medium sweet potato, with skin    4.8 grams        1/2 cup of green peas    4.4 grams        1 medium potato, with skin    3.8 grams        1/2 cup of mixed vegetables    4.0 grams        1 cup of cauliflower    2.5 grams        1/2 cup of spinach    3.5 grams        1/2 cup of turnip greens    2.5 grams
                
Scientists now believe that people with diverticular disease do not need to eliminate certain foods from their diet. In the past, health care providers recommended that people with diverticular disease avoid nuts, popcorn, and sunflower, pumpkin, caraway, and sesame seeds because they thought food particles could enter, block, or irritate the diverticula. However, recent data suggest that these foods are not harmful.5 The seeds in tomatoes, zucchini, cucumbers, strawberries, and raspberries, as well as poppy seeds, are also fine to eat. Nonetheless, people with diverticular disease may differ in the amounts and types of foods that worsen their symptoms.
Question: Who is at risk for Cataract? ?

Answer: There are several things you can do to lower your risk for cataract. They include - having regular eye exams  - quitting smoking  - wearing sunglasses  - taking care of other health problems  - maintaining a healthy weight  - choosing a healthy diet. having regular eye exams quitting smoking wearing sunglasses taking care of other health problems maintaining a healthy weight choosing a healthy diet. Get Regular Eye Exams Be sure to have regular comprehensive eye exams. If you are age 60 or older, you should have a comprehensive dilated eye exam at least once a year. Eye exams can help detect cataracts and other age-related eye problems at their earliest stages. In addition to cataract, your eye care professional can check for signs of age-related macular degeneration, glaucoma, and other vision disorders. For many eye diseases, early treatment may save your sight. For more on comprehensive eye exams, see the chapter on Symptoms and Detection. Quit Smoking Ask your doctor for help to stop smoking. Medications, counseling and other strategies are available to help you. Wear Sunglasses Ultraviolet light from the sun may contribute to the development of cataracts. Wear sunglasses that block ultraviolet B (UVB) rays when you're outdoors. Take Care of Other Health Problems Follow your treatment plan if you have diabetes or other medical conditions that can increase your risk of cataracts. Maintain a Healthy Weight If your current weight is a healthy one, work to maintain it by exercising most days of the week. If you're overweight or obese, work to lose weight slowly by reducing your calorie intake and increasing the amount of exercise you get each day. Choose a Healthy Diet Choose a healthy diet that includes plenty of fruits and vegetables. Adding a variety of colorful fruits and vegetables to your diet ensures that you're getting a lot of vitamins and nutrients. Fruits and vegetables are full of antioxidants, which in theory could prevent damage to your eye's lens. Studies haven't proven that antioxidants in pill form can prevent cataracts. But fruits and vegetables have many proven health benefits and are a safe way to increase the amount of vitamins in your diet. Choose a Healthy Diet Choose a healthy diet that includes plenty of fruits and vegetables. Adding a variety of colorful fruits and vegetables to your diet ensures that you're getting a lot of vitamins and nutrients. Fruits and vegetables are full of antioxidants, which in theory could prevent damage to your eye's lens. Studies haven't proven that antioxidants in pill form can prevent cataracts. But fruits and vegetables have many proven health benefits and are a safe way to increase the amount of vitamins in your diet.
Question: What are the symptoms of Retinitis pigmentosa, deafness, mental retardation, and hypogonadism ?

Answer: What are the signs and symptoms of Retinitis pigmentosa, deafness, mental retardation, and hypogonadism? The Human Phenotype Ontology provides the following list of signs and symptoms for Retinitis pigmentosa, deafness, mental retardation, and hypogonadism. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medical terms. Signs and Symptoms Approximate number of patients (when available) Acanthosis nigricans 90% Cognitive impairment 90% Gynecomastia 90% Hyperinsulinemia 90% Nystagmus 90% Sensorineural hearing impairment 90% Short stature 90% Type II diabetes mellitus 90% Atypical scarring of skin 50% Brachydactyly syndrome 50% Broad foot 50% Cataract 50% Coarse facial features 50% Cryptorchidism 50% Delayed skeletal maturation 50% Dry skin 50% Obesity 50% Secondary amenorrhea 50% Short toe 50% Visual impairment 50% Cerebral cortical atrophy 7.5% Hyperlordosis 7.5% Kyphosis 7.5% Polycystic ovaries 7.5% Abnormality of the ear - Autosomal recessive inheritance - Broad palm - Cerebellar atrophy - Cerebral atrophy - Elevated hepatic transaminases - Hypergonadotropic hypogonadism - Insulin-resistant diabetes mellitus - Intellectual disability - Pigmentary retinopathy - Rod-cone dystrophy - Sparse hair - Subcapsular cataract - The Human Phenotype Ontology (HPO) has collected information on how often a sign or symptom occurs in a condition. Much of this information comes from Orphanet, a European rare disease database. The frequency of a sign or symptom is usually listed as a rough estimate of the percentage of patients who have that feature. The frequency may also be listed as a fraction. The first number of the fraction is how many people had the symptom, and the second number is the total number of people who were examined in one study. For example, a frequency of 25/25 means that in a study of 25 people all patients were found to have that symptom. Because these frequencies are based on a specific study, the fractions may be different if another group of patients are examined. Sometimes, no information on frequency is available. In these cases, the sign or symptom may be rare or common.
Question: What are the symptoms of Ollier disease ?

Answer: What are the signs and symptoms of Ollier disease? Clinical manifestations in Ollier disease often appear in the first decade of life and usually start with the appearance of palpable bony masses on a finger or a toe, an asymetric shortening of an extremity with limping, and skeletal deformities which may be associated with pathologic fractures. Enchondromas frequently affect the long tubular bones, particularly the tibia, the femur, and/or the fibula; flat bones, especially the pelvis, can also be affected. The lesions may affect multiple bones and are usually asymetrically distributed, exclusively or predominantly affecting one side of the body. Affected bones are often shortened and deformed. Indeed, bone shortening may be the only clinical sign of the disease. These bone shortenings are often associated with bone bending and curving, and may lead to limitations in articular movement. Forearm deformities are frequently encountered. In childhood, the lesions are subjected to pathologic fractures. The Human Phenotype Ontology provides the following list of signs and symptoms for Ollier disease. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medical terms. Signs and Symptoms Approximate number of patients (when available) Abnormality of the metaphyses 90% Cavernous hemangioma 90% Micromelia 90% Osteolysis 90% Visceral angiomatosis 90% Bone pain 50% Limitation of joint mobility 50% Abnormality of coagulation 7.5% Anemia 7.5% Lymphangioma 7.5% Ovarian neoplasm 7.5% Platyspondyly 7.5% Precocious puberty 7.5% Skin ulcer 7.5% Thrombophlebitis 7.5% Chondrosarcoma - Multiple enchondromatosis - The Human Phenotype Ontology (HPO) has collected information on how often a sign or symptom occurs in a condition. Much of this information comes from Orphanet, a European rare disease database. The frequency of a sign or symptom is usually listed as a rough estimate of the percentage of patients who have that feature. The frequency may also be listed as a fraction. The first number of the fraction is how many people had the symptom, and the second number is the total number of people who were examined in one study. For example, a frequency of 25/25 means that in a study of 25 people all patients were found to have that symptom. Because these frequencies are based on a specific study, the fractions may be different if another group of patients are examined. Sometimes, no information on frequency is available. In these cases, the sign or symptom may be rare or common.
Question: What are the symptoms of Metaphyseal acroscyphodysplasia ?

Answer: What are the signs and symptoms of Metaphyseal acroscyphodysplasia? The Human Phenotype Ontology provides the following list of signs and symptoms for Metaphyseal acroscyphodysplasia. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medical terms. Signs and Symptoms Approximate number of patients (when available) Abnormality of the femur 90% Abnormality of the hip bone 90% Abnormality of the metacarpal bones 90% Accelerated skeletal maturation 90% Brachydactyly syndrome 90% Cone-shaped epiphysis 90% Genu varum 90% Micromelia 90% Short stature 90% Short toe 90% Cognitive impairment 50% Depressed nasal ridge 50% Epicanthus 50% Frontal bossing 50% Hypertelorism 50% Telecanthus 50% Malar flattening 7.5% Scoliosis 7.5% Anteverted nares - Autosomal recessive inheritance - Biconcave vertebral bodies - Cone-shaped epiphyses of the phalanges of the hand - Cone-shaped metacarpal epiphyses - Coxa valga - Craniosynostosis - Flat face - Hypoplasia of midface - Hypoplasia of the odontoid process - Intellectual disability - Irregular phalanges - Metaphyseal cupping - Metaphyseal widening - Narrow pelvis bone - Platyspondyly - Prominent forehead - Severe short stature - Short finger - Short humerus - Short metacarpal - Short palm - Short phalanx of finger - Thickened calvaria - Tibial bowing - Wide nasal bridge - The Human Phenotype Ontology (HPO) has collected information on how often a sign or symptom occurs in a condition. Much of this information comes from Orphanet, a European rare disease database. The frequency of a sign or symptom is usually listed as a rough estimate of the percentage of patients who have that feature. The frequency may also be listed as a fraction. The first number of the fraction is how many people had the symptom, and the second number is the total number of people who were examined in one study. For example, a frequency of 25/25 means that in a study of 25 people all patients were found to have that symptom. Because these frequencies are based on a specific study, the fractions may be different if another group of patients are examined. Sometimes, no information on frequency is available. In these cases, the sign or symptom may be rare or common.
Question: What are the complications of Ulcerative Colitis ?

Answer: Complications of ulcerative colitis can include
                
- rectal bleedingwhen ulcers in the intestinal lining open and bleed. Rectal bleeding can cause anemia, which health care providers can treat with diet changes and iron supplements. People who have a large amount of bleeding in the intestine over a short period of time may require surgery to stop the bleeding. Severe bleeding is a rare complication of ulcerative colitis.  - dehydration and malabsorbtion, which occur when the large intestine is unable to absorb fluids and nutrients because of diarrhea and inflammation. Some people may need IV fluids to replace lost nutrients and fluids.  - changes in bones. Some corticosteroid medications taken to treat ulcerative colitis symptoms can cause      - osteoporosisthe loss of bone    - osteopenialow bone density
                
Health care providers will monitor people for bone loss and can recommend calcium and vitamin D supplements and medications to help prevent or slow bone loss.
                
- inflammation in other areas of the body. The immune system can trigger inflammation in the      - joints    - eyes    - skin    - liver
                
Health care providers can treat inflammation by adjusting medications or prescribing new medications.
                
- megacolona serious complication that occurs when inflammation spreads to the deep tissue layers of the large intestine. The large intestine swells and stops working. Megacolon can be a life-threatening complication and most often requires surgery. Megacolon is a rare complication of ulcerative colitis.
                

                
Ulcerative Colitis and Colon Cancer   People with ulcerative colitis may be more likely to develop colon cancer when   - ulcerative colitis affects the entire colon   - a person has ulcerative colitis for at least 8 years   - inflammation is ongoing   - people also have primary sclerosing cholangitis, a condition that affects the liver   - a person is male    People who receive ongoing treatment and remain in remission may reduce their chances of developing colon cancer.   People with ulcerative colitis should talk with their health care provider about how often they should get screened for colon cancer. Screening can include colonoscopy with biopsies or a special dye spray called chromoendoscopy.   Health care providers may recommend colonoscopy every 1 to 3 years for people with ulcerative colitis who have   - the disease in one-third or more or of their colon   - had ulcerative colitis for 8 years    Such screening does not reduce a person's chances of developing colon cancer. Instead, screening can help diagnose cancer early and improve chances for recovery.   Surgery to remove the entire colon eliminates the risk of colon cancer.
Question: What are the symptoms of Peripheral Arterial Disease (P.A.D.) ?

Answer: Common Symptoms Some people with P.A.D. do not have any symptoms. Others may have a number of signs and symptoms. People who have P.A.D. may notice symptoms when walking or climbing stairs. These symptoms may include pain, aching, or heaviness in the leg muscles. Symptoms may also include - pain  - aching, or heaviness in the leg muscles  - cramping in the affected leg(s) and in the buttocks, thighs, calves, and feet. pain aching, or heaviness in the leg muscles cramping in the affected leg(s) and in the buttocks, thighs, calves, and feet. They may go away after resting. These symptoms are called intermittent claudication (klaw-dih-KA-shen). If You Have Leg Pain If you have leg pain when you walk or climb stairs, talk to your doctor. Sometimes older people think that leg pain is part of aging when it could be P.A.D. Tell your doctor if you're feeling pain in your legs, and discuss whether you should be tested for P.A.D. Other Possible Signs Possible signs of P.A.D. include - weak or absent pulses in the legs or feet  - sores or wounds on the toes, feet, or legs that heal slowly, poorly, or not at all  - a pale or bluish color to the skin  - a lower temperature in one leg compared to the other leg  - poor toenail growth and decreased leg hair growth  - erectile dysfunction, especially in men who have diabetes. weak or absent pulses in the legs or feet sores or wounds on the toes, feet, or legs that heal slowly, poorly, or not at all a pale or bluish color to the skin a lower temperature in one leg compared to the other leg poor toenail growth and decreased leg hair growth erectile dysfunction, especially in men who have diabetes. Should I be Checked for P.A.D.? Even if you don't have symptoms or signs of P.A.D., you could still have the disease. Ask your doctor whether you should get checked for P.A.D. if you are - age 70 or older  - age 50 or older and have a history of smoking or diabetes   - younger than 50 years old and have diabetes and one or more risk factors for atherosclerosis. These risk factors include high cholesterol levels, high blood pressure, smoking, and being overweight. age 70 or older age 50 or older and have a history of smoking or diabetes younger than 50 years old and have diabetes and one or more risk factors for atherosclerosis. These risk factors include high cholesterol levels, high blood pressure, smoking, and being overweight.