MAST2
Microtubule-associated serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the "MAST2" gene. The protein encoded by this gene controls TRAF6 and NF-kappaB activity. Interactions. MAST2 has been shown to interact with PCLKC. Model organisms. Model organisms have been used in the study of MAST2 function. A conditional knockout mouse line called "Mast2" has been generated. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping