Jean-Claude Weill
Jean-Claude Weill (born 14 August 1941), is a French biologist, immunologist and member of the French Academy of Sciences. Personal. Jean-Claude Weill is the son of Jean-Paul Weill, a lawyer at the Paris Court of Appeal, an officer of the Legion of Honour and holder of a war cross (1940–1945), and Denise Maier. He is the brother of Guy Weill, who died accidentally on 6 May 1966. Weill was married to Claudia Duxbury with whom he has a daughter Samantha Weill-Philippe (a psychoanalyst), and he subsequently married the lawyer, Frederique Pons. Career. Positions . Since 2014, Weill has been the Scientific co-director of the "Development of the immune system" team. Institut Necker-Enfants Malades Inserm U1151-CNRS in Paris. From 2001 to 2013, Weill was Scientific Co-Directorate of Inserm U783 "Development of the immune system" in the Faculty of Medicine Paris Descartes. Positions previous to that include:         Works. Weill's entire career has been spent in collaboration with Claude-Agnès Reynaud, who she met in Klaus Sherrer's laboratory at the Institut Jacques Monod, he is interested in the mechanisms of formation of the immunoglobulin repertoire, highlighting new mechanisms such as gene  conversion in birds, or the use of the somatic hypermutation process in ruminants in the formation of the preimmune repertoire. These strategies are accompanied by localized lymphocyte differentiation mainly in lymphoid tissues associated with the intestine. Their more recent work has focused on the molecular mechanisms of the hypermutation process of immunoglobulin genes, by describing the role played by mutagenic DNA polymerases in this process, as well as the mechanisms of immune memory formation, and the description of lymphocyte subpopulations in humans with similarities in their formation mode to that of B cells described in birds or ruminants. Jean-Claude  Weill is the author of a large number of scientific articles.