Cells at Work!
An anime television series adaptation by David Production premiered on July 8, 2018, with two seasons and 21 half-hour episodes aired as of February 27, 2021. A theatrical anime titled ""Hataraku Saibō!!" Saikyō no Teki, Futatabi. Karada no Naka wa "Chō" Ōsawagi!" premiered in September 2020. The anime adaptation of its spin-off series, "Cells at Work! Code Black", premiered in January 2021. Plot. The story takes place inside the human body, where trillions of anthropomorphic cells each do their job to keep the body healthy. The series largely focuses on two such cells; a rookie  red blood cell, AE3803, who often gets lost during deliveries, and a relentless white blood cell, U-1146, who fights against any germs that invade the body. Media. Manga. "Cells at Work!" is written and illustrated by Akane Shimizu. It was serialized in Kodansha's "shōnen" manga magazine "Monthly Shōnen Sirius" from January 26, 2015, to January 26, 2021. Kodansha has collected the manga into five "tankōbon" volumes . Kodansha USA announced that it had licensed "Cells at Work!" in North America on March 21, 2016. The manga is also licensed in Taiwan by Tong Li Publishing. Kodansha USA also announced that  it has licensed "Cells at Work! Code Black". Kodansha USA has also licensed five other spin-offs "Cells at Work!: Bacteria!", "Cells at Work!: Platelets!" and "Cells at Work!: Baby!", "Cells at Work! Neo Bacteria", and "Cells at Work! White Brigade. Spin-offs. The manga received a spin-off in the May 2017 issue of "Nakayoshi" called "Cells at Work!: Bacteria!" (; "Bacteria at Work") by Haruyuki Yoshida, which follows the lives of good and bad bacteria in the intestines. On June 3, 2020, it was announced that "Cells at Work!: Bacteria!" would end on July 3, 2020. A sequel series , titled "Cells at Work! Neo Bacteria", began serialization on "Nakayoshi" and the "Palcy" manga app in February 2021. Another spin-off, titled "Cells NOT at Work!" (; "Cells That Don't Work") by Moe Sugimoto, about immature red blood cells (erythroblasts) that do not want to work, was launched in the September 2017 issue of "Monthly Shōnen Sirius". It published its final chapter on November 26, 2021. The manga received another spin-off titled , set in a "black" environment of a human body suffering an unhealthy lifestyle, that runs in "Weekly Morning" since June 7, 2018. It is written by Shigemitsu  Harada, with illustrations by Issei Hatsuyoshi and supervision by Shimizu. The manga received another spin-off titled "Cells at Work and Friends!" (; "Cells at Work! Friend"), which centers around a Killer T Cell who is normally strict with himself and others, but wants to have fun during his free time. He also wants to make friends but does not want to ruin his reputation. The series began running in "Bessatsu Friend" on January 12, 2019. It is written by Kanna Kurono, and illustrated by Mio Izumi. It concluded on April 13, 2021. Another spin-off series focusing on the platelet  characters, titled written by Kanna Kurono and illustrated by Mio Izumi, began serialization in the June issue of "Monthly Shōnen Sirius" that was released on May 25, 2019. It concluded on April 26, 2021. Another spin-off series focusing cells inside the body of a baby 40 weeks since conception and nearing delivery, with the cells knowing nothing, titled illustrated by Yasuhiro Fukuda, was launched in the 45th issue of "Weekly Morning" on October 17, 2019. It concluded on October 7, 2021. Another spin-off series focusing on cells in the body of an adult woman, titled written by Harada  and illustrated by Akari Otokawa, was launched in the March issue of "Monthly Morning Two" on January 22, 2020. Another spin-off series focusing on white blood cells, titled illustrated by Tetsuji Kanie, was launched in the December issue of "Monthly Shōnen Sirius", which was released in October 2020. Another spin-off series, titled "Cells at Work!: Illegal" written and illustrated by Kae Hashimoto, began serialization in Kodansha's Young Magazine Web digital manga platform on February 1, 2022. Anime. An anime television series adaptation was announced in January 2018. It is directed by Kenichi Suzuki and animated by David  Production, with scripts written by Suzuki and Yūko Kakihara, and character designs by Takahiko Yoshida. The series' music is composed by Kenichiro Suehiro and MAYUKO. The anime series premiered on July 8, 2018, on Tokyo MX and other channels. The series ran for 13 episodes. Aniplex of America licensed the series in North America and simulcast it on Crunchyroll. Madman Entertainment simulcasted Australia and New Zealand on AnimeLab, while Muse Communication licensed the series in Southeast Asia and South Asia, and simulcasted it on Animax Asia. MVM Entertainment acquired the series for distribution in the United Kingdom and Ireland. The  opening theme is by Kana Hanazawa, Tomoaki Maeno, Daisuke Ono, and Kikuko Inoue in Japanese and Cherami Leigh, Billy Kametz, Robbie Daymond and Laura Post in English, while the ending theme is "CheerS" by ClariS. A special episode premiered on December 27, 2018. Aniplex of America released the English dub on August 27, 2019. On March 23, 2019, the official Twitter account announced that the series will receive a second season. The second season aired from January 9 to February 27, 2021. The main staff at David Production is returning for producing the second season, with the exception of director  Kenichi Suzuki being replaced by director Hirofumi Ogura. The opening theme is "Go! Go! Saibō Festa!" by the main cast members, while the ending theme is "Fight!!" by ClariS. A theatrical anime titled ""Hataraku Saibō!!" Saikyō no Teki, Futatabi. Karada no Naka wa "Chō" Ōsawagi!" was announced on July 4, 2020, as an advanced screening of episodes 4–8 later aired in the second season. Also shown with a short animation "Kesshouban: Eigakan e Iku". The main staff at David Production returned for producing the film, with the exception of director Kenichi Suzuki being replaced by director Hirofumi Ogura. It premiered  on September 5, 2020. Light novel. A light novel adaptation of the manga titled as was published on July 12, 2018, by Kodansha. It is written by Yui Tokiumi and illustrated by Akane Shimizu. Stage play. A stage play adaptation titled was announced in the August issue of Kodansha's "Monthly Shōnen Sirius" magazine. The play was held at Tokyo's Theatre 1010 from November 16 to 25, 2018. The play which was directed by Tsuyoshi Kida, starred Masanari Wada as U-1146 and Kanon Nanaki as AE3803, while Keita Kawajiri wrote the script for the play. The last performance, which  was held on the 25th, was also distributed live. Mobile app. A tower-defense game for iOS and Android mobile devices titled has been announced and is accepting pre-registration for players. The game service shut down at January 31, 2020. Reception. Rebecca Silverman of Anime News Network highlighted the educational aspect of the manga despite flaws in presentation of information, and ultimately found the manga entertaining with likable characters. Sean Gaffney of Manga Bookshelf called it a "very fun shonen action manga", complimenting the manga's ridiculousness and humor. Ian Wolf of Anime UK News gave the British Blu -ray release of the anime a score of 9 out of 10, and described the show as the most bloody on television, because so many of the characters are blood cells and thus means it contains more blood than shows depicting much violence. The 2016 "Kono Manga ga Sugoi!" guidebook listed the manga as the seventh top manga for male readers. Paul Gravett included the manga in his list of "Top 22 Comics, Graphic Novels & Manga" for October 2016. , the manga had over 1.3 million copies in print. The manga had over 1.5 million copies in print, . Dr. Satoru Otsuka , postdoctoral fellow in the molecular neuro-oncology department of Emory University School of Medicine in Atlanta, Georgia, praised the series' depiction of cancer cells during the series' seventh episode. Biology teachers at a high school affiliated with China's Southwest University were so impressed with the accuracy of the series that they assigned it as homework for their students.