Fadogia
Fadogia is a genus of flowering plants in the family Rubiaceae. The genera "Rytigynia" and "Fadogia" form a strongly supported clade but neither of these genera is monophyletic. Distribution. "Fadogia" is found in Tropical Africa. "F. cienkowskii" and "F. tetraquetra" have the largest distribution and occur from Guinea to the Transvaal province. "F. ancylantha" and "F. erythrophloea" are also found in many African countries, but they don't occur so far south. The countries with the highest number of species are Angola, Democratic Republic of the Congo, Zambia, Tanzania, and Central African Republic. Bacterial leaf symbiosis. Endophytic bacteria are  housed in the intercellular space of the leaf mesophyll tissue. The presence of these bacteria can only be microscopically ascertained. The bacteria are identified as "Burkholderia", which is a genus that is also found in the leaves of other Rubiaceae species. The hypothesis is that these endophytic bacteria provide chemical protection against insect herbivory. Gousiekte. "Fadogia homblei" is known to cause gousiekte, a cardiotoxicosis of ruminants characterised by heart failure four to eight weeks after ingestion of certain rubiaceous plants.