2022 United States Senate election in Missouri
The 2022 United States Senate election in Missouri will be held on November 8, 2022, concurrently with elections for all other Class 3 U.S. Senators and elections for the U.S. House of Representatives, to select a member of the United States Senate to represent the state of Missouri. On March 8, 2021, incumbent Republican Senator Roy Blunt announced that he would not seek reelection to a third term in office.