cyclosporin a (csa) is an immunosuppressive agent involved in the group of calcineurin inhibitors which are commonly used in management of transplantation and autoimmune diseases . despite new treatment strategies, it is still a widely used medication. however, numerous side effects restrict its usage in clinical practice; such as nephrotoxicity, neurotoxicity, hepatotoxicity, hypertension, dyslipidemia etc. cyclosporin a might give rise to acute or chronic nephrotoxicity [1--9]. acute form results from renal hemodynamic changes and is generally a reversible condition . however, in setting of chronic, all compartments of the kidney manifest histological alterations which are permanent. cyclosporin a induced chronic inflammation, oxidative stress and apoptosis result in progression of the damage and eventually chronic renal failure develops [3,4,6--12]. Clean regularly to prevent	BuySave	Consigned Refinished 1953 Cast Iron Double Drainboard Farm Sink 5 ft$2,027.65 · Only 1 Left professionally refinished by re in Crowley LA to achieve a porcelain-like smooth easy to clean surface. The sink is in nearly new condition refinished to it’sRefinished 1953 Cast Iron Double Drainboard Farm Sink 5 ft New Hardware