Ke eng sesosa sa kankere? Na ho na le pheko e tsebahalang bakeng sa eona kapa na mokhoa o mong oa phekolo o lokela ho fumanoa pele pheko ea eona e ka etsoa? Dihydromyricetin e fokotsa dysorubicin-ikiwa ea lefu la pelo ka ho thibela inflmasmome ea NLRP3 ka ts'ebetso ea SIRT1. Letsatsi Z, Lu W, Lin N, Lin H, Zhang J, Ni T, Meng L, Zhang C, Guo H. Biochem Pharmacol. 2020 Feb 26: 113888. Doi: 10.1016 / j.bcp.2020.113888. [Epub pele ho khatiso] E hlophisitsoeng liphetolelo tsa lihlahisoa tsena ho ile ha hahoa mmeedi ya lenaneo la ho matlafatsa bomasepala, eo lefa naheng ea systematization le tšepo ea ho nametse tšepo ea hore ho tla ba molemo bakeng sa ho linaheng tse ling. Ho isa tekanyong eo re etsa setjhaba boiteko bona, tsebo e democratized le ntlafala tshebedisano mora ithuta baahi hona joale li emela libaka online, makasine. Shutters on the Beach has been reinvented by President Barack Obama's White House interior designer, Michael Smith. Guest rooms and suites give the feeling of being in a private beach house. It's close to the beach, bedrooms have fireplaces and its reputation is that it's one of the best hotels around. Some people just don't like sand  and if that sounds like you there is a beautiful pool with huge deck so you can take a dip or unwind in the jacuzzi and look at the ocean while sipping a cocktail. Guests enjoy lunch and dinner and Sunday brunch in One Pico Restaurant. Its decor is soft blue and white and views across the boardwalk make for very pleasant dining. Coast, a beachside cafe and bar, serves breakfast, brunch, lunch and dinner and they have a happy hour every evening. Fred Segal began his legendary fashion empire in the late 1950s and it continues to thrive under the direction of his three children who say their dad was the father of fashion denim. The retail haven has the unusual in women's, men's and children's clothing, cosmetics and jewellery, shoes, accessories, cosmetics and gifts. Designers vie to be included in Fred's store and the likes of Jennifer Aniston, Meg Ryan, Britney Spears and Nicole Kidman are all customers. Catriona recommends you have plenty of time on hand when you visit as you won't want to leave in a hurry! Viceroy Santa Monica is another little gem. The owners have blended city chic with relaxed coast and offer 162 beautifully appointed rooms. It's restaurant Whist is highly acclaimed, and poolside Cameo Bar is a great place to enjoy a cocktail. Family