Nutmeg
Nutmeg is the seed or ground spice of several species of the genus "Myristica". "Myristica fragrans" (fragrant nutmeg or true nutmeg) is a dark-leaved evergreen tree cultivated for two spices derived from its fruit: nutmeg, from its seed, and mace, from the seed covering. It is also a commercial source of an essential oil and nutmeg butter. The California nutmeg, "Torreya californica", has a seed of similar appearance, but is not closely related to "Myristica fragrans", and is not used as a spice. Indonesia is the main producer of nutmeg and mace. If consumed in amounts exceeding its  typical use as a spice, nutmeg powder may produce allergic reactions, cause contact dermatitis, or have psychoactive effects. Although used in traditional medicine for treating various disorders, nutmeg has no scientifically confirmed medicinal value. Common nutmeg. Nutmeg is the spice made by grinding the seed of the fragrant nutmeg tree ("Myristica fragrans") into powder. The spice has a distinctive pungent fragrance and a warm, slightly sweet taste; it is used to flavor many kinds of baked goods, confections, puddings, potatoes, meats, sausages, sauces, vegetables, and such beverages as eggnog. The seeds are dried gradually in the sun over a period  of six to eight weeks. During this time the nutmeg shrinks away from its hard seed coat until the kernels rattle in their shells when shaken. The shell is then broken with a wooden club and the nutmegs are picked out. Dried nutmegs are grayish brown ovals with furrowed surfaces. The nutmegs are roughly egg-shaped, about long and wide, weighing dried. Two other species of genus "Myristica" with different flavors, "M. malabarica" and "M. argentea", are sometimes used to adulterate nutmeg as a spice. Mace. Mace is the spice made from the reddish seed covering (aril) of the nutmeg  seed. Its flavour is similar to nutmeg but more delicate; it is used to flavour baked goods, meat, fish, and vegetables, and in preserving and pickling. In the processing of mace, the crimson-colored aril is removed from the nutmeg seed that it envelops and is flattened out and dried for 10 to 14 days. Its color changes to pale yellow, orange, or tan. Whole dry mace consists of flat pieces—smooth, horn-like, and brittle—about long. Botany and cultivation. The most important commercial species is the common, true or fragrant nutmeg, "Myristica fragrans" (Myristicaceae), native to the Moluccas  (or Spice Islands) of Indonesia. It is also cultivated on Penang Island in Malaysia, in the Caribbean, especially in Grenada, and in Kerala, a state formerly known as Malabar in ancient writings as the hub of spice trading, in southern India. In the 17th-century work "Hortus Botanicus Malabaricus", Hendrik van Rheede records that Indians learned the usage of nutmeg from the Indonesians through ancient trade routes. Nutmeg trees are dioecious plants which are propagated sexually (seeds) and asexually (cuttings or grafting). Sexual propagation yields 50% male seedlings, which are unproductive. As there is no reliable method of determining plant  sex before flowering in the sixth to eighth year, and sexual reproduction bears inconsistent yields, grafting is the preferred method of propagation. Epicotyl grafting (a variation of cleft grafting using seedlings), approach grafting, and patch budding have proved successful, with epicotyl grafting being the most widely adopted standard. Air layering is an alternative though not preferred method because of its low (35–40%) success rate. The first harvest of nutmeg trees takes place seven to nine years after planting, and the trees reach full production after twenty years. Culinary uses. Spice. Nutmeg and mace have similar sensory qualities, with nutmeg having  a slightly sweeter and mace a more delicate flavour. Mace is often preferred in light dishes for the bright orange, saffron-like hue it imparts. Nutmeg is used for flavouring many dishes. Whole nutmeg can also be ground at home using a grater specifically designed for nutmeg or a multi-purpose grating tool. In Indonesian cuisine, nutmeg is used in dishes, such as spicy soups including variants of "soto", "konro", oxtail soup, "sup iga" (ribs soup), "bakso" and "sup kambing". It is also used in gravy for meat dishes, such as "semur" beef stew, ribs with tomato, and European derived  dishes such as "bistik" (beef steak), "rolade" (minced meat roll) and "bistik lidah" (beef tongue steak). In Indian cuisine, nutmeg is used in many sweet, as well as savoury, dishes. In Kerala Malabar region, grated nutmeg is used in meat preparations and also sparingly added to desserts for the flavour. It may also be used in small quantities in "garam masala". Ground nutmeg is also smoked in India. In traditional European cuisine, nutmeg and mace are used especially in potato and spinach dishes and in processed meat products; they are also used in soups, sauces, and baked goods. It is  also commonly used in rice pudding. In Dutch cuisine, nutmeg is added to vegetables such as Brussels sprouts, cauliflower, and string beans. Nutmeg is a traditional ingredient in mulled cider, mulled wine, junket and eggnog. In Scotland, mace and nutmeg are usually both ingredients in haggis. In Italian cuisine, nutmeg is used as part of the stuffing for many regional meat-filled dumplings like tortellini, as well as for the traditional meatloaf. Nutmeg is a common spice for pumpkin pie and in recipes for other winter squashes, such as baked acorn squash. In the Caribbean, nutmeg is often used in  drinks, such as the Bushwacker, Painkiller, and Barbados rum punch. Typically, it is a sprinkle on top of the drink. Fruit. The pericarp (fruit covering) is used to make jam, or is finely sliced, cooked with sugar, and crystallised to make a fragrant candy. Sliced nutmeg fruit flesh is made as "manisan" (sweets), either wet, which is seasoned in sugary syrup liquid, or dry coated with sugar, a dessert called "manisan pala" in Indonesia. In Penang cuisine, dried, shredded nutmeg rind with sugar coating is used as toppings on the uniquely Penang "ais kacang". Nutmeg rind is also blended (creating  a fresh, green, tangy taste and white colour juice) or boiled (resulting in a much sweeter and brown juice) to make iced nutmeg juice. In Kerala Malabar region of India, it is used for juice, pickles and chutney. Essential oil. The essential oil obtained by steam distillation of ground nutmeg is used in the perfumery and pharmaceutical industries. The volatile fraction contains dozens of terpenes and phenylpropanoids, including -pinene, limonene, -borneol, -terpineol, geraniol, safrol, and myristicin. In its pure form, myristicin is a toxin, and consumption of excessive amounts of nutmeg can result in myristicin poisoning. The oil is colorless  or light yellow, and smells and tastes of nutmeg. It is used as a natural food flavoring in baked goods, syrups, beverages, and sweets. It is used to replace ground nutmeg, as it leaves no particles in the food. The essential oil is also used in the manufacturing of toothpaste and cough syrups. Nutmeg butter. Nutmeg butter is obtained from the nut by expression. It is semisolid, reddish-brown in colour, and has the taste and smell of nutmeg itself. About 75% (by weight) of nutmeg butter is trimyristin, which can be turned into myristic acid, a 14-carbon fatty  acid, which can be used as a replacement for cocoa butter, can be mixed with other fats like cottonseed oil or palm oil, and has applications as an industrial lubricant. History. The earliest evidence of nutmeg usage comes in the form of 3,500 year old potsherd residues from the island of Pulau Ai, one of the Banda Islands in eastern Indonesia. The Banda Islands consist of eleven small volcanic islands, and are part of the larger Maluku Islands group. These islands were the only source of nutmeg and mace production until the mid-19th century. In the 6th century AD, nutmeg  spread to India, then further west to Constantinople. By the 13th century, Arab traders had pinpointed the origin of nutmeg to the Indonesian islands, but kept this location a secret from European traders. Colonial era. The Banda Islands became the scene of the earliest European ventures in Asia, in order to get a grip on the spice trade. In August 1511, Afonso de Albuquerque conquered Malacca, which at the time was the hub of Asian trade, on behalf of the king of Portugal. In November of the same year, after having secured Malacca and learning of Banda's location, Albuquerque  sent an expedition of three ships led by his friend António de Abreu to find it. Malay pilots, either recruited or forcibly conscripted, guided them via Java, the Lesser Sundas, and Ambon to the Banda Islands, arriving in early 1512. The first Europeans to reach the Banda Islands, the expedition remained for about a month, buying and filling their ships with Banda's nutmeg and mace, and with cloves in which Banda had a thriving "entrepôt" trade. An early account of Banda is in "Suma Oriental", a book written by the Portuguese apothecary Tomé Pires, based in Malacca from 1512  to 1515. Full control of this trade by the Portuguese was not possible, and they remained participants without a foothold in the islands. In order to obtain a monopoly on the production and trade of nutmeg, the Dutch East India Company (VOC) waged a bloody battle with the Bandanese in 1621. Historian Willard Hanna estimated that before this struggle the islands were populated by approximately 15,000 people, and only 1,000 were left (the Bandanese were killed, starved while fleeing, exiled or sold as slaves). The Company constructed a comprehensive nutmeg plantation system on the islands during the 17th century. As  a result of the Dutch interregnum during the Napoleonic Wars, the British invaded and temporarily took control of the Banda Islands from the Dutch and transplanted nutmeg trees, complete with soil, to Sri Lanka, Penang, Bencoolen, and Singapore. From these locations they were transplanted to their other colonial holdings elsewhere, notably Zanzibar and Grenada. The national flag of Grenada, adopted in 1974, shows a stylised split-open nutmeg fruit. The Dutch retained control of the Spice Islands until World War II. It has been suggested that Connecticut received its nickname ("the Nutmeg State", "Nutmegger") from the claim that some unscrupulous  Connecticut traders would whittle "nutmeg" out of wood, creating a "wooden nutmeg", a term which later came to mean any type of fraud. This narrative may have to do with the issue that one has to grate to obtain the spice powder, not crack a nutmeg, and this may not have been widely known by some purchasers of the product. Production. In 2019, global production of nutmeg was 142,000 tonnes, led by Indonesia, Guatemala, and India, having 38,000 to 43,000 tonnes each and a combined 85% of the world total. Psychoactivity and toxicity. Although used as a folk treatment for  other ailments, nutmeg has no proven medicinal value. Effects. Ingested in small amounts as a spice, nutmeg produces no noticeable physiological or neurological response, but in large doses, both raw nutmeg freshly ground from kernels and nutmeg oil have psychoactive effects, which appear to derive from anticholinergic-like hallucinogenic mechanisms attributed to myristicin and elemicin. Myristicin—a monoamine oxidase inhibitor and psychoactive substance—can cause convulsions, palpitations, nausea, eventual dehydration, and generalized body pain when consumed in large amounts. Nutmeg usage may increase endocannabinoids like anandamide and 2-AG levels or delay their breakdown by inhibiting FAAH and MAGL. Nutmeg  may interact with anxiolytic drugs, produce allergic reactions, cause contact dermatitis, and evoke acute episodes of psychosis. Varying considerably from person to person, nutmeg intoxication may occur with side effects, such as delirium, anxiety, confusion, headaches, nausea, dizziness, dry mouth, eye irritation, and amnesia. Intoxication takes several hours to reach maximum effect, and effects may last for several days. Rarely, nutmeg overdose causes death, especially if the nutmeg is combined with other drugs. Incidents of fatal poisoning from nutmeg and myristicin individually are uncommon. Nutmeg poisonings occur by accidental consumption in children and by intentional recreational use. Relatively large doses  of nutmeg are required to produce effects, therefore a majority of reported nutmeg intoxication cases appear to be the result of recreational use. It is used recreationally with the intention of achieving a low-cost high resembling psychedelics, particularly by adolescents, drug users, college students, and prisoners. Toxicity during pregnancy. Nutmeg was once considered an abortifacient, but may be safe during pregnancy if used only in flavoring amounts. If consumed in large amounts, nutmeg could cause premature labor and miscarriage. Nutmeg may also interact with pain-relievers such as pethidine, so it is recommended that it be avoided during pregnancy . Toxicity to pets. The scent of nutmeg may attract pets, but it can be poisonous to them if they consume too much.