Free fatty acid receptor 3
Free fatty acid receptor 3 (FFA3) is a G-protein coupled receptor that in humans is encoded by the "FFAR3" gene. Animal studies. Knockout mouse studies have implicated FFAR3 in diabetes, colitis, hypertension and asthma. However, discrepancies between the pathways activated by FFAR3 agonists in human cells and the equivalent murine counterparts have been observed. Heteromerization. FFAR3 may interact with FFAR2 to form a FFAR2-FFAR3 receptor heteromer with signalling that is distinct from the parent homomers.