Deuterated DMSO
Deuterated DMSO, also known as dimethyl sulfoxide-d, is an isotopologue of dimethyl sulfoxide (DMSO, (CH)S=O)) with chemical formula ((CD)S=O) in which the hydrogen atoms ("H") are replaced with their isotope deuterium ("D"). Deuterated DMSO is a common solvent used in NMR spectroscopy. Production. Deuterated DMSO is produced by heating DMSO in heavy water (DO) with a basic catalyst such as calcium oxide. The reaction does not give complete conversion to the d product, and the water produced must be removed and replaced with DO several times to drive the equilibrium to the fully  deuterated product. Use in NMR spectroscopy. Pure deuterated DMSO shows no peaks in H NMR spectroscopy and as a result is commonly used as an NMR solvent. However commercially available samples are not 100% pure and a residual DMSO-d H NMR signal is observed at 2.50ppm (quintet, J=1.9Hz). The C chemical shift of DMSO-d is 39.52ppm (septet).