ukubheja usuertia wazalelwa khona 2012, yize ngaphambili yayaziwa njengenkampani ezinikele kwi--paris yebhola lezinyawo online. u--eduardo losilla woza ngokuhamba kwesikhathi, tal vez el más conocido y..." The rats were randomly allocated into five groups, included six rats in each group. Pharmaceutical forms of each drug were administrated to animals by subcutaneous route for 21 days. 2 ml of saline was administered to group 1; 25 mg/kg/day CsA was administered to group 2; 25 mg/kg/day CsA and 4 mg/kg/day carvedilol were administered to group 3; 25 mg/kg/day CsA and 10 mg/kg/day atorvastatin were administered to group 4; 25 mg/kg/day CsA, 4 mg/kg/day carvedilol and 10 mg/kg/day atorvastatin were administered to group 5. On day 22, all animals were anesthetized with 40 mg/kg intraperitoneal ketamine hydrochloride (Ketalar Flakon, 45 mg/kg, Pfizer, Istanbul, Turkey) and blood samples were obtained by intracardiac way for determination of renal functions. The subjects were sacrificed after the kidneys had been removed. Left kidney was stored at -80°C for enzymatic analysis and the right kidney was placed into 10% formalin solution for histopathological evaluation.