Mel languages. With that being said, beta cells experience apoptosis early and thus are destroyed within a normal-functioning pancreas. The source of this seems to come from the transfer of Pander, a gene that works by attaching to RNA. Pander, when active, causes the beta cells to be blocked at S phase, which induces apoptosis. This loss of beta cell mass eventually leads to a loss of most of the transplanted beta cells. Heart valve. Biological valves are valves of animals, like pigs, which undergo several chemical procedures in order to make them suitable for implantation in the human heart. The 	Transplantable organs and tissues
9928106	porcine (or pig) heart is most similar to the human heart, and therefore represents the best anatomical fit for replacement. Implantation of a porcine valve is a type of Xenotransplantation, or Xenograft, which means a transplant from one species (in this case a pig) to another. There are some risks associated with a Xenograft such as the human body's tendency to reject foreign material. Medication can be used to retard this effect, but is not always successful. Ovary. Ovary transplantation, giving rise to successful pregnancies, will result in children who will have the genetic inheritance of the organ donor 	Transplantable organs and tissues
9928107	and not the recipient; it has so far only been carried out on identical twins. Use of an ovarian transplant from a genetically identical donor prevents rejection of the donated organ. This bypasses the need for immune suppressants to maintain the function of the donated ovary, which is not vital for survival. More significantly, many immunosuppressants, such as mycophenolate mofetil, may cause birth defects. A transgender woman Lili Elbe received an ovary transplant in the early 1930s, followed by a uterus transplant, but died shortly thereafter from complications. Transplantable organs and tissues Transplantable organs and tissues may both refer to 	Transplantable organs and tissues
9928108	Mel languages Mel languages The Mel languages are a branch of Niger–Congo languages spoken in Guinea-Bissau, Guinea, Sierra Leone, and Liberia. The most populous is Temne, with about two million speakers; Kissi is next, with half a million. Languages. Mel has traditionally been classified as the bulk of a southern branch of a West Atlantic branch of Niger–Congo. However, these are geographic and typological rather than genealogical groups; Segerer (2010) shows that there is no exclusive relationship between Mel and the other southern languages, Sua (Mansoanka), Gola and Limba. Fields (2004) splits Mel into a Highlands" group originating in  Guinea, and also a "Bullom-Kisi-Gola" group. Fields (2008:83) proposes that the homeland of Proto-Mel is located in the north-central highlands of Sierra Leone just to the south of the Lesser Scarcies River, rather than on the coast. The homeland of Proto-Highlands is located along the middle stretches of the Konkoure River in Guinea, just to the northeast of Conakry (Fields 2008:85). Comparative vocabulary. Comparison of basic vocabulary words in the Mel languages from Fields (2004): Comparison of basic vocabulary words in the Mel languages, and also Sua and Gola, from Wilson (2007): Limba has also  been added from Clarke (1922). Mel languages The Mel languages are a branch of Niger–Congo languages spoken in Guinea-Bissau, Guinea, Sierra Leone, and Liberia. The most populous is Temne, with about two million speakers; Kissi is next, with half a million. Languages. Mel has traditionally been classified as the bulk of a southern branch of a West Atlantic branch of Niger–Congo. However, these are geographic and typological rather than genealogical groups; Segerer (2010) shows that there is no exclusive relationship between Mel and the other southern languages, Sua (Mansoanka), Gola and Limba. Fields (2004) splits Mel into