Alpha-5 beta-1
αβ, also known as the fibronectin receptor, is an integrin that binds to matrix macromolecules and proteinases and thereby stimulates angiogenesis. It is composed of α (ITGA5/CD49e) and β (ITGB1/CD29) subunits. It is the primary receptor for fibronectin. The interaction of VLA-5 with fibronectin plays an important role in regulating inflammatory cytokine production by human articular chondrocytes (From the Cell Migration Gateway ITGA5 ITGB1). αβ-integrin is transported inside the cell by the kinesin KIF1C, a kinesin-3 organelle transporter that walks along microtubules.