2,3-Dichlorophenylpiperazine
2,3-Dichlorophenylpiperazine (2,3-DCPP or DCPP) is a chemical compound from the phenylpiperazine family. It is both a precursor in the synthesis of aripiprazole and one of its metabolites. It is unclear whether 2,3-DCPP is pharmacologically active as a serotonin receptor agonist similar to its close analogue 3-chlorophenylpiperazine ("m"CPP), though it has been shown to act as a partial agonist of the dopamine D and D receptors. Legality. 2,3-DCPP has been made illegal in Japan and Hungary after having been identified in seized designer drug samples. Positional Isomer. The positional isomer 3,4-dichlorophenylpiperazine (3,4-DCPP ) is also known, and acts as both a serotonin releaser via the serotonin transporter, and a β-adrenergic receptor blocker, though with relatively low affinity at both targets. Triple Substituted. The 3,4,5-Trichlorophenylpiperazine [67305-64-0] ("3 stripes") is also a highly regarded arrangement & has been awarded the Beecham patent of . Such 3,4,5-Trisunstituted aromatic entities is already known from clenbuterol. Leading to CID:151687078 (Ex 6 is a concrete example of this) i.e. 1-(4-Amino-3,5-dichlorophenyl)-4-(4-phthalimido-1- butyl)piperazine.