Streptomyces albidoflavus
Streptomyces albidoflavus is a bacterium species from the genus of "Streptomyces" which has been isolated from soil from Poland. "Streptomyces albidoflavus" produces dibutyl phthalate and streptothricins. Small noncoding RNA. Bacterial small RNAs are involved in post-transcriptional regulation. Using deep sequencing "S. albidoflavus" transcriptome was analysed at the end of exponential growth. 63 small RNAs were identified. Expression of 11 of them was confirmed by Northern blot. The sRNAs were shown to be only present in "Streptomyces" species. sRNA scr4677 ("Streptomyces coelicolor" sRNA 4677) is located in the intergenic region between anti-sigma factor "SCO4677" gene and a  putative regulatory protein gene "SCO4676". "scr4677" expression requires the "SCO4677" activity and "scr4677" sRNA itself seem to affect the levels of the "SCO4676"-associated transcripts. Targets of two of "S. albidoflavus" noncoding RNAs have been identified. Noncoding RNA of Glutamine Synthetase I was shown to modulate antibiotic production. The small RNA scr5239 ("Streptomyces coelicolor" sRNA upstream of SCO5239) has two targets. It inhibits agarase DagA expression by direct base pairing to the dagA coding region, and it represses translation of methionine synthase "metE" (SCO0985) at the 5' end of its open reading frame. Fatty acid synthesis. A crystal structure is available  of the "S. albidoflavus" "S"-malonyltransferase. "S. albidoflavus"s ACP "S"-MT is involved in both fatty acid synthesis II and polyketide synthase and is structurally similar to "Escherichia coli"s analogue. Usage in biotechnology. Strains of "S. albidoflavus" produce various antibiotics, including actinorhodin, methylenomycin, undecylprodigiosin, and perimycin. Certain strains of "S. albidoflavus" can be used for heterologous protein expression. DNA repair. The Ku homolog is SCF55.25c. It contains an Shrimp alkaline phosphatase-like (SAP-like) domain at the C-terminus. "S. albidoflavus" produces a (putatively) single-domain protein SC9H11.09c which is homologous to the LigD NucDom which is common to many bacterial LigDs . (LigDs are a subfamily of DNA ligases. In bacteria many, but not all LigDs have additional nuclease domains branched from the universally present central ligase domain. If present - as in this case - the nuclease domain is an N-terminus extension.) Genetics. The genome consists of a single linear molecule, and although Ku would be expected to perform end maintenance, none has been observed so far.