1927 U.S. National Championships – Women's singles
First-seeded Helen Wills defeated Betty Nuthall 6–1, 6–4 in the final to win the women's singles tennis title at the 1927 U.S. National Championships. The event was held at the West Side Tennis Club, Forest Hills, New York City. It was Wills's fourth U.S. National singles title. She won the title without losing a set and lost only 18 games in six matches.