Peter Zandstra
Peter W. Zandstra, is a Canadian scientist who is the I’Anson Professor of Tissue Engineering and a Canada Research Chair in Stem Cell Bioengineering at the University of Toronto Institute of Biomedical Engineering. Education. Zandstra graduated with a Bachelor of Engineering degree from McGill University in the Department of Chemical Engineering and later obtained his Ph.D. degree from the University of British Columbia in the Department of Chemical Engineering and Biotechnology, under the supervision of Jamie Piret and Connie Eaves. He continued his research training as a Post Doctoral Fellow in the field of Bioengineering at the Massachusetts  Institute of Technology (with Doug Lauffenburger) before being appointed to the University of Toronto in 1999. Career. Since 2016 Zandstra holds an academic appointment as a Professor at the University of Toronto's Institute of Biomaterials and Biomedical Engineering. He is cross appointed with the Departments of Chemical Engineering and Applied Chemistry and Medical Genetics. As of July 2017, Zandstra additionally serves as a Founding Director of the School of Biomedical Engineering at the University of British Columbia and is a Director of the Michael Smith Laboratories. At the University of British Columbia he also holds a post of Principal  Investigator. Zandstra also serves on the advisory board of the Phil and Penny Knight Campus for Accelerating Scientific Impact of the University of Oregon and serves as Chief Scientist at the Creative Destruction Lab. He also is a Chief Scientific Officer at the Centre for Commercialization of Regenerative Medicine and is a part of the Silver Creek Pharmaceuticals team. Research. Research in the Zandstra Laboratory is focused on the regeneration of functional tissues from stem cells, and the development and utilization of tools to modulate the responses of stem cells "in vitro" and "in vivo". Interest in the generation of  primary cells and tissues "ex vivo" is driven both by their potential use as a direct clinical modality and as human tissue analogues for the development of novel therapeutic agents. Zandstra's group is particularly interested in understanding the role that the extracellular environment, the stem cell niche, plays in controlling stem cell fate decisions. Using quantitative bioengineering approaches including micro-fabrication, bioreactors, mathematical modeling, and protein and cell engineering, the Zandstra Lab is discovering how stem cells integrate their complex microenvironment to make self-renewal or differentiation divisions. The group is focused on using this understanding to enable new  therapeutically and technologically relevant strategies in regenerative medicine. The Zandstra lab focuses in particular on understanding how to grow human blood stem cells, and on understanding how to differentiate pluripotent stem cells into functional blood, cardiac, and pancreatic tissue. Zandstra currently serves as associate editor for the journals "Stem Cells", "Stem Cell Research" and "Biotechnology and Bioengineering". In addition to his research, Zandstra teaches in Cellular Engineering, having developed both undergraduate and graduate curricula covering the use of mathematical models to describe and predict cell fate decisions. Zandstra helped with the founding of the IBBME teaching laboratory, designing and implementing  more than 6 labs. He currently serves as the Director of the University of Toronto's Minor in Bioengineering, an engineering faculty-wide program designed to give undergraduate students a co-ordained series of courses in bioengineering related topics. Awards and honours. In 2008, during an annual conference held by the American Association for the Advancement of Science, Zandstra was inducted as its Fellow. In 2014 Zandstra was elected as a Fellow of the Royal Society of Canada and a year later he was recognized for contributions to development and commercialization of stem cell-based therapies and became a recipient  of the Scale-Up and Manufacturing of Cell-Based Therapies Award. In 2017 Zandstra was appointed as Canada Research Chair in Stem Cell Bioengineering. His other recognitions include: