Visine
Visine is a brand of eye drops produced by Johnson & Johnson. Johnson & Johnson acquired Visine, along with Pfizer's entire consumer healthcare portfolio, in December 2006. In some countries it is called Vispring. Visine Original. The active ingredients in the original Visine formulation are potassium chloride and tetrahydrozoline hydrochloride which is a vasoconstrictor, and therefore constricts the eye's superficial blood vessels. Administration. Visine is administered topically with 1 to 2 drops applied to the affected eye(s) up to 4 times daily . Side effects. A common urban legend is that a few drops of Visine in an unsuspecting victim 's drink will cause harmless but debilitating bouts of explosive diarrhea, akin to that of a laxative. This will not produce explosive diarrhea, but oral administration of Visine can induce dangerous side effects related to Visine's ingredient tetrahydrozoline hydrochloride such as: Anyone ingesting Visine should get medical attention or contact a poison control center immediately. Ingesting Visine was shown to be lethal in the case of Lana Clayton, who killed her husband by administering Visine to his drinks over a period of three days in July 2018. Varieties. Visine is formulated in several varieties: VISINE A.C. - Astringent/Redness Reliever  Eye Drops (Tetrahydrozoline HCl 0.05%, Zinc sulfate 0.25%) VISINE FOR CONTACTS - For Silicone Hydrogel and Hydrophilic lenses VISINE L.R. (Oxymetazoline HCI 0.025%) VISINE TEARS (Glycerin 0.2%, Hypromellose 0.2%, Polyethylene glycol 400 1% - Used AS NEEDED) VISINE-A (Formerly OCUHIST) (Naphazoline/pheniramine) VISINE MAXIMUM (Glycerin 0.2%, Hypromellose 0.36%, Polyethylene glycol 400 1.0%, Tetrahydrozoline HCI 0.05%) VISINE TOTALITY (Glycerin 0.2%, Hypromellose 0.36%, Polyethylene glycol 400 1.0%, Tetrahydrozoline HCI 0.05%, Zinc sulfate 0.25%) Popular culture. The effect of Visine causing upset gastrointestinal effects when being ingested is depicted in the movie "Wedding Crashers," where John Beckwith (portrayed by Owen Wilson) poisons Sack's  (Bradley Cooper) drink, causing him to suffer all night. John Beckwith also uses the Visine several times over the course of the film to fake crying. This movie has gained notoriety for encouraging the deadly prank of putting Visine eyedrops in drinking water bottles, threatening severe or fatal injury to drinkers. The urban legend about Visine's explosive diarrhea-inducing capacity is also perpetuated in the movie version of "I Hope They Serve Beer in Hell". In the movie, the main character Tucker Max (played by Matt Czuchry), is making fun of two women at the bar, in which one  of them squirts Visine into his beer bottle. This leads to Tucker and an allegedly married woman he leaves the bar with to both have extreme explosive diarrhea. In season 4, episode 3 of "Orange Is the New Black", an inmate poisons a fellow inmate using Visine; the poisoned inmate immediately experiences explosive diarrhea.