Three positively charged residues on each S4 helix are paired at the resting membrane potential with negative charges on other transmembrane helices in a staircase geometry.
(Three positively charged residues on each S4 helix; are paired; at the resting membrane potential with negative charges on other transmembrane helices in a staircase geometry)
Three positively charged residues on each S4 helix
are paired
at the resting membrane potential with negative charges on other transmembrane helices in a staircase geometry