Assertion: telomere | /r/CapableOf | shorten a cell divides
Facets:
value: every time
type: TEMPORAL
value: due to incomplete lagging strand synthesis
type: CAUSE
value: in most somatic cells
type: LOCATION
Source sentences:
text: Telomeres shorten every time a cell divides, which happens automatically as we age.
text: The researchers repeatedly exposed cultured cancer cells to this targeted oxidation procedure, mimicking conditions of environmental oxidative stress and inflammation, and, indeed, they saw the telomeres break and shorten with each cell division, despite repair efforts by the telomere lengthening enzyme telomerase.
text: In most somatic cells, telomeres shorten with cell divisions, eventually leading to cellular senescence.
text: These structures prevent the eventual loss of coding DNA due to the end replication problem, a limitation that causes telomere shortening within each cell division and leading, eventually, to cellular senescence or apoptosis [ 1 ].
text: Telomeres shorten every time a cell divides; they shrink by half from infancy to adulthood, and again by half among the elderly.
text: Telomeres shorten with each cell division, due to incomplete lagging strand synthesis.