Assertion: telomere | /r/HasSubevent | crisis
Facets:
value: with stem cell regeneration
type: OTHER
Source sentences:
text: In the event that cell lineages circumvent the proliferative block imposed by senescence, the telomeres of these cells will continue to shorten, leading to crisis, in which chromosomal fusions, genetic instability, and widespread cell death occur.
text: DKC (dyskeratosis congenita) patients are all characterized by the defective maintenance of telomeres leading to problems with stem cell regeneration.