Assertion: thrombolytic therapy | /r/ObjectUse | used in the community setting
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text: The findings of this observational study regarding the use of thrombolytic agents in a large community population of AMI patients suggest that (1) in general, thrombolytic recipients have fewer comorbidities and risk factors than nonrecipients; (2) thrombolytic use is associated with reduced mortality among eligible patients younger than 80 years but increased mortality among the old-old; the oldest patients, even those without relative or absolute contraindications to therapy, experienced an excess risk of mortality compared with untreated patients (OR, 1.4 for thrombolytic recipients 80-90 years); and (3) the manner in which thrombolytic therapy is used in the community setting differs markedly from that observed in randomized clinical trials, where patients are selected for treatment using explicit and consistent criteria and agents are administered according to protocol.