Assertion: thalidomide | /r/CapableOf | suppress elevated tnf-α
Facets:
value: in the striatum
type: LOCATION
value: in substantia
type: LOCATION
Source sentences:
text: Finally, in a recent study, both 3,6′DT and thalidomide were demonstrated to mitigate the severity of L -dopa-induced dyskinesia in nigrostriatal-lesioned rat models of PD, suppressing both microgliosis and elevated TNF-α in the striatum and substantia nigra, and restoring IL-10 anti-inflammatory cytokine levels (Boi et al., 2019).