Assertion: steroid's effect | /r/HasProperty | common
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text: Beginning 1990s the concept of oral high-dose MP received intense attention, which in most trials was found to be comparable to the effects of IVMP.72,83,84 Financial, logistical, and other practical advantages associated with the oral route of administration are apparent.6 A double-blind, randomized, placebo-controlled study26 with 51 patients randomized to either the group of oral MP (500 mg once a day for 5 days followed by a tapering period) or the placebo group showed that there were significantly more responders in the oral MP group, concluding that oral high-dose MP is efficacious in managing attacks of MS, and although adverse effects were common, no serious side effects were observed.