Assertion: thalidomide | /r/CapableOf | reduce nf-κb activation
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text: Thalidomide and lenalidomide have also been shown to reduce microgliosis and NF-κB activation, motor deficits, and excitotoxicity and DA fiber loss in the striatum of PD mouse models (Palencia et al., 2015; Valera et al., 2015), supporting the potential use of IMiDs as a treatment for PD.