Assertion: warfarin | /r/RelatedTo | tissue necrosis
Facets:
value: following warfarin administration
type: TEMPORAL
Source sentences:
text: : COUMADIN reduces the synthesis of the naturally occurring anticoagulants, protein C and protein S. Hereditary or acquired deficiencies of protein C or its cofactor, protein S, have been associated with tissue necrosis following warfarin administration.
text: Deficiency in protein C-mediated anticoagulant response: Coumadin reduces the synthesis of the naturally occurring anticoagulants, protein C and protein S. Hereditary or acquired deficiencies of protein C or its cofactor, protein S, have been associated with tissue necrosis following warfarin administration.