Assertion: tryptophan | /r/HasProperty | tdo
Facets:
Source sentences:
text: Approximately 95% of the Trp ingested is degraded to kynurenine, kynurenic acid (KA), quinolinic acid, picolinic acid, and nicotinamide adenine dinucleotide (NAD) through KP, which is regulated by two rate-limited enzymes: tryptophan 2,3-dioxygenase (TDO) in the liver and indoleamine 2,3-dioxygenase
text: In mammals, the first and rate-limiting step of the kynurenine pathway can be executed by three enzymes: tryptophan 2,3-dioxygenase (TDO), indoleamine 2,3-dioxygenase (IDO) and indoleamine 2,3-dioxygenase-2 (IDO-2).
text: Tryptophan 2,3-dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO) constitute an important, yet relatively poorly understood, family of heme-containing enzymes.
text: Tryptophan 2,3-dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO) catalyze the oxidative cleavage of the l-tryptophan (l-Trp) pyrrole ring, the first and rate-limiting step in l-Trp catabolism through the kynurenine pathway (1–3).