Assertion: induced pluripotent stem cell | /r/HasProperty | ipscs
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text: Known as induced pluripotent stem cells (iPSCs), these engineered cells can be controlled to act in certain ways in lab cultures.
text: We refer to these 2i-competent, ESC-like, and GFP-positive cells as chemically induced pluripotent stem cells (CiPSCs).
text: In order to investigate the effects of the pH on cell culture, the methods to produce induced pluripotent stem cells (iPSC s) and to differentiate embryonic stem cells (ESC s) into mesendoderm and neuroectoderm were performed at each medium pH from 6.6 to 7.8.
text: Induced pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from a somatic cell.
text: These were termed induced pluripotent stem cells (iPSCs).
text: A proof-of-concept of using induced pluripotent stem cells (iPSCs) to generate human organ for transplantation was reported by researchers from Japan.
text: Yamanaka was the first to demonstrate (in 2006) that this somatic cell nuclear transfer or oocyte-based reprogramming process (see below), that Gurdon discovered, could be recapitulated (in mice) by defined factors (Oct4, Sox2, Klf4, and c-Myc) to generate induced pluripotent stem cells (iPSCs).
text: Upon succeeding with embryonic stem cells, the group was able to successfully promote the differentiation of induced pluripotent stem cells (iPSCs) into PGLCs.
text: This new type of stem cell is now known as induced pluripotent stem cells (iPSCs).
text: An approach to patient-specific pluripotent stem cell derivation that precludes the use of embryos is based on somatic cell reprogramming by induced expression of a few critical transcription factors (referred as induced pluripotent stem cells [iPSCs]) ().
text: Almost all factors that reprogram cells into pluripotency have been discovered and can turn a wide variety of cells back into induced pluripotent stem cells (iPSCs).
text: (F): Immunostaining demonstrating differentiation of induced pluripotent stem cells (iPSCs) into all three germ layers.
text: (A): The level of Mbd3 mRNA is decreased in induced pluripotent stem cells (iPSCs) and murine embryonic stem cells (mESCs).
text: In theory, patient-specific ES cells can be generated by inducing somatic cells to revert to an embryonic state either by genetic manipulation to produce so called induced pluripotent stem cells (iPSCs), or by performing somatic cell nuclear transfer (SCNT) to harness the reprogramming power of the oocyte (the female gamete).
text: Induced pluripotent stem cells (iPSCs) are already routinely used in different research applications.
text: The major applications of induced pluripotent stem cells (iPSCs) are twofold.
text: The recent development of induced pluripotent stem cells (iPSCs) and related technologies has caught the attention of scientists, activists, politicians, and ethicists alike.
text: The canonical Yamanaka reprogramming factors yield induced pluripotent stem cells (iPSCs) that in mouse are naive, but in human are primed ().
text: These artificially manipulated cells are called induced pluripotent stem cells (iPSCs) and they are now being studied for growing human organs such as pancreases and kidneys outside the body for surgical transplantation.
text: A microscopic view of a colony of induced pluripotent stem cells (iPSCs).
text: These cells, that are as effective as cells isolated from early embryos, are termed induced pluripotent stem cells (iPSCs).
text: Significance Statement This article focuses on research utilizing a specific pluripotent stem cell type, known as induced pluripotent stem cells (iPSCs), in wildlife conservation and animal welfare, summarizing past and future avenues, and discussing its benefits and limitations.
text: Introduction Reprogramming of adult somatic cells into induced pluripotent stem cells (iPSCs) has massive potential to revolutionize personalized medicine, drug discovery, and cell therapy, but this represents only a portion of iPSC technology's capabilities.
text: 2.1 Making ventral midbrain progenitor cells To make ventral midbrain cells, we began with a very pure population of induced pluripotent stem cells (iPSCs; Figure 1A and B), where iPSC colonies stained for pluripotency markers, had a normal karyotype, expressed endogenous Yamanaka factors, and could be differentiated into three germ layers.
text: From this point, fibroblasts are the most commonly used primary somatic cell type for the generation of induced pluripotent stem cells (iPSCs).
text: Since the initial description of Yamanaka and Takahashi in 2006, the generation of induced pluripotent stem cells (iPSCs) has become a widely used method .