Assertion: tyrosine | /r/CapableOf | regulate the accessibility of psgl-1
Facets:
value: via electrostatic interactions
type: MANNER
value: to l-selectin
type: TRANSITIVE-OBJECT
value: to p-
type: TRANSITIVE-OBJECT
Source sentences:
text: The affinity differences were attributed to major changes in the forward rate and minor changes in the reverse rate, suggesting that these tyrosines regulate the accessibility of PSGL-1 to P- and L-selectin via electrostatic interactions, which is supported by molecular-dynamics simulations.