Assertion: stem cell's state | /r/HasProperty | figure
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text: Poised enhancers and invariant CTCF sites display minor differences in connectivity across the three cellular states ( Figures 7 E and 7F), whereas ESC-specific CTCF sites lose their interactions upon differentiation and only partially gain back connectivity in iPSCs ( Figure 7 G).
text: We next employed a thresholding strategy to classify 3D interactions by their dynamic contact frequencies across the three cellular states ( Figures 3 A–3D).
text: Upon application of our classification scheme, we uncovered several dynamic interaction classes among ESC, NPC, and iPSC cellular states ( Figures 3 I and 3J), including: (1) 537 interactions present in ESCs, lost in NPCs, and reacquired upon reprogramming (purple class)