Assertion: stroma's rna | /r/HasProperty | lncrnas
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text: However, with progressive replications, a marked production of ROS occurs, inducing damage to cellular macromolecules, with the involvement of several cellular pathways including p53, forkhead box transcription factors of the class O (FOXO1), nuclear factor erythroid 2-related factor (2Nrf2), micro RNAs (miRNAs) and long non-coding RNAs (lncRNAs) (for a comprehensive review, see [ 65 ]).