Assertion: telomerase | /r/HasProperty | reverse transcriptase
Facets:
Source sentences:
text: Telomerase seems to be unique to mammalian cells in that it is a reverse transcriptase comprising an RNA component (hTR) that serves as the template for the addition of the repeated sequence to telomere ends.
text: Telomerase is a reverse transcriptase enzyme which has recently emerged as an aractive target
text: The telomerase in cells, Blackburn discovered, is also a reverse transcriptase enzyme – it assembles and adds telomeric DNA to the ends of chromosomes by copying a small part of its RNA into telomeric DNA.
text: Telomerase is a reverse transcriptase, which is encoded by the Tert (telomerase reverse transcriptase) gene, that specifically recognizes the 3′-OH group at the end of this overhang.
text: Telomerase is a reverse transcriptase holoenzyme3 requiring three minimal essential components for catalytic activity: a reverse transcriptase protein (TERT),21,22 a nontranscribed RNA template molecule (TERC also referred to as TR),23 and the H/ACA snRNP member dyskerin
text: Telomerase is a reverse transcriptase that synthesizes telomere sequences and is responsible for telomere elongation.
text: The key words used included: telomerase, telomeres, telomere length, telomerase reverse transcriptase (TERT), telomeric RNA component (TERC), shelterin proteins, telomerase associated proteins, with endometrium, endometriosis, endometrial hyperplasia, endometrial cancer (EC), endometrial carcinomas, uterine cancer, cancers.
text: EST2 was shown to be homologous to a ciliate telomerase component purified and identified by Joachim Lingner and Tom Cech, leading the three of them to show that EST2 encodes the catalytic protein component of telomerase—the telomerase reverse transcriptase (TERT)36.
text: Telomerase is a reverse transcriptase enzyme that regenerates the telomere DNA sequences that exist on the ends of eukaryotic chromosomes.
text: Telomerase is a reverse transcriptase enzyme that regenerates the telomere DNA sequences that exist on the ends of eukaryotic chromosomes.
text: Telomerase is a reverse transcriptase enzyme that carries its own RNA molecule (e.g., with the sequence 3′-CCCAAUCCC-5′ in Trypanosoma brucei) which is used as a template when it elongates telomeres.