Assertion: sympathetic nervous system's effect | /r/HasProperty | mediated by circulating
Facets:
Source sentences:
text: The effect of SNS activation on the periphery is mediated by 4 pathways (6): 1) norepinephrine (NE) releasing neurons through the right stellate ganglion reaching the sinus and atrioventricular nodes (resulting in an increase in heart rate and shortening of atrioventricular conduction) and through the left stellate ganglion reaching the left ventricle (resulting in an increase in contractile strength and blood pressure); 2) epinephrine (EPI), released in circulation by the adrenal cortex affecting both the myocardium and peripheral vessels; 3) direct effect on peripheral vessels through local release of EPI and NE; and 4) circulating NE, which can act in multiple locations (e.g., increase in heart rate during exercise of heart transplant recipients)