Assertion: tryptophan's effect | /r/HasProperty | mediated by oestrogen receptor
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text: 9–12]. Subsequent studies have further shown that the effect of oestrogen on TPH1 and TPH2 is mediated by oestrogen receptor 2 (ESR2, also known as ERβ), one of the nuclear oestrogen receptors that act as ligand-gated transcription factors [13–15].