Assertion: tryptophan's role | /r/HasProperty | suggested by altered ido2 splicing
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text: These experimental observations are difficult to reconcile with the proposed model of IDO2 functioning as an immunosuppressive enzyme, and suggest a more subtle immunoregulatory role for IDO2, also in line with its genetic epistatic interaction with IDO1, suggested by the altered IDO2 splicing observed in IDO1-knockout mice (69).