Assertion: cancer stem cell | /r/HasProperty | cscs
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text: Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample.
text: In accordance with the hierarchy model of tumours, the cancer stem cells (CSC) are maintained by biochemical and physical contextual signals emanating from the microenvironment, called the cancer stem cell niche.
text: The important step toward malignancy is the induction of epithelial mesenchymal transition (EMT) in the stationary cancer stem cells (SCS), which become mobile or migrating cancer stem cells.
text: For example, some cancers may originate from the transformants of normal stem cells or progenitor cells, so-called cancer stem cells (CSCs), whereas ageing is induced through a progressive functional decline in certain stem cells (McEachern et al, 2000).
text: Brain Tumor Stem Cells Multipotent neural stem-like cells, known as brain tumor stem cells (BTSCs) or cancer stem cells (CSCs), have been identified and isolated from different grades (low and high) and types of brain cancers, including gliomas and medulloblastomas.51-52
text: Interestingly, mitochondrial parameters observed in cancer stem cells (CSCs) including mitochondrial mass, mitochondrial morphology, mtDNA copy number, and oxygen consumption are similar to those observed in iPSCs, which may imply some common metabolic features between iPSCs and CSCs that may help in their further characterization and study ().
text: induced pluripotent stem cells (iPSCs), produced by the reprogramming of somatic cells; and cancer stem cells (CSCs).
text: This functional heterogeneity among cancer cells has led to the creation of multiple propagation models to account for heterogeneity and differences in tumor-regenerative capacity: the cancer stem cell (CSC) and stochastic model.
text: Within the cancer population of the tumors there are cancer stem cells (CSC) that are tumorigenic cells and are biologically distinct from other subpopulations
text: Cancer stem cells (CSC), or tumor-initiating cells, are postulated to be specialized cells within tumors which are responsible for propagating cancer growth (Al-Hajj and Clarke, 2004).
text: The important step toward malignancy is the induction of epithelial mesenchymal transition (EMT) in the stationary cancer stem cells (SCS), which become mobile or migrating cancer stem cells.