Assertion: thalidomide | /r/HasProperty | effective
Facets:
value: very
type: DEGREE
value: for myeloma
type: TRANSITIVE-OBJECT
value: in inducing clinical remission
type: TRANSITIVE-OBJECT
value: for some people with multiple myeloma
type: OTHER
value: in healing orogenital ulceration
type: OTHER
value: for treating people
type: PURPOSE
value: for the treatment of multiple myeloma
type: PURPOSE
value: in treating some covid-19 patients
type: OTHER
value: in suppressing tumor growth
type: TRANSITIVE-OBJECT
Source sentences:
text: Meanwhile, a member of his lab, Robert D'Amato, who was looking for angiogenesis inhibitors, discovered in 1994 that thalidomide inhibited angiogenesis and was effective in suppressing tumor growth in rabbits.
text: Two clinical trials at Wenzhou Medical University will soon be recruiting participants to establish whether thalidomide, in tandem with low-dose hormones, might be an effective treatment for the often lethal form of pneumonia peculiar to severe cases of COVID-19.
text: Researchers at Chemie Grünenthal found that thalidomide was a particularly effective antiemetic that had an inhibitory effect on morning sickness.
text: Please understand, I am very thankful for the drug and one of the many that are living proof that thalidomide is an effective short term treatment for Myeloma but that does not change the facts of the matter and that is: Celgene has been taking advantage of us by over charging.
text: While too late to help those whose lives were blighted by the drug during pregnancy, this finding could help rehabilitate thalidomide, which is effective against several serious conditions, including multiple myeloma, a form of cancer.
text: It has been reported that thalidomide as an immunomodulatory agent for the treatment of IRIS is effective.
text: Surprisingly, it was just a few years after the thalidomide disaster that the drug was found to be effective for the treatment of Erythema nodosum leprosum (ENL), a complication of leprosy, where painful and inflamed skin lesions occur on the face, arms and legs.
text: Thalidomide is also very effective for the treatment of multiple myeloma, a cancer of white blood cells.
text: Thalidomide is also effective in the treatment of Hereditary hemorrhagic telangiectasia (HHT) a condition where vessels form abnormally and cause bleeding into organs and from the skin and nose.
text: In 1964, an Israeli dermatologist, Jacob Sheskin, M.D., observed that thalidomide was effective in treating a particularly disfiguring form of leprosy called erythema nodosum leprosum (ENL), a disease known to cause diffuse red nodular lesions along with fever, weight loss, arthritis, and general malaise.  
text: Subsequent research has shown that thalidomide is effective in the treatment of multiple myeloma.
text: Thalidomide has also been approved for the treatment of some types of cancer and is particularly effective for multiple myeloma after attempts at standard therapies such as chemotherapy have proven unsuccessful.
text: Overall, the drug was effective in inducing clinical remission in 20-70% of patients (average of 40%).
text: Given the hypotheses that thalidomide will be effective in inducing clinical remission at 8 weeks in 60% of patients with Crohn's disease, and 55% of patients with ulcerative colitis, compared to 20% of patients with placebo, with a significance of 0.05% and a power of 80%, estimated needed sample size is of 124 patients.
text: Dermatology professor Andrew G. Franks Jr., MD, of the NYU Langone Medical Center, says thalidomide is very effective for treating people with lupus skin conditions who do not respond to standard treatments such as steroids and antimalarial drugs.
text: It will still be some time before researchers know whether thalidomide is effective in treating some COVID-19 patients.
text: So says a Mayo Clinic study, published in the April issue of Leukemia, which is the first to show that thalidomide may be effective for some people with multiple myeloma, an incurable bone marrow cancer.
text: For instance, thalidomide has been very effective in healing orogenital ulceration via its anti-inflammatory effects while simultaneously inducing or exacerbating erythema nodosum via its T-cell costimulatory effects in Behcet syndrome patients (Hamuryudan et al., 1998).