Assertion: stem cell's level | /r/HasProperty | high
Facets:
value: in npcs
type: LOCATION
Source sentences:
text: Ume6 recruits the histone deacetylases, Rpd3 and Sin3, to repress EMG expression when glucose and nitrogen levels are high, and it recruits the EMG transcription factor Ime1 when glucose and nitrogen levels are low.
text: When glucose levels in the surroundings are high, the production of cAMP through the RAS-cAMP-PKA pathway (a cAMP-dependent pathway) is elevated, causing protein kinase A (PKA) to inhibit its downstream target Rim15 and allow cell proliferation.
text: whereas levels of FOXA2 are high in NPCs and decrease but remain expressed at more differentiated time points.24, 25 We reasoned that high‐quality midbrain dopaminergic cells should exhibit these characteristics as cells differentiate; to test this, we assessed the levels of TH and FOXA2 at multiple time points as cells were differentiated from NPCs to more mature neurons.