Assertion: telomerase | /r/CapableOf | elongate telomere
Facets:
value: in eukaryotic cells
type: LOCATION
value: by coping an associated rna template
type: MANNER
value: within each generation
type: TEMPORAL
value: by a random amount
type: OTHER
value: on average 40 base pairs
type: OTHER
value: by extending from this group
type: MANNER
Source sentences:
text: It elongates telomeres by extending from this group using an RNA molecule, which is encoded by the Terc (telomerase RNA component) gene, as a template2,3 (Fig. 1A,C).
text: Experimental data for yeast suggest that while the telomere decreases by a fixed amount ( 3 – 4 nucleotide base pairs) per division, the telomerase elongates the telomere by a random amount (on average 40 base pairs) with the probability of an elongation event decreasing as the telomere gets longer.
text: Telomerase is a retrotranscriptase enzyme that is able to elongate telomeres by coping an associated RNA template.
text: Telomerase is active in pluripotent cells where it elongates telomeres within each generation, but is silenced after birth in the majority of tissues.
text: At each cell cycle, it binds to and elongates telomeres.
text: Telomerase is a reverse transcriptase enzyme that carries its own RNA molecule (e.g., with the sequence 3′-CCCAAUCCC-5′ in Trypanosoma brucei) which is used as a template when it elongates telomeres.
text: Telomerase is a ribonucleoprotein that elongates the telomeres in eukaryotic cells.
text: Thus, telomerase recognizes and elongates the telomere through association with the hTR template region and then translocates to the next available position for hTR binding.