Assertion: tyramine's acid amide derivative | /r/HasProperty | hydroxycinnamic
Facets:
Source sentences:
text: This invention provides tyramine containing hydroxycinnamic acid amide derivatives or analogs, and their use in modulating metabolism.
text: As used herein, the term “tyramine containing hydroxycinnamic acid amide derivative” (or “tyramine containing hydroxycinnamic acid amide analog”)
text: In some embodiments, the tyramine containing hydroxycinnamic acid amide derivative is a compound having the structure of Formula II, or an isomer, salt, homodimer, heterodimer, or conjugate thereof:
text: In other embodiments, the tyramine containing hydroxycinnamic acid amide derivative is a compound having the structure of Formula III, or an isomer, salt, homodimer, heterodimer, or conjugate thereof:
text: In further embodiments, the tyramine containing hydroxycinnamic acid amide derivative is a compound having the structure of Formula IV, or an isomer, salt, homodimer, heterodimer, or conjugate thereof:
text: In yet other embodiments, the tyramine containing hydroxycinnamic acid amide derivative is a compound having the structure of Formula V, or an isomer, salt, homodimer, heterodimer, or conjugate thereof:
text: In yet another embodiment, the tyramine containing hydroxycinnamic acid amide derivative is a compound having the structure of Formula V, or an isomer, salt, homodimer, heterodimer, or conjugate thereof:
text: In still a further embodiment, the tyramine containing hydroxycinnamic acid amide derivative is a compound having the structure of Formula VII, or an isomer, salt, homodimer, heterodimer, or conjugate thereof:
text: In a still further embodiment, the tyramine containing hydroxycinnamic acid amide derivative is a compound having the structure of Formula VIII, or an isomer, salt, homodimer, heterodimer, or conjugate thereof:
text: In a further embodiment, the tyramine containing hydroxycinnamic acid amide derivative is a compound having the structure of Formula IX, or an isomer, salt, homodimer, heterodimer, or conjugate thereof:
text: The tyramine containing hydroxycinnamic acid amide derivatives may be synthesized by the methods exemplified herein or using other similar approaches.
text: The solubility of a tyramine containing hydroxycinnamic acid amide derivative may be adjusted by changing temperature and/or the composition of the solution, for instance by removing ethanol, and/or adjusting the pH to facilitate precipitation, followed by filtration or centrifugation of the precipitated crystals or oils.
text: Biological activity of tyramine containing hydroxycinnamic acid amide derivatives can be determined using one or more of the well-known biological in vitro assays, in vivo assays and animal models described in more detail below.
text: In certain embodiments, the consumable provides between 10 and 60 mg/day of a tyramine containing hydroxycinnamic acid amide derivative.
text: While it is contemplated that individual tyramine containing hydroxycinnamic acid amide derivatives may be used in the compositions of this invention, it is further contemplated that two or more of the derivative compounds could be combined in any relative amounts to produce custom combinations of ingredients containing two or more tyramine containing hydroxycinnamic acid amide derivatives in desired ratios to enhance product efficacy, improve organoleptic properties or some other measure of quality important to the ultimate use of the product.