Assertion: trypsin | /r/HasProperty | effective
Facets:
value: at physiological ph values
type: OTHER
value: for many conditions
type: CAUSE
Source sentences:
text: There is not enough evidence to back the claims that trypsin is effective for many conditions, including:
text: Some earlier studies (10−14) have suggested that the pof the catalytic histidine is decreased during acylation (p< 7), while more recent studies (15−23) have suggested that the histidine pmust be raised (p> 11) so that it can be an effective general base catalyst during acylation and that the pof the oxyanion of the catalytic tetrahedral intermediate (THI) is lowered so that trypsin can be an effective enzyme at physiological pH values.