Assertion: prion's structure | /r/CapableOf | modify the susceptibility
Facets:
value: in turn
type: MANNER
value: to manganese
type: TRANSITIVE-OBJECT
Source sentences:
text: In contrast, the inhibitory effect of Cu2+ required binding to histidine-containing binding sites, indicating that binding of copper affects the structure of PrPC which in turn modifies the susceptibility to manganese and the ability to aggregate.