Assertion: hiv protease inhibitor ritonavir | /r/HasProperty | potent p450 inhibitor
Facets:
value: highly
type: DEGREE
Source sentences:
text: In another study in healthy male volunteers, co-administration with the HIV protease inhibitor ritonavir, which is a highly potent P450 inhibitor, at steady state (500 mg bid) with VIAGRA (100 mg single dose) resulted in a 300% (4-fold) increase in sildenafil Cmax and a 1000% (11-fold) increase in sildenafil plasma AUC.