Assertion: platelet's receptor | /r/HasProperty | switched through the pi3k pathway
Facets:
value: through reactive oxygen species
type: MANNER
Source sentences:
text: Upon activation by PDGF, these receptors dimerise, and are "switched on" by auto-phosphorylation of several sites on their cytosolic domains, which serve to mediate binding of cofactors and subsequently activate signal transduction, for example, through the PI3K pathway or through reactive oxygen species (ROS)-mediated activation of the STAT3 pathway.