Assertion: promethazine's effect | /r/AtLocation | embryofetal development study
Facets:
value: in pregnant rats
type: LOCATION
Source sentences:
text: In an embryofetal development study in pregnant rats dosed throughout the period of organogenesis, codeine increased resorptions and decreased fetal weights at a dose approximately 25 times the MRHD (on a mg/m2 basis with a maternal oral dose of 120 mg/kg/day); however, these effects occurred in the presence of maternal toxicity.