Assertion: quinine's interaction | /r/HasSubevent | toxicity
Facets:
value: to lack of efficacy
type: OTHER
Source sentences:
text: In addition, interactions with coadministered drugs can alter the serum concentration and activity of quinidine, leading either to toxicity or to lack of efficacy if the dose of quinidine is not appropriately modified (see PRECAUTIONS/Drug Interactions).