Assertion: saccharin | /r/HasProperty | carcinogenic
Facets:
value: well
type: DEGREE
value: most likely
type: DEGREE
value: in the early 1970s
type: TEMPORAL
value: in human beings
type: OTHER
value: in laboratory rats
type: LOCATION
Source sentences:
text: In 1972, studies with rats suggested that saccharin too might be carcinogenic, and the U.S. Food and Drug Administration imposed restrictions on the sweetener's use.
text: This was despite the fact that in 1974 the National Academy of Sciences performed a review of all the studies done on saccharin and determined that there was no sound evidence that saccharin was a carcinogen and that the only studies that claimed to show it was were flawed or otherwise ambiguous in their results.
text: In the 1970s, studies raised concerns that saccharin could be carcinogenic in laboratory rats.
text: Researchers in that study concluded, “Saccharin is carcinogenic for the urinary bladder in rats and mice, and most likely is carcinogenic in human beings.
text: Researchers in that study concluded, “Saccharin is carcinogenic for the urinary bladder in rats and mice, and most likely is carcinogenic in human beings.
text: I should indicate that the charge to the committee from the Food and Drug Administration was to determine when the experimental findings are sufficient to conclude that saccharin is or is not carcinogenic when administered orally to test animals, and to prepare and submit a report to the Food and Drug Administration on the safety of saccharin and saccharin salts as they are used in the human diet.
text: ly whether saccharin is or is not carcinogenic when administered orally to test animals.
text: The second reason that I believe that saccharin is most unlikely to be carcinogenic is that it is unequivocally not metabolized.
text: The Academy report states that to resolve the question of whether saccharin is or is not carcinogenic, "The following studies must be carried out.
text: Scientists found that saccharin was, "carcinogenic for the urinary bladder in rats and mice, and most likely is carcinogenic in human beings," but that study was later debunked; apparently whatever mechanism that's triggered by saccharin to cause bladder cancer only happens in rats.
text: This was despite the fact that in 1974 the National Academy of Sciences performed a review of all the studies done on saccharin and determined that there was no sound evidence that saccharin was a carcinogen and that the only studies that claimed to show it was were flawed or otherwise ambiguous in their results.
text: In the early 1970s, saccharin was thought to be a carcinogen when it was linked to bladder cancer.
text: The report presents conclusions that my wife and children might interpret as indicating that saccharin may well be a carcinogen; it has not yet been conclusively established.