Assertion: puff's microgram | /r/CapableOf | inhale in 15 healthy subjects
Facets:
value: for 7 days
type: TEMPORAL
value: twice daily
type: TEMPORAL
Source sentences:
text: Salmeterol Potent CYP3A4 inhibitors Co-administration of ketoconazole (400 mg orally once daily) and salmeterol (50 micrograms inhaled twice daily) in 15 healthy subjects for 7 days resulted in a significant increase in plasma salmeterol exposure (1.4-fold Cmax and 15-fold AUC).
text: (500 mg orally three times a day) and salmeterol (50 micrograms inhaled twice daily) in 15 healthy subjects for 6 days resulted in a small but non-statistically significant increase in salmeterol exposure (1.4-fold Cmax and 1.2-fold AUC).