Assertion: relaxin | /r/CapableOf | reduce cardiac infarct size
Facets:
value: in the pig
type: LOCATION
value: through a nos‐dependent mechanism
type: MANNER
Source sentences:
text: Relaxin protects rat lungs after ischaemia–reperfusion (IR) injury through iNOS induction (Alexiou et al. , 2013 ), reduces infarct size in rat brains by eNOS activation (Wilson et al. , 2006 ) and reduces cardiac infarct size in the pig through a NOS‐dependent mechanism (Masini et al. , 1997 ) but also reduces fibrosis when given chronically in a bleomycin‐induced lung fibrosis mouse model through an NO/cGMP‐dependent pathway (Huang et al. , 2011 ).