Assertion: osteoclast's role | /r/HasProperty | determined
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Source sentences:
text: The role of OPGL/TRANCE/RANKL on in vivo immunomodulation remains to be determined, and disruption of the OPGL gene in mouse should provide important information.
text: The innovative aspects of this project are: (1) the mechanisms by which osteoclasts modulate osteoblasts will be examined in both mice and humans, (2) the role of osteoclast-derived Wnt1 in skeletal development and osteoclast-osteoblast coupling will be determined, and (3) a new approach to evaluate gene expression in osteoblast/osteocyte/osteoclast lineage cells in vivo without in vitro manipulation will be employed.