Assertion: topical progesterone | /r/CapableOf | show no difference
Facets:
value: in a crossover study
type: OTHER
Source sentences:
text: In a crossover study, topical progesterone 40 mg twice daily showed no difference compared with oral progesterone 200 mg in the 24-hour area under the curve (AUC) for whole blood progesterone3 while another kinetic study using a daily progesterone 60 mg cream achieved serum progesterone levels similar to luteal levels (more than 3 ng/mL).11 A clinical trial evaluating the effect of progesterone on bone density found increases in serum progesterone for up to 6 months with no further accumulation.
text: In a large (N = 223), double-blind, randomized trial, topical progesterone (Progestelle) applied for over 6 months showed no difference compared with placebo for psychological, somatic, or vasomotor menopause-related symptoms.