Assertion: promethazine | /r/CapableOf | result on a mg/m2 basis
Facets:
value: at doses
type: TEMPORAL
value: in pregnant rats
type: OTHER
value: with maternal oral doses
type: OTHER
value: in delays
type: OTHER
value: in skeletal fragility of pups
type: OTHER
Source sentences:
text: In pregnant rats dosed during the period of organogenesis from gestation days 7 to 13, promethazine resulted in skeletal fragility of pups at doses approximately 3 times the MRHD (on a mg/m2 basis with maternal oral doses up to 10 mg/kg/day).
text: In pregnant rats dosed during the period of organogenesis from gestation days 10 to 12, promethazine resulted in decreased weight and delays in initial occurrence of behavioral/reflex of pups at doses approximately 3 times the MRHD (on a mg/m2 basis with maternal oral doses up to 10 mg/kg/day).