Assertion: osteoclast | /r/CapableOf | regulate osteoblastic bone formation
Facets:
value: by direct cell–cell contact
type: MANNER
value: by indirectly
type: MANNER
value: in turn
type: TEMPORAL
value: via cytokines
type: MANNER
Source sentences:
text: Besides the well-documented regulatory mechanism of osteoblast–osteoclast communication involved in bone resorption, it is now being challenged by several studies supporting the fact that osteoclasts in turn regulate osteoblastic bone formation either by direct cell–cell contact or indirectly via cytokines, however, precisely how osteoclasts regulate osteoblasts is unclear.