Assertion: small perturbation | /r/CapableOf | decrease the signal-to-raise ratio
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text: Although the specific paradoxical effect can in principle be revealed with infinitesimally small positive perturbations, in realistic experimental conditions with significant measurement noise, such small perturbations would decrease the signal-to-raise ratio, hence limiting the statistical power to infer the presence of the negative slope of response changes versus input perturbations.