Assertion: osteoclast's role | /r/HasProperty | iii
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text: These objectives were addressed by (i) determining the MMP profile selectively expressed in mouse osteoclasts in vitro and in vivo, (ii) characterizing the cooperative role of Mmp9/Mmp14 in controlling bone resorption and type I collagenolysis by mouse osteoclasts in vitro, (iii) demonstrating the utility of dual MMP9 and MMP14 blockade in regulating human osteoclast-dependent bone resorption, and (iv) defining the cooperative role of Mmp9/Mmp14 in controlling mouse osteoclast-dependent bone resorption during physiologic versus pathologic bone resorption in vivo.