Assertion: renin's effect | /r/HasProperty | fig. 1d
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text: Consistently, when we evaluated the impact of the missense variant by using several in silico tools for pathogenicity prediction (PolyPhen-2, SIFT, SDM and Mutation Taster), all programs predicted that the identified variant L381P is deleterious, thus strongly suggesting a pathogenic effect (Fig. 1d).