Assertion: prion's form | /r/HasProperty | prpc
Facets:
value: formally
type: MANNER
value: for its ability
type: CAUSE
value: commonly
type: DEGREE
Source sentences:
text: PrP exists in two forms: PrPc, the normal form of the protein, and PrPsc, the infectious form.
text: The normal form of the protein is called PrPC, while the infectious form is called PrPSc – the C refers to 'cellular' PrP, while the Sc refers to 'scrapie', the prototypic prion disease, occurring in sheep.
text: The normal form of the protein is called PrPC, while the infectious form is called PrPSc – the C refers to 'cellular' PrP, while the Sc refers to 'scrapie', the prototypic prion disease, occurring in sheep.
text: Here prions accumulate and convert normal prion proteins to the disease-causing form, PrPSc.
text: This resulting misfolded form, known formally as PrPSc, is pathogenic and aggregates in neural tissue by recruiting and converting more PrPc to PrPSc, ultimately causing neuronal cell dysfunction followed by cell death.
text: The disease-associated form of the prion protein is commonly referred to as PrPsc because it was first found in scrapie infections in sheep.
text: PrP exists in two forms, PrPc, the normal form of the protein, and PrPsc, the infectious form.
text: PrP exists in two forms, PrPc, the normal form of the protein, and PrPsc, the infectious form.
text: PrP exists in two forms, PrPc, the normal form of the protein, and PrPsc, the infectious form.
text: PrP exists in two forms, PrPc, the normal form of the protein, and PrPsc, the infectious form.
text: PrP exists in two forms, PrPc, the normal form of the protein, and PrPsc, the infectious form.
text: PrP exists in two forms, PrPc, the normal form of the protein, and PrPsc, the infectious form.
text: PrP exists in two forms, PrPc, the normal form of the protein, and PrPsc, the infectious form.
text: PrP exists in two forms, PrPc, the normal form of the protein, and PrPsc, the infectious form.
text: PrP exists in two forms, PrPc, the normal form of the protein, and PrPsc, the infectious form.
text: PrP exists in two forms, PrPc, the normal form of the protein, and PrPsc, the infectious form.
text: The normal form of the prion, PrPc, is a cell-membrane protein that may play a role in nerve signaling in the brain.
text: PrP exists in two forms, PrPc, the normal form of the protein, and PrPsc, the infectious form.
text: PrP exists in two forms, PrPc , the normal form of the protein, and PrPsc , the infectious form.
text: The normal form of the protein is called PrPC, while the infectious form is called PrPSc ” the C refers to 'cellular' or 'common' PrP, while the Sc refers to 'scrapie', a prion disease occurring in sheep.
text: The normal form of the protein is called PrPC, while the infectious form is called PrPSc —
text: The normal form of the protein is called PrPC, while the infectious form is called PrPSc— the 'C' refers to 'cellular' PrP, while the 'Sc' refers to 'scrapie,' a prion disease occurring in sheep.
text: The normal form of the protein is called PrPC, while the infectious form is called PrPSc – the C refers to 'cellular' PrP, while the Sc refers to 'scrapie', the prototypic prion disease, occurring in sheep.
text: The normal form of the protein is called PrPC, while the infectious form is called PrPSc— the 'C' refers to 'cellular' PrP, while the 'Sc' refers to ' scrapie,' a prion disease occurring in sheep.
text: The normal form of the protein is called PrPC, while the infectious form is called PrPSc —
text: The normal form of the protein is called PrPC, while the infectious form is called PrPSc ” the C refers to 'cellular' or 'common' PrP, while the Sc refers to 'scrapie', a prion disease occurring in sheep.
text: An abnormal form of the PrP protein, (called PrPSc) is found when we try to purify the agent which causes the disease from infected brain.
text: The normal form of the protein is called PrPC, while the infectious form is called PrPSc —
text: The normal form of the protein is called PrPC, while the infectious form is called PrPSc – the C refers to 'cellular' PrP, while the Sc refers to 'scrapie', the prototypic prion disease, occurring in sheep.
text: The normal form of the protein is called PrPC, while the infectious form is called PrPSc —
text: However, normal PrP can undergo a structural change to generate a disease-causing form (called PrPsc for its ability to now cause scrapie).
text: Introduction Transmissible spongiform encephalopathies (TSEs) or prion diseases are caused by conformational transitioning of the physiological host-encoded prion protein, PrPC, into a misfolded and aggregated form, PrPSc that accumulates in the brain in the form of plaques or smaller plaque-like deposits .
text: Figure 6.25 Endogenous normal prion protein (PrPc) is converted into the disease-causing form (PrPsc) when it encounters this variant form of the protein.
text: Figure \(\PageIndex{2}\): Endogenous normal prion protein (PrPc) is converted into the disease-causing form (PrPsc) when it encounters this variant form of the protein.
text: The incubation periods ranged from 340 days to 626 days, and these mice had the protease-resistant form PrpSc, of a host-coded glycoprotein, PrPc .
text: This resulting misfolded form, known formally as PrPSc, is pathogenic and aggregates in neural tissue by recruiting and converting more PrPc to PrPSc, ultimately causing neuronal cell dysfunction followed by cell death.