Assertion: relaxin's role | /r/CapableOf | bind dht
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text: The Role of Androgens in Prostate Cancer AR is a nuclear receptor that binds androgenic hormones, testosterone and DHT, and is directly involved in the regulation of a multitude of cellular functions, including apoptosis, cell cycle, adhesion, ECM remodeling and metabolism, by modulating the transcription of several genes in the human prostate.3 Binding of testosterone or DHT to AR induces its dimerization, which then enables it to bind AR response elements in the nuclear DNA and recruit a number of different co‐regulators of transcription.