Assertion: osteoclast's role | /r/HasProperty | underscored by recent findings
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text: The crucial role of the RANKL/RANK/OPG signalling pathways in regulating bone metabolism is underscored by recent findings that genetic mutations that activate RANK or inhibit the RANKL binding properties of OPG in humans are associated with familial forms of hyperphosphatasia and bone abnormalities68,69,70,71,72.