Assertion: topical progesterone | /r/CapableOf | apply for over 1 year
Facets:
value: in an open-label study
type: LOCATION
Source sentences:
text: In an open-label study, topical progesterone 40 mg daily applied for over 1 year did not provide adequate opposition to endometrial hyperplasia as determined by endometrial histology and bleeding patterns in 41 postmenopausal women.20, 21 A small clinical crossover trial (N = 26) found topical progesterone 40 mg daily to exert a similar effect on the endometrium as standard oral progesterone.22