Assertion: platelet's protein | /r/HasProperty | tgf-β
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text: Alpha granules contain numerous proteins and growth factors, such as platelet-derived growth factor (PDGF), TGF-β, platelet factor-4 (also referred to as CXCL4), and vWF, which are synthesized in the megakaryocyte.16 Other proteins, such as fibrinogen, enter the alpha granules from the plasma via GPIIb-IIIa receptor–mediated endocytosis.17 P-selectin (CD62P), an adhesion molecule, also is localized in the membrane of alpha granules18 and redistributes to the cell surface during platelet activation.