Assertion: osteoclast | /r/CapableOf | resorb bone
Facets:
value: actively
type: MANNER
value: at the graft/implant site
type: LOCATION
value: on slices
type: LOCATION
Source sentences:
text: This extensively folded or ruffled border facilitates bone removal by dramatically increasing the cell surface for secretion and uptake of the resorption compartment contents and is a morphologic characteristic of an osteoclast that is actively resorbing bone.
text: With estrogen deficiency, the osteoclasts live longer and are therefore able to resorb more bone.
text: Osteoblasts form bone; osteoclasts resorb bone.
text: Initial studies indicated that osteoclasts could resorb bone on slices prepared from tetracycline-labeled bone, although tetracyclines have been reported to have some inhibitory effect on bone resorption (15).
text: Loss-of-function mutations that cause osteopetrosis in both humans and mice provide insights into the mechanisms by which osteoclasts are recruited to and resorb bone.
text: Osteoblasts form bone; osteoclasts resorb bone.
text: The ruffled border, which facilitates removal of the bony matrix, is a morphologic characteristic of an osteoclast that is actively resorbing bone.
text: These questions are due to the unwanted side effect of BMPs on other cell types, such as osteoclasts which can resorb bone at the graft/implant site.
text: This extensively folded or ruffled border facilitates bone removal by dramatically increasing the cell surface for secretion and uptake of the resorption compartment contents and is a morphologic characteristic of an osteoclast that is actively resorbing bone.
text: Not only do osteoclasts resorb bone, but they are also considered to regulate osteoblast differentiation in the bone‐remodeling process in vivo.
text: In mature cells, a low level of expression is required for osteoclasts to resorb bone.
text: The embryonic development of the mammalian skeleton and the maintenance of skeletal and calcium homeostasis during adult life is dependent on the continuous interaction between osteoclasts, which degrade or resorb bone, and osteoblasts, which form bone.
text: In mouse models where osteoclasts are present but are not able to resorb bone (c-Src or chloride-7 channel knockout mice), there is no defect in bone formation (4–6).
text: Force applied to the compression side of the periodontal membrane induces osteoclasts and the tooth moves as osteoclasts resorb bone.
text: To resorb bone, the osteoclasts attach to the bone matrix, their cytoskeleton reorganizes, and they assume polarized morphology and form ruffled borders to secrete acid and collagenolytic enzymes and a sealing zone to isolate the resorption site.
text: Osteoclasts are multinucleated cells that resorb bone ( 1 ).