Assertion: osteoclast | /r/HasProperty | derived
Facets:
value: from the same cells
type: OTHER
value: from the hematopoietic lineage
type: OTHER
value: from cells in the bone marrow
type: LOCATION
Source sentences:
text: It may be important to note that while osteoclasts are derived from the hematopoietic lineage, osteoblasts are derived from mesenchymal stem cells.
text: Osteoclasts are derived from circulating cells such as monocytes and macrophages.
text: While osteoblasts and osteocytes have the same source, and are, in fact, different stages of the same cells, osteoclasts are derived from cells in the bone marrow.
text: The osteoclast is derived from the monocyte/macrophage lineage (2), and it therefore follows that genes regulating the maturation of these mononuclear cells would also modulate the osteoclast.
text: Osteoblasts and osteocytes are derived from osteoprogenitor cells, but osteoclasts are derived from the same cells that differentiate to form macrophages and monocytes.
text: Because the osteoclasts are derived from a monocyte stem-cell lineage, they are equipped with phagocytic-like mechanisms similar to circulating macrophages.
text: Osteoblasts and osteocytes are derived from osteoprogenitor cells, but osteoclasts are derived from the same cells that differentiate to form macrophages and monocytes.
text: Because the osteoclasts are derived from a monocyte stem-cell lineage, they are equipped with phagocytic-like mechanisms similar to circulating macrophages.
text: Because the osteoclasts are derived from a monocyte stem-cell lineage, they are equipped with phagocytic-like mechanisms similar to circulating macrophages.
text: While both osteoclasts and osteal macrophages, F4/80+ which account for the galectin-3 negative bone-associated donor cells, are derived from myeloid precursors, over-representation of donor cells was not observed in osteal macrophages.
text: It may be important to note that while osteoclasts are derived from the hematopoietic lineage, osteoblasts are derived from mesenchymal stem cells.
text: Because osteoclasts are derived from hematopoietic stem cells, we sought to establish the requirements for osteoclast precursor cell generation and differentiation.
text: The origins of these cells are well established: whereas osteoblasts are derived from mesenchymal stem cells, osteoclasts are highly specialized, multinucleated cells that are derived from hematopoietic stem cells, specifically from cells of the monocyte-macrophage lineage.
text: Osteoclasts are large, multinucleated cells involved in bone resorption, and they are derived when hematopoietic progenitor differentiates mononuclear TRAP-positive preosteoclast cells and fuses the multinucleated mature osteoclasts .
text: Osteoblasts, which are derived from mesenchymal stem cells (MSCs), are ultimately responsible for bone formation; osteoclasts are derived from pluripotent haematopoietic cells and are capable of resorbing bone.