Assertion: pindolol | /r/HasProperty | effective
Facets:
value: as monotherapy
type: MANNER
value: in patients
type: OTHER
value: highly
type: DEGREE
value: as a standalone antidepressant
type: MANNER
value: for accelerating responses to antidepressant treatment
type: PURPOSE
value: as α-methyldopa
type: OTHER
value: as chlorthalidone
type: OTHER
value: as hydrochlorothiazide
type: OTHER
value: as propranolol
type: OTHER
value: in reducing the supine
type: TRANSITIVE-OBJECT
value: equally
type: DEGREE
value: as an antidepressant adjunct
type: MANNER
value: approximately
type: DEGREE
Source sentences:
text: As monotherapy, pindolol is as effective as propranolol, α-methyldopa, hydrochlorothiazide, and chlorthalidone in reducing systolic and diastolic blood pressure.
text: Although pindolol is an effective for accelerating responses to antidepressant treatment, there may be superior alternatives.
text: The effect on blood pressure is not orthostatic, i.e., pindolol was equally effective in reducing the supine and standing blood pressure.
text: As monotherapy, pindolol is as effective as propranolol, α-methyldopa, hydrochlorothiazide, and chlorthalidone in reducing systolic and diastolic blood pressure.
text: The effect on blood pressure is not orthostatic, i.e., pindolol was equally effective in reducing the supine and standing blood pressure.
text: Moreover, in a subset of patients, pindolol may potentiate the therapeutic effect of conventional antidepressants and could be effective as a monotherapy.
text: Though pindolol may be effective for enhancing the efficacy of antidepressants over a short-term, enhancement of efficacy may be unsustainable over the long-term.
text: : Though pindolol may be effective for enhancing the efficacy of antidepressants over a short-term, enhancement of efficacy may be unsustainable over the long-term.
text: There’s evidence to suggest that pindolol is highly effective in patients naïve to antidepressant therapy, but relatively useless among those with treatment-resistant depression.
text: There’s evidence to suggest that pindolol is highly effective in patients naïve to antidepressant therapy, but relatively useless among those with treatment-resistant depression.
text: Some suspect that pindolol could be effective as a standalone antidepressant, thus eliminating the need for conventional, first-line options (e.g. SSRIs).
text: Some suspect that pindolol could be effective as a standalone antidepressant, thus eliminating the need for conventional, first-line options (e.g. SSRIs).
text: Study designs : To accurately determine whether pindolol is effective as an antidepressant adjunct or as a monotherapy, further studies are warranted.
text: Pindolol is approximately as effective as propranolol in the therapy of hypertension, but in some crossover trials central nervous system side effects were more frequent with pindolol.
text: : Although pindolol is an effective for accelerating responses to antidepressant treatment, there may be superior alternatives.