Assertion: sertraline | /r/CapableOf | act on the enzyme
Facets:
value: directly
type: MANNER
Source sentences:
text: Sertraline has been found to directly act on the enzyme 3α-hydroxysteroid dehydrogenase (3α-HSD) and modulate its activity, thereby enhancing the conversion of 5α-dihydroprogesterone into the neurosteroid allopregnanolone and thus increasing the production of allopregnanolone in the brain.