Assertion: polypeptide's amino acid | /r/HasAspect | same charge
Facets:
Source sentences:
text: Specifically, for example, when modifying the heavy chain constant region, EU numbering positions 356 and 439, 357 and 370 in the amino acid sequence of the heavy chain constant region of the polypeptide having the first antigen-binding activity, and EU of the heavy chain constant region of a polypeptide having the second antigen-binding activity or not having the antigen-binding activity, by modifying at least one of the combination of positions 399 and 409 to an amino acid having the same charge