Assertion: pyridine's derivative | /r/MadeOf | active adamantyl
Facets:
value: with unsubstituted imidazo[1,2-a]pyridine ring
type: OTHER
value: biologically
type: MANNER
Source sentences:
text: The present imidazo[1,2-a]pyridine derivatives contain biologically active adamantyl, biphenyl or phenyl moiety as their side chains, which showed different levels of inhibitory activities towards AChE and BChE. Compounds 2a, 2f, 2j and 2l with unsubstituted imidazo[1,2-a]pyridine ring were synthesized as the reference compounds to accentuate the electronic effects of different substituents on the imidazo[1,2-a]pyridine ring, i.e. electron-donating (CH 3 ) and electron-withdrawing (Cl) groups, upon their cholinesterase inhibitory activities.