Assertion: osteoclast | /r/HasProperty | sensitive to forced cholesterol removal
Facets:
value: highly
type: DEGREE
Source sentences:
text: They show that cholesterol acceptors, including high-density lipoprotein, induce osteoclast apoptosis; that osteoclasts deficient in the low-density lipoprotein receptor (LDLR), in the presence of M-CSF and RANKL, undergo apoptotic cell death at an increased rate compared with wild-type osteoclasts; and that osteoclasts are highly sensitive to forced cholesterol removal because of the absence of an endogenous cholesterol biosynthesis feedback response.