Assertion: osteoclast's activity | /r/AtLocation | part
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text: A recent study using Erk1−/− and Erk2flox/flox mice reported that Erk1 positively regulated osteoclast function (He et al., 2011), providing grounds for our proposal that the increased bone-resorbing activity of Stat5 KO osteoclasts is, at least in part, caused by the increased activity of ERK.