Assertion: polypeptide | /r/HasAspect | third antigen-binding activity
Facets:
Source sentences:
text: Polypeptides having a third antigen-binding activity” and “polypeptides having a fourth antigen-binding activity” described later can be similarly expressed.
text: Accordingly, the present invention includes a polypeptide having a first antigen binding activity, a polypeptide having a second antigen binding activity, a polypeptide having a third antigen binding activity, and a polypeptide having a fourth antigen binding activity.
text: (A) DNA encoding a polypeptide having a first antigen-binding activity, DNA encoding a polypeptide having a second antigen-binding activity, a polypeptide having a third antigen-binding activity, and a fourth antigen-binding activity
text: (A) DNA encoding a polypeptide having a first antigen-binding activity, DNA encoding a polypeptide having a second antigen-binding activity, a polypeptide having a third antigen-binding activity, and a fourth antigen-binding activity Providing a DNA encoding a polypeptide having:
text: The polypeptide having the third antigen-binding activity and the polypeptide having the fourth antigen-binding activity of the present invention can contain the amino acid sequence of the antibody light chain constant region.
text: The polypeptide having the third antigen-binding activity is modified by changing the Kabat numbering 39th in the heavy chain variable region of the polypeptide and / or EU numbering 213 in the heavy chain constant region to amino acids having opposite charges, respectively.
text: (A) DNA encoding a polypeptide having first antigen-binding activity, DNA encoding a polypeptide having second antigen-binding activity, and DNA encoding two polypeptides having third antigen-binding activity
text: (A) DNA encoding a polypeptide having first antigen-binding activity, DNA encoding a polypeptide having second antigen-binding activity, and DNA encoding two polypeptides having third antigen-binding activity Providing the process,
text: (A) DNA encoding a polypeptide having first antigen-binding activity, DNA encoding a polypeptide having second antigen-binding activity, and DNA encoding two polypeptides having third antigen-binding activity
text: The present invention also provides a polypeptide having a first antigen binding activity, a polypeptide having a second antigen binding activity, a polypeptide having a third antigen binding activity, and a polypeptide having a fourth antigen binding activity.