Assertion: prion | /r/HasProperty | protein
Facets:
value: simply
type: DEGREE
value: with no genetic material
type: OTHER
value: with a defective structure
type: OTHER
value: as far as we know
type: OTHER
value: alone
type: MANNER
Source sentences:
text: A prion, simply put, is a protein that has attained an abnormal conformation that enables it to cause disease.
text: Prions are composed of an isoform of the prion protein (PrP) and since prions lack nucleic acid the infectious agent is the protein alone.
text: A prion is (as far as we know) just a protein.
text: We know infections from bacteria of viruses that can reproduce using DNA and/or RNA, something a prion (essentially just a protein) doesn't have.
text: A prion is a protein that occurs normally in a harmless form.
text: A prion is a protein that occurs normally in a harmless form.
text: A prion is a protein that has been mutated.
text: Without the nucleus, it is not a virus or bacteria; it is only a protein (Hinz, A., Doremus, C., 1997).
text: A prion is a protein where the amino acid sequence or primary structure remains unchanged from that of a normal protein but the conformation has been changed by misfolding at the secondary and tertiary levels of protein structure.
text: Prion is protein-only, which explained why the agents were resistant to procedures that usually break down nucleic acid and destroy biological forms of other pathogens.
text: Prions are proteins that change shape and shift tasks, and then trigger other proteins to make the same change.
text: Prions are proteins with a defective structure that also trigger other proteins to adopt this faulty structure.
text: Prions, by contrast, are just proteins, with no genetic material.
text: Prions are proteins that can invade cells and somehow direct their own duplication, making more of the isolated proteins.
text: There is no DNA/RNA as in the case of an infectious virus, prions are simply proteins that have gone rogue.
text: Prions are proteins that present alternative configurations to their normal shape, but the critical distinguishing feature of prions is that the protein becomes self-propagating.
text: The discovery more than a quarter century ago that prions were proteins, devoid of nucleic acids, upended what scientists assumed not only about disease transmission, but about life itself.
text: Prions are the proteins that cause Mad Cow Disease also known as BSE.