Assertion: serotonin | /r/HasProperty | recognized as metabotropic effector
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text: Serotonin, as metabotropic effector, has been recognized as a trophic factor, particularly during development including morphogenetic activities as cell proliferation, migration and differentiation ; during adulthood, depletion in serotonin decreases neurogenesis in the dentate gyrus  though 5-HT plays a critical role in the neuronal organization of the hippocampus .