Assertion: ritonavir | /r/HasProperty | pharmacologic boosters
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text: Both lopinavir/ritonavir and darunavir/cobicistat are strong inhibitors of CYP3A4, as well as being inhibitors of other drug-metabolizing enzymes and drug transporters such as P-glycoprotein (in fact, ritonavir and cobicistat are pharmacologic "boosters" that are used to intentionally inhibit drug metabolism).