Assertion: ritonavir | /r/HasProperty | rtv
Facets:
Source sentences:
text: Ritonavir (RTV), sold under the trade name Norvir, is an antiretroviral medication used along with other medications to treat HIV/AIDS.
text: Dosing Recommendations Selected Adverse Events Ritonavir as a Pharmacokinetic Enhancer: Ritonavir (RTV) is used as a pharmacokinetic enhancer of other protease inhibitors (PIs).
text: Metabolism: Ritonavir (RTV) is extensively metabolized by (and is one of the most potent inhibitors of) hepatic cytochrome P450 (CYP)
text: Remdesivir (RDV), lopinavir (LPV), and ritonavir (RTV) were solubilized in 100% DMSO and provided by Gilead Sciences,
text: LPV requires a higher dose of ritonavir (RTV) than some other protease inhibitors (PIs); this higher dose may exacerbate these adverse events (AEs).
text: LPV requires a higher dose of ritonavir (RTV) than some other protease inhibitors (PIs); this higher dose may exacerbate these adverse events (AEs).
text: The fixed-dose formulation of lopinavir (LPV) and ritonavir (RTV) utilizes RTV's potent inhibition of CYP3A activity to enhance the systemic exposure of LPV.2 CYP3A is the major enzyme subfamily responsible for the metabolism of most PIs and nonnucleoside reverse transcriptase inhibitors.
text: Ritonavir (RTV) was neither mutagenic nor clastogenic in a series of in vitro and animal in vivo screening tests.
text: Neither lopinavir (LPV) nor ritonavir (RTV) was found to be mutagenic or clastogenic in a battery of in vitro and in vivo assays.