Assertion: osteocyte | /r/HasProperty | induced prostaglandin e
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text: Osteocytes have been considered to activate bone formation, because osteocytes induced anabolic factors, such as prostaglandin E 2 (PGE 2 ), prostaglandin I 2 (PGI 2 ), nitric oxide (NO), cyclooxygenase-2 (COX-2), and endothelial nitric oxide synthase (ecNOS), after application of mechanical stimuli in vitro  and bone formation was severely inhibited after osteocyte ablation  .