Assertion: local anesthetic | /r/HasProperty | given in high volumes
Facets:
value: epidurally
type: DEGREE
Source sentences:
text: When given in high volumes epidurally or spinally, local anesthetics can cause excessive blockade of sympathetic neurons, resulting in hypotension, and excessive blockade of motor neurons, resulting in paralysis of intercostal muscles and the diaphragm.1,2