Assertion: melatonin's benefit | /r/HasProperty | documented in small trials
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text: Limited data suggest a potential benefit of melatonin supplementation on sleep and delirium in ICU patients.147, 151 Modest but insignificant effects on sleep have been documented in small trials where melatonin 3 mg × 3 days significantly increased plasma levels but failed to produce significant impacts on sleep, delirium, or agitation.150, 151