Assertion: ngf's activity | /r/HasProperty | required for its rapid turnover
Facets:
value: in hela cells
type: LOCATION
Source sentences:
text: It has previously been reported that the catalytic activity of caspase-3 is required for its rapid turnover in HeLa cells and that stabilisation of the active complex with caspase inhibitor abrogated the turnover of active caspase-3.36 Using the pan-caspase inhibitor carbobenzoxy-valyl-alanyl-aspartyl-[O-methyl]-fluoromethylketone (zVAD-fmk), we investigated whether this was also the case for NGF-stimulated removal of p17.36 Inhibition of TG-induced DEVDase activity by zVAD-fmk was initially confirmed (Supplementary Figure S4A).