Assertion: lactic acid | /r/CapableOf | inactivate t and nk cells
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text: It was reported that lactic acid can cause an immunosuppressive TME via various mechanisms, such as promoting the polarization of M2 macrophages by the maintenance of HIF‐1α protein, inactivating T and NK cells via the downregulation of the nuclear factor of activated T cells (NFAT), as well as decreasing proinflammatory cytokines secretion through the inhibition of the NF‐kB pathway.12-15