Assertion: bone marrow's cell | /r/CapableOf | penetrate outer cortex
Facets:
Source sentences:
text: osteogenic cells lining entire inner surface of bone muscular insertion (onto periosteum): broad (as opposed to narrow attachment of tendon); collagen fibers of endomycium mingles with those of periosteum, look for perforating fibers (Sharpey's fibers) marrow: intertrabecular spaces sources of blood cells and B lymphocytes nutrient artery: reaches marrow through nutrient canal (pierces cortical bone) periosteal capillaries: penetrate outer cortex and anastomose with nutrient artery-derived vessels; reenter marrow cavity to form sinusoidal plexus extending throughout marrow; drainage: marrow sinusoids drain into large central sinus; drains from bone as emissary vein through nutrient canal bone matrix & mineralization: hole zones: within collagen type I; initial site of mineral deposition; osteocalcin (Gla protein): noncollagen organic material, binds calcium during mineralization osteonectin: serves bridging function between collagen and mineral component sialoproteins: rich in sialic acid; concentrated from plasma hydroxyapatite: mineral component of bone; calcium and phosphate; conjugated to small proportion magnesium carbonate, sodium and potassium ions; affinity for heavy metal and radioactive environmental pollutants; note: 20% or more of mineral component remains amorphous pyrophosphate: inhibitor calcium deposition; crucial for controlling bone mineralization matrix vesicles: membrane bound vesicles derived from osteoblast plasma membrane; contain alkaline phosphatase and other phosphatases; neutralize effect of pyrophosphate.