Assertion: leucine | /r/CapableOf | act as nutritional sign
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text: Previous studies have pointed out to cardiac protection with leucine as a therapy strategy in different models of systolic dysfunction, suggesting that leucine acts as a nutritional sign to stimulate protein synthesis in cardiac muscle, increasing the availability of the eukaryotic initiation factor (eIF4B) and activating via p70S6K and mTOR cardiac, a fact that can have attenuated damages observed in the doxorubicin group (Escobar et al., 2006; Canedo et al., 2010).