Assertion: ligand's activity | /r/HasProperty | low
Facets:
value: very
type: DEGREE
value: in their absence
type: TEMPORAL
Source sentences:
text: Some allosteric activators are referred to as "essential", or "obligate" activators, in the sense that in their absence, the activity of their target enzyme activity is very low or negligible, as is the case with N-acetylglutamate's activity on carbamoyl phosphate synthetase I, for example.
text: In general, the higher the concentration of inhibitor, the more agonist activity will be lowered.
text: If the specific activity is low, concentration above Kd value can be used but it must never be at or higher than saturating concentration.