Assertion: ngf | /r/CapableOf | block antibody
Facets:
value: in the curative protocol
type: OTHER
Source sentences:
text: Finally, we conducted experiments in rats to determine whether anti-NGF blocking antibodies administered in vivo prevented and/or reversed pulmonary arterial hyperreactivity, remodeling, and inflammation in CH- or MCT-induced PH.
text: This increase was not significantly modified when rats were treated with nonrelevant antibodies, but was partially or totally reversed when rats were treated with anti-NGF blocking antibodies in the curative protocol ( P < 0.01 or 0.001 vs. CH or MCT)
text: To validate these findings, we subsequently studied whether anti-NGF blocking antibodies administered in vivo would prevent and/or reverse experimental PH.
text: In the next hour, the medium was replaced by 2 ml of the same medium containing K-252a (an alkaloïd-like trkA inhibitor) or MAB-256 (anti-NGF blocking antibody) at different concentrations, in order to study the effect of pharmacological inhibitor or blocking antibody on the basal level of growth.