Assertion: methadone's index | /r/HasProperty | avoided
Facets:
Source sentences:
text: Concurrent use of enzalutamide with CYP3A4 substrates that have a narrow therapeutic index should be avoided.
text: Use of stiripentol with CYP3A4 substrates that are considered to have a narrow therapeutic index should be avoided due to the increased risk for adverse effects and toxicity.