Assertion: ketamine's antidepressant effect | /r/HasProperty | mediated by increase
Facets:
value: in glutamate
type: OTHER
Source sentences:
text: 304 320 321 Antidepressant effects of ketamine may be mediated by an increase in glutamate, which leads to a cascade of events that results in synaptogenesis and reversal of the negative effects of chronic stress and depression, particularly in the prefrontal cortex.