Assertion: local anesthetic's effect | /r/HasProperty | proportional
Facets:
value: to the drugs
type: OTHER
value: directly
type: MANNER
value: to the concentration of methemoglobin
type: OTHER
Source sentences:
text: In addition, methemoglobin shifts the oxygen-hemoglobin dissociation curve to the left and changes the sigmoid shape of the curve into a more hyperbolic one, thus hindering unloading of oxygen to tissues.1 These effects are proportional to the concentration of methemoglobin and are reversible.
text: This depressant effect is directly proportional to the drugs relative potency (see chart).