Assertion: methadone | /r/CapableOf | work opioid receptors
Facets:
value: in the brain
type: LOCATION
value: fully
type: MANNER
value: as morphine
type: OTHER
value: as heroin
type: MANNER
value: to stabilize patients
type: PURPOSE
value: as a full opioid agonist
type: MANNER
value: in a way
type: MANNER
value: on the mu
type: LOCATION
Source sentences:
text: Methadone is a long-lasting synthetic opioid agonist that works on the mu opioid receptors in the brain in a way similar to heroin, but with a slower onset and longer duration of action.
text: Methadone acts on the brain's opioid receptors as a full opioid agonist, making it effective at curbing cravings and withdrawal symptoms in users who have developed physical dependence on opioids.
text: Methadone acts on the same opioid receptors as morphine and heroin to stabilize patients and minimize withdrawal symptoms in the case of an addiction.
text: Methadone attaches fully to the opioid receptors in the brain, and at an appropriate dose, does not create the euphoria or “high” illicit opioids create.