Assertion: lysosome's lumen | /r/HasSubevent | negative δψ
Facets:
value: highly
type: DEGREE
Source sentences:
text: The pumping of Hinto the lumen by the vacuolar Hpump (V-ATPase) to achieve acidic pH leads to a highly negative ΔΨ (lumen more positive), in turn limiting the Hpumping ability of the V-ATPase due to increased proton motive force, unless the high ΔΨ is dissipated by influx of anions and/or efflux of cations.