Assertion: t lymphoblast | /r/HasAspect | a high-affinity α4-integrin
Facets:
value: on their surface
type: LOCATION
Source sentences:
text: As encephalitogenic T lymphoblasts have a high-affinity α4-integrin on their surface as demonstrated by binding soluble recombinant VCAM-1 (Vajkoczy et al., 2001), we asked whether T-cell recruitment across the BBB works via a shortcut of the “multistep paradigm,” where the high-affinity α4-integrin mediates both the initial capture and the subsequent adhesion strengthening of T lymphoblasts on endothelial VCAM-1 without the necessity of in situ activation of the α4-integrin.