Assertion: ngf | /r/CapableOf | play role
Facets:
value: in male fertility
type: LOCATION
value: by binding to its receptors
type: MANNER
value: in many organs
type: LOCATION
value: in memory
type: MANNER
value: in the hyperalgesia
type: LOCATION
value: in neuronal plasticity
type: OTHER
value: in learning
type: TEMPORAL
value: in visual cortex
type: LOCATION
value: in the optical system
type: LOCATION
value: in cell survival
type: PURPOSE
value: in wound healing
type: TEMPORAL
value: in coronary atherosclerosis
type: LOCATION
value: in metabolic syndrome
type: OTHER
value: in obesity
type: OTHER
value: in type 2 diabetes
type: OTHER
value: in inflammation
type: OTHER
value: in endogenous neuroprotection
type: OTHER
value: in cartilage repair
type: OTHER
value: through ngf-abs
type: MANNER
value: in certain types of clbp
type: LOCATION
value: in painful degenerating discs
type: LOCATION
value: in oa pain pathogenesis
type: OTHER
Source sentences:
text: Research suggests that NGF may play a role in regulating the interactions of the nervous system, hormonal system, and immune system, keeping it in balance.
text: NGF plays its role by binding to its receptors located
text: Nerve Growth Factor appears to play a role in male fertility, as well as female fertility as it is a well-represented component of semen.
text: It is clear, however, that NGF plays a role in OA pain pathogenesis, as evidenced by the demonstrated ability of NGF-Abs to attenuate pain (or pain-related behavior) in animal models of OA, pilot veterinary (cat and dog) trials of degenerative joint disease, and in clinical trials of OA.77,103
text: This suggests that NGF may play a role in painful degenerating discs, although the exact contribution of NGF in CLBP of this, and other, etiologies is not completely understood.
text: The efficacy observed in some clinical trials of NGF-Abs suggests that NGF plays a role in certain types of CLBP.
text: It is also possible that NGF may play a role in cartilage repair and load-induced bone formation.114,115 Inhibition of NGF activity through NGF-Abs would be believed to, potentially, inhibit these processes and contribute to RPOA.
text: The possibility that NGF in concert with other pro-cancer biological mediators might play a role in cell survival cannot be excluded, but this effect and the underlined mechanisms need to be identified.
text: In this review, we consider evidence supporting these criteria and conclude that NGF does play a role in endogenous neuroprotection.
text: Therefore, it is believed that NGF can play a role by inducing the synthesis of oxygen radical scavengers.
text: Altogether, these ex vivo and in vitro results indicate that NGF may contribute to pulmonary arterial altered reactivity and remodeling occurring in PH, and that NGF may also play a role in inflammation associated with PH.
text: As LSCs are known to replenish the corneal epithelium 2-8, it is likely that NGF and its receptors play a role in the regulation of the LSC niche.
text: NGF also plays a role in coronary atherosclerosis, type 2 diabetes, obesity, wound healing, and metabolic syndrome.
text: NGF also plays a role in neuronal plasticity in the optical system or visual cortex where monocular deprivation leads to decreased cell size and impairment of synaptic plasticity in visual cortex, while intraventricular administration of NGF prevents the cell shrinkage and demonstrated a substantial recovery of functional binocular connections .
text: Recent studies have shown that NGF plays a role in learning and memory, and experiments conducted by Cattaneo’s and Calissano’s research groups demonstrate that removal of NGF in either in vivo or in vitro experimental models results in the onset of an Alzheimer-like molecular syndrome, which leaves many hopeful that NGF and other neurotrophins may be useful for treating Alzheimer’s disease.
text: There is increasing evidence that NGF plays a role in the hyperalgesia associated with inflammation.
text: Besides its role in the CNS, there is evidence that NGF circulates throughout the body and plays roles in many organs .
text: NGF plays its role by binding to its receptors located in the surface of cells.
text: Nerve Growth Factor appears to play a role in male fertility, as well as female fertility as it is a well-represented component of semen.