Assertion: methadone's life | /r/HasProperty | long half-
Facets:
value: extremely
type: DEGREE
Source sentences:
text: Heroin has a very short half-life, while methadone has a long half-life.
text: Methadone may accumulate due to its long half life; if sedation occurs, withhold doses until sedation resolves and consider reduction in dose and/or increasing the dosing interval (eg, every 8 to 12 hours).
text: However, because methadone has a long half-life, individual wide variations, and potential for accumulation and overdosage, physicians must judiciously and conscientiously prescribe it.
text: Methadone has a long half-life and can accumulate in the plasma.
text: Methadone has an extremely long half-life, which made it a preferred drug for tapering people off opioids like heroin.
text: Finally, because methadone has a long half-life and is known to be eliminated from the body slowly, risk of overdose exists.