Assertion: immunoglobulin | /r/HasProperty | purified
Facets:
Source sentences:
text: In order to keep the purification process as simple as possible, in a preferred embodiment the pre-cleaning step is performed in the flow-through mode, i.e. the immunoglobulin to be purified is not bound by the resin and thus obtained in the flow-through fraction, while impurities are to a large extent retained on the resin and thereby separated from the immunoglobulin.
text: The term "binding mode" or "bind and elute mode" refers to chromatography conditions in which a sample containing the immunoglobulin to be purified is applied to a chromatography medium, wherein the immunoglobulin binds to the chromatography medium.
text: In the experiments which lead to the present invention it was observed that the cell- free harvest material (clarified supernatant) still contains several substances that, along with the immunoglobulin to be purified, bind strongly to the capture resin.