Assertion: immunoglobulin's region | /r/HasProperty | variable
Facets:
value: quite
type: DEGREE
value: except for certain specific hypervariable loops
type: OTHER
value: in their three dimensional folding pattern
type: OTHER
value: in their sequences
type: LOCATION
Source sentences:
text: Though the general structure of all antibodies is very similar, a small region at the tip of the protein is extremely variable, allowing millions of antibodies with slightly different tip structures, or antigen-binding sites, to exist.
text: The immunoglobulins of the invention which are devoid of light chains, nevertheless comprise on their heavy chains a constant region and a variable region.
text: The N‐terminal regions of heavy and light chains, known as variable (V) region, are highly variable in their sequences and are the antigen‐binding portions of the antibody.
text: The immunoglobulins of the invention which are devoid of light chains, nevertheless comprise on their heavy chains a constant region and a variable region.
text: The immunoglobulins of the invention which are devoid of light chains, nevertheless comprise on their heavy chains a constant region and a variable region.
text: In a particular group of these immunoglobulins each heavy polypeptide chain contains one antigen binding site on its variable region, and these sites correspond to the same amino-acid sequence.
text: In a particular group of these immunoglobulins each heavy polypeptide chain contains one antigen binding site on its variable region, and these sites correspond to the same amino-acid sequence.
text: The immunoglobulins of the invention which are devoid of light chains, nevertheless comprise on their heavy chains a constant region and a variable region.
text: Most variable regions of antibodies of a given class are in fact quite constant in their three dimensional folding pattern, except for certain specific hypervariable loops.
text: In a further embodiment of the invention the immunoglobulins are characterized in that their heavy polypeptide chains contain a variable region (V HH ) and a constant region (C H ) according to the definition of Roitt et al, but are devoid of the first domain of their constant region.
text: In a further embodiment of the invention the immunoglobulins are characterized in that their heavy polypeptide chains contain a variable region (V HH ) and a constant region (C H ) according to the definition of Roitt et al, but are devoid of the first domain of their constant region.