Assertion: hyperkalemia's effect | /r/AtLocation | patient
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text: This clinically relevant adverse effect is most likely to occur in patients who have chronic kidney disease, have a comorbid condition that increases their risk for electrolyte abnormalities, use K+ sparing diuretics, use K+supplements or use K+ containing salt substitutes.11,12 Overall, the discontinuation rate for ACE inhibitors evaluated in clinical trials is very low or not related to changes in serum K+ levels.13