Assertion: liposome's drug | /r/HasProperty | hydrophilic
Facets:
Source sentences:
text: If the drug is hydrophilic it is included in the aqueous buffer and if the drug is hydrophobic, it can be included in the lipid film.
text: Despite the different physicochemical characteristics of the two studied drugs (one hydrophilic and one hydrophobic) and the different lipid/ cholesterol combinations, common performances were detected for each type of lipids: (1) the hydrophilic drug (A) is released faster than hydrophobic drug (Q), (2) the formulation with the higher amount of cholesterol when A was loaded had recorded the faster release, (3) the combination with a higher amount of cholesterol when Q was added had shown the slower release and (4) an initial burst release was observed as expected at an incubation temperature of 37 °C .
text: In theory, liposomes should make an ideal drug delivery system since they can isolate nearly any hydrophilic drug, can be grafted with molecules to target specific tissues and can be relatively non-toxic since the body possesses biochemical pathways for degrading lipids.