Assertion: ketamine's use | /r/HasSubevent | tolerance
Facets:
value: commonly
type: TEMPORAL
Source sentences:
text: Prolonged use can lead to tolerance and psychological addiction.
text: Ketamine dependence is uncommon, but frequent use does commonly lead to tolerance.
text: While the long-term use of most dissociative drugs has not been investigated systematically, research shows that repeated use of PCP can lead to tolerance and the development of a substance use disorder that includes a withdrawal syndrome (including craving for the drug, headaches, and sweating) when drug use is stopped.