Assertion: human ngf | /r/HasProperty | major problems
Facets:
value: in actual application
type: OTHER
Source sentences:
text: Recombinant human NGF avoids some potential pathogenic risks, but there are still major problems in actual application: 1) as for maintaining the biological activity of NGF, like other proteins, the biological activity of NGF depends on the secondary and tertiary structures thereof, and thus it is particularly important to maintain its biological activity during preparation, purification, storage and administration; and 2) NGF may cause serious pain, which cannot be tolerated by some patients, during application, thereby partially limiting its use.