Assertion: classical monocyte | /r/CapableOf | differentiate into macrophage
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text: Our observation that only classical monocytes can differentiate into either DCs or macrophages points to the remarkable plasticity of this subset in comparison to the other monocyte subtypes and lends further support to the widely circulated but unproven hypothesis that the three monocyte subsets represent discrete stages on a spectrum of differentiation from classical to non-classical, with classical monocytes representing the least differentiated.