Assertion: reactive lymphocyte | /r/CapableOf | encounter self-antigens
Facets:
value: at very early stages of differentiation
type: TEMPORAL
value: at a time
type: TEMPORAL
Source sentences:
text: As originally conceived in this theory and also that of Lederberg (1219), this notion assumed that potentially self-reactive lymphocytes would encounter self-antigens at very early stages of differentiation at a time when the only inductive stimulus capable of being received by such cells was a tolerogenic signal.