Assertion: nucleic acid | /r/CapableOf | say ie solid support
Facets:
Source sentences:
text: (a) contacting a formally positively charged or potentially formally positively charged IE solid support with nucleic acids for a time sufficient for binding the nucleic acids to said IE solid support; (b) contacting the IE solid support, with the nucleic acid bound thereto, with at least one further compound different from the nucleic acid(s), dissolved in water at a pH≦6, which further compound is capable of binding to the remaining formally positive charge on the surface of the IE solid support and which optionally changes the charge density on the surface of the solid support, wherein the compound binds to the solid support; and (c) optionally washing the solid phase with the nucleic acid and the further compound(s) bound thereto; and (d) eluting the nucleic acids from the solid phase at mild pH and low salt conditions;
text: or: (e) contacting a formally positively charged or potentially formally positively charged positively charged IE solid support with nucleic acids for a time sufficient for binding the nucleic acids to said IE solid support; (f) contacting the IE solid support, with the nucleic acid bound thereto, with at least one further compound different from the nucleic acid(s), dissolved in water at a pH>6, which further compound is capable of binding to the remaining formally positive charge on the surface of the IE solid support and which optionally changes the charge density on the surface of the solid support, wherein the compound binds to the solid support; and (g) contacting the IE solid support, with the nucleic acid and the further compound(s) bound thereto, with a liquid comprising an overall pH≦6; and (h) optionally washing the solid phase with the nucleic acid and the further compound(s) bound thereto; and (i) eluting the nucleic acids from the solid phase at mild pH and low salt conditions;