Assertion: itch | /r/CapableOf | occur through the build-up of bile salts
Facets:
value: due to direct irritation of the skin
type: CAUSE
Source sentences:
text: Itching may occur due to direct irritation of the skin (such as with skin cancer or skin metastases), through the build-up of bile salts, or due to substances secreted by a tumor or by the body in response to a tumor.