Assertion: morphine | /r/CapableOf | case neurotoxicity
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Source sentences:
text: Morphine and hydromorphone both have 3-glucuronide metabolites that accumulate in renal failure and may case neurotoxicity, so these should be utilized with caution for chronic use in renal insufficiency (GFR <30 mL/min) due to the rapid accumulation of these metabolites.