Assertion: hyperkalemia's effect | /r/HasProperty | biphasic
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text: The effect of hyperkalemia on CV is biphasic, determined jointly by (1) the voltage difference between E m and the Na+ channel activation threshold (around −55 mV) and (2) the effect of E m on the steady-state inactivation of Na+ channels, which increases with depolarization so that fewer Na+ channels are available to be activated during the AP upstroke.