Assertion: lymphoma's cell | /r/CapableOf | bear recognized antigen
Facets:
value: on their surface membranes
type: LOCATION
Source sentences:
text: Chimeric antigen receptor T cells are genetically engineered to express: 1) an artificial T-cell receptor consisting of antigen-recognition and attached hinge domains expressed on their surface membranes; 2) a surface membrane-spanning domain; 3) an intracellular domain which, when the antigen-recognition domain binds its targeted antigen, activates signaling pathways that cause the T-cell to attack and kill cells that bear the recognized antigen on their surface membranes; and 4), in more recently devised second generation CAR-T strategies, an associated intracellular co-stimulating molecule (e.g. CD28 or 4‐1BB) which augments activation of the cell-killing signaling pathways.