Assertion: genotoxic impurity | /r/HasProperty | pgi
Facets:
Source sentences:
text: A potential genotoxic impurity (PGI) has been defined as an “Impurity that shows a Structural alert for genotoxicity but that has not been tested in an experimental test model.
text: Demonstration and documentation of strategies based on Quality-by-Design principles that establish control and assured elimination of potential genotoxic impurities (PGIs):
text: An impurity possessing a structural alert is often called a potentially genotoxic impurity (PGI) until further data (from biological or in-silico testing) confirm or deny its DNA-reactivity.