Assertion: classical monocyte | /r/HasProperty | prevalent
Facets:
value: in tumor-bearing mice
type: LOCATION
value: in humans
type: LOCATION
Source sentences:
text: Immunosuppressive classical monocytes, often termed monocytic myeloid-derived suppressor cells (M-MDSCs), are also prevalent in tumor-bearing mice and humans, as well as in inflammatory contexts such as sepsis and autoimmunity [reviewed in (4)]. They are characterized by their ability to suppress cytotoxic T cell and NK cell activation, promote anti-inflammatory and immunoregulatory responses (IL-10, regulatory T cells etc.), and support tumor progression and metastasis.