Assertion: opiate's use | /r/HasSubevent | physical dependence
Facets:
value: unfortunately
type: MANNER
Source sentences:
text: Unfortunately, even prescribed use of opiates can lead to physical dependence and addiction.
text: Chronic use of heroin leads to physical dependence, a state in which the body has adapted to the presence of the drug.
text: Prolonged use can lead to physical dependence.
text: Regular use can lead to drug tolerance or physical dependence.