Assertion: pharmaceutical impurity | /r/HasAspect | higher lipophilicity
Facets:
value: typically
type: DEGREE
Source sentences:
text: The general picture that emerges using either single or combined in-silico models is that systems using public-domain datasets (as is normally the case) perform adequately to predict the genotoxic potential of compounds in the same or similar “applicability domains” (ADs), but are deficient when challenged with pharmaceutical impurities, which typically have higher molecular weights, higher lipophilicity and more complex structures .