Assertion: hyperkalemia's effect | /r/HasProperty | determined by 1the voltage difference
Facets:
value: between e m
type: OTHER
value: jointly
type: MANNER
Source sentences:
text: The effect of hyperkalemia on CV is biphasic, determined jointly by (1) the voltage difference between E m and the Na+ channel activation threshold (around −55 mV) and (2) the effect of E m on the steady-state inactivation of Na+ channels, which increases with depolarization so that fewer Na+ channels are available to be activated during the AP upstroke.