Assertion: messenger | /r/CapableOf | initiate change
Facets:
value: within the cell
type: LOCATION
value: directly
type: MANNER
Source sentences:
text: Because peptide hormones and neurotransmitters typically are biochemically hydrophilic molecules, these first messengers may not physically cross the phospholipid bilayer to initiate changes within the cell directly—unlike steroid hormones, which usually do.