Assertion: lh's signal | /r/HasProperty | switched
Facets:
value: rapidly
type: MANNER
Source sentences:
text: Countering this postulate the following points should be noted: (1) the best and only true model to correctly inves tigate any luteinizing hormone hypothesis is the hypogonadotropic woman who may be totally luteinizing hormone deficient in contrast with down-regulated women where luteinizing hormone is not absent; (2) hCG is a hormone designed to support pregnancy not estro gen biosynthesis in the follicular phase; (3) hCG is normally not present in normal fertile women during this period; (4) luteinizing hormone over millions of years has evolved to produce a signal which can be rapidly switched on or off; (5) there are no data to support the notion that hCG represents the most important luteinizing hormone activity in vivo; (6) hCG has a slower plasma metabolic clearance and longer serum half-life than luteinizing hormone; (7) if hCG activity could really improve folliculogenesis, a higher oocyte yield with the use of HMG versus FSH-only drugs in IVF should be expected; certainly, this was never proved.