Assertion: loaded liposome | /r/CapableOf | enhance therapeutic effect of the drug
Facets:
value: significantly
type: MANNER
value: in comparison with free mxt
type: OTHER
Source sentences:
text: -1); from the antitumour effect studies that MXT loaded-liposomes enhanced the therapeutic effect of the drug significantly in comparison with free MXT; from the pharmacokinetic studies that MXT loaded-liposomes had longer circulation characteristics as compared with free MXT at the same dose; and from tissue distribution studies that MXT loaded-liposomes accumulated into tumour zones rather than normal tissues.
text: It was found that from the pharmacodynamic studies, that MXT loaded-liposomes inhibited tumour growth (at a dose of 1 to 4 mg kg); from the antitumour effect studies that MXT loaded-liposomes enhanced the therapeutic effect of the drug significantly in comparison with free MXT; from the pharmacokinetic studies that MXT loaded-liposomes had longer circulation characteristics as compared with free MXT at the same dose; and from tissue distribution studies that MXT loaded-liposomes accumulated into tumour zones rather than normal tissues.