Assertion: methadone | /r/ObjectUse | used with caution
Facets:
value: in such patients
type: OTHER
Source sentences:
text: In such patients, methadone must be used with caution, and only if it is deemed essential.21,22,23
text: Methadone hydrochloride for oral suspension should be used with caution in elderly and debilitated patients; patients who are known to be sensitive to central nervous system depressants, such as those with cardiovascular, pulmonary, renal, or hepatic disease; and in patients with comorbid conditions or concomitant medications which may predispose to dysrhythmia or reduced ventilatory drive.
text: In such patients, methadone must be used with caution, and only if it is deemed essential.