Assertion: local anesthetic's metabolite | /r/HasProperty | involved in addition
Facets:
value: to blockade of the nmda receptor
type: TRANSITIVE-OBJECT
Source sentences:
text: In addition to blockade of the NMDA receptor, the active metabolite of ketamine hydroxynorketamine, which does not interact importantly with the NMDA receptor but nonetheless indirectly activates AMPA receptors similarly, may also or alternatively be involved in the rapid-onset antidepressant effects of ketamine.