Assertion: monocyte's role | /r/HasProperty | important
Facets:
value: in chronic inflammation
type: OTHER
value: in preventing intestinal tissue necrosis
type: TRANSITIVE-OBJECT
Source sentences:
text: As macrophages, monocytes play an important role of eliminating foreign material, tumorous cells and microorganisms through a process known as phagocytosis.
text: Thus, the role of macrophages in inducing apoptosis and clearing neutrophils from inflamed gut tissues are essential in preventing intestinal tissue necrosis and pathology.
text: This role is important in chronic inflammation, as the early stages of inflammation are dominated by neutrophils, which are ingested by macrophages if they come of age (see CD31 for a description of this process).
text: Monocytes play an important role in immune defense, inflammation, and homeostasis by sensing their local environment, clearing pathogens and dead cells, and initiating adaptive immunity, as well as providing a progenitor pool that contributes to inflammatory DCs and replenishes some tissue macrophages [ 1 – 4 ].
text: Monocytes have an essential role in antimicrobial immune defence and promote tissue healing but, like a double-edged sword, they also contribute to tissue destruction during some infections and inflammatory diseases.