Assertion: lacrimal gland | /r/HasProperty | dc
Facets:
Source sentences:
text: Recently, studies on breast carcinoma and SDC have revealed frequent mutations in several actionable cancer‐related genes, making us hypothesize that these findings could apply to lacrimal gland DC as well (Dogan et al.
text: No obvious CD30 expression in lacrimal gland (C) or conjunctiva (D) disordered by GVHD.
text: However, 8/16 (50%) presenting with M0 disease and available follow‐up developed distant metastases and 9/22 (40.9%) died of their disease illustrating the aggressive nature of lacrimal gland DC.
text: Interestingly, increased frequency of PTEN deletion and decreased PTEN expression have been detected in HER2‐ amplified SDC, suggestive of two separate mechanisms of PI3K activation that might be the case in lacrimal gland DC as well (i.e. HER2‐mediated
text: In conclusion, we present the first insight into the genetics of lacrimal gland DC.
text: The immunohistochemical profile and mutational pattern of DC strongly resemble SDC and a subset of breast carcinomas, and advances in treatment of these far more frequent malignancies could result in acceleration of available treatments in patients with lacrimal gland DC.