Assertion: hydrogen peroxide's effect | /r/HasProperty | mediated by result
Facets:
value: in the activation of rac1
type: TEMPORAL
Source sentences:
text: Phosphatidylinositol trisphosphate (PIP 3 ), a product of PI3K, is thought to recruit guanine nucleotide exchange factors for the small GTP-binding protein Rac1 to the cell membrane; this effect is mediated by interaction of the pleckstrin homology domains of these proteins with PIP 3 and results in the activation of Rac1.