Assertion: nucleic acid | /r/CapableOf | charge changing compound
Facets:
value: like an organic acid
type: OTHER
value: optionally
type: MANNER
Source sentences:
text: Without being bound to this theory it is assumed that a main feature of the present invention, i.e. the possibility of low salt release of nucleic acids bound to an IE solid support, is obtained by the following 2 key factors: (1) contacting the IE solid support having the nucleic acid bound thereto with a liquid (solution) of a dissolved shielding and optionally charge changing compound like for example an organic acid, and (2) contacting the IE solid support having the nucleic acid and the shielding/charge changing compound bound thereto with a liquid (solution) having a pH≦6 before eluting the nucleic acid from the IE solid support.