Assertion: methylphenidate | /r/HasProperty | metabolized by de-esterification
Facets:
value: primarily
type: DEGREE
value: in humans
type: OTHER
value: to acetic acid
type: TRANSITIVE-OBJECT
value: to ppaa
type: TRANSITIVE-OBJECT
Source sentences:
text: In humans, methylphenidate is metabolized primarily by de-esterification to PPAA, which has little or no pharmacologic activity.
text: In humans, methylphenidate is metabolised primarily by de-esterification to α-phenyl-piperidine acetic acid (PPAA) which has little or no pharmacologic activity.
text: Methylphenidate is metabolized primarily by de-esterification to alpha-phenyl-piperidine acetic acid (Ritalinic acid), which has little or no pharmacologic activity.
text: Methylphenidate is metabolized primarily by de-esterification to alpha-phenyl-piperidine acetic acid (ritalinic acid), which has little or no pharmacologic activity.
text: In humans, methylphenidate is metabolized primarily by de-esterification to PPAA, which has little or no pharmacologic activity.
text: In humans, methylphenidate is metabolized primarily by de-esterification to α-phenyl-piperidine acetic acid (PPAA).
text: In humans, methylphenidate is metabolized primarily by de-esterification to PPAA, which has little or no pharmacologic activity.
text: In humans, methylphenidate is metabolised primarily by de-esterification to α-phenyl-piperidine acetic acid (PPAA) which has little or no pharmacologic activity.
text: In humans, methylphenidate is metabolised primarily by de-esterification to alpha-phenyl-piperidine acetic acid (PPA, approximately 50 fold the level of the unchanged substance) which has little or no pharmacologic activity.