Assertion: naproxen's metabolite | /r/HasProperty | excreted by the kidney
Facets:
value: substantially
type: DEGREE
value: given that naproxen
type: OTHER
value: primarily
type: DEGREE
Source sentences:
text: Given that Naproxen, its metabolites and conjugates are primarily excreted by the kidney, the potential exists for Naproxen metabolites to accumulate in the presence of renal insufficiency.
text: Naproxen and its metabolites are known to be substantially excreted by the kidney, and the risk of adverse reactions to this drug may be greater in patients with impaired renal function.