Assertion: ligand's group | /r/CapableOf | play greater role
Facets:
value: in ligand preorganization
type: OTHER
value: through intramolecular hydrogen bonding
type: MANNER
Source sentences:
text: Other groups, like the ortho-methoxyphenyl group, can be important in specific cases, but are thought to play a greater role in ligand preorganization through intramolecular hydrogen bonding, rather than through direct interaction with binding site residue.