Assertion: helical filament | /r/HasProperty | phf
Facets:
Source sentences:
text: The use of these NPs to label native paired helical filaments (PHFs) from the postmortem brain of a patient with Alzheimer’s disease, as well as amyloid fibrils extracted from the heart tissue of a patient suffering from systemic amyloid light-chain amyloidosis, revealed a high degree of homogeneity across the fibrils derived from human tissue in comparison with fibrils aggregated in vitro.
text: In particular,F-MK6240,F-RO6958948, andF-PI26208 have been shown to bind to NFTs and paired helical filaments (PHFs) and have been clinically tested in tauopathies.