Assertion: endosteum's cell | /r/CapableOf | induce increased
Facets:
Source sentences:
text: 30 SDF-1/CXCR4 expression is regulated by hypoxia inducible factor-1 (HIF-1), and since the BM is partially hypoxic,27 this pair is functionally expressed by many cell types including immature and maturing hematopoietic cells, stromal cells lining the stem cell rich endosteum region, and human Stro1+ mesenchymal progenitors.20,31 TBI induces increased SDF-1 and SCF secretion within 24 to 48 hours in the murine BM and spleen.5,20,21 SDF-1 secreted to the circulation from the injured murine liver can functionally pass the endothelium barrier in a CXCR4-dependent manner into the BM and recruit hematopoietic progenitors to the circulation.13