Assertion: phenytoin | /r/Causes | significant decreases
Facets:
value: clinically
type: MANNER
value: in concentrations of drugs
type: OTHER
Source sentences:
text: For example, clinicians are aware that phenytoin is a potent inducer of CYP2D6 and CYP3A4 and can cause clinically significant decreases in concentrations of drugs metabolized by these isoenzymes.1–3