Assertion: slow glycolysis | /r/CapableOf | help prevent acidosis
Facets:
value: due to excess lactate
type: CAUSE
Source sentences:
text: : Phosphofructokinase 1 is inhibited by low pH. The lactate (ionized lactic acid; lactate + H+ at physiological pH; pKa of lactic acid = 3.85, physiological pH = 7.4) that is formed under anaerobic conditions contributes to lower pH. Therefore, slowing glycolysis at the committed step slows lactate production and helps prevent acidosis (lactic acidosis) due to excess lactate (lactic acid).