Assertion: fibril's affinity | /r/HasProperty | extracted
Facets:
value: from nmr titrations attenuation profiles
type: OTHER
Source sentences:
text: A fitted global affinity (K D ) of 67 ± 17 nM and a fitted off-rate of 0.015 ± 0.006 s−1 could be extracted.
text: In general, affinities (K D ) can be extracted from NMR titrations attenuation profiles by fitting the concentration dependency of the attenuation with a single exponential decay for each resolved peak (corresponding to one assigned residue in a two-state binding model, i.e., unbound and membrane attached).