Assertion: erythromycin's effect | /r/HasProperty | depend on serum concentration
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text: Prolongation of the QT interval and development of ventricular arrhythmias, including atypical ventricular tachycardia (torsades de pointes), have been reported rarely with oral and IV erythromycin; limited data suggest that these adverse effects may depend on serum concentration and/or rate of infusion of the drug.260 305 306 307 308 360 362 376 481 Decreasing IV infusion rate may reduce the risk of cardiac toxicity, but may not eliminate the risk and discontinuance of the drug may be necessary.360 362