Assertion: erythromycin's effect | /r/HasProperty | 3 to 6 months
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text: Acne, moderate to severe; treatment: Children and Adolescents: Oral: 250 to 500 mg 1 to 2 times daily in conjunction with topical therapy (eg, benzoyl peroxide); maximum daily dose: 50 mg/kg/day; duration of 4 to 8 weeks of therapy usually necessary to evaluate initial clinical response with a longer duration for a maximum effect (3 to 6 months); resistance problematic with therapy, use typically reserved for patients <8 years who cannot receive tetracycline derivatives (Eichenfield 2013)