Assertion: nonsteroidal estrogen | /r/CapableOf | fall following the discovery of toxicities
Facets:
value: out of favor
type: OTHER
value: gradually
type: MANNER
Source sentences:
text: Although nonsteroidal estrogens formerly had an important place in medicine, they have gradually fallen out of favor following the discovery of toxicities associated with high-dose DES starting in the early 1970s, and are now almost never used.