Assertion: glucocorticoid's effect | /r/HasProperty | pronounced in first 3 to 6 months of use
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text: However, a major adverse effect of this pharmacologic treatment is significant bone loss, which is most pronounced in the first 3 to 6 months of use and has been reported with daily doses as low as 2.5 to 7.5 mg of prednisone or its equivalent.1,2