Assertion: fibril | /r/MadeOf | three model hexapeptides
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text: An investigation of the influence of the orientation, distance and number of laterally stacked intermolecular β-sheets on the calculated spectra of fibrils formed by three model hexapeptides (GGVVIA, NNQQNY and SNQNNF, see Supporting Information) shows that these effects are not unique for the in silico constructed αS-like fibrils, but that generally for in-register amyloid fibrils (I) a high-frequency peak appears when they are composed of hydrogen-bonded β-sheets that are closely packed, and (II) a low-frequency shoulder appears when they are composed of hydrogen-bonded β-sheets stacked in a parallel fashion (in the direction perpendicular to the fibril axis).