Assertion: hormone estrogen | /r/HasProperty | inactivated in the liver
Facets:
value: efficiently
type: MANNER
value: at high dosages
type: TEMPORAL
value: at high circulating levels
type: OTHER
value: unlike synthetic estrogens
type: OTHER
value: as in pregnancy
type: TEMPORAL
Source sentences:
text: Unlike synthetic estrogens, bioidentical estrogens are efficiently inactivated in the liver even at high dosages or high circulating levels, as in pregnancy, although changes in hepatic protein production can still occur.