Assertion: glucocorticoid | /r/CapableOf | impair the uptake
Facets:
value: in β-cells
type: OTHER
value: through genomic actions
type: MANNER
Source sentences:
text: Glucocorticoids may also impair the uptake and the metabolism of glucose in β-cells through genomic actions (i.e., modulation of gene expression by nuclear glucocorticoid receptor) which lead to a decrease in the efficacy of cytoplasmic Ca2+ on the exocytotic process of insulin secretory vehicles .