Assertion: histidine's effect | /r/HasProperty | due
Facets:
value: to the axial mutation
type: CAUSE
value: to the accompanying porphyrin tilt
type: CAUSE
value: to the presence of mc
type: CAUSE
value: to reduced translation
type: CAUSE
Source sentences:
text: The authors believed that the effect was due to the role of histidine as a precursor to histamine, a seizure inhibitor .
text: This effect is due to an inherent structural instability of non-methylated actin monomers (and not the loss of any actin-interacting protein), which the authors detected using a thermal stability assay.
text: In contrast, the T213A/C317H structure shows a much greater distortion within the I helix (RMSD of 3.2 Å relative to wild type using only backbone atoms), which strongly suggests that the observed effect on the I helix is due to the axial mutation and the accompanying porphyrin tilt.
text: In contrast, the T213A/C317H structure shows a much greater distortion within the I helix (RMSD of 3.2 Å relative to wild type using only backbone atoms), which strongly suggests that the observed effect on the I helix is due to the axial mutation and the accompanying porphyrin tilt.
text: To validate that the effect was due to reduced translation and not to a difference in mRNA levels, RT-PCR was performed with oligos hybridising to the cbrX and cbrA coding regions.
text: The apparent effect from the combination of the enzymes, in fact, was due to the presence of MC, as shown by its isolated inclusion.