Assertion: enzyme's substrate | /r/HasProperty | bound
Facets:
value: the more tightly
type: MANNER
value: lower the km
type: OTHER
value: completely
type: DEGREE
Source sentences:
text: The active site continues to change until the substrate is completely bound, at which point the final shape and charge distribution is determined.
text: -The lower the Km, the more tightly the substrate is bound.