Assertion: estrogen's effect | /r/HasProperty | mediated through its interactions
Facets:
value: with non-nuclear prs
type: OTHER
value: predominantly
type: DEGREE
Source sentences:
text: The effects of progesterone as a neurosteroid are mediated predominantly through its interactions with non-nuclear PRs, namely the mPRs and PGRMC1, as well as certain other receptors, such as the σ 1 and nACh receptors.[citation needed]