Assertion: tissue engineered heart valve | /r/HasProperty | destined for human implantation
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Source sentences:
text: Specific hurdles include optimization and scale up of processing components and conditions in vitro to generate a highly functional and durable valve in vivo, selection and validation of suitable animal models, development of guidelines for characterization, and assurance of the quality of an in vitro fabricated tissue-engineered heart valve destined for human implantation, validation of the hypothesis that tissue evolution in vivo can be predicted and measured, and the development of strategies to understand, monitor, and potentially control patient variability in tissue remodeling in vivo.