Assertion: hemophilia's factor | /r/HasProperty | viii
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Source sentences:
text: Acquired hemophilia is usually caused by the development of antibodies to factor VIII (the body’s immune system destroys its own naturally produced factor VIII).
text: TF is released from the damaged cells and is thought to be a lipoprotein complex that acts as a cell surface receptor for factor VII, with its resultant activation.
text: Thus, males can have a disease like hemophilia if they inherit an affected X chromosome that has a mutation in either the factor VIII or factor IX gene.
text: The goal of treatment is to give you the factor VIII your body doesn't make.
text: It bridges the gap in the clotting factors left by the missing factor VIII.
text: It works by bridging the gap in the clotting factors left by the missing factor VIII.
text: Hemophilia is caused by mutations in either the factor VIII or factor IX genes on the X chromosome.
text: , , Assembled databases that contain more than 2,000 factor VIII (factor 8) gene mutations and over 1,000 factor IX (factor 9) gene mutations ( CHAMP and
text: People with hemophilia have low amounts of either factor VIII (factor 8) or factor IX (factor 9) in their blood.
text: As such, one copy of the abnormal factor VIII or factor IX gene results in hemophilia in males, and a carrier state in females.
text: The factor VIII or factor IX levels are abnormally low
text: There is a deficiency of either factor VIII which causes hemophilia A or factor IX which gives rise to hemophilia B Types Type 1 –
text: This means that his body, his immune system, fights off the medicine – the infused factor VIII.
text: Hemophilia is a bleeding disorder usually caused by defects (mutations) in the genes that code for the blood-clotting factors VIII, IX or XI.
text: The most common type of hemophilia, hemophilia A, is caused by a lack of a clotting factor called factor 8 (VIII).
text: Factor 8 (VIII) is a specialized protein called a coagulation, or clotting, factor.
text: Without von Willebrand factor attached, the factor VIII (8) is destroyed quickly.
text: The human factor VIII (8) (or IX ) gene is isolated through genetic engineering.
text: The disease is an X-linked recessive bleeding disorder caused by defects in the clotting cascade enzyme factor VIII.
text: Hemophilia is a genetic disorder caused by a change in the DNA of either the factor VIII or factor IX gene.
text: Gene therapy using adenovirus-associated delivery of either the factor VIII or IX gene is also in clinical trials for the treatment of hemophilia A or B (8).
text: Although much remains to be studied before such treatment can be offered to patients, there have been a number of studies done in animals such as mice and dogs in which a factor VIII or IX gene has been inserted and has produced the proper blood product for periods that exceed one year.
text: It is important to mention that a person suffering from hemophilia can lack only either of the factors - VIII or factor IX.
text: Obizur is a recombinant factor VIII derived from pigs that can be used to treat patients with acquired hemophilia A.
text: For example, a child with mild hemophilia may have up to 49% of the normal factor VIII in his body, while a child with severe hemophilia has very little factor VIII.
text: If a low factor VIII level is obtained, PTT mixing studies should be performed to determine if a low factor VIII is a result of a simple deficiency of the factor or the presence of a neutralizing factor VIII inhibitor.
text: A. A PTT mixing study and, if equivocal, a Bethesda unit assay determines whether the low factor VIII is a simple deficiency or the result of a factor VIII inhibitor.
text: About 30% recombination was found between the factor VIII and IX loci.
text: Standard half-life products is factor which lasts in the body for the same amount of time as the natural factor VIII or factor IX
text: While factor VIII infusions are generally effective, there is a 20 percent chance a patient’s body will reject the factor VIII after receiving treatment.
text: In these cases, the patient may need to find another source for the factor VIII or try a different dosage amount.
text: Factor 8 (VIII) for hemophilia A
text: In both cases, the factor VIII or IX protein is nearly identical to the protein which is lacking in the blood of hemophiliacs.
text: For people with mild and in some instances moderate hemophilia, DDAVP can work to increase their own factor VIII (
text: (7) APCC is made from human plasma and includes a concoction of other clotting factors, such as factors 7 (VII), 9 (IX), and 10 (X).