Assertion: dermal fibroblast | /r/CapableOf | alter their transcriptome
Facets:
value: in culture
type: LOCATION
value: dramatically
type: MANNER
Source sentences:
text: Thus, dermal fibroblasts dramatically alter their transcriptome in culture and do not retain their corresponding in vivo age, making it difficult to reach any conclusion about their propensity to differentiate along the adipogenic lineage using in vitro experiments and raising caution about using 2D cell culture systems to study aging.