Assertion: l histidine | /r/HasProperty | a racemic mixture
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Source sentences:
text: The invention also provides a method of providing nutrition to a mammal in need thereof, which method comprises administering to said mammal a composition comprising: (a) an effective amount of a cyto-protective agent wherein said cyto-protective agent is selected from the group consisting of at least one of D-histidine, L-histidine, a racemic mixture thereof, a non-racemic mixture thereof, and nutriceutically acceptable salts thereof; and (b) an effective amount of at least one of a phytonutrient having antioxidant activity wherein said phytonutrient having antioxidant activity is selected from the group consisting of carotenoids, flavonoids, tocopherols, ascorbates and mixtures thereof.
text: The instant invention is further directed to a controlled release formulation in tablet form for once-daily oral administration of about 500-1500 mg of at least one of D-histidine, L-histidine, a racemic mixture thereof, a non-racemic mixture thereof, and nutriceutically acceptable salts thereof, which tablet comprises a homogeneous matrix comprising: about 3-12 weight percent of hydroxypropyl mehylcellulose having a number average molecular weight in the range of from about 50,000 to about 150,000; about 75-97 weight percent of at least one of D-histidine, L-histidine, a racemic mixture thereof, a non-racemic mixture thereof, and nutriceutically acceptable salts thereof in an amount effective for once daily oral administration; and about 0.05 to about 4 weight percent of a pharmaceutically acceptable lubricating agent.
text: The instant invention is further directed to a controlled release formulation in tablet form for once-daily oral administration of about 500-1500 mg of at least one of D-histidine, L-histidine, a racemic mixture thereof, a non-racemic mixture thereof, and nutriceutically acceptable salts thereof, which tablet comprises a homogeneous matrix comprising: about 3-12 weight percent of hydroxypropyl mehylcellulose having a number average molecular weight in the range of from about 50,000 to about 150,000; about 75-97 weight percent of at least one of D-histidine, L-histidine, a racemic mixture thereof, a non-racemic mixture thereof, and nutriceutically acceptable salts thereof in an amount effective for once daily oral administration; and about 0.05 to about 4 weight percent of a pharmaceutically acceptable lubricating agent.
text: The present invention also provides a new controlled release oral tablet for once a day administration of 500-1500 mg of D-histidine, L-histidine, a racemic mixture thereof, a non-racemic mixture thereof, and nutriceutically acceptable salts thereof, which tablet comprises a homogeneous matrix comprising: about 3-12 weight percent of hydroxypropylmethylcellulose having a number average molecular weight in the range of from about 50,000 to about 150,000; about 75-97 weight percent of D-histidine, L-histidine, a racemic mixture thereof, a non-racemic mixture thereof, and nutriceutically acceptable salts thereof, in an amount effective for once daily oral administration; and about 0.05 to about 4 weight percent of a pharmaceutically acceptable lubricating agent.
text: The present invention also provides a new controlled release oral tablet for once a day administration of 500-1500 mg of D-histidine, L-histidine, a racemic mixture thereof, a non-racemic mixture thereof, and nutriceutically acceptable salts thereof, which tablet comprises a homogeneous matrix comprising: about 3-12 weight percent of hydroxypropylmethylcellulose having a number average molecular weight in the range of from about 50,000 to about 150,000; about 75-97 weight percent of D-histidine, L-histidine, a racemic mixture thereof, a non-racemic mixture thereof, and nutriceutically acceptable salts thereof, in an amount effective for once daily oral administration; and about 0.05 to about 4 weight percent of a pharmaceutically acceptable lubricating agent.
text: The term matrix, as used herein, refers to a uniform mixture of D-histidine, L-histidine, a racemic mixture thereof, a non-racemic mixture thereof, and nutriceutically acceptable salts thereof, hydroxypropyl methylcellulose, a lubricating agent, and other optionally included excipients.
text: In accordance with the present invention, the amount of D-histidine, L-histidine, a racemic mixture thereof, a non-racemic mixture thereof, and nutriceutically acceptable salts thereof, that is incorporated in a tablet may range between about 500 and about 1500 mg.
text: Generally, D-histidine, L-histidine, a racemic mixture thereof, a non-racemic mixture thereof, and nutriceutically acceptable salts thereof, are administered at levels of 500, 750, 1000 or 1500 mg/day.