Assertion: epidermis's type | /r/HasProperty | i ifns
Facets:
Source sentences:
text: Activated pDCs lose their typical plasmacytoid morphology and the ability to produce type I IFNs, and differentiate into cells with a dendritic morphology expressing MHC and T cell costimulatory molecules, although they are less efficient than cDCs in priming naïve T cell.
text: The development of skin lesions in CLE patients is induced by pDC-derived type I IFN (Blomberg et al., 2001).
text: Furthermore, targeting pDCs using anti-BDCA2 antibodies, that block their ability to produce type I IFNs, equally inhibited the activation of autoreactive T cells and the development of skin lesions.