Assertion: l histidine | /r/CapableOf | react with pge
Facets:
value: chemically
type: MANNER
Source sentences:
text: l-Histidine and imidazole reacted with PGE 2 in vitro in cell-free mixtures incubated at 37°C and pH 7.0 under an atmosphere of N 2 with the formation of PGE 2 –imidazole and PGE 2 –histidine covalent adducts.
text: More specifically, unpublished studies of one of the present coinventors reveal that L-histidine chemically reacts with PGE 2 thereby disabling or inactivating the prostaglandin in its role in the inflammatory cascade (e.g., PGE 2 's stimulatory effect on adenylate cyclase).