Assertion: hemolysis's effect | /r/RelatedTo | excessive free hb
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Source sentences:
text: Adverse clinical effects associated with excessive free Hb can be attributed to several specific structural and biochemical properties of the Hb molecule and are caused by the following 4 mutually interacting mechanisms: (1) extravascular translocation of Hb, which is a principal requirement that Hb and hemin can unleash their adverse reactivity in tissues; (2) nitric oxide and oxidative reactions; (3) release of free hemin; and (4) molecular-signaling effects of hemin.