Assertion: ecstasy's use | /r/HasSubevent | physical dependence
Facets:
value: regardless of the knowledge
type: OTHER
Source sentences:
text: The National Institute on Drug Abuse (NIDA) reports that ecstasy use can lead to tolerance, physical dependence, withdrawal symptoms, and continued use regardless of the knowledge that doing so will have negative physiological or physical consequences.
text: Chronic use of some of these products may lead to physical dependence or the development of a substance use disorder.
text: NIDA reports that chronic use of ecstasy (MDMA) may lead to physical dependence; however, numerous research studies and professional sources report that while tolerance to MDMA does develop, chronic use of the drug does not result in the development of a significant withdrawal syndrome.