Assertion: activated eosinophil | /r/HasAspect | the capacity
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text: Regardless of the mechanism of disease induction, activated eosinophils have the capacity to participate in multiple aspects of disease, including the promotion of proinflammatory damage (through the secretion of cytotoxic granule proteins), tissue remodeling (through the secretion of pleiotropic cytokines such as TGF), sustenance of the immune response (by activating T cells via antigen presentation and by regulating T-cell cytokine production), and causing end-organ dysfunction (e.g., antagonism of muscarinic receptors or elicitation of cardiomyopathy).