Assertion: eosinophil's granule | /r/CapableOf | undergo depletion of their contents9
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text: The presence of membranous domains within specific granules was confirmed by immunonanogold EM, a technique that provides precise epitope preservation,69 which revealed pools of CD63 within granules undergoing depletion of their contents9, 70 and by electron tomographic analyses, which enabled 3D visualization of granules in high resolution.70 Application of electron tomography brought a new view of specific granules as organelles with membranous subcompartments organized as an aggregate of flattened tubular networks and tubules with interconnections in some planes as well as connections with the granule limiting membrane.70