Assertion: fibril's end | /r/HasProperty | rate-limiting
Facets:
value: no longer
type: TEMPORAL
Source sentences:
text: Considering now the complementary case of systems with a fixed initial seed concentration and varying initial monomer concentration, Eq. 5 shows that, ifis independent of the monomer concentration, the theory predicts that the initial gradient will be proportional to the total monomer concentration; indeed, the fibril elongation rate is given asAt high monomer concentrations, however, diffusion of monomers to the fibril ends is no longer rate-limiting; instead, the structural reorganization of the polypeptide chain subsequent to its initial attachment to a fibril end takes over this role.