Assertion: mitochondrial fusion | /r/CapableOf | use mfn1 and mfn2 knock-out mice
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text: Using Mfn1 and Mfn2 knock-out mice, which die in utero at midgestation due to a placental deficiency, mitochondrial fusion was shown not to be essential for cell survival in vitro, but necessary for embryonic development and cell survival throughout later stages of development.