Assertion: enhanced glycolysis | /r/HasProperty | due
Facets:
value: to an impairment of mitochondrial function
type: CAUSE
Source sentences:
text: Enhanced glycolysis in certain cancers is due to an impairment of mitochondrial function ( , ), including decreased expression of mitochondrial oxidative enzymes and transporters, truncated TCA cycle, a lowering in the amount of mitochondria per cell and defective respiratory chain, an increased amount in the natural inhibitors of the mitochondrial ATP synthase and a higher sensitivity of mtDNA to oxidative stress ( , ).