Assertion: ketoconazole foam | /r/HasProperty | mrhd
Facets:
Source sentences:
text: Assuming equivalent systemic absorption of topical and oral ketoconazole doses and a Ketoconazole Foam, 2% maximum recommended human dose (MRHD) of 8 grams (equivalent to 160 mg ketoconazole), embryotoxic effects were observed at 0.8 to 2.4 times the MRHD and developmental effects were observed at 4.8 times the MRHD [see Data].
text: The animal multiples of human exposure calculations are based on body surface area (BSA) comparisons of oral doses administered to animals and a Ketoconazole Foam, 2% maximum recommended human dose (MRHD) of 8 grams (equivalent to 2.67 mg ketoconazole/kg/day for a 60 kg individual or 98.8 mg ketoconazole/m2/day).