Assertion: estrogen | /r/HasAspect | antigonadotropic effects
Facets:
value: via activation of the er
type: MANNER
value: at sufficiently high concentrations
type: OTHER
Source sentences:
text: Estrogens also have antigonadotropic effects and at sufficiently high dosages can strongly suppress sex hormone production.
text: Estrogens have antigonadotropic effects at sufficiently high concentrations via activation of the ER and hence can suppress the hypothalamic–pituitary–gonadal axis.