Assertion: frailty | /r/CapableOf | represent global risk state
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text: multiple domains.17,18 This definition reflects the fact that frailty represents a global risk state (eg, it is not solely a risk factor for single organ complications), that frailty status can be impacted both by processes of aging (such as cellular and tissue breakdown) and disease-specific processes (eg, proinflammatory features of diabetes, or decreased cardiac function in coronary artery disease) and that frailty is a multidimensional entity that cannot be quantified by a single measurement.