Assertion: fungus's host | /r/HasProperty | worst outcome
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Source sentences:
text: Used Histoplasmosis Acute pulmonary histoplasmosis with hypoxia; prolonged moderate symptoms for more than 1 month; disseminated disease; immunosuppressed host Mortality rate for untreated disseminated disease at 80%; reduced to 25% with treatment Significant hemoptysis; recurrent pneumonia; repair of bronchopleural fistula Corticosteroids in severe hypoxia or ARDS Anti-inflammatory agents to treat rheumatologic syndromes Amphotericin B induces rapid response in patients who are severely ill or immunocompromised Azoles/triazoles in patients with milder illness Coccidioidomycosis Disseminated disease; chronic pulmonary disease; acute pulmonary infection with hypoxia or protracted morbidity (>1-2 mo); immunosuppressed host (worst outcome, 70% mortality) Surgical debridement or resection of infective tissue often necessary adjunct to antifungal treatment Anti-inflammatory agents for rheumatologic syndromes Amphotericin B effective in more than 90% of cases; first choice in severe cases or immunocompromised Fluconazole/itraconazole first choice in mild to moderate infection (or after improvement)