Assertion: glucocorticoid's effect | /r/CapableOf | target gene
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text: Compared with WT GR, which was detected at every site examined, the S425G mutation reduced GR occupancy at specific NF-κB target genes (IL6 and ICAM1, but not IL8) and one of the three GC-induced genes (FKBP5 but not GILZ or SGK1), confirming that this mutation has gene-specific effects on GR’s DNA-binding ability and recruitment to target genes (Fig.