Assertion: phenytoin | /r/HasProperty | hydroxylated in the liver
Facets:
value: by an enzyme system
type: OTHER
Source sentences:
text: Because phenytoin is hydroxylated in the liver by an enzyme system which is saturable at high serum levels, small incremental doses may increase the half-life and produce very substantial increases in serum levels, when these are in the upper range.
text: Because phenytoin is hydroxylated in the liver by an enzyme system which is saturable at high serum levels, small incremental doses may increase the half-life and produce very substantial increases in serum levels, when these are in the upper range.
text: Because phenytoin is hydroxylated in the liver by a cytochrome system which is saturable at high plasma levels, additional phenytoin doses may increase the half-life and produce very substantial increases in serum levels when these are in or above the upper therapeutic range.
text: Because phenytoin is hydroxylated in the liver by a cytochrome system which is saturable at high plasma levels, additional phenytoin doses may increase the half-life and produce very substantial increases in serum levels when these are in or above the upper therapeutic range.