Assertion: choline | /r/AtLocation | high demand
Facets:
value: as a substrate
type: MANNER
value: during pregnancy
type: TEMPORAL
Source sentences:
text: Choline is in high demand during pregnancy as a substrate for building cellular membranes, (rapid fetal and mother tissue expansion), increased need for one-carbon moieties (a substrate for addition of methylation to DNA and other functions), raising choline stores in fetal and placental tissues, and for increased production of lipoproteins (proteins containing "fat" portions).