Assertion: chloroquine | /r/HasProperty | toxic
Facets:
value: for human use
type: PURPOSE
value: extremely
type: DEGREE
value: with a terrible side effect profile
type: OTHER
value: to algae
type: TRANSITIVE-OBJECT
value: to many invertebrates
type: TRANSITIVE-OBJECT
value: at doses
type: OTHER
value: to bacteria
type: TRANSITIVE-OBJECT
value: at levels
type: OTHER
Source sentences:
text: Chloroquine has a relatively narrow therapeutic index and it can be toxic at levels not much higher than those used for treatment—which raises the risk of inadvertent overdose.
text: "Chloroquine is an extremely toxic drug with a terrible side effect profile.
text: It was ignored for a decade, because it was considered too toxic for human use.
text: It was first thought to be too toxic for any practical use, but decades later, it was shown in clinical trials to have significant value as an anti-malarial drug.
text: At doses typically used to treat fish diseases, chloroquine is also toxic to many invertebrates, algae and bacteria.
text: Bayer, the company whose scientists discovered the compound, conducted testing in animals and concluded that chloroquine was so toxic that it could not be practically or safely administered to humans.
text: Chloroquine can be extremely toxic when not administered under the supervision of a physician; doses as low as two grams can be fatal, and it has a variety of severe side effects.
text: "Chloroquine is an extremely toxic drug with a terrible side effect profile.
text: Chloroquine was discovered in 1934 by Hans Andersag but was initially ignored for a decade because it was considered too toxic for human use.