Assertion: fibrillar collagen | /r/HasProperty | required in vascular system
Facets:
Source sentences:
text: Most commonly, EDS is linked to the mutations of COL1A1, COL1A2, COL3A1, COL5A1, COL5A2, which affects collagen type I, III, and V. These mutations all affect fibrillar collagen required in the skin, tendons, and vascular system .