Assertion: genetic correlation | /r/ObjectUse | used in gwases
Facets:
value: by using polygenic scores
type: MANNER
Source sentences:
text: Genetic correlations can be used in GWASes by using polygenic scores or genome-wide hits for one (often more easily measured) trait to increase the prior probability of variants for a second trait; for example, since intelligence and years of education are highly genetically correlated, a GWAS for education will inherently also be a GWAS for intelligence and be able to predict variance in intelligence as well and the strongest SNP candidates can be used to increase the statistical power of a smaller GWAS, a combined analysis on the latent trait done where each measured genetically-correlated trait