Assertion: codeine | /r/HasProperty | converted via first pass metabolism
Facets:
value: into morphine
type: OTHER
value: by the cytochrome p450 enzyme
type: OTHER
Source sentences:
text: Codeine is not itself centrally active, and must first be converted via first pass metabolism into morphine by the cytochrome P450 enzyme CYP2D6 (as such, it is a prodrug for morphine).