Assertion: comfrey's alkaloid | /r/HasProperty | toxic
Facets:
value: to the liver
type: TRANSITIVE-OBJECT
value: potentially
type: DEGREE
value: as another
type: OTHER
value: highly
type: DEGREE
Source sentences:
text: However, studies have shown that comfrey is not safe to be taken for internal use as the plant contains pyrrolizidine alkaloids, which are toxic to the liver.
text: Comfrey contains highly toxic pyrrolizidine alkaloids, which is why its oral use is unsafe.
text: Comfrey contains pyrrolizidine alkaloids which are toxic compounds readily absorbed via the stomach or skin, and have potential to increase the risk of fatal liver toxicity.
text: This caution is due to the dangers of the pyrrolizidine alkaloids that are toxic to the liver and may have cancer-causing effects, even in small amounts.
text: It is unclear as to whether the alkaloids are toxic in the context of the whole plant, since they are only present in minute amounts and are often completely absent from samples of dried aerial parts.
text: Although comfrey can heal, it can also harm due to pyrroloxidine alkaloids (PA), which can be toxic to the liver.
text: One alkaloid can be six or more times as toxic as another, and some are not toxic at all.
text: While comfrey is made up of a multitude of healing substances, including calcium, tannins, rosmarinic acid, mucilage and vitamins A, C and B12, it also contains - in its fresh, young leaves and roots - a high level of pyrrolizidine alkaloids, which are toxic to the liver.
text: Children under 12 years: Comfrey should not be given to children under 12 years because it contains toxic alkaloids.
text: Further, comfrey contains potentially toxic pyrrolizidine alkaloids, but absorption is significantly lower through the skin compared with if given orally.
text: Further, comfrey contains potentially toxic pyrrolizidine alkaloids, but absorption is significantly lower through the skin compared with if given orally.