Assertion: chloroquine | /r/ObjectUse | used documented acquired qt prolongation
Facets:
value: with caution in patients with congenital
type: MANNER
Source sentences:
text: Chloroquine should be used with caution in patients with congenital or documented acquired QT prolongation and/or known risk factors for prolongation of the QT interval such as: - cardiac disease e.g. heart failure, myocardial infarction, - proarrhythmic conditions e.g bradycardia (< 50 bpm) - a history of ventricular dysrhythmias - uncorrected hypokalemia and/or hypomagnesemia - and during concomitant administration with QT interval prolonging agents (see section 4.5) as this may lead to an increased risk for ventricular arrhythmias, sometimes with fatal outcome.