Assertion: centromere | /r/HasProperty | nakano et al
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Source sentences:
text: At human artificial chromosomes, altering the chromatin state to more transcriptionally active or inactive configurations by introducing transcriptional activators or silencers results in an imbalance of H3K4me2 and H3K9me3 and leads to loss of the centromere (Nakano et al. 2008).