Assertion: cytochrome c | /r/HasProperty | released into the cytosol
Facets:
value: during apoptosis
type: TEMPORAL
value: from the mitochondria
type: TRANSITIVE-OBJECT
value: by engagement of the fas receptor
type: CAUSE
value: from mitochondria
type: LOCATION
Source sentences:
text: During the process of apoptosis, cytochrome c is released from mitochondria into the cytosol.
text: Once released into cytosol, cytochrome c is known to form a molecular complex with Apaf-1, which then activates caspase cascade leading to expression of many apoptotic events ( 2 – 4 ).
text: So far, it has only been described that cytochrome c is released from the mitochondria to the cytosol.
text: To test the possibility that cytochrome c might be released into the cytosol during apoptosis, we fractionated healthy SL2 cells and apoptotic rpr- or grim-expressing cells, and assayed for cytochrome c in the mitochondrial (heavy membrane) and cytosolic fractions.
text: However, when a cell receives an apoptotic stimulus, cytochrome c is released into the cytosol and triggers programmed cell death through apoptosis.
text: Cytochrome c was released into the cytosol by engagement of the Fas receptor just as in response to chemical-mediated apoptosis.
text: Abstract Several groups have reported that during apoptosis, cytochrome c is released from the mitochondria into the cytosol, but we have found that in apoptotic cells the cytochrome appears to remain with the mitochondria.