Assertion: deuterium's effect | /r/HasProperty | probed
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Source sentences:
text: A primary kinetic isotope effect may be found when a bond to the isotopically-labeled atom is being formed or broken.:427 Depending on the way a kinetic isotope effect is probed (parallel measurement of rates vs. intermolecular competition vs. intramolecular competition), the observation of a primary kinetic isotope effect is indicative of breaking/forming a bond to the isotope at the rate-limiting step, or subsequent product-determining step(s).