Assertion: centromere's dna sequence | /r/HasProperty | necessary
Facets:
value: for kinetochore function in vertebrates
type: PURPOSE
Source sentences:
text: DNA sequences are both necessary and sufficient to specify centromere identity and function in organisms with point centromeres.
text: DNA sequences are both necessary and sufficient to specify centromere identity and function in organisms with point centromeres.
text: In some multicellular organisms, artificial chromosome constructs (4) or chromosome fragments (5) can recapitulate centromere functions, which suggests that specific DNA sequences are necessary.
text: Human centromeric DNA is composed of repetitive α-satellite sequences but centromeres are thought to be epigenetically specified, as centromeric DNA is not well conserved between species and no DNA sequences have been identified that are necessary or sufficient for kinetochore function in vertebrates (see ref. 2 for review).