Assertion: chloroquine | /r/CapableOf | raise the ph
Facets:
value: rapidly
type: MANNER
value: in host-cell lysosomes
type: LOCATION
Source sentences:
text: Chloroquine raises the pH in host-cell lysosomes, which interferes with viruses’ attempts to acidify the lysosomes, a prerequisite to formation of the autophagosomes that cells use to eat themselves.
text: When chloroquine is added after infection, it can rapidly raise the pH and subvert on-going fusion events between virus and endosomes, thus inhibiting the infection.