Assertion: active centromere | /r/HasProperty | regions of centromeric dna
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Source sentences:
text: With the notable exception of CENP-B, these foundation kinetochore proteins are essential: they are found at all active centromeres (regions of centromeric DNA where a functional kinetochore assembles) including neocentromeres, but not at inactive centromeres (regions of centromeric DNA that are not associated with kinetochore assembly), and their depletion results in chromosome missegregation and disruption of mitosis.