Assertion: cytochrome c's effect | /r/HasProperty | important
Facets:
value: the initial phase of apoptosis
type: TEMPORAL
value: with other factors
type: OTHER
value: in regulating
type: OTHER
Source sentences:
text: This synergistic effect of Ca 2+ and peroxidized cardiolipin on MPT induction and cytochrome c release in mitochondria, might be important in regulating the initial phase of apoptosis and also may have important implications in those physiopathological situations, characterized by both Ca 2+ and peroxidized cardiolipin accumulation in mitochondria, such as aging, ischemia/reperfusion and other degenerative diseases.
text: The synergistic effect of Ca2+ and oxidized cardiolipin in the induction of MPT and in the release of cytochrome c from mitochondria, might be important in regulating, together with other factors, the initial phase of apoptosis and also may have implications in those physiological situations, characterized by Ca2+ influx and accumulation of oxidized cardiolipin in mitochondria, such as aging, ischemia and reperfusion and other degenerative diseases.