Assertion: codeine | /r/CapableOf | show no evidence of tumorigenicity
Facets:
value: on a mg/m² basis
type: OTHER
value: at dietary doses
type: TEMPORAL
Source sentences:
text: In 2-year studies in F344/N rats and B6C3F1 mice, codeine showed no evidence of tumorigenicity at dietary doses up to 70 and 400 mg/kg/day, respectively (approximately 9 and 25 times, respectively, the MRHDD dose for adults and children on a mg/m² basis).