Assertion: deuterium | /r/HasProperty | locked in place
Facets:
value: by lowering the temperature
type: MANNER
value: after exchange under native conditions
type: TEMPORAL
Source sentences:
text: After exchange under native conditions, the deuterium at backbone amides is locked in place by lowering the temperature and the pH to a regime where amide exchange is minimized or “quenched” (~ 0 °C and pH 2.5), thus enabling analysis by mass spectrometry.