Assertion: caspase's role | /r/HasProperty | important
Facets:
value: very
type: DEGREE
Source sentences:
text: Hence, the role TNF played in a range of physiological actions was important and the hunt was on to identify TNF and related molecules such as LT.
text: Functionally, the caspases are major regulators of apoptotic cell death pathways, proliferation and inflammation, playing vital roles in the life and death of animal cells.
text: Caspases play an essential role during apoptotic cell death.
text: Given that separase and apoptotic caspases belong to same clade, the CD clan cysteine proteases, coupled with the evidence presented above that separase may possess pro-apoptotic activity, it was of interest to ask whether the predominant pro-apoptotic caspase in C. elegans, CED-3, might function in essential non-apoptotic roles performed by separase.
text: Caspases play a very important role in initiating and executing apoptotic processes in animal cells.
text: The abundance of cleaved and active caspase-3 in axons suggested that this executioner caspase is likely to play an important role in axonal degeneration, and our pharmacological and genetic studies support this contention.