Assertion: diazepam | /r/HasProperty | n-demethylated
Facets:
value: by 2c19
type: TEMPORAL
value: by cyp3a4
type: OTHER
value: to the active metabolite
type: TRANSITIVE-OBJECT
Source sentences:
text: Diazepam is N-demethylated by CYP3A4 and 2C19 to the active metabolite N-desmethylDiazepam, and is hydroxylated by CYP3A4 to the active metabolite temazepam.
text: Hepatic; diazepam is N-demethylated by CYP3A4 and 2C19 to the active metabolite N-desmethyldiazepam, and is hydroxylated by CYP3A4 to the active metabolite temazepam.
text: Diazepam is N-demethylated by CYP3A4 and 2C19 to the active metabolite N-desmethyldiazepam, and is hydroxylated by CYP3A4 to the active metabolite temazepam.
text: Diazepam is N-demethylated by CYP3A4 and 2C19 to the active metabolite N-desmethyldiazepam, and is hydroxylated by CYP3A4 to the active metabolite temazepam.
text: Diazepam is N-demethylated by CYP3A4 and 2C19 to the active metabolite N-desmethyldiazepam, and is hydroxylated by CYP3A4 to the active metabolite temazepam.