Assertion: chloroplast's function | /r/HasProperty | gun6d mutant
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text: Our current understanding of ‘biogenic’ retrograde signals derives almost entirely from the isolation of loss-of-function gun2-gun5 mutants and the gain of function gun6D mutant, all of them involved in tetrapyrrole metabolism, and of the gun1 mutant; only the gun1 mutant exhibits partial uncoupling of nuclear gene expression when chloroplasts are defective by the loss of activity of the genetic machinery (by lincomycin, a chloroplast translation inhibitor) .