Assertion: carbon monoxide | /r/CapableOf | bind to hemoglobin
Facets:
value: reversibly
type: MANNER
value: to form carboxyhemoglobin
type: PURPOSE
value: irreversibly
type: MANNER
value: in place of the oxygen
type: OTHER
value: to create a molecule
type: PURPOSE
value: to form cohb
type: PURPOSE
value: in red blood cells
type: LOCATION
value: in the blood
type: LOCATION
Source sentences:
text: When CO is not ventilated it binds to hemoglobin, which is the principal oxygen-carrying compound in blood; this produces a compound known as carboxyhemoglobin.
text: Carbon monoxide can also bind to haemoglobin but does so about 240 times more tightly than oxygen, forming a compound called carboxyhaemoglobin.
text: When carbon monoxide is breathed into the lungs, it binds with hemoglobin in red blood cells to make carboxyhemoglobin (COHb) which is then transported into the bloodstream.
text: CO has a high affinity for hemoglobin, reversibly binding with hemoglobin and resulting in the formation of carboxyhemoglobin.
text: When inhaled, CO is absorbed through the lungs, where it binds with haemoglobin to form COHb.
text: Carbon monoxide binds to the hemoglobin to create a molecule called carboxyhemoglobin (COHb), which interferes with the body's ability to transport and use oxygen, especially in the brain.
text: When inhaled, it bonds with the hemoglobin in the blood, which is responsible for carrying oxygen throughout the body.
text: When carbon monoxide enters your bloodstream, it bonds with the haemoglobin in place of the oxygen.
text: CO is inhaled in the lungs, perfuses across the alveolar barrier, and binds to hemoglobin to form carboxyhemoglobin.
text: Carboxyhemoglobin (the molecule formed when CO binds to hemoglobin) does not perform oxygen transport, and it rapidly builds up.
text: This means that if both carbon monoxide and oxygen are inhaled, carbon monoxide will preferentially bind to haemoglobin.
text: Second, carbon monoxide irreversibly binds with hemoglobin to form carboxyhemoglobin, thus reducing the number of red blood cells available to transport oxygen to other cells of the body.