Assertion: centromere's region | /r/LocatedNear | the centromere
Facets:
value: in vertebrates
type: OTHER
Source sentences:
text: For example, H3 and H4 in heterochromatic regions surrounding the centromere can be methylated at Lys9 (H3K9me2 and H3K9me3)2,63 and Lys20 (H4K20me3)65,66, and these modifications serve to recruit proteins such as cohesin67 and to maintain the structure of pericentric chromatin.
text: In vertebrates, heterochromatic regions surround centromeres in which the chromatin assembly factor CAF-1 deposits H3 and promotes H3K9 mono-methylation.
text: In S. pombe and higher eukaryotes the region surrounding the centromere is heterochromatic, and in these systems it seems that the factors that are important for establishing heterochromatin are involved in establishing the cohesin protective domain.
text: Cohesin rings, especially in budding yeast, are also located in the region surrounding the centromere.