Assertion: cytochrome c | /r/CapableOf | activate major apical caspase
Facets:
value: in the cytoplasm
type: LOCATION
Source sentences:
text: Once in the cytoplasm, cytochrome c activates a major apical caspase, caspase-9, in concert with Apaf-1 and dATP (or ATP), and the activated caspase-9 subsequently activates an effector caspase, caspase-3 (4, 5).