Assertion: chloroform | /r/AtLocation | use
Facets:
value: by the time
type: TEMPORAL
Source sentences:
text: By the time the American Civil War broke out in 1861, both ether and chloroform had been in use for several years as methods of surgical anesthesia.
text: By the time the American Civil War broke out in 1861, both ether and chloroform had been in use for several years as methods of surgical anesthesia.