Assertion: centromere's sequence | /r/HasProperty | conserved
Facets:
value: between organisms
type: OTHER
value: widely
type: DEGREE
Source sentences:
text: Whereas CENP-A normally associates with the HOR of human centromeres (1, 2, 11) where it marks kinetochore assembly, the fact that neocentromeres, which contain CENP-A but lack α-satellite sequence, are stably maintained during cell divisions (9, 12⇓⇓–15), poses the question of why repetitive sequences are widely conserved between organisms.
text: Likewise, all foreign sequences that maintained episomes contained a 500-bp region with GC content beneath this threshold.
text: Abstract Point centromeres are specified by a short consensus sequence that seeds kinetochore formation, whereas regional centromeres lack a conserved sequence and instead are epigenetically inherited.
text: In contrast, in most eukaryotes, regional centromeres span thousands to millions of base pairs and lack a conserved sequence that seeds kinetochore formation (1, 2).