Assertion: cur | /r/CapableOf | induce apoptosis
Facets:
value: in acute myeloid leukemia cells
type: OTHER
value: in turn
type: TEMPORAL
Source sentences:
text: For example, CUR induced apoptosis via the upregulation of the proapoptotic Bax and the downregulation of the antiapoptotic proteins such as myeloid cell leukemia 1 (Mcl1) and Bcl2 in human melanoma cells.
text: In melanoma cells, CUR inhibited NF-κB in a dose-dependent manner and, in turn, induced apoptosis .
text: In vitro studies have also proved that CUR may induce apoptosis in acute myeloid leukemia cells via a simultaneous attenuation of the two critical prosurvival signaling pathways such as the Akt/mammalian target of rapamycin (