Assertion: cartilage's matrix | /r/HasProperty | ecm
Facets:
Source sentences:
text: The three key elements for both morphogenesis and regeneration are inductive signals for morphogenesis, stem cells that respond to morphogenetic and growth signals, and the scaffolds of extracellular matrix (ECM).
text: The articular cartilage function is dependent on the molecular composition of the extracellular matrix (ECM).
text: As long as they are free to move, chondroblasts produce the elements of the extracellular matrix (ECM).
text: Chondrocytes are first chondroblast cells that produce the collagen extracellular matrix (ECM) and then get caught in the matrix.
text: Mesenchyme tissue differentiates into chondroblasts and begins secreting the molecules that form the extracellular matrix (ECM).
text: Emerging evidence suggests that identification of appropriate model systems that recapitulate the physical and biochemical signals present in complex cellular microenvironments ( 11 ), such as those from surrounding cell populations ( 12 ), the extracellular matrix (ECM)
text: Hyaline cartilage is comprised of 95% extracellular matrix (ECM) (dry weight) and only 5% of sparsely distributed chondrocytes .
text: These chondrogenic cells differentiate into so-called chondroblasts, which then synthesize the cartilage extracellular matrix (ECM), consisting of a ground substance (proteoglycans, glycosaminoglycans for low osmotic potential) and fibers.
text: In biology, the extracellular matrix (ECM) is a three-dimensional network of extracellular macromolecules, such as collagen, enzymes, and glycoproteins, that provide structural and biochemical support to surrounding cells.
text: Although a variety of xeno extracellular matrix (ECM) have effectively been used in both animal and human trials in restoration or substitution of numerous imperfections, the widespread use of caprine conchal cartilage matrix is not ascertained as an allogenic or autogenic substitute in transplantations.
text: In hyaline cartilage, pluripotent cells at different stages of differentiation exhibit expression of different genes, including fibronectin, hyaluronan, tenascin, type I collagen, type II collagen, minor type IX and XI collagens, proteoglycans, matrilins, and cartilage oligomeric protein (COMP) , which participate in the formation of abundant extracellular matrix (ECM).
text: In 3D culture, chondrocytes display a similar morphology as in cartilage and produce a cartilage-like extracellular matrix (ECM), rich in type II collagen2,3 whereas in monolayer culture they quickly dedifferentiate into fibroblast and a switch from type II to type I collagen expression
text: When exposed to growth factors the MSCs secrete an extracellular matrix (ECM), which works as a lubricant and shock absorber for the bones that meet and move against each other at the joints.
text: The extracellular matrix (ECM) chiefly comprises water (70% to 80%) and includes type II collagen and, to a lesser extent, glycoproteins (PGs; Table 1).
text: (PLA) coating  porous tantalum , decellularized osteochondral extracellular matrix (ECM) , or poly(ester-urethane) scaffolds .
text: Those factors include a more dense extracellular matrix (ECM), a higher mineral content than bone ECM, and extremely low cellular oxygen levels, which they think may reduce or prevent degradation.
text: Other disadvantages included loss of the chondrocytic phenotype in cells expanded in monolayer culture, lack of applicability of the technique to large lesions, the limited proliferative capacity of chondrocytes, poor functionality and quality of the extracellular matrix (ECM) synthesized, and limited technical efficacy in patients older than 40 years (because of poor cellular activation).
text: In addition to those preceding biopolymers, biologic scaffold materials consisting of extracellular matrix (ECM), such as decellularized urinary bladder matrix (UBM), have aroused great attention in the field of cartilage regeneration.
text: Tendinopathies can be caused by a number of factors relating to the tendon extracellular matrix (ECM), and their classification has been difficult because their symptoms and histopathology often are similar.
text: Conversely, bovine chondrocytes cocultured adjacent to human fibroblasts were not stimulated to produce cartilage extracellular matrix (ECM) and, in fact, demonstrated a significant decrease in GAG and collagen production compared to chondrocytes cultured alone.
text: Chondrocytes demonstrate distinctive features such as being metabolically active to maintain the turnover of extracellular matrix (ECM) by synthesising glycoprotein, collagens, proteoglycans, and hyaluronan.