Assertion: caspase | /r/HasProperty | processed to two-chain active enzyme
Facets:
value: by cleavage at internal asp residues
type: MANNER
value: themselves
type: MANNER
value: from the single-chain zymogen
type: OTHER
Source sentences:
text: Since all caspases cleave their substrates after Asp residues and are themselves processed from the single-chain zymogen to the two-chain active enzyme by cleavage at internal Asp residues, it follows that an upstream caspase can process a downstream zymogen.
text: Since all caspases cleave their substrates after Asp residues and are themselves processed from the single-chain zymogen to the two-chain active enzyme by cleavage at internal Asp residues, it follows that an upstream caspase can process a downstream zymogen (6-8).