Assertion: effector caspase | /r/HasProperty | supplemental material
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text: We demonstrated that Q-VD-OPH was more effective than Z-VAD-FMK in blocking caspase-3– and caspase-7–mediated poly(ADP-ribose) polymerase (PARP) cleavage, which is a prototypical substrate of effector caspases (Supplemental Figure 1A; supplemental material available online with this article; https://doi.org/10.1172/JCI95127DS1).
text: We demonstrated that Q-VD-OPH was more effective than Z-VAD-FMK in blocking caspase-3– and caspase-7–mediated poly(ADP-ribose) polymerase (PARP) cleavage, which is a prototypical substrate of effector caspases (Supplemental Figure 1A; supplemental material available online with this article; https://doi.org/10.1172/JCI95127DS1).