Assertion: cytochrome c | /r/CapableOf | interact with apoptotic protease
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text: permanent focal ischemia.10 Overexpression of human glutathione (GSH) peroxidase protects brain against transient focal ischemia.11 Fujimura et al12,13 presented a hypothesis that SOD1 and SOD2 can reduce apoptosis resulting from focal cerebral ischemia by blocking cytosolic release of cytochrome c, which interacts with apoptotic protease activating factor-1 (Apaf-1) and caspase-9, thereby playing a crucial role in apoptosis mediated by mitochondria.14,15