Assertion: clover's effect | /r/AtLocation | clinical trials
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text: Few adverse effects of red clover have been reported in clinical trials at doses of up to 160 mg isoflavones per day.1, 34, 41 Loss of appetite, pedal edema, and abdominal tenderness have been reported after high doses of isoflavones (4 or 8 mg/kg).42 Free and total genistein and daidzein disappeared rapidly from the plasma in this study and are unlikely to accumulate in the body with regular use of 2 to 3 times daily.