Assertion: centromere | /r/HasProperty | essential
Facets:
value: for proper chromosome segregation
type: PURPOSE
value: for cell division
type: PURPOSE
value: on every eukaryotic
type: LOCATION
value: for genetic stability
type: PURPOSE
value: to the division of cells
type: PURPOSE
Source sentences:
text: They are essential to the division of cells and ensure the accurate segregation of chromosomes.
text: The kinetochore is therefore essential for the chromosome segregation that is classically associated with mitosis and meiosis.
text: The centromere is an essential site on every eukaryotic chromosome, and errors in this can lead to a wide range of diseases, including cancer and aneuploidy-related disorders such as Down's syndrome, and to death.
text: The centromere is an essen tial site on every eukaryotic
text: Central to the proper segregation of chromosomes at cell division is the centromere, an essential region that in eukaryotes must be present on every chromosome.
text: Centromeres, and the kinetochores that assemble on them, are essential for accurate chromosome segregation.
text: The centromere is essential for chromosome segregation because it is the site at which the kinetochore assembles to control microtubule attachment and chromosome movement.
text: Centromeres are the control centers for chromosomes, and thus are essential for accurate segregation in cell division.
text: The centromere is a chromosomal structure that is essential for the accurate segregation of replicated eukaryotic chromosomes to daughter cells.
text: Centromeres are therefore essential for genetic stability and there are several examples where defects in centromere function are associated with aneuploidy (aberrant chromosome number) causing birth defects or with cancer.
text: The centromere is essential for the segregation of
text: Although centromeres are essential for cell division, their sequences are not conserved and evolve rapidly.
text: The centromere consists of DNA material as well as multi-protein complexes such as the kinetochore and are essential for binding of the chromatids to each other.
text: Centromeres, and the kinetochores that assemble on them, are essential for accurate chromosome segregation.
text: The kinetochore is a proteinaceous complex that is essential for proper chromosome segregation.
text: The kinetochore is a proteinaceous complex that is essential for proper chromosome segregation.