Assertion: centrosome | /r/HasProperty | fig
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text: Spd2 normally helps to recruit Cnn into the PCM, and Cnn in turn helps to maintain Spd2 within the PCM, thus potentially forming a positive-feedback loop that helps to drive the dramatic expansion of the scaffold during centrosome maturation166 (Fig.
text: Given the annotation of AKNA as an AT-hook transcription factor6, we were surprised to find specific immunofluorescence signals at centrosomes (Fig.
text: In a small fraction of the cells (less than 30%) the ESCRT III components CHMP2A and CHMP2B were detected in the vicinity of the centrosome (Fig.
text: CHMP2B, which we occasionally observed associated with the centrosome (Fig.
text: However, co-expression of almost every ESCRT III subunit together with GFP-VPS4EQ led to trapping of VPS4EQ in these internal structures and to loss of GFP-VPS4EQ from the centrosome (Fig.
text: In contrast to expression of GFP-VPS4 and GFP-VPS4EQ, GFP-VPS4EQΔMIT rarely localized to the centrosome (GFP-VPS4, 68%; GFP-VPS4EQ, 87%, GFP-VPS4EQΔMIT, 11%) (Fig.