Assertion: chlorobenzene | /r/HasAspect | no effect
Facets:
value: on isocitrate dehydrogenase
type: LOCATION
value: on cyto-
type: LOCATION
value: on benzofa
type: LOCATION
value: on pyrene hydroxylase
type: LOCATION
value: on detoxification of epn
type: TRANSITIVE-OBJECT
Source sentences:
text: In adult male albino rats, chlorobenzene at oral doses of 200, 400, or 800 mg/kg/day for 14 days significantly decreased cytochrome P450 and glucose-6-phosphatase at the high dose and increased glucuronyl trans- ferase at all doses but had no effect on isocitrate dehydrogenase, cyto- chrome-c reductase, benzofa~pyrene hydroxylase, or detoxification of EPN (ethyl p-nitrophenyl phenylphosphonothionate) (Carlson and Tardiff,