Assertion: cytochrome c | /r/CapableOf | activate caspase
Facets:
value: through its effects on a protein
type: MANNER
value: in the cytosol
type: LOCATION
Source sentences:
text: Cytochrome c activates caspases through its effects on a protein called apoptosis protease-activating factor-1 (Apaf-1).
text: Cytochrome c activates caspases through its effects on a protein called apoptosis protease-activating factor-1 (Apaf-1).
text: It is clear that in a cell-free system under appropriate conditions, cytochrome c is able to activate caspases, implying that it can perform this function in intact cells undergoing apoptosis.
text: In the cytosol, cytochrome c activates the caspases — a family of killer proteases — through formation of a complex with Apaf-1 (for apoptotic-protease-activating factor-1), procaspase-9 and ATP or dATP.