Assertion: cancer inhibiting apoptosis | /r/HasProperty | induction of cyp2e1
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Source sentences:
text: Among the several mechanisms proposed to explain alcohol induced hepatocyte apoptosis, induction of CYP2E1, one of the many cytochrome P450 isoforms, and CYP2E1 dependent formation of reactive oxygen species (ROS) and lipid peroxides, appears to be one of the possible explanations.84,85 ROS, whose production is driven by increased availability of the reduced form of nicotinamide adenine dinucleotide due to mitochondrial acetaldehyde metabolism, may cause mitochondrial dysfunction and release of proapoptotic factors such as cytochrome c into the cytosol where they promote caspase activation.