Assertion: adenosine | /r/CapableOf | activate a 2a r
Facets:
value: through interactions with h3 and h7
type: MANNER
Source sentences:
text: Therefore, although it might still be involved, the allosteric interaction, which leads to a lower affinity of D 2 R for dopamine when adenosine is activating A 2A R, does not seem to be the main mechanism underlying the A 2A R–D 2 R functional interaction in the A 2A R–D 2 R heteromer.
text: Adenosine and NECA activate the A 2A R through interactions with H3 and H7 that are absent in the interactions between the receptor and the inverse agonist ZM241385 (Fig. 2).