Assertion: amiodarone | /r/HasProperty | metabolized in the liver
Facets:
value: mainly
type: DEGREE
value: by cytochrome p450 3a4
type: OTHER
value: extensively
type: DEGREE
Source sentences:
text: Amiodarone is extensively metabolized in the liver by cytochrome P450 3A4 and can affect the metabolism of numerous other drugs.
text: Since amiodarone is mainly metabolized in the liver, any damage to the liver from any cause would hamper amiodarone metabolism and lead to a vicious cycle of accumulation of amiodarone and further amiodarone-induced hepatic damage .