Assertion: arsenic's role | /r/HasProperty | demonstrated in experiment
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text: The role of AS3MT as a primary As(III) methyltransferase in mammals has been demonstrated in experiments with genetically modified mice.112 Variations (polymorphism) of human AS3MT are likely to be responsible for the interindividual differences in As methylation patterns, since such methylation is linked to an increased risk of As-induced cancers.94,113 Scheme 4.