Assertion: barbiturate's use | /r/HasSubevent | tolerance
Facets:
value: to the drug
type: OTHER
Source sentences:
text: Regular use over time may result in a tolerance to the drug, leading the user to increase the quantity consumed.
text: Barbiturates have a high potential for abuse, and prolonged use can result in tolerance and physical dependence.
text: Prolonged, continuous use of butorphanol tartrate may result in physical dependence or tolerance (a decrease in response to a given dose).
text: Prolonged use of ethchlorvynol may result in tolerance and physical and psychological dependence.
text: Regular use may result in tolerance.
text: Chronic use of opioids can result in tolerance, which means that users must take higher doses to achieve the same effects.
text: Compulsive and repetitive use may result in tolerance to the effect of the drug and withdrawal symptoms when use is reduced or stopped.