Assertion: antibody's affinity | /r/CapableOf | abrogate anti-tumor activity
Facets:
value: respectively
type: MANNER
Source sentences:
text: It has been documented that the anti-CD40 human IgG1 antibody produces potent antitumor activity in tumor models with the mFcγR−/−hFCGR2B genotype, depleting (by N297A mutation) or increasing (by S267E mutation) the binding affinity to hFcγRIIB, respectively abrogating or enhancing anti-tumor activity .