Assertion: adenosine | /r/CapableOf | stimulate somatostatin secretion
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text: Meanwhile, in experiments performed in isolated perfused stomachs of mice bearing genetic ablation of A2A receptor, adenosine was demonstrated to exhibit differential dose-dependent effects on acid secretion, so that at high concentrations (>1 μM), adenosine acted through A2A stimulating somatostatin secretion but when adenosine concentrations were below 10 nM it acted mainly through its inhibitory A1 receptor (Yang et al., 2009) decreasing somatostatin production.