Assertion: adp | /r/CapableOf | amplify platelet responses
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text: Although itself a weak agonist, ADP plays a key role in platelet function because, when it is secreted from the platelet-dense granules where it is stored, it amplifies the platelet responses induced by other platelet agonists8,10 and stabilizes platelet aggregates.11–13 Transduction of the ADP-induced signal involves inhibition of adenylyl cyclase and a concomitant transient increase in the concentration of cytoplasmic Ca2+, resulting from both Ca2+ influx and mobilization of internal stores (see Chapter 16).