Assertion: bilirubin | /r/CapableOf | exhibit marginal neurotoxicity
Facets:
value: on own
type: MANNER
Source sentences:
text: By applying patch-clamp electrophysiology, Ca 2+ imaging, and cell death assays to the medial vestibular nucleus (MVN) neurons of neonatal mice, we demonstrated that bilirubin exhibited marginal neurotoxicity on its own, but potentiated the currents mediated by ASIC1a channels in an acidic environment via Ca 2+ -dependent intracellular signaling, and jointly boosted neuronal excitability, Ca 2+ overload, and cell death.