Assertion: apoptosis | /r/HasProperty | induced in response
Facets:
value: with the increase in autophagy
type: OTHER
value: to er stress
type: CAUSE
Source sentences:
text: Apoptosis can be induced in response to many external stimuli (extrinsic pathway) including activation of cell surface receptors such as Fas, TNFR1 (tumor necrosis factor receptor 1), TRAIL-R1 (TNF-related apoptosis-inducing ligand receptor 1), TRAIL-R2, p75-NGFR (p75-nerve growth factor receptor) and others (Wajant et al. 2003).
text: As another example of this complex interplay among cell death pathways, studies have shown that apoptosis and autophagy are activated in response to metabolic stress and that both autophagy and apoptosis are induced in response to ER stress, with the increase in autophagy being a contributing factor to ER-induced apoptosis .