Assertion: physical dependence | /r/CapableOf | produce increase
Facets:
value: in nr2a
type: LOCATION
value: in nmda receptor subunits nr1
type: LOCATION
Source sentences:
text: Physical dependence on opioids has been observed to produce an elevation of extracellular glutamate, an increase in NMDA receptor subunits NR1 and NR2A, phosphorylated CaMKII, and c-fos.