Assertion: amiodarone's heart rate | /r/CapableOf | increase the demand
Facets:
value: together
type: MANNER
value: for oxygen
type: PURPOSE
value: by the heart
type: MANNER
Source sentences:
text: In unstable angina (excluding variant angina), amlodipine can cause a reflex increase in cardiac contractility (how hard the ventricles squeeze) and heart rate, which together increase the demand for oxygen by the heart itself.