Assertion: alkaloid's nitrogen | /r/HasProperty | introduced
Facets:
value: in order to increase solubility
type: PURPOSE
value: in order to increase absorption
type: PURPOSE
Source sentences:
text: In order to increase solubility and absorption, the basic nitrogen was introduced, leading to the analog azaindole and related compounds exhibiting the same NK1 binding affinity with the series of 2-aryl indole NK1 receptor antagonists (Cooper et al., 2001).