Assertion: adenosine's receptor | /r/HasProperty | gpcrs
Facets:
Source sentences:
text: Adenosine affects several functions in the body, exerting its physiological effects through regulation of four G-protein coupled receptors (GPCRs) named A 1 , A 2A , A 2B , and A 3 , characterized by different affinities for adenosine, tissue distribution, and coupling with effector systems.
text: Adenosine binds to four specific cell membrane G-protein-coupled receptors (GPCRs) known as adenosine receptors (ARs): A 1 , A 2A , A 2B , and A 3 .
text: However, in the extracellular space adenosine is a signaling molecule, able to bind to and activate four different G protein-coupled receptors (GPCRs) designated A1, A2A, A2B, and A3 (Fredholm et al., 2001a).
text: A limited number of strategies can be applied to measure inverse agonism of ligands acting at G protein-coupled receptors (GPCRs).
text: Adenosine receptors (ARs) comprise the P1 class of purinergic receptors and belong to the largest family of integral membrane proteins in the human genome, the G protein-coupled receptors (GPCRs).
text: I am a medicinal chemist with interests in the structure and pharmacology of receptors and in developing drugs that act as agonists or antagonists of G protein-coupled receptors (GPCRs).