Assertion: acetaminophen's use | /r/CapableOf | decrease opioid efficacy
Facets:
value: possibly
type: DEGREE
Source sentences:
text: Concomitant use of hydrocodone bitartrate and acetaminophen tablets with CYP3A4 inducers or discontinuation of an CYP3A4 inhibitor could decrease hydrocodone plasma concentrations, decrease opioid efficacy or, possibly, lead to a withdrawal syndrome in a patient who had developed physical dependence to hydrocodone.