Assertion: antibody's fragment | /r/HasProperty | fab
Facets:
Source sentences:
text: We obtained a structure of CD20 in complex with RTX, revealing CD20 as a compact double-barrel dimer bound by two RTX antigen-binding fragments (Fabs), each of which engages a composite epitope and an extensive homotypic
text: One hint comes from epitope fine-mapping studies showing that residue Asn176 of ECL2 is involved in OBZ binding, but not RTX binding, and that OBZ binds to ECL2 peptides (but not CD20+ cells) with higher affinity than RTX (5); another hint comes from x-ray crystallographic structures of peptide-bound antigen-binding fragments (Fabs) of RTX, OCR, and OBZ, in which RTX and OCR approach the ECL2 epitope at a similar angle, tilted approximately 70° away from the angle at which OBZ approaches the same peptide (4–6).
text: There are several different types of antibody heavy chains that define the five different types of crystallisable fragments (Fc) that may be attached to the antigen-binding fragments (Fab).
text: In the more than 60,000 articles manually curated by Labome only a few articles cited applications of antibody Fab fragments.
text: CD20 forms a dimer and each monomer binds one rituximab antigen-binding fragment (Fab) to give 2:2 stoichiometry.
text: Two human monoclonal antibody Fab fragments (HMab) (cloned before the emergence of S-OIV) were found to neutralise H1N1 strains.