Assertion: calcitonin's role | /r/HasProperty | synthesized in the ~ 1% of enteric neurons
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text: Indeed, there is no doubt that exogenous bath applied 5-HT causes membrane depolarization of myenteric neurons,121 and there is no doubt that there are numerous receptors for 5-HT expressed all throughout the GI tract and that some enteric neurons also synthesize 5-HT.20 However, despite these circumstantial findings, there is still major uncertainty about the functional role of neuronal 5-HT (i.e., synthesized in the ~ 1% of enteric neurons that are indeed 5-HT immunoreactive).