Assertion: barbiturate | /r/CapableOf | act as depressant
Facets:
value: by reducing the excitability of glutamate
type: MANNER
value: on the central nervous system
type: LOCATION
Source sentences:
text: Barbiturates are substances that act as depressants on the central nervous system.
text: In this case, the barbiturates selectively antagonize the AMPA and kainate receptors, which is why they also act as depressants by reducing the excitability of glutamate.