Assertion: caffeine | /r/HasProperty | metabolized in the liver
Facets:
value: into three dimethylxanthines
type: OTHER
value: by the cyp1a2 isozyme
type: OTHER
value: via a single demethylation
type: MANNER
value: primarily
type: DEGREE
value: into three primary metabolites
type: OTHER
Source sentences:
text: Caffeine is metabolized in the liver via a single demethylation , resulting in three primary metabolites, paraxanthine (84%), theobromine (12%), and theophylline (4%), depending on which methyl group is removed.
text: Caffeine is metabolized in the liver by the cytochrome P450 oxidase enzyme system, in particular, by the CYP1A2 isozyme, into three dimethylxanthines, each of which has its own effects on the body:
text: Caffeine is metabolized in the liver into three primary metabolites: paraxanthine (84%), theobromine (12%), and theophylline (4%)
text: Caffeine is metabolized in the liver by the cytochrome P450 oxidase enzyme system (specifically, the 1A2 isozyme) into three metabolic dimethylxanthines, which each have their own effects on the body:
text: Caffeine is metabolized in the liver via a single demethylation , resulting in three primary metabolites, paraxanthine (84%), theobromine (12%), and theophylline (4%), depending on which methyl group is removed.
text: Caffeine is metabolized in the liver by the cytochrome P450 oxidase enzyme system, in particular, by the CYP1A2 isozyme, into three dimethylxanthines, each of which has its own effects on the body:
text: Caffeine is primarily metabolized in the liver by the cytochrome P450 oxidase enzyme system; in particular, by the CYP1A2 enzyme.