Assertion: antibody's fragment | /r/HasProperty | scfv
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Source sentences:
text: Single chain variable fragments (scFv) are connected to the variable domain of the heavy and light chain via a short linker peptide.
text: Genetic engineering methods allow the production of single chain variable fragments (scFv), which are F V type fragments that consist of the V H and V L domains linked by an engineered flexible linker peptide (Figure 1) .
text: For instances, expression of a single-chain variable fragment (scFv) derived from the 3B12A monoclonal antibody against the TDP-43 nuclear export signal in HEK293A cells or after in utero electroporation of its expression vector promoted the proteolysis of TDP-43 aggregates in cultured cells and embryonic mouse brain .
text: Therefore, it is possible to use antibody fragments incorporating the specificity-providing regions within a single-chain variable fragment (scFv), which can be further engineered for cytosolic stability, to target intracellular antigens (15, 16).