Assertion: antibody's fragment | /r/HasAspect | limitation
Facets:
value: due to their bulky
type: CAUSE
Source sentences:
text: The possibility of using antibodies to stabilize the conformation of proteins that undergo crystallization trials has been recognized since long time [157–159]. Nevertheless, conventional antibodies and their fragments have limitations due to their bulky mass (IgG and Fab fragment) or low stability (scFv) and, therefore, other molecules have been proposed, such as affibodies, fibronectin, and DARPins