Assertion: antibody | /r/CapableOf | bind the antigen
Facets:
value: generally
type: MANNER
value: on hepatitis c virus
type: LOCATION
value: more tightly
type: MANNER
value: more tightly.[/hidden
type: MANNER
value: specifically
type: MANNER
Source sentences:
text: In Noelle v. Lederman, 26 the Federal Circuit held that the written description requirement was violated where the claims at issue covered antibodies that bound the antigen CD40CR generally, because the patent specification described only the mouse form of CD40CR and did not describe human or other CD40CR antigens.
text: Back in the 1990s, a company could pursue broad patent protection by merely claiming “an antibody that binds to antigen (fill in the region),” without disclosing an actual antibody that has been shown to bind that antigen.
text: DNA coding for the part of the antibody that specifically binds antigen can be combined with DNA coding for a protein that is known to tightly bind the radioactively labelled metal.
text: The antibodies bind to pathogens, and can do so in different formations such as: opsonization (2a), neutralisation (2b), and agglutination (2c).
text: However, if the two antigens are too close (≤3 nm), or too far apart (≥29nm), the antibody can only bind to one antigen (monovalent binding) .
text: Take, for example, patents which disclose the antibody by either the paratrope (the part of the antibody that binds to the antigen or the target protein) or the epitope (the part of the target protein that the antigen binds to.)
text: the Federal Circuit held that the written description requirement was violated where the claims at issue covered antibodies that bound the antigen CD40CR generally, because the patent specification described only the mouse form of CD40CR and did not describe human or other CD40CR antigens.
text: After blocking the unbound sites on the plate, patient serum is added; if antibodies are present (primary antibody), they will bind the antigen.
text: __ takes place, which means the antibodies produced after the second injection will on average bind the antigen more tightly.
text: we inject an animal with the same antigen a second time a few weeks after the first, affinity maturation takes place, which means the antibodies produced after the second injection will on average bind the antigen more tightly.[/hidden-answer]
text: For example, a blood sample from a patient suspected of having hepatitis C can be screened for the virus using antibodies that bind to antigens on hepatitis C virus.
text: A sufficient incubation period is provided to allow the antibodies to bind to the antigens.
text: If the patient is indeed infected with hepatitis C virus, the antibodies will bind to the antigens, yielding a positive test result.
text: Antibodies bind antigen with the help of a VHH fragment that can identify specific and unique conformational epitopes by the presence of its long complementary determining regions (CDR3).
text: To combat pathogens that replicate outside cells, antibodies bind to pathogens to link them together, causing them to agglutinate.