Assertion: ace inhibitor's effect | /r/CapableOf | predispose susceptible individuals
Facets:
value: to clinically important hyperkalemia
type: TRANSITIVE-OBJECT
Source sentences:
text: The mechanism by which the use of trimethoprim can precipitate hyperkalemia in users of ACEIs or ARBs is related to an amiloridelike inhibition of sodium channels in the luminal membrane of the distal tube.11,12 Consequently, sodium reabsorption and potassium secretion are impaired, resulting in an antikaliuretic effect that may predispose susceptible individuals to clinically important hyperkalemia.