Assertion: thoracic aortic aneurysm | /r/RelatedTo | genetic cause
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text: Thoracic aortic aneurysms are more likely to be associated with a genetic cause and are further subdivided into subgroups involving the ascending aorta (60%), aortic arch (10%), descending aorta (40%) and thoracoabdominal aorta (10%).5 TAAs, which can occur at a young age without significant cardiovascular risk factors are commonly stratified into either clusters of "syndromic" disorders with extravascular organ involvement or seemingly isolated aberrations denoted "non-syndromic" disorders.6 Table 1 briefly outlines these disorders based upon the mechanistic pathway, involved genetic lesion, and characteristic phenotype.