Assertion: atenolol | /r/HasSubevent | fourth-line agent
Facets:
value: in the management of hypertension
type: TRANSITIVE-OBJECT
Source sentences:
text: Atenolol was the main β-blocker identified as carrying a higher risk of provoking type 2 diabetes, leading to its downgrading in the United Kingdom in June 2006 to fourth-line agent in the management of hypertension.