Assertion: resulting agglutination | /r/HasProperty | measured as a function of analyte
Facets:
value: in the blood sample
type: OTHER
Source sentences:
text: Accordingly, the present invention applies to the determination of an analyte in a blood sample by latex agglutination immunoassay wherein (a) an aqueous reaction mixture is formed by combining the blood sample with a multivalent latex antibody reagent comprising an anti-analyte antibody, or a fragment thereof, bound to a water suspensible latex particle, and additionally when the analyte is only monovalent, with an agglutinator reagent comprising a plurality of epitopic binding sites for the anti-analyte antibody or fragment thereof, and (b) the resulting agglutination in the aqueous reaction mixture is measured as a function of analyte in the blood sample.
text: Accordingly, the present invention applies to the determination of an analyte in a blood sample by latex agglutination immunoassay wherein (a) an aqueous reaction mixture is formed by combining the blood sample with a multivalent latex antibody reagent comprising an anti-analyte antibody, or a fragment thereof, bound to a water suspensible latex particle, and additionally when the analyte is only monovalent, with an agglutinator reagent comprising a plurality of epitopic binding sites for the anti-analyte antibody or fragment thereof, and (b) the resulting agglutination in the aqueous reaction mixture is measured as a function of analyte in the blood sample.
text: the resulting agglutination in the aqueous reaction mixture is measured as a function of analyte in the blood sample, °2 5 the improvement which comprises forming the aqueous reaction mixture to have a pH of about 8.5 or greater, whereby nonspecific agglutination of the latex reagent due to the presence of hemoglobin in the blood sample is substantially overcome.
text: Accordingly, the present invention applies to the determination of an analyte in a blood sample by latex agglutination immunoassay wherein an aqueous reaction mixture is formed by combining the blood sample with a multivalent latex antibody reagent comprising an anti-analyte antibody, or a fragment thereof, bound to a water suspensible latex particle, and additionally when the analyte is only monovalent, with an agglutinator reagent comprising a plurality of epitopic binding sites for the anti-analyte antibody or fragment thereof, and the resulting agglutination in the aqueous reaction mixture is measured as a function of analyte in the blood sample.