Assertion: acetylcholine's mechanism | /r/CapableOf | alter neuron signaling
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text: A proposed mechanism that may explain cognitive dysfunction in patients with immune disorders is suppression of the cholinergic anti-inflammatory pathway leading to heightened secretion of TNF-α, altering astrocyte-neuron signaling, leading to a cascade resulting in a restructuring of the excitability of hippocampal synapses (111).