Assertion: naïve antibody | /r/CapableOf | show discrete conformational change
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text: Another study based on an elastic network model also suggested that, in the absence of antigen, the fluctuations of the naïve and mature 48G7 were similar, but their binding mechanisms could differ depending on response to antigen binding; the naïve antibody shows a discrete conformational change induced by antigen, whereas the mature antibody shows lock-and-key binding (62).