Assertion: acetaldehyde | /r/HasProperty | mutagenic
Facets:
value: in mammalian cells
type: LOCATION
value: in in vitro studies
type: OTHER
value: unfortunately
type: MANNER
Source sentences:
text: Unfortunately, acetaldehyde is mutagenic and carcinogenic being responsible of DNA damage and of several cancer-promoting effects (Dellarco, 1988; Seitz and Stickel, 2010).
text: In in vitro studies, acetaldehyde was mutagenic in mammalian cells (Wangenheim and Bolcsfoldi, 1986, 1988; He and Lambert, 1990), induced aneuploidy in Saccharomyces cerevisiae (Albertini et al., 1993; Ristow et al., 1995), Chinese hamster embryo cells and rat skin fibroblasts, and increased the frequency of micronuclei in rat skin fibroblasts and human lymphocytes (Bird et al., 1982; Dulout and Furnus, 1988; Migliore and Nieri, 1991).