Assertion: boric acid's effect | /r/HasProperty | developmental toxicity
Facets:
Source sentences:
text: The Panel referenced the USEPA IRIS document and stated that basing the TK intraspecies variability uncertainty factor on the pregnant human is appropriate because this ' is the population associated with B's [boron] critical effect [developmental toxicity] and thus, its choice fulfills several criteria for endpoint selection from the existing guidelines."Furthermore, B's elimination is the kinetic area with the most variability-- absorption and distribution of B are expected to be very similar among humans and B is not metabolized.'
text: The Panel referenced the USEPA IRIS document and stated that basing the TK intra-species variability uncertainty factor on the pregnant human is appropriate because this is the population associated with B's [boron] critical effect [developmental toxicity] and thus, its choice fulfills several criteria for endpoint selection from the existing guidelines.
text: The critical effects in several species [of borates] are male reproductive toxicity and developmental toxicity.