Assertion: bismuth's use | /r/CapableOf | see precaution
Facets:
value: to pregnant rats
type: TRANSITIVE-OBJECT
value: at various doses
type: MANNER
Source sentences:
text: PYLERA is contraindicated in women who are pregnant because treatment of Helicobacter pylori infection can be delayed in pregnant women, and the use of drugs of the tetracycline class during the second and third trimester pregnancy can also cause permanent discoloration of the teeth (yellow-gray brown) and possibly inhibit bone development [see WARNINGS AND PRECAUTIONS and Data]. Administration of oral tetracycline to pregnant rats at various doses resulted in yellow fluorescence in teeth and bones in the newborn animals.