Assertion: adenosine's action | /r/HasProperty | formed at increased metabolic rate
Facets:
value: under physiological and pathophysiological conditions
type: OTHER
Source sentences:
text: 1) adenosine injected or infused into the renal artery is reaching all structures of the kidney not taking into account the heterogeneity of its local generation under physiological conditions, 2) high intra-arterial concentrations of exogenously administered adenosine may activate a variety of endothelial responses like release of prostaglandins or nitric oxide (NO) which may not be induced by increases of endogenous adenosine released into the interstitium, and 3) the actions of endogenous adenosine being released or formed at an enhanced rate under physiological and pathophysiological conditions, such as an increased metabolic rate or hypoxia, may elicit quite different responses at their receptors compared with the basal state.