Assertion: adenosine's receptor | /r/CapableOf | mediate g protein
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text: The first non- rhodopsin GPCR structure to be obtained was the p 2 -adrenergic receptor in complex with an antibody fragment bound to the third intracellular loop (ICL) 3 - a critical domain of the receptor which mediates G protein coupling A higher resolution structure of the p 2 -AR was obtained by fusing T4 lysozyme into ICL355 and the same methodology was used to obtain the first structure of the adenosine A2A receptor (A2A- 4L)8.