Assertion: barbiturate's use | /r/HasSubevent | dependence
Facets:
Source sentences:
text: Continued use can also lead to dependence and withdrawal when use is abruptly reduced or stopped.
text: Sedative drugs are helpful for treating anxiety and sleep problems, but using them can lead to dependence or addiction.
text: Excessive use of the drug leads to tolerance, dependence, and withdrawal symptoms similar to those of barbiturates.
text: Frequent or prolonged use of Xanax can lead to dependence or addiction.