Assertion: acetaldehyde | /r/HasProperty | reactive compound
Facets:
value: highly
type: DEGREE
value: with both pharmacological and toxic properties
type: OTHER
value: unquestionably
type: MANNER
value: neuropharmacologically
type: MANNER
value: in summary
type: OTHER
value: in the oxidation of alcohols
type: TRANSITIVE-OBJECT
value: pharmacologically
type: MANNER
Source sentences:
text: Acetaldehyde is a highly reactive compound with a very short half-life and reacts with biogenic amines to produce condensation products known as tetrahydroisoquinolines (THIQs).
text: In summary, acetaldehyde is a pharmacologically active compound that acts either directly or through the formation of adducts to induce effects in both the periphery and the brain.
text: Acetaldehyde is very reactive and causes damage to DNA and proteins, and leads to the inflammation that causes the face to turn red when drinking alcohol.
text: Acetaldehyde is a neuropharmacologically active substance, which has reinforcing properties on its own and provokes, although at lower doses/concentrations than ethanol, some behavioral responses similar to its parent compound suggestive of the fact that it could be responsible of some of its effects (Correa et al., 2012).
text: Acetaldehyde is an active metabolite with a range of toxic and pharmacological effects, and many of the effects induced by direct acetaldehyde application mimic those of ethanol.
text: (A) Alcohol breakdown by the enzyme alcohol dehydrogenase (ADH) and by the microsomal ethanol–oxidizing system (MEOS) generates acetaldehyde, a reactive molecule that among other harmful effects interacts with cysteine, preventing it from being used to generate GSH (see panel B).
text: Acetaldehyde, malonaldehyde, and the other low-molecular-weight aldehydes included in this CIB are highly reactive intermediates in the oxidation of alcohols to acids [Henson 1959].
text: The most important enzyme involved in the breakdown of alcohol is called alcohol dehydrogenase, which converts alcohol into acetaldehyde, a highly reactive and toxic molecule that may play a crucial role in alcohol–related liver damage.
text: Metabolism of ethanol with ADH produces acetaldehyde, a highly reactive and toxic byproduct that may contribute to tissue damage and, possibly, the addictive process.
text: Since acetaldehyde is a very organ‐toxic and reactive compound, the systemic acetaldehydemia has been considered to be responsible for the carcinogenesis in this region.
text: Since acetaldehyde is a very organ‐toxic and reactive compound, the systemic acetaldehydemia has been considered to be responsible for the carcinogenesis in this region.
text: Although acetaldehyde unquestionably is an active compound with both pharmacological and toxic properties, researchers have not been able to conclusively establish that acetaldehyde can induce these effects in the living organism (i.e., in vivo) at the physiological concentrations obtained after alcohol consumption.