Assertion: barbiturate's effect | /r/HasProperty | determined a combination of the above
Facets:
value: mainly
type: OTHER
value: by the patients pattern of use
type: CAUSE
Source sentences:
text: The effects, severity, and duration appear to be slightly dose-dependent but are mainly determined by the patients pattern of use (taken as prescribed, taken in bulk doses, mixed with other drugs, a combination of the above, etc.), genetic predisposition to drug abuse, and a history of substance abuse all increase the patients risk of persistent discontinuation syndrome symptoms.