Assertion: caffeine | /r/CapableOf | cross the blood-brain barrier
Facets:
value: readily
type: MANNER
value: owing to its lipid solubility
type: CAUSE
Source sentences:
text: As a fat- and water-soluble molecule, caffeine readily crosses the blood-brain barrier where it constricts, or narrows, the blood vessels.
text: Because caffeine is both water- and lipid-soluble, it readily crosses the blood–brain barrier that separates the bloodstream from the interior of the brain.
text: Caffeine crosses the blood-brain barrier quickly (owing to its lipid solubility) although it can take up to 45 minutes for full ingestion through the gastro-intestinal tract.
text: When we drink a caffeinated beverage, the caffeine quickly crosses the blood-brain barrier—an interface of sorts between the brain and the body’s circulatory system, designed to protect the central nervous system from chemicals in the blood that might harm it—and proceeds to block the activity of a substance called adenosine.
text: Because caffeine is both water- and lipid-soluble, it readily crosses the blood–brain barrier that separates the bloodstream from the interior of the brain.
text: Caffeine is soluble in water and lipids, easily crosses the blood–brain barrier, and can be found in all body fluids, including saliva and cerebrospinal fluid.