Assertion: anesthetic's effect | /r/HasProperty | more pronounced
Facets:
value: in patients with poor
type: OTHER
Source sentences:
text: These effects could be more pronounced with concomitant use of Alfentanil HCl Injection and CYP2D6 and CYP3A4 inhibitors, particularly when an inhibitor is added after a stable dose of Alfentanil HCl Injection is achieved [see Warnings and Precautions ( 5.4 )].
text: (in addition to the increased CNS depressant, respiratory depressant, and hypotensive effects that may occur when an anesthetic is used concurrently with any CNS depressant, concurrent use of high doses of fentanyl or its derivatives with nitrous oxide may decrease heart rate and cardiac output; these effects may be more pronounced in patients with poor left ventricular function)