Assertion: amiodarone | /r/Causes | increase
Facets:
value: in thyroid follicular tumours
type: LOCATION
value: in both sexes
type: OTHER
value: in serum reverse t3
type: OTHER
value: at clinically relevant exposures
type: OTHER
value: in serum t4
type: OTHER
Source sentences:
text: In a 2-years carcinogenicity study in rats, amiodarone caused an increase in thyroid follicular tumours (adenomas and/or carcinomas) in both sexes at clinical relevant exposures.
text: Cordarone alters the results of thyroid-function tests, causing an increase in serum T4 and serum reverse T3, and a decline in serum T3 levels.
text: In a 2-years carcinogenicity study in rats, amiodarone caused an increase in thyroid follicular tumours (adenomas and/or carcinomas) in both sexes at clinically relevant exposures.