Assertion: adenosine's receptor | /r/HasProperty | β 2 ar
Facets:
Source sentences:
text: Efforts to elucidate the crystal structures of GPCRs bound to diffusible ligands have recently yielded structures for five class A (rhodopsin-like) GPCRs: the β 2 (1–7) and β 1 (8, 9) adrenergic receptors (β 2 AR and β 1 AR), the A 2A adenosine receptor (A 2A AR) (10), the CXCR4 chemokine receptor (11), and the D3 dopamine receptor (12).
text: All four agonist-bound structures adopted a conformation that was different from the inactive state, but that did not fully resemble the active state of the β 2 adrenergic receptor (β 2 AR) in complex with heterotrimeric G s (Rasmussen et al., 2011b), this conformation was therefore defined as the intermediate-active state (Lebon et al., 2011b).