Assertion: caffeine | /r/CapableOf | interact with the dopamine system
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text: Aside from its well-known effects on sleep and arousal, which are primarily mediated by antagonism of the adenosine A1 receptor, caffeine is also known to interact with the dopamine system to exert some of its behavioral effects (Cauli and Morelli, 2005; Fredholm and Svenningsson, 2003).