Assertion: apoptosis | /r/HasProperty | intrinsic pathway
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Source sentences:
text: Genotoxic stress: hypoxia, heat, radiation etc… leading to DNA damage & activation of P53 gene causing apoptosis (intrinsic pathway).
text: From this large body of work it is clear that apoptosis is induced by a range of stimuli that activate two major cell death signaling pathways: the intrinsic pathway mainly controlled by Bcl-2 protein family members and the extrinsic pathway activated by death receptors of the tumor necrosis factor receptor superfamily (Fig. 1).