Assertion: barbiturate | /r/HasAspect | narrow therapeutic index
Facets:
value: very
type: DEGREE
Source sentences:
text: Barbiturates are an older class of medicine that used to be used for these indications as well; however, barbiturates have a narrow therapeutic index (window of effectiveness before toxicity occurs), and are more likely to cause respiratory depression, coma and death, and are very rarely used nowadays.
text: Since barbiturates have a very narrow therapeutic index, patients can easily develop side effects and toxicity.