Assertion: acetaminophen's use | /r/HasSubevent | a withdrawal syndrome
Facets:
value: in a patient
type: OTHER
Source sentences:
text: Concomitant use of hydrocodone bitartrate and acetaminophen tablets with CYP3A4 inducers or discontinuation of an CYP3A4 inhibitor could decrease hydrocodone plasma concentrations, decrease opioid efficacy or, possibly, lead to a withdrawal syndrome in a patient who had developed physical dependence to hydrocodone.