Assertion: antibody's domain | /r/HasProperty | vh
Facets:
Source sentences:
text: Each heavy chain has a variable domain (VH), and three or four constant domains (CH1, CH2, CH3, CH4).
text: Although a vast number of recombinant antibody structures has been proposed , the single chain (scFv) and the single domain (VHH, VH, and NAR V) formats are the most widespread for both research and industrial applications [2–4]. Recombinant antibodies seem particularly promising as immunoconjugates  and for activating the biosensor chip surfaces for detecting specific antigens .
text: Importantly, we find that single-domain (V H H) antibodies specific for the α-synuclein protein (whose aggregation is associated with Parkinson’s disease) with the greatest gains in affinity (>5-fold) have several (four to six) CDR mutations.
text: Since display and screening were carried out with single-chain fragments, all mAb variants are identical in their constant domains, with all mutations located in the variable domains (VH and VL).