Assertion: alkaloid's effect | /r/CapableOf | necessitate dosing frequency of 6 to 8
Facets:
value: with a consequent risk
type: OTHER
Source sentences:
text: Although reductions in intraocular pressure have been reported, the effect lasts only 3 to 4 hours, necessitating a dosing frequency of 6 to 8 times a day with a consequent risk of initiating substance abuse among users.