Assertion: antibody's region | /r/HasProperty | cdrs
Facets:
Source sentences:
text: These loops are referred to as the complementarity-determining regions (CDRs).
text: Rituximab Humanised Murine complementarity-determining regions (CDRs)
text: The germline identity and the complementarity determining regions (CDRs) of the sequenced variable regions of the quenching mAbs were identified with IMGT (the international ImMunoGeneTics information system http://www.imgt.org) and
text: Variants of an antibody can be made via amino-acid substitutions within the framework regions or the complementary-determining regions (CDRs).
text: (C) Close-up view of the antibody complementarity-determining regions (CDRs) and the BACE1 epitope.
text: Our approach first uses computational and experimental alanine scanning mutagenesis to identify sites in the complementarity-determining regions (CDRs) that are permissive to mutagenesis while maintaining antigen binding.
text: First, while it is possible to use saturation mutagenesis to evaluate every possible single mutation in antibody complementarity-determining regions (CDRs), single mutations typically do not result in large gains in affinity (1, 3, 24).