Assertion: antibody's effect | /r/CapableOf | promote new interactions
Facets:
value: between the antigen
type: OTHER
value: between wild-type cdr residues
type: OTHER
Source sentences:
text: Computational modeling reveals that improvements in affinity are generally not due to direct interactions involving CDR mutations but rather due to indirect effects that enhance existing interactions and/or promote new interactions between the antigen and wild-type CDR residues.