Assertion: aortic valve's cusp | /r/CapableOf | increase mechanical strain
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Source sentences:
text: Calcium deposition leads to stiffening of the cusps, which increases mechanical strain and injury and further induces activation of the Wnt/β-catenin pathway, eventually leading to even more osteoblastic differentiation of VICs through ENPP (ectonucleotide pyrophosphatase/phosphodiesterase 1; Figures 1 and 2).