Assertion: apoptosis | /r/HasProperty | induced via growth factor deprivation
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text: In contrast to Ca2+ or oxidant-induced PT-pore opening, less is known about the role of pH when apoptosis is induced via mitochondria-dependent pathways where PT-pore opening is a later event and where apparent hyperpolarization rather than depolarization is observed (e.g Bax; staurosporine; anticancer drugs; irradiation; growth factor deprivation).