Assertion: apoptosis | /r/HasProperty | induced by cytotoxic drugs
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text: A heptapeptide representing the N-terminus of mature Smac/DIABLO, which is essential for binding to XIAP, was reported to promote caspase activation and to sensitize various tumor cell lines and also primary patients' derived tumor cells for apoptosis induced by death-receptor ligation or cytotoxic drugs (Fulda et al., 2002).