Assertion: amiodarone | /r/CapableOf | increase flecainide plasma levels
Facets:
Source sentences:
text: Given that flecainide is mainly metabolised by CYP 2D6, by inhibiting this isoenzyme, amiodarone may increase flecainide plasma levels; it is advised to reduce the flecainide dose by 50% and to monitor the patient closely for adverse effects.