Assertion: intrinsic apoptosis | /r/HasProperty | huang
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text: The role of BH3-only proteins as the initiators of intrinsic apoptosis (Huang & Strasser, 2000) has led to the development of small molecules that mimic the behavior of BH3-only proteins to antagonize prosurvival Bcl-2 proteins for initiation of cell death in diseases where expression of these proteins prevents appropriate cell death (Lessene, Czabotar, & Colman, 2008).