Assertion: multiple displacement amplification | /r/CapableOf | involve the binding of random hexamers
Facets:
value: to denatured dna
type: TRANSITIVE-OBJECT
Source sentences:
text: Furthermore, these techniques have been found to exhibit incomplete genome coverage and amplification bias — where a sequence is overrepresented in the amplified DNA due to preferential binding of the primers to specific regions (see figure Highly representative amplification using MDA ).REPLI-g uses isothermal genome amplification, termed Multiple Displacement Amplification (MDA), which involves the binding of random hexamers to denatured DNA followed by strand displacement synthesis at a constant temperature using the enzyme Phi 29 polymerase.