Assertion: atp | /r/CapableOf | act as hydrotrope
Facets:
value: in a classical hydrotrope assay
type: OTHER
Source sentences:
text: The authors found that ATP at concentrations found in cells could act as a hydrotrope to help solubilize hydrophobic proteins.
text: 2A), we sought to explore whether ATP might act like a hydrotrope in a classical hydrotrope assay, in which the solubility of a hydrophobic compound such as fluorescein diacetate (FDA) in water is quantified as a function of hydrotrope concentration (15).
text: The data showing that the hydrophobic adenosine ring of ATP strongly enhances the effect of the charged tripolyphosphate moiety on protein stability are consistent with the hypothesis that ATP also acts as a hydrotrope, where the aromatic group could form dynamic clusters around hydrophobic solute molecules (17, 19, 21).