Assertion: naïve antibody | /r/HasProperty | leads
Facets:
value: with few exceptions
type: OTHER
value: to specificity
type: PURPOSE
Source sentences:
text: Past studies have suggested that, with few exceptions (29, 65, 66), naïve antibodies are highly flexible and maturation leads to improved affinity and specificity through the optimization and rigidification of the antibody paratope, and in particular the CDR-H3 loop (22, 27, 28, 31–33).