Assertion: belladonna's use | /r/HasSubevent | coma
Facets:
Source sentences:
text: Concomitant use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death [see Warnings and Precautions (5.4), Drug Interactions (7)]. Reserve concomitant prescribing of Belladonna and Opium Suppositories and benzodiazepines or other CNS depressants for use in patients for whom alternative treatment options are inadequate.