Assertion: amiodarone's metabolite | /r/HasAspect | larger vd
Facets:
value: than n-desmethylamiodarone
type: OTHER
value: than 49–51]. amiodarone
type: OTHER
value: than the parent drug
type: OTHER
Source sentences:
text: Major metabolite of amiodarone, N-desmethylamiodarone, is not only pharmacologically active but has a longer elimination half-life and a larger VD than the parent drug [1, 10, 49–51]. Amiodarone and N-desmethylamiodarone may be detected even months after stopping the drug  as amiodarone accumulates in lipid reservoirs and is released slowly from these reservoirs.