  The study is based on a principle of laser physics so that a (coherent) laser
light whose wavelength is shorter than a feature under inspection (like
sub-cellular component) can interact with such specific feature (or textural
features) and generates laser speckle patterns which can characterize those
specific features. By the method we have managed to detect differences at
sub-cellular scales such as genetic modification, cellular shape deformation,
etc. with 87% accuracy. In this study red laser is used whose wavelength (6.5
microns) is shorter than a plant cell (~60 microns) that is suitable to
interact with sub-cellular features. The work is assumed to be an initial stage
of further application on human cellular changes observation that would be
utilized for development of more accurate methods such as better drug delivery
assessments, systemic diseases early diagnosis, etc.
