  Nanoscale wireless networks are expected to revolutionize a variety of
domains, with significant advances conceivable in in-body healthcare. In
healthcare, these nanonetworks will consist of energy-harvesting nanodevices
passively flowing through the bloodstream, taking actions at certain locations,
and communicating results to more powerful Body Area Network (BAN) nodes.
Assuming such a setup and electromagnetic nanocommunication in the Terahertz
(THz) frequencies, we propose a network architecture that can support
fine-grained localization of the energy-harvesting in-body nanonodes, as well
as their two-way communication with the outside world. The main novelties of
our proposal lie in the introduction of location-aware and Wake-up Radio
(WuR)-based wireless nanocommunication paradigms, as well as Software-Defined
Metamaterials (SDMs), to THz-operating energy-harvesting in-body nanonetworks.
We argue that, on a high level, the proposed architecture can handle (and
actually benefits from) a large number of nanonodes, while simultaneously
dealing with a short range of THz in-body propagation and highly constrained
nanonodes.
