  This paper investigates prefrontal cortex (PFC) functional connectivity based
on synchronized electrical and hemodynamic responses associated with mental
stress. The electrical response was based on alpha rhythmic of
Electroencephalography (EEG) signals and the hemodynamic responses were based
on the mean concentrations of oxygenated and deoxygenated hemoglobin measured
using functional Near-Infrared Spectroscopy (fNIRS). The aim is to explore the
effects of stress on the inter and intra hemispheric PFC functional
connectivity at narrow and wide frequency bands with 8- 13 Hz in EEG and
0.009-0.1Hz in fNIRS signals. The results demonstrated significantly reduce in
the functional connectivity on the dorsolateral PFC within the inter and intra
hemispheric PFC areas based in EEG alpha rhythmic and fNIRS oxygenated and
deoxygenated hemoglobin. The statistical analysis further demonstrated right
dorsolateral dominant to mental stress.
