  In single particle analysis (SPA), the task is to recover the scattering
potential of a macromolecular structure from cryo-electron microscope images of
many copies of the structure in unknown orientations. The idealized, noise-free
SPA inverse problem has been shown to be uniquely solvable - up to hand - when
the forward model is based on the ray transform. More accurate forward models
take the non-zero curvature of the Ewald sphere into account. We analyze an
Ewald sphere corrected forward model for SPA and use the diffraction slice
theorem to prove that the corresponding inverse problem is uniquely solvable,
including the hand of the structure.
