  Since their introduction in Abadie and Gardeazabal (2003), Synthetic Control
(SC) methods have quickly become one of the leading methods for estimating
causal effects in observational studies with panel data. Formal discussions
often motivate SC methods by the assumption that the potential outcomes were
generated by a factor model. Here we study SC methods from a design-based
perspective, assuming a model for the selection of the treated unit(s), e.g.,
random selection as guaranteed in a randomized experiment. We show that SC
methods offer benefits even in settings with randomized assignment, and that
the design perspective offers new insights into SC methods for observational
data. A first insight is that the standard SC estimator is not unbiased under
random assignment. We propose a simple modification of the SC estimator that
guarantees unbiasedness in this setting and derive its exact,
randomization-based, finite sample variance. We also propose an unbiased
estimator for this variance. We show in settings with real data that under
random assignment this Modified Unbiased Synthetic Control (MUSC) estimator can
have a root mean-squared error (RMSE) that is substantially lower than that of
the difference-in-means estimator. We show that such an improvement is weakly
guaranteed if the treated period is similar to the other periods, for example,
if the treated period was randomly selected. The improvement is most likely to
be substantial if the number of pre-treatment periods is large relative to the
number of control units.
