  Self-Immolative Chemistry is based on the cascade of disassembling reactions
triggered by the adequate stimulation and leading to the sequential release of
the smaller constituent elements. This review will focus on the possibilities
that this type of chemistry offers to nanomedicine research, which is an area
where the stimuli responsive behavior is always targeted. There are some
examples on the use of self-immolative chemistry for prodrugs or nanoparticles
for drug delivery, but there is still an exciting land of opportunities waiting
to be explored. This review aims at revising what has been done so far, but,
most importantly, it aims at inspiring new research of self-immolative
chemistry on nanomedicine.
