  We study numerically the effect of thermal fluctuations and of variable
fluid-substrate interactions on the spontaneous dewetting of thin liquid films
and on the subsequent coarsening of droplets. To this aim, we use a recently
developed lattice Boltzmann method for thin liquid film flows, equipped with a
properly devised stochastic term. While it is known that the actual inclusion
of thermal fluctuations yields shorter rupture times, we show that this is a
general feature of hydrophilic substrates with equilibrium contact angles
$\theta_{\text{eq}} < \pi/2$. Interestingly, the ratio between rupture times
does as well depend on $\theta_{\text{eq}}$, i.e. more wettable substrates show
a larger deviation in the rupture time. Finally, we discuss the case of a
fluctuating thin film on a chemically patterned substrate with and without
smooth wettability gradients.
