  The analysis of plaque deposits in the coronary vasculature is an important
topic in current clinical research. From a technical side mostly new algorithms
for different sub tasks - e.g. centerline extraction or vessel/plaque
segmentation - are proposed. However, to enable clinical research with the help
of these algorithms, a software solution, which enables manual correction,
comprehensive visual feedback and tissue analysis capabilities, is needed.
Therefore, we want to present such an integrated software solution. It is able
to perform robust automatic centerline extraction and inner and outer vessel
wall segmentation, while providing easy to use manual correction tools. Also,
it allows for annotation of lesions along the centerlines, which can be further
analyzed regarding their tissue composition. Furthermore, it enables research
in upcoming technologies and research directions: it does support dual energy
CT scans with dedicated plaque analysis and the quantification of the fatty
tissue surrounding the vasculature, also in automated set-ups.
