  We compute the density dependence of the quark condensate and how it changes
under the influence of isospin-asymmetric nuclear matter. This is achieved by
the calculation of the relevant Feynman diagrams using in-medium chiral
perturbation theory. We find that the absolute value of the quark condensate
decreases in nuclear matter by around $35\%$ at normal nuclear density, in
agreement with previous model-independent calculations. We also present an
quantitative estimation of the difference of up- and down quark in-medium
condensates.
