Premise: San Francisco ( initials SF ) ( [ sæn_frənˈsɪskoʊ ] , Spanish for Saint Francis ; Spanish : [ san franˈsisko ] ) , officially the City and County of San Francisco , is the cultural , commercial , and financial center of Northern California . San Francisco is the fourth-most populous city in California , after Los Angeles , San Diego , and San Jose , and the 13th-most populous city in the United States -- with a census-estimated 2016 population of 870,887 . The California Gold Rush of 1849 brought rapid growth , making it the largest city on the West Coast at the time . After three-quarters of the city was destroyed by the 1906 earthquake and fire , San Francisco was quickly rebuilt , hosting the Panama-Pacific International Exposition nine years later .
Hypothesis: San Francisco is a city.
Label: ENTAILMENT