Premise: Lyme disease . The most common sign of infection is an expanding area of redness on the skin , known as erythema migrans , that begins at the site of a tick bite about a week after it has occurred . Other early symptoms may include fever , headache and feeling tired . Diagnosis is based upon a combination of symptoms , history of tick exposure , and possibly testing for specific antibodies in the blood . In those who develop persistent symptoms , long-term antibiotic therapy has not been found to be useful .
Hypothesis: Lyme disease has no symptoms.
Label: CONTRADICTION