Premise: Anti-nuclear antibody . There are many subtypes of ANAs such as anti-Ro antibodies , anti-La antibodies , anti-Sm antibodies , anti-nRNP antibodies , anti-Scl-70 antibodies , anti-dsDNA antibodies , anti-histone antibodies , antibodies to nuclear pore complexes , anti-centromere antibodies and anti-sp100 antibodies .
Hypothesis: A cause of anti-nuclear antibodies are are anti-sp100 antibodies.
Label: ENTAILMENT