Question: how does bpg help at high altitudes?
Answer: 2,3 Bisphosphoglycerate (2,3-BPG) stabilizes the T- (taut; oxygen unbound) form of haemoglobin thereby reducing its affinity to bind to oxygen. 2,3-BPG is found to be elevated in people living at high altitudes. ... However, haemoglobin content also increases so that higher amounts of oxygen can be captured.