Question: is igm cold or warm?
Answer: Antibody Mediated Hemolysis. In autoimmune hemolytic anemia (AIHA) RBCs are destroyed by antibodies made by a person against their own RBCs. AIHA is divided into two types: an IgG or "warm" type (optimally active at 37oC) and an IgM or "cold" type (optimally active at 4oC).