Question: what is the difference between rna polymerase core enzyme and holoenzyme?
Answer: E. coli RNA Polymerase Core Enzyme consists of 5 subunits designated α, α, β', β, and ω. The enzyme is free of sigma factor and does not initiate specific transcription from bacterial and phage DNA promoters. ... coli RNA Polymerase Holoenzyme is the core enzyme saturated with sigma factor 70.