Question: is duloxetine used for migraines?
Answer: In fact, antidepressants with dual mechanisms (serotonin and norepinephrine) are more effective for pain and headache. Another similar medication is duloxetine (Cymbalta), with typical doses being 30 mg to 60 mg daily. Cymbalta has several pain indications, but is probably more effective for moods than for headache.