Question: what is the most powerful weapon in anime?
Answer: 1 Super Tengen Toppa Gurren Lagann. The Super Tengen Toppa Gurren Lagann stands at the top of the list as the single most powerful weapon and mecha in existence.
2 Sword Of Rupture. ... 
3 Death Note. ... 
4 Spear Of Longinus. ... 
5 The Dragon Slayer. ... 
6 Neo Armstrong Cyclone Jet Armstrong Cannon. ... 
7 Tessaiga. ... 
8 Dimension Sword. ...