Question: what is the difference between lysosome and endolysosome?
Answer: Arguably, lysosomes are vesicles that can store mature lysosomal enzymes and deliver them to a late endosomal compartment when needed. The resulting organelle is called the hybrid organelle or endolysosome. Lysosomes bud off the hybrid organelle in a process referred to as lysosome re-formation (Bright et al. 1997).