Question: how long does the first herpes outbreak last with valtrex?
Answer: It can take up to 10 days (or, in some cases, even longer) for herpes blisters to heal even with valacyclovir treatment. This makes it important to start treatment as soon as you notice herpes symptoms. In some cases, your doctor might prescribe valacyclovir for a longer period than 10 days or at a different dosage.