Question: is tiotropium a lama or sama?
Answer: O1. 1.2 Short-acting muscarinic antagonist (SAMA) Bronchodilators such as ipratropium, tiotropium, glycopyrronium, aclidinium and umeclidinium are not 'anticholinergics' since they are unable to antagonize the effects of acetylcholine on nicotinic receptors. They only block the muscarinic effects of acetylcholine.