Question: what is the most powerful weapon in bloodborne?
Answer: 1 Ludwig's Holy Blade. Everything the Hunter Axe does, Ludwig's Holy Blade does (arguably) better.
2 Whirligig Saw. The Whirligig Saw is one of the most simple, brutal, and horrifying weapons in the game. ... 
3 Hunter Axe. ... 
4 Holy Moonlight Sword. ... 
5 Rakuyo. ... 
6 Blade Of Mercy. ... 
7 Kos Parasite. ... 
8 Burial Blade. ...