Question: is fexofenadine the same as diphenhydramine?
Answer: Are Benadryl and Allegra the Same Thing? Benadryl (diphenhydramine) and Allegra (fexofenadine hydrochloride) are antihistamines used to treat allergic symptoms of seasonal allergic rhinitis (sneezing, runny nose, itchy or watery eyes), and hives.