Question: what is the difference between a needle biopsy and a core biopsy?
Answer: Needles used in a core biopsy are slightly larger than those used in FNA. They remove a small cylinder of tissue (about 1/16 inch in diameter and 1/2 inch long). The core needle biopsy is done with local anesthesia (drugs are used to make the area numb) in the doctor's office or clinic.