Question: how long does it take to adjust to zantac?
Answer: If you are treating an ulcer, Zantac may take up to 8 weeks for the ulcer to heal. You should notice improvement within 6 weeks. If you are taking Zantac for gastric reflux you should notice improvement within 1 to 2 weeks. If you are taking Zantac for heartburn you should notice improvement within 24 hours.