Question: does sickle cell anemia cause low hemoglobin?
Answer: This defect causes the hemoglobin protein to stick together and form stiff fibers. These fibers distort the shape of the red blood cells and make them more fragile. The hemoglobin in sickle cell anemia patients is called hemoglobin S, whereas those unaffected by the disease have the hemoglobin A form of the molecule.