Question: what are the three categories of loss-of-function mutations quizlet?
Answer: base substitution. change the base of a single DNA nucleotide.
transition. base substitution in which a purine replace a pyrimidine or a pyrimidine.
transversion. ... 
insertion. ... 
deletion. ... 
frameshift mutation. ... 
in-frame deletion or insertion. ... 
expanding trinucleotide repeats.