Question: how long do you have to wait between tylenol and motrin?
Answer: Doses of acetaminophen (e.g., Tylenol, Tempra) should be given at least four hours apart. Doses of ibuprofen (e.g., Advil, Motrin) should be given at least six hours apart. There are limits on how much of each medication can be given in a 24-hour period.