Question: is karin related to kushina?
Answer: Yes, nagato, karin, naruto, hashirama's wife mito and kushina are all related (tsunade senju and her brother nawaki are technically descendants of the uzumaki clan because of their grandmother). ... Naruto's mother, Kushina Uzumaki, is a member of the Uzumaki clan. Karin is also a member of this Uzumaki.