Question: is imiquimod the same as fluorouracil?
Answer: Are Efudex and Aldara, Zyclara the Same Thing? Efudex (fluorouracil) topical and Aldara, Zyclara (imiquimod) topical (for the skin) are used to treat scaly overgrowths of skin (actinic or solar keratoses). Efudex and Aldara, Zyclara may also be used in the treatment of superficial basal cell carcinoma.