Question: how long does a whole chicken take to cook at 375?
Answer: Roast chicken for 30 minutes. Reduce temperature to 375°F. Continue to roast, basting occasionally and adding water as needed, for 1 1/2 to 2 1/2 hours or until pop-up timer pops up and thermometer registers 180°F. The juices should run clear with no hint of pink in meat.