Question: what is a major distinction between anaphase i and anaphase ii?
Answer: what's the difference between anaphase I and anaphase II? products of one are the reactants for the other. ... anaphase 2 is like mitosis because separation and splitting up centromere.In anaphase I the homologous chromosomes separate, in anaphase II the centromere splits, in mitosis anaphase the centromere splits.