Question: what is the best pain relief for severe toothache?
Answer: Acetylsalicylic Acid (Aspirin) This is one of the most well-known and most widely used pain killers in the world. ... 
Ibuprofen or Ketoprofen. Many consider this to be the best over the counter painkillers for dental pain. ... 
Acetaminophen or Paracetamol. ... 
Naproxen. ... 
Co-codamol. ... 
Diclofenac. ... 
Homeopathic options.