Question: what is the difference between dr and er?
Answer: Divalproex DR (delayed-release) is the equivalent of Depakote. In this case “delayed-release” simply means that it is enteric coated, and thus the release of the medicine is “delayed” until it passes through the stomach. ... Divalproex ER (extended-release) is the equivalent of Depakote ER. Usually dosed once daily.