Question: what the best over the counter medicine for sinus drainage?
Answer: Try a pain reliever such as acetaminophen or ibuprofen to relieve facial pain and headache. Use a nasal spray, gel, or drops to help a stuffy nose. There's a decongestant kind (such as Afrin, Dristan, or Neo-Synephrine) and a steroid spray kind (such as Nasacort).