Question: what are two differences between adenine and guanine?
Answer: Both adenine and guanine are purines. ... The main difference between adenine and guanine is that adenine contains an amine group on C6, and an additional double bond between N1 and C6 in its pyrimidine ring whereas guanine contains an amine group on C2 and a carbonyl group on C6 in its pyrimidine ring.