Question: is suphedrine pe an antihistamine?
Answer: What is Sudafed PE Sinus & Allergy? Chlorpheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages.