Question: can pioglitazone cause bladder cancer?
Answer: Meta‐analysis of adjusted estimates from 19 studies that provided the data of bladder cancer risk showed that ever use of pioglitazone was associated with significantly increased risk of bladder cancer compared with never‐users (OR, 1.13; 95% CI, 1.03 to 1.25), with moderate between‐study heterogeneity (I 2 = 31.3%; ...