Question: endorphins and enkephalins are neuropeptides that?
Answer: Endorphins and Enkephalins Endorphins, enkephalins, and dynorphin are powerful peptide or polypeptide analgesics. Their analgesic action requires binding to opiate receptors on nerve cells. ... Enkephalins act to attenuate substance P release in the dorsal horn of the spinal cord and inhibit afferent pain fibers.