Question: is trizma the same as tris hcl?
Answer: Is Product T3253,Trizma® hydrochloride, the same as Tris buffer? No. Trizma HCl in solution at 0.05 M will produce a pH of approximately 4.7, but will have little if any buffering capacity. Trizma Base in solution at 0.05 M will produce a pH of approximately 10.4, but will have little if any buffering capacity.