Question: what is the best over the counter pain medication for sciatica?
Answer: Medications for Relief of Pain From Sciatica Oral medications include: Over-the-counter pain relievers such as acetaminophen, aspirin, or NSAIDs (such as ibuprofen [Advil, Motrin], ketoprofen, or naproxen [Aleve]) Prescription muscle relaxants to ease muscle spasms. Antidepressants for chronic low back pain.