Question: can bxo lead to cancer?
Answer: BXO and penile squamous cell carcinoma The risk of malignant change in patients with BXO has been quantified in a few studies. Depasquale et al. reported a 2% rate in a cohort of 522 patients [3]. Nasca et at. calculated a 5.8% risk with a mean range of 17 years from diagnosis to malignant transformation.