Question: what is the difference between adapalene and tretinoin?
Answer: Adapalene is an addition to the arsenal of topical retinoids. ... Accordingly, numerous clinical trials have compared adapalene and tretinoin in the management of acne vulgaris and concluded that tretinoin 0.05% gel exhibits a greater anti-acne efficacy than adapalene 0.1% gel, but has higher skin irritation potential.