Question: what is the best over the counter medicine for irritable bowel syndrome?
Answer: Over-the-Counter (OTC) Medicines Your doctor may suggest trying OTC diarrhea medicines such as bismuth subsalicylate (Kaopectate, Pepto-Bismol) and loperamide (Imodium) for relief. Researchers have found these drugs can help slow diarrhea, but they won't help with other IBS symptoms like belly pain or swelling.