Question: can zofran help with diarrhea?
Answer: Ondansetron Works for Diarrhea-Predominant Irritable Bowel Syndrome. This 5-HT3 receptor antagonist improved stool consistency and symptoms, with a low frequency of severe constipation. Ondansetron is a 5-hydroxytryptamine 3 receptor antagonist (5-HT3RA) used for the treatment of nausea and vomiting.