Question: what is the best over-the-counter medication for arthritis pain?
Answer: Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) NSAIDs work similarly to aspirin to ease joint pain. Although there are more than a dozen NSAIDs available by prescription, only two are currently available OTC: ibuprofen (Advil, Motrin IB) and naproxen sodium (Aleve).