Question: how many calories in a large slice of cheesecake?
Answer: Cheesecake. Cheesecake is a year-round favorite, but this decadent dessert isn't doing your waistline any favors. A typical piece of cheesecake contains more than 250 calories and a whopping 18 grams of fat. The danger in this dessert is the amount of saturated fat hiding in each slice — at almost 10 grams!