Question: what is the difference between methylphenidate la and cd?
Answer: Metadate CD is a once-a-day capsule with biphasic release; initially there is a rapid release of methylphenidate, then a continuous-release phase. Metadate ER, on the other hand, is a tablet given two to three times per day. Metadate ER may be titrated to eliminate the need for midday dosing.