Question: what is the difference between primary biliary cholangitis and sclerosing cholangitis?
Answer: Only PSC comes with a seriously increased risk for colorectal cancer and cholangiocarcinoma. Furthermore, PBC has a 90% predominance of women, whereas PSC affects two men for every woman. PBC can be diagnosed through a combination of blood tests and liver biopsy, while PSC is most often diagnosed by MRCP.