Question: are metoprolol and sotalol the same?
Answer: Both agents produced a lower mean heart rate than placebo over 24 h (P < 0.001 for all), while sotalol produced a lower mean heart rate than metoprolol during the daytime (P < 0.01). Conclusion: Sotalol is a safe and effective agent for control of heart rate in digitalized patients with atrial fibrillation.