Question: what is the best over-the-counter medication for upset stomach?
Answer: Bismuth subsalicylate, the active ingredient in OTC medications like Kaopectate® and Pepto-Bismol™, protects your stomach lining. Bismuth subsalicylate is also used to treat ulcers, upset stomach and diarrhea. Other medicines include cyclizine, dimenhydrinate, diphenhydramine, and meclizine.