Question: what is the best treatment for severe osteoarthritis?
Answer: Nonsteroidal anti-inflammatory drugs (NSAIDs). Over-the-counter NSAIDs , such as ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve, others), taken at the recommended doses, typically relieve osteoarthritis pain. Stronger NSAIDs are available by prescription.