Question: how long does it take for nortriptyline to take effect for pain?
Answer: Long story short on a very low-dose 10 mg of nortriptyline I noticed about 20% pain relief the next day. I've been on the medication for about two months and now I have about a 30% reduction of pain. A bonus side effect is that my periods are not nearly as painful and also I don't have to urinate as much as I used to.