Question: is ibrutinib a monoclonal antibody?
Answer: Ibrutinib has been studied in combination with ofatumumab in patients with relapsed/refractory CLL. Ofatumumab is a fully humanized anti-CD20 monoclonal antibody that is approved for the treatment of CLL refractory to fludarabine. As a single agent, it has a response rate of 45% [24].