tokens: The median dissociation constant ( Kd ) was similar in all three groups of patients and in healthy women ( mean +/- S.D. ( range ) : PHP , 1.2 +/- 1.0 ( 0.2-4 ) x 10 ( -10 ) M ; SH , 0.6 +/- 0.4 ( 0.2-1.2 ) x 10 ( -10 ) M ; RT , 1.1 +/- 0.5 ( 0.4-1.9 ) x 10 ( -10 ) M ; controls , 1.0 +/- 0.6 ( 0.3-2.6 ) x 10 ( -10 ) M ) . However , the maximal binding capacity ( Nmax ) was significantly enhanced in PHP ( 3.9 +/- 1.9 ( 1.3-7.6 ) fmol/10 ( 7 ) cells vs. 2.3 +/- 0.9 ( 1.1-4.4 ) fmol/10 ( 7 ) cells in controls ; P = 0.0006 ) and decreased in SH ( 0.8 +/- 0.5 ( 0.2-1.6 ) fmol/10 ( 7 ) cells vs. 2.3 +/- 0.9 ( 1.1-4.4 ) fmol/10 ( 7 ) cells in controls ; P = 0.0001 ) , whereas no changes were seen in RT ( 2.3 +/- 0.7 ( 1.2-3.3 ) fmol/10 ( 7 ) cells vs. 2.3 +/- 0.9 ( 1.1-4.4 ) fmol/10 ( 7 ) cells in controls ) .