tokens: In addition to its use as a stabilizer / rigidifier of membranes , cholesteryl hemisuccinate , tris salt ( CS ) administration has also been shown to protect rats from the hepatotoxic effects of carbon tetrachloride ( CCl4 ). To further our understanding of the mechanism of CS cytoprotection , we examined in rats and mice the protective abilities of CS and the non - hydrolyzable ether form of CS , gamma-cholesteryloxybutyric acid , tris salt ( CSE ) against acetaminophen -, adriamycin -, carbon tetrachloride -, chloroform - and galactosamine - induced toxicity .