tokens: Chronic FK506 nephropathy consisted of rough and foamy tubular vacuolization ( 5 biopsies ), arteriolopathy ( angiodegeneration of the arteriolar wall ; 20 biopsies ), focal segmental glomerulosclerosis ( 4 biopsies ) and the striped form of interstitial fibrosis ( 11 biopsies ). The serum creatinine levels of patients in the mild - type chronic FK506 nephropathy group , which included 7 episode biopsies , were statistically higher than those in the minimum - type chronic FK506 - nephropathy group ( P < 0 .