tokens: MATERIALS AND METHODS : From November 2005 to September 2007 , 8 patients ( 5 men and 3 women ) were diagnosed as having metronidazole - induced encephalopathy ( age range ; 43 - 78 years ). They had been taking metronidazole ( total dosage , 45 - 120 g ; duration , 30 days to 2 months ) to treat the infection in various organs .