tokens: NRA0160 has negligible affinity for the human cloned dopamine D3 receptor ( Ki = 39 nM ), rat serotonin ( 5-HT ) 2A receptors ( Ki = 180 nM ) and rat alpha1 adrenoceptor ( Ki = 237 nM ). NRA0160 and clozapine antagonized locomotor hyperactivity induced by methamphetamine ( MAP ) in mice .