tokens: The results indicated that concomitant treatment with gum Arabic and GM significantly increased creatinine and urea by about 183 and 239 %, respectively ( compared to 432 and 346 %, respectively , in rats treated with cellulose and GM ), and decreased that of cortical GSH by 21 %( compared to 27 % in the cellulose plus GM group ) The GM - induced proximal tubular necrosis appeared to be slightly less severe in rats given GM together with gum Arabic than in those given GM and cellulose .