tokens: 5 mg / kg ). The animals that had experienced cyclic sucrose and chow were hyperactive in response to amphetamine compared with four control groups ( ad libitum 10 % sucrose and chow followed by amphetamine injection , cyclic chow followed by amphetamine injection , ad libitum chow with amphetamine , or cyclic 10 % sucrose and chow with a saline injection ). These results suggest that a diet comprised of alternating deprivation and access to a sugar solution and chow produces bingeing on sugar that leads to a long lasting state of increased sensitivity to amphetamine , possibly due to a lasting alteration in the dopamine