Discovery of (R)-N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide [(R)-AS-1], a novel orally bioavailable EAAT2 modulator with drug-like properties and potent antiseizure activity in vivo
Authors: Abram, M.; Jakubiec, M.; Reeb, K.; Cheng, M. H.; Gedschold, R.; Rapacz, A.; Mogilski, S.; Socała, K.; Nieoczym, D.; Szafarz, M.; Latacz, G.; Szulczyk, B.; Kalinowska-Tłuścik, J.; Gawel, K.; Esguerra, C. V.; Wyska, E.; Müller, C. E.; Bahar, I.; Fontana, A. C. K.; Wlaź, P.; Kamiński, R. M.; Kamiński, K.
Published in: Journal of Medicinal Chemistry
Publication type: article
Subject areas: Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics
SJR best quartile: Q1