Spreadsheet: 1bfbcab2-3a06-4711-a580-4e28ede10493
Sheet: Sheet1

Supplementary table S2: DUX4 induced deregulated genes overlapping between C2C12 and human myoblasts | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6 | Unnamed: 7 | Unnamed: 8
Same direction:
mouse [NAME] | human [NAME] | mouse Symbol | human Symbol | human [NAME] | C2C12 LogFC | C2C12 FDR | Human myo LogFC | Human myo [NAME]
238330 | 64207 | 6430527G18Rik | IRF2BPL | interferon regulatory factor 2 binding protein-like | -1.68330608408873 | 1.2618363448339e-05 | -1.47638748656283 | 3.63698299451777e-12
19252 | 1843 | Dusp1 | DUSP1 | dual specificity phosphatase 1 | -1.68093939445947 | 2.44307928738029e-07 | -2.23831925210993 | 8.21927932444033e-15
27273 | 5166 | Pdk4 | PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | -1.59253011085236 | 9.48552941259172e-07 | -1.52095914770664 | 1.24702558412073e-09
16362 | 3659 | Irf1 | IRF1 | interferon regulatory factor 1 | -1.56040283364652 | 4.97550066300571e-07 | -2.64332853226495 | 6.77090092271334e-15
14200 | 2274 | Fhl2 | FHL2 | four and a half LIM domains 2 | -1.39383691622257 | 6.06070041682027e-07 | -1.71304115630424 | 4.9678745925809e-13
16477 | 3726 | [NAME] | [NAME] | jun B proto-oncogene | -1.38370908383998 | 8.14570829800854e-07 | -1.06337010552994 | 1.77854232464318e-09
56338 | 10628 | Txnip | TXNIP | thioredoxin interacting protein | -1.37465791866518 | 2.48125042812321e-06 | -1.90041036758697 | 9.38928240515904e-14
15903 | 3399 | Id3 | ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -1.3338917932709 | 2.42062973141413e-06 | -1.62663749522767 | 4.04181918190062e-11
20352 | 10509 | Sema4b | SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -1.29158665149443 | 1.08129405164895e-05 | -1.94044795574187 | 2.76811008855539e-13
20893 | 8553 | Bhlhe40 | BHLHE40 | basic helix-loop-helix family, member e40 | -1.27936445614615 | 3.1249941103339e-06 | -1.43040914673788 | 3.12034804217071e-10
15901 | 3397 | Id1 | ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -1.2360441953747 | 4.88262970544069e-07 | -1.16641587936635 | 2.30048514580509e-09
12122 | 637 | Bid | BID | [NAME] interacting domain death agonist | -1.22474182691632 | 1.373379681528e-06 | -1.07811034549607 | 1.36231774724564e-10
15368 | 3162 | [NAME] | HMOX1 | heme oxygenase (decycling) 1 | -1.22011122806392 | 1.56164732301968e-06 | -1.9235306330391 | 8.71644102702766e-13
319939 | 64759 | Tns3 | TNS3 | tensin 3 | -1.1292144323029 | 6.59594332161557e-06 | -1.56005899779409 | 3.66811050662123e-13
69573 | 29923 | 2310016C08Rik | C7orf68 | chromosome 7 open reading frame 68 | -1.11802813754755 | 7.00095945738305e-06 | -1.22027848467218 | 1.78123316366407e-10
23886 | 9518 | Gdf15 | GDF15 | growth differentiation factor 15 | -1.0501026604573 | 1.2265758370223e-05 | -2.1678876032182 | 6.04026171284103e-14
17927 | 4654 | Myod1 | MYOD1 | myogenic differentiation 1 | -1.04141093145165 | 3.57835522026027e-06 | -1.11297688486773 | 6.64656497744042e-10
12608 | 1051 | Cebpb | CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | -1.02119430295658 | 8.71741305272962e-06 | -2.44089557546266 | 6.503619427245e-16
93679 | 81603 | Trim8 | TRIM8 | tripartite motif containing 8 | -1.00955748336777 | 2.47086567032496e-05 | -1.18538697216043 | 1.34839246556235e-10
mouse [NAME] | human [NAME] | mouse Symbol | human Symbol | human [NAME] | C2C12 LogFC | C2C12 FDR | Human myo LogFC | Human myo [NAME]
68861 | 205428 | 1190002N15Rik | C3orf58 | chromosome 3 open reading frame 58 | 1.02057701717652 | 8.72475959445558e-06 | 1.64129627863058 | 2.73087009305949e-11
231225 | 202018 | Tapt1 | TAPT1 | transmembrane anterior posterior transformation 1 | 1.04739951353408 | 3.71636463599961e-06 | 1.13931014001344 | 1.23974388144175e-10
225358 | 51306 | Fam13b | FAM13B | family with sequence similarity 13, member B | 1.04923199565633 | 7.99216485253768e-06 | 1.10707421239021 | 2.98527081473489e-10
103554 | 23198 | Psme4 | PSME4 | proteasome (prosome, macropain) activator subunit 4 | 1.06029601177236 | 0.000212076313691404 | 1.14098719966747 | 9.77489994077262e-11
73124 | 27333 | Golim4 | GOLIM4 | golgi integral membrane protein 4 | 1.07790062202126 | 1.66280142991349e-05 | 1.01800861598998 | 2.08049222327923e-09
56194 | 55660 | Prpf40a | PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 1.08137564503431 | 2.48125042812321e-06 | 1.60701676044524 | 4.70954752157489e-13
70611 | 254170 | Fbxo33 | FBXO33 | F-box protein 33 | 1.10424919710346 | 5.72179765318447e-06 | 3.21991377301498 | 1.74881612872007e-17
58998 | 25945 | Pvrl3 | PVRL3 | poliovirus receptor-related 3 | 1.16437826189006 | 9.49908464167731e-07 | 2.31200610861021 | 4.46692402218571e-15
19736 | 5999 | Rgs4 | [NAME] | regulator of G-protein signaling 4 | 1.26653295593648 | 1.46824181476946e-05 | 1.95145318864977 | 5.07524003846263e-14
329727 | 163259 | Dennd2c | DENND2C | DENN/MADD domain containing 2C | 1.26932529599397 | 2.57749495978665e-06 | 2.60883529744818 | 5.10245379758188e-16
13653 | 1958 | Egr1 | EGR1 | early growth response 1 | 1.35980723324109 | 5.57559944732824e-07 | 3.7486636710802 | 1.86128383204739e-19
67279 | 51003 | Med31 | MED31 | mediator complex subunit 31 | 1.47480162883952 | 2.39671330471887e-07 | 2.05492458119926 | 1.79736195684203e-14
21420 | 7022 | Tcfap2c | TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 1.52241901754676 | 5.33048086083122e-07 | 1.49694540312028 | 1.20644805710698e-11
20677 | 6659 | Sox4 | SOX4 | SRY (sex determining region Y)-box 4 | 1.56356226396701 | 1.20310287968042e-05 | 1.80899793225564 | 2.05121686528721e-12
22289 | 7403 | Kdm6a | KDM6A | lysine (K)-specific demethylase 6A | 1.63372940924821 | 1.24196491399501e-05 | 1.17509333240898 | 3.21365894195778e-11
16911 | 8543 | Lmo4 | LMO4 | LIM domain only 4 | 1.95553378837702 | 8.21960671757515e-07 | 1.55749071774087 | 1.30866498546609e-12
28105 | 55521 | Trim36 | TRIM36 | tripartite motif containing 36 | 2.05218268197657 | 1.25090625444021e-07 | 1.321275284865 | 9.71101588272507e-10
399558 | 23768 | Flrt2 | FLRT2 | fibronectin leucine rich transmembrane protein 2 | 2.13086478997375 | 3.61986673312936e-08 | 1.04801586840241 | 1.6030302376825e-09
106042 | 144165 | Prickle1 | PRICKLE1 | prickle homolog 1 (Drosophila) | 2.180649772431 | 6.37328518216439e-08 | 1.04197279973669 | 8.12202772478275e-09
235493 | 56204 | BC031353 | KIAA1370 | KIAA1370 | 2.50768297544657 | 1.04912225996021e-07 | 1.30445959247252 | 1.67545042632432e-11
down in C2C12, up in human myos
mouse [NAME] | human [NAME] | mouse Symbol | human Symbol | human [NAME] | C2C12 LogFC | C2C12 FDR | Human myo LogFC | Human myo [NAME]
14219 | 1490 | Ctgf | CTGF | connective tissue growth factor | -1.36797709905394 | 1.1747587049896e-06 | 1.10870472570894 | 1.6039875602553e-09
up in C2C12, down in human myos
mouse [NAME] | human [NAME] | mouse Symbol | human Symbol | human [NAME] | C2C12 LogFC | C2C12 FDR | Human myo LogFC | Human myo [NAME]
56312 | 26471 | Nupr1 | NUPR1 | nuclear protein, transcriptional regulator, 1 | 1.18774957429237 | 1.23892980037035e-05 | -2.14416472234751 | 1.05549377569832e-10
216136 | 10994 | Ilvbl | ILVBL | ilvB (bacterial acetolactate synthase)-like | 1.68292583936658 | 1.373379681528e-06 | -1.01507385735107 | 1.07281730243457e-09
17988 | 10397 | Ndrg1 | NDRG1 | N-myc downstream regulated 1 | 1.86396258733139 | 3.61986673312936e-08 | -2.33220914226092 | 1.32498468481229e-15